Guide to the Human Genome
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Search of human proteins with 70995211

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70995211 peroxisomal enoyl-coenzyme A hydratase-like protein
[Homo sapiens]
         (328 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70995211 peroxisomal enoyl-coenzyme A hydratase-like protein ...   639   0.0  
gi|194097323 mitochondrial short-chain enoyl-coenzyme A hydratas...   100   2e-21
gi|4502327 AU RNA binding protein/enoyl-Coenzyme A hydratase pre...   100   2e-21
gi|221307494 chromodomain protein, Y chromosome-like isoform a [...    88   1e-17
gi|221136756 chromodomain protein, Y chromosome-like isoform d [...    88   1e-17
gi|221136753 chromodomain protein, Y chromosome-like isoform d [...    88   1e-17
gi|4757966 Y chromosome chromodomain protein 1, telomeric isofor...    81   1e-15
gi|25453481 Y chromosome chromodomain protein 1, telomeric isofo...    81   1e-15
gi|51538581 chromodomain protein, Y-linked, 1B isoform b [Homo s...    81   1e-15
gi|51538573 chromodomain protein, Y-linked, 1B isoform a [Homo s...    81   1e-15
gi|49355787 Y chromosome chromodomain protein 2B [Homo sapiens]        80   2e-15
gi|4757968 Y chromosome chromodomain protein 2A [Homo sapiens]         80   2e-15
gi|116235487 chromodomain protein, Y-like 2 [Homo sapiens]             79   6e-15
gi|20127408 mitochondrial trifunctional protein, alpha subunit p...    77   2e-14
gi|45643119 peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 [Hom...    77   2e-14
gi|31542718 enoyl Coenzyme A hydratase domain containing 3 [Homo...    75   1e-13
gi|68989263 enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A...    72   5e-13
gi|157694516 enoyl Coenzyme A hydratase domain containing 1 isof...    72   7e-13
gi|213417737 enoyl Coenzyme A hydratase domain containing 1 isof...    72   7e-13
gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2 [...    67   2e-11
gi|37594471 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1 [...    67   2e-11
gi|150378541 enoyl Coenzyme A hydratase domain containing 2 [Hom...    66   4e-11
gi|157694520 enoyl Coenzyme A hydratase domain containing 1 isof...    61   2e-09
gi|62530384 dodecenoyl-Coenzyme A delta isomerase precursor [Hom...    55   7e-08
gi|45643121 peroxisomal D3,D2-enoyl-CoA isomerase isoform 2 [Hom...    54   1e-07
gi|189571693 potassium channel tetramerisation domain containing...    29   5.0  
gi|189571691 potassium channel tetramerisation domain containing...    29   5.0  
gi|18860857 menin isoform 1 [Homo sapiens]                             29   6.6  
gi|18860855 menin isoform 1 [Homo sapiens]                             29   6.6  
gi|18860851 menin isoform 1 [Homo sapiens]                             29   6.6  

>gi|70995211 peroxisomal enoyl-coenzyme A hydratase-like protein
           [Homo sapiens]
          Length = 328

 Score =  639 bits (1649), Expect = 0.0
 Identities = 328/328 (100%), Positives = 328/328 (100%)

Query: 1   MAAGIVASRRLRDLLTRRLTGSNYPGLSISLRLTGSSAQEEASGVALGEAPDHSYESLRV 60
           MAAGIVASRRLRDLLTRRLTGSNYPGLSISLRLTGSSAQEEASGVALGEAPDHSYESLRV
Sbjct: 1   MAAGIVASRRLRDLLTRRLTGSNYPGLSISLRLTGSSAQEEASGVALGEAPDHSYESLRV 60

Query: 61  TSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDL 120
           TSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDL
Sbjct: 61  TSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDL 120

Query: 121 MDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVT 180
           MDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVT
Sbjct: 121 MDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVT 180

Query: 181 ACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGS 240
           ACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGS
Sbjct: 181 ACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGS 240

Query: 241 GLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMS 300
           GLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMS
Sbjct: 241 GLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMS 300

Query: 301 MLQTQDLVKSVQATTENKELKTVTFSKL 328
           MLQTQDLVKSVQATTENKELKTVTFSKL
Sbjct: 301 MLQTQDLVKSVQATTENKELKTVTFSKL 328


>gi|194097323 mitochondrial short-chain enoyl-coenzyme A hydratase 1
           precursor [Homo sapiens]
          Length = 290

 Score =  100 bits (249), Expect = 2e-21
 Identities = 69/250 (27%), Positives = 119/250 (47%), Gaps = 15/250 (6%)

Query: 70  VQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASDILQ 129
           +QLNRP   NA+      E+ +       D    A+V++G  K F AG D+ +M +   Q
Sbjct: 50  IQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQ 109

Query: 130 PKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQ 189
                            +++ + ++ + +  KPVIAAV+G   GGG +L   CDI Y  +
Sbjct: 110 DCYS-------------SKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156

Query: 190 DAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPD 249
            A F   E+ +G     G  QRL + +G +SL  E+  T  ++ A +A  +GLVS++ P 
Sbjct: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVG-KSLAMEMVLTGDRISAQDAKQAGLVSKICP- 214

Query: 250 KEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQDLVK 309
            E +++ A+  A +I+S S + V   K ++  + + ++ E          S   T D  +
Sbjct: 215 VETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKE 274

Query: 310 SVQATTENKE 319
            + A  E ++
Sbjct: 275 GMTAFVEKRK 284


>gi|4502327 AU RNA binding protein/enoyl-Coenzyme A hydratase
           precursor [Homo sapiens]
          Length = 339

 Score =  100 bits (248), Expect = 2e-21
 Identities = 90/324 (27%), Positives = 138/324 (42%), Gaps = 35/324 (10%)

Query: 18  RLTGSNYPGLSISLRLTGSSAQEEASGV---------ALGEAPDHSYESLRVTSAQKHVL 68
           RL  +    L   LRL GS A   A            A G AP   Y S   T  +  V 
Sbjct: 21  RLVAACSAWLCPGLRLPGSLAGRRAGPAIWAQGWVPAAGGPAPKRGYSSEMKTEDELRVR 80

Query: 69  HVQ----------LNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVI-SGAGKMFTAG 117
           H++          +NR   +N+++K   + + +  + +  D   R ++I S    +F AG
Sbjct: 81  HLEEENRGIVVLGINRAYGKNSLSKNLIKMLSKAVDALKSDKKVRTIIIRSEVPGIFCAG 140

Query: 118 IDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVD 177
            DL + A       G  V++I   + DI              P P IAA+ G  +GGG++
Sbjct: 141 ADLKERAKMSSSEVGPFVSKIRAVINDIAN-----------LPVPTIAAIDGLALGGGLE 189

Query: 178 LVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEA 237
           L  ACDIR  A  A   + E  + +    G  QRLP+ IG  SL  EL F+AR +   EA
Sbjct: 190 LALACDIRVAASSAKMGLVETKLAIIPGGGGTQRLPRAIG-MSLAKELIFSARVLDGKEA 248

Query: 238 LGSGLVSRVF---PDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYV 294
              GL+S V     + +     AL LA E   + PVA++  K+ +    +  +   L   
Sbjct: 249 KAVGLISHVLEQNQEGDAAYRKALDLAREFLPQGPVAMRVAKLAINQGMEVDLVTGLAIE 308

Query: 295 ASWNMSMLQTQDLVKSVQATTENK 318
            +     + T+D ++ + A  E +
Sbjct: 309 EACYAQTIPTKDRLEGLLAFKEKR 332


>gi|221307494 chromodomain protein, Y chromosome-like isoform a
           [Homo sapiens]
          Length = 544

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 62/218 (28%), Positives = 108/218 (49%), Gaps = 11/218 (5%)

Query: 60  VTSAQKHVLHVQLN-RPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGI 118
           V   Q    H+ L+ + ++ N++N    RE+    +  + D D + V++S  G +F  G+
Sbjct: 291 VVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAAD-DSKLVLLSAVGSVFCCGL 349

Query: 119 DLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDL 178
           D +     +     DD  R S  + + I  +  TF   +   KP+I AV+G  IG G  +
Sbjct: 350 DFIYFIRRLT----DDRKRESTKMAEAIRNFVNTFIQFK---KPIIVAVNGPAIGLGASI 402

Query: 179 VTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEAL 238
           +  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+  + RK+ A EA 
Sbjct: 403 LPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGAS-ANEMLLSGRKLTAQEAC 461

Query: 239 GSGLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTK 276
           G GLVS+VF       +  + +  E++S +PV ++ +K
Sbjct: 462 GKGLVSQVFWPGTFTQEVMVRI-KELASCNPVVLEESK 498


>gi|221136756 chromodomain protein, Y chromosome-like isoform d
           [Homo sapiens]
          Length = 412

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 62/218 (28%), Positives = 108/218 (49%), Gaps = 11/218 (5%)

Query: 60  VTSAQKHVLHVQLN-RPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGI 118
           V   Q    H+ L+ + ++ N++N    RE+    +  + D D + V++S  G +F  G+
Sbjct: 159 VVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAAD-DSKLVLLSAVGSVFCCGL 217

Query: 119 DLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDL 178
           D +     +     DD  R S  + + I  +  TF   +   KP+I AV+G  IG G  +
Sbjct: 218 DFIYFIRRLT----DDRKRESTKMAEAIRNFVNTFIQFK---KPIIVAVNGPAIGLGASI 270

Query: 179 VTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEAL 238
           +  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+  + RK+ A EA 
Sbjct: 271 LPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGAS-ANEMLLSGRKLTAQEAC 329

Query: 239 GSGLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTK 276
           G GLVS+VF       +  + +  E++S +PV ++ +K
Sbjct: 330 GKGLVSQVFWPGTFTQEVMVRI-KELASCNPVVLEESK 366


>gi|221136753 chromodomain protein, Y chromosome-like isoform d
           [Homo sapiens]
          Length = 412

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 62/218 (28%), Positives = 108/218 (49%), Gaps = 11/218 (5%)

Query: 60  VTSAQKHVLHVQLN-RPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGI 118
           V   Q    H+ L+ + ++ N++N    RE+    +  + D D + V++S  G +F  G+
Sbjct: 159 VVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAAD-DSKLVLLSAVGSVFCCGL 217

Query: 119 DLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDL 178
           D +     +     DD  R S  + + I  +  TF   +   KP+I AV+G  IG G  +
Sbjct: 218 DFIYFIRRLT----DDRKRESTKMAEAIRNFVNTFIQFK---KPIIVAVNGPAIGLGASI 270

Query: 179 VTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEAL 238
           +  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+  + RK+ A EA 
Sbjct: 271 LPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGAS-ANEMLLSGRKLTAQEAC 329

Query: 239 GSGLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTK 276
           G GLVS+VF       +  + +  E++S +PV ++ +K
Sbjct: 330 GKGLVSQVFWPGTFTQEVMVRI-KELASCNPVVLEESK 366


>gi|4757966 Y chromosome chromodomain protein 1, telomeric isoform b
           [Homo sapiens]
          Length = 554

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 62/227 (27%), Positives = 104/227 (45%), Gaps = 18/227 (7%)

Query: 54  SYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKM 113
           +Y  + V         V   R  ++NA+N    +E+V   N  + D D + V+ S AG +
Sbjct: 282 TYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAAD-DSKLVLFSAAGSV 340

Query: 114 FTAGIDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIG 173
           F  G+D       +   +       S  + D I  +  TF   +   KP++ +V+G  IG
Sbjct: 341 FCCGLDFGYFVKHLRNNRNT----ASLEMVDTIKNFVNTFIQFK---KPIVVSVNGPAIG 393

Query: 174 GGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMM 233
            G  ++  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+    RK+ 
Sbjct: 394 LGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKAS-ANEMLIAGRKLT 452

Query: 234 ADEALGSGLVSRVFP----DKEVMLDAALALAAEISSKSPVAVQSTK 276
           A EA   GLVS+VF      +EVM+        E++S +P+ ++  K
Sbjct: 453 AREACAKGLVSQVFLTGTFTQEVMIQ-----IKELASYNPIVLEECK 494


>gi|25453481 Y chromosome chromodomain protein 1, telomeric isoform
           a [Homo sapiens]
          Length = 540

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 62/227 (27%), Positives = 104/227 (45%), Gaps = 18/227 (7%)

Query: 54  SYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKM 113
           +Y  + V         V   R  ++NA+N    +E+V   N  + D D + V+ S AG +
Sbjct: 282 TYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAAD-DSKLVLFSAAGSV 340

Query: 114 FTAGIDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIG 173
           F  G+D       +   +       S  + D I  +  TF   +   KP++ +V+G  IG
Sbjct: 341 FCCGLDFGYFVKHLRNNRNT----ASLEMVDTIKNFVNTFIQFK---KPIVVSVNGPAIG 393

Query: 174 GGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMM 233
            G  ++  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+    RK+ 
Sbjct: 394 LGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKAS-ANEMLIAGRKLT 452

Query: 234 ADEALGSGLVSRVFP----DKEVMLDAALALAAEISSKSPVAVQSTK 276
           A EA   GLVS+VF      +EVM+        E++S +P+ ++  K
Sbjct: 453 AREACAKGLVSQVFLTGTFTQEVMIQ-----IKELASYNPIVLEECK 494


>gi|51538581 chromodomain protein, Y-linked, 1B isoform b [Homo
           sapiens]
          Length = 554

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 62/227 (27%), Positives = 104/227 (45%), Gaps = 18/227 (7%)

Query: 54  SYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKM 113
           +Y  + V         V   R  ++NA+N    +E+V   N  + D D + V+ S AG +
Sbjct: 282 TYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAAD-DSKLVLFSAAGSV 340

Query: 114 FTAGIDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIG 173
           F  G+D       +   +       S  + D I  +  TF   +   KP++ +V+G  IG
Sbjct: 341 FCCGLDFGYFVKHLRNNRNT----ASLEMVDTIKNFVNTFIQFK---KPIVVSVNGPAIG 393

Query: 174 GGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMM 233
            G  ++  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+    RK+ 
Sbjct: 394 LGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKAS-ANEMLIAGRKLT 452

Query: 234 ADEALGSGLVSRVFP----DKEVMLDAALALAAEISSKSPVAVQSTK 276
           A EA   GLVS+VF      +EVM+        E++S +P+ ++  K
Sbjct: 453 AREACAKGLVSQVFLTGTFTQEVMIQ-----IKELASYNPIVLEECK 494


>gi|51538573 chromodomain protein, Y-linked, 1B isoform a [Homo
           sapiens]
          Length = 540

 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 62/227 (27%), Positives = 104/227 (45%), Gaps = 18/227 (7%)

Query: 54  SYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKM 113
           +Y  + V         V   R  ++NA+N    +E+V   N  + D D + V+ S AG +
Sbjct: 282 TYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAAD-DSKLVLFSAAGSV 340

Query: 114 FTAGIDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIG 173
           F  G+D       +   +       S  + D I  +  TF   +   KP++ +V+G  IG
Sbjct: 341 FCCGLDFGYFVKHLRNNRNT----ASLEMVDTIKNFVNTFIQFK---KPIVVSVNGPAIG 393

Query: 174 GGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMM 233
            G  ++  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+    RK+ 
Sbjct: 394 LGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKAS-ANEMLIAGRKLT 452

Query: 234 ADEALGSGLVSRVFP----DKEVMLDAALALAAEISSKSPVAVQSTK 276
           A EA   GLVS+VF      +EVM+        E++S +P+ ++  K
Sbjct: 453 AREACAKGLVSQVFLTGTFTQEVMIQ-----IKELASYNPIVLEECK 494


>gi|49355787 Y chromosome chromodomain protein 2B [Homo sapiens]
          Length = 541

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 57/194 (29%), Positives = 91/194 (46%), Gaps = 9/194 (4%)

Query: 54  SYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKM 113
           +Y  + V         V   R  ++NA+N    +EMV   N  + D D + V+ S AG +
Sbjct: 283 TYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEMVNALNSAAAD-DSKLVLFSAAGSV 341

Query: 114 FTAGIDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIG 173
           F  G+D        ++   +D    S  + D I  +  TF   +   KP++ +V+G  IG
Sbjct: 342 FCCGLDF----GYFVRHLRNDRNTASLEMVDTIKNFVNTFIQFK---KPIVVSVNGPAIG 394

Query: 174 GGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMM 233
            G  ++  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+    RK+ 
Sbjct: 395 LGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKAS-ANEMLIAGRKLT 453

Query: 234 ADEALGSGLVSRVF 247
           A EA   GLVS+VF
Sbjct: 454 AREACAKGLVSQVF 467


>gi|4757968 Y chromosome chromodomain protein 2A [Homo sapiens]
          Length = 541

 Score = 80.5 bits (197), Expect = 2e-15
 Identities = 57/194 (29%), Positives = 91/194 (46%), Gaps = 9/194 (4%)

Query: 54  SYESLRVTSAQKHVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKM 113
           +Y  + V         V   R  ++NA+N    +EMV   N  + D D + V+ S AG +
Sbjct: 283 TYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEMVNALNSAAAD-DSKLVLFSAAGSV 341

Query: 114 FTAGIDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIG 173
           F  G+D        ++   +D    S  + D I  +  TF   +   KP++ +V+G  IG
Sbjct: 342 FCCGLDF----GYFVRHLRNDRNTASLEMVDTIKNFVNTFIQFK---KPIVVSVNGPAIG 394

Query: 174 GGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMM 233
            G  ++  CD+ +  + A+FQ      G + D  +    PK++G  S  NE+    RK+ 
Sbjct: 395 LGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKAS-ANEMLIAGRKLT 453

Query: 234 ADEALGSGLVSRVF 247
           A EA   GLVS+VF
Sbjct: 454 AREACAKGLVSQVF 467


>gi|116235487 chromodomain protein, Y-like 2 [Homo sapiens]
          Length = 506

 Score = 79.0 bits (193), Expect = 6e-15
 Identities = 62/238 (26%), Positives = 116/238 (48%), Gaps = 20/238 (8%)

Query: 60  VTSAQKHVLHVQLN-RPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGI 118
           V   ++   H+ L+ + +  NA+     +E+       + D D + +++S  G +F +G+
Sbjct: 253 VVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATD-DSKLLLLSAVGSVFCSGL 311

Query: 119 DLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDL 178
           D   +   +   +  +  RI+  +RD +  + +         KP++ A++G  +G G  +
Sbjct: 312 DYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQF-------KKPIVVAINGPALGLGASI 364

Query: 179 VTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEAL 238
           +  CDI + ++ A+FQ     + L     +    P+++G  +L NE+ F  RK+ A EA 
Sbjct: 365 LPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILG-VALANEMLFCGRKLTAQEAC 423

Query: 239 GSGLVSRVF----PDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLN 292
             GLVS+VF      +EVML        E++S S V ++ +K  L+ S   SV E +N
Sbjct: 424 SRGLVSQVFWPTTFSQEVML-----RVKEMASCSAVVLEESKC-LVRSFLKSVLEDVN 475


>gi|20127408 mitochondrial trifunctional protein, alpha subunit
           precursor [Homo sapiens]
          Length = 763

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 57/182 (31%), Positives = 93/182 (51%), Gaps = 17/182 (9%)

Query: 70  VQLNRPNKR-NAMNKVFWREMVECFNKISRDADCR-AVVISGAGKMFTAGIDL-MDMASD 126
           V++N PN + N ++K    E  E  N+I      R AV+IS     F AG D+ M  A  
Sbjct: 52  VRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACK 111

Query: 127 ILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRY 186
            LQ    +V ++S   + I+ +       +E+  KP++AA++G C+GGG+++  +C  R 
Sbjct: 112 TLQ----EVTQLSQEAQRIVEK-------LEKSTKPIVAAINGSCLGGGLEVAISCQYRI 160

Query: 187 CAQD--AFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVS 244
             +D        EV +G     G  QRLPK++G  + + ++  T R + AD A   GLV 
Sbjct: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAAL-DMMLTGRSIRADRAKKMGLVD 219

Query: 245 RV 246
           ++
Sbjct: 220 QL 221


>gi|45643119 peroxisomal D3,D2-enoyl-CoA isomerase isoform 1 [Homo
           sapiens]
          Length = 364

 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 72/279 (25%), Positives = 125/279 (44%), Gaps = 17/279 (6%)

Query: 15  LTRRLTGSNYPGLSISLRLTGSSAQEEASGVALG-EAPDHSYESLRVTSAQKHVLHVQLN 73
           L +     NY  L  SL    S + E +S V  G +     +E+L VTS +  +  +  N
Sbjct: 72  LPKEAARQNYVDLVSSL----SPSLESSSQVEPGTDRKSTGFETLVVTS-EDGITKIMFN 126

Query: 74  RPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASDILQPKGD 133
           RP K+NA+N   + E++      S+D D    V++G G  +++G DL +     + P G 
Sbjct: 127 RPKKKNAINTEMYHEIMRALKAASKD-DSIITVLTGNGDYYSSGNDLTNFTD--IPPGG- 182

Query: 134 DVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFF 193
               +    ++     +E        PKP+IA V+G  +G  V L+   D  Y +  A F
Sbjct: 183 ----VEEKAKNNAVLLREFVGCFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYASDRATF 238

Query: 194 QVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPDKEVM 253
                 +G + +  +    PK++ + +   E+    +K+ A EA   GLV+ VFPD    
Sbjct: 239 HTPFSHLGQSPEGCSSYTFPKIM-SPAKATEMLIFGKKLTAGEACAQGLVTEVFPDSTFQ 297

Query: 254 LDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLN 292
            +    L A  +   P A++ +K  ++  R+     ++N
Sbjct: 298 KEVWTRLKA-FAKLPPNALRISK-EVIRKREREKLHAVN 334


>gi|31542718 enoyl Coenzyme A hydratase domain containing 3 [Homo
           sapiens]
          Length = 303

 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 60/223 (26%), Positives = 104/223 (46%), Gaps = 21/223 (9%)

Query: 59  RVTSAQK--HVLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTA 116
           R TSA++   + ++ L+ P KRN ++    + +       +   D + ++IS  G +F++
Sbjct: 46  RPTSARQLDGIRNIVLSNPKKRNTLSLAMLKSLQSDILHDADSNDLKVIIISAEGPVFSS 105

Query: 117 GIDLMDMASDILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGV 176
           G DL ++  +    +G D      Y  ++     +    I   P PVIA V+G     G 
Sbjct: 106 GHDLKELTEE----QGRD------YHAEVFQTCSKVMMHIRNHPVPVIAMVNGLATAAGC 155

Query: 177 DLVTACDIRYCAQDAFFQVKEVDVGL---AADVGTLQRLPKVIGNQSLVNELAFTARKMM 233
            LV +CDI   +  + F    V+VGL      V   + +P+      +  E+ FT   + 
Sbjct: 156 QLVASCDIAVASDKSSFATPGVNVGLFCSTPGVALARAVPR-----KVALEMLFTGEPIS 210

Query: 234 ADEALGSGLVSRVFPDKEVMLDAALALAAEISSKSPVAVQSTK 276
           A EAL  GL+S+V P+ E+  +  + +A +I+S S   V   K
Sbjct: 211 AQEALLHGLLSKVVPEAELQ-EETMRIARKIASLSRPVVSLGK 252


>gi|68989263 enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A
           dehydrogenase [Homo sapiens]
          Length = 723

 Score = 72.4 bits (176), Expect = 5e-13
 Identities = 61/240 (25%), Positives = 108/240 (45%), Gaps = 21/240 (8%)

Query: 79  NAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASDILQPKGDDVARI 138
           NA++    R++ E   K   D   +A+VI GA   F+AG D+   ++             
Sbjct: 22  NAISTTLLRDIKEGLQKAVIDHTIKAIVICGAEGKFSAGADIRGFSAP------------ 69

Query: 139 SWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFFQVKEV 198
               R          + I+R  KPV+AA+ G   GGG++L   C  R    +A   + EV
Sbjct: 70  ----RTFGLTLGHVVDEIQRNEKPVVAAIQGMAFGGGLELALGCHYRIAHAEAQVGLPEV 125

Query: 199 DVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPDKEVMLDAAL 258
            +GL       Q LP++ G  + + +L  + R+++ADEAL  G++ +V     V  + A+
Sbjct: 126 TLGLLPGARGTQLLPRLTGVPAAL-DLITSGRRILADEALKLGILDKVVNSDPV--EEAI 182

Query: 259 ALAAEISSK--SPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQDLVKSVQATTE 316
             A  +S +      + +  +  L + D   +E+L  +   +   L  +  V++VQA  +
Sbjct: 183 RFAQRVSDQPLESRRLCNKPIQSLPNMDSIFSEALLKMRRQHPGCLAQEACVRAVQAAVQ 242


>gi|157694516 enoyl Coenzyme A hydratase domain containing 1 isoform
           1 [Homo sapiens]
          Length = 301

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 54/222 (24%), Positives = 107/222 (48%), Gaps = 13/222 (5%)

Query: 72  LNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASDILQPK 131
           LN P++ NA + V   +++E   ++    + + +++ GA   F++G DL  + S  L   
Sbjct: 63  LNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKS--LGTP 120

Query: 132 GDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDA 191
            D +A +  ++++ +TR+        R P   +A V G  +GGG +  TACD R    ++
Sbjct: 121 EDGMA-VCMFMQNTLTRFM-------RLPLISVALVQGWALGGGAEFTTACDFRLMTPES 172

Query: 192 FFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVF--PD 249
             +    ++G+    G   RL ++IG++  +  L+  A K+ +  AL  G+V  V    D
Sbjct: 173 KIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS-GALKLDSKNALNIGMVEEVLQSSD 231

Query: 250 KEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESL 291
           +   L+ A     +     P  +++ K ++   R+  + E+L
Sbjct: 232 ETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEAL 273


>gi|213417737 enoyl Coenzyme A hydratase domain containing 1 isoform
           5 [Homo sapiens]
          Length = 307

 Score = 72.0 bits (175), Expect = 7e-13
 Identities = 54/222 (24%), Positives = 107/222 (48%), Gaps = 13/222 (5%)

Query: 72  LNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASDILQPK 131
           LN P++ NA + V   +++E   ++    + + +++ GA   F++G DL  + S  L   
Sbjct: 69  LNNPSRMNAFSGVMMLQLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKS--LGTP 126

Query: 132 GDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDA 191
            D +A +  ++++ +TR+        R P   +A V G  +GGG +  TACD R    ++
Sbjct: 127 EDGMA-VCMFMQNTLTRFM-------RLPLISVALVQGWALGGGAEFTTACDFRLMTPES 178

Query: 192 FFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVF--PD 249
             +    ++G+    G   RL ++IG++  +  L+  A K+ +  AL  G+V  V    D
Sbjct: 179 KIRFVHKEMGIIPSWGGTTRLVEIIGSRQALKVLS-GALKLDSKNALNIGMVEEVLQSSD 237

Query: 250 KEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESL 291
           +   L+ A     +     P  +++ K ++   R+  + E+L
Sbjct: 238 ETKSLEEAQEWLKQFIQGPPEVIRALKKSVCSGRELYLEEAL 279


>gi|37594469 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 2
           [Homo sapiens]
          Length = 338

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 62/260 (23%), Positives = 110/260 (42%), Gaps = 19/260 (7%)

Query: 70  VQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAG-KMFTAGIDLMDMASDIL 128
           + LNRP   NA+     R++     K  +D +   ++I GAG K F AG D+  ++    
Sbjct: 49  ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS---- 104

Query: 129 QPKGDDVARISWYLRDIITRYQETFN-VIERCPKPVIAAVHGGCIGGGVDLVTACDIRYC 187
                +  +    +  +  R +   N  +  C KP +A +HG  +GGGV L      R  
Sbjct: 105 -----EAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVA 159

Query: 188 AQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSR-V 246
            +   F + E  +GL  DVG    LP++ G   L   LA T  ++   +   +G+ +  V
Sbjct: 160 TEKCLFAMPETAIGLFPDVGGGYFLPRLQG--KLGYFLALTGFRLKGRDVYRAGIATHFV 217

Query: 247 FPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQD 306
             +K  ML+  L     ++ KSP       V   Y  +  +    +++   +M  + +  
Sbjct: 218 DSEKLAMLEEDL-----LALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCF 272

Query: 307 LVKSVQATTENKELKTVTFS 326
              +V+   EN +    +F+
Sbjct: 273 SANTVEEIIENLQQDGSSFA 292


>gi|37594471 3-hydroxyisobutyryl-Coenzyme A hydrolase isoform 1
           [Homo sapiens]
          Length = 386

 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 62/260 (23%), Positives = 110/260 (42%), Gaps = 19/260 (7%)

Query: 70  VQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVISGAG-KMFTAGIDLMDMASDIL 128
           + LNRP   NA+     R++     K  +D +   ++I GAG K F AG D+  ++    
Sbjct: 49  ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDIRVIS---- 104

Query: 129 QPKGDDVARISWYLRDIITRYQETFN-VIERCPKPVIAAVHGGCIGGGVDLVTACDIRYC 187
                +  +    +  +  R +   N  +  C KP +A +HG  +GGGV L      R  
Sbjct: 105 -----EAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVA 159

Query: 188 AQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSR-V 246
            +   F + E  +GL  DVG    LP++ G   L   LA T  ++   +   +G+ +  V
Sbjct: 160 TEKCLFAMPETAIGLFPDVGGGYFLPRLQG--KLGYFLALTGFRLKGRDVYRAGIATHFV 217

Query: 247 FPDKEVMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSMLQTQD 306
             +K  ML+  L     ++ KSP       V   Y  +  +    +++   +M  + +  
Sbjct: 218 DSEKLAMLEEDL-----LALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCF 272

Query: 307 LVKSVQATTENKELKTVTFS 326
              +V+   EN +    +F+
Sbjct: 273 SANTVEEIIENLQQDGSSFA 292


>gi|150378541 enoyl Coenzyme A hydratase domain containing 2 [Homo
           sapiens]
          Length = 261

 Score = 66.2 bits (160), Expect = 4e-11
 Identities = 65/261 (24%), Positives = 101/261 (38%), Gaps = 47/261 (18%)

Query: 67  VLHVQLNRPNKRNAMNKVFWREMVECFNKISRDADCRAVVI-SGAGKMFTAGIDLMDMAS 125
           +  + +NRP+ RNA+  VF  E++E   ++  D   R ++  SG   +F AG DL +   
Sbjct: 42  ITEILMNRPSARNALGNVFVSELLETLAQLREDRQVRVLLFRSGVKGVFCAGADLKEREQ 101

Query: 126 DILQPKGDDVARISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIR 185
                 G  V R+   + DI                                        
Sbjct: 102 MSEAEVGVFVQRLRGLMNDI---------------------------------------- 121

Query: 186 YCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSR 245
             A  A   + E   GL    G  QRLP+ +G  +L  EL FT R++   EA   GLV+ 
Sbjct: 122 --ASSAVMGLIETTRGLLPGAGGTQRLPRCLG-VALAKELIFTGRRLSGTEAHVLGLVNH 178

Query: 246 VFPDKE---VMLDAALALAAEISSKSPVAVQSTKVNLLYSRDHSVAESLNYVASWNMSML 302
                E        A ALA EI  ++P+AV+  KV +    +  +A  +          +
Sbjct: 179 AVAQNEEGDAAYQRARALAQEILPQAPIAVRLGKVAIDRGTEVDIASGMAIEGMCYAQNI 238

Query: 303 QTQDLVKSVQATTENKELKTV 323
            T+D ++ + A  E +  K V
Sbjct: 239 PTRDRLEGMAAFREKRTPKFV 259


>gi|157694520 enoyl Coenzyme A hydratase domain containing 1 isoform
           3 [Homo sapiens]
          Length = 226

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 48/206 (23%), Positives = 98/206 (47%), Gaps = 13/206 (6%)

Query: 88  EMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASDILQPKGDDVARISWYLRDIIT 147
           +++E   ++    + + +++ GA   F++G DL  + S  L    D +A +  ++++ +T
Sbjct: 4   QLLEKVIELENWTEGKGLIVRGAKNTFSSGSDLNAVKS--LGTPEDGMA-VCMFMQNTLT 60

Query: 148 RYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVG 207
           R+        R P   +A V G  +GGG +  TACD R    ++  +    ++G+    G
Sbjct: 61  RFM-------RLPLISVALVQGWALGGGAEFTTACDFRLMTPESKIRFVHKEMGIIPSWG 113

Query: 208 TLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVF--PDKEVMLDAALALAAEIS 265
              RL ++IG++  +  L+  A K+ +  AL  G+V  V    D+   L+ A     +  
Sbjct: 114 GTTRLVEIIGSRQALKVLS-GALKLDSKNALNIGMVEEVLQSSDETKSLEEAQEWLKQFI 172

Query: 266 SKSPVAVQSTKVNLLYSRDHSVAESL 291
              P  +++ K ++   R+  + E+L
Sbjct: 173 QGPPEVIRALKKSVCSGRELYLEEAL 198


>gi|62530384 dodecenoyl-Coenzyme A delta isomerase precursor [Homo
           sapiens]
          Length = 302

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 48/186 (25%), Positives = 85/186 (45%), Gaps = 15/186 (8%)

Query: 79  NAMNKVFWREMVECFNKISRDADCRAVVI-SGAGKMFTAGIDLMDMASDILQPKGDDVAR 137
           N+++  F  E+V    K+  D   R V++ S    +F+AG+DL +M        G   A 
Sbjct: 68  NSLSLEFLTELVISLEKLENDKSFRGVILTSDRPGVFSAGLDLTEMC-------GRSPAH 120

Query: 138 ISWYLRDIITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFFQV-- 195
            + Y + +    QE +  + +    +++A++G C  GG  +   CD R  A +  + +  
Sbjct: 121 YAGYWKAV----QELWLRLYQSNLVLVSAINGACPAGGCLVALTCDYRILADNPRYCIGL 176

Query: 196 KEVDVGLAADVGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPDKEVMLD 255
            E  +G+ A       L   IG+++    L        A EAL  G+V +V P+++V   
Sbjct: 177 NETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPA-EALQVGIVDQVVPEEQVQST 235

Query: 256 AALALA 261
           A  A+A
Sbjct: 236 ALSAIA 241


>gi|45643121 peroxisomal D3,D2-enoyl-CoA isomerase isoform 2 [Homo
           sapiens]
          Length = 227

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 49/207 (23%), Positives = 91/207 (43%), Gaps = 11/207 (5%)

Query: 86  WREMVECFNKISRDADCRAVVISGAGKMFTAGIDLMDMASDILQPKGDDVARISWYLRDI 145
           + E++      S+D D    V++G G  +++G DL +     + P G     +    ++ 
Sbjct: 2   YHEIMRALKAASKD-DSIITVLTGNGDYYSSGNDLTNFTD--IPPGG-----VEEKAKNN 53

Query: 146 ITRYQETFNVIERCPKPVIAAVHGGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAAD 205
               +E        PKP+IA V+G  +G  V L+   D  Y +  A F      +G + +
Sbjct: 54  AVLLREFVGCFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPE 113

Query: 206 VGTLQRLPKVIGNQSLVNELAFTARKMMADEALGSGLVSRVFPDKEVMLDAALALAAEIS 265
             +    PK++ + +   E+    +K+ A EA   GLV+ VFPD     +    L A  +
Sbjct: 114 GCSSYTFPKIM-SPAKATEMLIFGKKLTAGEACAQGLVTEVFPDSTFQKEVWTRLKA-FA 171

Query: 266 SKSPVAVQSTKVNLLYSRDHSVAESLN 292
              P A++ +K  ++  R+     ++N
Sbjct: 172 KLPPNALRISK-EVIRKREREKLHAVN 197


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 29.3 bits (64), Expect = 5.0
 Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 2/40 (5%)

Query: 268 SPVAVQSTKVNLLYSRDHSVAESL-NYVASWNMSMLQTQD 306
           +PVAV  T++ +  ++ HS+ E + NY   WN  M+ T+D
Sbjct: 134 NPVAVIITQLTIT-TKVHSLLEGISNYFTKWNKHMMDTRD 172


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 29.3 bits (64), Expect = 5.0
 Identities = 15/40 (37%), Positives = 25/40 (62%), Gaps = 2/40 (5%)

Query: 268 SPVAVQSTKVNLLYSRDHSVAESL-NYVASWNMSMLQTQD 306
           +PVAV  T++ +  ++ HS+ E + NY   WN  M+ T+D
Sbjct: 134 NPVAVIITQLTIT-TKVHSLLEGISNYFTKWNKHMMDTRD 172


>gi|18860857 menin isoform 1 [Homo sapiens]
          Length = 615

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 20/117 (17%)

Query: 122 DMASDILQPKGDDVARISWYLRDIITRYQETFNV-------------IERCPKPVIAAVH 168
           D A  +  P G+  A ++W+ +    R  +T N                RC + +  A  
Sbjct: 185 DHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFM 244

Query: 169 GGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNEL 225
              I   +DL T             Q+++  + L  D+G L+R P  +GN + + EL
Sbjct: 245 VCAINPSIDLHTD-------SLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEEL 294


>gi|18860855 menin isoform 1 [Homo sapiens]
          Length = 615

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 20/117 (17%)

Query: 122 DMASDILQPKGDDVARISWYLRDIITRYQETFNV-------------IERCPKPVIAAVH 168
           D A  +  P G+  A ++W+ +    R  +T N                RC + +  A  
Sbjct: 185 DHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFM 244

Query: 169 GGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNEL 225
              I   +DL T             Q+++  + L  D+G L+R P  +GN + + EL
Sbjct: 245 VCAINPSIDLHTD-------SLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEEL 294


>gi|18860851 menin isoform 1 [Homo sapiens]
          Length = 615

 Score = 28.9 bits (63), Expect = 6.6
 Identities = 27/117 (23%), Positives = 46/117 (39%), Gaps = 20/117 (17%)

Query: 122 DMASDILQPKGDDVARISWYLRDIITRYQETFNV-------------IERCPKPVIAAVH 168
           D A  +  P G+  A ++W+ +    R  +T N                RC + +  A  
Sbjct: 185 DHAWVVFGPNGEQTAEVTWHGKGNEDRRGQTVNAGVAERSWLYLKGSYMRCDRKMEVAFM 244

Query: 169 GGCIGGGVDLVTACDIRYCAQDAFFQVKEVDVGLAADVGTLQRLPKVIGNQSLVNEL 225
              I   +DL T             Q+++  + L  D+G L+R P  +GN + + EL
Sbjct: 245 VCAINPSIDLHTD-------SLELLQLQQKLLWLLYDLGHLERYPMALGNLADLEEL 294


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.131    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,334,798
Number of Sequences: 37866
Number of extensions: 400903
Number of successful extensions: 1040
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 980
Number of HSP's gapped (non-prelim): 41
length of query: 328
length of database: 18,247,518
effective HSP length: 103
effective length of query: 225
effective length of database: 14,347,320
effective search space: 3228147000
effective search space used: 3228147000
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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