Guide to the Human Genome
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Search of human proteins with 68563515

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|68563515 keratinocyte proline-rich protein [Homo sapiens]
         (579 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|68563515 keratinocyte proline-rich protein [Homo sapiens]         1276   0.0  
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 83   8e-16
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]               81   2e-15
gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens]    75   2e-13
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    75   2e-13
gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    71   2e-12
gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Hom...    71   2e-12
gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo ...    71   2e-12
gi|67003568 skin-specific protein 32 [Homo sapiens]                    69   1e-11
gi|153792074 proline rich 12 [Homo sapiens]                            67   6e-11
gi|169211819 PREDICTED: keratin associated protein [Homo sapiens]      66   8e-11
gi|239745811 PREDICTED: hypothetical protein XP_002343557 [Homo ...    66   8e-11
gi|83977459 pleckstrin homology-like domain, family A, member 1 ...    64   3e-10
gi|169212026 PREDICTED: keratin associated protein [Homo sapiens]      62   1e-09
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                62   1e-09
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                62   1e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         62   1e-09
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [...    62   2e-09
gi|154800453 tastin isoform 1 [Homo sapiens]                           61   3e-09
gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]                    60   7e-09
gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]            59   2e-08
gi|33186895 selenoprotein V [Homo sapiens]                             59   2e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    58   2e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    58   2e-08
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]            58   3e-08
gi|47132519 Ras association and pleckstrin homology domains 1 is...    57   5e-08
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]            57   6e-08
gi|71274152 hypothetical protein LOC388939 [Homo sapiens]              57   6e-08
gi|117938768 GNAS complex locus alex [Homo sapiens]                    56   8e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    56   8e-08

>gi|68563515 keratinocyte proline-rich protein [Homo sapiens]
          Length = 579

 Score = 1276 bits (3303), Expect = 0.0
 Identities = 579/579 (100%), Positives = 579/579 (100%)

Query: 1   MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS 60
           MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS
Sbjct: 1   MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS 60

Query: 61  DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV 120
           DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV
Sbjct: 61  DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV 120

Query: 121 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST 180
           QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST
Sbjct: 121 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST 180

Query: 181 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY 240
           QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY
Sbjct: 181 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSY 240

Query: 241 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR 300
           GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR
Sbjct: 241 GSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRR 300

Query: 301 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ 360
           SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ
Sbjct: 301 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ 360

Query: 361 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP 420
           PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP
Sbjct: 361 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRP 420

Query: 421 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP 480
           RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP
Sbjct: 421 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP 480

Query: 481 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE 540
           LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE
Sbjct: 481 LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE 540

Query: 541 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF 579
           SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF
Sbjct: 541 SGAGCGPGDVFPERRGQDGHGDQGNAFAGVKGEAKSAYF 579


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 82.8 bits (203), Expect = 8e-16
 Identities = 61/184 (33%), Positives = 68/184 (36%), Gaps = 7/184 (3%)

Query: 331 SPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQ 390
           SP  P   PP   P   PP         P+P     CPEL P   P            + 
Sbjct: 23  SPEPPPPWPPPPPPPAPPPAPPLLSEASPEPI-PEPCPELAPGPCPEATSESATELYTEP 81

Query: 391 CPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLP 450
            PE   +    PAP P   P P  + EP P P P   +E    P P PAL   P P P  
Sbjct: 82  TPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPALESVPEPAPEL 141

Query: 451 RPGQCEIPEPRPCLQPCEH--PEPCPR--PEPIPLPAPC--PSPEPCRETWRSPSPCWGP 504
            P       P P  +P     PE CP   PE  P PAPC    P   RE     SP   P
Sbjct: 142 TPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSP 201

Query: 505 NPVP 508
           +P P
Sbjct: 202 SPSP 205



 Score = 76.3 bits (186), Expect = 7e-14
 Identities = 62/192 (32%), Positives = 69/192 (35%), Gaps = 22/192 (11%)

Query: 358 GPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPC---- 413
           G QP+     P   P   P P P   PP   +  PE      P P P P L P PC    
Sbjct: 17  GEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPE------PIPEPCPELAPGPCPEAT 70

Query: 414 ------ISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRP----GQCEIPEPRPC 463
                 +  EP P P     SEP   P   PA  P   P P P P         P P P 
Sbjct: 71  SESATELYTEPTPEPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPA 130

Query: 464 LQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGP--NPVPYPGDLGCHESSPH 521
           L+    P P   PE  P  AP P+PEP  E      P   P   P P P  L C   +  
Sbjct: 131 LESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRE 190

Query: 522 RLDTEAPYCGPS 533
           R    +P   PS
Sbjct: 191 RGLKTSPSPSPS 202



 Score = 72.8 bits (177), Expect = 8e-13
 Identities = 60/185 (32%), Positives = 71/185 (38%), Gaps = 33/185 (17%)

Query: 371 RPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAP------RPRLRPEPCISLEPRPRPLP 424
           +P   P P P + PP         P    PPPAP       P   PEPC  L P P P  
Sbjct: 19  QPAESPEPPPPWPPP---------PPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEA 69

Query: 425 RQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLP-- 482
              S   LY EP      TP P   P       P P P  +P   P   P PEP P P  
Sbjct: 70  TSESATELYTEP------TPEPATEP----ASEPAPEPATEPAPEPATEPAPEPAPEPAT 119

Query: 483 --APCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQE 540
             AP P+PEP  E+   P+P   P   P        E +P  +   AP   P +  + + 
Sbjct: 120 ESAPEPTPEPALESVPEPAPELTPEVAPELAP----EPTPEPVTELAPEFCPEAAPEFRP 175

Query: 541 SGAGC 545
           S A C
Sbjct: 176 SPAPC 180



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 55/169 (32%), Positives = 63/169 (37%), Gaps = 26/169 (15%)

Query: 384 PPRRLDQCPESPLQRCPPPAPRPRLRPEPC------ISLEPRPRPLPRQLSEPC------ 431
           PP+  +Q  ESP    P P P P   P P        S EP P P P     PC      
Sbjct: 13  PPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATSE 72

Query: 432 ----LYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487
               LY EP P   P   P   P P     P P P  +P   P P P  E  P P P P+
Sbjct: 73  SATELYTEPTP--EPATEPASEPAPEPATEPAPEPATEPAPEPAPEPATESAPEPTPEPA 130

Query: 488 ----PEPCRETWRSPSPCWGPNPVPYP----GDLGCHESSPHRLDTEAP 528
               PEP  E     +P   P P P P        C E++P    + AP
Sbjct: 131 LESVPEPAPELTPEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAP 179


>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
          Length = 411

 Score = 81.3 bits (199), Expect = 2e-15
 Identities = 65/211 (30%), Positives = 81/211 (38%), Gaps = 19/211 (9%)

Query: 341 QRCPVEIPPIRRRSQSCGPQ-PSWGASCPELRPH-VEPRPLPSFCPPRRLDQCPESPLQR 398
           Q+ P  +P  R R     P  P+  AS P+  P  + P   P+ C   +    P    Q+
Sbjct: 27  QQQPQRVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQAWGGPGCRAQK 86

Query: 399 CPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIP 458
             P A            L P P P+P  +  P   P PLP   P P P P   P     P
Sbjct: 87  GIPAA------------LSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAP 134

Query: 459 EPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWR--SPSPCWGPNPVPYPGDLGCH 516
            P P   P + P P   P P P+  P P P P    +   +P P  GPNP P PG +   
Sbjct: 135 IPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISGP 194

Query: 517 ESSPHRLDTEAPYCGPSSYNQGQESGAGCGP 547
              P  +    P  GP S   G  SG   GP
Sbjct: 195 IPGPISVPIPGPIPGPIS---GPISGPNPGP 222



 Score = 63.9 bits (154), Expect = 4e-10
 Identities = 74/250 (29%), Positives = 89/250 (35%), Gaps = 32/250 (12%)

Query: 322 GPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPS 381
           GP CR +   P     + P   P+  P I   +Q  GP P      P   P   P P+P+
Sbjct: 79  GPGCRAQKGIPAA---LSPGPGPIPAP-IPGPAQIPGPLPG-SIPGPIPGPAQIPSPIPA 133

Query: 382 FCP-----PRRLDQCPESPLQR-------CPPPAPRPRLRPEPCISLEPRPRPLPRQLSE 429
             P     P ++      P+          P P   P   P P     P P P+P  +S 
Sbjct: 134 PIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPNPGPIPGPISG 193

Query: 430 PCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPE 489
           P   P  +P   P P P+  P  G    P P P   P   P P P P PI  P P   P 
Sbjct: 194 PIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPG 253

Query: 490 PCRETWRSPSPCWGPNP----VPYPGDL--------GCHESSPHRLDTEAPYCGPSSYNQ 537
           P       P P  GP P    +P PG L             SP  L   AP  GP S   
Sbjct: 254 PIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGPILSPGRMRSPGSLPGLAPILGPGS--- 310

Query: 538 GQESGAGCGP 547
           G  SG+   P
Sbjct: 311 GPGSGSVPAP 320



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 66/227 (29%), Positives = 79/227 (34%), Gaps = 60/227 (26%)

Query: 328 EISSPCCPRQVP-PQRCPVEIP-PIRRRSQS--CGPQPSWGA-SCPELRPHVEPRPLPSF 382
           +I SP  P  +P P   PV+IP P R        GP P  G  S P   P+  P P P+ 
Sbjct: 126 QIPSPI-PAPIPGPISGPVQIPGPFRGPIPGPISGPAPIPGPISGPFSGPNPGPIPGPN- 183

Query: 383 CPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRP 442
                            P P P P   P P     P P P+P  +S P   P P P   P
Sbjct: 184 -----------------PGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGP 226

Query: 443 TPRPVPLPRPGQCEIP--EPRPCLQPCEHPEPCPRPEPI--PLPAPCPSPEPCR------ 492
            P P+  P PG    P   P P L P   P P   P PI  P+P+P   P P R      
Sbjct: 227 IPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPGPGRLQGPGP 286

Query: 493 --------------------------ETWRSPSPCWGPNPVPYPGDL 513
                                      +   P+P  GP  +P P  L
Sbjct: 287 ILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLPAPAPL 333



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 37/127 (29%), Positives = 46/127 (36%), Gaps = 26/127 (20%)

Query: 400 PPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPA--------LRPTPRPVPLPR 451
           P P P P   P P     P P P P     P L P P+P         + P P P  +P 
Sbjct: 218 PNPGPIPGPIPGPISGPNPGPIPGPISGPNPGLIPGPIPGPISGPGPIIGPIPSPAQIPG 277

Query: 452 PGQCEIPEP------------RPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPS 499
           PG+ + P P             P L P   P   P    +P P P P   P      +P+
Sbjct: 278 PGRLQGPGPILSPGRMRSPGSLPGLAPILGPGSGPGSGSVPAPIPGPGSLP------APA 331

Query: 500 PCWGPNP 506
           P W  +P
Sbjct: 332 PLWPQSP 338


>gi|169177031 PREDICTED: similar to hCG30082, partial [Homo sapiens]
          Length = 299

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 58/186 (31%), Positives = 62/186 (33%), Gaps = 14/186 (7%)

Query: 332 PCCPRQVPPQRCPVEIPPI-----RRRSQSCGPQPSWG--ASCPELRPHVEPRPLPSFCP 384
           P     +P   CP   P +      R  Q C P P     AS P  R      P P  C 
Sbjct: 15  PLSMAAIPTYPCPAVSPALLLPRPERVKQCCQPCPRRDLLASWP-CRLFSSETPRPRDCE 73

Query: 385 PRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTP 444
             R   C     + C  P PR    P P     PRPR         C  P P     P P
Sbjct: 74  TPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRPRDCETPRPRDCDTPRP 133

Query: 445 RPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEP----IPLPAPCPSPEPCRETWRSPSP 500
           R    PRP  CE P PR C  P   P  C  P P     P P  C +P P       P  
Sbjct: 134 RDCETPRPRDCETPRPRDCDTP--RPRDCDTPRPRDCDTPRPRDCDTPRPRDCDTPRPRD 191

Query: 501 CWGPNP 506
           C  P P
Sbjct: 192 CDTPRP 197


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
           sapiens]
          Length = 5537

 Score = 74.7 bits (182), Expect = 2e-13
 Identities = 87/300 (29%), Positives = 100/300 (33%), Gaps = 63/300 (21%)

Query: 253 SRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR 312
           SR  PPP    L P     P    P +S   P  P E  P   +PP    P   S  P  
Sbjct: 660 SRLSPPPEESPLSPPPEESPTSPPPEASRLSP--PPEDSPT--SPPPEDSPA--SPPPED 713

Query: 313 PISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELR- 371
            + S      P   +      CPR   P   P      R       P+P      P+   
Sbjct: 714 SLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP------RPEEPHLSPRPEEPHLSPQAEE 767

Query: 372 PHVEPRPL-PSFCP----PRRLDQCPESPLQRCP------PPAPRPRLRP---EPCISLE 417
           PH+ P+P  P  C     P    Q     L   P      P    P L P   EPC+S +
Sbjct: 768 PHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQ 827

Query: 418 PRPRPLPRQLSEPCLYPEP----------LPALRPTPRPVPLPRPGQCEIPEPRPCLQPC 467
           P    L  Q  EPCL P P           P L P P   P   PGQC  PE  P   P 
Sbjct: 828 PEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPP-EEPGQCPAPEELPLFPPP 886

Query: 468 EHP-------EPC----------PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYP 510
             P       EP           P PE +PL    PS EP       P     P+P+P P
Sbjct: 887 GEPSLSPLLGEPALSEPGEPPLSPLPEELPL---SPSGEPSLSPQLMP-----PDPLPPP 938



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 85/292 (29%), Positives = 105/292 (35%), Gaps = 45/292 (15%)

Query: 255 CLPPP-RRLQLFPRSCSPPRRFEPCSSSYLPLRP-SEGFPNYCTPPRRSEPIYNSRCPRR 312
           CL PP   L      C   R    C +    L P SE F NY            S C R 
Sbjct: 302 CLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENY------------SLCHR- 348

Query: 313 PISSCSQRRGPKCRIEIS---SPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPE 369
               C + +G +    ++   +P C R  PP+              +C  QP  G     
Sbjct: 349 ----CHKAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPK-GGHVTS 403

Query: 370 LRPHVEPRPLPSFCPPR-----RLDQCPESPLQR----CPPPAPRPRLRPEPCISLEPRP 420
           ++P  EP PL     P      +L+   E+PL       PPP   P L P P  S    P
Sbjct: 404 MQPK-EPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESP-LSPPPEES-PTSP 460

Query: 421 RPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHP---EPCPRPE 477
            P   +LS P   PE LPA  P P  + L RP +     P P   P   P    P    E
Sbjct: 461 PPEASRLSPP---PEELPA-SPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLE 516

Query: 478 PIPLPAPCPSP-EPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAP 528
             PL  P  SP  P  ET  SP P    +P+  P +       P  L T  P
Sbjct: 517 ESPLSPPEESPPSPALETPLSPPP--EASPLSPPFEESPLSPPPEELPTSPP 566



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 82/295 (27%), Positives = 92/295 (31%), Gaps = 53/295 (17%)

Query: 253 SRCLPPPRRLQLFP-------------RSCSPPRRFEPCSS--SYLPLRPSEGFPNYCTP 297
           SR  PPP  L   P                SPP    P S      P  P E  P   +P
Sbjct: 465 SRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESP--LSP 522

Query: 298 PRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSC 357
           P  S P      P  P    S    P       SP  P   PP+  P   PP   R  S 
Sbjct: 523 PEESPPSPALETPLSPPPEASPLSPPF----EESPLSP---PPEELPTSPPPEASRL-SP 574

Query: 358 GPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRP---RLRPEPCI 414
            P+ S  +  PE  P   P       PP   ++ P SP     P +P P   RL P P  
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPP--FEESPLSPPPEESPLSPPPEASRLSPPPED 632

Query: 415 S-LEPRPRPLPRQLSEPCLYPEPLPA---LRPTPRPVPLPRPGQCEIPEPRP----CLQP 466
           S + P P   P           PLP    L P P   PL  P +     P P       P
Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPP 692

Query: 467 CEHPEPCPRPEPIPLPAP---------------CPSPEPCRETWRSPSPCWGPNP 506
            E     P PE  P   P                P PE  +   RS  P   P P
Sbjct: 693 PEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRP 747



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 73/264 (27%), Positives = 86/264 (32%), Gaps = 75/264 (28%)

Query: 256 LPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPIS 315
           LPPP    L P     P    P +S   P  P E  P        + P+  +    RP+ 
Sbjct: 441 LPPPEESPLSPPPEESPTSPPPEASRLSP--PPEELP--------ASPLPEALHLSRPLE 490

Query: 316 SCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVE 375
                          SP  P   PP+  P+  PP    S    P      S PE  P   
Sbjct: 491 E--------------SPLSP---PPEESPLSPPP---ESSPFSPLEESPLSPPEESP--- 527

Query: 376 PRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP-------RQLS 428
             P P+           E+PL   PPP   P   P     L P P  LP        +LS
Sbjct: 528 --PSPAL----------ETPLS--PPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLS 573

Query: 429 EPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAP---- 484
            P   PE  P + P P   P+  P     PE      P E     P PE  PL  P    
Sbjct: 574 PP---PEESP-MSPPPEESPMSPP-----PEASRLFPPFEESPLSPPPEESPLSPPPEAS 624

Query: 485 --CPSPE------PCRETWRSPSP 500
              P PE      P  E+  SP P
Sbjct: 625 RLSPPPEDSPMSPPPEESPMSPPP 648



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 85/324 (26%), Positives = 108/324 (33%), Gaps = 74/324 (22%)

Query: 257  PPPRRLQLFPRSCSP---PRRFEPCSSSYLP---LRPSEGFPNYCTPPRRSEPIYNSRCP 310
            P P  L L P++  P   P   EPC S       L P    P  C  PR  E   +    
Sbjct: 799  PQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP--CLSPRPEESHLSPELE 856

Query: 311  RRPISSCSQRRGPKCRIEISSPCCPRQVP-PQRCPVEIPPIRRRSQSCGPQPSWG----- 364
            + P+S   ++           P  P Q P P+  P+  PP          +P+       
Sbjct: 857  KPPLSPRPEK----------PPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEP 906

Query: 365  --ASCPE---LRPHVEPRPLPSFCPPRRLDQCPESPL-QRCPPPAPRPRLR--------- 409
              +  PE   L P  EP   P   PP  L   P SP+     PPA  P            
Sbjct: 907  PLSPLPEELPLSPSGEPSLSPQLMPPDPLPP-PLSPIITAAAPPALSPLGELEYPFGAKG 965

Query: 410  ---PEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRP----------VPLPRPGQCE 456
               PE  ++      P+       C  PEP+P +   P P          +  P P QC 
Sbjct: 966  DSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCS 1025

Query: 457  IPEPRPCLQPCEHPEPCPRPEPIPLPAPCP-SP--------------EPCRETWRSPS-P 500
             P  +  L P   P     P  +PL  P P SP              E   E    P  P
Sbjct: 1026 -PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECP 1084

Query: 501  CWGP---NPVPYP-GDLGCHESSP 520
               P   +P+P P GDL C   SP
Sbjct: 1085 ALEPSATSPLPSPMGDLSCPAPSP 1108



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 37/125 (29%), Positives = 47/125 (37%), Gaps = 16/125 (12%)

Query: 401  PPAPRPRLRPE---PCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEI 457
            P +P   LRP+   P  +L P P   P  +  P  Y +P      TPRP P P    C +
Sbjct: 2340 PQSPGLGLRPQEPPPAQALAPSPPSHP-DIFRPGSYTDPYAQPPLTPRPQPPPPESCCAL 2398

Query: 458  PEPRPCLQPCEHPEPCPR----------PEPIPLPAPCPSPEPCRETWRSPSPCWGPNPV 507
            P       P       P+          P P+   A CPSP   R  ++SP P   P   
Sbjct: 2399 PPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPR--FQSPDPYSRPPSR 2456

Query: 508  PYPGD 512
            P   D
Sbjct: 2457 PQSRD 2461



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 44/152 (28%), Positives = 54/152 (35%), Gaps = 34/152 (22%)

Query: 335  PRQVPPQRCPVEIPP----IRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFC--PPRRL 388
            P++ PP +     PP    I R      P        P L P  +P P  S C  PPR L
Sbjct: 2349 PQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQ-----PPLTPRPQPPPPESCCALPPRSL 2403

Query: 389  DQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPV- 447
               P  P  R P     P+ +      L PRP      LS     P P+     +P P  
Sbjct: 2404 ---PSDPFSRVPAS---PQSQSSSQSPLTPRP------LSAEAFCPSPVTPRFQSPDPYS 2451

Query: 448  -PLPRPGQCEIPEPRPCLQPCEHPEPCPRPEP 478
             P  R      P+ R    P   P   PRP+P
Sbjct: 2452 RPPSR------PQSRDPFAPLHKP---PRPQP 2474



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 28/85 (32%), Positives = 32/85 (37%), Gaps = 18/85 (21%)

Query: 392  PESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPR 451
            PE P    PPP+P   L P P     P   PL    +EP   P         P P PLP 
Sbjct: 4911 PEEP---SPPPSP---LAPSPA---SPPTEPLVELPTEPLAEP---------PVPSPLPL 4952

Query: 452  PGQCEIPEPRPCLQPCEHPEPCPRP 476
                E   P+P  +P E  E    P
Sbjct: 4953 ASSPESARPKPRARPPEEGEDSRPP 4977



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 30/86 (34%), Positives = 37/86 (43%), Gaps = 15/86 (17%)

Query: 425  RQLSEPCLYPEPLPALRPTPRPVPL-PRPGQCEIPEPRPCLQ-PCEHPEPCPRPEPIPLP 482
            RQLS P       P   P+P P PL P P     P   P ++ P E     P P P+PL 
Sbjct: 4904 RQLSAP-------PPEEPSPPPSPLAPSPAS---PPTEPLVELPTEPLAEPPVPSPLPLA 4953

Query: 483  APCPSPEPCRETWRSPSPCWGPNPVP 508
            +   SPE  R   R+  P  G +  P
Sbjct: 4954 S---SPESARPKPRARPPEEGEDSRP 4976



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 5/65 (7%)

Query: 368  PELRPHVEPRPL---PSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424
            P   P   P PL   P+  P   L + P  PL   P P+P P L   P  S  P+PR  P
Sbjct: 4910 PPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLP-LASSP-ESARPKPRARP 4967

Query: 425  RQLSE 429
             +  E
Sbjct: 4968 PEEGE 4972



 Score = 30.4 bits (67), Expect = 4.7
 Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 2/59 (3%)

Query: 422  PLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCE--IPEPRPCLQPCEHPEPCPRPEP 478
            P P + S P     P PA  PT   V LP     E  +P P P     E   P PR  P
Sbjct: 4909 PPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARP 4967


>gi|169790903 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 14/126 (11%)

Query: 376 PRPLP---SFCPP-----RRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQL 427
           PRP+    +  PP       LD   E+P Q    P P P   P P   L P P P P  +
Sbjct: 95  PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 154

Query: 428 SEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487
           + P   P  +  L P P P P P P       P P   P   P P P P P P PAP  +
Sbjct: 155 AAPVAAPVAVAVLAPAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAPAPAPAPDAA 208

Query: 488 PEPCRE 493
           P+   E
Sbjct: 209 PQESAE 214



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 9/109 (8%)

Query: 403 APRPRLRP--EPCISLEPRPRPLPR-QLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459
           A  P L P  E    LE  P  LP   +  P   P P+P L P P P P P       P 
Sbjct: 103 AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPV 162

Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVP 508
               L P   P P P P P P+ AP P+P P      +P+P   P P P
Sbjct: 163 AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP------APAPAPAPAPAP 205



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%)

Query: 416 LEPRPRPLPRQLSEPCLYP--EPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPC 473
           L PRP  +   +S P L P  E L  L   P  +P        +P P P   P   P   
Sbjct: 93  LAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLA 144

Query: 474 PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPS 533
           P P P P P   P   P      +P+P   P P P P  +     +P      AP   P+
Sbjct: 145 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 204

Query: 534 SYNQGQESG-AGCGPGDVFPERRGQDGHGDQGNAFAGVKG 572
                QES   G   G     +RGQ+   DQ    +G+ G
Sbjct: 205 PDAAPQESAEQGANQG-----QRGQEPLADQ--LHSGISG 237



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%)

Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424
           AS P   P + P P P+  P       P +     P PAP P   P P     P P P P
Sbjct: 134 ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP 193

Query: 425 RQLSEPCLYPEPLPALRPTPRPVP 448
                    P P PA  P P   P
Sbjct: 194 A--------PAPAPAPAPAPDAAP 209


>gi|169790899 cyclin-dependent kinase inhibitor 1C isoform b [Homo
           sapiens]
          Length = 305

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 14/126 (11%)

Query: 376 PRPLP---SFCPP-----RRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQL 427
           PRP+    +  PP       LD   E+P Q    P P P   P P   L P P P P  +
Sbjct: 95  PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 154

Query: 428 SEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487
           + P   P  +  L P P P P P P       P P   P   P P P P P P PAP  +
Sbjct: 155 AAPVAAPVAVAVLAPAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAPAPAPAPDAA 208

Query: 488 PEPCRE 493
           P+   E
Sbjct: 209 PQESAE 214



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 9/109 (8%)

Query: 403 APRPRLRP--EPCISLEPRPRPLPR-QLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459
           A  P L P  E    LE  P  LP   +  P   P P+P L P P P P P       P 
Sbjct: 103 AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPV 162

Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVP 508
               L P   P P P P P P+ AP P+P P      +P+P   P P P
Sbjct: 163 AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP------APAPAPAPAPAP 205



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%)

Query: 416 LEPRPRPLPRQLSEPCLYP--EPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPC 473
           L PRP  +   +S P L P  E L  L   P  +P        +P P P   P   P   
Sbjct: 93  LAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLA 144

Query: 474 PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPS 533
           P P P P P   P   P      +P+P   P P P P  +     +P      AP   P+
Sbjct: 145 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 204

Query: 534 SYNQGQESG-AGCGPGDVFPERRGQDGHGDQGNAFAGVKG 572
                QES   G   G     +RGQ+   DQ    +G+ G
Sbjct: 205 PDAAPQESAEQGANQG-----QRGQEPLADQ--LHSGISG 237



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%)

Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424
           AS P   P + P P P+  P       P +     P PAP P   P P     P P P P
Sbjct: 134 ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP 193

Query: 425 RQLSEPCLYPEPLPALRPTPRPVP 448
                    P P PA  P P   P
Sbjct: 194 A--------PAPAPAPAPAPDAAP 209


>gi|4557441 cyclin-dependent kinase inhibitor 1C isoform a [Homo
           sapiens]
          Length = 316

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 43/126 (34%), Positives = 51/126 (40%), Gaps = 14/126 (11%)

Query: 376 PRPLP---SFCPP-----RRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQL 427
           PRP+    +  PP       LD   E+P Q    P P P   P P   L P P P P  +
Sbjct: 106 PRPVAVAVAVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPV 165

Query: 428 SEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487
           + P   P  +  L P P P P P P       P P   P   P P P P P P PAP  +
Sbjct: 166 AAPVAAPVAVAVLAPAPAPAPAPAPA------PAPVAAPAPAPAPAPAPAPAPAPAPDAA 219

Query: 488 PEPCRE 493
           P+   E
Sbjct: 220 PQESAE 225



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 9/109 (8%)

Query: 403 APRPRLRP--EPCISLEPRPRPLPR-QLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459
           A  P L P  E    LE  P  LP   +  P   P P+P L P P P P P       P 
Sbjct: 114 AVSPPLEPAAESLDGLEEAPEQLPSVPVPAPASTPPPVPVLAPAPAPAPAPVAAPVAAPV 173

Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVP 508
               L P   P P P P P P+ AP P+P P      +P+P   P P P
Sbjct: 174 AVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP------APAPAPAPAPAP 216



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 47/160 (29%), Positives = 60/160 (37%), Gaps = 18/160 (11%)

Query: 416 LEPRPRPLPRQLSEPCLYP--EPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPC 473
           L PRP  +   +S P L P  E L  L   P  +P        +P P P   P   P   
Sbjct: 104 LAPRPVAVAVAVSPP-LEPAAESLDGLEEAPEQLP-------SVPVPAPASTPPPVPVLA 155

Query: 474 PRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPS 533
           P P P P P   P   P      +P+P   P P P P  +     +P      AP   P+
Sbjct: 156 PAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAPAPAPAPAPAPA 215

Query: 534 SYNQGQESG-AGCGPGDVFPERRGQDGHGDQGNAFAGVKG 572
                QES   G   G     +RGQ+   DQ    +G+ G
Sbjct: 216 PDAAPQESAEQGANQG-----QRGQEPLADQ--LHSGISG 248



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 27/84 (32%), Positives = 30/84 (35%), Gaps = 8/84 (9%)

Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424
           AS P   P + P P P+  P       P +     P PAP P   P P     P P P P
Sbjct: 145 ASTPPPVPVLAPAPAPAPAPVAAPVAAPVAVAVLAPAPAPAPAPAPAPAPVAAPAPAPAP 204

Query: 425 RQLSEPCLYPEPLPALRPTPRPVP 448
                    P P PA  P P   P
Sbjct: 205 A--------PAPAPAPAPAPDAAP 220


>gi|67003568 skin-specific protein 32 [Homo sapiens]
          Length = 250

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 70/222 (31%), Positives = 91/222 (40%), Gaps = 53/222 (23%)

Query: 1   MCDQQQIQCRLPLQQCCVKGPSFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVS 60
           MCDQQ+ Q + P    CVKG    + Q     S            V CP  C  Q   V+
Sbjct: 1   MCDQQK-QPQFP--PSCVKGSGLGAGQGSNGAS------------VKCPVPCQTQTVCVT 45

Query: 61  DQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYV 120
             APC +QT           VK Q  CQ   TQ   +  +  Q + V+   PCQ+   YV
Sbjct: 46  GPAPCPTQT----------YVKYQVPCQ---TQTYVKCPAPCQRTYVKYPTPCQT---YV 89

Query: 121 QCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFST 180
           +C A  P QT +V+C   C           Q YV CPAP  +  Y   PA CQ Q     
Sbjct: 90  KCPA--PCQTTYVKCPTPC-----------QTYVKCPAPCQM-TYIKSPAPCQTQ----- 130

Query: 181 QCQYQGSYSSCGPQFQSRATCNNYTPQFQLR-PSYSSCFPQY 221
            C  QG+ S C   +  +A  +  T Q+ +  P  + C   Y
Sbjct: 131 TCYVQGA-SPC-QSYYVQAPASGSTSQYCVTDPCSAPCSTSY 170



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 70/275 (25%), Positives = 86/275 (31%), Gaps = 93/275 (33%)

Query: 84  QAQCQSKTTQVKGQAASQSQTS---SVQSQAPCQSEVSYVQCEASQPVQTCFVECAPVCY 140
           Q Q Q   + VKG      Q S   SV+   PCQ++   V   A  P QT +V+    C 
Sbjct: 5   QKQPQFPPSCVKGSGLGAGQGSNGASVKCPVPCQTQTVCVTGPAPCPTQT-YVKYQVPCQ 63

Query: 141 TETCYVECPVQNYVPCPA-----PQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQF 195
           T+T YV+CP     PC       P P Q Y   PA CQ             +Y  C    
Sbjct: 64  TQT-YVKCPA----PCQRTYVKYPTPCQTYVKCPAPCQT------------TYVKCPTPC 106

Query: 196 QSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQ-CQTQGSYGSFTEQHRSRSTSR 254
           Q+   C             + C   Y    S +PC  Q C  QG+               
Sbjct: 107 QTYVKCP------------APCQMTYIK--SPAPCQTQTCYVQGA--------------- 137

Query: 255 CLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRC---PR 311
                                 PC S Y+    S     YC     S P   S C   PR
Sbjct: 138 ---------------------SPCQSYYVQAPASGSTSQYCVTDPCSAPCSTSYCCLAPR 176

Query: 312 ------------RPISSCSQRRGPKCRIEISSPCC 334
                       RP  +C+      C    SS CC
Sbjct: 177 TFGVSPLRRWIQRP-QNCNTGSSGCCENSGSSGCC 210



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)

Query: 422 PLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQP-CEHPEPCPRPEPIP 480
           P+P Q    C+   P P    T     +P   Q  +  P PC +   ++P PC     + 
Sbjct: 34  PVPCQTQTVCV-TGPAPCPTQTYVKYQVPCQTQTYVKCPAPCQRTYVKYPTPCQTY--VK 90

Query: 481 LPAPCPS-----PEPCRETWRSPSPC 501
            PAPC +     P PC+   + P+PC
Sbjct: 91  CPAPCQTTYVKCPTPCQTYVKCPAPC 116


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 66.6 bits (161), Expect = 6e-11
 Identities = 54/174 (31%), Positives = 69/174 (39%), Gaps = 27/174 (15%)

Query: 389  DQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVP 448
            D  P +P    P P P P L   P  +    P P   +   P   P P PA  P P+P P
Sbjct: 1420 DGPPLAPAAAVPGPPPLPGL---PSANSNGTPEPPLLEEKPP---PTPPPAPTPQPQPPP 1473

Query: 449  LPRPGQCEIPEPRPCLQPCEH---PEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPN 505
             P P Q  +P P P + P      P P P P P  +P+P P P P      + +P   P 
Sbjct: 1474 PPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPSPPPPPPP------AAAPLAAPP 1527

Query: 506  PVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGPGDVFPERRGQDG 559
              P         ++P   D E P   P    + QE+ A CG  D   E  G+ G
Sbjct: 1528 EEP---------AAPSPEDPELPDTRPLHLAKKQETAAVCGETD---EEAGESG 1569



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 50/171 (29%), Positives = 58/171 (33%), Gaps = 12/171 (7%)

Query: 329  ISSPCCPRQVPPQRCPVEI-----PPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFC 383
            ISS       PP   P +      PP+   +   GP P  G          EP  L    
Sbjct: 1398 ISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKP 1457

Query: 384  PPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPT 443
            PP         P    PPP P+P L   P     P   P P     P L P P PA+ P+
Sbjct: 1458 PPTPPPAPTPQPQPPPPPPPPQPALPSPP-----PLVAPTPSSPPPPPLPPPPPPAM-PS 1511

Query: 444  PRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRET 494
            P P P P       P   P     E PE  P   P+ L     +   C ET
Sbjct: 1512 PPPPPPPAAAPLAAPPEEPAAPSPEDPE-LPDTRPLHLAKKQETAAVCGET 1561



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 68/262 (25%), Positives = 87/262 (33%), Gaps = 52/262 (19%)

Query: 310  PRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPE 369
            P  P +  +Q       +E   P  P  +PP   P  +P +   + S  P  S       
Sbjct: 766  PPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPP-PQLLPSVLSHAPSPSPSAS-KVGVHL 823

Query: 370  LRPHVE---PRPLPSFCPPRRLDQCPESPLQR--------CPPPAPRPRLRPEPCISLEP 418
            L P      P+P P   PP      P  PLQ           P AP PRLRPE   SL+P
Sbjct: 824  LEPATRDGAPQPPPPPPPPP-----PPMPLQLEAHLRSHGLEPAAPSPRLRPEE--SLDP 876

Query: 419  RPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPR------PCLQPCEHPEP 472
                       P    E L AL P P     P PG   +  P               P+ 
Sbjct: 877  -----------PGAMQELLGALEPLP-----PAPGDTGVGPPNSEGKDPAGAYRSPSPQG 920

Query: 473  CPRPEPIPLPAPCPSPEPCRETWRSPSP----CWGPNPVPYPGDLGCHESSPHRLDTEAP 528
               P  +PL + C      ++  RS  P     +G       G  G  E          P
Sbjct: 921  TKAPRFVPLTSICFPDSLLQDEERSFFPTMEEMFGGGAADDYGKAGPPEDEGDPKAGAGP 980

Query: 529  YCGPSSYN------QGQESGAG 544
              GP +Y+       G+ SGAG
Sbjct: 981  PPGPPAYDPYGPYCPGRASGAG 1002



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 40/147 (27%), Positives = 55/147 (37%), Gaps = 24/147 (16%)

Query: 334  CPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPE 393
            C R+ P  R PV   P+RR  Q+  P  + G+S P   P   P P     PP+   + PE
Sbjct: 1662 CARK-PWHRPPV---PVRRSGQAKNPVSAGGSSAP---PPKAPAP-----PPK--PETPE 1707

Query: 394  SPLQRCPPPAPRPRLRPEPCISLEP---RPRPLPRQLSEPCLYPEPLPALRPT------- 443
                  PP        PEP    +P   RP    ++  +      PL   R T       
Sbjct: 1708 KTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEKEKVTRGERPLRGERATSGRQTRP 1767

Query: 444  PRPVPLPRPGQCEIPEPRPCLQPCEHP 470
             R +   +P    +P+ RP     E P
Sbjct: 1768 ERSLATGQPATSRLPKARPTKVKAEPP 1794



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 40/163 (24%), Positives = 56/163 (34%), Gaps = 16/163 (9%)

Query: 141 TETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRAT 200
           + T + E  + +     AP P+Q Y          G F T   + GS           + 
Sbjct: 35  SRTSHPETDILHRQAYAAPHPLQSYATNHHPAGLSGLFDTGLHHAGSAGPDASVMNLISA 94

Query: 201 CNNYTPQFQLRPSYSSCFPQYRSRT-------------SFSPCVPQCQTQGSYGSFTE-Q 246
             +  PQ    PS SS   Q+RS +               S  +P   T  S  + +  Q
Sbjct: 95  LESRGPQ--PGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQ 152

Query: 247 HRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSE 289
           H +   SR  P P  L L     SPP          L L+PS+
Sbjct: 153 HPASFGSRPFPVPSSLSLQDPPFSPPANGLLSPHDVLHLKPSQ 195


>gi|169211819 PREDICTED: keratin associated protein [Homo sapiens]
          Length = 517

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 136/562 (24%), Positives = 182/562 (32%), Gaps = 126/562 (22%)

Query: 24  CSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVSDQAPCQSQTTQ-VKCQSKTKQVK 82
           CSS+  F+   V   + C  ++     SC   +C  S    CQSQT Q V CQ       
Sbjct: 5   CSSRKCFS---VPATSLCSTEV-----SCGGPICLPSS---CQSQTWQLVTCQDSCGSSS 53

Query: 83  GQAQCQSKTTQVKGQA---------ASQSQTSSVQSQAPCQSEVSYVQCEASQPVQTCFV 133
              QC+  +  V   A            S + S   Q  C    +   CE S  V  C+ 
Sbjct: 54  CGPQCRQPSCPVSSCAQPLCCDPVICEPSCSVSSGCQPVCCEATT---CEPSCSVSNCY- 109

Query: 134 ECAPVCYTET-CYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCG 192
              PVC+  T C   C V N                   CQP    +T C+   S SSC 
Sbjct: 110 --QPVCFEATICEPSCSVSN------------------CCQPVCFEATVCEPSCSVSSC- 148

Query: 193 PQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRST 252
               ++  C               C P          C P C           +  S   
Sbjct: 149 ----AQPVC---------------CEPAI--------CEPSCSVSSCCQPVGSEATSCQP 181

Query: 253 SRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR 312
             C+P   +  L   SC  P   EP   S +   PS   P  C  P   +P+    CP  
Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVC-EPSCCQPV----CPTP 236

Query: 313 PISSCSQRRGPKCRIEISSPCCPRQ--VPPQRC------PVEIPPIRRRSQSCGPQPSWG 364
             S  S  +   C      P C       P  C      PV + P+     SC P PS  
Sbjct: 237 TCSVTSSCQAVCCDPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEP-PSVP 295

Query: 365 ASCPELRPHVEP--RPL---PSFCPPRRLDQCPESP----LQRCPPPAPRPRLRPEP--- 412
           ++C E    V    +P+   PS C P      P  P    ++RCP   P P   P     
Sbjct: 296 STCQEPSCCVSSICQPICSEPSPCSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCR 355

Query: 413 -------------CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459
                        C    PR   +P     PC       + RP  RP+  P      +  
Sbjct: 356 PLSCSPGSSASAICRPTCPRTFYIPSSSKRPC---SATISYRPVSRPICRPICSGL-LTY 411

Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAP-CPSPEPCRETWRSPS-----PCWGPNPVPYPGDL 513
            +P +    +   C RP    L  P C +   CR  +  PS      C           L
Sbjct: 412 RQPYMTSISYRPACYRPCYSILRRPACVTSYSCRPVYFRPSCTESDSCKRDCKKSTSSQL 471

Query: 514 GCHESSPHRLDT--EAPYCGPS 533
            C +++P ++D   EAP C P+
Sbjct: 472 DCVDTTPCKVDVSEEAP-CQPT 492



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 95/396 (23%), Positives = 119/396 (30%), Gaps = 73/396 (18%)

Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228
           P+ CQ Q      CQ     SSCGPQ      C   +           C P         
Sbjct: 32  PSSCQSQTWQLVTCQDSCGSSSCGPQ------CRQPSCPVSSCAQPLCCDPVI------- 78

Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPS 288
            C P C                 +S C P          SCS    ++P         PS
Sbjct: 79  -CEPSCSV---------------SSGCQPVCCEATTCEPSCSVSNCYQPVCFEATICEPS 122

Query: 289 EGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKC--------RIEISSPCCPRQVPP 340
               N C P      +    C    +SSC+Q   P C           +SS C P     
Sbjct: 123 CSVSNCCQPVCFEATVCEPSCS---VSSCAQ---PVCCEPAICEPSCSVSSCCQPVGSEA 176

Query: 341 QRC------PVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPES 394
             C      P    P+  +S  C P     + C  +        LPS C P     C  S
Sbjct: 177 TSCQPVLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCT------LPSSCQPV---VCEPS 227

Query: 395 PLQRCPPPAPRPRLR-PEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPG 453
               C P  P P       C ++   P P     SE  +  +P   +     PV L RP 
Sbjct: 228 C---CQPVCPTPTCSVTSSCQAVCCDPSPCEPSCSESSIC-QPATCVALVCEPVCL-RPV 282

Query: 454 QC--EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511
            C     EP      C+ P  C      P+   C  P PC       SPC    P  Y  
Sbjct: 283 CCVQSSCEPPSVPSTCQEPSCCVSSICQPI---CSEPSPCSPAVCVSSPC---QPTCYVV 336

Query: 512 DLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGP 547
              C    P  +   +  C P S + G  + A C P
Sbjct: 337 KR-CPSVCPEPVSCPSTSCRPLSCSPGSSASAICRP 371



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 90/379 (23%), Positives = 122/379 (32%), Gaps = 67/379 (17%)

Query: 5   QQIQCRLPLQQCCVKGPSFCSSQS--PFAQSQVVVQAPCEMQIVDCP-----ASCPVQVC 57
           Q + C+    Q  V  PS CS+    P +   VV +  C   +   P     +SC    C
Sbjct: 190 QPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVCEPSCCQPVCPTPTCSVTSSCQAVCC 249

Query: 58  QVSDQAPCQSQTTQVK-CQSKT-KQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQS 115
              D +PC+   ++   CQ  T   +  +  C      V+      S  S+ Q  + C S
Sbjct: 250 ---DPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVS 306

Query: 116 EVSYVQCEASQPVQTCFVECAP-VCYTETCYVECPVQNYVP--CPAPQPVQMYRGRPAVC 172
            +    C    P       C+P VC +  C   C V    P  CP P        RP  C
Sbjct: 307 SICQPICSEPSP-------CSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCRPLSC 359

Query: 173 QPQGRFSTQCQYQGSYSSCGPQFQSRATCNN--YTPQFQLRPSYSSCFPQYRSRTSFSPC 230
            P    S  C               R TC    Y P    RP   S    YR   S   C
Sbjct: 360 SPGSSASAIC---------------RPTCPRTFYIPSSSKRP--CSATISYRP-VSRPIC 401

Query: 231 VPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEG 290
            P C    +Y       +   TS    P        R C    R   C +SY        
Sbjct: 402 RPICSGLLTY------RQPYMTSISYRP-----ACYRPCYSILRRPACVTSY------SC 444

Query: 291 FPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEIS--SPCCPRQVPPQRCPVEIP 348
            P Y  P           C +   S         C++++S  +PC P +  P      I 
Sbjct: 445 RPVYFRPSCTESDSCKRDCKKSTSSQLDCVDTTPCKVDVSEEAPCQPTEAKP------IS 498

Query: 349 PIRRRSQSCGPQPSWGASC 367
           P  R + +  P  S  A+C
Sbjct: 499 PTTREAAAAQPAASKPANC 517


>gi|239745811 PREDICTED: hypothetical protein XP_002343557 [Homo
           sapiens]
          Length = 517

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 136/562 (24%), Positives = 182/562 (32%), Gaps = 126/562 (22%)

Query: 24  CSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVSDQAPCQSQTTQ-VKCQSKTKQVK 82
           CSS+  F+   V   + C  ++     SC   +C  S    CQSQT Q V CQ       
Sbjct: 5   CSSRKCFS---VPATSLCSTEV-----SCGGPICLPSS---CQSQTWQLVTCQDSCGSSS 53

Query: 83  GQAQCQSKTTQVKGQA---------ASQSQTSSVQSQAPCQSEVSYVQCEASQPVQTCFV 133
              QC+  +  V   A            S + S   Q  C    +   CE S  V  C+ 
Sbjct: 54  CGPQCRQPSCPVSSCAQPLCCDPVICEPSCSVSSGCQPVCCEATT---CEPSCSVSNCY- 109

Query: 134 ECAPVCYTET-CYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCG 192
              PVC+  T C   C V N                   CQP    +T C+   S SSC 
Sbjct: 110 --QPVCFEATICEPSCSVSN------------------CCQPVCFEATVCEPSCSVSSC- 148

Query: 193 PQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRST 252
               ++  C               C P          C P C           +  S   
Sbjct: 149 ----AQPVC---------------CEPAI--------CEPSCSVSSCCQPVGSEATSCQP 181

Query: 253 SRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR 312
             C+P   +  L   SC  P   EP   S +   PS   P  C  P   +P+    CP  
Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVC-EPSCCQPV----CPTP 236

Query: 313 PISSCSQRRGPKCRIEISSPCCPRQ--VPPQRC------PVEIPPIRRRSQSCGPQPSWG 364
             S  S  +   C      P C       P  C      PV + P+     SC P PS  
Sbjct: 237 TCSVTSSCQAVCCDPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEP-PSVP 295

Query: 365 ASCPELRPHVEP--RPL---PSFCPPRRLDQCPESP----LQRCPPPAPRPRLRPEP--- 412
           ++C E    V    +P+   PS C P      P  P    ++RCP   P P   P     
Sbjct: 296 STCQEPSCCVSSICQPICSEPSPCSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCR 355

Query: 413 -------------CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPE 459
                        C    PR   +P     PC       + RP  RP+  P      +  
Sbjct: 356 PLSCSPGSSASAICRPTCPRTFYIPSSSKRPC---SATISYRPVSRPICRPICSGL-LTY 411

Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAP-CPSPEPCRETWRSPS-----PCWGPNPVPYPGDL 513
            +P +    +   C RP    L  P C +   CR  +  PS      C           L
Sbjct: 412 RQPYMTSISYRPACYRPCYSILRRPACVTSYSCRPVYFRPSCTESDSCKRDCKKSTSSQL 471

Query: 514 GCHESSPHRLDT--EAPYCGPS 533
            C +++P ++D   EAP C P+
Sbjct: 472 DCVDTTPCKVDVSEEAP-CQPT 492



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 95/396 (23%), Positives = 119/396 (30%), Gaps = 73/396 (18%)

Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228
           P+ CQ Q      CQ     SSCGPQ      C   +           C P         
Sbjct: 32  PSSCQSQTWQLVTCQDSCGSSSCGPQ------CRQPSCPVSSCAQPLCCDPVI------- 78

Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPS 288
            C P C                 +S C P          SCS    ++P         PS
Sbjct: 79  -CEPSCSV---------------SSGCQPVCCEATTCEPSCSVSNCYQPVCFEATICEPS 122

Query: 289 EGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKC--------RIEISSPCCPRQVPP 340
               N C P      +    C    +SSC+Q   P C           +SS C P     
Sbjct: 123 CSVSNCCQPVCFEATVCEPSCS---VSSCAQ---PVCCEPAICEPSCSVSSCCQPVGSEA 176

Query: 341 QRC------PVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPES 394
             C      P    P+  +S  C P     + C  +        LPS C P     C  S
Sbjct: 177 TSCQPVLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCT------LPSSCQPV---VCEPS 227

Query: 395 PLQRCPPPAPRPRLR-PEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPG 453
               C P  P P       C ++   P P     SE  +  +P   +     PV L RP 
Sbjct: 228 C---CQPVCPTPTCSVTSSCQAVCCDPSPCEPSCSESSIC-QPATCVALVCEPVCL-RPV 282

Query: 454 QC--EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511
            C     EP      C+ P  C      P+   C  P PC       SPC    P  Y  
Sbjct: 283 CCVQSSCEPPSVPSTCQEPSCCVSSICQPI---CSEPSPCSPAVCVSSPC---QPTCYVV 336

Query: 512 DLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGP 547
              C    P  +   +  C P S + G  + A C P
Sbjct: 337 KR-CPSVCPEPVSCPSTSCRPLSCSPGSSASAICRP 371



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 90/379 (23%), Positives = 122/379 (32%), Gaps = 67/379 (17%)

Query: 5   QQIQCRLPLQQCCVKGPSFCSSQS--PFAQSQVVVQAPCEMQIVDCP-----ASCPVQVC 57
           Q + C+    Q  V  PS CS+    P +   VV +  C   +   P     +SC    C
Sbjct: 190 QPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVCEPSCCQPVCPTPTCSVTSSCQAVCC 249

Query: 58  QVSDQAPCQSQTTQVK-CQSKT-KQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQS 115
              D +PC+   ++   CQ  T   +  +  C      V+      S  S+ Q  + C S
Sbjct: 250 ---DPSPCEPSCSESSICQPATCVALVCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVS 306

Query: 116 EVSYVQCEASQPVQTCFVECAP-VCYTETCYVECPVQNYVP--CPAPQPVQMYRGRPAVC 172
            +    C    P       C+P VC +  C   C V    P  CP P        RP  C
Sbjct: 307 SICQPICSEPSP-------CSPAVCVSSPCQPTCYVVKRCPSVCPEPVSCPSTSCRPLSC 359

Query: 173 QPQGRFSTQCQYQGSYSSCGPQFQSRATCNN--YTPQFQLRPSYSSCFPQYRSRTSFSPC 230
            P    S  C               R TC    Y P    RP   S    YR   S   C
Sbjct: 360 SPGSSASAIC---------------RPTCPRTFYIPSSSKRP--CSATISYRP-VSRPIC 401

Query: 231 VPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEG 290
            P C    +Y       +   TS    P        R C    R   C +SY        
Sbjct: 402 RPICSGLLTY------RQPYMTSISYRP-----ACYRPCYSILRRPACVTSY------SC 444

Query: 291 FPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEIS--SPCCPRQVPPQRCPVEIP 348
            P Y  P           C +   S         C++++S  +PC P +  P      I 
Sbjct: 445 RPVYFRPSCTESDSCKRDCKKSTSSQLDCVDTTPCKVDVSEEAPCQPTEAKP------IS 498

Query: 349 PIRRRSQSCGPQPSWGASC 367
           P  R + +  P  S  A+C
Sbjct: 499 PTTREAAAAQPAASKPANC 517


>gi|83977459 pleckstrin homology-like domain, family A, member 1
           [Homo sapiens]
          Length = 401

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 32/87 (36%), Positives = 44/87 (50%), Gaps = 11/87 (12%)

Query: 405 RPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCE---IPEPR 461
           +P  +P+P   L+P+P+P P+        P+P P  +P P+P P P+P Q      P P 
Sbjct: 306 QPPSQPQPQPQLQPQPQPQPQ--------PQPQPQSQPQPQPQPKPQPQQLHPYPHPHPH 357

Query: 462 PCLQPCEHPEPCPRPEPIPLPAPCPSP 488
           P   P  HP P P P P  +P P P P
Sbjct: 358 PHSHPHSHPHPHPHPHPHQIPHPHPQP 384



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 35/106 (33%), Positives = 50/106 (47%), Gaps = 25/106 (23%)

Query: 366 SCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPR 425
           S P+ +P ++P+P P                   P P P+P+ +P+P    +P+P+P P+
Sbjct: 309 SQPQPQPQLQPQPQPQ------------------PQPQPQPQSQPQP----QPQPKPQPQ 346

Query: 426 QLSEPCLYPEPLPALRP--TPRPVPLPRPGQCEIPEPRPCLQPCEH 469
           QL  P  +P P P   P   P P P P P Q   P P+P  QP  H
Sbjct: 347 QL-HPYPHPHPHPHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPHGH 391



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 31/96 (32%), Positives = 46/96 (47%), Gaps = 9/96 (9%)

Query: 429 EPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPI-PLPAPCPS 487
           +P   P+P P L+P P+P P P        +P+P  QP   P+P P+P+ + P P P P 
Sbjct: 306 QPPSQPQPQPQLQPQPQPQPQP--------QPQPQSQPQPQPQPKPQPQQLHPYPHPHPH 357

Query: 488 PEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRL 523
           P     +   P P   P+ +P+P      +   HRL
Sbjct: 358 PHSHPHSHPHPHPHPHPHQIPHPHPQPHSQPHGHRL 393



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 1/81 (1%)

Query: 458 PEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHE 517
           P+P+P LQP   P+P P+P+P   P P P P+P +     P P   P+P  +P       
Sbjct: 311 PQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKP-QPQQLHPYPHPHPHPHSHPHSHPHPH 369

Query: 518 SSPHRLDTEAPYCGPSSYNQG 538
             PH      P+  P S   G
Sbjct: 370 PHPHPHQIPHPHPQPHSQPHG 390



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 26/88 (29%), Positives = 37/88 (42%), Gaps = 1/88 (1%)

Query: 451 RPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSP-CWGPNPVPY 509
           R  Q  + + +P  QP   P+  P+P+P P P P P  +P  +    P P    P P P+
Sbjct: 296 RQKQQHLVQQQPPSQPQPQPQLQPQPQPQPQPQPQPQSQPQPQPQPKPQPQQLHPYPHPH 355

Query: 510 PGDLGCHESSPHRLDTEAPYCGPSSYNQ 537
           P       S PH      P+  P  + Q
Sbjct: 356 PHPHSHPHSHPHPHPHPHPHQIPHPHPQ 383



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 24/81 (29%), Positives = 32/81 (39%), Gaps = 1/81 (1%)

Query: 330 SSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLD 389
           S P    Q+ PQ  P   P  + +SQ   PQP       +L P+  P P P   P     
Sbjct: 309 SQPQPQPQLQPQPQPQPQPQPQPQSQP-QPQPQPKPQPQQLHPYPHPHPHPHSHPHSHPH 367

Query: 390 QCPESPLQRCPPPAPRPRLRP 410
             P     + P P P+P  +P
Sbjct: 368 PHPHPHPHQIPHPHPQPHSQP 388


>gi|169212026 PREDICTED: keratin associated protein [Homo sapiens]
          Length = 517

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 135/564 (23%), Positives = 180/564 (31%), Gaps = 130/564 (23%)

Query: 24  CSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQVCQVSDQAPCQSQTTQ-VKCQSKTKQVK 82
           CSS+  F+   V   + C  ++     SC   +C  S    CQSQT Q V CQ       
Sbjct: 5   CSSRKCFS---VPATSLCSTEV-----SCGGPICLPSS---CQSQTWQLVTCQDSCGSSS 53

Query: 83  GQAQCQSKTTQVKGQA---------ASQSQTSSVQSQAPCQSEVSYVQCEASQPVQTCFV 133
              QC+  +  V   A            S + S   Q  C    +   CE S  V  C+ 
Sbjct: 54  CGPQCRQPSCPVSSCAQPLCCDPVICEPSCSVSSGCQPVCCEATT---CEPSCSVSNCY- 109

Query: 134 ECAPVCYTET-CYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCG 192
              PVC+  T C   C V N                   CQP    +T C+   S SSC 
Sbjct: 110 --QPVCFEATICEPSCSVSN------------------CCQPVCFEATICEPSCSVSSC- 148

Query: 193 PQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRST 252
               ++  C               C P          C P C           +  S   
Sbjct: 149 ----AQPVC---------------CEPAI--------CEPSCSVSSCCQPVGSEATSCQP 181

Query: 253 SRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR 312
             C+P   +  L   SC  P   EP   S +   PS   P  C  P   +P+    CP  
Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVC-EPSCCQPV----CPTP 236

Query: 313 PISSCSQRRGPKCRIEISSPCCPRQ--VPPQRC------PVEIPPIRRRSQSCGPQPSWG 364
             S  S  +   C      P C       P  C      PV + P+     SC P PS  
Sbjct: 237 TCSVTSSCQAVCCDPSPCEPTCSESSICQPATCVALVCEPVCLRPVCCVQSSCEP-PSVP 295

Query: 365 ASCPELRPHVEP--RPL---PSFCPPRRLDQCPESPLQR-----------CPPPAPRPRL 408
           ++C E    V    +P+   PS C P     C  SP Q            CP P   P  
Sbjct: 296 STCQEPSCCVSSICQPICSEPSPCSPA---VCVSSPCQPTCYVVKRCRSVCPEPVSCPST 352

Query: 409 RPEP------------CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCE 456
              P            C    PR   +P     PC       + RP  RP+  P      
Sbjct: 353 SCRPLSCSPGSSASAICRPTCPRTFYIPSSSKRPC---SATISYRPVSRPICRPICSGL- 408

Query: 457 IPEPRPCLQPCEHPEPCPRPEPIPLPAP-CPSPEPCRETWRSPS-----PCWGPNPVPYP 510
           +   +P +    +   C RP    L  P C +   CR  +  PS      C         
Sbjct: 409 LTYRQPYMTSISYRPACYRPCYSILRRPACVTSYSCRPVYFRPSCTESDSCKRDCKKSTS 468

Query: 511 GDLGCHESSPHRLD-TEAPYCGPS 533
             L C +++P ++D +E   C P+
Sbjct: 469 SQLDCVDTTPCKVDVSEEGPCQPT 492



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 96/396 (24%), Positives = 119/396 (30%), Gaps = 73/396 (18%)

Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228
           P+ CQ Q      CQ     SSCGPQ      C   +           C P         
Sbjct: 32  PSSCQSQTWQLVTCQDSCGSSSCGPQ------CRQPSCPVSSCAQPLCCDPVI------- 78

Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPS 288
            C P C                 +S C P          SCS    ++P         PS
Sbjct: 79  -CEPSCSV---------------SSGCQPVCCEATTCEPSCSVSNCYQPVCFEATICEPS 122

Query: 289 EGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKC--------RIEISSPCCPRQVPP 340
               N C P      I    C    +SSC+Q   P C           +SS C P     
Sbjct: 123 CSVSNCCQPVCFEATICEPSCS---VSSCAQ---PVCCEPAICEPSCSVSSCCQPVGSEA 176

Query: 341 QRC------PVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPES 394
             C      P    P+  +S  C P     + C  +        LPS C P     C  S
Sbjct: 177 TSCQPVLCVPTSCQPVLCKSSCCQPVVCEPSCCSAVCT------LPSSCQPV---VCEPS 227

Query: 395 PLQRCPPPAPRPRLR-PEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPG 453
               C P  P P       C ++   P P     SE  +  +P   +     PV L RP 
Sbjct: 228 C---CQPVCPTPTCSVTSSCQAVCCDPSPCEPTCSESSIC-QPATCVALVCEPVCL-RPV 282

Query: 454 QC--EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511
            C     EP      C+ P  C      P+   C  P PC       SPC    P  Y  
Sbjct: 283 CCVQSSCEPPSVPSTCQEPSCCVSSICQPI---CSEPSPCSPAVCVSSPC---QPTCYVV 336

Query: 512 DLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGP 547
              C    P  +   +  C P S + G  + A C P
Sbjct: 337 KR-CRSVCPEPVSCPSTSCRPLSCSPGSSASAICRP 371



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 89/379 (23%), Positives = 120/379 (31%), Gaps = 67/379 (17%)

Query: 5   QQIQCRLPLQQCCVKGPSFCSSQS--PFAQSQVVVQAPCEMQIVDCP-----ASCPVQVC 57
           Q + C+    Q  V  PS CS+    P +   VV +  C   +   P     +SC    C
Sbjct: 190 QPVLCKSSCCQPVVCEPSCCSAVCTLPSSCQPVVCEPSCCQPVCPTPTCSVTSSCQAVCC 249

Query: 58  QVSDQAPCQSQTTQVK-CQSKT-KQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQS 115
              D +PC+   ++   CQ  T   +  +  C      V+      S  S+ Q  + C S
Sbjct: 250 ---DPSPCEPTCSESSICQPATCVALVCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVS 306

Query: 116 EVSYVQCEASQPVQTCFVECAP-VCYTETCYVECPVQNYV--PCPAPQPVQMYRGRPAVC 172
            +    C    P       C+P VC +  C   C V       CP P        RP  C
Sbjct: 307 SICQPICSEPSP-------CSPAVCVSSPCQPTCYVVKRCRSVCPEPVSCPSTSCRPLSC 359

Query: 173 QPQGRFSTQCQYQGSYSSCGPQFQSRATCNN--YTPQFQLRPSYSSCFPQYRSRTSFSPC 230
            P    S  C               R TC    Y P    RP   S    YR   S   C
Sbjct: 360 SPGSSASAIC---------------RPTCPRTFYIPSSSKRP--CSATISYRP-VSRPIC 401

Query: 231 VPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEG 290
            P C    +Y       +   TS    P        R C    R   C +SY        
Sbjct: 402 RPICSGLLTY------RQPYMTSISYRP-----ACYRPCYSILRRPACVTSY------SC 444

Query: 291 FPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEIS--SPCCPRQVPPQRCPVEIP 348
            P Y  P           C +   S         C++++S   PC P +  P      I 
Sbjct: 445 RPVYFRPSCTESDSCKRDCKKSTSSQLDCVDTTPCKVDVSEEGPCQPTEAKP------IS 498

Query: 349 PIRRRSQSCGPQPSWGASC 367
           P  R + +  P  S  A+C
Sbjct: 499 PTTREAAAAQPAASKPANC 517


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 56/165 (33%), Positives = 66/165 (40%), Gaps = 27/165 (16%)

Query: 358 GPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLE 417
           G QP+  A+C  +  H +   +     PR L+Q   +P    PPP P P L   P  S E
Sbjct: 385 GQQPAAAAACEPV-DHAQSESILKVSQPRALEQQASTP----PPPPPPPLL---PGSSAE 436

Query: 418 PRPRPLPRQLSE-------PCLYPEPLP---ALRPTPRPVPLPRPGQCE-IPEPRPCLQP 466
           P P P P  L             P PLP   A+ P   P+P P PG CE +P P P L  
Sbjct: 437 PPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPG 496

Query: 467 CEHPEPCPRPEPIPLP----APCPSPEPCRETWRSPSPCWGPNPV 507
                 CP P P  LP     P P P P      SP    G   V
Sbjct: 497 L----GCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEV 537



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 28/97 (28%)

Query: 419 RPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRP-- 476
           +PR L +Q S P           P P P PL      E P P         P P P P  
Sbjct: 410 QPRALEQQASTP-----------PPPPPPPLLPGSSAEPPPP---------PPPPPLPSV 449

Query: 477 --EPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511
             + +P  AP P P P       P+P   P P P PG
Sbjct: 450 GAKALP-TAPPPPPLPGLGAMAPPAP---PLPPPLPG 482


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 56/165 (33%), Positives = 66/165 (40%), Gaps = 27/165 (16%)

Query: 358 GPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLE 417
           G QP+  A+C  +  H +   +     PR L+Q   +P    PPP P P L   P  S E
Sbjct: 385 GQQPAAAAACEPV-DHAQSESILKVSQPRALEQQASTP----PPPPPPPLL---PGSSAE 436

Query: 418 PRPRPLPRQLSE-------PCLYPEPLP---ALRPTPRPVPLPRPGQCE-IPEPRPCLQP 466
           P P P P  L             P PLP   A+ P   P+P P PG CE +P P P L  
Sbjct: 437 PPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPPPLPG 496

Query: 467 CEHPEPCPRPEPIPLP----APCPSPEPCRETWRSPSPCWGPNPV 507
                 CP P P  LP     P P P P      SP    G   V
Sbjct: 497 L----GCPPPPPPLLPGMGWGPPPPPPPLLPCTCSPPVAGGMEEV 537



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 31/97 (31%), Positives = 36/97 (37%), Gaps = 28/97 (28%)

Query: 419 RPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRP-- 476
           +PR L +Q S P           P P P PL      E P P         P P P P  
Sbjct: 410 QPRALEQQASTP-----------PPPPPPPLLPGSSAEPPPP---------PPPPPLPSV 449

Query: 477 --EPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPG 511
             + +P  AP P P P       P+P   P P P PG
Sbjct: 450 GAKALP-TAPPPPPLPGLGAMAPPAP---PLPPPLPG 482


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 74/259 (28%), Positives = 102/259 (39%), Gaps = 38/259 (14%)

Query: 219 PQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPP--RRFE 276
           P  R R S SP  P  + +      T   R R+ S   PPPRR    PR  SPP  RR+ 
Sbjct: 553 PPTRRRRSPSPAPPPRRRRTP----TPPPRRRTPS---PPPRRRSPSPRRYSPPIQRRYS 605

Query: 277 PC----SSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSP 332
           P       +  P  P +   +   PP+R   + +S  P++  S  ++RR P    +    
Sbjct: 606 PSPPPKRRTASPPPPPKRRASPSPPPKRR--VSHSPPPKQRSSPVTKRRSPSLSSKHRKG 663

Query: 333 CCP-RQVPPQRCPVEIPPIRRRSQSCGPQ-PSWGASCPELR------PHVEPRPLPSFCP 384
             P R     R P    P +R S S  P+ P   +S P +R      P     P PS  P
Sbjct: 664 SSPSRSTREARSP---QPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRP 720

Query: 385 PRRLDQCPE-SPLQRCPPPAPRPRLR----------PEPCISLEPRPRPLPRQLSEPCLY 433
            RR+ + PE   +++   P+P+   R          PEP     P P P P Q   P   
Sbjct: 721 IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP-PSPVQSQSPSTN 779

Query: 434 PEPLPALRPTPRPVPLPRP 452
             P   ++    P P P P
Sbjct: 780 WSPAVPVKKAKSPTPSPSP 798



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 86/322 (26%), Positives = 114/322 (35%), Gaps = 40/322 (12%)

Query: 219 PQYRSRTSFSPCVPQCQTQGSY-GSFTEQHRSRSTSRCLPPPRRLQLFPR-------SCS 270
           P  R R S SP   + ++  S  GS +    SRS S    PP+R    PR       S S
Sbjct: 334 PPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSAS 393

Query: 271 PPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSR---CPRRPISSCSQRRGPKCRI 327
           PPRR    S    P   +   P     P++S     SR    P R     ++ +G + R 
Sbjct: 394 PPRRRHRPSPPATPPPKTRHSPT----PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE 449

Query: 328 EISSPCCPRQVPPQRCPVE-------IPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLP 380
             S    PR+V       +          +++R Q         +         + RP  
Sbjct: 450 SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR 509

Query: 381 SFCPPRRLDQCPESPLQRCPPPAPRPRLR---PEPCISLEPRPRPLPRQLSEPCLYPEPL 437
           S      + +       R   P+PR R +   P       P P P  R+ S     P P 
Sbjct: 510 SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPS---PAPP 566

Query: 438 PALRPTPRPVPLPR----PGQCEIPEPR---PCLQPCEHPEPCPR-----PEPIPLPAPC 485
           P  R TP P P  R    P +   P PR   P +Q    P P P+     P P P     
Sbjct: 567 PRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRAS 626

Query: 486 PSPEPCRETWRSPSPCWGPNPV 507
           PSP P R    SP P    +PV
Sbjct: 627 PSPPPKRRVSHSPPPKQRSSPV 648



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 51/171 (29%), Positives = 70/171 (40%), Gaps = 15/171 (8%)

Query: 339 PPQRCPVEIPPIRRRSQSCGPQ---PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESP 395
           PP+R     PP RRR+ S  P+   PS     P ++    P P     PP+R    P  P
Sbjct: 566 PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSP-----PPKRRTASPPPP 620

Query: 396 LQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPT--PRPVPLPRPG 453
            +R   P+P P+ R       + R  P+ ++ S P L  +      P+   R    P+P 
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRS-PSLSSKHRKGSSPSRSTREARSPQPN 679

Query: 454 QCEIPEPRP-CLQPCEHPEPCPR---PEPIPLPAPCPSPEPCRETWRSPSP 500
           +   P PRP   Q    P P  R     P    +P PS  P R   R+P P
Sbjct: 680 KRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEP 730



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 60/240 (25%), Positives = 75/240 (31%), Gaps = 54/240 (22%)

Query: 245 EQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPI 304
           E+ R RS SR     R     P    P RR    S SY P R         +P RR  P 
Sbjct: 272 EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRP-------SPRRRPSP- 323

Query: 305 YNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWG 364
                         +RR P  R+           PP R      P+RRR +S        
Sbjct: 324 --------------RRRTPPRRMP----------PPPRHRRSRSPVRRRRRSSASLSGSS 359

Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424
           +S    R    P+      PP+R    P    +R  P A  PR R  P            
Sbjct: 360 SSSSSSRSRSPPKK-----PPKRTSSPPRKT-RRLSPSASPPRRRHRP------------ 401

Query: 425 RQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAP 484
                P   P P     PTP+     R  +  +   R   +  +H     R  P P P P
Sbjct: 402 ----SPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 32/116 (27%), Positives = 42/116 (36%), Gaps = 26/116 (22%)

Query: 385 PRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTP 444
           PRR      SP +R  P   R R R     S  PR R   R                 +P
Sbjct: 172 PRRRKSRSPSPRRRSSP-VRRERKRSH---SRSPRHRTKSR-----------------SP 210

Query: 445 RPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSP 500
            P P  +    E+PEP   ++     E     + + +P P P PEP     + PSP
Sbjct: 211 SPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP-----KEPSP 261


>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
            sapiens]
          Length = 1636

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 46/147 (31%), Positives = 56/147 (38%), Gaps = 10/147 (6%)

Query: 354  SQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRR-LDQCPESPLQRCPPPAPRPRLRPEP 412
            SQ+ GPQP      P   PH+ P   P   PP+      P+  +   PPP    +L P P
Sbjct: 964  SQAFGPQPPQ-QPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGP 1022

Query: 413  C-------ISLEPRPRPLPRQLSEPCLYPEPLPALRPT-PRPVPLPRPGQCEIPEPRPCL 464
                        P P P P Q   P L   P P+ RP  P+  PL   G     +  P  
Sbjct: 1023 AQDPLPAHSGALPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAAPLTIRGPSSAGQSTPSP 1082

Query: 465  QPCEHPEPCPRPEPIPLPAPCPSPEPC 491
                 P P P P P+P   P   P PC
Sbjct: 1083 HLVPSPAPSPGPGPVPPRPPAAEPPPC 1109



 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 57/204 (27%), Positives = 71/204 (34%), Gaps = 62/204 (30%)

Query: 348  PPIRRRSQSCGPQPSWGASCPELRPHVEPR---------PLPSFCPPRRLDQCPESPLQR 398
            PP+     +  PQ     S PEL   V P          P+PS   PR            
Sbjct: 855  PPVAGLPSAPPPQ----FSGPELAMAVRPATTTVDSIQAPIPSHTAPR------------ 898

Query: 399  CPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPA----------------LRP 442
             P P P P   P PC  + P P+PLP   + P    +P+PA                + P
Sbjct: 899  -PNPTPAP---PPPCFPVPP-PQPLPTPYTYPAGAKQPIPAQHHFSSGIPAGFPAPRIGP 953

Query: 443  TPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCP-----------SPEPC 491
             P+P P P P Q   P+P     P +HP   P   P  LP   P            P P 
Sbjct: 954  QPQPHPQPHPSQAFGPQPPQQPLPLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPP 1013

Query: 492  RETWRSPSPCWGPNP-----VPYP 510
              T   P P   P P     +P+P
Sbjct: 1014 LHTQLYPGPAQDPLPAHSGALPFP 1037



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 65/238 (27%), Positives = 84/238 (35%), Gaps = 35/238 (14%)

Query: 297 PPRRSEPIYNSRCPRRPISSCSQRRGPKCRIE------ISSPCCPRQVPPQRCPVEIPPI 350
           PPR + P      PRR  S   +   P   +       ++ P  P        P+  PP 
Sbjct: 717 PPRPTAP--KPLLPRREESEAVEAGDPPEELRSLPPDMVAGPRLPDTFLGSATPLHFPPS 774

Query: 351 RRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRP 410
              S S GP P + +          P P  ++  P +L Q P +P     P AP P L P
Sbjct: 775 PFPS-STGPGPHYLSG---------PLPPGTYSGPTQLIQ-PRAPGPHAMPVAPGPALYP 823

Query: 411 EPC----ISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQP 466
            P     + L PR  P    +S P +   P P +   P   P    G       RP    
Sbjct: 824 APAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFSGPELAMAVRPATTT 883

Query: 467 CEHPE-PCPR---PEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSP 520
            +  + P P    P P P PAP   P PC      P P   P P PY    G  +  P
Sbjct: 884 VDSIQAPIPSHTAPRPNPTPAP---PPPC-----FPVPPPQPLPTPYTYPAGAKQPIP 933



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 17/124 (13%)

Query: 393  ESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPE-PLPALRPTPRPVPLPR 451
            E  LQR   P P    +P    S+  +   LP+   +  L  + P+ +++ T   + +  
Sbjct: 1454 EQVLQRHGVPPP---CKPLASASISQKNH-LPQDSQDLVLGGDVPISSIQATIAKLSIRP 1509

Query: 452  PGQCEIP--------EPRPCLQPCEHPE--PCPRPEPIPLPAPCP-SPEPCRETWRSPSP 500
            PG  E P        EP P L P   PE  P P   P PL +P P +P+P  E     +P
Sbjct: 1510 PGGLESPVASLPGPAEP-PGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAP 1568

Query: 501  CWGP 504
              GP
Sbjct: 1569 SSGP 1572



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 16/43 (37%), Positives = 19/43 (44%)

Query: 375  EPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLE 417
            E  P+PS  PP      PE+P  +  PP P       P  SLE
Sbjct: 1536 ESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSLE 1578


>gi|154800453 tastin isoform 1 [Homo sapiens]
          Length = 778

 Score = 60.8 bits (146), Expect = 3e-09
 Identities = 69/204 (33%), Positives = 76/204 (37%), Gaps = 41/204 (20%)

Query: 359 PQPSWGASC--PELRPHVEPRPLPSFCPPRRLDQCPESPLQR---CPPPAPRPRLRP-EP 412
           P+P     C  P+  P  EP P  +FC  R   + PE  LQ     P P P    RP E 
Sbjct: 501 PKPCLPEECGEPQPCPPAEPGPPEAFC--RSEPEIPEPSLQEQLEVPEPYPPAEPRPLES 558

Query: 413 CISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEP 472
           C   EP      RQ  E    PEP P   P  RP+      + EIPE     Q  E PEP
Sbjct: 559 CCRSEPEIPESSRQ--EQLEVPEPCPPAEP--RPLESYCRIEPEIPESSRQEQ-LEVPEP 613

Query: 473 CPRPEPIPL----------PAPCP-----SPEPC----RETWRSPSPC---WGPNPVPYP 510
           CP  EP PL          P PCP     + EPC    R    S  PC   W       P
Sbjct: 614 CPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWA------P 667

Query: 511 GDLGCHESSPHRLDTEAPYCGPSS 534
                  SS H L    P C   S
Sbjct: 668 ATTSLIFSSQHPLCASPPICSLQS 691



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 52/136 (38%), Positives = 57/136 (41%), Gaps = 20/136 (14%)

Query: 379 LPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPR-PRPLPRQLSEPCLYPEPL 437
           LP  C P   ++C E   Q CPP  P P   PE     EP  P P    L E    PEP 
Sbjct: 500 LPKPCLP---EECGEP--QPCPPAEPGP---PEAFCRSEPEIPEP---SLQEQLEVPEPY 548

Query: 438 PALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPC----PSPEPCR- 492
           P   P  RP+      + EIPE     Q  E PEPCP  EP PL + C      PE  R 
Sbjct: 549 PPAEP--RPLESCCRSEPEIPESSRQEQ-LEVPEPCPPAEPRPLESYCRIEPEIPESSRQ 605

Query: 493 ETWRSPSPCWGPNPVP 508
           E    P PC    P P
Sbjct: 606 EQLEVPEPCPPAEPGP 621



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 57/178 (32%), Positives = 70/178 (39%), Gaps = 44/178 (24%)

Query: 280 SSYLP-LRPSEGFPNYCTPPRRSEPIYNSRCPRR----PISSCSQRRGPKC-------RI 327
           +S+LP L    G P  C P    EP     CP      P + C  R  P+        ++
Sbjct: 488 TSHLPGLLKHSGLPKPCLPEECGEP---QPCPPAEPGPPEAFC--RSEPEIPEPSLQEQL 542

Query: 328 EISSPCCPRQVPPQ----RCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFC 383
           E+  P  P +  P     R   EIP   R+ Q   P+P          P  EPRPL S+C
Sbjct: 543 EVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPC---------PPAEPRPLESYC 593

Query: 384 PPRRLDQCPESPLQR-------CPPPAPRPRLRPEPCISLEPRPRPLPR---QLSEPC 431
             R   + PES  Q        CPP  P P L+P       P P P PR     SEPC
Sbjct: 594 --RIEPEIPESSRQEQLEVPEPCPPAEPGP-LQPSTQGQSGP-PGPCPRVELGASEPC 647



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 29/99 (29%), Positives = 36/99 (36%), Gaps = 17/99 (17%)

Query: 460 PRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPN---PVPYPGDLGCH 516
           P+PCL     PE C  P+P P   P P    CR     P P        P PYP      
Sbjct: 501 PKPCL-----PEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYP------ 549

Query: 517 ESSPHRLDT---EAPYCGPSSYNQGQESGAGCGPGDVFP 552
            + P  L++     P    SS  +  E    C P +  P
Sbjct: 550 PAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRP 588


>gi|33286442 BCL6 co-repressor-like 1 [Homo sapiens]
          Length = 1711

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 64/227 (28%), Positives = 81/227 (35%), Gaps = 25/227 (11%)

Query: 323 PKCRIEISSPCCPRQVPPQ-RCPVEIPPIRRRSQSCGPQ--PSWGASCPELRPHVEPRPL 379
           P C     S   P  VP   + P+ +P     S     Q   S  A  P L P     P 
Sbjct: 202 PICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPA 261

Query: 380 PSFCPPRRLDQCPESPLQRC--PPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPL 437
           P   P    D  P S       P PA  P   P P  +  P P  +P       L   P+
Sbjct: 262 PPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPV 321

Query: 438 P------ALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP--LPAPCPSPE 489
           P       L P P PV  P P       P P   P   P P   P   P  +PA  P+P 
Sbjct: 322 PPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGPPSTPTLIPAFAPTPV 381

Query: 490 PCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYN 536
           P      +P+P + P P P P       ++P  + T AP   P+S++
Sbjct: 382 PA----PTPAPIFTPAPTPMPA------ATPAAIPTSAPI--PASFS 416



 Score = 57.4 bits (137), Expect = 4e-08
 Identities = 56/213 (26%), Positives = 71/213 (33%), Gaps = 10/213 (4%)

Query: 329 ISSPCCPRQVPPQRCPVEIPPIRRRSQSC-GPQPSWGASCPELRPHVEPRPLPSFCPPRR 387
           + +P CP        P  +P   +   S   P P  G    ++   V P P P   P   
Sbjct: 199 LPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLVPVQVATSV-PAPSPPLAPVPA 257

Query: 388 LDQCPESP----LQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPT 443
           L   P S         P       L P P  +    P PL      P   P   P L   
Sbjct: 258 LAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALI 317

Query: 444 PRPVPLPRPGQCEIPEPRPCL--QPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPC 501
             PVP   P     P P P L   P   P   P P  +P+P P PS  P   +  +  P 
Sbjct: 318 QAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVPMPTPTPSSGP--PSTPTLIPA 375

Query: 502 WGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSS 534
           + P PVP P        +P  +    P   P+S
Sbjct: 376 FAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTS 408



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 41/126 (32%), Positives = 44/126 (34%), Gaps = 8/126 (6%)

Query: 368 PELRPHVEPRPLPSFCPPRRLDQCPESP------LQRCPPP--APRPRLRPEPCISLEPR 419
           P   P   P  +P   PP  L Q P  P      L   P P  AP P   P    +    
Sbjct: 296 PLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSV 355

Query: 420 PRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPI 479
           P P P   S P   P  +PA  PTP P P P P     P P P   P   P   P P   
Sbjct: 356 PMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASF 415

Query: 480 PLPAPC 485
            L   C
Sbjct: 416 SLSRVC 421



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 43/172 (25%), Positives = 58/172 (33%), Gaps = 17/172 (9%)

Query: 301 SEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQ 360
           S P+  S     P+ + +   GP   + +S+P       P   PV  PP+        P 
Sbjct: 272 SNPLSVSASVLVPVPASAPPSGP---VPLSAPA----PAPLSVPVSAPPLALIQAPVPPS 324

Query: 361 PSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPR- 419
                  P   P + P  +P+  PP      P  P    P P P P   P    +L P  
Sbjct: 325 APTLVLAPVPTPVLAP--MPASTPPA----APAPP--SVPMPTPTPSSGPPSTPTLIPAF 376

Query: 420 -PRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHP 470
            P P+P     P   P P P    TP  +P   P        R C    + P
Sbjct: 377 APTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAP 428



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 30/123 (24%), Positives = 39/123 (31%), Gaps = 24/123 (19%)

Query: 402 PAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPR 461
           P P P   P P  +  P         S P  +  PL    P P    +P      +P P 
Sbjct: 198 PLPAPICPPAPGSASVPH--------SVPDAFQVPLSVPAPVPHSGLVPVQVATSVPAPS 249

Query: 462 PCLQPCEHPEPCPRPEP----------------IPLPAPCPSPEPCRETWRSPSPCWGPN 505
           P L P     P P   P                +P+PA  P   P   +  +P+P   P 
Sbjct: 250 PPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPV 309

Query: 506 PVP 508
             P
Sbjct: 310 SAP 312



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 29/114 (25%), Positives = 36/114 (31%), Gaps = 6/114 (5%)

Query: 415 SLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCP 474
           +  P P P+          P  +P     P  VP P P    +    P       P P P
Sbjct: 195 NFSPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSGLV----PVQVATSVPAPSP 250

Query: 475 RPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAP 528
              P+P  AP P   P   +  +P        VP P       S P  L   AP
Sbjct: 251 PLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPA--SAPPSGPVPLSAPAP 302


>gi|239744133 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 65/268 (24%), Positives = 93/268 (34%), Gaps = 31/268 (11%)

Query: 41  CEMQIVDCPASCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQS---KTTQVKG 96
           C  Q     ++C  Q  Q S    CQS  T+   C  ++ ++     CQS    +T    
Sbjct: 18  CSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRISSTCSCQSSGTSSTSCSC 77

Query: 97  QAASQSQTSSVQSQAPCQSEVSY--------VQCEAS---------QPVQTCFVECAPVC 139
           Q++  S T S QS     +  S+         +C++S         Q  +T    C+  C
Sbjct: 78  QSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRTSSTSCSCQSSRTSSTSCS--C 135

Query: 140 YTETCYVECPVQNYVPCPAPQPVQMYR-GRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSR 198
            +      C  Q           Q  R      CQ  G  ST C +Q S +S     QS 
Sbjct: 136 QSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSS 195

Query: 199 ATCN-NYTPQFQLRPSYSSCFPQYRSRTSFS------PCVPQCQTQGSYGSFTEQHRSRS 251
            T + +Y+ Q     S  SC     S TS S           CQ+ G+  +      SR+
Sbjct: 196 GTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRT 255

Query: 252 TSRCLPPPRRLQLFPRSCSPPRRFEPCS 279
           +S C     R      SC        CS
Sbjct: 256 SSTCSCQSSRTSSTSCSCQSSGTSSTCS 283



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 49/199 (24%), Positives = 75/199 (37%), Gaps = 26/199 (13%)

Query: 60  SDQAPCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSE--- 116
           S    CQS  T   C  ++ Q      CQS  T      +   Q+S + S   CQS    
Sbjct: 15  SSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTS---STSCNWQSSRISSTCSCQSSGTS 71

Query: 117 VSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQG 176
            +   C++S+   TC  + +    T   +      +   C + +           CQ   
Sbjct: 72  STSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRT----SSTSCSCQSSR 127

Query: 177 RFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQT 236
             ST C  Q S +S        +TC+  T     R S +SC   Y+S  + S C   CQ+
Sbjct: 128 TSSTSCSCQSSRTS--------STCSCQTS----RTSSTSC--SYQSSRTSSTC--SCQS 171

Query: 237 QGSYGSFTEQHRSRSTSRC 255
            G+  +      SR++S C
Sbjct: 172 SGTSSTSCNWQSSRTSSTC 190



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 61/231 (26%), Positives = 85/231 (36%), Gaps = 35/231 (15%)

Query: 51  SCPVQVCQVSDQAPCQ-SQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109
           SC  Q  + S    CQ S+T+   C  ++ +      CQS  T         S+TSS  S
Sbjct: 132 SCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCS 191

Query: 110 -QAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGR 168
            Q+   S  SY  C++S    TC  +      + T    C  Q+                
Sbjct: 192 CQSSGTSSTSY-SCQSSGTSSTCSCQS-----SGTSSTSCSCQS-----------SGTSS 234

Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228
              CQ  G  ST C +Q S +S      S  +C +       R S +SC  Q  S  + S
Sbjct: 235 TCSCQSSGTSSTSCSWQSSRTS------STCSCQS------SRTSSTSCSCQ--SSGTSS 280

Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCS 279
            C   CQ+ G+  +      SR++S C     R      SC   R    CS
Sbjct: 281 TC--SCQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCS 329



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 53/191 (27%), Positives = 75/191 (39%), Gaps = 12/191 (6%)

Query: 51  SCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109
           SC  Q  + S    CQS  T+   C  ++ +      CQS  T     +   S TSS  S
Sbjct: 155 SCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCS 214

Query: 110 QAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRP 169
                +  +   C++S    TC  + +    T   +      +   C + +         
Sbjct: 215 CQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSRT----SSTS 270

Query: 170 AVCQPQGRFST-QCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228
             CQ  G  ST  CQ  G+ SS     QS  T +  + QF  R S +SC  Q  SRTS S
Sbjct: 271 CSCQSSGTSSTCSCQSSGT-SSTSCSCQSSRTSSTCSCQFS-RTSSTSCSCQ-SSRTS-S 326

Query: 229 PCVPQCQTQGS 239
            C   CQ+ G+
Sbjct: 327 TC--SCQSSGT 335



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 46/167 (27%), Positives = 64/167 (38%), Gaps = 15/167 (8%)

Query: 98  AASQSQTSSVQSQAPCQSEV--SYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVP 155
           A  Q + SS  S   CQS    S   C++SQ   TC  + +    T   +    + +   
Sbjct: 7   ACKQHRASS--SSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRISSTCS 64

Query: 156 CPAP-------QPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQF 208
           C +                    CQ  G  ST C +Q S +S   + QS  T +      
Sbjct: 65  CQSSGTSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCRCQSSRTSSTSCSCQ 124

Query: 209 QLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC 255
             R S +SC  Q  SRTS S C   CQT  +  +      SR++S C
Sbjct: 125 SSRTSSTSCSCQ-SSRTS-STC--SCQTSRTSSTSCSYQSSRTSSTC 167



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 38/158 (24%), Positives = 55/158 (34%), Gaps = 22/158 (13%)

Query: 51  SCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109
           SC  Q    S    CQS  T+   C  ++ +      CQS  T     +   S TSS  S
Sbjct: 224 SCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSRTSSTSCSCQSSGTSSTCS 283

Query: 110 QAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRP 169
                +  +   C++S+   TC  +     ++ T    C  Q+                 
Sbjct: 284 CQSSGTSSTSCSCQSSRTSSTCSCQ-----FSRTSSTSCSCQS-----------SRTSST 327

Query: 170 AVCQPQGRFSTQC---QYQGSYSSCGPQFQ--SRATCN 202
             CQ  G  ST C       S +SC  +F   S  +CN
Sbjct: 328 CSCQSSGTSSTSCICWSSGTSSTSCSGRFSGTSSTSCN 365



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 54/231 (23%), Positives = 79/231 (34%), Gaps = 37/231 (16%)

Query: 22  SFCSSQSPFAQSQVVVQAPCEMQIVDCPASCPVQV---------CQ---VSDQAPCQSQ- 68
           S CS QS    S       C  Q     ++C  Q          CQ    S    CQS  
Sbjct: 165 STCSCQSSGTSS-----TSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSG 219

Query: 69  TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQSQAPCQSEVSYVQCEASQPV 128
           T+   C  ++        CQS  T     +   S+TSS  S    ++  +   C++S   
Sbjct: 220 TSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSRTSSTSCSCQSSGTS 279

Query: 129 QTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSY 188
            TC  + +    T      C  Q+                   CQ     ST C  Q S 
Sbjct: 280 STCSCQSSGTSSTS-----CSCQS-----------SRTSSTCSCQFSRTSSTSCSCQSSR 323

Query: 189 SSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGS 239
           +S     QS  T +     +    S +SC  ++ S TS + C   C++ G+
Sbjct: 324 TSSTCSCQSSGTSSTSCICWSSGTSSTSCSGRF-SGTSSTSC--NCRSSGT 371


>gi|33186895 selenoprotein V [Homo sapiens]
          Length = 346

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 51/162 (31%), Positives = 61/162 (37%), Gaps = 19/162 (11%)

Query: 378 PLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPL 437
           P+ +  P         SPL   P PA  P L P P ++  PR  P P     P   P P+
Sbjct: 42  PIRTLTPVLTPSPAGTSPLVLTPAPAQIPTLVPTPALARIPRLVPPPAPAWIPTPVPTPV 101

Query: 438 PALRPTPRP-----------VPLPRPGQ------CEIPEPRPCLQPCEHPEPCPRPEP-I 479
           P   PTP P           VP P P Q        +P     L P    +P P P P +
Sbjct: 102 PVRNPTPVPTPARTLTPPVRVPAPAPAQLLAGIRAALPVLDSYLAPALPLDPPPEPAPEL 161

Query: 480 P-LPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSP 520
           P LP   P P P  +   S S   GP P P P       +SP
Sbjct: 162 PLLPEEDPEPAPSLKLIPSVSSEAGPAPGPLPTRTPLAANSP 203



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 42/138 (30%), Positives = 53/138 (38%), Gaps = 29/138 (21%)

Query: 398 RCPPP--APRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEP--LPALRPTPRPVPLPRPG 453
           R P P   P P     P  +L P   P P   S   L P P  +P L PTP    +PR  
Sbjct: 26  RTPTPLRTPTPVRTRTPIRTLTPVLTPSPAGTSPLVLTPAPAQIPTLVPTPALARIPRL- 84

Query: 454 QCEIPEPRPCLQPCEHPEPCP--RPEPIPLPA---------PCPSPE----------PCR 492
              +P P P   P   P P P   P P+P PA         P P+P           P  
Sbjct: 85  ---VPPPAPAWIPTPVPTPVPVRNPTPVPTPARTLTPPVRVPAPAPAQLLAGIRAALPVL 141

Query: 493 ETWRSPSPCWGPNPVPYP 510
           +++ +P+    P P P P
Sbjct: 142 DSYLAPALPLDPPPEPAP 159



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 74/279 (26%), Positives = 98/279 (35%), Gaps = 40/279 (14%)

Query: 233 QCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFP 292
           Q +T     + T      ST    P P R     R+ +P R   P     L   P+   P
Sbjct: 4   QARTPAPSSARTSTSVRASTPTRTPTPLRTPTPVRTRTPIRTLTPV----LTPSPAGTSP 59

Query: 293 NYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIP-PIR 351
              TP     P   +  P   ++   +   P     I +P  P  VP  R P  +P P R
Sbjct: 60  LVLTPAPAQIP---TLVPTPALARIPRLVPPPAPAWIPTPV-PTPVPV-RNPTPVPTPAR 114

Query: 352 RRSQSC---GPQPSW-----GASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPA 403
             +       P P+       A+ P L  ++ P  LP   PP   +  PE PL     P 
Sbjct: 115 TLTPPVRVPAPAPAQLLAGIRAALPVLDSYLAPA-LPLDPPP---EPAPELPLLPEEDPE 170

Query: 404 PRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPC 463
           P P L+  P +S E  P P P     P     P P L  T R      P    + +P   
Sbjct: 171 PAPSLKLIPSVSSEAGPAPGPLPTRTPLAANSPGPTLDFTFR----ADPSAIGLADP--- 223

Query: 464 LQPCEHPEPCPRPEPIPLPAPCPSP---EPCRETWRSPS 499
                   P P P P P+    PS    + C ET+ S S
Sbjct: 224 --------PIPSPVPSPILGTIPSAISLQNCTETFPSSS 254


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 92/365 (25%), Positives = 119/365 (32%), Gaps = 61/365 (16%)

Query: 157 PAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQ----------SRATCNNYTP 206
           P P P       PA   P    +T         S  P  Q          S+A  +  TP
Sbjct: 316 PVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375

Query: 207 QFQLRPSYSSCFPQYRSRTSFSP---------CVPQCQTQGSYGSFTEQHRS-------R 250
             Q  PS  +  P     +  SP          +   Q   S GS T Q          R
Sbjct: 376 PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR 435

Query: 251 STSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPS--EGFPNYCTP----PRRSEPI 304
            T   L  P R    P   SPP +      +  PL+ S         +P    P ++   
Sbjct: 436 QTQASLTSPSRPASTPPD-SPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSS 494

Query: 305 YNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWG 364
             S  P+ P+SS          +E  S   P  +      +  PP+     S  P P   
Sbjct: 495 LASHSPQAPLSSLIMPP-----LETQSSLAPPSLQTPPASLTTPPLENLP-SLAPPPLQT 548

Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424
           AS P   PH+E  P P+ CP +              PP+P     PE   S+   P   P
Sbjct: 549 ASAPLTTPHLETPPCPAPCPLQA-------------PPSPLTTPPPETPSSIATPPPQAP 595

Query: 425 RQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAP 484
             L+ P L   P P L P   P P       + P P   L P + P P P   P   P  
Sbjct: 596 PALASPPLQGLPSPPLSPLATPPP-------QAP-PXLALPPLQAP-PSPPASPPLSPLA 646

Query: 485 CPSPE 489
            PSP+
Sbjct: 647 TPSPQ 651



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 85/302 (28%), Positives = 102/302 (33%), Gaps = 53/302 (17%)

Query: 257 PPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISS 316
           PPP      P S   P    P S S  P  PS+  P+   PP +  P   +  P  P ++
Sbjct: 667 PPPSPPVQAPFS---PPASPPVSPSATP--PSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721

Query: 317 CSQRR-----GPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELR 371
              +       P  ++  S P  P   P    P  +PP+        P PS  AS P + 
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVP-PSPPASLP-MS 779

Query: 372 PHVEPRPL--PSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSE 429
           P  +P P   P+   P    Q   SP    P  AP       P   L   P   P  L+ 
Sbjct: 780 PLAKPPPQAPPALATPPL--QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837

Query: 430 PCLYPEPLPALRPT---PRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCP 486
           P L   P P   PT   PR  P P P    +  PR  L                  AP P
Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGP-DTSVSGPRLTL----------------ALAPGP 880

Query: 487 SPEPCRETWRSPSPCW-GPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGC 545
            P P     RSPS    GP       DL  H SS      E        Y+ G E GA  
Sbjct: 881 PPPPS----RSPSSTLSGP-------DLAGHSSSATSTPEEL-----RGYDSGPEGGAAA 924

Query: 546 GP 547
            P
Sbjct: 925 SP 926



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 92/359 (25%), Positives = 127/359 (35%), Gaps = 50/359 (13%)

Query: 196 QSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC 255
           Q+ ++  +++PQ    P  S   P   +++S +P  P  QT  +  S T        S  
Sbjct: 490 QALSSLASHSPQ---APLSSLIMPPLETQSSLAP--PSLQTPPA--SLTTPPLENLPSLA 542

Query: 256 LPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPN-YCTPPRRSEPIYNSRCPRRPI 314
            PPP +    P + +P     PC +      P +  P+   TPP  +     +  P+ P 
Sbjct: 543 -PPPLQTASAPLT-TPHLETPPCPAPC----PLQAPPSPLTTPPPETPSSIATPPPQAPP 596

Query: 315 SSCSQRRGPKCRIEISSPCCPRQVPPQRCP--VEIPPIRRRSQSCGPQPSWGASCPELRP 372
           +  S    P  +   S P  P   PP + P  + +PP++         PS  AS P L P
Sbjct: 597 ALAS----PPLQGLPSPPLSPLATPPPQAPPXLALPPLQA-------PPSPPAS-PPLSP 644

Query: 373 HVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCL 432
              P P         L Q P SP     PP+P  +    P  S    P   P   + P L
Sbjct: 645 LATPSPQAPNALAVHLLQAPFSP-----PPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 699

Query: 433 YPEPL---------PALRPTPRPVPLPRPGQCEIP---EPRPCLQPCEHPEPCPRPEPIP 480
              PL         P + P+  P P   P     P    P P   P   P   P P   P
Sbjct: 700 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759

Query: 481 LPAPCPSPEPCRETWRSP-SPCWGPNPVPYPG----DLGCHESSPHRLDTEAPYCGPSS 534
           L A  P   P       P SP   P P   P      L    S P     +AP+   +S
Sbjct: 760 LLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 818



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 70/244 (28%), Positives = 88/244 (36%), Gaps = 47/244 (19%)

Query: 297 PPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQS 356
           P   + P   +  PR+ +SS S+    +      SP   R+ P     ++ P  R  S S
Sbjct: 192 PAPSARPRPPTEGPRKSVSSASEHSTTE-----PSPAARRR-PSAGGGLQRPASRSLSSS 245

Query: 357 CGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISL 416
             P  S   S P  R             PR     P  P Q  P P     LRP      
Sbjct: 246 ATPLSSPARSGPSARG-----------TPR----APAHPSQ--PKPKGLQALRP------ 282

Query: 417 EPRPRPLPRQLSEPCLYP-EPLPALRPTP-----RPVPLPRPGQCEIPEPRPCLQPCEHP 470
            P+  P PR+ + P L P    P   P+P     RPVP P      +P   P       P
Sbjct: 283 -PQVTP-PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP-------P 333

Query: 471 EPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYC 530
            P P   P+PL  P PS  P  +T  SP P   P+  P P        +P  L T  P  
Sbjct: 334 SP-PLATPLPLAPPSPSAPPSLQTLPSP-PATPPSQAP-PSMTTPPMQAPPSLQTIPPIQ 390

Query: 531 GPSS 534
            P S
Sbjct: 391 VPHS 394



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 66/285 (23%), Positives = 80/285 (28%), Gaps = 63/285 (22%)

Query: 267 RSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCR 326
           R   PP        + LP  P    P    PP  S P      P  P +  SQ       
Sbjct: 315 RPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374

Query: 327 IEISSPCCPRQVPPQRCP-------VEIPPIRRRSQS--------------------CGP 359
             + +P   + +PP + P       ++ PP      S                      P
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434

Query: 360 QPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRP--------- 410
           + +  +     RP   P   P    P  L   P  PLQ    PA  P   P         
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASP--PLQTSLSPAVSPLSSPLTIHPLQAL 492

Query: 411 ---------EPCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPR 461
                     P  SL   P      L+ P L   P     P    +P   P         
Sbjct: 493 SSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP--------- 543

Query: 462 PCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNP 506
           P LQ    P   P  E  P PAPCP   P       PSP   P P
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAP-------PSPLTTPPP 581


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 89/329 (27%), Positives = 119/329 (36%), Gaps = 52/329 (15%)

Query: 256 LPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRR--- 312
           LPPP    L P + SPP    P S+S  P       P    PP  S P   ++  +    
Sbjct: 401 LPPP---PLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESP 457

Query: 313 -PI--SSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCG-PQPSWGASCP 368
            P+  ++CS++RG            P   P QR   E         S   P PS     P
Sbjct: 458 PPVVPATCSRKRGR-----------PPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGP 506

Query: 369 -ELRPHVEPRP------LPSFCPP------RRLDQCPESPLQRCPPPAPRPRLRP--EPC 413
            E  P V P+       +  F  P       R+ + P   +   PP  P+  + P   P 
Sbjct: 507 PEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPP 566

Query: 414 ISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEP--RPCLQPCEHPE 471
           I+  P   P+P+   EP   P P  A  P   PVPLP   +  + EP  R      E P 
Sbjct: 567 ITTSP---PVPQ---EPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP 620

Query: 472 PCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCG 531
           P P P P P P+P P+P     + R P     P   P    L  +ES         P  G
Sbjct: 621 PPPAPPPPPAPSPPPAP---ATSSRRPLLLRAPQFTPSEAHLKIYESV-----LTPPPLG 672

Query: 532 PSSYNQGQESGAGCGPGDVFPERRGQDGH 560
                + +   A   P +  P   G+  H
Sbjct: 673 APEAPEPEPPPADDSPAEPEPRAVGRTNH 701



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 68/247 (27%), Positives = 85/247 (34%), Gaps = 25/247 (10%)

Query: 267 RSCSPPRRF---EPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGP 323
           R    PRRF   +P     + + P    P   +PP   EP      PR P    +    P
Sbjct: 538 RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597

Query: 324 KCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPL---- 379
           + R  I      R     R   E+PP         P P    S P        RPL    
Sbjct: 598 EKRRSILREPTFRWTSLTR---ELPP-----PPPAPPPPPAPSPPPAPATSSRRPLLLRA 649

Query: 380 PSFCPPRRLDQCPESPLQRCP---PPAPRPRLRPEPCISLEPRPRPLPR--QLSEPCLYP 434
           P F P     +  ES L   P   P AP P   P      EP PR + R   LS P   P
Sbjct: 650 PQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAP 709

Query: 435 EPLPALRP--TPRPVPLPRPG---QCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPE 489
                ++   +P   P    G   Q ++ +P   LQ    P+  P P+P   P P P   
Sbjct: 710 VVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQM 769

Query: 490 PCRETWR 496
           P  E  R
Sbjct: 770 PPLEKAR 776



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 53/181 (29%), Positives = 66/181 (36%), Gaps = 30/181 (16%)

Query: 270  SPPRRFEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRRGPK----C 325
            SP    EP      PL      P     P R  PI N   P RP S  +    P+     
Sbjct: 1807 SPAPSSEPPGGEDPPLDTDVLVPG---APERHSPIQNLDPPLRPDSGSAPPPAPRSFSGA 1863

Query: 326  RIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPP 385
            RI++ +        P R P+          S GP PS G S   L  H+     P F  P
Sbjct: 1864 RIKVPN------YSPSRRPLG-------GVSFGPLPSPG-SPSSLTHHIPTVGDPDFPAP 1909

Query: 386  RRLDQCPESPLQRCPPPA--------PRPRLRPEPCISLEPRPRPLPRQLSEPCLYPEPL 437
             R  + P SPL   PPP+          P+LR  P  S+     P   +L+ P   P P 
Sbjct: 1910 PRRSRRP-SPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPP 1968

Query: 438  P 438
            P
Sbjct: 1969 P 1969



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 52/176 (29%), Positives = 67/176 (38%), Gaps = 23/176 (13%)

Query: 248 RSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPL-------RPSEG----FPNYCT 296
           R  S +R LPPP      P + SPP    P +SS  PL        PSE     + +  T
Sbjct: 610 RWTSLTRELPPPPPAPPPPPAPSPPP--APATSSRRPLLLRAPQFTPSEAHLKIYESVLT 667

Query: 297 PPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPV--EIPPIRRRS 354
           PP    P      P  P         P+     +    PR  P    PV  E+ P    +
Sbjct: 668 PPPLGAPEAPEPEP-PPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPA 726

Query: 355 QSCGPQPSWGASCP--ELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRL 408
            S GPQ       P   L+  + P+ LP   PP+   Q P SP Q   PP  + R+
Sbjct: 727 LSNGPQTQAQLLQPLQALQTQLLPQALP---PPQPQLQPPPSPQQM--PPLEKARI 777



 Score = 32.7 bits (73), Expect = 0.94
 Identities = 26/76 (34%), Positives = 31/76 (40%), Gaps = 10/76 (13%)

Query: 447 VPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAP--CPSPEPCRETWRSPSPCWGP 504
           +P     + ++P P P   P   P P P P P   P P  CP P P      SP P   P
Sbjct: 391 MPAAEKEEAKLPPP-PLTPPAPSPPP-PLPPPSTSPPPPLCPPPPPP----VSPPPL--P 442

Query: 505 NPVPYPGDLGCHESSP 520
           +P P P      ES P
Sbjct: 443 SPPPPPAQEEQEESPP 458


>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 280

 Score = 57.8 bits (138), Expect = 3e-08
 Identities = 56/223 (25%), Positives = 71/223 (31%), Gaps = 16/223 (7%)

Query: 314 ISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPH 373
           +SS  +  GP    E+ +P      PP   P   P +      C        S P L P 
Sbjct: 34  VSSVGEMTGPYGPREMGTPTLTPSSPPTLTPSNTPTL----TPCSTPTLTPCSTPTLTPS 89

Query: 374 VEPRPLPSFCPPRRLDQCPESPLQRCP--PPAPRPRLRPEPCISLEPRPRPLPRQLSEPC 431
             P   PS  P       P       P   P+  P L P    +L P   P   + S P 
Sbjct: 90  NTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPT 149

Query: 432 LYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPC 491
           L P   P L P+  P   P       P   P L P   P       P   P+  P+  P 
Sbjct: 150 LTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPS 209

Query: 492 RETWRSPSPCWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSS 534
                +PS    P  +P         S+P    +  P   PSS
Sbjct: 210 STPTLTPSNT--PTLIP--------SSTPTLTPSSTPTLTPSS 242



 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 53/204 (25%), Positives = 65/204 (31%), Gaps = 26/204 (12%)

Query: 325 CRIEISSPCCPRQVPPQRCPVEIP---PIRRRSQSCGPQPS-----WGASCPELRPHVEP 376
           C     +PC    + P   P   P   P    S +    PS       +S P L P   P
Sbjct: 73  CSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTP 132

Query: 377 RPLPSFCPPRRLDQCPESPLQRCPP----------PAPRPRLRPEPCISLEPRPRPLPRQ 426
              PS  P       P       P           P+  P L P    +L P  RP+  +
Sbjct: 133 TLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTR 192

Query: 427 LSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHP--EPCPRP------EP 478
            S P L P   P L P+  P   P      IP   P L P   P   P  RP       P
Sbjct: 193 SSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTP 252

Query: 479 IPLPAPCPSPEPCRETWRSPSPCW 502
              P+  P+  P      +PS  W
Sbjct: 253 TLTPSSTPTLTPSSTPTLTPSSLW 276


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 69/260 (26%), Positives = 93/260 (35%), Gaps = 42/260 (16%)

Query: 257 PPPR----RLQLFPRSCSPPRRFEPCSSSYLPLRPSEGFPNYCTP-PRRSEPIYNSRCPR 311
           PPP       QL P  C+P           L +   +       P P    PI     P+
Sbjct: 717 PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQ 776

Query: 312 RPISSCSQRRGPKCRIEISSPCCPRQVPP----QRCPVEIPPIRRRSQSCGPQPSWGASC 367
            P         PK  + I +P   + V P       P   PP+    +    QP++ AS 
Sbjct: 777 AP---------PKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKK----QPAFPASY 823

Query: 368 PELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPC----ISLEPRPRPL 423
               P   P P+P    P++   C +      PPP+P   L P P     I+ +  P P 
Sbjct: 824 IPPSPPTPPVPVPPPTLPKQQSFCAK------PPPSP---LSPVPSVVKQIASQFPPPPT 874

Query: 424 PRQLSEPCLYPEPL---PALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIP 480
           P  +    L P P    P   P  +  P  +P    +P P     P E     P P P P
Sbjct: 875 PPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSP 934

Query: 481 LPAPCPSPEPCRETWRSPSP 500
           +PAP P P P      SP+P
Sbjct: 935 VPAPPPPPPPT----ASPTP 950



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 35/124 (28%), Positives = 45/124 (36%), Gaps = 13/124 (10%)

Query: 400 PPPAPRP-----RLRPEPCISLEPR--PRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRP 452
           PPP P P     +L+P PC    P+    P P ++ +     +  P   P P P+P P P
Sbjct: 715 PPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP 774

Query: 453 GQC------EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNP 506
            Q        IP P               P P P   P         ++  PSP   P P
Sbjct: 775 PQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP 834

Query: 507 VPYP 510
           VP P
Sbjct: 835 VPPP 838



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 43/185 (23%), Positives = 52/185 (28%), Gaps = 69/185 (37%)

Query: 378 PLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLS--------- 428
           P P    P    Q P  PL   PPP P P   P P       P PLP Q +         
Sbjct: 611 PQPKIVTPYTASQ-PSPPLPPPPPPPPPPPPPPPP------PPPPLPSQSAPSAGSAAPM 663

Query: 429 ----------------------------------EPCLYPEPLPALRPTPRPVPLPRPGQ 454
                                             +P +   P   + P P P P P PG 
Sbjct: 664 FVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723

Query: 455 CEIP-EPRPC------------------LQPCEHPEPCPRPEPIPLPAPCPSPEPCRETW 495
                +P PC                  +Q      P   P P P+PAP P   P +   
Sbjct: 724 AMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLV 783

Query: 496 RSPSP 500
             P+P
Sbjct: 784 TIPAP 788



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 5/55 (9%)

Query: 433 YPEPLPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPS 487
           Y   +P L P P+ V      Q     P P L P   P P P P P P P P PS
Sbjct: 602 YTSLVPPLSPQPKIVTPYTASQ-----PSPPLPPPPPPPPPPPPPPPPPPPPLPS 651



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 35/131 (26%), Positives = 42/131 (32%), Gaps = 1/131 (0%)

Query: 441 RPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSP 500
           RP    VP P   Q +I  P    QP     P P P P P P P P P P        + 
Sbjct: 600 RPYTSLVP-PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAG 658

Query: 501 CWGPNPVPYPGDLGCHESSPHRLDTEAPYCGPSSYNQGQESGAGCGPGDVFPERRGQDGH 560
              P  V Y        +S H      P   P   +Q  +      P  V P        
Sbjct: 659 SAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPP 718

Query: 561 GDQGNAFAGVK 571
              G+A A +K
Sbjct: 719 PTPGSAMAQLK 729



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 19/51 (37%), Positives = 23/51 (45%), Gaps = 1/51 (1%)

Query: 412 PCISLEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQCEIPEPRP 462
           P  SL P   P P+ ++ P    +P P L P P P P P P     P P P
Sbjct: 601 PYTSLVPPLSPQPKIVT-PYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650


>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 375

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 59/221 (26%), Positives = 82/221 (37%), Gaps = 19/221 (8%)

Query: 41  CEMQIVDCPASCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAA 99
           C  Q     ++C  Q  Q S    CQS  T+   C  ++ +      CQS  T     + 
Sbjct: 18  CSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSCSC 77

Query: 100 SQSQTSSVQSQAPCQSE-VSYVQC--EASQPVQTCFVECAPVCYTETCYVECPVQNYVPC 156
             S+TSS  S   CQS   S   C  + S+   TC  +      + T    C  Q+    
Sbjct: 78  QSSETSSTCS---CQSSGTSSTSCSWQFSRTSSTCCCQS-----SRTSSTSCSCQSSRTS 129

Query: 157 PAPQPVQMYR-GRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCN-NYTPQFQLRPSY 214
                 Q  R      CQ     ST C YQ S +S     QS  T + +   Q     S 
Sbjct: 130 STSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSST 189

Query: 215 SSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC 255
            SC     S TS+S     CQ+ G+  + + Q    S++ C
Sbjct: 190 CSCQSSGTSSTSYS-----CQSSGTSSTCSCQSSGTSSTSC 225



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 50/199 (25%), Positives = 76/199 (38%), Gaps = 26/199 (13%)

Query: 60  SDQAPCQSQTTQVKCQSKTKQVKGQAQCQSK---TTQVKGQAASQSQTSSVQSQAPCQSE 116
           S    CQS  T   C  ++ Q      CQS    +T    Q++  S T S QS     + 
Sbjct: 15  SSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTS 74

Query: 117 VSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRPAVCQPQG 176
            S   C++S+   TC  + +    T   +      +   C + +           CQ   
Sbjct: 75  CS---CQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSRT----SSTSCSCQSSR 127

Query: 177 RFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQT 236
             ST C  Q S +S        +TC+  T     R S +SC   Y+S  + S C   CQ+
Sbjct: 128 TSSTSCSCQSSRTS--------STCSCQTS----RTSSTSC--SYQSSRTSSTC--SCQS 171

Query: 237 QGSYGSFTEQHRSRSTSRC 255
            G+  +      SR++S C
Sbjct: 172 SGTSSTSCNWQSSRTSSTC 190



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 58/215 (26%), Positives = 84/215 (39%), Gaps = 14/215 (6%)

Query: 51  SCPVQVCQVSDQAPCQ-SQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109
           SC  Q  + S    CQ S+T+   C  ++ +      CQS  T         S+TSS  S
Sbjct: 132 SCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSSTCS 191

Query: 110 -QAPCQSEVSYVQCEASQPVQTCFVECAPV------CYTETCYVECPVQNYVPCPAPQPV 162
            Q+   S  SY  C++S    TC  + +        C +      C  Q+          
Sbjct: 192 CQSSGTSSTSY-SCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSW 250

Query: 163 QMYR-GRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQY 221
           Q  R      CQ  G  ST C  Q S +S     QS  T +        R S S+C  Q+
Sbjct: 251 QSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSCQSSRTS-STCSCQF 309

Query: 222 RSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRCL 256
            SRTS + C   CQ+  +  + + Q    S++ C+
Sbjct: 310 -SRTSSTSC--SCQSSRTSSTCSCQSSGTSSTSCI 341



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 56/231 (24%), Positives = 80/231 (34%), Gaps = 23/231 (9%)

Query: 51  SCPVQVCQVSDQA-PCQSQTTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQ-TSSVQ 108
           SC  Q  + S  +  CQS  T   C  +T +      C  ++++     + QS  TSS  
Sbjct: 120 SCSCQSSRTSSTSCSCQSSRTSSTCSCQTSRT-SSTSCSYQSSRTSSTCSCQSSGTSSTS 178

Query: 109 SQAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGR 168
                    S   C++S    T +  C     + TC  +    +   C            
Sbjct: 179 CNWQSSRTSSTCSCQSSGTSSTSY-SCQSSGTSSTCSCQSSGTSSTSCSCQ---SSGTSS 234

Query: 169 PAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFS 228
              CQ  G  ST C +Q S +S     QS  T            S +SC  Q  S  + S
Sbjct: 235 TCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGT------------SSTSCSCQ--SSGTSS 280

Query: 229 PCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCS 279
            C   CQ+ G+  +      SR++S C     R      SC   R    CS
Sbjct: 281 TC--SCQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCS 329



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 38/158 (24%), Positives = 55/158 (34%), Gaps = 22/158 (13%)

Query: 51  SCPVQVCQVSDQAPCQSQ-TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSVQS 109
           SC  Q    S    CQS  T+   C  ++ +      CQS  T     +   S TSS  S
Sbjct: 224 SCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCS 283

Query: 110 QAPCQSEVSYVQCEASQPVQTCFVECAPVCYTETCYVECPVQNYVPCPAPQPVQMYRGRP 169
                +  +   C++S+   TC  +     ++ T    C  Q+                 
Sbjct: 284 CQSSGTSSTSCSCQSSRTSSTCSCQ-----FSRTSSTSCSCQS-----------SRTSST 327

Query: 170 AVCQPQGRFSTQC---QYQGSYSSCGPQFQ--SRATCN 202
             CQ  G  ST C       S +SC  +F   S  +CN
Sbjct: 328 CSCQSSGTSSTSCICWSSGTSSTSCSGRFSGTSSTSCN 365



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 48/170 (28%), Positives = 63/170 (37%), Gaps = 21/170 (12%)

Query: 98  AASQSQTSSVQSQAPCQSEV--SYVQCEASQPVQTCFVECAPVCYT----------ETCY 145
           A  Q + SS  S   CQS    S   C++SQ   TC  + +    T           TC 
Sbjct: 7   ACKQHRASS--SSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRTSSTCS 64

Query: 146 VECPVQNYVPCPAPQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYT 205
            +    +   C               CQ  G  ST C +Q S +S     QS  T +   
Sbjct: 65  CQSSGTSSTSCSCQ---SSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSC 121

Query: 206 PQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC 255
                R S +SC  Q  SRTS S C   CQT  +  +      SR++S C
Sbjct: 122 SCQSSRTSSTSCSCQ-SSRTS-STC--SCQTSRTSSTSCSYQSSRTSSTC 167



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 53/202 (26%), Positives = 73/202 (36%), Gaps = 21/202 (10%)

Query: 51  SCPVQVCQVSDQAPCQSQ---TTQVKCQSKTKQVKGQAQCQSKTTQVKGQAASQSQTSSV 107
           SC  Q  + S    CQS    +T   CQS          CQS  T     +   S TSS 
Sbjct: 178 SCNWQSSRTSSTCSCQSSGTSSTSYSCQSSG--TSSTCSCQSSGTSSTSCSCQSSGTSST 235

Query: 108 QSQAPCQSE-VSYVQC--EASQPVQTCFVECAPV------CYTETCYVECPVQNYVPCPA 158
            S   CQS   S   C  ++S+   TC  + +        C +      C  Q+      
Sbjct: 236 CS---CQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSST 292

Query: 159 PQPVQMYR-GRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSC 217
               Q  R      CQ     ST C  Q S +S     QS  T +     +    S +SC
Sbjct: 293 SCSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCSCQSSGTSSTSCICWSSGTSSTSC 352

Query: 218 FPQYRSRTSFSPCVPQCQTQGS 239
             ++ S TS + C   C++ G+
Sbjct: 353 SGRF-SGTSSTSC--NCRSSGT 371



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 16/102 (15%)

Query: 172 CQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCFPQYRSRTSFSPCV 231
           CQ  G  ST C +Q S +S     QS  T            S +SC  Q  S  + S C 
Sbjct: 42  CQSSGTSSTSCNWQSSRTSSTCSCQSSGT------------SSTSCSCQ--SSETSSTC- 86

Query: 232 PQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPR 273
             CQ+ G+  +      SR++S C     R      SC   R
Sbjct: 87  -SCQSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSCSCQSSR 127


>gi|71274152 hypothetical protein LOC388939 [Homo sapiens]
          Length = 1288

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 72/278 (25%), Positives = 100/278 (35%), Gaps = 44/278 (15%)

Query: 239  SYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEP-----CSSSYLPLRPSEGFPN 293
            S+ S      S+ST     P    +  P    P RR         S S L L PS+   +
Sbjct: 842  SFASLESPESSKSTENS--PKETQEPGPGEAGPTRRTWASPKLRASVSPLDLLPSKSTAS 899

Query: 294  YCTPPRRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRR 353
               P        +S  P    SSC  R   K  +++SSP    Q P  +        +  
Sbjct: 900  LTKP--------HSTGPGSGRSSCQPR---KPALDLSSPPATSQSPEVKGGTWSQAEKAT 948

Query: 354  SQSCGPQPS--WGASCPELRPH-------VEPR-------PLPSFCPPRRLDQCPESPLQ 397
            S    P+ +  W  S P    +         PR       P+     P R    P++  +
Sbjct: 949  SLYRQPRKAIAWHHSGPPSGQNRTSESSLARPRQSRERSPPVGRKASPTRTHWVPQADKR 1008

Query: 398  RCPPPAPRPRLRPEP-CISLEPRPRPLPRQLSEPCLYPEPLPALRPT-PRPVPLPRPGQC 455
            R   P+     +P P  +   P P   PR LS P       P  +P  P P P   P QC
Sbjct: 1009 RRSLPSSYRPAQPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAPAQC 1068

Query: 456  EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRE 493
            ++P P     P +HPE  P   P  +P+P P   P +E
Sbjct: 1069 KVPSP-----PTQHPEASP---PFSIPSPSPPMSPSQE 1098



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 77/307 (25%), Positives = 104/307 (33%), Gaps = 56/307 (18%)

Query: 232  PQCQTQGSYGSFTEQHRSRSTSRCLPP------PRRLQLFPRSCSPPRRFEPCSSSYLPL 285
            P  Q + S  S     +SR  S   PP      P R    P++    +R     SSY P 
Sbjct: 966  PSGQNRTSESSLARPRQSRERS---PPVGRKASPTRTHWVPQA---DKRRRSLPSSYRPA 1019

Query: 286  RPSEG----------FPNYCTPP---RRSEPIYNSRCPRRPISSCSQRRGPKCRIEISSP 332
            +PS             P   +PP   RR+ P +  + P  P  S       +C++     
Sbjct: 1020 QPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAP----AQCKVPSPPT 1075

Query: 333  CCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCP 392
              P   PP   P   PP+    +    + S  +    +   V       FCP        
Sbjct: 1076 QHPEASPPFSIPSPSPPMSPSQEHKETRDSEDSQA--VIAKVSGNTHSIFCPATSSLFEA 1133

Query: 393  ESPLQRCPPPAPRPRLRPEPCISLEPRPRPLPRQLSEPCLYPE-----PLPALRPTP--- 444
            + PL    P  P P L PE    L   P    +  S P L  +      L AL P P   
Sbjct: 1134 KPPLSTAHPLTP-PSLPPEAGGPL-GNPAECWKNSSGPWLRADSQRRAALCALNPLPFLR 1191

Query: 445  RPVPLPRPGQCEIPEPRPCLQPC-----------EHPEPCPRPEPIPLPAPCPSPEPCRE 493
            R     +PG    P+P P L P               E  P+ +  P  +PC SPE    
Sbjct: 1192 RTASDRQPG--GRPQP-PTLDPTSTSYESQLGQNSSSEESPKKDTEPGSSPC-SPELQGG 1247

Query: 494  TWRSPSP 500
            T R+  P
Sbjct: 1248 TRRASPP 1254


>gi|117938768 GNAS complex locus alex [Homo sapiens]
          Length = 626

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 81/294 (27%), Positives = 115/294 (39%), Gaps = 66/294 (22%)

Query: 263 QLFPRSCSPP--RRFEPCSSSYLPLRP----------------SEGFPNYCTPPRRSEPI 304
           +L PRS  P   +R  P  ++ LPLR                   GFP       +S   
Sbjct: 134 ELLPRSPKPSGLQRLAPEEATALPLRRLCHLSLMEKDLGTTAHPRGFPELS---HKSTAA 190

Query: 305 YNSRCPRRPISSCSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQPSWG 364
            +SR  R  + S S    P+ R+   S     Q P    P  +  +   S++  P    G
Sbjct: 191 ASSRQSRPRVRSASLP--PRTRLPSGS-----QAPSAAHPKRLSDLLLTSRAAAP----G 239

Query: 365 ASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRLRPEPCISLEPRPRPLP 424
              P+ R  +   PL S   P      P+S L   P  +P P++R       +P+ R   
Sbjct: 240 WRSPDPRSRLAAPPLGSTTLPSTWT-APQSRLTARPSRSPEPQIRESE--QRDPQLRRKQ 296

Query: 425 RQLSEPCL------YP----EPLPALRPTP--------RPVPLPRPGQCE-IPEP---RP 462
           ++  EP +      YP    +PLP  +P          +P P+  PGQ + IP P   +P
Sbjct: 297 QRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQP 356

Query: 463 CLQPCEHPEPCPRP-EPIPLPAPCPSPEPCRETWRSPSPCWG----PNPVPYPG 511
            L P  H +P P P +P+P   P P P P R     P P  G    P P+  PG
Sbjct: 357 ILTP-GHSQPIPTPGQPLP---PQPIPTPGRPLTPQPIPTPGRPLTPQPIQMPG 406



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 79/288 (27%), Positives = 107/288 (37%), Gaps = 50/288 (17%)

Query: 232 PQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQLFPRSCSPPRRFEPCSSSYLPLRPSEGF 291
           P+   + +  + + Q R R  S  LPP  RL   P     P    P   S L L      
Sbjct: 181 PELSHKSTAAASSRQSRPRVRSASLPPRTRL---PSGSQAPSAAHPKRLSDLLLTSRAAA 237

Query: 292 PNYCTPPRRSEPIYNSRCPRRPISSC---SQRRGPKCRIEISSPCCPRQVPPQRCPVEIP 348
           P + +P  RS      R    P+ S    S    P+ R+       P   P  R   +  
Sbjct: 238 PGWRSPDPRS------RLAAPPLGSTTLPSTWTAPQSRLTARPSRSPE--PQIRESEQRD 289

Query: 349 PIRRRSQSCGPQPSWGASCPELRPHVEPRPLPSFCPPRRLDQCPESPLQRCPPPAPRPRL 408
           P  RR Q    +P        L P  E +      P R  D  P    QR P P     L
Sbjct: 290 PQLRRKQQRWKEP--------LMPRREEK-----YPLRGTDPLPPGQPQRIPLPGQP--L 334

Query: 409 RPEPCISL-EPRPRPLPRQLSEPCLYP----------EPLPALR-PTP----RPVPLPRP 452
           +P+P ++  +P+  P P Q  +P L P          +PLP    PTP     P P+P P
Sbjct: 335 QPQPILTPGQPQKIPTPGQ-HQPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTP 393

Query: 453 GQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSP 500
           G+   P+P   +Q    P   P P  +  P    SP+  R+T   P P
Sbjct: 394 GRPLTPQP---IQMPGRPLRLPPPLRLLRPGQPMSPQ-LRQTQGLPLP 437


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 96/352 (27%), Positives = 119/352 (33%), Gaps = 59/352 (16%)

Query: 159 PQPVQMYRGRPAVCQPQGRFSTQCQYQGSYSSCGPQFQSRATCNNYTPQFQLRPSYSSCF 218
           P+P    R RP    P+   S+  ++  +  S               P  + RPS     
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPS---------------PAARRRPSAGGGL 225

Query: 219 PQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRC-----LPPPRRLQ-LFPRSCSPP 272
            +  SR+  S   P      S  S      +R T R       P P+ LQ L P   +PP
Sbjct: 226 QRPASRSLSSSATPLSSPARSGPS------ARGTPRAPAHPSQPKPKGLQALRPPQVTPP 279

Query: 273 RR-----FEPCSSSYLPLRPSEGFPNYCTPPRRSEPIYNSRCPRRPISSCSQRR----GP 323
           R+       P SSS L        P+   PP  S P      P  P +  SQ       P
Sbjct: 280 RKDAAPALGPLSSSPLAT------PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 333

Query: 324 KCRIEIS----SPCCPRQVPPQRCP--VEIPPIRRRSQSCGPQPSWGASCPELRPHVEPR 377
             +   S     P  P   PP + P  + +PP++         PS  AS P L P   P 
Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA-------PPSPPAS-PPLSPLATPS 385

Query: 378 PLPSFCPPRRLDQCPESPLQRCPPPAP-RPRLRPEPCISLEPRPRPLPRQLSEPCLYPEP 436
           P         L Q P SP    P  AP  P   P    S  P P   P  L+ P L   P
Sbjct: 386 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP-PSQAPPSLAAPPLQVPP 444

Query: 437 LPALRPTPRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSP 488
            P   P   P   P P Q   P   P LQ  + P   P     P     PSP
Sbjct: 445 SPPASPPMSPSATP-PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 105/373 (28%), Positives = 120/373 (32%), Gaps = 81/373 (21%)

Query: 205 TPQFQLRPSYSSCFPQYRSRTSFSPCVPQCQTQGSYGSFTEQHRSRSTSRCLPPPRRLQL 264
           TP     PS S+  P         P  P  Q   S GS T Q    +T   LP P    L
Sbjct: 297 TPSPSAPPSPSA--PPSLQTLPSPPATPPSQATTSLGSPTLQ----ATHSFLPSPPLSPL 350

Query: 265 F-------PRSCSPPRRFEPCSSSYLPLRP----SEGFPN----------YCTPPRRSEP 303
                   P    PP +  P   +  PL P    S   PN          +  PP  S P
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP--SPP 408

Query: 304 IYNSRCPRRPISS--CSQRRGPKCRIEISSPCCPRQVPPQRCPVEIPPIRRRSQSCGPQP 361
           +   + P  P +S   S    P  +   S    P QVPP   P   PP+   S S  P P
Sbjct: 409 V---QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS--PPASPPM---SPSATPPP 460

Query: 362 SWGASCPELRPHVEPRPLPSFCPPRRLD---QCPESPLQRCPPPAPRPRLRPEPCISLEP 418
              A  P   P ++    P   PP       Q   SP    P  AP       P   L  
Sbjct: 461 Q--APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518

Query: 419 RPRPLPRQLSEPCLYPEPLPALRPT---PRPVPLPRPGQCEIPEPRPCLQPCEHPEPCPR 475
            P   P  L+ P L   P P   PT   PR  P P P    +  PR  L           
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP-DTSVSGPRLTL----------- 566

Query: 476 PEPIPLPAPCPSPEPCRETWRSPSPCW-GPNPVPYPGDLGCHESSPHRLDTEAPYCGPSS 534
                  AP P P P     RSPS    GP       DL  H SS      E        
Sbjct: 567 -----ALAPGPPPPPS----RSPSSTLSGP-------DLAGHSSSATSTPEEL-----RG 605

Query: 535 YNQGQESGAGCGP 547
           Y+ G E GA   P
Sbjct: 606 YDSGPEGGAAASP 618



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 63/235 (26%), Positives = 83/235 (35%), Gaps = 41/235 (17%)

Query: 313 PISSCSQRRGPKCRIEISSPCCPRQVPPQ-----RCPVEIPPIRRRSQSCGP-------Q 360
           P+SS + R GP  R    +P  P Q  P+     R P   PP +  + + GP        
Sbjct: 239 PLSSPA-RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297

Query: 361 PSWGAS-CPELRPHVEPRPLPSFCPPRR----------------LDQCPESPLQRCPPPA 403
           PS  A   P   P ++  P P   PP +                L   P SPL   PP A
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 357

Query: 404 P----RPRLR--PEPCIS--LEPRPRPLPRQLSEPCLYPEPLPALRPTPRPVPLPRPGQC 455
           P     P L+  P P  S  L P   P P+  +   ++    P   P   PV  P     
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 456 EIPEPRPCLQPCEHPEPCPRPEPIPLPAPCPSPEPCRETWRSPSPCWGPNPVPYP 510
             P       P + P     P P+ +P P P   P      +P P   P P+  P
Sbjct: 418 SPPVSPSATPPSQAPPSLAAP-PLQVP-PSPPASPPMSPSATPPP-QAPPPLAAP 469


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.464 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,655,340
Number of Sequences: 37866
Number of extensions: 2832944
Number of successful extensions: 29730
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 316
Number of HSP's successfully gapped in prelim test: 1169
Number of HSP's that attempted gapping in prelim test: 13261
Number of HSP's gapped (non-prelim): 8116
length of query: 579
length of database: 18,247,518
effective HSP length: 108
effective length of query: 471
effective length of database: 14,157,990
effective search space: 6668413290
effective search space used: 6668413290
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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