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Search of human proteins with 7656879
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
(1163 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens] 2319 0.0
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 699 0.0
gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens] 650 0.0
gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens] 650 0.0
gi|87162461 fragile X mental retardation 2 [Homo sapiens] 634 0.0
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 150 9e-36
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 120 8e-27
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 111 5e-24
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 97 9e-20
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 97 9e-20
gi|60097902 filaggrin [Homo sapiens] 92 2e-18
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens] 91 6e-18
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 86 2e-16
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 85 4e-16
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 85 4e-16
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 84 6e-16
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 82 2e-15
gi|50962882 G patch domain containing 8 [Homo sapiens] 82 2e-15
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 82 4e-15
gi|57864582 hornerin [Homo sapiens] 80 9e-15
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 80 9e-15
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 80 1e-14
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 79 3e-14
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 79 3e-14
gi|52426735 ankyrin 2 isoform 1 [Homo sapiens] 77 7e-14
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 77 1e-13
gi|104526627 triadin [Homo sapiens] 75 4e-13
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 74 6e-13
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 74 6e-13
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 74 6e-13
>gi|7656879 ALL1 fused gene from 5q31 [Homo sapiens]
Length = 1163
Score = 2319 bits (6010), Expect = 0.0
Identities = 1163/1163 (100%), Positives = 1163/1163 (100%)
Query: 1 MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYD 60
MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYD
Sbjct: 1 MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYD 60
Query: 61 EMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS 120
EMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS
Sbjct: 61 EMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS 120
Query: 121 QKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSS 180
QKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSS
Sbjct: 121 QKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSS 180
Query: 181 PGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPP 240
PGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPP
Sbjct: 181 PGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPP 240
Query: 241 SLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKI 300
SLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKI
Sbjct: 241 SLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKI 300
Query: 301 PSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTG 360
PSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTG
Sbjct: 301 PSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTG 360
Query: 361 EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEG 420
EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEG
Sbjct: 361 EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEG 420
Query: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNK 480
ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNK
Sbjct: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNK 480
Query: 481 VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS 540
VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS
Sbjct: 481 VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS 540
Query: 541 ESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSR 600
ESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSR
Sbjct: 541 ESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSR 600
Query: 601 HKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLP 660
HKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLP
Sbjct: 601 HKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLP 660
Query: 661 PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDL 720
PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDL
Sbjct: 661 PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDL 720
Query: 721 NLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESK 780
NLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESK
Sbjct: 721 NLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESK 780
Query: 781 KPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSS 840
KPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSS
Sbjct: 781 KPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSS 840
Query: 841 LKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK 900
LKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK
Sbjct: 841 LKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK 900
Query: 901 PRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNA 960
PRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNA
Sbjct: 901 PRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNA 960
Query: 961 QESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKEN 1020
QESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKEN
Sbjct: 961 QESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKEN 1020
Query: 1021 ALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASG 1080
ALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASG
Sbjct: 1021 ALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASG 1080
Query: 1081 SSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASI 1140
SSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASI
Sbjct: 1081 SSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASI 1140
Query: 1141 MTDLVRYTRQGLHWLRQDAKLIS 1163
MTDLVRYTRQGLHWLRQDAKLIS
Sbjct: 1141 MTDLVRYTRQGLHWLRQDAKLIS 1163
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 699 bits (1804), Expect = 0.0
Identities = 482/1231 (39%), Positives = 678/1231 (55%), Gaps = 106/1231 (8%)
Query: 4 EDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK 63
+DRN+LR++E+ERRNQE Q ++AFP PLF EPYK T+K D+LSSRIQ+MLGNY+E+K
Sbjct: 10 DDRNLLRIREKERRNQEAHQEKEAFPEKIPLFGEPYK-TAKGDELSSRIQNMLGNYEEVK 68
Query: 64 DFIG--------DRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGP-- 113
+F+ D S +L P +P + +F H HQS GP
Sbjct: 69 EFLSTKSHTHRLDASENRLGKPKYPLIPDKGSSIPSSSFHTSVH---HQSIHTPASGPLS 125
Query: 114 ----APSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQH 169
+ + +Q R+ + S H A S +S DR GSS KKG
Sbjct: 126 VGNISHNPKMAQPRTEPMPSLH------AKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDR 179
Query: 170 ---GSEHSKSRSSSPGK--------PQAVSSLNSSHSRS------------HGNDHHSKE 206
G + S+P + P V L+ HS HG+ ++SK
Sbjct: 180 RADGDHCASVTDSAPERELSPLISLPSPVPPLSPIHSNQQTLPRTQGSSKVHGSSNNSKG 239
Query: 207 HQRSKSPRDPDA---NWDSPSRVPFSSGQHSTQSFPP-SLMSKSNSMLQKPTAYVRPMDG 262
+ +KSP+D + ++P + Q +Q+FPP SL SKS +M QKPTAYVRPMDG
Sbjct: 240 YCPAKSPKDLAVKVHDKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPTAYVRPMDG 299
Query: 263 Q-----ESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVD 317
Q ES E K E Y Q+ T+LK +KA LTKLK+PSQ ++ + S +V CV+
Sbjct: 300 QDQAPSESPELKPLPEDYRQQTF--EKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVE 357
Query: 318 EILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKT--SNGHQ 375
EILKEMTHSWPPPLTAIHTP EPSKFPFPTK+SQ + T QK+Y+ S SN Q
Sbjct: 358 EILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQ 417
Query: 376 -SKSMLKDDLKLSSSEDSDGEQDCDK----TMPRSTPGSNSEP--SHHNSEGADNSRDDS 428
+ SML+DDL+LS SEDSD EQ +K + P S P S EP S H+S +
Sbjct: 418 GTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSS--------A 469
Query: 429 SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSP 488
S S S+S S SDSESESSSSDSE NEP ++ +PEPEPP TNKWQLDNWL KV+ P
Sbjct: 470 ESESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPP 529
Query: 489 ASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPK-ETSSATPGRDSKTIQKGSESGRGRQ 547
+ P K + T ++++ P ++SS P + G R Q
Sbjct: 530 EGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGK---RSCQ 586
Query: 548 KSPAQSDSTTQRRTVGKKQPKKAEKAAAEE-PRGGLKIESET---PVDLASSMPSSRHKA 603
KSPAQ + QR+TVG KQPKK KA+A R L+ E E P + K
Sbjct: 587 KSPAQQEPP-QRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKV 645
Query: 604 ATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIET--DTSSSDSDESESLPP 661
TKG + E K + P++EKKK+KS+ + K+ E D + E +L P
Sbjct: 646 KTKGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVP 705
Query: 662 SSQTPKYPES---NRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKI 718
+++ P S +RT +V ++ + R+ P+ + +LLSPL + L+VKI
Sbjct: 706 LTESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKI 765
Query: 719 DLNLLTRIPGKPYKETEPPKGEKKNVP--EKHTREAQKQ-ASEKVSNKGKRKHKNEDDNR 775
L+LL+RIP P K + K E K P +KH+ E + +S K++ K K + + + DN+
Sbjct: 766 TLDLLSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNK 825
Query: 776 ASESKKP--KTEDKNSAGHKPSSNRESSKQSA-AKEKDLLPSPAGPVPSKDPKTEHGSRK 832
+K +S+ HK SS + S+ S+ + +K++LP P PV S K + K
Sbjct: 826 KIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPP--PVSSSSQKPAKPALK 883
Query: 833 RTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCP-P 891
R+ ++ + + ++ S+ SS KQ++ EGK S SS E K + +++ P P
Sbjct: 884 RSRREADTCGQDPPKSASSTKSNHKDSSIPKQRRVEGKGSRSSSEHKGSSGDTANPFPVP 943
Query: 892 SAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIE 951
S P +SKP + ++ FD + AD +++EAKK+K A+ ++DR KA YL+AV+SFIE
Sbjct: 944 SLPN-GNSKPGKPQVKFDKQQ--ADLHMREAKKMKQKAELMTDRVGKAFKYLEAVLSFIE 1000
Query: 952 CGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYL 1011
CG A E +Q SKS + +YSETVDLIK+ M LK++ A +K VLC+RC+S+L +
Sbjct: 1001 CGIATESESQSSKSAYSVYSETVDLIKFIMSLKSFSDATAPTQEKIFAVLCMRCQSILNM 1060
Query: 1012 RLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSS 1071
+F+ KK+ A+KYS+TL +H ++S +QAPSP + S G PSP+SP SP +S S
Sbjct: 1061 AMFRCKKDIAIKYSRTLNKHFESSSKVAQAPSPCIAS--TGTPSPLSPMPSPASSVGSQS 1118
Query: 1072 GASSASASGSSVTI--PQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDK 1129
A S +SG + TI P I M +SYV +TS+ L A ++W+QAE L+++ KEFFA L
Sbjct: 1119 SAGSVGSSGVAATISTPVTIQNMTSSYVTITSHVLTAFDLWEQAEALTRKNKEFFARLST 1178
Query: 1130 VMGPLIFNASIMTDLVRYTRQGLHWLRQDAK 1160
+ L N+S++ DLV YTRQG L++ K
Sbjct: 1179 NVCTLALNSSLV-DLVHYTRQGFQQLQELTK 1208
>gi|68348716 AF4/FMR2 family, member 3 isoform 2 [Homo sapiens]
Length = 1251
Score = 650 bits (1677), Expect = 0.0
Identities = 463/1271 (36%), Positives = 650/1271 (51%), Gaps = 182/1271 (14%)
Query: 5 DRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKD 64
DRN LR KERERRNQE QQ + F S LF+EPYK T+K D+LS+RIQ+ LGNYDEMKD
Sbjct: 48 DRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYK-TNKGDELSNRIQNTLGNYDEMKD 106
Query: 65 FIGDRSIPK-LVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSS--KWTPVGPAPSTSQSQ 121
F+ DRS LV +PKP VP + K + +F + SS T PA Q
Sbjct: 107 FLTDRSNQSHLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPAAVPVQQS 166
Query: 122 KRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSP 181
KR G+ +K H + R++
Sbjct: 167 KR------------------------------------GTMGWQKAGHPPSDGQQRATQQ 190
Query: 182 GKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHST-----Q 236
G + + D ++ R+K + + + R P + +HS+ Q
Sbjct: 191 GSLRTLLG-----------DGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSSGHCVQ 239
Query: 237 SFPPSLMSKSNSMLQKPTAYVRPMDGQESM---EPKLSSEHYSS----QSHGNSMTELKP 289
+FPPSL SK + + QKPTAYVRPMDGQ+ PKL S +S G ++ +P
Sbjct: 240 NFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSSETSVHCTSYRGVPASKPEP 299
Query: 290 S-SKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFP 348
+ +KA L+K IP Q ++ + SCV+EI++EMT W PPL+AI P K EP+KFPFP
Sbjct: 300 ARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMT--WLPPLSAIQAPGKVEPTKFPFP 357
Query: 349 TKESQQSNFGTGEQKRYN--PSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRST 406
K+SQ + G K+ + P NG + SML+DDLKLSS E+ + +Q +T R+
Sbjct: 358 NKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQRTALRAL 417
Query: 407 PGS------NSEPSHHNSEGADNSRDD--SSSHSGSESSSGSDSESESSSSDSEANEPSQ 458
S N S +S+G+ +S SSS S SESSSGSDSE+ESSSS+SE ++P
Sbjct: 418 SDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPH 477
Query: 459 SASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGRE--QGTGNSYT 516
+SPE EP +NKWQLD WLNKVNPHK +S+ S Y +E Q G
Sbjct: 478 FSSPEAEPASSNKWQLDKWLNKVNPHKPPILIQNESHGSESNQYYNPVKEDVQDCGK-VP 536
Query: 517 DTSGP----KETSSATPGRDS-KTIQKGSESGRGRQKSP--------------------- 550
D P KE S +T K S +QKSP
Sbjct: 537 DVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPPAVPCAP 596
Query: 551 AQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASS---MPSSRHKAATKG 607
A++ RR+ GKK ++ E+ +A + + E D + +P K G
Sbjct: 597 AENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCG 656
Query: 608 SRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPK 667
+ + + +KE +SS T EK++ + S+ KS+E IET++SSS S L S+ +
Sbjct: 657 NNRASHRKELRSSV--TCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDL--ESEQEE 712
Query: 668 YPESNRTPVKPSSVEEEDSFFRQRMFS--------------------------------P 695
YP S V S+ D ++ + P
Sbjct: 713 YPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTLVP 772
Query: 696 MEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPG----KPYKETEPPKGEKKNVPEKHTRE 751
ELLSPL + D+ L VKIDL LL+RIP +P + P + ++ P HT +
Sbjct: 773 FGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSD 832
Query: 752 AQKQASEKVSNKGKRKHK--NEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEK 809
+EK K KRK K NEDD R E K S G K SS+R ++ S
Sbjct: 833 TP---AEKALPKSKRKRKCDNEDDYR---------EIKKSQGEKDSSSRLATSTSNTLSA 880
Query: 810 DLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKN------SSSTSK 863
+ V K E R S + K S TS S N S+S+SK
Sbjct: 881 NHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSK 940
Query: 864 QKKTEGKTSSSSKEVKEKAPSSSSNCP---------PSAPTLDSSKP-RRTKLVFDDRNY 913
+ K + + ++ + A ++S N P P +P + + +R KLVFDD
Sbjct: 941 KPKADSQLQPHGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPR 1000
Query: 914 SADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSET 973
SAD+++QEAK++KH ADA+ ++F KA+ Y +A +SFIECGNA+E+ ESKSP+ MYSET
Sbjct: 1001 SADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSET 1060
Query: 974 VDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLK 1033
V+LI+Y M+LK + P+AT DK+L LC RC +LLY R+F+LK+++A+KYSK L ++ K
Sbjct: 1061 VELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFK 1120
Query: 1034 NSYNNSQAPSP-GLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSS--VTIPQKIH 1090
NS +QAPSP G K+ G PSP+SP SP +S S+ASA S V+IPQ+IH
Sbjct: 1121 NSSKAAQAPSPWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIH 1180
Query: 1091 QMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYTRQ 1150
QMAA++V +T++ L++ + W+ A+ L+KE +EFF +LD +MGP+ ++S M LV+Y++Q
Sbjct: 1181 QMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSS-MEHLVQYSQQ 1239
Query: 1151 GLHWLRQDAKL 1161
GLHWLR A L
Sbjct: 1240 GLHWLRNSAHL 1250
>gi|68348714 AF4/FMR2 family, member 3 isoform 1 [Homo sapiens]
Length = 1226
Score = 650 bits (1677), Expect = 0.0
Identities = 463/1271 (36%), Positives = 650/1271 (51%), Gaps = 182/1271 (14%)
Query: 5 DRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKD 64
DRN LR KERERRNQE QQ + F S LF+EPYK T+K D+LS+RIQ+ LGNYDEMKD
Sbjct: 23 DRNALRRKERERRNQETQQDDGTFNSSYSLFSEPYK-TNKGDELSNRIQNTLGNYDEMKD 81
Query: 65 FIGDRSIPK-LVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSS--KWTPVGPAPSTSQSQ 121
F+ DRS LV +PKP VP + K + +F + SS T PA Q
Sbjct: 82 FLTDRSNQSHLVGVPKPGVPQTPVNKIDEHFVADSRAQNQPSSICSTTTSTPAAVPVQQS 141
Query: 122 KRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSP 181
KR G+ +K H + R++
Sbjct: 142 KR------------------------------------GTMGWQKAGHPPSDGQQRATQQ 165
Query: 182 GKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHST-----Q 236
G + + D ++ R+K + + + R P + +HS+ Q
Sbjct: 166 GSLRTLLG-----------DGVGRQQPRAKQVCNVEVGLQTQERPPAMAAKHSSSGHCVQ 214
Query: 237 SFPPSLMSKSNSMLQKPTAYVRPMDGQESM---EPKLSSEHYSS----QSHGNSMTELKP 289
+FPPSL SK + + QKPTAYVRPMDGQ+ PKL S +S G ++ +P
Sbjct: 215 NFPPSLASKPSLVQQKPTAYVRPMDGQDQAPDESPKLKSSSETSVHCTSYRGVPASKPEP 274
Query: 290 S-SKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFP 348
+ +KA L+K IP Q ++ + SCV+EI++EMT W PPL+AI P K EP+KFPFP
Sbjct: 275 ARAKAKLSKFSIPKQGEESRSGETNSCVEEIIREMT--WLPPLSAIQAPGKVEPTKFPFP 332
Query: 349 TKESQQSNFGTGEQKRYN--PSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRST 406
K+SQ + G K+ + P NG + SML+DDLKLSS E+ + +Q +T R+
Sbjct: 333 NKDSQLVSSGHNNPKKGDAEPESPDNGTSNTSMLEDDLKLSSDEEENEQQAAQRTALRAL 392
Query: 407 PGS------NSEPSHHNSEGADNSRDD--SSSHSGSESSSGSDSESESSSSDSEANEPSQ 458
S N S +S+G+ +S SSS S SESSSGSDSE+ESSSS+SE ++P
Sbjct: 393 SDSAVVQQPNCRTSVPSSKGSSSSSSSGSSSSSSDSESSSGSDSETESSSSESEGSKPPH 452
Query: 459 SASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGRE--QGTGNSYT 516
+SPE EP +NKWQLD WLNKVNPHK +S+ S Y +E Q G
Sbjct: 453 FSSPEAEPASSNKWQLDKWLNKVNPHKPPILIQNESHGSESNQYYNPVKEDVQDCGK-VP 511
Query: 517 DTSGP----KETSSATPGRDS-KTIQKGSESGRGRQKSP--------------------- 550
D P KE S +T K S +QKSP
Sbjct: 512 DVCQPSLREKEIKSTCKEEQRPRTANKAPGSKGVKQKSPPAAVAVAVSAAAPPPAVPCAP 571
Query: 551 AQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASS---MPSSRHKAATKG 607
A++ RR+ GKK ++ E+ +A + + E D + +P K G
Sbjct: 572 AENAPAPARRSAGKKPTRRTERTSAGDGANCHRPEEPAAADALGTSVVVPPEPTKTRPCG 631
Query: 608 SRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPK 667
+ + + +KE +SS T EK++ + S+ KS+E IET++SSS S L S+ +
Sbjct: 632 NNRASHRKELRSSV--TCEKRRTRGLSRIVPKSKEFIETESSSSSSSSDSDL--ESEQEE 687
Query: 668 YPESNRTPVKPSSVEEEDSFFRQRMFS--------------------------------P 695
YP S V S+ D ++ + P
Sbjct: 688 YPLSKAQTVAASASSGNDQRLKEAAANGGSGPRAPVGSINARTTSDIAKELEEQFYTLVP 747
Query: 696 MEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPG----KPYKETEPPKGEKKNVPEKHTRE 751
ELLSPL + D+ L VKIDL LL+RIP +P + P + ++ P HT +
Sbjct: 748 FGRNELLSPLKDSDEIRSLWVKIDLTLLSRIPEHLPQEPGVLSAPATKDSESAPPSHTSD 807
Query: 752 AQKQASEKVSNKGKRKHK--NEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEK 809
+EK K KRK K NEDD R E K S G K SS+R ++ S
Sbjct: 808 TP---AEKALPKSKRKRKCDNEDDYR---------EIKKSQGEKDSSSRLATSTSNTLSA 855
Query: 810 DLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKN------SSSTSK 863
+ V K E R S + K S TS S N S+S+SK
Sbjct: 856 NHCNMNINSVAIPINKNEKMLRSPISPLSDASKHKYTSEDLTSSSRPNGNSLFTSASSSK 915
Query: 864 QKKTEGKTSSSSKEVKEKAPSSSSNCP---------PSAPTLDSSKP-RRTKLVFDDRNY 913
+ K + + ++ + A ++S N P P +P + + +R KLVFDD
Sbjct: 916 KPKADSQLQPHGGDLTKAAHNNSENIPLHKSRPQTKPWSPGSNGHRDCKRQKLVFDDMPR 975
Query: 914 SADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSET 973
SAD+++QEAK++KH ADA+ ++F KA+ Y +A +SFIECGNA+E+ ESKSP+ MYSET
Sbjct: 976 SADYFMQEAKRMKHKADAMVEKFGKALNYAEAALSFIECGNAMEQGPMESKSPYTMYSET 1035
Query: 974 VDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLK 1033
V+LI+Y M+LK + P+AT DK+L LC RC +LLY R+F+LK+++A+KYSK L ++ K
Sbjct: 1036 VELIRYAMRLKTHSGPNATPEDKQLAALCYRCLALLYWRMFRLKRDHAVKYSKALIDYFK 1095
Query: 1034 NSYNNSQAPSP-GLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSS--VTIPQKIH 1090
NS +QAPSP G K+ G PSP+SP SP +S S+ASA S V+IPQ+IH
Sbjct: 1096 NSSKAAQAPSPWGASGKSTGTPSPMSPNPSPASSVGSQGSLSNASALSPSTIVSIPQRIH 1155
Query: 1091 QMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYTRQ 1150
QMAA++V +T++ L++ + W+ A+ L+KE +EFF +LD +MGP+ ++S M LV+Y++Q
Sbjct: 1156 QMAANHVSITNSILHSYDYWEMADNLAKENREFFNDLDLLMGPVTLHSS-MEHLVQYSQQ 1214
Query: 1151 GLHWLRQDAKL 1161
GLHWLR A L
Sbjct: 1215 GLHWLRNSAHL 1225
>gi|87162461 fragile X mental retardation 2 [Homo sapiens]
Length = 1311
Score = 634 bits (1634), Expect = 0.0
Identities = 484/1319 (36%), Positives = 681/1319 (51%), Gaps = 187/1319 (14%)
Query: 4 EDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKV---TSKEDKLSSRIQSMLGNYD 60
+DR+ L+ +E ERRNQE+QQ +D F LF EPYKV T+K D L++R+Q+ LGNYD
Sbjct: 20 QDRSALKKREWERRNQEVQQEDDLFSSGFDLFGEPYKVAEYTNKGDALANRVQNTLGNYD 79
Query: 61 EMKDFIGDRSIPK-LVAIPKPTVPPSADEKSNPNFFEQRHGG---SHQSSKWTPVGPAPS 116
EMK+ + + S LV IPK +VP + + K+ P+FF ++ HQ + P P P
Sbjct: 80 EMKNLLTNHSNQNHLVGIPKNSVPQNPNNKNEPSFFPEQKNRIIPPHQDNTH-PSAPMPP 138
Query: 117 TSQSQKRSSGLQSGHSSQ----RTSAGSSS--GTNSSGQRHDRESYNNSGSSSRKKG--Q 168
S S+ + S S+ R S S+ + +SGQ + ++ S ++ +
Sbjct: 139 PSVVILNSTLIHSNRKSKPEWSRDSHNPSTVLASQASGQPNKMQTLTQDQSQAKLEDFFV 198
Query: 169 HGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSP----- 223
+ +E + P S+ S+ S G D KE +S SP + + +P
Sbjct: 199 YPAEQPQIGEVEESNP---SAKEDSNPNSSGEDAF-KEIFQSNSPEESEFAVQAPGSPLV 254
Query: 224 --SRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQES---MEPKLSSEHYSSQ 278
S + SSG S Q+FPP L K++ QKPTAYVRPMDGQ+ + P L
Sbjct: 255 ASSLLAPSSGL-SVQNFPPGLYCKTSMGQQKPTAYVRPMDGQDQAPDISPTLKPSIEFEN 313
Query: 279 SHGN----SMTELKPSSKAHLTKLKIPS--QPLDASASGDVSCVDEILKEMTHSWPPPLT 332
S GN ++ + KPS+ + TKL + Q + S D SCV+EIL+EMTHSWP PLT
Sbjct: 314 SFGNLSFGTLLDGKPSAASSKTKLPKFTILQTSEVSLPSDPSCVEEILREMTHSWPTPLT 373
Query: 333 AIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSK--TSNGHQSKSMLKDDLKLSSSE 390
++HT +E S F P +ESQ G QK +P+ ++ KSML+DDLKLSS E
Sbjct: 374 SMHTAGHSEQSTFSIPGQESQHLTPGFTLQKWNDPTTRASTKSVSFKSMLEDDLKLSSDE 433
Query: 391 D--------------SDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSES 436
D ++ Q +K PR+ P N + A + S S S SES
Sbjct: 434 DDLEPVKTLTTQCTATELYQAVEKAKPRNNP-VNPPLATPQPPPAVQASGGSGSSSESES 492
Query: 437 SSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVS--------P 488
SS SDS++ESS++DSE+NE + A+PEPEPP TNKWQLD WLNKV S P
Sbjct: 493 SSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQNKSFICGQNETP 552
Query: 489 ASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDS---KTIQKGSESGRG 545
++ P Q + + + + N+ + PKE + R+ + QK E+
Sbjct: 553 METISLPPPIIQPMEVQMKVKT--NASQVPAEPKERPLLSLIREKARPRPTQKIPETKAL 610
Query: 546 RQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLK--IESETPVDLAS----SMPSS 599
+ K S++ +QR T+GKKQPKK EK + + K I S TP + S P
Sbjct: 611 KHKLSTTSETVSQR-TIGKKQPKKVEKNTSTDEFTWPKPNITSSTPKEKESVELHDPPRG 669
Query: 600 RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS--DESE 657
R+KA + KP +KE + + EKKKY+ K KSRE IETD+S+SDS D+ E
Sbjct: 670 RNKAT---AHKPAPRKEPRPNIPLAPEKKKYRGPGKIVPKSREFIETDSSTSDSNTDQEE 726
Query: 658 SL-----PP----SSQTPKYPE------------SNRTPVKPSSVEEEDSFFRQRMFSPM 696
+L PP T K E S+ S+ E+ F P+
Sbjct: 727 TLQIKVLPPCIISGGNTAKSKEICGASLTLSTLMSSSGSNNNLSISNEEPTFSP---IPV 783
Query: 697 EEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQA 756
+ E+LSPL + ++ L VKIDL+LL+R+PG P K + K K R+ A
Sbjct: 784 MQTEILSPLRDHENLKNLWVKIDLDLLSRVPGHSSLHAAPAKPDHKETATKPKRQTAVTA 843
Query: 757 SEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSA-----------GHKPSSNRESSKQSA 805
EK + KGKRKHK + KK + E+ + HKP + RE++
Sbjct: 844 VEKPAPKGKRKHKPIEVAEKIPEKKQRLEEATTICLLPPCISPAPPHKPPNTRENNSSRR 903
Query: 806 A---KEKDLLPSPAGPVPSKDPKTEHGS-------RKRTISQSSSLKSSSNSNKETS--- 852
A KE+ L P P P+P P+ + S + + I+ + + S+ E
Sbjct: 904 ANRRKEEKLFPPPLSPLPEDPPRRRNVSGNNGPFGQDKNIAMTGQITSTKPKRTEGKFCA 963
Query: 853 ---GSSKNSSSTSKQKK--------------TEGKTSSSSKEVKEKAPSSSSNCPPSA-- 893
G S N T K+ T T+ + V A ++++ +
Sbjct: 964 TFKGISVNEGDTPKKASSATITVTNTAIATATVTATAIVTTTVTATATATATTTTTTTTI 1023
Query: 894 -------------------------PTLDSSKP--RRTKLVFDDRNYSADHYLQEAKKLK 926
P L SS RR KL FDD ++AD+Y+QEAKKLK
Sbjct: 1024 STITSTITTGLMDSSHLEMTSWAALPLLSSSSTNVRRPKLTFDDSVHNADYYMQEAKKLK 1083
Query: 927 HNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNY 986
H ADAL ++F KAV Y DA +SF ECGNA+E++ E+KSP+ MYSETV+L++Y M+LKN+
Sbjct: 1084 HKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMRLKNF 1143
Query: 987 LAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLK-NSYNNSQAPSPG 1045
+P A+ DK+L VLC RC SLLYLR+FKLKK++A+KYS++L E+ K N+ +Q PSP
Sbjct: 1144 ASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVAQIPSPW 1203
Query: 1046 LGSKAVGMPSPVS-PKLSPGNS-GNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNF 1103
+ S PSPVS +SP N+ GN ++G VTIPQ+IH MAAS+V +TSN
Sbjct: 1204 V-SNGKNTPSPVSLNNVSPINAMGNCNNG---------PVTIPQRIHHMAASHVNITSNV 1253
Query: 1104 LYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYTRQGLHWLRQDAKLI 1162
L E WD A++L++E KEFF +LD +MGPL ++S MT+LVRY RQGL WLR DA L+
Sbjct: 1254 LRGYEHWDMADKLTRENKEFFGDLDTLMGPLTQHSS-MTNLVRYVRQGLCWLRIDAHLL 1311
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 150 bits (378), Expect = 9e-36
Identities = 166/799 (20%), Positives = 277/799 (34%), Gaps = 51/799 (6%)
Query: 116 STSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSK 175
S S S S+ S SS S+ S+S ++S D ++S SS S+ S
Sbjct: 550 SDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSD 609
Query: 176 SRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHST 235
S SS + S +SS S S +D SK + D N DS S+ S+
Sbjct: 610 SSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS 669
Query: 236 QSFPPSLMSKSN--SMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKA 293
S S S S+ S + + ES + SS+ SS S +S + S +
Sbjct: 670 DSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSS 729
Query: 294 HLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQ 353
+ + S D+S S D S + + S + +S
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSD------------------SSDSSDSSNSSDSSDSS 771
Query: 354 QSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEP 413
S+ + + + +SN S +SS+ SD D S+ SNS
Sbjct: 772 DSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSD 831
Query: 414 SHHNSEGADNS-RDDSSSHSGSESSSGSDSESESSSSDS-EANEPSQSASPEPEPPPTNK 471
S +S +D+S DSS S S+SS+ SDS + S SSDS +++ S S+ +N
Sbjct: 832 SSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891
Query: 472 WQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGR 531
+ N + ++S DS+ S+ E ++ +D+S ++S ++
Sbjct: 892 SDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSS 951
Query: 532 DSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVD 591
+S S+S S + S ++ +++ +S D
Sbjct: 952 NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 592 LASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSS 651
+ S SS ++ S + S SS + S S +S S + ++ SS
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 652 DSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDR 711
SD S+S S + SN + SS + S + S S+ D
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSS-----------DSSDSSDSSDSSD- 1119
Query: 712 YPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNE 771
+ + + +SE + +
Sbjct: 1120 -----------------SSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162
Query: 772 DDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSR 831
D+ S ++ NS+ SS+ S S+ S + ++
Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222
Query: 832 KRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPP 891
+ S S +SS +S+ S S NSS +S + TS S+ E ++ S + N
Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNG 1282
Query: 892 SAPTLDSSKPRRTKLVFDD 910
S DS DD
Sbjct: 1283 SDSDSDSEGSDSNHSTSDD 1301
Score = 144 bits (364), Expect = 4e-34
Identities = 173/859 (20%), Positives = 297/859 (34%), Gaps = 25/859 (2%)
Query: 85 SADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGT 144
++D + +F ++ G +S G + S+S SS + S + +G+
Sbjct: 446 NSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGS 505
Query: 145 NSSGQRHDRE--SYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSH-GND 201
+S G D + + + S S G +G++ + S GK + S +S S S +D
Sbjct: 506 DSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD 565
Query: 202 HHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD 261
+ S S D D++ S S S+ S S S S+ + D
Sbjct: 566 SSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSD 625
Query: 262 GQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILK 321
+S S+ S S NS S + + S D+S S D S +
Sbjct: 626 SSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSN 685
Query: 322 EMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLK 381
S + + S + S SN + + N S +S+ S
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSD--- 742
Query: 382 DDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSD 441
SS+ SD D + S+ SNS S +S+ +D+S D S+S ++SS+ SD
Sbjct: 743 ------SSDSSDSSNSSDSS--DSSDSSNSSDSSDSSDSSDSS-DSSNSSDSNDSSNSSD 793
Query: 442 SESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQG 501
S S+SSDS + S +S + +N N + + S +S + S
Sbjct: 794 SSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDS 853
Query: 502 YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
+ + +D+S +S ++ DS S+S S + S ++
Sbjct: 854 DSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSD 913
Query: 562 VGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSP 621
++ +S D + S SS ++ S N S S+
Sbjct: 914 SSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNS 973
Query: 622 RPTAEKKKYKSTSKSSQKSREIIETDTS----SSDSDESESLPPSSQTPKYPESNRTPVK 677
+++ +S SS S +D+S SSDS +S SS + +S+ +
Sbjct: 974 SDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDS 1033
Query: 678 PSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPP 737
S + DS S + S S+ D D + +
Sbjct: 1034 SDSSDSSDSSDS----SDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSD 1089
Query: 738 KGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSN 797
+ + +S+ + N D+ S ++ NS+ SS
Sbjct: 1090 SSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSE 1149
Query: 798 RESSKQSA--AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSS 855
S S+ + D S S + S S SS SS+S+ + S
Sbjct: 1150 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1209
Query: 856 KNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSA 915
+ SS S +S SS + S SS+ S+ + DSS + D N +
Sbjct: 1210 SSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDES 1269
Query: 916 DHYLQEAKKLKHNADALSD 934
D + + +D+ SD
Sbjct: 1270 DSQSKSGNGNNNGSDSDSD 1288
Score = 126 bits (316), Expect = 1e-28
Identities = 158/773 (20%), Positives = 267/773 (34%), Gaps = 79/773 (10%)
Query: 85 SADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGT 144
S+D + + + SK +S S +S S S ++ SS +
Sbjct: 601 SSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 145 NSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHS 204
NSS +S ++S SSS + S+ S S SS + SS +S S +D +
Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSN 720
Query: 205 KEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQE 264
S S D++ S S S S S SNS D +
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS-----------SDSSD 769
Query: 265 SMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMT 324
S + SS+ +S +S S ++ + S D+S S D
Sbjct: 770 SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD------------ 817
Query: 325 HSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDL 384
S + S S+ + + S +S+G S S + D
Sbjct: 818 ----------------SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDS 861
Query: 385 KLS--SSEDSDGEQDCDKT-MPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGS- 440
S SS+ SD D + S SNS S +S +D+ DSS+ S S SS S
Sbjct: 862 SNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSS 921
Query: 441 -DSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSS 499
SES +SS +S +++ S S+ +N N + N S ++S DS+ S+
Sbjct: 922 DSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSN 981
Query: 500 QGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR 559
+ + + +D+S ++S ++ DS S S S + S +
Sbjct: 982 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSD 1041
Query: 560 RTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKS 619
+ ++ + + +S D + S SS ++ S + S S
Sbjct: 1042 SSDSSDSSDSSDSSNSS--------DSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNS 1093
Query: 620 SPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPS 679
S + S S S S + ++ SS SD S+S SS + +S+ +
Sbjct: 1094 SDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS-SDSSDSSNSSDSSDSSESSD 1152
Query: 680 SVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKG 739
S + DS S + S S+ D N ++
Sbjct: 1153 SSDSSDS-------SDSSDSSDSSDSSDSSD--------SSNSSDSSDSSDSSDSSDSSD 1197
Query: 740 EKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRE 799
+ + ++ + S+ + D N +S+S ++ +S+ SS+
Sbjct: 1198 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDS-SDSSDSSDSSNSSDSSDSS 1256
Query: 800 SSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETS 852
S S + D D +++ G+ S S S S+SN TS
Sbjct: 1257 DSSDSTSDSND----------ESDSQSKSGNGNNNGSDSDSDSEGSDSNHSTS 1299
Score = 125 bits (315), Expect = 2e-28
Identities = 175/861 (20%), Positives = 306/861 (35%), Gaps = 69/861 (8%)
Query: 117 TSQSQKRSSGLQSGHSSQRT-------------------------SAGSSSGTN------ 145
TS+S++ S+G+ + SQR + G S
Sbjct: 322 TSKSEENSAGIPEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIEIKGP 381
Query: 146 SSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPG----------KPQAVSSLNSSHS 195
SSG R+ + KGQHG K + G K + + + S++
Sbjct: 382 SSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGNKVGHSNT 441
Query: 196 RSHGN-DHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPT 254
S N D + KS + D N S + S + + NS K
Sbjct: 442 GSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYNSDESKDN 501
Query: 255 AYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVS 314
G E + +S+ +S S+GN + K+ K K S D+S S + S
Sbjct: 502 GNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSS 561
Query: 315 -CVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNG 373
D + + S ++ + S + S SN + + + S S+
Sbjct: 562 DSSDSSDSDSSDS----NSSSDSDSSDSDSSDSSDSDSSDSSN--SSDSSDSSDSSDSSD 615
Query: 374 HQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSG 433
S K D S S+ SD + D + S+ S++ S +S + NS D S S
Sbjct: 616 SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDS-SDSSNSSNSSDSSDSSDS 674
Query: 434 SESSSGSDSESESSSSDS--EANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASS 491
S+SSS SDS + S SSDS +N S S + ++ + N + + + S
Sbjct: 675 SDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734
Query: 492 VDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPA 551
DS+ S + + +D+S ++S ++ DS S+S S +
Sbjct: 735 SDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDS 794
Query: 552 QSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKP 611
S + + ++ + ++ S D ++S SS ++ GS
Sbjct: 795 SDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGS--- 851
Query: 612 NIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPES 671
+S SS R + S S S S + + SSDS+ES + SS + +S
Sbjct: 852 ----DSDSSNRSDSSNSSDSSDSSDSSNSSD----SSDSSDSNESSNSSDSSDSSNSSDS 903
Query: 672 NRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPY 731
+ + SS + S S E S S D D + +
Sbjct: 904 DSSDSSNSSDSSDSS-----NSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958
Query: 732 KETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAG 791
+ + + ++ + S+ + D + +S+S +S
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 792 HKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKET 851
S++ +SS S + + + S D S + S SS S S+ + ++
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078
Query: 852 SGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSS-SSNCPPSAPTLDSSKPRRTKLVFDD 910
S SS++S S+ ++ SS S + + + SS SS+ S+ + DSS + D
Sbjct: 1079 SDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDS 1138
Query: 911 RNYSADHYLQEAKKLKHNADA 931
N S E+ ++D+
Sbjct: 1139 SNSSDSSDSSESSDSSDSSDS 1159
Score = 117 bits (293), Expect = 6e-26
Identities = 165/802 (20%), Positives = 295/802 (36%), Gaps = 90/802 (11%)
Query: 125 SGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKP 184
+GL + S + SG D E+ N SS+ KGQ G +H K
Sbjct: 237 AGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKE-------- 288
Query: 185 QAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMS 244
H S G + SKE+ + DP D G +++S
Sbjct: 289 -------DDHDSSIGQNSDSKEYYDPEGKEDPHNEVD---------GDKTSKS------- 325
Query: 245 KSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQP 304
++ +A + +G + +E H S+ N +T K S + K +
Sbjct: 326 ------EENSAGIPEDNGSQRIEDTQKLNHRESKRVENRIT--KESETHAVGKSQDKGIE 377
Query: 305 LDASASGDVSCVDEILK-----EMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT 359
+ +SG+ + E+ K E L + + E P ++S+ N
Sbjct: 378 IKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSEPGN-KV 436
Query: 360 GEQKRYNPSKTSNGHQS-----KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPS 414
G + S S+G+ S KSM DD +SS++S+G D + S +NS
Sbjct: 437 GHSNTGSDSN-SDGYDSYDFDDKSMQGDDP--NSSDESNGNDDAN-----SESDNNSSSR 488
Query: 415 HHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQL 474
S +D S+D+ + S S+ + DS+S S +++S++N + + + + + K +
Sbjct: 489 GDASYNSDESKDNGNG-SDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKS 547
Query: 475 DNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSK 534
D+ + + S SS S+ SS + + +S + S ++S ++ DS
Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDS--NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSS 605
Query: 535 TIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKK--AEKAAAEEPRGGLKIESETPVDL 592
S+S S ++SDS+ K ++ +++ +S +
Sbjct: 606 DSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNS 665
Query: 593 ASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSD 652
+ S SS ++ S N S SS + + S S S S ++++SSD
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Query: 653 SDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRY 712
SD S S SS + +S+ + +S + DS S S S+ D
Sbjct: 726 SDSSNS-SDSSDSSNSSDSSDSSDSSNSSDSSDS-------SDSSNSSDSSDSSDSSDSS 777
Query: 713 PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNED 772
D N ++ + + ++ + SN + ++
Sbjct: 778 DSSNSSDSN-----DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832
Query: 773 DNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRK 832
+ ++ S + D + SSNR S S+ S D S
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSS--------------DSSDSSDSSNSSD 878
Query: 833 RTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPS 892
+ S S+ S+S+ + ++S SS + SS S +S+SS + S +SN S
Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDS 938
Query: 893 APTLDSSKPRRTKLVFDDRNYS 914
+ + DSS + D N S
Sbjct: 939 SNSSDSSDSSDSSNSSDSSNSS 960
Score = 115 bits (288), Expect = 2e-25
Identities = 167/846 (19%), Positives = 285/846 (33%), Gaps = 87/846 (10%)
Query: 85 SADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGT 144
S + N + + +K V P S G SG+ + S
Sbjct: 203 SCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDD 262
Query: 145 NSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHS 204
+ ++S NNS KGQ G +H K H S G + S
Sbjct: 263 EDEEAGNGKDSSNNS------KGQEGQDHGK---------------EDDHDSSIGQNSDS 301
Query: 205 KEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQE 264
KE+ + DP D S + ++ P S+ QK R E
Sbjct: 302 KEYYDPEGKEDPHNEVDGDKT---SKSEENSAGIPEDNGSQRIEDTQKLNH--RESKRVE 356
Query: 265 SMEPKLSSEHYSSQSHGNSMTELKPSS-KAHLTK--------LKIPSQPLDASASGDVSC 315
+ K S H +S + PSS ++TK + Q G+V
Sbjct: 357 NRITKESETHAVGKSQDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKT 416
Query: 316 VDEI--LKEMTHSWPPPLTAIHTPCKTEPS-----KFPFPTKESQQSNFGTGEQKRYNPS 368
E+ ++ P H+ ++ + + F K Q + + ++ N
Sbjct: 417 QGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDD 476
Query: 369 KTSNGHQSKSMLKDDLKLSSSE--------DSDGEQDCDKTMPRSTPGSNSEPSHHNSEG 420
S + S + D +S E DS G +D D ST +N+ S+ N
Sbjct: 477 ANSESDNNSSS-RGDASYNSDESKDNGNGSDSKGAEDDDSD---STSDTNNSDSNGNGNN 532
Query: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNK 480
++ D S S G SS SDS S+SSDS + S S+ +
Sbjct: 533 GNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDS---------- 582
Query: 481 VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS 540
+ S +S DS+ S+ + + + +D+S K SS + S + K
Sbjct: 583 -SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSD 641
Query: 541 ESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSR 600
S S SDS+ + + ++ +S + D ++S SS
Sbjct: 642 SSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSS----------DSSSSSDSSNSSDSSD 691
Query: 601 HKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLP 660
++ S + S S +++ S+ S S + ++ SS SD S+S
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 661 PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRM-------FSPMEEKELLSPLSEPDDRYP 713
S + SN + SS + S S + S S D
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 714 LIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDD 773
D + + N + S+ S+ + D
Sbjct: 812 SSDSSD----SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867
Query: 774 NRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKR 833
+ +S+S +S ++ S++ +SS S + + D S + S D S +
Sbjct: 868 SDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDS-SNSSDSSDSSNSSDSSES 926
Query: 834 TISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSA 893
+ S +S S S+++ ++S SS +S+S+ ++ SS S + S SSN S+
Sbjct: 927 SNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986
Query: 894 PTLDSS 899
+ DSS
Sbjct: 987 DSSDSS 992
Score = 82.4 bits (202), Expect = 2e-15
Identities = 94/385 (24%), Positives = 147/385 (38%), Gaps = 9/385 (2%)
Query: 85 SADEKSNPNFFEQRHGG-SHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSG 143
S+D + N + + S SS + + ++S S S S SS S+ SS
Sbjct: 920 SSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDS 979
Query: 144 TNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSS--LNSSHSRSHGND 201
+NSS +S ++S SS S+ S S SS + SS NSS S +
Sbjct: 980 SNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDS 1039
Query: 202 HHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRP-- 259
S + S D + DS S S+ S S S+S+ +
Sbjct: 1040 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDS 1099
Query: 260 MDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEI 319
D +S + SS+ S NS S + + S D+S S D S +
Sbjct: 1100 SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDS 1159
Query: 320 LKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSM 379
S + + S + +S S+ + + S +S+ S
Sbjct: 1160 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1219
Query: 380 LKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSG 439
D S S DS+ D + S+ SNS S +S+ +D S DS+ S S+S SG
Sbjct: 1220 -SDSSDSSDSSDSNESSDSSDSSD-SSDSSNSSDSSDSSDSSD-STSDSNDESDSQSKSG 1276
Query: 440 SDSESES-SSSDSEANEPSQSASPE 463
+ + + S S SDSE ++ + S S +
Sbjct: 1277 NGNNNGSDSDSDSEGSDSNHSTSDD 1301
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 120 bits (301), Expect = 8e-27
Identities = 117/548 (21%), Positives = 220/548 (40%), Gaps = 70/548 (12%)
Query: 411 SEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTN 470
+E + E + ++ G E G + E+E ++++ ++ASPE E
Sbjct: 461 TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV 520
Query: 471 KWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPG 530
K + + +P K S + + S + K +E+ S + P++ + +P
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAE--VKSPEKAKSPAKEEA--KSPPEAKSPEKEEAKSPA 576
Query: 531 RDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK---KQPKKAEKAAAEEPRGGLKIES- 586
+ K+ +K + KSPA++ S + ++ K K P +A+ EE + +++S
Sbjct: 577 -EVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635
Query: 587 ---ETPVDLASSMPSS-----RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQ 638
++P + P + +A + K +K E+KS P K K+ +KS +
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS---PEKAKSPVKAEAKSPE 692
Query: 639 KSREIIETDTSSSDSDES----ESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFS 694
K++ ++ + S + +S E+ P E +TP K S +E++ ++ S
Sbjct: 693 KAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKS 752
Query: 695 PMEEK-------ELLSPLSE----PDDRYPLIVKIDLNLLTRIPGK-------------- 729
P + K E +P E P D++P K + + P K
Sbjct: 753 PEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK 812
Query: 730 ----------PYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASES 779
P KE E P+ K P K E + A+ K K K +++ E+
Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEK---KDSKKEEAPKKEA 869
Query: 780 KKPKTEDKNS-AGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSK-------DPKTEHGSR 831
KPK E+K A KP ++ +K+ A++K +P+P P+K PK +
Sbjct: 870 PKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVA 929
Query: 832 KRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPP 891
K+ + + + S + K+ + K + K KK E K + +K ++ S P
Sbjct: 930 KKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKP 989
Query: 892 SAPTLDSS 899
A + S
Sbjct: 990 KAEKAEKS 997
Score = 100 bits (250), Expect = 6e-21
Identities = 112/543 (20%), Positives = 225/543 (41%), Gaps = 51/543 (9%)
Query: 360 GEQKRYNP---SKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHH 416
GE++ +P S ++KS +K++ K + S +++ +P P+
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 417 NSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDN 476
++ ++ + S + S +++S + + EA P+++ SPE P K + +
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKE-EAKSPAEAKSPEKAKSPV-KEEAKS 614
Query: 477 WLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTI 536
+P K S + P K + + S P++ + +P + +
Sbjct: 615 PAEAKSPVKEEAKSPAEVKSPE----KAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPV 670
Query: 537 QKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSM 596
+ ++S + KSP ++++ + + K P K E + E+ + +K E+++P S +
Sbjct: 671 KAEAKSPE-KAKSPVKAEAKSPEKA---KSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV 726
Query: 597 PSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDES 656
+ +A T K +K+E+KS + + +K KS + E S +D
Sbjct: 727 ---KEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPE 783
Query: 657 ESLPPSSQTPKYPESNRTPVKPSS-VEEEDSFFRQRMFSPMEEKELLS-------PLSEP 708
++ P + K PE ++P+K + E++ ++ + SP++E+E P
Sbjct: 784 KAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAE 843
Query: 709 DDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRK- 767
+++ P K + ++ P KE PK E+K P + K ++K + K+K
Sbjct: 844 EEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKV 903
Query: 768 -----------HKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPA 816
ED +++ K E ++ +PS E K+ AA EK
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAE--KKEAAPEKKDTKEEK 961
Query: 817 GPVPSKDPKTEHGSRK--RTISQSSSL-------KSSSNSNKETSGSSKNSSSTSKQKKT 867
P + PKTE +++ +T+S+ S KSSS K+ SK ++ K
Sbjct: 962 AKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKD----SKPPEKATEDKAA 1017
Query: 868 EGK 870
+GK
Sbjct: 1018 KGK 1020
Score = 82.8 bits (203), Expect = 2e-15
Identities = 86/375 (22%), Positives = 155/375 (41%), Gaps = 51/375 (13%)
Query: 552 QSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKP 611
Q++ T V +++ K+A++ +E GG + E+E + S P+ + K ++ P
Sbjct: 460 QTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSP 519
Query: 612 NIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPES 671
+K+E+KS P K K +KS E+ + + S + E PP +++P+ E+
Sbjct: 520 -VKEEAKS---PAEAKSPEKEEAKS---PAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEA 572
Query: 672 NRTPVKPSSVEEEDSFFRQRMFSPMEEK---ELLSPLSEPDDRYPLIVKIDLNLLTRIPG 728
++P + S E+ S ++ SP E K + SP+ E
Sbjct: 573 -KSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKE--------------------- 610
Query: 729 KPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN 788
E + P K V E+ A+ ++ EK + K + K+ + ++ E ++ K+ +K
Sbjct: 611 ----EAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKA 666
Query: 789 SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSN 848
+ K + +S K + P A K P E S K+ S
Sbjct: 667 KSPVKAEAKSPEKAKSPVKAEAKSPEKA-----KSPVKEEA--------KSPEKAKSPVK 713
Query: 849 KETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVF 908
+E K S ++ KT K S KE + K+P + + P A TLD P
Sbjct: 714 EEAKSPEKAKSPVKEEAKTPEKAKSPVKE-EAKSPEKAKS-PEKAKTLDVKSPEAKTPAK 771
Query: 909 DDRNYSADHYLQEAK 923
++ AD + ++AK
Sbjct: 772 EEARSPADKFPEKAK 786
Score = 60.8 bits (146), Expect = 7e-09
Identities = 108/579 (18%), Positives = 199/579 (34%), Gaps = 67/579 (11%)
Query: 96 EQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRES 155
E+ GG ++ +P ++ + + +S + S + S + E
Sbjct: 492 EEAEGGEEETK--SPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEK 549
Query: 156 YNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRD 215
+ K K + SP + ++ S + +K +++KSP
Sbjct: 550 AKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVK 609
Query: 216 PDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHY 275
+A + ++ P S KS + PT + +S E S E
Sbjct: 610 EEAKSPAEAKSPVKEEAKSPAEV------KSPEKAKSPT-----KEEAKSPEKAKSPEKE 658
Query: 276 SSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIH 335
++S + + +K +K+ K K P + S S V E K
Sbjct: 659 EAKSPEKAKSPVKAEAKSP-EKAKSPVKAEAKSPEKAKSPVKEEAK-------------- 703
Query: 336 TPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSK--TSNGHQSKSMLKDDLKLSSSEDSD 393
P K P KE +S +K +P K ++KS +K++ K S +
Sbjct: 704 -----SPEKAKSPVKEEAKS-----PEKAKSPVKEEAKTPEKAKSPVKEEAK---SPEKA 750
Query: 394 GEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSES----ESSSS 449
+ KT+ +P + + AD + + S E S ++S ++ +
Sbjct: 751 KSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAP 810
Query: 450 DSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQ 509
+ E + + SP E + ++ K K +PA+ P ++ K +E+
Sbjct: 811 EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK-APAT------PKTEEKKDSKKEE 863
Query: 510 GTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKK 569
+ PK P ++K ES +K A+ T K+ P K
Sbjct: 864 APKK---EAPKPKVEEKKEP-----AVEKPKESKVEAKKEEAEDKKKVP--TPEKEAPAK 913
Query: 570 AEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPR---PTAE 626
E +P+ ++ + P D + PS + K + K+E P T
Sbjct: 914 VEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEA 973
Query: 627 KKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT 665
K K + S + S+ E SS +D+ +S PP T
Sbjct: 974 KAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKAT 1012
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 111 bits (277), Expect = 5e-24
Identities = 205/934 (21%), Positives = 337/934 (36%), Gaps = 137/934 (14%)
Query: 24 GEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVA------I 77
G++ P P E +++ +K + R+++ G D D G P+ A
Sbjct: 107 GKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVD--GSSFDPQRRAREAKQPA 164
Query: 78 PKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTS 137
P+P P S +S+ SS+ P P + +K+ G S+ +S
Sbjct: 165 PEPPKPYSLVRESS-------------SSR----SPTPKQKKKKKKKD---RGRRSESSS 204
Query: 138 AGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRS 197
+S ++H ES + KK +H S KS+ S K + SRS
Sbjct: 205 PRRERKKSSKKKKHRSESES-------KKRKHRSPTPKSKRKSKDKKR-------KRSRS 250
Query: 198 HGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQ-HSTQSFPPSLMSKSNSMLQKPTAY 256
S+ RS S ++ S SR ++ + H+T S S + +
Sbjct: 251 TTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPF 310
Query: 257 VRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCV 316
P G S + S E + Q +S E K K + + P +S +
Sbjct: 311 SEP--GTTSTQRPSSPETATKQP--SSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAP 366
Query: 317 DEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQS 376
+L E P PL TP EP P ++ + +K S + + S
Sbjct: 367 TPLLAERHGGSPQPLAT--TPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPS 424
Query: 377 KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE----PSHHNSEGADNSRDDSSSHS 432
K SSS +S P PGS+ E P+ N RD S SH+
Sbjct: 425 PQPTKVSRHASSSPESP--------KPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHT 476
Query: 433 GSESSSGSDSESESSSSDSEANEP-----SQSASPE-PEPPPTNKW-------------- 472
S S S + + S + P S+S SP+ +W
Sbjct: 477 PSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRS 536
Query: 473 -QLDNWLNKVNPHKVSPASSV-----DSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526
Q W N + + S S P+++G + G S + T + + S
Sbjct: 537 PQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRS 596
Query: 527 ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586
TP R + + GR R ++PA+ S T + P + + R + S
Sbjct: 597 RTPTRRRSRSRTPARRGRSRSRTPARRRSRT-------RSPVRRRSRSRSPARRSGRSRS 649
Query: 587 ETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTS--KSSQKSREII 644
TP S + + SR P ++ +S R A + + +S + + +SR ++
Sbjct: 650 RTPARRGRSRSRTPARRGRSRSRTP-ARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLV 708
Query: 645 ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSP 704
S S + + SS K +RT + S + R+ S + L SP
Sbjct: 709 RRGRSHSRTPQRRGRSGSSSERK--NKSRTSQRRSRSNSSPEMKKSRI-SSRRSRSLSSP 765
Query: 705 LSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKG 764
S+ R L+L + G + P +K P + +R Q K
Sbjct: 766 RSKAKSR--------LSLRRSLSG-----SSPCPKQKSQTPPRRSRSGSSQPKAKSRTPP 812
Query: 765 KRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDP 824
+R +R+S S PK + K PS SS K K P G + S
Sbjct: 813 RR-------SRSSSSPPPKQKSKT-----PSRQSHSSSSPHPKVKSGTPPRQGSITSPQA 860
Query: 825 KTEHGS-RKRTISQSS---SLKSSSNSNKETSGSS-KNSSSTSKQKKTEGKTSSSSKEVK 879
+ + ++R+ +SS LKS + S SGSS S++ +++ ++SS +VK
Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVK 920
Query: 880 ------EKAPSSSSNCPPSAPTLDSSKPRRTKLV 907
+++ S SS+ PS T + PRR++ V
Sbjct: 921 AIISPRQRSHSGSSSPSPSRVT-SRTTPRRSRSV 953
Score = 90.1 bits (222), Expect = 1e-17
Identities = 180/843 (21%), Positives = 291/843 (34%), Gaps = 120/843 (14%)
Query: 114 APSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRE-SYNNSGSSSRKKGQHGSE 172
+P +S+ RS +SG S RT A + + R R S + S R + + +
Sbjct: 629 SPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPAR 688
Query: 173 HSKSRSSSPGKPQAVSSLNSSHSRSH----------GNDHHSKEHQRSKSPRDPDANWDS 222
+SRS +P + ++ S RSH G+ K R+ R +
Sbjct: 689 RGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE 748
Query: 223 PSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGN 282
+ SS + + S P S +KS L++ + P Q+S P S SSQ
Sbjct: 749 MKKSRISSRRSRSLSSPRS-KAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAK 807
Query: 283 SMTELK----PSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPC 338
S T + SS K K PS+ +S+S ++ PP +I +P
Sbjct: 808 SRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH--------PKVKSGTPPRQGSITSPQ 859
Query: 339 KTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDC 398
E S P + S + E K PS+ S S +K
Sbjct: 860 ANEQSVTP--QRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS--------------- 902
Query: 399 DKTMPRSTPGSNSEP-------------SHHNSEGADNSRDDSSSHSGSESSSGSDSESE 445
T PR +P +S P SH S SR S + S S E
Sbjct: 903 --TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVE 960
Query: 446 SSS----SDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQG 501
S S S ++ P PE P ++ + + KV S S P Q
Sbjct: 961 SRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPY-PKVKAQTPPGPSLSGSKSPCPQE 1019
Query: 502 YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
K+ Q S + +G K SS PG + G+ + +SD+++
Sbjct: 1020 KSKDSLVQSCPGSLSLCAGVK--SSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVR 1077
Query: 562 VGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKK-ESKSS 620
+ + + P+GG S +LAS P + + + S P +K S
Sbjct: 1078 QSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRG--EFSASPMLKSGMSPEQ 1135
Query: 621 PRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS 680
R ++ Y + +S + +ET ++S E +LPP P + P
Sbjct: 1136 SRFQSDSSSYPTVDSNSLLGQSRLET----AESKEKMALPPQEDATASPPRQKDKFSPFP 1191
Query: 681 VE---EEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPP 737
V+ E F+ + +P E+ E ++ + T
Sbjct: 1192 VQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSAL-----------------PTSSQ 1234
Query: 738 KGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSN 797
E V EK +++ A + +S+ + N S P+ E++ + +
Sbjct: 1235 DEELMEVVEK----SEEPAGQILSHLSSELKEMSTSNFES---SPEVEERPAVSLTLDQS 1287
Query: 798 RESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLK--------------S 843
+ + A + + S GP S + K S R S S L+
Sbjct: 1288 QSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGF 1347
Query: 844 SSNSNKETSGSSKNSSSTS-----KQKKTEGKTSSSSK---EVKEKAPSSSSNCPPSAPT 895
SS ++ +G N T K++ T SSS+ + EKA SSN S+P
Sbjct: 1348 SSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKA-GMSSNQSISSPV 1406
Query: 896 LDS 898
LD+
Sbjct: 1407 LDA 1409
Score = 76.6 bits (187), Expect = 1e-13
Identities = 199/918 (21%), Positives = 335/918 (36%), Gaps = 141/918 (15%)
Query: 31 SSPLFAEPYKVTSKEDK----LSSRIQSMLGNYDEMKDFIGDRSIPKLVAIPKPTVPPSA 86
S+P P + +S + K +S R +S G+ + R+ P+ +V P +
Sbjct: 902 STPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRR----SRSVSPCS 957
Query: 87 DEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNS 146
+ +S R+ S SS T V P QS S +Q S SG+ S
Sbjct: 958 NVESR---LLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKS 1014
Query: 147 S-GQRHDRESYNNS--GSSSRKKGQHGSEHSKSRSSSPGKPQ-AVSSLNSSHSRSHGNDH 202
Q ++S S GS S G S + PG+ VSSL DH
Sbjct: 1015 PCPQEKSKDSLVQSCPGSLSLCAGVKSS-------TPPGESYFGVSSLQLKGQSQTSPDH 1067
Query: 203 HSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAY--VRPM 260
S + SP ++ +SPS Q +Q+ P S+S+S + + + +R
Sbjct: 1068 RSD----TSSPEVRQSHSESPSL------QSKSQTSPKGGRSRSSSPVTELASRSPIRQD 1117
Query: 261 DGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEIL 320
G+ S P L S QS S + P+ +D+++ S ++
Sbjct: 1118 RGEFSASPMLKSGMSPEQSRFQSDSSSYPT--------------VDSNSLLGQSRLETAE 1163
Query: 321 KEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSML 380
+ + PP A +P + + PFP ++ +S+ + R P + S S
Sbjct: 1164 SKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETK 1223
Query: 381 KDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGS 440
+ + L +S +++ + + +S + SH +SE + S + S E
Sbjct: 1224 EQNSALPTSSQ---DEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAV 1280
Query: 441 D---SESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIP 497
+S+S +S PS ++S W PH SP SN P
Sbjct: 1281 SLTLDQSQSQASLEAVEVPSMASS----------WG--------GPH-FSPEHKELSNSP 1321
Query: 498 ---SSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSD 554
+S G E R G + +T E G ++ Q + +
Sbjct: 1322 LRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGH 1381
Query: 555 STTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS------ 608
S+++ P EKA + +PV A SR ++++ S
Sbjct: 1382 SSSEL------SPDAVEKAGMSSNQS-----ISSPVLDAVPRTPSRERSSSASSPEMKDG 1430
Query: 609 --RKPNIKKESKSSP--RPTAEKKKYKSTSKSSQKSREIIETDTSS----SDSDESESLP 660
R P+ + S SSP R + S S SS ++I T + S E ++LP
Sbjct: 1431 LPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALP 1490
Query: 661 ----PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIV 716
P S++P PE N + P R S +++K + R
Sbjct: 1491 QTPRPRSRSPSSPELNNKCLTPQRE-------RSGSESSVDQKTVARTPLGQRSRSGSSQ 1543
Query: 717 KIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRA 776
++D+ + ++ P K P + + ++ +S +V +K + + R+
Sbjct: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLR--QRSRSGSSPEVDSKSRLSPR-----RS 1596
Query: 777 SESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDP-KTEHGSRKRTI 835
P+ +DK A + S +SS P P P P P ++ GS +
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSS-----------PEPKAPAPRALPRRSRSGSSSKGR 1645
Query: 836 SQSSSLKSSSNSNKE---TSGSSKNSSSTSKQKKTEGKT------SSSSKEVKEKAP-SS 885
S SS+ S+ E S +++ S +S + KT+ +T S SS E+ KA S
Sbjct: 1646 GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSR 1705
Query: 886 SSNCPPSAPTLDSSKPRR 903
S S+P S P R
Sbjct: 1706 RSRSASSSPETRSRTPPR 1723
Score = 74.3 bits (181), Expect = 6e-13
Identities = 181/891 (20%), Positives = 302/891 (33%), Gaps = 160/891 (17%)
Query: 97 QRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNS--------SG 148
Q G S S +P QS S LQS SQ + G S ++S S
Sbjct: 1056 QLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQS--KSQTSPKGGRSRSSSPVTELASRSP 1113
Query: 149 QRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQ 208
R DR + S S K G E S+ +S S P S NS +S SKE
Sbjct: 1114 IRQDRGEF--SASPMLKSGM-SPEQSRFQSDSSSYPTVDS--NSLLGQSRLETAESKEKM 1168
Query: 209 RSKSPRD----PDANWDSPSRVPFSSGQHSTQSFPPSLMS---------KSNSMLQKPTA 255
D P D S P S+ F +L + S ++ +A
Sbjct: 1169 ALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA 1228
Query: 256 YVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKL----KIPSQPLDASASG 311
+E ME SE + Q + +ELK S ++ + P+ L S
Sbjct: 1229 LPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQ 1288
Query: 312 DVSCVDEI-LKEMTHSWPPP-LTAIHTPCKTEP---SKFPFPTKESQQSNFGTGEQKRYN 366
+ ++ + + M SW P + H P + F P + GT ++
Sbjct: 1289 SQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFS 1348
Query: 367 P-------------------------SKTSNGHQSKSMLKDDLK---LSSSEDSDG---- 394
S S+GH S + D ++ +SS++
Sbjct: 1349 SEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLD 1408
Query: 395 --------EQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESES 446
E+ + P G PS + G+ D S S SGS +
Sbjct: 1409 AVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKD 1468
Query: 447 SSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEG 506
+SPEP+ P P SP+S +N + ++ G
Sbjct: 1469 IPRTPSRGRSECDSSPEPKALPQTP----------RPRSRSPSSPELNNKCLTPQRERSG 1518
Query: 507 REQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQ 566
E + + S + G + K S S + R +S + DS + RT
Sbjct: 1519 SESSVDQKTVARTPLGQRSRS--GSSQELDVKPSASPQERSESDSSPDSKAKTRT----- 1571
Query: 567 PKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAE 626
P + + P +++S++ + S S + K P + S SSP P A
Sbjct: 1572 PLRQRSRSGSSP----EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAP 1627
Query: 627 KKK---YKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT--------PKYPESNRTP 675
+ +S S SS K R + SS ++ S PP S+T P+ +RTP
Sbjct: 1628 APRALPRRSRSGSSSKGRG--PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTP 1685
Query: 676 VKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYK--E 733
+ S R+ S + S S P+ R +R P + +
Sbjct: 1686 PRRRSSRSSPELTRKARLS----RRSRSASSSPETR------------SRTPPRHRRSPS 1729
Query: 734 TEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRK-------HKNEDDNRASESKKPKTED 786
P+ +K+ + R A ++ S +G+ ++ +R +++ + D
Sbjct: 1730 VSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
Query: 787 KNSAGHKPSSNRE------------------SSKQSAAKEKDLLPSPAGPVPSKDPKTEH 828
++ + S R+ S+ A +E S S+ P T
Sbjct: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPT-- 1847
Query: 829 GSRKRTISQSSSL---KSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSK 876
SRKR+ S++S +S S ++ T S++ + ++++ +TS S+
Sbjct: 1848 -SRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSR 1897
Score = 70.5 bits (171), Expect = 9e-12
Identities = 161/832 (19%), Positives = 284/832 (34%), Gaps = 75/832 (9%)
Query: 113 PAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSE 172
P S +S+ R+S + S RTS + + R S + + +R++ + +
Sbjct: 1881 PLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTP 1940
Query: 173 HSKSRSSSPGKP---QAVSSLNSSHSRSHGNDHHSK-EHQRSKSPRDPDANWDSPSRVPF 228
++ RS S P + S +R S +RS+S P S SR
Sbjct: 1941 TTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSP 2000
Query: 229 SSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSS---QSHGNSMT 285
+ + S P +S S + P A R + + P+ S S + S T
Sbjct: 2001 VTRRRSRSRTSPVTRRRSRS--RTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
Query: 286 ELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKF 345
K LT+ P SASG S + + S PP T H+ +T P
Sbjct: 2059 PRTARGKRSLTRS--PPAIRRRSASGSSS-------DRSRSATPPATRNHSGSRTPPVAL 2109
Query: 346 PFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRS 405
S+ S F + + + + +S + + G D PR
Sbjct: 2110 ----NSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSM-MDGPGPRI 2164
Query: 406 TPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP- 464
P H + +N + + + S G+ S S+ A SQ +P P
Sbjct: 2165 -------PDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPL 2217
Query: 465 ------------EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQ-GT 511
P N + P + + DS P++ +
Sbjct: 2218 MSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAV 2277
Query: 512 GNSYTDTSGPKETSSA--------TPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVG 563
S + + P+ ++ TP + GS + P+ S + +
Sbjct: 2278 APSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASAN 2337
Query: 564 KKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPR- 622
P+ A A G + P L S+ + A S + + + S R
Sbjct: 2338 LVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRT 2397
Query: 623 --PTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS 680
P ++ + ++ + +SR + ++ + S S P S P + R+PV +
Sbjct: 2398 SPPLLDRARSRTPPSAPSQSR--MTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAF 2455
Query: 681 VEEEDSFFRQRMFSPMEEKELLSP------LSEPDDRYPLIVKIDLNLLTRIPGKPYKET 734
++ Q +P+ + LS S D + L PG P+ +
Sbjct: 2456 SDQSRCLIAQT--TPVAGSQSLSSGAVATTTSSAGDHNGM-------LSVPAPGVPHSDV 2506
Query: 735 -EPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHK 793
EPP P A + A E+ S+ + + +S S + +S+ +
Sbjct: 2507 GEPPASTGAQQPS--ALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 794 PSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSG 853
SS + + + P+P V P ++++ S SSS SSS+S+ +S
Sbjct: 2565 GSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624
Query: 854 SSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTK 905
SS +SSS+S + +SSSS P + P++P RR++
Sbjct: 2625 SSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676
Score = 66.6 bits (161), Expect = 1e-10
Identities = 131/625 (20%), Positives = 215/625 (34%), Gaps = 84/625 (13%)
Query: 70 SIPKLVAIPKPTVP----PSADEKSNPNFFEQRHGGSHQSS------KWTPVGPAPSTSQ 119
S P+ A+P+ P PS+ E +N QR +SS TP+G +
Sbjct: 1482 SSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGS 1541
Query: 120 SQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSS 179
SQ+ ++ S Q S SS + + R + SGSS + S S RS
Sbjct: 1542 SQELD--VKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK--SRLSPRRSR 1597
Query: 180 SPGKPQAVSSLNSSHSRSHGNDH--HSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQS 237
S P+ ++ G+D K PR + S R P G ST+S
Sbjct: 1598 SGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTES 1657
Query: 238 FPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTK 297
P P + + S EPK S + S EL + KA L++
Sbjct: 1658 SPE----------HPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPEL--TRKARLSR 1705
Query: 298 LKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNF 357
+ AS+S P T TP + S + +++S
Sbjct: 1706 -----RSRSASSS-------------------PETRSRTPPRHRRSPSVSSPEPAEKSRS 1741
Query: 358 GTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHN 417
+ +P + + +S L S + T R GS+ S
Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRR 1801
Query: 418 SEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNW 477
SR GS S S + ESS + S PPT++
Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRR------GRSRTPPTSR------ 1849
Query: 478 LNKVNPHKVSPASSVDSNIPSSQGYKKEGREQ----GTGNSYTDTSGPKETSSATPGRDS 533
K + + SPA S +S + R + S + TS S + +
Sbjct: 1850 --KRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVT 1907
Query: 534 KTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLA 593
+ + S R++S +++ T+RR+ + + + P + S TP
Sbjct: 1908 RRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTP---- 1963
Query: 594 SSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS 653
P +R ++ ++ S P ++ S+S P + +S S++S +R + TS
Sbjct: 1964 ---PVTRRRSRSRTS--PITRRRSRSRTSPVTRR---RSRSRTSPVTRRRSRSRTSPVTR 2015
Query: 654 DESESLPPSSQTPKYPESNRTPVKP 678
S S P + + +RTP+ P
Sbjct: 2016 RRSRSRTPPAIRRR--SRSRTPLLP 2038
Score = 62.4 bits (150), Expect = 2e-09
Identities = 105/474 (22%), Positives = 171/474 (36%), Gaps = 79/474 (16%)
Query: 102 SHQSSKWTPVGPAPSTSQSQKRSSGLQSGH-SSQRTSAGSSSGTNSSGQRHDRESYNNSG 160
++ SS TP PA + + + + + RT+A + + +S + + + +
Sbjct: 2322 NYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARM--APALSGAN 2379
Query: 161 SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANW 220
+S + E R+S P L+ + SR+ + ++P
Sbjct: 2380 LTSPRVPLSAYERVSGRTSPP-------LLDRARSRTPPSAPSQSRMTSERAPSPSSRMG 2432
Query: 221 DSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSH 280
+PS+ Q +S PS S + L A P+ G +S+ + SS
Sbjct: 2433 QAPSQSLLPPAQDQPRSPVPSAFSDQSRCL---IAQTTPVAGSQSLSSGAVATTTSSAGD 2489
Query: 281 GNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKT 340
N M L +P+ + S G+ PP T P
Sbjct: 2490 HNGM-------------LSVPAPGVPHSDVGE---------------PPASTGAQQPSAL 2521
Query: 341 EPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGE----- 395
+ P KE + S+ + + S +S+ S S SSS DS+G
Sbjct: 2522 AALQ---PAKERRSSSSSSSSSSSSSSSSSSSSSSSSSG-------SSSSDSEGSSLPVQ 2571
Query: 396 -QDCDKTMPRSTPGSNSE----------PSHHNSEGADNSRDDSSSHSGSESSSGSDSES 444
+ K +P TP P+ + +S SSS S S SSS S S S
Sbjct: 2572 PEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS 2631
Query: 445 ESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNP---HKVSPASSVDSNIPS-SQ 500
SSSS S ++ S S+SP P P K P SP +DS S S
Sbjct: 2632 SSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSL 2691
Query: 501 GYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKG---SESGRGRQKSPA 551
Y R + + P++ S++ R S+ Q+G S S + R+++P+
Sbjct: 2692 SYSPVERRRP-----SPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS 2740
Score = 55.8 bits (133), Expect = 2e-07
Identities = 160/809 (19%), Positives = 272/809 (33%), Gaps = 113/809 (13%)
Query: 119 QSQKRSSGLQSGHSSQRTSAGSSSGTNS-SGQRHDRESYNNSGSSSRKKGQHGSE---HS 174
+S+ R+S + S RTS + + S + R S + + RK+ + S
Sbjct: 1993 RSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRR 2052
Query: 175 KSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHS 234
+SRS +P + SL S RS+S P S SR P
Sbjct: 2053 RSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTP------- 2105
Query: 235 TQSFPPSLMSKSNSMLQKPTAYVRPMDGQES---MEPKLSSEHYSS---QSHGNSMTELK 288
P +L S S +P+ P+D S +EP SS S Q+ G+ M
Sbjct: 2106 ----PVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPG 2161
Query: 289 PSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFP 348
P H + +P A ++ + T PP ++A + S+ P P
Sbjct: 2162 PRIPDH-QRTSVPEN----HAQSRIALALTAISLGTARPPPSMSAAGLAARM--SQVPAP 2214
Query: 349 TKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPG 408
P+ ++ S + + + M ++P
Sbjct: 2215 VPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPR 2274
Query: 409 SNSEPSHHNSEGADNSRDDSSSHSGSESSSG--SDSESESSSSDSEANEPSQSASPEPEP 466
+ PS N + + +G+ + + + S + S + + AN PS S +P+
Sbjct: 2275 TAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPA 2334
Query: 467 PPTNKWQLDNWLNKVNPHKVSPASSVDSNI-----PSSQGYKKEGREQGTGNSYTDTSGP 521
N + + H +P + S P+S + +G + T P
Sbjct: 2335 SA-------NLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPAL-SGANLTSPRVP 2386
Query: 522 KETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT-----VGKKQPKKAEKAAAE 576
GR S + + S R +P+QS T++R +G+ + A +
Sbjct: 2387 LSAYERVSGRTSPPLLDRARS-RTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQD 2445
Query: 577 EPRGGLK----------IESETPVDLASSMPSSRHKAATKGSRK---------PNIKKES 617
+PR + I TPV + S+ S T + P +
Sbjct: 2446 QPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD 2505
Query: 618 KSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVK 677
P P + + S + Q ++E + +SSS S S S SS + S+ + +
Sbjct: 2506 VGEP-PASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE 2564
Query: 678 PSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPP 737
SS+ + +R+ SP T P + +E PP
Sbjct: 2565 GSSLPVQPEVALKRVPSP----------------------------TPAPKEAVREGRPP 2596
Query: 738 KGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSN 797
+ P K R + +S S+ + +S S + +S+ SS+
Sbjct: 2597 EP----TPAKRKRRSSSSSSSSSSSSSS--------SSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 798 RESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSR--KRTISQSSSLKSSSNSNKETSGSS 855
SS A LP PA P K P E SR ++ I +S S S E S
Sbjct: 2645 SSSSPSPAKPGPQALPKPAS--PKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPS 2702
Query: 856 KNSSSTSKQKKTEGKTSSSSKEVKEKAPS 884
S +Q + + S + ++PS
Sbjct: 2703 PQPSPRDQQSSSSERGSRRGQRGDSRSPS 2731
Score = 52.0 bits (123), Expect = 3e-06
Identities = 80/384 (20%), Positives = 136/384 (35%), Gaps = 61/384 (15%)
Query: 425 RDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASP----EPEPPPTNKWQLDNWLNK 480
R S + + S S SE S S PSQS P +P P + + +
Sbjct: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463
Query: 481 VNPHKVSPASSVDSNIPSSQGYKKEGREQGT------GNSYTD------TSGPKETSSAT 528
V+ + S+ S ++ G G G ++D ++G ++ S+
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTT-SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALA 2522
Query: 529 PGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLK-IESE 587
+ +K + S S S + S S++ + G + +P LK + S
Sbjct: 2523 ALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSP 2582
Query: 588 TPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETD 647
TP ++ R T RK S SS ++ S+S SS S +
Sbjct: 2583 TPAP-KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641
Query: 648 TSSSDSDESESLP-----PSSQTPKYP----ESNRTPVKPSSVEEEDSFFRQRMFSPMEE 698
+SSS S S + P P +PK P +R+P KP + R +SP+E
Sbjct: 2642 SSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDS---RSLSYSPVER 2698
Query: 699 KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASE 758
+ P +P P+ ++ + E+ +R Q+ S
Sbjct: 2699 RR---PSPQPS---------------------------PRDQQSSSSERGSRRGQRGDSR 2728
Query: 759 KVSNKGKRKHKNEDDNRASESKKP 782
S+K +R+ + R S+ P
Sbjct: 2729 SPSHKRRRETPSPRPMRHRSSRSP 2752
Score = 46.6 bits (109), Expect = 1e-04
Identities = 58/279 (20%), Positives = 106/279 (37%), Gaps = 35/279 (12%)
Query: 643 IIETDTSSSDSDESESLPPS-SQTPKYPESNRTPVKP--SSVEEEDSFFRQRMFSPMEE- 698
++E D + +E+ P+ ++T + E N + ++ DS+ F P
Sbjct: 98 LLEKDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGISDSYVDGSSFDPQRRA 157
Query: 699 KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASE 758
+E P EP Y L+ + + +R P K+ + K + R +K++S+
Sbjct: 158 REAKQPAPEPPKPYSLVRE---SSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSK 214
Query: 759 KVSNKG-----KRKHKNEDDNRASESKKPKTEDKNSAGHKPSS----------------- 796
K ++ KRKH++ +SK K + S P S
Sbjct: 215 KKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDT 274
Query: 797 NRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSK 856
+R S+ +AAK + P P+ G S+ + + S+ ET+
Sbjct: 275 SRSRSRSAAAKTHTTALAGRSPSPASG---RRGEGDAPFSEPGTTSTQRPSSPETATKQP 331
Query: 857 NSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPT 895
+S K K + K+++ E+ SS+ P APT
Sbjct: 332 SSPYEDKDKDKKEKSATRPSPSPER---SSTGPEPPAPT 367
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 97.1 bits (240), Expect = 9e-20
Identities = 203/994 (20%), Positives = 368/994 (37%), Gaps = 155/994 (15%)
Query: 130 GHSSQRTSAGSSSGTNSSGQRHDRESYNNSG-SSSRKKGQHGSEHSKSRSSSPGKPQAVS 188
G+++ S++ N S +R + NS + R++ G + +SR+ P+ +S
Sbjct: 810 GYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLS 869
Query: 189 SLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNS 248
+ + + + + SKE + +P D N R G+ S P L+ S
Sbjct: 870 ARDGHNQKDNTK---SKEKESENAPGDGKGNKHKKHRKR-RKGEESEGFLNPELLETSRK 925
Query: 249 MLQKPTA---------YVRPM--DGQESMEPKLSSEH--YSSQSHGNSMTELKPSSKAHL 295
++PT +V P D + + +E + S S + KP +K
Sbjct: 926 S-REPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 984
Query: 296 TKLKIPSQPLDAS------ASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPT 349
TK K + A G VD + S PP A KT+ +K +
Sbjct: 985 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTK---SS 1041
Query: 350 KESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGS 409
SQ+ TG ++ + ++K + ++ +K S+D E+ K P
Sbjct: 1042 SSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNE 1101
Query: 410 NSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPE---P 466
++P + E ++ G D + ESSS E ++ P P+
Sbjct: 1102 KNKPLDNKGEKRKRKTEEK----------GVDKDFESSSMKISKLEVTEIVKPSPKRKME 1151
Query: 467 PPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526
P T K +D K +PA + N ++ G++ G+ + ++T P E
Sbjct: 1152 PDTEK--MDRTPEKDKISLSAPAKKIKLN-------RETGKKIGSTENISNTKEPSEKLE 1202
Query: 527 ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586
+T S Q + GK + K G + S
Sbjct: 1203 ST------------------------SSKVKQEKVKGKVRRKVT----------GTEGSS 1228
Query: 587 ETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREII-- 644
T VD S+ ++T GS P K E K+ + T K + + ++ + ++I
Sbjct: 1229 STLVDYTST-------SSTGGS--PVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIM 1279
Query: 645 -ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLS 703
+ S D D+ ES + K + + KP+SV + S + E++
Sbjct: 1280 IQVPQSKWDKDDFES---EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---- 1332
Query: 704 PLSEPDDRYPLIVKIDLNLLTRIPGKPYKET-EPPKGEKKN----VPEKHTREAQKQAS- 757
SEP ++ K + + + K K + KG+ K+ V EK E +K ++
Sbjct: 1333 --SEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQ 1390
Query: 758 -EKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPA 816
EK SN + + + + SK+ +T DK+ + + SSN++ +
Sbjct: 1391 PEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDST-RASSNKDFT--------------- 1434
Query: 817 GPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEG----KTS 872
P++D KT++ +R+ + S+ K+ K++ +K+S+S K K E K
Sbjct: 1435 ---PNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1491
Query: 873 SSSKEVKEKAPSSSSNCPPSAPTLDSSKPRR-TKLVFDDRNYSADHYLQEAKKLKHNADA 931
+ + +PS T D+ +P TK V + + ++ EA+ K ++
Sbjct: 1492 TGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSG- 1550
Query: 932 LSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLA--P 989
K +Y L+ + +E + + + P P S + L + + A P
Sbjct: 1551 -----NKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEP 1605
Query: 990 DATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKT-LTEHLKNSYNNSQAPSPGLGS 1048
D +D V ES N K K + E K S + + G+
Sbjct: 1606 DYNESDSESNVSVKEEES----------SGNISKDLKDKIVEKAKESLDTAAVVQVGISR 1655
Query: 1049 KAVGMPSPVSPKLSPGNSGNYSSGASSASASGSS 1082
VSP S SG+ + SS+++S S
Sbjct: 1656 NQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAES 1689
Score = 67.4 bits (163), Expect = 8e-11
Identities = 153/803 (19%), Positives = 280/803 (34%), Gaps = 88/803 (10%)
Query: 96 EQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRES 155
++++ GS S K V PA G Q +R + S + ++
Sbjct: 986 KRKNDGSAVSKKENIVKPA----------KGPQEKVDGERERSPRSEPPIKKAKEETPKT 1035
Query: 156 YNNSGSSSRKK-----GQHGSEHSKS-RSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQR 209
N SSS +K G HSKS + KP + +S+ ++ + + ++
Sbjct: 1036 DNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEK 1095
Query: 210 SKSPRDPDANWDSPS--RVPFSSGQHSTQSFPPSLMSKSN---SMLQKPTAYVRPMDGQE 264
+K P + + D+ R + + + F S M S + + KP+ + E
Sbjct: 1096 AKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTE 1155
Query: 265 SME-----PKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASG--DVSCVD 317
M+ K+S + + N T K S +++ K PS+ L++++S
Sbjct: 1156 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1215
Query: 318 EILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT--GEQKRYNPSKTSNGHQ 375
++ +++T + T + + P E + T + YN T+
Sbjct: 1216 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAED 1275
Query: 376 SKSMLKDDLKLSSSEDSDGEQ-DCDKTMPRSTPGS--------NSEPSH------HNSEG 420
M++ +D + E+ D T P S+ G +++PS+ SE
Sbjct: 1276 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP 1335
Query: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNK 480
++ + + S S S+SS+ + + E E P K N
Sbjct: 1336 SEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK-------NS 1388
Query: 481 VNPHKVSPASSVDS--NIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQK 538
P K S ++ N S KE R T + + D++ TP RD KT
Sbjct: 1389 TQPEKESNLDRLNEQGNFKSLSQSSKEAR---TSDKH-DSTRASSNKDFTPNRDKKTDYD 1444
Query: 539 GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
E +++ + + T+R K P + + +A+ + K E + + S
Sbjct: 1445 TREYSSSKRRD--EKNELTRR----KDSPSRNKDSASGQKN---KPREERDLPKKGTGDS 1495
Query: 599 SRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESES 658
+ ++ RKP+ K + + RP E K S K+ K RE + ++
Sbjct: 1496 KKSNSSPSRDRKPHDHKATYDTKRPNEETK---SVDKNPCKDREKHVLEARNNKESSGNK 1552
Query: 659 L-----PPSSQTPKYP---ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDD 710
L PP +Q K + +++ VKP S + +E +E D
Sbjct: 1553 LLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDS 1612
Query: 711 RYPLIVK-------IDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQA---SEKV 760
+ VK I +L +I K + + + + + + + S
Sbjct: 1613 ESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSP 1672
Query: 761 SNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVP 820
S R H + + S+ K K + K HK + K+ A E +L S
Sbjct: 1673 SGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHK 1732
Query: 821 SKDPKTEHGSRKRTISQSSSLKS 843
K K K +KS
Sbjct: 1733 KKKSKKNKDKEKEKEKDDQKVKS 1755
Score = 64.7 bits (156), Expect = 5e-10
Identities = 144/742 (19%), Positives = 260/742 (35%), Gaps = 95/742 (12%)
Query: 171 SEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSS 230
++++KS SSS + + +HS+S +KEHQ +K ++ D V
Sbjct: 1035 TDNTKSSSSSQKDEKITGTPRKAHSKS------AKEHQETKPVKEEKVKKDYSKDVKSEK 1088
Query: 231 GQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPS 290
++ +KP +P+D + + + E + +S ++
Sbjct: 1089 ------------LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI--- 1133
Query: 291 SKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKT---------- 340
SK +T++ PS D +D ++ S P I +T
Sbjct: 1134 SKLEVTEIVKPSPK--RKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENI 1191
Query: 341 EPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDK 400
+K P ES S + K K + S S L D SS+ S + +K
Sbjct: 1192 SNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEK 1251
Query: 401 TMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSA 460
T + T E +N++ + D +S D + ES D ++ +P S
Sbjct: 1252 TDTKRTVIKTME--EYNNDNTAPAEDVIIMIQVPQSKWDKD-DFESEEEDVKSTQPISSV 1308
Query: 461 S-------------------PEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQG 501
PE E P+ K Q + V+ + N SS+
Sbjct: 1309 GKPASVIKNVSTKPSNIVKYPEKESEPSEKIQ--KFTKDVSHEIIQHEVKSSKNSASSEK 1366
Query: 502 YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
K + R+ S + P++ ++T + + +E G + + S S+ + RT
Sbjct: 1367 GKTKDRDY----SVLEKENPEKRKNSTQPEKESNLDRLNEQGNFK----SLSQSSKEART 1418
Query: 562 VGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSP 621
K +A P K + +T + +SS T+ P+ K+S S
Sbjct: 1419 SDKHDSTRASSNKDFTPNRDKKTDYDTR-EYSSSKRRDEKNELTRRKDSPSRNKDSASGQ 1477
Query: 622 R--PTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPS 679
+ P E+ K + S+KS D D + ++ K + N P K
Sbjct: 1478 KNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKN--PCK-- 1533
Query: 680 SVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKG 739
+ E R +LL L+ P+ +++ +T K + +P
Sbjct: 1534 --DREKHVLEARNNKESSGNKLLYILNPPE------TQVEKEQITGQIDKSTVKPKPQLS 1585
Query: 740 EKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRE 799
+ TRE + A E NE D+ ++ S K ++ S+G+ +++
Sbjct: 1586 HSSRLSSDLTRETDEAAFEP--------DYNESDSESNVSVK----EEESSGN---ISKD 1630
Query: 800 SSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSS 859
+ K K+ L + A H S + S+S S S + +S SS S
Sbjct: 1631 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQ 1690
Query: 860 STSKQKKTEGKTSSSSKEVKEK 881
+ K+KK + K + +K
Sbjct: 1691 DSKKKKKKKEKKKHKKHKKHKK 1712
Score = 35.0 bits (79), Expect = 0.42
Identities = 112/637 (17%), Positives = 216/637 (33%), Gaps = 59/637 (9%)
Query: 82 VPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSS 141
V PS K P+ ++ + + K + PA +++ + S + T S
Sbjct: 1142 VKPSPKRKMEPD--TEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSE 1199
Query: 142 SGTNSSGQRHDRESYNNSGSSSRK-KGQHGSEHS----KSRSSSPGKPQAVSSLNSSHSR 196
++S + + G RK G GS + S SS+ G P S + R
Sbjct: 1200 KLESTSSKVKQEKV---KGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKR 1256
Query: 197 S-------HGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPP-SLMSKSNS 248
+ + ND+ + + P + WD F S + +S P S + K S
Sbjct: 1257 TVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDD---FESEEEDVKSTQPISSVGKPAS 1313
Query: 249 MLQ----KPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQP 304
+++ KP+ V+ + + K+ + SH E+K S + S
Sbjct: 1314 VIKNVSTKPSNIVKYPEKESEPSEKIQ-KFTKDVSHEIIQHEVKSSKNS-------ASSE 1365
Query: 305 LDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTG-EQK 363
+ D S +++ E + P + E F ++ S+++ +
Sbjct: 1366 KGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDST 1425
Query: 364 RYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADN 423
R + +K ++ K D + SSS+ D + + T + +P N + +
Sbjct: 1426 RASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNEL--TRRKDSPSRNKDSASGQKNKPRE 1483
Query: 424 SRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQ-LDNWLNKVN 482
RD +G S S + D +A ++ + E + N + + + +
Sbjct: 1484 ERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEAR 1543
Query: 483 PHKVSPASSV--DSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS 540
+K S + + N P +Q K EQ TG T PK S + S ++
Sbjct: 1544 NNKESSGNKLLYILNPPETQVEK----EQITGQIDKSTVKPKPQLSHSSRLSSDLTRETD 1599
Query: 541 ESG--RGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
E+ +S ++S+ + + K + E+ + L + V ++ +
Sbjct: 1600 EAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSH 1659
Query: 599 SRHKAATKGSRKPN--------------IKKESKSSPRPTAEKKKYKSTSKSSQKSREII 644
S + S P+ ++SK + +KK K K
Sbjct: 1660 SSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGT 1719
Query: 645 ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSV 681
E + S + + K E + K SV
Sbjct: 1720 EVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1756
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 97.1 bits (240), Expect = 9e-20
Identities = 203/994 (20%), Positives = 368/994 (37%), Gaps = 155/994 (15%)
Query: 130 GHSSQRTSAGSSSGTNSSGQRHDRESYNNSG-SSSRKKGQHGSEHSKSRSSSPGKPQAVS 188
G+++ S++ N S +R + NS + R++ G + +SR+ P+ +S
Sbjct: 844 GYAAGAQPRPSANRENFSPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNIGSNYPEKLS 903
Query: 189 SLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNS 248
+ + + + + SKE + +P D N R G+ S P L+ S
Sbjct: 904 ARDGHNQKDNTK---SKEKESENAPGDGKGNKHKKHRKR-RKGEESEGFLNPELLETSRK 959
Query: 249 MLQKPTA---------YVRPM--DGQESMEPKLSSEH--YSSQSHGNSMTELKPSSKAHL 295
++PT +V P D + + +E + S S + KP +K
Sbjct: 960 S-REPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEKDKRERDKPKAKGDK 1018
Query: 296 TKLKIPSQPLDAS------ASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPT 349
TK K + A G VD + S PP A KT+ +K +
Sbjct: 1019 TKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDNTK---SS 1075
Query: 350 KESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGS 409
SQ+ TG ++ + ++K + ++ +K S+D E+ K P
Sbjct: 1076 SSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNE 1135
Query: 410 NSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPE---P 466
++P + E ++ G D + ESSS E ++ P P+
Sbjct: 1136 KNKPLDNKGEKRKRKTEEK----------GVDKDFESSSMKISKLEVTEIVKPSPKRKME 1185
Query: 467 PPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526
P T K +D K +PA + N ++ G++ G+ + ++T P E
Sbjct: 1186 PDTEK--MDRTPEKDKISLSAPAKKIKLN-------RETGKKIGSTENISNTKEPSEKLE 1236
Query: 527 ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586
+T S Q + GK + K G + S
Sbjct: 1237 ST------------------------SSKVKQEKVKGKVRRKVT----------GTEGSS 1262
Query: 587 ETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREII-- 644
T VD S+ ++T GS P K E K+ + T K + + ++ + ++I
Sbjct: 1263 STLVDYTST-------SSTGGS--PVRKSEEKTDTKRTVIKTMEEYNNDNTAPAEDVIIM 1313
Query: 645 -ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLS 703
+ S D D+ ES + K + + KP+SV + S + E++
Sbjct: 1314 IQVPQSKWDKDDFES---EEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKE---- 1366
Query: 704 PLSEPDDRYPLIVKIDLNLLTRIPGKPYKET-EPPKGEKKN----VPEKHTREAQKQAS- 757
SEP ++ K + + + K K + KG+ K+ V EK E +K ++
Sbjct: 1367 --SEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQ 1424
Query: 758 -EKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPA 816
EK SN + + + + SK+ +T DK+ + + SSN++ +
Sbjct: 1425 PEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDST-RASSNKDFT--------------- 1468
Query: 817 GPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEG----KTS 872
P++D KT++ +R+ + S+ K+ K++ +K+S+S K K E K
Sbjct: 1469 ---PNRDKKTDYDTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKG 1525
Query: 873 SSSKEVKEKAPSSSSNCPPSAPTLDSSKPRR-TKLVFDDRNYSADHYLQEAKKLKHNADA 931
+ + +PS T D+ +P TK V + + ++ EA+ K ++
Sbjct: 1526 TGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSG- 1584
Query: 932 LSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLA--P 989
K +Y L+ + +E + + + P P S + L + + A P
Sbjct: 1585 -----NKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEP 1639
Query: 990 DATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKT-LTEHLKNSYNNSQAPSPGLGS 1048
D +D V ES N K K + E K S + + G+
Sbjct: 1640 DYNESDSESNVSVKEEES----------SGNISKDLKDKIVEKAKESLDTAAVVQVGISR 1689
Query: 1049 KAVGMPSPVSPKLSPGNSGNYSSGASSASASGSS 1082
VSP S SG+ + SS+++S S
Sbjct: 1690 NQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAES 1723
Score = 75.9 bits (185), Expect = 2e-13
Identities = 193/979 (19%), Positives = 341/979 (34%), Gaps = 150/979 (15%)
Query: 72 PKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWT--PVG--PAPSTSQSQKRSSGL 127
P + +P P VPP P F Q G + ++ P G PAP+ + SSG+
Sbjct: 569 PHTLPLP-PGVPP-------PQFSPQFPPGQPPPAGYSVPPPGFPPAPANLSTPWVSSGV 620
Query: 128 QSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSR---------------KKGQHGSE 172
Q+ HS+ + + + R R S+ KK Q
Sbjct: 621 QTAHSNTIPTTQAPPLSREEFYREQRRLKEEEKKKSKLDEFTNDFAKELMEYKKIQKERR 680
Query: 173 HSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQR----------SKSP------RDP 216
S SRS SP + S + ++S+S S+ + R S+SP R
Sbjct: 681 RSFSRSKSPYSGSSYSRSSYTYSKSRSGSTRSRSYSRSFSRSHSRSYSRSPPYPRRGRGK 740
Query: 217 DANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYS 276
N+ S SR S G H ++S P + +S + P A+ R + P+ +E
Sbjct: 741 SRNYRSRSR---SHGYHRSRSRSPP-YRRYHSRSRSPQAF-RGQSPNKRNVPQGETE--- 792
Query: 277 SQSHGNSMTELKPSSKAHLTKLKIPSQPLDASA--SGDVSCVDEILKEMTHSWPPPLTAI 334
+ + N E+ P P D A V D KE W
Sbjct: 793 -REYFNRYREVPP--------------PYDMKAYYGRSVDFRDPFEKERYREWERKYREW 837
Query: 335 HTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSN---------------GHQSKSM 379
+ + P + + NF +R+ P N H+S+++
Sbjct: 838 YEKYYKGYAAGAQPRPSANRENF---SPERFLPLNIRNSPFTRGRREDYVGGQSHRSRNI 894
Query: 380 LKDDLKLSSSEDSDGEQDCDKTMPR---STPGSNSEPSHHNSEGADNSRDDSSSHSGSES 436
+ + S+ D ++D K+ + + PG + + + H ++S E
Sbjct: 895 GSNYPEKLSARDGHNQKDNTKSKEKESENAPG-DGKGNKHKKHRKRRKGEESEGFLNPEL 953
Query: 437 SSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNI 496
S E + + + + P +D + VS + +
Sbjct: 954 LETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMD--AESITFKSVSEKDKRERDK 1011
Query: 497 PSSQGYKKEGREQGTG-----NSYTDTSGPKETSSATPGRDSKT---IQKGSESGRGRQK 548
P ++G K + + G+ N GP+E R ++ I+K E
Sbjct: 1012 PKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKEETPKTDN 1071
Query: 549 SPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI-ESETPVDLASSMPSSRHKAATKG 607
+ + S S + G P+KA +A+E + + E + D + + S + +
Sbjct: 1072 TKSSSSSQKDEKITG--TPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEK 1129
Query: 608 SRKPNIK-----KESKSSPRPTAEKKKYKSTSKSSQKSREI-------------IETDTS 649
++KPN K + + R T EK K SS K ++ +E DT
Sbjct: 1130 AKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTE 1189
Query: 650 SSD-SDESESLPPSSQTPKYPESNRTPVKPSSVE-----EEDSFFRQRMFSPMEEKELLS 703
D + E + + S+ K + T K S E +E S + S ++++++
Sbjct: 1190 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1249
Query: 704 PLSE--PDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNV---PEKHTREAQKQASE 758
+ +D + G P +++E K+ V E++ + A +
Sbjct: 1250 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAED 1309
Query: 759 KVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSS---NRESSKQSAAK--EKDLLP 813
+ + K + D+ SE + K+ S+ KP+S N + + K EK+ P
Sbjct: 1310 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP 1369
Query: 814 SPAGPVPSKDPKTE------HGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKT 867
S +KD E S+ S+ K S E K +ST +K++
Sbjct: 1370 SEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKES 1429
Query: 868 -------EGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQ 920
+G S S+ KE S + ++ D + R K +D R YS+
Sbjct: 1430 NLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDYDTREYSSSKRRD 1489
Query: 921 EAKKLKHNADALSDRFEKA 939
E +L D+ S + A
Sbjct: 1490 EKNELTRRKDSPSRNKDSA 1508
Score = 67.4 bits (163), Expect = 8e-11
Identities = 153/803 (19%), Positives = 280/803 (34%), Gaps = 88/803 (10%)
Query: 96 EQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRES 155
++++ GS S K V PA G Q +R + S + ++
Sbjct: 1020 KRKNDGSAVSKKENIVKPA----------KGPQEKVDGERERSPRSEPPIKKAKEETPKT 1069
Query: 156 YNNSGSSSRKK-----GQHGSEHSKS-RSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQR 209
N SSS +K G HSKS + KP + +S+ ++ + + ++
Sbjct: 1070 DNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDVKSEKLTTKEEK 1129
Query: 210 SKSPRDPDANWDSPS--RVPFSSGQHSTQSFPPSLMSKSN---SMLQKPTAYVRPMDGQE 264
+K P + + D+ R + + + F S M S + + KP+ + E
Sbjct: 1130 AKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTE 1189
Query: 265 SME-----PKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASG--DVSCVD 317
M+ K+S + + N T K S +++ K PS+ L++++S
Sbjct: 1190 KMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKG 1249
Query: 318 EILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT--GEQKRYNPSKTSNGHQ 375
++ +++T + T + + P E + T + YN T+
Sbjct: 1250 KVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYNNDNTAPAED 1309
Query: 376 SKSMLKDDLKLSSSEDSDGEQ-DCDKTMPRSTPGS--------NSEPSH------HNSEG 420
M++ +D + E+ D T P S+ G +++PS+ SE
Sbjct: 1310 VIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEP 1369
Query: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNK 480
++ + + S S S+SS+ + + E E P K N
Sbjct: 1370 SEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPEKRK-------NS 1422
Query: 481 VNPHKVSPASSVDS--NIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQK 538
P K S ++ N S KE R T + + D++ TP RD KT
Sbjct: 1423 TQPEKESNLDRLNEQGNFKSLSQSSKEAR---TSDKH-DSTRASSNKDFTPNRDKKTDYD 1478
Query: 539 GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
E +++ + + T+R K P + + +A+ + K E + + S
Sbjct: 1479 TREYSSSKRRD--EKNELTRR----KDSPSRNKDSASGQKN---KPREERDLPKKGTGDS 1529
Query: 599 SRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESES 658
+ ++ RKP+ K + + RP E K S K+ K RE + ++
Sbjct: 1530 KKSNSSPSRDRKPHDHKATYDTKRPNEETK---SVDKNPCKDREKHVLEARNNKESSGNK 1586
Query: 659 L-----PPSSQTPKYP---ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDD 710
L PP +Q K + +++ VKP S + +E +E D
Sbjct: 1587 LLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHSSRLSSDLTRETDEAAFEPDYNESDS 1646
Query: 711 RYPLIVK-------IDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQA---SEKV 760
+ VK I +L +I K + + + + + + + S
Sbjct: 1647 ESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSP 1706
Query: 761 SNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVP 820
S R H + + S+ K K + K HK + K+ A E +L S
Sbjct: 1707 SGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHK 1766
Query: 821 SKDPKTEHGSRKRTISQSSSLKS 843
K K K +KS
Sbjct: 1767 KKKSKKNKDKEKEKEKDDQKVKS 1789
Score = 64.7 bits (156), Expect = 5e-10
Identities = 144/742 (19%), Positives = 260/742 (35%), Gaps = 95/742 (12%)
Query: 171 SEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSS 230
++++KS SSS + + +HS+S +KEHQ +K ++ D V
Sbjct: 1069 TDNTKSSSSSQKDEKITGTPRKAHSKS------AKEHQETKPVKEEKVKKDYSKDVKSEK 1122
Query: 231 GQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPS 290
++ +KP +P+D + + + E + +S ++
Sbjct: 1123 ------------LTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMKI--- 1167
Query: 291 SKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKT---------- 340
SK +T++ PS D +D ++ S P I +T
Sbjct: 1168 SKLEVTEIVKPSPK--RKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENI 1225
Query: 341 EPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDK 400
+K P ES S + K K + S S L D SS+ S + +K
Sbjct: 1226 SNTKEPSEKLESTSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEK 1285
Query: 401 TMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSA 460
T + T E +N++ + D +S D + ES D ++ +P S
Sbjct: 1286 TDTKRTVIKTME--EYNNDNTAPAEDVIIMIQVPQSKWDKD-DFESEEEDVKSTQPISSV 1342
Query: 461 S-------------------PEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQG 501
PE E P+ K Q + V+ + N SS+
Sbjct: 1343 GKPASVIKNVSTKPSNIVKYPEKESEPSEKIQ--KFTKDVSHEIIQHEVKSSKNSASSEK 1400
Query: 502 YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
K + R+ S + P++ ++T + + +E G + + S S+ + RT
Sbjct: 1401 GKTKDRDY----SVLEKENPEKRKNSTQPEKESNLDRLNEQGNFK----SLSQSSKEART 1452
Query: 562 VGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSP 621
K +A P K + +T + +SS T+ P+ K+S S
Sbjct: 1453 SDKHDSTRASSNKDFTPNRDKKTDYDTR-EYSSSKRRDEKNELTRRKDSPSRNKDSASGQ 1511
Query: 622 R--PTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPS 679
+ P E+ K + S+KS D D + ++ K + N P K
Sbjct: 1512 KNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKN--PCK-- 1567
Query: 680 SVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKG 739
+ E R +LL L+ P+ +++ +T K + +P
Sbjct: 1568 --DREKHVLEARNNKESSGNKLLYILNPPE------TQVEKEQITGQIDKSTVKPKPQLS 1619
Query: 740 EKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRE 799
+ TRE + A E NE D+ ++ S K ++ S+G+ +++
Sbjct: 1620 HSSRLSSDLTRETDEAAFEP--------DYNESDSESNVSVK----EEESSGN---ISKD 1664
Query: 800 SSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSS 859
+ K K+ L + A H S + S+S S S + +S SS S
Sbjct: 1665 LKDKIVEKAKESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASSAESQ 1724
Query: 860 STSKQKKTEGKTSSSSKEVKEK 881
+ K+KK + K + +K
Sbjct: 1725 DSKKKKKKKEKKKHKKHKKHKK 1746
Score = 35.0 bits (79), Expect = 0.42
Identities = 112/637 (17%), Positives = 216/637 (33%), Gaps = 59/637 (9%)
Query: 82 VPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSS 141
V PS K P+ ++ + + K + PA +++ + S + T S
Sbjct: 1176 VKPSPKRKMEPD--TEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSE 1233
Query: 142 SGTNSSGQRHDRESYNNSGSSSRK-KGQHGSEHS----KSRSSSPGKPQAVSSLNSSHSR 196
++S + + G RK G GS + S SS+ G P S + R
Sbjct: 1234 KLESTSSKVKQEKV---KGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKR 1290
Query: 197 S-------HGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPP-SLMSKSNS 248
+ + ND+ + + P + WD F S + +S P S + K S
Sbjct: 1291 TVIKTMEEYNNDNTAPAEDVIIMIQVPQSKWDKDD---FESEEEDVKSTQPISSVGKPAS 1347
Query: 249 MLQ----KPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQP 304
+++ KP+ V+ + + K+ + SH E+K S + S
Sbjct: 1348 VIKNVSTKPSNIVKYPEKESEPSEKIQ-KFTKDVSHEIIQHEVKSSKNS-------ASSE 1399
Query: 305 LDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTG-EQK 363
+ D S +++ E + P + E F ++ S+++ +
Sbjct: 1400 KGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDST 1459
Query: 364 RYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADN 423
R + +K ++ K D + SSS+ D + + T + +P N + +
Sbjct: 1460 RASSNKDFTPNRDKKTDYDTREYSSSKRRDEKNEL--TRRKDSPSRNKDSASGQKNKPRE 1517
Query: 424 SRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQ-LDNWLNKVN 482
RD +G S S + D +A ++ + E + N + + + +
Sbjct: 1518 ERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEAR 1577
Query: 483 PHKVSPASSV--DSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS 540
+K S + + N P +Q K EQ TG T PK S + S ++
Sbjct: 1578 NNKESSGNKLLYILNPPETQVEK----EQITGQIDKSTVKPKPQLSHSSRLSSDLTRETD 1633
Query: 541 ESG--RGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
E+ +S ++S+ + + K + E+ + L + V ++ +
Sbjct: 1634 EAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSH 1693
Query: 599 SRHKAATKGSRKPN--------------IKKESKSSPRPTAEKKKYKSTSKSSQKSREII 644
S + S P+ ++SK + +KK K K
Sbjct: 1694 SSPSVSPSRSHSPSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGT 1753
Query: 645 ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSV 681
E + S + + K E + K SV
Sbjct: 1754 EVELEKSQKHKHKKKKSKKNKDKEKEKEKDDQKVKSV 1790
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 92.4 bits (228), Expect = 2e-18
Identities = 189/891 (21%), Positives = 295/891 (33%), Gaps = 144/891 (16%)
Query: 86 ADEKSNPNFFEQRHGGS----HQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSS 141
AD + +++ GS HQ S + + S +R SG S+ R GSS
Sbjct: 1244 ADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSG-----SASRNHHGSS 1298
Query: 142 SGTNSSGQRH------DRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHS 195
+ G RH DR S+ +S SSR+ G H +E S + QA SS H
Sbjct: 1299 REQSRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHG 1358
Query: 196 RSHGNDHHSKEH------QRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMS--KSN 247
H S H Q S + RD S S+V S G HS S S+ + ++
Sbjct: 1359 SRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSGSQVTNSEG-HSEDSDTQSVSAHGQAG 1417
Query: 248 SMLQKPTAYVRPMDGQESMEPK-----LSSEHYSSQSHG----------NSMTELKPSSK 292
Q R G+ S + +SS S +HG S E +S
Sbjct: 1418 PHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSS 1477
Query: 293 AHLTKL----KIPSQPLDASASGDVSCVDEILKEMTHS------WPPPLTAIHTPCKTEP 342
H I P + S ++ + HS P + + ++ P
Sbjct: 1478 RHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGP 1537
Query: 343 SKFPFPTKESQQSNFGT--GEQKRYNPSKTSNGHQ-----------SKSMLKDDLKLSSS 389
T+ +QS G+ + + PS + + SK+ + +S
Sbjct: 1538 RSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQD 1597
Query: 390 EDSDGEQD----CDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGS-ESSSGSDSES 444
DS+G + ++ R+ GS E S H S + ++D +SH S ESS S +
Sbjct: 1598 RDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRH 1657
Query: 445 ESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYK- 503
+SS +A + A P ++ H+ S SS DS Q
Sbjct: 1658 AETSSGGQAASSQEQARSSPGERHGSR------------HQQSADSSTDSGTGRRQDSSV 1705
Query: 504 --KEGREQGTGNSYTDTSGPKETSS----ATPGRDSKTIQKGSESGRGRQKSPAQSDSTT 557
G +G+ +D+ G E S + G+ Q ES RG+ + +
Sbjct: 1706 VGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSF 1765
Query: 558 QRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKES 617
+ +Q + A G + E D SSRH A+ +G + +
Sbjct: 1766 LYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARD------SSRHSASQEGQ---DTIRGH 1816
Query: 618 KSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVK 677
S R + Y+ + SS S TS SD S S + + K
Sbjct: 1817 PGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNE----K 1872
Query: 678 PSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPP 737
S S R S + S + + P
Sbjct: 1873 QSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGP---------------------RTS 1911
Query: 738 KGEKKNVPEKHTREAQKQASEKVSNKGKRKHKN---EDDNRASESKKPKTEDKNSAGHKP 794
+ + +V + + + SE+ S R H E S ED+ GH
Sbjct: 1912 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSA 1971
Query: 795 SSNRE--------SSKQSAAKEKDLLPSPAG-------PVPSKDPKTE----HGSRKRTI 835
S+R+ SS+ AA + S AG + S D HG +
Sbjct: 1972 DSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASSAV 2031
Query: 836 SQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSS 886
S S + ++ G S++S + S +GK + KE A S
Sbjct: 2032 RDSGHRGYSGSQASDSEGHSEDSDTQS--VSAQGKAGPHQQSHKESARGQS 2080
Score = 86.3 bits (212), Expect = 2e-16
Identities = 178/833 (21%), Positives = 283/833 (33%), Gaps = 91/833 (10%)
Query: 101 GSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRH------DRE 154
GS S + S S+ S SG S+ R GS+ + G RH DR
Sbjct: 935 GSRTSRRQGSSVSQDSDSEGHSEDSERWSG-SASRNHRGSAQEQSRHGSRHPRSHHEDRA 993
Query: 155 SYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEH------Q 208
+ +S SSR+ G +E S ++ QA SS H H S H Q
Sbjct: 994 GHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQ 1053
Query: 209 RSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMS--KSNSMLQKPTAYVRPMDGQESM 266
S + RD +W S S HS +S S+ + Q R G S
Sbjct: 1054 ASSAVRD-SGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSG 1112
Query: 267 EP-----KLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILK 321
++S+ S +HG + T +H + + S+ AS G + ++
Sbjct: 1113 RSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRH-SASQEGQ-----DTIR 1166
Query: 322 EMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLK 381
S H +QS +G ++ TS G S +
Sbjct: 1167 AHPGSRRGGRQGSH----------------HEQSVDRSGHSGSHHSHTTSQGRSDASHGQ 1210
Query: 382 DDLKLSSSEDSDGEQDCDKTMPRST----PGSNSEPSHHNSEGADNSRDDSSS-HSGSES 436
+ +S + +Q D + + S ++ S H+ G + S +S H GS
Sbjct: 1211 SGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSV 1270
Query: 437 SSGSDSESESSSSD-----------SEANEPSQSASPEP----EPPPTNKWQLDNWLNKV 481
S SDSE S S+ + E S+ S P E ++ D+
Sbjct: 1271 SQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSG 1330
Query: 482 NPHKVSP----ASSVDSNIPSSQGYKKEGREQGTGNSYTDTS-GPKETSSATPGRDSKTI 536
H S A S SS G + R Q + +S + G ++ SSA RDS
Sbjct: 1331 THHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAV--RDSG-- 1386
Query: 537 QKGSESGRGRQKSPAQSDSTTQRRTV-GKKQPKKAEKAAAEEPRGGLKIESETPVDLASS 595
+GS + DS TQ + G+ P +++ E RG S
Sbjct: 1387 HRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPH--QQSHKESARGQSGESSGRSRSFLYQ 1444
Query: 596 MPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDE 655
+ S +T G P+ S E+ + S +SQ ++ I SS
Sbjct: 1445 VSSHEQSESTHGQTAPSTGGRQGSRH----EQARNSSRHSASQDGQDTIRGHPGSSRGGR 1500
Query: 656 SESLPPSSQTPK----YPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDR 711
S S Y S+ TP S S R E++ R
Sbjct: 1501 QGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSR 1560
Query: 712 Y-PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKH-- 768
+ + + +++ ++ + + +V + E + SE+ S R H
Sbjct: 1561 HHEPSTRAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYG 1620
Query: 769 -KNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTE 827
E S + + ED+ S GH S+R+S + A + + P
Sbjct: 1621 SAREQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER 1680
Query: 828 HGSRKRTISQSSSLKSSSNSNKETS---GSSKNSSSTSKQKKTEGKTSSSSKE 877
HGSR + S SS S + +++S S SS S+ +EG + S +
Sbjct: 1681 HGSRHQQ-SADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQ 1732
Score = 80.5 bits (197), Expect = 9e-15
Identities = 175/852 (20%), Positives = 294/852 (34%), Gaps = 88/852 (10%)
Query: 85 SADEKSNPNFFEQRHGGSHQ------------SSKWTPVGPAPSTSQSQKRSSGLQSGHS 132
S+D KS+ RH + Q S+ + + S+ +R SG S
Sbjct: 262 SSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSG-----S 316
Query: 133 SQRTSAGSSSGTNSSGQRH------DRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQA 186
+ R GS+ + G RH DR S+ +S SSR+ G +E S ++ QA
Sbjct: 317 ASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQA 376
Query: 187 VSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKS 246
SS H H S H + + A D R SSG ++ S S S +
Sbjct: 377 RSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHRG--SSGSQASDSEGHSENSDT 434
Query: 247 NSMLQKPTAYVRPMDGQESMEPK--------------LSSEHYSSQSHGNSMTELKPSSK 292
S+ A +R QES + +S+ +HG + T
Sbjct: 435 QSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQG 494
Query: 293 AHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKES 352
+H + + S+ AS G ++ P E S S
Sbjct: 495 SHHEQARDSSRH-SASQEG---------QDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGS 544
Query: 353 QQSNFGTGEQKRYNPSKTSNGHQSKSMLK-------DDLKLSSSEDSDGEQDCDKTMPRS 405
S+ T Q R + S +G +S S D + S S + D +
Sbjct: 545 HHSH--TTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQ 602
Query: 406 T-PGSNSEPSHHNSEGADNSRD-DSSSHS-GSESSSGSDSESESSSSDSEANEPSQSASP 462
G +S P ++G+ S+D DS HS SE SGS S + S+ ++ + S+
Sbjct: 603 VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRS 662
Query: 463 EPEPPPTNKWQLDNWLNKVNPHKVSPAS----SVDSNIPSSQGYKKEGREQGTGNSYTDT 518
E + D+ H + +S S SS G + R Q +
Sbjct: 663 HHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRH 722
Query: 519 SGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEP 578
SG +++ RDS +GS + DS TQ + G Q +++ E
Sbjct: 723 SGTGHGQASSAVRDSG--HRGSSGSQATDSEGHSEDSDTQSVS-GHGQAGHHQQSHQESA 779
Query: 579 RGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQ 638
R S + + + ++ G P+ S E+ + S +SQ
Sbjct: 780 RDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHH----EQARDNSRHSASQ 835
Query: 639 KSREIIETDTSSS-----DSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMF 693
++ I SS S +S+ S + + S+ T S S R
Sbjct: 836 DGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSH-HSHTTSQGRSDASRGQSGSRSASR 894
Query: 694 SPMEEKELLSPLSEPDDRY-PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREA 752
+ E++ R+ D++ ++ + + + + +V + E
Sbjct: 895 TTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEG 954
Query: 753 QKQASEKVSNKGKRKHKN---EDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEK 809
+ SE+ S R H+ E S + ED+ GH S+R+S A
Sbjct: 955 HSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSS 1014
Query: 810 DLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNS----SSTSKQK 865
+ + P HGSR + + SS + S ++ S + ++S SS S+
Sbjct: 1015 GGQAASSHEQARSSPGERHGSRHQQSADSS--RHSGIPRRQASSAVRDSGHWGSSGSQAS 1072
Query: 866 KTEGKTSSSSKE 877
+EG + S +
Sbjct: 1073 DSEGHSEESDTQ 1084
Score = 80.5 bits (197), Expect = 9e-15
Identities = 183/899 (20%), Positives = 311/899 (34%), Gaps = 120/899 (13%)
Query: 97 QRHGGSHQ-----SSKWTPVGPAPSTS----QSQKRSSGLQSGHS---SQRTSAGSSSGT 144
+RHG HQ SS+ + G ++S + SSG Q+ S S+ + S SG
Sbjct: 706 ERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGH 765
Query: 145 NSSG---QRHDRESYNNSGSSSRKKGQ---HGSEHSKSRSSSPGK-PQAVSSLNSSHSRS 197
+G Q H + + SG SR+ G S H +S SS P S H ++
Sbjct: 766 GQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQA 825
Query: 198 HGNDHHSKEHQ----------RSKSPRDPDANWDSPSRVPFSSGQHS-TQSFPPSLMSKS 246
N HS S+ R + S R S HS T S S S+
Sbjct: 826 RDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRG 885
Query: 247 NSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGN----SMTELKPSSKAHLTKLKIPS 302
S + + R + S H+ + SH + S S + ++ + S
Sbjct: 886 QSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSS 945
Query: 303 QPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQ 362
D+ + G E + W + H E QS G+
Sbjct: 946 VSQDSDSEGH--------SEDSERWSGSASRNHRGSAQE------------QSRHGSRHP 985
Query: 363 KRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGAD 422
+ ++ + +GH + S + + + S G+ RS+PG H S AD
Sbjct: 986 RSHHEDRAGHGHSADSSRQSGTPHAETS-SGGQAASSHEQARSSPGERHGSRHQQS--AD 1042
Query: 423 NSRDDS------------SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTN 470
+SR S H GS S SDSE S SD+++ P + ++
Sbjct: 1043 SSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQ---SH 1099
Query: 471 KWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKK----EGREQGTGNSYTDTSGPKETSS 526
+ +W + S V ++ S + + GR QG+ + S S+
Sbjct: 1100 QESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDS--SRHSA 1157
Query: 527 ATPGRDSKTIQKGSESGRGRQKSPAQS--DSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI 584
+ G+D+ GS G GRQ S + D + + + A+ G
Sbjct: 1158 SQEGQDTIRAHPGSRRG-GRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSA 1216
Query: 585 ESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREII 644
+T D S SRH GSR + SS +++ + S + +
Sbjct: 1217 SRQTRKDKQSG-DGSRH----SGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVS 1271
Query: 645 ETDTSSSDSDESESLPPSSQTPKY---PESNRTPVKPSSVEEEDSFFRQRMFSPMEEKEL 701
+ S SD+SE L S+ + E +R + +ED S ++
Sbjct: 1272 QDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDR--ASHGHSADSSRQS 1329
Query: 702 LSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVS 761
+ +E + + PG E + ++ +H+ +QAS V
Sbjct: 1330 GTHHTESSSHGQAVSSHE--QARSSPG----ERHGSRHQQSADSSRHSGIGHRQASSAVR 1383
Query: 762 NKGKR----KHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSK----QSAAKEKDLLP 813
+ G R + + +S AG S++ES++ +S+ + + L
Sbjct: 1384 DSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLY 1443
Query: 814 SPAGPVPSKD------PKT--EHGSRKRTISQSSSLKSSSNSNKET----SGSSKNSSST 861
+ S+ P T GSR +++SS S+S ++T GSS+
Sbjct: 1444 QVSSHEQSESTHGQTAPSTGGRQGSRHEQ-ARNSSRHSASQDGQDTIRGHPGSSRGGRQG 1502
Query: 862 SKQKKTEGKTSSSSKEVKEKAPSSSSNCP--PSAPTLDSSKPRRTKLVFDDRNYSADHY 918
S +++ ++ S P S+ S P S + R + D +S +
Sbjct: 1503 SYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRH 1561
Score = 77.8 bits (190), Expect = 6e-14
Identities = 172/846 (20%), Positives = 296/846 (34%), Gaps = 132/846 (15%)
Query: 98 RHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSA--GSSSGTNSSGQRHDRES 155
RH GSH A S + S + S Q S RTS GSS +S + H +S
Sbjct: 2204 RHSGSHHHE-------ASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDS 2256
Query: 156 YNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRD 215
SGS+SR HGS +SR S H RSH D H S +
Sbjct: 2257 ERRSGSASRN--HHGSAQEQSRDGS------------RHPRSHHEDRAGHGHSAESSRQ- 2301
Query: 216 PDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHY 275
SG H ++ + S+ + Q+S + S +
Sbjct: 2302 --------------SGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSAD----SSRH 2343
Query: 276 SSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIH 335
S HG + + ++ S + SQ D+ + S + H P H
Sbjct: 2344 SGIGHGQASSAVRDSGHRGSSG----SQASDSEGHSEDSDTQSV---SAHGQAGP----H 2392
Query: 336 TPCKTEPSKFPFPTKESQQSNF----GTGEQKR--YNPSKTSNGHQSKSMLKDDLKLSSS 389
E ++ + + +F T EQ + + TS G + S K S
Sbjct: 2393 QQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRH 2452
Query: 390 EDSDGEQDCDKTMPRSTPG-------------SNSEPSHHNSEGADNSRDDSSSHSGSES 436
S QD P S+ G S SHH+ + D S HSGS S
Sbjct: 2453 STSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRS 2512
Query: 437 SS--------------GSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVN 482
+S S S +SS ++++ SQ + E P T++ NW + +
Sbjct: 2513 ASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSR----NWGSSFS 2568
Query: 483 PHKVSPASSVDS---NIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKG 539
S S DS + +S+ + +EQ S S ++ + DS Q G
Sbjct: 2569 QDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSR-QSG 2627
Query: 540 SESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSS 599
+ + A S R + G++ +++A G+ +S++ S
Sbjct: 2628 TRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGI-----GHGQASSAVRDS 2682
Query: 600 RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESL 659
H+ + N S + + + S +S Q+S S S S S
Sbjct: 2683 GHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESAR----GRSGETSGHSGSF 2738
Query: 660 PPSSQTPKYPESNRTPVKPSSVEEEDSFFRQ-----RMFSPMEEKELL--SPLSEPDDR- 711
T + ES+ PS+ + S Q R + + ++ + P S R
Sbjct: 2739 LYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQ 2798
Query: 712 -YPLIVKIDLNLLTRIPGKPYKET------EPPKGEKKNVPEKHTREAQKQASEKVSNKG 764
Y +D + G + T + +G+ + T ++Q+ + + G
Sbjct: 2799 GYHHEHSVD---SSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSG 2855
Query: 765 KRKHK---NEDDNRASESKKPKTEDKNSAGHKPSS-NRESSKQSAAKEKDLLPSPAGPVP 820
R H+ + D +R S++ + ++E + + SS +++S + +++ + A
Sbjct: 2856 SRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSAS--- 2912
Query: 821 SKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKE 880
+ HGS + + S S ++ G S +SS S + T+ + + E
Sbjct: 2913 ----RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHE 2968
Query: 881 KAPSSS 886
+A SS+
Sbjct: 2969 QARSSA 2974
Score = 72.8 bits (177), Expect = 2e-12
Identities = 166/864 (19%), Positives = 284/864 (32%), Gaps = 122/864 (14%)
Query: 86 ADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTN 145
AD + + + G S W S SQ S SG S+ R GS+
Sbjct: 2541 ADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSG-SASRNHHGSAQEQL 2599
Query: 146 SSGQRH------DRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHG 199
G RH DR + +S SSR Q G+ H+++ S QA SS +RS
Sbjct: 2600 RDGSRHPRSHQEDRAGHGHSADSSR---QSGTRHTQTSSGG----QAASS--HEQARSSA 2650
Query: 200 NDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRP 259
+ H HQ+S DS GQ S+ S S +
Sbjct: 2651 GERHGSHHQQSA---------DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSED 2701
Query: 260 MDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEI 319
D Q + H QSH S + H S VS ++
Sbjct: 2702 SDTQSVSAHGQAGSH--QQSHQESARGRSGETSGH-----------SGSFLYQVSTHEQ- 2747
Query: 320 LKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQ----------SNFGTGEQKRYNPSK 369
E +H W P T + E ++ SQ S+ G + + S
Sbjct: 2748 -SESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSV 2806
Query: 370 TSNGHQSK--SMLKDDLKLSSSEDSDGEQDCDKTM---PRSTPGSNSEPSHHN--SEGAD 422
S+GH S + +S G + +T +S GS S H+ S AD
Sbjct: 2807 DSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHAD 2866
Query: 423 NSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVN 482
SR + SE S S + S S DS++ S+ + + W +
Sbjct: 2867 ISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDS--------------ERWSGSAS 2912
Query: 483 -PHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSE 541
H S + + ++++ G + SG + T +++ G+ + + ++
Sbjct: 2913 RNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARS 2972
Query: 542 SGRGRQKSPAQSDSTTQRRT-VGKKQPKKAEKAAAEEPRGGLKI--------ESETPVDL 592
S R S Q + + R + +G Q A + + G + +S+T
Sbjct: 2973 SAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVS 3032
Query: 593 ASSMPSSRHKAATKGSR---------------KPNIKKESKSSPRPTA-----------E 626
A S ++ + +R + + ++S+SS T E
Sbjct: 3033 AHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHE 3092
Query: 627 KKKYKSTSKSSQKSREIIETDTSSSDS-----DESESLPPSSQTPKYPESNRTPVKPSSV 681
+ + S +SQ ++ I SS S+ S + + + + +
Sbjct: 3093 QAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 3152
Query: 682 EEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEK 741
+ + EE+ S + D++ ++ + + + +
Sbjct: 3153 RGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 3212
Query: 742 KNVPEKHTREAQKQASEKVSNKGKRKHK---NEDDNRASESKKPKTEDKNSAGHKPSSNR 798
+V + E + SE+ S R H+ E S + ED+ GH +R
Sbjct: 3213 SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSR 3272
Query: 799 ESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSS-------SLKSSSNSNKET 851
+S + A + + P HGSR + + SS SS+ +
Sbjct: 3273 QSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRH 3332
Query: 852 SGSSKNSSSTSKQKKTEGKTSSSS 875
GSS + +S S+ E T S S
Sbjct: 3333 WGSSGSQASDSEGHSEESDTQSVS 3356
Score = 72.8 bits (177), Expect = 2e-12
Identities = 166/840 (19%), Positives = 277/840 (32%), Gaps = 102/840 (12%)
Query: 98 RHGGSHQSSKWTPVGPAPSTSQSQKR----SSGLQ--SGHSSQRTSAGSSSGTN----SS 147
RH SHQ + A S+ QS R SSG Q S H R+SAG G++ +
Sbjct: 2928 RHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSAD 2987
Query: 148 GQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEH 207
RH + + S+ R G G S++ + + + S+H ++ H + H
Sbjct: 2988 SSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGS---HQQSH 3044
Query: 208 QRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESME 267
Q S R + +SG + + S +S S R G +
Sbjct: 3045 QESARGRSGE-----------TSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQ 3093
Query: 268 PKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASA---SGDVSCVDEILKEMT 324
+ SS H +SQ +G P S + +D+S S + + +
Sbjct: 3094 AQDSSRHSASQ-YGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 3152
Query: 325 HSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT-GEQKRYNPSKTSNGHQSKSMLKDD 383
+A T E S S+ T + R++ + S+ +
Sbjct: 3153 RGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQG 3212
Query: 384 LKLSSSEDSDGEQDCDK----TMPRSTPGSNSEPSHHNSEGADNSRDDSSSH--SGSESS 437
+S DS+G + + + R+ GS E S H S + +D + H S S
Sbjct: 3213 SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSR 3272
Query: 438 SGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIP 497
+E+SS A+ Q+ S E + H+ S SS S IP
Sbjct: 3273 QSGTRHAETSSGGQAASSHEQARSSPGERHGSR-------------HQQSADSSRHSGIP 3319
Query: 498 SSQGYK--KEGREQGT-GNSYTDTSGPKETSSATP----GRDSKTIQKGSESGRGRQ--K 548
Q ++ R G+ G+ +D+ G E S G+ Q ES R R +
Sbjct: 3320 RGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGR 3379
Query: 549 SPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS 608
S Q T + + + R G E + SSRH A+ +G
Sbjct: 3380 SGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQ--------ARDSSRHSASQEG- 3430
Query: 609 RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKY 668
+ I+ SS R +S +S T TS SD S S +
Sbjct: 3431 -QDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHT-TSQGRSDASRGQSGSRSASRQ 3488
Query: 669 PESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPG 728
++ + S S+ S + S + P
Sbjct: 3489 TRND----EQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGP--------------- 3529
Query: 729 KPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKT---E 785
+ + +V + + + SE+ S R H+ ++ + + T E
Sbjct: 3530 ------RTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHE 3583
Query: 786 DKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSS 845
D+ GH S+R+S A S G S + + +R S SS
Sbjct: 3584 DRAGHGHSAESSRQSGTHHAEN------SSGGQAASSHEQARSSAGERHGSHHQQSADSS 3637
Query: 846 NSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTK 905
+ G + ++ S + + G +S S+ E + + S + A S T+
Sbjct: 3638 RHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTR 3697
Score = 72.4 bits (176), Expect = 2e-12
Identities = 164/827 (19%), Positives = 288/827 (34%), Gaps = 95/827 (11%)
Query: 95 FEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRE 154
+E+ +SS +TSQ + S + S+ + S G + +RH
Sbjct: 257 YERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERH--- 313
Query: 155 SYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPR 214
SGS+SR HGS +SR S H RSH D S H S +
Sbjct: 314 ----SGSASR--NHHGSAWEQSRD------------GSRHPRSHDEDRASHGHSADSSRQ 355
Query: 215 DPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEH 274
+ ++ SR +S +S P + + + GQ +S
Sbjct: 356 SGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQ-------ASSA 408
Query: 275 YSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAI 334
S + H S S+ H S S G + +E T +
Sbjct: 409 VSDRGHRGSSGSQASDSEGHSEN----SDTQSVSGHGKAGLRQQSHQESTRGRSGERSGR 464
Query: 335 HTPCKTEPSKFPFPTKESQQSNFGTG--EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDS 392
+ S P ++ TG + + ++ S+ H + +D ++
Sbjct: 465 SGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSR 524
Query: 393 DGEQDCDKTMPRSTPG-SNSEPSHHNSEG-ADNSRDDSSSHSGS-----ESSSG-----S 440
G Q + G S S SH S+G +D S S S S S E SG S
Sbjct: 525 GGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHS 584
Query: 441 DSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDS---NIP 497
S +SS ++++ SQ + P T++ N + V+ S S DS +
Sbjct: 585 GSRHHEASSQADSSRHSQVGQGQSSGPRTSR----NQGSSVSQDSDSQGHSEDSERWSGS 640
Query: 498 SSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTT 557
+S+ + +EQ S S ++ + DS + G+ + A S
Sbjct: 641 ASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSR-KSGTRHTQNSSSGQAASSHEQ 699
Query: 558 QRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKES 617
R + G++ + + +A+ R S T ASS + GS+ + + S
Sbjct: 700 ARSSAGERHGSRHQLQSADSSR-----HSGTGHGQASSAVRDSGHRGSSGSQATDSEGHS 754
Query: 618 KSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVK 677
+ S + + Q+S + D S S S S T K ES+
Sbjct: 755 EDS---DTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTG 811
Query: 678 PSSVEEEDSFFRQ-----RMFSPMEEKELL--SPLSEPDDRYPLIVKIDLNLLTRIPGKP 730
PS+ + S Q R + + ++ + P S R + ++ + G
Sbjct: 812 PSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVD-RSGHSGSH 870
Query: 731 YKET------EPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK---NEDDNRASESKK 781
+ T + +G+ + T ++Q+ + + G R H+ + D +R S++ +
Sbjct: 871 HSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQ 930
Query: 782 PKTE--------------DKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTE 827
++E D +S GH S R S SA++ S+ P++
Sbjct: 931 GQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSG--SASRNHRGSAQEQSRHGSRHPRSH 988
Query: 828 HGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSS 874
H R + S + S + ETS + +SS + + + G+ S
Sbjct: 989 HEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGS 1035
Score = 70.5 bits (171), Expect = 9e-12
Identities = 157/862 (18%), Positives = 296/862 (34%), Gaps = 103/862 (11%)
Query: 98 RHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYN 157
RH GS T G + + Q S+G ++ S+R + S +S G D E +
Sbjct: 1555 RHSGSRHHEPSTRAGSSRHSQVGQGESAGSKT---SRRQGSSVSQDRDSEGHSEDSERRS 1611
Query: 158 NSGS-----SSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKS 212
S S S+R++ +HGS + +S S +S+ S H++ ++
Sbjct: 1612 ESASRNHYGSAREQSRHGSRNPRSHQED-----RASHGHSAESSRQSGTRHAETSSGGQA 1666
Query: 213 PRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSS 272
+ SP S Q S S S + + R G ++ + + S
Sbjct: 1667 ASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHS 1726
Query: 273 EHYSSQS---HGNSMTELKPSSKAHLTKLKIPSQPLDASASG---DVSCVDEILKEMTHS 326
E +QS HG + P ++H + S + VS ++ E H
Sbjct: 1727 EESDTQSVSAHGQA----GPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQ--SESAHG 1780
Query: 327 WPPPLTAIHTPCKTEPSKFPFPTKESQQ----------SNFGTGEQKRYNPSKTSNGHQS 376
P T + E ++ SQ+ S+ G + Y S S+GH
Sbjct: 1781 RTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSG 1840
Query: 377 KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSES 436
S + ++ D + +S S S + + + D SR S H E+
Sbjct: 1841 ----------SHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHH--EA 1888
Query: 437 SSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQ-----LDNWLNKVNPHKVSPASS 491
SS +DS S +++ P S + + Q + W + + + A
Sbjct: 1889 SSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWE 1948
Query: 492 VDSNIPSSQGYKKEGREQGTGNSYTDT--SGPKETSSATPGRDSKTIQKGSESGRGRQKS 549
+ G E R G G+S + SG + T S++ G+ + + ++ S R S
Sbjct: 1949 QSRDGSRHPGSHHEDRA-GHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGS 2007
Query: 550 --PAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKG 607
QS +++ +G Q A + + G S+ S S + +G
Sbjct: 2008 HHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSG----SQASDSEGHSEDSDTQSVSAQG 2063
Query: 608 SRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPK 667
P+ + S + +A + +S+ +S ++ + S S +S Q
Sbjct: 2064 KAGPH-----QQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSH 2118
Query: 668 YPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIP 727
Y ++ + +S E +D+ P R
Sbjct: 2119 YDQAQDSSRHSASQEGQDTIRGH-------------PGPSRGGRQ--------------- 2150
Query: 728 GKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDK 787
G +++ G + T + + AS S K D ++ + +
Sbjct: 2151 GSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHH 2210
Query: 788 NSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTE-HGSRKRTISQSSSLKSSSN 846
+ A S+R S P G S+D +E H S S+S +
Sbjct: 2211 HEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGS 2270
Query: 847 SNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKL 906
+ +++ S++ S + + G ++ SS++ S + + S+ +S + +
Sbjct: 2271 AQEQSRDGSRHPRSHHEDRAGHGHSAESSRQ------SGTHHAENSSGGQAASSHEQARS 2324
Query: 907 VFDDRNYSADHYLQEAKKLKHN 928
+R+ S H+ Q A +H+
Sbjct: 2325 SAGERHGS--HHQQSADSSRHS 2344
Score = 70.1 bits (170), Expect = 1e-11
Identities = 180/877 (20%), Positives = 291/877 (33%), Gaps = 143/877 (16%)
Query: 67 GDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSG 126
G RS+ + K + S S + R S S P TS++Q S
Sbjct: 1860 GSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVS 1919
Query: 127 LQS---GHS---------SQRTSAGSSSGTNSSGQRH------DRESYNNSGSSSRK--- 165
S GHS + R GS+ + G RH DR + +S SSR+
Sbjct: 1920 QDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGT 1979
Query: 166 -------KGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDA 218
+GQ S H ++RSS+ + + L S+ S H H Q S + RD
Sbjct: 1980 RHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHG---QASSAVRDSGH 2036
Query: 219 NWDSPSRVPFSSGQHSTQSFPPSL--MSKSNSMLQKPTAYVRPMDGQESMEP-----KLS 271
S S+ S G HS S S+ K+ Q R G+ S ++S
Sbjct: 2037 RGYSGSQASDSEG-HSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVS 2095
Query: 272 SEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPL 331
+ S +HG S +H + + S+ AS G ++ P
Sbjct: 2096 THEQSESTHGQSAPSTGGRQGSHYDQAQDSSRH-SASQEG---------QDTIRGHP--- 2142
Query: 332 TAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSED 391
PS+ +QS +G ++ TS G S + + +S +
Sbjct: 2143 ---------GPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKT 2193
Query: 392 SDGEQDCDKTMPRSTPGSNSEPSHHN--SEGADNSRDDSSSHSGSE---------SSSGS 440
D EQ D GS SHH+ S AD+SR S SS
Sbjct: 2194 YDKEQSGD--------GSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQ 2245
Query: 441 DSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVD-SNIPSS 499
DS+SE S DSE S S N H + S D S P S
Sbjct: 2246 DSDSEGHSEDSERRSGSASR---------------------NHHGSAQEQSRDGSRHPRS 2284
Query: 500 QGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR 559
+ G +S + E SS S Q S +G QS +++
Sbjct: 2285 HHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE-QARSSAGERHGSHHQQSADSSRH 2343
Query: 560 RTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKS 619
+G Q A + + G S+ S S + G P+ + +S
Sbjct: 2344 SGIGHGQASSAVRDSGHRGSSG----SQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQES 2399
Query: 620 SPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPS 679
+ +A + + +S ++ + S S + + Q + ++ + +
Sbjct: 2400 TRGRSAGR-----SGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHST 2454
Query: 680 SVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKG 739
S E +D+ + S Y +V + G + T
Sbjct: 2455 SQEGQDT---------IHGHPGSSSGGRQGSHYEQLVD-----RSGHSGSHHSHTTSQGR 2500
Query: 740 EKKNVPEKHTREAQKQA-SEKVSNKGKR---KHKNEDDNRASESKKPKTEDKNSAGHKPS 795
+ +R A +Q +++ S G R +E +RA S + S G + S
Sbjct: 2501 SDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTS 2560
Query: 796 SN------RESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK 849
N ++S Q +++ + A + HGS + + S S ++
Sbjct: 2561 RNWGSSFSQDSDSQGHSEDSERWSGSAS-------RNHHGSAQEQLRDGSRHPRSHQEDR 2613
Query: 850 ETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSS 886
G S +SS S + T+ + + E+A SS+
Sbjct: 2614 AGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSA 2650
Score = 66.6 bits (161), Expect = 1e-10
Identities = 173/859 (20%), Positives = 289/859 (33%), Gaps = 134/859 (15%)
Query: 96 EQRHGGS--HQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDR 153
E++ G S H S+ S+ + G G R GSS +S + H
Sbjct: 3168 EEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQ-GSSVSQDSDSEGHSE 3226
Query: 154 ESYNNSGSSSR-------KKGQHGSEHSKS-------------RSSSPGKPQAVSSLN-- 191
+S SGS+SR ++ +HGS H +S RS G A +S
Sbjct: 3227 DSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQ 3286
Query: 192 --SSH--SRSHGNDHHSKEHQRSKS-------PRDPDANWDSPSRVPFSSGQHSTQSFPP 240
SSH +RS + H HQ+S PR ++ SR SSG ++ S
Sbjct: 3287 AASSHEQARSSPGERHGSRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGH 3346
Query: 241 SLMSKSNSMLQKPTAYVRPMDGQESMEPK--------------LSSEHYSSQSHGNSMTE 286
S S + S+ A QES + +S+ S +HG + T
Sbjct: 3347 SEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTS 3406
Query: 287 LKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFP 346
+H + + S+ AS G ++ P S+
Sbjct: 3407 TGRRQGSHHEQARDSSRH-SASQEG---------QDTIRGHP------------GSSRRG 3444
Query: 347 FPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRST 406
+QS +G ++ TS G S + + +S + + EQ D
Sbjct: 3445 RQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGD------- 3497
Query: 407 PGSNSEPSHHN--SEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP 464
GS SHH+ S AD+SR S S S ++ S S DS+ SQ S +
Sbjct: 3498 -GSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSD----SQGHSEDS 3552
Query: 465 EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKET 524
E +W ++ + S S P+S + G +S + E
Sbjct: 3553 E-----RW--SGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAEN 3605
Query: 525 SSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI 584
SS S Q S +G QS +++ +G Q A + + G
Sbjct: 3606 SSGGQAASSHE-QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSG--- 3661
Query: 585 ESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREII 644
S+ S S + G P+ + +S+ + +S +S + +
Sbjct: 3662 -SQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQEST--------RGRSAGRSGRSGSFLY 3712
Query: 645 ETDTSSSDSDESESLPPSS---QTPKYPESNRTPVKPSSVEEEDSFFRQ-------RMFS 694
+ T PS+ Q ++ ++ + +S E +D+ R S
Sbjct: 3713 QVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGS 3772
Query: 695 PMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQK 754
E+ S S + T G+ ++ G+ + ++
Sbjct: 3773 YHEQSVDRSGHSGSHHSH-----------TTSQGR----SDASHGQSGSRSASRETRNEE 3817
Query: 755 QASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPS 814
Q+ + + G R H E +A S+ ++ SAG + S R+ S S + + P
Sbjct: 3818 QSGDGSRHSGSRHH--EASTQADSSRHSQSGQGESAGSR-RSRRQGSSVSQDSDSEAYPE 3874
Query: 815 PAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSS 874
+ + HGS + S SS+ + + S S S K G SS
Sbjct: 3875 DSERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSL 3934
Query: 875 SKEVKEKAPSSSSNCPPSA 893
S++ + S P S+
Sbjct: 3935 SQDSAYHSGIQSRGSPHSS 3953
Score = 66.2 bits (160), Expect = 2e-10
Identities = 179/870 (20%), Positives = 293/870 (33%), Gaps = 144/870 (16%)
Query: 87 DEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSA--GSSSGT 144
DE+S RH GS A S + S S Q RTS GSS
Sbjct: 2520 DEQSGDG---SRHSGSRHHE-------ASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQ 2569
Query: 145 NSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHS 204
+S Q H +S SGS+SR HGS + R S H RSH D
Sbjct: 2570 DSDSQGHSEDSERWSGSASR--NHHGSAQEQLRD------------GSRHPRSHQEDRAG 2615
Query: 205 KEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQE 264
H S + SG TQ+ + S+ + Q+
Sbjct: 2616 HGHSADSSRQ---------------SGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2660
Query: 265 SMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMT 324
S + S +S HG + + ++ S + + S S D V + +
Sbjct: 2661 SAD----SSRHSGIGHGQASSAVRDSGHRGYSGSQ-ASDNEGHSEDSDTQSVSAHGQAGS 2715
Query: 325 HSWPPPLTAIHTPCKTEPSKFPF----PTKESQQSNFG-TGEQKRYNPSKTSNGHQSKSM 379
H +A +T F T E +S+ G TG PS
Sbjct: 2716 HQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG------PSTRGRQGSRHEQ 2769
Query: 380 LKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGS-ESSS 438
+D + S+S+D QD + P S+ G H +S DSS HSGS S +
Sbjct: 2770 AQDSSRHSASQDG---QDTIRGHPGSSRGGRQGYHHEHSV-------DSSGHSGSHHSHT 2819
Query: 439 GSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPS 498
S S++S S + S++ E + ++ + H+ S + + + +
Sbjct: 2820 TSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRH------SGSRHHEASTHADISRHSQA 2873
Query: 499 SQGY---KKEGREQGTGNSY-TDTSGPKETSSATPGRDSKT--------IQKGSESGRGR 546
QG + R QG+ S +D+ G E S G S+ ++ GS R
Sbjct: 2874 VQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSH 2933
Query: 547 QKSPA----QSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK 602
Q+ A +DS+ Q T + + A++ E A S H+
Sbjct: 2934 QEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQAR----------SSAGERHGSHHQ 2983
Query: 603 AATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPS 662
+ SR I SS + + Y + S + + S DSD ++S+
Sbjct: 2984 QSADSSRHSGIGHGQASSAVRDSGHRGYSGSQAS--------DNEGHSEDSD-TQSVSAH 3034
Query: 663 SQTPKYPESNRTPVKPSSVE---EEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKID 719
Q + +S++ + S E SF Q S E+ E + P R
Sbjct: 3035 GQAGSHQQSHQESARGRSGETSGHSGSFLYQ--VSTHEQSESSHGWTGPSTR-------- 3084
Query: 720 LNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQK--QASEKVSNKGKRKHKNEDDNRAS 777
G+ E + ++ ++ ++ + S + +G + D + S
Sbjct: 3085 --------GRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHS 3136
Query: 778 ESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQ 837
S T S G +S +S +SA++ + S D SR S
Sbjct: 3137 GSHHSHT---TSQGRSDASRGQSGSRSASR------TTRNEEQSGDSSRHSVSRHHEAST 3187
Query: 838 SSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLD 897
+ + S + + S S+ S + + S++ + + S+S N S
Sbjct: 3188 HADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQS 3247
Query: 898 SSKPRRTKLVFDDR---NYSADHYLQEAKK 924
R + +DR +SAD Q +
Sbjct: 3248 RHGSRHPRSHHEDRAGHGHSADRSRQSGTR 3277
Score = 65.9 bits (159), Expect = 2e-10
Identities = 171/836 (20%), Positives = 279/836 (33%), Gaps = 164/836 (19%)
Query: 97 QRHGGSHQ----SSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHD 152
+RHG HQ SS+ + +G Q S+ SGH G S S + H
Sbjct: 2976 ERHGSHHQQSADSSRHSGIG------HGQASSAVRDSGHR------GYSGSQASDNEGHS 3023
Query: 153 RESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVS-------SLNSSHSRSHG-NDHHS 204
+S S S+ + G H H +S G+ S S + SHG +
Sbjct: 3024 EDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPST 3083
Query: 205 KEHQRSKSPRDPDANWDSPSRV--------PFSSG--------QHSTQSFPPSLMSKSNS 248
+ Q S+ + D++ S S+ P SS +HS S S S++
Sbjct: 3084 RGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHT 3143
Query: 249 MLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTEL-KPSSKAHLTKLKIPSQPLDA 307
Q + R G S +E S S +S++ + S+ A +++ SQ +
Sbjct: 3144 TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISR---HSQAVQG 3200
Query: 308 SASGDV------SCVDEILKEMTHS-----WPPPLTAIHTPCKTEPSKFPFPTKESQQSN 356
+ G S V + HS W + H E QS
Sbjct: 3201 QSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE------------QSR 3248
Query: 357 FGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHH 416
G+ + ++ + +GH + + + + + S G+ RS+PG H
Sbjct: 3249 HGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETS-SGGQAASSHEQARSSPGERHGSRHQ 3307
Query: 417 NSEGADNSRDDS------------SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP 464
S AD+SR S H GS S SDSE S SD +QS S
Sbjct: 3308 QS--ADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESD------TQSVSGH- 3358
Query: 465 EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKET 524
+ PH+ S S + G G S+ E
Sbjct: 3359 --------------GQAGPHQQSHQESARD---------RSGGRSGRSGSFLYQVSTHEQ 3395
Query: 525 SSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI 584
S + GR + +GR RQ S + + R + ++ RG
Sbjct: 3396 SESAHGRTR------TSTGR-RQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGS 3448
Query: 585 ESETPVDLASSMPSSRHKAATKGSRKPNIKKE--SKSSPRPTAEKKKYKSTSKSSQKSRE 642
E VD S S H T R + + S+S+ R T ++ S+ S
Sbjct: 3449 HYEQSVD-RSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHH 3507
Query: 643 IIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELL 702
E T + S S+S S P+ + + V S + S E+ E
Sbjct: 3508 --EASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHS----------EDSERW 3555
Query: 703 SPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSN 762
S + + R G +++ G + R ++E
Sbjct: 3556 SGSASRNHR----------------GSAQEQSR--DGSRHPTSHHEDRAGHGHSAESSRQ 3597
Query: 763 KGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSK 822
G +N +A+ S + + ++SAG + S+ + S S+ S G +
Sbjct: 3598 SGTHHAENSSGGQAASSHE---QARSSAGERHGSHHQQSADSSRH------SGIGHGQAS 3648
Query: 823 DPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSS---STSKQKKTEGKTSSSS 875
+ G R + SQ+S + S + S S+ + S Q+ T G+++ S
Sbjct: 3649 SAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 3704
Score = 65.5 bits (158), Expect = 3e-10
Identities = 161/830 (19%), Positives = 278/830 (33%), Gaps = 113/830 (13%)
Query: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRH------- 151
H GSH S + S + + SG +S + R S G+ SG RH
Sbjct: 2811 HSGSHHSHT-----TSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHA 2865
Query: 152 --DRESYNNSGSS--SRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEH 207
R S G S SR+ + GS S+ S S G + + S SR+H +
Sbjct: 2866 DISRHSQAVQGQSEGSRRSRRQGSSVSQD-SDSEGHSEDSERWSGSASRNHHGSAQEQLR 2924
Query: 208 QRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESME 267
S+ PR + SS Q T+ S ++ S ++ + G +
Sbjct: 2925 DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQ 2984
Query: 268 PKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSW 327
SS H S HG + + ++ S + + S S D V + +H
Sbjct: 2985 SADSSRH-SGIGHGQASSAVRDSGHRGYSGSQA-SDNEGHSEDSDTQSVSAHGQAGSHQQ 3042
Query: 328 PPPLTAIHTPCKTEPSKFPF----PTKESQQSNFG-TG------EQKRYNPSKTSNGHQS 376
+A +T F T E +S+ G TG + R+ ++ S+ H +
Sbjct: 3043 SHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSA 3102
Query: 377 KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPG-SNSEPSHHNSEG-ADNSRDDSSSHSGS 434
+D ++ G Q + G S S SH S+G +D SR S S S S
Sbjct: 3103 SQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3162
Query: 435 ESSSGSDSESESS----------SSDSEANEPSQSASPEPEPPPTNKWQ----------- 473
++ + +SS S+ ++ + SQ+ + E ++ Q
Sbjct: 3163 RTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE 3222
Query: 474 -----LDNWLNKVNPH---KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETS 525
+ W + + V S S P S + G S + ETS
Sbjct: 3223 GHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETS 3282
Query: 526 SATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIE 585
S S + S R + +DS+ + PRG
Sbjct: 3283 SGGQAASSHEQARSSPGERHGSRHQQSADSSRH----------------SGIPRG----- 3321
Query: 586 SETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIE 645
+S++ SRH ++ GS+ + + S+ S + + Q+S +
Sbjct: 3322 -----QASSAVRDSRHWGSS-GSQASDSEGHSEES---DTQSVSGHGQAGPHQQSHQESA 3372
Query: 646 TDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPL 705
D S S S S T + ES + S+ + S Q S S
Sbjct: 3373 RDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDS--------SRH 3424
Query: 706 SEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGK 765
S + I + G Y+++ G + T + + AS S
Sbjct: 3425 SASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRS 3484
Query: 766 RKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPK 825
+ +D ++ + + H S + E+S Q+ + S +G S P+
Sbjct: 3485 ASRQTRNDEQSGDGSR----------HSWSHHHEASTQADSSRH----SQSGQGQSAGPR 3530
Query: 826 TEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSS 875
T S S S +S + + +S+N +++++ +G +S
Sbjct: 3531 TSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTS 3580
Score = 64.3 bits (155), Expect = 6e-10
Identities = 162/828 (19%), Positives = 277/828 (33%), Gaps = 104/828 (12%)
Query: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNN 158
H GSH S + S QS RS Q+ + Q S G+ SG RH
Sbjct: 1838 HSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQ-----SGDGSRHSGSRHHE----- 1887
Query: 159 SGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDA 218
+SSR S+ + +SS P + S S S S G+ S+ S S +
Sbjct: 1888 --ASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGS 1945
Query: 219 NWDSP---SRVP--------------FSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD 261
W+ SR P SS Q T+ S ++ S ++ +
Sbjct: 1946 AWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERH 2005
Query: 262 GQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEIL- 320
G S +S HG + + ++ S + SQ D+ + S +
Sbjct: 2006 GSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYS----GSQASDSEGHSEDSDTQSVSA 2061
Query: 321 ------KEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFG-----TG--EQKRYNP 367
+ +H + + ++ + T E +S G TG + Y+
Sbjct: 2062 QGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQ 2121
Query: 368 SKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPG-SNSEPSHHNSEG-ADNSR 425
++ S+ H + +D ++ G Q + G S S SH S+G +D SR
Sbjct: 2122 AQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASR 2181
Query: 426 DDSSSHSGSESSSGSDSESESS-SSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPH 484
S S S S + + + S S S +E S A +++ L P
Sbjct: 2182 GQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD-------SSRHSLVGQGQSSGPR 2234
Query: 485 KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGR 544
P S S S+G+ E E+ +G++ + G + S R ++ +
Sbjct: 2235 TSRPRGSSVSQDSDSEGH-SEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHG 2293
Query: 545 GRQKSPAQSDSTTQRRTVGKKQPKKAEKA--AAEEPRGGLKIESETPVDLASSMPSSRHK 602
+S QS + + G + E+A +A E G S SSRH
Sbjct: 2294 HSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGS---------HHQQSADSSRHS 2344
Query: 603 AATKGSRKPNIK----KESKSSPRPTAEKKKYKSTSKS---------SQKSREIIETDTS 649
G ++ + S S +E S ++S Q+S + S
Sbjct: 2345 GIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRS 2404
Query: 650 SSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPD 709
+ S S S T + ES S+ + S +Q S S E
Sbjct: 2405 AGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRH-----STSQEGQ 2459
Query: 710 DRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK 769
D I G P + +G + + S S +G+
Sbjct: 2460 D--------------TIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTS-QGRSDAS 2504
Query: 770 NEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHG 829
+ S S++ + ++++ G + S +R S A S G S+ P+T
Sbjct: 2505 HGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSG--HSQVGQGQSEGPRTSRN 2562
Query: 830 SRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKE 877
S S S +S + + +S+N +++++ +G S +
Sbjct: 2563 WGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQ 2610
Score = 60.5 bits (145), Expect = 9e-09
Identities = 110/474 (23%), Positives = 160/474 (33%), Gaps = 86/474 (18%)
Query: 104 QSSKWTPVGPAPSTSQSQKRSSGLQS-GHS---------SQRTSAGSSSGTNSSGQRH-- 151
QS + GP S +Q S S GHS + R GS+ + G RH
Sbjct: 3520 QSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPT 3579
Query: 152 ----DRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEH 207
DR + +S SSR+ G H +E+S ++ QA SS H H S H
Sbjct: 3580 SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH 3639
Query: 208 ------QRSKSPRDPDANWDSPSRVPFSSG-----------------------QHSTQSF 238
Q S + RD S S+ S G Q ST+
Sbjct: 3640 SGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGR 3699
Query: 239 PPSLMSKSNSML-------QKPTAYVRP------MDGQESMEPKLSSEHYSSQSHGNSMT 285
+S S L Q +A+ R G + + SS H +SQ G
Sbjct: 3700 SAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQE-GQDTI 3758
Query: 286 ELKPSSKAHLTKLKIPSQPLDASA---SGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEP 342
P S+ + Q +D S S + + +H +A E
Sbjct: 3759 RGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQ 3818
Query: 343 SKFPFPTKESQQSNFGT-GEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKT 401
S S+ T + R+ S++ G + S S S+DSD E + +
Sbjct: 3819 SGDGSRHSGSRHHEASTQADSSRH--SQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDS 3876
Query: 402 MPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESS-SGSDSESESSSSDSEANEPSQSA 460
RS S + + D SR SSH + S S +S+SS++ + S S
Sbjct: 3877 ERRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQ 3936
Query: 461 SPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNS 514
D+ + + SP SS SS Y+ EG E+ G S
Sbjct: 3937 --------------DSAYHSGIQSRGSPHSS------SSYHYQSEGTERQKGQS 3970
Score = 59.7 bits (143), Expect = 2e-08
Identities = 143/818 (17%), Positives = 280/818 (34%), Gaps = 113/818 (13%)
Query: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNN 158
H H+ +K +++KR S L+ ++ + S S + G+RH+ S
Sbjct: 106 HHDKHEDNK------QEENKENRKRPSSLERRNNRKGNKGRSKSPRETGGKRHESSSEKK 159
Query: 159 SG---SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRD 215
S + ++ ++G H S K + ++R N E K +
Sbjct: 160 ERKGYSPTHREEEYGKNHHNSSKKEKNK--------TENTRLGDNRKRLSERLEEKEDNE 211
Query: 216 PDA-NWDSPSRVP---FSSGQHST-QSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKL 270
++++ R+ SG +T + ++S+L++ Y R S + K
Sbjct: 212 EGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYER----SRSSDGKS 267
Query: 271 SSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTH---SW 327
SS+ S+ S L+ S ++ SQ D+ + S H +W
Sbjct: 268 SSQVNRSRHENTSQVPLQESRTRKRRGSRV-SQDRDSEGHSEDSERHSGSASRNHHGSAW 326
Query: 328 PPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLS 387
+QS G+ + ++ + S+GH + S + +
Sbjct: 327 -------------------------EQSRDGSRHPRSHDEDRASHGHSADSSRQSGTR-H 360
Query: 388 SSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSS------------SHSGSE 435
+ S G+ RS+PG H S AD+SR ++ H GS
Sbjct: 361 AETSSRGQTASSHEQARSSPGERHGSGHQQS--ADSSRHSATGRGQASSAVSDRGHRGSS 418
Query: 436 SSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSN 495
S SDSE S +SD+++ A + +++ + + S V ++
Sbjct: 419 GSQASDSEGHSENSDTQSVSGHGKAGLRQQ---SHQESTRGRSGERSGRSGSSLYQVSTH 475
Query: 496 IPSSQGYKKEGREQG--TGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQS 553
+ + G G G+ + S++ G+D TI+ S RG ++
Sbjct: 476 EQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQD--TIRGHPGSSRGGRQGSHHE 533
Query: 554 DSTTQRRTVGKKQPKKAEKAAAEEPRG--GLKIESETPVDLASSMPSSRHKAATKGSRKP 611
S + G + ++ G G + S + S +RH GSR
Sbjct: 534 QSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRH----SGSRHH 589
Query: 612 NIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPES 671
++ SS + + S + + + S S++SE S+ +
Sbjct: 590 EASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHH--- 646
Query: 672 NRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPY 731
S +E+ + S E++ D + N + +
Sbjct: 647 -------GSAQEQSRDGSRHPRSHHEDR--AGHGHSADSSRKSGTRHTQNSSSGQAASSH 697
Query: 732 KETEPPKGEKKNV--------PEKHTREAQKQASEKVSNKGKR----KHKNEDDNRASES 779
++ GE+ +H+ QAS V + G R + + + +S
Sbjct: 698 EQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDS 757
Query: 780 KKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPS-KDPKTEHGSRKRTISQS 838
AGH S++ES++ + + S V + K ++ HG S
Sbjct: 758 DTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHG----WTGPS 813
Query: 839 SSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSK 876
+ ++ S+ +++ +S++S+S Q G SS +
Sbjct: 814 TGVRQGSH-HEQARDNSRHSASQDGQDTIRGHPGSSRR 850
Score = 50.8 bits (120), Expect = 7e-06
Identities = 115/624 (18%), Positives = 224/624 (35%), Gaps = 89/624 (14%)
Query: 361 EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE-------- 412
+ ++ + + ++K K L + G + K+ PR T G E
Sbjct: 103 KHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGRSKS-PRETGGKRHESSSEKKER 161
Query: 413 ----PSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPP 468
P+H E N + S ++ + S E E ++ + E
Sbjct: 162 KGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTG 221
Query: 469 --TNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526
T KW + + + DS + ++ Y++ G +S + S + TS
Sbjct: 222 RMTQKWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQ 281
Query: 527 ATPGRDSKTIQK-GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIE 585
P ++S+T ++ GS + R DS + + +A E+ R G +
Sbjct: 282 V-PLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNH----HGSAWEQSRDGSRHP 336
Query: 586 SETPVDLASSMPSS--------RHKAATKGSRKPNIKKESKSSP--------RPTAEKKK 629
D AS S+ RH + + + ++++SSP + +A+ +
Sbjct: 337 RSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSR 396
Query: 630 YKSTSKSSQKSR--EIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSF 687
+ +T + S + +S S + +SE +S T + ++ S +E +
Sbjct: 397 HSATGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQS-HQESTR 455
Query: 688 FRQRMFSPMEEKEL--LSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVP 745
R S L +S +PD + G+ T +G
Sbjct: 456 GRSGERSGRSGSSLYQVSTHEQPDSAH---------------GRTGTSTGGRQGSHHEQA 500
Query: 746 EKHTREAQKQASEKV------SNKGKRK--HKNEDDNRASES----KKPKTEDKNSAGHK 793
+R + Q + S++G R+ H + NR+ S ++ ++ A H
Sbjct: 501 RDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHG 560
Query: 794 PSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSR-KRTISQSSSLKSSSNSNKETS 852
S +R +S+Q+ +E+ S D GSR SQ+ S + S ++S
Sbjct: 561 QSGSRSASRQTRNEEQ-----------SGDGTRHSGSRHHEASSQADSSRHSQVGQGQSS 609
Query: 853 G--SSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDD 910
G +S+N S+ Q + + S++ + + S+S N SA R + +D
Sbjct: 610 GPRTSRNQGSSVSQ---DSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHED 666
Query: 911 R---NYSADHYLQEAKKLKHNADA 931
R +SAD + + N+ +
Sbjct: 667 RAGHGHSADSSRKSGTRHTQNSSS 690
Score = 41.2 bits (95), Expect = 0.006
Identities = 77/393 (19%), Positives = 144/393 (36%), Gaps = 49/393 (12%)
Query: 490 SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKS 549
S+ N+P S G+K + KE + + +KG+ +GR KS
Sbjct: 88 STRKENLPIS-GHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGN---KGRSKS 143
Query: 550 PAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSR 609
P R T GK+ +EK +E +G E S + K T+ +R
Sbjct: 144 P--------RETGGKRHESSSEK---KERKGYSPTHREEEYGKNHHNSSKKEKNKTENTR 192
Query: 610 KPNIKKESKSSPRPTAEKKK----YKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQT 665
+ +K + ++ Y++T + +QK + T + DE+
Sbjct: 193 LGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQKWIQSGHIATYYTIQDEAYD------- 245
Query: 666 PKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTR 725
S +EE + R R ++ E + PL + +
Sbjct: 246 ----------TTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPL----QESRTRK 291
Query: 726 IPGKPYKETEPPKGEKKNVPEKHTREAQKQ---ASEKVSNKGKRKHKNEDDNRASESKKP 782
G + +G ++ E+H+ A + ++ + S G R ++ D++RAS
Sbjct: 292 RRGSRVSQDRDSEGHSED-SERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSA 350
Query: 783 KTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLK 842
+ ++ H +S+R Q+A+ + SP S ++ SR + +
Sbjct: 351 DSSRQSGTRHAETSSR---GQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQA-- 405
Query: 843 SSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSS 875
SS+ S++ GSS + +S S+ T S S
Sbjct: 406 SSAVSDRGHRGSSGSQASDSEGHSENSDTQSVS 438
Score = 39.3 bits (90), Expect = 0.022
Identities = 43/193 (22%), Positives = 79/193 (40%), Gaps = 22/193 (11%)
Query: 698 EKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQAS 757
EKE L PDD P +V + ++ L K TE K + E+ ++ +
Sbjct: 38 EKEFRQILKNPDD--PDMVDVFMDHLDIDHNKKIDFTEFLLMVFKLAQAYY--ESTRKEN 93
Query: 758 EKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAG 817
+S RKH + D + ++ ++ K K + + +NR+ +K
Sbjct: 94 LPISGHKHRKHSHHDKHEDNKQEENKENRKRPSSLERRNNRKGNKGR------------- 140
Query: 818 PVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETS-GSSKNSSSTSKQKKTEG-KTSSSS 875
SK P+ G R + S+ K S +++E G + ++SS ++ KTE + +
Sbjct: 141 ---SKSPRETGGKRHESSSEKKERKGYSPTHREEEYGKNHHNSSKKEKNKTENTRLGDNR 197
Query: 876 KEVKEKAPSSSSN 888
K + E+ N
Sbjct: 198 KRLSERLEEKEDN 210
Score = 36.6 bits (83), Expect = 0.14
Identities = 33/141 (23%), Positives = 51/141 (36%), Gaps = 8/141 (5%)
Query: 98 RHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYN 157
RH GS T + + Q S+G S + GSS +S + + +S
Sbjct: 3824 RHSGSRHHEASTQADSSRHSQSGQGESAG-----SRRSRRQGSSVSQDSDSEAYPEDSER 3878
Query: 158 NSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPD 217
S S+SR E S+ S PG ++ + S + +KEH S
Sbjct: 3879 RSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDS 3938
Query: 218 ANWDSPSRVPFSSGQHSTQSF 238
A S + HS+ S+
Sbjct: 3939 A---YHSGIQSRGSPHSSSSY 3956
>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
Length = 715
Score = 90.9 bits (224), Expect = 6e-18
Identities = 154/671 (22%), Positives = 253/671 (37%), Gaps = 100/671 (14%)
Query: 102 SHQSSKWTPVGPAPS---TSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNN 158
S +S+K T APS +S+S+ RS S T +S S + H R ++
Sbjct: 61 SSKSTKSTSTKRAPSNRPSSRSRVRSKARTPSRVSTDTRTSKASKA-SDVRCHQRRGTHS 119
Query: 159 SGSSSRKKGQHGSEHSKSRSSSPGKPQA--------------VSSLNSSHSRSHGNDHHS 204
G + ++G S+ S SR+S+PG+ + S S +S+G S
Sbjct: 120 RGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRPRTS 179
Query: 205 KEHQRSKSPRDPDANWDSP---SRVPFSSGQHSTQS-----FPPSLMSKSNSMLQKPTAY 256
+ PR+ P S + SS T S P + SK S P++
Sbjct: 180 NRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSS 239
Query: 257 VRPMD-GQ---ESMEPKLSSEHYSS--QSHGNSMTELKPSSKAHLTKLKIPSQPLDASAS 310
+ GQ S E S SS +S+ + T +P S + S+ S S
Sbjct: 240 RKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQ-------SRSPRRSRS 292
Query: 311 GDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKT 370
G ++ +HSW H+ ++ K + + K N S+T
Sbjct: 293 GSQKRTHSRVR--SHSW----KRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRT 346
Query: 371 SNGHQSKSMLKDDLK-------LSSSEDSD--GEQDCDKTMPRSTPGS-NSEPSHHNSEG 420
+S + ++ K SSS++ D G K RS GS N + H S
Sbjct: 347 PRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRS 406
Query: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDS-------EANEPSQSASPEPEPPPTNKWQ 473
+ +RD S S S ++ S S S + + D +A + S+S SP
Sbjct: 407 PNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSP----------- 455
Query: 474 LDNWLNKVNPH--KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGR 531
NK H SP + D + S +++ + G+ + D + S R
Sbjct: 456 -----NKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCR 510
Query: 532 DSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEE-----------PRG 580
S++ K E R +SP++ Q R+ K++ + ++ +EE R
Sbjct: 511 QSRSSSK--ERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERD 568
Query: 581 GLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKS 640
+ S + SS + SR PN K+ S PR + K+K S S++ K
Sbjct: 569 RRRWRSPSKERERRQSRSSSEERDHSRSRSPN-KQSGYSRPR-ASSKEKAHSRSRTPSKE 626
Query: 641 REIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKE 700
++ TSS +SD P S P+ P+ R+P + SS+ + + + SP
Sbjct: 627 GNHSQSRTSSKESD-----PSQSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPS 681
Query: 701 LLSPLSEPDDR 711
LS+ D +
Sbjct: 682 GGQTLSQDDSQ 692
Score = 84.7 bits (208), Expect = 5e-16
Identities = 165/822 (20%), Positives = 301/822 (36%), Gaps = 161/822 (19%)
Query: 85 SADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGT 144
S S P+ G S ++ P ST + S + + ++ R S S S +
Sbjct: 3 SPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRNSVMSPSSS 62
Query: 145 NSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHS 204
S+ + + +N SS + +S++ +P + + + + S H
Sbjct: 63 KSTKSTSTKRAPSNRPSSRSRV--------RSKARTPSRVSTDTRTSKASKASDVRCHQR 114
Query: 205 K-EHQRSKSP--RDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD 261
+ H R ++P R ++ SPSR + G+ T P + S+ ++ PT+ +
Sbjct: 115 RGTHSRGRTPGRRGSRSSKRSPSRAS-TPGRIRTHGARPGMASR----VRTPTSQQKGSR 169
Query: 262 GQESMEPKLSS-EHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEIL 320
G+ P+ S+ E SQ S +P + + + S +++
Sbjct: 170 GKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIGR------------SSELAVTPSTA 217
Query: 321 KEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT----GEQKRYNPSKTSNGHQS 376
K T + P E S P P+ + ++G +K Y+P++ S+ +S
Sbjct: 218 KCQTPTGIP---------SKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKS 268
Query: 377 KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHH----NSEGADNSRDDSSSHS 432
+ +S S + PR + + + +H +S ++SR S +
Sbjct: 269 YNQ--------ASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRK 320
Query: 433 GSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSV 492
G S G S+S S S SQ+ S P ++ W + +K H S +SS
Sbjct: 321 GILSQMGRHSQSRSHSKGK-----SQNQSRTPRRGRSHNWSRNP--SKERSHSHSRSSSK 373
Query: 493 DSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRD-SKTIQKGSESGRGRQKSPA 551
+ + S +KE SG ++ S RD S++ R R +SP
Sbjct: 374 ERDHRGSSSPRKE-------------SGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPY 420
Query: 552 QSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKG-SRK 610
++ ++ R+ P KA S S +KA + SR
Sbjct: 421 KARDRSRSRS-----PNKARDC---------------------SRSRSPYKARDRSRSRS 454
Query: 611 PNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPE 670
PN ++ S P K + +S S+S K R+ + + S + D S PS +
Sbjct: 455 PNKARDHSRSRSPN--KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKE------ 506
Query: 671 SNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKP 730
+ SS +E D +R SP +E++ R P
Sbjct: 507 -RQCRQSRSSSKERD---HRRSRSPSKERQ-----------------------RRQSRSP 539
Query: 731 YKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSA 790
KE + + + +H +Q+ + +R+ ++ R + +E+++
Sbjct: 540 NKERDRSQSRSPSEEREH-----RQSRSPSKERDRRRWRSPSKERERRQSRSSSEERDH- 593
Query: 791 GHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKE 850
S +R +KQS P K + SR RT S+ + S S+KE
Sbjct: 594 ----SRSRSPNKQSGYSR-----------PRASSKEKAHSRSRTPSKEGNHSQSRTSSKE 638
Query: 851 TSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPS 892
+ S + K++ +TSS S + + PS +S+ PS
Sbjct: 639 SDPSQSTVPRSPDWKRSPTRTSSLS---QNRTPSKTSSHSPS 677
Score = 69.7 bits (169), Expect = 2e-11
Identities = 94/387 (24%), Positives = 150/387 (38%), Gaps = 49/387 (12%)
Query: 98 RHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGH----SSQRTSAGSSSGTNSSGQRHDR 153
R G SH S+ P+ S S RSS + H S ++ S S SG+ + + H R
Sbjct: 348 RRGRSHNWSR----NPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSR 403
Query: 154 ESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSH-----SRSHGNDHHSKEHQ 208
N + +SRS SP K + S S + SRS + + +++H
Sbjct: 404 SRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSR-SPNKARDHS 462
Query: 209 RSKSPRDPDANWDSPSRVPFSSGQHSTQSFPP-------SLMSKSNSMLQKPTAYVRPMD 261
RS+SP A S SR P HS P S ++ + + D
Sbjct: 463 RSRSPN--KARDRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERD 520
Query: 262 GQESMEPKLSSEHYSSQSHGNSMTELK---PSSKAHLTKLKIPSQPLDASASGDVSCVDE 318
+ S P + S+S + PS + + + PS+ D S E
Sbjct: 521 HRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERE 580
Query: 319 ILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKS 378
+ + S + +P K S + P S++ + PSK N QS+
Sbjct: 581 RRQSRSSSEERDHSRSRSPNK--QSGYSRPRASSKEK----AHSRSRTPSKEGNHSQSR- 633
Query: 379 MLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSS 438
+SS++SD Q T+PRS P P+ +S + + +SSHS S S
Sbjct: 634 --------TSSKESDPSQ---STVPRS-PDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPS 681
Query: 439 G----SDSESESSSSDSEANEPSQSAS 461
G S +S++ ++ S+A P + +S
Sbjct: 682 GGQTLSQDDSQADATTSKATLPGERSS 708
Score = 63.5 bits (153), Expect = 1e-09
Identities = 102/442 (23%), Positives = 167/442 (37%), Gaps = 66/442 (14%)
Query: 101 GSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSG 160
G H S+ G + + S++ +R + + + S S ++S + H S
Sbjct: 327 GRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKE 386
Query: 161 SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANW 220
S + G + SRS SP K + + S SRS + +++ RS+SP A
Sbjct: 387 SGRSQSGSPNKQRDHSRSRSPNKAR-----DRSRSRS---PYKARDRSRSRSPN--KARD 436
Query: 221 DSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSH 280
S SR P+ + S P ++ +S + P + D S P +H S
Sbjct: 437 CSRSRSPYKARDRSRSRSPNK--ARDHSRSRSPN---KARDRSRSRSPSKERDHSQLGS- 490
Query: 281 GNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCK- 339
PS + + + PS+ S S + + + S +P K
Sbjct: 491 --------PSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKE 542
Query: 340 --TEPSKFPFPTKESQQSNFGTGEQKR---YNPSKTSNGHQSKSMLKDDLKLSSSEDSDG 394
S+ P +E +QS + E+ R +PSK QS+ SSSE+ D
Sbjct: 543 RDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSR---------SSSEERDH 593
Query: 395 EQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEAN 454
+ +P S S + +S++ + S S + S G+ S+S +SS +S+ +
Sbjct: 594 SRS-------RSPNKQSGYSRPRA----SSKEKAHSRSRTPSKEGNHSQSRTSSKESDPS 642
Query: 455 EPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNS 514
+ + SP+ + PT L P K S S S PS G S
Sbjct: 643 QSTVPRSPDWKRSPTRTSSLS---QNRTPSKTS--SHSPSTFPSG----------GQTLS 687
Query: 515 YTDTSGPKETSSAT-PGRDSKT 535
D+ TS AT PG S +
Sbjct: 688 QDDSQADATTSKATLPGERSSS 709
Score = 43.9 bits (102), Expect = 9e-04
Identities = 69/313 (22%), Positives = 119/313 (38%), Gaps = 48/313 (15%)
Query: 603 AATKGSRKPNIKKESKSSPRPTAEKKKYKS--TSKSSQKSREIIETDTSSSDSDESESLP 660
++ K S KP++ S PTA+ K S ++KS+ +R ++ T ++S + S P
Sbjct: 2 SSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATSRN--SVMSP 59
Query: 661 PSSQTPKYPESNRTPV-KPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKID 719
SS++ K + R P +PSS S + R S + S S+ D +
Sbjct: 60 SSSKSTKSTSTKRAPSNRPSSRSRVRS--KARTPSRVSTDTRTSKASKASD-VRCHQRRG 116
Query: 720 LNLLTRIPGK---------PYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKN 770
+ R PG+ P + + P + + S++ ++GK +
Sbjct: 117 THSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGARPGMASRVRTPTSQQKGSRGKSYGRP 176
Query: 771 EDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSA---------------AKEKDLLPSP 815
NR +P+ K S S S + A +KEK PSP
Sbjct: 177 RTSNRERSDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSP 236
Query: 816 AGP----------VPSKDPK---TEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTS 862
+ +PS++ TE SR ++ +Q+S + S + S S +
Sbjct: 237 SSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQAS---TRSRPQSHSQSRSPRRSRSG 293
Query: 863 KQKKTEGKTSSSS 875
QK+T + S S
Sbjct: 294 SQKRTHSRVRSHS 306
Score = 33.9 bits (76), Expect = 0.93
Identities = 45/181 (24%), Positives = 70/181 (38%), Gaps = 16/181 (8%)
Query: 7 NVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKE-DKLSSRIQSMLGNYDEMKDF 65
N R + + R E ++ + PS ++ SKE ++ SR S E +D
Sbjct: 540 NKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQSRSSS------EERDH 593
Query: 66 IGDRSIPKLVAIPKPTVPPS--ADEKSNPNFFEQRHGGSHQSSK-----WTPVGPAPSTS 118
RS K +P A +S E H S SSK + V +P
Sbjct: 594 SRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRSPDWK 653
Query: 119 QSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRS 178
+S R+S L + +TS+ S S S GQ ++ ++ ++ K E S S S
Sbjct: 654 RSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQD--DSQADATTSKATLPGERSSSSS 711
Query: 179 S 179
S
Sbjct: 712 S 712
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 85.9 bits (211), Expect = 2e-16
Identities = 154/752 (20%), Positives = 275/752 (36%), Gaps = 97/752 (12%)
Query: 162 SSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWD 221
SSR+K + + +S SP + S + RSH + RS SP P+
Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA-PEKKEK 219
Query: 222 SPSRVPFSSGQHSTQSFPPSLM--SKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQS 279
+P +P + S + PS+ + ++ +L+ P P + S E E ++
Sbjct: 220 TP-ELP----EPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT 274
Query: 280 HGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCK 339
S + K S+ T+ + PS S P P +
Sbjct: 275 RPRSRSRSKSRSR---TRSRSPSHTRPRRRHRSRS-----RSYSPRRRPSPRRRPSPRRR 326
Query: 340 TEPSKFPFPTKESQQSNFGTGEQKRYN-----PSKTSNGHQSKSMLKDDLKLSSSEDSDG 394
T P + P P ++S ++R + S +S+ +S+S K K +SS
Sbjct: 327 TPPRRMP-PPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385
Query: 395 EQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEAN 454
+ P S P+ + + S+ + S S + + +
Sbjct: 386 RRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGT 445
Query: 455 EPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNS 514
E +S SP P+P L++ K ++ DS + + Y+++ ++
Sbjct: 446 EKRESPSPAPKPRKVE-------LSESEEDKGGKMAAADS-VQQRRQYRRQNQQ------ 491
Query: 515 YTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAA 574
+S +SS+ R ++ K E GR R+ SP++S S + P+K +K
Sbjct: 492 --SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPS---------PRKRQKET 540
Query: 575 AEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTS 634
+ PRG + + S P +R + + + P ++ PR + S
Sbjct: 541 S--PRGRRR--------RSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRS 590
Query: 635 KSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFS 694
S ++ I+ S S + + P P P+ +P P ++R+
Sbjct: 591 PSPRRYSPPIQRRYSPSPPPKRRTASP----PPPPKRRASPSPPP---------KRRVSH 637
Query: 695 PMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQK 754
K+ SP+++ R P + + P + +E P+ K++ P R Q
Sbjct: 638 SPPPKQRSSPVTK--RRSPSL--SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQT 693
Query: 755 QASEKVSNKGKRKHKNEDDN---------RASESKKPKTEDKNSAGHKPSSNRESSKQS- 804
+S +G + R S + +PK K ++ S R SS +S
Sbjct: 694 SSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSV 753
Query: 805 ------AAKEKDLLPSPAGPVPSKDPKTEHGSR---KRTISQSSSLKSSSNSNKETSGSS 855
AAK+ P+P PV S+ P T K+ S + S NS++E G
Sbjct: 754 SGSPEPAAKKP---PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKK 810
Query: 856 KNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSS 887
K K KK + K K KEKA ++++
Sbjct: 811 KKKKKDKKHKK-DKKHKKHKKHKKEKAVAAAA 841
Score = 73.6 bits (179), Expect = 1e-12
Identities = 111/526 (21%), Positives = 175/526 (33%), Gaps = 60/526 (11%)
Query: 442 SESESSSSDSEANEPSQSASPEP-EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQ 500
S E++S+ P PEP EP P + + K P S + S S
Sbjct: 234 SVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSP 293
Query: 501 GYKK-EGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQ------- 552
+ + R + SY+ P +P R + + R +SP +
Sbjct: 294 SHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA 353
Query: 553 -------SDSTTQRRTVGKKQPKKAE----KAAAEEPRGGLKIESETPVDLASSMPSSRH 601
S S+++ R+ KK PK+ K P P A+ P +RH
Sbjct: 354 SLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRH 413
Query: 602 KAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPP 661
+ S + + S S R + + K+K T K S S+S+E
Sbjct: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEE------ 467
Query: 662 SSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLN 721
+ SV++ + RQ S + S +D P +
Sbjct: 468 --------DKGGKMAAADSVQQRRQYRRQNQQSSSDS----GSSSSSEDERPKRSHVKNG 515
Query: 722 LLTR------------IPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK 769
+ R P K KET P+G ++ P ++ S + +R+
Sbjct: 516 EVGRRRRHSPSRSASPSPRKRQKETS-PRGRRRRSPSPPPTRRRRSPSPAPPPR-RRRTP 573
Query: 770 NEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSP-----AGPVPSKDP 824
R + S P+ + + P R S K + P P A P P
Sbjct: 574 TPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKR 633
Query: 825 KTEHG-SRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAP 883
+ H K+ S + +S S S+K GSS + S+ + K S S + +AP
Sbjct: 634 RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSP--RPRAP 691
Query: 884 SSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNA 929
+SS+ PP SS RR R E KK+K A
Sbjct: 692 QTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAA 737
Score = 70.5 bits (171), Expect = 9e-12
Identities = 163/774 (21%), Positives = 253/774 (32%), Gaps = 108/774 (13%)
Query: 84 PSADEKSNPNFFEQRHGGSHQSSKWTPV-GPAPSTSQSQKRSSGLQSGHSSQRTSAGSSS 142
PS +S+P E++ S T P+P+ + +K + + S ++
Sbjct: 180 PSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEAT 239
Query: 143 GTNSSGQ-------RHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHS 195
T+ + +E S K+ + S+SRS S + ++ S ++
Sbjct: 240 STSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPR 299
Query: 196 RSHGNDHHSKEHQRSKSP--RDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKP 253
R H + S +R SP R P R+P PP +S S
Sbjct: 300 RRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMP-----------PPPRHRRSRS----- 343
Query: 254 TAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDV 313
P+ + LS SS S + KP + K ++ L SAS
Sbjct: 344 -----PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRK--TRRLSPSASP-- 394
Query: 314 SCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTS-- 371
H PP T P KT S P QQSN + +P +TS
Sbjct: 395 -------PRRRHRPSPPAT---PPPKTRHSPTP------QQSNRTRKSRVSVSPGRTSGK 438
Query: 372 ----NGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDD 427
G + + K E S+ E+D M + ++
Sbjct: 439 VTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ-------Q 491
Query: 428 SSSHSGSESSSGSDSESESSSSDSEA-----NEPSQSASPEPEPPPTNKWQLDNWLNKVN 482
SSS SGS SSS + S + E + PS+SASP P K Q +
Sbjct: 492 SSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP-----RKRQKETSPRGRR 546
Query: 483 PHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSES 542
SP + PS + R S P S +P R S IQ+
Sbjct: 547 RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSP 606
Query: 543 GRGRQKSPAQSDSTTQRRTVGKKQPK-KAEKAAAEEPRGGLKIESETPVDLASSMPSSRH 601
++ A +RR PK + + + R + +P + S
Sbjct: 607 SPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP 666
Query: 602 KAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPP 661
+T+ +R P K SPRP A + TS S R + S P
Sbjct: 667 SRSTREARSPQPNKRHSPSPRPRAPQ-----TSSSPPPVRR-------GASSSPQRRQSP 714
Query: 662 SSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLN 721
S T +RTP +P +++ S SP + + S S P K
Sbjct: 715 SPSTRPIRRVSRTP-EPKKIKKAAS------PSPQSVRRVSSSRSVSGSPEPAAKK---- 763
Query: 722 LLTRIPGKPYKETEPPKGEKKNVPEKHTR------EAQKQASEKVSNKGKRKHKNEDDNR 775
P P + P VP K + + + ++ K K+K K++ +
Sbjct: 764 --PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKK 821
Query: 776 ASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSP--AGPVPSKDPKTE 827
+ KK K K A ++ + AA L A P P K+ ++E
Sbjct: 822 DKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESE 875
Score = 56.6 bits (135), Expect = 1e-07
Identities = 79/375 (21%), Positives = 135/375 (36%), Gaps = 55/375 (14%)
Query: 565 KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKS-SPRP 623
K+ K++ + E R + +S +P S P R + + SR P + +S+S SP P
Sbjct: 156 KEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSH-SRSPRHRTKSRSPSPAP 214
Query: 624 TAEKKKYKSTSKSSQKSREIIETDTSSSD---SDESESLP----PSSQTPKYPESNRTPV 676
++K + S + ++ TS+SD + E +P PS + E +
Sbjct: 215 EKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT 274
Query: 677 KPSSVEEEDSFFRQRMFSPMEEK---------ELLSPLSEPDDRYPLIVKIDLNLLTRIP 727
+P S S R R SP + SP P R + R P
Sbjct: 275 RPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPR------RRTP 328
Query: 728 GKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDK 787
P + PP+ + P + R + S S+ + +S S+ P +
Sbjct: 329 --PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS-----------SSSSRSRSPPKKPP 375
Query: 788 NSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSK-----DPKTEHGSRKRTISQSSSLK 842
P R S ++ + PSP P K P+ + +RK +S S
Sbjct: 376 KRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRT 435
Query: 843 SSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSS-------------SSNC 889
S + + + ++ S K +K E S K K A S SS+
Sbjct: 436 SGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSD 495
Query: 890 PPSAPTLDSSKPRRT 904
S+ + + +P+R+
Sbjct: 496 SGSSSSSEDERPKRS 510
Score = 55.5 bits (132), Expect = 3e-07
Identities = 65/290 (22%), Positives = 123/290 (42%), Gaps = 24/290 (8%)
Query: 626 EKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNR--TPV----KPS 679
E++K S K + + + + SS S P + + P R +PV K S
Sbjct: 137 EQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRS 196
Query: 680 SVEEEDSFFRQRMFSPMEEKELLSP-LSEPDDRY--PLIVKI-DLNLLTRIPGKPYKETE 735
+ R SP EK+ +P L EP + P + + + + ++P KP E
Sbjct: 197 HSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVP-KPEPIPE 255
Query: 736 PPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPS 795
P K+ PEK++++ +++ + ++ + K ++ +R+ +P+ + S S
Sbjct: 256 P----KEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHR-SRSRSYS 310
Query: 796 SNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSS 855
R S + + P P P + ++ R+R + SS S +S SS
Sbjct: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRR--------RRSSASLSGSSSSS 362
Query: 856 KNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTK 905
+S S S KK +TSS ++ + +PS+S P+ ++ P +T+
Sbjct: 363 SSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTR 412
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 85.1 bits (209), Expect = 4e-16
Identities = 176/876 (20%), Positives = 307/876 (35%), Gaps = 82/876 (9%)
Query: 77 IPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKR---SSGLQSGHS- 132
+ PT PPS+ + P+ G S T P P + K+ S + HS
Sbjct: 66 VHNPTSPPSSKKAPPPS------GASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSV 119
Query: 133 --SQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKP------ 184
+Q +S+ SSS ++SS R + S N++ + +K ++ K+R+ P
Sbjct: 120 SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD 179
Query: 185 QAVSSLNSSHSRSHGNDHHSKEHQR-SKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLM 243
+A S L++ + D + +H + S SP+ A +P P T +
Sbjct: 180 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTV 237
Query: 244 SKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQ 303
+K ++ K T + E K +S + S +L P+SK L P+
Sbjct: 238 NKETTVETKETTTTNKQTSTDGKE-KTTSAKETQSIEKTSAKDLAPTSKV----LAKPTP 292
Query: 304 PLDASASGDVSCVDEILKEMTHSWP--PPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGE 361
+ + G KE T + P P T P T P KE + +
Sbjct: 293 KAETTTKGPALTTP---KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 349
Query: 362 QKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRS-TPGSNSEPSHHN-SE 419
P+ T+ + + K+ ++ E + T P+ P + +P+ E
Sbjct: 350 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 409
Query: 420 GADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP-EPPPTNKWQLDNWL 478
A + + + + E + + + ++ + P + A P EP PT +
Sbjct: 410 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469
Query: 479 NKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTD-------------TSGPKETS 525
K P +P + S+ KE T ++ T + PKE +
Sbjct: 470 TK-EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 528
Query: 526 SATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIE 585
TP + + T K E K PA + + T K+ K A P K+
Sbjct: 529 PTTPKKPAPTTPK--EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKKLT 584
Query: 586 SETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIE 645
TP LA + P + T P +E P PT ++ +T K++ +
Sbjct: 585 PTTPEKLAPTTP-EKPAPTTPEELAPTTPEE----PTPTTPEEPAPTTPKAAAPNTPKEP 639
Query: 646 TDTSSSDSDESESLPPSSQTPKYPESNRTP--VKPSSVEEEDSFFRQ----RMFSPMEEK 699
T+ + + P+ TPK + TP P++++E + + +P K
Sbjct: 640 APTTPKEPAPTTPKEPAPTTPK-ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 698
Query: 700 ELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK 759
E S + D P K + P P EP K +E +K
Sbjct: 699 EPTS--TTCDKPAPTTPKGTAPTTPKEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 755
Query: 760 VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSP---- 815
+ K + + K T K +A P ++ + A P P
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 815
Query: 816 -AGPVPSKDPKTEHGSRKRT---ISQSSSLKSSSNSNKE-------TSGSSKNSSSTSKQ 864
+ P +K+P T H S + +S + K+ NS KE T ++K +T+ +
Sbjct: 816 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 875
Query: 865 KKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK 900
KT + ++ E AP + + SK
Sbjct: 876 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 911
Score = 67.0 bits (162), Expect = 1e-10
Identities = 149/845 (17%), Positives = 299/845 (35%), Gaps = 65/845 (7%)
Query: 78 PKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTS 137
P+P++PP++D + + + ++ + T ST +K +S ++ S ++TS
Sbjct: 219 PRPSLPPNSDTSKETSLTVNKET-TVETKETTTTNKQTSTDGKEKTTSAKET-QSIEKTS 276
Query: 138 AGSSSGTNS--SGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHS 195
A + T+ + E+ + + K + + S++P +P + ++ +
Sbjct: 277 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 336
Query: 196 RSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTA 255
+K + P + P +T+ P +KS K A
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-PAPTTTKSAPTTPKEPA 395
Query: 256 YVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSC 315
P +P ++ + + T P A TK P+ P + + +
Sbjct: 396 PTTPK------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 449
Query: 316 VDEILKEMTHSWP----------PPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRY 365
KE + P P T P T P TKE + +
Sbjct: 450 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 509
Query: 366 NPSKTSNGHQSKSMLKDDLKLSSSEDSDG--EQDCDKTMPRSTPGSNSEPSHHN-SEGAD 422
PS T+ + + K+ + + + ++ T P + +P+ E A
Sbjct: 510 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 569
Query: 423 NSRDDSSSHSGSESSSGSDSESESSSSDSEA-NEPSQSASPEPEPP-PTNKWQLDNWLNK 480
+ +++ + + + + + ++ + A P + A PE P PT +
Sbjct: 570 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE------- 622
Query: 481 VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS 540
P +P ++ N P T + PKET+ TP + T K
Sbjct: 623 --PAPTTPKAAAP-NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 679
Query: 541 ESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSR 600
++ +P + TT + +K A P+G TP + A + P
Sbjct: 680 APTTPKKPAPKELAPTTTKEPTSTT----CDKPAPTTPKG---TAPTTPKEPAPTTPKEP 732
Query: 601 HKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLP 660
KG+ +K+ + ++P+ A K+ +T+K + T+ ++ +
Sbjct: 733 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 792
Query: 661 PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYP-LIVKID 719
P+ TPK P + TP P E S +P KE + PD+ P L +
Sbjct: 793 PAPTTPKKP-APTTPETPPPTTSEVS-------TPTTTKEPTTIHKSPDESTPELSAEPT 844
Query: 720 LNLLTRIPGKP-YKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASE 778
L P +P T+ P K PE T A +K + + R
Sbjct: 845 PKALENSPKEPGVPTTKTPAATK---PEMTT-----TAKDKTTERDLRTTPETTTAAPKM 896
Query: 779 SKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQS 838
+K+ T + + K ++ +++ ++ +D P + + + + K+TI+ +
Sbjct: 897 TKETATTTEKTTESKITAT--TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 954
Query: 839 SSLKSSSNSNKETSGSSKNSSSTSK-QKKTEG-KTSSSSKEVKEKAPSSSSNCPPSAPTL 896
+ + K ++ + ++T K QK T+ K +S+K+ K P+ +
Sbjct: 955 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKM 1014
Query: 897 DSSKP 901
S+ P
Sbjct: 1015 TSTMP 1019
Score = 35.4 bits (80), Expect = 0.32
Identities = 44/242 (18%), Positives = 84/242 (34%), Gaps = 62/242 (25%)
Query: 725 RIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKG-------------------- 764
R P P K+ E + + E+H+ +++S S+
Sbjct: 94 RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANREL 153
Query: 765 --KRKHKNEDDNRASESKKPKTEDKNSAGH----------KPSSNRESSKQSAAKEKDLL 812
K K K+ NR + PK + AG P ++ + + K
Sbjct: 154 QKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT 213
Query: 813 PSPAGPVPSKDPKTEHGSRKR-TISQSSSL--KSSSNSNKETSGSSKNSSSTSKQKKTEG 869
P P PS P ++ T+++ +++ K ++ +NK+TS K ++++K+ ++
Sbjct: 214 AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 273
Query: 870 KTS---------------------------SSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902
KTS ++ KE P ++ P PT + K
Sbjct: 274 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 333
Query: 903 RT 904
T
Sbjct: 334 PT 335
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 85.1 bits (209), Expect = 4e-16
Identities = 176/876 (20%), Positives = 307/876 (35%), Gaps = 82/876 (9%)
Query: 77 IPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKR---SSGLQSGHS- 132
+ PT PPS+ + P+ G S T P P + K+ S + HS
Sbjct: 107 VHNPTSPPSSKKAPPPS------GASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSV 160
Query: 133 --SQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKP------ 184
+Q +S+ SSS ++SS R + S N++ + +K ++ K+R+ P
Sbjct: 161 SENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD 220
Query: 185 QAVSSLNSSHSRSHGNDHHSKEHQR-SKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLM 243
+A S L++ + D + +H + S SP+ A +P P T +
Sbjct: 221 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTV 278
Query: 244 SKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQ 303
+K ++ K T + E K +S + S +L P+SK L P+
Sbjct: 279 NKETTVETKETTTTNKQTSTDGKE-KTTSAKETQSIEKTSAKDLAPTSKV----LAKPTP 333
Query: 304 PLDASASGDVSCVDEILKEMTHSWP--PPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGE 361
+ + G KE T + P P T P T P KE + +
Sbjct: 334 KAETTTKGPALTTP---KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP 390
Query: 362 QKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRS-TPGSNSEPSHHN-SE 419
P+ T+ + + K+ ++ E + T P+ P + +P+ E
Sbjct: 391 TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKE 450
Query: 420 GADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEP-EPPPTNKWQLDNWL 478
A + + + + E + + + ++ + P + A P EP PT +
Sbjct: 451 PAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510
Query: 479 NKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTD-------------TSGPKETS 525
K P +P + S+ KE T ++ T + PKE +
Sbjct: 511 TK-EPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 569
Query: 526 SATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIE 585
TP + + T K E K PA + + T K+ K A P K+
Sbjct: 570 PTTPKKPAPTTPK--EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA--PTTPKKLT 625
Query: 586 SETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIE 645
TP LA + P + T P +E P PT ++ +T K++ +
Sbjct: 626 PTTPEKLAPTTP-EKPAPTTPEELAPTTPEE----PTPTTPEEPAPTTPKAAAPNTPKEP 680
Query: 646 TDTSSSDSDESESLPPSSQTPKYPESNRTP--VKPSSVEEEDSFFRQ----RMFSPMEEK 699
T+ + + P+ TPK + TP P++++E + + +P K
Sbjct: 681 APTTPKEPAPTTPKEPAPTTPK-ETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 739
Query: 700 ELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK 759
E S + D P K + P P EP K +E +K
Sbjct: 740 EPTS--TTCDKPAPTTPKGTAPTTPKEPA-PTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 796
Query: 760 VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSP---- 815
+ K + + K T K +A P ++ + A P P
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 856
Query: 816 -AGPVPSKDPKTEHGSRKRT---ISQSSSLKSSSNSNKE-------TSGSSKNSSSTSKQ 864
+ P +K+P T H S + +S + K+ NS KE T ++K +T+ +
Sbjct: 857 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 916
Query: 865 KKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK 900
KT + ++ E AP + + SK
Sbjct: 917 DKTTERDLRTTPETTTAAPKMTKETATTTEKTTESK 952
Score = 67.0 bits (162), Expect = 1e-10
Identities = 149/845 (17%), Positives = 299/845 (35%), Gaps = 65/845 (7%)
Query: 78 PKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTS 137
P+P++PP++D + + + ++ + T ST +K +S ++ S ++TS
Sbjct: 260 PRPSLPPNSDTSKETSLTVNKET-TVETKETTTTNKQTSTDGKEKTTSAKET-QSIEKTS 317
Query: 138 AGSSSGTNS--SGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHS 195
A + T+ + E+ + + K + + S++P +P + ++ +
Sbjct: 318 AKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTT 377
Query: 196 RSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTA 255
+K + P + P +T+ P +KS K A
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-PAPTTTKSAPTTPKEPA 436
Query: 256 YVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSC 315
P +P ++ + + T P A TK P+ P + + +
Sbjct: 437 PTTPK------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP 490
Query: 316 VDEILKEMTHSWP----------PPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRY 365
KE + P P T P T P TKE + +
Sbjct: 491 APTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 550
Query: 366 NPSKTSNGHQSKSMLKDDLKLSSSEDSDG--EQDCDKTMPRSTPGSNSEPSHHN-SEGAD 422
PS T+ + + K+ + + + ++ T P + +P+ E A
Sbjct: 551 EPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAP 610
Query: 423 NSRDDSSSHSGSESSSGSDSESESSSSDSEA-NEPSQSASPEPEPP-PTNKWQLDNWLNK 480
+ +++ + + + + + ++ + A P + A PE P PT +
Sbjct: 611 TTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEE------- 663
Query: 481 VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGS 540
P +P ++ N P T + PKET+ TP + T K
Sbjct: 664 --PAPTTPKAAAP-NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEP 720
Query: 541 ESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSR 600
++ +P + TT + +K A P+G TP + A + P
Sbjct: 721 APTTPKKPAPKELAPTTTKEPTSTT----CDKPAPTTPKG---TAPTTPKEPAPTTPKEP 773
Query: 601 HKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLP 660
KG+ +K+ + ++P+ A K+ +T+K + T+ ++ +
Sbjct: 774 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 833
Query: 661 PSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYP-LIVKID 719
P+ TPK P + TP P E S +P KE + PD+ P L +
Sbjct: 834 PAPTTPKKP-APTTPETPPPTTSEVS-------TPTTTKEPTTIHKSPDESTPELSAEPT 885
Query: 720 LNLLTRIPGKP-YKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASE 778
L P +P T+ P K PE T A +K + + R
Sbjct: 886 PKALENSPKEPGVPTTKTPAATK---PEMTT-----TAKDKTTERDLRTTPETTTAAPKM 937
Query: 779 SKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQS 838
+K+ T + + K ++ +++ ++ +D P + + + + K+TI+ +
Sbjct: 938 TKETATTTEKTTESKITAT--TTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 995
Query: 839 SSLKSSSNSNKETSGSSKNSSSTSK-QKKTEG-KTSSSSKEVKEKAPSSSSNCPPSAPTL 896
+ + K ++ + ++T K QK T+ K +S+K+ K P+ +
Sbjct: 996 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKM 1055
Query: 897 DSSKP 901
S+ P
Sbjct: 1056 TSTMP 1060
Score = 35.4 bits (80), Expect = 0.32
Identities = 44/242 (18%), Positives = 84/242 (34%), Gaps = 62/242 (25%)
Query: 725 RIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKG-------------------- 764
R P P K+ E + + E+H+ +++S S+
Sbjct: 135 RSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANREL 194
Query: 765 --KRKHKNEDDNRASESKKPKTEDKNSAGH----------KPSSNRESSKQSAAKEKDLL 812
K K K+ NR + PK + AG P ++ + + K
Sbjct: 195 QKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITT 254
Query: 813 PSPAGPVPSKDPKTEHGSRKR-TISQSSSL--KSSSNSNKETSGSSKNSSSTSKQKKTEG 869
P P PS P ++ T+++ +++ K ++ +NK+TS K ++++K+ ++
Sbjct: 255 AKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIE 314
Query: 870 KTS---------------------------SSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902
KTS ++ KE P ++ P PT + K
Sbjct: 315 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 374
Query: 903 RT 904
T
Sbjct: 375 PT 376
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 84.3 bits (207), Expect = 6e-16
Identities = 181/1031 (17%), Positives = 378/1031 (36%), Gaps = 116/1031 (11%)
Query: 37 EPYKVTSKEDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFE 96
E + T DKL ++ +++ I + + +A P +A+E + P+ E
Sbjct: 250 EDSRTTVASDKLLTKTTK------NIQETISANELTQSLAEPTEHGGRTANENNTPSPAE 303
Query: 97 QRHGGSHQSSKWTPVGPAPSTSQSQK----RSSGLQSGHSSQRTSAGSSSGT---NSSGQ 149
+++ T + PA ++ ++ +G + R + + T +
Sbjct: 304 PTENRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTE 363
Query: 150 RHDRESYNNSGSSSRKKGQHGSEHSKSRSS-SPGKPQA----------VSSLNSSHSRSH 198
+R + N+ S + +HG + ++ SP +P ++ +S+ S H
Sbjct: 364 HGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEH 423
Query: 199 GNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPT-AYV 257
G + SP +P N + ++ +++T S ++ + +K T + V
Sbjct: 424 GERTPLANENTTPSPAEPTENRER------TANENTTPSPAGPTENRETTANEKTTLSPV 477
Query: 258 RPMDGQESMEPKLSSEHYSSQSHGNSMT----ELKPSSKA----HLTKLKIPSQPLDASA 309
P + +E+ + ++ + + T E SS A H + + ++ S
Sbjct: 478 EPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSP 537
Query: 310 SGDVSCVDEILKEMTHSWP--PPLTAIHTPC---KTEPSKFPFPTKESQQSNFGTGEQKR 364
+ + E T P P TP KT PS PT+ Q++ F +K
Sbjct: 538 AEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPS-LAEPTENGQRTPFAN--EKT 594
Query: 365 YNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS 424
+ S H+ ++ L ++ S ++ ++ ++T +T S + P+ + A+
Sbjct: 595 TSSSAEPTEHEERTPLANENTTPSP--AEPTENRERTANENTTPSPAGPTENREMTANEK 652
Query: 425 RD-------DSSSHSGSESSSGSDSE-SESSSSDSEANEPSQSASPEP-----EPPPTNK 471
++ + +E ++ S +E +E+ ANE + S+S EP P N+
Sbjct: 653 TTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANE 712
Query: 472 WQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGR 531
+ L+ P + ++ + P + N+ + P E TP
Sbjct: 713 ---NTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLA 769
Query: 532 DSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVD 591
+ KT +E +++P ++ TT + ++ A + +P +
Sbjct: 770 NEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANEN--------TTSSPAE 821
Query: 592 LASSMPSSRHKAATKGSRKPNIKKES----KSSPRPT--AEKKKYKSTSKSSQKSREIIE 645
+ + ++ T+ +P +ES K++P P E +++ + ++ E E
Sbjct: 822 PTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTE 881
Query: 646 TDTSSSDSDESESLPPSSQTPKYPESNRTP-----VKPSSVEEEDSFFRQRMFSPMEEKE 700
+ + ++E +L P+ T RTP PSS E + R +P+ +
Sbjct: 882 HEEMTPLANEKTTLSPAEPT---ENGERTPFTNEKTTPSSAEPTEHGER----TPLANEI 934
Query: 701 LLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQA--SE 758
+EP + I T P KP + E E E ++ +
Sbjct: 935 TTPSRAEPTEHGERIAN---EKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLAN 991
Query: 759 KVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAK---EKDLLPSP 815
+ + + + A+E P + G + S E + S AK +++ PS
Sbjct: 992 ENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHEEMTPSA 1051
Query: 816 -AGPVPSKDPKTEHGSRKRTISQSSSLK---SSSNSNKETSGSSKNSSSTSKQKKTEGKT 871
PS TEHG + ++ +L + + K TS + K + S +K + +T
Sbjct: 1052 NENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERT 1111
Query: 872 SSSSKEVKEKAPSS--------SSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAK 923
+S + ++ A S S+N AP +RT L + + + +
Sbjct: 1112 TSPNDKITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPE 1171
Query: 924 KLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKL 983
K + + EK Y + + + + E+ + +ET+ +
Sbjct: 1172 KTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETI-----KAPV 1226
Query: 984 KNYLAPDATAA 994
K+ P+ TAA
Sbjct: 1227 KSTENPEKTAA 1237
Score = 72.0 bits (175), Expect = 3e-12
Identities = 143/795 (17%), Positives = 281/795 (35%), Gaps = 112/795 (14%)
Query: 159 SGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGND-----------HHSKEH 207
+G+++ ++ Q E S S P P V S+ H H H K H
Sbjct: 27 AGATTFQEYQKTGELSTSDHIFPLTPGLVYSIPFDHIVLHSGQRPPELPKSTEIHEQKRH 86
Query: 208 QRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESME 267
+ P S+ PP+ S+ NS Q +R Q S++
Sbjct: 87 CNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPT--SEENSSNQGKDPMIR---NQRSVD 141
Query: 268 PKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKI-----------PSQPLDASASGDVSCV 316
P S+ + +S G P SK + K +PL+ S S
Sbjct: 142 PADSTTTHK-ESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMS------ 194
Query: 317 DEILKEMTHSWPPPLTAIHTP--CKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGH 374
L + + S T+ H +T+ FP K + S T + P ++
Sbjct: 195 --TLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASK--TTYKTTGTPEESEKTE 250
Query: 375 QSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGS 434
S++ + D L+ + + E + +S +EP+ H A+ + S +
Sbjct: 251 DSRTTVASDKLLTKTTKNIQETISANELTQSL----AEPTEHGGRTANENNTPSPAEPTE 306
Query: 435 ESSSGSDSESESSSSDSEANEP---SQSASPEPEPPPTNKWQLDN---WLNKVNPHKVSP 488
++ + S ++ N +++ +P P P N+ N L P +
Sbjct: 307 NRERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTEHGE 366
Query: 489 ASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQK 548
++ ++ PS + G N+ + P E TP + KT +ES ++
Sbjct: 367 RTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGER 426
Query: 549 SPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS 608
+P +++TT P AE E R + + +P + ++ ++ T
Sbjct: 427 TPLANENTT---------PSPAEPTENRE-RTANENTTPSPAGPTENRETTANEKTTLSP 476
Query: 609 RKPNIKKES----KSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQ 664
+P +E+ K++P P + + T +++K+ T +S+ ++ E P +++
Sbjct: 477 VEPTENRETTANEKTTPSPAEPTENGQRTPFANEKT-----TSSSAEPTEHGERTPLANE 531
Query: 665 ----TPKYPESNR-----TPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLI 715
+P P NR PS E ++ R +P+ ++ L+EP +
Sbjct: 532 NTTPSPAEPTENRERTANEKTTPSPAEPTENGDR----TPLANEKTTPSLAEPTENG--- 584
Query: 716 VKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNR 775
R P K T + E+ T A + + + + + + ++N
Sbjct: 585 --------QRTPFANEKTTS--SSAEPTEHEERTPLANENTTPSPAEPTENRERTANENT 634
Query: 776 ASESKKPKTEDKNSAGHK-------PSSNRESSKQSAAKEKDLLPSPAG---------PV 819
P + +A K P+ NRE + P+ G
Sbjct: 635 TPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTT 694
Query: 820 PSKDPKTEHGSRKRTISQSSSLK-SSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV 878
S TEHG R +++++L + N+E + + K + ++ + +T++ +
Sbjct: 695 SSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTP 754
Query: 879 KEKAPSSSSNCPPSA 893
P+ + + P A
Sbjct: 755 SPAQPTENGDRTPLA 769
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 82.4 bits (202), Expect = 2e-15
Identities = 178/856 (20%), Positives = 321/856 (37%), Gaps = 168/856 (19%)
Query: 105 SSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSR 164
SS+W S SQ+ S +G+ S ++A SG + ++ + + G
Sbjct: 394 SSRWD------ERSLSQRSRSWSYNGYYSDLSTA-RHSGHHKKRRKEKKVKHKKKG---- 442
Query: 165 KKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSR-------------SHGNDHHSKEHQRSK 211
KK +H H +++ P + S SS R S + HHS + SK
Sbjct: 443 KKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSHHSSKRDWSK 502
Query: 212 SPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLS 271
S +D ++ SR + S HS QS+ S S + K +++ R +
Sbjct: 503 SDKDVQSSLTHSSRDSYRSKSHS-QSY--SRGSSRSRTASKSSSHSR---------SRSK 550
Query: 272 SEHYSSQSHGNSMTELKPSSKAHLTKLK-IPSQPLDASASGDVSCVDEILKEMTHSWPP- 329
S S H ++ + + L++ K + ++PL A+ + + + V + + + P
Sbjct: 551 SRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVV--VQPVVAENIPVI 608
Query: 330 PLTAIHTPCKTEPSKFPF-PTKESQQSNFGTGEQKRYNPSKTSN-----GHQSKSMLKDD 383
PL+ P + +P + P+ P+ E Q E K +KT++ S + +K+
Sbjct: 609 PLSDSPPPSRWKPGQKPWKPSYERIQ------EMK----AKTTHLLPIQSTYSLANIKET 658
Query: 384 LKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSE 443
SS + + D++ +SE S + + SR S S++ S S + S S
Sbjct: 659 GSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSR 718
Query: 444 SESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYK 503
S S SS S + NK + H SS ++I S G +
Sbjct: 719 SRSPSSRSHSR------------------------NKYSDHSQCSRSSSYTSISSDDGRR 754
Query: 504 KEGREQGTGNSYTDTSGPKETSSA--------TPGRD-SKTIQKGSESGRGRQKSPAQSD 554
+ R + +G S K +SS+ GRD S ++K SES S
Sbjct: 755 AKRRLRSSGKK-NSVSHKKHSSSSEKTLHSKYVKGRDRSSCVRKYSESRSSLDYSSDSEQ 813
Query: 555 STTQRRTVGKKQPKKAEKAAA----EEPRGGLKIESETPVDLA---------------SS 595
S+ Q +++ K+ + E+ RG K +SE + S
Sbjct: 814 SSVQATQSAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGS 873
Query: 596 MPSSRHKAATKGSRKPN----IKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSS 651
P ++ A +K + N + K SK+ P+++K++ ++TS S + EI ++
Sbjct: 874 KPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTT 933
Query: 652 DSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDR 711
S + SLP + K SS + + + S E
Sbjct: 934 KSSTNTSLPDDNGAWK-----------SSKQRTSTSDSEGSCSNSENNR----------- 971
Query: 712 YPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNE 771
GKP K G K+N+ +HT K+ EK+ K +KHK
Sbjct: 972 ----------------GKPQKHKH---GSKENLKREHT----KKVKEKLKGKKDKKHKAP 1008
Query: 772 DDNRASESKKPKT--EDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHG 829
+A + P E++ +ES ++ ++ + + KTE
Sbjct: 1009 KRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNE-------TIKDNILKTEKS 1061
Query: 830 SRKRTISQSSSLKSSSNSNKETSGSSKNS-SSTSKQKKTEGKTSSSSKEVKEKAPSSSSN 888
S + + ++ SS+ ++ T SK S S T+ + + + V+E P+ +
Sbjct: 1062 SEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVED 1121
Query: 889 CPPSAPTLDSSKPRRT 904
+ ++ P R+
Sbjct: 1122 VLQTDDNMEICTPDRS 1137
Score = 73.9 bits (180), Expect = 8e-13
Identities = 186/970 (19%), Positives = 355/970 (36%), Gaps = 157/970 (16%)
Query: 4 EDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK 63
+ R+ + R+R ++ ++ + P+ EP + T M N + +
Sbjct: 550 KSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRAT------------MAQNENVVV 597
Query: 64 DFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPST-SQSQK 122
+ +IP + P PPS + + +K T + P ST S +
Sbjct: 598 QPVVAENIPVIPLSDSP--PPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANI 655
Query: 123 RSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPG 182
+ +G S + + ++ S T S ES S S S + + +++SRS +
Sbjct: 656 KETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASS 715
Query: 183 KPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSL 242
++ S + SHSR+ +DH S + D + R+ SSG+ ++ S
Sbjct: 716 HSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLR-SSGKKNSVSHKKHS 774
Query: 243 MSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPS 302
S ++ K YV+ D + + + S + L SS + + ++
Sbjct: 775 SSSEKTLHSK---YVKGRDRSSCV-----------RKYSESRSSLDYSSDSEQSSVQATQ 820
Query: 303 QPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQ 362
+ G + E TH+ Q+ N GE+
Sbjct: 821 SAQEKEKQGQM--------ERTHN-------------------------KQEKN--RGEE 845
Query: 363 KRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGAD 422
K + S+ H K LK++L SD ++ K ++ GS +
Sbjct: 846 K--SKSERECPHSKKRTLKENL-------SDHLRNGSKPKRKNYAGS-------KWDSES 889
Query: 423 NSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVN 482
NS D + +S ++S SD E ++SDSE S+ + + PT K
Sbjct: 890 NSERDVTKNSKNDSHPSSDKEEGEATSDSE----SEVSEIHIKVKPTTK----------- 934
Query: 483 PHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSES 542
SS ++++P G K +++ S +D+ G S G+ K + GS+
Sbjct: 935 -------SSTNTSLPDDNGAWKSSKQR---TSTSDSEGSCSNSENNRGKPQKH-KHGSKE 983
Query: 543 GRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK 602
R+ + + ++ K PK+ ++A +P E E +D S+ K
Sbjct: 984 NLKREHTKKVKEKLKGKKDKKHKAPKR-KQAFHWQPPLEFGEEEEEEIDDKQVTQESKEK 1042
Query: 603 AATKGSR--KPNIKKESKSSPRPTAEKKKYKSTSKSSQ---KSREIIETDTSSSDSDES- 656
++ + K NI K KSS + K + S K + ++ +++E+
Sbjct: 1043 KVSENNETIKDNILKTEKSSEEDLSGKHDTVTVSSDLDQFTKDDSKLSISPTALNTEENV 1102
Query: 657 ----------ESLPPSSQTPKYPESNR---TPVK--PSSVEEEDSFFRQRMFSPMEEKEL 701
ES+P + + N TP + P+ VEE R+ +P L
Sbjct: 1103 ACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRSSPAKVEETSPLGNARLDTPDINIVL 1162
Query: 702 LSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETE-----PPKGE---KKNVPEKHTREAQ 753
++ + ++ + +++ G+ K+ GE KK V EK
Sbjct: 1163 KQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLI 1222
Query: 754 KQASEKVSNKGKRKHKNEDDNRASESK--------KP---KTEDKNSAGHKPSSNRESSK 802
+ + + G N + A E K KP + E K+ +P S + +
Sbjct: 1223 DKKWKPLQGVGNLAAPNAATSSAVEVKVLTTVPEMKPQGLRIEIKSKNKVRPGSLFDEVR 1282
Query: 803 QSA-----AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKN 857
++A + ++ P D ++ SR R+ S++ S + + + S S
Sbjct: 1283 KTARLNRRPRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSR 1342
Query: 858 SSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFD----DRNY 913
SS++S + ++ ++ S + + S SS+ SS+ R +D R+Y
Sbjct: 1343 SSTSSYRSRSYSRSRSRGWYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSY 1402
Query: 914 SADHYLQEAK 923
+ D Y ++
Sbjct: 1403 TYDSYYSRSR 1412
Score = 64.3 bits (155), Expect = 6e-10
Identities = 157/685 (22%), Positives = 240/685 (35%), Gaps = 103/685 (15%)
Query: 361 EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEG 420
E+KR P+ S G S S + SS + + E+ + R S+ +
Sbjct: 186 EKKRKKPTH-SEGSDSSSNSSSSSESSSESELEHERSRRRKHKRRPKVKRSKKRRKEASS 244
Query: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPP-PTNKWQLDNWLN 479
++ R+ + + S +E S DS A PE PP P N++ L +
Sbjct: 245 SEEPRNKHAMNPKGHSERSDTNEKRSV--DSSAKREKPVVRPEEIPPVPENRFLLRRDMP 302
Query: 480 KVNPH------KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTD------TSGPKETSSA 527
V V+P S S G K +GR GT +T + + SS
Sbjct: 303 VVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGR--GTIRYHTPPRSRSCSESDDDDSSE 360
Query: 528 TPGRDSKTIQK----GSESGRGRQKSPAQSD---------STTQRRTVGKKQPKKAEKAA 574
TP + +Q+ SG K SD S +QR ++ +
Sbjct: 361 TPPHWKEEMQRLRAYRPPSGEKWSKGDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLST 420
Query: 575 AEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRK-----PNIKKESKSSPRPTAEK-K 628
A K E V +H K ++K P+ + SKSS R
Sbjct: 421 ARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCD 480
Query: 629 KYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPES-----------NRTPVK 677
+ +S+ SS S + D S SD D SL SS+ +S +RT K
Sbjct: 481 RERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASK 540
Query: 678 PSSVEEEDSFFRQRMFSPMEEKELLSP------LSE--PDDRYPLIVKIDLN-------- 721
SS S R S ++ SP LSE P PL + N
Sbjct: 541 SSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPV 600
Query: 722 LLTRIPGKPYKETEPPK----GEKKNVPEKHTREAQKQ--------------ASEKVSNK 763
+ IP P ++ PP G+K P + K A+ K +
Sbjct: 601 VAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGS 660
Query: 764 GKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGP-VPSK 822
HK E ++ + +S K D++S S +R S +S ++ S A S+
Sbjct: 661 SSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSR 720
Query: 823 DPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKA 882
P + SR + S +SSS TS SS + ++ ++ GK +S V K
Sbjct: 721 SPSSRSHSRNKYSDHSQCSRSSS----YTSISSDDGRRAKRRLRSSGKKNS----VSHKK 772
Query: 883 PSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADA--LSDRFEKAV 940
SSSS TL S + DR+ Y + L +++D+ S + ++
Sbjct: 773 HSSSSE-----KTLHSKYVKGR-----DRSSCVRKYSESRSSLDYSSDSEQSSVQATQSA 822
Query: 941 YYLDAVVSFIECGNALEKNAQESKS 965
+ N EKN E KS
Sbjct: 823 QEKEKQGQMERTHNKQEKNRGEEKS 847
Score = 62.0 bits (149), Expect = 3e-09
Identities = 122/598 (20%), Positives = 215/598 (35%), Gaps = 101/598 (16%)
Query: 349 TKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPG 408
+K S + + +++R + S + + H S S + S ++D ++ S+
Sbjct: 468 SKSSTRRMKSSCDRERSSRSSSLSSHHS----------SKRDWSKSDKDVQSSLTHSSRD 517
Query: 409 SNSEPSHHNS--EGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEP 466
S SH S G+ SR S S S S S S S S S+S + P ++AS E
Sbjct: 518 SYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRSSSKSGHRKRASKSPRKTASQLSEN 577
Query: 467 PPTNKWQLDNWLNKVNPHKVSPASSVDSNIP------SSQGYKKEGREQGTGNSYTDTSG 520
P L + + V P V NIP S + + ++ SY
Sbjct: 578 KPVKTEPLRATMAQNENVVVQPV--VAENIPVIPLSDSPPPSRWKPGQKPWKPSYERIQE 635
Query: 521 PK-ETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPR 579
K +T+ P + + ++ E+G + +S + + T K + +E + R
Sbjct: 636 MKAKTTHLLPIQSTYSLANIKETGSSSSYHKREKNSESDQSTYSKYSDRSSESSPRSRSR 695
Query: 580 GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQK 639
+ S+ SS + SR P+ + S++ KY S SQ
Sbjct: 696 SSRSRSYSRSYTRSRSLASSHSR-----SRSPSSRSHSRN---------KY---SDHSQC 738
Query: 640 SREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEK 699
SR T SS D ++ SS K +SV + S EK
Sbjct: 739 SRSSSYTSISSDDGRRAKRRLRSSG------------KKNSVSH-------KKHSSSSEK 779
Query: 700 ELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK 759
L S + DR + K + R ++E + ++ ++ Q + +
Sbjct: 780 TLHSKYVKGRDRSSCVRKYSES---RSSLDYSSDSEQSSVQATQSAQEKEKQGQMERTHN 836
Query: 760 VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPV 819
K + + K++ + SKK +T +N + H + ++ K A + D
Sbjct: 837 KQEKNRGEEKSKSERECPHSKK-RTLKENLSDHLRNGSKPKRKNYAGSKWD--------- 886
Query: 820 PSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVK 879
S SNS ++ + +SKN S S K+ TS S EV
Sbjct: 887 -----------------------SESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVS 923
Query: 880 E--------KAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNA 929
E S++++ P SSK R + + ++++ + +K KH +
Sbjct: 924 EIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGS 981
Score = 51.2 bits (121), Expect = 6e-06
Identities = 129/664 (19%), Positives = 227/664 (34%), Gaps = 108/664 (16%)
Query: 85 SADEKSNPNFFEQRHG------GSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSA 138
SA EK E+ H G +S + + + S L++G +R +
Sbjct: 821 SAQEKEKQGQMERTHNKQEKNRGEEKSKSERECPHSKKRTLKENLSDHLRNGSKPKRKNY 880
Query: 139 GSSSGTNSSGQRHD--RESYNNSGSSSRKKGQHGSEHSKSRSSS---PGKPQAVSSLNSS 193
S + S D + S N+S SS K+ + S+S S KP SS N+S
Sbjct: 881 AGSKWDSESNSERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTS 940
Query: 194 HSRSHGNDHHSKEHQRSK----SPRDPDANWDSPSRVPFSSGQH----STQSFPPSLMSK 245
+G SK+ + S + + N P + S ++ T+ L K
Sbjct: 941 LPDDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGK 1000
Query: 246 SNSMLQKPTA-----YVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKI 300
+ + P + P++ E E ++ + + +S ++E + K ++ K +
Sbjct: 1001 KDKKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEK 1060
Query: 301 PSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTG 360
S+ D S D V L + T K + PT + + N
Sbjct: 1061 SSEE-DLSGKHDTVTVSSDLDQFT--------------KDDSKLSISPTALNTEENVACL 1105
Query: 361 EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEG 420
+ ++ NG + D++++ + + RS+P E S +
Sbjct: 1106 QNIQHVEESVPNGVEDVLQTDDNMEICTPD-------------RSSPAKVEETSPLGNAR 1152
Query: 421 ADN-------SRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQ 473
D +D ++ H +E S SES + S SAS T K +
Sbjct: 1153 LDTPDINIVLKQDMATEHPQAEVVKQESSMSESKVLGEVGKQDSSSASLASAGESTGKKE 1212
Query: 474 LDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDS 533
+ + S + +D KK QG GN + TSSA +
Sbjct: 1213 VA---------EKSQINLID---------KKWKPLQGVGNLAAPNAA---TSSAVEVKVL 1251
Query: 534 KTIQKGSESG-----RGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESET 588
T+ + G + + K S R+T + + ++++++E +S++
Sbjct: 1252 TTVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESSSDEQTPSRDDDSQS 1311
Query: 589 PVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKS-------- 640
S SR K+ TK + S S R + Y+S S S +S
Sbjct: 1312 -----RSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSRSRGWYSRGR 1366
Query: 641 --------REIIETDTSSSDSDESESLPPSSQTPKYPESN--RTPVKPSSVEEEDSFFRQ 690
R TSS S S P S++ Y + S + DS+ R
Sbjct: 1367 TRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRSDSYHRG 1426
Query: 691 RMFS 694
R ++
Sbjct: 1427 RSYN 1430
Score = 45.4 bits (106), Expect = 3e-04
Identities = 126/670 (18%), Positives = 217/670 (32%), Gaps = 98/670 (14%)
Query: 437 SSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNI 496
S GSDS S SSSS ++E +L++ ++ HK P
Sbjct: 195 SEGSDSSSNSSSSSESSSES----------------ELEHERSRRRKHKRRPK------- 231
Query: 497 PSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDST 556
K+ + + KE SS+ R+ + S R DS+
Sbjct: 232 -----VKRSKKRR------------KEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSS 274
Query: 557 TQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKE 616
+R ++P + P + + PV A P A +KP++ K
Sbjct: 275 AKR-----EKPVVRPEEIPPVPENRFLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKS 329
Query: 617 SKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPV 676
+ K K + T + R S SD D+S PP K
Sbjct: 330 GR--------KIKGRGTIRYHTPPRS---RSCSESDDDDSSETPPHW---KEEMQRLRAY 375
Query: 677 KPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPG--KPYKET 734
+P S E+ ++ P + LS+ + R G K ++
Sbjct: 376 RPPSGEKWSK--GDKLSDPCSSRWDERSLSQRSRSWSYNGYYSDLSTARHSGHHKKRRKE 433
Query: 735 EPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASES-KKPKTEDKNSAGHK 793
+ K +KK +KH R ++ ++ + R S + ++ +S
Sbjct: 434 KKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKSSTRRMKSSCDRERSSRSSSLSSH 493
Query: 794 PSSNRESSKQSAAKEKDLLPSPAGPVPSKD---------------PKTEHGSRKRTISQS 838
SS R+ SK + L S SK K+ SR R+ S+S
Sbjct: 494 HSSKRDWSKSDKDVQSSLTHSSRDSYRSKSHSQSYSRGSSRSRTASKSSSHSRSRSKSRS 553
Query: 839 SSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDS 898
SS ++ + + S +K KTE ++ ++ + P P DS
Sbjct: 554 SSKSGHRKRASKSPRKTASQLSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDS 613
Query: 899 SKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEK 958
P R K S + + K H S + + S+ + EK
Sbjct: 614 PPPSRWKPGQKPWKPSYERIQEMKAKTTHLLPIQSTYSLANIKETGSSSSY----HKREK 669
Query: 959 NAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKK 1018
N++ +S + YS+ + +P + + R R S Y R L
Sbjct: 670 NSESDQSTYSKYSDR----------SSESSPRSRSRSSR-----SRSYSRSYTRSRSLAS 714
Query: 1019 ENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASA 1078
++ S + H +N Y++ S ++ K +SG +S + +
Sbjct: 715 SHSRSRSPSSRSHSRNKYSDHSQCSRSSSYTSISSDDGRRAKRRLRSSGKKNSVSHKKHS 774
Query: 1079 SGSSVTIPQK 1088
S S T+ K
Sbjct: 775 SSSEKTLHSK 784
Score = 38.9 bits (89), Expect = 0.029
Identities = 43/163 (26%), Positives = 70/163 (42%), Gaps = 15/163 (9%)
Query: 84 PSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSG 143
PS D+ S + S S+ + S S+S+ RSS S + S+ S S G
Sbjct: 1303 PSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSS--TSSYRSRSYSRSRSRG 1360
Query: 144 TNSSGQRHDRES----YNNSGSSSRKKGQHGS--EHSKSRS------SSPGKPQAVSSLN 191
S G+ R S Y + +SSR + + S HS+SRS S + ++ S +
Sbjct: 1361 WYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSRSRSYTYDSYYSRSRSRSRSQRS 1420
Query: 192 SSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHS 234
S+ R + S+ + S + D ++ S R P S ++S
Sbjct: 1421 DSYHRGRSYNRRSRSCRSYGSDSESDRSY-SHHRSPSESSRYS 1462
Score = 36.6 bits (83), Expect = 0.14
Identities = 43/171 (25%), Positives = 65/171 (38%), Gaps = 16/171 (9%)
Query: 113 PAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSE 172
P S S +++ S+ S S S R SY++S S SR
Sbjct: 1291 PRNQESSSDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRS 1350
Query: 173 HSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHS-KEHQRSKSPRDPDANWDSPSRVPFSSG 231
S SRS S G + +RS + + S K H+ S R +++D SR S
Sbjct: 1351 RSYSRSRSRG------WYSRGRTRSRSSSYRSYKSHRTSSRSRSRSSSYDPHSR----SR 1400
Query: 232 QHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGN 282
++ S+ S+S S Q+ +Y R G+ S Y S S +
Sbjct: 1401 SYTYDSY--YSRSRSRSRSQRSDSYHR---GRSYNRRSRSCRSYGSDSESD 1446
Score = 33.9 bits (76), Expect = 0.93
Identities = 29/136 (21%), Positives = 52/136 (38%), Gaps = 12/136 (8%)
Query: 756 ASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSP 815
A +V + G K+ D + KKP + + + SS+ ESS +S + +
Sbjct: 166 ADVRVIDCGVLATKSIKDVFEKKRKKPTHSEGSDSSSNSSSSSESSSESELEHE------ 219
Query: 816 AGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSS 875
+ + +H R + K +S+S + + + N S++ T K S S
Sbjct: 220 ------RSRRRKHKRRPKVKRSKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDS 273
Query: 876 KEVKEKAPSSSSNCPP 891
+EK PP
Sbjct: 274 SAKREKPVVRPEEIPP 289
>gi|50962882 G patch domain containing 8 [Homo sapiens]
Length = 1502
Score = 82.4 bits (202), Expect = 2e-15
Identities = 137/623 (21%), Positives = 225/623 (36%), Gaps = 92/623 (14%)
Query: 338 CKTEPSKFPF---PTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLK----DDLKLSSSE 390
CK +P+ FPF Q T K SK + + KS +K + + SE
Sbjct: 402 CKVKPN-FPFLLFMRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEKTVSE 460
Query: 391 DSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSG--SESSSGSDSESESSS 448
S+ ++ T P S PGS +E + G D S SHS SE+ + S+ +S
Sbjct: 461 VSEQPKETSMTEP-SEPGSKAEAK--KALGGDVSDQSLESHSQKVSETQMCESNSSKETS 517
Query: 449 SDSEANEPSQSASPEPEPPPTNKWQLDN-----WLNKVNPH-KVSPASSVDSNIPSSQGY 502
+ A + SQ P P D W +++ K P+ S N P +
Sbjct: 518 LATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCN-PLYFDF 576
Query: 503 K----KEGREQGTGNSYTDTSGPKE-TSSATPGRDSKTIQKGSE----SGRGRQKSPAQS 553
K K+ R +GT S K+ PG +K+ + G E S GR +PA
Sbjct: 577 KLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG 636
Query: 554 DSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNI 613
+ + + K++P + + E+ L + E +HK ++K RK
Sbjct: 637 SACSG---LNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHKKSSKHKRKHKA 693
Query: 614 KKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNR 673
E KSS + EK K K + +K++ D+ E PP S +P P R
Sbjct: 694 DTEEKSSKAESGEKSK-KRKKRKRKKNKSSAPADSERGPKPE----PPGSGSPAPPRRRR 748
Query: 674 TPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKE 733
++DS QR P EE G K+
Sbjct: 749 R-------AQDDS---QRRSLPAEE-----------------------------GSSGKK 769
Query: 734 TEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHK 793
E G +K E + +R+ + +R+S +P + D++S
Sbjct: 770 DEGGGGS-----SSQDHGGRKHKGELPPSSCQRRAGTKRSSRSSHRSQPSSGDEDSDDAS 824
Query: 794 PSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHG-SRKRTISQSSSLKSSSNSNKETS 852
+ S ++E++ +D +EH SR R+ + SS +SS S +S
Sbjct: 825 SHRLHQKSPSQYSEEEE----------EEDSGSEHSRSRSRSGRRHSSHRSSRRSYSSSS 874
Query: 853 GSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRN 912
+S + S S+Q+ + S + + S + S + +R K D +
Sbjct: 875 DASSDQSCYSRQRSYSDDSYSDYSDRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDD 934
Query: 913 YSADHYLQEAKKLKHNADALSDR 935
YS ++ H + R
Sbjct: 935 YSLSCSQSRSRSRSHTRERSRSR 957
Score = 68.6 bits (166), Expect = 3e-11
Identities = 146/691 (21%), Positives = 233/691 (33%), Gaps = 126/691 (18%)
Query: 84 PSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSG 143
PS NP +F+ + + + P S S+ GL G ++ G
Sbjct: 563 PSISYSCNPLYFDFKLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKI 622
Query: 144 TNSSGQRHDRESYNNSGSSSRKK---GQHGSEHSKSRSSSPGKPQAVSSLN--------- 191
SSG R D + ++ S K+ G HGSE + S P K + +
Sbjct: 623 VRSSGGRMDAPASGSACSGLNKQEPGGSHGSETEDTGRSLPSKKERSGKSHRHKKKKKHK 682
Query: 192 --SSHSRSHGND-----------HHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSF 238
S H R H D SK+ ++ K ++ + R P S
Sbjct: 683 KSSKHKRKHKADTEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPA 742
Query: 239 PPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHG--NSMTELKPSS--KAH 294
PP ++ Q+ + P + S + SSQ HG EL PSS +
Sbjct: 743 PPRRRRRAQDDSQRRSL---PAEEGSSGKKDEGGGGSSSQDHGGRKHKGELPPSSCQRRA 799
Query: 295 LTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQ 354
TK S +SGD D + H + PS++ ++E ++
Sbjct: 800 GTKRSSRSSHRSQPSSGDEDSDD--------------ASSHRLHQKSPSQY---SEEEEE 842
Query: 355 SNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDC---------------- 398
+ G+ ++ S++ +G + S SSS D+ +Q C
Sbjct: 843 EDSGS----EHSRSRSRSGRRHSSHRSSRRSYSSSSDASSDQSCYSRQRSYSDDSYSDYS 898
Query: 399 DKTMPRSTPGSNSEPS------HHNSEGADNSRDDSSSHSGSESSSGSDS---ESESSSS 449
D++ S +S+ S H + +S DD S S S+S S S S E S
Sbjct: 899 DRSRRHSKRSHDSDDSDYASSKHRSKRHKYSSSDDDYSLSCSQSRSRSRSHTRERSRSRG 958
Query: 450 DSEANEPSQSASPEPEPPPT-NKWQLDNWLNKVNPHKVSPASS----------------- 491
S ++ S+S S T + WQ ++ S
Sbjct: 959 RSRSSSCSRSRSKRRSRSTTAHSWQRSRSYSRDRSRSTRSPSQRSGSRKRSWGHESPEER 1018
Query: 492 -------VDSNIPSSQG--YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSES 542
+ S I SQ Y + GR +G G G + S AT G S+ G+
Sbjct: 1019 HSGRRDFIRSKIYRSQSPHYFRSGRGEGPGKK---DDGRGDDSKAT-GPPSQNSNIGTGR 1074
Query: 543 GRGRQKSPAQSDSTTQRRTVGK-------KQPKKAEKAAAEEPRGGLKIESETPVDLASS 595
G SP +S T + + K ++P +E+ A + G K++
Sbjct: 1075 GSEGDCSPEDKNSVTAKLLLEKIQSRKVERKPSVSEEVQATPNKAGPKLKDPPQGYFGPK 1134
Query: 596 MPSSRHK-------AATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDT 648
+P S +RKPN K E R E+++ T + S + +
Sbjct: 1135 LPPSLGNKPVLPLIGKLPATRKPNKKCEESGLER--GEEQEQSETEEGPPGSSDALFGHQ 1192
Query: 649 SSSDSDESESLPPSSQTPKYPESNRT-PVKP 678
S+ L P + K E+ PV P
Sbjct: 1193 FPSEETTGPLLDPPPEESKSGEATADHPVAP 1223
Score = 55.8 bits (133), Expect = 2e-07
Identities = 115/539 (21%), Positives = 200/539 (37%), Gaps = 54/539 (10%)
Query: 417 NSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSE-------ANEPSQSASPEPEPPPT 469
+ EG ++ +D+S+++SG+ +++ SE S+ N + +P
Sbjct: 224 DEEGGEDDKDESATNSGTGATASCGLGSEFSTDKGGPFTAVQITNTTGLAQAPGLASQGI 283
Query: 470 N---KWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS 526
+ K L L K+ S A + S K+ E+GT D + P E SS
Sbjct: 284 SFGIKNNLGTPLQKLGV-SFSFAKKAPVKLESIASVFKDHAEEGTSE---DGTKPDEKSS 339
Query: 527 ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK-KQPKKAEKAAAEEPR------ 579
G GS + G+++ D + T+ K K+ K+ E A A EP
Sbjct: 340 -DQGLQKVGDSDGSSNLDGKKEDEDPQDGGSLASTLSKLKRMKREEGAGATEPEYYHYIP 398
Query: 580 -GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESK-SSPRP------TAEKKKYK 631
K++ P L M +S + N + K SSP+P A + K
Sbjct: 399 PAHCKVKPNFPFLLF--MRASEQMDGDNTTHPKNAPESKKGSSPKPKSCIKAAASQGAEK 456
Query: 632 STSKSSQKSREIIETDTSSSDSD-ESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQ 690
+ S+ S++ +E T+ S S E++ + + ES+ V + + E +S
Sbjct: 457 TVSEVSEQPKETSMTEPSEPGSKAEAKKALGGDVSDQSLESHSQKVSETQMCESNSSKET 516
Query: 691 RMFSPMEEKELLSPLSEPDDRYPLIVK---------IDLNLLTRIPGKPYKETEPPKGEK 741
+ +P ++ P +P++ K +L + T+ P +
Sbjct: 517 SLATPAGKESQEGPKHPTGPFFPVLSKDESTALQWPSELLIFTKAEPSISYSCNPLYFDF 576
Query: 742 KNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTED--KNSAGHK--PSSN 797
K K R + + + + K + D ++SK+ E ++S G P+S
Sbjct: 577 KLSRNKDARTKGTEKPKDIGSSSKDHLQGLDPGEPNKSKEVGGEKIVRSSGGRMDAPASG 636
Query: 798 RESS---KQSAAKEKDLLPSPAG-PVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSG 853
S KQ G +PSK K G R + KSS + K +
Sbjct: 637 SACSGLNKQEPGGSHGSETEDTGRSLPSK--KERSGKSHRHKKKKKHKKSSKHKRKHKAD 694
Query: 854 SSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK--PRRTKLVFDD 910
+ + SS +K++ + K+ K AP+ S P P S PRR + DD
Sbjct: 695 TEEKSSKAESGEKSKKRKKRKRKKNKSSAPADSERGPKPEPPGSGSPAPPRRRRRAQDD 753
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 81.6 bits (200), Expect = 4e-15
Identities = 116/560 (20%), Positives = 219/560 (39%), Gaps = 75/560 (13%)
Query: 349 TKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPG 408
+ E ++ G +K P+K K+ K SS E SD + + D+ G
Sbjct: 90 SSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQKG 149
Query: 409 SNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPP 468
+ ++ + + + SDS+S+SSS D EP ++ P+ P
Sbjct: 150 VKPQAK--------------AAKAPPKKAKSSDSDSDSSSED----EPPKNQKPKITPV- 190
Query: 469 TNKWQLDNWLNKVNPH------KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPK 522
T K Q K P K++ + S+ SS + E+ + + PK
Sbjct: 191 TVKAQ-----TKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPK 245
Query: 523 ET--------SSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAA 574
+ ++ TP R S + + S QK P ++ P +
Sbjct: 246 KQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSAPPPKKSLG 305
Query: 575 AEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTS 634
+ P+ +E + PV+ + ++ + + P SK++ +P KK +S+S
Sbjct: 306 TQPPKKA--VEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSS 363
Query: 635 KSSQKSREIIETDTSSSDSDESESLPPSS---QTPKYPESNRTP-VKPSSVEEEDSFFRQ 690
SS D+ SS+ DE+ S P + + K + ++P VKP++ ++ Q
Sbjct: 364 DSS---------DSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 691 RMFSPMEEK---ELLSPLSEPDDRYPLIV----KIDLNLLTRIPGKPYKETEPPKGEKKN 743
++ + + E S SE + ++ K +P K + P+G + +
Sbjct: 415 KLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAK-----QAPQGSRDS 469
Query: 744 VPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQ 803
+ + ++++ EK S +K + A+ SK P + K A SSN SS
Sbjct: 470 SSDSDSSSSEEE-EEKTSKSAVKKKPQKVAGGAAPSK-PASAKKGKA---ESSNSSSSDD 524
Query: 804 SAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSS---KNSSS 860
S+ +E++ L P P + PK +G+ T + K+S +E ++ S S
Sbjct: 525 SSEEEEEKLKGKGSPRP-QAPKA-NGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGS 582
Query: 861 TSKQKKTEGKTSSSSKEVKE 880
K+K+ E + + + K+
Sbjct: 583 LKKRKQNEAAKEAETPQAKK 602
Score = 80.5 bits (197), Expect = 9e-15
Identities = 146/651 (22%), Positives = 236/651 (36%), Gaps = 105/651 (16%)
Query: 12 KERERRNQEIQ--QGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGN--YDEMKDFIG 67
++ +E+Q + A P+ + P K +K + SS +S + D+ K +
Sbjct: 88 EDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQKKQPVQ 147
Query: 68 DRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGL 127
P+ A P + + + + E +Q K TPV T K +
Sbjct: 148 KGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPP-KNQKPKITPVTVKAQTKAPPKPARAA 206
Query: 128 QSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAV 187
+ + S+ SSS ++SS S S +K + + + K
Sbjct: 207 PKIANGKAASSSSSSSSSSS-----------SDDSEEEKAAATPKKTVPKKQVVAKAPVK 255
Query: 188 SSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSN 247
++ + S D S E + K P + P P+SS PPS
Sbjct: 256 AATTPTRKSSSSEDSSSDEEEEQKKPMK-----NKPG--PYSSVP------PPSAPPPKK 302
Query: 248 SMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTK--LKIPSQPL 305
S+ +P P E +P SSE S +S +S E KP +KA ++K K P
Sbjct: 303 SLGTQP-----PKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357
Query: 306 DASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRY 365
A +S D S D + S P T K +K TK +
Sbjct: 358 AAESSSDSSDSDSSEDDEAPSKPAGTT------KNSSNKPAVTTK-------SPAVKPAA 404
Query: 366 NPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRST-PGSNSEPSHHNSEGADNS 424
P + G Q K D S E S E++ K M +T P + ++ A S
Sbjct: 405 APKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAK--------AALS 456
Query: 425 RDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPH 484
+ GS SS S+S+SSSS+ E + S+SA K P
Sbjct: 457 LPAKQAPQGSRDSS---SDSDSSSSEEEEEKTSKSAV------------------KKKPQ 495
Query: 485 KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGR 544
KV+ ++ PS K+G+ + + +S +D S +E G+
Sbjct: 496 KVAGGAA-----PSKPASAKKGKAESSNSSSSDDSSEEEEEKL--------------KGK 536
Query: 545 GRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAA 604
G + A + T T Q KA K + EE K ++ V + S+ + A
Sbjct: 537 GSPRPQAPKANGTSALTA---QNGKAAKNSEEEEEE--KKKAAVVVSKSGSLKKRKQNEA 591
Query: 605 TKGSRKPNIKKESKSSPR--PTAEKKKYKSTSKSSQKSREIIETDTSSSDS 653
K + P KK +P P +K + +++S + E IE D+ +D+
Sbjct: 592 AKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADN 642
Score = 79.7 bits (195), Expect = 1e-14
Identities = 142/644 (22%), Positives = 227/644 (35%), Gaps = 85/644 (13%)
Query: 295 LTKLKIPSQPLDASA--------SGDVSCVDEILKEMTHSWPPPLTAIHTPCKT---EPS 343
L K+P + L A+ S ++ +E PP P K P
Sbjct: 58 LKSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPG 117
Query: 344 KFPFPTKESQQSNFGTGE-----------QKRYNP-SKTSNGHQSKSMLKDDLKLSSSED 391
K ES S + + QK P +K + K+ D SSSED
Sbjct: 118 KAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSED 177
Query: 392 SDGEQDCDKTMPRSTPGSNSEPSH--HNSEGADNSRDDSSSHSGSESSSGSDSESESSSS 449
+ K P + P + N + SSS S S SSS DSE E +++
Sbjct: 178 EPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAA 237
Query: 450 DSEANEPSQ-----------------SASPEPEPPPTNKWQLDNWLNKVNPHKV------ 486
+ P + S+S E + Q NK P+
Sbjct: 238 TPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPPPSA 297
Query: 487 -SPASSVDSNIPSSQGYKKEGREQGTGNS-YTDTSGPKETSSATPGRDSKTIQKGSESGR 544
P S+ + P K++ E +S +D+S +E T SK K + +
Sbjct: 298 PPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKK 357
Query: 545 GRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAA 604
+ S SDS + +P K ++ +P K + P K
Sbjct: 358 AAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQKLL 417
Query: 605 TKGSRKPNIKKESKSSPRPTAEK----KKYKSTSKSS---------QKSREIIETDTSSS 651
T+ + + ++ES SS +K K K+T+K++ Q SR+ +D+ SS
Sbjct: 418 TRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRD-SSSDSDSS 476
Query: 652 DSDESESLPPSSQTPKYPE---SNRTPVKPSSVEE---EDSFFRQRMFSPMEEKELLSPL 705
S+E E S K P+ P KP+S ++ E S S EE+E L
Sbjct: 477 SSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGK 536
Query: 706 SEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGK 765
P + P + LT GK K +E + EKK +A S+ S K +
Sbjct: 537 GSPRPQAP--KANGTSALTAQNGKAAKNSEEEEEEKK--------KAAVVVSKSGSLKKR 586
Query: 766 RKHKNEDDNRASESKKPKTEDKNS-AGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDP 824
++++ + ++KK K + N+ K R SS +E+++ S D
Sbjct: 587 KQNEAAKEAETPQAKKIKLQTPNTFPKRKKGEKRASSPFRRVREEEIEVDSRVADNSFDA 646
Query: 825 KT----EHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQ 864
K + G R + + + KS + + S S S Q
Sbjct: 647 KRGAAGDWGERANQVLKFTKGKSFRHEKTKKKRGSYRGGSISVQ 690
Score = 75.1 bits (183), Expect = 4e-13
Identities = 103/482 (21%), Positives = 179/482 (37%), Gaps = 75/482 (15%)
Query: 488 PASSVDSNIPSSQGYKKEGREQGTGNSYTD---TSGPKETSSATPGR-----DSKTIQKG 539
P + +N P ++ KK+ + +S + GP +A P + K K
Sbjct: 64 PERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKA 123
Query: 540 SESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSS 599
SES + S D Q++ +K K KAA P+ +S++ P +
Sbjct: 124 SESSSSEESSD-DDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKN 182
Query: 600 RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESE-- 657
+ T + +K ++K+ P+P K + +S S + +SSS SD+SE
Sbjct: 183 QKPKITPVT----VKAQTKAPPKPARAAPKIANGKAASSSS-----SSSSSSSSDDSEEE 233
Query: 658 --SLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRY--- 712
+ P PK + PVK ++ S + S EE+E P+ Y
Sbjct: 234 KAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSD-EEEEQKKPMKNKPGPYSSV 292
Query: 713 --PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKN 770
P +L T+ P K ++ +P + + + E + +++ + K K
Sbjct: 293 PPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKP 352
Query: 771 EDDNRASESKKPKTE-DKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHG 829
+A+ES ++ D + PS ++K S+ K SPA P+ PK G
Sbjct: 353 PPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVK-PAAAPKQPVG 411
Query: 830 SRKRTISQ----SSSLKSSSNSNKETS--------------------------GSSKNSS 859
++ +++ SSS + SS+S +E + GS +SS
Sbjct: 412 GGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSS 471
Query: 860 STSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTL---------------DSSKPRRT 904
+ E + +S VK+K + PS P DSS+
Sbjct: 472 DSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEE 531
Query: 905 KL 906
KL
Sbjct: 532 KL 533
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 80.5 bits (197), Expect = 9e-15
Identities = 149/602 (24%), Positives = 213/602 (35%), Gaps = 85/602 (14%)
Query: 98 RHG-GSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESY 156
+HG GS QSS++ G S S+ R G GHSS GS SG +SS H S
Sbjct: 638 QHGSGSSQSSRYGQQGSGSGQSPSRGRH-GSDFGHSSSYGQHGSGSGWSSSNGPHGSVSG 696
Query: 157 NNSGSSSRK-KGQHG--SEHSKSRSSSPG-KPQAVSSLNSSHSRSHGND---------HH 203
+SG + GQ S+H S S G + S SS S HG+ H
Sbjct: 697 QSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG 756
Query: 204 SKEHQRSKSPRDPDANWDSPSRVPFSS--------GQHSTQSFPPSLMSKSNSMLQKPTA 255
S HQ S R + SPSRV S GQH + + S S + +
Sbjct: 757 SGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASG 816
Query: 256 YVR--PMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDV 313
+ + GQ + +S H+SSQ S + SS H S+SG
Sbjct: 817 FGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQH------------DSSSGQS 864
Query: 314 SCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNG 373
S + + +H H + + Q G+G+ Y + +G
Sbjct: 865 SSYGQ-HESASH---------HASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG 914
Query: 374 HQSKSMLKDDLKLSSS---EDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDS-S 429
S S SS S Q T S G +S H S +SR +
Sbjct: 915 RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHG 974
Query: 430 SHSGSESSSG--SDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDN---------WL 478
S SGS SS G +S + QS SP + Q + W
Sbjct: 975 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWS 1034
Query: 479 NKVNPHKVSPASSV-----DSNIPSSQGYKKEGREQG---TGNSYTDTSGPKET---SSA 527
+ P++ S +S S GY + G G T + TSG + A
Sbjct: 1035 SSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1094
Query: 528 TPGRDSKTIQKGS----ESGRGRQKS-PAQSDSTTQRRTVGKKQPK-------KAEKAAA 575
+ G+ S Q GS SG GRQ S QS QR + ++ P +++
Sbjct: 1095 SSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSS 1154
Query: 576 EEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSK 635
+ GL S +SS SS + GS + + S ++ +++ S+S
Sbjct: 1155 GQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSG 1214
Query: 636 SS 637
SS
Sbjct: 1215 SS 1216
Score = 77.0 bits (188), Expect = 1e-13
Identities = 179/849 (21%), Positives = 270/849 (31%), Gaps = 76/849 (8%)
Query: 91 NPNFFEQRHG-GSHQSSKWTPVGPAPSTSQSQ-------KRSSGL-----QSGHSSQRTS 137
+P+ RHG GS QSS ++P G S S+ SSGL +SG SS
Sbjct: 1476 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQ 1535
Query: 138 AGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRS 197
GSSSG +S+ +H + SG SS GQHG+ S +SSS G+ + SS +S + R
Sbjct: 1536 HGSSSGHSSTHGQHG----STSGQSS-SCGQHGA--SSGQSSSHGQHGSGSSQSSGYGRQ 1588
Query: 198 HGNDHHSKEH-QRSKSPRDPDA--NWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPT 254
S H QR R + S S SSGQH + S S + +
Sbjct: 1589 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1648
Query: 255 AYVRPMDGQE-----SMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASA 309
+Y + G S + + HG+S + + S
Sbjct: 1649 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSG 1708
Query: 310 SGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSK 369
SG + HS + S+ P+ ++ S FG E
Sbjct: 1709 SGQSPSRGRHGSGLGHSSSHGQHG--SGSGRSSSRGPYESRSGHSSVFGQHE-------- 1758
Query: 370 TSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSS 429
+ +GH S S S C + ST G +S S +S
Sbjct: 1759 SGSGHSSAY---------SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQH 1809
Query: 430 SHSGSESSSGSDSESESSSSDSEANEPSQS--ASPEPEPPPTNKWQLDNWLNKVNPHKVS 487
S+SSS S S S S S S +S + + W + + + S
Sbjct: 1810 GSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1869
Query: 488 PASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQ 547
+S+ S GY + G G +SY E + G+ S+ Q GS SG
Sbjct: 1870 GFGHHESSSWQSSGYTQHGSGSGHSSSY-------EQHGSRSGQSSRGEQHGSSSGSSSS 1922
Query: 548 KSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPR-----GGLKIESETPVDLASSMPSSRHK 602
S S R+++G Q + R G + S P S SSR
Sbjct: 1923 YGQHGSGS---RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGP 1979
Query: 603 AATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSS----------D 652
+ + S + + + S+ SS + + SSS
Sbjct: 1980 YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQS 2039
Query: 653 SDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRY 712
S + SSQ+ Y + + S RQ S
Sbjct: 2040 SSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGP 2099
Query: 713 PLIVKIDLNLLTRIPGKP--YKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKN 770
L G+ Y + G + +R Q E+ + +
Sbjct: 2100 GLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRY 2159
Query: 771 EDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGS 830
S + +GH PS R S + S +G S+ P
Sbjct: 2160 GQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSG 2219
Query: 831 RKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCP 890
Q S S++ + S + S + T G++S+ +E SSS
Sbjct: 2220 HSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQH 2279
Query: 891 PSAPTLDSS 899
S + SS
Sbjct: 2280 GSGSSQSSS 2288
Score = 75.5 bits (184), Expect = 3e-13
Identities = 145/587 (24%), Positives = 209/587 (35%), Gaps = 86/587 (14%)
Query: 85 SADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGT 144
S+ + P E G H+SS S+S SQ S SGHSS GS SG
Sbjct: 2092 SSSGQHGPGLGESSGFGHHESSS------GQSSSYSQHGSG---SGHSSGYGQHGSRSGQ 2142
Query: 145 NSSGQRHDRES-----YNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHG 199
+S G+RH S Y GS SR+ HG + S S SP + + S S HS SHG
Sbjct: 2143 SSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGS-GHSPSRGRHGS--GSGHSSSHG 2199
Query: 200 NDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNS-----MLQKPT 254
S+ P ++S S GQH + S S S+ S Q
Sbjct: 2200 QHGSGSGRSSSRGP------YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH 2253
Query: 255 AYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVS 314
E + + S HG+ ++ + + PS+ S SG S
Sbjct: 2254 GSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSS 2313
Query: 315 CVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGH 374
+ + S + H + S F S QS+ Y + +GH
Sbjct: 2314 SYGQ---HGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSS-------GYTQHGSGSGH 2363
Query: 375 QSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGS 434
S + S + S GE+ S+ GS+S H S G+ S SGS
Sbjct: 2364 SSS---YEQHGSRSGQSSRGERH------GSSSGSSSSYGQHGS-GSRQSLGHGQHGSGS 2413
Query: 435 -ESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSV- 492
+S S S S S S + P S S W + P++ S
Sbjct: 2414 GQSPSPSRGRHGSGSGQSSSYSPYGSGS--------------GWSSSRGPYESGSGHSSG 2459
Query: 493 ----DSNIPSSQGYKKEGREQG---TGNSYTDTSGPKET---SSATPGRDSKTIQKGS-- 540
+S S GY + G G T + TSG + A+ G+ S Q GS
Sbjct: 2460 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 2519
Query: 541 --ESGRGRQKS-PAQSDSTTQRRTVGKKQPK-------KAEKAAAEEPRGGLKIESETPV 590
SG GRQ S QS QR + ++ P +++ + GL S
Sbjct: 2520 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 2579
Query: 591 DLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSS 637
+SS SS + GS + + S ++ +++ S+S SS
Sbjct: 2580 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS 2626
Score = 74.7 bits (182), Expect = 5e-13
Identities = 146/589 (24%), Positives = 210/589 (35%), Gaps = 76/589 (12%)
Query: 97 QRHGGSHQSSKWTPVGPAPSTSQSQ-KRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRES 155
QR GS QS + G S S + SGL G SS SSSG +SS +H S
Sbjct: 1130 QRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGL--GESSGFGHHESSSGQSSSYSQHGSGS 1187
Query: 156 YNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRD 215
++SG GQHGS +S SS G+ +SS S SH H S Q S R
Sbjct: 1188 GHSSGY-----GQHGS---RSGQSSRGERHG----SSSGSSSHYGQHGSGSRQSSGHGRQ 1235
Query: 216 PDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHY 275
+ SPSR SG + S S + P S + +H
Sbjct: 1236 GSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYE-------SRSGHSSVFGQHE 1288
Query: 276 SSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIH 335
S H ++ ++ S H SQ S SG S D+ E + +
Sbjct: 1289 SGSGHSSAYSQ-HGSGSGHFC-----SQGQHGSTSGQSSTFDQ---EGSSTGQSSSYGHR 1339
Query: 336 TPCKTEPSKFPFPTKESQQS------NFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSS 389
++ S + S QS G+G Y + +G S S SS
Sbjct: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1399
Query: 390 ----EDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDD-SSSHSGSESSSG--SDS 442
+S Q T S G +S H S +SR + S SGS SS G
Sbjct: 1400 GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG 1459
Query: 443 ESESSSSDSEANEPSQSASPEPEPPPTNKWQLDN---------WLNKVNPHKVSPASSV- 492
+S + QS SP + Q + W + P++ + S
Sbjct: 1460 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSG 1519
Query: 493 ----DSNIPSSQGYKKEGREQG---TGNSYTDTSGPKET---SSATPGRDSKTIQKGS-- 540
+S S GY + G G T + TSG + A+ G+ S Q GS
Sbjct: 1520 LGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGS 1579
Query: 541 --ESGRGRQKS-PAQSDSTTQRRTVGKKQPK-------KAEKAAAEEPRGGLKIESETPV 590
SG GRQ S QS QR + ++ P +++ + GL S
Sbjct: 1580 SQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGH 1639
Query: 591 DLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQK 639
+SS SS + GS + + S ++ +++ S+S+SS +
Sbjct: 1640 HESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSR 1688
Score = 73.6 bits (179), Expect = 1e-12
Identities = 182/850 (21%), Positives = 280/850 (32%), Gaps = 104/850 (12%)
Query: 91 NPNFFEQRHG-GSHQSSKWTPVGPAPSTSQSQK-------RSSGL-----QSGHSSQRTS 137
+P+ RHG GS QSS + P G S S+ SSGL +SG SS
Sbjct: 1946 SPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2005
Query: 138 AGSSSGTNSSGQRHDRESYNNS-----GSSSRKKGQHGSEHS-KSRSSSPGKPQAVSSLN 191
GSSSG +S+ +H S +S G+SS + HG S S+SS G+ + S +
Sbjct: 2006 HGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 2065
Query: 192 SSHSRSHGNDHHSKEHQR--SKSPRDPDANWDSPSRVPFSS-GQHSTQSFPPSLMSKSNS 248
H + S + R S S R + P S G H + S S S+ S
Sbjct: 2066 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGS 2125
Query: 249 MLQKPTAYVR--PMDGQESMEPKLSSEHYSSQ---SHGNSMTELKPSSKAHLTKLKIPSQ 303
+ Y + GQ S + S SS HG+ + + PS+
Sbjct: 2126 GSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSR 2185
Query: 304 PLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQK 363
S SG S + S S+ P+ ++ S FG E
Sbjct: 2186 GRHGSGSGHSSSHGQHGSGSGRS---------------SSRGPYESRSGHSSVFGQHE-- 2228
Query: 364 RYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADN 423
+ +GH S S S C + ST G +S S +
Sbjct: 2229 ------SGSGHSSAY---------SQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS 2273
Query: 424 SRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQS--ASPEPEPPPTNKWQLDNWLNKV 481
S S+SSS S S S S S S +S + + W + +
Sbjct: 2274 SSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 2333
Query: 482 NPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSE 541
+ S +S+ S GY + G G +SY E + G+ S+ + GS
Sbjct: 2334 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSY-------EQHGSRSGQSSRGERHGSS 2386
Query: 542 SGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRG-----GLKIESETPVDLASSM 596
SG S S R+++G Q + RG + S +P S
Sbjct: 2387 SGSSSSYGQHGSGS---RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGW 2443
Query: 597 PSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSS----- 651
SSR + + S + + + S+ SS + + SSS
Sbjct: 2444 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 2503
Query: 652 -----DSDESESLPPSSQTPKYPE----SNRTP---VKPSSVEEEDSFFRQRMFSPMEEK 699
S + SSQ+ Y S ++P + S + S+ R S
Sbjct: 2504 ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 2563
Query: 700 --ELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQAS 757
+ S L E + + Y + G + +R Q
Sbjct: 2564 SGQHGSGLGESSG-------FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 2616
Query: 758 EKV-SNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPA 816
E+ S+ G H + + + +S + S G PS R S + S +
Sbjct: 2617 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGS-GQSPSRGRHGSGLGHSSSHGQHGSGS 2675
Query: 817 GPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSK 876
G S+ P Q S S++ + S + S + T G++S+ +
Sbjct: 2676 GRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2735
Query: 877 EVKEKAPSSS 886
E SSS
Sbjct: 2736 EGSSTGQSSS 2745
Score = 69.7 bits (169), Expect = 2e-11
Identities = 135/581 (23%), Positives = 200/581 (34%), Gaps = 57/581 (9%)
Query: 3 REDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEM 62
R+D + + ++ E +E ++ E +F SS E D S ++ L
Sbjct: 102 RDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGE-------NDSYSRNVRGSLKP---- 150
Query: 63 KDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQK 122
G SI + ++ + + + +++ SHQSS G S +
Sbjct: 151 ----GTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYG 206
Query: 123 RSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRES-----YNNSGSSSRKKGQHGSEHSKSR 177
+ G SG SS + GS SG +S +H S Y+ GS S +G S+S
Sbjct: 207 Q-HGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSG 265
Query: 178 SSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQ-HST- 235
SS G+ SS +SS HG S Q R + SPS V SG HS+
Sbjct: 266 QSSRGERHRSSSGSSSSYGQHG----SGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSS 321
Query: 236 --QSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLS--SEHYSSQSHGNSMTELKPSS 291
Q S S S + + ES + S S+H S H +S + +S
Sbjct: 322 HGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTS 381
Query: 292 KAHLTKLKIPSQPLDASASGD-VSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTK 350
+ + S +S+ G S HS + H + + P
Sbjct: 382 GQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSP---- 437
Query: 351 ESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSN 410
S Q G G P + +G+ S + SSSE S G T S G +
Sbjct: 438 SSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHE----SSSEHSSG-----YTQHGSGSGHS 488
Query: 411 SEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTN 470
S H S +SR + S SSS S S S + S S P P
Sbjct: 489 SGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQ-SPSPSRGR 547
Query: 471 KWQLDNWLNKVNPH-----KVSPASSVDSNIPSSQGYKKEGREQGTGNSY---TDTSGPK 522
+ PH + S +S S G + G + Y +SG
Sbjct: 548 HESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHS 607
Query: 523 ET---SSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRR 560
T +T G+ S Q G+ SG+ S S+ R
Sbjct: 608 STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSR 648
Score = 68.2 bits (165), Expect = 4e-11
Identities = 181/874 (20%), Positives = 278/874 (31%), Gaps = 126/874 (14%)
Query: 91 NPNFFEQRHG-GSHQSSKWTPVGPAPSTSQSQK-------RSSGL--------------- 127
+P+ RHG GS QSS + P S S+ SSGL
Sbjct: 1006 SPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 1065
Query: 128 ---QSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKS-------- 176
SGHSS GS+SG +SS +H +SG SS GQHGS S+S
Sbjct: 1066 HGSSSGHSSTHGQHGSTSGQSSSCGQHGA----SSGQSS-SHGQHGSGSSQSSGYGRQGS 1120
Query: 177 -RSSSPGKPQAVSSLNSS-----HSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSS 230
SPG Q S S H G S +H + +S SS
Sbjct: 1121 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHES------SS 1174
Query: 231 GQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPS 290
GQ S+ S S S+ Q + + G+ SS HY HG+ +
Sbjct: 1175 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG--QHGSGSRQSSGH 1232
Query: 291 SKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTK 350
+ PS+ S G S + H + S+ P+ ++
Sbjct: 1233 GRQGSGSGHSPSRGRHGSGLGHSSSHGQ------HG---------SGSGRSSSRGPYESR 1277
Query: 351 ESQQSNF-----GTGEQKRYNPSKTSNGH-QSKSMLKDDLKLSSSEDSDGEQDCDKTMPR 404
S F G+G Y+ + +GH S+ SS+ D +G +
Sbjct: 1278 SGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG 1337
Query: 405 STPGSNSEPSHHNSEGADNSRDDS-------SSHSGSESSSGSDSESESSSSDSEANEPS 457
+S+ S + GA + + S S HS S GS S SSS +
Sbjct: 1338 HRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQ 1397
Query: 458 QSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQG---TGNS 514
S E ++ WQ S + S S Y++ G G G
Sbjct: 1398 SSGFGHHE---SSSWQ------------SSGCTQHGSGSGHSSSYEQHGSRSGQSSRGER 1442
Query: 515 YTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAA 574
+ +SG +S G S+ + G G +SP+ S R G Q
Sbjct: 1443 HGSSSG-SSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG---RHGSGSGQSSSYSPYG 1498
Query: 575 AEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTS 634
+ G S P + SS S ++ + + SS + + ++
Sbjct: 1499 S----GSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1554
Query: 635 KSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPE----SNRTP---VKPSSVEEEDSF 687
+SS + + SSS SSQ+ Y S ++P + S + S+
Sbjct: 1555 QSSSCGQHGASSGQSSSHGQHGSG---SSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSY 1611
Query: 688 FRQRMFSPMEEK--ELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVP 745
R S + S L E + + Y + G
Sbjct: 1612 GRHGSGSGRSSSSGQHGSGLGESSG-------FGHHESSSGQSSSYSQHGSGSGHSSGYG 1664
Query: 746 EKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSA 805
+ +R Q E+ + + + S + +G PS R S
Sbjct: 1665 QHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGH 1724
Query: 806 AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQK 865
+ S +G S+ P Q S S++ + S + S +
Sbjct: 1725 SSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHG 1784
Query: 866 KTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSS 899
T G++S+ +E SSS S + SS
Sbjct: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 1818
Score = 66.2 bits (160), Expect = 2e-10
Identities = 114/486 (23%), Positives = 177/486 (36%), Gaps = 60/486 (12%)
Query: 95 FEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQR------TSAGSSSGTNSSG 148
+ Q GSHQSS G S S+ R G SGHSS TS SS G SG
Sbjct: 752 YGQHGSGSHQSSGHGRQGSGSGHSPSRVR-HGSSSGHSSSHGQHGSGTSCSSSCGHYESG 810
Query: 149 Q-------RHDR---ESYNNSGSSS---RKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHS 195
+H+ + Y+ GS+S +G+HGS + +SSS G+ + S +SS+
Sbjct: 811 SGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGS--TSGQSSSSGQHDSSSGQSSSYG 868
Query: 196 RSHGNDHHSKEHQR--SKSPRDP-DANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQK 252
+ HH+ R S S + P S S S G+H + S S + S +
Sbjct: 869 QHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQ 928
Query: 253 PTAY-VRPMDGQES--MEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASA 309
+ + + GQ S + S H SS S + S+ H S+
Sbjct: 929 SSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQH------------GSS 976
Query: 310 SGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSK 369
SG S + H + H + + P P++ S G+G+ Y P +
Sbjct: 977 SGSSSSYGQ------HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGS--GSGQSSSYGPYR 1028
Query: 370 TSNGHQS-----KSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS 424
+ +G S +S L E G+ S+ S++ H ++ G +S
Sbjct: 1029 SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088
Query: 425 RDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNW-LNKVNP 483
+ SG SS G S SS SP + Q ++ +
Sbjct: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1148
Query: 484 HKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSS------ATPGRDSKTIQ 537
+ S + S + S G+ G +SY+ SS + G+ S+ +
Sbjct: 1149 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
Query: 538 KGSESG 543
GS SG
Sbjct: 1209 HGSSSG 1214
Score = 65.5 bits (158), Expect = 3e-10
Identities = 107/485 (22%), Positives = 171/485 (35%), Gaps = 73/485 (15%)
Query: 99 HGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAG---SSSGTNSSGQRHDRES 155
HG S+ +P + S G SS S G S SG S +H+ S
Sbjct: 296 HGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGS 355
Query: 156 YNNSGSS--------SRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSK-- 205
+SG S S +GQHGS + ++SS G+ + S +SS+ + HS
Sbjct: 356 GQSSGYSKHGSGSGHSSSQGQHGS--TSGQASSSGQHGSSSRQSSSYGQHESASRHSSGR 413
Query: 206 -EHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQE 264
+H S S SSGQH T S S+ + Y E
Sbjct: 414 GQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFG----RSSSSGPYVSGSGYSSGFGHHE 469
Query: 265 SMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQ-PLDASASGDVSCVDEILKEM 323
S SSEH S + S + H ++ S+ S++G S +
Sbjct: 470 S-----SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQ----- 519
Query: 324 THSWPPPLTAIHTPCKTEPSKFPFPTKESQQS-----------NFGTGEQKRYNPSKTSN 372
H + H+ + + P P++ +S +G+G P ++ +
Sbjct: 520 -HGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGS 578
Query: 373 GHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHS 432
GH S L E G+ S+ S++ H ++ G +S + S
Sbjct: 579 GHSS--------GLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATS 630
Query: 433 GSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLD--------------NWL 478
G SS G + S S+++ Q S + P + D W
Sbjct: 631 GQSSSHG-----QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWS 685
Query: 479 NKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQK 538
+ PH S S G + G+G+S+ +SG ++ S + G+ S++ Q
Sbjct: 686 SSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSH--SSGYRKHGSRS-GQSSRSEQH 742
Query: 539 GSESG 543
GS SG
Sbjct: 743 GSSSG 747
Score = 63.9 bits (154), Expect = 8e-10
Identities = 112/477 (23%), Positives = 165/477 (34%), Gaps = 61/477 (12%)
Query: 101 GSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSG 160
G H+SS W G G SGHSS GS SG +S G+RH ++SG
Sbjct: 2342 GHHESSSWQSSGYT---------QHGSGSGHSSSYEQHGSRSGQSSRGERHG----SSSG 2388
Query: 161 SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANW 220
SSS GQHGS +S G Q S S S S G S SP + W
Sbjct: 2389 SSS-SYGQHGSGSRQSL----GHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGW 2443
Query: 221 DSPSRVPFSSGQ-HSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQS 279
S SR P+ SG HS S + S + + Y + G S +H S+
Sbjct: 2444 SS-SRGPYESGSGHS------SGLGHRESRSGQSSGYGQ--HGSSSGHSSTHGQHGSTSG 2494
Query: 280 HGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPP------LTA 333
+S + SS + + S +S G ++ + S P +
Sbjct: 2495 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYG---------RQGSGSGQSPGHGQRGSGS 2545
Query: 334 IHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSD 393
+P + S Q G GE + ++S+G S SS
Sbjct: 2546 RQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2605
Query: 394 GEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEA 453
++ GS+S S H + SR SS G + S S S
Sbjct: 2606 HGSRSGQSSRGERHGSSSGSSSHYGQHGSGSR--QSSGHGRQGSGSGQSPSRGRHGSGLG 2663
Query: 454 NEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGN 513
+ S +++ ++ L SSV S G+ + G+G+
Sbjct: 2664 HSSSHGQHGSGSGRSSSRGPYESRLGH---------SSVFGQHESGSGHSSAYSQHGSGS 2714
Query: 514 SYTDTSGPKETSSATPGRDSKTIQKGSESGR----GRQKSPAQSDSTTQRRTVGKKQ 566
+ + G +T G+ S Q+GS +G+ G + S + S R G Q
Sbjct: 2715 GHFCSQG---QHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQ 2768
Score = 63.5 bits (153), Expect = 1e-09
Identities = 169/837 (20%), Positives = 267/837 (31%), Gaps = 128/837 (15%)
Query: 95 FEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRE 154
F Q GS QSS ++ G S SQ + G SG +S GSSS +SS +H+
Sbjct: 348 FGQHESGSGQSSGYSKHGSGSGHSSSQGQH-GSTSGQASSSGQHGSSSRQSSSYGQHESA 406
Query: 155 SYNNSG---------------------SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSS 193
S ++SG S GQHG+ +S SS P VS S
Sbjct: 407 SRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGP----YVSG--SG 460
Query: 194 HSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKP 253
+S G+ S EH + + S GQH ++S S + S
Sbjct: 461 YSSGFGHHESSSEHSSGYTQHGSGSGHSS------GHGQHGSRSGQSSRGERQGSSAGSS 514
Query: 254 TAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDV 313
++Y GQ + S H HG+ + PS PS+ S S
Sbjct: 515 SSY-----GQHGSGSRQSLGH---SRHGSGSGQ-SPS----------PSRGRHESGSRQS 555
Query: 314 SCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFG-----TGEQKRYNPS 368
S H + ++ S+ P+ + S G +G+ Y
Sbjct: 556 SSYGP------HGYGSGRSS---------SRGPYESGSGHSSGLGHQESRSGQSSGYGQH 600
Query: 369 KTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGS-NSEPSHHNSEGADNSRDD 427
+S+GH S SS ++ GS +S+ S + +G+ + +
Sbjct: 601 GSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSP 660
Query: 428 SSSHSGSE-SSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKV 486
S GS+ S S + S S S +N P S S Q + +K +
Sbjct: 661 SRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSG----------QSSGFGHKSGSGQS 710
Query: 487 SPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGR-------DSKTIQKG 539
S S S S GY+K G G +S ++ G S++ G+ S ++G
Sbjct: 711 SGYSQHGSGSSHSSGYRKHGSRSGQ-SSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQG 769
Query: 540 SESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSS 599
S SG + S S + G + + S S
Sbjct: 770 SGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYS 829
Query: 600 RHKAAT----KGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDE 655
+H +A+ R + +S SS + + + S + S S S +
Sbjct: 830 QHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQ 889
Query: 656 S----ESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDR 711
S + S Q+P Y + SS S Q S K S
Sbjct: 890 SPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQS--SGFGHKSSSGQSSG---- 943
Query: 712 YPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNE 771
Y + G + + +R Q SE+ +
Sbjct: 944 -------------------YTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYG 984
Query: 772 DDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLP--SPAGPVPSKDPKTEHG 829
S + + +G PS +R + + P S +G S+ P
Sbjct: 985 QHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGS 1044
Query: 830 SRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSS 886
+ S S+ + SS +SS+ + T G++SS + SSS
Sbjct: 1045 GHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSS 1101
Score = 59.7 bits (143), Expect = 2e-08
Identities = 134/606 (22%), Positives = 202/606 (33%), Gaps = 53/606 (8%)
Query: 95 FEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRE 154
+ R GS QSS + G S S+ R G SGHSS GS SG +SS RH
Sbjct: 1336 YGHRGSGSSQSSGYGRHGAGSGQSPSRGRH-GSGSGHSSSYGQHGSGSGWSSSSGRHGSG 1394
Query: 155 SYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPR 214
S +SG H S S G Q S S HS S+ H S+ Q S+ R
Sbjct: 1395 SGQSSGFG---------HHESSSWQSSGCTQHGSG--SGHSSSY-EQHGSRSGQSSRGER 1442
Query: 215 DPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEH 274
++ S S SG S QS + P+ R G S + S
Sbjct: 1443 HGSSSGSSSSYGQHGSG--SRQSLGHGQHGSGSGQSPSPS---RGRHGSGSGQSS-SYSP 1496
Query: 275 YSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAI 334
Y S S +S S +H + L + +SG TH +
Sbjct: 1497 YGSGSGWSSSRGPYESGSSHSSGLG-HRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQ 1555
Query: 335 HTPCKTEPSKFPFPTKESQQ---SNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSED 391
+ C + + Q S+ +G ++ + S S GH +
Sbjct: 1556 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHG 1615
Query: 392 SDGEQDCDKTMPRSTPGSNSEPSHH-NSEGADNSRDDSSSHSGSESSSGSDSESESSSSD 450
S + S G +S HH +S G +S S SG S G SS
Sbjct: 1616 SGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSR 1675
Query: 451 SEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQG 510
E + S +S + Q + + SP+ S G+ + G
Sbjct: 1676 GERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHG---SGLGHSSSHGQHG 1732
Query: 511 TGNSYTDTSGPKETSS----------ATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRR 560
+G+ + + GP E+ S + G S Q G SG G S Q ST+ +
Sbjct: 1733 SGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHG--SGSGHFCSQGQHGSTSGQS 1790
Query: 561 TVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSS 620
+ ++ ++++ G SS SS + + + P+ + S
Sbjct: 1791 STFDQEGSSTGQSSSHGQHGS-----------GSSQSSSYGQQGSGSGQSPSRGRHGSGS 1839
Query: 621 PRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS 680
++ + + SS R + SS S S Q+ Y + SS
Sbjct: 1840 GHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESS---SWQSSGYTQHGSGSGHSSS 1896
Query: 681 VEEEDS 686
E+ S
Sbjct: 1897 YEQHGS 1902
Score = 42.4 bits (98), Expect = 0.003
Identities = 55/181 (30%), Positives = 68/181 (37%), Gaps = 33/181 (18%)
Query: 95 FEQRHGGSHQSSKWTPVGPAPSTSQSQKR-SSGLQSGHSSQRTSAGSSSGTNSS------ 147
+ Q GS QSS G S S+ R SGL GHSS GS SG +SS
Sbjct: 2629 YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL--GHSSSHGQHGSGSGRSSSRGPYES 2686
Query: 148 --------GQRHD----RESYNNSGSSSR---KKGQHGSEHSKS-----RSSSPGKPQAV 187
GQ +Y+ GS S +GQHGS +S SS G+ +
Sbjct: 2687 RLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY 2746
Query: 188 SSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSN 247
S S+S G H +S S S S S GQH + S S S+
Sbjct: 2747 GHRGSGSSQSSGYGRHGAGSGQSLS----HGRHGSGSGQSSSYGQHGSGSGQSSGYSQHG 2802
Query: 248 S 248
S
Sbjct: 2803 S 2803
Score = 40.8 bits (94), Expect = 0.008
Identities = 41/130 (31%), Positives = 51/130 (39%), Gaps = 10/130 (7%)
Query: 84 PSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSG 143
P + + F Q GS SS ++ G SQ + G SG SS GSS+G
Sbjct: 2683 PYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQH-GSTSGQSSTFDQEGSSTG 2741
Query: 144 TNSS-GQRHDRES----YNNSGSSSRKKGQHGSEHSKSRSSSP----GKPQAVSSLNSSH 194
+SS G R S Y G+ S + HG S S SS G SS S H
Sbjct: 2742 QSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQH 2801
Query: 195 SRSHGNDHHS 204
G D +S
Sbjct: 2802 GSGSGQDGYS 2811
Score = 35.4 bits (80), Expect = 0.32
Identities = 53/232 (22%), Positives = 81/232 (34%), Gaps = 29/232 (12%)
Query: 354 QSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEP 413
Q G+G+ Y + +G S + SS S + ++ S GS S
Sbjct: 194 QCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGH 253
Query: 414 S----HHNSEGADNSRDD-SSSHSGSESSSG--------------SDSESESSSSDSEAN 454
S H S +SR + S SGS SS G S S S S
Sbjct: 254 SSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHG 313
Query: 455 EPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNS 514
S +S + + + + + S +S S GY K G+G+
Sbjct: 314 SGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSK----HGSGSG 369
Query: 515 YTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQ 566
++ + G +T G+ S + Q GS S RQ S + R + G+ Q
Sbjct: 370 HSSSQG---QHGSTSGQASSSGQHGSSS---RQSSSYGQHESASRHSSGRGQ 415
Score = 32.7 bits (73), Expect = 2.1
Identities = 85/501 (16%), Positives = 153/501 (30%), Gaps = 51/501 (10%)
Query: 390 EDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSS 449
++SD Q + S G + H S +S +D+ +SS S +S S S
Sbjct: 182 QNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQS 241
Query: 450 DSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQ 509
+ S S ++ ++ H+ S SS SS G G Q
Sbjct: 242 SGYSQHGSGSGHSSGYGQHGSR---SGQSSRGERHRSSSGSS------SSYGQHGSGSRQ 292
Query: 510 GTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDS-TTQRRTVGKKQPK 568
G+ + + S G SG G S Q S ++ + G +
Sbjct: 293 SLGHGRQGSGSRQSPSHVRHG-----------SGSGHSSSHGQHGSGSSYSYSRGHYESG 341
Query: 569 KAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKK 628
+ + + G S SS + GS + + + S+ +
Sbjct: 342 SGQTSGFGQHESG-------------SGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSG 388
Query: 629 KYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPE-SNRTPVKPSSVEEEDSF 687
++ S+S+ S + S S + S Q+P + + + + PSS + F
Sbjct: 389 QHGSSSRQSSSYGQ--HESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGF 446
Query: 688 FRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEK 747
R P S + + Y + G +
Sbjct: 447 GRSSSSGPYVSGSGYSS------------GFGHHESSSEHSSGYTQHGSGSGHSSGHGQH 494
Query: 748 HTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAK 807
+R Q E+ + S + + +G PS +R + + +
Sbjct: 495 GSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQ 554
Query: 808 EKDLLPS--PAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQK 865
P +G S+ P + S S+ + SS +SS+ +
Sbjct: 555 SSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHG 614
Query: 866 KTEGKTSSSSKEVKEKAPSSS 886
T G++SS + SSS
Sbjct: 615 STSGQSSSCGQHGATSGQSSS 635
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 80.5 bits (197), Expect = 9e-15
Identities = 89/372 (23%), Positives = 154/372 (41%), Gaps = 37/372 (9%)
Query: 564 KKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRP 623
KK+ KK K+++ +S++ D SS SS ++AT+ K KK K+S +
Sbjct: 184 KKEEKKRHKSSSSSSSSSS--DSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKH 241
Query: 624 TAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVK-PSSVE 682
EKKK K + KS+ E + + E +PP PE+ K P +
Sbjct: 242 KKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPP------IPENRFLMRKSPPKAD 295
Query: 683 EEDSFFRQRMFSPMEEKELLSPLSEPD--DRYPLIVKIDLNLLTRIPGK---PYKETEPP 737
E++ R+R E+E P S+P R L+ + + R P + P +
Sbjct: 296 EKERKNRER----ERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRD 351
Query: 738 KGEKKNVPEKHTREAQKQASEKVSN-----KGKRKHKNE-DDNRAS--ESKKPKTEDKNS 789
+ + P +E Q+ +VS+ KG + NE +N+ S K+ K D +
Sbjct: 352 RFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRN 411
Query: 790 AGHKPSSNRESSK-----QSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSS 844
P+ E K +S +KE+D+ + KD K ++ +KR S+S S
Sbjct: 412 VSESPNRKNEKEKKVKDHKSNSKERDIRRN-----SEKDDKYKNKVKKRAKSKSRSKSKE 466
Query: 845 SNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRT 904
+ +KE + + +++G+ + KE KEK S + + + SK +
Sbjct: 467 KSKSKERDSKHNRNEEKRMRSRSKGRDHENVKE-KEKQSDSKGKDQERSRSKEKSKQLES 525
Query: 905 KLVFDDRNYSAD 916
K D + S +
Sbjct: 526 KSNEHDHSKSKE 537
Score = 74.7 bits (182), Expect = 5e-13
Identities = 112/550 (20%), Positives = 196/550 (35%), Gaps = 52/550 (9%)
Query: 425 RDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPH 484
+++ H S SSS S S+S+SSS +++ S S S E K + K
Sbjct: 185 KEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSRKHKKE 244
Query: 485 KVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKE--TSSATPGRDSKTIQKGSES 542
K S S S+ E + Q T P+ +P + + +K E
Sbjct: 245 KKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRER 304
Query: 543 GRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK 602
R R+ +P S + +R + R G KI+ P R
Sbjct: 305 ERERECNPPNSQPASYQRRL-------------LVTRSGRKIKGRGP----------RRY 341
Query: 603 AATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPS 662
SR + + S++ P E ++ + SS + R I + ++ E++ P
Sbjct: 342 RTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGE-RWIKGDKSELNEIKENQRSPVR 400
Query: 663 SQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNL 722
+ K + P+ E++ + + E + SE DD+Y VK
Sbjct: 401 VKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERD--IRRNSEKDDKYKNKVKKRAKS 458
Query: 723 LTRIPGKPYKETEPPKGEKKNVPEKHTREAQK-QASEKVSNKGKR---KHKNEDDNRASE 778
+R K +++ + EK R K + E V K K+ K K+++ +R+ E
Sbjct: 459 KSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKE 518
Query: 779 SKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQS 838
K N H S ++ QS ++E D+ K +H RT +S
Sbjct: 519 KSKQLESKSNEHDHSKSKEKDRRAQSRSRECDI------------TKGKHSYNSRTRERS 566
Query: 839 SSLKSSSNSNKETSGSSKN-SSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLD 897
S S T ++ S + ++ E + S+ + + P S S
Sbjct: 567 RSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSR---SKDRRR 623
Query: 898 SSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALE 957
+ R+ + ++ + D Y + K H + + EK +Y N+ E
Sbjct: 624 RRRDSRSSEREESQSRNKDKYRNQESKSSHRKE--NSESEKRMYSKSR--DHNSSNNSRE 679
Query: 958 KNAQESKSPF 967
K A +SPF
Sbjct: 680 KKADRDQSPF 689
Score = 73.9 bits (180), Expect = 8e-13
Identities = 88/420 (20%), Positives = 178/420 (42%), Gaps = 24/420 (5%)
Query: 496 IPSSQGYKKEGREQGTGNSYTDTSGPKETSS-ATPGRDSKTIQKGSESGRGRQKSPAQSD 554
IP S+ K+E + + +S + +S ++SS + DS + +E ++K + +
Sbjct: 178 IPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKN 237
Query: 555 STTQRRTVGKKQPKKAEKAAAEEPRG-GLKIESETPVDLASSMPSSRHKAATKGSRKPNI 613
S ++ KK+ KK++K+A+ E L+ + ++ V P ++ + S
Sbjct: 238 SRKHKKE--KKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKAD 295
Query: 614 KKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNR 673
+KE K+ R + ++ +S + R ++ S++ R
Sbjct: 296 EKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRR 355
Query: 674 TPVKPSSVEEEDSFFRQRMFSPME----EKELLSPLSEPDDRYPLIVK----IDLNLLTR 725
+ P +E R R+ S +K L+ + E + R P+ VK D ++
Sbjct: 356 SETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKE-NQRSPVRVKERKITDHRNVSE 414
Query: 726 IPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTE 785
P + ++ + K K N E+ R + +K NK K++ K++ +++ E K K
Sbjct: 415 SPNRKNEKEKKVKDHKSNSKERDIRR-NSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKER 473
Query: 786 DKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSS 845
D K + N E +S +K +D + D K + R R+ +S L+S S
Sbjct: 474 DS-----KHNRNEEKRMRSRSKGRD-HENVKEKEKQSDSKGKDQERSRSKEKSKQLESKS 527
Query: 846 NSNKETSGSSKNSSSTSKQKK---TEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902
N + + K+ + S+ ++ T+GK S +S+ +E++ S + + T D + R
Sbjct: 528 NEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSR-TRERSRSRDRSRRVRSRTHDRDRSR 586
Score = 65.5 bits (158), Expect = 3e-10
Identities = 114/584 (19%), Positives = 206/584 (35%), Gaps = 83/584 (14%)
Query: 361 EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEG 420
E+KR+ S +S+ S S D + SSS+ SD E ++ + H E
Sbjct: 187 EKKRHKSSSSSSSSSSDSDSSSDSQ-SSSDSSDSESATEEKSKKRKKKHRKNSRKHKKEK 245
Query: 421 ADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPE--------PPPTNKW 472
+ S+ S+ S+SE+E+ + ++ + P PE PP ++
Sbjct: 246 KKRKK--------SKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEK 297
Query: 473 QLDNWLNK----VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDT-SGPKETSSA 527
+ N + NP PAS + + G K +GR + + + S + S
Sbjct: 298 ERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFRRSE 357
Query: 528 TPGRDSKTIQ--------------KGSESG----RGRQKSPAQ--SDSTTQRRTVGKKQP 567
TP + +Q KG +S + Q+SP + T R V +
Sbjct: 358 TPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPN 417
Query: 568 KKAEKAA------AEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSP 621
+K EK + ++ SE D + R K+ ++ K K + + S
Sbjct: 418 RKNEKEKKVKDHKSNSKERDIRRNSEKD-DKYKNKVKKRAKSKSRSKSKEKSKSKERDSK 476
Query: 622 RPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSV 681
E+K+ +S SK + + E + S + + S + K ES S
Sbjct: 477 HNRNEEKRMRSRSKG-RDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKS 535
Query: 682 EEED--------------------SFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLN 721
+E+D S R+R S + + S + D +
Sbjct: 536 KEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRD-------RSRSK 588
Query: 722 LLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKH---KNEDDNRASE 778
R + Y+ + ++ P +R ++ + S +R+ +N+D R E
Sbjct: 589 EYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQE 648
Query: 779 SK---KPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTI 835
SK + + + + S + SS S K+ D SP + E S
Sbjct: 649 SKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKN 708
Query: 836 SQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVK 879
+ ++SS + S +N K KK + ++S + E K
Sbjct: 709 KEDEKIRSSVEKENQKSKGQENDHVHEKNKKFDHESSPGTDEDK 752
Score = 55.5 bits (132), Expect = 3e-07
Identities = 108/610 (17%), Positives = 204/610 (33%), Gaps = 75/610 (12%)
Query: 113 PAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSE 172
P + +K+ S SS + + SSS + SS D ES S RKK
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKK----KH 234
Query: 173 HSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDP--DANWDSPSRVPFSS 230
SR K + S S+ S S + ++ + P N + P +
Sbjct: 235 RKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKA 294
Query: 231 GQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESME--PKLSSEHYSSQSHGNSMTELK 288
+ ++ + N +P +Y R + S Y + S S +
Sbjct: 295 DEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKGRGPRRYRTPSRSRSRDRFR 354
Query: 289 PS-SKAHLTKLKIPSQPLDASA-----SGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEP 342
S + H + +Q + S+ GD S ++EI + +P + +
Sbjct: 355 RSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQ-----------RSPVRVKE 403
Query: 343 SKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTM 402
K + N ++ K H+S S +D + S +D + +
Sbjct: 404 RKI------TDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAK 457
Query: 403 PRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASP 462
+S S + + N ++ S S+ + + + SDS+ + +S S
Sbjct: 458 SKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSK 517
Query: 463 EPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPK 522
E QL+ +K N H S+ +K+ R Q T G
Sbjct: 518 EKSK------QLE---SKSNEH------------DHSKSKEKDRRAQSRSRECDITKGKH 556
Query: 523 ETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR-RTVGKKQPKKAEKAAAEEPRGG 581
+S T E R R +S T R R+ K+ + E+ R
Sbjct: 557 SYNSRT-----------RERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSR 605
Query: 582 LKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSR 641
+ E TP + S R + ++ S + + +K R K ++ + S+K
Sbjct: 606 SR-ERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSHRKENSESEKRM 664
Query: 642 EIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKEL 701
D +SS++ K + +++P +D+ + M E++++
Sbjct: 665 YSKSRDHNSSNNSRE----------KKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKI 714
Query: 702 LSPLSEPDDR 711
S + + + +
Sbjct: 715 RSSVEKENQK 724
Score = 40.0 bits (92), Expect = 0.013
Identities = 32/163 (19%), Positives = 65/163 (39%), Gaps = 6/163 (3%)
Query: 738 KGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSN 797
+ +K + K E + + ++ K K K + + +++S S + D +S+ SS+
Sbjct: 155 ENQKTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSS 214
Query: 798 RESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKN 857
S +SA +EK S+ K E RK++ +SS + N + + +
Sbjct: 215 DSSDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRP 274
Query: 858 S------SSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAP 894
+ +K+ K ++ +E+ N P S P
Sbjct: 275 EEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQP 317
Score = 34.7 bits (78), Expect = 0.54
Identities = 61/328 (18%), Positives = 104/328 (31%), Gaps = 25/328 (7%)
Query: 87 DEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNS 146
D KSN + R S + K+ ++S+ RS + S +R S + +
Sbjct: 428 DHKSNSKERDIRRN-SEKDDKYK--NKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKR 484
Query: 147 SGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSK- 205
R + N ++ G + +SRS K S HS+S D ++
Sbjct: 485 MRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQS 544
Query: 206 ----------EHQRSKSPRDPDANWDSPSRV---------PFSSGQHSTQSFPPSLMSKS 246
+H + R+ + D RV S H + +S
Sbjct: 545 RSRECDITKGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRS 604
Query: 247 NSMLQK-PTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPL 305
S ++ P R D + SSE SQS + S +H K S+
Sbjct: 605 RSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSRNKDKYRNQESKSSH-RKENSESEKR 663
Query: 306 DASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRY 365
S S D + + ++ P + I + K + + + E++
Sbjct: 664 MYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQ 723
Query: 366 NPSKTSNGHQSKSMLKDDLKLSSSEDSD 393
N H + K D + S D D
Sbjct: 724 KSKGQENDHVHEKNKKFDHESSPGTDED 751
Score = 30.8 bits (68), Expect = 7.8
Identities = 28/100 (28%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 835 ISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAP 894
I L S KE K+SSS+S +SSS + + SSS + +
Sbjct: 171 ILSCGELIPKSKVKKEEKKRHKSSSSSS--------SSSSDSDSSSDSQSSSDSSDSESA 222
Query: 895 TLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSD 934
T + SK R+ K R S H ++ K+ K A S+
Sbjct: 223 TEEKSKKRKKK----HRKNSRKHKKEKKKRKKSKKSASSE 258
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 79.7 bits (195), Expect = 1e-14
Identities = 88/378 (23%), Positives = 154/378 (40%), Gaps = 34/378 (8%)
Query: 500 QGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR 559
+G K EG + SY+D E T K + G R++S ++S S ++
Sbjct: 137 KGRKNEGVIEFV--SYSDMKRALEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRS 194
Query: 560 RTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKS 619
R+ + K ++ G K + S SR K+ ++ + KKE
Sbjct: 195 RSRSRHSRKSRSRS------GSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSR 248
Query: 620 SPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS-DESESLPPSSQTPKYPESNRTPVKP 678
SP + + S KS KS++ E ++D+ + +S PS K +R+ +
Sbjct: 249 SPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERR 308
Query: 679 SSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPK 738
E+ S R R +EK L S + +R + K + K
Sbjct: 309 VEEEKRGSVSRGRS----QEKSLRQSRSRSRSKG--------GSRSRSRSRS-KSKDKRK 355
Query: 739 GEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNR 798
G K++ E +R + SE+ +G ++ D++A SKK K ED + S
Sbjct: 356 GRKRSREESRSRSRSRSKSERSRKRGSKR-----DSKAGSSKKKKKEDTD------RSQS 404
Query: 799 ESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQS-SSLKSSSNSNKETSGSSKN 857
S +S +KE++ S + + G+ + T S+S S+ KS N E+ SK+
Sbjct: 405 RSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKS 464
Query: 858 SSSTSKQKKTEGKTSSSS 875
+S T + K+ +++S S
Sbjct: 465 ASKTRSRSKSRSRSASRS 482
Score = 61.6 bits (148), Expect = 4e-09
Identities = 69/305 (22%), Positives = 125/305 (40%), Gaps = 38/305 (12%)
Query: 363 KRYNPSKTSNGHQSKSMLKDDLKLSS-----SEDSDGEQDCDKTMPRSTPGSNSEPSHHN 417
+ ++ S++ + H KS + SS S G + K+ RS S S+
Sbjct: 189 RSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSR 248
Query: 418 SEGADNSRDDSSSHSGSESSSGSDSESES--SSSDSEANEPSQSASPEPEPPPTNKWQLD 475
S + SR S SHS +S S S ++E ++D+ S+S S + +
Sbjct: 249 SPSKEKSR--SRSHSAGKSRSKSKDQAEEKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQE 306
Query: 476 NWLNKVNPHKVSPASSVDSNIPSSQGY-------------------KKEGREQGTGNSYT 516
+ + VS S + ++ S+ K++GR++ S
Sbjct: 307 RRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES-R 365
Query: 517 DTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAE 576
S + S + R SK K S + +++ +S S + R+V K++ +++
Sbjct: 366 SRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQR 425
Query: 577 EPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKS 636
E RG ESE A + +R ++ + KPN+ ES+S + +A K + +S S+S
Sbjct: 426 EGRG----ESEN----AGTNQETRSRSRSNSKSKPNLPSESRSRSK-SASKTRSRSKSRS 476
Query: 637 SQKSR 641
SR
Sbjct: 477 RSASR 481
Score = 59.7 bits (143), Expect = 2e-08
Identities = 74/320 (23%), Positives = 116/320 (36%), Gaps = 48/320 (15%)
Query: 407 PGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSS-----SDSEANEPSQSAS 461
PGS S+ S SR S S S SGS S S S S S + S+S S
Sbjct: 177 PGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRS 236
Query: 462 PEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGP 521
K + +P K S S S K + E+ N + P
Sbjct: 237 QSRSRSKKEKSR--------SPSKEKSRSRSHSAGKSRSKSKDQAEEKIQNND--NVGKP 286
Query: 522 KETSSATPGRDSKTIQKGSES----------GRGRQKSPAQSDSTTQRRTVGKKQPKKAE 571
K S + SK+ + E RGR + + S ++ R+ G + +
Sbjct: 287 KSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRS 346
Query: 572 KAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKS------------ 619
++ +++ R G K E S SR ++ ++ SRK K++SK+
Sbjct: 347 RSKSKDKRKGRKRSRE------ESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTD 400
Query: 620 -----SPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRT 674
SP + K++ + S+SSQ+ + ++ S S S P P +R+
Sbjct: 401 RSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNSKSKPNLPSESRS 460
Query: 675 PVKPSSVEEEDSFFRQRMFS 694
K +S S R R S
Sbjct: 461 RSKSASKTRSRSKSRSRSAS 480
Score = 58.9 bits (141), Expect = 3e-08
Identities = 91/344 (26%), Positives = 136/344 (39%), Gaps = 48/344 (13%)
Query: 116 STSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSK 175
S S+S RS +S HS + S SS ++ S R S + S S SR + Q S K
Sbjct: 186 SRSRSHSRSRS-RSRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKK 244
Query: 176 SRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHST 235
+S SP K + S SRS HS RSKS + + V G+ +
Sbjct: 245 EKSRSPSKEK-------SRSRS-----HSAGKSRSKSKDQAEEKIQNNDNV----GKPKS 288
Query: 236 QSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTE-LKPSSKAH 294
+S P SKS S S E ++ E S S G S + L+ S
Sbjct: 289 RS-PSRHKSKSKSR-------------SRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRS 334
Query: 295 LTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQ 354
+K S+ S S D K S + + K+E S+ ++S+
Sbjct: 335 RSKGGSRSRSRSRSKSKDKR------KGRKRSREESRSRSRSRSKSERSRKRGSKRDSKA 388
Query: 355 SNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSE-----DSDGEQDCDKTMPRSTPGS 409
+ +++ + S++ + +S S ++ K SS+ +S+ +T RS S
Sbjct: 389 GSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSRSRSNS 448
Query: 410 NSEP-----SHHNSEGADNSRDDSSSHSGSESSSGSDSESESSS 448
S+P S S+ A +R S S S S S S S S S S S
Sbjct: 449 KSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492
Score = 54.3 bits (129), Expect = 7e-07
Identities = 79/344 (22%), Positives = 133/344 (38%), Gaps = 48/344 (13%)
Query: 498 SSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTT 557
S K R + +S++ + + S + + Q S S + + +SP++ S +
Sbjct: 198 SRHSRKSRSRSGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRS 257
Query: 558 QRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKES 617
+ + GK + K K AEE KI++ V S SRHK+ + K S
Sbjct: 258 RSHSAGKSRSK--SKDQAEE-----KIQNNDNVGKPKSRSPSRHKSKS--------KSRS 302
Query: 618 KSSPRPTAEKKKYK-STSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPV 676
+S R E+K+ S +S +KS + + S S S S K R
Sbjct: 303 RSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKR--- 359
Query: 677 KPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEP 736
S EE S R R S K S+ D + K K+ +
Sbjct: 360 ---SREESRSRSRSRSKSERSRKR----GSKRDSKAG-------------SSKKKKKEDT 399
Query: 737 PKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSS 796
+ + ++ ++E + SE +G+ + +N N+ E++ + S + PS
Sbjct: 400 DRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQ--ETRSRSRSNSKSKPNLPSE 457
Query: 797 NRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSS 840
+R SK SA+K + S + S+ P SR R+ S S S
Sbjct: 458 SRSRSK-SASKTRSRSKSRSRSA-SRSP-----SRSRSRSHSRS 494
Score = 43.5 bits (101), Expect = 0.001
Identities = 31/179 (17%), Positives = 72/179 (40%), Gaps = 8/179 (4%)
Query: 724 TRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPK 783
T + G+ + E G ++ R + ++ ++ + +H + +R+ SK
Sbjct: 163 TEVNGRKIRLVEDKPGSRR-------RRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSH 215
Query: 784 TEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKS 843
++ ++ + S +S +S ++ + P K H + K + S+S
Sbjct: 216 SKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGK-SRSKSKDQAE 274
Query: 844 SSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902
N + G K+ S + + K++ ++ S + V+E+ S S +L S+ R
Sbjct: 275 EKIQNNDNVGKPKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSR 333
Score = 42.4 bits (98), Expect = 0.003
Identities = 43/174 (24%), Positives = 69/174 (39%), Gaps = 19/174 (10%)
Query: 112 GPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESY--NNSGSSSRKKGQH 169
G + S S+S+ +S + G R + S S + S +R + ++ SS+KK +
Sbjct: 338 GGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKE 397
Query: 170 GSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFS 229
++ S+SRS S + S R H S+ R +S + N ++ SR
Sbjct: 398 DTDRSQSRS---------PSRSVSKEREHAKSESSQREGRGES-ENAGTNQETRSR---- 443
Query: 230 SGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNS 283
S P+L S+S S K + R S S S+SH S
Sbjct: 444 --SRSNSKSKPNLPSESRSR-SKSASKTRSRSKSRSRSASRSPSRSRSRSHSRS 494
Score = 33.1 bits (74), Expect = 1.6
Identities = 55/218 (25%), Positives = 82/218 (37%), Gaps = 29/218 (13%)
Query: 86 ADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTN 145
+ + S+ + GS SK + S S+ +K S + S+ SAG S +
Sbjct: 210 SSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRSKS 269
Query: 146 SSGQRHDRESYNNSGS-SSRKKGQHGSEHSKSRSSSP--------------GKPQAVSSL 190
++ +N G SR +H S+ SKSRS S G+ Q SL
Sbjct: 270 KDQAEEKIQNNDNVGKPKSRSPSRHKSK-SKSRSRSQERRVEEEKRGSVSRGRSQE-KSL 327
Query: 191 NSSHSRSH---GNDHHSKEHQRSKSPRD--PDANWDSPSRVPFSSGQHSTQSFPPSLMSK 245
S SRS G+ S+ +SK R + +S SR S ++ SK
Sbjct: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSK 387
Query: 246 SNSMLQKPTAYVRPMDGQESMEPKLS----SEHYSSQS 279
+ S +K D +S P S EH S+S
Sbjct: 388 AGSSKKKKK---EDTDRSQSRSPSRSVSKEREHAKSES 422
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 79.0 bits (193), Expect = 3e-14
Identities = 204/903 (22%), Positives = 323/903 (35%), Gaps = 139/903 (15%)
Query: 114 APSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEH 173
APS S+K S+ Q HSSQ +S S S + S D ++ ++ H
Sbjct: 453 APSCGSSEKSSAASQ--HSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVH 510
Query: 174 SK---SRSSSPGKPQAVSSLNSSHSRSHGNDHHSK--------EHQRSKSPRDPDANWDS 222
S+S S S RS G+ K + Q S SP P
Sbjct: 511 PPLPISQSPENESNDRRSRRYSVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLTPPP 570
Query: 223 PSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGN 282
P + S H+ PP++ S + A PM G+ + + ++S H
Sbjct: 571 PLQPASSISDHTPWLMPPTIPLASPFL----PASTAPMQGKRKSILREPTFRWTSLKHSR 626
Query: 283 SMTELKPSSK---AHLTKLKI-------PSQPLDA------SASGDV------SCVDEIL 320
S + S+K L + I P P D SASG S +
Sbjct: 627 SEPQYFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGT 686
Query: 321 KEMTHSWPPPLTAIH-TPCKTEPSKFPFPTKESQQSNFGTG---------EQKRYNPSKT 370
+ H P L A TP + F T S +++ GT ++K ++P ++
Sbjct: 687 RFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRS 746
Query: 371 SNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSS 430
S SM +LSSSE S T P S S S + A N S
Sbjct: 747 EPRSPSHSMRTRSGRLSSSELSP------LTPPSSVSSSLSISVSPLATSALNPTFTFPS 800
Query: 431 HSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPP-TNKWQLDNWLNKVN-PHKVSP 488
HS ++S ++ S EP S+SP P P T Q + NK P ++S
Sbjct: 801 HSLTQSGESAEKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSK 860
Query: 489 ASSVDSNIPSSQGYK------KEGREQGTGNSYTDTSGPKETSSATP-GRDSK------- 534
D ++ + + KE + + S + +S+ P GR SK
Sbjct: 861 DRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGED 920
Query: 535 -TIQKGSESGRGRQKSPAQSDSTTQRR-TVGKKQPKKAEKAAAEEPRGGLKIES------ 586
++ GR+KS + T T+G K K ++ RG L+ +
Sbjct: 921 VATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKT-KILIKKGRGNLEKTNLDLGPT 979
Query: 587 ----ETPVDLASSMPSS---RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQK 639
E L S PSS +H ++ GS K + R + KK K+ +K
Sbjct: 980 APSLEKEKTLCLSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEK 1039
Query: 640 SREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPV----KPSSVEEEDSFFRQRMFSP 695
S+ + +TD + ES+S S + P+ R + +V +D + P
Sbjct: 1040 SKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALGRKRAVFPDDMPTLSAL--P 1097
Query: 696 MEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKET-------EPP--KGEKK---- 742
EE+E + DD+ + D L P KP K EPP KG +
Sbjct: 1098 WEEREKILSSMGNDDKSSIAGSEDAEPLAP-PIKPIKPVTRNKAPQEPPVKKGRRSRRCG 1156
Query: 743 -----NVPE-----KHTREAQKQASEKVSNKGKRKHKNED----DNRASESKKPKTEDKN 788
VPE + + K + + + K ++ ++A K+ K K
Sbjct: 1157 QCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKK 1216
Query: 789 SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPS--KDPKTEHGSRKRTISQSSSLKSSSN 846
K S ++S + S K+++ S P PS +DP + S + + KS
Sbjct: 1217 EKKSKTSEKKDSKESSVV--KNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEG 1274
Query: 847 SNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKA----PSSSSNCPP--SAPTLDSSK 900
+ SK +++ + +K SSK+V + A P + PP P S+
Sbjct: 1275 NVSAPGPESKQATTPASRK--------SSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSE 1326
Query: 901 PRR 903
P++
Sbjct: 1327 PKK 1329
Score = 45.4 bits (106), Expect = 3e-04
Identities = 111/534 (20%), Positives = 190/534 (35%), Gaps = 91/534 (17%)
Query: 402 MPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSES-ESSSSDSEANEPSQSA 460
+P P P S A + ++ SG+ G+ + S SSSS S ++ S SA
Sbjct: 40 LPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSASSSSSSSSSA 99
Query: 461 SPEPEPPPTNKWQLDNWLNKVNP---HKVSPASSVDSNIPSSQ---GYKKEGREQGTGNS 514
S P L +V P + ++++ +N+ + G G G
Sbjct: 100 SSGPA------------LLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQ 147
Query: 515 YTDTSGPKETSSATPGRDSKTIQKGSESGRGRQK----------------SPAQSDSTTQ 558
+ +E +P R S +++ RGR + SP T
Sbjct: 148 FLGFGSDEEVRVRSPTR-SPSVKTSPRKPRGRPRSGSDRNSAILSDPSVFSPLNKSETKS 206
Query: 559 RRTVGKKQPKKAEKAAAEEPR-GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKES 617
+ KK K EK P G+KI+ D+ S +P KG+++ ++KK
Sbjct: 207 GDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDI-SELP--------KGNKEDSLKK-I 256
Query: 618 KSSPRPTAEK----KKYKSTSKSSQKSR---EIIETDTSSSDSDESESLPPSSQTPKYPE 670
K +P T ++ KK ++ S KS+ ++ PPS++ K P
Sbjct: 257 KRTPSATFQQATKIKKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPS 316
Query: 671 S---NRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIP 727
N KP V ++KE PL++ D +V+ +
Sbjct: 317 GLLINSELEKPQKVR--------------KDKEGTPPLTKED---KTVVRQSPRRI---- 355
Query: 728 GKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDK 787
KP + K + ++ + A+K A +K+ E + + +K KT+ K
Sbjct: 356 -KPVRIIPSSKRTDATIAKQLLQRAKKGAQKKI----------EKEAAQLQGRKVKTQVK 404
Query: 788 NSAGH-KPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSN 846
N P + SS+ + + P P K + E R + S S+
Sbjct: 405 NIRQFIMPVVSAISSRIIKTPRRFIEDEDYDP-PIKIARLESTPNSRFSAPSCGSSEKSS 463
Query: 847 SNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK 900
+ + S + SS S + T S + E + P S+ P P L S+
Sbjct: 464 AASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQ 517
Score = 42.7 bits (99), Expect = 0.002
Identities = 131/595 (22%), Positives = 214/595 (35%), Gaps = 121/595 (20%)
Query: 390 EDSDGEQDCDKTMPRSTPGSN-SEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSS 448
ED D + STP S S PS +SE + ++ SS S+SS S S S +S
Sbjct: 430 EDEDYDPPIKIARLESTPNSRFSAPSCGSSEKS-SAASQHSSQMSSDSSR-SSSPSVDTS 487
Query: 449 SDSEANEPSQ------SASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGY 502
+DS+A+E Q S +PE P P +S + +SN S+ Y
Sbjct: 488 TDSQASEEIQVLPEERSDTPEVHP----------------PLPISQSPENESNDRRSRRY 531
Query: 503 KKEGREQG---TGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR 559
R G T T S P++ +S++P T P Q S+
Sbjct: 532 SVSERSFGSRTTKKLSTLQSAPQQQTSSSPPPPLLT-----------PPPPLQPASSISD 580
Query: 560 RTVGKKQP-----KKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK----AATKGSRK 610
T P A+ +G K P +S+ SR + ++ K +++
Sbjct: 581 HTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKE 640
Query: 611 PNIKKESKSSPRP---TAEKKKYKS-TSKSSQKSREIIETDTSSSDSDESESLPPSSQTP 666
I+K + RP T E + S S S + + + S + P + P
Sbjct: 641 GLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAP 700
Query: 667 KYP--------------ESNRTPVKPSSVEEEDSFFRQRMFSPMEEK------------- 699
++ SNRT SS + ++++FSP+ +
Sbjct: 701 RFTPSEAHSRIFESVTLPSNRTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSG 760
Query: 700 ----ELLSPLSEPDD-RYPLIVKID------LNLLTRIPGKPYKETEPPKGEKKNVPEKH 748
LSPL+ P L + + LN P ++ EK P K
Sbjct: 761 RLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQS-GESAEKNQRPRKQ 819
Query: 749 TREAQKQAS-----------------EKVSNKGKRKHKNEDDNRASES-KKPKTEDKNSA 790
T + S E+ NK K + D A +S +K K+ +++
Sbjct: 820 TSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDRE 879
Query: 791 GHKPSSNRESSKQSAAKEKDLLPS----PAGPVPSKDPKTEHGSRKRTISQSSSLKSSSN 846
K + RES K+ K ++ S P G V + E ++ SSS K ++
Sbjct: 880 REK-ENKRESRKEKRKKGSEIQSSSALYPVGRVSKEKVVGE------DVATSSSAKKATG 932
Query: 847 SNKETS-GSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSK 900
K +S S + +S + T KT K+ + ++ + P+AP+L+ K
Sbjct: 933 RKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEK 987
Score = 41.2 bits (95), Expect = 0.006
Identities = 78/334 (23%), Positives = 121/334 (36%), Gaps = 55/334 (16%)
Query: 420 GADNSRDDSSSHSGSESSSGSDSESESSS-------------SDSEANEPSQSASPEPEP 466
G NS D SS S + SS SD S+SSS S+ A+ + P+ P
Sbjct: 2274 GNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVLSSKSSEGSAHNVAYPGIPKLAP 2333
Query: 467 PPTNKWQLDNWLNKVN----PHKVSPASSVDSNIPSSQ-GYKKEGREQGTGNSYTDTSGP 521
N + ++K+ P VS +S + P ++ R+Q T ++ + S P
Sbjct: 2334 QVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQRNDRDQHTDSTQSANSSP 2393
Query: 522 KETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKA--EKAAAE--- 576
E + KT++ S R + S+ RR GKK K+ EK +++
Sbjct: 2394 DEDTEV------KTLKLSGMSNRSSIINEHMGSSSRDRRQKGKKSCKETFKEKHSSKSFL 2447
Query: 577 EP-------RGGLKIESETPVDLASSMPS------SRHKAATKGSRKPNIKK------ES 617
EP G LK E V M S K KG P + K E
Sbjct: 2448 EPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDKIGDKGLSMPGVPKAPPMQVEG 2507
Query: 618 KSSPRPTAEKKKYKST------SKSSQKSREIIETDTSSSDSDESES-LPPSSQTPKYPE 670
+ K+ K T SQ + E+ +S ES S P S + +
Sbjct: 2508 SAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSPASPLQIESTSPTEPISASENPGD 2567
Query: 671 SNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSP 704
P++ +DS P++++ L+ P
Sbjct: 2568 GPVAQPSPNNTSCQDSQSNNYQNLPVQDRNLMLP 2601
Score = 38.1 bits (87), Expect = 0.049
Identities = 43/189 (22%), Positives = 70/189 (37%), Gaps = 18/189 (9%)
Query: 479 NKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQK 538
+K + K S SSV N+ S Q S + PK++SS P R K +++
Sbjct: 1220 SKTSEKKDSKESSVVKNVVDSS--------QKPTPSAREDPAPKKSSSEPPPR--KPVEE 1269
Query: 539 GSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPS 598
SE G P +TT KQ + +P E P S
Sbjct: 1270 KSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKK 1329
Query: 599 SRHKAATKGSRKPNIKKESKSSPRPT-----AEKKKYKSTSKSSQKSREIIETDTSSSDS 653
+ G P K+ K +PRP+ K+K K + Q++ + ++ S+
Sbjct: 1330 KQPPPPESG---PEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNG 1386
Query: 654 DESESLPPS 662
+ S+ P+
Sbjct: 1387 NSSKQKIPA 1395
Score = 37.4 bits (85), Expect = 0.084
Identities = 134/690 (19%), Positives = 238/690 (34%), Gaps = 69/690 (10%)
Query: 84 PSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSG 143
P E +P+ + G SS+ +P+ P S S S L S TSA + +
Sbjct: 743 PIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSS------LSISVSPLATSALNPTF 796
Query: 144 TNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHH 203
T S S SG S+ K ++ + ++S+P +P + SS
Sbjct: 797 TFPS------HSLTQSGESAEK-----NQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQT 845
Query: 204 SKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD-- 261
+ + K+P + + D+ V + + +S +K + ++
Sbjct: 846 ERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQSSSAL 905
Query: 262 ---GQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDE 318
G+ S E K+ E ++ S T K SS +H + I S L GD + V
Sbjct: 906 YPVGRVSKE-KVVGEDVATSSSAKKATGRKKSS-SHDSGTDITSVTL-----GDTTAVKT 958
Query: 319 --ILK------EMTH----SWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYN 366
++K E T+ P L T C + PS T + S+ G+ +
Sbjct: 959 KILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSS---STVKHSTSSIGSMLAQADK 1015
Query: 367 PSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRD 426
T + + K +L E S + D+ + +SE S R
Sbjct: 1016 LPMTDK-RVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRR 1074
Query: 427 DSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKV 486
+ + + D + S+ E + S + + + + P K
Sbjct: 1075 AAVALGRKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKP 1134
Query: 487 SPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGR 546
+ P +G + Q G + G P + I+K R
Sbjct: 1135 VTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQCCKMRKC 1194
Query: 547 QK---SPAQSDSTTQRRTVGKKQPKK--AEKAAAEEPRGGLKI--ESETPVDLASSMPSS 599
Q P+++ Q + V KK+ K +EK ++E + S+ P A P+
Sbjct: 1195 QNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAP 1254
Query: 600 RHKAATKGSRKP-NIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESES 658
+ ++ RKP K E + P E K+ +T+ +S+KS + + +
Sbjct: 1255 KKSSSEPPPRKPVEEKSEEGNVSAPGPESKQ--ATTPASRKSSKQVSQPALVIPPQPPTT 1312
Query: 659 LPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPM---------EEKELLSPLSEPD 709
PP + PK S +P E +Q+ +P +EKE P+++ +
Sbjct: 1313 GPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQE 1372
Query: 710 DRYPLIVKIDLNLLTRIPGKPYKETEPPKG 739
+ L + L T G K+ P G
Sbjct: 1373 NAGTLNI-----LSTLSNGNSSKQKIPADG 1397
Score = 35.4 bits (80), Expect = 0.32
Identities = 62/296 (20%), Positives = 109/296 (36%), Gaps = 22/296 (7%)
Query: 385 KLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSE-GADNSRDDSSSHSGSESSSGSDSE 443
K+S + D + D ++ +T S+ P + E G +N + D +G + E
Sbjct: 2713 KISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLKIDRPEDAG-------EKE 2765
Query: 444 SESSSSDSEANEPSQSASPEPEPPPTN-KWQLDNWLNKV-NPHKVSPASSVDSNIPSSQG 501
+ SS NEP T + L+ L+ + + +V ++ D N+ +
Sbjct: 2766 HVTKSSVGHKNEPKMDNCHSVSRVKTQGQDSLEAQLSSLESSRRVHTSTPSDKNLLDT-- 2823
Query: 502 YKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRT 561
Y E + + N+ +D G + P + K + S + +SP S S
Sbjct: 2824 YNTELLKSDSDNNNSDDCG-----NILPSDIMDFVLKNTPSMQALGESPESSSSELLNLG 2878
Query: 562 VGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKK--ESKS 619
G EK ++ + PVD + S S + P+ ++S
Sbjct: 2879 EGLGLDSNREKDMGLFEVFSQQLPTTEPVDSSVSSSISAEEQFELPLELPSDLSVLTTRS 2938
Query: 620 SPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTP 675
P+ + S S +K I E +SS+SD + P T PE + TP
Sbjct: 2939 PTVPSQNPSRLAVISDSGEKRVTITEKSVASSESDPALLSPGVDPT---PEGHMTP 2991
Score = 35.4 bits (80), Expect = 0.32
Identities = 52/241 (21%), Positives = 93/241 (38%), Gaps = 30/241 (12%)
Query: 366 NPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSR 425
+PS ++ H + + L S + ++D D NS G + ++
Sbjct: 3441 SPSGEADEHYQLQHV-NQLLASKTGIHSSQRDLDSASGPQVSNFTQTVDAPNSMGLEQNK 3499
Query: 426 DDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHK 485
SS+ S +S G S SS S + PS +P+P T ++QL HK
Sbjct: 3500 ALSSAVQASPTSPGGSPSSPSSGQRSAS--PSVPGPTKPKPK-TKRFQLPLDKGNGKKHK 3556
Query: 486 VS--PASSVDSNIPSSQGYKKEGREQGTGN-----SYTDTSGPKETSSATPGRDSKTIQK 538
VS SS +++IP + GTG DT+ +++S G+ + +
Sbjct: 3557 VSHLRTSSSEAHIPDQE---TTSLTSGTGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV 3613
Query: 539 GSESGRGRQKSPAQSDSTTQRRTVG--------------KKQPKKAEKAAAEEPRGGLKI 584
E ++PA + + +TV +++ K+ E ++P+ GL
Sbjct: 3614 LPEV--QVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKRKESITEKKPKKGLVF 3671
Query: 585 E 585
E
Sbjct: 3672 E 3672
Score = 35.0 bits (79), Expect = 0.42
Identities = 99/533 (18%), Positives = 184/533 (34%), Gaps = 75/533 (14%)
Query: 431 HSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVN--PHKVSP 488
H + + + S + SSS N + P P+ PP ++ + + ++ P +P
Sbjct: 2089 HDENRTIAHSPTSFTESSSKESQNTAEIISPPSPDRPPHSQTSGSCYYHVISKVPRIRTP 2148
Query: 489 ASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGP-------------KETSSATPGRDSKT 535
+ S P + G T + P TSS +P R
Sbjct: 2149 SYSPTQRSPGCRPLPSAGSPTPTTHEIVTVGDPLLSSGLRSIGSRRHSTSSLSPQRSKLR 2208
Query: 536 IQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASS 595
I +G ++ S STT T + K + + S T + +S
Sbjct: 2209 IMSPMRTGNTYSRNNVSSVSTTGTATDLESSAKVVDHVLG-------PLNSSTSLGQNTS 2261
Query: 596 MPSS-RHKAATKGSRKPNIKKESKSS-PRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS 653
S+ + T G++ ++ S S + +A KS+S +K++ + SS S
Sbjct: 2262 TSSNLQRTVVTVGNKNSHLDGSSSSEMKQSSASDLVSKSSSLKGEKTKVL-----SSKSS 2316
Query: 654 DESESLPPSSQTPKY-PESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSP----LSEP 708
+ S PK P+ + T + +V + SF S ++ L P +
Sbjct: 2317 EGSAHNVAYPGIPKLAPQVHNTTSRELNVSKIGSFAEPSSVSFSSKEALSFPHLHLRGQR 2376
Query: 709 DDRYPLIVKIDLNLLTRIPGKPYKETE------PPKGEKKNVPEKH----TREAQKQASE 758
+DR + P ++TE + ++ +H +R+ +++ +
Sbjct: 2377 NDR-----DQHTDSTQSANSSPDEDTEVKTLKLSGMSNRSSIINEHMGSSSRDRRQKGKK 2431
Query: 759 KVSNKGKRKHKNEDDNRASE-------SKKPKTEDK----NSAGHKPSSNRESSKQSAAK 807
K KH ++ + + KP+ D+ G +P +N S K
Sbjct: 2432 SCKETFKEKHSSKSFLEPGQVTTGEEGNLKPEFMDEVLTPEYMGQRPCNNVSSDK---IG 2488
Query: 808 EKDL-LPSPAGPVPSKDPKTEHGS-------RKRTISQSSSLKSSSNSNKETSGSSKNSS 859
+K L +P VP P GS RKRT+ + + N ++ + ++S
Sbjct: 2489 DKGLSMPG----VPKAPPMQVEGSAKELQAPRKRTVKVTLTPLKMENESQSKNALKESSP 2544
Query: 860 STSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRN 912
++ Q ++ T S + P + DS L DRN
Sbjct: 2545 ASPLQIESTSPTEPISASENPGDGPVAQPSPNNTSCQDSQSNNYQNLPVQDRN 2597
Score = 33.1 bits (74), Expect = 1.6
Identities = 35/172 (20%), Positives = 66/172 (38%), Gaps = 23/172 (13%)
Query: 533 SKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPK-KAEKAAAEEPRGGLKIESETPVD 591
S +Q S G SP+ + G +PK K ++ +G K + +
Sbjct: 3502 SSAVQASPTSPGGSPSSPSSGQRSASPSVPGPTKPKPKTKRFQLPLDKGNGKKHKVSHLR 3561
Query: 592 LASS---MPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDT 648
+SS +P + T G+ P + AE++ S +SSQK
Sbjct: 3562 TSSSEAHIPDQETTSLTSGTGTPGAE----------AEQQDTASVEQSSQKE-------- 3603
Query: 649 SSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKE 700
++ P Q + P + + +P +VEEE+S F + +++++
Sbjct: 3604 -CGQPAGQVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQ 3654
Score = 30.8 bits (68), Expect = 7.8
Identities = 103/543 (18%), Positives = 178/543 (32%), Gaps = 93/543 (17%)
Query: 12 KERERRNQEIQQ----------------GEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSM 55
KE+ ++ EIQ GED SS A K +S D +
Sbjct: 890 KEKRKKGSEIQSSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVT 949
Query: 56 LGNYDEMKDFI----GDRSIPKLVAIPKPTVPPSADEK----SNPNFFEQRHGGSHQSSK 107
LG+ +K I G ++ K PT P EK S P+ +H S S
Sbjct: 950 LGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLCLSTPSSSTVKHSTSSIGSM 1009
Query: 108 WTPVGPAPSTSQS---------------QKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHD 152
P T + +K S Q+ + SS T+ G R
Sbjct: 1010 LAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIK 1069
Query: 153 RESYNNSGSSSRKKGQHGSEHSKSRSSSPG--KPQAVSSLNSSHSRSHGNDHHSKEHQRS 210
+ + RK+ + + S+ P + + +SS+ + S ++
Sbjct: 1070 HVCRRAAVALGRKRAVFPDD-MPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPP 1128
Query: 211 KSPRDPDANWDSPSRVPFSSGQHSTQSFP------PSLMSKSNSMLQKPTAYVRPMDGQ- 263
P P +P P G+ S + P + L KP R + Q
Sbjct: 1129 IKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNIKKQC 1188
Query: 264 ------ESMEPKLSSEHYSSQSHGNSMTELKP--SSKAHLTKLKIPSQPLDASASGDVSC 315
++++ S + Q+ E K S K + + +D+S S
Sbjct: 1189 CKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSA 1248
Query: 316 VDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQ 375
++ + + S PPP + K+E P ES+Q+ + ++
Sbjct: 1249 REDPAPKKSSSEPPPRKPVEE--KSEEGNVSAPGPESKQA------------TTPASRKS 1294
Query: 376 SKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSE 435
SK + + L + + G K +P++TP SEP +
Sbjct: 1295 SKQVSQPALVIPPQPPTTGPPR--KEVPKTTP---SEPKKKQPPPPE------------- 1336
Query: 436 SSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSN 495
SG + + + + Q + +PPP NK + LN ++ +S +S
Sbjct: 1337 --SGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNILS--TLSNGNSSKQK 1392
Query: 496 IPS 498
IP+
Sbjct: 1393 IPA 1395
Score = 30.8 bits (68), Expect = 7.8
Identities = 50/242 (20%), Positives = 85/242 (35%), Gaps = 36/242 (14%)
Query: 612 NIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPES 671
NIKK+ + + ++ + QK + ++ S + E + SS +S
Sbjct: 1183 NIKKQCCKMRK--CQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDS 1240
Query: 672 NRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPY 731
++ P PS+ E+ P +K SEP R P+ K + ++ PG
Sbjct: 1241 SQKPT-PSARED-----------PAPKKSS----SEPPPRKPVEEKSEEGNVSA-PGPES 1283
Query: 732 KETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKT---EDKN 788
K+ P A +++S++VS + PKT E K
Sbjct: 1284 KQATTP--------------ASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKK 1329
Query: 789 SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSN 848
P S E SKQ + +P P + P + S S+ NS+
Sbjct: 1330 KQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSS 1389
Query: 849 KE 850
K+
Sbjct: 1390 KQ 1391
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 79.0 bits (193), Expect = 3e-14
Identities = 188/884 (21%), Positives = 304/884 (34%), Gaps = 116/884 (13%)
Query: 102 SHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSG- 160
S SSK T P +TS + S+ SS T+ S+S T + G+ + + ++S
Sbjct: 1834 SWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASST-TLGRSEESTTVHSSPV 1892
Query: 161 ------SSSRKKGQHGSEHSKSRSSSPGKPQAV----SSLNSSHSRSHGNDHHSKEHQRS 210
S +R E S + SSPG Q + SS S S H S H S
Sbjct: 1893 ATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTIS 1952
Query: 211 KSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD--------- 261
P A + P+ S G +T FP S S ++ ++ TA D
Sbjct: 1953 SPPSTTSALVEEPTSYHSSPGSTATTHFPDS--STTSGRSEESTASHSSQDATGTIVLPA 2010
Query: 262 --------GQESMEPKLSSEHYSSQSHGNSMTE-LKPSSKAHLTKLKIPSQPLDASASGD 312
G+ + P S ++ G++ T L S + + P+ L +++
Sbjct: 2011 RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTS 2070
Query: 313 VSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKES--QQSNFGTGEQKRYNPSKT 370
+E +HS P + HT + + P ++ S S+ G+ + S T
Sbjct: 2071 SGVSEE--STTSHSRP---GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 2125
Query: 371 SNGHQSKSML------KDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE---PSHHNSEGA 421
++G +S D LS + + T S+PGS P S G
Sbjct: 2126 TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 2185
Query: 422 DNSRDDSSSHSGSESSSGSDSESESSSSDSEA---NEPSQSASPEPEPPPTNKWQLDNWL 478
+ S +GS ++ S + S S E+ S P PP T ++
Sbjct: 2186 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE--- 2242
Query: 479 NKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSG--PKETSSATPGRDSKTI 536
+ + SP S+ ++ P+S + +S D SG P S T GR T
Sbjct: 2243 -ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT 2301
Query: 537 QKGSESGRGRQKSPAQSDSTT---QRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLA 593
+ SP ++ TT T G + ++ P L S T + +
Sbjct: 2302 SR---------ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 2352
Query: 594 SSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS 653
+SR + GS + S ++P + E S+S S ++ T T+S
Sbjct: 2353 EESTTSR---SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRG 2409
Query: 654 DES---ESLPPSSQTPKYPESNRT----------PVKPSSVE-------------EEDSF 687
+E S P S+ T + E + T P P+S + EE +
Sbjct: 2410 EEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTT 2469
Query: 688 FRQRMFSPMEEKELLSPLSEP-----DDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKK 742
F S LSP + P + T +PG P T P EK
Sbjct: 2470 FPS---SSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP---TTPSLSEKS 2523
Query: 743 NVPEKHTREAQKQAS-EKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESS 801
R S ++ G + + ++ + D + + S
Sbjct: 2524 TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSH 2583
Query: 802 KQSAAKEKDLLP-SPAGPVPSKDPKTEH---GSRKRTISQSSSLKSSSNSNKETSGSSKN 857
+ + LLP S PS++ T H GS +S S+ S T SS
Sbjct: 2584 SSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPG 2643
Query: 858 SSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKP 901
S+ T+ + TSS E + SS+ + + S+ P
Sbjct: 2644 STHTT--LFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSP 2685
Score = 73.6 bits (179), Expect = 1e-12
Identities = 173/827 (20%), Positives = 289/827 (34%), Gaps = 106/827 (12%)
Query: 102 SHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSG- 160
S +SK T P +TS + S+ SS T+ S+S T + G+ + + ++S
Sbjct: 3391 SWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASST-TLGRSEESTTVHSSPV 3449
Query: 161 ------SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGND----HHSKEHQRS 210
S +R E S + SSPG Q + S + G + H S H S
Sbjct: 3450 ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTIS 3509
Query: 211 KSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD--------- 261
+P A + P+ S G +T FP S S ++ ++ TA D
Sbjct: 3510 SAPSTTSALVEEPTSYHSSPGSTATTHFPDS--STTSGRSEESTASHSSQDATGTIVLPA 3567
Query: 262 --------GQESMEPKLSSEHYSSQSHGNSMTE-LKPSSKAHLTKLKIPSQPLDASASGD 312
G+ + P S ++ G++ T L S + + P+ L +++
Sbjct: 3568 RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTS 3627
Query: 313 VSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKES--QQSNFGTGEQKRYNPSKT 370
+E +HS P + HT + + P ++ S S+ G+ + S T
Sbjct: 3628 SGVSEE--STTSHSRP---GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 3682
Query: 371 SNGHQSKSML------KDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE---PSHHNSEGA 421
++G +S D LS + + T S+PGS P S G
Sbjct: 3683 TSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 3742
Query: 422 DNSRDDSSSHSGSESSSGSDSESESSSSDSEA---NEPSQSASPEPEPPPTNKWQLDNWL 478
+ S +GS ++ S + S S E+ S P PP T ++
Sbjct: 3743 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE--- 3799
Query: 479 NKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSG--PKETSSATPGRDSKTI 536
+ + SP S+ ++ P+S + +S D SG P S T GR T
Sbjct: 3800 -ESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTT 3858
Query: 537 QKGSESGRGRQKSPAQSDSTT---QRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLA 593
+ SP ++ TT T G + ++ P L S T + +
Sbjct: 3859 SR---------ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 3909
Query: 594 SSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS 653
+SR + GS + S ++P + E S+S S ++ + T+S
Sbjct: 3910 EESTTSR---SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRR 3966
Query: 654 DES---ESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDD 710
+E S P S+ T + E + T S + EE + F SP S
Sbjct: 3967 EEPTTFHSRPASTHTTLFTEDSTT----SGLTEESTAFPG------------SPASTQTG 4010
Query: 711 RYPLIVKIDL-NLLTRIP---GKPYKETEPPKGEKKN-VPEKHTREAQKQASEKVSNKGK 765
+ DL T P G + P + V E ++E + G
Sbjct: 4011 LPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS 4070
Query: 766 RKHKNEDDNRASESKKPKTED-------KNSAGHKPSSNRESSKQSAAKEKDLLPSPAGP 818
+ + + P++ D S+G S+ S+ + S
Sbjct: 4071 PTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTS 4130
Query: 819 VPSKDPKTEH---GSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTS 862
S++P T H GS + T+S S+ SS T SS + T+
Sbjct: 4131 GLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 4177
Score = 73.2 bits (178), Expect = 1e-12
Identities = 178/825 (21%), Positives = 287/825 (34%), Gaps = 104/825 (12%)
Query: 102 SHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTN-----SSGQRHDRESY 156
S S T + PA ST++ Q S+ S SS+ T + T+ S+ S
Sbjct: 753 SSTRSPHTTLSPAGSTTR-QGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSI 811
Query: 157 NNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGND----HHSKEHQRSKS 212
+ S+R E S + SSPG Q + S + G + H S H S +
Sbjct: 812 PTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSA 871
Query: 213 PRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD----------- 261
P A + P+ S G +T FP S S ++ ++ TA D
Sbjct: 872 PSTTSALVEEPTSYHSSPGSTATTHFPDS--STTSGRSEESTASHSSQDATGTIVLPARS 929
Query: 262 ------GQESMEPKLSSEHYSSQSHGNSMTE-LKPSSKAHLTKLKIPSQPLDASASGDVS 314
G+ + P S ++ G++ T L S + + P+ L + AS S
Sbjct: 930 TTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTL-SPASTTSS 988
Query: 315 CVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKES--QQSNFGTGEQKRYNPSKTSN 372
V E E T S P + HT + + P ++ S S+ G+ + S T++
Sbjct: 989 GVSE---ESTTSRSRP-GSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 1044
Query: 373 GHQSKSML------KDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE---PSHHNSEGADN 423
G +S D LS + + T S PGS P S G
Sbjct: 1045 GPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVE 1104
Query: 424 SRDDSSSHSGSESSSGSDSESESSSSDSEA---NEPSQSASPEPEPPPTNKWQLDNWLNK 480
+ S +GS ++ S + S S E+ S P PP T ++ +
Sbjct: 1105 ASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE----E 1160
Query: 481 VNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSG--PKETSSATPGRDSKTIQK 538
+ SP S+ ++ P+S + +S D SG P S T GR T +
Sbjct: 1161 STTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 1220
Query: 539 GSESGRGRQKSPAQSDSTT---QRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASS 595
SP ++ TT T G + ++ P L S T + +
Sbjct: 1221 ---------ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 1271
Query: 596 MPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDE 655
+SR + GS + S ++P + E S+S+ S ++ + T+S +E
Sbjct: 1272 STTSR---SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEE 1328
Query: 656 S---ESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRY 712
S P S+ T + E + T S + EE + F SP S
Sbjct: 1329 PTTFHSRPASTHTTLFTEDSTT----SGLTEESTAFPG------------SPASTQTGLP 1372
Query: 713 PLIVKIDL-NLLTRIP---GKPYKETEPPKGEKKN-VPEKHTREAQKQASEKVSNKGKRK 767
+ DL T P G + P + V E ++E + G
Sbjct: 1373 ATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPT 1432
Query: 768 HKNEDDNRASESKKPKTED-------KNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVP 820
+ + + P++ D S+G S+ S+ + S
Sbjct: 1433 TPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDL 1492
Query: 821 SKDPKTEH---GSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTS 862
S++P T H GS + T+S S+ SS T SS + T+
Sbjct: 1493 SQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 1537
Score = 70.5 bits (171), Expect = 9e-12
Identities = 195/876 (22%), Positives = 306/876 (34%), Gaps = 129/876 (14%)
Query: 77 IPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS-QKRSSGLQSGHSSQR 135
+P T+ E S P S S T + PA STS Q+ S+ QS SS
Sbjct: 3096 LPDDTITSGLVEASTPTH-------SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD 3148
Query: 136 TSAGSSSGTNS-----SGQRHDRESYNNSGSSSRKKGQHG-SEHSKSRSSSPGKP-QAVS 188
T+ S GT + S H R S + S G SE S + SSPG A+
Sbjct: 3149 TTP-SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALF 3207
Query: 189 SLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPS-----LM 243
S+ S G P+ P SSG T + P S L
Sbjct: 3208 PTRSATSVLVGE----------------------PTTSPISSGSTETTALPGSTTTAGLS 3245
Query: 244 SKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSH-GNSMTELKPSSKAHLTKLKIPS 302
KS + P + + + +S E +S S G++ T P S T + S
Sbjct: 3246 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGS----TTMPGVS 3301
Query: 303 QPLDASASGDVSCVDEILKEMT--HSWPPPLTAIHT-PCKTEPSKFPFPTKESQQSNFGT 359
Q AS S S + T S P T H+ P TE + P T S G
Sbjct: 3302 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTAS-----GL 3356
Query: 360 GEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNS- 418
E S T + H + L + S GE ++ P S + + P+ ++
Sbjct: 3357 LEASTPVHSSTGSPHTT-------LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAF 3409
Query: 419 -EGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSAS-PEPEPPPTNKWQLDN 476
E + S SS + S+ S + S S + + P +A+ P P T+
Sbjct: 3410 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS-----G 3464
Query: 477 WLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTI 536
+ + + SP S+ + P S G E T +S T T S+ P S +
Sbjct: 3465 LVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTT-----HTISSAPSTTSALV 3519
Query: 537 QKGSE--SGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI--ESETPVDL 592
++ + S G + DS+T T G+ + A ++ ++ G + + S T V L
Sbjct: 3520 EEPTSYHSSPGSTATTHFPDSST---TSGRSEESTASHSS-QDATGTIVLPARSTTSVLL 3575
Query: 593 ASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTS--S 650
S S + GS + S ++P + + + S+ +S + T +S S
Sbjct: 3576 GESTTSP----ISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVS 3631
Query: 651 SDSDESESLPPSSQTPKYPESNRTP-------------------VKPSSVEEEDSFFRQR 691
+S S S P S+ T +P+S TP + P+S S Q
Sbjct: 3632 EESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGS--SQE 3689
Query: 692 MFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTRE 751
+ P L + PG + P + E TR
Sbjct: 3690 STTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV 3749
Query: 752 AQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSA--GHKPSSNRESSKQSAAKEK 809
S + + + S P + +++A H S++ S S A
Sbjct: 3750 HSSTGSPRTTLS------------PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP 3797
Query: 810 DLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSG---SSKNSSSTSKQKK 866
+ P P T H T S S + +S+ + SG SS +S+++ + +
Sbjct: 3798 VEESTTYHRSPGSTPTT-HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGES 3856
Query: 867 TEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902
T + S S E+ S+++ A T S PR
Sbjct: 3857 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 3892
Score = 68.2 bits (165), Expect = 4e-11
Identities = 194/872 (22%), Positives = 301/872 (34%), Gaps = 121/872 (13%)
Query: 77 IPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS-QKRSSGLQSGHSSQR 135
+P T+ E S P S S T + PA STS Q+ S+ QS SS
Sbjct: 1539 LPDDTITSGLVEASTPTH-------SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSD 1591
Query: 136 TSAGSSSGTNS-----SGQRHDRESYNNSGSSSRKKGQHG-SEHSKSRSSSPGKP-QAVS 188
T+ S GT + S H R S + S G SE S + SSPG A+
Sbjct: 1592 TTP-SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALF 1650
Query: 189 SLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPS-----LM 243
S+ S G P+ P SSG T + P S L
Sbjct: 1651 PTRSATSVLVGE----------------------PTTSPISSGSTETTALPGSTTTAGLS 1688
Query: 244 SKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSH-GNSMTELKPSSKAHLTKLKIPS 302
KS + P + + + +S E +S S G++ T P S T + S
Sbjct: 1689 EKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPGS----TTMPGVS 1744
Query: 303 QPLDASASGDVSCVDEILKEMT--HSWPPPLTAIHT-PCKTEPSKFPFPTKESQQSNFGT 359
Q AS S S + T S P T H+ P TE + P T S G
Sbjct: 1745 QESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTAS-----GL 1799
Query: 360 GEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSE 419
E S T + H + S + S TMP +++ +
Sbjct: 1800 LEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTS 1859
Query: 420 GADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLN 479
S ++ S S ++ G ES + S A + +P P T+ +
Sbjct: 1860 HGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT----ATTPSPARSTTS-----GLVE 1910
Query: 480 KVNPHKVSPASSVDSNIPSSQ---GYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTI 536
+ + SP S+ + P S G +E R + ++T +S P TS+ S
Sbjct: 1911 ESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHS 1970
Query: 537 QKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI--ESETPVDLAS 594
GS + + DS+T T G+ + A ++ ++ G + + S T V L
Sbjct: 1971 SPGSTA------TTHFPDSST---TSGRSEESTASHSS-QDATGTIVLPARSTTSVLLGE 2020
Query: 595 SMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTS--SSD 652
S S + GS + S ++P + + + S+ +S + T +S S +
Sbjct: 2021 STTSP----ISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEE 2076
Query: 653 SDESESLPPSSQTPKYPESNRTP----------VKPSSVEEEDSFFRQRMFSPMEEKELL 702
S S S P S+ T +P+S TP P S + P +E
Sbjct: 2077 STTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTS 2136
Query: 703 --SPLS-----EPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQ 755
SP S P L + PG + P + E TR
Sbjct: 2137 HSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSST 2196
Query: 756 ASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSA--GHKPSSNRESSKQSAAKEKDLLP 813
S + + + S P + +++A H S++ S S A
Sbjct: 2197 GSPRTTLS------------PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES 2244
Query: 814 SPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSG---SSKNSSSTSKQKKTEGK 870
+ P P T H T S S + +S+ + SG SS +S+++ + + T +
Sbjct: 2245 TTYHRSPGSTPTT-HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSR 2303
Query: 871 TSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902
S S E+ S+++ A T S PR
Sbjct: 2304 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 2335
Score = 68.2 bits (165), Expect = 4e-11
Identities = 195/864 (22%), Positives = 296/864 (34%), Gaps = 126/864 (14%)
Query: 76 AIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS-QKRSSGLQSGHSSQ 134
A+P T P EKS R S T + PA +TS + S+ S S
Sbjct: 2035 ALPGSTTTPGLSEKSTTFHSSPR-------SPATTLSPASTTSSGVSEESTTSHSRPGST 2087
Query: 135 RTSAGSSSGTNSSGQRHDRESYNNSGSS------SRKKGQHGSEHSKSRSSSPGKPQAVS 188
T+A S T RH S+++ GS+ + S+ S + SSPG
Sbjct: 2088 HTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTAL 2147
Query: 189 SLNSSHSRSHGNDH---HSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSK 245
S S+ + S G + HS + + PD+ S V S+ HS+ P + +S
Sbjct: 2148 SPGSTTALSFGQESTTFHSSPGS-THTTLFPDSTTSS-GIVEASTRVHSSTGSPRTTLSP 2205
Query: 246 SNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPL 305
++S P L E + Q+H P+S H T PS P
Sbjct: 2206 ASST-----------------SPGLQGESTAFQTH--------PAS-THTT----PSPPS 2235
Query: 306 DASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRY 365
A+A + S H P H P + S + S +G
Sbjct: 2236 TATAPVEESTT-------YHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 2288
Query: 366 NPSKTSN-GHQSKSMLK----DDLKLSSSEDSDGEQDCDKTM---PRSTPGSNSEPSHHN 417
S TS G + S + + L S + G + T PRS P + P+
Sbjct: 2289 AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRS-PTTTLSPASMT 2347
Query: 418 SEGADNSRDDSSSHSGSESSSGSDSE------SESSSSDSEANEPSQSASPEPEPPPTNK 471
S G S S GS S+ S + SE S++ ++ S + P P T+
Sbjct: 2348 SLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSV 2407
Query: 472 WQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGR 531
+ P S +++ + ++ G +E + T T P ++A G
Sbjct: 2408 RGEEPTTFHSRP--ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGE 2465
Query: 532 DSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVD 591
+S T S S G SPA+S T VG+ P + ++ E T +
Sbjct: 2466 ESTTFPSSSGS-TGTTLSPARS---TTSGLVGESTPSRLSPSSTET----------TTLP 2511
Query: 592 LASSMPSSRHKAAT--KGSRKPNIKKESKSSPRPTAEK--KKYKSTSKSSQKSR------ 641
+ + PS K+ T R P ++ SP T + STS S S
Sbjct: 2512 GSPTTPSLSEKSTTFYTSPRSP----DATLSPATTTSSGVSEESSTSHSQPGSTHTTAFP 2567
Query: 642 EIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKEL 701
+ T S S S S P S+ T P S T S +E + SP
Sbjct: 2568 DSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTT----SGPSQESTTSHS---SPGSTDTA 2620
Query: 702 LSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVS 761
LSP S L + PG + P + E TR S + +
Sbjct: 2621 LSPGSTT----ALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 2676
Query: 762 NKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPS 821
+S S + E H S++ S S A + P
Sbjct: 2677 LSPA----------SSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPG 2726
Query: 822 KDPKTEHGSRKRTISQSSSLKSSSNSNKETSG---SSKNSSSTSKQKKTEGKTSSSSKEV 878
P T H T S S + +S+ + SG SS +S+++ + + T + S S E+
Sbjct: 2727 STPTT-HFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEI 2785
Query: 879 KEKAPSSSSNCPPSAPTLDSSKPR 902
S+++ A T S PR
Sbjct: 2786 TTLPGSTTTPGLSEASTTFYSSPR 2809
Score = 63.2 bits (152), Expect = 1e-09
Identities = 165/779 (21%), Positives = 261/779 (33%), Gaps = 107/779 (13%)
Query: 144 TNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHH 203
T S+ +H +S NSG S H S PG ++L SHS +
Sbjct: 203 TGSTATKHFLDSSTNSGHSEESTVSH---------SGPGATG--TTLFPSHSAT------ 245
Query: 204 SKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQ 263
P P +S T + P S + S + T Y P
Sbjct: 246 -------------SVFVGEPKTSPITSASMETTALPGSTTTAGLSE-KSTTFYSSPRSPD 291
Query: 264 ESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEM 323
++ P ++ S S ++ + +P P A D + + + +E
Sbjct: 292 RTLSPARTTS--SGVSEKSTTSHSRPG-------------PTHTIAFPDSTTMPGVSQES 336
Query: 324 T--HSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNG-------- 373
T HS P +P T PS P + S+ G + R + T++G
Sbjct: 337 TASHSIPGSTDTTLSPGTTTPSSLG-PESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPV 395
Query: 374 HQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSG 433
H S L SSS +GE ++ P S+ ++ PS S S SS S
Sbjct: 396 HSSTGSPHTTLSPSSSTTHEGEPTTFQSWP-SSKDTSPAPSGTTSAFVKLSTTYHSSPSS 454
Query: 434 SESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVD 493
+ ++ S S + S+ S + PPP + H+ SP S+
Sbjct: 455 TPTTHFSASSTTLGHSEESTPVHSSPVATATTPPPARSATSGHVEESTAYHR-SPGSTQT 513
Query: 494 SNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQS 553
+ P S E T + T T S+TP + S G ++
Sbjct: 514 MHFPESSTTSGHSEESATFHGSTT-----HTKSSTPSTTAALAHTSYHSSLGSTETTHFR 568
Query: 554 DSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETP-VDLASSMPSSRHKAATKGSRKPN 612
DS+T G+ + KA ++ + + TP V + S PS + GS +
Sbjct: 569 DSST---ISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSP----ISSGSMETT 621
Query: 613 IKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDES---ESLPPSSQTPKYP 669
S + P +EK +S S + + + TSS S+ES S P S+ T +P
Sbjct: 622 ALPGSTTKPG-LSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFP 680
Query: 670 ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGK 729
S P + +E + SP LSP S P
Sbjct: 681 GSTTMP----GLSQESTASHS---SPGPTDTTLSPGSTTASSLG-------------PEY 720
Query: 730 PYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNS 789
+ P E +P+ T +AS V + + H ++ + T +
Sbjct: 721 TTFHSRPGSTETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSW 780
Query: 790 AGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK 849
K + + SA E + PS P T +R T S L S +
Sbjct: 781 PSSKDTRPAPPTTTSAFVEPSTTSHGS---PSSIPTTHISARSTT----SGLVEESTTYH 833
Query: 850 ETSGSSKN----SSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRT 904
+ GS++ S T+ + E TS SS + S+++ PT S P T
Sbjct: 834 SSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST 892
Score = 61.2 bits (147), Expect = 5e-09
Identities = 170/712 (23%), Positives = 246/712 (34%), Gaps = 135/712 (18%)
Query: 77 IPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS-QKRSSGLQSGHSSQR 135
+P T+ E S P S S T + PA STS Q+ S+ QS SS
Sbjct: 4179 LPDDTITSGLVEASTPTH-------SSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSD 4231
Query: 136 TSAGSSSGT----NSSGQRHDRESYNNSGSSSRKKGQHG-SEHSKSRSSSPGKP-QAVSS 189
T+ S T S H R S + S G SE S + SSPG A+
Sbjct: 4232 TTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFP 4291
Query: 190 LNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPS-----LMS 244
S+ S G P+ P SSG T + P S L
Sbjct: 4292 TRSATSVLVGE----------------------PTTSPISSGSTETTALPGSTTTAGLSE 4329
Query: 245 KSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSM-TELKPSSKAHLTKLKIPSQ 303
KS + P + + + +S E +S S SM T PSS T + SQ
Sbjct: 4330 KSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSS----TTMPGVSQ 4385
Query: 304 PLDASASGDVSCVDEILKEMT--HSWPPPLTAIHT-PCKTEPSKFPFPTKESQQSNFGTG 360
AS S S + T S P T H+ P TE + P T S G
Sbjct: 4386 ESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTAS-----GLL 4440
Query: 361 EQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNS-- 418
E S T + H + L + S GE ++ P S + + P+ ++
Sbjct: 4441 EASTPVHSSTGSPHTT-------LSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFV 4493
Query: 419 EGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSAS-PEPEPPPTNKWQLDNW 477
E + S SS + S+ S + S S + + P +A+ P P T+
Sbjct: 4494 ELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS-----GL 4548
Query: 478 LNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNS---YTDTSGPKETS--------- 525
+ + + SP S+ + P S G E T +S +T +S P TS
Sbjct: 4549 VEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSY 4608
Query: 526 ---------------SATPGR-DSKTIQKGSESGRGRQKSPAQS-------DSTTQRRTV 562
S T GR + T S+ G PA+S +STT +
Sbjct: 4609 HSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISS 4668
Query: 563 GKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPR 622
G + A + P GL +S T SS P++ A++ + SSP
Sbjct: 4669 GSMETT-ALPGSTTTP--GLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPV 4725
Query: 623 PTA---------------EKKKYKSTSKSSQKSREIIETDTSSSDSDESE---------- 657
TA E Y S+ S+Q + E+ T+S S+ES
Sbjct: 4726 ATATTPSPARSTTSGLVEESTAYHSSPGSTQ-TMHFPESSTASGRSEESRTSHSSTTHTI 4784
Query: 658 SLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPD 709
S PPS+ + E P S+ + F + + +E + S PD
Sbjct: 4785 SSPPSTTSALVEEPTSYHSSPGSI--ATTHFPESSTTSGRSEESTASHSSPD 4834
Score = 58.2 bits (139), Expect = 5e-08
Identities = 152/692 (21%), Positives = 244/692 (35%), Gaps = 110/692 (15%)
Query: 70 SIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQS-QKRSSGLQ 128
S + +P PS EKS + R S + PA +TS + SS
Sbjct: 2503 SSTETTTLPGSPTTPSLSEKSTTFYTSPR-------SPDATLSPATTTSSGVSEESSTSH 2555
Query: 129 SGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGS---------------SSRKKGQHGSEH 173
S S T+A S T RH S+++ GS S H S
Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPG 2615
Query: 174 SKSRSSSPGKPQAVS--SLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSG 231
S + SPG A+S +++ S G+ H + + S +A+ +RV S+G
Sbjct: 2616 STDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEAS----TRVHSSTG 2671
Query: 232 QHSTQSFP-----PSLMSKSNSMLQKP-TAYVRPMDGQESMEPKLSSEHYSSQSHGNSMT 285
T P P L +S + P + + P + P S Y +S G++ T
Sbjct: 2672 SPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTY-HRSPGSTPT 2730
Query: 286 ELKPSS---KAHLTKLKIPSQPLDASASGDVSC------------------VDEILKEMT 324
P+S H K I DAS + S EI
Sbjct: 2731 THFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPG 2790
Query: 325 HSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDL 384
+ P L+ T + P + ++ G GE+ + S+ + H + S
Sbjct: 2791 STTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTT 2850
Query: 385 KLSSSED----SDGEQDCDKTM-PRSTPGS--NSEPSHHNSEGADNS------------- 424
S E S + T+ PRST S EP+ +S A
Sbjct: 2851 PGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGL 2910
Query: 425 RDDSSSHSGSESSSGSDSESESSSSD---SEANEPSQSASPEPEPPPTNKWQLDNWLNKV 481
++S++ GS +S+ + + +++D PS S S P + +
Sbjct: 2911 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARS-TTSGLVGES 2969
Query: 482 NPHKVSPASSVDSNIPSSQGYKKEGREQGT----GNSYTDTSGPKETSSATPGRDSKTIQ 537
P ++SP+S+ + +P S + T S T P T+S+ +S T
Sbjct: 2970 TPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST-- 3027
Query: 538 KGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMP 597
S S G + A DSTT T G Q E A+ +G +E + S+
Sbjct: 3028 --SHSQPGSTHTTAFPDSTT---TSGLSQ----EPTASHSSQG----STEATLSPGSTTA 3074
Query: 598 SSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSS------ 651
SS + +T P E+ P T ++++ + + + T T +S
Sbjct: 3075 SSLGQQSTTFHSSPG-DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGL 3133
Query: 652 --DSDESESLPPSSQ-TPKYPESNRTPVKPSS 680
+S +S P SS TP P + PV+ S+
Sbjct: 3134 QEESTTFQSWPSSSDTTPSPPGTTAAPVEVST 3165
Score = 57.0 bits (136), Expect = 1e-07
Identities = 197/943 (20%), Positives = 318/943 (33%), Gaps = 147/943 (15%)
Query: 76 AIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAP---STSQSQKRSSGLQSGHS 132
+IP T + + P+ H S +T P +TS + S+ + S
Sbjct: 341 SIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTG 400
Query: 133 SQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNS 192
S T+ SS T G+ +S+ +S +S S K ++ P SS +
Sbjct: 401 SPHTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSP---SSTPT 457
Query: 193 SH-SRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQ 251
+H S S HS+E P S +T + PP S ++ ++
Sbjct: 458 THFSASSTTLGHSEES------------------TPVHSSPVATATTPPPARSATSGHVE 499
Query: 252 KPTAYVRPMDGQESM---EPKLSSEH-------YSSQSHGNSMTELKPSSKAHLTKLKIP 301
+ TAY R ++M E +S H + S +H S T ++ AH T
Sbjct: 500 ESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAH-TSYHSS 558
Query: 302 SQPLDASASGDVSCVDEILKE--MTHSWPPPLTAIHTPCKTEPS-----KFPFP-TKESQ 353
+ + D S + +E +HS P + P + PS P P + S
Sbjct: 559 LGSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSM 618
Query: 354 QSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEP 413
++ G + S+ S S D L +S S G + + T S PGS
Sbjct: 619 ETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSE-ESTTSHSRPGSTHTT 677
Query: 414 SHHNSEGADN-SRDDSSSHSG---SESSSGSDSESESSSSDSEANEPSQSASPEPEPPPT 469
+ S S++ ++SHS ++++ S + SS S+ S E P
Sbjct: 678 AFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPD 737
Query: 470 NKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATP 529
N L P S S + P+ + QG ++ K+T A P
Sbjct: 738 NT-TASGLLEASMPVHSSTRSPHTTLSPAGSTTR-----QGESTTFHSWPSSKDTRPAPP 791
Query: 530 GRDSKTIQKGSESGRGRQKSPAQ------------SDSTTQRRTVGKKQPKKAEKAAAEE 577
S ++ + S P +STT + G Q ++
Sbjct: 792 TTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 851
Query: 578 PRG--GLKIESETPVDLASS---------MPSSRHKA--ATKGSRKPNIKKESKSSPRPT 624
RG S T ++S+ P+S H + +T + P+ S S T
Sbjct: 852 GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 911
Query: 625 AEKKKYKSTS-----KSSQKSREIIETDTS--SSDSDESESLPPSSQTP----------K 667
A +T S S + E+ TS SS S E+ +LP S+ TP
Sbjct: 912 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHS 971
Query: 668 YPESNRTPVKPSS-----VEEEDSFFRQRMFS------------PMEEKELLSPLSEPDD 710
P S T + P+S V EE + R R S P + + S P
Sbjct: 972 SPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 1031
Query: 711 RYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKV---SNKGKRK 767
+ + + T P + + G + A E SN G
Sbjct: 1032 TDTTL--LPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 1089
Query: 768 HKNEDDNRA------------SESKKPKTEDKNSAGHKPSSNRESSK-QSAAKEKDLLPS 814
D+ S + P+T ++ P ES+ Q+ PS
Sbjct: 1090 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 1149
Query: 815 P----AGPV---------PSKDPKTEHGSRKRTI--SQSSSLKSSSNSNKETSGSSKNSS 859
P PV P P T + T S+ S++ SS T+ SS +S+
Sbjct: 1150 PPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHST 1209
Query: 860 STSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPR 902
++ + + T + S S E+ S+++ A T S PR
Sbjct: 1210 TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPR 1252
Score = 56.2 bits (134), Expect = 2e-07
Identities = 175/920 (19%), Positives = 294/920 (31%), Gaps = 147/920 (15%)
Query: 72 PKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGH 131
P+ P + P +S F+ +H TP P+ +T+ ++ ++ +S
Sbjct: 1116 PRTTLSPASSTSPGLQGESTA--FQTHPASTHT----TPSPPSTATAPVEESTTYHRSPG 1169
Query: 132 SSQRTSAGSSSGTNSSGQR----HDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAV 187
S+ T +SS T+ ++ H + + SS G S + SPG + +
Sbjct: 1170 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE-I 1228
Query: 188 SSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSN 247
++L S + ++ + + SPR P S G+ ST S
Sbjct: 1229 TTLPGSTTTPGLSEASTTFYS---SPRSPTTTLSPASMTSLGVGEESTTS---------- 1275
Query: 248 SMLQKPTAYVRPMDGQESMEPKLSSEHYS--SQSHGNSMTELKPSSKAHLTKLKIPSQPL 305
+P + + + P LS E + S S G++ T + P S + P+
Sbjct: 1276 --RSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFH 1333
Query: 306 DASASGDVSCVDEI-----LKEMTHSWPP---------PLTAIHTPCKTEPSKFPF---- 347
AS + E L E + ++P P T E + FP
Sbjct: 1334 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 1393
Query: 348 ------PTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKT 401
P + + G R +PS T S L S+ + D T
Sbjct: 1394 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 1453
Query: 402 MPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSAS 461
+ +T S+ + E + + S+H+ + S + S+ + S +++ S A+
Sbjct: 1454 LSPATTTSSGV----SEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT 1509
Query: 462 PEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGP 521
P + + +P D I S TG+ +T T P
Sbjct: 1510 LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHT-TLTP 1568
Query: 522 KETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKA--AAEEPR 579
++SA +S T Q S P + + + T +P +A
Sbjct: 1569 ASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTT 1628
Query: 580 GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQK 639
G ES T S P AT + P S PT TS S
Sbjct: 1629 LGRSEESTT----VHSSPG-----ATGTALFPTRSATSVLVGEPT--------TSPISSG 1671
Query: 640 SREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS--VEEEDSFFRQRMFS--- 694
S E S++ + SE +P+ P++ +P +S V EE + R S
Sbjct: 1672 STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHT 1731
Query: 695 ---------PMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVP 745
P +E + S P + + P + P E +P
Sbjct: 1732 TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLP 1791
Query: 746 EKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSA 805
+ T +AS V + H + AG ++ QS
Sbjct: 1792 DNTTASGLLEASTPVHSSTGSPHTT----------------LSPAGSTTRQGESTTFQSW 1835
Query: 806 AKEKDLLPSPAGPV-------------PSKDPKTEHGSRKRTISQS-------------- 838
KD +P+P PS P T + T+ +S
Sbjct: 1836 PSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATA 1895
Query: 839 ----------SSLKSSSNSNKETSGSSKN----SSSTSKQKKTEGKTSSSSKEVKEKAPS 884
S L S + + GS++ SST+ + E +TS SS +P
Sbjct: 1896 TTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPP 1955
Query: 885 SSSNCPPSAPTLDSSKPRRT 904
S+++ PT S P T
Sbjct: 1956 STTSALVEEPTSYHSSPGST 1975
Score = 56.2 bits (134), Expect = 2e-07
Identities = 178/901 (19%), Positives = 311/901 (34%), Gaps = 129/901 (14%)
Query: 72 PKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGH 131
P+ P + P +S F+ +H TP P+ +T+ ++ ++ +S
Sbjct: 3756 PRTTLSPASSTSPGLQGESTA--FQTHPASTHT----TPSPPSTATAPVEESTTYHRSPG 3809
Query: 132 SSQRTSAGSSSGTNSSGQR----HDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAV 187
S+ T +SS T+ ++ H + + SS G S + SPG + +
Sbjct: 3810 STPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE-I 3868
Query: 188 SSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSN 247
++L S + ++ + + SPR P S G+ ST S
Sbjct: 3869 TTLPGSTTTPGLSEASTTFYS---SPRSPTTTLSPASMTSLGVGEESTTS---------- 3915
Query: 248 SMLQKPTAYVRPMDGQESMEPKLSSEHYS--SQSHGNSMTELKPSSKAHLTKLKIPSQPL 305
+P + + + P LS E + S S G++ T + P S + + P+
Sbjct: 3916 --RSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTFH 3973
Query: 306 DASASGDVSCVDEI-----LKEMTHSWPP---------PLTAIHTPCKTEPSKFPF---- 347
AS + E L E + ++P P T E + FP
Sbjct: 3974 SRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGS 4033
Query: 348 ------PTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKT 401
P + + G R +PS T S L S+ + D T
Sbjct: 4034 TGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 4093
Query: 402 MPRSTPGSN--SEPSH--HNSEGADNSR--DDSSSHSG-------SESSSGSDSESESSS 448
+ +T S+ SE S H+ G+ ++ DS++ SG S SS GS + S
Sbjct: 4094 LSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPG 4153
Query: 449 SDSEANEPSQSASPEPEPPPTNKWQL-DNWLNKVNPHKVSPASSVDSNI--------PSS 499
S + ++ QS + P T L D+ + +P S ++ +S
Sbjct: 4154 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS 4213
Query: 500 QGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQR 559
G ++E + S +DT+ +++A P S T R S + +
Sbjct: 4214 TGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHS-------RPSSTPTTHFSASS 4266
Query: 560 RTVGKKQPKKAEKAAAEEPRGGL-KIESETPVDLASSMPSSRHKAATKGSRKPNIKKESK 618
T+G+ + ++ L S T V + S +T+ + P +
Sbjct: 4267 TTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAG 4326
Query: 619 SSPRPTAEKKKYKSTSKSSQKSREIIETDTS--SSDSDESESLPPSSQTPKYPESNRTPV 676
S + T + S+ +S + T +S S +S S S P S T +P S P
Sbjct: 4327 LSEKSTT----FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMP- 4381
Query: 677 KPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEP 736
V +E + SP LSP S P + P
Sbjct: 4382 ---GVSQESTASHS---SPGSTDTTLSPGSTTASSLG-------------PESTTFHSSP 4422
Query: 737 PKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSS 796
E +P+ T +AS V + H ++ + T ++ K ++
Sbjct: 4423 GSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTT 4482
Query: 797 NRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQS-----------SSLKSSS 845
+ SA E L + + PS P T + T+ +S ++ + S
Sbjct: 4483 PAPPTTTSAFVE---LSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPS 4539
Query: 846 NSNKETSGSSKNSS-------STSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDS 898
+ TSG + S+ ST E T+S E + SS+++ SAP+ S
Sbjct: 4540 PARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTS 4599
Query: 899 S 899
+
Sbjct: 4600 A 4600
Score = 55.1 bits (131), Expect = 4e-07
Identities = 183/914 (20%), Positives = 306/914 (33%), Gaps = 147/914 (16%)
Query: 69 RSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQ 128
RS V +PT S ++ F + S + + T +P+++Q+ ++
Sbjct: 3958 RSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 4017
Query: 129 SGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVS 188
+ + T+ SSSG S+G + SG S S ++ PG P
Sbjct: 4018 ADLGEESTTFPSSSG--STGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSP-TTP 4074
Query: 189 SLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPF-----SSGQHS------TQS 237
SL+ + + SPR PDA + SS HS T +
Sbjct: 4075 SLSEKSTTFY------------TSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA 4122
Query: 238 FPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTK 297
FP S + ++ + Q+PT Q S E LS ++ S G T S T
Sbjct: 4123 FPDS--TTTSGLSQEPTT---SHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETT 4177
Query: 298 LKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKT-----EPSKFPFPTKES 352
L P D SG V THS L TP + + F + S
Sbjct: 4178 LL----PDDTITSGLVEA-----STPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPS 4228
Query: 353 QQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE 412
+ P + S + S+ S+S + G + + T S+PG+
Sbjct: 4229 SSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE-ESTTVHSSPGATGT 4287
Query: 413 PSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKW 472
+ + A + + S S S + S++ + +E S + P P T
Sbjct: 4288 -ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT-- 4344
Query: 473 QLDNWLNKVNPHKVSPASSVDSNIP--SSQGYKKEGREQGTG-NSYTDTSGPKETSSAT- 528
+SPAS+ S + S+ + + G T S T G + S+A+
Sbjct: 4345 -------------LSPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASH 4391
Query: 529 --PGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIES 586
PG T+ GS + S +STT + G + GL +E+
Sbjct: 4392 SSPGSTDTTLSPGSTTA-----SSLGPESTTFHSSPGSTETTLLPDNTTAS---GL-LEA 4442
Query: 587 ETPVDLASSMPSSRHKAATKGSRK---------PNIKKESKSSPRPTAEKKKYKSTSKSS 637
TPV ++ P + A +R+ PN K + + P T+ + +TS S
Sbjct: 4443 STPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGS 4502
Query: 638 QKSREIIETDTSSSDSDESE----------------------------------SLPPSS 663
S SS+ SE S P S+
Sbjct: 4503 PSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGST 4562
Query: 664 QTPKYPESNRTPVK-PSSVEEEDSFFRQRMFSPMEEKELL--------SPLSEPDDRYPL 714
QT +PESN T + S S +P L+ SP S +P
Sbjct: 4563 QTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFP- 4621
Query: 715 IVKIDLNLLTRIPGKPYKETEPPKGEKKN----VPEKHTREA--QKQASEKVSNKGKRKH 768
D + + G+ + T + +P + T + + +S+
Sbjct: 4622 ----DSSTTS---GRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETT 4674
Query: 769 KNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPV-PSKDPKTE 827
+ T +S P+++ +S + + ++ + PV + P
Sbjct: 4675 ALPGSTTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPA 4734
Query: 828 HGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSS 887
+ + +S++ SS S T SST+ + E +TS SS +P S++
Sbjct: 4735 RSTTSGLVEESTAYHSSPGS---TQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTT 4791
Query: 888 NCPPSAPTLDSSKP 901
+ PT S P
Sbjct: 4792 SALVEEPTSYHSSP 4805
Score = 53.9 bits (128), Expect = 9e-07
Identities = 124/611 (20%), Positives = 210/611 (34%), Gaps = 87/611 (14%)
Query: 102 SHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSG- 160
S +SK T P +TS + S+ SS T+ S+S T + G+ + + ++S
Sbjct: 4474 SWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASST-TLGRSEESTTVHSSPV 4532
Query: 161 ------SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGND----HHSKEHQRS 210
S +R E S + SSPG Q + S+ + G + H S H S
Sbjct: 4533 ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTIS 4592
Query: 211 KSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKL 270
+P A + P+ S G +T FP S + S +ES
Sbjct: 4593 SAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRS--------------EES----- 4633
Query: 271 SSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPP 330
++ H S + G + +P++ S +L E T S P
Sbjct: 4634 TASHSSQDATGT---------------IVLPAR----------STTSVLLGESTTS---P 4665
Query: 331 LTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSE 390
+++ P P + + F + +PS T H S+S
Sbjct: 4666 ISSGSMETTALPGSTTTPGLSEKSTTFHS------SPSSTPTTH-----------FSASS 4708
Query: 391 DSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSD-SESESSSS 449
+ G + T+ S + + PS S + + ++ HS S+ ES ++S
Sbjct: 4709 TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASG 4768
Query: 450 DSEANEPSQSASPEP-EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGRE 508
SE + S S++ PP+ L + + + SP S ++ P S E
Sbjct: 4769 RSEESRTSHSSTTHTISSPPSTTSAL---VEEPTSYHSSPGSIATTHFPESSTTSGRSEE 4825
Query: 509 QGTGNSYTDTSG--PKETSSATPGR--DSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK 564
+S DT+G P T GR +S T S S A + + + T+
Sbjct: 4826 STASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILY 4885
Query: 565 KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKS-SPRP 623
+ ++ + I E P L S S+ A + + +ES + +P
Sbjct: 4886 SSSRSPDQTLSPASMTSSSISGE-PTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKP 4944
Query: 624 TAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEE 683
+ + S ++ + T S S S P S+ P E + T E
Sbjct: 4945 GSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEESTTFYSSPGSTE 5004
Query: 684 EDSFFRQRMFS 694
+F S
Sbjct: 5005 TTAFSHSNTMS 5015
Score = 45.1 bits (105), Expect = 4e-04
Identities = 91/404 (22%), Positives = 139/404 (34%), Gaps = 62/404 (15%)
Query: 76 AIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQR 135
A+P T P EKS H S TP ++S + RS + HSS
Sbjct: 4675 ALPGSTTTPGLSEKSTT---------FHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPV 4725
Query: 136 TSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAV----SSLN 191
+A + S S+ SG H SSPG Q + SS
Sbjct: 4726 ATATTPSPARST----------TSGLVEESTAYH---------SSPGSTQTMHFPESSTA 4766
Query: 192 SSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSN---- 247
S S H S H S P A + P+ S G +T FP S +
Sbjct: 4767 SGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEES 4826
Query: 248 --SMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPL 305
S T + P+ + +++ S G+ T L +S A L S L
Sbjct: 4827 TASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTL--ASTATTPGLSAKSTIL 4884
Query: 306 -DASASGDVSCVDEILKEMTHSWPPPLTAIHTPCK-TEPSKFPFPTKESQQSNFGTGEQK 363
+S S D + + + S P T++++ + T + FP T S S
Sbjct: 4885 YSSSRSPDQTLSPASMTSSSISGEP--TSLYSQAESTHTTAFPASTTTSGLS-------- 4934
Query: 364 RYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADN 423
+++ H + L S S Q+ T P S PGS S
Sbjct: 4935 ----QESTTFHSKPGSTETTLSPGSITTSSFAQEF--TTPHSQPGSALSTVSPASTTVPG 4988
Query: 424 SRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPP 467
++S++ S S+ + + S S++ SQ ++P P+ P
Sbjct: 4989 LSEESTTFYSSPGSTETTAFSHSNTMSIH----SQQSTPFPDSP 5028
Score = 44.3 bits (103), Expect = 7e-04
Identities = 136/634 (21%), Positives = 219/634 (34%), Gaps = 76/634 (11%)
Query: 73 KLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHS 132
++ +P T P E S + R S T + PA TS S
Sbjct: 2784 EITTLPGSTTTPGLSEASTTFYSSPR-------SPTTTLSPASMTSLGVGEESTTSRSQP 2836
Query: 133 SQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNS 192
S S + T + G + + +S S + S + S +P S +
Sbjct: 2837 GSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVF--PRSTTTSVRGEEPTTFHSRPA 2894
Query: 193 SHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSS-----GQHSTQSFPPSLMSKSN 247
S + + + +S P + + + +P + G+ ST +FP S S S
Sbjct: 2895 STHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEEST-TFPSS--SGST 2951
Query: 248 SMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDA 307
P ES +LS + + S T S K+ T P P DA
Sbjct: 2952 GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKS-TTFYTSPRSP-DA 3009
Query: 308 SASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNP 367
+ S + + +E + T+ P T + FP T S S T
Sbjct: 3010 TLSPATTTSSGVSEESS-------TSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGS 3062
Query: 368 SKT--SNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSN----SEPSHHNSEGA 421
++ S G + S L S D E +P T S S P+H ++
Sbjct: 3063 TEATLSPGSTTASSLGQQSTTFHSSPGDTETTL---LPDDTITSGLVEASTPTHSSTGSL 3119
Query: 422 DNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKV 481
+ +SS S + +S SSSD+ + P +A+P +
Sbjct: 3120 HTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP---------------VEVS 3164
Query: 482 NPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKG-- 539
+ P+S+ ++ +S E T +S +G ++ P R + ++ G
Sbjct: 3165 TTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATG----TALFPTRSATSVLVGEP 3220
Query: 540 --SESGRGRQKSPAQSDSTT-----QRRTVGKKQPKKAEK--AAAEEPRGGLKIESETPV 590
S G ++ A STT ++ T P+ + + A G+ ES T
Sbjct: 3221 TTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTT-- 3278
Query: 591 DLASSMPSSRHKAATKGS-RKPNIKKE---SKSSPRPTAEKKKYKSTSKSSQKSREIIET 646
+ S P S H A GS P + +E S SSP T ST+ SS T
Sbjct: 3279 --SHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPES--TT 3334
Query: 647 DTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS 680
S S E+ LP ++ E++ TPV S+
Sbjct: 3335 FHSGPGSTETTLLPDNTTASGLLEAS-TPVHSST 3367
>gi|52426735 ankyrin 2 isoform 1 [Homo sapiens]
Length = 3957
Score = 77.4 bits (189), Expect = 7e-14
Identities = 210/997 (21%), Positives = 347/997 (34%), Gaps = 153/997 (15%)
Query: 87 DEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNS 146
DE+ + R G K T P P+ S S K S+R + GS S
Sbjct: 1779 DEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLK----------SERHAPGSPSPKT- 1827
Query: 147 SGQRHDRESYNNSGSSSRKKGQHG--SEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHS 204
+RH ++ SSS K +H S SK+ SP P A + +S S S + HS
Sbjct: 1828 --ERH------STLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHS 1879
Query: 205 KEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQE 264
+K+ R + R P S T PP +S S + P + +
Sbjct: 1880 PVSPSTKTERHSPVSSTKTERHPPVSPSGKTDKRPP--VSPSGRTEKHPPVSPGRTEKRL 1937
Query: 265 SMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASAS-GDVSCVDEILKEM 323
+ P ++ + S + P S + T+ + P P + + V E++K
Sbjct: 1938 PVSPSGRTDKHQPVSTAGKTEKHLPVSPSGKTEKQPPVSPTSKTERIEETMSVRELMKAF 1997
Query: 324 THSWPPPLTAI----HTPCK-----------TEPSKFPFPTKESQQSNFGTGEQKRYNPS 368
P H K E K P T+ Q ++
Sbjct: 1998 QSGQDPSKHKTGLFEHKSAKQKQPQEKGKVRVEKEKGPILTQREAQKTENQTIKRGQRLP 2057
Query: 369 KTSNGHQSKSMLKDDLKLSSSEDSDG-EQDCDKTMPRSTPGSNSEPSHHNSE-----GAD 422
T + + + + + + G E+ +P E SH SE AD
Sbjct: 2058 VTGTAESKRGVRVSSIGVKKEDAAGGKEKVLSHKIPEPVQSVPEEESHRESEVPKEKMAD 2117
Query: 423 NSRDDSSSHSGSESSSGSDSE---SESSSSD-------SEANEPSQSASPEPEPPPTN-K 471
D S +S SE E +D SE E +Q + P N
Sbjct: 2118 EQGDMDLQISPDRKTSTDFSEVIKQELEDNDKYQQFRLSEETEKAQLHLDQVLTSPFNTT 2177
Query: 472 WQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEG--------REQGTGNSYTDTSGPKE 523
+ LD ++ P + ++D SS+ K EG +GT ++ S E
Sbjct: 2178 FPLDYMKDEFLPALSLQSGALDG---SSESLKNEGVAGSPCGSLMEGTPQISSEESYKHE 2234
Query: 524 TSSATPGRDSKTIQ---KGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRG 580
+ TP +++ K SE G K ++++TT+ R+ K+ P + E RG
Sbjct: 2235 GLAETPETSPESLSFSPKKSEEQTGETKESTKTETTTEIRS-EKEHPTTKDITGGSEERG 2293
Query: 581 GLKIE-SETPVDLASSMPSSRHKAATKGSRKPNIKKE------------SKSSPRPTAEK 627
E SET + S K AT GS K K +K +P E+
Sbjct: 2294 ATVTEDSETSTE-------SFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEE 2346
Query: 628 ----KKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEE 683
+ ++ S+ K++ E S++ SDE+++LP + K T KP V
Sbjct: 2347 AACDEGQRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVK--TDTGTESKPQGVIR 2404
Query: 684 EDSFFRQRMFSPMEEKELL------------------SPLSEPDDRYPLIVKIDLNLLTR 725
+ P + E+L SP+ E + + ++ + L
Sbjct: 2405 SPQGLELAL--PSRDSEVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKE 2462
Query: 726 IPGKPYKETEP--PKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK--NEDDNRASESKK 781
P + E+ P PK + P A +E ++ + + + D A +
Sbjct: 2463 SPCRDSLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGSAEDDSL 2522
Query: 782 PKTEDKNSAGHKP-----SSNRESSKQSAAKEKDL-LPSPAG-PVPSKDPKTEHGSRKRT 834
+T S+G P S+ E S + K D+ P PA +++ +E+G +KR
Sbjct: 2523 EQTSLMESSGKSPLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAEEDDSENGEKKRF 2582
Query: 835 ISQSSSLKSSSNSN--KETSGSSKNSSSTSKQKKTEGKTSSS------SKEVKEKAPSSS 886
+ K + E +K K+ K E +SSS S +V E + S
Sbjct: 2583 TPEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHTGS 2642
Query: 887 SNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAV 946
P L +S+ R+ S+ E +LK AD+ L
Sbjct: 2643 GEDESGVPVLVTSESRKVS--------SSSESEPELAQLKKGADS---------GLLPEP 2685
Query: 947 VSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKL 983
V ++ + L + + SP + + V +YT K+
Sbjct: 2686 VIRVQPPSPLPSSMDSNSSPEEVQFQPVVSKQYTFKM 2722
Score = 55.8 bits (133), Expect = 2e-07
Identities = 146/741 (19%), Positives = 252/741 (34%), Gaps = 140/741 (18%)
Query: 222 SPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHG 281
SP + FS + Q+ +K+ + T +R E P S+ G
Sbjct: 2243 SPESLSFSPKKSEEQTGETKESTKTET-----TTEIR----SEKEHPTTKDITGGSEERG 2293
Query: 282 NSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTE 341
++TE +S K P D S C + P LT C
Sbjct: 2294 ATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTE-EAACDEG 2352
Query: 342 PSKFPFPTKESQ-----QSNFGTGEQKRYNPS-----KTSNGHQSK--SMLKDDLKLSSS 389
F ++Q Q + T ++ + P KT G +SK +++ L +
Sbjct: 2353 QRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELA 2412
Query: 390 EDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESES--S 447
S D + + + SH +S A +D+SSH +S S +
Sbjct: 2413 LPSR-----DSEVLSAVADDSLAVSHKDSLEASPVLEDNSSHKTPDSLEPSPLKESPCRD 2467
Query: 448 SSDSEANEPSQSA----SPEPEPPPTNKWQLDNWLNKVNPHKV-SPASSVD------SNI 496
S +S EP A S P P K +L + V + P S + +++
Sbjct: 2468 SLESSPVEPKMKAGIFPSHFPLPAAVAKTELLTEVASVRSRLLRDPDGSAEDDSLEQTSL 2527
Query: 497 PSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGR---DSKTIQKGSESGRGRQKSPAQS 553
S G + + + PK T +TP + SE+G ++ +P +
Sbjct: 2528 MESSGKSPLSPDTPSSEEVSYEVTPKTTDVSTPKPAVIHECAEEDDSENGEKKRFTPEEE 2587
Query: 554 --------------DSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSS 599
+ +++ KK+PK+ E +++ +P ++ + P S
Sbjct: 2588 MFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPKHTGSG---- 2643
Query: 600 RHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESL 659
+ ES T+E +K S+S+S + ++ + S + +
Sbjct: 2644 --------------EDESGVPVLVTSESRKVSSSSESEPELAQLKKGADSGLLPEPVIRV 2689
Query: 660 PPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKID 719
P S P +SN +P + F P+ K+ ++E
Sbjct: 2690 QPPSPLPSSMDSNSSP-------------EEVQFQPVVSKQYTFKMNEDT---------- 2726
Query: 720 LNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASES 779
+ EP K E++ E H E + S + ++ K + D
Sbjct: 2727 -------------QEEPGKSEEEKDSESHLAEDRHAVSTEAEDRSYDKLNRDTD------ 2767
Query: 780 KKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAG------PVPSKDPKTEHGSRKR 833
+PK D GH + SS SAA L SP G PV K+ G+ ++
Sbjct: 2768 -QPKICD----GHGCEAMSPSS--SAAPVSSGLQSPTGDDVDEQPVIYKESLALQGTHEK 2820
Query: 834 T-------ISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTE---GKTSSSSKEVKEKAP 883
+S++ S ++ S +S SS S+ K+ + TSS K K
Sbjct: 2821 DTEGEELDVSRAESPQADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTD 2880
Query: 884 SSSSNCPPSAPTLDSSKPRRT 904
+ N P P+ DSS +T
Sbjct: 2881 ETFENLPKDCPSQDSSITTQT 2901
Score = 42.7 bits (99), Expect = 0.002
Identities = 71/365 (19%), Positives = 126/365 (34%), Gaps = 69/365 (18%)
Query: 582 LKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSR 641
+K+ + D++ S + K K + +E P E+ K + +K
Sbjct: 1515 IKMTAILTTDVSDKAGSIKVKELVKAA------EEEPGEPFEIVERVK-----EDLEKVN 1563
Query: 642 EIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPME---- 697
EI+ + T + D +S S E V +EE R +P+E
Sbjct: 1564 EILRSGTCTRDESSVQS---SRSERGLVEEEWVIVSDEEIEEA------RQKAPLEITEY 1614
Query: 698 -------EKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEK--------- 741
+KE+ + + + DLN +P + + + G+K
Sbjct: 1615 PCVEVRIDKEIKGKVEKDSTGLVNYLTDDLNTCVPLPKEQLQTVQDKAGKKCEALAVGRS 1674
Query: 742 -----KNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSS 796
K++P T+ QKQ + K + K E +K K E ++ K
Sbjct: 1675 SEKEGKDIPPDETQSTQKQHKPSLGIKKPVRRK------LKEKQKQKEEGLQASAEKAEL 1728
Query: 797 NRESSKQSAAKEKDLLPSPAGPVPSKDP---KTEHGSRKRTISQSSS------------- 840
+ SS++S ++ L P P V + P +T GS K +
Sbjct: 1729 KKGSSEESLGEDPGLAPEPLPTVKATSPLIEETPIGSIKDKVKALQKRVEDEQKGRSKLP 1788
Query: 841 --LKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDS 898
+K + K+T+ ++S S + + S S K + SSS+ P S
Sbjct: 1789 IRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKTERHSTLSSSAKTERHPPVSPS 1848
Query: 899 SKPRR 903
SK +
Sbjct: 1849 SKTEK 1853
Score = 39.7 bits (91), Expect = 0.017
Identities = 40/163 (24%), Positives = 65/163 (39%), Gaps = 8/163 (4%)
Query: 740 EKKNVPEKHTREAQKQASE-KVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPS--S 796
+K +K + QK S+ + KGK + +R + P + + A PS +
Sbjct: 1768 DKVKALQKRVEDEQKGRSKLPIRVKGKEDVPKKTTHRPHPAASPSLKSERHAPGSPSPKT 1827
Query: 797 NRESSKQSAAKEKDLLP-SPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSS 855
R S+ S+AK + P SP+ P + +R SSS K+ +S S +
Sbjct: 1828 ERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTERHSPASSSSKTEKHSPVSPSTKT 1887
Query: 856 KNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSS----NCPPSAP 894
+ S S K S S + ++ P S S PP +P
Sbjct: 1888 ERHSPVSSTKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPVSP 1930
Score = 39.3 bits (90), Expect = 0.022
Identities = 189/944 (20%), Positives = 337/944 (35%), Gaps = 154/944 (16%)
Query: 4 EDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYD-EM 62
E R V E E ++++G D S L EP L S + S + +
Sbjct: 2656 ESRKVSSSSESEPELAQLKKGAD-----SGLLPEPVIRVQPPSPLPSSMDSNSSPEEVQF 2710
Query: 63 KDFIGDRSIPKLVAIPKPTVPPSADEK-SNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQ 121
+ + + K+ + S +EK S + E RH S ++ + T Q +
Sbjct: 2711 QPVVSKQYTFKMNEDTQEEPGKSEEEKDSESHLAEDRHAVSTEAEDRSYDKLNRDTDQPK 2770
Query: 122 KRSSGLQSGHSSQRTSAGSSSGTNSSGQRHD------------RESYNNSGSSSRKKGQH 169
+ GH + S SS+ SSG + +ES G+ +K
Sbjct: 2771 -----ICDGHGCEAMSPSSSAAPVSSGLQSPTGDDVDEQPVIYKESLALQGT--HEKDTE 2823
Query: 170 GSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEH----------QRSKSPRDPDAN 219
G E SR+ SP S +SS S H KE Q+++ + +
Sbjct: 2824 GEELDVSRAESPQADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEVTKTDETF 2883
Query: 220 WDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPK---LSSEHYS 276
+ P P +TQ+ S+ + + + Y + P SSE
Sbjct: 2884 ENLPKDCPSQDSSITTQTDRFSMDVPVSDLAENDEIYDPQITSPYENVPSQSFFSSEESK 2943
Query: 277 SQSHGNSMTELKPSSKAHLTKLKIPSQPL--DASASGDV---------------SCVDEI 319
+Q+ N T SS+ + + P + + +S+SG V S +
Sbjct: 2944 TQTDANHTTSFH-SSEVYSVTITSPVEDVVVASSSSGTVLSKESNFEGQDIKMESQQEST 3002
Query: 320 LKEM-----THSWPPPLTAIHTPCKTEPSK----------------------FPFPTKES 352
L EM + S+ P ++A T + SK F KE
Sbjct: 3003 LWEMQSDSVSSSFEPTMSATTTVVGEQISKVIITKTDVDSDSWSEIREDDEAFEARVKEE 3062
Query: 353 QQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRS-----TP 407
+Q FG R + T + +++ ++ S ++ M RS T
Sbjct: 3063 EQKIFGLMVD-RQSQGTTPDTTPARTPTEEGTPTSEQNPFLFQEGKLFEMTRSGAIDMTK 3121
Query: 408 GSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSD-----------SESESSSS-DSEANE 455
S ++ S H + SR+++ S E ++G+D + SES + D EA+
Sbjct: 3122 RSYADESFHFFQIGQESREETLSEDVKEGATGADPLPLETSAESLALSESKETVDDEADL 3181
Query: 456 PSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSY 515
S E E P + QL++ + +S ++ + S G K Q TG+
Sbjct: 3182 LPDDVSEEVEEIPASDAQLNSQMG------ISASTETPTKEAVSVGTKDLPTVQ-TGD-I 3233
Query: 516 TDTSGPKETS---SATPG----RDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPK 568
SG K+ S S+ P D T+ + S RG + S ++++V +
Sbjct: 3234 PPLSGVKQISCPDSSEPAVQVQLDFSTLTRSVYSDRG---DDSPDSSPEEQKSVIEIPTA 3290
Query: 569 KAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKK 628
E E + KI T + PS+ ++++ ++ +E+K+ K
Sbjct: 3291 PMENVPFTESKS--KIPVRTMPTSTPAPPSAEYESSVSEDFLSSVDEENKADEAKPKSKL 3348
Query: 629 KYKSTSKSSQKSREIIETD---TSSSDSDESESLPPSSQTPKYPESN------RTPVKPS 679
K + ++ ++T T + + S+ P +++ +++ + PVK
Sbjct: 3349 PVKVPLQRVEQQLSDLDTSVQKTVAPQGQDMASIAPDNRSKSESDASSLDSKTKCPVKTR 3408
Query: 680 SVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYK-ETEPPK 738
S E ++ R+R EE EL SE P I+ L + +R + T P K
Sbjct: 3409 SYTETETESRER----AEELEL---ESEEGATRPKILTSRLPVKSRSTTSSCRGGTSPTK 3461
Query: 739 GEKKNVPEKHT------REAQKQASEKVSNKGKRKHKNE---DDNRASE------SKKPK 783
K++ + + E +AS+ V + + + E DD +S P
Sbjct: 3462 ESKEHFFDLYRNSIEFFEEISDEASKLVDRLTQSEREQEIVSDDESSSALEVSVIENLPP 3521
Query: 784 TEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTE 827
E ++S R +S + +P G ++DP+ E
Sbjct: 3522 VETEHSVPEDIFDTRPIWDESIETLIERIPDENGHDHAEDPQDE 3565
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
critical region 1 [Homo sapiens]
Length = 1400
Score = 76.6 bits (187), Expect = 1e-13
Identities = 146/794 (18%), Positives = 286/794 (36%), Gaps = 105/794 (13%)
Query: 153 RESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGND----------- 201
R S G+++ ++ Q E S S P P V S+ H H
Sbjct: 83 RYSCQMKGATTFQEYQKTGELSTSDHIFPLTPGLVYSIPFDHIVLHSGQRPPELPKSTEI 142
Query: 202 HHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMD 261
H K H + P S+ PP+ S+ NS Q +R
Sbjct: 143 HEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPT--SEENSSNQGKDPMIR--- 197
Query: 262 GQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKI-----------PSQPLDASAS 310
Q S++P S+ + +S G P SK + K +PL+ S S
Sbjct: 198 NQRSVDPADSTTTHK-ESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMS 256
Query: 311 GDVSCVDEILKEMTHSWPPPLTAIHTP--CKTEPSKFPFPTKESQQSNFGTGEQKRYNPS 368
L + + S T+ H +T+ FP K + S T + P
Sbjct: 257 --------TLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASK--TTYKTTGTPE 306
Query: 369 KTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDS 428
++ S++ + D L+ + + E + +S +EP+ H A+ + S
Sbjct: 307 ESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSL----AEPTEHGGRTANENNTPS 362
Query: 429 SSH---SGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDN---WLNKVN 482
+ + +++ + + S + +++ +++ +P P P N+ N L
Sbjct: 363 PAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFPAE 422
Query: 483 PHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSES 542
P + ++ ++ PS + G N+ + P E TP + KT +ES
Sbjct: 423 PTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAES 482
Query: 543 GRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHK 602
+++P +++TT P AE E R + + +P + ++ ++
Sbjct: 483 TEHGERTPLANENTT---------PSPAEPTENRE-RTANENTTPSPAGPTENRETTANE 532
Query: 603 AATKGSRKPNIKKES----KSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESES 658
T +P +E+ K++P P + + T +++K+ T +S+ ++ E
Sbjct: 533 KTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKT-----TSSSAEPTEHGER 587
Query: 659 LPPSSQ----TPKYPESNR-----TPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPD 709
P +++ +P P NR PS E ++ R +P+ ++ L+EP
Sbjct: 588 TPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDR----TPLANEKTTPSLAEPT 643
Query: 710 DRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHK 769
+ R P K T + E+ T A + + + + + +
Sbjct: 644 ENG-----------QRTPFANEKTTS--SSAEPTEHEERTPLANENTTPSPAEPTENRER 690
Query: 770 NEDDNRASESKKPKTEDKNSAGHK-------PSSNRESSKQSAAKEKDLLPSPAGP-VPS 821
++N P + +A K P+ NRE + P+ G P
Sbjct: 691 TANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPF 750
Query: 822 KDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEK 881
+ KT S + T + ++ N+ +G ++N T+ +K T + E +E+
Sbjct: 751 ANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTANEKTT--PFPAEPTENRER 808
Query: 882 APSSSSNCPPSAPT 895
+ ++ P+ PT
Sbjct: 809 TANENTTPSPAQPT 822
Score = 60.8 bits (146), Expect = 7e-09
Identities = 176/957 (18%), Positives = 349/957 (36%), Gaps = 121/957 (12%)
Query: 37 EPYKVTSKEDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFE 96
E + T DKL ++ +++ I + + +A P +A+E + P+ E
Sbjct: 312 EDSRTTVASDKLLTKTTK------NIQETISANELTQSLAEPTEHGGRTANENNTPSPAE 365
Query: 97 QRHGGSHQSSKWTPVGPAPSTSQSQK----RSSGLQSGHSSQRTSAGSSSGT---NSSGQ 149
+++ T + PA T ++ ++ +G + R + + T +
Sbjct: 366 PTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLFPAEPTE 425
Query: 150 RHDRESYNNSGSSSRKKGQHGSEHSKSRSS-SPGKPQA----------VSSLNSSHSRSH 198
+R + N+ S + +HG + ++ SP +P ++ +S+ S H
Sbjct: 426 HGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSAESTEH 485
Query: 199 GNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPT-AYV 257
G + SP +P N + ++ +++T S ++ + +K T + V
Sbjct: 486 GERTPLANENTTPSPAEPTENRER------TANENTTPSPAGPTENRETTANEKTTLSPV 539
Query: 258 RPMDGQESMEPKLSSEHYSSQSHGNSMT----ELKPSSKA----HLTKLKIPSQPLDASA 309
P + +E+ + ++ + + T E SS A H + + ++ S
Sbjct: 540 EPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSP 599
Query: 310 SGDVSCVDEILKEMTHSWP--PPLTAIHTPC---KTEPSKFPFPTKESQQSNFGTGEQKR 364
+ + E T P P TP KT PS PT+ Q++ F +K
Sbjct: 600 AEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPS-LAEPTENGQRTPFAN--EKT 656
Query: 365 YNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS 424
+ S H+ ++ L ++ S ++ ++ ++T +T S + P+ + A+
Sbjct: 657 TSSSAEPTEHEERTPLANENTTPSP--AEPTENRERTANENTTPSPAGPTENREMTANEK 714
Query: 425 RD-------DSSSHSGSESSSGSDSE-SESSSSDSEANEPSQSASPEP-----EPPPTNK 471
++ + +E ++ S +E +E+ ANE + S+S EP P N+
Sbjct: 715 TTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANE 774
Query: 472 WQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGR 531
+ L+ P + ++ + P + N+ + P E TP
Sbjct: 775 ---NTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLA 831
Query: 532 DSKTIQKGSESGRGRQKSPAQSDSTTQ---------RRTVGKKQPKKAEKAAAEEPRGGL 582
+ KT +E +++P ++ TT RT + + A E R
Sbjct: 832 NEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERT 891
Query: 583 KIESET--PVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPT---AEKKKYKSTS--- 634
E T P + + S+ ++ T +P +E ++ T AE +++ +
Sbjct: 892 ANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLM 951
Query: 635 ------------KSSQKSREIIET--DTSSSDSDESESLPPSSQTPKYPESNRTPVKPSS 680
+++ ++I T T+ S+S + + SS ++ T +S
Sbjct: 952 VDENLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTAS 1011
Query: 681 VEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDL------NLLTRIPGKPYKET 734
S + E + +SEP L ++ L N T T
Sbjct: 1012 EITMSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPTT 1071
Query: 735 EPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKP 794
G K + T A+ S ED ++++ E K
Sbjct: 1072 ASTSGSKNTTACEATMSETTIAAITAS---------EDTTVSTQTSVIAAESVPHTATKT 1122
Query: 795 SSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEH-----GSRKRTISQSSSLKSS--SNS 847
++ ++ SA K+ S PS P T S+ T S +SL ++ + +
Sbjct: 1123 PTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTT 1182
Query: 848 NKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRT 904
+K T+GS ++ST+ T T +S V E APS++ P A T +S P T
Sbjct: 1183 SKITAGSEIPTASTTDSATTAISTKASGTTV-ESAPSTAP--PTPAETTTASVPTTT 1236
Score = 55.5 bits (132), Expect = 3e-07
Identities = 130/724 (17%), Positives = 261/724 (36%), Gaps = 111/724 (15%)
Query: 18 NQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMKDFIGDRSIPKLVAI 77
N + +Q +FP ++ T+ + S + + D D+ + K
Sbjct: 277 NSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTE------DSRTTVASDKLLTKTTKN 330
Query: 78 PKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPS-----TSQSQKRSSGLQSGHS 132
+ T+ SA+E + HGG + TP P+ T+ S + +
Sbjct: 331 IQETI--SANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTEN 388
Query: 133 SQRTSAGSSSGTNSSGQRHDRESYNNSGSS--SRKKGQHGSEHSKSRSS-SPGKPQAVSS 189
+RT A ++ +G +RE N ++ + +HG + ++ SP +P
Sbjct: 389 RERT-ANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEP----- 442
Query: 190 LNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSM 249
+ H N++ + SP +P + + R PF++ + +T S S +
Sbjct: 443 --TEHGERTANEN------TTPSPAEPTEHGE---RTPFANDK-TTSSSAESTEHGERTP 490
Query: 250 LQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASA 309
L P + E+ E + S + E + K L+ ++ P++ + +A
Sbjct: 491 LANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVE-PTENRETTA 549
Query: 310 SGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPS----KFPFPTKESQQSNFGTGEQKRY 365
+ E T TP EP+ + PF +++ S+ E
Sbjct: 550 N-----------EKT-----------TPSPAEPTENGQRTPFANEKTTSSSAEPTEHGER 587
Query: 366 NPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSR 425
P N S + ++ + +++E + TP +N + + +E +N +
Sbjct: 588 TPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQ 647
Query: 426 DDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHK 485
++ + SSS +E E + + N +P P P N+ + N +P
Sbjct: 648 RTPFANEKTTSSSAEPTEHEERTPLANEN-----TTPSPAEPTENRERTANENTTPSPAG 702
Query: 486 VSPASSVDSNIPSS--QGYKKEGREQGTGNSYTDTSG--PKETSSATPGRDSKTIQKGSE 541
+ + +N ++ E RE+ T N T +S P E TP + KT +E
Sbjct: 703 PTENREMTANEKTTLFPAEPTENRER-TANEKTTSSPAEPTENGQRTPFANEKTTSSSAE 761
Query: 542 SGRGRQKSPAQSDSTT---------QRRTVGKK------QPKKAEKAAAEE--------- 577
+++P +++TT + RT +K +P + + A E
Sbjct: 762 PTEHGERTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQP 821
Query: 578 ----PRGGLKIESETP-----VDLASSMPSSRHKAATKGS-------RKPNIKKESKSSP 621
R L E TP + P + K + + R P + + SSP
Sbjct: 822 TENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSP 881
Query: 622 RPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSV 681
E ++ + K++Q E E S+++ + ++ ++ + T + P+
Sbjct: 882 AEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEP 941
Query: 682 EEED 685
E +
Sbjct: 942 TEHE 945
Score = 38.5 bits (88), Expect = 0.038
Identities = 123/642 (19%), Positives = 233/642 (36%), Gaps = 130/642 (20%)
Query: 78 PKPTVP-------PSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSG 130
P P P P A+EK+ P+ E G K TP +TS S + +
Sbjct: 816 PSPAQPTENGDRTPLANEKTTPSLAEPTENG-----KRTPFANEKTTSSSAEPTE----- 865
Query: 131 HSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSL 190
++RT + + T+S + + N +++ K Q +E +++R S+ +
Sbjct: 866 -HAERTPLANENTTSSPAEPTE----NRERTANEKTTQFPAEPTENRESTANEKTTPFPA 920
Query: 191 NSSHSRSHGNDHHSK-------EHQRSKSPRDPDANWDSPSR--------------VPFS 229
+ +R + ++ EH+ +P D N +P R V +
Sbjct: 921 EPTENREWTANENTTLSPAEPTEHEEM-TPLMVDENLQAPFRQGSCAERPKDICATVAST 979
Query: 230 SGQHSTQS---FPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTE 286
+G S+ + S MS S + ++ + + P +SS Y + +++E
Sbjct: 980 TGSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIP-VSSTAYETIRFSTAVSE 1038
Query: 287 LKPSSKAHL-------------TKLKIPSQPLDASASG--DVSCVDEILKEMTHSWPPPL 331
+S L T + S P AS SG + + + + E T +
Sbjct: 1039 PVTASILALESTLAFTTVSNTTTSSTVTSVPTTASTSGSKNTTACEATMSETT------I 1092
Query: 332 TAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDD-LKLSSSE 390
AI T S T+ S + P+ T+ S ++ K++ L + +S
Sbjct: 1093 AAITASEDTTVS-----TQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITST 1147
Query: 391 DSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSD 450
S KTM +T + S S S +GSE + S ++S +++
Sbjct: 1148 PSTAPNTASKTM--TTASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAIS 1205
Query: 451 SEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQG 510
++A+ + ++P PP +PA + +++P++ G
Sbjct: 1206 TKASGTTVESAPSTAPP-------------------TPAETTTASVPTTTS------TTG 1240
Query: 511 TGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKA 570
+ N+ T T+ +S T GSE+ R + + + T T G + +
Sbjct: 1241 SENTGHHTVSSVPTTVFATASESST---GSETTRASTSATEVTTAMTTAMTTGSETAVVS 1297
Query: 571 EKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKY 630
KA + G A+ MP+ K + +S TA Y
Sbjct: 1298 TKAPVTTTQSGF--------STATVMPA----------------KTTTASVSTTASTTLY 1333
Query: 631 KSTSKSSQKSREIIETDTSSSDSDESESLP-PSSQTPKYPES 671
++T S KS +++ +S + S+ + P++ K PE+
Sbjct: 1334 QNTIDSVAKSVPTMDSTIASKSTTLSKIVSVPTAVFIKAPET 1375
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 75.1 bits (183), Expect = 4e-13
Identities = 125/631 (19%), Positives = 213/631 (33%), Gaps = 103/631 (16%)
Query: 378 SMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADN-SRDDSSSHSGSES 436
S+L D + ED DG++D DK P E +E + R + + E
Sbjct: 108 SLLSDIISSEDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEK 167
Query: 437 SSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNI 496
G + E + +A + E T L K + S +
Sbjct: 168 EKGKEKVREKEKPEKKATHKEKIEKKEKPETKT--------LAKEQKKAKTAEKSEEKTK 219
Query: 497 PSSQGYKKEGREQGTG---NSYTDTSGPKETSSATPGRDSKTIQKG-------------- 539
+G K+E +Q S PKE SK QK
Sbjct: 220 KEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVH 279
Query: 540 -----------------SESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGL 582
++ R SPA + +++ KK + +K E+ +
Sbjct: 280 GDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIK--K 337
Query: 583 KIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSRE 642
K E ET +D+ P G + K + + A+K + K SK ++K E
Sbjct: 338 KSEKETAIDVEKKEP---------GKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAE 388
Query: 643 IIETDTSSSDSDESESLPPSSQTPKY--PESNRTPVKPSSVEEEDSFFRQRMFSPMEEKE 700
+ + + E P S ++ P + K +EE + P +++E
Sbjct: 389 VEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEE 448
Query: 701 LLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEK-HTREAQKQASEK 759
+ E + R K L K+ EP KG+++ VP +E + + EK
Sbjct: 449 KTTKTVEQEIRKEKSGKTSSIL---------KDKEPIKGKEEKVPASLKEKEPETKKDEK 499
Query: 760 VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAK-----------E 808
+S GK + + +KP+ + K A S + KQ K E
Sbjct: 500 MSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEE 559
Query: 809 KDL-------LPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSST 861
K L + A P P+K K EH R+ ++ K + E + S K +
Sbjct: 560 KVLKQVKAVTIEKTAKPKPTK--KAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEI 617
Query: 862 SKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQE 921
S++ E K + K ++E+ S+ + KP R +D +
Sbjct: 618 SEK---ESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVED--------VPA 666
Query: 922 AKKLKHNADALSDRFEKAVYYLDAVVSFIEC 952
+KK K + +S +K + +SF +C
Sbjct: 667 SKKAKEGTEDVSPTKQK------SPISFFQC 691
Score = 47.4 bits (111), Expect = 8e-05
Identities = 63/293 (21%), Positives = 109/293 (37%), Gaps = 63/293 (21%)
Query: 732 KETEPPKGEKKNVPE-----KHTREAQKQASEKVSNKGK------------RKHKNEDDN 774
KE K EK+ PE K T + +++ EKV K K +K K E
Sbjct: 141 KEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKT 200
Query: 775 RASESKKPKTEDKNSAGHK---PSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSR 831
A E KK KT +K+ K +E KQ+AAK K++ +P+ P +D + S+
Sbjct: 201 LAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSK 260
Query: 832 KRTISQSSSLK-----------------------SSSNSNKETSGSSKNSSSTSKQKKTE 868
Q + + + +++ T S ++KK E
Sbjct: 261 HEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAE 320
Query: 869 GKTSSSSK-----EVKEKAPSSSS-NCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEA 922
K +S +K ++K+K+ ++ + P S + T + D +++
Sbjct: 321 KKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDS 380
Query: 923 KKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVD 975
KK K A+ + +K EK+ + +KSP +S D
Sbjct: 381 KKTKKPAEVEQPKGKKQ--------------EKKEKHVEPAKSPKKEHSVPSD 419
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 74.3 bits (181), Expect = 6e-13
Identities = 112/524 (21%), Positives = 183/524 (34%), Gaps = 75/524 (14%)
Query: 282 NSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTE 341
N+ +E K HL + P+ PL++S S + S V +
Sbjct: 24 NNESEDSEEWKGHLAQA--PTPPLESSESSEGSKVSS----------------EEQANED 65
Query: 342 PSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSML----KDDLKLSSSEDSDGEQD 397
PS +S QS G G + + G + KDD + S +D+ G+ D
Sbjct: 66 PS-------DSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDD 118
Query: 398 CDKTMPRSTPGSNSEPSHHNSE-GADNSRDDSSSHSGSESSSGSDSESESSSSDSEA-NE 455
S PG NS G+D DD+ S + G DS +++S E NE
Sbjct: 119 -------SGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNE 171
Query: 456 PSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSY 515
+ PE ++W+ + + S + + Q E GNS
Sbjct: 172 DRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSR 231
Query: 516 TDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAA 575
+++G K S G +S+ G + P++ R + + + +
Sbjct: 232 MNSAGMKSKES---GENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTM 288
Query: 576 EEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSK 635
EE + E+ D S P K ++ K N+ +E + + + ++
Sbjct: 289 EEVKSD-STENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLS 347
Query: 636 SSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSP 695
S + S E E S S D + P +S +S+ S EE+ S S
Sbjct: 348 SQENSSESQEEVVSESRGDNPD--PTTSYVEDQEDSD-------SSEEDSSHTLSHSKSE 398
Query: 696 MEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQ 755
E++ S SE LN P P E + + H+ A+ Q
Sbjct: 399 SREEQADSESSE-----------SLNFSEESPESP----EDENSSSQEGLQSHSSSAESQ 443
Query: 756 ASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRE 799
+ E H EDD+ + +S + K ED NS K SS +
Sbjct: 444 SEES--------HSEEDDSDSQDSSRSK-EDSNSTESKSSSEED 478
Score = 63.5 bits (153), Expect = 1e-09
Identities = 91/408 (22%), Positives = 147/408 (36%), Gaps = 65/408 (15%)
Query: 143 GTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSS-------PGKPQAVSSLNSSHS 195
G + G D + + S +GQ ++ + S S KP+ S S S
Sbjct: 130 GNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESES 189
Query: 196 RSH---GNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQK 252
H G H D D P + G S+ NS
Sbjct: 190 EEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGN-----------SRMNSA--- 235
Query: 253 PTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGD 312
G +S E +SE ++Q G S PS K K +I S+ D S D
Sbjct: 236 ---------GMKSKESGENSEQANTQDSGGSQLLEHPSRKI-FRKSRI-SEEDDRSELDD 284
Query: 313 VSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSN 372
+ ++E+ + T + T + P + ++E + N E S+ +
Sbjct: 285 NNTMEEVKSDSTENSNSRDTGLSQPRRDSKGD----SQEDSKENLSQEE------SQNVD 334
Query: 373 GHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSH---HNSEGADNSRDDSS 429
G S+S + LSS E+S Q+ + + G N +P+ + E +D+S +DS
Sbjct: 335 GPSSES--SQEANLSSQENSSESQE---EVVSESRGDNPDPTTSYVEDQEDSDSSEEDS- 388
Query: 430 SHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPA 489
S + S S SES +DSE++E + PE P L S +
Sbjct: 389 ----SHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQ-------SHS 437
Query: 490 SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQ 537
SS +S S + + Q + S D++ + SS+ K I+
Sbjct: 438 SSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIE 485
Score = 50.1 bits (118), Expect = 1e-05
Identities = 107/497 (21%), Positives = 182/497 (36%), Gaps = 84/497 (16%)
Query: 422 DNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKV 481
+N +DS G + + + S SS+ + A+ +P ++ Q + L
Sbjct: 24 NNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSEEQANEDP----SDSTQSEEGLGSD 79
Query: 482 NPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSE 541
+ + + S G K+ E +G+ DT G ++ R E
Sbjct: 80 DHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGD---DTFGDDDSGPGPKDRQ--------E 128
Query: 542 SGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRH 601
G R S SD T Q Q + + + E R ++++E VD
Sbjct: 129 GGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESR---ELDNEDRVDS--------- 176
Query: 602 KAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSR-EIIETDTSSSDSDESESLP 660
K E S + + ++ + + S + E D SD+ ES+
Sbjct: 177 ------------KPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIR 224
Query: 661 P----SSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLI- 715
S +S + +DS Q + P + S +SE DDR L
Sbjct: 225 SERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDD 284
Query: 716 ------VKIDL--NLLTRIPG--KPYKETEPPKGE--KKNVPEKHTREAQKQASEKVSNK 763
VK D N +R G +P ++++ E K+N+ ++ ++ +SE
Sbjct: 285 NNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEA 344
Query: 764 GKRKHKNEDDNR---ASESK----KPKT------EDKNSA--------GHKPSSNRESSK 802
+N +++ SES+ P T ED +S+ H S +RE
Sbjct: 345 NLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQA 404
Query: 803 QSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTI-SQSSSLKSSSN-SNKETSGSSKNSSS 860
S + E L S P + P+ E+ S + + S SSS +S S S+ E S SS
Sbjct: 405 DSESSES-LNFSEESP---ESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSS 460
Query: 861 TSKQKKTEGKTSSSSKE 877
SK+ ++ SSS+E
Sbjct: 461 RSKEDSNSTESKSSSEE 477
Score = 49.3 bits (116), Expect = 2e-05
Identities = 82/413 (19%), Positives = 155/413 (37%), Gaps = 54/413 (13%)
Query: 54 SMLGNYDEMKDFI--GDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGG-----SHQSS 106
S LG+ ++ D I + S P+ + T S + + + GG S
Sbjct: 132 SRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSKPEGGDSTQESESEE 191
Query: 107 KWTPVGPAPSTSQ---SQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSS 163
W G +S S+ G+QS S +S NS+G + SG +S
Sbjct: 192 HWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGMKS-----KESGENS 246
Query: 164 RKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSP 223
+ S S+ K S ++ RS +D+++ E +S S + ++
Sbjct: 247 EQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL 306
Query: 224 SRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNS 283
S+ S S + +L + + + P++ + S E LSS+ SS+S
Sbjct: 307 SQPRRDSKGDSQEDSKENLSQEESQNVDGPSS-------ESSQEANLSSQENSSESQEEV 359
Query: 284 MTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPS 343
++E + + T + D+S ++ ++HS K+E
Sbjct: 360 VSESRGDNPDPTTSYVEDQEDSDSSE-------EDSSHTLSHS------------KSESR 400
Query: 344 KFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMP 403
+ ++ S+ NF E+ +P ++ Q S SE+S E+D
Sbjct: 401 EEQADSESSESLNF--SEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEED------ 452
Query: 404 RSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEP 456
S+S+ S + E ++++ SSS + + + ES + D+ N+P
Sbjct: 453 ----DSDSQDSSRSKEDSNSTESKSSSEEDGQLKN-IEIESRKLTVDAYHNKP 500
Score = 43.1 bits (100), Expect = 0.002
Identities = 45/189 (23%), Positives = 70/189 (37%), Gaps = 27/189 (14%)
Query: 3 REDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEM 62
R+ + + +E +QE Q D P +S+E LSS+ S + +
Sbjct: 311 RDSKGDSQEDSKENLSQEESQNVDG----------PSSESSQEANLSSQENSSESQEEVV 360
Query: 63 KDFIGDRSIPKLVAIPKPTVPPSADEKSNPNFF--------EQRHGGSHQSSKWTPVGPA 114
+ GD P + S++E S+ EQ S +S ++ P
Sbjct: 361 SESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPE 420
Query: 115 PSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHS 174
++ GLQS SSS + S + H E ++S SSR K S S
Sbjct: 421 SPEDENSSSQEGLQSH---------SSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTES 471
Query: 175 KSRSSSPGK 183
KS S G+
Sbjct: 472 KSSSEEDGQ 480
Score = 32.7 bits (73), Expect = 2.1
Identities = 32/156 (20%), Positives = 67/156 (42%), Gaps = 6/156 (3%)
Query: 723 LTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKP 782
+TR +++E KG P ++ KVS++ + NED + +++S++
Sbjct: 19 VTRYQNNESEDSEEWKGHLAQAPTPPLESSESSEGSKVSSE---EQANEDPSDSTQSEEG 75
Query: 783 KTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLK 842
D + ++ + S +KD +G D + G + R +S L
Sbjct: 76 LGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLG 135
Query: 843 SSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV 878
S +S+ +T +S+ S+ + + T+S S+E+
Sbjct: 136 SDEDSD-DTIQASEESAPQGQDSAQD--TTSESREL 168
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 74.3 bits (181), Expect = 6e-13
Identities = 191/952 (20%), Positives = 345/952 (36%), Gaps = 159/952 (16%)
Query: 80 PTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGH-SSQRTSA 138
PT A EKS N + + S GP +++K +S SS +
Sbjct: 561 PTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADS 620
Query: 139 GSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHS---KSRSSSPGKPQAVSSLNSSHS 195
+ ++ Q + + +K S + + +P K +S S
Sbjct: 621 EEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP 680
Query: 196 RSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSM-----L 250
G E S D + + + + + GQ +S L K+ S+ L
Sbjct: 681 AVAGGTQRPAEDSSSSEESDSE---EEKTGLAVTVGQ--AKSVGKGLQVKAASVPVKGSL 735
Query: 251 QKPTAYVRP---------MDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIP 301
+ TA V P + ++ + + S E S+ S ++K S K K P
Sbjct: 736 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN-P 794
Query: 302 SQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSN-FGTG 360
+ SA G +S +++ TA + PSK P + Q S G
Sbjct: 795 AAARAPSAKGTISAPGKVV-----------TAAAQAKQRSPSKVKPPVRNPQNSTVLARG 843
Query: 361 EQKRYNPSKT-SNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE------- 412
+ K + Q+++ ++D SS E+SD E++ + T+ + P +
Sbjct: 844 PASVPSVGKAVATAAQAQTGPEEDSG-SSEEESDSEEEAE-TLAQVKPSGKTHQIRAALA 901
Query: 413 PSHHNS-EGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNK 471
P+ + +GA + + S +++ DS S S SDS+ P+ S + PP
Sbjct: 902 PAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP--- 958
Query: 472 WQLDNWLNKVNPHKVSPA--SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKE----TS 525
L V+P++ SPA ++ + ++ +K + T S + S ++ T
Sbjct: 959 ------LIFVDPNR-SPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ 1011
Query: 526 SATPGRDSKTIQKGSESGRGRQKSP---AQSDSTTQRRTVGKKQPKKAEKAAAEEP---- 578
TPG + + + R K+ A S + R + GKKQ A + + + P
Sbjct: 1012 CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLP 1071
Query: 579 --RGGLKI----ESETPVDLASSMPSSRHKAAT---------------KGS---RKPNIK 614
+ LK+ SE +A + PSS +A KG+ RKP +
Sbjct: 1072 LTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLP 1131
Query: 615 KESKSSPRPTAEKKKYKSTSKSSQKSRE-----------------------IIETDTSSS 651
+ +++ P + S+ SS + + ET SS
Sbjct: 1132 EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESS 1191
Query: 652 DSD---ESESL----------PPSSQTPKY-PESNRTPVKPSSVEEEDSFFRQRMFSPME 697
+ D S+SL P +SQ K P+ + +P S++ +D ++ P +
Sbjct: 1192 EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQ 1251
Query: 698 EKELLSP----------LSEPDDRYPL---------IVKIDLNLLTRIPGKPY--KETEP 736
+LSP + R P + + N+ + G+P+ E +
Sbjct: 1252 AAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQV 1311
Query: 737 PKGEKKNVPEKHTREAQK--QASEKVSNKG--KRKHKNEDDNRASESKKPKTEDKNSAGH 792
K + E +E +K +++ S KG RK K D A+ + + K + K AG
Sbjct: 1312 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1371
Query: 793 KPSSNRESSKQSA-AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKET 851
++ K S +K K +G V K K GS+ L+ + +
Sbjct: 1372 GGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVE-- 1429
Query: 852 SGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRR 903
G N S ++KK++ + K+ K+K +S +P+ K ++
Sbjct: 1430 GGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKK 1481
Score = 60.8 bits (146), Expect = 7e-09
Identities = 116/529 (21%), Positives = 200/529 (37%), Gaps = 112/529 (21%)
Query: 408 GSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESES---SSSDSEANEPSQSASPEP 464
G+ ++P ++ AD+S +D+SS S G S + +SS S P++ A+P P
Sbjct: 183 GAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAP 242
Query: 465 EPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKET 524
+ V P A +P ++ KK
Sbjct: 243 -----------GKVGDVTPQVKGGA------LPPAKRAKK-------------------- 265
Query: 525 SSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKI 584
P +S++ ++GSES +++PA + R+ K K + AA P G
Sbjct: 266 ----PEEESESSEEGSES---EEEAPAGT------RSQVKASEKILQVRAASAPAKG--- 309
Query: 585 ESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREII 644
TP A+ P + A ++ +++S+SS +++ ++ +K+ +++
Sbjct: 310 ---TPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASG 366
Query: 645 ETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSV--EEEDSFFRQRMFSPMEEKELL 702
+T + S ++ P P P V + EEDS Q + +E
Sbjct: 367 KTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS---QSSSEESDSEEEA 423
Query: 703 SPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSN 762
++P + P + R P KE+ P KG P K T A Q
Sbjct: 424 PAQAKPSGKAPQV---------RAASAPAKES-PRKGAAPAPPRK-TGPAAAQV-----Q 467
Query: 763 KGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVP-- 820
GK++ + + S+S + N+A KP K ++ L AGPVP
Sbjct: 468 VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPG 527
Query: 821 ---SKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGS--------------SKNSSSTSK 863
P + G + S+SSS +SS +S+ E + +K +SS +K
Sbjct: 528 KVGPATPSAQVGKWEED-SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAK 586
Query: 864 -----------QKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKP 901
Q K E K +S+ +E + S+ S P+A T +KP
Sbjct: 587 GPPQKAGPVAVQVKAE-KPMDNSESSEESSDSADSEEAPAAMTAAQAKP 634
Score = 54.3 bits (129), Expect = 7e-07
Identities = 176/864 (20%), Positives = 302/864 (34%), Gaps = 176/864 (20%)
Query: 112 GPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKG---- 167
GPA + +Q+ KR QS + + + SG+ + + S +KG
Sbjct: 395 GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 168 ------------QHGSEHSKSRSSSPGKP---QAVSSLNSSHSRSHGNDHHSKEHQRSKS 212
Q G + SRSSS +A++++N++ + G KS
Sbjct: 455 PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLG-----------KS 503
Query: 213 PRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSMLQKPTAYVRPMDGQESMEPKLSS 272
P+ A+ + P G PP + + P+A V G+ + + SS
Sbjct: 504 PQVKPAS--TMGMGPLGKGAGPV---PPGKVGPAT-----PSAQV----GKWEEDSESSS 549
Query: 273 EHYSSQSHGNSMTELKPSSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLT 332
E S S G T + P+ + L + + ++P + A G PP
Sbjct: 550 EESSDSSDGEVPTAVAPAQEKSLGNI-LQAKPTSSPAKG-----------------PPQK 591
Query: 333 AIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDS 392
A + + K P ES + + + + + + T+ + K LK+ +
Sbjct: 592 AGPVAVQVKAEK-PMDNSESSEESSDSADSEEAPAAMTA------AQAKPALKIPQT--- 641
Query: 393 DGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSE 452
K P+ T + S G R ++ S + SS ++ + DS
Sbjct: 642 -------KACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSS 694
Query: 453 ANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSN--IPSSQGYKKEGREQG 510
++E S S + T V A SV + ++ K QG
Sbjct: 695 SSEESDSEEEKTGLAVT----------------VGQAKSVGKGLQVKAASVPVKGSLGQG 738
Query: 511 TGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKA 570
T +GP T Q+ SES S + S Q +T KK KA
Sbjct: 739 TAPVLPGKTGPTVTQVKAEK------QEDSESSEEESDSEEAAASPAQVKTSVKKTQAKA 792
Query: 571 EKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS-RKPNIKKESKSSPRPTAEKKK 629
AAA P I + V A++ R + K R P P K
Sbjct: 793 NPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGK 852
Query: 630 YKSTSKSSQKSREIIETDTSSSDSDESE--------------------SLPPSSQTPKYP 669
+T+ +Q E E SS + +SE +L P+ ++P+
Sbjct: 853 AVATAAQAQTGPE--EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKG 910
Query: 670 ESNRTPVK--PSSVE---EEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLT 724
+ P K PS+ + ++DS + E + ++ P ++ +D N
Sbjct: 911 AAPTPPGKTGPSAAQAGKQDDSGSSSE--ESDSDGEAPAAVTSAQVIKPPLIFVDPN--- 965
Query: 725 RIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASE------ 778
R P P P + + + P K +ASE + + ++ED A++
Sbjct: 966 RSPAGP--AATPAQAQAASTPRK------ARASESTARSSSSESEDEDVIPATQCLTPGI 1017
Query: 779 --------SKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKT---E 827
+ P+ K S SS++ESS+ S K+++ PA V K+P +
Sbjct: 1018 RTNVVTMPTAHPRIAPKASMA-GASSSKESSRISDGKKQE---GPATQVSKKNPASLPLT 1073
Query: 828 HGSRKRTISQSSSLKSSSNSNKETSG--------SSKNSSSTSKQKKTEGKTSSSS-KEV 878
+ K ++S + + +SG + + STS Q K K EV
Sbjct: 1074 QAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEV 1133
Query: 879 KE--KAPSSSSNCPPSAPTLDSSK 900
++ KAP SS + S+ + S+
Sbjct: 1134 QQATKAPESSDDSEDSSDSSSGSE 1157
Score = 52.8 bits (125), Expect = 2e-06
Identities = 95/422 (22%), Positives = 145/422 (34%), Gaps = 86/422 (20%)
Query: 537 QKGSESGRGRQKSPAQSDSTTQRRTVGKKQP-------KKAEKAAAEEPRGGLKIESETP 589
Q+ SE GR R+ A+ D+ Q + P ++ E+A AE + ++ S
Sbjct: 54 QQTSELGRKRK---AEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNS 110
Query: 590 VDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTS-KSSQKSREIIETDT 648
L + +PSS + A + K K S P P K S KS +KS E T
Sbjct: 111 SVLGADLPSSMKEKAKAETEKAG--KTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
Query: 649 SSSDSDESESLPPSSQTPK---------------------------YPESNRTPVKPSSV 681
S+++E S+P K P VK SSV
Sbjct: 169 LVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSV 228
Query: 682 EEEDSFFRQ------------------------RMFSPMEEKELLSPLSEPDDRYPLIVK 717
++S R+ R P EE E SE ++ P +
Sbjct: 229 STKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTR 288
Query: 718 IDLN-----LLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNED 772
+ L R P K T P KG P K A + + K + +
Sbjct: 289 SQVKASEKILQVRAASAPAKGT-PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESS 347
Query: 773 DNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKE---KDLLPSPAGPVPSKDPKTEHG 829
D SE + P + A +++ + + AKE K P+P G K + G
Sbjct: 348 D---SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAG 404
Query: 830 SRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNC 889
R+ SQSSS E S S + + + +K + ++S KE ++
Sbjct: 405 KREED-SQSSS---------EESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 454
Query: 890 PP 891
PP
Sbjct: 455 PP 456
Score = 52.0 bits (123), Expect = 3e-06
Identities = 142/757 (18%), Positives = 266/757 (35%), Gaps = 128/757 (16%)
Query: 67 GDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSG 126
G S+P + + + E+ ++ V P+ T Q + +
Sbjct: 843 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR---AA 899
Query: 127 LQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQA 186
L S R A + + ++SGSSS + G + S+ KP
Sbjct: 900 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 959
Query: 187 VSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQH-----STQSFPPS 241
+ ++ + S + G + Q + +PR A+ +S +R S + +TQ P
Sbjct: 960 IF-VDPNRSPA-GPAATPAQAQAASTPRKARAS-ESTARSSSSESEDEDVIPATQCLTPG 1016
Query: 242 LMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSS--KAHLTKLK 299
+ + +M PTA+ R + PK S SS + +++ K ++K
Sbjct: 1017 IRTNVVTM---PTAHPR-------IAPKASMAGASSSKESSRISDGKKQEGPATQVSKKN 1066
Query: 300 IPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT 359
S PL +A ++L + PP+ +T+PS +
Sbjct: 1067 PASLPLTQAAL-------KVLAQKASEAQPPVA------RTQPSS---------GVDSAV 1104
Query: 360 GEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSE 419
G +P TS + + L+ + + + D + S S SE +
Sbjct: 1105 GTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQ 1164
Query: 420 GADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASP---EPEPPPTNKWQLDN 476
GA ++ + S +E+ E+ + SS+ + PSQS P P N +
Sbjct: 1165 GAKSAHTLGPTPSRTETLV---EETAAESSEDDVVAPSQSLLSGYMTPGLTPAN-----S 1216
Query: 477 WLNKVNPHKVSPASSVDSNIPSSQGY--KKEGREQGTGNSYTDTSGPKETSSATPGRDSK 534
+K P K+ + SV S + + K+E + Q + +G KE +S T + S+
Sbjct: 1217 QASKATP-KLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSR 1275
Query: 535 TIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLAS 594
+KG+ + Q S S + +G+ P + A +K+ +E
Sbjct: 1276 KPKKGAGNP---QASTLALQSNITQCLLGQPWPLNEAQVQASV----VKVLTELLEQERK 1328
Query: 595 SMPSSRHKAATKG--SRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSD 652
+ + +++ KG SRK + + ++ P ++KKK + + S
Sbjct: 1329 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS---------- 1378
Query: 653 SDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRY 712
PE T K + ++ S ++EK+ L
Sbjct: 1379 ----------------PEKTSTTSKGKAKRDKAS-------GDVKEKKGKGSL------- 1408
Query: 713 PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKG-KRKHKNE 771
G + EP + +K + + S+K K KRK E
Sbjct: 1409 ---------------GSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE 1453
Query: 772 DDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKE 808
+ ++KK T+D S PS ++ K+ A++
Sbjct: 1454 KKEKKKKAKKASTKDSES----PSQKKKKKKKKTAEQ 1486
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 74.3 bits (181), Expect = 6e-13
Identities = 195/953 (20%), Positives = 343/953 (35%), Gaps = 158/953 (16%)
Query: 80 PTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGH-SSQRTSA 138
PT A EKS N + + S GP +++K +S SS +
Sbjct: 484 PTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADS 543
Query: 139 GSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHS---KSRSSSPGKPQAVSSLNSSHS 195
+ ++ Q + + +K S + + +P K +S S
Sbjct: 544 EEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSP 603
Query: 196 RSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQHSTQSFPPSLMSKSNSM-----L 250
G E S D + + + + + GQ +S L K+ S+ L
Sbjct: 604 AVAGGTQRPAEDSSSSEESDSE---EEKTGLAVTVGQ--AKSVGKGLQVKAASVPVKGSL 658
Query: 251 QKPTAYVRP---------MDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIP 301
+ TA V P + ++ + + S E S+ S ++K S K K P
Sbjct: 659 GQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKAN-P 717
Query: 302 SQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSN-FGTG 360
+ SA G +S +++ TA + PSK P + Q S G
Sbjct: 718 AAARAPSAKGTISAPGKVV-----------TAAAQAKQRSPSKVKPPVRNPQNSTVLARG 766
Query: 361 EQKRYNPSKT-SNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSE------- 412
+ K + Q+++ ++D SS E+SD E++ + T+ + P +
Sbjct: 767 PASVPSVGKAVATAAQAQTGPEEDSG-SSEEESDSEEEAE-TLAQVKPSGKTHQIRAALA 824
Query: 413 PSHHNS-EGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNK 471
P+ + +GA + + S +++ DS S S SDS+ P+ S + PP
Sbjct: 825 PAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPP--- 881
Query: 472 WQLDNWLNKVNPHKVSPA--SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKE----TS 525
L V+P++ SPA ++ + ++ +K + T S + S ++ T
Sbjct: 882 ------LIFVDPNR-SPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQ 934
Query: 526 SATPGRDSKTIQKGSESGRGRQKSP---AQSDSTTQRRTVGKKQPKKAEKAAAEEP---- 578
TPG + + + R K+ A S + R + GKKQ A + + + P
Sbjct: 935 CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLP 994
Query: 579 --RGGLKI----ESETPVDLASSMPSSRHKAAT---------------KGS---RKPNIK 614
+ LK+ SE +A + PSS +A KG+ RKP +
Sbjct: 995 LTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLP 1054
Query: 615 KESKSSPRPTAEKKKYKSTSKSSQKSRE-----------------------IIETDTSSS 651
+ +++ P + S+ SS + + ET SS
Sbjct: 1055 EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESS 1114
Query: 652 DSD---ESESL----------PPSSQTPKY-PESNRTPVKPSSVEEEDSFFRQRMFSPME 697
+ D S+SL P +SQ K P+ + +P S++ +D ++ P +
Sbjct: 1115 EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQ 1174
Query: 698 EKELLSP----------LSEPDDRYPL---------IVKIDLNLLTRIPGKPY--KETEP 736
+LSP + R P + + N+ + G+P+ E +
Sbjct: 1175 AAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQV 1234
Query: 737 PKGEKKNVPEKHTREAQK--QASEKVSNKG--KRKHKNEDDNRASESKKPKTEDKNSAGH 792
K + E +E +K +++ S KG RK K D A+ + + K + K AG
Sbjct: 1235 QASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1294
Query: 793 KPSSNRESSKQSA-AKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKET 851
++ K S +K K +G V K K GS+ L+ + E
Sbjct: 1295 GGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGT-VEG 1353
Query: 852 SGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRT 904
S S K+K + K KE K+KA +S+ S K ++T
Sbjct: 1354 GDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKT 1406
Score = 65.1 bits (157), Expect = 4e-10
Identities = 168/883 (19%), Positives = 314/883 (35%), Gaps = 131/883 (14%)
Query: 112 GPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKG---- 167
GPA + +Q+ KR QS + + + SG+ + + S +KG
Sbjct: 318 GPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPA 377
Query: 168 ------------QHGSEHSKSRSS---SPGKPQAVSSLNSSHSRSHGNDHHSKEHQR--- 209
Q G + SRSS S +A++++N++ + G K
Sbjct: 378 PPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGM 437
Query: 210 -------------SKSPRDPDA---NWDSPSR------VPFSSGQHSTQSFPPSLMSKSN 247
P P A W+ S S G+ T P S N
Sbjct: 438 GPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGN 497
Query: 248 SMLQKPTA------------------YVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKP 289
+ KPT+ +PMD ES E SS+ S+ +MT +
Sbjct: 498 ILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEE--SSDSADSEEAPAAMTAAQA 555
Query: 290 SSKAHLTKLKIPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPS---KFP 346
+ + K + + +AS V+ V + P +P + P+
Sbjct: 556 KPALKIPQTKACPKKTNTTASAKVAPV-----RVGTQAPRKAGTATSPAGSSPAVAGGTQ 610
Query: 347 FPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGE--QDCDKTMPR 404
P ++S S E+++ + T Q+KS+ K ++S G Q +P
Sbjct: 611 RPAEDSSSSEESDSEEEKTGLAVTVG--QAKSVGKGLQVKAASVPVKGSLGQGTAPVLPG 668
Query: 405 STPGSNSEPSHHNSEGADNSRDDSSSHSGSESSS---GSDSESESSSSDSEANEPSQSAS 461
T + ++ E +++S ++S S + S + S ++++ ++ + A PS +
Sbjct: 669 KTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGT 728
Query: 462 -PEPEPPPTNKWQL-DNWLNKVNPHKVSPASSV-----DSNIPS------SQGYKKEGRE 508
P T Q +KV P +P +S +++PS + + G E
Sbjct: 729 ISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPE 788
Query: 509 QGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPK 568
+ +G+S ++ +E + + S + + ++SP + + T GK P
Sbjct: 789 EDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPT---PPGKTGPS 845
Query: 569 KAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKK 628
A+ A ++ G ES++ + +++ S+ + + P I + SP A
Sbjct: 846 AAQ-AGKQDDSGSSSEESDSDGEAPAAVTSA------QVIKPPLIFVDPNRSPAGPAATP 898
Query: 629 KYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQ--TP-------KYPESNRTPVKPS 679
+ + +K+R T SSS E E + P++Q TP P ++ +
Sbjct: 899 AQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKA 958
Query: 680 SVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGK------PYKE 733
S+ S S +++E P ++ + P + + L + K P
Sbjct: 959 SMAGASSSKESSRISDGKKQE--GPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVAR 1016
Query: 734 TEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHK 793
T+P G V Q + + RK K + +A+++ + + ++S+
Sbjct: 1017 TQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS 1076
Query: 794 PSSNRESSKQSAAKEKDLLPSPAGPVPSK-----DPKTEHGSRKRTISQSSSLKSSSNSN 848
S + AK L GP PS+ + S ++ S SL S +
Sbjct: 1077 SGSEEDGEGPQGAKSAHTL----GPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTP 1132
Query: 849 KETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPP 891
T +S+ S +T K + S SS + P P
Sbjct: 1133 GLTPANSQASKAT---PKLDSSPSVSSTLAAKDDPDGKQEAKP 1172
Score = 60.5 bits (145), Expect = 9e-09
Identities = 116/534 (21%), Positives = 201/534 (37%), Gaps = 97/534 (18%)
Query: 424 SRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNP 483
+ +D++ + S S SESS + EA +++A P TN
Sbjct: 65 AEEDAALQAKKTRVSDPISTSESSEEEEEAE--AETAKATPRLASTN------------- 109
Query: 484 HKVSPASSVDSNIPSSQGYKKEGREQ---GTGNSYTD----------TSGPKETSSATPG 530
+S + +++PSS K + + TGNS SG SA P
Sbjct: 110 -----SSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPS 164
Query: 531 RD----SKTIQKGSESGRGRQKSP-----AQSDSTTQRRTVGKKQPKKAEKAAAE--EPR 579
+ S+T ++GS G P Q+DS+++ + + KA+ + + R
Sbjct: 165 ANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVR 224
Query: 580 GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQK 639
TP A+ P + A ++ +++S+SS +++ ++ +K+ +
Sbjct: 225 AASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQ 284
Query: 640 SREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSV--EEEDSFFRQRMFSPME 697
++ +T + S ++ P P P V + EEDS Q +
Sbjct: 285 AKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS---QSSSEESD 341
Query: 698 EKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQAS 757
+E ++P + P + R P KE+ P KG P K T A Q
Sbjct: 342 SEEEAPAQAKPSGKAPQV---------RAASAPAKES-PRKGAAPAPPRK-TGPAAAQV- 389
Query: 758 EKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAG 817
GK++ + + S+S + N+A KP K ++ L AG
Sbjct: 390 ----QVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAG 445
Query: 818 PVP-----SKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGS--------------SKNS 858
PVP P + G + S+SSS +SS +S+ E + +K +
Sbjct: 446 PVPPGKVGPATPSAQVGKWEED-SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPT 504
Query: 859 SSTSK-----------QKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKP 901
SS +K Q K E K +S+ +E + S+ S P+A T +KP
Sbjct: 505 SSPAKGPPQKAGPVAVQVKAE-KPMDNSESSEESSDSADSEEAPAAMTAAQAKP 557
Score = 54.3 bits (129), Expect = 7e-07
Identities = 87/366 (23%), Positives = 135/366 (36%), Gaps = 51/366 (13%)
Query: 537 QKGSESGRGRQKSPAQSDSTTQRRTVGKKQP-------KKAEKAAAEEPRGGLKIESETP 589
Q+ SE GR R+ A+ D+ Q + P ++ E+A AE + ++ S
Sbjct: 54 QQTSELGRKRK---AEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNS 110
Query: 590 VDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTS-KSSQKSREIIETDT 648
L + +PSS + A + K K S P P K S KS +KS E T
Sbjct: 111 SVLGADLPSSMKEKAKAETEKAG--KTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTT 168
Query: 649 SSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEP 708
S+++E S+P K P S+ + + S ++ S E
Sbjct: 169 LVSETEEEGSVPAFGAAAK-------PGMVSAGQADSS-----------SEDTSSSSDET 210
Query: 709 DDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKH 768
D KI L R P K T P KG P K A + + K +
Sbjct: 211 DVEVKASEKI---LQVRAASAPAKGT-PGKGATPAPPGKAGAVASQTKAGKPEEDSESSS 266
Query: 769 KNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKE---KDLLPSPAGPVPSKDPK 825
+ D SE + P + A +++ + + AKE K P+P G K
Sbjct: 267 EESSD---SEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAK 323
Query: 826 TEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSS 885
+ G R+ SQSSS E S S + + + +K + ++S KE
Sbjct: 324 AQAGKREED-SQSSS---------EESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKG 373
Query: 886 SSNCPP 891
++ PP
Sbjct: 374 AAPAPP 379
Score = 52.0 bits (123), Expect = 3e-06
Identities = 142/757 (18%), Positives = 266/757 (35%), Gaps = 128/757 (16%)
Query: 67 GDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRHGGSHQSSKWTPVGPAPSTSQSQKRSSG 126
G S+P + + + E+ ++ V P+ T Q + +
Sbjct: 766 GPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIR---AA 822
Query: 127 LQSGHSSQRTSAGSSSGTNSSGQRHDRESYNNSGSSSRKKGQHGSEHSKSRSSSPGKPQA 186
L S R A + + ++SGSSS + G + S+ KP
Sbjct: 823 LAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPL 882
Query: 187 VSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSRVPFSSGQH-----STQSFPPS 241
+ ++ + S + G + Q + +PR A+ +S +R S + +TQ P
Sbjct: 883 IF-VDPNRSPA-GPAATPAQAQAASTPRKARAS-ESTARSSSSESEDEDVIPATQCLTPG 939
Query: 242 LMSKSNSMLQKPTAYVRPMDGQESMEPKLSSEHYSSQSHGNSMTELKPSS--KAHLTKLK 299
+ + +M PTA+ R + PK S SS + +++ K ++K
Sbjct: 940 IRTNVVTM---PTAHPR-------IAPKASMAGASSSKESSRISDGKKQEGPATQVSKKN 989
Query: 300 IPSQPLDASASGDVSCVDEILKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGT 359
S PL +A ++L + PP+ +T+PS +
Sbjct: 990 PASLPLTQAAL-------KVLAQKASEAQPPVA------RTQPSS---------GVDSAV 1027
Query: 360 GEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSE 419
G +P TS + + L+ + + + D + S S SE +
Sbjct: 1028 GTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQ 1087
Query: 420 GADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASP---EPEPPPTNKWQLDN 476
GA ++ + S +E+ E+ + SS+ + PSQS P P N +
Sbjct: 1088 GAKSAHTLGPTPSRTETLV---EETAAESSEDDVVAPSQSLLSGYMTPGLTPAN-----S 1139
Query: 477 WLNKVNPHKVSPASSVDSNIPSSQGY--KKEGREQGTGNSYTDTSGPKETSSATPGRDSK 534
+K P K+ + SV S + + K+E + Q + +G KE +S T + S+
Sbjct: 1140 QASKATP-KLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSR 1198
Query: 535 TIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLAS 594
+KG+ + Q S S + +G+ P + A +K+ +E
Sbjct: 1199 KPKKGAGNP---QASTLALQSNITQCLLGQPWPLNEAQVQASV----VKVLTELLEQERK 1251
Query: 595 SMPSSRHKAATKG--SRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSD 652
+ + +++ KG SRK + + ++ P ++KKK + + S
Sbjct: 1252 KVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVS---------- 1301
Query: 653 SDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRY 712
PE T K + ++ S ++EK+ L
Sbjct: 1302 ----------------PEKTSTTSKGKAKRDKAS-------GDVKEKKGKGSL------- 1331
Query: 713 PLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKG-KRKHKNE 771
G + EP + +K + + S+K K KRK E
Sbjct: 1332 ---------------GSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKE 1376
Query: 772 DDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKE 808
+ ++KK T+D S PS ++ K+ A++
Sbjct: 1377 KKEKKKKAKKASTKDSES----PSQKKKKKKKKTAEQ 1409
Score = 46.2 bits (108), Expect = 2e-04
Identities = 100/555 (18%), Positives = 192/555 (34%), Gaps = 74/555 (13%)
Query: 387 SSSEDSDGEQDCDKTM---------PRSTPGSNSEPSHHNSEGADNSR---------DDS 428
SSS+++D E + + + TPG + P+ GA S+ +S
Sbjct: 205 SSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSES 264
Query: 429 SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSP 488
SS S+S + + + + A+ P K K P
Sbjct: 265 SSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKA 324
Query: 489 ASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQK 548
+ S + + E+ + P+ +++ P ++S +KG+ R+
Sbjct: 325 QAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESP--RKGAAPAPPRKT 382
Query: 549 SPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSM-PSSRHKAATKG 607
PA + ++ + + E + E + P+ + + P+S G
Sbjct: 383 GPAAAQVQVGKQEEDSRSSSE-ESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLG 441
Query: 608 SRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTP- 666
+ P+A+ K++ S+SS E + SSD + ++ P+ +
Sbjct: 442 KGAGPVPPGKVGPATPSAQVGKWEEDSESSS------EESSDSSDGEVPTAVAPAQEKSL 495
Query: 667 ---KYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLL 723
+ +P K + + + PM+ E S+ D +
Sbjct: 496 GNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA-----AM 550
Query: 724 TRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPK 783
T KP + K K + +T + K A +V + RK A + P
Sbjct: 551 TAAQAKPALKIPQTKACPK---KTNTTASAKVAPVRVGTQAPRK--------AGTATSPA 599
Query: 784 TEDKNSAG--HKPSSNRESSKQSAAKEKDL---------------LPSPAGPVPSKDPKT 826
AG +P+ + SS++S ++E+ L A VP K
Sbjct: 600 GSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLG 659
Query: 827 E------HGSRKRTISQSSSLK-SSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVK 879
+ G T++Q + K S S++E S S + ++S ++ K + KT + +
Sbjct: 660 QGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAA 719
Query: 880 EKAPSSSSNCPPSAP 894
+APS+ SAP
Sbjct: 720 ARAPSAKGTI--SAP 732
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.118 0.326
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 50,536,001
Number of Sequences: 37866
Number of extensions: 2702289
Number of successful extensions: 36758
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 443
Number of HSP's successfully gapped in prelim test: 1575
Number of HSP's that attempted gapping in prelim test: 16435
Number of HSP's gapped (non-prelim): 12075
length of query: 1163
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1050
effective length of database: 13,968,660
effective search space: 14667093000
effective search space used: 14667093000
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.