Search of human proteins with 13699256

Search of human proteins with 13699256

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13699256 protein phosphatase 1 regulatory inhibitor subunit
8 isoform alpha [Homo sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13699256 protein phosphatase 1 regulatory inhibitor subunit 8...   721   0.0  
gi|20336239 protein phosphatase 1 regulatory inhibitor subunit 8...   429   e-120
gi|4506015 protein phosphatase 1 regulatory inhibitor subunit 8 ...   265   4e-71
gi|21314720 Smad nuclear interacting protein [Homo sapiens]            67   3e-11
gi|155722990 solute carrier family 4 (anion exchanger), member 1...    65   7e-11
gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo sapi...    45   1e-04
gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]    40   0.004
gi|109255228 centrosomal protein 170kDa isoform alpha [Homo sapi...    40   0.004
gi|109255232 centrosomal protein 170kDa isoform gamma [Homo sapi...    40   0.004
gi|39725952 angiogenic factor VG5Q [Homo sapiens]                      35   0.10 
gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]     35   0.13 
gi|55743112 NAD kinase [Homo sapiens]                                  33   0.50 
gi|29826335 eukaryotic translation initiation factor 2 beta [Hom...    33   0.50 
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ...    32   0.65 
gi|29336043 caytaxin [Homo sapiens]                                    32   0.65 
gi|239742740 PREDICTED: hypothetical protein XP_002342615 [Homo ...    32   0.85 
gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]                   32   0.85 
gi|223468693 hypothetical protein LOC100130361 [Homo sapiens]          32   1.1  
gi|223468690 hypothetical protein LOC100132994 [Homo sapiens]          32   1.1  
gi|44681484 cell division cycle associated 2 [Homo sapiens]            32   1.1  
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  31   1.5  
gi|28372497 ubiquitin protein ligase E3 component n-recognin 1 [...    31   1.5  
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s...    31   1.5  
gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]            31   1.9  
gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]            31   1.9  
gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]            31   1.9  
gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]            31   1.9  
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...    31   1.9  
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...    31   1.9  
gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]             31   1.9  

>gi|13699256 protein phosphatase 1 regulatory inhibitor subunit 8
           isoform alpha [Homo sapiens]
          Length = 351

 Score =  721 bits (1861), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDF 60
           MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDF
Sbjct: 1   MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDF 60

Query: 61  TIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGAS 120
           TIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGAS
Sbjct: 61  TIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGAS 120

Query: 121 TRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTL 180
           TRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTL
Sbjct: 121 TRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTL 180

Query: 181 TIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEG 240
           TIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEG
Sbjct: 181 TIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEG 240

Query: 241 PGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPD 300
           PGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPD
Sbjct: 241 PGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPD 300

Query: 301 VDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI 351
           VDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI
Sbjct: 301 VDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI 351


>gi|20336239 protein phosphatase 1 regulatory inhibitor subunit 8
           isoform beta/delta [Homo sapiens]
          Length = 209

 Score =  429 bits (1102), Expect = e-120
 Identities = 209/209 (100%), Positives = 209/209 (100%)

Query: 143 MGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVT 202
           MGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVT
Sbjct: 1   MGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVT 60

Query: 203 FSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGG 262
           FSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGG
Sbjct: 61  FSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGG 120

Query: 263 LYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVY 322
           LYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVY
Sbjct: 121 LYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVY 180

Query: 323 NPEAVNEPKKKKYAKEAWPGKKPTPSLLI 351
           NPEAVNEPKKKKYAKEAWPGKKPTPSLLI
Sbjct: 181 NPEAVNEPKKKKYAKEAWPGKKPTPSLLI 209


>gi|4506015 protein phosphatase 1 regulatory inhibitor subunit 8
           isoform gamma [Homo sapiens]
          Length = 127

 Score =  265 bits (678), Expect = 4e-71
 Identities = 127/127 (100%), Positives = 127/127 (100%)

Query: 225 MVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGT 284
           MVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGT
Sbjct: 1   MVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGT 60

Query: 285 ALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKK 344
           ALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKK
Sbjct: 61  ALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKK 120

Query: 345 PTPSLLI 351
           PTPSLLI
Sbjct: 121 PTPSLLI 127


>gi|21314720 Smad nuclear interacting protein [Homo sapiens]
          Length = 396

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 41/145 (28%), Positives = 67/145 (46%), Gaps = 11/145 (7%)

Query: 17  PTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVHAALVY 76
           P  A  P     L   K D+++  + I  +  YL GR+  + D  IDH SCS+ HA   Y
Sbjct: 249 PPEARIPKKRWRLYPFKNDEVLPVMYIHRQSAYLLGRHRRIADIPIDHPSCSKQHAVFQY 308

Query: 77  HK-----------HLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTRAYT 125
                           + ++IDL S +GTFL + R+EP +  ++     + FG S+R Y 
Sbjct: 309 RLVEYTRADGTVGRRVKPYIIDLGSGNGTFLNNKRIEPQRYYELKEKDVLKFGFSSREYV 368

Query: 126 LREKPQTLPSAVKGDEKMGGEDDEL 150
           L  +        + D++   E++E+
Sbjct: 369 LLHESSDTSEIDRKDDEDEEEEEEV 393


>gi|155722990 solute carrier family 4 (anion exchanger), member 1,
           adaptor protein [Homo sapiens]
          Length = 796

 Score = 65.5 bits (158), Expect = 7e-11
 Identities = 40/125 (32%), Positives = 57/125 (45%), Gaps = 10/125 (8%)

Query: 12  PLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDHQSCSRVH 71
           P +  P W G       L+ +KG  ++    +    Y LFGR    CD  ++H S SR H
Sbjct: 152 PPYQEPPWGGPATAPYSLETLKGGTILGTRSLKGTSYCLFGRLSG-CDVCLEHPSVSRYH 210

Query: 72  AALVYH---------KHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGASTR 122
           A L +           +    +L DL STHGTFL   R+ P    ++ +   V FG STR
Sbjct: 211 AVLQHRASGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFGGSTR 270

Query: 123 AYTLR 127
            + L+
Sbjct: 271 LFILQ 275


>gi|163644261 hypothetical protein LOC283638 isoform 1 [Homo
           sapiens]
          Length = 1554

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 3/120 (2%)

Query: 58  CDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSF 117
           C+  +  +S  + HA + Y +     ++ DL S +GTF+  +R+   K   + ++  + F
Sbjct: 30  CELMLQSRSVDKQHAVINYDQDRDEHWVKDLGSLNGTFVNDMRIPDQKYVTLKLNDVIRF 89

Query: 118 GASTRAYTLREKPQTLP-SAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKR 176
           G  +  Y L      +P  A+K ++        +KGL   P+    L   T +  A N R
Sbjct: 90  GYDSNMYVLERVQHRVPEEALKHEKYTSQLQVSVKGL--APKRSEALPEHTPYCEASNPR 147


>gi|109255230 centrosomal protein 170kDa isoform beta [Homo sapiens]
          Length = 1486

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 35/164 (21%), Positives = 62/164 (37%), Gaps = 13/164 (7%)

Query: 56  DLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTV 115
           D C+  +  +S  + HA + Y        + DL S +GTF+  +R+       + ++  +
Sbjct: 28  DDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKL 87

Query: 116 SFGASTRAYTLREKPQTLPSAVKGDEKM---------GGEDDELKGLLGLPEEETELDNL 166
            FG  T  +T+ +    +P      EK            E +  K       +    D  
Sbjct: 88  RFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAA 147

Query: 167 TEFNTAHNKRISTLTIEEGNLDIQ-RPKRKRKNSRVTFSEDDEI 209
           TE     +K    L  EE  +DI   P+      + ++  DDE+
Sbjct: 148 TE---VQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEV 188


>gi|109255228 centrosomal protein 170kDa isoform alpha [Homo
           sapiens]
          Length = 1584

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 35/164 (21%), Positives = 62/164 (37%), Gaps = 13/164 (7%)

Query: 56  DLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTV 115
           D C+  +  +S  + HA + Y        + DL S +GTF+  +R+       + ++  +
Sbjct: 28  DDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKL 87

Query: 116 SFGASTRAYTLREKPQTLPSAVKGDEKM---------GGEDDELKGLLGLPEEETELDNL 166
            FG  T  +T+ +    +P      EK            E +  K       +    D  
Sbjct: 88  RFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAA 147

Query: 167 TEFNTAHNKRISTLTIEEGNLDIQ-RPKRKRKNSRVTFSEDDEI 209
           TE     +K    L  EE  +DI   P+      + ++  DDE+
Sbjct: 148 TE---VQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEV 188


>gi|109255232 centrosomal protein 170kDa isoform gamma [Homo
           sapiens]
          Length = 1460

 Score = 39.7 bits (91), Expect = 0.004
 Identities = 35/164 (21%), Positives = 62/164 (37%), Gaps = 13/164 (7%)

Query: 56  DLCDFTIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTV 115
           D C+  +  +S  + HA + Y        + DL S +GTF+  +R+       + ++  +
Sbjct: 28  DDCELMLQSRSVDKQHAVINYDASTDEHLVKDLGSLNGTFVNDVRIPEQTYITLKLEDKL 87

Query: 116 SFGASTRAYTLREKPQTLPSAVKGDEKM---------GGEDDELKGLLGLPEEETELDNL 166
            FG  T  +T+ +    +P      EK            E +  K       +    D  
Sbjct: 88  RFGYDTNLFTVVQGEMRVPEEALKHEKFTIQLQLSQKSSESELSKSASAKSIDSKVADAA 147

Query: 167 TEFNTAHNKRISTLTIEEGNLDIQ-RPKRKRKNSRVTFSEDDEI 209
           TE     +K    L  EE  +DI   P+      + ++  DDE+
Sbjct: 148 TE---VQHKTTEALKSEEKAMDISAMPRGTPLYGQPSWWGDDEV 188


>gi|39725952 angiogenic factor VG5Q [Homo sapiens]
          Length = 714

 Score = 35.0 bits (79), Expect = 0.10
 Identities = 51/219 (23%), Positives = 83/219 (37%), Gaps = 22/219 (10%)

Query: 24  PPGLHLDVVKGDKLI--EKLIIDEKKYYLFGRNPDL-CDFTIDHQSCSRVHAALVYHKHL 80
           PP + + V++   L      II        GR  D+     I     S+ HA + +   L
Sbjct: 407 PPCIRVIVIRSPVLQIGSLFIITAVNPATIGREKDMEHTLRIPEVGVSKFHAEIYFDHDL 466

Query: 81  KRVFLIDLNSTHGTFL-GHIRLEPH---KPQQIPIDSTVSFGASTRAYTLREKPQTL--- 133
           +   L+D  S +GT + G   L+P     P  +     V  G +  ++ +     T    
Sbjct: 467 QSYVLVDQGSQNGTIVNGKQILQPKTKCDPYVLEHGDEVKIGETVLSFHIHPGSDTCDGC 526

Query: 134 -PSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDIQRP 192
            P  V+   ++  +D+   G   L +EE EL+   E      K     T  E    ++ P
Sbjct: 527 EPGQVRAHLRLDKKDESFVGPT-LSKEEKELERRKELKKIRVKYGLQNTEYEDEKTLKNP 585

Query: 193 K--------RKRKNSRVTFSEDD--EIINPEDVDPSVGR 221
           K        R++  S  TF  DD    ++ E  D + GR
Sbjct: 586 KYKDRAGKRREQVGSEGTFQRDDAPASVHSEITDSNKGR 624


>gi|5031937 calcium binding and coiled-coil domain 2 [Homo sapiens]
          Length = 446

 Score = 34.7 bits (78), Expect = 0.13
 Identities = 42/172 (24%), Positives = 77/172 (44%), Gaps = 24/172 (13%)

Query: 121 TRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTL 180
           T    L+E+ Q + S    +EKMG   D+L+  L    +E E++ L + +    +++  L
Sbjct: 207 TELLQLKEQNQKMSSE---NEKMGIRVDQLQAQLS--TQEKEMEKLVQGDQDKTEQLEQL 261

Query: 181 TIEEGNLDI----QRPKRKR--------KNSRVTFSEDDEIINPEDVDPSVGRFRNMVQT 228
             E  +L +    QR  +K+        K +  T  +  + +  E+ D S     N +  
Sbjct: 262 KKENDHLFLSLTEQRKDQKKLEQTVEQMKQNETTAMKKQQELMDENFDLSKRLSENEIIC 321

Query: 229 AVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLP---PTHSEAGSQ 277
             +  +K+R+EG   L L+   SR +   ++ G  +  LP   PT  E G++
Sbjct: 322 NALQRQKERLEGENDL-LKRENSRLL---SYMGLDFNSLPYQVPTSDEGGAR 369


>gi|55743112 NAD kinase [Homo sapiens]
          Length = 446

 Score = 32.7 bits (73), Expect = 0.50
 Identities = 19/69 (27%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 276 SQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKY 335
           S P G    A   G  M +PN+ P + +TP+ P +++  P   PA    + +  P+ +  
Sbjct: 319 STPTGSTAYAAAAGASMIHPNV-PAIMITPICPHSLSFRPIVVPAGVELKIMLSPEARNT 377

Query: 336 AKEAWPGKK 344
           A  ++ G+K
Sbjct: 378 AWVSFDGRK 386


>gi|29826335 eukaryotic translation initiation factor 2 beta [Homo
           sapiens]
          Length = 333

 Score = 32.7 bits (73), Expect = 0.50
 Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 34/114 (29%)

Query: 131 QTLPSAVKGDEKMGGEDDELKGLLGLPEEET-------ELDNLTEFNTAHNKR------- 176
           +T PS  K  E    ED +L+      EE+T       +LD+L  FN    K+       
Sbjct: 35  ETQPSETKEVEPEPTEDKDLEA----DEEDTRKKDASDDLDDLNFFNQKKKKKKTKKIFD 90

Query: 177 -------ISTLTIE---------EGNLDIQRPKRKRKNSRVTFSEDDEIINPED 214
                  +  L IE         E +LDI    +K+K   V F ++DEI+  ++
Sbjct: 91  IDEAEEGVKDLKIESDVQEPTEPEDDLDIMLGNKKKKKKNVKFPDEDEILEKDE 144


>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
           sapiens]
          Length = 870

 Score = 32.3 bits (72), Expect = 0.65
 Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 9/154 (5%)

Query: 154 LGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDI---QRPKRKRKNSRVTFSEDDEII 210
           L LP  E  +    E    ++  +  +T++  ++++     P  + ++S+    ++  I 
Sbjct: 273 LTLPNHEVSVQPPGEDQAYYH--LPNITVKPADVEVTITSEPTNETESSQA--QQETPIQ 328

Query: 211 NPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPT 270
            PE+V+PS  +    ++  V P++ +         ++ S S R    + +     G PP 
Sbjct: 329 FPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPE 388

Query: 271 HSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLT 304
           H E    P G H T  +    +      PDV LT
Sbjct: 389 HHEVTVSPPGHHQTHHLDSPSVSVK--PPDVQLT 420


>gi|29336043 caytaxin [Homo sapiens]
          Length = 371

 Score = 32.3 bits (72), Expect = 0.65
 Identities = 22/65 (33%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query: 153 LLGLPEEETEL-DNLTEFNTAHNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIIN 211
           LLG P E+T    N   FN AH KR  TL   E N+ + + +    +     + DD  IN
Sbjct: 36  LLGSPVEDTSSPPNTLNFNGAHRKR-KTLVAPEINISLDQSEGSLLSDDFLDTPDDLDIN 94

Query: 212 PEDVD 216
            +D++
Sbjct: 95  VDDIE 99


>gi|239742740 PREDICTED: hypothetical protein XP_002342615 [Homo
           sapiens]
          Length = 159

 Score = 32.0 bits (71), Expect = 0.85
 Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 9/95 (9%)

Query: 237 RVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGI--HGTALIGGL---- 290
           R  GPG+L L   GS R+     +   +G   P  S  GS   G+  HG A    L    
Sbjct: 44  RAPGPGTLFLLGKGSPRLAQHPAARRSHGSRLPRTS--GSPEEGVSGHGPAAAASLPRAQ 101

Query: 291 -PMPYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNP 324
            P P P+ A    L   +P   ++  A +PA   P
Sbjct: 102 VPTPPPSHAQPQPLQRTLPPPTSLPAALDPAPSRP 136


>gi|7706621 T-cell leukemia homeobox 2 [Homo sapiens]
          Length = 284

 Score = 32.0 bits (71), Expect = 0.85
 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 8/62 (12%)

Query: 242 GSLGLEESGSRRMQNFAFSGGLY--------GGLPPTHSEAGSQPHGIHGTALIGGLPMP 293
           G LGL   G    +N AFSGG +        G L P    +G  P G+        LP+P
Sbjct: 33  GGLGLGRGGQGHGENGAFSGGYHGASGYGPAGSLAPLPGSSGVGPGGVIRVPAHRPLPVP 92

Query: 294 YP 295
            P
Sbjct: 93  PP 94


>gi|223468693 hypothetical protein LOC100130361 [Homo sapiens]
          Length = 514

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 18/138 (13%)

Query: 217 PSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGS 276
           P  GRF       + PV ++   G     LE+S  ++MQ+ A+            + AG+
Sbjct: 253 PVPGRFLTSAPRGLTPVAERPAVGE----LEDSPQKKMQSRAWGKVEVRPSCSGAAAAGA 308

Query: 277 QPHGIHGTALIGGLPMPYPNLAPDVDLT-----PVVPSAVNMNPAPNPAVYNPEAVNEP- 330
            P G+    + GG      +L     L      P     ++  P P PA + P +   P 
Sbjct: 309 LPQGLSRRKMAGGKK----SLGGASQLALGRGFPACGERLSAAP-PEPATFPPFSGVRPQ 363

Query: 331 ---KKKKYAKEAWPGKKP 345
              KK +  K + PGKKP
Sbjct: 364 GMSKKPQKPKHSSPGKKP 381


>gi|223468690 hypothetical protein LOC100132994 [Homo sapiens]
          Length = 514

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 36/138 (26%), Positives = 55/138 (39%), Gaps = 18/138 (13%)

Query: 217 PSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGS 276
           P  GRF       + PV ++   G     LE+S  ++MQ+ A+            + AG+
Sbjct: 253 PVPGRFLTSAPRGLTPVAERPAVGE----LEDSPQKKMQSRAWGKVEVRPSCSGAAAAGA 308

Query: 277 QPHGIHGTALIGGLPMPYPNLAPDVDLT-----PVVPSAVNMNPAPNPAVYNPEAVNEP- 330
            P G+    + GG      +L     L      P     ++  P P PA + P +   P 
Sbjct: 309 LPQGLSRRKMAGGKK----SLGGASQLALGRGFPACGERLSAAP-PEPATFPPFSGVRPQ 363

Query: 331 ---KKKKYAKEAWPGKKP 345
              KK +  K + PGKKP
Sbjct: 364 GMSKKPQKPKHSSPGKKP 381


>gi|44681484 cell division cycle associated 2 [Homo sapiens]
          Length = 1023

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 164 DNLTEFNTAHNKRISTL--------TIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDV 215
           +NL + +  H   IS L          +E N +       RK  RVTF ED   ++PE  
Sbjct: 348 NNLYDDDGTHPSLISNLPNCCKEKEAEDEENFEAPAFLNMRKRKRVTFGED---LSPEVF 404

Query: 216 DPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEES 249
           D S+      ++    PV KK   G  SL LE+S
Sbjct: 405 DESLPA-NTPLRKGGTPVCKKDFSGLSSLLLEQS 437


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 2/68 (2%)

Query: 282  HGTAL-IGGLPMPYPNLAPDVDLTPVVPS-AVNMNPAPNPAVYNPEAVNEPKKKKYAKEA 339
            HGT   +   P P P     V     +PS +   +PAP+PA   P A+ +P     +  A
Sbjct: 1264 HGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGA 1323

Query: 340  WPGKKPTP 347
             P K P+P
Sbjct: 1324 SPAKPPSP 1331


>gi|28372497 ubiquitin protein ligase E3 component n-recognin 1
           [Homo sapiens]
          Length = 1749

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 4/45 (8%)

Query: 30  DVVKGDKLIEKLIIDEKKYYLFGRNPDLCDFTIDH----QSCSRV 70
           D+ K ++ ++  I    ++YLFG +PD+C   + H    Q C RV
Sbjct: 58  DLEKQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGAFQLCGRV 102


>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
           sapiens]
          Length = 1634

 Score = 31.2 bits (69), Expect = 1.5
 Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 9/154 (5%)

Query: 154 LGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDI---QRPKRKRKNSRVTFSEDDEII 210
           L LP  E  +    E    ++  +  +T++  ++++     P  + ++S+    ++  I 
Sbjct: 273 LTLPNHEVSVQPPGEDQAYYH--LPNITVKPADVEVTITSEPTNETESSQA--QQETPIQ 328

Query: 211 NPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPT 270
            PE+V+PS  +    ++  V P++ +         ++ S S R    + +     G PP 
Sbjct: 329 FPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPE 388

Query: 271 HSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLT 304
           H E    P G H T  +    +      PDV LT
Sbjct: 389 HHEVTVSPPGHHQTHHLASPSVSVK--PPDVQLT 420


>gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 1/52 (1%)

Query: 232  PVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHG 283
            P  +  V  PG+LG  +S   R       G L+G   P H +  S P  +HG
Sbjct: 1112 PALRAIVPTPGTLG-RDSSPGRTSIIPSPGALHGDRSPAHLDIASTPGALHG 1162


>gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 1/52 (1%)

Query: 232  PVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHG 283
            P  +  V  PG+LG  +S   R       G L+G   P H +  S P  +HG
Sbjct: 1112 PALRAIVPTPGTLG-RDSSPGRTSIIPSPGALHGDRSPAHLDIASTPGALHG 1162


>gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2028

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 1/52 (1%)

Query: 232  PVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHG 283
            P  +  V  PG+LG  +S   R       G L+G   P H +  S P  +HG
Sbjct: 1080 PALRAIVPTPGTLG-RDSSPGRTSIIPSPGALHGDRSPAHLDIASTPGALHG 1130


>gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1934

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 17/52 (32%), Positives = 23/52 (44%), Gaps = 1/52 (1%)

Query: 232  PVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHG 283
            P  +  V  PG+LG  +S   R       G L+G   P H +  S P  +HG
Sbjct: 986  PALRAIVPTPGTLG-RDSSPGRTSIIPSPGALHGDRSPAHLDIASTPGALHG 1036


>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular
           protein isoform 1 [Homo sapiens]
          Length = 1635

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 9/154 (5%)

Query: 154 LGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDI---QRPKRKRKNSRVTFSEDDEII 210
           L LP  E  +    E    ++  +  +T++  ++++     P  + ++S+    ++  I 
Sbjct: 273 LTLPNHEVSVQPPGEDQAYYH--LPNITVKPADVEVTITSEPTNETESSQA--QQETPIQ 328

Query: 211 NPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPT 270
            PE+V+PS  +    ++  V P++ +         ++ S S R    + +     G PP 
Sbjct: 329 FPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPE 388

Query: 271 HSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLT 304
           H E    P G H T  +    +      PDV LT
Sbjct: 389 HHEVTVSPPGHHQTHHLASPSVSVK--PPDVQLT 420


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular
           protein isoform 2 [Homo sapiens]
          Length = 1700

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 33/154 (21%), Positives = 64/154 (41%), Gaps = 9/154 (5%)

Query: 154 LGLPEEETELDNLTEFNTAHNKRISTLTIEEGNLDI---QRPKRKRKNSRVTFSEDDEII 210
           L LP  E  +    E    ++  +  +T++  ++++     P  + ++S+    ++  I 
Sbjct: 273 LTLPNHEVSVQPPGEDQAYYH--LPNITVKPADVEVTITSEPTNETESSQA--QQETPIQ 328

Query: 211 NPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPT 270
            PE+V+PS  +    ++  V P++ +         ++ S S R    + +     G PP 
Sbjct: 329 FPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPE 388

Query: 271 HSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLT 304
           H E    P G H T  +    +      PDV LT
Sbjct: 389 HHEVTVSPPGHHQTHHLASPSVSVK--PPDVQLT 420


>gi|156546910 BRAF35/HDAC2 complex isoform b [Homo sapiens]
          Length = 634

 Score = 30.8 bits (68), Expect = 1.9
 Identities = 13/38 (34%), Positives = 19/38 (50%)

Query: 293 PYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEP 330
           P PN  P V   PV  + + + PAP P +  P+ +  P
Sbjct: 227 PRPNFLPQVRPKPVAQNNIPIAPAPPPMLAAPQLIQRP 264


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.135    0.404 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,873,425
Number of Sequences: 37866
Number of extensions: 924405
Number of successful extensions: 2328
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 63
Number of HSP's that attempted gapping in prelim test: 2280
Number of HSP's gapped (non-prelim): 115
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.