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Search of human proteins with 7110719
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7110719 dickkopf homolog 1 precursor [Homo sapiens]
(266 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7110719 dickkopf homolog 1 precursor [Homo sapiens] 569 e-162
gi|7657023 dickkopf homolog 2 precursor [Homo sapiens] 200 9e-52
gi|7657025 dickkopf homolog 4 precursor [Homo sapiens] 146 2e-35
gi|66346689 dickkopf homolog 3 precursor [Homo sapiens] 56 3e-08
gi|40548393 dickkopf homolog 3 precursor [Homo sapiens] 56 3e-08
gi|40548389 dickkopf homolog 3 precursor [Homo sapiens] 56 3e-08
gi|17530787 prokineticin 2 isoform b precursor [Homo sapiens] 42 7e-04
gi|14165282 prokineticin 1 [Homo sapiens] 39 0.006
gi|187167261 prokineticin 2 isoform a precursor [Homo sapiens] 38 0.010
gi|86990448 chromosome 1 open reading frame 187 [Homo sapiens] 37 0.014
gi|110347437 latent transforming growth factor beta binding prot... 33 0.20
gi|110347412 latent transforming growth factor beta binding prot... 33 0.20
gi|110347431 latent transforming growth factor beta binding prot... 33 0.20
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 33 0.26
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 32 0.44
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 32 0.44
gi|62122917 filaggrin family member 2 [Homo sapiens] 32 0.58
gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens] 32 0.58
gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens] 32 0.58
gi|167466169 growth arrest-specific 1 [Homo sapiens] 32 0.58
gi|56790935 hypothetical protein LOC85369 [Homo sapiens] 32 0.58
gi|4557317 annexin A11 [Homo sapiens] 32 0.75
gi|22165433 annexin A11 [Homo sapiens] 32 0.75
gi|22165431 annexin A11 [Homo sapiens] 32 0.75
gi|22027627 TNF receptor-associated factor 5 [Homo sapiens] 32 0.75
gi|77404348 TNF receptor-associated factor 5 [Homo sapiens] 32 0.75
gi|11321603 TNF receptor-associated factor 5 [Homo sapiens] 32 0.75
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 31 0.98
gi|145275213 coagulation factor XII precursor [Homo sapiens] 30 1.7
gi|66346695 fibrillin 2 precursor [Homo sapiens] 30 2.2
>gi|7110719 dickkopf homolog 1 precursor [Homo sapiens]
Length = 266
Score = 569 bits (1466), Expect = e-162
Identities = 266/266 (100%), Positives = 266/266 (100%)
Query: 1 MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAV 60
MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAV
Sbjct: 1 MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAV 60
Query: 61 SAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKR 120
SAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKR
Sbjct: 61 SAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKR 120
Query: 121 CMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYH 180
CMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYH
Sbjct: 121 CMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYH 180
Query: 181 TKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCG 240
TKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCG
Sbjct: 181 TKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCG 240
Query: 241 EGLSCRIQKDHHQASNSSRLHTCQRH 266
EGLSCRIQKDHHQASNSSRLHTCQRH
Sbjct: 241 EGLSCRIQKDHHQASNSSRLHTCQRH 266
>gi|7657023 dickkopf homolog 2 precursor [Homo sapiens]
Length = 259
Score = 200 bits (509), Expect = 9e-52
Identities = 109/244 (44%), Positives = 141/244 (57%), Gaps = 27/244 (11%)
Query: 31 ATLNSVLNSNAIKNLPPPLGGAAGHPGSAVSAAPG----ILYPGGNKYQTIDNYQPYPCA 86
A LNS+ +S LGG PG A + + G + + G K + + Q YPC+
Sbjct: 33 AKLNSIKSS---------LGGET--PGQAANRSAGMYQGLAFGGSKKGKNLG--QAYPCS 79
Query: 87 EDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHF 146
D+EC YC SP +G A C+ CR+++KRC R MCCP C NGIC+ ++
Sbjct: 80 SDKECEVGRYCHSPHQGSSA----CMVCRRKKKRCHRDGMCCPSTRCNNGICIPVTESIL 135
Query: 147 RGEI---EETITESFGNDH-STLD-GYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCC 201
I + T + H S D G+ +KM H KG EG CLRSSDC G CC
Sbjct: 136 TPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHTKMSHIKGHEGDPCLRSSDCIEGFCC 195
Query: 202 ARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCRIQKDHHQASNSSRLH 261
ARHFW+KICKPVL +G+VCTK R+KGSHGLEIFQRC C +GLSC++ KD S+ +RLH
Sbjct: 196 ARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCKVWKD-ATYSSKARLH 254
Query: 262 TCQR 265
CQ+
Sbjct: 255 VCQK 258
>gi|7657025 dickkopf homolog 4 precursor [Homo sapiens]
Length = 224
Score = 146 bits (368), Expect = 2e-35
Identities = 77/188 (40%), Positives = 97/188 (51%), Gaps = 15/188 (7%)
Query: 85 CAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQN 144
C D +C T ++C P C CR R+RC R AMCCPG C N +C + +
Sbjct: 41 CLSDTDCNTRKFCLQPRDEKP----FCATCRGLRRRCQRDAMCCPGTLCVNDVCTTMEDA 96
Query: 145 HFRGEIEETITESFGND------HSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASG 198
+E + E G H + +R K KGQEG CLR+ DC G
Sbjct: 97 --TPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPG 154
Query: 199 LCCARHFWSKICKPVLKEGQVCTKHRRKG-SHGLEIFQRCYCGEGLSCRIQKDHHQASNS 257
LCCARHFW+KICKPVL EGQVC++ K + EIFQRC CG GL CR Q ++
Sbjct: 155 LCCARHFWTKICKPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQLTSNR--QH 212
Query: 258 SRLHTCQR 265
+RL CQ+
Sbjct: 213 ARLRVCQK 220
>gi|66346689 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 56.2 bits (134), Expect = 3e-08
Identities = 47/177 (26%), Positives = 62/177 (35%), Gaps = 60/177 (33%)
Query: 83 YPCAEDEECGTDEYCASPTRGGDAGVQI-CLACRKRRKRCMRHAMCCPGNYCKNGICVSS 141
+ C DE+CG YC A Q C CR +R C R + CC C G C
Sbjct: 145 HECIIDEDCGPSMYCQF------ASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHC--- 195
Query: 142 DQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCC 201
+KM T+G G++C DC GLCC
Sbjct: 196 ----------------------------------TKMA-TRGSNGTICDNQRDCQPGLCC 220
Query: 202 A--RHFWSKICKPVLKEGQVCTKHRRKGSHGLEI----------FQRCYCGEGLSCR 246
A R +C P+ EG++C S L++ RC C GL C+
Sbjct: 221 AFQRGLLFPVCTPLPVEGELC---HDPASRLLDLITWELEPDGALDRCPCASGLLCQ 274
Score = 28.9 bits (63), Expect = 4.9
Identities = 19/94 (20%), Positives = 34/94 (36%), Gaps = 17/94 (18%)
Query: 173 TLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQV------------- 219
T+ + + +G+ C+ DC + C + C+P + +
Sbjct: 131 TVITSVGDEEGRRSHECIIDEDCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLC 190
Query: 220 ----CTKHRRKGSHGLEIFQRCYCGEGLSCRIQK 249
CTK +GS+G + C GL C Q+
Sbjct: 191 VWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQR 224
>gi|40548393 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 56.2 bits (134), Expect = 3e-08
Identities = 47/177 (26%), Positives = 62/177 (35%), Gaps = 60/177 (33%)
Query: 83 YPCAEDEECGTDEYCASPTRGGDAGVQI-CLACRKRRKRCMRHAMCCPGNYCKNGICVSS 141
+ C DE+CG YC A Q C CR +R C R + CC C G C
Sbjct: 145 HECIIDEDCGPSMYCQF------ASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHC--- 195
Query: 142 DQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCC 201
+KM T+G G++C DC GLCC
Sbjct: 196 ----------------------------------TKMA-TRGSNGTICDNQRDCQPGLCC 220
Query: 202 A--RHFWSKICKPVLKEGQVCTKHRRKGSHGLEI----------FQRCYCGEGLSCR 246
A R +C P+ EG++C S L++ RC C GL C+
Sbjct: 221 AFQRGLLFPVCTPLPVEGELC---HDPASRLLDLITWELEPDGALDRCPCASGLLCQ 274
Score = 28.9 bits (63), Expect = 4.9
Identities = 19/94 (20%), Positives = 34/94 (36%), Gaps = 17/94 (18%)
Query: 173 TLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQV------------- 219
T+ + + +G+ C+ DC + C + C+P + +
Sbjct: 131 TVITSVGDEEGRRSHECIIDEDCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLC 190
Query: 220 ----CTKHRRKGSHGLEIFQRCYCGEGLSCRIQK 249
CTK +GS+G + C GL C Q+
Sbjct: 191 VWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQR 224
>gi|40548389 dickkopf homolog 3 precursor [Homo sapiens]
Length = 350
Score = 56.2 bits (134), Expect = 3e-08
Identities = 47/177 (26%), Positives = 62/177 (35%), Gaps = 60/177 (33%)
Query: 83 YPCAEDEECGTDEYCASPTRGGDAGVQI-CLACRKRRKRCMRHAMCCPGNYCKNGICVSS 141
+ C DE+CG YC A Q C CR +R C R + CC C G C
Sbjct: 145 HECIIDEDCGPSMYCQF------ASFQYTCQPCRGQRMLCTRDSECCGDQLCVWGHC--- 195
Query: 142 DQNHFRGEIEETITESFGNDHSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCC 201
+KM T+G G++C DC GLCC
Sbjct: 196 ----------------------------------TKMA-TRGSNGTICDNQRDCQPGLCC 220
Query: 202 A--RHFWSKICKPVLKEGQVCTKHRRKGSHGLEI----------FQRCYCGEGLSCR 246
A R +C P+ EG++C S L++ RC C GL C+
Sbjct: 221 AFQRGLLFPVCTPLPVEGELC---HDPASRLLDLITWELEPDGALDRCPCASGLLCQ 274
Score = 28.9 bits (63), Expect = 4.9
Identities = 19/94 (20%), Positives = 34/94 (36%), Gaps = 17/94 (18%)
Query: 173 TLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQV------------- 219
T+ + + +G+ C+ DC + C + C+P + +
Sbjct: 131 TVITSVGDEEGRRSHECIIDEDCGPSMYCQFASFQYTCQPCRGQRMLCTRDSECCGDQLC 190
Query: 220 ----CTKHRRKGSHGLEIFQRCYCGEGLSCRIQK 249
CTK +GS+G + C GL C Q+
Sbjct: 191 VWGHCTKMATRGSNGTICDNQRDCQPGLCCAFQR 224
>gi|17530787 prokineticin 2 isoform b precursor [Homo sapiens]
Length = 108
Score = 41.6 bits (96), Expect = 7e-04
Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 189 CLRSSDCASGLCCARHFWSK---ICKPVLKEGQVCTKHRRK-GSHGLEIFQRCYCGEGLS 244
C + S C G+CCA W K IC P+ K G C RK G + C C GL+
Sbjct: 34 CDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKVPFFGRRMHHTCPCLPGLA 93
Query: 245 C 245
C
Sbjct: 94 C 94
>gi|14165282 prokineticin 1 [Homo sapiens]
Length = 105
Score = 38.5 bits (88), Expect = 0.006
Identities = 21/65 (32%), Positives = 30/65 (46%), Gaps = 12/65 (18%)
Query: 189 CLRSSDCASGLCCARHFW---SKICKPVLKEGQVCTKHRRKGSHGLEIFQR-----CYCG 240
C R C +G CCA W ++C P+ +EG+ C GSH + F++ C C
Sbjct: 26 CERDVQCGAGTCCAISLWLRGLRMCTPLGREGEEC----HPGSHKVPFFRKRKHHTCPCL 81
Query: 241 EGLSC 245
L C
Sbjct: 82 PNLLC 86
>gi|187167261 prokineticin 2 isoform a precursor [Homo sapiens]
Length = 129
Score = 37.7 bits (86), Expect = 0.010
Identities = 18/45 (40%), Positives = 22/45 (48%), Gaps = 3/45 (6%)
Query: 189 CLRSSDCASGLCCARHFWSK---ICKPVLKEGQVCTKHRRKGSHG 230
C + S C G+CCA W K IC P+ K G C RK + G
Sbjct: 34 CDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNFG 78
>gi|86990448 chromosome 1 open reading frame 187 [Homo sapiens]
Length = 349
Score = 37.4 bits (85), Expect = 0.014
Identities = 26/75 (34%), Positives = 31/75 (41%), Gaps = 14/75 (18%)
Query: 171 RTTLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHG 230
R LSS T EG C DC G CC L+E +CT H R ++
Sbjct: 256 RGKLSSDGNETSPAEGEPCDHHQDCLPGTCCD-----------LRE-HLCTPHNRGLNN- 302
Query: 231 LEIFQRCYCGEGLSC 245
+ F C C EGL C
Sbjct: 303 -KCFDDCMCVEGLRC 316
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 33.5 bits (75), Expect = 0.20
Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 46 PP--PLGGAAGHPGS-AVSAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTR 102
PP P G GS S APG P G +P PCA+ EC ++C
Sbjct: 776 PPCGPHGHCTNTEGSFRCSCAPGYRAPSG---------RPGPCADVNECLEGDFCFPHGE 826
Query: 103 GGDAGVQICLACR------KRRKRCMRHAMCCPGNYCKNGICVSSD 142
+ C R C+ C + C++GIC ++D
Sbjct: 827 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTD 872
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 33.5 bits (75), Expect = 0.20
Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 46 PP--PLGGAAGHPGS-AVSAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTR 102
PP P G GS S APG P G +P PCA+ EC ++C
Sbjct: 806 PPCGPHGHCTNTEGSFRCSCAPGYRAPSG---------RPGPCADVNECLEGDFCFPHGE 856
Query: 103 GGDAGVQICLACR------KRRKRCMRHAMCCPGNYCKNGICVSSD 142
+ C R C+ C + C++GIC ++D
Sbjct: 857 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTD 902
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 33.5 bits (75), Expect = 0.20
Identities = 28/106 (26%), Positives = 39/106 (36%), Gaps = 18/106 (16%)
Query: 46 PP--PLGGAAGHPGS-AVSAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTR 102
PP P G GS S APG P G +P PCA+ EC ++C
Sbjct: 843 PPCGPHGHCTNTEGSFRCSCAPGYRAPSG---------RPGPCADVNECLEGDFCFPHGE 893
Query: 103 GGDAGVQICLACR------KRRKRCMRHAMCCPGNYCKNGICVSSD 142
+ C R C+ C + C++GIC ++D
Sbjct: 894 CLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTD 939
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 33.1 bits (74), Expect = 0.26
Identities = 19/63 (30%), Positives = 23/63 (36%), Gaps = 1/63 (1%)
Query: 183 GQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEG 242
G G C + DC G C +C P + G C R+G G C CG G
Sbjct: 1424 GSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG-RSGATCNLDCRRGQFGPSCTLHCDCGGG 1482
Query: 243 LSC 245
C
Sbjct: 1483 ADC 1485
Score = 30.0 bits (66), Expect = 2.2
Identities = 17/60 (28%), Positives = 25/60 (41%), Gaps = 1/60 (1%)
Query: 186 GSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSC 245
G C + +C +G C S +C P + G C + ++G Q C C G SC
Sbjct: 953 GLDCRSACNCTAGAACDAVNGSCLC-PAGRRGPRCAETCPAHTYGHNCSQACACFNGASC 1011
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 32.3 bits (72), Expect = 0.44
Identities = 20/63 (31%), Positives = 25/63 (39%), Gaps = 1/63 (1%)
Query: 183 GQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEG 242
G G C ++ C G C S IC P+ G C + G+ G Q C CG G
Sbjct: 655 GHWGENCAQTCQCHHGGTCHPQDGSCIC-PLGWTGHHCLEGCPLGTFGANCSQPCQCGPG 713
Query: 243 LSC 245
C
Sbjct: 714 EKC 716
Score = 29.3 bits (64), Expect = 3.7
Identities = 21/77 (27%), Positives = 30/77 (38%), Gaps = 1/77 (1%)
Query: 169 SRRTTLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGS 228
+ RT S + ++G G C + C +G S C P G +C+ +G
Sbjct: 209 AERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWM-GTICSLPCPEGF 267
Query: 229 HGLEIFQRCYCGEGLSC 245
HG Q C C G C
Sbjct: 268 HGPNCSQECRCHNGGLC 284
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 32.3 bits (72), Expect = 0.44
Identities = 38/166 (22%), Positives = 49/166 (29%), Gaps = 36/166 (21%)
Query: 115 RKRRKRCMRHAMCCPGNY-------------CKNGICVSSDQNHFR-GEIEETITESFGN 160
R R R + CCPG Y C +G CVS D H G + +
Sbjct: 76 RGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDS 135
Query: 161 DHSTLDGYSRRTTLSSKMYH---------------------TKGQEGSVCLRSSDCASGL 199
DH +R + + + G G C C G
Sbjct: 136 DHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGA 195
Query: 200 CCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSC 245
C +C P G C + GSHG RC C G +C
Sbjct: 196 SCDPRAGECLCAPGYT-GVYCEELCPPGSHGAHCELRCPCQNGGTC 240
Score = 29.3 bits (64), Expect = 3.7
Identities = 19/63 (30%), Positives = 25/63 (39%), Gaps = 1/63 (1%)
Query: 183 GQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEG 242
G G C C +G C+ S CK +G CT G+ GL + C C G
Sbjct: 440 GTYGPNCSSICSCNNGGTCSPVDGSCTCKEGW-QGLDCTLPCPSGTWGLNCNESCTCANG 498
Query: 243 LSC 245
+C
Sbjct: 499 AAC 501
Score = 29.3 bits (64), Expect = 3.7
Identities = 19/63 (30%), Positives = 23/63 (36%), Gaps = 1/63 (1%)
Query: 183 GQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEG 242
G G C S CA+G C+ S C P G C G+ GL + C C
Sbjct: 483 GTWGLNCNESCTCANGAACSPIDGSCSCTPGWL-GDTCELPCPDGTFGLNCSEHCDCSHA 541
Query: 243 LSC 245
C
Sbjct: 542 DGC 544
Score = 29.3 bits (64), Expect = 3.7
Identities = 16/60 (26%), Positives = 23/60 (38%), Gaps = 1/60 (1%)
Query: 186 GSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSC 245
G C + C +G C+ + C P G CT+ G + + C C G SC
Sbjct: 703 GPACFHACSCHNGASCSAEDGACHCTPGWT-GLFCTQRCPAAFFGKDCGRVCQCQNGASC 761
Score = 28.9 bits (63), Expect = 4.9
Identities = 18/63 (28%), Positives = 23/63 (36%), Gaps = 1/63 (1%)
Query: 183 GQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEG 242
G G+ C C +G C H + P G VC + G+ G Q C C G
Sbjct: 222 GSHGAHCELRCPCQNGGTC-HHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHG 280
Query: 243 LSC 245
C
Sbjct: 281 GQC 283
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 32.0 bits (71), Expect = 0.58
Identities = 34/155 (21%), Positives = 51/155 (32%), Gaps = 3/155 (1%)
Query: 51 GAAGHPGSAVSAAPGILYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQI 110
G G+ S + + GG + + QP C + E + + G Q
Sbjct: 304 GGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARENGQP 363
Query: 111 CLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITESFGNDHSTLDGYSR 170
C + + + CC G Y G S+ H G S N+ S D Y
Sbjct: 364 -QNCGGQWRTGSSQSSCC-GQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGS 421
Query: 171 RTTLSSKM-YHTKGQEGSVCLRSSDCASGLCCARH 204
++ S+ H G S C SG C +H
Sbjct: 422 GSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQH 456
>gi|193082982 zinc finger protein 837 isoform 1 [Homo sapiens]
Length = 531
Score = 32.0 bits (71), Expect = 0.58
Identities = 31/116 (26%), Positives = 41/116 (35%), Gaps = 15/116 (12%)
Query: 47 PPLGGAAGHPGSAVSAAPGILYPGGNKYQTIDNYQPYPCAEDEEC------GTDEYCASP 100
PP GG+ G VS PG + G + + P E + C SP
Sbjct: 60 PPGGGSRGC-SLGVSPGPGTRHSAGTRPLVREPCGPTSSQNPELVIPEGLQAREGPCRSP 118
Query: 101 TRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITE 156
RGGD CLA + +C P C QNH R ++ E T+
Sbjct: 119 ARGGDCSRNSCLAWHRGAPAGETPPVCDP--------CPERIQNHPRTQLCEVHTD 166
>gi|193082980 zinc finger protein 837 isoform 2 [Homo sapiens]
Length = 531
Score = 32.0 bits (71), Expect = 0.58
Identities = 31/116 (26%), Positives = 41/116 (35%), Gaps = 15/116 (12%)
Query: 47 PPLGGAAGHPGSAVSAAPGILYPGGNKYQTIDNYQPYPCAEDEEC------GTDEYCASP 100
PP GG+ G VS PG + G + + P E + C SP
Sbjct: 60 PPGGGSRGC-SLGVSPGPGTRHSAGTRPLVREPCGPTSSQNPELVIPEGLQAREGPCRSP 118
Query: 101 TRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEIEETITE 156
RGGD CLA + +C P C QNH R ++ E T+
Sbjct: 119 ARGGDCSRNSCLAWHRGAPAGETPPVCDP--------CPERIQNHPRTQLCEVHTD 166
>gi|167466169 growth arrest-specific 1 [Homo sapiens]
Length = 345
Score = 32.0 bits (71), Expect = 0.58
Identities = 23/100 (23%), Positives = 38/100 (38%), Gaps = 23/100 (23%)
Query: 51 GAAGHPGSAVSAAPGILYPGGNKYQT----------IDNYQPYPCAEDEECGTDEYCASP 100
G PG+A +A P ++++ +++ + P ED +C DE C S
Sbjct: 80 GGGDAPGAAAAAFPASAASFSSRWRCPSHCISALIQLNHTRRGPALEDCDCAQDENCKST 139
Query: 101 TR-------------GGDAGVQICLACRKRRKRCMRHAMC 127
R G G + C + R+RC R + C
Sbjct: 140 KRAIEPCLPRTSGGGAGGPGAGGVMGCTEARRRCDRDSRC 179
>gi|56790935 hypothetical protein LOC85369 [Homo sapiens]
Length = 837
Score = 32.0 bits (71), Expect = 0.58
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 8/70 (11%)
Query: 36 VLNSNAIKNLPPPLGGAAGHPGSAVSAAPGILYPGG-------NKYQTIDNYQPYPCAED 88
++N+ + PPP AA P A AA G+L PGG N+ + + Y P E
Sbjct: 12 IVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLL-PGGKAREFNRNQRKDSEGYSESPDLEF 70
Query: 89 EECGTDEYCA 98
E TD++ A
Sbjct: 71 EYADTDKWAA 80
>gi|4557317 annexin A11 [Homo sapiens]
Length = 505
Score = 31.6 bits (70), Expect = 0.75
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 12/85 (14%)
Query: 14 VAMVAAALGGHPLLGVSATLNSVLNSNAIKNL---------PPPLGGAAGHPGSAVSAAP 64
VA A L G++A ++ + NL PP G G P SA P
Sbjct: 42 VATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVP 101
Query: 65 GI-LYP--GGNKYQTIDNYQPYPCA 86
+YP GGN + +Y PYP A
Sbjct: 102 PYGMYPPPGGNPPSRMPSYPPYPGA 126
>gi|22165433 annexin A11 [Homo sapiens]
Length = 505
Score = 31.6 bits (70), Expect = 0.75
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 12/85 (14%)
Query: 14 VAMVAAALGGHPLLGVSATLNSVLNSNAIKNL---------PPPLGGAAGHPGSAVSAAP 64
VA A L G++A ++ + NL PP G G P SA P
Sbjct: 42 VATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVP 101
Query: 65 GI-LYP--GGNKYQTIDNYQPYPCA 86
+YP GGN + +Y PYP A
Sbjct: 102 PYGMYPPPGGNPPSRMPSYPPYPGA 126
>gi|22165431 annexin A11 [Homo sapiens]
Length = 505
Score = 31.6 bits (70), Expect = 0.75
Identities = 26/85 (30%), Positives = 34/85 (40%), Gaps = 12/85 (14%)
Query: 14 VAMVAAALGGHPLLGVSATLNSVLNSNAIKNL---------PPPLGGAAGHPGSAVSAAP 64
VA A L G++A ++ + NL PP G G P SA P
Sbjct: 42 VATYAGQFNQDYLSGMAANMSGTFGGANMPNLYPGAPGAGYPPVPPGGFGQPPSAQQPVP 101
Query: 65 GI-LYP--GGNKYQTIDNYQPYPCA 86
+YP GGN + +Y PYP A
Sbjct: 102 PYGMYPPPGGNPPSRMPSYPPYPGA 126
>gi|22027627 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 31.6 bits (70), Expect = 0.75
Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 11/79 (13%)
Query: 69 PGGNKYQTIDNYQPY--PCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAM 126
PG N + YQ + C ++E C P D + +C+ R+++C+
Sbjct: 114 PGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCL---- 169
Query: 127 CCPGNYCKNGICVSSDQNH 145
YCK + V + QNH
Sbjct: 170 -----YCKKDVVVINLQNH 183
>gi|77404348 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 31.6 bits (70), Expect = 0.75
Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 11/79 (13%)
Query: 69 PGGNKYQTIDNYQPY--PCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAM 126
PG N + YQ + C ++E C P D + +C+ R+++C+
Sbjct: 114 PGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCL---- 169
Query: 127 CCPGNYCKNGICVSSDQNH 145
YCK + V + QNH
Sbjct: 170 -----YCKKDVVVINLQNH 183
>gi|11321603 TNF receptor-associated factor 5 [Homo sapiens]
Length = 557
Score = 31.6 bits (70), Expect = 0.75
Identities = 20/79 (25%), Positives = 33/79 (41%), Gaps = 11/79 (13%)
Query: 69 PGGNKYQTIDNYQPY--PCAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAM 126
PG N + YQ + C ++E C P D + +C+ R+++C+
Sbjct: 114 PGCNAKVILGRYQDHLQQCLFQPVQCSNEKCREPVLRKDLKEHLSASCQFRKEKCL---- 169
Query: 127 CCPGNYCKNGICVSSDQNH 145
YCK + V + QNH
Sbjct: 170 -----YCKKDVVVINLQNH 183
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 31.2 bits (69), Expect = 0.98
Identities = 21/81 (25%), Positives = 31/81 (38%), Gaps = 5/81 (6%)
Query: 186 GSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSC 245
G C+ + +C +G C+ + C P G CT+ G +G + C C G C
Sbjct: 709 GPNCIHTCNCHNGAFCSAYDGECKCTPGWT-GLYCTQRCPLGFYGKDCALICQCQNGADC 767
Query: 246 RIQKDHHQASNSSRLHTCQRH 266
DH + R RH
Sbjct: 768 ----DHISGQCTCRTGFMGRH 784
Score = 30.8 bits (68), Expect = 1.3
Identities = 22/77 (28%), Positives = 27/77 (35%), Gaps = 6/77 (7%)
Query: 182 KGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGE 241
+G G+ C + C +G C C P G C G HG + QRC C
Sbjct: 184 QGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYT-GAFCEDLCPPGKHGPQCEQRCPCQN 242
Query: 242 GLSCRIQKDHHQASNSS 258
G C HH S
Sbjct: 243 GGVC-----HHVTGECS 254
Score = 30.0 bits (66), Expect = 2.2
Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 1/63 (1%)
Query: 183 GQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEG 242
G+ G C + C +G C H + P G VC + +G G Q C C G
Sbjct: 228 GKHGPQCEQRCPCQNGGVC-HHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNG 286
Query: 243 LSC 245
+C
Sbjct: 287 GTC 289
Score = 29.6 bits (65), Expect = 2.9
Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 1/69 (1%)
Query: 183 GQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLEIFQRCYCGEG 242
G G C + C +G C + C P + G+ C + G++GL +RC C
Sbjct: 489 GTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWR-GEKCELPCQDGTYGLNCAERCDCSHA 547
Query: 243 LSCRIQKDH 251
C H
Sbjct: 548 DGCHPTTGH 556
>gi|145275213 coagulation factor XII precursor [Homo sapiens]
Length = 615
Score = 30.4 bits (67), Expect = 1.7
Identities = 41/178 (23%), Positives = 60/178 (33%), Gaps = 24/178 (13%)
Query: 83 YPCAEDEECGTDEYCAS-PTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKN----GI 137
+ C G +CA+ P D CL +K + C +H+ C G C N
Sbjct: 59 HKCTHKGRPGPQPWCATTPNFDQDQRWGYCLEPKKVKDHCSKHSPCQKGGTCVNMPSGPH 118
Query: 138 CVSSDQ---NHFRGE--IEETITESFGND---HSTLDGYSRRTTLSSKMYHTKGQEGSVC 189
C+ NH + E E + F + + T R H + C
Sbjct: 119 CLCPQHLTGNHCQKEKCFEPQLLRFFHKNEIWYRTEQAAVARCQCKGPDAHCQRLASQAC 178
Query: 190 LRSSDCASGLCCARHFWSKICK-PVLKEGQVCTKHRRKGSHGLEIFQRCYCGEGLSCR 246
R++ C G C ++C PV G C ++ CY G GLS R
Sbjct: 179 -RTNPCLHGGRCLEVEGHRLCHCPVGYTGAFC---------DVDTKASCYDGRGLSYR 226
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 30.0 bits (66), Expect = 2.2
Identities = 10/24 (41%), Positives = 14/24 (58%)
Query: 119 KRCMRHAMCCPGNYCKNGICVSSD 142
K C+ H C N C NG+C++ D
Sbjct: 613 KNCVDHDECTTTNMCLNGMCINED 636
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.134 0.435
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,362,756
Number of Sequences: 37866
Number of extensions: 673247
Number of successful extensions: 2402
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 38
Number of HSP's that attempted gapping in prelim test: 2311
Number of HSP's gapped (non-prelim): 115
length of query: 266
length of database: 18,247,518
effective HSP length: 100
effective length of query: 166
effective length of database: 14,460,918
effective search space: 2400512388
effective search space used: 2400512388
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.