Guide to the Human Genome
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Search of human proteins with 71274111

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene
homolog A [Homo sapiens]
         (353 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene homol...   747   0.0  
gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homol...   319   2e-87
gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...   319   2e-87
gi|23308699 transcription factor MAFB [Homo sapiens]                  306   2e-83
gi|5453802 neural retina leucine zipper [Homo sapiens]                199   3e-51
gi|4505075 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...   108   9e-24
gi|4505073 v-maf musculoaponeurotic fibrosarcoma oncogene homolo...   107   2e-23
gi|49619228 v-maf musculoaponeurotic fibrosarcoma oncogene homol...   107   2e-23
gi|239048388 transcription factor MAFF isoform a [Homo sapiens]        97   3e-20
gi|239048350 transcription factor MAFF isoform a [Homo sapiens]        97   3e-20
gi|6912490 transcription factor MAFF isoform a [Homo sapiens]          97   3e-20
gi|239048390 transcription factor MAFF isoform b [Homo sapiens]        91   2e-18
gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]      75   9e-14
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    69   8e-12
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    69   8e-12
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    69   8e-12
gi|51702521 POU domain, class 3, transcription factor 2 [Homo sa...    63   5e-10
gi|110624765 POU domain, class 3, transcription factor 1 [Homo s...    62   8e-10
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    61   1e-09
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       59   9e-09
gi|20070107 orthodenticle homeobox 1 [Homo sapiens]                    57   3e-08
gi|122937233 discs, large (Drosophila) homolog-associated protei...    55   7e-08
gi|40288197 GATA binding protein 6 [Homo sapiens]                      54   2e-07
gi|22748877 basic helix-loop-helix domain containing, class B, 5...    52   6e-07
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    52   6e-07
gi|61966923 forkhead box B2 [Homo sapiens]                             52   6e-07
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    52   6e-07
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    52   6e-07
gi|110347449 POU domain, class 4, transcription factor 1 [Homo s...    52   8e-07
gi|4504809 jun B proto-oncogene [Homo sapiens]                         52   1e-06

>gi|71274111 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           A [Homo sapiens]
          Length = 353

 Score =  747 bits (1928), Expect = 0.0
 Identities = 353/353 (100%), Positives = 353/353 (100%)

Query: 1   MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCS 60
           MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCS
Sbjct: 1   MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCS 60

Query: 61  SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMS 120
           SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMS
Sbjct: 61  SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMS 120

Query: 121 GYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDM 180
           GYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDM
Sbjct: 121 GYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDM 180

Query: 181 GAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVREL 240
           GAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVREL
Sbjct: 181 GAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVREL 240

Query: 241 NRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEV 300
           NRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEV
Sbjct: 241 NRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEV 300

Query: 301 GRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL 353
           GRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL
Sbjct: 301 GRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGPGGAKGTADFFL 353


>gi|73427806 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform b [Homo sapiens]
          Length = 373

 Score =  319 bits (818), Expect = 2e-87
 Identities = 197/399 (49%), Positives = 224/399 (56%), Gaps = 94/399 (23%)

Query: 1   MAAELAMG-AELPSSPLAIEYVNDFDLMKFEVKKEPPEAERF---CHRL-PPGSLSSTPL 55
           MA+ELAM  ++LP+SPLA+EYVNDFDLMKFEVKKEP E +R    C RL   GSLSSTP+
Sbjct: 1   MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPM 60

Query: 56  STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED 115
           STPCSSVP SPSF APSPG+G                              +  K  LED
Sbjct: 61  STPCSSVPPSPSFSAPSPGSG------------------------------SEQKAHLED 90

Query: 116 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHH--GAHHGAHHPAAAAAYEAFRGPGFAG 173
            YWM+GY   LNPEAL  +PEDAVEALI + H   G   G    A   A  A  G G + 
Sbjct: 91  YYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASL 150

Query: 174 GGGADDMG--------------AGHHHGAHHAAHHHHAAHHHHHHHH------------- 206
           GG  ++MG              A    G H+  HHHHAA HHHH                
Sbjct: 151 GGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASA 210

Query: 207 ------------HHGGAGHGGGAG--------------HH----VRLEERFSDDQLVSMS 236
                         GG G GGG G              HH    +  ++RFSD+QLV+MS
Sbjct: 211 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMS 270

Query: 237 VRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQL 296
           VRELNRQLRG SKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRH+LESEK QL  QV+ L
Sbjct: 271 VRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHL 330

Query: 297 KLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREP 335
           K E+ RL +ERD YKEKYEKL   G   +   +  P  P
Sbjct: 331 KQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSP 369


>gi|5453736 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           isoform a [Homo sapiens]
          Length = 403

 Score =  319 bits (818), Expect = 2e-87
 Identities = 197/399 (49%), Positives = 224/399 (56%), Gaps = 94/399 (23%)

Query: 1   MAAELAMG-AELPSSPLAIEYVNDFDLMKFEVKKEPPEAERF---CHRL-PPGSLSSTPL 55
           MA+ELAM  ++LP+SPLA+EYVNDFDLMKFEVKKEP E +R    C RL   GSLSSTP+
Sbjct: 1   MASELAMSNSDLPTSPLAMEYVNDFDLMKFEVKKEPVETDRIISQCGRLIAGGSLSSTPM 60

Query: 56  STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED 115
           STPCSSVP SPSF APSPG+G                              +  K  LED
Sbjct: 61  STPCSSVPPSPSFSAPSPGSG------------------------------SEQKAHLED 90

Query: 116 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHH--GAHHGAHHPAAAAAYEAFRGPGFAG 173
            YWM+GY   LNPEAL  +PEDAVEALI + H   G   G    A   A  A  G G + 
Sbjct: 91  YYWMTGYPQQLNPEALGFSPEDAVEALISNSHQLQGGFDGYARGAQQLAAAAGAGAGASL 150

Query: 174 GGGADDMG--------------AGHHHGAHHAAHHHHAAHHHHHHHH------------- 206
           GG  ++MG              A    G H+  HHHHAA HHHH                
Sbjct: 151 GGSGEEMGPAAAVVSAVIAAAAAQSGAGPHYHHHHHHAAGHHHHPTAGAPGAAGSAAASA 210

Query: 207 ------------HHGGAGHGGGAG--------------HH----VRLEERFSDDQLVSMS 236
                         GG G GGG G              HH    +  ++RFSD+QLV+MS
Sbjct: 211 GGAGGAGGGGPASAGGGGGGGGGGGGGGAAGAGGALHPHHAAGGLHFDDRFSDEQLVTMS 270

Query: 237 VRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQL 296
           VRELNRQLRG SKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRH+LESEK QL  QV+ L
Sbjct: 271 VRELNRQLRGVSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHVLESEKNQLLQQVDHL 330

Query: 297 KLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREP 335
           K E+ RL +ERD YKEKYEKL   G   +   +  P  P
Sbjct: 331 KQEISRLVRERDAYKEKYEKLVSSGFRENGSSSDNPSSP 369


>gi|23308699 transcription factor MAFB [Homo sapiens]
          Length = 323

 Score =  306 bits (783), Expect = 2e-83
 Identities = 192/377 (50%), Positives = 215/377 (57%), Gaps = 100/377 (26%)

Query: 1   MAAELAMGAELPSSPLAIEYVNDFDLMKFEVKKEP----PEAERFCHRLPP-GSLSSTPL 55
           MAAEL+MG ELP+SPLA+EYVNDFDL+KF+VKKEP        R C RL P GS+SSTPL
Sbjct: 1   MAAELSMGPELPTSPLAMEYVNDFDLLKFDVKKEPLGRAERPGRPCTRLQPAGSVSSTPL 60

Query: 56  STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALED 115
           STPCSSVPSSPSF   SP                                 T  K  LED
Sbjct: 61  STPCSSVPSSPSF---SP---------------------------------TEQKTHLED 84

Query: 116 LYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGG 175
           LYWM+     +NPEALNLTPEDAVEALIGS      H    P  +  +++FRG       
Sbjct: 85  LYWMASNYQQMNPEALNLTPEDAVEALIGS------HPVPQPLQS--FDSFRG------- 129

Query: 176 GADDMGAGHHHGAHHAAHHHHA--------------AHHHHHHHHH-------------- 207
                   HHH  HH  H HHA              AH HHHHHH               
Sbjct: 130 -------AHHHHHHHHPHPHHAYPGAGVAHDELGPHAHPHHHHHHQASPPPSSAASPAQQ 182

Query: 208 ----HGGAG-----HGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQK 258
               H G G         AG +  +E+RFSDDQLVSMSVRELNR LRGF+K+EVIRLKQK
Sbjct: 183 LPTSHPGPGPHATASATAAGGNGSVEDRFSDDQLVSMSVRELNRHLRGFTKDEVIRLKQK 242

Query: 259 RRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKLA 318
           RRTLKNRGYAQSCR+KRVQQ+H LE+EK QL  QVEQLK EV RLA+ERD YK K EKLA
Sbjct: 243 RRTLKNRGYAQSCRYKRVQQKHHLENEKTQLIQQVEQLKQEVSRLARERDAYKVKCEKLA 302

Query: 319 GRGGPGSAGGAGFPREP 335
             G   +   +  P  P
Sbjct: 303 NSGFREAGSTSDSPSSP 319


>gi|5453802 neural retina leucine zipper [Homo sapiens]
          Length = 237

 Score =  199 bits (506), Expect = 3e-51
 Identities = 134/317 (42%), Positives = 169/317 (53%), Gaps = 92/317 (29%)

Query: 11  LPSSPLAIEYVNDFDLMKFEVKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCA 70
           LP SPLA+EYVNDFDLMKFEVK+EP E         PG  +++  STP SSVP SP+F  
Sbjct: 3   LPPSPLAMEYVNDFDLMKFEVKREPSEGR-------PGPPTASLGSTPYSSVPPSPTFSE 55

Query: 71  PSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG-KPALEDLYWMSGYQHHLNP- 128
           P                              G VG T G +P LE+LYW++  Q  L   
Sbjct: 56  P------------------------------GMVGATEGTRPGLEELYWLATLQQQLGAG 85

Query: 129 EALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGAGHHHGA 188
           EAL L+PE+A+E L G                      +GP    G              
Sbjct: 86  EALGLSPEEAMELLQG----------------------QGPVPVDGP------------- 110

Query: 189 HHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFS 248
                           H ++ G+    GA  HV+L ERFSD  LVSMSVRELNRQLRG  
Sbjct: 111 ----------------HGYYPGSPEETGA-QHVQLAERFSDAALVSMSVRELNRQLRGCG 153

Query: 249 KEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERD 308
           ++E +RLKQ+RRTLKNRGYAQ+CR KR+QQR  LE+E+ +L +Q++ L+ EV RLA+ERD
Sbjct: 154 RDEALRLKQRRRTLKNRGYAQACRSKRLQQRRGLEAERARLAAQLDALRAEVARLARERD 213

Query: 309 LYKEKYEKLAGRGGPGS 325
           LYK + ++L    GPGS
Sbjct: 214 LYKARCDRLTS-SGPGS 229


>gi|4505075 v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
           [Homo sapiens]
          Length = 156

 Score =  108 bits (269), Expect = 9e-24
 Identities = 55/90 (61%), Positives = 67/90 (74%)

Query: 228 SDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKC 287
           SDD+LVSMSVRELN+ LRG +KEEV RLKQ+RRTLKNRGYA SCR KRV Q+  LE ++ 
Sbjct: 25  SDDELVSMSVRELNQHLRGLTKEEVTRLKQRRRTLKNRGYAASCRIKRVTQKEELERQRV 84

Query: 288 QLQSQVEQLKLEVGRLAKERDLYKEKYEKL 317
           +LQ +VE+L  E   +  E D  + KYE L
Sbjct: 85  ELQQEVEKLARENSSMRLELDALRSKYEAL 114


>gi|4505073 v-maf musculoaponeurotic fibrosarcoma oncogene homolog G
           [Homo sapiens]
          Length = 162

 Score =  107 bits (266), Expect = 2e-23
 Identities = 57/115 (49%), Positives = 73/115 (63%), Gaps = 7/115 (6%)

Query: 228 SDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKC 287
           +D++LV+MSVRELN+ LRG SKEE+++LKQ+RRTLKNRGYA SCR KRV Q+  LE +K 
Sbjct: 25  TDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKA 84

Query: 288 QLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGP 342
           +LQ +VE+L  E   +  E D  + KYE L               R P  P  GP
Sbjct: 85  ELQQEVEKLASENASMKLELDALRSKYEAL-------QTFARTVARSPVAPARGP 132


>gi|49619228 v-maf musculoaponeurotic fibrosarcoma oncogene homolog
           G [Homo sapiens]
          Length = 162

 Score =  107 bits (266), Expect = 2e-23
 Identities = 57/115 (49%), Positives = 73/115 (63%), Gaps = 7/115 (6%)

Query: 228 SDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKC 287
           +D++LV+MSVRELN+ LRG SKEE+++LKQ+RRTLKNRGYA SCR KRV Q+  LE +K 
Sbjct: 25  TDEELVTMSVRELNQHLRGLSKEEIVQLKQRRRTLKNRGYAASCRVKRVTQKEELEKQKA 84

Query: 288 QLQSQVEQLKLEVGRLAKERDLYKEKYEKLAGRGGPGSAGGAGFPREPSPPQAGP 342
           +LQ +VE+L  E   +  E D  + KYE L               R P  P  GP
Sbjct: 85  ELQQEVEKLASENASMKLELDALRSKYEAL-------QTFARTVARSPVAPARGP 132


>gi|239048388 transcription factor MAFF isoform a [Homo sapiens]
          Length = 164

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 61/137 (44%), Positives = 76/137 (55%), Gaps = 15/137 (10%)

Query: 228 SDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKC 287
           SD+ L+ +SVRELNR LRG S EEV RLKQ+RRTLKNRGYA SCR KRV Q+  L+ +K 
Sbjct: 25  SDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKS 84

Query: 288 QLQSQVEQLKLEVGRLAKERDLYKEKYEKLAG--RGGPGSAGGA-------------GFP 332
           +L+ +V++L  E   +  E D  + K E L G  R    + G A               P
Sbjct: 85  ELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTP 144

Query: 333 REPSPPQAGPGGAKGTA 349
              S P  GP  A G A
Sbjct: 145 GSGSGPAHGPDPAHGPA 161


>gi|239048350 transcription factor MAFF isoform a [Homo sapiens]
          Length = 164

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 61/137 (44%), Positives = 76/137 (55%), Gaps = 15/137 (10%)

Query: 228 SDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKC 287
           SD+ L+ +SVRELNR LRG S EEV RLKQ+RRTLKNRGYA SCR KRV Q+  L+ +K 
Sbjct: 25  SDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKS 84

Query: 288 QLQSQVEQLKLEVGRLAKERDLYKEKYEKLAG--RGGPGSAGGA-------------GFP 332
           +L+ +V++L  E   +  E D  + K E L G  R    + G A               P
Sbjct: 85  ELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTP 144

Query: 333 REPSPPQAGPGGAKGTA 349
              S P  GP  A G A
Sbjct: 145 GSGSGPAHGPDPAHGPA 161


>gi|6912490 transcription factor MAFF isoform a [Homo sapiens]
          Length = 164

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 61/137 (44%), Positives = 76/137 (55%), Gaps = 15/137 (10%)

Query: 228 SDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKC 287
           SD+ L+ +SVRELNR LRG S EEV RLKQ+RRTLKNRGYA SCR KRV Q+  L+ +K 
Sbjct: 25  SDEALMGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKS 84

Query: 288 QLQSQVEQLKLEVGRLAKERDLYKEKYEKLAG--RGGPGSAGGA-------------GFP 332
           +L+ +V++L  E   +  E D  + K E L G  R    + G A               P
Sbjct: 85  ELEREVDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTP 144

Query: 333 REPSPPQAGPGGAKGTA 349
              S P  GP  A G A
Sbjct: 145 GSGSGPAHGPDPAHGPA 161


>gi|239048390 transcription factor MAFF isoform b [Homo sapiens]
          Length = 135

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 58/132 (43%), Positives = 72/132 (54%), Gaps = 15/132 (11%)

Query: 233 VSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQSCRFKRVQQRHILESEKCQLQSQ 292
           + +SVRELNR LRG S EEV RLKQ+RRTLKNRGYA SCR KRV Q+  L+ +K +L+ +
Sbjct: 1   MGLSVRELNRHLRGLSAEEVTRLKQRRRTLKNRGYAASCRVKRVCQKEELQKQKSELERE 60

Query: 293 VEQLKLEVGRLAKERDLYKEKYEKLAG--RGGPGSAGGA-------------GFPREPSP 337
           V++L  E   +  E D  + K E L G  R    + G A               P   S 
Sbjct: 61  VDKLARENAAMRLELDALRGKCEALQGFARSVAAARGPATLVAPASVITIVKSTPGSGSG 120

Query: 338 PQAGPGGAKGTA 349
           P  GP  A G A
Sbjct: 121 PAHGPDPAHGPA 132


>gi|110347455 Brn3b POU domain transcription factor [Homo sapiens]
          Length = 409

 Score = 75.1 bits (183), Expect = 9e-14
 Identities = 52/170 (30%), Positives = 60/170 (35%), Gaps = 9/170 (5%)

Query: 43  HRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPG 102
           H   PGS      S P +   SSPS  + + G GGGGG GGGGG   +  +    SGG G
Sbjct: 30  HSTSPGS------SAPIAPSASSPSSSSNAGGGGGGGGGGGGGGGRSSSSSSSGSSGGGG 83

Query: 103 AVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAA 162
           +                 G    L   A  L   D V       HH  HH    P A   
Sbjct: 84  SEAMRRACLPTPPSNIFGGLDESLLARAEALAAVDIVSQSKSHHHHPPHHSPFKPDAT-- 141

Query: 163 YEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAG 212
           Y             +  +   H   A    HHHH  HHHHHH  H    G
Sbjct: 142 YHTMNTIPCTSAASSSSVPISHP-SALAGTHHHHHHHHHHHHQPHQALEG 190


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 63/202 (31%), Positives = 73/202 (36%), Gaps = 36/202 (17%)

Query: 41  FCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGG---------GGAGGGGGSSQAG 91
           FC   PP +    P+ T     P  PS    + G                GG  GS++A 
Sbjct: 467 FCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAA 526

Query: 92  GAPGPP---------SGGPGAVGGTSGKPAL-EDLYWMSGYQHHLN--PEALNLTPEDAV 139
             PG P         SG P   GG   + AL E     SG        P A ++    A 
Sbjct: 527 PPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAG 586

Query: 140 EALIGSGHHGAHHGA-HHPAAAAAYEAFRGP-----GFAGGGGADDM---------GAGH 184
            A  GSG  G+   A HHP      +A  G       F   GG DD           AG 
Sbjct: 587 AAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGA 646

Query: 185 HHGAHHAAHHHHAAHHHHHHHH 206
            H A    HHHH  HHHHHHHH
Sbjct: 647 PHSAQTHPHHHHHPHHHHHHHH 668



 Score = 36.2 bits (82), Expect = 0.046
 Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 17/135 (12%)

Query: 54  PLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPAL 113
           P   P SSV ++    A +    GGGG  G        GAP PP   P  +   +G P  
Sbjct: 251 PACHPLSSVKAAA--VAAAAAVAGGGGLLG----PHLLGAPPPPPPPPPPLAELAGAP-- 302

Query: 114 EDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAG 173
                   + HH  P   +   +   EA + +    +   A    AAA+  A  G G AG
Sbjct: 303 --------HAHHKRPR-FDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAG 353

Query: 174 GGGADDMGAGHHHGA 188
           GG    +G G   GA
Sbjct: 354 GGCVAGVGVGAGAGA 368



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 37/123 (30%), Positives = 42/123 (34%), Gaps = 4/123 (3%)

Query: 60  SSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSG-GPGAVGGTSGKPALEDLYW 118
           S+  +S S  A S G G GGG  GGG  +  G   G  +G G GA G  S          
Sbjct: 330 SAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKG 389

Query: 119 MSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGAD 178
             G      P    L P         +     H       A AA EA  G G  G G A 
Sbjct: 390 SFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCH---KKEDAGAAAEALGGAGAGGAGAAP 446

Query: 179 DMG 181
             G
Sbjct: 447 KAG 449



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 14/50 (28%), Positives = 22/50 (44%)

Query: 60  SSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG 109
           +S+ ++ +  + +  +GG G  GGG G     G       G GA  G  G
Sbjct: 327 ASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKG 376


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 63/202 (31%), Positives = 73/202 (36%), Gaps = 36/202 (17%)

Query: 41  FCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGG---------GGAGGGGGSSQAG 91
           FC   PP +    P+ T     P  PS    + G                GG  GS++A 
Sbjct: 467 FCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAA 526

Query: 92  GAPGPP---------SGGPGAVGGTSGKPAL-EDLYWMSGYQHHLN--PEALNLTPEDAV 139
             PG P         SG P   GG   + AL E     SG        P A ++    A 
Sbjct: 527 PPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAG 586

Query: 140 EALIGSGHHGAHHGA-HHPAAAAAYEAFRGP-----GFAGGGGADDM---------GAGH 184
            A  GSG  G+   A HHP      +A  G       F   GG DD           AG 
Sbjct: 587 AAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGA 646

Query: 185 HHGAHHAAHHHHAAHHHHHHHH 206
            H A    HHHH  HHHHHHHH
Sbjct: 647 PHSAQTHPHHHHHPHHHHHHHH 668



 Score = 36.2 bits (82), Expect = 0.046
 Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 17/135 (12%)

Query: 54  PLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPAL 113
           P   P SSV ++    A +    GGGG  G        GAP PP   P  +   +G P  
Sbjct: 251 PACHPLSSVKAAA--VAAAAAVAGGGGLLG----PHLLGAPPPPPPPPPPLAELAGAP-- 302

Query: 114 EDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAG 173
                   + HH  P   +   +   EA + +    +   A    AAA+  A  G G AG
Sbjct: 303 --------HAHHKRPR-FDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAG 353

Query: 174 GGGADDMGAGHHHGA 188
           GG    +G G   GA
Sbjct: 354 GGCVAGVGVGAGAGA 368



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 37/123 (30%), Positives = 42/123 (34%), Gaps = 4/123 (3%)

Query: 60  SSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSG-GPGAVGGTSGKPALEDLYW 118
           S+  +S S  A S G G GGG  GGG  +  G   G  +G G GA G  S          
Sbjct: 330 SAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKG 389

Query: 119 MSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGAD 178
             G      P    L P         +     H       A AA EA  G G  G G A 
Sbjct: 390 SFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCH---KKEDAGAAAEALGGAGAGGAGAAP 446

Query: 179 DMG 181
             G
Sbjct: 447 KAG 449



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 14/50 (28%), Positives = 22/50 (44%)

Query: 60  SSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG 109
           +S+ ++ +  + +  +GG G  GGG G     G       G GA  G  G
Sbjct: 327 ASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKG 376


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 68.6 bits (166), Expect = 8e-12
 Identities = 63/202 (31%), Positives = 73/202 (36%), Gaps = 36/202 (17%)

Query: 41  FCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGG---------GGAGGGGGSSQAG 91
           FC   PP +    P+ T     P  PS    + G                GG  GS++A 
Sbjct: 467 FCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAA 526

Query: 92  GAPGPP---------SGGPGAVGGTSGKPAL-EDLYWMSGYQHHLN--PEALNLTPEDAV 139
             PG P         SG P   GG   + AL E     SG        P A ++    A 
Sbjct: 527 PPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAG 586

Query: 140 EALIGSGHHGAHHGA-HHPAAAAAYEAFRGP-----GFAGGGGADDM---------GAGH 184
            A  GSG  G+   A HHP      +A  G       F   GG DD           AG 
Sbjct: 587 AAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGA 646

Query: 185 HHGAHHAAHHHHAAHHHHHHHH 206
            H A    HHHH  HHHHHHHH
Sbjct: 647 PHSAQTHPHHHHHPHHHHHHHH 668



 Score = 36.2 bits (82), Expect = 0.046
 Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 17/135 (12%)

Query: 54  PLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPAL 113
           P   P SSV ++    A +    GGGG  G        GAP PP   P  +   +G P  
Sbjct: 251 PACHPLSSVKAAA--VAAAAAVAGGGGLLG----PHLLGAPPPPPPPPPPLAELAGAP-- 302

Query: 114 EDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAG 173
                   + HH  P   +   +   EA + +    +   A    AAA+  A  G G AG
Sbjct: 303 --------HAHHKRPR-FDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAG 353

Query: 174 GGGADDMGAGHHHGA 188
           GG    +G G   GA
Sbjct: 354 GGCVAGVGVGAGAGA 368



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 37/123 (30%), Positives = 42/123 (34%), Gaps = 4/123 (3%)

Query: 60  SSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSG-GPGAVGGTSGKPALEDLYW 118
           S+  +S S  A S G G GGG  GGG  +  G   G  +G G GA G  S          
Sbjct: 330 SAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKG 389

Query: 119 MSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGAD 178
             G      P    L P         +     H       A AA EA  G G  G G A 
Sbjct: 390 SFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCH---KKEDAGAAAEALGGAGAGGAGAAP 446

Query: 179 DMG 181
             G
Sbjct: 447 KAG 449



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 14/50 (28%), Positives = 22/50 (44%)

Query: 60  SSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG 109
           +S+ ++ +  + +  +GG G  GGG G     G       G GA  G  G
Sbjct: 327 ASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKG 376


>gi|51702521 POU domain, class 3, transcription factor 2 [Homo
           sapiens]
          Length = 443

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 73/252 (28%), Positives = 96/252 (38%), Gaps = 53/252 (21%)

Query: 74  GTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNL 133
           G GGGGG GGGGG    GG  G P      +G    KP++       G + H  P AL  
Sbjct: 69  GGGGGGGGGGGGGGGGGGGGDGSP-WSTSPLGQPDIKPSVVVQQGGRGDELH-GPGALQQ 126

Query: 134 TPEDAVEALIGSGH------------HGAHHGA-HHP------AAAAAYEAFRGPGFAGG 174
             +   +                   H  HH A HHP      +AAAA       G + G
Sbjct: 127 QHQQQQQQQQQQQQQQQQQQQQQRPPHLVHHAANHHPGPGAWRSAAAAAHLPPSMGASNG 186

Query: 175 G--------------GADDMGAG-HHHGAHHAAHH-HHAAHHHHHHHHHH---------- 208
           G              GA    AG HHHG   A    HHA HH H H H H          
Sbjct: 187 GLLYSQPSFTVNGMLGAGGQPAGLHHHGLRDAHDEPHHADHHPHPHSHPHQQPPPPPPPQ 246

Query: 209 GGAGHGGGAGHHVRLEERFSDDQLVSMSVRELNRQLR-GFSKEEVIRLKQKRRTLKNRGY 267
           G  GH G        E+  + D L   + +   R+++ GF++ +V        TL    +
Sbjct: 247 GPPGHPGAHHDPHSDEDTPTSDDLEQFAKQFKQRRIKLGFTQADV---GLALGTLYGNVF 303

Query: 268 AQS--CRFKRVQ 277
           +Q+  CRF+ +Q
Sbjct: 304 SQTTICRFEALQ 315


>gi|110624765 POU domain, class 3, transcription factor 1 [Homo
           sapiens]
          Length = 451

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 73/242 (30%), Positives = 95/242 (39%), Gaps = 53/242 (21%)

Query: 73  PGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG--------KPALEDLYWMSGYQ- 123
           P  GGGGG   GG   + G A G  +G     GG  G          A     W  G   
Sbjct: 75  PTGGGGGGDWAGGPHLEHGKAGGGGTGRADDGGGGGGFHARLVHQGAAHAGAAWAQGSTA 134

Query: 124 HHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAG-----GGGAD 178
           HHL P A++ +P  +       GH     G +   A AAY    G G AG     GGGA 
Sbjct: 135 HHLGP-AMSPSPGAS------GGHQPQPLGLY---AQAAYPGGGGGGLAGMLAAGGGGA- 183

Query: 179 DMGAGHHHGAHHAAHH---------HHAAHHHHHHHHH-----------HGGAGHGGGAG 218
             G G HH  H   H          H  AH H H H H           H GAG GG + 
Sbjct: 184 --GPGLHHALHEDGHEAQLEPSPPPHLGAHGHAHGHAHAGGLHAAAAHLHPGAGGGGSSV 241

Query: 219 HHVRLEERFSDDQLVSMSVRELNRQLR-GFSKEEVIRLKQKRRTLKNRGYAQS--CRFKR 275
                E+  S D L   + +   R+++ GF++ +V        TL    ++Q+  CRF+ 
Sbjct: 242 GEHSDEDAPSSDDLEQFAKQFKQRRIKLGFTQADV---GLALGTLYGNVFSQTTICRFEA 298

Query: 276 VQ 277
           +Q
Sbjct: 299 LQ 300



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 42/135 (31%), Positives = 47/135 (34%), Gaps = 30/135 (22%)

Query: 43  HRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPG 102
           H L P    S   S      P      A  PG GGGG A    G   AGG      GG G
Sbjct: 135 HHLGPAMSPSPGASGGHQPQPLGLYAQAAYPGGGGGGLA----GMLAAGG------GGAG 184

Query: 103 AVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAA 162
                   P L       G++  L P     +P   +      G HG  HG  H     A
Sbjct: 185 --------PGLHHALHEDGHEAQLEP-----SPPPHL------GAHGHAHGHAHAGGLHA 225

Query: 163 YEAFRGPGFAGGGGA 177
             A   PG AGGGG+
Sbjct: 226 AAAHLHPG-AGGGGS 239


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 61.2 bits (147), Expect = 1e-09
 Identities = 57/190 (30%), Positives = 65/190 (34%), Gaps = 43/190 (22%)

Query: 63  PSSPSFCAPSPGTGGGG---GAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLY-- 117
           P  P F     G  GGG   G GG GG    GG   P  G  G +G +SG    E     
Sbjct: 717 PPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGG 776

Query: 118 WMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHG---------AHHP--------AAA 160
             SG++ H  P            ++ G G H  H G          H P         A 
Sbjct: 777 MGSGHRPHEGPGG----------SMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAG 826

Query: 161 AAYEAFRGPGFA-GGGGADDMGAGHHHGAHHAAHHH----HAAHHHH----HHHHHHGGA 211
             +    GPG + GG G      G  HG  H    H    H  H H     H H  H G 
Sbjct: 827 GGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHDGP 886

Query: 212 GHG--GGAGH 219
           GHG  G  GH
Sbjct: 887 GHGGGGHRGH 896



 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 58/190 (30%), Positives = 64/190 (33%), Gaps = 25/190 (13%)

Query: 48  GSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQ----AGGAPGPPSG---- 99
           G     P   P        S   P  G GG GG   GGG  +     GG  G  SG    
Sbjct: 711 GGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPH 770

Query: 100 -GPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPA 158
            GPG   G+  +P       M G   H   E     P   +    GSGH           
Sbjct: 771 EGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEG----PGGGISG--GSGHRPHEGPGGGMG 824

Query: 159 AAAAYEAFRGPGFA-GGGGADDMGAGHHHGAHHAAHHH----HAAHHHH----HHHHHHG 209
           A   +    GPG + GG G      G  HG  H    H    H  H H     H H  H 
Sbjct: 825 AGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGHD 884

Query: 210 GAGHGGGAGH 219
           G GHGGG GH
Sbjct: 885 GPGHGGG-GH 893



 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 49/161 (30%), Positives = 54/161 (33%), Gaps = 40/161 (24%)

Query: 71  PSPGTGGGGGAGG----GGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHL 126
           P  G GGG G+G     G G S  GG    P  GPG  GG SG          SG++ H 
Sbjct: 769 PHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPG--GGISGG---------SGHRPHE 817

Query: 127 NPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAA----AAYEAFRGPGFAGGGGADDMGA 182
            P               G G  G H     P  +      +    GPG  G       G 
Sbjct: 818 GPGG-------------GMGAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGG-----PHGH 859

Query: 183 GHHHGAHHAAHHHHAAHHHHHHHHH---HGGAGHGGGAGHH 220
             H    H  H H     H H  H    HGG GH G  G H
Sbjct: 860 RPHDVPGHRGHDHRGPPPHEHRGHDGPGHGGGGHRGHDGGH 900



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 47/193 (24%), Positives = 53/193 (27%), Gaps = 37/193 (19%)

Query: 36  PEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGG--- 92
           P   +     PPG     P        P  P    P P   GG     G G    GG   
Sbjct: 634 PGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMR 693

Query: 93  -----APGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGH 147
                 PGP   G G  GG    P         G +    P      P      ++G G 
Sbjct: 694 GGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGG---MVGGGG 750

Query: 148 HGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHHHH 207
           H  H G   P       +   P    GGG   MG+GH                      H
Sbjct: 751 HRPHEG---PGGGMGNSSGHRPHEGPGGG---MGSGHRP--------------------H 784

Query: 208 HGGAGHGGGAGHH 220
            G  G  GG G H
Sbjct: 785 EGPGGSMGGGGGH 797



 Score = 33.5 bits (75), Expect = 0.30
 Identities = 49/201 (24%), Positives = 60/201 (29%), Gaps = 36/201 (17%)

Query: 49  SLSSTPLSTPCSSVPSSPSFC-------------APSPGTGGGGGAGGGGGSSQAGGAPG 95
           S+  +P S P   +   P +               P P   G    G GG        PG
Sbjct: 587 SIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPG 646

Query: 96  PPSGGPGAVGGTSG-----------KPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIG 144
           P    PG  GG  G            P   D +W  G    +    +   P        G
Sbjct: 647 PGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFW-DGPGDPMRGGPMRGGPGPGP----G 701

Query: 145 SGH--HGAHHGAHHPAAAAAYEAFRGPGFAGGG---GADDMGAGHHHGAHHAAHH-HHAA 198
             H   G   G   P     +   RG G +GGG   G    G G   G  H  H      
Sbjct: 702 PYHRGRGGRGGNEPPPPPPPFRGARG-GRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGG 760

Query: 199 HHHHHHHHHHGGAGHGGGAGH 219
             +   H  H G G G G+GH
Sbjct: 761 MGNSSGHRPHEGPGGGMGSGH 781


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 58.5 bits (140), Expect = 9e-09
 Identities = 74/287 (25%), Positives = 102/287 (35%), Gaps = 76/287 (26%)

Query: 50  LSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSG 109
           +++ P +   ++  ++ +  A SP +G     G  G   Q    P PP  GP   GG   
Sbjct: 98  VTALPHAAAAAAAAAAAAVEASSPWSGSA--VGMAGSPQQPPQPPPPPPQGPDVKGGAGR 155

Query: 110 KPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRG- 168
               +DL+  +   HH  P  L   P    +     GH G    A   AAAAA  A    
Sbjct: 156 ----DDLHAGTAL-HHRGPPHLGPPPPPPHQ-----GHPGGWGAAAAAAAAAAAAAAAAH 205

Query: 169 --------------------------------PGFAGGGGADDMGAG------------- 183
                                           PG  GGGG    GA              
Sbjct: 206 LPSMAGGQQPPPQSLLYSQPGGFTVNGMLSAPPGPGGGGGGAGGGAQSLVHPGLVRGDTP 265

Query: 184 ----HHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSD-DQLVSMSVR 238
               HHH  HH AH H    HH     HHGG   GGGAG  +   +  SD D   S  + 
Sbjct: 266 ELAEHHHHHHHHAHPHPPHPHHAQGPPHHGGG--GGGAGPGLNSHDPHSDEDTPTSDDLE 323

Query: 239 ELNRQLR------GFSKEEVIRLKQKRRTLKNRGYAQS--CRFKRVQ 277
           +  +Q +      GF++ +V        TL    ++Q+  CRF+ +Q
Sbjct: 324 QFAKQFKQRRIKLGFTQADV---GLALGTLYGNVFSQTTICRFEALQ 367



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 53/182 (29%), Positives = 61/182 (33%), Gaps = 33/182 (18%)

Query: 61  SVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMS 120
           S+  S +  A   G GGGGG GGG G    G  PG  +   GA  G      +    +M 
Sbjct: 20  SIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMVQSDFMQ 79

Query: 121 GYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAF-------------- 166
           G     N   +       V AL     H A   A   AAAAA EA               
Sbjct: 80  GAMAASNGGHMLSHAHQWVTAL----PHAA--AAAAAAAAAAVEASSPWSGSAVGMAGSP 133

Query: 167 -----------RGPGFAGGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGG 215
                      +GP   GG G DD+ AG     HH    H        H  H GG G   
Sbjct: 134 QQPPQPPPPPPQGPDVKGGAGRDDLHAG--TALHHRGPPHLGPPPPPPHQGHPGGWGAAA 191

Query: 216 GA 217
            A
Sbjct: 192 AA 193


>gi|20070107 orthodenticle homeobox 1 [Homo sapiens]
          Length = 354

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 65/258 (25%), Positives = 87/258 (33%), Gaps = 59/258 (22%)

Query: 1   MAAELAMGAELPSSPLAIEYVNDFDLMKFE------VKKEPPEAERFCHRLPPGSLSSTP 54
           M  E+A+   LP S + + + N     + +       K  P + +    R   GS SS  
Sbjct: 67  MREEVALKINLPESRVQVWFKNRRAKCRQQQQSGSGTKSRPAKKKSSPVRESSGSESSGQ 126

Query: 55  LSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALE 114
            + P  S  +S S  A S        A  G G            G P A   +   PA  
Sbjct: 127 FTPPAVSSSASSSSSASSSSANPAAAAAAGLG------------GNPVAAASSLSTPAAS 174

Query: 115 DLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGG 174
            ++  +       P ++++    A  +           GA    AAA+Y    G G + G
Sbjct: 175 SIWSPASISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGA--ATAAASYPMSYGQGGSYG 232

Query: 175 -----------GGADDMGA-----GHHH-------------GAHHAAHHHHA-------- 197
                      GG D          HHH             G HH  HH HA        
Sbjct: 233 QGYPTPSSSYFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHH--HHPHAHHPLSQSS 290

Query: 198 AHHHHHHHHHHGGAGHGG 215
            HHHHHHHHHH G G  G
Sbjct: 291 GHHHHHHHHHHQGYGGSG 308



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 24/138 (17%)

Query: 45  LPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGG-----GGGSSQAGGAPGPPSG 99
           + PGS  ++       + PS+ S    S   G    A       G G S   G P P S 
Sbjct: 182 ISPGSAPASVSVPEPLAAPSNTSCMQRSVAAGAATAAASYPMSYGQGGSYGQGYPTPSSS 241

Query: 100 GPGAVGGTSGKPALEDLYW-----------MSGYQHHLNPEALNLTPEDAVEALIGSGHH 148
             G V  +S    +   +            M+G+ HH +P A +   +        SGHH
Sbjct: 242 YFGGVDCSSYLAPMHSHHHPHQLSPMAPSSMAGHHHH-HPHAHHPLSQS-------SGHH 293

Query: 149 GAHHGAHHPAAAAAYEAF 166
             HH  HH     +  AF
Sbjct: 294 HHHHHHHHQGYGGSGLAF 311


>gi|122937233 discs, large (Drosophila) homolog-associated protein 3
           [Homo sapiens]
          Length = 979

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 55/200 (27%), Positives = 63/200 (31%), Gaps = 57/200 (28%)

Query: 64  SSPSFCAPSPGTG--------------------GGGGAGGGGGSS---QAGGAPGPPSGG 100
           + P FCAP  G G                    G  GAG GGGSS   +     GP    
Sbjct: 43  TEPRFCAPRAGLGHISPEGPLSLSEGPSVGPEGGPAGAGVGGGSSTFPRMYPGQGPFDTC 102

Query: 101 PGAVGGTSGK------PALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSG-------- 146
              VG   GK      P L D +     Q  +  +  +  P     A  G G        
Sbjct: 103 EDCVGHPQGKGAPRLPPTLLDQFEK---QLPVQQDGFHTLPYQRGPAGAGPGPAPGTGTA 159

Query: 147 -----------HHGAHH-----GAHHPAAAAAYEAFRGPGFAG-GGGADDMGAGHHHGAH 189
                       H  H         H   A     + GP   G GG   D   G   G  
Sbjct: 160 PEPRSESPSRIRHLVHSVQKLFAKSHSLEAPGKRDYNGPKAEGRGGSGGDSYPGPGSGGP 219

Query: 190 HAAHHHHAAHHHHHHHHHHG 209
           H +HHHH  HHHHHH   HG
Sbjct: 220 HTSHHHHHHHHHHHHQSRHG 239


>gi|40288197 GATA binding protein 6 [Homo sapiens]
          Length = 595

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 51/181 (28%), Positives = 65/181 (35%), Gaps = 54/181 (29%)

Query: 51  SSTPLSTPCSSVPSS-PSFCAPSPGTGGG-----GGAGGGGGSSQAGGAPGPPSGGPGAV 104
           +S+P+  P + V S  P       G+G G     GGAG   G  QA     P   G GA 
Sbjct: 183 ASSPVYVPTTRVGSMLPGLPYHLQGSGSGPANHAGGAGAHPGWPQASADSPPYGSGGGAA 242

Query: 105 GGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGA---HHPAAAA 161
           GG +  P                                G+G   AH  A   + P+   
Sbjct: 243 GGGAAGPG-------------------------------GAGSAAAHVSARFPYSPSPPM 271

Query: 162 AYEAFRGPG---FAGGGGADDMGAG-----------HHHGAHHAAHHHHAAHHHHHHHHH 207
           A  A R PG    AG GGA  +  G             + +  AA   +  +HHHHHHHH
Sbjct: 272 ANGAAREPGGYAAAGSGGAGGVSGGGSSLAAMGGREPQYSSLSAARPLNGTYHHHHHHHH 331

Query: 208 H 208
           H
Sbjct: 332 H 332



 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 43/144 (29%), Positives = 50/144 (34%), Gaps = 33/144 (22%)

Query: 63  PSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGY 122
           P  P   A SP  G GGGA GGG            + GPG  G  +   +    Y  S  
Sbjct: 223 PGWPQASADSPPYGSGGGAAGGG------------AAGPGGAGSAAAHVSARFPYSPS-- 268

Query: 123 QHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGA 182
                P A     E    A  GSG  G   G     AA      R P ++    A  +  
Sbjct: 269 ----PPMANGAAREPGGYAAAGSGGAGGVSGGGSSLAAM---GGREPQYSSLSAARPLNG 321

Query: 183 GHHHGAHHAAHHHHAAHHHHHHHH 206
            +HH            HHHHHHHH
Sbjct: 322 TYHH------------HHHHHHHH 333



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 29/106 (27%)

Query: 58  PCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLY 117
           P S  P   +  A  PG     G+GG GG           SGG  ++    G+       
Sbjct: 264 PYSPSPPMANGAAREPGGYAAAGSGGAGG----------VSGGGSSLAAMGGR------- 306

Query: 118 WMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAY 163
                     P+  +L+   A   L G+ HH  HH  HHP+  + Y
Sbjct: 307 ---------EPQYSSLS---AARPLNGTYHHHHHHHHHHPSPYSPY 340



 Score = 32.0 bits (71), Expect = 0.86
 Identities = 52/217 (23%), Positives = 65/217 (29%), Gaps = 55/217 (25%)

Query: 56  STPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPS----------------- 98
           STP S + SS S C+     G GG +  G        A GPP+                 
Sbjct: 33  STPPSPISSSSSSCSRGGERGPGGASNCGTPQLDTEAAAGPPARSLLLSSYASHPFGAPH 92

Query: 99  --GGPGAVGGTSGKPALEDLYWMSGYQH--------------HLNPEALNLTPEDAVEAL 142
               PG  G      + EDL   +                   L+P A    PE+  + L
Sbjct: 93  GPSAPGVAGPGGNLSSWEDLLLFTDLDQAATASKLLWSSRGAKLSPFAPE-QPEEMYQTL 151

Query: 143 IG------SGHHGAHHGAHHPAAAAAYEAFRG---------------PGFAGGGGADDMG 181
                   + + GA  G  H AAAAA  A                  PG          G
Sbjct: 152 AALSSQGPAAYDGAPGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPYHLQGSGSG 211

Query: 182 AGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAG 218
             +H G   A      A      +   GGA  GG AG
Sbjct: 212 PANHAGGAGAHPGWPQASADSPPYGSGGGAAGGGAAG 248



 Score = 29.3 bits (64), Expect = 5.6
 Identities = 17/37 (45%), Positives = 17/37 (45%), Gaps = 11/37 (29%)

Query: 319 GRGGPGSAGGAG------FPREPSPPQAG-----PGG 344
           G  GPG AG A       FP  PSPP A      PGG
Sbjct: 245 GAAGPGGAGSAAAHVSARFPYSPSPPMANGAAREPGG 281


>gi|22748877 basic helix-loop-helix domain containing, class B, 5
           [Homo sapiens]
          Length = 381

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 60/195 (30%), Positives = 66/195 (33%), Gaps = 46/195 (23%)

Query: 35  PPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAP 94
           PP  ER      P S SS+PL     + P       P PG GGGG AG GGG     G P
Sbjct: 48  PPPRER------PASSSSSPLGCFEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVP 101

Query: 95  GPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGA 154
           G   G      G  G P+L  L           P    L  +    A  GS    +  G 
Sbjct: 102 GLLVGS----AGVGGDPSLSSL-----------PAGAALCLKYGESASRGSVAESS-GGE 145

Query: 155 HHP-----------AAAAAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHHHAAHHHHH 203
             P             A   +    PG AGGGGA             AA     AH H  
Sbjct: 146 QSPDDDSDGRCELVLRAGVADPRASPG-AGGGGA------------KAAEGCSNAHLHGG 192

Query: 204 HHHHHGGAGHGGGAG 218
                GG G GGG G
Sbjct: 193 ASVPPGGLGGGGGGG 207



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 22/56 (39%), Positives = 26/56 (46%)

Query: 59  CSSVPSSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALE 114
           CS+         P  G GGGGG G   GSS  GG  G  SGG  +   +S K + E
Sbjct: 184 CSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKE 239



 Score = 32.7 bits (73), Expect = 0.50
 Identities = 19/39 (48%), Positives = 20/39 (51%), Gaps = 2/39 (5%)

Query: 72  SPGTGGGGGAGGGGGSSQA--GGAPGPPSGGPGAVGGTS 108
           SPG GGGG     G S+    GGA  PP G  G  GG S
Sbjct: 170 SPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGS 208



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 21/43 (48%), Positives = 22/43 (51%), Gaps = 5/43 (11%)

Query: 71  PSPGTG-GGGGAGGGGGSSQA---GGAPGPPSG-GPGAVGGTS 108
           P    G GGGGA    G S A   GGA  PP G G G  GG+S
Sbjct: 167 PRASPGAGGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSS 209


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 44/142 (30%), Positives = 52/142 (36%), Gaps = 38/142 (26%)

Query: 47  PGSLSSTPLSTPCSSVPSS-----PSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGP 101
           PGS+   PL       P+S     P +  P  G GGGGG GGGGGS   GG  G  +GG 
Sbjct: 219 PGSMD--PLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA 276

Query: 102 GAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAA 161
           GA G  +   A                         A  A  G G  G + G     ++A
Sbjct: 277 GA-GAVAAAAA-------------------------AAAAAAGGGGGGGYGG-----SSA 305

Query: 162 AYEAFRGPGFAGGGGADDMGAG 183
            Y     P   GGG     G G
Sbjct: 306 GYGVLSSPRQQGGGMMMGPGGG 327



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 16/21 (76%), Positives = 16/21 (76%)

Query: 185 HHGAHHAAHHHHAAHHHHHHH 205
           HH  HHA HHHH AHH HHHH
Sbjct: 26  HHHHHHAHHHHHHAHHLHHHH 46



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 18/25 (72%), Positives = 18/25 (72%), Gaps = 4/25 (16%)

Query: 184 HHHGAHHAAHHHHAAHHHHHHHHHH 208
           HHH  HH AHHHH  HH HH HHHH
Sbjct: 26  HHH--HHHAHHHH--HHAHHLHHHH 46



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 17/25 (68%), Positives = 17/25 (68%), Gaps = 4/25 (16%)

Query: 186 HGAHHAAHHHHAAHHHHH--HHHHH 208
           H  HH  HHHHA HHHHH  H HHH
Sbjct: 23  HQQHH--HHHHAHHHHHHAHHLHHH 45



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 3/57 (5%)

Query: 187 GAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVRELNRQ 243
           G   AA  H   HHHHH HHHH  A H     HH  L+++ +  Q      ++  +Q
Sbjct: 15  GEAPAAPPHQQHHHHHHAHHHHHHAHH---LHHHHALQQQLNQFQQQQQQQQQQQQQ 68



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 51/176 (28%), Positives = 62/176 (35%), Gaps = 36/176 (20%)

Query: 70  APSPGTGGGGGAGGGGGSSQAGG---APGPP----SGGPGAVGGTSGKPALEDLYWMSGY 122
           AP PG        GG   S AGG    PGPP     G         G+PA        G 
Sbjct: 89  APQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPA-------GGR 141

Query: 123 QHHLNPEALNLTPEDAVEALIGSGHHGA------HHGAHHPAAAAAYEAFRGPGFAGGGG 176
             H    AL  T +  V    G G   A      ++G+  PA+        GP F   GG
Sbjct: 142 YEHPGLGALG-TQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGP-GGRAGPCFDQHGG 199

Query: 177 ADDMGAGHHHGAHHAA----------HHHHAAHHHHHHHHHHG----GAGHGGGAG 218
               G G  H A  AA           + H  + +   +H+ G    GAG GGG G
Sbjct: 200 QQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 38/148 (25%), Positives = 54/148 (36%), Gaps = 16/148 (10%)

Query: 61  SVPSSPSFCAPSPGTGGGGGAGGGGGS--------SQAGG-APGPPSGGPGAVGGTSGKP 111
           +V ++ +  A + G GGGGG GG             Q GG   GP  GG  ++   +   
Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339

Query: 112 ALEDLYWMSGYQHHLNPEALNL-----TPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAF 166
           A       +G   H +     L     +P   + +  GS    +   A  P  +      
Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399

Query: 167 RGPGFAGGG--GADDMGAGHHHGAHHAA 192
              G A GG   A  MG G   GA +AA
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMGAQYAA 427



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 36/143 (25%), Positives = 44/143 (30%), Gaps = 31/143 (21%)

Query: 76  GGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTP 135
           GGGGG       +   G+  P SGGPG   G    P  +      G Q       ++   
Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASGGPGGRAG----PCFD----QHGGQQSPGMGMMHSAS 212

Query: 136 EDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHH 195
             A  A          H  +  +    Y  +  PG  GGGG    G G            
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG------------ 260

Query: 196 HAAHHHHHHHHHHGGAGHGGGAG 218
                        GG G GGGAG
Sbjct: 261 -----------GSGGGGGGGGAG 272


>gi|61966923 forkhead box B2 [Homo sapiens]
          Length = 432

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 19/33 (57%), Positives = 20/33 (60%)

Query: 173 GGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHH 205
           G G    +   HHH  HH  HHH AAHHHHHHH
Sbjct: 129 GAGPGGHLHPHHHHHPHHHHHHHAAAHHHHHHH 161



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 18/36 (50%), Positives = 19/36 (52%), Gaps = 3/36 (8%)

Query: 176 GADDMGAGHHHGAHHAAHHHHAAHHHHHHH---HHH 208
           G+     G   G H   HHHH  HHHHHHH   HHH
Sbjct: 122 GSTKSAPGAGPGGHLHPHHHHHPHHHHHHHAAAHHH 157



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 15/27 (55%), Positives = 15/27 (55%)

Query: 187 GAHHAAHHHHAAHHHHHHHHHHGGAGH 213
           GA    H H   HHH HHHHHH  A H
Sbjct: 129 GAGPGGHLHPHHHHHPHHHHHHHAAAH 155



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 15/27 (55%), Positives = 15/27 (55%), Gaps = 4/27 (14%)

Query: 194 HHHAAHHHHHHHHHHGGAGHGGGAGHH 220
           H H  HHHH HHHHH    H   A HH
Sbjct: 135 HLHPHHHHHPHHHHH----HHAAAHHH 157



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 17/39 (43%), Positives = 17/39 (43%), Gaps = 3/39 (7%)

Query: 182 AGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHH 220
           AG    A  A    H   HHHHH HHH    H   A HH
Sbjct: 121 AGSTKSAPGAGPGGHLHPHHHHHPHHH---HHHHAAAHH 156



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 11/22 (50%), Positives = 11/22 (50%)

Query: 199 HHHHHHHHHHGGAGHGGGAGHH 220
           H HHHHH HH    H     HH
Sbjct: 137 HPHHHHHPHHHHHHHAAAHHHH 158


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 44/142 (30%), Positives = 52/142 (36%), Gaps = 38/142 (26%)

Query: 47  PGSLSSTPLSTPCSSVPSS-----PSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGP 101
           PGS+   PL       P+S     P +  P  G GGGGG GGGGGS   GG  G  +GG 
Sbjct: 219 PGSMD--PLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA 276

Query: 102 GAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAA 161
           GA G  +   A                         A  A  G G  G + G     ++A
Sbjct: 277 GA-GAVAAAAA-------------------------AAAAAAGGGGGGGYGG-----SSA 305

Query: 162 AYEAFRGPGFAGGGGADDMGAG 183
            Y     P   GGG     G G
Sbjct: 306 GYGVLSSPRQQGGGMMMGPGGG 327



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 16/21 (76%), Positives = 16/21 (76%)

Query: 185 HHGAHHAAHHHHAAHHHHHHH 205
           HH  HHA HHHH AHH HHHH
Sbjct: 26  HHHHHHAHHHHHHAHHLHHHH 46



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 18/25 (72%), Positives = 18/25 (72%), Gaps = 4/25 (16%)

Query: 184 HHHGAHHAAHHHHAAHHHHHHHHHH 208
           HHH  HH AHHHH  HH HH HHHH
Sbjct: 26  HHH--HHHAHHHH--HHAHHLHHHH 46



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 17/25 (68%), Positives = 17/25 (68%), Gaps = 4/25 (16%)

Query: 186 HGAHHAAHHHHAAHHHHH--HHHHH 208
           H  HH  HHHHA HHHHH  H HHH
Sbjct: 23  HQQHH--HHHHAHHHHHHAHHLHHH 45



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 3/57 (5%)

Query: 187 GAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVRELNRQ 243
           G   AA  H   HHHHH HHHH  A H     HH  L+++ +  Q      ++  +Q
Sbjct: 15  GEAPAAPPHQQHHHHHHAHHHHHHAHH---LHHHHALQQQLNQFQQQQQQQQQQQQQ 68



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 51/176 (28%), Positives = 62/176 (35%), Gaps = 36/176 (20%)

Query: 70  APSPGTGGGGGAGGGGGSSQAGG---APGPP----SGGPGAVGGTSGKPALEDLYWMSGY 122
           AP PG        GG   S AGG    PGPP     G         G+PA        G 
Sbjct: 89  APQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPA-------GGR 141

Query: 123 QHHLNPEALNLTPEDAVEALIGSGHHGA------HHGAHHPAAAAAYEAFRGPGFAGGGG 176
             H    AL  T +  V    G G   A      ++G+  PA+        GP F   GG
Sbjct: 142 YEHPGLGALG-TQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGP-GGRAGPCFDQHGG 199

Query: 177 ADDMGAGHHHGAHHAA----------HHHHAAHHHHHHHHHHG----GAGHGGGAG 218
               G G  H A  AA           + H  + +   +H+ G    GAG GGG G
Sbjct: 200 QQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 38/148 (25%), Positives = 54/148 (36%), Gaps = 16/148 (10%)

Query: 61  SVPSSPSFCAPSPGTGGGGGAGGGGGS--------SQAGG-APGPPSGGPGAVGGTSGKP 111
           +V ++ +  A + G GGGGG GG             Q GG   GP  GG  ++   +   
Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339

Query: 112 ALEDLYWMSGYQHHLNPEALNL-----TPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAF 166
           A       +G   H +     L     +P   + +  GS    +   A  P  +      
Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399

Query: 167 RGPGFAGGG--GADDMGAGHHHGAHHAA 192
              G A GG   A  MG G   GA +AA
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMGAQYAA 427



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 36/143 (25%), Positives = 44/143 (30%), Gaps = 31/143 (21%)

Query: 76  GGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTP 135
           GGGGG       +   G+  P SGGPG   G    P  +      G Q       ++   
Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASGGPGGRAG----PCFD----QHGGQQSPGMGMMHSAS 212

Query: 136 EDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHH 195
             A  A          H  +  +    Y  +  PG  GGGG    G G            
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG------------ 260

Query: 196 HAAHHHHHHHHHHGGAGHGGGAG 218
                        GG G GGGAG
Sbjct: 261 -----------GSGGGGGGGGAG 272


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 44/142 (30%), Positives = 52/142 (36%), Gaps = 38/142 (26%)

Query: 47  PGSLSSTPLSTPCSSVPSS-----PSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGP 101
           PGS+   PL       P+S     P +  P  G GGGGG GGGGGS   GG  G  +GG 
Sbjct: 219 PGSMD--PLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA 276

Query: 102 GAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAA 161
           GA G  +   A                         A  A  G G  G + G     ++A
Sbjct: 277 GA-GAVAAAAA-------------------------AAAAAAGGGGGGGYGG-----SSA 305

Query: 162 AYEAFRGPGFAGGGGADDMGAG 183
            Y     P   GGG     G G
Sbjct: 306 GYGVLSSPRQQGGGMMMGPGGG 327



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 16/21 (76%), Positives = 16/21 (76%)

Query: 185 HHGAHHAAHHHHAAHHHHHHH 205
           HH  HHA HHHH AHH HHHH
Sbjct: 26  HHHHHHAHHHHHHAHHLHHHH 46



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 18/25 (72%), Positives = 18/25 (72%), Gaps = 4/25 (16%)

Query: 184 HHHGAHHAAHHHHAAHHHHHHHHHH 208
           HHH  HH AHHHH  HH HH HHHH
Sbjct: 26  HHH--HHHAHHHH--HHAHHLHHHH 46



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 17/25 (68%), Positives = 17/25 (68%), Gaps = 4/25 (16%)

Query: 186 HGAHHAAHHHHAAHHHHH--HHHHH 208
           H  HH  HHHHA HHHHH  H HHH
Sbjct: 23  HQQHH--HHHHAHHHHHHAHHLHHH 45



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 20/57 (35%), Positives = 27/57 (47%), Gaps = 3/57 (5%)

Query: 187 GAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAGHHVRLEERFSDDQLVSMSVRELNRQ 243
           G   AA  H   HHHHH HHHH  A H     HH  L+++ +  Q      ++  +Q
Sbjct: 15  GEAPAAPPHQQHHHHHHAHHHHHHAHH---LHHHHALQQQLNQFQQQQQQQQQQQQQ 68



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 51/176 (28%), Positives = 62/176 (35%), Gaps = 36/176 (20%)

Query: 70  APSPGTGGGGGAGGGGGSSQAGG---APGPP----SGGPGAVGGTSGKPALEDLYWMSGY 122
           AP PG        GG   S AGG    PGPP     G         G+PA        G 
Sbjct: 89  APQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDDAPPKMGEPA-------GGR 141

Query: 123 QHHLNPEALNLTPEDAVEALIGSGHHGA------HHGAHHPAAAAAYEAFRGPGFAGGGG 176
             H    AL  T +  V    G G   A      ++G+  PA+        GP F   GG
Sbjct: 142 YEHPGLGALG-TQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGP-GGRAGPCFDQHGG 199

Query: 177 ADDMGAGHHHGAHHAA----------HHHHAAHHHHHHHHHHG----GAGHGGGAG 218
               G G  H A  AA           + H  + +   +H+ G    GAG GGG G
Sbjct: 200 QQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGG 255



 Score = 37.4 bits (85), Expect = 0.020
 Identities = 38/148 (25%), Positives = 54/148 (36%), Gaps = 16/148 (10%)

Query: 61  SVPSSPSFCAPSPGTGGGGGAGGGGGS--------SQAGG-APGPPSGGPGAVGGTSGKP 111
           +V ++ +  A + G GGGGG GG             Q GG   GP  GG  ++   +   
Sbjct: 280 AVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGS 339

Query: 112 ALEDLYWMSGYQHHLNPEALNL-----TPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAF 166
           A       +G   H +     L     +P   + +  GS    +   A  P  +      
Sbjct: 340 AAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQA 399

Query: 167 RGPGFAGGG--GADDMGAGHHHGAHHAA 192
              G A GG   A  MG G   GA +AA
Sbjct: 400 AAAGAAAGGQQAAAGMGLGKDMGAQYAA 427



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 36/143 (25%), Positives = 44/143 (30%), Gaps = 31/143 (21%)

Query: 76  GGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTP 135
           GGGGG       +   G+  P SGGPG   G    P  +      G Q       ++   
Sbjct: 161 GGGGGPAAVPEFNNYYGSAAPASGGPGGRAG----PCFD----QHGGQQSPGMGMMHSAS 212

Query: 136 EDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHH 195
             A  A          H  +  +    Y  +  PG  GGGG    G G            
Sbjct: 213 AAAAGAPGSMDPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGG------------ 260

Query: 196 HAAHHHHHHHHHHGGAGHGGGAG 218
                        GG G GGGAG
Sbjct: 261 -----------GSGGGGGGGGAG 272


>gi|110347449 POU domain, class 4, transcription factor 1 [Homo
           sapiens]
          Length = 419

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 41/111 (36%), Positives = 45/111 (40%), Gaps = 6/111 (5%)

Query: 73  PGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALN 132
           PG GGG G GGG G    GG  G P GG G  GG     +      M    H  +P A  
Sbjct: 147 PGGGGGPGGGGGPGGGPGGGGGGGPGGGGGGPGGGLLGGSAHPHPHMHSLGHLSHPAA-- 204

Query: 133 LTPEDAVEALIGSGHHG-AHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGA 182
                A+    G  H G     AHH AAAAA  A  G   A    A  +GA
Sbjct: 205 ---AAAMNMPSGLPHPGLVAAAAHHGAAAAAAAAAAGQVAAASAAAAVVGA 252



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 10/10 (100%), Positives = 10/10 (100%)

Query: 198 AHHHHHHHHH 207
           AHHHHHHHHH
Sbjct: 99  AHHHHHHHHH 108



 Score = 33.1 bits (74), Expect = 0.39
 Identities = 39/148 (26%), Positives = 41/148 (27%), Gaps = 63/148 (42%)

Query: 64  SSPSFCAPSPGTGGGGGAGGGGGSSQAGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQ 123
           SSPS  A   G GG G A GGGG+            GPG  GG  G              
Sbjct: 121 SSPSL-ALMAGAGGAGAAAGGGGAHD----------GPGGGGGPGG-------------- 155

Query: 124 HHLNPEALNLTPEDAVEALIGSGHHGAHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGAG 183
                               G G  G                  GPG  GGGG    G G
Sbjct: 156 --------------------GGGPGG------------------GPGGGGGGGPGGGGGG 177

Query: 184 HHHGAHHAAHHHHAAHHHHHHHHHHGGA 211
              G    + H H   H   H  H   A
Sbjct: 178 PGGGLLGGSAHPHPHMHSLGHLSHPAAA 205



 Score = 32.3 bits (72), Expect = 0.66
 Identities = 9/9 (100%), Positives = 9/9 (100%)

Query: 200 HHHHHHHHH 208
           HHHHHHHHH
Sbjct: 100 HHHHHHHHH 108



 Score = 31.2 bits (69), Expect = 1.5
 Identities = 32/118 (27%), Positives = 39/118 (33%), Gaps = 32/118 (27%)

Query: 112 ALEDLYWMSGYQHHLNPEA----LNLTPEDAVEALIGSGHHGAHHGAHHPAAAAA--YEA 165
           A  D+    G  H   P+A    +N  P  +   +  + HH  HH  HH A       + 
Sbjct: 62  AAVDIAVSQGKSHPFKPDATYHTMNSVPCTSTSTVPLAHHHHHHH--HHQALEPGDLLDH 119

Query: 166 FRGPGFA-----GGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHHHHHGGAGHGGGAG 218
              P  A     GG GA   G G H G                     GG G GGG G
Sbjct: 120 ISSPSLALMAGAGGAGAAAGGGGAHDGP-------------------GGGGGPGGGGG 158



 Score = 30.8 bits (68), Expect = 1.9
 Identities = 11/21 (52%), Positives = 12/21 (57%)

Query: 201 HHHHHHHHGGAGHGGGAGHHV 221
           HHHHHHHH  A   G    H+
Sbjct: 100 HHHHHHHHHQALEPGDLLDHI 120



 Score = 29.6 bits (65), Expect = 4.3
 Identities = 17/48 (35%), Positives = 17/48 (35%), Gaps = 22/48 (45%)

Query: 192 AHHHHAAHHHHHHHHHHG--------------------GAGHGGGAGH 219
           AHHHH  HHHHH     G                    GA  GGG  H
Sbjct: 99  AHHHH--HHHHHQALEPGDLLDHISSPSLALMAGAGGAGAAAGGGGAH 144



 Score = 28.9 bits (63), Expect = 7.3
 Identities = 13/31 (41%), Positives = 16/31 (51%)

Query: 317 LAGRGGPGSAGGAGFPREPSPPQAGPGGAKG 347
           +AG GG G+A G G   +      GPGG  G
Sbjct: 128 MAGAGGAGAAAGGGGAHDGPGGGGGPGGGGG 158


>gi|4504809 jun B proto-oncogene [Homo sapiens]
          Length = 347

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 70/288 (24%), Positives = 112/288 (38%), Gaps = 44/288 (15%)

Query: 31  VKKEPPEAERFCHRLPPGSLSSTPLSTPCSSVPSSPSFCAPSPGTGGG-GGAGGGGGSSQ 89
           +K    E ER       G +++TP        P    F     G+GGG GGAGGG    Q
Sbjct: 80  LKLASSELERLIVPNSNGVITTTP-------TPPGQYFYPRGGGSGGGAGGAGGGVTEEQ 132

Query: 90  AGGAPGPPSGGPGAVGGTSGKPALEDLYWMSGYQHHLNPEALNLTPEDAVEALIGSGHHG 149
            G A G                AL+DL+ M+    H+ P  ++L       A    G  G
Sbjct: 133 EGFADGFVK-------------ALDDLHKMN----HVTPPNVSLGATGGPPA----GPGG 171

Query: 150 AHHGAHHPAAAAAYEAFRGPGFAGGGGADDMGAGHHHGAHHAAHHHHAAHHHHHHHHHHG 209
            + G   P       ++     + GG    +G G  +     ++  HA      H     
Sbjct: 172 VYAGPEPPPVYTNLSSYSPASASSGGAGAAVGTGSSYPTTTISYLPHAPPFAGGHP---- 227

Query: 210 GAGHGGGAGHHVRLEERFSDDQLVSMSVRELNRQLRGFSKEEVIRLKQKRRTLKNRGYAQ 269
            A  G G G     EE  +  +  S   R+    +   + E+  R+K +R+ L+NR  A 
Sbjct: 228 -AQLGLGRGASTFKEEPQTVPEARS---RDATPPVSPINMEDQERIKVERKRLRNRLAAT 283

Query: 270 SCRFKRVQQRHILESEKCQLQSQVEQLKLEVGRLAKERDLYKEKYEKL 317
            CR +++++         +L+ +V+ LK E   L+    L +E+  +L
Sbjct: 284 KCRKRKLER-------IARLEDKVKTLKAENAGLSSTAGLLREQVAQL 324


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,542,367
Number of Sequences: 37866
Number of extensions: 1323254
Number of successful extensions: 33696
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 758
Number of HSP's successfully gapped in prelim test: 702
Number of HSP's that attempted gapping in prelim test: 11634
Number of HSP's gapped (non-prelim): 12358
length of query: 353
length of database: 18,247,518
effective HSP length: 103
effective length of query: 250
effective length of database: 14,347,320
effective search space: 3586830000
effective search space used: 3586830000
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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