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Search of human proteins with 7019563
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019563 testes-specific protease 50 [Homo sapiens]
(385 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019563 testes-specific protease 50 [Homo sapiens] 809 0.0
gi|4506153 prostasin preproprotein [Homo sapiens] 156 3e-38
gi|13994276 marapsin [Homo sapiens] 153 2e-37
gi|117956391 protease, serine, 33 [Homo sapiens] 153 2e-37
gi|11545839 protease, serine, 22 [Homo sapiens] 151 1e-36
gi|5803197 testisin isoform 1 [Homo sapiens] 147 2e-35
gi|21614531 testisin isoform 2 [Homo sapiens] 145 5e-35
gi|33695155 hepsin [Homo sapiens] 142 4e-34
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens] 142 4e-34
gi|4504481 hepsin [Homo sapiens] 142 4e-34
gi|148806900 epidermis-specific serine protease-like protein [Ho... 141 9e-34
gi|205360905 testis-specific serine protease 1 [Homo sapiens] 140 3e-33
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens] 139 3e-33
gi|68508970 tryptase beta 2 precursor [Homo sapiens] 136 3e-32
gi|21614533 testisin isoform 3 [Homo sapiens] 135 8e-32
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens] 132 7e-31
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ... 132 7e-31
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ... 132 7e-31
gi|156938340 transmembrane tryptase preproprotein [Homo sapiens] 130 2e-30
gi|187761337 transmembrane protease, serine 11B [Homo sapiens] 129 4e-30
gi|116256363 transmembrane protease, serine 13 [Homo sapiens] 128 8e-30
gi|34098976 marapsin 2 [Homo sapiens] 128 8e-30
gi|4503627 coagulation factor XI precursor [Homo sapiens] 127 1e-29
gi|110815798 ovochymase 1 [Homo sapiens] 125 6e-29
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 125 8e-29
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa... 122 4e-28
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa... 122 4e-28
gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo s... 122 5e-28
gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo ... 122 5e-28
gi|23957702 transmembrane protease, serine 6 [Homo sapiens] 122 5e-28
>gi|7019563 testes-specific protease 50 [Homo sapiens]
Length = 385
Score = 809 bits (2090), Expect = 0.0
Identities = 385/385 (100%), Positives = 385/385 (100%)
Query: 1 MGRWCQTVARGQRPRTSAPSRAGALLLLLLLLRSAGCWGAGEAPGALSTADPADQSVQCV 60
MGRWCQTVARGQRPRTSAPSRAGALLLLLLLLRSAGCWGAGEAPGALSTADPADQSVQCV
Sbjct: 1 MGRWCQTVARGQRPRTSAPSRAGALLLLLLLLRSAGCWGAGEAPGALSTADPADQSVQCV 60
Query: 61 PKATCPSSRPRLLWQTPTTQTLPSTTMETQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAV 120
PKATCPSSRPRLLWQTPTTQTLPSTTMETQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAV
Sbjct: 61 PKATCPSSRPRLLWQTPTTQTLPSTTMETQFPVSEGKVDPYRSCGFSYEQDPTLRDPEAV 120
Query: 121 ARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQTASD 180
ARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQTASD
Sbjct: 121 ARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQTASD 180
Query: 181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC 240
VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC
Sbjct: 181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC 240
Query: 241 TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDT 300
TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDT
Sbjct: 241 TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDT 300
Query: 301 HREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQ 360
HREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQ
Sbjct: 301 HREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWDCLNGQ 360
Query: 361 ALALPAPSRTLLLALPLPLSLLAAL 385
ALALPAPSRTLLLALPLPLSLLAAL
Sbjct: 361 ALALPAPSRTLLLALPLPLSLLAAL 385
>gi|4506153 prostasin preproprotein [Homo sapiens]
Length = 343
Score = 156 bits (394), Expect = 3e-38
Identities = 82/238 (34%), Positives = 121/238 (50%), Gaps = 10/238 (4%)
Query: 119 AVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVIYSVRVGSPWIDQMTQ 176
AVA +WPW VS+ G H+C G++++ QWVL+ AHC Y V++G+ +D ++
Sbjct: 51 AVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQLDSYSE 110
Query: 177 TASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKD 236
A + +I H Y + G DI LL+L + + +S Y+RPICLP + +
Sbjct: 111 DAKVSTLKDIIPHPSYLQE------GSQGDIALLQLSRPITFSRYIRPICLPAANASFPN 164
Query: 237 HSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMC 296
CTVTGWG + +Q+ EV +++ + C N +N P ++ M+C
Sbjct: 165 GLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETC-NCLYNIDAKPEEPHFVQEDMVC 223
Query: 297 AEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
A K C +G PL C +EG WYL G+VSWG C P +Y SSY WI
Sbjct: 224 AGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDACGARNRPGVYTLASSYASWI 281
>gi|13994276 marapsin [Homo sapiens]
Length = 290
Score = 153 bits (387), Expect = 2e-37
Identities = 75/233 (32%), Positives = 127/233 (54%), Gaps = 9/233 (3%)
Query: 124 WPWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVIYSVRVGSPWIDQMTQTASDV 181
WPW VS++ NG+H C G++IA QWVLT AHC +Y V +G+ + Q A
Sbjct: 46 WPWQVSIQRNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQVLLGARQLVQPGPHAMYA 105
Query: 182 PVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCT 241
V QV + Y+ + D+ L++L+ + ++NY+ P+CLP + + C
Sbjct: 106 RVRQVESNPLYQG------TASSADVALVELEAPVPFTNYILPVCLPDPSVIFETGMNCW 159
Query: 242 VTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAE-DT 300
VTGWG + + P+ R +Q+ V I++ +C+ Y T+ + IK+ M+CA +
Sbjct: 160 VTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDMLCAGFEE 219
Query: 301 HREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
++ C +G PLVC + +W G++SWG GC + P +Y++V+++ +WI
Sbjct: 220 GKKDACKGDSGGPLVCLVGQSWLQAGVISWGEGCARQNRPGVYIRVTAHHNWI 272
>gi|117956391 protease, serine, 33 [Homo sapiens]
Length = 280
Score = 153 bits (387), Expect = 2e-37
Identities = 81/233 (34%), Positives = 120/233 (51%), Gaps = 9/233 (3%)
Query: 124 WPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVI--YSVRVGSPWIDQMTQTASDV 181
WPW S++ G H+C G++IA QWVLT AHC R + Y VR+G+ + + V
Sbjct: 48 WPWQASIQHRGAHVCGGSLIAPQWVLTAAHCFPRRALPAEYRVRLGALRLGSTSPRTLSV 107
Query: 182 PVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCT 241
PV +V++ Y G D+ LL+L++ + S V+P+CLP + C
Sbjct: 108 PVRRVLLPPDYSED------GARGDLALLQLRRPVPLSARVQPVCLPVPGARPPPGTPCR 161
Query: 242 VTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTH 301
VTGWG + P++R +Q V +L+++ CD YH +P +I+ +CA
Sbjct: 162 VTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVPQAERIVLPGSLCAGYPQ 221
Query: 302 REK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
K C +G PL C G+W LVG+VSWG GC P +Y V++Y WI
Sbjct: 222 GHKDACQGDSGGPLTCLQSGSWVLVGVVSWGKGCALPNRPGVYTSVATYSPWI 274
>gi|11545839 protease, serine, 22 [Homo sapiens]
Length = 317
Score = 151 bits (381), Expect = 1e-36
Identities = 84/280 (30%), Positives = 147/280 (52%), Gaps = 23/280 (8%)
Query: 103 SCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCL---IWRD 159
+CG + + + ++ WPW+VS++ NGTH CAG+++ S+WV+T AHC + +
Sbjct: 40 ACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKP 99
Query: 160 VIYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSW-VGQANDIGLLKLKQELKY 218
++SV +G+ + + V V V H Y SW G DI L++L++ +++
Sbjct: 100 YLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVY------SWKEGACADIALVRLERSIQF 153
Query: 219 SNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYH 278
S V PICLP L ++ C ++GWG + P +T+Q+ +V I++++ C + Y
Sbjct: 154 SERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYW 213
Query: 279 NFTKIPTLVQIIKSQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKS 337
+ + M+CA E+ C +G PL+C ++G W L G++SWG GC +
Sbjct: 214 RGAGQGPITE----DMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAER 269
Query: 338 EAPPIYLQVSSYQHWIWDCLNGQAL--------ALPAPSR 369
P +Y+ +S+++ W+ + G L AL APS+
Sbjct: 270 NRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQ 309
>gi|5803197 testisin isoform 1 [Homo sapiens]
Length = 314
Score = 147 bits (371), Expect = 2e-35
Identities = 85/272 (31%), Positives = 139/272 (51%), Gaps = 20/272 (7%)
Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQT 177
+A RWPW S+R +H+C ++++ +W LT AHC + + S W+ Q Q
Sbjct: 47 DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCF---ETYSDLSDPSGWMVQFGQL 103
Query: 178 ASDVPVLQVIM--HSRYRAQRFW---SWVGQAN-DIGLLKLKQELKYSNYVRPICLPGTD 231
S +P + ++RY + ++G + DI L+KL + Y+ +++PICL +
Sbjct: 104 TS-MPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQAST 162
Query: 232 YVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIK 291
+ ++ + C VTGWG K D P T+QE +V I+NN C++ + + + + I
Sbjct: 163 FEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY----SFRKDIF 218
Query: 292 SQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQ 350
M+CA + K C+ +G PL C+ G WY +G+VSWG GC + P +Y +S +
Sbjct: 219 GDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHHF 278
Query: 351 HWIWDCLNGQALALPAPSRTLLL-----ALPL 377
WI + ++ P PS LL ALPL
Sbjct: 279 EWIQKLMAQSGMSQPDPSWPLLFFPLLWALPL 310
>gi|21614531 testisin isoform 2 [Homo sapiens]
Length = 312
Score = 145 bits (367), Expect = 5e-35
Identities = 85/274 (31%), Positives = 139/274 (50%), Gaps = 26/274 (9%)
Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSP--WIDQMT 175
+A RWPW S+R +H+C ++++ +W LT AHC + + P W+ Q
Sbjct: 47 DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHC-------FETDLSDPSGWMVQFG 99
Query: 176 QTASDVPVLQVIM--HSRYRAQRFW---SWVGQAN-DIGLLKLKQELKYSNYVRPICLPG 229
Q S +P + ++RY + ++G + DI L+KL + Y+ +++PICL
Sbjct: 100 QLTS-MPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQA 158
Query: 230 TDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQI 289
+ + ++ + C VTGWG K D P T+QE +V I+NN C++ + + + +
Sbjct: 159 STFEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKY----SFRKD 214
Query: 290 IKSQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSS 348
I M+CA + K C+ +G PL C+ G WY +G+VSWG GC + P +Y +S
Sbjct: 215 IFGDMVCAGNAQGGKDACFGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISH 274
Query: 349 YQHWIWDCLNGQALALPAPSRTLLL-----ALPL 377
+ WI + ++ P PS LL ALPL
Sbjct: 275 HFEWIQKLMAQSGMSQPDPSWPLLFFPLLWALPL 308
>gi|33695155 hepsin [Homo sapiens]
Length = 417
Score = 142 bits (359), Expect = 4e-34
Identities = 85/243 (34%), Positives = 124/243 (51%), Gaps = 19/243 (7%)
Query: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD-VIYSVRVGSPWIDQMTQTASDV 181
RWPW VS+R +G H+C G++++ WVLT AHC R+ V+ RV + + Q + +
Sbjct: 173 RWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQL 232
Query: 182 PVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCT 241
V V+ H Y R + +NDI L+ L L + Y++P+CLP L D CT
Sbjct: 233 GVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICT 292
Query: 242 VTGWGLSKADGMWPQFRTIQEKEVIILNNKECD--NFYHNFTKIPTLVQIIKSQMMCAED 299
VTGWG ++ G Q +QE V I++N C+ +FY N IK +M CA
Sbjct: 293 VTGWGNTQYYGQ--QAGVLQEARVPIISNDVCNGADFYGN---------QIKPKMFCAGY 341
Query: 300 THRE-KFCYELTGEPLVC----SMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIW 354
C +G P VC S W L G+VSWG GC ++ P +Y +VS ++ WI+
Sbjct: 342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIF 401
Query: 355 DCL 357
+
Sbjct: 402 QAI 404
>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
Length = 638
Score = 142 bits (359), Expect = 4e-34
Identities = 84/242 (34%), Positives = 122/242 (50%), Gaps = 34/242 (14%)
Query: 124 WPWMVSVRANGT---HICAGTIIASQWVLTVAHCL-------IWRDVIYSVRVGSPWIDQ 173
WPW VS++ T H+C G++I QWVLT AHC +WR IYS G +
Sbjct: 402 WPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWR--IYS---GILNLSD 456
Query: 174 MTQTASDVPVLQVIMHSRYRAQRFWSWVGQAN-DIGLLKLKQELKYSNYVRPICLPGTDY 232
+T+ + ++I+H Y+ V + N DI L+KL+ L Y+ + +PICLP
Sbjct: 457 ITKDTPFSQIKEIIIHQNYK-------VSEGNHDIALIKLQAPLNYTEFQKPICLPSKGD 509
Query: 233 VLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKS 292
++ C VTGWG SK G +Q+ + ++ N+EC Y ++ I
Sbjct: 510 TSTIYTNCWVTGWGFSKEKGEIQNI--LQKVNIPLVTNEECQKRYQDYK--------ITQ 559
Query: 293 QMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQH 351
+M+CA K C +G PLVC G W LVG+ SWG GC + E P +Y +V+ Y
Sbjct: 560 RMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMD 619
Query: 352 WI 353
WI
Sbjct: 620 WI 621
>gi|4504481 hepsin [Homo sapiens]
Length = 417
Score = 142 bits (359), Expect = 4e-34
Identities = 85/243 (34%), Positives = 124/243 (51%), Gaps = 19/243 (7%)
Query: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD-VIYSVRVGSPWIDQMTQTASDV 181
RWPW VS+R +G H+C G++++ WVLT AHC R+ V+ RV + + Q + +
Sbjct: 173 RWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGAVAQASPHGLQL 232
Query: 182 PVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCT 241
V V+ H Y R + +NDI L+ L L + Y++P+CLP L D CT
Sbjct: 233 GVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKICT 292
Query: 242 VTGWGLSKADGMWPQFRTIQEKEVIILNNKECD--NFYHNFTKIPTLVQIIKSQMMCAED 299
VTGWG ++ G Q +QE V I++N C+ +FY N IK +M CA
Sbjct: 293 VTGWGNTQYYGQ--QAGVLQEARVPIISNDVCNGADFYGN---------QIKPKMFCAGY 341
Query: 300 THRE-KFCYELTGEPLVC----SMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIW 354
C +G P VC S W L G+VSWG GC ++ P +Y +VS ++ WI+
Sbjct: 342 PEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWIF 401
Query: 355 DCL 357
+
Sbjct: 402 QAI 404
>gi|148806900 epidermis-specific serine protease-like protein [Homo
sapiens]
Length = 328
Score = 141 bits (356), Expect = 9e-34
Identities = 82/254 (32%), Positives = 124/254 (48%), Gaps = 14/254 (5%)
Query: 104 CGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVI 161
CG + +A A RWPW VS+ + IC G++++ + +LT AHC+ W
Sbjct: 19 CGQPVYSSRVVGGQDAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQPTWTTFS 78
Query: 162 YSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNY 221
Y+V +GS + + V ++++H +Y+ D+ LLKL ++ +++
Sbjct: 79 YTVWLGSITVGDSRKRVKYY-VSKIVIHPKYQ--------DTTADVALLKLSSQVTFTSA 129
Query: 222 VRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNF- 280
+ PICLP L C VTGWG K +QE EV I++ + C+ Y+
Sbjct: 130 ILPICLPSVTKQLAIPPFCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIG 189
Query: 281 TKIPTLVQIIKSQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEA 339
+P L +IK +CA DT K C +G PL C ++G W G+VSWG C KS
Sbjct: 190 IFLPALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQTGVVSWGLECGKS-L 248
Query: 340 PPIYLQVSSYQHWI 353
P +Y V YQ WI
Sbjct: 249 PGVYTNVIYYQKWI 262
>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
Length = 318
Score = 140 bits (352), Expect = 3e-33
Identities = 89/264 (33%), Positives = 130/264 (49%), Gaps = 20/264 (7%)
Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQ- 176
E+ RWPW S+R H C G++++ +WVL+ AHC ++ Y S W Q+ +
Sbjct: 60 ESARGRWPWQASLRLRRRHRCGGSLLSRRWVLSAAHC--FQKHYYP----SEWTVQLGEL 113
Query: 177 TASDVPVLQVIMHSRYRAQRFW----SWVGQANDIGLLKLKQELKYSNYVRPICLPGTDY 232
T+ P SRY+ Q + NDI LL+L + Y+ Y++PIC+ + +
Sbjct: 114 TSRPTPWNLRAYSSRYKVQDIIVNPDALGVLRNDIALLRLASSVTYNAYIQPICIESSTF 173
Query: 233 VLKDHSRCTVTGWGLSKADGM-WPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIK 291
C VTGWGL G P ++E +V ILNN C+ + P+ +I
Sbjct: 174 NFVHRPDCWVTGWGLISPSGTPLPPPYNLREAQVTILNNTRCNYLFEQ----PSSRSMIW 229
Query: 292 SQMMCA--EDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSY 349
M CA ED + C +G PLVC +G WY VG+VSWG C + P +Y +S Y
Sbjct: 230 DSMFCAGAEDGSVDT-CKGDSGGPLVCDKDGLWYQVGIVSWGMDCGQPNRPGVYTNISVY 288
Query: 350 QHWIWDCLNGQALALPAPSRTLLL 373
HWI ++ + P PS+ LLL
Sbjct: 289 FHWIRRVMS-HSTPRPNPSQLLLL 311
>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
Length = 275
Score = 139 bits (351), Expect = 3e-33
Identities = 85/246 (34%), Positives = 128/246 (52%), Gaps = 24/246 (9%)
Query: 118 EAVARRWPWMVSVRANGT---HICAGTIIASQWVLTVAHCLIWRDV--IYSVRVGSP--- 169
EA +WPW VS+R +G H C G++I QWVLT AHC + DV + ++RV
Sbjct: 36 EAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQLREQH 94
Query: 170 --WIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICL 227
+ DQ+ +PV ++I+H ++ + + DI LL+L++ + S++V + L
Sbjct: 95 LYYQDQL------LPVSRIIVHPQFYTAQIGA------DIALLELEEPVNVSSHVHTVTL 142
Query: 228 PGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLV 287
P C VTGWG D P +++ +V I+ N CD YH V
Sbjct: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202
Query: 288 QIIKSQMMCAEDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVS 347
+I++ M+CA +T R+ C +G PLVC + GTW G+VSWG GC + P IY +V+
Sbjct: 203 RIVRDDMLCAGNTRRDS-CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261
Query: 348 SYQHWI 353
Y WI
Sbjct: 262 YYLDWI 267
>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
Length = 275
Score = 136 bits (343), Expect = 3e-32
Identities = 84/246 (34%), Positives = 126/246 (51%), Gaps = 24/246 (9%)
Query: 118 EAVARRWPWMVSVRANGT---HICAGTIIASQWVLTVAHCLIWRDV--IYSVRVGSP--- 169
EA +WPW VS+R H C G++I QWVLT AHC + DV + ++RV
Sbjct: 36 EAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHC-VGPDVKDLAALRVQLREQH 94
Query: 170 --WIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICL 227
+ DQ+ +PV ++I+H ++ + + DI LL+L++ + S++V + L
Sbjct: 95 LYYQDQL------LPVSRIIVHPQFYTAQIGA------DIALLELEEPVNVSSHVHTVTL 142
Query: 228 PGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLV 287
P C VTGWG D P +++ +V I+ N CD YH V
Sbjct: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202
Query: 288 QIIKSQMMCAEDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVS 347
+I++ M+CA +T R+ C +G PLVC + GTW G+VSWG GC + P IY +V+
Sbjct: 203 RIVRDDMLCAGNTRRDS-CQGDSGGPLVCKVNGTWLQAGVVSWGEGCAQPNRPGIYTRVT 261
Query: 348 SYQHWI 353
Y WI
Sbjct: 262 YYLDWI 267
>gi|21614533 testisin isoform 3 [Homo sapiens]
Length = 300
Score = 135 bits (339), Expect = 8e-32
Identities = 80/273 (29%), Positives = 133/273 (48%), Gaps = 36/273 (13%)
Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQMTQT 177
+A RWPW S+R +H+C ++++ +W LT AHC + + S W+ Q Q
Sbjct: 47 DAELGRWPWQGSLRLWDSHVCGVSLLSHRWALTAAHCF---ETYSDLSDPSGWMVQFGQL 103
Query: 178 ASDVPVLQVIM--HSRYRAQRFW---SWVGQAN-DIGLLKLKQELKYSNYVRPICLPGTD 231
S +P + ++RY + ++G + DI L+KL + Y+ +++PICL +
Sbjct: 104 TS-MPSFWSLQAYYTRYFVSNIYLSPRYLGNSPYDIALVKLSAPVTYTKHIQPICLQAST 162
Query: 232 YVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIK 291
+ ++ + C VTGWG K D P T+QE +V I+NN C++ + ++
Sbjct: 163 FEFENRTDCWVTGWGYIKEDEALPSPHTLQEVQVAIINNSMCNHLFLKYS---------- 212
Query: 292 SQMMCAEDTHREKFCYEL--TGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSY 349
R+ ++ +G PL C+ G WY +G+VSWG GC + P +Y +S +
Sbjct: 213 ---------FRKDIFGDMGDSGGPLACNKNGLWYQIGVVSWGVGCGRPNRPGVYTNISHH 263
Query: 350 QHWIWDCLNGQALALPAPSRTLLL-----ALPL 377
WI + ++ P PS LL ALPL
Sbjct: 264 FEWIQKLMAQSGMSQPDPSWPLLFFPLLWALPL 296
>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
Length = 410
Score = 132 bits (331), Expect = 7e-31
Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 24/249 (9%)
Query: 122 RRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLI----WRDVIYSVRVGSPWIDQMTQT 177
++WPW VS++ + H C G++I +WVLT AHC+ W + + W DQ +
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRW-DQAWKH 230
Query: 178 ASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDH 237
D+ I S + + +DI L L + YS++++P CLP + ++
Sbjct: 231 LEDI-----IFPSNF------DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAG 279
Query: 238 SRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA 297
+ C VTGWG P +QE E+ I+ +++C N K + +++ +C
Sbjct: 280 TECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKN--KNISKSKMVTRGTVCG 337
Query: 298 EDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWD-- 355
+ + C +G PLVC + GTW VG+VSWG GC + P +Y +VS Y+ WI D
Sbjct: 338 YNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397
Query: 356 ----CLNGQ 360
CLN +
Sbjct: 398 RQASCLNSK 406
>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
sapiens]
Length = 410
Score = 132 bits (331), Expect = 7e-31
Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 24/249 (9%)
Query: 122 RRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLI----WRDVIYSVRVGSPWIDQMTQT 177
++WPW VS++ + H C G++I +WVLT AHC+ W + + W DQ +
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRW-DQAWKH 230
Query: 178 ASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDH 237
D+ I S + + +DI L L + YS++++P CLP + ++
Sbjct: 231 LEDI-----IFPSNF------DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAG 279
Query: 238 SRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA 297
+ C VTGWG P +QE E+ I+ +++C N K + +++ +C
Sbjct: 280 TECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKN--KNISKSKMVTRGTVCG 337
Query: 298 EDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWD-- 355
+ + C +G PLVC + GTW VG+VSWG GC + P +Y +VS Y+ WI D
Sbjct: 338 YNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397
Query: 356 ----CLNGQ 360
CLN +
Sbjct: 398 RQASCLNSK 406
>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
sapiens]
Length = 410
Score = 132 bits (331), Expect = 7e-31
Identities = 76/249 (30%), Positives = 122/249 (48%), Gaps = 24/249 (9%)
Query: 122 RRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLI----WRDVIYSVRVGSPWIDQMTQT 177
++WPW VS++ + H C G++I +WVLT AHC+ W + + W DQ +
Sbjct: 172 KKWPWQVSLQTSNIHHCGGSLIDRRWVLTAAHCVFRGCGWEGGRWLLAGIGRW-DQAWKH 230
Query: 178 ASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDH 237
D+ I S + + +DI L L + YS++++P CLP + ++
Sbjct: 231 LEDI-----IFPSNF------DFATLTSDIALALLAYSVNYSSHIQPACLPEKLFEVEAG 279
Query: 238 SRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA 297
+ C VTGWG P +QE E+ I+ +++C N K + +++ +C
Sbjct: 280 TECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKN--KNISKSKMVTRGTVCG 337
Query: 298 EDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIWD-- 355
+ + C +G PLVC + GTW VG+VSWG GC + P +Y +VS Y+ WI D
Sbjct: 338 YNDQGKDACQGDSGGPLVCELNGTWVQVGIVSWGIGCGRKGYPGVYTEVSFYKKWIIDHL 397
Query: 356 ----CLNGQ 360
CLN +
Sbjct: 398 RQASCLNSK 406
>gi|156938340 transmembrane tryptase preproprotein [Homo sapiens]
Length = 321
Score = 130 bits (327), Expect = 2e-30
Identities = 75/237 (31%), Positives = 116/237 (48%), Gaps = 17/237 (7%)
Query: 119 AVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIW--RDVIYSVRVGSPWIDQMTQ 176
A A WPW S+R H+C G++++ QWVLT AHC Y V +G ++T
Sbjct: 44 APAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGEL---EITL 100
Query: 177 TASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKD 236
+ V Q+I+HS Q G + DI L++L + S+ + P+CLP
Sbjct: 101 SPHFSTVRQIILHSSPSGQP-----GTSGDIALVELSVPVTLSSRILPVCLPEASDDFCP 155
Query: 237 HSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMC 296
RC VTGWG ++ P +++E +V +++ + C Y I++ M+C
Sbjct: 156 GIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGG-----SILQPDMLC 210
Query: 297 AEDTHREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
A C + +G PLVC + G W G+VSWG GC + P +Y +V +Y +WI
Sbjct: 211 ARGPGDA--CQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWI 265
>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
Length = 416
Score = 129 bits (324), Expect = 4e-30
Identities = 74/238 (31%), Positives = 118/238 (49%), Gaps = 31/238 (13%)
Query: 124 WPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD------VIYSVRVGSPWIDQMTQT 177
WPW S++ G H C ++I+S+W+L+ AHC ++ V + + V P++ + Q
Sbjct: 196 WPWQASMQWKGRHYCGASLISSRWLLSAAHCFAKKNNSKDWTVNFGIVVNKPYMTRKVQN 255
Query: 178 ASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDH 237
+I H Y + G +DI L++L +E+ ++ Y+R ICLP L ++
Sbjct: 256 --------IIFHENYSSP------GLHDDIALVQLAEEVSFTEYIRKICLPEAKMKLSEN 301
Query: 238 SRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA 297
VTGWG +G +P +QE + I++NK C+ Y + M+CA
Sbjct: 302 DNVVVTGWGTLYMNGSFPVI--LQEDFLKIIDNKICNASY-------AYSGFVTDTMLCA 352
Query: 298 EDTHREK-FCYELTGEPLVC-SMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
E C +G PL W+LVG+VSWG GC K P +Y +V+SY++WI
Sbjct: 353 GFMSGEADACQNDSGGPLAYPDSRNIWHLVGIVSWGDGCGKKNKPGVYTRVTSYRNWI 410
>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
Length = 567
Score = 128 bits (322), Expect = 8e-30
Identities = 75/246 (30%), Positives = 127/246 (51%), Gaps = 28/246 (11%)
Query: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHC-LIWRDVI---YSVRVGSPWIDQMTQTA 178
+WPW VS+ THIC GT+I +QWVLT AHC + R+ + + V G+ + Q+ + A
Sbjct: 336 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA 395
Query: 179 SDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHS 238
S + ++I++S Y + DI L++L + L S ++ P CLP +
Sbjct: 396 S---IAEIIINSNYTDEE------DDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNE 446
Query: 239 RCTVTGWGLSK-ADGMWPQFRTIQEKEVIILNNKECDNF--YHNFTKIPTLVQIIKSQMM 295
C +TG+G ++ D F ++E +V +++ K+C+++ Y ++ + +MM
Sbjct: 447 TCWITGFGKTRETDDKTSPF--LREVQVNLIDFKKCNDYLVYDSY---------LTPRMM 495
Query: 296 CAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWIW 354
CA D + C +G PLVC WYL G+ SWG GC + P +Y +V+ WI+
Sbjct: 496 CAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIY 555
Query: 355 DCLNGQ 360
+ +
Sbjct: 556 SKMESE 561
>gi|34098976 marapsin 2 [Homo sapiens]
Length = 326
Score = 128 bits (322), Expect = 8e-30
Identities = 94/288 (32%), Positives = 132/288 (45%), Gaps = 23/288 (7%)
Query: 103 SCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD--- 159
+CG + L A R+WPW VSV G H+C G+I+ WVL+ AHC RD
Sbjct: 50 ACGRPSMEGKILGGVPAPERKWPWQVSVHYAGLHVCGGSILNEYWVLSAAHC-FHRDKNI 108
Query: 160 VIYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYS 219
IY + VG + V +VI+H Y + +G D+ L++LK + +S
Sbjct: 109 KIYDMYVGLVNLRVAGNHTQWYEVNRVILHPTY---EMYHPIG--GDVALVQLKTRIVFS 163
Query: 220 NYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHN 279
V P+CL T V + C TGWGL G +QE ++ ++ C Y +
Sbjct: 164 ESVLPVCL-ATPEVNLTSANCWATGWGLVSKQGETSD--ELQEMQLPLILEPWCHLLYGH 220
Query: 280 FTKIPTLVQIIKSQMMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSE 338
+ I M+CA D K C +G PLVC +W +G+VSWG GC
Sbjct: 221 -------MSYIMPDMLCAGDILNAKTVCEGDSGGPLVCEFNRSWLQIGIVSWGRGCSNPL 273
Query: 339 APPIYLQVSSYQHWIWDCLNGQALALPA-PSRTLLLALPLPLSLLAAL 385
P +Y VS + WI C N + PA P+ L AL LS+L A+
Sbjct: 274 YPGVYASVSYFSKWI--CDNIEITPTPAQPAPALSPALGPTLSVLMAM 319
>gi|4503627 coagulation factor XI precursor [Homo sapiens]
Length = 625
Score = 127 bits (320), Expect = 1e-29
Identities = 78/241 (32%), Positives = 116/241 (48%), Gaps = 22/241 (9%)
Query: 119 AVARRWPWMVSVRANGT---HICAGTIIASQWVLTVAHCLIWRDVIYSVRVGSPWIDQ-- 173
+V WPW V++ H+C G+II +QW+LT AHC + +RV S ++Q
Sbjct: 394 SVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSGILNQSE 453
Query: 174 MTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYV 233
+ + S V ++I+H +Y+ DI LLKL+ + Y++ RPICLP
Sbjct: 454 IKEDTSFFGVQEIIIHDQYKMAE------SGYDIALLKLETTVNYTDSQRPICLPSKGDR 507
Query: 234 LKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQ 293
++ C VTGWG K T+Q+ ++ ++ N+EC Y I +
Sbjct: 508 NVIYTDCWVTGWGYRKLRDKIQN--TLQKAKIPLVTNEECQKRYRGHK--------ITHK 557
Query: 294 MMCAEDTHREK-FCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHW 352
M+CA K C +G PL C W+LVG+ SWG GC + E P +Y V Y W
Sbjct: 558 MICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGEGCAQRERPGVYTNVVEYVDW 617
Query: 353 I 353
I
Sbjct: 618 I 618
>gi|110815798 ovochymase 1 [Homo sapiens]
Length = 1134
Score = 125 bits (314), Expect = 6e-29
Identities = 85/267 (31%), Positives = 130/267 (48%), Gaps = 19/267 (7%)
Query: 118 EAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD--VIYSVRVGSPWIDQMT 175
EA WPW V +R G + C G II W+LT AHC+ ++ + +++ G +
Sbjct: 580 EACPHCWPWQVGLRFLGDYQCGGAIINPVWILTAAHCVQLKNNPLSWTIIAGDHDRNLKE 639
Query: 176 QTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLK 235
T +I+H + + S DI L++L L+Y++ VRP+CLP + L
Sbjct: 640 STEQVRRAKHIIVHEDFNTLSYDS------DIALIQLSSPLEYNSVVRPVCLPHSAEPLF 693
Query: 236 DHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMM 295
C VTGWG ADG +Q+ +V +L + C++ Y++ I +M+
Sbjct: 694 SSEICAVTGWGSISADGGLAS--RLQQIQVHVLEREVCEHTYYS-----AHPGGITEKMI 746
Query: 296 CA--EDTHREKFCYELTGEPLVCSME-GTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHW 352
CA + + FC +G PLVC E G + L G+VSWGAGC + P ++ +V + W
Sbjct: 747 CAGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSWGAGCVQPWKPGVFARVMIFLDW 806
Query: 353 IWDCLNGQA-LALPAPSRTLLLALPLP 378
I +NG A L +TL LP P
Sbjct: 807 IQSKINGPASLQTNNKCKTLKQQLPPP 833
Score = 104 bits (260), Expect = 1e-22
Identities = 69/223 (30%), Positives = 110/223 (49%), Gaps = 20/223 (8%)
Query: 125 PWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVIYSVRV--GSPWIDQMTQTASD 180
PW VS++++ H C G++I V+T AHCL + + ++ V G + Q + +
Sbjct: 59 PWQVSLKSDEHHFCGGSLIQEDRVVTAAHCLDSLSEKQLKNITVTSGEYSLFQKDKQEQN 118
Query: 181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC 240
+PV ++I H Y ++ + S DI LL LK ++K+ N V+PICLP +D ++ C
Sbjct: 119 IPVSKIITHPEYNSREYMS-----PDIALLYLKHKVKFGNAVQPICLPDSDDKVEPGILC 173
Query: 241 TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCA--E 298
+GWG K +QE E+ I++++ C+ + P + M+CA
Sbjct: 174 LSSGWG--KISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPP-----LGRTMLCAGFP 226
Query: 299 DTHREKFCYELTGEPLVCSM-EGTWYLVGLVSWGAGCQKSEAP 340
D + C +G PLVC G W L G+ SW AGC P
Sbjct: 227 DWGMDA-CQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVP 268
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 125 bits (313), Expect = 8e-29
Identities = 70/234 (29%), Positives = 118/234 (50%), Gaps = 19/234 (8%)
Query: 123 RWPWMVSVRANGTHICAGTIIASQWVLTVAHCL--IWRDVIYSVRVGSPWIDQMTQTASD 180
+WPW S++ G H+C G++I W++T AHC+ ++ ++++VG + + A
Sbjct: 227 QWPWQASLQFQGYHLCGGSVITPLWIITAAHCVYDLYLPKSWTIQVG--LVSLLDNPAPS 284
Query: 181 VPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRC 240
V +++ HS+Y+ +R NDI L+KL L ++ ++P+CLP ++ D C
Sbjct: 285 HLVEKIVYHSKYKPKRL------GNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKVC 338
Query: 241 TVTGWGLSKADGMWPQFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAED- 299
+GWG ++ DG + V +++NK C++ II M+CA
Sbjct: 339 WTSGWGATE-DGAGDASPVLNHAAVPLISNKICNH-------RDVYGGIISPSMLCAGYL 390
Query: 300 THREKFCYELTGEPLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
T C +G PLVC W LVG S+G GC + P +Y +V+S+ WI
Sbjct: 391 TGGVDSCQGDSGGPLVCQERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWI 444
>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
sapiens]
Length = 529
Score = 122 bits (307), Expect = 4e-28
Identities = 72/265 (27%), Positives = 122/265 (46%), Gaps = 35/265 (13%)
Query: 103 SCGF---SYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD 159
+CG S Q + A+ WPW VS+ H+C G+II +W++T AHC+
Sbjct: 280 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCV---- 335
Query: 160 VIYSVRVGSPW---------IDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLL 210
+ +PW + V +VI H Y ++ + NDI L+
Sbjct: 336 ---EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKT------KNNDIALM 386
Query: 211 KLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNN 270
KL++ L +++ V+P+CLP +L+ C ++GWG ++ G + + +V+++
Sbjct: 387 KLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIET 444
Query: 271 KECDNFYHNFTKIPTLVQIIKSQMMCAEDTH-REKFCYELTGEPLVCSMEGTWYLVGLVS 329
+ C++ Y +I M+CA C +G PLV S W+L+G S
Sbjct: 445 QRCNSRY-------VYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTS 497
Query: 330 WGAGCQKSEAPPIYLQVSSYQHWIW 354
WG+GC K+ P +Y V + WI+
Sbjct: 498 WGSGCAKAYRPGVYGNVMVFTDWIY 522
>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
sapiens]
Length = 492
Score = 122 bits (307), Expect = 4e-28
Identities = 72/265 (27%), Positives = 122/265 (46%), Gaps = 35/265 (13%)
Query: 103 SCGF---SYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCLIWRD 159
+CG S Q + A+ WPW VS+ H+C G+II +W++T AHC+
Sbjct: 243 ACGVNLNSSRQSRIVGGESALPGAWPWQVSLHVQNVHVCGGSIITPEWIVTAAHCV---- 298
Query: 160 VIYSVRVGSPW---------IDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLL 210
+ +PW + V +VI H Y ++ + NDI L+
Sbjct: 299 ---EKPLNNPWHWTAFAGILRQSFMFYGAGYQVEKVISHPNYDSKT------KNNDIALM 349
Query: 211 KLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNN 270
KL++ L +++ V+P+CLP +L+ C ++GWG ++ G + + +V+++
Sbjct: 350 KLQKPLTFNDLVKPVCLPNPGMMLQPEQLCWISGWGATEEKGKTSE--VLNAAKVLLIET 407
Query: 271 KECDNFYHNFTKIPTLVQIIKSQMMCAEDTH-REKFCYELTGEPLVCSMEGTWYLVGLVS 329
+ C++ Y +I M+CA C +G PLV S W+L+G S
Sbjct: 408 QRCNSRY-------VYDNLITPAMICAGFLQGNVDSCQGDSGGPLVTSKNNIWWLIGDTS 460
Query: 330 WGAGCQKSEAPPIYLQVSSYQHWIW 354
WG+GC K+ P +Y V + WI+
Sbjct: 461 WGSGCAKAYRPGVYGNVMVFTDWIY 485
>gi|239753547 PREDICTED: similar to 1700112C13Rik protein [Homo
sapiens]
Length = 282
Score = 122 bits (306), Expect = 5e-28
Identities = 86/281 (30%), Positives = 132/281 (46%), Gaps = 54/281 (19%)
Query: 79 TQTLPSTTMETQFPVSEGKVDPY-RSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHI 137
T L S ++ Q P EG P+ R+CG + ++ +WPW VS+ GT+I
Sbjct: 12 TSPLSSARLDYQ-PSIEG---PWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYI 67
Query: 138 CAGTIIASQWVLTVAHCL-IWRDV-IYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQ 195
C+G++I QWVLT AHCL ++D+ +YSV VG + Q + ++ +P+ ++++H +
Sbjct: 68 CSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL 124
Query: 196 RFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWP 255
+ DI LLKL+ + +S +V+P+CLP + S C V GWG + G
Sbjct: 125 -------MSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKG--- 174
Query: 256 QFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCYELT---GE 312
LN+ + S C E RE F + LT G
Sbjct: 175 -----------FLNHPD-------------------SVKSCCEFI-RECFQFTLTVDSGS 203
Query: 313 PLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
LVC M+ TW +G+VSW C + P IY + + WI
Sbjct: 204 SLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
>gi|239742014 PREDICTED: hypothetical protein XP_002342372 [Homo
sapiens]
Length = 282
Score = 122 bits (306), Expect = 5e-28
Identities = 86/281 (30%), Positives = 132/281 (46%), Gaps = 54/281 (19%)
Query: 79 TQTLPSTTMETQFPVSEGKVDPY-RSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHI 137
T L S ++ Q P EG P+ R+CG + ++ +WPW VS+ GT+I
Sbjct: 12 TSPLSSARLDYQ-PSIEG---PWLRACGQTNVSCRVVKGKLVEVGKWPWQVSILFLGTYI 67
Query: 138 CAGTIIASQWVLTVAHCL-IWRDV-IYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQ 195
C+G++I QWVLT AHCL ++D+ +YSV VG + Q + ++ +P+ ++++H +
Sbjct: 68 CSGSLIHHQWVLTAAHCLQRFKDLSLYSVMVG---VHQRPENSTQLPLTRMVIHKDFSNL 124
Query: 196 RFWSWVGQANDIGLLKLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWP 255
+ DI LLKL+ + +S +V+P+CLP + S C V GWG + G
Sbjct: 125 -------MSQDIALLKLRDSISWSPFVQPVCLPNIKFKPSIGSMCWVIGWGTTGKKG--- 174
Query: 256 QFRTIQEKEVIILNNKECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREKFCYELT---GE 312
LN+ + S C E RE F + LT G
Sbjct: 175 -----------FLNHPD-------------------SVKSCCEFI-RECFQFTLTVDSGS 203
Query: 313 PLVCSMEGTWYLVGLVSWGAGCQKSEAPPIYLQVSSYQHWI 353
LVC M+ TW +G+VSW C + P IY + + WI
Sbjct: 204 SLVCQMDKTWIQIGVVSWSFSCGQRHFPGIYTSTAHFNQWI 244
>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
Length = 811
Score = 122 bits (306), Expect = 5e-28
Identities = 72/265 (27%), Positives = 119/265 (44%), Gaps = 23/265 (8%)
Query: 95 EGKVDPYRSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHC 154
+G + + CG + + WPW S++ G HIC G +IA +WV+T AHC
Sbjct: 559 DGSDEEHCDCGLQGPSSRIVGGAVSSEGEWPWQASLQVRGRHICGGALIADRWVITAAHC 618
Query: 155 L----IWRDVIYSVRVGSPWIDQMTQTASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLL 210
+ V+++V +G W + V ++++H + D+ LL
Sbjct: 619 FQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEED------SHDYDVALL 672
Query: 211 KLKQELKYSNYVRPICLPGTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEKEVIILNN 270
+L + S VRP+CLP + + C +TGWG + G P +Q+ +V ++
Sbjct: 673 QLDHPVVRSAAVRPVCLPARSHFFEPGLHCWITGWGALREGG--PISNALQKVDVQLIPQ 730
Query: 271 KECDNFYHNFTKIPTLVQIIKSQMMCAEDTHREK-FCYELTGEPLVC-SMEGTWYLVGLV 328
C Y + +M+CA +K C +G PLVC ++ G W+L GLV
Sbjct: 731 DLCSEVYR---------YQVTPRMLCAGYRKGKKDACQGDSGGPLVCKALSGRWFLAGLV 781
Query: 329 SWGAGCQKSEAPPIYLQVSSYQHWI 353
SWG GC + +Y +++ WI
Sbjct: 782 SWGLGCGRPNYFGVYTRITGVISWI 806
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.447
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,222,375
Number of Sequences: 37866
Number of extensions: 764361
Number of successful extensions: 2699
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 2217
Number of HSP's gapped (non-prelim): 200
length of query: 385
length of database: 18,247,518
effective HSP length: 104
effective length of query: 281
effective length of database: 14,309,454
effective search space: 4020956574
effective search space used: 4020956574
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.