Search of human proteins with 70778918

Search of human proteins with 70778918

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
sapiens]
         (946 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo ...  1896   0.0  
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [...   681   0.0  
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]       624   e-178
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]        493   e-139
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor...   490   e-138
gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor...   419   e-117
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ...   374   e-103
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]   364   e-100
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ...    59   3e-08
gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subun...    59   3e-08
gi|218505703 von Willebrand factor A domain containing 3A [Homo ...    56   1e-07
gi|54112390 calcium channel, voltage-dependent, alpha 2/delta su...    47   6e-05
gi|210147462 von Willebrand factor A domain containing 5B1 [Homo...    47   6e-05
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su...    40   0.013
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su...    40   0.013
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo...    37   0.067
gi|73765544 phosphatase and tensin homolog [Homo sapiens]              33   1.6  
gi|31377562 HAUS augmin-like complex, subunit 6 [Homo sapiens]         32   2.8  
gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]          32   2.8  
gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a...    32   2.8  
gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b...    32   2.8  
gi|118918435 von Willebrand factor A domain containing 3B [Homo ...    32   3.7  
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [...    31   4.8  
gi|41352705 kinesin family member 3C [Homo sapiens]                    31   4.8  
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                 31   6.2  
gi|239735519 SET binding factor 1 [Homo sapiens]                       30   8.2  
gi|197313748 SET domain containing 2 [Homo sapiens]                    30   8.2  
gi|48255968 UDP-glucose pyrophosphorylase 2 isoform b [Homo sapi...    30   8.2  
gi|48255966 UDP-glucose pyrophosphorylase 2 isoform a [Homo sapi...    30   8.2  

>gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
           sapiens]
          Length = 946

 Score = 1896 bits (4912), Expect = 0.0
 Identities = 946/946 (100%), Positives = 946/946 (100%)

Query: 1   MKRLTCFFICFFLSEVSGFEIPINGLSEFVDYEDLVELAPGKFQLVAENRRYQRSLPGES 60
           MKRLTCFFICFFLSEVSGFEIPINGLSEFVDYEDLVELAPGKFQLVAENRRYQRSLPGES
Sbjct: 1   MKRLTCFFICFFLSEVSGFEIPINGLSEFVDYEDLVELAPGKFQLVAENRRYQRSLPGES 60

Query: 61  EEMMEEVDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFS 120
           EEMMEEVDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFS
Sbjct: 61  EEMMEEVDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFS 120

Query: 121 MTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFE 180
           MTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFE
Sbjct: 121 MTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFE 180

Query: 181 LHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHFDGVPVI 240
           LHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHFDGVPVI
Sbjct: 181 LHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHFDGVPVI 240

Query: 241 SKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFA 300
           SKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFA
Sbjct: 241 SKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFA 300

Query: 301 PDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRN 360
           PDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRN
Sbjct: 301 PDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRN 360

Query: 361 DLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVS 420
           DLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVS
Sbjct: 361 DLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVS 420

Query: 421 DGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQ 480
           DGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQ
Sbjct: 421 DGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQ 480

Query: 481 DTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQ 540
           DTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQ
Sbjct: 481 DTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQ 540

Query: 541 IESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAP 600
           IESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAP
Sbjct: 541 IESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAP 600

Query: 601 TAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSCCSGALYYGSK 660
           TAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSCCSGALYYGSK
Sbjct: 601 TAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSCCSGALYYGSK 660

Query: 661 VVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYLPKSQKNICFNI 720
           VVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYLPKSQKNICFNI
Sbjct: 661 VVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYLPKSQKNICFNI 720

Query: 721 DSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLSTYFGKLGFYFQSEDIKIEISTETI 780
           DSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLSTYFGKLGFYFQSEDIKIEISTETI
Sbjct: 721 DSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLSTYFGKLGFYFQSEDIKIEISTETI 780

Query: 781 TLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNVD 840
           TLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNVD
Sbjct: 781 TLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNVD 840

Query: 841 FLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIITRGL 900
           FLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIITRGL
Sbjct: 841 FLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIITRGL 900

Query: 901 QKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP 946
           QKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP
Sbjct: 901 QKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLYSFLKRP 946


>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
           [Homo sapiens]
          Length = 890

 Score =  681 bits (1756), Expect = 0.0
 Identities = 354/881 (40%), Positives = 537/881 (60%), Gaps = 43/881 (4%)

Query: 70  VTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFR 129
           + +YS K+ S +TSR A  ++  + VN +   + V FDV++PK AFI+NF++T+DG T+ 
Sbjct: 43  IEVYSTKINSKVTSRFAHNVVTMRAVNRADTAKEVSFDVELPKTAFITNFTLTIDGVTYP 102

Query: 130 SSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWR 189
            ++KEK V +  Y +A ++GKTAGLV++S   +E F   VNV  G+KV FEL Y+E+  R
Sbjct: 103 GNVKEKEVAKKQYEKAVSQGKTAGLVKASGRKLEKFTVSVNVAAGSKVTFELTYEELLKR 162

Query: 190 KLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGH--FDGVPVISKGQQKA 247
             G YE  + +QP +L KH E++V + EPQG+  L    +F  +         S   +K 
Sbjct: 163 HKGKYEMYLKVQPKQLVKHFEIEVDIFEPQGISMLDAEASFITNDLLGSALTKSFSGKKG 222

Query: 248 HVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAPDNLDPI 307
           HVSFKP++ QQR CP C ++ ++G+  + YDV RE   G +++ NGYFVHFFAP  L  +
Sbjct: 223 HVSFKPSLDQQRSCPTCTDSLLNGDFTITYDVNRESP-GNVQIVNGYFVHFFAPQGLPVV 281

Query: 308 PKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLISATK 367
           PKN+ FVID+SGSM G K++QT EA+  IL+D++ ED+ + I F+ ++ TW+  L+ AT 
Sbjct: 282 PKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQATP 341

Query: 368 TQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPTVG 427
             + +A+ +++ ++  G TNIN+ LLR I +LN+A     +   S S++I+++DGD  VG
Sbjct: 342 ENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGDANVG 401

Query: 428 ELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQLK 487
           E +  KIQ+NV+  I     L++LG G +++Y+FL+ ++ ENHG A+RIY + D   QL+
Sbjct: 402 ESRPEKIQENVRNAIGGKFPLYNLGFGNNLNYNFLENMALENHGFARRIYEDSDADLQLQ 461

Query: 488 KFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQIESVITA 547
            FY +V+ PLL  V+  YP  ++ D+TQN + +++ GSEIVVAG+     ++  ++ +  
Sbjct: 462 GFYEEVANPLLTGVEMEYPENAILDLTQNTYQHFYDGSEIVVAGRLVDEDMNSFKADVKG 521

Query: 548 TSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAAKRR 607
             A   L       M +++  L +  +   ++  +LWAYLTI QLL +R  A     K  
Sbjct: 522 HGATNDLTFTEEVDMKEMEKALQERDYIFGNYIERLWAYLTIEQLLEKRKNAH-GEEKEN 580

Query: 608 ITRSILQMSLDHHIVTPLTSLVI----ENEAGDERMLADAPPQDPSCCSGALYYGSKVVP 663
           +T   L +SL +H VTPLTS+V+    +NE  DER +AD P +D                
Sbjct: 581 LTARALDLSLKYHFVTPLTSMVVTKPEDNE--DERAIADKPGEDA--------------- 623

Query: 664 DSTPSWANPSPTPVISMLAQGSQVLESTPPPH--VMRVENDPHFIIYLPKSQKNICFNID 721
           ++TP       +P +S L        S  PP      V+ DPHFII +P+    +CFNID
Sbjct: 624 EATPV------SPAMSYLT-------SYQPPQNPYYYVDGDPHFIIQIPEKDDALCFNID 670

Query: 722 SEPGKILNLVSDPESGIVVNGQLVGAKK--PNNGKLSTYFGKLGFYFQSEDIKIEISTET 779
             PG +L L+ D  +G+ VNGQ+ G K+  P++    TYFGKLG      D ++E++TE 
Sbjct: 671 EAPGTVLRLIQDAVTGLTVNGQITGDKRGSPDSKTRKTYFGKLGIANAQMDFQVEVTTEK 730

Query: 780 ITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNV 839
           ITL + +   + SW DT  VT   + + + ++ +V ++    ++F V+LH+VWKKHPV+ 
Sbjct: 731 ITLWNRAVPSTFSWLDTVTVTQDGLSMMINRKNMV-VSFGDGVTFVVVLHQVWKKHPVHR 789

Query: 840 DFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIITRG 899
           DFLG Y+  +++ S + HGL+GQF Q     + + RPG DP KP+A++ VK  +LI+TRG
Sbjct: 790 DFLGFYVVDSHRMSAQTHGLLGQFFQPFDFKVSDIRPGSDPTKPDATLVVKNHQLIVTRG 849

Query: 900 LQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLY 940
            QKDYR D   GT V CWFVHN+G+G IDG + DY VP L+
Sbjct: 850 SQKDYRKDASIGTKVVCWFVHNNGEGLIDGVHTDYIVPNLF 890


>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
          Length = 911

 Score =  624 bits (1609), Expect = e-178
 Identities = 350/895 (39%), Positives = 518/895 (57%), Gaps = 25/895 (2%)

Query: 54  RSLPGESEEMMEE-VDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPK 112
           RS   E  + ++  VD V + S KV   +TSR A  ++ S+VVN + + + V FD++IPK
Sbjct: 34  RSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPK 93

Query: 113 GAFISNFSMTVDGKTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVL 172
            AFIS+F++T DG  F   IK+K      Y +A   G+ AGLVR+S   ME F   + V 
Sbjct: 94  TAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVN 153

Query: 173 PGAKVQFELHYQEVKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEG 232
           P +KV F+L Y+EV  R    YE  I ++P +L  H E+DV + EPQG+  L    +F  
Sbjct: 154 PQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLP 213

Query: 233 HFDGVPVISKG--QQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEV 290
                  I K    +K HV F+PTV+QQ+ CP C  + ++G   V YDV R+ K  +L V
Sbjct: 214 KELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRD-KICDLLV 272

Query: 291 FNGYFVHFFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVID 350
            N +F HFFAP NL  + KN++FVID+SGSM G K+KQT EA+  IL D++  D+F ++ 
Sbjct: 273 ANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVL 332

Query: 351 FNQNIRTWRNDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDP 410
           F   +++W+  L+ A++  +  A+ ++        TN+N  LLR I ILN+         
Sbjct: 333 FGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELS 392

Query: 411 NSVSLIILVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENH 470
           N  S++I+++DGDPT G    S+I KNV+  I+    L++LG G +VD++FL+ +S EN+
Sbjct: 393 NHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENN 452

Query: 471 GIAQRIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVA 530
           G AQRIY + D + QL+ FY+QV+ PLL +V   YP  +V  +TQN+   Y+ GSEIVVA
Sbjct: 453 GRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVA 512

Query: 531 GKFDPAKLDQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTIN 590
           G+    K    ++ + A     +  +  L   ++++  L +  H   +   +LWAYLTI 
Sbjct: 513 GRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQ 572

Query: 591 QLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSC 650
           +LLA+R +      +  ++   LQMSLD+  VTPLTS+ I       R +AD     P+ 
Sbjct: 573 ELLAKR-MKVDREERANLSSQALQMSLDYGFVTPLTSMSI-------RGMADQDGLKPTI 624

Query: 651 CSGALYYGSKVVPDSTP-SWANPSPTPVISMLAQGSQVLESTP---PPHVMRVENDPHFI 706
                    K   DS P     P  T V+S L        S     P  V  V+ DPHFI
Sbjct: 625 --------DKPSEDSPPLEMLGPRRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFI 676

Query: 707 IYLPKSQKNICFNIDSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLS-TYFGKLGFY 765
           I++P+ +  +CFNI+ EPG IL+LV DP +G  VNGQL+G K  + G+   TYFG+LG  
Sbjct: 677 IHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIA 736

Query: 766 FQSEDIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFS 825
             + D ++E++ + ITL+ G      SW D A +    V +++ K++ + +++D   +F 
Sbjct: 737 NPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFE 796

Query: 826 VLLHRVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEA 885
           V+LHRVWK   V+ DFLG Y+  +++ S + HGL+GQF       + +  PG DP KP+A
Sbjct: 797 VVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDA 856

Query: 886 SMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDYFVPQLY 940
           +M V+ ++L +TRGLQKDY  D   G +V+CWF+HN+G G IDG Y DY VP ++
Sbjct: 857 TMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF 911


>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
          Length = 930

 Score =  493 bits (1268), Expect = e-139
 Identities = 311/922 (33%), Positives = 489/922 (53%), Gaps = 90/922 (9%)

Query: 66  EVDQVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDG 125
           E + + +YS  V S ++SR A T++ S+VVN +   Q   F +++PK AFI+NFSM +DG
Sbjct: 29  EKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIIDG 88

Query: 126 KTFRSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQE 185
            T+   IKEK   +A Y+ A AKGK+AGLV+++  +ME F+  V+V P AK+ FEL Y+E
Sbjct: 89  MTYPGIIKEKAEAQAQYSAAVAKGKSAGLVKATGRNMEQFQVSVSVAPNAKITFELVYEE 148

Query: 186 VKWRKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTF-EGHFDGVPVISKGQ 244
           +  R+LG YE  + ++P +L KHL++D+ + EPQG+ FL    TF            + +
Sbjct: 149 LLKRRLGVYELLLKVRPQQLVKHLQMDIHIFEPQGISFLETESTFMTNQLVDALTTWQNK 208

Query: 245 QKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAPDNL 304
            KAH+ FKPT++QQ+  P  +ET +DG L++ YDV R    G +++ NGYFVH+FAP+ L
Sbjct: 209 TKAHIRFKPTLSQQQKSPEQQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAPEGL 268

Query: 305 DPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLIS 364
             +PKN++FVID SGSM G K++QT EA+  ILDDL   D F++I F+     WR  L+ 
Sbjct: 269 TTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVP 328

Query: 365 ATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDP 424
           A+   V  A+ +   IQ  GGTNIN+A+L A+ +L+ +N    L   SVSLIIL++DGDP
Sbjct: 329 ASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDP 388

Query: 425 TVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSS 484
           TVGE     IQ NV+E +    SLF LG GFDV Y FL++L+ +N G+A+RI+ + D++ 
Sbjct: 389 TVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSAL 448

Query: 485 QLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQIESV 544
           QL+ FY +V+ PLL  V F YP  +V +VTQNNF   F GSE+VVAGK      D + + 
Sbjct: 449 QLQDFYQEVANPLLTAVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVLTAT 508

Query: 545 ITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAA 604
           ++       +  +T + + + +      K+   +F  +LWAYLTI QLL E++++ + A 
Sbjct: 509 VSGKLPTQNITFQTESSVAEQEAEFQSPKYIFHNFMERLWAYLTIQQLL-EQTVSASDAD 567

Query: 605 KRRITRSILQMSLDHHIVTPLTSLVIENEAGDER-MLADAPPQDPS----CCSGALYY-- 657
           ++ +    L +SL +  VTPLTS+V+      E+  +A+ P +  S      SG+ ++  
Sbjct: 568 QQALRNQALNLSLAYSFVTPLTSMVVTKPDDQEQSQVAEKPMEGESRNRNVHSGSTFFKY 627

Query: 658 ---GSKVV---------------------------------------PDSTPSWANPSPT 675
              G+K+                                        P   P  A   P 
Sbjct: 628 YLQGAKIPKPEASFSPRRGWNRQAGAAGSRMNFRPGVLSSRQLGLPGPPDVPDHAAYHPF 687

Query: 676 PVISMLAQGSQVLESTPPPHVMRVEN-----------------DPHFIIYLP-KSQKNIC 717
             +++L   +    S P P V RV N                  P  I+ LP +S + +C
Sbjct: 688 RRLAILPASAPPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPGQSVERLC 747

Query: 718 FNIDSEPGKILNLVSDPESGIVVNGQLVGAKKPNNGKLSTYFGKLGFYFQSEDIKIEIST 777
            +     G + NL+SDPE G+ V GQ    K          F  +   F++  + +  S 
Sbjct: 748 VDPRHRQGPV-NLLSDPEQGVEVTGQYEREK--------AGFSWIEVTFKNPLVWVHASP 798

Query: 778 ETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRVWKKHPV 837
           E + ++    + +  W +T       +++++ K  ++ ++   +++  +L    W     
Sbjct: 799 EHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLF---WDGRG- 854

Query: 838 NVDFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPEASMEVKGQKLIIT 897
             + L + +  T++FS    G +GQF QE    ++      D  +   ++ V+G     T
Sbjct: 855 --EGLRLLLRDTDRFSSHVGGTLGQFYQEV---LWGSPAASDDGR--RTLRVQGNDHSAT 907

Query: 898 RGLQKDYRTDLVFGTDVTCWFV 919
           R  + DY+     G +++CW V
Sbjct: 908 RERRLDYQEGPP-GVEISCWSV 928


>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 1 [Homo sapiens]
          Length = 956

 Score =  490 bits (1261), Expect = e-138
 Identities = 303/895 (33%), Positives = 474/895 (52%), Gaps = 61/895 (6%)

Query: 75  YKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSIKE 134
           + V+STI SR A T +  +++N + + Q++ F +QIP  AFI+NF+M +  K ++  I E
Sbjct: 54  FSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITE 113

Query: 135 KTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWRKLGSY 194
           +        + +    T     +     E FR    +    K  F L Y+E+  R+LG Y
Sbjct: 114 REKKSGDRVKEKRNKTTE---ENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKY 170

Query: 195 EHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHV--------PDTFEGHFDGVP----VISK 242
           EH I ++P +L+  L VDV ++E  G+  L V          +  G  D  P    VI++
Sbjct: 171 EHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQ 230

Query: 243 GQQKAHVSFKPTVAQQ-RICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAP 301
            +  A++ FKPTV QQ RI  N     + G+ ++ YDV RE+  G+++V NGYFVH+FAP
Sbjct: 231 NETFANIIFKPTVVQQARIAQN----GILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAP 286

Query: 302 DNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRND 361
            +L P+PKN++FV+D S SM G K++QT +A+ TIL DLR +D FS+I F+  I+ W++ 
Sbjct: 287 KDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDH 346

Query: 362 LISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSD 421
           LIS T   + D K YI  + P+GGT+IN AL RAI +LN+      +   SVSLI+ ++D
Sbjct: 347 LISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTD 406

Query: 422 GDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQD 481
           G PTVGE    KI  N +E  +  + +F++G+G DVD+  L++LS EN G+ +R++  +D
Sbjct: 407 GKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEED 466

Query: 482 TSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQI 541
             SQL  FY+++ TPLL +++ +YP +SV   T+  F NYF GSEI++AGK    KLD +
Sbjct: 467 AGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHL 526

Query: 542 ESVITATSANTQLVLET---LAQMDDLQDFLSK-----DKHADPDFTRKLWAYLTINQLL 593
              +TA+++   ++L+T   +      +D         D   D +   +LW+YLT  +LL
Sbjct: 527 HVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELL 586

Query: 594 AERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPSCCSG 653
           +    +     K R+ +    +++ +  +TP TS+ +         L +A     +    
Sbjct: 587 SSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAA---- 642

Query: 654 ALYYGSKVVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYLPKSQ 713
               G + V  S    A   P P++    Q    +  T       V+ DPHF++  P S+
Sbjct: 643 ---MGPEPVVQSVRG-AGTQPGPLLKKPYQPRIKISKT------SVDGDPHFVVDFPLSR 692

Query: 714 KNICFNIDSEPGKILNLVSD-PESGIVVNGQLVGAKKPNNG--KLSTYFGKLGFYF-QSE 769
             +CFNID +PG IL LVSD  +SG+ VNG+L+GA  P NG  K  TY   +     + E
Sbjct: 693 LTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILINKPE 752

Query: 770 DIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLH 829
              +EI+   + L  G     L  + +  V +  +++SV     VT+T+   ++F +L+H
Sbjct: 753 RSYLEITPSRVILD-GGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFVILIH 811

Query: 830 RVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQE----------PKIHIFNERPGKD 879
              K  P     LG YI  +   S   HGL+GQF+ +          P  ++ +    + 
Sbjct: 812 LYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPLLLQV 871

Query: 880 PEKPEASMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDY 934
            E PEA + VKG ++ +    +K Y  +      + CWF  N+    IDG YKDY
Sbjct: 872 GEGPEAVLTVKGHQVPVVWKQRKIYNGE----EQIDCWFARNNAAKLIDGEYKDY 922


>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 2 [Homo sapiens]
          Length = 742

 Score =  419 bits (1077), Expect = e-117
 Identities = 251/719 (34%), Positives = 390/719 (54%), Gaps = 46/719 (6%)

Query: 239 VISKGQQKAHVSFKPTVAQQ-RICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVH 297
           VI++ +  A++ FKPTV QQ RI  N     + G+ ++ YDV RE+  G+++V NGYFVH
Sbjct: 13  VINQNETFANIIFKPTVVQQARIAQN----GILGDFIIRYDVNREQSIGDIQVLNGYFVH 68

Query: 298 FFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRT 357
           +FAP +L P+PKN++FV+D S SM G K++QT +A+ TIL DLR +D FS+I F+  I+ 
Sbjct: 69  YFAPKDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKV 128

Query: 358 WRNDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLII 417
           W++ LIS T   + D K YI  + P+GGT+IN AL RAI +LN+      +   SVSLI+
Sbjct: 129 WKDHLISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIV 188

Query: 418 LVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIY 477
            ++DG PTVGE    KI  N +E  +  + +F++G+G DVD+  L++LS EN G+ +R++
Sbjct: 189 FLTDGKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVH 248

Query: 478 GNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAK 537
             +D  SQL  FY+++ TPLL +++ +YP +SV   T+  F NYF GSEI++AGK    K
Sbjct: 249 EEEDAGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRK 308

Query: 538 LDQIESVITATSANTQLVLET---LAQMDDLQDFLSK-----DKHADPDFTRKLWAYLTI 589
           LD +   +TA+++   ++L+T   +      +D         D   D +   +LW+YLT 
Sbjct: 309 LDHLHVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTT 368

Query: 590 NQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQDPS 649
            +LL+    +     K R+ +    +++ +  +TP TS+ +         L +A     +
Sbjct: 369 KELLSSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSMKLRGPVPRMDGLEEAHGMSAA 428

Query: 650 CCSGALYYGSKVVPDSTPSWANPSPTPVISMLAQGSQVLESTPPPHVMRVENDPHFIIYL 709
                   G + V  S    A   P P++    Q    +  T       V+ DPHF++  
Sbjct: 429 -------MGPEPVVQSVRG-AGTQPGPLLKKPYQPRIKISKT------SVDGDPHFVVDF 474

Query: 710 PKSQKNICFNIDSEPGKILNLVSD-PESGIVVNGQLVGAKKPNNG--KLSTYFGKLGFYF 766
           P S+  +CFNID +PG IL LVSD  +SG+ VNG+L+GA  P NG  K  TY   +    
Sbjct: 475 PLSRLTVCFNIDGQPGDILRLVSDHRDSGVTVNGELIGAPAPPNGHKKQRTYLRTITILI 534

Query: 767 -QSEDIKIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFS 825
            + E   +EI+   + L  G     L  + +  V +  +++SV     VT+T+   ++F 
Sbjct: 535 NKPERSYLEITPSRVILD-GGDRLVLPCNQSVVVGSWGLEVSVSANANVTVTIQGSIAFV 593

Query: 826 VLLHRVWKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQE----------PKIHIFNER 875
           +L+H   K  P     LG YI  +   S   HGL+GQF+ +          P  ++ +  
Sbjct: 594 ILIHLYKKPAPFQRHHLGFYIANSEGLSSNCHGLLGQFLNQDARLTEDPAGPSQNLTHPL 653

Query: 876 PGKDPEKPEASMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGHYKDY 934
             +  E PEA + VKG ++ +    +K Y  +      + CWF  N+    IDG YKDY
Sbjct: 654 LLQVGEGPEAVLTVKGHQVPVVWKQRKIYNGE----EQIDCWFARNNAAKLIDGEYKDY 708


>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
           isoform 3 [Homo sapiens]
          Length = 702

 Score =  374 bits (960), Expect = e-103
 Identities = 210/575 (36%), Positives = 331/575 (57%), Gaps = 28/575 (4%)

Query: 75  YKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSIKE 134
           + V+STI SR A T +  +++N + + Q++ F +QIP  AFI+NF+M +  K ++  I E
Sbjct: 54  FSVKSTIISRYAFTTVSCRMLNRASEDQDIEFQMQIPAAAFITNFTMLIGDKVYQGEITE 113

Query: 135 KTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKWRKLGSY 194
           +        + +    T     +     E FR    +    K  F L Y+E+  R+LG Y
Sbjct: 114 REKKSGDRVKEKRNKTTE---ENGEKGTEIFRASAVIPSKDKAAFFLSYEELLQRRLGKY 170

Query: 195 EHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHV--------PDTFEGHFDGVP----VISK 242
           EH I ++P +L+  L VDV ++E  G+  L V          +  G  D  P    VI++
Sbjct: 171 EHSISVRPQQLSGRLSVDVNILESAGIASLEVLPLHNSRQRGSGRGEDDSGPPPSTVINQ 230

Query: 243 GQQKAHVSFKPTVAQQ-RICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVHFFAP 301
            +  A++ FKPTV QQ RI  N     + G+ ++ YDV RE+  G+++V NGYFVH+FAP
Sbjct: 231 NETFANIIFKPTVVQQARIAQN----GILGDFIIRYDVNREQSIGDIQVLNGYFVHYFAP 286

Query: 302 DNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRND 361
            +L P+PKN++FV+D S SM G K++QT +A+ TIL DLR +D FS+I F+  I+ W++ 
Sbjct: 287 KDLPPLPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDH 346

Query: 362 LISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSD 421
           LIS T   + D K YI  + P+GGT+IN AL RAI +LN+      +   SVSLI+ ++D
Sbjct: 347 LISVTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTD 406

Query: 422 GDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQD 481
           G PTVGE    KI  N +E  +  + +F++G+G DVD+  L++LS EN G+ +R++  +D
Sbjct: 407 GKPTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLSLENCGLTRRVHEEED 466

Query: 482 TSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQI 541
             SQL  FY+++ TPLL +++ +YP +SV   T+  F NYF GSEI++AGK    KLD +
Sbjct: 467 AGSQLIGFYDEIRTPLLSDIRIDYPPSSVVQATKTLFPNYFNGSEIIIAGKLVDRKLDHL 526

Query: 542 ESVITATSANTQLVLET---LAQMDDLQDFLSK-----DKHADPDFTRKLWAYLTINQLL 593
              +TA+++   ++L+T   +      +D         D   D +   +LW+YLT  +LL
Sbjct: 527 HVEVTASNSKKFIILKTDVPVRPQKAGKDVTGSPRPGGDGEGDTNHIERLWSYLTTKELL 586

Query: 594 AERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSL 628
           +    +     K R+ +    +++ +  +TP TS+
Sbjct: 587 SSWLQSDDEPEKERLRQRAQALAVSYRFLTPFTSM 621


>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
          Length = 1313

 Score =  364 bits (934), Expect = e-100
 Identities = 224/649 (34%), Positives = 349/649 (53%), Gaps = 30/649 (4%)

Query: 69  QVTLYSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTF 128
           ++ + SY ++ST+ SR A T++ S + N   +    +FD+ +P  AFISNF+MT++ K +
Sbjct: 34  KLLMTSYSMRSTVVSRYAHTLVTSVLFNPHAEAHEAIFDLDLPHLAFISNFTMTINNKVY 93

Query: 129 RSSIKEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEVNVLPGAKVQFELHYQEVKW 188
            + +KEK   + +Y +A  +GKTA  V     + E FR   ++  G +V F L Y+E+  
Sbjct: 94  IAEVKEKHQAKKIYEEAHQQGKTAAHVGIRDRESEKFRISTSLAAGTEVTFSLAYEELLQ 153

Query: 189 RKLGSYEHRIYLQPGRLAKHLEVDVWVIEPQGLRFLHVPDTFEGHF---------DGVPV 239
           R  G Y+  + L+PG+L K L ++V V E  G+ ++H+P    G           D  P 
Sbjct: 154 RHQGQYQLVVSLRPGQLVKRLSIEVTVSERTGISYVHIPPLRTGRLRTNAHASEVDSPPS 213

Query: 240 --ISKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYDVKREEKAGELEVFNGYFVH 297
             I +G+    +++ PT+  Q    +   + +  + +V YDV  E+  G++++++ YF+H
Sbjct: 214 TRIERGETCVRITYCPTLQDQ---SSISGSGIMADFLVQYDVVMEDIIGDVQIYDDYFIH 270

Query: 298 FFAPDNLDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRT 357
           +FAP  L P+ KN++FVIDVS SM+G KM+QT  AM  IL DL+A D+F++I F+  +  
Sbjct: 271 YFAPRGLPPMEKNVVFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISFSDTVNV 330

Query: 358 WR-NDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPN--SVS 414
           W+    I AT   V  AK Y+  ++  G T++N ALL A  +LN +N      P+   + 
Sbjct: 331 WKAGGSIQATIQNVHSAKDYLHCMEADGWTDVNSALLAAASVLNHSNQEPGRGPSVGRIP 390

Query: 415 LIILVSDGDPTVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQ 474
           LII ++DG+PT G    S I  NV++ +   +SLFSL  G D D+  L+RLS EN GIA+
Sbjct: 391 LIIFLTDGEPTAGVTTPSVILSNVRQALGHRVSLFSLAFGDDADFTLLRRLSLENRGIAR 450

Query: 475 RIYGNQDTSSQLKKFYNQVSTPLLRNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFD 534
           RIY + D + QLK  Y ++S PLL +V+ NY    V       F NYFGGSE+VVAG+  
Sbjct: 451 RIYEDTDAALQLKGLYEEISMPLLADVRLNYLGGLVGASPWAVFPNYFGGSELVVAGQVQ 510

Query: 535 PAKLDQIESVITATSANTQLVL--ETLAQMDDLQDFLSKDKHADPD---FTRKLWAYLTI 589
           P K  ++   + A     QL++   +    ++ Q          P+   F R+LWAY+TI
Sbjct: 511 PGK-QELGIHLAARGPKDQLLVAHHSEGATNNSQKAFGCPGEPAPNVAHFIRRLWAYVTI 569

Query: 590 NQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVI--ENEAGDE--RMLADAPP 645
            +LL     A     +  +   +L +SL+++ VTPLTSLV+    +A +E  R  + +  
Sbjct: 570 GELLDAHFQARDTTTRHLLAAKVLNLSLEYNFVTPLTSLVMVQPKQASEETRRQTSTSAG 629

Query: 646 QDPSCCSGALYYG---SKVVPDSTPSWANPSPTPVISMLAQGSQVLEST 691
            D    S +  +G   S   P   P   +P   PV       S    ST
Sbjct: 630 PDTIMPSSSSRHGLGVSTAQPALVPKVISPKSRPVKPKFYLSSTTTAST 678



 Score =  102 bits (255), Expect = 1e-21
 Identities = 84/285 (29%), Positives = 132/285 (46%), Gaps = 32/285 (11%)

Query: 664  DSTPSWANPSPTPVI----SMLAQGSQV-LESTPPPHVMR----VENDPHFIIYLPKSQK 714
            D +P+W   S   +     SM +QGS V L     P +      V+ DPHF+I +P S++
Sbjct: 1036 DGSPNWDGNSEEILGGAGGSMESQGSSVGLAKGTLPSIFTFSSSVDGDPHFVIQIPHSEE 1095

Query: 715  NICFNIDSEPGKILNLVSDPESGIVVNGQLVGA--KKPNNGKLSTYFGKLGFYF-QSEDI 771
             ICF ++  PG +L L+ DP++G+ V+G+L+GA  +  +  +  TYF  +     +    
Sbjct: 1096 KICFTLNGHPGDLLQLIEDPKAGLHVSGKLLGAPPRPGHKDQTRTYFQIITVTTDKPRAY 1155

Query: 772  KIEISTETITLSHGSSTFSLSWSDTAQVTNQRVQISVKKEKVVTITLDKEMSFSVLLHRV 831
             I IS  +I+L  G  T  LSW   A +   ++++ V     +T+ L   + F VL HR 
Sbjct: 1156 TITISRSSISL-RGEGTLRLSWDQPALLKRPQLELYVAAAARLTLRLGPYLEFLVLRHRY 1214

Query: 832  WKKHPVNVDFLGIYIPPTNKFSPKAHGLIGQFMQEPKIHIFNERPG------KDPEKPEA 885
                 + +  LG Y+   +  SP A GLIGQF Q   I +     G        P+ P  
Sbjct: 1215 RHPSTLQLPHLGFYVANGSGLSPSARGLIGQF-QHADIRLVTGPMGPCLRRHHGPDVP-- 1271

Query: 886  SMEVKGQKLIITRGLQKDYRTDLVFGTDVTCWFVHNSGKGFIDGH 930
                    +I+ + L KD  +  +     +CW V  S    + GH
Sbjct: 1272 --------VILGKRLLKD--SPRLLPRWASCWLVKRSHVELLLGH 1306


>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
           subunit [Homo sapiens]
          Length = 1091

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 48/195 (24%), Positives = 96/195 (49%), Gaps = 13/195 (6%)

Query: 308 PKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIR----TWRNDLI 363
           PK+++ ++DVSGSM G+++    + + +ILD L  +D F++I +N+ +          L+
Sbjct: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313

Query: 364 SATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGD 423
            A +T     + +++K+   G   ++ AL  A  IL++ N+ G     S   I+L++DG 
Sbjct: 314 QADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICS-QAIMLITDGA 372

Query: 424 PTVGELKLSKIQKNVKENIQD-NISLFSLGMGFDVDY-DFLKRLSNENHGIAQRIYGNQD 481
               +   +K       N  D  + +F+  +G +  + D LK ++  N G   +I    D
Sbjct: 373 VDTYDTIFAKY------NWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLAD 426

Query: 482 TSSQLKKFYNQVSTP 496
               + ++ + +S P
Sbjct: 427 VQENVMEYLHVLSRP 441


>gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subunit
           [Homo sapiens]
          Length = 1137

 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 54/202 (26%), Positives = 95/202 (47%), Gaps = 19/202 (9%)

Query: 308 PKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIR----TWRNDLI 363
           PK+I+ ++DVSGSM G++M      + TILD L   D  ++I +N  +      ++  L+
Sbjct: 289 PKDIVILVDVSGSMKGLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIEPCFKGILV 348

Query: 364 SATKTQVADAKRYIEKIQPSGGTNINEALLRAIFIL---NEANNLGLLDPNSVSLIILVS 420
            A +      K  +E++   G   +++AL  A  IL    EA    L +      I+L+S
Sbjct: 349 QADRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQFQEAKQGSLCN----QAIMLIS 404

Query: 421 DGDPTVGELKLSKIQKNVKENIQD-NISLFSLGMGFDVDY-DFLKRLSNENHGIAQRIYG 478
           DG     E    K       N  D  + +F+  +G +V + D +K ++  N G   +I  
Sbjct: 405 DGAVEDYEPVFEKY------NWPDCKVRVFTYLIGREVSFADRMKWIACNNKGYYTQIST 458

Query: 479 NQDTSSQLKKFYNQVSTPLLRN 500
             DT   + ++ + +S P++ N
Sbjct: 459 LADTQENVMEYLHVLSRPMVIN 480


>gi|218505703 von Willebrand factor A domain containing 3A [Homo
            sapiens]
          Length = 1184

 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 43/167 (25%), Positives = 82/167 (49%), Gaps = 15/167 (8%)

Query: 307  IPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLR-AEDHFSVIDFNQNIRTWRNDLISA 365
            +   +  ++D SGSM     +   E +  I + LR   D F+++ F ++ ++W++ L+  
Sbjct: 956  LESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVET 1015

Query: 366  TKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDP- 424
            T     +A +++  +Q  G T+I +ALL+A F  ++   L LL           +DG P 
Sbjct: 1016 TDAACHEAMQWVTHLQAQGSTSILQALLKA-FSFHDLEGLYLL-----------TDGKPD 1063

Query: 425  TVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHG 471
            T   L L+++QK ++E     +   SL        +FL++L++   G
Sbjct: 1064 TSCSLVLNEVQK-LREKRDVKVHTISLNCSDRAAVEFLRKLASFTGG 1109



 Score = 38.1 bits (87), Expect = 0.039
 Identities = 23/96 (23%), Positives = 53/96 (55%), Gaps = 2/96 (2%)

Query: 311 ILFVIDVSGSMWGVKMKQTVEAMKTILDD-LRAEDHFSVIDFNQNIRTWRNDLISATKTQ 369
           +  +IDVS    G + ++  + + +++D+ L  ++   V+ F  N  +   D +  + + 
Sbjct: 171 VSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSAST 230

Query: 370 VADAKRYIEKIQPSGGTNINEALLRAIFILNEANNL 405
           + + K +++ +QP GG+N+ +A L+ IF L   ++L
Sbjct: 231 LQELKLWVKTLQPDGGSNLLQA-LKKIFTLKGLDSL 265


>gi|54112390 calcium channel, voltage-dependent, alpha 2/delta
           subunit 1 [Homo sapiens]
          Length = 1091

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 71/354 (20%), Positives = 142/354 (40%), Gaps = 41/354 (11%)

Query: 308 PKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIR--TWRNDLISA 365
           PK++L ++DVSGS+ G+ +K    ++  +L+ L  +D  +V  FN N +  +    L+ A
Sbjct: 251 PKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQDVSCFQHLVQA 310

Query: 366 TKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPT 425
                   K  +  I   G T+  +      F   +  N  +   N   +I+L +DG   
Sbjct: 311 NVRNKKVLKDAVNNITAKGITDYKKGF---SFAFEQLLNYNVSRANCNKIIMLFTDG--- 364

Query: 426 VGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQ 485
            GE +  +I     ++ +  +  FS+G   + D   ++ ++ EN G    I         
Sbjct: 365 -GEERAQEIFNKYNKDKKVRVFTFSVGQ-HNYDRGPIQWMACENKGYYYEIPSIGAIRIN 422

Query: 486 LKKFYNQVSTPLL------RNVQFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKL- 538
            +++ + +  P++      + VQ+   +    ++             +V+ G      + 
Sbjct: 423 TQEYLDVLGRPMVLAGDKAKQVQWTNVYLDALEL------------GLVITGTLPVFNIT 470

Query: 539 DQIESVITATSANTQLVLETLAQMDDLQDFLSKDKHADPDFT----RKLWAYLTINQLLA 594
            Q E+    T+   QL+L  +     L+D     K   P FT       +A      +L 
Sbjct: 471 GQFEN---KTNLKNQLILGVMGVDVSLEDI----KRLTPRFTLCPNGYYFAIDPNGYVLL 523

Query: 595 ERSLAP-TAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDERMLADAPPQD 647
             +L P    ++  +T   L   L++ I   + + +I+ E+G++        QD
Sbjct: 524 HPNLQPKNPKSQEPVTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQD 577


>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
           sapiens]
          Length = 1215

 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 50/223 (22%), Positives = 104/223 (46%), Gaps = 16/223 (7%)

Query: 312 LFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLISATKTQVA 371
           +F+ID S SM G+ M +  +AM   L  L     F++I F    ++      + ++  +A
Sbjct: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422

Query: 372 DAKRYIEKIQPS-GGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDPTVGELK 430
            A   I++++   GGTNI   L    +++ +  + G        L+ +++DG        
Sbjct: 423 MACDDIQRMKADMGGTNILSPLK---WVIRQPVHRG-----HPRLLFVITDGAVN----N 470

Query: 431 LSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHGIAQRIYGNQDTSSQLKKFY 490
             K+ + V+ N   +   +S G+G +V +  +K L++ + G A+ +   +    ++ K  
Sbjct: 471 TGKVLELVR-NHAFSTRCYSFGIGPNVCHRLVKGLASVSEGSAELLMEGERLQPKMVKSL 529

Query: 491 NQVSTPLLRN--VQFNYPHTSVTDVTQNNFHNYFGGSEIVVAG 531
            +   P+L +  V++ +P T+   V+  +  + F G  +V  G
Sbjct: 530 KKAMAPVLSDVTVEWIFPETTEVLVSPVSASSLFPGERLVGYG 572


>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta
           subunit 2 isoform b [Homo sapiens]
          Length = 1143

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 5/117 (4%)

Query: 308 PKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIR--TWRNDLISA 365
           PK+++ ++DVSGS+ G+ +K    ++  +LD L  +D+ +V  FN+  +  +    L+ A
Sbjct: 289 PKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQA 348

Query: 366 TKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDG 422
                   K  ++ +   G T          +  ++  N  +   N   +I++ +DG
Sbjct: 349 NVRNKKVFKEAVQGMVAKGTTGYKAGF---EYAFDQLQNSNITRANCNKMIMMFTDG 402


>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta
           subunit 2 isoform a [Homo sapiens]
          Length = 1145

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 26/117 (22%), Positives = 55/117 (47%), Gaps = 5/117 (4%)

Query: 308 PKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIR--TWRNDLISA 365
           PK+++ ++DVSGS+ G+ +K    ++  +LD L  +D+ +V  FN+  +  +    L+ A
Sbjct: 289 PKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSDDDYVNVASFNEKAQPVSCFTHLVQA 348

Query: 366 TKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDG 422
                   K  ++ +   G T          +  ++  N  +   N   +I++ +DG
Sbjct: 349 NVRNKKVFKEAVQGMVAKGTTGYKAGF---EYAFDQLQNSNITRANCNKMIMMFTDG 402


>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
           sapiens]
          Length = 1724

 Score = 37.4 bits (85), Expect = 0.067
 Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 9/172 (5%)

Query: 19  FEIPINGLSEF--VDYEDLVELAP--GKFQLVAENRRYQRSLPGESEEMMEEV--DQVTL 72
           F +P + + +F   D+ +L E  P    F  V + +         ++  +++   + V L
Sbjct: 564 FSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQLPDAKTSSSTKAGLQDASGNLVPL 623

Query: 73  YSYKVQSTITSRMATTMIQSKVVNNSPQPQNVVFDVQIPKGAFISNFSMTVDGKTFRSSI 132
               ++  I   +A  ++     N S  P    +   +   A +  F   ++GK     I
Sbjct: 624 EDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIVGEI 683

Query: 133 KEKTVGRALYAQARAKGKTAGLVRSSALDMENFRTEV-NVLPGAKVQFELHY 183
           KEK   +  Y +A  +G  A L+   A D+  F   V N+ P AKV  ++ Y
Sbjct: 684 KEKEEAQQEYLEAVTQGHGAYLMSQDAPDV--FTVSVGNLPPKAKVLIKITY 733


>gi|73765544 phosphatase and tensin homolog [Homo sapiens]
          Length = 403

 Score = 32.7 bits (73), Expect = 1.6
 Identities = 35/116 (30%), Positives = 51/116 (43%), Gaps = 11/116 (9%)

Query: 525 SEIVVAGKFDPAKLDQIESVITATSANTQLVLETLAQMDDLQDFLSKDK---HADPDFTR 581
           SE V  G     ++D I S+  A +    LVL TL + D   D  +KDK   +  P+F  
Sbjct: 287 SEKVENGSLCDQEIDSICSIERADNDKEYLVL-TLTKND--LDKANKDKANRYFSPNFKV 343

Query: 582 KLWAYLTINQLLAERSLAPTAAAKRRITRSILQMSLDHHIVTPLTSLVIENEAGDE 637
           KL+   T+     E    P A++   +T  +     DH+  +  T    ENE  DE
Sbjct: 344 KLYFTKTV-----EEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDE 394


>gi|31377562 HAUS augmin-like complex, subunit 6 [Homo sapiens]
          Length = 955

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 11/137 (8%)

Query: 502 QFNYPHTSVTDVTQNNFHNYFGGSEIVVAGKFDPAKLDQ---IESVITAT-SANTQLVLE 557
           +F   ++ ++DV +N   + FGGS  + A K DP + +Q   +E V  A  S + QL   
Sbjct: 501 EFEVENSPLSDVAKNTESSAFGGS--LPAKKSDPFQKEQDHLVEEVARAVLSDSPQLSEG 558

Query: 558 TLAQMDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTA-AAKRRITRSILQMS 616
              ++++L D L     ++P  TR        N +   RS    A   +   T+  +QM 
Sbjct: 559 KEIKLEELIDSLG----SNPFLTRNQIPRTPENLITEIRSSWRKAIEMEENRTKEPIQMD 614

Query: 617 LDHHIVTPLTSLVIENE 633
            +H  V P +  V+ N+
Sbjct: 615 AEHREVLPESLPVLHNQ 631


>gi|210032509 hypothetical protein LOC100130302 [Homo sapiens]
          Length = 887

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 15/38 (39%), Positives = 23/38 (60%), Gaps = 4/38 (10%)

Query: 847 PPTNKFSPKAHGLIGQFMQEPKIHIFNERPGKDPEKPE 884
           PP  ++SP+A    G+ +QE    I+ E  GK+PE P+
Sbjct: 23  PPRRRYSPRA----GKTLQEKLYDIYVEECGKEPEDPQ 56


>gi|112363100 SLIT-ROBO Rho GTPase activating protein 2 isoform a
           [Homo sapiens]
          Length = 1071

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 18/86 (20%)

Query: 562 MDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAAKRRITRSILQMSLDHHI 621
           + DLQDF  K    + D++R L       + LAER LA T + K +      Q   D ++
Sbjct: 46  LQDLQDFFRKKAEIEMDYSRNL-------EKLAERFLAKTRSTKDQ------QFKKDQNV 92

Query: 622 VTP-----LTSLVIENEAGDERMLAD 642
           ++P     L    ++ E+ D   L+D
Sbjct: 93  LSPVNCWNLLLNQVKRESRDHTTLSD 118


>gi|112363096 SLIT-ROBO Rho GTPase activating protein 2 isoform b
           [Homo sapiens]
          Length = 836

 Score = 32.0 bits (71), Expect = 2.8
 Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 18/86 (20%)

Query: 562 MDDLQDFLSKDKHADPDFTRKLWAYLTINQLLAERSLAPTAAAKRRITRSILQMSLDHHI 621
           + DLQDF  K    + D++R L       + LAER LA T + K +      Q   D ++
Sbjct: 46  LQDLQDFFRKKAEIEMDYSRNL-------EKLAERFLAKTRSTKDQ------QFKKDQNV 92

Query: 622 VTP-----LTSLVIENEAGDERMLAD 642
           ++P     L    ++ E+ D   L+D
Sbjct: 93  LSPVNCWNLLLNQVKRESRDHTTLSD 118


>gi|118918435 von Willebrand factor A domain containing 3B [Homo
           sapiens]
          Length = 1294

 Score = 31.6 bits (70), Expect = 3.7
 Identities = 21/85 (24%), Positives = 36/85 (42%)

Query: 311 ILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIRTWRNDLISATKTQV 370
           I  +ID S SM         + ++ I + L+ +  F+ + F+     WR  L    +  +
Sbjct: 509 IYILIDTSHSMKSKLDLVKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNL 568

Query: 371 ADAKRYIEKIQPSGGTNINEALLRA 395
             A+ +I  I+    TN   AL  A
Sbjct: 569 EQAQSWIRDIKIGSSTNTLSALKTA 593


>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal
           [Homo sapiens]
          Length = 1937

 Score = 31.2 bits (69), Expect = 4.8
 Identities = 33/163 (20%), Positives = 68/163 (41%), Gaps = 13/163 (7%)

Query: 693 PPHVMRVENDPHFIIYLPKSQKNICFNIDSEPGKILNL--VSDPESGIVVNGQLVGAKKP 750
           PPH+  + ++ +  +   +  ++I    +S  GK +N   V    + I V G+    KK 
Sbjct: 154 PPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNTKRVIQYFATIAVTGE---KKKD 210

Query: 751 NNGKLSTYFGKLGFYFQSEDIKIEISTETITLSHGSST-----FSLSWSDTAQVTNQRVQ 805
            +GK+    G L     S +  +E      T+ + +S+       + +  T ++ +  ++
Sbjct: 211 ESGKMQ---GTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFIRIHFGTTGKLASADIE 267

Query: 806 ISVKKEKVVTITLDKEMSFSVLLHRVWKKHPVNVDFLGIYIPP 848
             + ++  VT  L  E S+ +       K P  ++ L I   P
Sbjct: 268 TYLLEKSRVTFQLKAERSYHIFYQITSNKKPDLIEMLLITTNP 310


>gi|41352705 kinesin family member 3C [Homo sapiens]
          Length = 793

 Score = 31.2 bits (69), Expect = 4.8
 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 2/48 (4%)

Query: 695 HVMRVENDPHFI--IYLPKSQKNICFNIDSEPGKILNLVSDPESGIVV 740
           H+ R +N  + +   YL   Q+ I   +  EPGK L L  +PE+G+ +
Sbjct: 130 HISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYI 177


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score = 30.8 bits (68), Expect = 6.2
 Identities = 31/143 (21%), Positives = 66/143 (46%), Gaps = 9/143 (6%)

Query: 304 LDPIPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRA---EDHFSVIDFNQNIRT-WR 359
           L P+P +++F++D S S+     +Q  + + +++        +    +  ++ + +T W 
Sbjct: 173 LPPVPADMVFLVDGSWSIGHSHFQQVKDFLASVIAPFEIGPDKVQVGLTQYSGDAQTEWD 232

Query: 360 NDLISATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILV 419
            + +S TK QV  A R   +++  GG       L  +   N     GL  P +  ++ILV
Sbjct: 233 LNSLS-TKEQVLAAVR---RLRYKGGNTFTGLALTHVLGQNLQPAAGLR-PEAAKVVILV 287

Query: 420 SDGDPTVGELKLSKIQKNVKENI 442
           +DG         +++ K++  N+
Sbjct: 288 TDGKSQDDVHTAARVLKDLGVNV 310


>gi|239735519 SET binding factor 1 [Homo sapiens]
          Length = 1893

 Score = 30.4 bits (67), Expect = 8.2
 Identities = 21/68 (30%), Positives = 33/68 (48%), Gaps = 3/68 (4%)

Query: 221 LRFLHV--PDTFEGHFDGVPVISKGQQKAHVSFKPTVAQQRICPNCRETAVDGELVVLYD 278
           L+ LHV  PD  + H + +  + +  ++     KP + + R+ P   E  +DG  V L  
Sbjct: 848 LKGLHVMVPDIVQMHIETLEAVQRESRRLPPIQKPKLLRPRLLPG-EECVLDGLRVYLLP 906

Query: 279 VKREEKAG 286
             REE AG
Sbjct: 907 DGREEGAG 914


>gi|197313748 SET domain containing 2 [Homo sapiens]
          Length = 2564

 Score = 30.4 bits (67), Expect = 8.2
 Identities = 17/67 (25%), Positives = 28/67 (41%)

Query: 624  PLTSLVIENEAGDERMLADAPPQDPSCCSGALYYGSKVVPDSTPSWANPSPTPVISMLAQ 683
            P+ + V  +     ++L   P  DP C      +   +V  ST   + P P PV+  +A 
Sbjct: 2172 PMQAYVDPSNPNAGKVLLPTPSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVVPHVAA 2231

Query: 684  GSQVLES 690
              +V  S
Sbjct: 2232 PVEVSSS 2238


>gi|48255968 UDP-glucose pyrophosphorylase 2 isoform b [Homo
           sapiens]
          Length = 497

 Score = 30.4 bits (67), Expect = 8.2
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 14/80 (17%)

Query: 794 SDTAQVTNQRVQISVKKE--KVVTITLDKEMS--------FSVLLHRVWKKHPVNVDFLG 843
           S   +V  Q +++SVKKE  K++T     E          F  L HR  ++   +VD+  
Sbjct: 7   SQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGK 66

Query: 844 IYIPPTNKFSP----KAHGL 859
           I  PP +   P    KA GL
Sbjct: 67  IQRPPEDSIQPYEKIKARGL 86


>gi|48255966 UDP-glucose pyrophosphorylase 2 isoform a [Homo
           sapiens]
          Length = 508

 Score = 30.4 bits (67), Expect = 8.2
 Identities = 25/80 (31%), Positives = 36/80 (45%), Gaps = 14/80 (17%)

Query: 794 SDTAQVTNQRVQISVKKE--KVVTITLDKEMS--------FSVLLHRVWKKHPVNVDFLG 843
           S   +V  Q +++SVKKE  K++T     E          F  L HR  ++   +VD+  
Sbjct: 18  SQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGPSVDWGK 77

Query: 844 IYIPPTNKFSP----KAHGL 859
           I  PP +   P    KA GL
Sbjct: 78  IQRPPEDSIQPYEKIKARGL 97


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.394 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,358,473
Number of Sequences: 37866
Number of extensions: 1595001
Number of successful extensions: 3890
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 3822
Number of HSP's gapped (non-prelim): 44
length of query: 946
length of database: 18,247,518
effective HSP length: 112
effective length of query: 834
effective length of database: 14,006,526
effective search space: 11681442684
effective search space used: 11681442684
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.