BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|68563515 keratinocyte proline-rich protein [Homo sapiens] (579 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|68563515 keratinocyte proline-rich protein [Homo sapiens] 1276 0.0 gi|62000702 diacylglycerol kinase kappa [Homo sapiens] 83 8e-16 gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 81 2e-15 gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens] 75 2e-13 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 75 2e-13 gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 71 2e-12 gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom... 71 2e-12 gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ... 71 2e-12 gi|67003568 skin-specific protein 32 [Homo sapiens] 69 1e-11 gi|153792074 proline rich 12 [Homo sapiens] 67 6e-11 gi|169211819 PREDICTED: keratin associated protein [Homo sapiens] 66 8e-11 gi|239745811 PREDICTED: hypothetical protein XP_002343557 [Homo ... 66 8e-11 gi|83977459 pleckstrin homology-like domain, family A, member 1 ... 64 3e-10 gi|169212026 PREDICTED: keratin associated protein [Homo sapiens] 62 1e-09 gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 62 1e-09 gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 62 1e-09 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 62 1e-09 gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 62 2e-09 gi|154800453 tastin isoform 1 [Homo sapiens] 61 3e-09 gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] 60 7e-09 gi|239744133 PREDICTED: hypothetical protein [Homo sapiens] 59 2e-08 gi|33186895 selenoprotein V [Homo sapiens] 59 2e-08 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 58 2e-08 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 58 2e-08 gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 58 3e-08 gi|47132519 Ras association and pleckstrin homology domains 1 is... 57 5e-08 gi|239755326 PREDICTED: hypothetical protein [Homo sapiens] 57 6e-08 gi|71274152 hypothetical protein LOC388939 [Homo sapiens] 57 6e-08 gi|117938768 GNAS complex locus alex [Homo sapiens] 56 8e-08 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 56 8e-08 >gi|68563515 keratinocyte proline-rich protein [Homo sapiens] Length = 579 Score = 1276 bits (3303), Expect = 0.0 Identities = 579/579 (100%), Positives = 579/579 (100%) Query: 1 MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS 60 MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS Sbjct: 1 MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS 60 Query: 61 DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV 120 DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV Sbjct: 61 DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV 120 Query: 121 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST 180 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST Sbjct: 121 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST 180 Query: 181 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY 240 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY Sbjct: 181 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY 240 Query: 241 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR 300 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR Sbjct: 241 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR 300 Query: 301 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ 360 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ Sbjct: 301 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ 360 Query: 361 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP 420 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP Sbjct: 361 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP 420 Query: 421 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP 480 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP Sbjct: 421 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP 480 Query: 481 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE 540 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE Sbjct: 481 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE 540 Query: 541 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF 579 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF Sbjct: 541 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF 579 >gi|62000702 diacylglycerol kinase kappa [Homo sapiens] Length = 1271 Score = 82.8 bits (203), Expect = 8e-16 Identities = 61/184 (33%), Positives = 68/184 (36%), Gaps = 7/184 (3%) Query: 331 SPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQ 390 SP P PP P PP P+P CPEL P P + Sbjct: 23 SPEPPPPWPPPPPPPAPPPAPPLLSEASPEPI-PEPCPELAPGPCPEATSESATELYTEP 81 Query: 391 CPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLP 450 PE + PAP P P P + EP P P P +E P P PAL P P P Sbjct: 82 TPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPEL 141 Query: 451 RPGQCEIPEPRPCLQPCEH--PEPCPR--PEPIPLPAPC--PSPEPCRETWRSPSPCWGP 504 P P P +P PE CP PE P PAPC P RE SP P Sbjct: 142 TPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSP 201 Query: 505 NPVP 508 +P P Sbjct: 202 SPSP 205 Score = 76.3 bits (186), Expect = 7e-14 Identities = 62/192 (32%), Positives = 69/192 (35%), Gaps = 22/192 (11%) Query: 358 GPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPC---- 413 G QP+ P P P P P PP + PE P P P P L P PC Sbjct: 17 GEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPE------PIPEPCPELAPGPCPEAT 70 Query: 414 ------ISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRP----GQCEIPEPRPC 463 + EP P P SEP P PA P P P P P P P P Sbjct: 71 SESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPA 130 Query: 464 LQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGP--NPVPYPGDLGCHESSPH 521 L+ P P PE P AP P+PEP E P P P P P L C + Sbjct: 131 LESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRE 190 Query: 522 RLDTEAPYCGPS 533 R +P PS Sbjct: 191 RGLKTSPSPSPS 202 Score = 72.8 bits (177), Expect = 8e-13 Identities = 60/185 (32%), Positives = 71/185 (38%), Gaps = 33/185 (17%) Query: 371 RPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAP------RPRLRPEPCISLEPRPRPLP 424 +P P P P + PP P PPPAP P PEPC L P P P Sbjct: 19 QPAESPEPPPPWPPP---------PPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEA 69 Query: 425 RQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLP-- 482 S LY EP TP P P P P P +P P P PEP P P Sbjct: 70 TSESATELYTEP------TPEPATEP----ASEPAPEPATEPAPEPATEPAPEPAPEPAT 119 Query: 483 --APCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE 540 AP P+PEP E+ P+P P P E +P + AP P + + + Sbjct: 120 ESAPEPTPEPALESVPEPAPELTPEVAPELAP----EPTPEPVTELAPEFCPEAAPEFRP 175 Query: 541 SGAGC 545 S A C Sbjct: 176 SPAPC 180 Score = 72.4 bits (176), Expect = 1e-12 Identities = 55/169 (32%), Positives = 63/169 (37%), Gaps = 26/169 (15%) Query: 384 PPRRLDQCPESPLQRCPPPAPRPRLRPEPC------ISLEPRPRPLPRQLSEPC------ 431 PP+ +Q ESP P P P P P P S EP P P P PC Sbjct: 13 PPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSE 72 Query: 432 ----LYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487 LY EP P P P P P P P P +P P P P E P P P P+ Sbjct: 73 SATELYTEPTP--EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPA 130 Query: 488 ----PEPCRETWRSPSPCWGPNPVPYP----GDLGCHESSPHRLDTEAP 528 PEP E +P P P P P C E++P + AP Sbjct: 131 LESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAP 179 >gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] Length = 411 Score = 81.3 bits (199), Expect = 2e-15 Identities = 65/211 (30%), Positives = 81/211 (38%), Gaps = 19/211 (9%) Query: 341 QRCPVEIPPIRRRSQSCGPQ-PSWGASCPELRPH-VEPRPLPSFCPPRRLDQCPESPLQR 398 Q+ P +P R R P P+ AS P+ P + P P+ C + P Q+ Sbjct: 27 QQQPQRVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQK 86 Query: 399 CPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIP 458 P A L P P P+P + P P PLP P P P P P P Sbjct: 87 GIPAA------------LSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAP 134 Query: 459 EPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWR--SPSPCWGPNPVPYPGDLGCH 516 P P P + P P P P P+ P P P P + +P P GPNP P PG + Sbjct: 135 IPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGP 194 Query: 517 ESSPHRLDTEAPYCGPSSYNQGQESGAGCGP 547 P + P GP S G SG GP Sbjct: 195 IPGPISVPIPGPIPGPIS---GPISGPNPGP 222 Score = 63.9 bits (154), Expect = 4e-10 Identities = 74/250 (29%), Positives = 89/250 (35%), Gaps = 32/250 (12%) Query: 322 GPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPS 381 GP CR + P + P P+ P I +Q GP P P P P P+P+ Sbjct: 79 GPGCRAQKGIPAA---LSPGPGPIPAP-IPGPAQIPGPLPG-SIPGPIPGPAQIPSPIPA 133 Query: 382 FCP-----PRRLDQCPESPLQR-------CPPPAPRPRLRPEPCISLEPRPRPLPRQLSE 429 P P ++ P+ P P P P P P P P+P +S Sbjct: 134 PIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISG 193 Query: 430 PCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPE 489 P P +P P P P+ P G P P P P P P P P PI P P P Sbjct: 194 PIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPG 253 Query: 490 PCRETWRSPSPCWGPNP----VPYPGDL--------GCHESSPHRLDTEAPYCGPSSYNQ 537 P P P GP P +P PG L SP L AP GP S Sbjct: 254 PIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGS--- 310 Query: 538 GQESGAGCGP 547 G SG+ P Sbjct: 311 GPGSGSVPAP 320 Score = 53.5 bits (127), Expect = 5e-07 Identities = 66/227 (29%), Positives = 79/227 (34%), Gaps = 60/227 (26%) Query: 328 EISSPCCPRQVP-PQRCPVEIP-PIRRRSQS--CGPQPSWGA-SCPELRPHVEPRPLPSF 382 +I SP P +P P PV+IP P R GP P G S P P+ P P P+ Sbjct: 126 QIPSPI-PAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPN- 183 Query: 383 CPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRP 442 P P P P P P P P P+P +S P P P P P Sbjct: 184 -----------------PGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGP 226 Query: 443 TPRPVPLPRPGQCEIP--EPRPCLQPCEHPEPCPRPEPI--PLPAPCPSPEPCR------ 492 P P+ P PG P P P L P P P P PI P+P+P P P R Sbjct: 227 IPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGP 286 Query: 493 --------------------------ETWRSPSPCWGPNPVPYPGDL 513 + P+P GP +P P L Sbjct: 287 ILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPL 333 Score = 49.7 bits (117), Expect = 7e-06 Identities = 37/127 (29%), Positives = 46/127 (36%), Gaps = 26/127 (20%) Query: 400 PPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPA--------LRPTPRPVPLPR 451 P P P P P P P P P P P L P P+P + P P P +P Sbjct: 218 PNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPG 277 Query: 452 PGQCEIPEP------------RPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPS 499 PG+ + P P P L P P P +P P P P P +P+ Sbjct: 278 PGRLQGPGPILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLP------APA 331 Query: 500 PCWGPNP 506 P W +P Sbjct: 332 PLWPQSP 338 >gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens] Length = 299 Score = 74.7 bits (182), Expect = 2e-13 Identities = 58/186 (31%), Positives = 62/186 (33%), Gaps = 14/186 (7%) Query: 332 PCCPRQVPPQRCPVEIPPI-----RRRSQSCGPQPSWG--ASCPELRPHVEPRPLPSFCP 384 P +P CP P + R Q C P P AS P R P P C Sbjct: 15 PLSMAAIPTYPCPAVSPALLLPRPERVKQCCQPCPRRDLLASWP-CRLFSSETPRPRDCE 73 Query: 385 PRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTP 444 R C + C P PR P P PRPR C P P P P Sbjct: 74 TPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRP 133 Query: 445 RPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEP----IPLPAPCPSPEPCRETWRSPSP 500 R PRP CE P PR C P P C P P P P C +P P P Sbjct: 134 RDCETPRPRDCETPRPRDCDTP--RPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRD 191 Query: 501 CWGPNP 506 C P P Sbjct: 192 CDTPRP 197 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 74.7 bits (182), Expect = 2e-13 Identities = 87/300 (29%), Positives = 100/300 (33%), Gaps = 63/300 (21%) Query: 253 SRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR 312 SR PPP L P P P +S P P E P +PP P S P Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSP--PPEDSPT--SPPPEDSPA--SPPPED 713 Query: 313 PISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELR- 371 + S P + CPR P P R P+P P+ Sbjct: 714 SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP------RPEEPHLSPRPEEPHLSPQAEE 767 Query: 372 PHVEPRPL-PSFCP----PRRLDQCPESPLQRCP------PPAPRPRLRP---EPCISLE 417 PH+ P+P P C P Q L P P P L P EPC+S + Sbjct: 768 PHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQ 827 Query: 418 PRPRPLPRQLSEPCLYPEP----------LPALRPTPRPVPLPRPGQCEIPEPRPCLQPC 467 P L Q EPCL P P P L P P P PGQC PE P P Sbjct: 828 PEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPP-EEPGQCPAPEELPLFPPP 886 Query: 468 EHP-------EPC----------PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYP 510 P EP P PE +PL PS EP P P+P+P P Sbjct: 887 GEPSLSPLLGEPALSEPGEPPLSPLPEELPL---SPSGEPSLSPQLMP-----PDPLPPP 938 Score = 53.5 bits (127), Expect = 5e-07 Identities = 85/292 (29%), Positives = 105/292 (35%), Gaps = 45/292 (15%) Query: 255 CLPPP-RRLQLFPRSCSPPRRFEPCSSSYLPLRP-SEGFPNYCTPPRRSEPIYNSRCPRR 312 CL PP L C R C + L P SE F NY S C R Sbjct: 302 CLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENY------------SLCHR- 348 Query: 313 PISSCSQRRGPKCRIEIS---SPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPE 369 C + +G + ++ +P C R PP+ +C QP G Sbjct: 349 ----CHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPK-GGHVTS 403 Query: 370 LRPHVEPRPLPSFCPPR-----RLDQCPESPLQR----CPPPAPRPRLRPEPCISLEPRP 420 ++P EP PL P +L+ E+PL PPP P L P P S P Sbjct: 404 MQPK-EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESP-LSPPPEES-PTSP 460 Query: 421 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHP---EPCPRPE 477 P +LS P PE LPA P P + L RP + P P P P P E Sbjct: 461 PPEASRLSPP---PEELPA-SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLE 516 Query: 478 PIPLPAPCPSP-EPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAP 528 PL P SP P ET SP P +P+ P + P L T P Sbjct: 517 ESPLSPPEESPPSPALETPLSPPP--EASPLSPPFEESPLSPPPEELPTSPP 566 Score = 52.8 bits (125), Expect = 9e-07 Identities = 82/295 (27%), Positives = 92/295 (31%), Gaps = 53/295 (17%) Query: 253 SRCLPPPRRLQLFP-------------RSCSPPRRFEPCSS--SYLPLRPSEGFPNYCTP 297 SR PPP L P SPP P S P P E P +P Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP--LSP 522 Query: 298 PRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSC 357 P S P P P S P SP P PP+ P PP R S Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPF----EESPLSP---PPEELPTSPPPEASRL-SP 574 Query: 358 GPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRP---RLRPEPCI 414 P+ S + PE P P PP ++ P SP P +P P RL P P Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPP--FEESPLSPPPEESPLSPPPEASRLSPPPED 632 Query: 415 S-LEPRPRPLPRQLSEPCLYPEPLPA---LRPTPRPVPLPRPGQCEIPEPRP----CLQP 466 S + P P P PLP L P P PL P + P P P Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692 Query: 467 CEHPEPCPRPEPIPLPAP---------------CPSPEPCRETWRSPSPCWGPNP 506 E P PE P P P PE + RS P P P Sbjct: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747 Score = 44.3 bits (103), Expect = 3e-04 Identities = 73/264 (27%), Positives = 86/264 (32%), Gaps = 75/264 (28%) Query: 256 LPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPIS 315 LPPP L P P P +S P P E P + P+ + RP+ Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSP--PPEELP--------ASPLPEALHLSRPLE 490 Query: 316 SCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVE 375 SP P PP+ P+ PP S P S PE P Sbjct: 491 E--------------SPLSP---PPEESPLSPPP---ESSPFSPLEESPLSPPEESP--- 527 Query: 376 PRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP-------RQLS 428 P P+ E+PL PPP P P L P P LP +LS Sbjct: 528 --PSPAL----------ETPLS--PPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLS 573 Query: 429 EPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAP---- 484 P PE P + P P P+ P PE P E P PE PL P Sbjct: 574 PP---PEESP-MSPPPEESPMSPP-----PEASRLFPPFEESPLSPPPEESPLSPPPEAS 624 Query: 485 --CPSPE------PCRETWRSPSP 500 P PE P E+ SP P Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPP 648 Score = 41.2 bits (95), Expect = 0.003 Identities = 85/324 (26%), Positives = 108/324 (33%), Gaps = 74/324 (22%) Query: 257 PPPRRLQLFPRSCSP---PRRFEPCSSSYLP---LRPSEGFPNYCTPPRRSEPIYNSRCP 310 P P L L P++ P P EPC S L P P C PR E + Sbjct: 799 PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP--CLSPRPEESHLSPELE 856 Query: 311 RRPISSCSQRRGPKCRIEISSPCCPRQVP-PQRCPVEIPPIRRRSQSCGPQPSWG----- 364 + P+S ++ P P Q P P+ P+ PP +P+ Sbjct: 857 KPPLSPRPEK----------PPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP 906 Query: 365 --ASCPE---LRPHVEPRPLPSFCPPRRLDQCPESPL-QRCPPPAPRPRLR--------- 409 + PE L P EP P PP L P SP+ PPA P Sbjct: 907 PLSPLPEELPLSPSGEPSLSPQLMPPDPLPP-PLSPIITAAAPPALSPLGELEYPFGAKG 965 Query: 410 ---PEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRP----------VPLPRPGQCE 456 PE ++ P+ C PEP+P + P P + P P QC Sbjct: 966 DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS 1025 Query: 457 IPEPRPCLQPCEHPEPCPRPEPIPLPAPCP-SP--------------EPCRETWRSPS-P 500 P + L P P P +PL P P SP E E P P Sbjct: 1026 -PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECP 1084 Query: 501 CWGP---NPVPYP-GDLGCHESSP 520 P +P+P P GDL C SP Sbjct: 1085 ALEPSATSPLPSPMGDLSCPAPSP 1108 Score = 41.2 bits (95), Expect = 0.003 Identities = 37/125 (29%), Positives = 47/125 (37%), Gaps = 16/125 (12%) Query: 401 PPAPRPRLRPE---PCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEI 457 P +P LRP+ P +L P P P + P Y +P TPRP P P C + Sbjct: 2340 PQSPGLGLRPQEPPPAQALAPSPPSHP-DIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398 Query: 458 PEPRPCLQPCEHPEPCPR----------PEPIPLPAPCPSPEPCRETWRSPSPCWGPNPV 507 P P P+ P P+ A CPSP R ++SP P P Sbjct: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPR--FQSPDPYSRPPSR 2456 Query: 508 PYPGD 512 P D Sbjct: 2457 PQSRD 2461 Score = 36.2 bits (82), Expect = 0.085 Identities = 44/152 (28%), Positives = 54/152 (35%), Gaps = 34/152 (22%) Query: 335 PRQVPPQRCPVEIPP----IRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFC--PPRRL 388 P++ PP + PP I R P P L P +P P S C PPR L Sbjct: 2349 PQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ-----PPLTPRPQPPPPESCCALPPRSL 2403 Query: 389 DQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPV- 447 P P R P P+ + L PRP LS P P+ +P P Sbjct: 2404 ---PSDPFSRVPAS---PQSQSSSQSPLTPRP------LSAEAFCPSPVTPRFQSPDPYS 2451 Query: 448 -PLPRPGQCEIPEPRPCLQPCEHPEPCPRPEP 478 P R P+ R P P PRP+P Sbjct: 2452 RPPSR------PQSRDPFAPLHKP---PRPQP 2474 Score = 33.5 bits (75), Expect = 0.55 Identities = 28/85 (32%), Positives = 32/85 (37%), Gaps = 18/85 (21%) Query: 392 PESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPR 451 PE P PPP+P L P P P PL +EP P P P PLP Sbjct: 4911 PEEP---SPPPSP---LAPSPA---SPPTEPLVELPTEPLAEP---------PVPSPLPL 4952 Query: 452 PGQCEIPEPRPCLQPCEHPEPCPRP 476 E P+P +P E E P Sbjct: 4953 ASSPESARPKPRARPPEEGEDSRPP 4977 Score = 32.0 bits (71), Expect = 1.6 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 15/86 (17%) Query: 425 RQLSEPCLYPEPLPALRPTPRPVPL-PRPGQCEIPEPRPCLQ-PCEHPEPCPRPEPIPLP 482 RQLS P P P+P P PL P P P P ++ P E P P P+PL Sbjct: 4904 RQLSAP-------PPEEPSPPPSPLAPSPAS---PPTEPLVELPTEPLAEPPVPSPLPLA 4953 Query: 483 APCPSPEPCRETWRSPSPCWGPNPVP 508 + SPE R R+ P G + P Sbjct: 4954 S---SPESARPKPRARPPEEGEDSRP 4976 Score = 30.8 bits (68), Expect = 3.6 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 5/65 (7%) Query: 368 PELRPHVEPRPL---PSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424 P P P PL P+ P L + P PL P P+P P L P S P+PR P Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLP-LASSP-ESARPKPRARP 4967 Query: 425 RQLSE 429 + E Sbjct: 4968 PEEGE 4972 Score = 30.4 bits (67), Expect = 4.7 Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 2/59 (3%) Query: 422 PLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCE--IPEPRPCLQPCEHPEPCPRPEP 478 P P + S P P PA PT V LP E +P P P E P PR P Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967 >gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 71.2 bits (173), Expect = 2e-12 Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 14/126 (11%) Query: 376 PRPLP---SFCPP-----RRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQL 427 PRP+ + PP LD E+P Q P P P P P L P P P P + Sbjct: 95 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 154 Query: 428 SEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487 + P P + L P P P P P P P P P P P P P P P PAP + Sbjct: 155 AAPVAAPVAVAVLAPAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAPAPAPAPDAA 208 Query: 488 PEPCRE 493 P+ E Sbjct: 209 PQESAE 214 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 9/109 (8%) Query: 403 APRPRLRP--EPCISLEPRPRPLPR-QLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459 A P L P E LE P LP + P P P+P L P P P P P P Sbjct: 103 AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPV 162 Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVP 508 L P P P P P P P+ AP P+P P +P+P P P P Sbjct: 163 AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP------APAPAPAPAPAP 205 Score = 53.1 bits (126), Expect = 7e-07 Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%) Query: 416 LEPRPRPLPRQLSEPCLYP--EPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPC 473 L PRP + +S P L P E L L P +P +P P P P P Sbjct: 93 LAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLA 144 Query: 474 PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPS 533 P P P P P P P +P+P P P P P + +P AP P+ Sbjct: 145 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 204 Query: 534 SYNQGQESG-AGCGPGDVFPERRGQDGHGDQGNAFAGVKG 572 QES G G +RGQ+ DQ +G+ G Sbjct: 205 PDAAPQESAEQGANQG-----QRGQEPLADQ--LHSGISG 237 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%) Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424 AS P P + P P P+ P P + P PAP P P P P P P P Sbjct: 134 ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP 193 Query: 425 RQLSEPCLYPEPLPALRPTPRPVP 448 P P PA P P P Sbjct: 194 A--------PAPAPAPAPAPDAAP 209 >gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo sapiens] Length = 305 Score = 71.2 bits (173), Expect = 2e-12 Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 14/126 (11%) Query: 376 PRPLP---SFCPP-----RRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQL 427 PRP+ + PP LD E+P Q P P P P P L P P P P + Sbjct: 95 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 154 Query: 428 SEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487 + P P + L P P P P P P P P P P P P P P P PAP + Sbjct: 155 AAPVAAPVAVAVLAPAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAPAPAPAPDAA 208 Query: 488 PEPCRE 493 P+ E Sbjct: 209 PQESAE 214 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 9/109 (8%) Query: 403 APRPRLRP--EPCISLEPRPRPLPR-QLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459 A P L P E LE P LP + P P P+P L P P P P P P Sbjct: 103 AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPV 162 Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVP 508 L P P P P P P P+ AP P+P P +P+P P P P Sbjct: 163 AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP------APAPAPAPAPAP 205 Score = 53.1 bits (126), Expect = 7e-07 Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%) Query: 416 LEPRPRPLPRQLSEPCLYP--EPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPC 473 L PRP + +S P L P E L L P +P +P P P P P Sbjct: 93 LAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLA 144 Query: 474 PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPS 533 P P P P P P P +P+P P P P P + +P AP P+ Sbjct: 145 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 204 Query: 534 SYNQGQESG-AGCGPGDVFPERRGQDGHGDQGNAFAGVKG 572 QES G G +RGQ+ DQ +G+ G Sbjct: 205 PDAAPQESAEQGANQG-----QRGQEPLADQ--LHSGISG 237 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%) Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424 AS P P + P P P+ P P + P PAP P P P P P P P Sbjct: 134 ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP 193 Query: 425 RQLSEPCLYPEPLPALRPTPRPVP 448 P P PA P P P Sbjct: 194 A--------PAPAPAPAPAPDAAP 209 >gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo sapiens] Length = 316 Score = 71.2 bits (173), Expect = 2e-12 Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 14/126 (11%) Query: 376 PRPLP---SFCPP-----RRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQL 427 PRP+ + PP LD E+P Q P P P P P L P P P P + Sbjct: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 165 Query: 428 SEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487 + P P + L P P P P P P P P P P P P P P P PAP + Sbjct: 166 AAPVAAPVAVAVLAPAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAPAPAPAPDAA 219 Query: 488 PEPCRE 493 P+ E Sbjct: 220 PQESAE 225 Score = 64.3 bits (155), Expect = 3e-10 Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 9/109 (8%) Query: 403 APRPRLRP--EPCISLEPRPRPLPR-QLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459 A P L P E LE P LP + P P P+P L P P P P P P Sbjct: 114 AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPV 173 Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVP 508 L P P P P P P P+ AP P+P P +P+P P P P Sbjct: 174 AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP------APAPAPAPAPAP 216 Score = 53.1 bits (126), Expect = 7e-07 Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%) Query: 416 LEPRPRPLPRQLSEPCLYP--EPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPC 473 L PRP + +S P L P E L L P +P +P P P P P Sbjct: 104 LAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLA 155 Query: 474 PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPS 533 P P P P P P P +P+P P P P P + +P AP P+ Sbjct: 156 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215 Query: 534 SYNQGQESG-AGCGPGDVFPERRGQDGHGDQGNAFAGVKG 572 QES G G +RGQ+ DQ +G+ G Sbjct: 216 PDAAPQESAEQGANQG-----QRGQEPLADQ--LHSGISG 248 Score = 41.2 bits (95), Expect = 0.003 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%) Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424 AS P P + P P P+ P P + P PAP P P P P P P P Sbjct: 145 ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP 204 Query: 425 RQLSEPCLYPEPLPALRPTPRPVP 448 P P PA P P P Sbjct: 205 A--------PAPAPAPAPAPDAAP 220 >gi|67003568 skin-specific protein 32 [Homo sapiens] Length = 250 Score = 68.9 bits (167), Expect = 1e-11 Identities = 70/222 (31%), Positives = 91/222 (40%), Gaps = 53/222 (23%) Query: 1 MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS 60 MCDQQ+ Q + P CVKG + Q S V CP C Q V+ Sbjct: 1 MCDQQK-QPQFP--PSCVKGSGLGAGQGSNGAS------------VKCPVPCQTQTVCVT 45 Query: 61 DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV 120 APC +QT VK Q CQ TQ + + Q + V+ PCQ+ YV Sbjct: 46 GPAPCPTQT----------YVKYQVPCQ---TQTYVKCPAPCQRTYVKYPTPCQT---YV 89 Query: 121 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST 180 +C A P QT +V+C C Q YV CPAP + Y PA CQ Q Sbjct: 90 KCPA--PCQTTYVKCPTPC-----------QTYVKCPAPCQM-TYIKSPAPCQTQ----- 130 Query: 181 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLR-PSYSSCFPQY 221 C QG+ S C + +A + T Q+ + P + C Y Sbjct: 131 TCYVQGA-SPC-QSYYVQAPASGSTSQYCVTDPCSAPCSTSY 170 Score = 41.6 bits (96), Expect = 0.002 Identities = 70/275 (25%), Positives = 86/275 (31%), Gaps = 93/275 (33%) Query: 84 QAQCQSKTTQVKGQAASQSQTS---SVQSQAPCQSEVSYVQCEASQPVQTCFVECAPVCY 140 Q Q Q + VKG Q S SV+ PCQ++ V A P QT +V+ C Sbjct: 5 QKQPQFPPSCVKGSGLGAGQGSNGASVKCPVPCQTQTVCVTGPAPCPTQT-YVKYQVPCQ 63 Query: 141 TETCYVECPVQNYVPCPA-----PQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQF 195 T+T YV+CP PC P P Q Y PA CQ +Y C Sbjct: 64 TQT-YVKCPA----PCQRTYVKYPTPCQTYVKCPAPCQT------------TYVKCPTPC 106 Query: 196 QSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQ-CQTQGSYGSFTEQHRSRSTSR 254 Q+ C + C Y S +PC Q C QG+ Sbjct: 107 QTYVKCP------------APCQMTYIK--SPAPCQTQTCYVQGA--------------- 137 Query: 255 CLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRC---PR 311 PC S Y+ S YC S P S C PR Sbjct: 138 ---------------------SPCQSYYVQAPASGSTSQYCVTDPCSAPCSTSYCCLAPR 176 Query: 312 ------------RPISSCSQRRGPKCRIEISSPCC 334 RP +C+ C SS CC Sbjct: 177 TFGVSPLRRWIQRP-QNCNTGSSGCCENSGSSGCC 210 Score = 36.2 bits (82), Expect = 0.085 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%) Query: 422 PLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQP-CEHPEPCPRPEPIP 480 P+P Q C+ P P T +P Q + P PC + ++P PC + Sbjct: 34 PVPCQTQTVCV-TGPAPCPTQTYVKYQVPCQTQTYVKCPAPCQRTYVKYPTPCQTY--VK 90 Query: 481 LPAPCPS-----PEPCRETWRSPSPC 501 PAPC + P PC+ + P+PC Sbjct: 91 CPAPCQTTYVKCPTPCQTYVKCPAPC 116 >gi|153792074 proline rich 12 [Homo sapiens] Length = 2036 Score = 66.6 bits (161), Expect = 6e-11 Identities = 54/174 (31%), Positives = 69/174 (39%), Gaps = 27/174 (15%) Query: 389 DQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVP 448 D P +P P P P P L P + P P + P P P PA P P+P P Sbjct: 1420 DGPPLAPAAAVPGPPPLPGL---PSANSNGTPEPPLLEEKPP---PTPPPAPTPQPQPPP 1473 Query: 449 LPRPGQCEIPEPRPCLQPCEH---PEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPN 505 P P Q +P P P + P P P P P P +P+P P P P + +P P Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP------AAAPLAAPP 1527 Query: 506 PVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGPGDVFPERRGQDG 559 P ++P D E P P + QE+ A CG D E G+ G Sbjct: 1528 EEP---------AAPSPEDPELPDTRPLHLAKKQETAAVCGETD---EEAGESG 1569 Score = 52.0 bits (123), Expect = 1e-06 Identities = 50/171 (29%), Positives = 58/171 (33%), Gaps = 12/171 (7%) Query: 329 ISSPCCPRQVPPQRCPVEI-----PPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFC 383 ISS PP P + PP+ + GP P G EP L Sbjct: 1398 ISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP 1457 Query: 384 PPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPT 443 PP P PPP P+P L P P P P P L P P PA+ P+ Sbjct: 1458 PPTPPPAPTPQPQPPPPPPPPQPALPSPP-----PLVAPTPSSPPPPPLPPPPPPAM-PS 1511 Query: 444 PRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRET 494 P P P P P P E PE P P+ L + C ET Sbjct: 1512 PPPPPPPAAAPLAAPPEEPAAPSPEDPE-LPDTRPLHLAKKQETAAVCGET 1561 Score = 37.7 bits (86), Expect = 0.029 Identities = 68/262 (25%), Positives = 87/262 (33%), Gaps = 52/262 (19%) Query: 310 PRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPE 369 P P + +Q +E P P +PP P +P + + S P S Sbjct: 766 PPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPP-PQLLPSVLSHAPSPSPSAS-KVGVHL 823 Query: 370 LRPHVE---PRPLPSFCPPRRLDQCPESPLQR--------CPPPAPRPRLRPEPCISLEP 418 L P P+P P PP P PLQ P AP PRLRPE SL+P Sbjct: 824 LEPATRDGAPQPPPPPPPPP-----PPMPLQLEAHLRSHGLEPAAPSPRLRPEE--SLDP 876 Query: 419 RPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPR------PCLQPCEHPEP 472 P E L AL P P P PG + P P+ Sbjct: 877 -----------PGAMQELLGALEPLP-----PAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920 Query: 473 CPRPEPIPLPAPCPSPEPCRETWRSPSP----CWGPNPVPYPGDLGCHESSPHRLDTEAP 528 P +PL + C ++ RS P +G G G E P Sbjct: 921 TKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGP 980 Query: 529 YCGPSSYN------QGQESGAG 544 GP +Y+ G+ SGAG Sbjct: 981 PPGPPAYDPYGPYCPGRASGAG 1002 Score = 35.0 bits (79), Expect = 0.19 Identities = 40/147 (27%), Positives = 55/147 (37%), Gaps = 24/147 (16%) Query: 334 CPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPE 393 C R+ P R PV P+RR Q+ P + G+S P P P P PP+ + PE Sbjct: 1662 CARK-PWHRPPV---PVRRSGQAKNPVSAGGSSAP---PPKAPAP-----PPK--PETPE 1707 Query: 394 SPLQRCPPPAPRPRLRPEPCISLEP---RPRPLPRQLSEPCLYPEPLPALRPT------- 443 PP PEP +P RP ++ + PL R T Sbjct: 1708 KTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRP 1767 Query: 444 PRPVPLPRPGQCEIPEPRPCLQPCEHP 470 R + +P +P+ RP E P Sbjct: 1768 ERSLATGQPATSRLPKARPTKVKAEPP 1794 Score = 30.8 bits (68), Expect = 3.6 Identities = 40/163 (24%), Positives = 56/163 (34%), Gaps = 16/163 (9%) Query: 141 TETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRAT 200 + T + E + + AP P+Q Y G F T + GS + Sbjct: 35 SRTSHPETDILHRQAYAAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISA 94 Query: 201 CNNYTPQFQLRPSYSSCFPQYRSRT-------------SFSPCVPQCQTQGSYGSFTE-Q 246 + PQ PS SS Q+RS + S +P T S + + Q Sbjct: 95 LESRGPQ--PGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQ 152 Query: 247 HRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSE 289 H + SR P P L L SPP L L+PS+ Sbjct: 153 HPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQ 195 >gi|169211819 PREDICTED: keratin associated protein [Homo sapiens] Length = 517 Score = 66.2 bits (160), Expect = 8e-11 Identities = 136/562 (24%), Positives = 182/562 (32%), Gaps = 126/562 (22%) Query: 24 CSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVSDQAPCQSQTTQ-VKCQSKTKQVK 82 CSS+ F+ V + C ++ SC +C S CQSQT Q V CQ Sbjct: 5 CSSRKCFS---VPATSLCSTEV-----SCGGPICLPSS---CQSQTWQLVTCQDSCGSSS 53 Query: 83 GQAQCQSKTTQVKGQA---------ASQSQTSSVQSQAPCQSEVSYVQCEASQPVQTCFV 133 QC+ + V A S + S Q C + CE S V C+ Sbjct: 54 CGPQCRQPSCPVSSCAQPLCCDPVICEPSCSVSSGCQPVCCEATT---CEPSCSVSNCY- 109 Query: 134 ECAPVCYTET-CYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCG 192 PVC+ T C C V N CQP +T C+ S SSC Sbjct: 110 --QPVCFEATICEPSCSVSN------------------CCQPVCFEATVCEPSCSVSSC- 148 Query: 193 PQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRST 252 ++ C C P C P C + S Sbjct: 149 ----AQPVC---------------CEPAI--------CEPSCSVSSCCQPVGSEATSCQP 181 Query: 253 SRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR 312 C+P + L SC P EP S + PS P C P +P+ CP Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVC-EPSCCQPV----CPTP 236 Query: 313 PISSCSQRRGPKCRIEISSPCCPRQ--VPPQRC------PVEIPPIRRRSQSCGPQPSWG 364 S S + C P C P C PV + P+ SC P PS Sbjct: 237 TCSVTSSCQAVCCDPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEP-PSVP 295 Query: 365 ASCPELRPHVEP--RPL---PSFCPPRRLDQCPESP----LQRCPPPAPRPRLRPEP--- 412 ++C E V +P+ PS C P P P ++RCP P P P Sbjct: 296 STCQEPSCCVSSICQPICSEPSPCSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCR 355 Query: 413 -------------CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459 C PR +P PC + RP RP+ P + Sbjct: 356 PLSCSPGSSASAICRPTCPRTFYIPSSSKRPC---SATISYRPVSRPICRPICSGL-LTY 411 Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAP-CPSPEPCRETWRSPS-----PCWGPNPVPYPGDL 513 +P + + C RP L P C + CR + PS C L Sbjct: 412 RQPYMTSISYRPACYRPCYSILRRPACVTSYSCRPVYFRPSCTESDSCKRDCKKSTSSQL 471 Query: 514 GCHESSPHRLDT--EAPYCGPS 533 C +++P ++D EAP C P+ Sbjct: 472 DCVDTTPCKVDVSEEAP-CQPT 492 Score = 53.9 bits (128), Expect = 4e-07 Identities = 95/396 (23%), Positives = 119/396 (30%), Gaps = 73/396 (18%) Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228 P+ CQ Q CQ SSCGPQ C + C P Sbjct: 32 PSSCQSQTWQLVTCQDSCGSSSCGPQ------CRQPSCPVSSCAQPLCCDPVI------- 78 Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPS 288 C P C +S C P SCS ++P PS Sbjct: 79 -CEPSCSV---------------SSGCQPVCCEATTCEPSCSVSNCYQPVCFEATICEPS 122 Query: 289 EGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKC--------RIEISSPCCPRQVPP 340 N C P + C +SSC+Q P C +SS C P Sbjct: 123 CSVSNCCQPVCFEATVCEPSCS---VSSCAQ---PVCCEPAICEPSCSVSSCCQPVGSEA 176 Query: 341 QRC------PVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPES 394 C P P+ +S C P + C + LPS C P C S Sbjct: 177 TSCQPVLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCT------LPSSCQPV---VCEPS 227 Query: 395 PLQRCPPPAPRPRLR-PEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPG 453 C P P P C ++ P P SE + +P + PV L RP Sbjct: 228 C---CQPVCPTPTCSVTSSCQAVCCDPSPCEPSCSESSIC-QPATCVALVCEPVCL-RPV 282 Query: 454 QC--EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511 C EP C+ P C P+ C P PC SPC P Y Sbjct: 283 CCVQSSCEPPSVPSTCQEPSCCVSSICQPI---CSEPSPCSPAVCVSSPC---QPTCYVV 336 Query: 512 DLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGP 547 C P + + C P S + G + A C P Sbjct: 337 KR-CPSVCPEPVSCPSTSCRPLSCSPGSSASAICRP 371 Score = 52.0 bits (123), Expect = 1e-06 Identities = 90/379 (23%), Positives = 122/379 (32%), Gaps = 67/379 (17%) Query: 5 QQIQCRLPLQQCCVKGPSFCSSQS--PFAQSQVVVQAPCEMQIVDCP-----ASCPVQVC 57 Q + C+ Q V PS CS+ P + VV + C + P +SC C Sbjct: 190 QPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVCEPSCCQPVCPTPTCSVTSSCQAVCC 249 Query: 58 QVSDQAPCQSQTTQVK-CQSKT-KQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQS 115 D +PC+ ++ CQ T + + C V+ S S+ Q + C S Sbjct: 250 ---DPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVS 306 Query: 116 EVSYVQCEASQPVQTCFVECAP-VCYTETCYVECPVQNYVP--CPAPQPVQMYRGRPAVC 172 + C P C+P VC + C C V P CP P RP C Sbjct: 307 SICQPICSEPSP-------CSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCRPLSC 359 Query: 173 QPQGRFSTQCQYQGSYSSCGPQFQSRATCNN--YTPQFQLRPSYSSCFPQYRSRTSFSPC 230 P S C R TC Y P RP S YR S C Sbjct: 360 SPGSSASAIC---------------RPTCPRTFYIPSSSKRP--CSATISYRP-VSRPIC 401 Query: 231 VPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEG 290 P C +Y + TS P R C R C +SY Sbjct: 402 RPICSGLLTY------RQPYMTSISYRP-----ACYRPCYSILRRPACVTSY------SC 444 Query: 291 FPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEIS--SPCCPRQVPPQRCPVEIP 348 P Y P C + S C++++S +PC P + P I Sbjct: 445 RPVYFRPSCTESDSCKRDCKKSTSSQLDCVDTTPCKVDVSEEAPCQPTEAKP------IS 498 Query: 349 PIRRRSQSCGPQPSWGASC 367 P R + + P S A+C Sbjct: 499 PTTREAAAAQPAASKPANC 517 >gi|239745811 PREDICTED: hypothetical protein XP_002343557 [Homo sapiens] Length = 517 Score = 66.2 bits (160), Expect = 8e-11 Identities = 136/562 (24%), Positives = 182/562 (32%), Gaps = 126/562 (22%) Query: 24 CSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVSDQAPCQSQTTQ-VKCQSKTKQVK 82 CSS+ F+ V + C ++ SC +C S CQSQT Q V CQ Sbjct: 5 CSSRKCFS---VPATSLCSTEV-----SCGGPICLPSS---CQSQTWQLVTCQDSCGSSS 53 Query: 83 GQAQCQSKTTQVKGQA---------ASQSQTSSVQSQAPCQSEVSYVQCEASQPVQTCFV 133 QC+ + V A S + S Q C + CE S V C+ Sbjct: 54 CGPQCRQPSCPVSSCAQPLCCDPVICEPSCSVSSGCQPVCCEATT---CEPSCSVSNCY- 109 Query: 134 ECAPVCYTET-CYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCG 192 PVC+ T C C V N CQP +T C+ S SSC Sbjct: 110 --QPVCFEATICEPSCSVSN------------------CCQPVCFEATVCEPSCSVSSC- 148 Query: 193 PQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRST 252 ++ C C P C P C + S Sbjct: 149 ----AQPVC---------------CEPAI--------CEPSCSVSSCCQPVGSEATSCQP 181 Query: 253 SRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR 312 C+P + L SC P EP S + PS P C P +P+ CP Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVC-EPSCCQPV----CPTP 236 Query: 313 PISSCSQRRGPKCRIEISSPCCPRQ--VPPQRC------PVEIPPIRRRSQSCGPQPSWG 364 S S + C P C P C PV + P+ SC P PS Sbjct: 237 TCSVTSSCQAVCCDPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEP-PSVP 295 Query: 365 ASCPELRPHVEP--RPL---PSFCPPRRLDQCPESP----LQRCPPPAPRPRLRPEP--- 412 ++C E V +P+ PS C P P P ++RCP P P P Sbjct: 296 STCQEPSCCVSSICQPICSEPSPCSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCR 355 Query: 413 -------------CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459 C PR +P PC + RP RP+ P + Sbjct: 356 PLSCSPGSSASAICRPTCPRTFYIPSSSKRPC---SATISYRPVSRPICRPICSGL-LTY 411 Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAP-CPSPEPCRETWRSPS-----PCWGPNPVPYPGDL 513 +P + + C RP L P C + CR + PS C L Sbjct: 412 RQPYMTSISYRPACYRPCYSILRRPACVTSYSCRPVYFRPSCTESDSCKRDCKKSTSSQL 471 Query: 514 GCHESSPHRLDT--EAPYCGPS 533 C +++P ++D EAP C P+ Sbjct: 472 DCVDTTPCKVDVSEEAP-CQPT 492 Score = 53.9 bits (128), Expect = 4e-07 Identities = 95/396 (23%), Positives = 119/396 (30%), Gaps = 73/396 (18%) Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228 P+ CQ Q CQ SSCGPQ C + C P Sbjct: 32 PSSCQSQTWQLVTCQDSCGSSSCGPQ------CRQPSCPVSSCAQPLCCDPVI------- 78 Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPS 288 C P C +S C P SCS ++P PS Sbjct: 79 -CEPSCSV---------------SSGCQPVCCEATTCEPSCSVSNCYQPVCFEATICEPS 122 Query: 289 EGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKC--------RIEISSPCCPRQVPP 340 N C P + C +SSC+Q P C +SS C P Sbjct: 123 CSVSNCCQPVCFEATVCEPSCS---VSSCAQ---PVCCEPAICEPSCSVSSCCQPVGSEA 176 Query: 341 QRC------PVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPES 394 C P P+ +S C P + C + LPS C P C S Sbjct: 177 TSCQPVLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCT------LPSSCQPV---VCEPS 227 Query: 395 PLQRCPPPAPRPRLR-PEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPG 453 C P P P C ++ P P SE + +P + PV L RP Sbjct: 228 C---CQPVCPTPTCSVTSSCQAVCCDPSPCEPSCSESSIC-QPATCVALVCEPVCL-RPV 282 Query: 454 QC--EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511 C EP C+ P C P+ C P PC SPC P Y Sbjct: 283 CCVQSSCEPPSVPSTCQEPSCCVSSICQPI---CSEPSPCSPAVCVSSPC---QPTCYVV 336 Query: 512 DLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGP 547 C P + + C P S + G + A C P Sbjct: 337 KR-CPSVCPEPVSCPSTSCRPLSCSPGSSASAICRP 371 Score = 52.0 bits (123), Expect = 1e-06 Identities = 90/379 (23%), Positives = 122/379 (32%), Gaps = 67/379 (17%) Query: 5 QQIQCRLPLQQCCVKGPSFCSSQS--PFAQSQVVVQAPCEMQIVDCP-----ASCPVQVC 57 Q + C+ Q V PS CS+ P + VV + C + P +SC C Sbjct: 190 QPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVCEPSCCQPVCPTPTCSVTSSCQAVCC 249 Query: 58 QVSDQAPCQSQTTQVK-CQSKT-KQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQS 115 D +PC+ ++ CQ T + + C V+ S S+ Q + C S Sbjct: 250 ---DPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVS 306 Query: 116 EVSYVQCEASQPVQTCFVECAP-VCYTETCYVECPVQNYVP--CPAPQPVQMYRGRPAVC 172 + C P C+P VC + C C V P CP P RP C Sbjct: 307 SICQPICSEPSP-------CSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCRPLSC 359 Query: 173 QPQGRFSTQCQYQGSYSSCGPQFQSRATCNN--YTPQFQLRPSYSSCFPQYRSRTSFSPC 230 P S C R TC Y P RP S YR S C Sbjct: 360 SPGSSASAIC---------------RPTCPRTFYIPSSSKRP--CSATISYRP-VSRPIC 401 Query: 231 VPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEG 290 P C +Y + TS P R C R C +SY Sbjct: 402 RPICSGLLTY------RQPYMTSISYRP-----ACYRPCYSILRRPACVTSY------SC 444 Query: 291 FPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEIS--SPCCPRQVPPQRCPVEIP 348 P Y P C + S C++++S +PC P + P I Sbjct: 445 RPVYFRPSCTESDSCKRDCKKSTSSQLDCVDTTPCKVDVSEEAPCQPTEAKP------IS 498 Query: 349 PIRRRSQSCGPQPSWGASC 367 P R + + P S A+C Sbjct: 499 PTTREAAAAQPAASKPANC 517 >gi|83977459 pleckstrin homology-like domain, family A, member 1 [Homo sapiens] Length = 401 Score = 64.3 bits (155), Expect = 3e-10 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 11/87 (12%) Query: 405 RPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCE---IPEPR 461 +P +P+P L+P+P+P P+ P+P P +P P+P P P+P Q P P Sbjct: 306 QPPSQPQPQPQLQPQPQPQPQ--------PQPQPQSQPQPQPQPKPQPQQLHPYPHPHPH 357 Query: 462 PCLQPCEHPEPCPRPEPIPLPAPCPSP 488 P P HP P P P P +P P P P Sbjct: 358 PHSHPHSHPHPHPHPHPHQIPHPHPQP 384 Score = 56.6 bits (135), Expect = 6e-08 Identities = 35/106 (33%), Positives = 50/106 (47%), Gaps = 25/106 (23%) Query: 366 SCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPR 425 S P+ +P ++P+P P P P P+P+ +P+P +P+P+P P+ Sbjct: 309 SQPQPQPQLQPQPQPQ------------------PQPQPQPQSQPQP----QPQPKPQPQ 346 Query: 426 QLSEPCLYPEPLPALRP--TPRPVPLPRPGQCEIPEPRPCLQPCEH 469 QL P +P P P P P P P P P Q P P+P QP H Sbjct: 347 QL-HPYPHPHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPHGH 391 Score = 55.1 bits (131), Expect = 2e-07 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 9/96 (9%) Query: 429 EPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPI-PLPAPCPS 487 +P P+P P L+P P+P P P +P+P QP P+P P+P+ + P P P P Sbjct: 306 QPPSQPQPQPQLQPQPQPQPQP--------QPQPQSQPQPQPQPKPQPQQLHPYPHPHPH 357 Query: 488 PEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRL 523 P + P P P+ +P+P + HRL Sbjct: 358 PHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPHGHRL 393 Score = 47.0 bits (110), Expect = 5e-05 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 1/81 (1%) Query: 458 PEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHE 517 P+P+P LQP P+P P+P+P P P P P+P + P P P+P +P Sbjct: 311 PQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKP-QPQQLHPYPHPHPHPHSHPHSHPHPH 369 Query: 518 SSPHRLDTEAPYCGPSSYNQG 538 PH P+ P S G Sbjct: 370 PHPHPHQIPHPHPQPHSQPHG 390 Score = 39.3 bits (90), Expect = 0.010 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 1/88 (1%) Query: 451 RPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSP-CWGPNPVPY 509 R Q + + +P QP P+ P+P+P P P P P +P + P P P P P+ Sbjct: 296 RQKQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPH 355 Query: 510 PGDLGCHESSPHRLDTEAPYCGPSSYNQ 537 P S PH P+ P + Q Sbjct: 356 PHPHSHPHSHPHPHPHPHPHQIPHPHPQ 383 Score = 32.7 bits (73), Expect = 0.94 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 1/81 (1%) Query: 330 SSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLD 389 S P Q+ PQ P P + +SQ PQP +L P+ P P P P Sbjct: 309 SQPQPQPQLQPQPQPQPQPQPQPQSQP-QPQPQPKPQPQQLHPYPHPHPHPHSHPHSHPH 367 Query: 390 QCPESPLQRCPPPAPRPRLRP 410 P + P P P+P +P Sbjct: 368 PHPHPHPHQIPHPHPQPHSQP 388 >gi|169212026 PREDICTED: keratin associated protein [Homo sapiens] Length = 517 Score = 62.0 bits (149), Expect = 1e-09 Identities = 135/564 (23%), Positives = 180/564 (31%), Gaps = 130/564 (23%) Query: 24 CSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVSDQAPCQSQTTQ-VKCQSKTKQVK 82 CSS+ F+ V + C ++ SC +C S CQSQT Q V CQ Sbjct: 5 CSSRKCFS---VPATSLCSTEV-----SCGGPICLPSS---CQSQTWQLVTCQDSCGSSS 53 Query: 83 GQAQCQSKTTQVKGQA---------ASQSQTSSVQSQAPCQSEVSYVQCEASQPVQTCFV 133 QC+ + V A S + S Q C + CE S V C+ Sbjct: 54 CGPQCRQPSCPVSSCAQPLCCDPVICEPSCSVSSGCQPVCCEATT---CEPSCSVSNCY- 109 Query: 134 ECAPVCYTET-CYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCG 192 PVC+ T C C V N CQP +T C+ S SSC Sbjct: 110 --QPVCFEATICEPSCSVSN------------------CCQPVCFEATICEPSCSVSSC- 148 Query: 193 PQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRST 252 ++ C C P C P C + S Sbjct: 149 ----AQPVC---------------CEPAI--------CEPSCSVSSCCQPVGSEATSCQP 181 Query: 253 SRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR 312 C+P + L SC P EP S + PS P C P +P+ CP Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVC-EPSCCQPV----CPTP 236 Query: 313 PISSCSQRRGPKCRIEISSPCCPRQ--VPPQRC------PVEIPPIRRRSQSCGPQPSWG 364 S S + C P C P C PV + P+ SC P PS Sbjct: 237 TCSVTSSCQAVCCDPSPCEPTCSESSICQPATCVALVCEPVCLRPVCCVQSSCEP-PSVP 295 Query: 365 ASCPELRPHVEP--RPL---PSFCPPRRLDQCPESPLQR-----------CPPPAPRPRL 408 ++C E V +P+ PS C P C SP Q CP P P Sbjct: 296 STCQEPSCCVSSICQPICSEPSPCSPA---VCVSSPCQPTCYVVKRCRSVCPEPVSCPST 352 Query: 409 RPEP------------CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCE 456 P C PR +P PC + RP RP+ P Sbjct: 353 SCRPLSCSPGSSASAICRPTCPRTFYIPSSSKRPC---SATISYRPVSRPICRPICSGL- 408 Query: 457 IPEPRPCLQPCEHPEPCPRPEPIPLPAP-CPSPEPCRETWRSPS-----PCWGPNPVPYP 510 + +P + + C RP L P C + CR + PS C Sbjct: 409 LTYRQPYMTSISYRPACYRPCYSILRRPACVTSYSCRPVYFRPSCTESDSCKRDCKKSTS 468 Query: 511 GDLGCHESSPHRLD-TEAPYCGPS 533 L C +++P ++D +E C P+ Sbjct: 469 SQLDCVDTTPCKVDVSEEGPCQPT 492 Score = 54.7 bits (130), Expect = 2e-07 Identities = 96/396 (24%), Positives = 119/396 (30%), Gaps = 73/396 (18%) Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228 P+ CQ Q CQ SSCGPQ C + C P Sbjct: 32 PSSCQSQTWQLVTCQDSCGSSSCGPQ------CRQPSCPVSSCAQPLCCDPVI------- 78 Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPS 288 C P C +S C P SCS ++P PS Sbjct: 79 -CEPSCSV---------------SSGCQPVCCEATTCEPSCSVSNCYQPVCFEATICEPS 122 Query: 289 EGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKC--------RIEISSPCCPRQVPP 340 N C P I C +SSC+Q P C +SS C P Sbjct: 123 CSVSNCCQPVCFEATICEPSCS---VSSCAQ---PVCCEPAICEPSCSVSSCCQPVGSEA 176 Query: 341 QRC------PVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPES 394 C P P+ +S C P + C + LPS C P C S Sbjct: 177 TSCQPVLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCT------LPSSCQPV---VCEPS 227 Query: 395 PLQRCPPPAPRPRLR-PEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPG 453 C P P P C ++ P P SE + +P + PV L RP Sbjct: 228 C---CQPVCPTPTCSVTSSCQAVCCDPSPCEPTCSESSIC-QPATCVALVCEPVCL-RPV 282 Query: 454 QC--EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511 C EP C+ P C P+ C P PC SPC P Y Sbjct: 283 CCVQSSCEPPSVPSTCQEPSCCVSSICQPI---CSEPSPCSPAVCVSSPC---QPTCYVV 336 Query: 512 DLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGP 547 C P + + C P S + G + A C P Sbjct: 337 KR-CRSVCPEPVSCPSTSCRPLSCSPGSSASAICRP 371 Score = 47.8 bits (112), Expect = 3e-05 Identities = 89/379 (23%), Positives = 120/379 (31%), Gaps = 67/379 (17%) Query: 5 QQIQCRLPLQQCCVKGPSFCSSQS--PFAQSQVVVQAPCEMQIVDCP-----ASCPVQVC 57 Q + C+ Q V PS CS+ P + VV + C + P +SC C Sbjct: 190 QPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVCEPSCCQPVCPTPTCSVTSSCQAVCC 249 Query: 58 QVSDQAPCQSQTTQVK-CQSKT-KQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQS 115 D +PC+ ++ CQ T + + C V+ S S+ Q + C S Sbjct: 250 ---DPSPCEPTCSESSICQPATCVALVCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVS 306 Query: 116 EVSYVQCEASQPVQTCFVECAP-VCYTETCYVECPVQNYV--PCPAPQPVQMYRGRPAVC 172 + C P C+P VC + C C V CP P RP C Sbjct: 307 SICQPICSEPSP-------CSPAVCVSSPCQPTCYVVKRCRSVCPEPVSCPSTSCRPLSC 359 Query: 173 QPQGRFSTQCQYQGSYSSCGPQFQSRATCNN--YTPQFQLRPSYSSCFPQYRSRTSFSPC 230 P S C R TC Y P RP S YR S C Sbjct: 360 SPGSSASAIC---------------RPTCPRTFYIPSSSKRP--CSATISYRP-VSRPIC 401 Query: 231 VPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEG 290 P C +Y + TS P R C R C +SY Sbjct: 402 RPICSGLLTY------RQPYMTSISYRP-----ACYRPCYSILRRPACVTSY------SC 444 Query: 291 FPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEIS--SPCCPRQVPPQRCPVEIP 348 P Y P C + S C++++S PC P + P I Sbjct: 445 RPVYFRPSCTESDSCKRDCKKSTSSQLDCVDTTPCKVDVSEEGPCQPTEAKP------IS 498 Query: 349 PIRRRSQSCGPQPSWGASC 367 P R + + P S A+C Sbjct: 499 PTTREAAAAQPAASKPANC 517 >gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] Length = 1240 Score = 62.0 bits (149), Expect = 1e-09 Identities = 56/165 (33%), Positives = 66/165 (40%), Gaps = 27/165 (16%) Query: 358 GPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLE 417 G QP+ A+C + H + + PR L+Q +P PPP P P L P S E Sbjct: 385 GQQPAAAAACEPV-DHAQSESILKVSQPRALEQQASTP----PPPPPPPLL---PGSSAE 436 Query: 418 PRPRPLPRQLSE-------PCLYPEPLP---ALRPTPRPVPLPRPGQCE-IPEPRPCLQP 466 P P P P L P PLP A+ P P+P P PG CE +P P P L Sbjct: 437 PPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPG 496 Query: 467 CEHPEPCPRPEPIPLP----APCPSPEPCRETWRSPSPCWGPNPV 507 CP P P LP P P P P SP G V Sbjct: 497 L----GCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEV 537 Score = 31.6 bits (70), Expect = 2.1 Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 28/97 (28%) Query: 419 RPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRP-- 476 +PR L +Q S P P P P PL E P P P P P P Sbjct: 410 QPRALEQQASTP-----------PPPPPPPLLPGSSAEPPPP---------PPPPPLPSV 449 Query: 477 --EPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511 + +P AP P P P P+P P P P PG Sbjct: 450 GAKALP-TAPPPPPLPGLGAMAPPAP---PLPPPLPG 482 >gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] Length = 1249 Score = 62.0 bits (149), Expect = 1e-09 Identities = 56/165 (33%), Positives = 66/165 (40%), Gaps = 27/165 (16%) Query: 358 GPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLE 417 G QP+ A+C + H + + PR L+Q +P PPP P P L P S E Sbjct: 385 GQQPAAAAACEPV-DHAQSESILKVSQPRALEQQASTP----PPPPPPPLL---PGSSAE 436 Query: 418 PRPRPLPRQLSE-------PCLYPEPLP---ALRPTPRPVPLPRPGQCE-IPEPRPCLQP 466 P P P P L P PLP A+ P P+P P PG CE +P P P L Sbjct: 437 PPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPG 496 Query: 467 CEHPEPCPRPEPIPLP----APCPSPEPCRETWRSPSPCWGPNPV 507 CP P P LP P P P P SP G V Sbjct: 497 L----GCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEV 537 Score = 31.6 bits (70), Expect = 2.1 Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 28/97 (28%) Query: 419 RPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRP-- 476 +PR L +Q S P P P P PL E P P P P P P Sbjct: 410 QPRALEQQASTP-----------PPPPPPPLLPGSSAEPPPP---------PPPPPLPSV 449 Query: 477 --EPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511 + +P AP P P P P+P P P P PG Sbjct: 450 GAKALP-TAPPPPPLPGLGAMAPPAP---PLPPPLPG 482 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 62.0 bits (149), Expect = 1e-09 Identities = 74/259 (28%), Positives = 102/259 (39%), Gaps = 38/259 (14%) Query: 219 PQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPP--RRFE 276 P R R S SP P + + T R R+ S PPPRR PR SPP RR+ Sbjct: 553 PPTRRRRSPSPAPPPRRRRTP----TPPPRRRTPS---PPPRRRSPSPRRYSPPIQRRYS 605 Query: 277 PC----SSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSP 332 P + P P + + PP+R + +S P++ S ++RR P + Sbjct: 606 PSPPPKRRTASPPPPPKRRASPSPPPKRR--VSHSPPPKQRSSPVTKRRSPSLSSKHRKG 663 Query: 333 CCP-RQVPPQRCPVEIPPIRRRSQSCGPQ-PSWGASCPELR------PHVEPRPLPSFCP 384 P R R P P +R S S P+ P +S P +R P P PS P Sbjct: 664 SSPSRSTREARSP---QPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720 Query: 385 PRRLDQCPE-SPLQRCPPPAPRPRLR----------PEPCISLEPRPRPLPRQLSEPCLY 433 RR+ + PE +++ P+P+ R PEP P P P P Q P Sbjct: 721 IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP-PSPVQSQSPSTN 779 Query: 434 PEPLPALRPTPRPVPLPRP 452 P ++ P P P P Sbjct: 780 WSPAVPVKKAKSPTPSPSP 798 Score = 59.3 bits (142), Expect = 9e-09 Identities = 86/322 (26%), Positives = 114/322 (35%), Gaps = 40/322 (12%) Query: 219 PQYRSRTSFSPCVPQCQTQGSY-GSFTEQHRSRSTSRCLPPPRRLQLFPR-------SCS 270 P R R S SP + ++ S GS + SRS S PP+R PR S S Sbjct: 334 PPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393 Query: 271 PPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSR---CPRRPISSCSQRRGPKCRI 327 PPRR S P + P P++S SR P R ++ +G + R Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPT----PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE 449 Query: 328 EISSPCCPRQVPPQRCPVE-------IPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLP 380 S PR+V + +++R Q + + RP Sbjct: 450 SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR 509 Query: 381 SFCPPRRLDQCPESPLQRCPPPAPRPRLR---PEPCISLEPRPRPLPRQLSEPCLYPEPL 437 S + + R P+PR R + P P P P R+ S P P Sbjct: 510 SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS---PAPP 566 Query: 438 PALRPTPRPVPLPR----PGQCEIPEPR---PCLQPCEHPEPCPR-----PEPIPLPAPC 485 P R TP P P R P + P PR P +Q P P P+ P P P Sbjct: 567 PRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRAS 626 Query: 486 PSPEPCRETWRSPSPCWGPNPV 507 PSP P R SP P +PV Sbjct: 627 PSPPPKRRVSHSPPPKQRSSPV 648 Score = 58.5 bits (140), Expect = 2e-08 Identities = 51/171 (29%), Positives = 70/171 (40%), Gaps = 15/171 (8%) Query: 339 PPQRCPVEIPPIRRRSQSCGPQ---PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESP 395 PP+R PP RRR+ S P+ PS P ++ P P PP+R P P Sbjct: 566 PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSP-----PPKRRTASPPPP 620 Query: 396 LQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPT--PRPVPLPRPG 453 +R P+P P+ R + R P+ ++ S P L + P+ R P+P Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRS-PSLSSKHRKGSSPSRSTREARSPQPN 679 Query: 454 QCEIPEPRP-CLQPCEHPEPCPR---PEPIPLPAPCPSPEPCRETWRSPSP 500 + P PRP Q P P R P +P PS P R R+P P Sbjct: 680 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730 Score = 44.7 bits (104), Expect = 2e-04 Identities = 60/240 (25%), Positives = 75/240 (31%), Gaps = 54/240 (22%) Query: 245 EQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPI 304 E+ R RS SR R P P RR S SY P R +P RR P Sbjct: 272 EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP-------SPRRRPSP- 323 Query: 305 YNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWG 364 +RR P R+ PP R P+RRR +S Sbjct: 324 --------------RRRTPPRRMP----------PPPRHRRSRSPVRRRRRSSASLSGSS 359 Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424 +S R P+ PP+R P +R P A PR R P Sbjct: 360 SSSSSSRSRSPPKK-----PPKRTSSPPRKT-RRLSPSASPPRRRHRP------------ 401 Query: 425 RQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAP 484 P P P PTP+ R + + R + +H R P P P P Sbjct: 402 ----SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457 Score = 30.0 bits (66), Expect = 6.1 Identities = 32/116 (27%), Positives = 42/116 (36%), Gaps = 26/116 (22%) Query: 385 PRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTP 444 PRR SP +R P R R R S PR R R +P Sbjct: 172 PRRRKSRSPSPRRRSSP-VRRERKRSH---SRSPRHRTKSR-----------------SP 210 Query: 445 RPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSP 500 P P + E+PEP ++ E + + +P P P PEP + PSP Sbjct: 211 SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP-----KEPSP 261 >gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo sapiens] Length = 1636 Score = 61.6 bits (148), Expect = 2e-09 Identities = 46/147 (31%), Positives = 56/147 (38%), Gaps = 10/147 (6%) Query: 354 SQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRR-LDQCPESPLQRCPPPAPRPRLRPEP 412 SQ+ GPQP P PH+ P P PP+ P+ + PPP +L P P Sbjct: 964 SQAFGPQPPQ-QPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGP 1022 Query: 413 C-------ISLEPRPRPLPRQLSEPCLYPEPLPALRPT-PRPVPLPRPGQCEIPEPRPCL 464 P P P P Q P L P P+ RP P+ PL G + P Sbjct: 1023 AQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSP 1082 Query: 465 QPCEHPEPCPRPEPIPLPAPCPSPEPC 491 P P P P P+P P P PC Sbjct: 1083 HLVPSPAPSPGPGPVPPRPPAAEPPPC 1109 Score = 57.8 bits (138), Expect = 3e-08 Identities = 57/204 (27%), Positives = 71/204 (34%), Gaps = 62/204 (30%) Query: 348 PPIRRRSQSCGPQPSWGASCPELRPHVEPR---------PLPSFCPPRRLDQCPESPLQR 398 PP+ + PQ S PEL V P P+PS PR Sbjct: 855 PPVAGLPSAPPPQ----FSGPELAMAVRPATTTVDSIQAPIPSHTAPR------------ 898 Query: 399 CPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPA----------------LRP 442 P P P P P PC + P P+PLP + P +P+PA + P Sbjct: 899 -PNPTPAP---PPPCFPVPP-PQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGP 953 Query: 443 TPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCP-----------SPEPC 491 P+P P P P Q P+P P +HP P P LP P P P Sbjct: 954 QPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPP 1013 Query: 492 RETWRSPSPCWGPNP-----VPYP 510 T P P P P +P+P Sbjct: 1014 LHTQLYPGPAQDPLPAHSGALPFP 1037 Score = 52.0 bits (123), Expect = 1e-06 Identities = 65/238 (27%), Positives = 84/238 (35%), Gaps = 35/238 (14%) Query: 297 PPRRSEPIYNSRCPRRPISSCSQRRGPKCRIE------ISSPCCPRQVPPQRCPVEIPPI 350 PPR + P PRR S + P + ++ P P P+ PP Sbjct: 717 PPRPTAP--KPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPS 774 Query: 351 RRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRP 410 S S GP P + + P P ++ P +L Q P +P P AP P L P Sbjct: 775 PFPS-STGPGPHYLSG---------PLPPGTYSGPTQLIQ-PRAPGPHAMPVAPGPALYP 823 Query: 411 EPC----ISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQP 466 P + L PR P +S P + P P + P P G RP Sbjct: 824 APAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTT 883 Query: 467 CEHPE-PCPR---PEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSP 520 + + P P P P P PAP P PC P P P P PY G + P Sbjct: 884 VDSIQAPIPSHTAPRPNPTPAP---PPPC-----FPVPPPQPLPTPYTYPAGAKQPIP 933 Score = 33.1 bits (74), Expect = 0.72 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 17/124 (13%) Query: 393 ESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPE-PLPALRPTPRPVPLPR 451 E LQR P P +P S+ + LP+ + L + P+ +++ T + + Sbjct: 1454 EQVLQRHGVPPP---CKPLASASISQKNH-LPQDSQDLVLGGDVPISSIQATIAKLSIRP 1509 Query: 452 PGQCEIP--------EPRPCLQPCEHPE--PCPRPEPIPLPAPCP-SPEPCRETWRSPSP 500 PG E P EP P L P PE P P P PL +P P +P+P E +P Sbjct: 1510 PGGLESPVASLPGPAEP-PGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAP 1568 Query: 501 CWGP 504 GP Sbjct: 1569 SSGP 1572 Score = 31.2 bits (69), Expect = 2.7 Identities = 16/43 (37%), Positives = 19/43 (44%) Query: 375 EPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLE 417 E P+PS PP PE+P + PP P P SLE Sbjct: 1536 ESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSLE 1578 >gi|154800453 tastin isoform 1 [Homo sapiens] Length = 778 Score = 60.8 bits (146), Expect = 3e-09 Identities = 69/204 (33%), Positives = 76/204 (37%), Gaps = 41/204 (20%) Query: 359 PQPSWGASC--PELRPHVEPRPLPSFCPPRRLDQCPESPLQR---CPPPAPRPRLRP-EP 412 P+P C P+ P EP P +FC R + PE LQ P P P RP E Sbjct: 501 PKPCLPEECGEPQPCPPAEPGPPEAFC--RSEPEIPEPSLQEQLEVPEPYPPAEPRPLES 558 Query: 413 CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEP 472 C EP RQ E PEP P P RP+ + EIPE Q E PEP Sbjct: 559 CCRSEPEIPESSRQ--EQLEVPEPCPPAEP--RPLESYCRIEPEIPESSRQEQ-LEVPEP 613 Query: 473 CPRPEPIPL----------PAPCP-----SPEPC----RETWRSPSPC---WGPNPVPYP 510 CP EP PL P PCP + EPC R S PC W P Sbjct: 614 CPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWA------P 667 Query: 511 GDLGCHESSPHRLDTEAPYCGPSS 534 SS H L P C S Sbjct: 668 ATTSLIFSSQHPLCASPPICSLQS 691 Score = 55.1 bits (131), Expect = 2e-07 Identities = 52/136 (38%), Positives = 57/136 (41%), Gaps = 20/136 (14%) Query: 379 LPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPR-PRPLPRQLSEPCLYPEPL 437 LP C P ++C E Q CPP P P PE EP P P L E PEP Sbjct: 500 LPKPCLP---EECGEP--QPCPPAEPGP---PEAFCRSEPEIPEP---SLQEQLEVPEPY 548 Query: 438 PALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPC----PSPEPCR- 492 P P RP+ + EIPE Q E PEPCP EP PL + C PE R Sbjct: 549 PPAEP--RPLESCCRSEPEIPESSRQEQ-LEVPEPCPPAEPRPLESYCRIEPEIPESSRQ 605 Query: 493 ETWRSPSPCWGPNPVP 508 E P PC P P Sbjct: 606 EQLEVPEPCPPAEPGP 621 Score = 46.2 bits (108), Expect = 8e-05 Identities = 57/178 (32%), Positives = 70/178 (39%), Gaps = 44/178 (24%) Query: 280 SSYLP-LRPSEGFPNYCTPPRRSEPIYNSRCPRR----PISSCSQRRGPKC-------RI 327 +S+LP L G P C P EP CP P + C R P+ ++ Sbjct: 488 TSHLPGLLKHSGLPKPCLPEECGEP---QPCPPAEPGPPEAFC--RSEPEIPEPSLQEQL 542 Query: 328 EISSPCCPRQVPPQ----RCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFC 383 E+ P P + P R EIP R+ Q P+P P EPRPL S+C Sbjct: 543 EVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPC---------PPAEPRPLESYC 593 Query: 384 PPRRLDQCPESPLQR-------CPPPAPRPRLRPEPCISLEPRPRPLPR---QLSEPC 431 R + PES Q CPP P P L+P P P P PR SEPC Sbjct: 594 --RIEPEIPESSRQEQLEVPEPCPPAEPGP-LQPSTQGQSGP-PGPCPRVELGASEPC 647 Score = 35.4 bits (80), Expect = 0.14 Identities = 29/99 (29%), Positives = 36/99 (36%), Gaps = 17/99 (17%) Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPN---PVPYPGDLGCH 516 P+PCL PE C P+P P P P CR P P P PYP Sbjct: 501 PKPCL-----PEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYP------ 549 Query: 517 ESSPHRLDT---EAPYCGPSSYNQGQESGAGCGPGDVFP 552 + P L++ P SS + E C P + P Sbjct: 550 PAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRP 588 >gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens] Length = 1711 Score = 59.7 bits (143), Expect = 7e-09 Identities = 64/227 (28%), Positives = 81/227 (35%), Gaps = 25/227 (11%) Query: 323 PKCRIEISSPCCPRQVPPQ-RCPVEIPPIRRRSQSCGPQ--PSWGASCPELRPHVEPRPL 379 P C S P VP + P+ +P S Q S A P L P P Sbjct: 202 PICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPA 261 Query: 380 PSFCPPRRLDQCPESPLQRC--PPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPL 437 P P D P S P PA P P P + P P +P L P+ Sbjct: 262 PPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPV 321 Query: 438 P------ALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP--LPAPCPSPE 489 P L P P PV P P P P P P P P P +PA P+P Sbjct: 322 PPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPV 381 Query: 490 PCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYN 536 P +P+P + P P P P ++P + T AP P+S++ Sbjct: 382 PA----PTPAPIFTPAPTPMPA------ATPAAIPTSAPI--PASFS 416 Score = 57.4 bits (137), Expect = 4e-08 Identities = 56/213 (26%), Positives = 71/213 (33%), Gaps = 10/213 (4%) Query: 329 ISSPCCPRQVPPQRCPVEIPPIRRRSQSC-GPQPSWGASCPELRPHVEPRPLPSFCPPRR 387 + +P CP P +P + S P P G ++ V P P P P Sbjct: 199 LPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSV-PAPSPPLAPVPA 257 Query: 388 LDQCPESP----LQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPT 443 L P S P L P P + P PL P P P L Sbjct: 258 LAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALI 317 Query: 444 PRPVPLPRPGQCEIPEPRPCL--QPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPC 501 PVP P P P P L P P P P +P+P P PS P + + P Sbjct: 318 QAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP--PSTPTLIPA 375 Query: 502 WGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSS 534 + P PVP P +P + P P+S Sbjct: 376 FAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTS 408 Score = 57.0 bits (136), Expect = 5e-08 Identities = 41/126 (32%), Positives = 44/126 (34%), Gaps = 8/126 (6%) Query: 368 PELRPHVEPRPLPSFCPPRRLDQCPESP------LQRCPPP--APRPRLRPEPCISLEPR 419 P P P +P PP L Q P P L P P AP P P + Sbjct: 296 PLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSV 355 Query: 420 PRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPI 479 P P P S P P +PA PTP P P P P P P P P P P P Sbjct: 356 PMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASF 415 Query: 480 PLPAPC 485 L C Sbjct: 416 SLSRVC 421 Score = 43.9 bits (102), Expect = 4e-04 Identities = 43/172 (25%), Positives = 58/172 (33%), Gaps = 17/172 (9%) Query: 301 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ 360 S P+ S P+ + + GP + +S+P P PV PP+ P Sbjct: 272 SNPLSVSASVLVPVPASAPPSGP---VPLSAPA----PAPLSVPVSAPPLALIQAPVPPS 324 Query: 361 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPR- 419 P P + P +P+ PP P P P P P P P +L P Sbjct: 325 APTLVLAPVPTPVLAP--MPASTPPA----APAPP--SVPMPTPTPSSGPPSTPTLIPAF 376 Query: 420 -PRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHP 470 P P+P P P P P TP +P P R C + P Sbjct: 377 APTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAP 428 Score = 32.7 bits (73), Expect = 0.94 Identities = 30/123 (24%), Positives = 39/123 (31%), Gaps = 24/123 (19%) Query: 402 PAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPR 461 P P P P P + P S P + PL P P +P +P P Sbjct: 198 PLPAPICPPAPGSASVPH--------SVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249 Query: 462 PCLQPCEHPEPCPRPEP----------------IPLPAPCPSPEPCRETWRSPSPCWGPN 505 P L P P P P +P+PA P P + +P+P P Sbjct: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPV 309 Query: 506 PVP 508 P Sbjct: 310 SAP 312 Score = 30.8 bits (68), Expect = 3.6 Identities = 29/114 (25%), Positives = 36/114 (31%), Gaps = 6/114 (5%) Query: 415 SLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCP 474 + P P P+ P +P P VP P P + P P P P Sbjct: 195 NFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLV----PVQVATSVPAPSP 250 Query: 475 RPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAP 528 P+P AP P P + +P VP P S P L AP Sbjct: 251 PLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPA--SAPPSGPVPLSAPAP 302 >gi|239744133 PREDICTED: hypothetical protein [Homo sapiens] Length = 375 Score = 58.5 bits (140), Expect = 2e-08 Identities = 65/268 (24%), Positives = 93/268 (34%), Gaps = 31/268 (11%) Query: 41 CEMQIVDCPASCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQS---KTTQVKG 96 C Q ++C Q Q S CQS T+ C ++ ++ CQS +T Sbjct: 18 CSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRISSTCSCQSSGTSSTSCSC 77 Query: 97 QAASQSQTSSVQSQAPCQSEVSY--------VQCEAS---------QPVQTCFVECAPVC 139 Q++ S T S QS + S+ +C++S Q +T C+ C Sbjct: 78 QSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRTSSTSCSCQSSRTSSTSCS--C 135 Query: 140 YTETCYVECPVQNYVPCPAPQPVQMYR-GRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSR 198 + C Q Q R CQ G ST C +Q S +S QS Sbjct: 136 QSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSS 195 Query: 199 ATCN-NYTPQFQLRPSYSSCFPQYRSRTSFS------PCVPQCQTQGSYGSFTEQHRSRS 251 T + +Y+ Q S SC S TS S CQ+ G+ + SR+ Sbjct: 196 GTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRT 255 Query: 252 TSRCLPPPRRLQLFPRSCSPPRRFEPCS 279 +S C R SC CS Sbjct: 256 SSTCSCQSSRTSSTSCSCQSSGTSSTCS 283 Score = 54.3 bits (129), Expect = 3e-07 Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 26/199 (13%) Query: 60 SDQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSE--- 116 S CQS T C ++ Q CQS T + Q+S + S CQS Sbjct: 15 SSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTS---STSCNWQSSRISSTCSCQSSGTS 71 Query: 117 VSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQG 176 + C++S+ TC + + T + + C + + CQ Sbjct: 72 STSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRT----SSTSCSCQSSR 127 Query: 177 RFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQT 236 ST C Q S +S +TC+ T R S +SC Y+S + S C CQ+ Sbjct: 128 TSSTSCSCQSSRTS--------STCSCQTS----RTSSTSC--SYQSSRTSSTC--SCQS 171 Query: 237 QGSYGSFTEQHRSRSTSRC 255 G+ + SR++S C Sbjct: 172 SGTSSTSCNWQSSRTSSTC 190 Score = 53.9 bits (128), Expect = 4e-07 Identities = 61/231 (26%), Positives = 85/231 (36%), Gaps = 35/231 (15%) Query: 51 SCPVQVCQVSDQAPCQ-SQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109 SC Q + S CQ S+T+ C ++ + CQS T S+TSS S Sbjct: 132 SCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCS 191 Query: 110 -QAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGR 168 Q+ S SY C++S TC + + T C Q+ Sbjct: 192 CQSSGTSSTSY-SCQSSGTSSTCSCQS-----SGTSSTSCSCQS-----------SGTSS 234 Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228 CQ G ST C +Q S +S S +C + R S +SC Q S + S Sbjct: 235 TCSCQSSGTSSTSCSWQSSRTS------STCSCQS------SRTSSTSCSCQ--SSGTSS 280 Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCS 279 C CQ+ G+ + SR++S C R SC R CS Sbjct: 281 TC--SCQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCS 329 Score = 53.1 bits (126), Expect = 7e-07 Identities = 53/191 (27%), Positives = 75/191 (39%), Gaps = 12/191 (6%) Query: 51 SCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109 SC Q + S CQS T+ C ++ + CQS T + S TSS S Sbjct: 155 SCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCS 214 Query: 110 QAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRP 169 + + C++S TC + + T + + C + + Sbjct: 215 CQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSRT----SSTS 270 Query: 170 AVCQPQGRFST-QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228 CQ G ST CQ G+ SS QS T + + QF R S +SC Q SRTS S Sbjct: 271 CSCQSSGTSSTCSCQSSGT-SSTSCSCQSSRTSSTCSCQFS-RTSSTSCSCQ-SSRTS-S 326 Query: 229 PCVPQCQTQGS 239 C CQ+ G+ Sbjct: 327 TC--SCQSSGT 335 Score = 42.0 bits (97), Expect = 0.002 Identities = 46/167 (27%), Positives = 64/167 (38%), Gaps = 15/167 (8%) Query: 98 AASQSQTSSVQSQAPCQSEV--SYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVP 155 A Q + SS S CQS S C++SQ TC + + T + + + Sbjct: 7 ACKQHRASS--SSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRISSTCS 64 Query: 156 CPAP-------QPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQF 208 C + CQ G ST C +Q S +S + QS T + Sbjct: 65 CQSSGTSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRTSSTSCSCQ 124 Query: 209 QLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC 255 R S +SC Q SRTS S C CQT + + SR++S C Sbjct: 125 SSRTSSTSCSCQ-SSRTS-STC--SCQTSRTSSTSCSYQSSRTSSTC 167 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/158 (24%), Positives = 55/158 (34%), Gaps = 22/158 (13%) Query: 51 SCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109 SC Q S CQS T+ C ++ + CQS T + S TSS S Sbjct: 224 SCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSRTSSTSCSCQSSGTSSTCS 283 Query: 110 QAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRP 169 + + C++S+ TC + ++ T C Q+ Sbjct: 284 CQSSGTSSTSCSCQSSRTSSTCSCQ-----FSRTSSTSCSCQS-----------SRTSST 327 Query: 170 AVCQPQGRFSTQC---QYQGSYSSCGPQFQ--SRATCN 202 CQ G ST C S +SC +F S +CN Sbjct: 328 CSCQSSGTSSTSCICWSSGTSSTSCSGRFSGTSSTSCN 365 Score = 39.7 bits (91), Expect = 0.008 Identities = 54/231 (23%), Positives = 79/231 (34%), Gaps = 37/231 (16%) Query: 22 SFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQV---------CQ---VSDQAPCQSQ- 68 S CS QS S C Q ++C Q CQ S CQS Sbjct: 165 STCSCQSSGTSS-----TSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSG 219 Query: 69 TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYVQCEASQPV 128 T+ C ++ CQS T + S+TSS S ++ + C++S Sbjct: 220 TSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSRTSSTSCSCQSSGTS 279 Query: 129 QTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSY 188 TC + + T C Q+ CQ ST C Q S Sbjct: 280 STCSCQSSGTSSTS-----CSCQS-----------SRTSSTCSCQFSRTSSTSCSCQSSR 323 Query: 189 SSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGS 239 +S QS T + + S +SC ++ S TS + C C++ G+ Sbjct: 324 TSSTCSCQSSGTSSTSCICWSSGTSSTSCSGRF-SGTSSTSC--NCRSSGT 371 >gi|33186895 selenoprotein V [Homo sapiens] Length = 346 Score = 58.5 bits (140), Expect = 2e-08 Identities = 51/162 (31%), Positives = 61/162 (37%), Gaps = 19/162 (11%) Query: 378 PLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPL 437 P+ + P SPL P PA P L P P ++ PR P P P P P+ Sbjct: 42 PIRTLTPVLTPSPAGTSPLVLTPAPAQIPTLVPTPALARIPRLVPPPAPAWIPTPVPTPV 101 Query: 438 PALRPTPRP-----------VPLPRPGQ------CEIPEPRPCLQPCEHPEPCPRPEP-I 479 P PTP P VP P P Q +P L P +P P P P + Sbjct: 102 PVRNPTPVPTPARTLTPPVRVPAPAPAQLLAGIRAALPVLDSYLAPALPLDPPPEPAPEL 161 Query: 480 P-LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSP 520 P LP P P P + S S GP P P P +SP Sbjct: 162 PLLPEEDPEPAPSLKLIPSVSSEAGPAPGPLPTRTPLAANSP 203 Score = 47.0 bits (110), Expect = 5e-05 Identities = 42/138 (30%), Positives = 53/138 (38%), Gaps = 29/138 (21%) Query: 398 RCPPP--APRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEP--LPALRPTPRPVPLPRPG 453 R P P P P P +L P P P S L P P +P L PTP +PR Sbjct: 26 RTPTPLRTPTPVRTRTPIRTLTPVLTPSPAGTSPLVLTPAPAQIPTLVPTPALARIPRL- 84 Query: 454 QCEIPEPRPCLQPCEHPEPCP--RPEPIPLPA---------PCPSPE----------PCR 492 +P P P P P P P P P+P PA P P+P P Sbjct: 85 ---VPPPAPAWIPTPVPTPVPVRNPTPVPTPARTLTPPVRVPAPAPAQLLAGIRAALPVL 141 Query: 493 ETWRSPSPCWGPNPVPYP 510 +++ +P+ P P P P Sbjct: 142 DSYLAPALPLDPPPEPAP 159 Score = 42.7 bits (99), Expect = 0.001 Identities = 74/279 (26%), Positives = 98/279 (35%), Gaps = 40/279 (14%) Query: 233 QCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFP 292 Q +T + T ST P P R R+ +P R P L P+ P Sbjct: 4 QARTPAPSSARTSTSVRASTPTRTPTPLRTPTPVRTRTPIRTLTPV----LTPSPAGTSP 59 Query: 293 NYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIP-PIR 351 TP P + P ++ + P I +P P VP R P +P P R Sbjct: 60 LVLTPAPAQIP---TLVPTPALARIPRLVPPPAPAWIPTPV-PTPVPV-RNPTPVPTPAR 114 Query: 352 RRSQSC---GPQPSW-----GASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPA 403 + P P+ A+ P L ++ P LP PP + PE PL P Sbjct: 115 TLTPPVRVPAPAPAQLLAGIRAALPVLDSYLAPA-LPLDPPP---EPAPELPLLPEEDPE 170 Query: 404 PRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPC 463 P P L+ P +S E P P P P P P L T R P + +P Sbjct: 171 PAPSLKLIPSVSSEAGPAPGPLPTRTPLAANSPGPTLDFTFR----ADPSAIGLADP--- 223 Query: 464 LQPCEHPEPCPRPEPIPLPAPCPSP---EPCRETWRSPS 499 P P P P P+ PS + C ET+ S S Sbjct: 224 --------PIPSPVPSPILGTIPSAISLQNCTETFPSSS 254 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 58.2 bits (139), Expect = 2e-08 Identities = 92/365 (25%), Positives = 119/365 (32%), Gaps = 61/365 (16%) Query: 157 PAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQ----------SRATCNNYTP 206 P P P PA P +T S P Q S+A + TP Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375 Query: 207 QFQLRPSYSSCFPQYRSRTSFSP---------CVPQCQTQGSYGSFTEQHRS-------R 250 Q PS + P + SP + Q S GS T Q R Sbjct: 376 PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435 Query: 251 STSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPS--EGFPNYCTP----PRRSEPI 304 T L P R P SPP + + PL+ S +P P ++ Sbjct: 436 QTQASLTSPSRPASTPPD-SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494 Query: 305 YNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWG 364 S P+ P+SS +E S P + + PP+ S P P Sbjct: 495 LASHSPQAPLSSLIMPP-----LETQSSLAPPSLQTPPASLTTPPLENLP-SLAPPPLQT 548 Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424 AS P PH+E P P+ CP + PP+P PE S+ P P Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQA-------------PPSPLTTPPPETPSSIATPPPQAP 595 Query: 425 RQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAP 484 L+ P L P P L P P P + P P L P + P P P P P Sbjct: 596 PALASPPLQGLPSPPLSPLATPPP-------QAP-PXLALPPLQAP-PSPPASPPLSPLA 646 Query: 485 CPSPE 489 PSP+ Sbjct: 647 TPSPQ 651 Score = 53.5 bits (127), Expect = 5e-07 Identities = 85/302 (28%), Positives = 102/302 (33%), Gaps = 53/302 (17%) Query: 257 PPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISS 316 PPP P S P P S S P PS+ P+ PP + P + P P ++ Sbjct: 667 PPPSPPVQAPFS---PPASPPVSPSATP--PSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721 Query: 317 CSQRR-----GPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELR 371 + P ++ S P P P P +PP+ P PS AS P + Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLP-MS 779 Query: 372 PHVEPRPL--PSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSE 429 P +P P P+ P Q SP P AP P L P P L+ Sbjct: 780 PLAKPPPQAPPALATPPL--QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837 Query: 430 PCLYPEPLPALRPT---PRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCP 486 P L P P PT PR P P P + PR L AP P Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGP-DTSVSGPRLTL----------------ALAPGP 880 Query: 487 SPEPCRETWRSPSPCW-GPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGC 545 P P RSPS GP DL H SS E Y+ G E GA Sbjct: 881 PPPPS----RSPSSTLSGP-------DLAGHSSSATSTPEEL-----RGYDSGPEGGAAA 924 Query: 546 GP 547 P Sbjct: 925 SP 926 Score = 49.7 bits (117), Expect = 7e-06 Identities = 92/359 (25%), Positives = 127/359 (35%), Gaps = 50/359 (13%) Query: 196 QSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC 255 Q+ ++ +++PQ P S P +++S +P P QT + S T S Sbjct: 490 QALSSLASHSPQ---APLSSLIMPPLETQSSLAP--PSLQTPPA--SLTTPPLENLPSLA 542 Query: 256 LPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPN-YCTPPRRSEPIYNSRCPRRPI 314 PPP + P + +P PC + P + P+ TPP + + P+ P Sbjct: 543 -PPPLQTASAPLT-TPHLETPPCPAPC----PLQAPPSPLTTPPPETPSSIATPPPQAPP 596 Query: 315 SSCSQRRGPKCRIEISSPCCPRQVPPQRCP--VEIPPIRRRSQSCGPQPSWGASCPELRP 372 + S P + S P P PP + P + +PP++ PS AS P L P Sbjct: 597 ALAS----PPLQGLPSPPLSPLATPPPQAPPXLALPPLQA-------PPSPPAS-PPLSP 644 Query: 373 HVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCL 432 P P L Q P SP PP+P + P S P P + P L Sbjct: 645 LATPSPQAPNALAVHLLQAPFSP-----PPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699 Query: 433 YPEPL---------PALRPTPRPVPLPRPGQCEIP---EPRPCLQPCEHPEPCPRPEPIP 480 PL P + P+ P P P P P P P P P P P Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759 Query: 481 LPAPCPSPEPCRETWRSP-SPCWGPNPVPYPG----DLGCHESSPHRLDTEAPYCGPSS 534 L A P P P SP P P P L S P +AP+ +S Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 818 Score = 45.4 bits (106), Expect = 1e-04 Identities = 70/244 (28%), Positives = 88/244 (36%), Gaps = 47/244 (19%) Query: 297 PPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQS 356 P + P + PR+ +SS S+ + SP R+ P ++ P R S S Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTE-----PSPAARRR-PSAGGGLQRPASRSLSSS 245 Query: 357 CGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISL 416 P S S P R PR P P Q P P LRP Sbjct: 246 ATPLSSPARSGPSARG-----------TPR----APAHPSQ--PKPKGLQALRP------ 282 Query: 417 EPRPRPLPRQLSEPCLYP-EPLPALRPTP-----RPVPLPRPGQCEIPEPRPCLQPCEHP 470 P+ P PR+ + P L P P P+P RPVP P +P P P Sbjct: 283 -PQVTP-PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP-------P 333 Query: 471 EPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYC 530 P P P+PL P PS P +T SP P P+ P P +P L T P Sbjct: 334 SP-PLATPLPLAPPSPSAPPSLQTLPSP-PATPPSQAP-PSMTTPPMQAPPSLQTIPPIQ 390 Query: 531 GPSS 534 P S Sbjct: 391 VPHS 394 Score = 40.0 bits (92), Expect = 0.006 Identities = 66/285 (23%), Positives = 80/285 (28%), Gaps = 63/285 (22%) Query: 267 RSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCR 326 R PP + LP P P PP S P P P + SQ Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374 Query: 327 IEISSPCCPRQVPPQRCP-------VEIPPIRRRSQS--------------------CGP 359 + +P + +PP + P ++ PP S P Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434 Query: 360 QPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRP--------- 410 + + + RP P P P L P PLQ PA P P Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASP--PLQTSLSPAVSPLSSPLTIHPLQAL 492 Query: 411 ---------EPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPR 461 P SL P L+ P L P P +P P Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP--------- 543 Query: 462 PCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNP 506 P LQ P P E P PAPCP P PSP P P Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAP-------PSPLTTPPP 581 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 58.2 bits (139), Expect = 2e-08 Identities = 89/329 (27%), Positives = 119/329 (36%), Gaps = 52/329 (15%) Query: 256 LPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR--- 312 LPPP L P + SPP P S+S P P PP S P ++ + Sbjct: 401 LPPP---PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESP 457 Query: 313 -PI--SSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCG-PQPSWGASCP 368 P+ ++CS++RG P P QR E S P PS P Sbjct: 458 PPVVPATCSRKRGR-----------PPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGP 506 Query: 369 -ELRPHVEPRP------LPSFCPP------RRLDQCPESPLQRCPPPAPRPRLRP--EPC 413 E P V P+ + F P R+ + P + PP P+ + P P Sbjct: 507 PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPP 566 Query: 414 ISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEP--RPCLQPCEHPE 471 I+ P P+P+ EP P P A P PVPLP + + EP R E P Sbjct: 567 ITTSP---PVPQ---EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620 Query: 472 PCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCG 531 P P P P P P+P P+P + R P P P L +ES P G Sbjct: 621 PPPAPPPPPAPSPPPAP---ATSSRRPLLLRAPQFTPSEAHLKIYESV-----LTPPPLG 672 Query: 532 PSSYNQGQESGAGCGPGDVFPERRGQDGH 560 + + A P + P G+ H Sbjct: 673 APEAPEPEPPPADDSPAEPEPRAVGRTNH 701 Score = 43.9 bits (102), Expect = 4e-04 Identities = 68/247 (27%), Positives = 85/247 (34%), Gaps = 25/247 (10%) Query: 267 RSCSPPRRF---EPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGP 323 R PRRF +P + + P P +PP EP PR P + P Sbjct: 538 RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597 Query: 324 KCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPL---- 379 + R I R R E+PP P P S P RPL Sbjct: 598 EKRRSILREPTFRWTSLTR---ELPP-----PPPAPPPPPAPSPPPAPATSSRRPLLLRA 649 Query: 380 PSFCPPRRLDQCPESPLQRCP---PPAPRPRLRPEPCISLEPRPRPLPR--QLSEPCLYP 434 P F P + ES L P P AP P P EP PR + R LS P P Sbjct: 650 PQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAP 709 Query: 435 EPLPALRP--TPRPVPLPRPG---QCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPE 489 ++ +P P G Q ++ +P LQ P+ P P+P P P P Sbjct: 710 VVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQM 769 Query: 490 PCRETWR 496 P E R Sbjct: 770 PPLEKAR 776 Score = 40.0 bits (92), Expect = 0.006 Identities = 53/181 (29%), Positives = 66/181 (36%), Gaps = 30/181 (16%) Query: 270 SPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPK----C 325 SP EP PL P P R PI N P RP S + P+ Sbjct: 1807 SPAPSSEPPGGEDPPLDTDVLVPG---APERHSPIQNLDPPLRPDSGSAPPPAPRSFSGA 1863 Query: 326 RIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPP 385 RI++ + P R P+ S GP PS G S L H+ P F P Sbjct: 1864 RIKVPN------YSPSRRPLG-------GVSFGPLPSPG-SPSSLTHHIPTVGDPDFPAP 1909 Query: 386 RRLDQCPESPLQRCPPPA--------PRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPL 437 R + P SPL PPP+ P+LR P S+ P +L+ P P P Sbjct: 1910 PRRSRRP-SPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968 Query: 438 P 438 P Sbjct: 1969 P 1969 Score = 35.0 bits (79), Expect = 0.19 Identities = 52/176 (29%), Positives = 67/176 (38%), Gaps = 23/176 (13%) Query: 248 RSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPL-------RPSEG----FPNYCT 296 R S +R LPPP P + SPP P +SS PL PSE + + T Sbjct: 610 RWTSLTRELPPPPPAPPPPPAPSPPP--APATSSRRPLLLRAPQFTPSEAHLKIYESVLT 667 Query: 297 PPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPV--EIPPIRRRS 354 PP P P P P+ + PR P PV E+ P + Sbjct: 668 PPPLGAPEAPEPEP-PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726 Query: 355 QSCGPQPSWGASCP--ELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRL 408 S GPQ P L+ + P+ LP PP+ Q P SP Q PP + R+ Sbjct: 727 LSNGPQTQAQLLQPLQALQTQLLPQALP---PPQPQLQPPPSPQQM--PPLEKARI 777 Score = 32.7 bits (73), Expect = 0.94 Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 10/76 (13%) Query: 447 VPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAP--CPSPEPCRETWRSPSPCWGP 504 +P + ++P P P P P P P P P P P CP P P SP P P Sbjct: 391 MPAAEKEEAKLPPP-PLTPPAPSPPP-PLPPPSTSPPPPLCPPPPPP----VSPPPL--P 442 Query: 505 NPVPYPGDLGCHESSP 520 +P P P ES P Sbjct: 443 SPPPPPAQEEQEESPP 458 >gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] Length = 280 Score = 57.8 bits (138), Expect = 3e-08 Identities = 56/223 (25%), Positives = 71/223 (31%), Gaps = 16/223 (7%) Query: 314 ISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPH 373 +SS + GP E+ +P PP P P + C S P L P Sbjct: 34 VSSVGEMTGPYGPREMGTPTLTPSSPPTLTPSNTPTL----TPCSTPTLTPCSTPTLTPS 89 Query: 374 VEPRPLPSFCPPRRLDQCPESPLQRCP--PPAPRPRLRPEPCISLEPRPRPLPRQLSEPC 431 P PS P P P P+ P L P +L P P + S P Sbjct: 90 NTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPT 149 Query: 432 LYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPC 491 L P P L P+ P P P P L P P P P+ P+ P Sbjct: 150 LTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPS 209 Query: 492 RETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSS 534 +PS P +P S+P + P PSS Sbjct: 210 STPTLTPSNT--PTLIP--------SSTPTLTPSSTPTLTPSS 242 Score = 53.5 bits (127), Expect = 5e-07 Identities = 53/204 (25%), Positives = 65/204 (31%), Gaps = 26/204 (12%) Query: 325 CRIEISSPCCPRQVPPQRCPVEIP---PIRRRSQSCGPQPS-----WGASCPELRPHVEP 376 C +PC + P P P P S + PS +S P L P P Sbjct: 73 CSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTP 132 Query: 377 RPLPSFCPPRRLDQCPESPLQRCPP----------PAPRPRLRPEPCISLEPRPRPLPRQ 426 PS P P P P+ P L P +L P RP+ + Sbjct: 133 TLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTR 192 Query: 427 LSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHP--EPCPRP------EP 478 S P L P P L P+ P P IP P L P P P RP P Sbjct: 193 SSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTP 252 Query: 479 IPLPAPCPSPEPCRETWRSPSPCW 502 P+ P+ P +PS W Sbjct: 253 TLTPSSTPTLTPSSTPTLTPSSLW 276 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 57.0 bits (136), Expect = 5e-08 Identities = 69/260 (26%), Positives = 93/260 (35%), Gaps = 42/260 (16%) Query: 257 PPPR----RLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTP-PRRSEPIYNSRCPR 311 PPP QL P C+P L + + P P PI P+ Sbjct: 717 PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ 776 Query: 312 RPISSCSQRRGPKCRIEISSPCCPRQVPP----QRCPVEIPPIRRRSQSCGPQPSWGASC 367 P PK + I +P + V P P PP+ + QP++ AS Sbjct: 777 AP---------PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK----QPAFPASY 823 Query: 368 PELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPC----ISLEPRPRPL 423 P P P+P P++ C + PPP+P L P P I+ + P P Sbjct: 824 IPPSPPTPPVPVPPPTLPKQQSFCAK------PPPSP---LSPVPSVVKQIASQFPPPPT 874 Query: 424 PRQLSEPCLYPEPL---PALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP 480 P + L P P P P + P +P +P P P E P P P P Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP 934 Query: 481 LPAPCPSPEPCRETWRSPSP 500 +PAP P P P SP+P Sbjct: 935 VPAPPPPPPPT----ASPTP 950 Score = 45.1 bits (105), Expect = 2e-04 Identities = 35/124 (28%), Positives = 45/124 (36%), Gaps = 13/124 (10%) Query: 400 PPPAPRP-----RLRPEPCISLEPR--PRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRP 452 PPP P P +L+P PC P+ P P ++ + + P P P P+P P P Sbjct: 715 PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP 774 Query: 453 GQC------EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNP 506 Q IP P P P P P ++ PSP P P Sbjct: 775 PQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834 Query: 507 VPYP 510 VP P Sbjct: 835 VPPP 838 Score = 36.2 bits (82), Expect = 0.085 Identities = 43/185 (23%), Positives = 52/185 (28%), Gaps = 69/185 (37%) Query: 378 PLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLS--------- 428 P P P Q P PL PPP P P P P P PLP Q + Sbjct: 611 PQPKIVTPYTASQ-PSPPLPPPPPPPPPPPPPPPP------PPPPLPSQSAPSAGSAAPM 663 Query: 429 ----------------------------------EPCLYPEPLPALRPTPRPVPLPRPGQ 454 +P + P + P P P P P PG Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723 Query: 455 CEIP-EPRPC------------------LQPCEHPEPCPRPEPIPLPAPCPSPEPCRETW 495 +P PC +Q P P P P+PAP P P + Sbjct: 724 AMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLV 783 Query: 496 RSPSP 500 P+P Sbjct: 784 TIPAP 788 Score = 33.5 bits (75), Expect = 0.55 Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 5/55 (9%) Query: 433 YPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487 Y +P L P P+ V Q P P L P P P P P P P P P PS Sbjct: 602 YTSLVPPLSPQPKIVTPYTASQ-----PSPPLPPPPPPPPPPPPPPPPPPPPLPS 651 Score = 31.6 bits (70), Expect = 2.1 Identities = 35/131 (26%), Positives = 42/131 (32%), Gaps = 1/131 (0%) Query: 441 RPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSP 500 RP VP P Q +I P QP P P P P P P P P P P + Sbjct: 600 RPYTSLVP-PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG 658 Query: 501 CWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGPGDVFPERRGQDGH 560 P V Y +S H P P +Q + P V P Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPP 718 Query: 561 GDQGNAFAGVK 571 G+A A +K Sbjct: 719 PTPGSAMAQLK 729 Score = 30.8 bits (68), Expect = 3.6 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Query: 412 PCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRP 462 P SL P P P+ ++ P +P P L P P P P P P P P P Sbjct: 601 PYTSLVPPLSPQPKIVT-PYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650 >gi|239755326 PREDICTED: hypothetical protein [Homo sapiens] Length = 375 Score = 56.6 bits (135), Expect = 6e-08 Identities = 59/221 (26%), Positives = 82/221 (37%), Gaps = 19/221 (8%) Query: 41 CEMQIVDCPASCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAA 99 C Q ++C Q Q S CQS T+ C ++ + CQS T + Sbjct: 18 CSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSCSC 77 Query: 100 SQSQTSSVQSQAPCQSE-VSYVQC--EASQPVQTCFVECAPVCYTETCYVECPVQNYVPC 156 S+TSS S CQS S C + S+ TC + + T C Q+ Sbjct: 78 QSSETSSTCS---CQSSGTSSTSCSWQFSRTSSTCCCQS-----SRTSSTSCSCQSSRTS 129 Query: 157 PAPQPVQMYR-GRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCN-NYTPQFQLRPSY 214 Q R CQ ST C YQ S +S QS T + + Q S Sbjct: 130 STSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSST 189 Query: 215 SSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC 255 SC S TS+S CQ+ G+ + + Q S++ C Sbjct: 190 CSCQSSGTSSTSYS-----CQSSGTSSTCSCQSSGTSSTSC 225 Score = 54.7 bits (130), Expect = 2e-07 Identities = 50/199 (25%), Positives = 76/199 (38%), Gaps = 26/199 (13%) Query: 60 SDQAPCQSQTTQVKCQSKTKQVKGQAQCQSK---TTQVKGQAASQSQTSSVQSQAPCQSE 116 S CQS T C ++ Q CQS +T Q++ S T S QS + Sbjct: 15 SSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTS 74 Query: 117 VSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQG 176 S C++S+ TC + + T + + C + + CQ Sbjct: 75 CS---CQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSRT----SSTSCSCQSSR 127 Query: 177 RFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQT 236 ST C Q S +S +TC+ T R S +SC Y+S + S C CQ+ Sbjct: 128 TSSTSCSCQSSRTS--------STCSCQTS----RTSSTSC--SYQSSRTSSTC--SCQS 171 Query: 237 QGSYGSFTEQHRSRSTSRC 255 G+ + SR++S C Sbjct: 172 SGTSSTSCNWQSSRTSSTC 190 Score = 53.9 bits (128), Expect = 4e-07 Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 14/215 (6%) Query: 51 SCPVQVCQVSDQAPCQ-SQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109 SC Q + S CQ S+T+ C ++ + CQS T S+TSS S Sbjct: 132 SCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCS 191 Query: 110 -QAPCQSEVSYVQCEASQPVQTCFVECAPV------CYTETCYVECPVQNYVPCPAPQPV 162 Q+ S SY C++S TC + + C + C Q+ Sbjct: 192 CQSSGTSSTSY-SCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSW 250 Query: 163 QMYR-GRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQY 221 Q R CQ G ST C Q S +S QS T + R S S+C Q+ Sbjct: 251 QSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTS-STCSCQF 309 Query: 222 RSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRCL 256 SRTS + C CQ+ + + + Q S++ C+ Sbjct: 310 -SRTSSTSC--SCQSSRTSSTCSCQSSGTSSTSCI 341 Score = 48.1 bits (113), Expect = 2e-05 Identities = 56/231 (24%), Positives = 80/231 (34%), Gaps = 23/231 (9%) Query: 51 SCPVQVCQVSDQA-PCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQ-TSSVQ 108 SC Q + S + CQS T C +T + C ++++ + QS TSS Sbjct: 120 SCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRT-SSTSCSYQSSRTSSTCSCQSSGTSSTS 178 Query: 109 SQAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGR 168 S C++S T + C + TC + + C Sbjct: 179 CNWQSSRTSSTCSCQSSGTSSTSY-SCQSSGTSSTCSCQSSGTSSTSCSCQ---SSGTSS 234 Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228 CQ G ST C +Q S +S QS T S +SC Q S + S Sbjct: 235 TCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGT------------SSTSCSCQ--SSGTSS 280 Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCS 279 C CQ+ G+ + SR++S C R SC R CS Sbjct: 281 TC--SCQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCS 329 Score = 41.2 bits (95), Expect = 0.003 Identities = 38/158 (24%), Positives = 55/158 (34%), Gaps = 22/158 (13%) Query: 51 SCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109 SC Q S CQS T+ C ++ + CQS T + S TSS S Sbjct: 224 SCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCS 283 Query: 110 QAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRP 169 + + C++S+ TC + ++ T C Q+ Sbjct: 284 CQSSGTSSTSCSCQSSRTSSTCSCQ-----FSRTSSTSCSCQS-----------SRTSST 327 Query: 170 AVCQPQGRFSTQC---QYQGSYSSCGPQFQ--SRATCN 202 CQ G ST C S +SC +F S +CN Sbjct: 328 CSCQSSGTSSTSCICWSSGTSSTSCSGRFSGTSSTSCN 365 Score = 40.0 bits (92), Expect = 0.006 Identities = 48/170 (28%), Positives = 63/170 (37%), Gaps = 21/170 (12%) Query: 98 AASQSQTSSVQSQAPCQSEV--SYVQCEASQPVQTCFVECAPVCYT----------ETCY 145 A Q + SS S CQS S C++SQ TC + + T TC Sbjct: 7 ACKQHRASS--SSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRTSSTCS 64 Query: 146 VECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYT 205 + + C CQ G ST C +Q S +S QS T + Sbjct: 65 CQSSGTSSTSCSCQ---SSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSC 121 Query: 206 PQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC 255 R S +SC Q SRTS S C CQT + + SR++S C Sbjct: 122 SCQSSRTSSTSCSCQ-SSRTS-STC--SCQTSRTSSTSCSYQSSRTSSTC 167 Score = 38.5 bits (88), Expect = 0.017 Identities = 53/202 (26%), Positives = 73/202 (36%), Gaps = 21/202 (10%) Query: 51 SCPVQVCQVSDQAPCQSQ---TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSV 107 SC Q + S CQS +T CQS CQS T + S TSS Sbjct: 178 SCNWQSSRTSSTCSCQSSGTSSTSYSCQSSG--TSSTCSCQSSGTSSTSCSCQSSGTSST 235 Query: 108 QSQAPCQSE-VSYVQC--EASQPVQTCFVECAPV------CYTETCYVECPVQNYVPCPA 158 S CQS S C ++S+ TC + + C + C Q+ Sbjct: 236 CS---CQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSST 292 Query: 159 PQPVQMYR-GRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSC 217 Q R CQ ST C Q S +S QS T + + S +SC Sbjct: 293 SCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCSCQSSGTSSTSCICWSSGTSSTSC 352 Query: 218 FPQYRSRTSFSPCVPQCQTQGS 239 ++ S TS + C C++ G+ Sbjct: 353 SGRF-SGTSSTSC--NCRSSGT 371 Score = 33.1 bits (74), Expect = 0.72 Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 16/102 (15%) Query: 172 CQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCV 231 CQ G ST C +Q S +S QS T S +SC Q S + S C Sbjct: 42 CQSSGTSSTSCNWQSSRTSSTCSCQSSGT------------SSTSCSCQ--SSETSSTC- 86 Query: 232 PQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPR 273 CQ+ G+ + SR++S C R SC R Sbjct: 87 -SCQSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSCSCQSSR 127 >gi|71274152 hypothetical protein LOC388939 [Homo sapiens] Length = 1288 Score = 56.6 bits (135), Expect = 6e-08 Identities = 72/278 (25%), Positives = 100/278 (35%), Gaps = 44/278 (15%) Query: 239 SYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEP-----CSSSYLPLRPSEGFPN 293 S+ S S+ST P + P P RR S S L L PS+ + Sbjct: 842 SFASLESPESSKSTENS--PKETQEPGPGEAGPTRRTWASPKLRASVSPLDLLPSKSTAS 899 Query: 294 YCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRR 353 P +S P SSC R K +++SSP Q P + + Sbjct: 900 LTKP--------HSTGPGSGRSSCQPR---KPALDLSSPPATSQSPEVKGGTWSQAEKAT 948 Query: 354 SQSCGPQPS--WGASCPELRPH-------VEPR-------PLPSFCPPRRLDQCPESPLQ 397 S P+ + W S P + PR P+ P R P++ + Sbjct: 949 SLYRQPRKAIAWHHSGPPSGQNRTSESSLARPRQSRERSPPVGRKASPTRTHWVPQADKR 1008 Query: 398 RCPPPAPRPRLRPEP-CISLEPRPRPLPRQLSEPCLYPEPLPALRPT-PRPVPLPRPGQC 455 R P+ +P P + P P PR LS P P +P P P P P QC Sbjct: 1009 RRSLPSSYRPAQPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAPAQC 1068 Query: 456 EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRE 493 ++P P P +HPE P P +P+P P P +E Sbjct: 1069 KVPSP-----PTQHPEASP---PFSIPSPSPPMSPSQE 1098 Score = 34.7 bits (78), Expect = 0.25 Identities = 77/307 (25%), Positives = 104/307 (33%), Gaps = 56/307 (18%) Query: 232 PQCQTQGSYGSFTEQHRSRSTSRCLPP------PRRLQLFPRSCSPPRRFEPCSSSYLPL 285 P Q + S S +SR S PP P R P++ +R SSY P Sbjct: 966 PSGQNRTSESSLARPRQSRERS---PPVGRKASPTRTHWVPQA---DKRRRSLPSSYRPA 1019 Query: 286 RPSEG----------FPNYCTPP---RRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSP 332 +PS P +PP RR+ P + + P P S +C++ Sbjct: 1020 QPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAP----AQCKVPSPPT 1075 Query: 333 CCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCP 392 P PP P PP+ + + S + + V FCP Sbjct: 1076 QHPEASPPFSIPSPSPPMSPSQEHKETRDSEDSQA--VIAKVSGNTHSIFCPATSSLFEA 1133 Query: 393 ESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPE-----PLPALRPTP--- 444 + PL P P P L PE L P + S P L + L AL P P Sbjct: 1134 KPPLSTAHPLTP-PSLPPEAGGPL-GNPAECWKNSSGPWLRADSQRRAALCALNPLPFLR 1191 Query: 445 RPVPLPRPGQCEIPEPRPCLQPC-----------EHPEPCPRPEPIPLPAPCPSPEPCRE 493 R +PG P+P P L P E P+ + P +PC SPE Sbjct: 1192 RTASDRQPG--GRPQP-PTLDPTSTSYESQLGQNSSSEESPKKDTEPGSSPC-SPELQGG 1247 Query: 494 TWRSPSP 500 T R+ P Sbjct: 1248 TRRASPP 1254 >gi|117938768 GNAS complex locus alex [Homo sapiens] Length = 626 Score = 56.2 bits (134), Expect = 8e-08 Identities = 81/294 (27%), Positives = 115/294 (39%), Gaps = 66/294 (22%) Query: 263 QLFPRSCSPP--RRFEPCSSSYLPLRP----------------SEGFPNYCTPPRRSEPI 304 +L PRS P +R P ++ LPLR GFP +S Sbjct: 134 ELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELS---HKSTAA 190 Query: 305 YNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWG 364 +SR R + S S P+ R+ S Q P P + + S++ P G Sbjct: 191 ASSRQSRPRVRSASLP--PRTRLPSGS-----QAPSAAHPKRLSDLLLTSRAAAP----G 239 Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424 P+ R + PL S P P+S L P +P P++R +P+ R Sbjct: 240 WRSPDPRSRLAAPPLGSTTLPSTWT-APQSRLTARPSRSPEPQIRESE--QRDPQLRRKQ 296 Query: 425 RQLSEPCL------YP----EPLPALRPTP--------RPVPLPRPGQCE-IPEP---RP 462 ++ EP + YP +PLP +P +P P+ PGQ + IP P +P Sbjct: 297 QRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQP 356 Query: 463 CLQPCEHPEPCPRP-EPIPLPAPCPSPEPCRETWRSPSPCWG----PNPVPYPG 511 L P H +P P P +P+P P P P P R P P G P P+ PG Sbjct: 357 ILTP-GHSQPIPTPGQPLP---PQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPG 406 Score = 50.1 bits (118), Expect = 6e-06 Identities = 79/288 (27%), Positives = 107/288 (37%), Gaps = 50/288 (17%) Query: 232 PQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGF 291 P+ + + + + Q R R S LPP RL P P P S L L Sbjct: 181 PELSHKSTAAASSRQSRPRVRSASLPPRTRL---PSGSQAPSAAHPKRLSDLLLTSRAAA 237 Query: 292 PNYCTPPRRSEPIYNSRCPRRPISSC---SQRRGPKCRIEISSPCCPRQVPPQRCPVEIP 348 P + +P RS R P+ S S P+ R+ P P R + Sbjct: 238 PGWRSPDPRS------RLAAPPLGSTTLPSTWTAPQSRLTARPSRSPE--PQIRESEQRD 289 Query: 349 PIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRL 408 P RR Q +P L P E + P R D P QR P P L Sbjct: 290 PQLRRKQQRWKEP--------LMPRREEK-----YPLRGTDPLPPGQPQRIPLPGQP--L 334 Query: 409 RPEPCISL-EPRPRPLPRQLSEPCLYP----------EPLPALR-PTP----RPVPLPRP 452 +P+P ++ +P+ P P Q +P L P +PLP PTP P P+P P Sbjct: 335 QPQPILTPGQPQKIPTPGQ-HQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTP 393 Query: 453 GQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSP 500 G+ P+P +Q P P P + P SP+ R+T P P Sbjct: 394 GRPLTPQP---IQMPGRPLRLPPPLRLLRPGQPMSPQ-LRQTQGLPLP 437 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 56.2 bits (134), Expect = 8e-08 Identities = 96/352 (27%), Positives = 119/352 (33%), Gaps = 59/352 (16%) Query: 159 PQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCF 218 P+P R RP P+ S+ ++ + S P + RPS Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPS---------------PAARRRPSAGGGL 225 Query: 219 PQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC-----LPPPRRLQ-LFPRSCSPP 272 + SR+ S P S S +R T R P P+ LQ L P +PP Sbjct: 226 QRPASRSLSSSATPLSSPARSGPS------ARGTPRAPAHPSQPKPKGLQALRPPQVTPP 279 Query: 273 RR-----FEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRR----GP 323 R+ P SSS L P+ PP S P P P + SQ P Sbjct: 280 RKDAAPALGPLSSSPLAT------PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 333 Query: 324 KCRIEIS----SPCCPRQVPPQRCP--VEIPPIRRRSQSCGPQPSWGASCPELRPHVEPR 377 + S P P PP + P + +PP++ PS AS P L P P Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA-------PPSPPAS-PPLSPLATPS 385 Query: 378 PLPSFCPPRRLDQCPESPLQRCPPPAP-RPRLRPEPCISLEPRPRPLPRQLSEPCLYPEP 436 P L Q P SP P AP P P S P P P L+ P L P Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP-PSQAPPSLAAPPLQVPP 444 Query: 437 LPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSP 488 P P P P P Q P P LQ + P P P PSP Sbjct: 445 SPPASPPMSPSATP-PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495 Score = 48.1 bits (113), Expect = 2e-05 Identities = 105/373 (28%), Positives = 120/373 (32%), Gaps = 81/373 (21%) Query: 205 TPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQL 264 TP PS S+ P P P Q S GS T Q +T LP P L Sbjct: 297 TPSPSAPPSPSA--PPSLQTLPSPPATPPSQATTSLGSPTLQ----ATHSFLPSPPLSPL 350 Query: 265 F-------PRSCSPPRRFEPCSSSYLPLRP----SEGFPN----------YCTPPRRSEP 303 P PP + P + PL P S PN + PP S P Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP--SPP 408 Query: 304 IYNSRCPRRPISS--CSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQP 361 + + P P +S S P + S P QVPP P PP+ S S P P Sbjct: 409 V---QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS--PPASPPM---SPSATPPP 460 Query: 362 SWGASCPELRPHVEPRPLPSFCPPRRLD---QCPESPLQRCPPPAPRPRLRPEPCISLEP 418 A P P ++ P PP Q SP P AP P L Sbjct: 461 Q--APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518 Query: 419 RPRPLPRQLSEPCLYPEPLPALRPT---PRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPR 475 P P L+ P L P P PT PR P P P + PR L Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP-DTSVSGPRLTL----------- 566 Query: 476 PEPIPLPAPCPSPEPCRETWRSPSPCW-GPNPVPYPGDLGCHESSPHRLDTEAPYCGPSS 534 AP P P P RSPS GP DL H SS E Sbjct: 567 -----ALAPGPPPPPS----RSPSSTLSGP-------DLAGHSSSATSTPEEL-----RG 605 Query: 535 YNQGQESGAGCGP 547 Y+ G E GA P Sbjct: 606 YDSGPEGGAAASP 618 Score = 43.1 bits (100), Expect = 7e-04 Identities = 63/235 (26%), Positives = 83/235 (35%), Gaps = 41/235 (17%) Query: 313 PISSCSQRRGPKCRIEISSPCCPRQVPPQ-----RCPVEIPPIRRRSQSCGP-------Q 360 P+SS + R GP R +P P Q P+ R P PP + + + GP Sbjct: 239 PLSSPA-RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297 Query: 361 PSWGAS-CPELRPHVEPRPLPSFCPPRR----------------LDQCPESPLQRCPPPA 403 PS A P P ++ P P PP + L P SPL PP A Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357 Query: 404 P----RPRLR--PEPCIS--LEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQC 455 P P L+ P P S L P P P+ + ++ P P PV P Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 Query: 456 EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYP 510 P P + P P P+ +P P P P +P P P P+ P Sbjct: 418 SPPVSPSATPPSQAPPSLAAP-PLQVP-PSPPASPPMSPSATPPP-QAPPPLAAP 469 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.319 0.135 0.464 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 34,655,340 Number of Sequences: 37866 Number of extensions: 2832944 Number of successful extensions: 29730 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 316 Number of HSP's successfully gapped in prelim test: 1169 Number of HSP's that attempted gapping in prelim test: 13261 Number of HSP's gapped (non-prelim): 8116 length of query: 579 length of database: 18,247,518 effective HSP length: 108 effective length of query: 471 effective length of database: 14,157,990 effective search space: 6668413290 effective search space used: 6668413290 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.