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Search of human proteins with 6912242
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|6912242 adaptor protein, phosphotyrosine interaction, PH
domain and leucine zipper containing 1 [Homo sapiens]
(709 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|6912242 adaptor protein, phosphotyrosine interaction, PH doma... 1396 0.0
gi|24586663 adaptor protein, phosphotyrosine interaction, PH dom... 677 0.0
gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH doma... 110 4e-24
gi|187608516 centaurin, beta 2 [Homo sapiens] 106 8e-23
gi|50843948 Rho GTPase activating protein 10 [Homo sapiens] 99 2e-20
gi|7661880 centaurin beta1 [Homo sapiens] 86 2e-16
gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo s... 83 8e-16
gi|208022687 GTPase regulator associated with the focal adhesion... 82 1e-15
gi|7662208 GTPase regulator associated with the focal adhesion k... 82 1e-15
gi|4505507 oligophrenin 1 [Homo sapiens] 80 7e-15
gi|46094081 development and differentiation enhancing factor 1 [... 66 1e-10
gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domai... 64 6e-10
gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain ... 64 6e-10
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom... 60 9e-09
gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens] 42 0.003
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 39 0.013
gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo ... 39 0.022
gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo... 39 0.022
gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens] 38 0.037
gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens] 38 0.037
gi|124249396 coiled-coil domain containing 30 [Homo sapiens] 37 0.048
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 37 0.048
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.063
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 37 0.063
gi|122937227 U2-associated SR140 protein [Homo sapiens] 37 0.063
gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens] 37 0.063
gi|118498368 kinectin 1 isoform c [Homo sapiens] 37 0.082
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 37 0.082
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 37 0.082
gi|16262452 cingulin [Homo sapiens] 36 0.11
>gi|6912242 adaptor protein, phosphotyrosine interaction, PH domain
and leucine zipper containing 1 [Homo sapiens]
Length = 709
Score = 1396 bits (3614), Expect = 0.0
Identities = 709/709 (100%), Positives = 709/709 (100%)
Query: 1 MPGIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHL 60
MPGIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHL
Sbjct: 1 MPGIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHL 60
Query: 61 TSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE 120
TSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE
Sbjct: 61 TSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE 120
Query: 121 RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMH 180
RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMH
Sbjct: 121 RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMH 180
Query: 181 YFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREM 240
YFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREM
Sbjct: 181 YFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREM 240
Query: 241 DSDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTWDRQ 300
DSDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTWDRQ
Sbjct: 241 DSDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTWDRQ 300
Query: 301 FYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAESK 360
FYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAESK
Sbjct: 301 FYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAESK 360
Query: 361 KDHEEWICTINNISKQIYLSENPEETAARVNQSALEAVTPSPSFQQRHESLRPAAGQSRP 420
KDHEEWICTINNISKQIYLSENPEETAARVNQSALEAVTPSPSFQQRHESLRPAAGQSRP
Sbjct: 361 KDHEEWICTINNISKQIYLSENPEETAARVNQSALEAVTPSPSFQQRHESLRPAAGQSRP 420
Query: 421 PTARTSSSGSLGSESTNLAALSLDSLVAPDTPIQFDIISPVCEDQPGQAKAFGQGGRRTN 480
PTARTSSSGSLGSESTNLAALSLDSLVAPDTPIQFDIISPVCEDQPGQAKAFGQGGRRTN
Sbjct: 421 PTARTSSSGSLGSESTNLAALSLDSLVAPDTPIQFDIISPVCEDQPGQAKAFGQGGRRTN 480
Query: 481 PFGESGGSTKSETEDSILHQLFIVRFLGSMEVKSDDHPDVVYETMRQILAARAIHNIFRM 540
PFGESGGSTKSETEDSILHQLFIVRFLGSMEVKSDDHPDVVYETMRQILAARAIHNIFRM
Sbjct: 481 PFGESGGSTKSETEDSILHQLFIVRFLGSMEVKSDDHPDVVYETMRQILAARAIHNIFRM 540
Query: 541 TESHLLVTCDCLKLIDPQTQVTRLTFPLPCVVLYATHQENKRLFGFVLRTSSGRSESNLS 600
TESHLLVTCDCLKLIDPQTQVTRLTFPLPCVVLYATHQENKRLFGFVLRTSSGRSESNLS
Sbjct: 541 TESHLLVTCDCLKLIDPQTQVTRLTFPLPCVVLYATHQENKRLFGFVLRTSSGRSESNLS 600
Query: 601 SVCYIFESNNEGEKICDSVGLAKQIALHAELDRRASEKQKEIERVKEKQQKELNKQKQIE 660
SVCYIFESNNEGEKICDSVGLAKQIALHAELDRRASEKQKEIERVKEKQQKELNKQKQIE
Sbjct: 601 SVCYIFESNNEGEKICDSVGLAKQIALHAELDRRASEKQKEIERVKEKQQKELNKQKQIE 660
Query: 661 KDLEEQSRLIAASSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRESEA 709
KDLEEQSRLIAASSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRESEA
Sbjct: 661 KDLEEQSRLIAASSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRESEA 709
>gi|24586663 adaptor protein, phosphotyrosine interaction, PH domain
and leucine zipper containing 2 [Homo sapiens]
Length = 664
Score = 677 bits (1748), Expect = 0.0
Identities = 342/627 (54%), Positives = 459/627 (73%), Gaps = 14/627 (2%)
Query: 1 MPGIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHL 60
MP +DKL +EE L+DSPQTRSLL VFEEDA +++Y NQL QAM R+Y AQNE+ AT
Sbjct: 1 MPAVDKLLLEEALQDSPQTRSLLSVFEEDAGTLTDYTNQLLQAMQRVYGAQNEMCLATQQ 60
Query: 61 TSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE 120
SK L YEKQ F LG DE + STL FSKV+DEL+ H L+ QLAD M+ PI QF+E
Sbjct: 61 LSKQLLAYEKQNFALGKGDEEVISTLHYFSKVVDELNLLHTELAKQLADTMVLPIIQFRE 120
Query: 121 RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMH 180
+DL E+ TLK++F +ASN+HD ++ +YSRL KK+EN+KVK EV ++V +R+KQH + +
Sbjct: 121 KDLTEVSTLKDLFGLASNEHDLSMAKYSRLPKKKENEKVKTEVGKEVAAARRKQHLSSLQ 180
Query: 181 YFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREM 240
Y+CALN LQY+K++A++EP++G+ QI+FFK G+E +++++ FL+++ VQ+++ E+
Sbjct: 181 YYCALNALQYRKQMAMMEPMIGFAHGQINFFKKGAEMFSKRMDSFLSSVADMVQSIQVEL 240
Query: 241 DSDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTWDRQ 300
+++ E M+ + ++L + +Y PD D +NRNL +KAGYLN RNKTGLV++TW+R
Sbjct: 241 EAEAEKMRVSQQELLSVDESVYTPDSDVAAPQINRNLIQKAGYLNLRNKTGLVTTTWERL 300
Query: 301 FYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAESK 360
++FTQGGNLM Q RG VAGGL D+DNCSVMAVDCEDRRYCFQIT+ +GK ILQAES+
Sbjct: 301 YFFTQGGNLMCQPRGAVAGGLIQDLDNCSVMAVDCEDRRYCFQITTPNGKSGIILQAESR 360
Query: 361 KDHEEWICTINNISKQIYLSENPEETAARVNQSALEAVTPSPSFQQRHESLRPAAGQSRP 420
K++EEWIC INNIS+QIYL++NPE A ++NQ+AL+AVTP SF ++ ES P+ Q+
Sbjct: 361 KENEEWICAINNISRQIYLTDNPEAVAIKLNQTALQAVTPITSFGKKQESSCPS--QNLK 418
Query: 421 PTARTSSSGSLGSESTNLAALSLDSLVAPDTPIQFDIISPVCE--DQPGQAKAFGQGGRR 478
+ + + + ++T + + L+AP TPIQFDI+ P E DQ +G RR
Sbjct: 419 NSEMENENDKIVPKAT-ASLPEAEELIAPGTPIQFDIVLPATEFLDQ-------NRGSRR 470
Query: 479 TNPFGESGGSTKSETEDSILHQLFIVRFLGSMEVKSDDHPDVVYETMRQILAARAIHNIF 538
TNPFGE+ + E EDS+L Q+FIVRFLGSM VK+D +V+YE MRQ+LAARAIHNIF
Sbjct: 471 TNPFGETEDESFPEAEDSLLQQMFIVRFLGSMAVKTDSTTEVIYEAMRQVLAARAIHNIF 530
Query: 539 RMTESHLLVTCDCLKLIDPQTQVTRLTFPLPCVVLYATHQENKRLFGFVLRTSSGRSESN 598
RMTESHL+VT L+LIDPQTQV+R F L V +A HQENKRL GFV+R E +
Sbjct: 531 RMTESHLMVTSQSLRLIDPQTQVSRANFELTSVTQFAAHQENKRLVGFVIRVPESTGEES 590
Query: 599 LSSVCYIFESNNEGEKICDSVGLAKQI 625
LS+ YIFESN+EGEKIC ++ L K+I
Sbjct: 591 LST--YIFESNSEGEKICYAINLGKEI 615
>gi|218563749 ArfGAP with coiled-coil, ankyrin repeat and PH domains
3 [Homo sapiens]
Length = 834
Score = 110 bits (275), Expect = 4e-24
Identities = 104/450 (23%), Positives = 203/450 (45%), Gaps = 30/450 (6%)
Query: 10 EETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTSKLLKEYE 69
EE ++DSP+ R+ + E D I +++L + + +A + + L +++
Sbjct: 6 EECVKDSPRFRATIDEVETDVVEIEAKLDKLVKLCSGMVEAGKAYVSTSRLFVSGVRDLS 65
Query: 70 KQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTL 129
+Q D V+S LQ+F+ + E+ + H +L Q ++ + F + D+++
Sbjct: 66 QQC----QGDTVISECLQRFADSLQEVVNYHMILFDQAQRSVRQQLQSFVKEDVRKFKET 121
Query: 130 KEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCALNTLQ 189
K+ F D + ++ R ++ + R ++ E T + +RK + Y +N LQ
Sbjct: 122 KKQFDKVREDLELSLVRNAQAPRHRPHEVE--EATGALTLTRKCFRHLALDYVLQINVLQ 179
Query: 190 YKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQ 249
KKK +L+ +L +M AQ SFF+ G +L QL+ ++ + + + +DS +E +
Sbjct: 180 AKKKFEILDSMLSFMHAQSSFFQQG-YSLLHQLDPYMKKLAAELDQL--VIDSAVEKREM 236
Query: 250 TIEDLEVASDPL---YVPDPDPTKFPVNR-NLTRKAGYLNARNKTGLVSSTWDRQFYFTQ 305
+ + L + D +F V+ + GYL R TW+R+++ Q
Sbjct: 237 ERKHAAIQQRTLLQDFSYDESKVEFDVDAPSGVVMEGYLFKRASNAF--KTWNRRWFSIQ 294
Query: 306 GGNLMSQAR-GDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAESKKDHE 364
L+ Q + D + D+ CSV + +RR+CF++ S KS +LQA+S+K +
Sbjct: 295 NSQLVYQKKLKDALTVVVDDLRLCSVKPCEDIERRFCFEVLS--PTKSCMLQADSEKLRQ 352
Query: 365 EWICTINNISKQIYLSENPE-------ETAARVNQSALEAVTPSPSFQQRHESLRPAAGQ 417
W+ + Y E+P+ + A + S++++ T + + ES+ Q
Sbjct: 353 AWVQAVQASIASAY-RESPDSCYSERLDRTASPSTSSIDSATDTRERGVKGESVL----Q 407
Query: 418 SRPPTARTSSSGSLGSESTNLAALSLDSLV 447
A S G G A+++L L+
Sbjct: 408 RVQSVAGNSQCGDCGQPDPRWASINLGVLL 437
>gi|187608516 centaurin, beta 2 [Homo sapiens]
Length = 778
Score = 106 bits (264), Expect = 8e-23
Identities = 89/386 (23%), Positives = 176/386 (45%), Gaps = 34/386 (8%)
Query: 10 EETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTSKLLKEYE 69
EE L+DSP+ R+ L E D + +++L + + D A +++
Sbjct: 8 EECLKDSPRFRAALEEVEGDVAELELKLDKLVKLCIAMIDTGKAFCVANKQFMNGIRDLA 67
Query: 70 KQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTL 129
+ +D V+ ++L +FS + E+ + H +L Q ++ + F + DL++
Sbjct: 68 QY----SSNDAVVETSLTKFSDSLQEMINFHTILFDQTQRSIKAQLQNFVKEDLRKFKDA 123
Query: 130 KEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCALNTLQ 189
K+ F+ S + + A+ + +++ + ++++ E T + +RK + Y +N LQ
Sbjct: 124 KKQFEKVSEEKENALVKNAQVQRNKQHE--VEEATNILTATRKCFRHIALDYVLQINVLQ 181
Query: 190 YKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNV-------RREMDS 242
K++ +L+ +L +M A ++FF G + L +L ++ ++G + + +REM+
Sbjct: 182 SKRRSEILKSMLSFMYAHLAFFHQGYD-LFSELGPYMKDLGAQLDRLVVDAAKEKREMEQ 240
Query: 243 DIETMQQTIEDLEVASDPLYVPDPDPTKFPVN---RNLTRKAGYLNARNKTGLVSSTWDR 299
T+QQ +D D +K N N GYL R TW+R
Sbjct: 241 KHSTIQQ--KDF----------SSDDSKLEYNVDAANGIVMEGYLFKRASNAF--KTWNR 286
Query: 300 QFYFTQGGNLMSQAR-GDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAE 358
+++ Q L+ Q + D + D+ C+V + +RR+CF++ S KS +LQA+
Sbjct: 287 RWFSIQNNQLVYQKKFKDNPTVVVEDLRLCTVKHCEDIERRFCFEVVS--PTKSCMLQAD 344
Query: 359 SKKDHEEWICTINNISKQIYLSENPE 384
S+K + WI + Y + E
Sbjct: 345 SEKLRQAWIKAVQTSIATAYREKGDE 370
>gi|50843948 Rho GTPase activating protein 10 [Homo sapiens]
Length = 786
Score = 98.6 bits (244), Expect = 2e-20
Identities = 80/382 (20%), Positives = 166/382 (43%), Gaps = 36/382 (9%)
Query: 3 GIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTS 62
G+ L + DSP R + E + + ++ +L + + A LS A +
Sbjct: 2 GLQPLEFSDCYLDSPWFRERIRAHEAELERTNKFIKELIKDGKNLIAATKSLSVAQRKFA 61
Query: 63 KLLKEYEKQRF--PLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE 120
L++++ + + D+ + ++L++FS + L +++ + + ++ P+ +F++
Sbjct: 62 HSLRDFKFEFIGDAVTDDERCIDASLREFSNFLKNLEEQREIMALSVTETLIKPLEKFRK 121
Query: 121 RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQH--QTM 178
L + K+ F + + + I+++ LS K+++ ++ D+ + +QH +
Sbjct: 122 EQLGAVKEEKKKFDKETEKNYSLIDKHLNLSAKKKDSHLQ---EADIQVEQNRQHFYELS 178
Query: 179 MHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRR 238
+ Y C L +Q +KK +EP+L + Q +F+ G E L + + + ++QN R
Sbjct: 179 LEYVCKLQEIQERKKFEFVEPMLSFFQGMFTFYHQGHE-LAKDFNHYKMELQINIQNTRN 237
Query: 239 EMD---SDIETMQQTIEDLE---------VASDPLYVPDPDPTKFPVNRNLTRKAGYLNA 286
+ S++E + I A LYV + P F + + Y A
Sbjct: 238 RFEGTRSEVEELMNKIRQNPKDHKRASQFTAEGYLYVQEKRPAPFG-SSWVKHYCMYRKA 296
Query: 287 RNKTGLVSSTWDRQFYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITS 346
K ++ F GG L GD G + C+ D DRR+CF I +
Sbjct: 297 AKKFNMI------PFEHRSGGKL-----GD---GEVFFLKECTKRHTDSIDRRFCFDIEA 342
Query: 347 FDGKKSSI-LQAESKKDHEEWI 367
D S+ +QA S+++ ++W+
Sbjct: 343 ADRPGVSLTMQAFSEEERKQWL 364
>gi|7661880 centaurin beta1 [Homo sapiens]
Length = 740
Score = 85.5 bits (210), Expect = 2e-16
Identities = 90/431 (20%), Positives = 183/431 (42%), Gaps = 33/431 (7%)
Query: 6 KLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTSKLL 65
KL EE L+DSP+ R+ + + E + + + + +L + + ++ AA+ +
Sbjct: 4 KLDFEECLKDSPRFRASIELVEAEVSELETRLEKLLKLGTGLLESGRHYLAASRAFVVGI 63
Query: 66 KEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKE 125
+ + LG + +M+ L++F+ ++ HA L + I + L+
Sbjct: 64 CDLAR----LGPPEPMMAECLEKFTVSLNHKLDSHAELLDATQHTLQQQIQTLVKEGLRG 119
Query: 126 ILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCAL 185
+ F + +AA+ + + ++R + E + T+R + Y +
Sbjct: 120 FREARRDFWRGAESLEAALTHNAEVPRRRAQEAE--EAGAALRTARAGYRGRALDYALQI 177
Query: 186 NTLQYKKKIALLEPLLGYMQAQISFFKMGSE---NLNEQLEEFLANIGTSVQNVRREMDS 242
N ++ K+K ++E +L ++AQ + F+ G E L++ +E A + V N RE
Sbjct: 178 NVIEDKRKFDIMEFVLRLVEAQATHFQQGHEELSRLSQYRKELGAQLHQLVLNSARE-KR 236
Query: 243 DIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTWDRQFY 302
D+E ++ E+ + +P+P+ L + G+L R TW R+++
Sbjct: 237 DMEQRHVLLKQKELGGE-----EPEPSLREGPGGLVME-GHLFKRASNAF--KTWSRRWF 288
Query: 303 FTQGGNLMSQAR-GDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSILQAESKK 361
Q L+ Q + D + D+ C+V +RR+CF++ S KS +LQA+S++
Sbjct: 289 TIQSNQLVYQKKYKDPVTVVVDDLRLCTVKLCPDSERRFCFEVVS--TSKSCLLQADSER 346
Query: 362 DHEEWICTINNISKQIYLSENPEETAARVNQSALEAVTPSPSFQQRHESLRPAAGQSRPP 421
+ W+ + + A+ +Q+ L+ P H ++ AA
Sbjct: 347 LLQLWVSAVQS------------SIASAFSQARLDDSPRGPGQGSGHLAIGSAATLGSGG 394
Query: 422 TARTSSSGSLG 432
AR G +G
Sbjct: 395 MARGREPGGVG 405
>gi|221307575 Rho-type GTPase-activating protein FLJ32810 [Homo
sapiens]
Length = 874
Score = 83.2 bits (204), Expect = 8e-16
Identities = 74/379 (19%), Positives = 169/379 (44%), Gaps = 28/379 (7%)
Query: 3 GIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTS 62
G+ L ++ DSP R L E + + ++ +L + + A LS A S
Sbjct: 2 GLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFS 61
Query: 63 KLLKEYEKQRF-PLGGDDEV-MSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE 120
+ L++++ + DDE+ ++ +L++F++++ + L D ++ P+ +F++
Sbjct: 62 QSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRK 121
Query: 121 RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMH 180
+ K+ F S + + + ++ LS K++ ++ E + + ++ +
Sbjct: 122 EQIGAAKDGKKKFDKESEKYYSILEKHLNLSAKKKESHLQ-EADTQIDREHQNFYEASLE 180
Query: 181 YFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREM 240
Y + +Q KKK +EPLL ++Q +F+ G E L ++ + + ++QN R
Sbjct: 181 YVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYE-LAQEFAPYKQQLQFNLQNTRNNF 239
Query: 241 DSDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTWDRQ 300
+S + +++ ++ ++ A+ Y P P+++ + GYL + K L TW +
Sbjct: 240 ESTRQEVERLMQRMKSANQD-YRP---PSQWTME-------GYLYVQEKRPL-GFTWIKH 287
Query: 301 F-YFTQGGNLMSQARGDVAGGLAMD-----------IDNCSVMAVDCEDRRYCFQITSFD 348
+ + +G + + ++ M+ + +C D D+R+CF I +
Sbjct: 288 YCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVE 347
Query: 349 GKKSSILQAESKKDHEEWI 367
LQA S+ + + W+
Sbjct: 348 RHGIITLQAFSEANRKLWL 366
>gi|208022687 GTPase regulator associated with the focal adhesion
kinase pp125 isoform b [Homo sapiens]
Length = 759
Score = 82.4 bits (202), Expect = 1e-15
Identities = 72/376 (19%), Positives = 159/376 (42%), Gaps = 27/376 (7%)
Query: 3 GIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTS 62
G+ L + DSP R L E + + ++ +L + + A LS+A +
Sbjct: 2 GLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFA 61
Query: 63 KLLKEYEKQRFPLGGDDEVM--SSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE 120
L E++ Q D+ M + +LQ+F+ V+ L + ++ ++ P+ +F++
Sbjct: 62 DSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRK 121
Query: 121 RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMH 180
+ K+ + + + + ++ LS K++ +++ E V R+ ++ +
Sbjct: 122 EQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQ-EADSQVDLVRQHFYEVSLE 180
Query: 181 YFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREM 240
Y + +Q +K +EPLL ++Q +F+ G E L + +F + S+QN R
Sbjct: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYE-LAKDFGDFKTQLTISIQNTRNRF 239
Query: 241 D---SDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTW 297
+ S++E++ + +++ +PL P GYL + K +S
Sbjct: 240 EGTRSEVESLMKKMKE-----NPLEHKTISPYTME---------GYLYVQEKRHFGTSWV 285
Query: 298 DRQFYFTQGGNLMSQARGDVAGG------LAMDIDNCSVMAVDCEDRRYCFQITSFDGKK 351
+ + ++ D G ++ + +C+ D ++R+CF + + D
Sbjct: 286 KHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPG 345
Query: 352 SSILQAESKKDHEEWI 367
+QA S++D W+
Sbjct: 346 VITMQALSEEDRRLWM 361
>gi|7662208 GTPase regulator associated with the focal adhesion
kinase pp125 isoform a [Homo sapiens]
Length = 814
Score = 82.4 bits (202), Expect = 1e-15
Identities = 72/376 (19%), Positives = 159/376 (42%), Gaps = 27/376 (7%)
Query: 3 GIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTS 62
G+ L + DSP R L E + + ++ +L + + A LS+A +
Sbjct: 2 GLPALEFSDCCLDSPHFRETLKSHEAELDKTNKFIKELIKDGKSLISALKNLSSAKRKFA 61
Query: 63 KLLKEYEKQRFPLGGDDEVM--SSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKE 120
L E++ Q D+ M + +LQ+F+ V+ L + ++ ++ P+ +F++
Sbjct: 62 DSLNEFKFQCIGDAETDDEMCIARSLQEFATVLRNLEDERIRMIENASEVLITPLEKFRK 121
Query: 121 RDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMH 180
+ K+ + + + + ++ LS K++ +++ E V R+ ++ +
Sbjct: 122 EQIGAAKEAKKKYDKETEKYCGILEKHLNLSSKKKESQLQ-EADSQVDLVRQHFYEVSLE 180
Query: 181 YFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREM 240
Y + +Q +K +EPLL ++Q +F+ G E L + +F + S+QN R
Sbjct: 181 YVFKVQEVQERKMFEFVEPLLAFLQGLFTFYHHGYE-LAKDFGDFKTQLTISIQNTRNRF 239
Query: 241 D---SDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTW 297
+ S++E++ + +++ +PL P GYL + K +S
Sbjct: 240 EGTRSEVESLMKKMKE-----NPLEHKTISPYTME---------GYLYVQEKRHFGTSWV 285
Query: 298 DRQFYFTQGGNLMSQARGDVAGG------LAMDIDNCSVMAVDCEDRRYCFQITSFDGKK 351
+ + ++ D G ++ + +C+ D ++R+CF + + D
Sbjct: 286 KHYCTYQRDSKQITMVPFDQKSGGKGGEDESVILKSCTRRKTDSIEKRFCFDVEAVDRPG 345
Query: 352 SSILQAESKKDHEEWI 367
+QA S++D W+
Sbjct: 346 VITMQALSEEDRRLWM 361
>gi|4505507 oligophrenin 1 [Homo sapiens]
Length = 802
Score = 80.1 bits (196), Expect = 7e-15
Identities = 82/407 (20%), Positives = 176/407 (43%), Gaps = 29/407 (7%)
Query: 3 GIDKLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHLTS 62
G L + DSP R L +E++ + ++ + + + + A S+A S
Sbjct: 2 GHPPLEFSDCYLDSPDFRERLKCYEQELERTNKFIKDVIKDGNALISAMRNYSSAVQKFS 61
Query: 63 KLLKEYEKQRFPLGGD----DEV-MSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQ 117
+ L+ ++ F GD DE+ ++ + ++F+++++E+ + ++ +D ++ P+
Sbjct: 62 QTLQSFQ---FDFIGDTLTDDEINIAESFKEFAELLNEVENERMMMVHNASDLLIKPLEN 118
Query: 118 FKERDLKEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQT 177
F++ + K+ F+ + ++R+ LS K++ +++ E V R ++
Sbjct: 119 FRKEQIGFTKERKKKFEKDGERFYSLLDRHLHLSSKKKESQLQ-EADLQVDKERHNFFES 177
Query: 178 MMHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVR 237
+ Y + +Q KK ++EP+L ++ + + E L + + + S+QN R
Sbjct: 178 SLDYVYQIQEVQESKKFNIVEPVLAFLHSLFISNSLTVE-LTQDFLPYKQQLQLSLQNTR 236
Query: 238 REMDSDIETMQQTIEDLEVASDPLYVPDPDPTKFPVNRNLTRKAGYLNARNKTGLVSSTW 297
S E M++ + ++ A P K P + GYL + K L S W
Sbjct: 237 NHFSSTREEMEELKKRMKEA--------PQTCKLPGQPTIE---GYLYTQEKWALGIS-W 284
Query: 298 DRQF--YFTQGGNL----MSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKK 351
+ + Y + L M Q G G L + + C + D+R+CF I + +
Sbjct: 285 VKYYCQYEKETKTLTMTPMEQKPGAKQGPLDLTLKYCVRRKTESIDKRFCFDIETNERPG 344
Query: 352 SSILQAESKKDHEEWICTINNISKQIYLSENPEETAARVNQSALEAV 398
+ LQA S+ + W+ ++ + IY S ++ +N+ + V
Sbjct: 345 TITLQALSEANRRLWMEAMDG-KEPIYHSPITKQQEMELNEVGFKFV 390
>gi|46094081 development and differentiation enhancing factor 1
[Homo sapiens]
Length = 1129
Score = 65.9 bits (159), Expect = 1e-10
Identities = 89/423 (21%), Positives = 190/423 (44%), Gaps = 47/423 (11%)
Query: 9 IEETLED--SPQT----------RSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSA 56
I ET ED SP T R+ + + EE + ++ +++ IY++ +
Sbjct: 31 IAETTEDYNSPTTSSFTTRLHNCRNTVTLLEEALDQDRTALQKVKKSVKAIYNSGQDHVQ 90
Query: 57 ATHLTSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPIT 116
+++L ++ L D+ + + +FS + ELS+ L L+ ++F +
Sbjct: 91 NEENYAQVLDKFGSNF--LSRDNPDLGTAFVKFSTLTKELSTLLKNLLQGLSHNVIFTLD 148
Query: 117 QFKERDLKEIL-TLKEVFQIASNDHDAAINRYSRLSKKRENDK----VKYEVT-----ED 166
+ DLK + LK+ F A D++ + + +KRE+ K ++ E+T E+
Sbjct: 149 SLLKGDLKGVKGDLKKPFDKAWKDYETKFTKIEK--EKREHAKQHGMIRTEITGAEIAEE 206
Query: 167 VYTSRKKQHQTMMHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFL 226
+ R+ M Y +N ++ KK + LL+ L+ Y AQ +FF+ G + ++L++++
Sbjct: 207 MEKERRLFQLQMCEYLIKVNEIKTKKGVDLLQNLIKYYHAQCNFFQDGLKTA-DKLKQYI 265
Query: 227 ANIGTSVQNVRREMDSDIETMQQTIEDLEVASDPLYVPDPDPTK--------FPVNRNL- 277
+ + N+++ D + + + + DL +S L + ++ N+
Sbjct: 266 EKLAADLYNIKQTQDEEKKQLT-ALRDLIKSSLQLDQKEDSQSRQGGYSMHQLQGNKEYG 324
Query: 278 TRKAGYLNARNKTGLVSSTWDRQFYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCED 337
+ K GYL K+ + W R+ + G L +++ C V + ED
Sbjct: 325 SEKKGYL--LKKSDGIRKVWQRRKCSVKNGILTISHATSNRQPAKLNLLTCQVKP-NAED 381
Query: 338 RRYCFQITSFDGKKSSILQAESKKDHEEWICTINNISKQ-IYLSENPEETAARVNQSALE 396
++ F + S + ++ QAE ++D+ WI + N ++ + ++ E++A +++LE
Sbjct: 382 KK-SFDLISHN--RTYHFQAEDEQDYVAWISVLTNSKEEALTMAFRGEQSA---GENSLE 435
Query: 397 AVT 399
+T
Sbjct: 436 DLT 438
>gi|206597522 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform b [Homo sapiens]
Length = 961
Score = 63.5 bits (153), Expect = 6e-10
Identities = 66/321 (20%), Positives = 137/321 (42%), Gaps = 34/321 (10%)
Query: 78 DDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEIL-TLKEVFQIA 136
DD + S +FS EL++ L + + + FP+ + DLK + LK+ F A
Sbjct: 90 DDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKA 149
Query: 137 SNDHDAAINRYSRLSKKRENDKVK---------YEVTEDVYTSRKKQHQTMMHYFCALNT 187
D++ I + + +K+E+ K+ E+ E++ R+ M Y +N
Sbjct: 150 WKDYETKITKIEK--EKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNE 207
Query: 188 LQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETM 247
++ KK + LL+ L+ Y AQ +FF+ G + + E L+ + + T + +++ D E
Sbjct: 208 IKIKKGVDLLQNLIKYFHAQCNFFQDGLKAV-ESLKPSIETLSTDLHTIKQAQD---EER 263
Query: 248 QQTIEDLEVASDPLYVPDPDPTKFPVN------------RNLTRKAGYLNARNKTGLVSS 295
+Q I+ ++ L V + ++ + + T + G L K+ +
Sbjct: 264 RQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSL--YKKSDGIRK 321
Query: 296 TWDRQFYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSIL 355
W ++ + G L +++ C V + + CF + S D ++
Sbjct: 322 VWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKT--NPEEKKCFDLISHD--RTYHF 377
Query: 356 QAESKKDHEEWICTINNISKQ 376
QAE +++ + W+ + N ++
Sbjct: 378 QAEDEQECQIWMSVLQNSKEE 398
>gi|4502249 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
isoform a [Homo sapiens]
Length = 1006
Score = 63.5 bits (153), Expect = 6e-10
Identities = 66/321 (20%), Positives = 137/321 (42%), Gaps = 34/321 (10%)
Query: 78 DDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEIL-TLKEVFQIA 136
DD + S +FS EL++ L + + + FP+ + DLK + LK+ F A
Sbjct: 90 DDPDLGSAFLKFSVFTKELTALFKNLIQNMNNIISFPLDSLLKGDLKGVKGDLKKPFDKA 149
Query: 137 SNDHDAAINRYSRLSKKRENDKVK---------YEVTEDVYTSRKKQHQTMMHYFCALNT 187
D++ I + + +K+E+ K+ E+ E++ R+ M Y +N
Sbjct: 150 WKDYETKITKIEK--EKKEHAKLHGMIRTEISGAEIAEEMEKERRFFQLQMCEYLLKVNE 207
Query: 188 LQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETM 247
++ KK + LL+ L+ Y AQ +FF+ G + + E L+ + + T + +++ D E
Sbjct: 208 IKIKKGVDLLQNLIKYFHAQCNFFQDGLKAV-ESLKPSIETLSTDLHTIKQAQD---EER 263
Query: 248 QQTIEDLEVASDPLYVPDPDPTKFPVN------------RNLTRKAGYLNARNKTGLVSS 295
+Q I+ ++ L V + ++ + + T + G L K+ +
Sbjct: 264 RQLIQLRDILKSALQVEQKEDSQIRQSTAYSLHQPQGNKEHGTERNGSL--YKKSDGIRK 321
Query: 296 TWDRQFYFTQGGNLMSQARGDVAGGLAMDIDNCSVMAVDCEDRRYCFQITSFDGKKSSIL 355
W ++ + G L +++ C V + + CF + S D ++
Sbjct: 322 VWQKRKCSVKNGFLTISHGTANRPPAKLNLLTCQVKT--NPEEKKCFDLISHD--RTYHF 377
Query: 356 QAESKKDHEEWICTINNISKQ 376
QAE +++ + W+ + N ++
Sbjct: 378 QAEDEQECQIWMSVLQNSKEE 398
>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
sapiens]
Length = 304
Score = 59.7 bits (143), Expect = 9e-09
Identities = 47/180 (26%), Positives = 96/180 (53%), Gaps = 14/180 (7%)
Query: 505 RFLGSMEVKSDDHPDVVYETMRQILAARAIHNIF--RMTESHLLVTCDCLKLIDPQTQVT 562
+FLGS EV+ +VV + +R++ AR I ++ + L ++ +K+++P+T+
Sbjct: 30 KFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEV 89
Query: 563 RLTFPLPCVVLYATHQENKRLFGFVLRTSSGRSESNLSSVCYIFESNNEGEKICDSVGLA 622
+ L + A + +KR+F F+ + SESN +CY+F+S E+I ++G A
Sbjct: 90 QHNCQLHRISFCADDKTDKRIFTFICKD----SESN-KHLCYVFDSEKCAEEITLTIGQA 144
Query: 623 KQIALHAELDR--RASEKQKEI----ERVKEKQQKELNKQKQIEKDLEEQSRLIAASSRP 676
+A L+ + E +K+I +R+++ + + + + +++ DLE Q R+ S+ P
Sbjct: 145 FDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQ-DLENQLRITQVSAPP 203
>gi|38569480 megakaryoblastic leukemia 2 protein [Homo sapiens]
Length = 1049
Score = 41.6 bits (96), Expect = 0.003
Identities = 33/106 (31%), Positives = 52/106 (49%), Gaps = 7/106 (6%)
Query: 608 SNNEGEKICDSVGLAKQIALHAELDRRASEKQKEIERVKEKQQKE------LNKQKQIEK 661
+NNE S L+ AE DR+ EK+K+IE +K K ++E L Q ++EK
Sbjct: 547 TNNEDSLSPTSSTLSNLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEK 606
Query: 662 DLEEQSRLIAASSRP-NQASSEGQFVVLSSSQSEESDLGEGGKKRE 706
++Q L A S P + S+ + L SS +E+ L + R+
Sbjct: 607 RGQQQRPLEAQPSAPGHSVKSDQKHGSLGSSIKDEASLPDCSSSRQ 652
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 39.3 bits (90), Expect = 0.013
Identities = 42/198 (21%), Positives = 88/198 (44%), Gaps = 23/198 (11%)
Query: 79 DEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASN 138
++ M++ ++F K DEL+ A +L + M +T KE++ ++ E +A
Sbjct: 849 EKEMATMKEEFQKTKDELAKSEAKRK-ELEEKM---VTLLKEKNDLQLQVQSEADSLADA 904
Query: 139 DHDAA------INRYSRLSKKRENDKVKYEVTEDVYTSRKKQHQTMMHYFCALNTLQYKK 192
+ I +++ + E + + E+ ++ ++K C+ + KK
Sbjct: 905 EERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDE-----CS----ELKK 955
Query: 193 KIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQTIE 252
I LE L ++ + K +EN + L E +A + ++ + +E + ET QQT++
Sbjct: 956 DIDDLELTLAKVEKE----KHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLD 1011
Query: 253 DLEVASDPLYVPDPDPTK 270
DL+ D + + TK
Sbjct: 1012 DLQAEEDKVNILTKAKTK 1029
>gi|4506509 regulator of G-protein signalling 12 isoform 2 [Homo
sapiens]
Length = 1376
Score = 38.5 bits (88), Expect = 0.022
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 18/123 (14%)
Query: 496 SILHQLFIVRFLGSMEVKS------DDHPDVVYETMRQILAARAIHNIFRMTESHLLVTC 549
SIL+ IV +LGS+E+ S D + MR++ A + IH++ M H
Sbjct: 224 SILNVAMIVGYLGSIELPSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMH----- 278
Query: 550 DCLKLIDPQTQVTRLTFPLPCVVLYATHQENKRLFGFV-LRTSSGRS-----ESNLSSVC 603
DC++L + V +P + A +++R FG V ++T+ S E L + C
Sbjct: 279 DCVQLSTDKAGVV-AEYPAEKLAFSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSC 337
Query: 604 YIF 606
++F
Sbjct: 338 HVF 340
>gi|38327601 regulator of G-protein signalling 12 isoform 1 [Homo
sapiens]
Length = 1447
Score = 38.5 bits (88), Expect = 0.022
Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 18/123 (14%)
Query: 496 SILHQLFIVRFLGSMEVKS------DDHPDVVYETMRQILAARAIHNIFRMTESHLLVTC 549
SIL+ IV +LGS+E+ S D + MR++ A + IH++ M H
Sbjct: 224 SILNVAMIVGYLGSIELPSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMH----- 278
Query: 550 DCLKLIDPQTQVTRLTFPLPCVVLYATHQENKRLFGFV-LRTSSGRS-----ESNLSSVC 603
DC++L + V +P + A +++R FG V ++T+ S E L + C
Sbjct: 279 DCVQLSTDKAGVV-AEYPAEKLAFSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSC 337
Query: 604 YIF 606
++F
Sbjct: 338 HVF 340
>gi|47717125 intersectin 1 isoform ITSN-s [Homo sapiens]
Length = 1220
Score = 37.7 bits (86), Expect = 0.037
Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 8/75 (10%)
Query: 621 LAKQIALHAELDR-RASEKQKEIERVKEKQQKELNKQKQIEKDLEEQSRLIAASSRPNQA 679
L KQ+ EL+R R E++KEIER +E ++EL +Q+Q+E + + L+ NQ
Sbjct: 409 LEKQLEKQRELERQREEERRKEIER-REAAKRELERQRQLEWERNRRQELL------NQR 461
Query: 680 SSEGQFVVLSSSQSE 694
+ E + +V+ ++ +
Sbjct: 462 NKEQEDIVVLKAKKK 476
Score = 32.3 bits (72), Expect = 1.6
Identities = 13/40 (32%), Positives = 28/40 (70%)
Query: 629 AELDRRASEKQKEIERVKEKQQKELNKQKQIEKDLEEQSR 668
AE +R+ E+Q++ + + + +K+L KQ+++E+ EE+ R
Sbjct: 389 AEQERKERERQEQERKRQLELEKQLEKQRELERQREEERR 428
Score = 30.4 bits (67), Expect = 5.9
Identities = 15/46 (32%), Positives = 27/46 (58%), Gaps = 6/46 (13%)
Query: 630 ELDRRASEKQKEIERV------KEKQQKELNKQKQIEKDLEEQSRL 669
E R+ E+ ++ER +E+Q++E +Q ++EK LE+Q L
Sbjct: 374 EQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQREL 419
>gi|47717123 intersectin 1 isoform ITSN-l [Homo sapiens]
Length = 1721
Score = 37.7 bits (86), Expect = 0.037
Identities = 24/75 (32%), Positives = 44/75 (58%), Gaps = 8/75 (10%)
Query: 621 LAKQIALHAELDR-RASEKQKEIERVKEKQQKELNKQKQIEKDLEEQSRLIAASSRPNQA 679
L KQ+ EL+R R E++KEIER +E ++EL +Q+Q+E + + L+ NQ
Sbjct: 409 LEKQLEKQRELERQREEERRKEIER-REAAKRELERQRQLEWERNRRQELL------NQR 461
Query: 680 SSEGQFVVLSSSQSE 694
+ E + +V+ ++ +
Sbjct: 462 NKEQEDIVVLKAKKK 476
Score = 32.3 bits (72), Expect = 1.6
Identities = 13/40 (32%), Positives = 28/40 (70%)
Query: 629 AELDRRASEKQKEIERVKEKQQKELNKQKQIEKDLEEQSR 668
AE +R+ E+Q++ + + + +K+L KQ+++E+ EE+ R
Sbjct: 389 AEQERKERERQEQERKRQLELEKQLEKQRELERQREEERR 428
Score = 30.4 bits (67), Expect = 5.9
Identities = 15/46 (32%), Positives = 27/46 (58%), Gaps = 6/46 (13%)
Query: 630 ELDRRASEKQKEIERV------KEKQQKELNKQKQIEKDLEEQSRL 669
E R+ E+ ++ER +E+Q++E +Q ++EK LE+Q L
Sbjct: 374 EQQRKEQERLAQLERAEQERKERERQEQERKRQLELEKQLEKQREL 419
>gi|124249396 coiled-coil domain containing 30 [Homo sapiens]
Length = 783
Score = 37.4 bits (85), Expect = 0.048
Identities = 51/195 (26%), Positives = 80/195 (41%), Gaps = 32/195 (16%)
Query: 534 IHNIFRMTES--HLLVTCDCLKLIDPQ--TQVTRLTFPLPCVVLYATHQENKRLFGFVLR 589
+HN+ +ES H L+ CD L+ + + T+V +L+ QE +L F L
Sbjct: 55 VHNLPGESESKDHFLIACDLLQRENSELETKVLKLS------------QEFAQLNHFTLG 102
Query: 590 TSSGRSESNLS-SVCYIFESNN------------EGEKICDSVGLAKQIALHAELDRRAS 636
+ S S + C ESN E E++C +G KQ + E + S
Sbjct: 103 GKTAPSNLITSENTCKDPESNEPILETEIQSRKEETEELCPKLGERKQKEIPEESVKEGS 162
Query: 637 ---EKQKEIERVKEKQQKELNKQKQIEKDLEEQSRLIAASSRPNQASSEGQFVVLSSSQS 693
E QKE + + K+ K++Q+ EE RL S NQ+ + Q SS S
Sbjct: 163 FPREGQKEEGSQQNRDMKDEEKEQQLTMKPEEIVRLREELSHINQSLLQSQSSGDSSDDS 222
Query: 694 EESDLGEGGKKRESE 708
G K + ++
Sbjct: 223 GAQHPSSGEKLKYNQ 237
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 37.4 bits (85), Expect = 0.048
Identities = 27/79 (34%), Positives = 44/79 (55%), Gaps = 7/79 (8%)
Query: 621 LAKQIALHAELDR-RASEKQKEIERVKEKQQKELNKQKQIEK--DLEEQSRLIAASSRPN 677
L K+ E+++ R EK+KE+ER KEK +KEL K K+ EK +LE++ + P
Sbjct: 545 LEKEQEKQREMEKERKQEKEKELERQKEK-EKELQKMKEQEKECELEKEREKLEEKIEPR 603
Query: 678 QASSEGQFVVLSSSQSEES 696
+ + E ++ +SE S
Sbjct: 604 EPNLE---PMVEKQESENS 619
Score = 33.5 bits (75), Expect = 0.70
Identities = 25/96 (26%), Positives = 48/96 (50%), Gaps = 5/96 (5%)
Query: 613 EKICDSVGLAKQIALHAELDRRASEKQKEIERVKEKQQKELNKQKQIEKDLEEQSRLIAA 672
+++ + +G+ ++ E+ R EK++E E+ EK+Q E ++K+ EKD E Q
Sbjct: 486 KRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQ-EQEREKEREKDRERQQEKEKE 544
Query: 673 SSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRESE 708
+ + E + Q +E +L E K++E E
Sbjct: 545 LEKEQEKQRE---MEKERKQEKEKEL-ERQKEKEKE 576
Score = 33.5 bits (75), Expect = 0.70
Identities = 20/48 (41%), Positives = 30/48 (62%), Gaps = 12/48 (25%)
Query: 630 ELDR-RASEKQKEIERVKEKQ-----------QKELNKQKQIEKDLEE 665
E DR R EK+KE+E+ +EKQ +KEL +QK+ EK+L++
Sbjct: 532 EKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQK 579
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 37.0 bits (84), Expect = 0.063
Identities = 43/186 (23%), Positives = 87/186 (46%), Gaps = 21/186 (11%)
Query: 79 DEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASN 138
++ M++ ++F K+ DEL+ A +L + M +T KE++ ++ E +A
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRK-ELEEKM---VTLLKEKNDLQLQVQAEAEGLADA 907
Query: 139 DH--DAAINRYSRLSKKRENDKVKYEVTEDV---YTSRKKQHQTMMHYFCALNTLQYKKK 193
+ D I +L K + + E E++ T++K++ + C+ + KK
Sbjct: 908 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE----CS----ELKKD 959
Query: 194 IALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQTIED 253
I LE L ++ + K +EN + L E +A + ++ + +E + E QQT++D
Sbjct: 960 IDDLELTLAKVEKE----KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1015
Query: 254 LEVASD 259
L+ D
Sbjct: 1016 LQAEED 1021
Score = 36.6 bits (83), Expect = 0.082
Identities = 52/262 (19%), Positives = 108/262 (41%), Gaps = 38/262 (14%)
Query: 26 FEEDATAISNYMNQLYQAMHRIYDAQNELSAA---THLTSKLLKEYEKQRFPLGGDDEVM 82
+EE + + I D +++ H K+ K+ E+++ L E
Sbjct: 1494 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA 1553
Query: 83 SSTLQ----QFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASN 138
++L+ + ++ EL+ + + ++A+ I Q K ++ + +++
Sbjct: 1554 EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE-EIDQLKRNHIRIVESMQSTLDAEIR 1612
Query: 139 DHDAAINRYSRLSKKRENDKVKYEV---------TEDVYTSRKKQ---HQTMMHYFCALN 186
+ AI RL KK E D + E+ E + R Q T +H AL
Sbjct: 1613 SRNDAI----RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALR 1668
Query: 187 TLQ-YKKKIALLEPLLGYMQAQISFF-----------KMGSENLNEQLE--EFLANIGTS 232
+ + K+++A++E +QA+I K+ + L + E + L TS
Sbjct: 1669 SQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTS 1728
Query: 233 VQNVRREMDSDIETMQQTIEDL 254
+ N ++++++DI MQ +ED+
Sbjct: 1729 LINTKKKLETDISQMQGEMEDI 1750
Score = 33.1 bits (74), Expect = 0.91
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Query: 606 FESNNEGEKICDSVGLAKQIALHA-ELDRRASEKQKEIERVKEKQQKELNKQKQIEKDLE 664
FE +N KI D L Q+ EL R E ++EIE + + K ++ + ++LE
Sbjct: 1091 FEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 665 EQSRLIAASSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRESEA 709
E S + + A E + Q DL E + E+ A
Sbjct: 1151 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1195
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 37.0 bits (84), Expect = 0.063
Identities = 43/186 (23%), Positives = 87/186 (46%), Gaps = 21/186 (11%)
Query: 79 DEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASN 138
++ M++ ++F K+ DEL+ A +L + M +T KE++ ++ E +A
Sbjct: 852 EKEMATMKEEFQKIKDELAKSEAKRK-ELEEKM---VTLLKEKNDLQLQVQAEAEGLADA 907
Query: 139 DH--DAAINRYSRLSKKRENDKVKYEVTEDV---YTSRKKQHQTMMHYFCALNTLQYKKK 193
+ D I +L K + + E E++ T++K++ + C+ + KK
Sbjct: 908 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE----CS----ELKKD 959
Query: 194 IALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQTIED 253
I LE L ++ + K +EN + L E +A + ++ + +E + E QQT++D
Sbjct: 960 IDDLELTLAKVEKE----KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1015
Query: 254 LEVASD 259
L+ D
Sbjct: 1016 LQAEED 1021
Score = 36.6 bits (83), Expect = 0.082
Identities = 52/262 (19%), Positives = 108/262 (41%), Gaps = 38/262 (14%)
Query: 26 FEEDATAISNYMNQLYQAMHRIYDAQNELSAA---THLTSKLLKEYEKQRFPLGGDDEVM 82
+EE + + I D +++ H K+ K+ E+++ L E
Sbjct: 1494 YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEA 1553
Query: 83 SSTLQ----QFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASN 138
++L+ + ++ EL+ + + ++A+ I Q K ++ + +++
Sbjct: 1554 EASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE-EIDQLKRNHIRIVESMQSTLDAEIR 1612
Query: 139 DHDAAINRYSRLSKKRENDKVKYEV---------TEDVYTSRKKQ---HQTMMHYFCALN 186
+ AI RL KK E D + E+ E + R Q T +H AL
Sbjct: 1613 SRNDAI----RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALR 1668
Query: 187 TLQ-YKKKIALLEPLLGYMQAQISFF-----------KMGSENLNEQLE--EFLANIGTS 232
+ + K+++A++E +QA+I K+ + L + E + L TS
Sbjct: 1669 SQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTS 1728
Query: 233 VQNVRREMDSDIETMQQTIEDL 254
+ N ++++++DI MQ +ED+
Sbjct: 1729 LINTKKKLETDISQMQGEMEDI 1750
Score = 33.1 bits (74), Expect = 0.91
Identities = 28/105 (26%), Positives = 44/105 (41%), Gaps = 1/105 (0%)
Query: 606 FESNNEGEKICDSVGLAKQIALHA-ELDRRASEKQKEIERVKEKQQKELNKQKQIEKDLE 664
FE +N KI D L Q+ EL R E ++EIE + + K ++ + ++LE
Sbjct: 1091 FEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1150
Query: 665 EQSRLIAASSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRESEA 709
E S + + A E + Q DL E + E+ A
Sbjct: 1151 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1195
>gi|122937227 U2-associated SR140 protein [Homo sapiens]
Length = 1029
Score = 37.0 bits (84), Expect = 0.063
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 11/83 (13%)
Query: 637 EKQKEIERVKEKQQKELNKQKQIEKD----------LEEQSRLIAASSRPNQASSEGQFV 686
EK+KE+ER +E+ +K+ K + KD +E+ R + S P+++SS G+ V
Sbjct: 886 EKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSS-GRRV 944
Query: 687 VLSSSQSEESDLGEGGKKRESEA 709
S +SE S+ E K S +
Sbjct: 945 KSPSPKSERSERSERSHKESSRS 967
>gi|66792814 retrotransposon gag domain containing 4 [Homo sapiens]
Length = 569
Score = 37.0 bits (84), Expect = 0.063
Identities = 24/84 (28%), Positives = 46/84 (54%), Gaps = 15/84 (17%)
Query: 626 ALHAELDRRASEKQKEIERVKEKQQKELNKQKQI-EKDLEEQSRLIAASSRPNQASSEGQ 684
A E+ + E+ K+ E +K+K++KE +++++ +K+ EE+ R N+ EG+
Sbjct: 368 AFQQEMKEKEEEEMKKEEEMKKKEEKEEEEEEEMKQKEEEEEIR--------NKNEEEGE 419
Query: 685 FVVLSSSQSEESDLGEGGKKRESE 708
S+ EE + +GG+K E E
Sbjct: 420 ------SKDEEDEDEDGGQKPEGE 437
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 36.6 bits (83), Expect = 0.082
Identities = 64/315 (20%), Positives = 127/315 (40%), Gaps = 32/315 (10%)
Query: 6 KLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAATHL----- 60
K ++E + + + S FEE + N+L + + + +++LS+ T L
Sbjct: 908 KAHVQEVAQHNLKEASSASQFEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQ 967
Query: 61 -TSKLLK----EYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPI 115
+KL K + ++Q + L+ S+ E+S L + L DA+
Sbjct: 968 DENKLFKSQIEQLKQQNYQQASSFPPHEELLKVISEREKEISGLWNELDS-LKDAVEHQR 1026
Query: 116 TQFKER-------DLKEILTLKEVFQIASNDHDAAINRYSR-LSKKRENDKVKYEVTEDV 167
+ ER +L+ LK++F S + + + KK + +E+V
Sbjct: 1027 KKNNERQQQVEAVELEAKEVLKKLFPKVSVPSNLSYGEWLHGFEKKAKECMAGTSGSEEV 1086
Query: 168 -YTSRKKQHQTMMHYFCALNTLQYKKKIALLEPLLGYMQAQI----SFFKMGSENLNEQL 222
K + MH L +YK +A E +L +Q + + +K+ + ++ +
Sbjct: 1087 KVLEHKLKEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTI 1146
Query: 223 EEFLANIGTSVQNVR--REMDSDIETMQQTIEDLEVASD------PLYVPDPDPTKFPVN 274
++ ++ +S Q + R + DIE +++ E LE+ + YV + K +N
Sbjct: 1147 KQMQSSFTSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKAQLN 1206
Query: 275 RNLTRKAGYLNARNK 289
LT+ N R K
Sbjct: 1207 ETLTKLRTEQNERQK 1221
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 36.6 bits (83), Expect = 0.082
Identities = 60/266 (22%), Positives = 110/266 (41%), Gaps = 34/266 (12%)
Query: 6 KLPIEETLEDSPQTRSLLGVFEEDATAISNYMNQLYQAMHRI------YDAQNELSAATH 59
KL + LED L EE+ A + + L A H Y+ + E A
Sbjct: 1305 KLTYTQQLED------LKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQ 1358
Query: 60 -LTSKLLKEYEKQRFPLGGDDEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQF 118
+ SK E + R D + L++ K + + A + + +A + +
Sbjct: 1359 RVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQ-EAEEAVEAVNAKCSSLEKT 1417
Query: 119 KERDLKEILTLKEVFQIASNDHDAAINRYSR-LSKKRENDKVKYEVTEDVYTSRKKQHQT 177
K R EI L + SN AA+++ R K K KYE ++ S +K+ ++
Sbjct: 1418 KHRLQNEIEDLMVDVE-RSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1476
Query: 178 MMHYFCALNTLQYKKKIALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTS----- 232
L+T +K K A E L + FK ++NL E++ + +G+S
Sbjct: 1477 -------LSTELFKLKNAYEESL-----EHLETFKRENKNLQEEISDLTEQLGSSGKTIH 1524
Query: 233 -VQNVRREMDSDIETMQQTIEDLEVA 257
++ VR++++++ +Q +E+ E +
Sbjct: 1525 ELEKVRKQLEAEKMELQSALEEAEAS 1550
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 36.6 bits (83), Expect = 0.082
Identities = 57/277 (20%), Positives = 115/277 (41%), Gaps = 45/277 (16%)
Query: 18 QTRSLLGVFEEDATAISNYMNQLYQAMHRIYDAQNELSAAT----------HLTSKLLKE 67
++RSL + A ++QL + Q E+S T H K+ K+
Sbjct: 1477 ESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQ 1536
Query: 68 YEKQRFPLGGDDEVMSSTLQ----QFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDL 123
E+++ L E ++L+ + ++ EL+ + + ++A+ I Q K +
Sbjct: 1537 VEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDE-EIDQMKRNHI 1595
Query: 124 KEILTLKEVFQIASNDHDAAINRYSRLSKKRENDKVKYEV---------TEDVYTSRKKQ 174
+ + +++ + AI RL KK E D + E+ E + R Q
Sbjct: 1596 RIVESMQSTLDAEIRSRNDAI----RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQ 1651
Query: 175 ---HQTMMHYFCALNTLQ-YKKKIALLEPLLGYMQAQISFF-----------KMGSENLN 219
T +H AL + + K+++A++E +QA+I K+ + L
Sbjct: 1652 AILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELL 1711
Query: 220 EQLE--EFLANIGTSVQNVRREMDSDIETMQQTIEDL 254
+ E + L TS+ N ++++++DI +Q +ED+
Sbjct: 1712 DASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDI 1748
Score = 33.5 bits (75), Expect = 0.70
Identities = 41/186 (22%), Positives = 86/186 (46%), Gaps = 21/186 (11%)
Query: 79 DEVMSSTLQQFSKVIDELSSCHAVLSTQLADAMMFPITQFKERDLKEILTLKEVFQIASN 138
++ M++ ++F K +EL+ A +L + M +T +E++ ++ E +A
Sbjct: 850 EKEMANMKEEFEKTKEELAKTEAKRK-ELEEKM---VTLMQEKNDLQLQVQAEADSLADA 905
Query: 139 DH--DAAINRYSRLSKKRENDKVKYEVTEDV---YTSRKKQHQTMMHYFCALNTLQYKKK 193
+ D I +L K + + E E++ T++K++ + C+ + KK
Sbjct: 906 EERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDE----CS----ELKKD 957
Query: 194 IALLEPLLGYMQAQISFFKMGSENLNEQLEEFLANIGTSVQNVRREMDSDIETMQQTIED 253
I LE L ++ + K +EN + L E +A + ++ + +E + E QQT++D
Sbjct: 958 IDDLELTLAKVEKE----KHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDD 1013
Query: 254 LEVASD 259
L+ D
Sbjct: 1014 LQAEED 1019
Score = 32.0 bits (71), Expect = 2.0
Identities = 27/105 (25%), Positives = 43/105 (40%), Gaps = 1/105 (0%)
Query: 606 FESNNEGEKICDSVGLAKQIALHA-ELDRRASEKQKEIERVKEKQQKELNKQKQIEKDLE 664
FE + KI D L Q+ EL R E ++EIE + + K ++ + ++LE
Sbjct: 1089 FEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELE 1148
Query: 665 EQSRLIAASSRPNQASSEGQFVVLSSSQSEESDLGEGGKKRESEA 709
E S + + A E + Q DL E + E+ A
Sbjct: 1149 EISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATA 1193
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 36.2 bits (82), Expect = 0.11
Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 7/88 (7%)
Query: 587 VLRTSSGRSESNLS-SVCYIFESNNEGEKICDSVGLAKQIALHAELDRRASEKQKEIERV 645
+LR S SE+++ V + E + S G K +A EL R+ E Q++++
Sbjct: 321 ILREGSSESETSVRRKVSLVLEKMQP--LVMVSSGSTKAVAGQGELTRKVEELQRKLDEE 378
Query: 646 KEKQQK----ELNKQKQIEKDLEEQSRL 669
+K+QK ++ ++Q+E+ EE SRL
Sbjct: 379 VKKRQKLEPSQVGLERQLEEKTEECSRL 406
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.358
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,853,463
Number of Sequences: 37866
Number of extensions: 1074530
Number of successful extensions: 7765
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 207
Number of HSP's that attempted gapping in prelim test: 6750
Number of HSP's gapped (non-prelim): 1187
length of query: 709
length of database: 18,247,518
effective HSP length: 109
effective length of query: 600
effective length of database: 14,120,124
effective search space: 8472074400
effective search space used: 8472074400
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.