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Search of human proteins with 67782362
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo
sapiens]
(1369 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapi... 2712 0.0
gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1... 579 e-165
gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo ... 576 e-164
gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2... 556 e-158
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 450 e-126
gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 ... 424 e-118
gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 ... 424 e-118
gi|166851804 tudor domain containing 9 [Homo sapiens] 304 4e-82
gi|38505213 YTH domain containing 2 [Homo sapiens] 288 3e-77
gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapi... 282 2e-75
gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapi... 243 7e-64
gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapi... 243 9e-64
gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapi... 228 3e-59
gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapi... 219 2e-56
gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens] 175 3e-43
gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapi... 174 4e-43
gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens] 167 8e-41
gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box po... 152 3e-36
gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapi... 139 2e-32
gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Hom... 135 3e-31
gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo... 91 1e-17
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 51 9e-06
gi|221219020 NYD-SP11 protein [Homo sapiens] 49 3e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 48 6e-05
gi|120587019 zinc finger protein 318 [Homo sapiens] 47 1e-04
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 46 2e-04
gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo sap... 45 5e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 45 6e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 45 6e-04
gi|148746195 trichohyalin [Homo sapiens] 44 0.001
>gi|67782362 DEAH (Asp-Glu-Ala-His) box polypeptide 29 [Homo sapiens]
Length = 1369
Score = 2712 bits (7030), Expect = 0.0
Identities = 1369/1369 (100%), Positives = 1369/1369 (100%)
Query: 1 MGGKNKKHKAPAAAVVRAAVSASRAKSAEAGIAGEAQSKKPVSRPATAAAAAAGSREPRV 60
MGGKNKKHKAPAAAVVRAAVSASRAKSAEAGIAGEAQSKKPVSRPATAAAAAAGSREPRV
Sbjct: 1 MGGKNKKHKAPAAAVVRAAVSASRAKSAEAGIAGEAQSKKPVSRPATAAAAAAGSREPRV 60
Query: 61 KQGPKIYSFNSTNDSSGPANLDKSILKVVINNKLEQRIIGVINEHKKQNNDKGMISGRLT 120
KQGPKIYSFNSTNDSSGPANLDKSILKVVINNKLEQRIIGVINEHKKQNNDKGMISGRLT
Sbjct: 61 KQGPKIYSFNSTNDSSGPANLDKSILKVVINNKLEQRIIGVINEHKKQNNDKGMISGRLT 120
Query: 121 AKKLQDLYMALQAFSFKTKDIEDAMTNTLLYGGDLHSALDWLCLNLSDDALPEGFSQEFE 180
AKKLQDLYMALQAFSFKTKDIEDAMTNTLLYGGDLHSALDWLCLNLSDDALPEGFSQEFE
Sbjct: 121 AKKLQDLYMALQAFSFKTKDIEDAMTNTLLYGGDLHSALDWLCLNLSDDALPEGFSQEFE 180
Query: 181 EQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQ 240
EQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQ
Sbjct: 181 EQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQ 240
Query: 241 NEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKIRKF 300
NEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKIRKF
Sbjct: 241 NEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKIRKF 300
Query: 301 QREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKE 360
QREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKE
Sbjct: 301 QREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKE 360
Query: 361 PHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDD 420
PHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDD
Sbjct: 361 PHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDD 420
Query: 421 VLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSDAEKKREELN 480
VLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSDAEKKREELN
Sbjct: 421 VLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSDAEKKREELN 480
Query: 481 KMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLES 540
KMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLES
Sbjct: 481 KMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLES 540
Query: 541 ANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSG 600
ANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSG
Sbjct: 541 ANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSG 600
Query: 601 KSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCG 660
KSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCG
Sbjct: 601 KSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCG 660
Query: 661 YQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKE 720
YQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKE
Sbjct: 661 YQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKE 720
Query: 721 ILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKD 780
ILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKD
Sbjct: 721 ILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKD 780
Query: 781 SEYCQKFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYM 840
SEYCQKFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYM
Sbjct: 781 SEYCQKFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYM 840
Query: 841 NPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKV 900
NPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKV
Sbjct: 841 NPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKV 900
Query: 901 IALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESS 960
IALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESS
Sbjct: 901 IALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESS 960
Query: 961 QMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCL 1020
QMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCL
Sbjct: 961 QMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCL 1020
Query: 1021 HIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNV 1080
HIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNV
Sbjct: 1021 HIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNV 1080
Query: 1081 KIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYN 1140
KIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYN
Sbjct: 1081 KIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYN 1140
Query: 1141 AYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWE 1200
AYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWE
Sbjct: 1141 AYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWE 1200
Query: 1201 GNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSS 1260
GNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSS
Sbjct: 1201 GNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSS 1260
Query: 1261 VNRDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQ 1320
VNRDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQ
Sbjct: 1261 VNRDLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLSIDGWIYFQ 1320
Query: 1321 APVKIAVIFKQLRVLIDSVLRKKLENPKMSLENDKILQIITELIKTENN 1369
APVKIAVIFKQLRVLIDSVLRKKLENPKMSLENDKILQIITELIKTENN
Sbjct: 1321 APVKIAVIFKQLRVLIDSVLRKKLENPKMSLENDKILQIITELIKTENN 1369
>gi|167830433 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 1
[Homo sapiens]
Length = 1008
Score = 579 bits (1493), Expect = e-165
Identities = 349/886 (39%), Positives = 530/886 (59%), Gaps = 48/886 (5%)
Query: 497 NKLKQQQQQ--QQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNLFR 554
NKL Q+++ Q+ + N + E L+ + + +L+ +EDL+ +N R
Sbjct: 138 NKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDG-TLDQKLLEDLQKKKNDLR 196
Query: 555 KLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLL 614
Y ++ R++LP + + +V + H+V V++GETG GK+TQV F+L++ +
Sbjct: 197 -------YIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYI 249
Query: 615 LNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACEST- 673
+ S C IVCTQPRRISA+S+A RV E G G GYQIR++SR
Sbjct: 250 -ERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNST---GYQIRLQSRLPRKQG 305
Query: 674 RLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILM 733
+LYCTTG++L+ LQ D LS+VSH+++DE+HER++QSD L+ ++K++L RSDL +ILM
Sbjct: 306 SILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILM 365
Query: 734 SATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEE 793
SAT+++EKFS YF +CP++ I G ++PV + LED+IE+ +V E+ E+ +F +
Sbjct: 366 SATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQ-KEHRSQFKRGFMQ 424
Query: 794 VTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILEL 853
+N K Y+E P + ++YS+ T I M K++L+LI+ L
Sbjct: 425 GHVNRQEKEEKEAIYKERWPDY------VRELRRRYSASTVDVIEMMEDDKVDLNLIVAL 478
Query: 854 LAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQA 913
+ Y+ + +GA+L+FLPG +I L+DLL + F S+++ +I LHS++ T +Q
Sbjct: 479 IRYIVLEEE----DGAILVFLPGWDNISTLHDLLMSQVMFKSDKFLIIPLHSLMPTVNQT 534
Query: 914 AAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKA 973
F PPGVRKIV+ATNIAET ITI DVV+VID G+ KE + + +S++ +VSKA
Sbjct: 535 QVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKA 594
Query: 974 SALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDF 1033
+A QR+GRAGRV+ G C+ +Y R DY +PEILR PLEELCL I LG F
Sbjct: 595 NAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYF 654
Query: 1034 LSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFG 1093
LS+ +DPP + + ++ L ++ A + E +LTPLG HLA LPV IGKM++FGA+F
Sbjct: 655 LSRLMDPPSNEAVLLSIRHLMELNALDKQE-ELTPLGVHLARLPVEPHIGKMILFGALFC 713
Query: 1094 CLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAM-ADSDHLTIYNAYLGWKKARQEG 1152
CLDPV T+AA ++ K PF P+G++ AD + LA SDHLT+ NA+ GW++AR+
Sbjct: 714 CLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRR- 772
Query: 1153 GYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQE 1212
G+R E YC FL+ +L L ++K + + + AGF SS E N ++
Sbjct: 773 GFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESN-----INSDN 827
Query: 1213 IALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQT---HG 1269
++KAV+ AGLY V KI ++ K+ + G VHP SVN + QT +
Sbjct: 828 EKIIKAVICAGLYPKVAKI--RLNLGKKRKMVKVYTKTDGLVAVHPKSVNVE-QTDFHYN 884
Query: 1270 WLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQ--HRERLLSIDGWIYFQAPVKIAV 1327
WL+Y K+R + +YL + T ++P+ +L FGGDI +Q + + +++D WI FQ+P +IA
Sbjct: 885 WLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAH 944
Query: 1328 IFKQLRVLIDSVLRKKLENPKMSLEND------KILQIITELIKTE 1367
+ K+LR +D +L++K+E+P ND +L I +LIKT+
Sbjct: 945 LVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ 990
>gi|39777586 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 [Homo
sapiens]
Length = 1386
Score = 576 bits (1484), Expect = e-164
Identities = 355/941 (37%), Positives = 549/941 (58%), Gaps = 73/941 (7%)
Query: 487 PRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSD----EDFSALSLESAN 542
P + F++ + ++++ + ++ ++ ES+ NL D+ A S+ + N
Sbjct: 459 PNNSFVSNQIPEVEKASESEESDEDDGPAPVIVENESYVNLKKKISKRYDWQAKSVHAEN 518
Query: 543 VEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKS 602
+ + FR Q++ ++Q +L+ERQ LP ++ R++I+ L++H+VVV++G TG GK+
Sbjct: 519 GK----ICKQFRMKQASRQFQSILQERQSLPAWEERETILNLLRKHQVVVISGMTGCGKT 574
Query: 603 TQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQ 662
TQ+P F+L+D L N NI+CTQPRRISA+S+A RV E G GYQ
Sbjct: 575 TQIPQFILDDSL-NGPPEKVANIICTQPRRISAISVAERVAKERAERVG-----LTVGYQ 628
Query: 663 IRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEIL 722
IR+ES +TRLLYCTTGVLLR+L+ D L VSH+IVDEVHER+ +SDFLL++LK+I+
Sbjct: 629 IRLESVKSSATRLLYCTTGVLLRRLEGDTALQGVSHIIVDEVHERTEESDFLLLVLKDIV 688
Query: 723 QKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSE 782
+R L +ILMSAT+++E FS YF CP++ I GR++PV+ F LED I T +VL+ S
Sbjct: 689 SQRPGLQVILMSATLNAELFSDYFNSCPVITIPGRTFPVDQFFLEDAIAVTRYVLQDGSP 748
Query: 783 YCQKFLE---------------EEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQ 827
Y + + EE E + ++ ++ +P Q L Y+
Sbjct: 749 YMRSMKQISKEKLKARRNRTAFEEVEEDLRLSLHLQDQDSVKDAVPDQQLDFKQLLARYK 808
Query: 828 KYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLL 887
S + M+ K+NL+LI LL ++ + GA+L+FLPGLA I+ LY+ L
Sbjct: 809 GVSKSVIKTMSIMDFEKVNLELIEALLEWI-VDGKHSYPPGAILVFLPGLAEIKMLYEQL 867
Query: 888 SNDRRF---YSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVF 944
++ F S R + LHS LS+++Q A F PP GV KI+++TNIAET ITI DVV+
Sbjct: 868 QSNSLFNNRRSNRCVIHPLHSSLSSEEQQAVFVKPPAGVTKIIISTNIAETSITIDDVVY 927
Query: 945 VIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERF-EGFM 1003
VID+G+ KE +Y S M SL +TFVS+A+ALQR+GRAGRV G CF ++T + +
Sbjct: 928 VIDSGKMKEKRYDASKGMESLEDTFVSQANALQRKGRAGRVASGVCFHLFTSHHYNHQLL 987
Query: 1004 DYSVPEILRVPLEELCLHIMKCNLGSP---EDFLSKALDPPQLQVISNAMNLLRKIGACE 1060
+PEI RVPLE+LCL I + S + S+ ++PP + + LR +GA
Sbjct: 988 KQQLPEIQRVPLEQLCLRIKILEMFSAHNLQSVFSRLIEPPHTDSLRASKIRLRDLGALT 1047
Query: 1061 LNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDE 1120
+E +LTPLG HLA+LPV+V+IGK+++FG+IF CLDP T+AA + KSPF +P +K+E
Sbjct: 1048 PDE-RLTPLGYHLASLPVDVRIGKLMLFGSIFRCLDPALTIAASLAFKSPFVSPWDKKEE 1106
Query: 1121 ADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQE 1180
A+ K A A+SD+L + AY GW+ + +E G R+ YCR+NFL+ L + +K++
Sbjct: 1107 ANQKKLEFAFANSDYLALLQAYKGWQLSTKE-GVRASYNYCRQNFLSGRVLQEMASLKRQ 1165
Query: 1181 LIKLVKAAGFSSSTTSTSWEGNRA------------SQTLSFQEIALLKAVLVAGLYDNV 1228
+L+ GF+ RA + + L+ A+L A LY NV
Sbjct: 1166 FTELLSDIGFAREGLRAREIEKRAQGGDGVLDATGEEANSNAENPKLISAMLCAALYPNV 1225
Query: 1229 GKI---------IYTKSVDVTEKLACI--VETAQGKAQVHPSSVNRDLQ--THGWLLYQE 1275
++ T +V + K A + V G +HPSSVN ++ +LLY E
Sbjct: 1226 VQVKSPEGKFQKTSTGAVRMQPKSAELKFVTKNDGYVHIHPSSVNYQVRHFDSPYLLYHE 1285
Query: 1276 KIRYARVYLRETTLITPFPVLLFGG---DIEVQHRERLLSI-DGWIYF-QAPVKIAVIFK 1330
KI+ +RV++R+ ++++ +P++LFGG ++++Q E ++S+ DGWI F A ++A + K
Sbjct: 1286 KIKTSRVFIRDCSMVSVYPLVLFGGGQVNVQLQRGEFVVSLDDGWIRFVAASHQVAELVK 1345
Query: 1331 QLRVLIDSVLRKKLENPKMSL----ENDKILQIITELIKTE 1367
+LR +D +L+ K++NP + L +I+ I +L+ T+
Sbjct: 1346 ELRCELDQLLQDKIKNPSIDLCTCPRGSRIISTIVKLVTTQ 1386
>gi|167830436 DEAH (Asp-Glu-Ala-His) box polypeptide 36 isoform 2
[Homo sapiens]
Length = 994
Score = 556 bits (1433), Expect = e-158
Identities = 344/886 (38%), Positives = 519/886 (58%), Gaps = 62/886 (6%)
Query: 497 NKLKQQQQQ--QQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNLFR 554
NKL Q+++ Q+ + N + E L+ + + +L+ +EDL+ +N R
Sbjct: 138 NKLDIQEKKLINQEKKMFRIRNRSYIDRDSEYLLQENEPDG-TLDQKLLEDLQKKKNDLR 196
Query: 555 KLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLL 614
Y ++ R++LP + + +V + H+V V++GETG GK+TQV F+L++ +
Sbjct: 197 -------YIEMQHFREKLPSYGMQKELVNLIDNHQVTVISGETGCGKTTQVTQFILDNYI 249
Query: 615 LNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACEST- 673
+ S C IVCTQPRRISA+S+A RV E G G GYQIR++SR
Sbjct: 250 -ERGKGSACRIVCTQPRRISAISVAERVAAERAESCGSGNST---GYQIRLQSRLPRKQG 305
Query: 674 RLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILM 733
+LYCTTG++L+ LQ D LS+VSH+++DE+HER++QSD L+ ++K++L RSDL +ILM
Sbjct: 306 SILYCTTGIILQWLQSDPYLSSVSHIVLDEIHERNLQSDVLMTVVKDLLNFRSDLKVILM 365
Query: 734 SATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEE 793
SAT+++EKFS YF +CP++ I G ++PV + LED+IE+ +V E+ E+ +F +
Sbjct: 366 SATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDVIEKIRYVPEQ-KEHRSQFKRGFMQ 424
Query: 794 VTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILEL 853
+N K Y+E P + ++YS+ T I M K++L+LI+ L
Sbjct: 425 GHVNRQEKEEKEAIYKERWPDY------VRELRRRYSASTVDVIEMMEDDKVDLNLIVAL 478
Query: 854 LAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQA 913
+ Y+ + +GA+L+FLPG +I L+DLL + F S +Q
Sbjct: 479 IRYIVLEEE----DGAILVFLPGWDNISTLHDLLMSQVMFKSV--------------NQT 520
Query: 914 AAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKA 973
F PPGVRKIV+ATNIAET ITI DVV+VID G+ KE + + +S++ +VSKA
Sbjct: 521 QVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNISTMSAEWVSKA 580
Query: 974 SALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDF 1033
+A QR+GRAGRV+ G C+ +Y R DY +PEILR PLEELCL I LG F
Sbjct: 581 NAKQRKGRAGRVQPGHCYHLYNGLRASLLDDYQLPEILRTPLEELCLQIKILRLGGIAYF 640
Query: 1034 LSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFG 1093
LS+ +DPP + + ++ L ++ A + E +LTPLG HLA LPV IGKM++FGA+F
Sbjct: 641 LSRLMDPPSNEAVLLSIRHLMELNALDKQE-ELTPLGVHLARLPVEPHIGKMILFGALFC 699
Query: 1094 CLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAM-ADSDHLTIYNAYLGWKKARQEG 1152
CLDPV T+AA ++ K PF P+G++ AD + LA SDHLT+ NA+ GW++AR+
Sbjct: 700 CLDPVLTIAASLSFKDPFVIPLGKEKIADARRKELAKDTRSDHLTVVNAFEGWEEARRR- 758
Query: 1153 GYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQE 1212
G+R E YC FL+ +L L ++K + + + AGF SS E N ++
Sbjct: 759 GFRYEKDYCWEYFLSSNTLQMLHNMKGQFAEHLLGAGFVSSRNPKDPESN-----INSDN 813
Query: 1213 IALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQT---HG 1269
++KAV+ AGLY V KI ++ K+ + G VHP SVN + QT +
Sbjct: 814 EKIIKAVICAGLYPKVAKI--RLNLGKKRKMVKVYTKTDGLVAVHPKSVNVE-QTDFHYN 870
Query: 1270 WLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQ--HRERLLSIDGWIYFQAPVKIAV 1327
WL+Y K+R + +YL + T ++P+ +L FGGDI +Q + + +++D WI FQ+P +IA
Sbjct: 871 WLIYHLKMRTSSIYLYDCTEVSPYCLLFFGGDISIQKDNDQETIAVDEWIVFQSPARIAH 930
Query: 1328 IFKQLRVLIDSVLRKKLENPKMSLEND------KILQIITELIKTE 1367
+ K+LR +D +L++K+E+P ND +L I +LIKT+
Sbjct: 931 LVKELRKELDILLQEKIESPHPVDWNDTKSRDCAVLSAIIDLIKTQ 976
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 450 bits (1158), Expect = e-126
Identities = 302/900 (33%), Positives = 469/900 (52%), Gaps = 65/900 (7%)
Query: 477 EELNKMETNKPRDLFIAKLLN--KLKQQQQQQQQHSENKRENSEDPEESWENLVSDE-DF 533
+ELN P D + LN KL Q + Q+Q+ S P+ +W S D
Sbjct: 291 QELNLEILPPPEDPSVPVALNIGKLAQFEPSQRQNQVGVVPWSP-PQSNWNPWTSSNIDE 349
Query: 534 SALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVV 593
L+ + ++ L +L+ Q +L+ER+ LPV K I+E + ++ VV++
Sbjct: 350 GPLAFATPEQISMDLKNELMYQLEQDHDLQAILQERELLPVKKFESEILEAISQNSVVII 409
Query: 594 AGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPG 653
G TG GK+TQVP F+L+D + N+ A++CNIV TQPRRISAVS+A RV E G E G
Sbjct: 410 RGATGCGKTTQVPQFILDDFIQND-RAAECNIVVTQPRRISAVSVAERVAFERGEEPGKS 468
Query: 654 GRNSLCGYQIRMESRACES-TRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSD 712
CGY +R ES +++CT GVLLRKL+ + +SHVIVDE+HER + +D
Sbjct: 469 -----CGYSVRFESILPRPHASIMFCTVGVLLRKLEAG--IRGISHVIVDEIHERDINTD 521
Query: 713 FLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEE 772
FLL++L++++Q ++ ++LMSAT+D+ F YF +CPI+ + GR+YPV+ + LED I+
Sbjct: 522 FLLVVLRDVVQAYPEVRIVLMSATIDTSMFCEYFFNCPIIEVYGRTYPVQEYFLEDCIQM 581
Query: 773 TGFV-LEKDSEYCQKFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSS 831
T FV KD + K + E+ N G +Y
Sbjct: 582 THFVPPPKDKKKKDKDDDGGEDDDANCNLICG-----------------------DEYGP 618
Query: 832 RTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDR 891
T+ ++ +N + +LI LL Y++ N+ GAVL+FLPG I + L +
Sbjct: 619 ETRLSMSQLNEKETPFELIEALLKYIET----LNVPGAVLVFLPGWNLIYTMQKHLEMNP 674
Query: 892 RFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRT 951
F S RY+++ LHS + ++Q F P GV K++L+TNIAET ITI DVV+VID+ +
Sbjct: 675 HFGSHRYQILPLHSQIPREEQRKVFDPVPVGVTKVILSTNIAETSITINDVVYVIDSCKQ 734
Query: 952 KENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEIL 1011
K + + M++ + SK + QR+GRAGRVR GFCF + +R RFE + PE+
Sbjct: 735 KVKLFTAHNNMTNYATVWASKTNLEQRKGRAGRVRPGFCFHLCSRARFERLETHMTPEMF 794
Query: 1012 RVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQ 1071
R PL E+ L I LG FL+KA++PP L + A + LR++ A + N+ +LTPLG+
Sbjct: 795 RTPLHEIALSIKLLRLGGIGQFLAKAIEPPPLDAVIEAEHTLRELDALDAND-ELTPLGR 853
Query: 1072 HLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMA 1131
LA LP+ + GKM+I G IF D + T+AA PF K + ++
Sbjct: 854 ILAKLPIEPRFGKMMIMGCIFYVGDAICTIAAATCFPEPFINE--GKRLGYIHRNFAGNR 911
Query: 1132 DSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFS 1191
SDH+ + + + W AR GG +EI +C LN +L + K +L +++ +GF
Sbjct: 912 FSDHVALLSVFQAWDDARM-GGEEAEIRFCEHKRLNMATLRMTWEAKVQLKEILINSGFP 970
Query: 1192 SSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQ 1251
T N + ++ ++L G+Y NV Y K EK I+ T
Sbjct: 971 EDCLLTQVFTNTGPD----NNLDVVISLLAFGVYPNV---CYHK-----EKRK-ILTTEG 1017
Query: 1252 GKAQVHPSSVNRDLQTHG------WLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQ 1305
A +H SSVN + + ++ EKIR + + TL+TP +LLF +VQ
Sbjct: 1018 RNALIHKSSVNCPFSSQDMKYPSPFFVFGEKIRTRAISAKGMTLVTPLQLLLFASK-KVQ 1076
Query: 1306 HRERLLSIDGWIYFQAPVKIAVIFKQLRVLIDSVLRKKLENPKMSLENDKILQIITELIK 1365
+++ +D WI Q + A LR +++++ + + P + + D + + + +I+
Sbjct: 1077 SDGQIVLVDDWIKLQISHEAAACITGLRAAMEALVVEVTKQPAIISQLDPVNERMLNMIR 1136
>gi|20336290 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 2 [Homo
sapiens]
Length = 1155
Score = 424 bits (1091), Expect = e-118
Identities = 281/827 (33%), Positives = 441/827 (53%), Gaps = 103/827 (12%)
Query: 567 KERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIV 626
+E QLPV HRD+I+ +++H VVV++G+TG GK+T++P LLE + E ++CN++
Sbjct: 390 QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYV-TEGRGARCNVI 448
Query: 627 CTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRA-CESTRLLYCTTGVLLR 685
TQPRRISAVS+A RV ELG P R ++ G+Q+R+ES+ LL+CT G+LLR
Sbjct: 449 ITQPRRISAVSVAQRVSHELG----PSLRRNV-GFQVRLESKPPSRGGALLFCTVGILLR 503
Query: 686 KLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTY 745
KLQ + L VSHVIVDEVHER V +DFLLI+LK + + L L+LMSAT D+E+FS Y
Sbjct: 504 KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRY 563
Query: 746 FTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGI 805
F CP++++ G YPV+ +LEDI+ + G +Y + E E
Sbjct: 564 FGGCPVIKVPGFMYPVKEHYLEDILAKLG-----KHQYLHRHRHHESE------------ 606
Query: 806 KKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRN 865
+ ++LDL+ +L+ ++D R
Sbjct: 607 -----------------------------------DECALDLDLVTDLVLHIDA----RG 627
Query: 866 IEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRK 925
G +L FLPG I+ + L + +Y ++ +HS + DQ A F PP GVRK
Sbjct: 628 EPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRK 687
Query: 926 IVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRV 985
IVLATNIAET ITI D+V V+D+G KE +Y +++S L +VS+A+ +QR+GRAGR
Sbjct: 688 IVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRC 747
Query: 986 RDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPE----DFLSKALDPP 1041
+ GF + ++ R R E + + VPEILR PLE L +++ + PE +FLSKA+D P
Sbjct: 748 QSGFAYHLFPRSRLEKMVPFQVPEILRTPLENL---VLQAKIHMPEKTAVEFLSKAVDSP 804
Query: 1042 QLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATL 1101
++ + A+ LL++IG + E LT LGQ LA + + ++ K ++ AIF CL P+ +
Sbjct: 805 NIKAVDEAVILLQEIGVLDQRE-YLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVV 863
Query: 1102 AAVMTEKSPFTTPIGRKDEADLAKSALAM-ADSDHLTIYNAYLGWKKARQEGGYRSEITY 1160
+ +T + PF++ + + E D K+ L+ + SDHL A GW++ + S Y
Sbjct: 864 VSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENY 922
Query: 1161 CRRNFLNRTSLLTLEDVKQELIKLVKAA---GFSSSTTSTSWEGNRASQTLSFQEIALLK 1217
N L SL + + ++ + + A G S T S + N S +E L+K
Sbjct: 923 LEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYS-----EEEELVK 977
Query: 1218 AVLVAGLYDNVGKIIYTKSVDVTEK-----LACIVETAQGKAQVHPSSVNRDLQ--THGW 1270
VL+AGLY N +I + VT + + T G +H S++NR+ W
Sbjct: 978 GVLMAGLYPN---LIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRW 1034
Query: 1271 LLYQEKIR-YARVYLRETTLITPFPVLLF-GGDIEVQHRER----LLSIDGWIYFQAPVK 1324
L Y ++ V++R+++ + P VLL GD+ ++ R LS + + +
Sbjct: 1035 LTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSR 1094
Query: 1325 IAVIFKQLRVLIDSVLRKKLEN------PKMSLENDKILQIITELIK 1365
+ K+LR + ++ + L + P + E+ ++L ++ EL++
Sbjct: 1095 TVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLR 1141
>gi|20336294 DEAH (Asp-Glu-Ala-His) box polypeptide 30 isoform 1 [Homo
sapiens]
Length = 1194
Score = 424 bits (1091), Expect = e-118
Identities = 281/827 (33%), Positives = 441/827 (53%), Gaps = 103/827 (12%)
Query: 567 KERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIV 626
+E QLPV HRD+I+ +++H VVV++G+TG GK+T++P LLE + E ++CN++
Sbjct: 429 QEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYV-TEGRGARCNVI 487
Query: 627 CTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRA-CESTRLLYCTTGVLLR 685
TQPRRISAVS+A RV ELG P R ++ G+Q+R+ES+ LL+CT G+LLR
Sbjct: 488 ITQPRRISAVSVAQRVSHELG----PSLRRNV-GFQVRLESKPPSRGGALLFCTVGILLR 542
Query: 686 KLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTY 745
KLQ + L VSHVIVDEVHER V +DFLLI+LK + + L L+LMSAT D+E+FS Y
Sbjct: 543 KLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRY 602
Query: 746 FTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGI 805
F CP++++ G YPV+ +LEDI+ + G +Y + E E
Sbjct: 603 FGGCPVIKVPGFMYPVKEHYLEDILAKLG-----KHQYLHRHRHHESE------------ 645
Query: 806 KKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRN 865
+ ++LDL+ +L+ ++D R
Sbjct: 646 -----------------------------------DECALDLDLVTDLVLHIDA----RG 666
Query: 866 IEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRK 925
G +L FLPG I+ + L + +Y ++ +HS + DQ A F PP GVRK
Sbjct: 667 EPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRK 726
Query: 926 IVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRV 985
IVLATNIAET ITI D+V V+D+G KE +Y +++S L +VS+A+ +QR+GRAGR
Sbjct: 727 IVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRC 786
Query: 986 RDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPE----DFLSKALDPP 1041
+ GF + ++ R R E + + VPEILR PLE L +++ + PE +FLSKA+D P
Sbjct: 787 QSGFAYHLFPRSRLEKMVPFQVPEILRTPLENL---VLQAKIHMPEKTAVEFLSKAVDSP 843
Query: 1042 QLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATL 1101
++ + A+ LL++IG + E LT LGQ LA + + ++ K ++ AIF CL P+ +
Sbjct: 844 NIKAVDEAVILLQEIGVLDQRE-YLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVV 902
Query: 1102 AAVMTEKSPFTTPIGRKDEADLAKSALAM-ADSDHLTIYNAYLGWKKARQEGGYRSEITY 1160
+ +T + PF++ + + E D K+ L+ + SDHL A GW++ + S Y
Sbjct: 903 VSCLT-RDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENY 961
Query: 1161 CRRNFLNRTSLLTLEDVKQELIKLVKAA---GFSSSTTSTSWEGNRASQTLSFQEIALLK 1217
N L SL + + ++ + + A G S T S + N S +E L+K
Sbjct: 962 LEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYS-----EEEELVK 1016
Query: 1218 AVLVAGLYDNVGKIIYTKSVDVTEK-----LACIVETAQGKAQVHPSSVNRDLQ--THGW 1270
VL+AGLY N +I + VT + + T G +H S++NR+ W
Sbjct: 1017 GVLMAGLYPN---LIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRW 1073
Query: 1271 LLYQEKIR-YARVYLRETTLITPFPVLLF-GGDIEVQHRER----LLSIDGWIYFQAPVK 1324
L Y ++ V++R+++ + P VLL GD+ ++ R LS + + +
Sbjct: 1074 LTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSR 1133
Query: 1325 IAVIFKQLRVLIDSVLRKKLEN------PKMSLENDKILQIITELIK 1365
+ K+LR + ++ + L + P + E+ ++L ++ EL++
Sbjct: 1134 TVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLR 1180
>gi|166851804 tudor domain containing 9 [Homo sapiens]
Length = 1382
Score = 304 bits (778), Expect = 4e-82
Identities = 209/683 (30%), Positives = 352/683 (51%), Gaps = 90/683 (13%)
Query: 572 LPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPR 631
LP+ ++++ +V ++ + VV++ G TGSGKSTQ+P ++L+ + ++ C+IV TQPR
Sbjct: 132 LPISRYKEEVVSLIESNSVVIIHGATGSGKSTQLPQYILDHYVQR---SAYCSIVVTQPR 188
Query: 632 RISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDG 691
+I A S+A + E G + GYQ+ +E A E TRL+Y TTGVLL+K+
Sbjct: 189 KIGASSIARWISKERAWTLG-----GVVGYQVGLEKIATEDTRLIYMTTGVLLQKIVSAK 243
Query: 692 LLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSD-LHLILMSATVDSEKFSTYFT--- 747
L +H+I+DEVHER+ + DFLL++++++L+ S + ++LMSAT+ ++F+ YF
Sbjct: 244 SLMEFTHIIIDEVHERTEEMDFLLLVVRKLLRTNSRFVKVVLMSATISCKEFADYFAVPV 303
Query: 748 -----HCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKA 802
I + G+ + VE ++L D+ L L EE +T ++ A
Sbjct: 304 QNKMNPAYIFEVEGKPHSVEEYYLNDLEHIHHSKLSPH-------LLEEPVITKDIYEVA 356
Query: 803 GGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQ 862
+ +Q D+ K S Q +LE
Sbjct: 357 VSL--------IQMFDDLDMKESGNKAWSGAQ--------------FVLE---------- 384
Query: 863 FRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPG 922
+VL+FLPGL I +++LL++ +R +V LHS ++ ++Q F P PG
Sbjct: 385 ----RSSVLVFLPGLGEINYMHELLTS---LVHKRLQVYPLHSSVALEEQNNVFLSPVPG 437
Query: 923 VRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRA 982
RKI+L+TNIAE+ +T+PDV +VID T+ E + SL ++ SK S QR+GRA
Sbjct: 438 YRKIILSTNIAESSVTVPDVKYVIDFCLTRTLVCDEDTNYQSLRLSWASKTSCNQRKGRA 497
Query: 983 GRVRDGFCFRMYTRERFEGFM-DYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPP 1041
GRV G+C+R+ ++ ++ + D+ VPE+LR PL L + ++G P L+ AL PP
Sbjct: 498 GRVSRGYCYRLVHKDFWDNSIPDHVVPEMLRCPLGSTILKVKLLDMGEPRALLATALSPP 557
Query: 1042 QLQVISNAMNLLRKIGACEL---------NEPKLTPLGQHLAALPVNVKIGKMLIFGAIF 1092
L I + LL+++GA + ++ +LT LG+ LA LPVN ++GK+++ G +F
Sbjct: 558 GLSDIERTILLLKEVGALAVSGQREDENPHDGELTFLGRVLAQLPVNQQLGKLIVLGHVF 617
Query: 1093 GCLDPVATLAAVMTEKSPFTTPI-----GRKDEADLAKSALAMADSDHLTIYNAYLGWKK 1147
GCLD +AA ++ K+ F P G +++ + + S + SD + + A+ WK
Sbjct: 618 GCLDECLIIAAALSLKNFFAMPFRQHLDGYRNKVNFSGS----SKSDCIALVEAFKTWKA 673
Query: 1148 ARQEGGYR---SEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRA 1204
RQ G R E+ + R N++ + + ++ +EL + + +
Sbjct: 674 CRQTGELRYPKDELNWGRLNYIQIKRIREVAELYEELKTRISQFNMHVDSRRPVMD---- 729
Query: 1205 SQTLSFQEIALLKAVLVAGLYDN 1227
Q +++ +L+ VL Y N
Sbjct: 730 -QEYIYKQRFILQVVLAGAFYPN 751
>gi|38505213 YTH domain containing 2 [Homo sapiens]
Length = 1430
Score = 288 bits (736), Expect = 3e-77
Identities = 197/581 (33%), Positives = 306/581 (52%), Gaps = 77/581 (13%)
Query: 844 KINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYD-LLSNDRRFY--SERYKV 900
K++LDLI+ LL + S GAVLIFLPG I L D +L +D+RF + RY+V
Sbjct: 603 KVDLDLIMHLLYNICHSCD----AGAVLIFLPGYDEIVGLRDRILFDDKRFADNTHRYQV 658
Query: 901 IALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESS 960
LHS + T DQ PP GVRKI+L+TNIAET IT+ DVVFVID+G+ KE + +
Sbjct: 659 FMLHSNMQTSDQKKVLKNPPAGVRKIILSTNIAETSITVNDVVFVIDSGKVKEKSFDALN 718
Query: 961 QMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCL 1020
++ L ++SKASA+QR+GRAGR R G CFR+++R RF+ +++ PE+LR+PL+ELCL
Sbjct: 719 FVTMLKMVWISKASAIQRKGRAGRCRPGICFRLFSRLRFQNMLEFQTPELLRMPLQELCL 778
Query: 1021 HI-MKCNLGSP-EDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPV 1078
H + + P DFL KA +PP ++ NA+ +L+ I A + E LT LG HLA LPV
Sbjct: 779 HTKLLAPVNCPIADFLMKAPEPPPALIVRNAVQMLKTIDAMDTWE-DLTELGYHLADLPV 837
Query: 1079 NVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTP--IGRKDEADLA-KSALAMADSDH 1135
+GKM++ + CLDP+ T+A + + PF P +K A L K A A SDH
Sbjct: 838 EPHLGKMVLCAVVLKCLDPILTIACTLAYRDPFVLPTQASQKRAAMLCRKRFTAGAFSDH 897
Query: 1136 LTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTT 1195
+ + A+ W+KAR +G R+ +C +NFL++ ++ + ++ +L+ ++A+GF +
Sbjct: 898 MALLRAFQAWQKARSDGWERA---FCEKNFLSQATMEIIIGMRTQLLGQLRASGFVRARG 954
Query: 1196 STSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQ 1255
G+ + + A++KA LVAG+Y N+ V V + + + K +
Sbjct: 955 G----GDIRDVNTNSENWAVVKAALVAGMYPNL--------VHVDRENLVLTGPKEKKVR 1002
Query: 1256 VHPSSVNRDLQ-----------------THGWLLYQEKIRYARV-YLRETTLITPFPVLL 1297
HP+SV Q WL+Y E R R+ +R + +TP +L+
Sbjct: 1003 FHPASVLSQPQYKKIPPANGQAAAIKALPTDWLIYDEMTRAHRIANIRCCSAVTPVTILV 1062
Query: 1298 FGG-------------------------DIEVQHRE----RLLSIDGWIYFQAPVKIAVI 1328
F G D E++ + L +D W++F + A +
Sbjct: 1063 FCGPARLASNALQEPSSFRVDGIPNDSSDSEMEDKTTANLAALKLDEWLHFTLEPEAASL 1122
Query: 1329 FKQLRVLIDSVLRKKLENPK--MSLENDKILQIITELIKTE 1367
QLR S+ +++ P S ++ ++ I ++ TE
Sbjct: 1123 LLQLRQKWHSLFLRRMRAPSKPWSQVDEATIRAIIAVLSTE 1163
Score = 193 bits (490), Expect = 1e-48
Identities = 107/228 (46%), Positives = 145/228 (63%), Gaps = 9/228 (3%)
Query: 569 RQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCT 628
RQ LPVF+ ++ IV+ +K ++VV++ GETGSGK+TQ+P FLL+D N C I CT
Sbjct: 190 RQSLPVFEKQEEIVKIIKENKVVLIVGETGSGKTTQIPQFLLDDCFKN---GIPCRIFCT 246
Query: 629 QPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQ 688
QPRR++A+++A RV E G GYQIR+ESR T L +CT GVLLR L
Sbjct: 247 QPRRLAAIAVAERVAAERRERIG-----QTIGYQIRLESRVSPKTLLTFCTNGVLLRTLM 301
Query: 689 E-DGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFT 747
D LS V+HVIVDEVHER SDFLL L+++LQK L LIL SA +D F YF
Sbjct: 302 AGDSTLSTVTHVIVDEVHERDRFSDFLLTKLRDLLQKHPTLKLILSSAALDVNLFIRYFG 361
Query: 748 HCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVT 795
CP++ I GR + V+ LEDI+ TG+ ++ +Y ++ +EE++ T
Sbjct: 362 SCPVIYIQGRPFEVKEMFLEDILRTTGYTNKEMLKYKKEKQQEEKQQT 409
>gi|17999539 DEAH (Asp-Glu-Ala-His) box polypeptide 38 [Homo sapiens]
Length = 1227
Score = 282 bits (721), Expect = 2e-75
Identities = 204/680 (30%), Positives = 337/680 (49%), Gaps = 102/680 (15%)
Query: 554 RKLQSTPKYQK---LLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLL 610
RK +++ ++ K +L++RQ LP+F + ++ ++ + +V+V GETGSGK+TQ+ +L
Sbjct: 511 RKSEASSEFAKKKSILEQRQYLPIFAVQQELLTIIRDNSIVIVVGETGSGKTTQLTQYLH 570
Query: 611 EDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRAC 670
ED + I CTQPRR++A+S+A RV +E+G G GY IR E
Sbjct: 571 EDGYTDYGM-----IGCTQPRRVAAMSVAKRVSEEMG-----GNLGEEVGYAIRFEDCTS 620
Query: 671 ESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHL 730
E+T + Y T G+LLR+ + L + S +I+DE HERS+ +D L +L+E++ +RSDL L
Sbjct: 621 ENTLIKYMTDGILLRESLREADLDHYSAIIMDEAHERSLNTDVLFGLLREVVARRSDLKL 680
Query: 731 ILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEE 790
I+ SAT+D+EKF+ +F + PI I GR++PV++ F +Y + +++
Sbjct: 681 IVTSATMDAEKFAAFFGNVPIFHIPGRTFPVDIL----------FSKTPQEDYVEAAVKQ 730
Query: 791 EEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLI 850
+V + +GA D+ F ++ D I
Sbjct: 731 SLQVHL-------------------SGAPGDILIFMPG-----------QEDIEVTSDQI 760
Query: 851 LELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQ 910
+E L L+ +P L LP +Y L +D
Sbjct: 761 VEHLEELENAP--------ALAVLP-------IYSQLPSDL------------------- 786
Query: 911 DQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFV 970
QA F P GVRK ++ATNIAET +T+ ++FVID+G K ++ M +L +
Sbjct: 787 -QAKIFQKAPDGVRKCIVATNIAETSLTVDGIMFVIDSGYCKLKVFNPRIGMDALQIYPI 845
Query: 971 SKASALQRQGRAGRVRDGFCFRMYTRERFEG-FMDYSVPEILRVPLEELCLHIMKCNLGS 1029
S+A+A QR GRAGR G CFR+YT+ ++ + +VPEI R L + L + +LG
Sbjct: 846 SQANANQRSGRAGRTGPGQCFRLYTQSAYKNELLTTTVPEIQRTNLANVVLLLK--SLGV 903
Query: 1030 PEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFG 1089
+ +DPP + N+M L +GA + N LT G+ + P++ + KMLI
Sbjct: 904 QDLLQFHFMDPPPEDNMLNSMYQLWILGALD-NTGGLTSTGRLMVEFPLDPALSKMLIVS 962
Query: 1090 AIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKAR 1149
GC + + ++++ + F P GR++E+D + A+ +SDHLT N YL WK
Sbjct: 963 CDMGCSSEILLIVSMLSVPAIFYRPKGREEESDQIREKFAVPESDHLTYLNVYLQWKNNN 1022
Query: 1150 QEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLS 1209
+C +F++ ++ + +V+ +L ++ S ++ T W+ R +
Sbjct: 1023 Y------STIWCNDHFIHAKAMRKVREVRAQLKDIMVQQRMSLASCGTDWDIVRKCICAA 1076
Query: 1210 -FQEIALLKAVLVAGLYDNV 1228
F + A LK + G Y N+
Sbjct: 1077 YFHQAAKLKGI---GEYVNI 1093
>gi|68509926 DEAH (Asp-Glu-Ala-His) box polypeptide 15 [Homo sapiens]
Length = 795
Score = 243 bits (621), Expect = 7e-64
Identities = 225/845 (26%), Positives = 361/845 (42%), Gaps = 144/845 (17%)
Query: 463 RDVWLEWSDAEKKREELNKMETNKPRD-LFIAKLLNKLKQQQQQQQQHSENKRENSEDPE 521
RD + D E++RE+ + E + + I+ L LK HS + ++
Sbjct: 40 RDRERDRGDREREREKEKEKELRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAH 99
Query: 522 ESWENLVSDEDFSALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSI 581
+ A L N F L TP+Y +LK+R QLPV++++D
Sbjct: 100 STHAG-------------HAGHTSLPQCINPFTNLPHTPRYYDILKKRLQLPVWEYKDRF 146
Query: 582 VETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANR 641
+ L RH+ V+ GETGSGK+TQ+P + +E + K + CTQPRR++A+S+A R
Sbjct: 147 TDILVRHQSFVLVGETGSGKTTQIPQWCVE--YMRSLPGPKRGVACTQPRRVAAMSVAQR 204
Query: 642 VCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIV 701
V DE+ G GY IR E + T L Y T G+LLR+ D LL +I+
Sbjct: 205 VADEMDVMLGQE-----VGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIIL 259
Query: 702 DEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPV 761
DE HER++ +D L+ +LKE++++RSDL +I+MSAT+D+ KF YF +CP+L I GR++PV
Sbjct: 260 DEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPV 319
Query: 762 EVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTI--------NVTSKAGGIKKYQEYIP 813
E+F+ + E ++ Q + EEEE + + IK+ + +
Sbjct: 320 EIFYTPE--PERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLG 377
Query: 814 VQTGAHADLNPFYQKYSSRTQHAILY-MNPHKINLDLILELLAYLDKSPQFRNIEGAVLI 872
+ G + P Y + Q I P K N + +++ + + I+G V +
Sbjct: 378 PEVG-DIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFV 436
Query: 873 FLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNI 932
PG A ++ Y+ R +V S+L T + K
Sbjct: 437 IDPGFA-----------KQKVYNPRIRV---ESLLVT------------AISKASAQQRA 470
Query: 933 AETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFR 992
G T P F + T E Y Q ++ E S ++ Q + + D F
Sbjct: 471 GRAGRTRPGKCFRLYT----EKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHF- 525
Query: 993 MYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNL 1052
FMD PE L A+ L
Sbjct: 526 --------DFMDPPAPETL-----------------------------------MRALEL 542
Query: 1053 LRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFT 1112
L + A ++ LT LG +A P++ ++ KM+I + C + V ++ A+++ F
Sbjct: 543 LNYLAALN-DDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFV 601
Query: 1113 TPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLL 1172
P K AD AK A D DHLT+ N Y +K+ + + +C NF+N SL+
Sbjct: 602 RPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHE------SVQWCYDNFINYRSLM 655
Query: 1173 TLEDVKQELIKLVKAAGF---SSSTTSTSWEGN--RASQTLSFQEIALLKAVLVAGLYDN 1227
+ ++V+Q+L +++ S+ TS + N +A T F ++A L +
Sbjct: 656 SADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHL---------ER 706
Query: 1228 VGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRET 1287
G + K V Q+HPS+V W+LY E + + Y+R
Sbjct: 707 TGHYLTVKDNQV--------------VQLHPSTVLD--HKPEWVLYNEFVLTTKNYIRTC 750
Query: 1288 TLITP 1292
T I P
Sbjct: 751 TDIKP 755
>gi|20336302 DEAH (Asp-Glu-Ala-His) box polypeptide 33 [Homo sapiens]
Length = 707
Score = 243 bits (620), Expect = 9e-64
Identities = 185/633 (29%), Positives = 298/633 (47%), Gaps = 102/633 (16%)
Query: 558 STPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNE 617
++P + + +R+ LP+F+ R ++ L+ V+ GETGSGK+TQ+P +L E + +
Sbjct: 60 ASPYPEAVELQRRSLPIFQARGQLLAQLRNLDNAVLIGETGSGKTTQIPQYLYEGGISRQ 119
Query: 618 WEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLY 677
I TQPRR++A+SLA RV DE E G L GY +R + E TR+ +
Sbjct: 120 GI-----IAVTQPRRVAAISLATRVSDEKRTELG-----KLVGYTVRFDDVTSEDTRIKF 169
Query: 678 CTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSD-----LHLIL 732
T G+LLR+ D LL S VI+DE HER++ +D L ++K ++R + L +I+
Sbjct: 170 LTDGMLLREAISDSLLRKYSCVILDEAHERTIHTDVLFGVVKAAQKRRKELGKLPLKVIV 229
Query: 733 MSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEE 792
MSAT+D + FS YF P+L + GR +P++VF+ + + ++Y L
Sbjct: 230 MSATMDVDLFSQYFNGAPVLYLEGRQHPIQVFYTK----------QPQNDYLHAALVSVF 279
Query: 793 EVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILE 852
++ S Q+ + TG + S+T I P L+L
Sbjct: 280 QIHQEAPSS-------QDILVFLTGQEE------IEAMSKTCRDIAKHLPDGCPAMLVLP 326
Query: 853 LLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQ 912
L A L + Q R +GA + Y+ + I+ST
Sbjct: 327 LYASLPYAQQLRVFQGA-------------------------PKGYRKV----IISTN-- 355
Query: 913 AAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSK 972
+ T+I TGI +V+DTG K KY+ S + L VSK
Sbjct: 356 --------------IAETSITITGIK-----YVVDTGMVKAKKYNPDSGLEVLAVQRVSK 396
Query: 973 ASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGS--P 1030
A QR GRAGR G C+R+YT + FE F +VPEI R L + L ++ + +
Sbjct: 397 TQAWQRTGRAGREDSGICYRLYTEDEFEKFDKMTVPEIQRCNLASVMLQLLAMKVPNVLT 456
Query: 1031 EDFLSKALDPPQLQVISNAMNLLRKIGACELNEPK--LTPLGQHLAALPVNVKIGKMLIF 1088
DF+SK P I A+ L +GA E + + LTP+G+ +AA P+ K K ++
Sbjct: 457 FDFMSK----PSPDHIQAAIAQLDLLGALEHKDDQLTLTPMGRKMAAFPLEPKFAKTILM 512
Query: 1089 GAIFGCLDPVATLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKA 1148
F C + + T+ ++++ S P R++E + ++ DH+T+ N Y +K
Sbjct: 513 SPKFHCTEEILTIVSLLSVDSVLHNPPSRREEVQGVRKKFISSEGDHMTLLNIYRTFKNL 572
Query: 1149 RQEGGYRSEITYCRRNFLNRTSLLTLEDVKQEL 1181
GG + +C+ NF+N ++ + +V+ +L
Sbjct: 573 ---GGNKD---WCKENFVNSKNMTLVAEVRAQL 599
>gi|31542729 DEAH (Asp-Glu-Ala-His) box polypeptide 40 [Homo sapiens]
Length = 779
Score = 228 bits (581), Expect = 3e-59
Identities = 193/722 (26%), Positives = 338/722 (46%), Gaps = 102/722 (14%)
Query: 573 PVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRR 632
P+ K R I++ ++ + ++V G TGSGK+TQ+P +L E + I TQPR+
Sbjct: 54 PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGF-----SQHGMIGVTQPRK 108
Query: 633 ISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDGL 692
++A+S+A RV +E+ C G S GYQ+R + + + T + Y T G LL+ + D
Sbjct: 109 VAAISVAQRVAEEMKCTLG-----SKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPN 163
Query: 693 LSNVSHVIVDEVHERSVQSDFLLIILKEILQKRS-----DLHLILMSATVDSEKFSTYFT 747
L+ S +I+DE HER++ +D L +LK++ Q++S L +++MSAT++ K S +F
Sbjct: 164 LTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFG 223
Query: 748 HCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGIKK 807
+CPI I GR YPV E G +++ Y Q +E ++ +N AG I
Sbjct: 224 NCPIFDIPGRLYPVR----EKFCNLIGPRDRENTAYIQAIVEVTMDIHLN--EMAGDI-- 275
Query: 808 YQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIE 867
+ TG ++ +L+ ++ D Q ++
Sbjct: 276 ----LVFLTG----------QFEIEKSCELLFQMAESVDYDY----------DVQDTTLD 311
Query: 868 GAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIV 927
G L+ LP Y ++ D+ Q F PPPG+RK V
Sbjct: 312 G--LLILP-------CYGSMTTDQ--------------------QRRIFLPPPPGIRKCV 342
Query: 928 LATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRD 987
++TNI+ T +TI + +V+D G K+ ++ + L +SK+ ALQR GRAGR
Sbjct: 343 ISTNISATSLTIDGIRYVVDGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRTSS 402
Query: 988 GFCFRMYTRERFEGFM-DYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVI 1046
G CFR+Y+++ + M D+ +PEI R L + L +KC L + LDPP ++I
Sbjct: 403 GKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVL-TLKC-LAIHDVIRFPYLDPPNERLI 460
Query: 1047 SNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMT 1106
A+ L + A + +T LG + P+ + +I A C D + +AA+++
Sbjct: 461 LEALKQLYQCDAID-RSGHVTRLGLSMVEFPLPPHLTCAVIKAASLDCEDLLLPIAAMLS 519
Query: 1107 EKSPFTTPIG--RKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRN 1164
++ F P+ + EA+ LA + +++ + G + ++C+++
Sbjct: 520 VENVFIRPVDPEYQKEAEQRHRELAAKAGGFNDFATLAVIFEQCKSSG---APASWCQKH 576
Query: 1165 FLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGL 1224
+++ L + V+ +L +L++ S ++EG + +L+ L AG
Sbjct: 577 WIHWRCLFSAFRVEAQLRELIRKLKQQSDFPKETFEGPKHE---------VLRRCLCAGY 627
Query: 1225 YDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTH-GWLLYQEKIRYARVY 1283
+ NV + +SV T C V+ +HPSS + +T W+++ E + +VY
Sbjct: 628 FKNVAR----RSVGRT---FCTVDGRGSPVHIHPSSALHEQETKLEWIIFHEVLVTTKVY 680
Query: 1284 LR 1285
R
Sbjct: 681 AR 682
>gi|38158022 DEAH (Asp-Glu-Ala-His) box polypeptide 34 [Homo sapiens]
Length = 1143
Score = 219 bits (557), Expect = 2e-56
Identities = 121/322 (37%), Positives = 188/322 (58%), Gaps = 5/322 (1%)
Query: 868 GAVLIFLPGLAHIQQLYDLLSNDRRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRKIV 927
G +L+FL G+A I + + + +++R+ V+ LHS LS DQ F + PPGVRK +
Sbjct: 379 GDLLVFLSGMAEISAVLEA-AQTYASHTQRWVVLPLHSALSVADQDKVFDVAPPGVRKCI 437
Query: 928 LATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRD 987
L+TNIAET +TI + FV+D+G+ KE Y +++ L E ++S+ASA QR+GRAGR
Sbjct: 438 LSTNIAETSVTIDGIRFVVDSGKVKEMSYDPQAKLQRLQEFWISQASAEQRKGRAGRTGP 497
Query: 988 GFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVIS 1047
G CFR+Y ++ F Y VPEI RV L+ L L + ++G P F ++PP +
Sbjct: 498 GVCFRLYAESDYDAFAPYPVPEIRRVALDSLVLQMKSMSVGDPRTF--PFIEPPPPASLE 555
Query: 1048 NAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTE 1107
A+ LR GA + +E LTP+G LA LPV+V IGKMLI G++F ++PV T+AA ++
Sbjct: 556 TAILYLRDQGALDSSE-ALTPIGSLLAQLPVDVVIGKMLILGSMFSLVEPVLTIAAALSV 614
Query: 1108 KSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLN 1167
+SPFT E A+ L D T++N + W + + E R+ +CRR +
Sbjct: 615 QSPFTRSAQSSPECAAARRPLESDQGDPFTLFNVFNAWVQVKSERS-RNSRKWCRRRGIE 673
Query: 1168 RTSLLTLEDVKQELIKLVKAAG 1189
L + +++++ +L++ G
Sbjct: 674 EHRLYEMANLRRQFKELLEDHG 695
Score = 173 bits (438), Expect = 1e-42
Identities = 97/227 (42%), Positives = 143/227 (62%), Gaps = 13/227 (5%)
Query: 553 FRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLED 612
F + Q+ + KL +ER LP+ ++ + I++TLK H+VVVVAG+TG GKSTQVP +LL
Sbjct: 143 FGQKQAFGRLAKLQRERAALPIAQYGNRILQTLKEHQVVVVAGDTGCGKSTQVPQYLLA- 201
Query: 613 LLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACES 672
A ++ CTQPRRI+ +SLA RV E + G S GYQIR ES +
Sbjct: 202 -------AGFSHVACTQPRRIACISLAKRVGFESLSQYG-----SQVGYQIRFESTRSAA 249
Query: 673 TRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLIL 732
T++++ T G+LLR++Q + L +IVDEVHER + +DFLL +L+ +L R DL +IL
Sbjct: 250 TKIVFLTVGLLLRQIQREPSLPQYEVLIVDEVHERHLHNDFLLGVLQRLLPTRPDLKVIL 309
Query: 733 MSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEK 779
MSAT++ FS+YF++ P++++ GR +P+ V + E T EK
Sbjct: 310 MSATINISLFSSYFSNAPVVQVPGRLFPITVVYQPQEAEPTTSKSEK 356
>gi|4826690 DEAH (Asp-Glu-Ala-His) box polypeptide 8 [Homo sapiens]
Length = 1220
Score = 175 bits (443), Expect = 3e-43
Identities = 142/533 (26%), Positives = 243/533 (45%), Gaps = 60/533 (11%)
Query: 781 SEYCQKFLEEEEEVTINVTSKAGGIKKY----QEYIPVQTGAHADLNPFYQKY------- 829
++Y L+E E TI+ G +KK Q+ + T A D F Q +
Sbjct: 677 TQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQYFYEAPIFT 736
Query: 830 -SSRTQHA-ILYMNPHK---INLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLY 884
RT ILY + ++ LI + +L + P G +L+FL G I
Sbjct: 737 IPGRTYPVEILYTKEPETDYLDASLITVMQIHLTEPP------GDILVFLTGQEEIDTAC 790
Query: 885 DLLSNDRRFYSERYK---VIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPD 941
++L + ++ ++S L ++ Q F PPG RK+V+ATNIAET +TI
Sbjct: 791 EILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAPPGSRKVVIATNIAETSLTIDG 850
Query: 942 VVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERF-E 1000
+ +V+D G K+ Y+ + + LV T +S+A A QR GRAGR G C+R+YT + +
Sbjct: 851 IYYVVDPGFVKQKVYNSKTGIDQLVVTPISQAQAKQRAGRAGRTGPGKCYRLYTERAYRD 910
Query: 1001 GFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLS-KALDPPQLQVISNAMNLLRKIGAC 1059
+ +VPEI R L L + + D LS +D P ++ + AM L +GA
Sbjct: 911 EMLTTNVPEIQRTNLASTVLSLKAMGI---NDLLSFDFMDAPPMETLITAMEQLYTLGAL 967
Query: 1060 ELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPFTTPIGRKD 1119
+ +E LT LG+ +A P+ + KMLI GC + + T+ ++++ ++ F P ++
Sbjct: 968 D-DEGLLTRLGRRMAEFPLEPMLCKMLIMSVHLGCSEEMLTIVSMLSVQNVFYRPKDKQA 1026
Query: 1120 EADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQ 1179
AD K+ + DHLT+ Y WK + +C NF+ SL +D+++
Sbjct: 1027 LADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSN------PWCYENFIQARSLRRAQDIRK 1080
Query: 1180 ELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDV 1239
+++ ++ + ++ + ++ + +G + N K D
Sbjct: 1081 QMLGIM--------------DRHKLDVVSCGKSTVRVQKAICSGFFRNAAK------KDP 1120
Query: 1240 TEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLRETTLITP 1292
E +++ Q +HPSS + Q W++Y E + + Y+RE T I P
Sbjct: 1121 QEGYRTLID--QQVVYIHPSSALFNRQPE-WVVYHELVLTTKEYMREVTTIDP 1170
Score = 158 bits (399), Expect = 4e-38
Identities = 82/204 (40%), Positives = 130/204 (63%), Gaps = 10/204 (4%)
Query: 565 LLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCN 624
+L++R+ LP++K ++ +V+ + +++++V GETGSGK+TQ+ +L E S+
Sbjct: 558 ILEQRESLPIYKLKEQLVQAVHDNQILIVIGETGSGKTTQITQYLAE-----AGYTSRGK 612
Query: 625 IVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLL 684
I CTQPRR++A+S+A RV +E GC G GY IR E T + Y T G+LL
Sbjct: 613 IGCTQPRRVAAMSVAKRVSEEFGCCLGQE-----VGYTIRFEDCTSPETVIKYMTDGMLL 667
Query: 685 RKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFST 744
R+ D L+ + +++DE HER++ +D L +LK+ +QKR D+ LI+ SAT+D+ KFS
Sbjct: 668 RECLIDPDLTQYAIIMLDEAHERTIHTDVLFGLLKKTVQKRQDMKLIVTSATLDAVKFSQ 727
Query: 745 YFTHCPILRISGRSYPVEVFHLED 768
YF PI I GR+YPVE+ + ++
Sbjct: 728 YFYEAPIFTIPGRTYPVEILYTKE 751
>gi|20544129 DEAH (Asp-Glu-Ala-His) box polypeptide 35 [Homo sapiens]
Length = 703
Score = 174 bits (442), Expect = 4e-43
Identities = 123/429 (28%), Positives = 201/429 (46%), Gaps = 35/429 (8%)
Query: 867 EGAVLIFLPGLAHIQQLYDLLSNDRRFYSE-----RYKVIALHSILSTQDQAAAFTLPPP 921
+G VL FL G ++ + +L R + +V+ +++ L + +Q F
Sbjct: 274 DGDVLAFLTGQEEVETVVSMLIEQARALARTGMKRHLRVLPMYAGLPSFEQMKVFERVSR 333
Query: 922 GVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGR 981
VRK+++ATN+AET ITI +V+VID G K Y+ + + LV VS+ASA QR GR
Sbjct: 334 SVRKVIVATNVAETSITISGIVYVIDCGFVKLRAYNPRTAIECLVVVPVSQASANQRAGR 393
Query: 982 AGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPP 1041
GR R G C+R+YT E F+ +VPE+ R L + L + LG + PP
Sbjct: 394 GGRSRSGKCYRLYTEEAFDKLPQSTVPEMQRSNLAPVILQLKA--LGIDNVLRFHFMSPP 451
Query: 1042 QLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATL 1101
Q + A+ LL +G + + PLG +A P+N KML+ FGC + ++
Sbjct: 452 PAQSMVQALELLYALGGLDKDCRLTEPLGMRIAEFPLNPMFAKMLLESGNFGCSQEILSI 511
Query: 1102 AAVMTEKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYC 1161
AA+M ++ F P +K A A+ + DHLT+ N Y + K + + +C
Sbjct: 512 AAMMQIQNIFVVPPNQKSHAIRVHRKFAVEEGDHLTMLNIYEAFIK------HNKDSKWC 565
Query: 1162 RRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLV 1221
+ +FLN L+ V+++L KL+ S EG + L+ +V
Sbjct: 566 QEHFLNYKGLVRAATVREQLKKLL----VKFQVPRKSSEG----------DPDLVLRCIV 611
Query: 1222 AGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYAR 1281
+G + N + T + + +HP+SV + W++Y E I+ ++
Sbjct: 612 SGFFANAARFHSTGAYRTIRD--------DHELHIHPASVLYAEKPPRWVIYNEVIQTSK 663
Query: 1282 VYLRETTLI 1290
Y+R+ T I
Sbjct: 664 YYMRDVTAI 672
Score = 149 bits (377), Expect = 1e-35
Identities = 83/217 (38%), Positives = 135/217 (62%), Gaps = 20/217 (9%)
Query: 567 KERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIV 626
++RQ+LPVFK R+ I+ ++ ++ VV+ GETG GKSTQ+P +L E W A +
Sbjct: 49 QQRQKLPVFKLRNHILYLIENYQTVVIVGETGCGKSTQIPQYLAEA----GWTAEGRVVG 104
Query: 627 CTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACE-STRLLYCTTGVLLR 685
TQPRR++AV++A RV +E G G GY IR + + +TR+ + T G+L+R
Sbjct: 105 VTQPRRVAAVTVAGRVAEERGAVLGHE-----VGYCIRFDDCTDQLATRIKFLTDGMLVR 159
Query: 686 KLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTY 745
++ D LL+ S +++DE HER++ +D + +LK+I +KR DL LI+ SAT+D++KF +
Sbjct: 160 EMMVDPLLTKYSVIMLDEAHERTLYTDIAIGLLKKIQKKRGDLRLIVASATLDADKFRDF 219
Query: 746 FTH----------CPILRISGRSYPVEVFHLEDIIEE 772
F C IL + GR++PV++F+L+ + +
Sbjct: 220 FNQNETSDPARDTCVILTVEGRTFPVDIFYLQSPVPD 256
>gi|4503293 DEAH (Asp-Glu-Ala-His) box polypeptide 16 [Homo sapiens]
Length = 1041
Score = 167 bits (422), Expect = 8e-41
Identities = 130/424 (30%), Positives = 211/424 (49%), Gaps = 38/424 (8%)
Query: 868 GAVLIFLPGLAHIQQLYDLLSNDRRFYSERYK---VIALHSILSTQDQAAAFTLPPPGVR 924
G +L+FL G I+ ++L + R + + V+ +++ L + QA F PPG R
Sbjct: 609 GDILVFLTGQEEIEAACEMLQDPCRRLGSKIRELLVLPIYANLPSDMQARIFQPTPPGAR 668
Query: 925 KIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGR 984
K+V+ATNIAET TI +++V+D G K+ Y+ + M SL T SKASA QR GRAGR
Sbjct: 669 KVVVATNIAETSPTIEGIIYVLDPGFCKQKSYNPRTGMESLTVTPCSKASANQRAGRAGR 728
Query: 985 VRDGFCFRMYTRERFEGFM-DYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQL 1043
V G CFR+YT ++ + + +VPEI R L + L + +LG + LDPP
Sbjct: 729 VAAGKCFRLYTAWAYQHELEETTVPEIQRTSLGNVVLLLK--SLGIHDLMHFDFLDPPPY 786
Query: 1044 QVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAA 1103
+ + + L +GA + +LT G+ +A LPV+ + KM++ + C + + T+AA
Sbjct: 787 ETLLLTLEQLYALGALN-HLGELTTSGRKMAELPVDPMLSKMILASEKYSCSEEILTVAA 845
Query: 1104 VMT-EKSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCR 1162
+++ S F P + AD A+ + DHL + N Y W E GY S+ +C
Sbjct: 846 MLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQW----AESGYSSQ--WCC 899
Query: 1163 RNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVA 1222
NF+ S+ DV+++L L++ S+ + I + KA+ A
Sbjct: 900 ENFVQFRSMRRARDVREQLEGLLERVEVGLSSCQGDY-------------IRVRKAI-TA 945
Query: 1223 GLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARV 1282
G + + ++ T+S T K Q +HP+S + Q WLLY E + +
Sbjct: 946 GYFYHTARL--TRSGYRTVK-------QQQTVFIHPNSSLFEQQPR-WLLYHELVLTTKE 995
Query: 1283 YLRE 1286
++R+
Sbjct: 996 FMRQ 999
Score = 165 bits (418), Expect = 2e-40
Identities = 153/585 (26%), Positives = 265/585 (45%), Gaps = 96/585 (16%)
Query: 205 PKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERY 264
P+ E+ ++ ++ +E N +L +E+ +EE + SL+++ K +
Sbjct: 71 PRKAVVEKPARAAEREARALLEKNRSYRLLEDSEESSEETVSRAGSSLQKKRK-----KR 125
Query: 265 LHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKI-------RKFQREMETLEDHPVFNPAM 317
HL K + +E+ A+ K +K G K+ EK R + ++ LE+ F A
Sbjct: 126 KHLRKKREEEEEEEASEKGKKKTGGSKQQTEKPESEDEWERTERERLQDLEERDAF--AE 183
Query: 318 KISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKEPHDVRNFDYTARSWTGK 377
++ + +R + N+ E+S EE K+ +
Sbjct: 184 RVRQRDKDRTR-------------NVLERSDKKAYEEAQKRLK----------------- 213
Query: 378 SPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCPTILTEDGMQAQ 437
+ + K+ P K Y R R + + + L D ++
Sbjct: 214 ---------MAEEDRKAMIPELRKKSRREYLAKREREKLEDLEAELADEEFLFGDVELSR 264
Query: 438 HLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSDA--EKKREELNKMETNKPRDLFIAKL 495
H L R V RD+ E+ A ++K E N+ K A+
Sbjct: 265 HERQELKYKRRV-------------RDLAREYRAAGEQEKLEATNRYHMPKETRGQPARA 311
Query: 496 LNKLKQQQQ---QQQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNL 552
++ ++++ ++Q+ E R + + + S E L LE E +E VR
Sbjct: 312 VDLVEEESGAPGEEQRRWEEARLGAASLKFGARDAASQEPKYQLVLEEE--ETIEFVRAT 369
Query: 553 FRKLQ----------STPKYQK--LLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSG 600
+LQ ST QK + R+ LPVF R+ ++ + H+V+++ GETGSG
Sbjct: 370 --QLQGDEEPSAPPTSTQAQQKESIQAVRRSLPVFPFREELLAAIANHQVLIIEGETGSG 427
Query: 601 KSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCG 660
K+TQ+P +L E+ N+ I CTQPRR++A+S+A RV E+G + G + G
Sbjct: 428 KTTQIPQYLFEEGYTNKG----MKIACTQPRRVAAMSVAARVAREMGVKLG-----NEVG 478
Query: 661 YQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKE 720
Y IR E E T L Y T G+LLR+ + L++ S V+VDE HER++ +D L ++K+
Sbjct: 479 YSIRFEDCTSERTVLRYMTDGMLLREFLSEPDLASYSVVMVDEAHERTLHTDILFGLIKD 538
Query: 721 ILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFH 765
+ + R +L +++ SAT+D+ +FST+F P+ RI GR +PV++F+
Sbjct: 539 VARFRPELKVLVASATMDTARFSTFFDDAPVFRIPGRRFPVDIFY 583
>gi|169211440 PREDICTED: similar to DEAH (Asp-Glu-Ala-His) box
polypeptide 40 [Homo sapiens]
Length = 452
Score = 152 bits (383), Expect = 3e-36
Identities = 131/461 (28%), Positives = 217/461 (47%), Gaps = 82/461 (17%)
Query: 573 PVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRR 632
P+ K R I++ ++ + ++V G TGSGK+TQ+P +L E + I TQPR+
Sbjct: 54 PIQKQRKKIIQAVRDNSFLIVTGNTGSGKTTQLPKYLYEAGF-----SQHGMIGVTQPRK 108
Query: 633 ISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDGL 692
++A+S+A RV +E+ C G S GYQ+R + + + T + Y T G LL+ + D
Sbjct: 109 VAAISVAQRVAEEMKCTLG-----SKVGYQVRFDDCSSKETAIKYMTDGCLLKHILGDPN 163
Query: 693 LSNVSHVIVDEVHERSVQSDFLLIILKEILQKRS-----DLHLILMSATVDSEKFSTYFT 747
L+ S +I+DE HER++ +D L +LK++ Q++S L +++MSAT++ K S +F
Sbjct: 164 LTKFSVIILDEAHERTLTTDILFGLLKKLFQEKSPNRKEHLKVVVMSATMELAKLSAFFG 223
Query: 748 HCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGIKK 807
+CPI I GR YPV E G +++ Y Q ++ ++ +N AG I
Sbjct: 224 NCPIFDIPGRLYPVR----EKFCNLIGPRDRENTAYIQAIVKVTMDIHLN--EMAGDI-- 275
Query: 808 YQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIE 867
+ TG ++ +L+ ++ D Q ++
Sbjct: 276 ----LVFLTG----------QFEIEKSCELLFQMAESVDYDY----------DVQDTILD 311
Query: 868 GAVLIFLPGLAHIQQLYDLLSND--RRFYSERYKVIALHSILSTQDQAAAFTLPPPGVRK 925
G L+ LP Y ++ D RR + I ++ST A + T+ G+R
Sbjct: 312 G--LLILP-------CYGSMTTDQQRRIFLPPPPGIR-KCVISTNISATSLTI--DGIRY 359
Query: 926 IVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRV 985
+V D G K+ ++ + L +SK+ ALQR GRAGR
Sbjct: 360 VV-------------------DGGFVKQLNHNPRLGLDILEVVPISKSEALQRSGRAGRT 400
Query: 986 RDGFCFRMYTRERFEGFM-DYSVPEILRVPLEELCLHIMKC 1025
G CFR+Y+++ + M D+ +PEI R L + L +KC
Sbjct: 401 SSGKCFRIYSKDFWNQCMPDHVIPEIKRTSLTSVVL-TLKC 440
>gi|29029601 DEAH (Asp-Glu-Ala-His) box polypeptide 37 [Homo sapiens]
Length = 1157
Score = 139 bits (350), Expect = 2e-32
Identities = 117/416 (28%), Positives = 192/416 (46%), Gaps = 41/416 (9%)
Query: 900 VIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHES 959
V+ L+S+L+ + QA F PP G R V+ATN+AET +TIP + +V+D G+ K+ Y
Sbjct: 590 VLPLYSLLAPEKQAQVFKPPPEGTRLCVVATNVAETSLTIPGIKYVVDCGKVKKRYYDRV 649
Query: 960 SQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEGFMDYSVPEILRVPLEELC 1019
+ +SS T+VS+ASA QR GRAGR G C+R+Y+ F F + PEI R P+E+L
Sbjct: 650 TGVSSFRVTWVSQASADQRAGRAGRTEPGHCYRLYSSAVFGDFEQFPPPEITRRPVEDLI 709
Query: 1020 LHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGAC----------ELNEPKL--- 1066
L + N+ +F PP ++ + A LL +GA +L E +L
Sbjct: 710 LQMKALNVEKVINFPFPT--PPSVEALLAAEELLIALGALQPPQKAERVKQLQENRLSCP 767
Query: 1067 -TPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVATLAAVMTEKSPF---TTPIGRKDEAD 1122
T LG+ +A PV + KML GCL T+ A MT + F P +E
Sbjct: 768 ITALGRTMATFPVAPRYAKMLALSRQHGCLPYAITIVASMTVRELFEELDRPAASDEELT 827
Query: 1123 LAKSALA-----------MADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSL 1171
KS A S L LG A + + +C N L ++
Sbjct: 828 RLKSKRARVAQMKRTWAGQGASLKLGDLMVLLGAVGACEYASCTPQ--FCEANGLRYKAM 885
Query: 1172 LTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKI 1231
+ + ++ +L V A + Q + ++ L+ ++ AGL D++ +
Sbjct: 886 MEIRRLRGQLTTAVNAV-----CPEAELFVDPKMQPPTESQVTYLRQIVTAGLGDHLARR 940
Query: 1232 IYTKSVDVTEKLACIVET--AQGKAQVHPSSVNRDLQTHGWLLYQEKIRYARVYLR 1285
+ ++ + + +K +T +HPSSV + +++YQE + ++Y++
Sbjct: 941 VQSEEM-LEDKWRNAYKTPLLDDPVFIHPSSV-LFKELPEFVVYQEIVETTKMYMK 994
Score = 131 bits (330), Expect = 4e-30
Identities = 90/291 (30%), Positives = 148/291 (50%), Gaps = 37/291 (12%)
Query: 500 KQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPV---------- 549
++++++++ SE + E+ D + + E + + L A +PV
Sbjct: 161 EEEEEEEESESELEEESELDEDPAAEPAEAGVGTTVAPLPPAPAPSSQPVPAGMTVPPPP 220
Query: 550 -------RNLFRKLQSTP--KYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSG 600
R L + P + ++ +ER +LP+ I+E + H +V+V GETGSG
Sbjct: 221 AAAPPLPRALAKPAVFIPVNRSPEMQEERLKLPILSEEQVIMEAVAEHPIVIVCGETGSG 280
Query: 601 KSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCG 660
K+TQVP FL E +E I T+PRR++AV+++ RV E+ +
Sbjct: 281 KTTQVPQFLYEAGFSSEDSI----IGVTEPRRVAAVAMSQRVAKEMNLSQ------RVVS 330
Query: 661 YQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKE 720
YQIR E E TR+ + T GVLL+++Q+D LL VI+DE HERSV +D L+ +L
Sbjct: 331 YQIRYEGNVTEETRIKFMTDGVLLKEIQKDFLLLRYKVVIIDEAHERSVYTDILIGLLSR 390
Query: 721 ILQKRS----DLHLILMSATVDSEKFS----TYFTHCPILRISGRSYPVEV 763
I+ R+ L L++MSAT+ E F+ + P++++ R +PV V
Sbjct: 391 IVTLRAKRNLPLKLLIMSATLRVEDFTQNPRLFAKPPPVIKVESRQFPVTV 441
>gi|20336300 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 32 [Homo
sapiens]
Length = 743
Score = 135 bits (340), Expect = 3e-31
Identities = 86/259 (33%), Positives = 140/259 (54%), Gaps = 13/259 (5%)
Query: 513 KRENSEDPEESWENLVSDEDFSALSLESANV---EDLEPVRNLFRKLQSTPKYQKLLKER 569
+ E E P S E E + + V EDLE N F L + +Y KLLKER
Sbjct: 2 EEEGLECPNSSSEKRYFPESLDSSDGDEEEVLACEDLE--LNPFDGLPYSSRYYKLLKER 59
Query: 570 QQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQ 629
+ LP++K + S +E L ++++V+V+G+ GKS QVP + E L ++ ++CTQ
Sbjct: 60 EDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHG--GVICTQ 117
Query: 630 PRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQE 689
+ + V LA RV DE+ G GY I E+ T L YCT +L R++
Sbjct: 118 VHKQTVVQLALRVADEMDVNIGHE-----VGYVIPFENCCTNETILRYCTDDMLQREMMS 172
Query: 690 DGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHC 749
+ L + +I+D++HERS+ +D LL +LK++L R +L LI+ S+ K ++Y+ +
Sbjct: 173 NPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNV 232
Query: 750 PILRISGRSYPVEVFHLED 768
P++ + + +PVEV +L +
Sbjct: 233 PVIEVKNK-HPVEVVYLSE 250
Score = 84.0 bits (206), Expect = 9e-16
Identities = 90/379 (23%), Positives = 169/379 (44%), Gaps = 36/379 (9%)
Query: 924 RKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAG 983
R++VL T+ E I V FVID G + Y+ + +SLV +S++ A R+ G
Sbjct: 334 RRVVLTTSSGEFLIWSNSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILG 393
Query: 984 RVRDGFCFRMYTRERFEGFMDYSVP-EILRVPLEELCLHIMKCNLGSPE--DFLSKALDP 1040
G F +YT E M P E+ L + L + + ++ DF+++
Sbjct: 394 SSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNR---- 449
Query: 1041 PQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVAT 1100
P + + A+ L + A + N+ L+ G ++ P++ ++ K ++ F C+D V T
Sbjct: 450 PAPESLMQALEDLDYLAALD-NDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLT 508
Query: 1101 LAAVMTEKSPFT-TPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEIT 1159
+AA++T + F+ P G ++ A + DH T+ + Y KA Q+ S
Sbjct: 509 IAAMVTAPNCFSHVPHGAEEAALTCWKTFLHPEGDHFTLISIY----KAYQDTTLNSSSE 564
Query: 1160 Y-----CRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIA 1214
Y CR FLN ++L + ++ EL++++K + + + N +
Sbjct: 565 YCVEKWCRDYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLN--------- 615
Query: 1215 LLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQGKAQVHP-SSVNRDLQTHGWLLY 1273
+K L++G + + + DV ++ T + AQ+HP S + + W+L+
Sbjct: 616 -IKKALLSGYFMQIAR-------DVDGSGNYLMLTHKQVAQLHPLSGYSITKKMPEWVLF 667
Query: 1274 QEKIRYARVYLRETTLITP 1292
+ Y+R T+ I+P
Sbjct: 668 HKFSISENNYIRITSEISP 686
>gi|163914394 DEAQ box polypeptide 1 (RNA-dependent ATPase) [Homo
sapiens]
Length = 717
Score = 90.5 bits (223), Expect = 1e-17
Identities = 67/208 (32%), Positives = 110/208 (52%), Gaps = 11/208 (5%)
Query: 551 NLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHR--VVVVAGETGSGKSTQVPHF 608
N F L + +Y +LLK+RQ LP++ R + +E L+ + VV+V+GE GSGKSTQ+P +
Sbjct: 24 NPFDGLPFSSRYYELLKQRQALPIWAARFTFLEQLESNPTGVVLVSGEPGSGKSTQIPQW 83
Query: 609 LLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESR 668
E L ++ K + TQP ++A SLA RV DE+ G GY I E
Sbjct: 84 CAEFALARGFQ--KGQVTVTQPYPLAARSLALRVADEMDLTLG-----HEVGYSIPQEDC 136
Query: 669 ACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKR--S 726
+T L +C +LL+++ +++DE ERSV SD L +L++ ++
Sbjct: 137 TGPNTLLRFCWDRLLLQEVASTRGTGAWGVLVLDEAQERSVASDSLQGLLQDARLEKLPG 196
Query: 727 DLHLILMSATVDSEKFSTYFTHCPILRI 754
DL +++++ K ++ + PI+ I
Sbjct: 197 DLRVVVVTDPALEPKLRAFWGNPPIVHI 224
Score = 85.5 bits (210), Expect = 3e-16
Identities = 92/374 (24%), Positives = 159/374 (42%), Gaps = 33/374 (8%)
Query: 864 RNIEGAVLIFLPGLAHIQQLYDLLSNDRR---FYSERYKVIALHSILSTQDQAAAFTLPP 920
+ + G VL+FLP I + LS + +V+ LH QA +
Sbjct: 258 KELPGDVLVFLPSEEEISLCCESLSREVESLLLQGLPPRVLPLHPDCGRAVQAVYEDMD- 316
Query: 921 PGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQG 980
RK+V+ +A+ ++P + VID+G + Y+ + V +SK A R+
Sbjct: 317 --ARKVVVTHWLADFSFSLPSIQHVIDSGLELRSVYNPRIRAEFQVLRPISKCQAEARRL 374
Query: 981 RAGRVRDGFCFRMYTRERFE-GFMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALD 1039
RA G C +Y + E P + L L L + + + P + LD
Sbjct: 375 RARGFPPGSCLCLYPKSFLELEAPPLPQPRVCEENLSSLVLLLKRRQIAEPGE--CHFLD 432
Query: 1040 PPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVNVKIGKMLIFGAIFGCLDPVA 1099
P + + A+ L + A + ++ L+ LG L+ P+ ++ K L+ F C+D +
Sbjct: 433 QPAPEALMQALEDLDYLAALD-DDGDLSDLGVILSEFPLAPELAKALLASCEFDCVDEML 491
Query: 1100 TLAAVMTEKSPFTTPIGRKDEADLAKSALAMADSDH---LTIYNAYLGWKKARQEGGYRS 1156
TLAA++T FT P +EA L + AL D DH + +Y A++ Q G +
Sbjct: 492 TLAAMLTAAPGFTRPPLSAEEAAL-RRALEHTDGDHSSLIQVYEAFI------QSG---A 541
Query: 1157 EITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTTSTSWEGNRASQTLSFQEIALL 1216
+ +C+ LN +L ++ EL++L++ S + E NR L
Sbjct: 542 DEAWCQARGLNWAALCQAHKLRGELLELMQRIELPLSLPAFGSEQNRRD----------L 591
Query: 1217 KAVLVAGLYDNVGK 1230
+ LV+G + V +
Sbjct: 592 QKALVSGYFLKVAR 605
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 50.8 bits (120), Expect = 9e-06
Identities = 57/202 (28%), Positives = 90/202 (44%), Gaps = 22/202 (10%)
Query: 166 LSDDALPEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKP--KKEEK 223
+ + P +E ++ S K + + QAT P K KT +++ K KP KKEEK
Sbjct: 594 IKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEK 653
Query: 224 ---NMEVNMKE---WILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQ 277
EV KE I + + + EE K E K +++EEK +P + K KE
Sbjct: 654 EKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKE----VKKETPPKEV 709
Query: 278 AATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGES 337
K E+ K+ +KE +E ++E++ L A K S +E KK P A + +
Sbjct: 710 KKEVKKEEKKEVKKEEKEP----KKEIKKLP-----KDAKKSSTPLSEAKK-PAALKPKV 759
Query: 338 ALNFNLFEKSAAATEEEKDKKK 359
+K + A + K+K K
Sbjct: 760 PKKEESVKKDSVAAGKPKEKGK 781
Score = 30.8 bits (68), Expect = 9.3
Identities = 42/209 (20%), Positives = 84/209 (40%), Gaps = 18/209 (8%)
Query: 172 PEGFSQEFEEQQPKSRP--KFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNM 229
PE +++FEE + + K PQ++ +T+ E K ++ K +
Sbjct: 833 PEDLTKDFEELKAEEVDVTKDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESP 892
Query: 230 KEWILRY-----AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLE 284
E I EQ EE + + +++ EKF+ +++ D +E+A T E
Sbjct: 893 DEGITTTEGEGECEQTPEELEPVEKQGVDDIEKFEDEGAGFEESSETGDYEEKAET---E 949
Query: 285 KNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLF 344
+ ++ +++ +E + + ED + K R+K G+ ++
Sbjct: 950 EAEEPEEDGEEHVCVSASKHSPTEDEE----SAKAEADAYIREKRESVASGDDRAEEDMD 1005
Query: 345 EK----SAAATEEEKDKKKEPHDVRNFDY 369
E A +EEE D++ + D R +Y
Sbjct: 1006 EAIEKGEAEQSEEEADEEDKAEDAREEEY 1034
>gi|221219020 NYD-SP11 protein [Homo sapiens]
Length = 2873
Score = 49.3 bits (116), Expect = 3e-05
Identities = 37/152 (24%), Positives = 70/152 (46%), Gaps = 6/152 (3%)
Query: 151 YGGDLHSALDWLCLNLSDDALPEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTY 210
+ ++ S LD L ++L +E EE++ + + + + + + K
Sbjct: 2226 FSEEMESLLDEL---EKQESLSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEK 2282
Query: 211 EEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAK 270
EE+ K K KKE+K EV KE + E+ EE+ E+ EEEE+ E + +
Sbjct: 2283 EEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Query: 271 LLDAKEQAATFKLEKNKQGQKEAQEKIRKFQR 302
+L ++Q FKL++ ++ +E++ R
Sbjct: 2343 ILKKEKQ---FKLQEQRRKSLRGRERVLSILR 2371
Score = 36.2 bits (82), Expect = 0.22
Identities = 35/151 (23%), Positives = 66/151 (43%), Gaps = 34/151 (22%)
Query: 210 YEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAA 269
+ E+ +S + EK ++ +E E++ EEE+ E EEEE+ + E
Sbjct: 2226 FSEEMESLLDELEKQESLSSEE----EEEREEEEEREEEEVREEEEERKEEEEGE----- 2276
Query: 270 KLLDAKEQAATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKP 329
EK + ++E ++K +K +++ E E VF E K+
Sbjct: 2277 --------------EKQVEKEEEEKKKKKKEKKKEEVQEKEEVF-----------EEKEE 2311
Query: 330 PVATEGESALNFNLFEKSAAATEEEKDKKKE 360
++ E +L+ E+ + + EEE D++KE
Sbjct: 2312 IMSEEETESLSDEEEEEESCSLEEEVDREKE 2342
Score = 32.7 bits (73), Expect = 2.4
Identities = 34/149 (22%), Positives = 66/149 (44%), Gaps = 20/149 (13%)
Query: 169 DALPEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVN 228
D E FS + +E + + S ++++ + L+ + E+ + + ++EE+ E
Sbjct: 2207 DKPKEKFSSQVDEVESEEH---FSEEMESLLDE-LEKQESLSSEEEEEREEEEEREEEEV 2262
Query: 229 MKEWILRYAEQQNEE---EKNENSKS-----------LEEEEKFDPNERYL--HLAAKLL 272
+E R E++ EE EK E K E+EE F+ E + L
Sbjct: 2263 REEEEERKEEEEGEEKQVEKEEEEKKKKKKEKKKEEVQEKEEVFEEKEEIMSEEETESLS 2322
Query: 273 DAKEQAATFKLEKNKQGQKEAQEKIRKFQ 301
D +E+ + LE+ +KE +K ++F+
Sbjct: 2323 DEEEEEESCSLEEEVDREKEILKKEKQFK 2351
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 48.1 bits (113), Expect = 6e-05
Identities = 72/369 (19%), Positives = 155/369 (42%), Gaps = 52/369 (14%)
Query: 180 EEQQPKSRPKFQSPQIQA-TISPPLQPKTKTYEEDPKSKPKKEEK--NMEVNMKEWILRY 236
E ++ R KF PQ+Q T+ + + + E K K+EEK E ++E +
Sbjct: 212 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 271
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKE--QAATFKLEKNKQGQKEAQ 294
EQ+ E+ + + + E+E++ E+ L KL + +E Q K+ + ++ +E +
Sbjct: 272 REQE-EKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQE 330
Query: 295 EKI-----RKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAA 349
EK+ R +++E + E + +Q+ER + E ++E+
Sbjct: 331 EKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE---KMWEQEEK 387
Query: 350 ATEEEKDKKKEPHDVRNFDYTARSWTGKSPK-------QFLIDWVRKNLPKSPNPSFEKV 402
EEE+ +++E +R + T R K K Q +W ++ LP+ +E
Sbjct: 388 MQEEERIRERE-KKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWE-- 444
Query: 403 PVGRYWKCRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTY 462
+ ++ + E+ + I ++ M Q ++R K + +
Sbjct: 445 --------QEKMQEQEEKIWEQEEKIRDQEEMWGQE----KKMWRQEKMREQEDQM---- 488
Query: 463 RDVWLEWSDAEKKREELNKMETNKPR----DLFIAKLLNKLKQQQQ--QQQQHSENKREN 516
W EK R++ KM + R D + + ++++Q++ QQ++ +++
Sbjct: 489 ------WEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKT 542
Query: 517 SEDPEESWE 525
E +++W+
Sbjct: 543 QEQEKKTWD 551
Score = 43.5 bits (101), Expect = 0.001
Identities = 32/200 (16%), Positives = 88/200 (44%), Gaps = 6/200 (3%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRY 236
+E EE+ + + +Q + + + KT++++ K + ++ + E M+E
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEK 296
EQ+ + ++ E +EE+ ++ E+ K+ + +E+ E+ ++ + + QE+
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEK----MWEQEEEDKMQEQEE 632
Query: 297 IRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEE--E 354
+ Q E ++ ++ K+ Q+ + ++ +G+ EK E+ E
Sbjct: 633 MMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMRE 692
Query: 355 KDKKKEPHDVRNFDYTARSW 374
+++K + + + + W
Sbjct: 693 QEEKMRGQEEKMWGQEEKMW 712
Score = 40.8 bits (94), Expect = 0.009
Identities = 66/374 (17%), Positives = 139/374 (37%), Gaps = 56/374 (14%)
Query: 180 EEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQ 239
+E++ + + K + + ++ + K E+ ++ ++EEK + W E
Sbjct: 371 KEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEW 430
Query: 240 QNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKE----QAATFKLEKNKQGQK---E 292
Q + + K E+E+ + E+ K+ D +E + ++ EK ++ + E
Sbjct: 431 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWE 490
Query: 293 AQEKIRKFQREM-----------ETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNF 341
+EK+R +++M E L + K QQ E+ + T+ + +
Sbjct: 491 QEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTW 550
Query: 342 NLFEK---SAAATEEEKDKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPS 398
+ EK E EK ++E +R + + K +Q W ++ +
Sbjct: 551 DQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE- 609
Query: 399 FEKVPVGRYWKCRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLL 458
+ W+ ++ + E+ ED MQ Q + + K Q + +
Sbjct: 610 -------KMWEQEEKMWEQEE-----------EDKMQEQE---EMMWEQEEKMQEQEEKM 648
Query: 459 PPTYRDVWLEWSDAEKKREELNKMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSE 518
W EK RE+ KM + + + K+++Q+++ Q E RE E
Sbjct: 649 ----------WEQEEKMREQEEKMREQEEK---MQGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 519 DPEESWENLVSDED 532
E + E+
Sbjct: 696 KMRGQEEKMWGQEE 709
Score = 39.3 bits (90), Expect = 0.026
Identities = 29/137 (21%), Positives = 61/137 (44%), Gaps = 7/137 (5%)
Query: 176 SQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILR 235
+QE E++ K + + ++ + + E + ++EEK E K W
Sbjct: 542 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQE 601
Query: 236 YAEQQNEE---EKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKE 292
Q+ EE E+ E EEE+K E + + + +E+ K+ + ++ +E
Sbjct: 602 EKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE----KMWEQEEKMRE 657
Query: 293 AQEKIRKFQREMETLED 309
+EK+R+ + +M+ E+
Sbjct: 658 QEEKMREQEEKMQGQEE 674
Score = 37.7 bits (86), Expect = 0.076
Identities = 32/136 (23%), Positives = 61/136 (44%), Gaps = 5/136 (3%)
Query: 177 QEFEEQQPKSRPKF--QSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWIL 234
+E EEQ + K Q +++ + + + +E++ K ++E+K + + W
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE-KQMREQEQKMRDQEERMWEQ 364
Query: 235 RYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKE--QAATFKLEKNKQGQKE 292
++ EE E K E+EEK ER K+ + +E + K++K ++ E
Sbjct: 365 DERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 424
Query: 293 AQEKIRKFQREMETLE 308
+EK + QR E E
Sbjct: 425 QEEKEWQQQRLPEQKE 440
Score = 35.0 bits (79), Expect = 0.49
Identities = 72/375 (19%), Positives = 145/375 (38%), Gaps = 39/375 (10%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKK---EEKNMEVNMKEWI 233
+E EQ+ K R + + Q + K + EE + + K+ +EK + KE
Sbjct: 241 EELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELR 300
Query: 234 ----LRYAEQQNEEEKN----ENSKSLEEEEK-FDPNERYLHLAAKLLDAKEQAATFKLE 284
LR E+Q +E++ + K E+EEK + ER L K + +EQ K+
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEER-LWEQEKQMREQEQ----KMR 355
Query: 285 KNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLF 344
++ E E++R+ + M E ++ K+ ++ R++ E E
Sbjct: 356 DQEERMWEQDERLREKEERMR--EQEKMWEQEEKMQEEERIREREKKMREEEE------- 406
Query: 345 EKSAAATEEEKDKKKEPHDVRNFDYTARSW-TGKSPKQFLIDWVRKNLPKSPNPSFEKVP 403
T E+++K + + ++ + W + P+Q W ++ + + +E+
Sbjct: 407 ------TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEE 460
Query: 404 VGR----YWKCRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLP 459
R W ++ + E E+ M+ Q R+ + +
Sbjct: 461 KIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKE 520
Query: 460 PTYRDVWLEWSDAEKKREELNKMETNKPRDLFIAKLL--NKLKQQQQQQQQHSENKRENS 517
R+ W EK REE E K K+ ++++++++ ++ E RE
Sbjct: 521 ERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 580
Query: 518 EDPEESWENLVSDED 532
E +E E + E+
Sbjct: 581 EKMQEQEEKMREQEE 595
Score = 35.0 bits (79), Expect = 0.49
Identities = 69/384 (17%), Positives = 147/384 (38%), Gaps = 66/384 (17%)
Query: 173 EGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEW 232
EG +E EE+ + + + + + L+ + K E K + ++EE+ E K W
Sbjct: 268 EGKMREQEEKMRRQEKRLREQEKE------LREQEKELREQKKLR-EQEEQMQEQEEKMW 320
Query: 233 ILRYAEQQNEEEKNENSKSLEEEEKFDPNERYL-------------------HLAAKLLD 273
+Q E+ + + K +EE+ E+ + L K
Sbjct: 321 ------EQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEER 374
Query: 274 AKEQAATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVAT 333
+EQ ++ E+ Q ++ +E+ +K + E ET+ + K E+++
Sbjct: 375 MREQEKMWEQEEKMQEEERIREREKKMREEEETMREQE--EKMQKQEENMWEQEEKEWQQ 432
Query: 334 EGESALNFNLFEKSAAATEEEKDKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPK 393
+ L+E+ +EEK ++E +R+ + W G+ K W ++ + +
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQE-EKIRDQE---EMW-GQEKKM----WRQEKMRE 483
Query: 394 SPNPSFEKVPVGR-----YWKCRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRL 448
+ +E+ R W R+ + ++ + E+ M+ Q ++
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLRE------KEERMREQK--------KM 529
Query: 449 VKGQSVHQLLPPTYRDVWLEWSDAEKKREELNKMETNKPRDLFIAKLLNKLKQQQQQQQQ 508
+ + + T W EK REE E + R+ + + +++Q+++ Q+
Sbjct: 530 WQQEEKMREEKKTQEQEKKTWDQEEKMREE----ERMREREKKMREEEEMMREQEEKMQE 585
Query: 509 HSENKRENSEDPEESWENLVSDED 532
E RE E E E + E+
Sbjct: 586 QEEKMREQEEKMWEQEEKMQEQEE 609
Score = 30.8 bits (68), Expect = 9.3
Identities = 30/128 (23%), Positives = 56/128 (43%), Gaps = 10/128 (7%)
Query: 469 WSDAEKKREELNKMETNKPR----DLFIAKLLNKLKQQQQQQQQHSENKRENSE---DPE 521
W EK RE+ KM + R + + + K++ Q+++ + E RE E + E
Sbjct: 320 WEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379
Query: 522 ESWENLVS-DEDFSALSLESANVEDLEPVRNLFRKLQSTPK--YQKLLKERQQLPVFKHR 578
+ WE E+ E E+ E +R K+Q + +++ KE QQ + + +
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 439
Query: 579 DSIVETLK 586
+ + E K
Sbjct: 440 EKLWEQEK 447
>gi|120587019 zinc finger protein 318 [Homo sapiens]
Length = 2279
Score = 47.4 bits (111), Expect = 1e-04
Identities = 89/449 (19%), Positives = 162/449 (36%), Gaps = 83/449 (18%)
Query: 181 EQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQ 240
+Q +SRP + + P + P +E + + ++V++ ++RY ++
Sbjct: 826 KQATRSRPNLR-------VIPTVTPDKPKQKESLRGSIPAAQVPVQVSIPS-LIRYNPEK 877
Query: 241 NEEEKNENS---KSLEEEEKFDPNER--------YLHLAAKLLDAKEQAATFKLEKNKQG 289
+EKN S K +EE EK N+R YL + L ++ K + K G
Sbjct: 878 ISDEKNRASQKQKVIEEREKLK-NDREARQKKMYYLRTELERLHKQQGEMLRKKRREKDG 936
Query: 290 QKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAA 349
K+ E+ L+D+ + + A + KK + L N+F+KS
Sbjct: 937 HKDP------LLVEVSRLQDNIMKDIAELRQEAEEAEKKQSELDKVAQILGINIFDKSQK 990
Query: 350 ATEEEK---------DKKKEPHDVRNFDYTA---------RSWTGKSPKQFLIDWVRKNL 391
+ + + +K K P V +F ++ + KSPK
Sbjct: 991 SLSDSREPTEKPGKAEKSKSPEKVSSFSNSSSNKESKVNNEKFRTKSPKPAESPQSATKQ 1050
Query: 392 PKSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKG 451
P ++E G +W C+ D +C G + +
Sbjct: 1051 LDQPTAAYEYYDAGNHW-CK--------DCNTIC--------------GTMFDFFTHMHN 1087
Query: 452 QSVHQLLPPTYRDVWLEWSDAEKKREELNK----------METNKPRDLFIAKLLNKLKQ 501
+ Q L P Y W + +E K++ + + E P F +L +
Sbjct: 1088 KKHTQTLDP-YNRPWASKTQSEAKQDAIKRTDKITVPAKGSEFLVPISGFYCQLCEEFLG 1146
Query: 502 QQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLESANVEDLEPVR----NLFRKLQ 557
+QH + + N + + EN + +E + L ++ LE R L RKL
Sbjct: 1147 DPISGEQHVKGHQHNEKYKKYVDENPLYEERRN-LDRQAGLAVVLETERRRQSELKRKLS 1205
Query: 558 STPKYQKLLKERQQLPVFKHRDSIVETLK 586
PK +K K+ + + K D + E L+
Sbjct: 1206 EKPKEEKKEKKAKAVKEVKEDDKVSEKLE 1234
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 46.2 bits (108), Expect = 2e-04
Identities = 39/186 (20%), Positives = 82/186 (44%), Gaps = 16/186 (8%)
Query: 177 QEFEEQQPKSRPKF--QSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWIL 234
Q+ EEQ K + Q Q++ L+ K +T +E+ + +++ + E M+E
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310
Query: 235 RYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQ 294
+ EQ+ + + E +EE+ ++ E+ ++ +EQ E+ +Q QK+ +
Sbjct: 311 QMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG----EQEEQMQKQ-E 365
Query: 295 EKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEE 354
E++RK + +M E+ +Q E+ + GE ++ EE+
Sbjct: 366 EQVRKQEEQMRKQEEQ---------MRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQ 416
Query: 355 KDKKKE 360
++KE
Sbjct: 417 MGEQKE 422
Score = 35.4 bits (80), Expect = 0.38
Identities = 58/357 (16%), Positives = 136/357 (38%), Gaps = 69/357 (19%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEE-KNMEVNMKEWILR 235
QE + ++ + + + Q Q++ + + + E++ + + ++ + + E M E +
Sbjct: 141 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQ 200
Query: 236 YAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQE 295
EQ+ + + E +EE+ + E+ ++ + +EQ ++K ++ ++ +E
Sbjct: 201 MGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQ-----VQKQEEQVQKQEE 255
Query: 296 KIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEK 355
++RK + +M E+ ++ Q+ + K TE E E+ E+E+
Sbjct: 256 QMRKQEEQMREQEE--------QMREQEEQMLKQKEQTEQEEQTG----EQEEQMREQEE 303
Query: 356 DKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVI 415
+++ +R + R + KQ W +K + W+ + ++
Sbjct: 304 QMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKE---------------QMWEQKEQMW 348
Query: 416 KSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSDAEKK 475
K E+ + E+ MQ Q V + K+
Sbjct: 349 KQEEQMGE------QEEQMQKQE------------------------EQVRKQEEQMRKQ 378
Query: 476 REELNKMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSDED 532
E++ K E + K ++ +Q++Q + E RE E E E + E+
Sbjct: 379 EEQMRKQEEQ------MRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429
Score = 30.8 bits (68), Expect = 9.3
Identities = 25/135 (18%), Positives = 62/135 (45%), Gaps = 6/135 (4%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEK-NMEVNMKEWILR 235
QE + ++ + + + Q Q++ + + + +E+ + +KE+ E M E +
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360
Query: 236 YAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQE 295
+Q+ + K E +EE+ E+ ++ + KEQ + + K+ +E +E
Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQ-----MGEQKEQMREQEE 415
Query: 296 KIRKFQREMETLEDH 310
++ + + +M E+H
Sbjct: 416 QMGEQKEQMRKQEEH 430
>gi|63054848 coiled-coil domain containing 34 isoform 1 [Homo
sapiens]
Length = 373
Score = 45.1 bits (105), Expect = 5e-04
Identities = 41/126 (32%), Positives = 60/126 (47%), Gaps = 20/126 (15%)
Query: 206 KTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYL 265
K K EE K K EEK+ KEW+ + EQ+ +E + + +K +EE+ + + YL
Sbjct: 174 KRKEMEEREKRKIIAEEKH-----KEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYL 228
Query: 266 HLAA--------KLLDAKE-QAATFKLEKNKQGQKEAQEK----IRKFQREMETLEDHPV 312
A K +A+E + + EK KQ Q E QEK +KFQ +E + P
Sbjct: 229 QEKAKEKYQEWLKKKNAEECERKKKEKEKEKQQQAEIQEKKEIAEKKFQEWLENAKHKP- 287
Query: 313 FNPAMK 318
PA K
Sbjct: 288 -RPAAK 292
Score = 36.2 bits (82), Expect = 0.22
Identities = 32/152 (21%), Positives = 66/152 (43%), Gaps = 15/152 (9%)
Query: 211 EEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEE-EEKFDPNERYLHLAA 269
E + + +K+ + E + W + + ++ EE K+LEE ++ + +
Sbjct: 124 ESENNQEEQKQVRLPESRLTPWEVWFIGKEKEERDRLQLKALEELNQQLEKRKEMEEREK 183
Query: 270 KLLDAKEQAATFKLEKNKQGQKEAQEKIRKFQREMETLE-DHPVFNPAMKISHQQNERKK 328
+ + A+E+ + +KN+Q +KE ++KI K E E + K +Q+ +KK
Sbjct: 184 RKIIAEEKHKEWVQKKNEQKRKEREQKINKEMEEKAAKELEKEYLQEKAKEKYQEWLKKK 243
Query: 329 PPVATEGESALNFNLFEKSAAATEEEKDKKKE 360
N E E+EK+K+++
Sbjct: 244 -------------NAEECERKKKEKEKEKQQQ 262
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 44.7 bits (104), Expect = 6e-04
Identities = 63/362 (17%), Positives = 138/362 (38%), Gaps = 48/362 (13%)
Query: 176 SQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILR 235
+QE E++ K + + ++ + + E + ++EEK E K W
Sbjct: 571 TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMW--- 627
Query: 236 YAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQE 295
+Q E+ + + K E+EEK E + +L + KE+ + + ++ +E +E
Sbjct: 628 ---EQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEE 684
Query: 296 KIRKFQR-EMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEE 354
KI + ++ E +T E K+ +++ R++ E E + + +E
Sbjct: 685 KIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMM------REQEEKMQE 738
Query: 355 KDKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRV 414
+++K + + ++ + W + W ++ LP+ +E + K +
Sbjct: 739 QEEKMQEQEEEMWEQEEKMWEQEEKM-----WEQQRLPEQKEKLWEHEKMQEQEKIWEQE 793
Query: 415 IKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLE----WS 470
K D E+ M+ Q ++GQ + + +W + W
Sbjct: 794 EKMRDQ----------EEKMRGQE--------EKMRGQ--EEKMRGQEEKMWGQEEKMWG 833
Query: 471 DAEKKREELNKMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSD 530
EK + KM + K+ K++ Q+++ ++ E R E E E +
Sbjct: 834 QEEKMWGQEEKMWGQE------EKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQ 887
Query: 531 ED 532
E+
Sbjct: 888 EE 889
Score = 43.9 bits (102), Expect = 0.001
Identities = 56/354 (15%), Positives = 145/354 (40%), Gaps = 36/354 (10%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRY 236
++ +EQ+ K+R + + Q + I + + K E+ ++ ++EEK + W
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERI----REREKKMREEEETMREQEEKMQKQEENMWEQEE 485
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEK 296
E Q + + K E+E+ + E+ K+ D +E K ++ +E +++
Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQ 545
Query: 297 IRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKD 356
+ + + +M ++ +++ ++ + E++K E + + E+ EEE+
Sbjct: 546 MWEQEEKMRD-QEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604
Query: 357 KKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRV-- 414
+++ ++ + + K +Q + + + +E+ + W+ ++
Sbjct: 605 MREQEEKMQEQEEKMQEQEEKMWEQ------EEKMQEQEEKMWEQEE--KMWEQEEKMWE 656
Query: 415 ---IKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSD 471
+ + + L + ++ MQ Q ++ + + + + + W D
Sbjct: 657 QQRLPEQKEKLWEHEKMQEQEKMQEQE-------EKIWEQEKMEKKTQEQEKKTW----D 705
Query: 472 AEKKREELNKMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWE 525
EK REE + E K K+ + + ++Q+++ E + + E EE WE
Sbjct: 706 QEKMREEESMREREK-------KMREEEEMMREQEEKMQEQEEKMQEQEEEMWE 752
Score = 41.6 bits (96), Expect = 0.005
Identities = 76/411 (18%), Positives = 166/411 (40%), Gaps = 42/411 (10%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRY 236
QE + + + R Q Q++ + + +E+D + + K+E + M E + +
Sbjct: 367 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKM 426
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKE--QAATFKLEKNKQGQKEAQ 294
E++ +E+ + K+ ++EEK ER K+ + +E + K++K ++ E +
Sbjct: 427 REEKKMQEQEK--KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 295 EKIRKFQR---EMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAAT 351
EK + QR + E L + + +Q E+ + G+ + EK
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQ-EKMREQE 543
Query: 352 EE--EKDKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWK 409
++ E+++K + + +D R K+ +Q W ++ EK+ +
Sbjct: 544 DQMWEQEEKMRDQEQKMWDQEER-MEKKTQEQEKKTWDQE----------EKMREEERMR 592
Query: 410 CRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEW 469
R + ++ E++++ E+ MQ Q ++ + + Q W
Sbjct: 593 EREKKMREEEEMMRE-----QEEKMQEQEEKMQEQEEKMWEQEEKMQ------EQEEKMW 641
Query: 470 SDAEKKREELNKMETNKPRDLFIAKLLNKLKQQQQQQQQHSENK--------RENSEDPE 521
EK E+ KM + KL K Q+Q++ Q E K ++ E +
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEK 701
Query: 522 ESWENLVSDEDFSALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQL 572
++W+ E+ S E E+ E +R K+Q + +K+ ++ +++
Sbjct: 702 KTWDQEKMREEESMREREKKMREEEEMMREQEEKMQE--QEEKMQEQEEEM 750
Score = 41.2 bits (95), Expect = 0.007
Identities = 69/396 (17%), Positives = 148/396 (37%), Gaps = 43/396 (10%)
Query: 180 EEQQPKSRPKFQSPQIQA-TISPPLQPKTKTYEEDPKSKPKKEEK---------NMEVNM 229
E ++ R KF PQ+Q T+ + + + E K K+EEK E M
Sbjct: 250 ELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKM 309
Query: 230 KE-----WILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLE 284
+E W ++ E+E E K L E+++ E + + + +E+ + E
Sbjct: 310 REQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEE 369
Query: 285 KNKQGQK---EAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNF 341
K + ++ E ++++R+ +++M E+ ++ R++ + + E
Sbjct: 370 KMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREE 429
Query: 342 NLFEKSAAATEEEKDKKKEPHDV-------RNFDYTARSWTGKSPK-------QFLIDWV 387
++ T ++++K +E + R + T R K K Q +W
Sbjct: 430 KKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 489
Query: 388 RKNLPKSPNPSFEKVPV----GRYWKCRVRVIKSED----DVLVVCPTILTEDGMQAQHL 439
++ LP+ +E+ + + W+ ++ E+ + + + E Q
Sbjct: 490 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 549
Query: 440 GATLALYRLVKGQSVHQLLPPTYRDVWLEWSDAEKKREELNKMETNK---PRDLFIAKLL 496
+ ++ T W EK REE E K + + +
Sbjct: 550 EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQE 609
Query: 497 NKLKQQQQQQQQHSENKRENSEDPEESWENLVSDED 532
K+++Q+++ Q+ E E E +E E + E+
Sbjct: 610 EKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEE 645
Score = 37.7 bits (86), Expect = 0.076
Identities = 38/151 (25%), Positives = 75/151 (49%), Gaps = 14/151 (9%)
Query: 171 LPEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPK-KEEKNMEVNM 229
LPE + +E ++ + + K Q + + ++ KT+ E+ + K +EE++M
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719
Query: 230 K-----EWILRYAE---QQNEEEKNENSKSL-EEEEKFDPNERYLHLAAKLLDAKEQAAT 280
K E ++R E Q+ EE+ E + + E+EEK E + +L + KE+
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEK--L 777
Query: 281 FKLEKNKQGQK--EAQEKIRKFQREMETLED 309
++ EK ++ +K E +EK+R + +M E+
Sbjct: 778 WEHEKMQEQEKIWEQEEKMRDQEEKMRGQEE 808
Score = 33.1 bits (74), Expect = 1.9
Identities = 26/137 (18%), Positives = 63/137 (45%), Gaps = 4/137 (2%)
Query: 177 QEFEEQQPKSRPKF--QSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWIL 234
+E EEQ + K Q +++ + + + +E++ K ++E+K + + W
Sbjct: 344 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE-KQMREQEQKMRDQEERMWEQ 402
Query: 235 RYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQ-AATFKLEKNKQGQKEA 293
++ EE E K E+ EK ++ K D +E+ ++ + ++ +E
Sbjct: 403 DERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREE 462
Query: 294 QEKIRKFQREMETLEDH 310
+E +R+ + +M+ E++
Sbjct: 463 EETMREQEEKMQKQEEN 479
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 44.7 bits (104), Expect = 6e-04
Identities = 50/200 (25%), Positives = 85/200 (42%), Gaps = 18/200 (9%)
Query: 181 EQQPKSRPKFQSPQIQATI---SPPLQPKTKTYEEDPKSK-------PKKEEKNMEVNMK 230
+++ KS K +SP+ T+ SP + K P K P KEE K
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAK 800
Query: 231 EWILRYAEQQNEE--EKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQ 288
+ A+ +E +K E ++EEEK P E + K + ++ AT K E+ K
Sbjct: 801 SPLKEDAKAPEKEIPKKEEVKSPVKEEEK--PQEVKVKEPPKKAEEEKAPATPKTEEKKD 858
Query: 289 GQKEAQEKIRKFQREMETLEDHPVFNP---AMKISHQQNERKKPPVATEGESALNFNLFE 345
+KE K + ++E ++ V P ++ ++ E KK E E+ + +
Sbjct: 859 SKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEV-K 917
Query: 346 KSAAATEEEKDKKKEPHDVR 365
+ A E+ + KKEP D +
Sbjct: 918 EDAKPKEKTEVAKKEPDDAK 937
Score = 43.1 bits (100), Expect = 0.002
Identities = 44/185 (23%), Positives = 72/185 (38%), Gaps = 9/185 (4%)
Query: 184 PKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEE 243
P+ PK P + I + K K E+ K EE+ E + E + E++ +E
Sbjct: 423 PEGLPKI--PSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKE 480
Query: 244 EKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKIRKFQRE 303
E+ + + EEEE E K A+E A+ K K+ ++ K +
Sbjct: 481 EEGKEEEGGEEEEAEGGEEE-----TKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEK 535
Query: 304 METLEDHPVFNPAMKISHQQNERKKPPVA--TEGESALNFNLFEKSAAATEEEKDKKKEP 361
E V +P S + E K PP A E E A + + A K++ K P
Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595
Query: 362 HDVRN 366
+ ++
Sbjct: 596 AEAKS 600
Score = 40.0 bits (92), Expect = 0.015
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 14/180 (7%)
Query: 172 PEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKK---EEKNMEVN 228
P+ +E PK+ K S + +A +PK + +E KPK+ E K E
Sbjct: 839 PKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAE 898
Query: 229 MKEWI---LRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEK 285
K+ + + A + E +++ K E K +P++ +K + KE AA K +
Sbjct: 899 DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKE-AAPEKKDT 957
Query: 286 NKQGQKEAQEKIR---KFQREMETLEDHPVFNPAMKI----SHQQNERKKPPVATEGESA 338
++ K+ +EK + K + + +TL P A K S Q + K P ATE ++A
Sbjct: 958 KEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDKAA 1017
Score = 37.4 bits (85), Expect = 0.099
Identities = 52/224 (23%), Positives = 90/224 (40%), Gaps = 32/224 (14%)
Query: 172 PEGFSQEFEEQQP----KSRPKFQSPQIQATISP-----PLQPKTKTYEEDPK----SKP 218
PE S E EE + KS K +SP + SP P + K+ EE P
Sbjct: 562 PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621
Query: 219 KKEEKNMEVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQA 278
KEE +K + + E + E +KS E+EE P + + A+ ++
Sbjct: 622 VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681
Query: 279 ATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESA 338
+ K E + ++A+ +++ + E + +K + E+ K PV E ++
Sbjct: 682 SPVKAE--AKSPEKAKSPVKEEAKSPEKAKS------PVKEEAKSPEKAKSPVKEEAKTP 733
Query: 339 LNFNLFEKSAAATEEE---KDKKKEPHDVRNFDYTARSWTGKSP 379
EK+ + +EE +K K P + D +S K+P
Sbjct: 734 ------EKAKSPVKEEAKSPEKAKSPEKAKTLD--VKSPEAKTP 769
Score = 36.2 bits (82), Expect = 0.22
Identities = 51/200 (25%), Positives = 76/200 (38%), Gaps = 32/200 (16%)
Query: 183 QPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNE 242
+ KS K +SP ++A P + K+ EE P+K + ++ K + + E
Sbjct: 673 EAKSPEKAKSP-VKAEAKSPEKAKSPVKEE--AKSPEKAKSPVKEEAKSPEKAKSPVKEE 729
Query: 243 EEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKL------------EKNKQGQ 290
+ E +KS +EE P + AK LD K A EK K
Sbjct: 730 AKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPV 789
Query: 291 KEAQEKIRKFQR---------EMETLEDHPVFNPAMKISHQQNER-KKPPVATEGESALN 340
KE + K + E E + V +P + Q + K+PP E E A
Sbjct: 790 KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA-- 847
Query: 341 FNLFEKSAAATEEEKDKKKE 360
+ TEE+KD KKE
Sbjct: 848 -----PATPKTEEKKDSKKE 862
Score = 35.0 bits (79), Expect = 0.49
Identities = 38/173 (21%), Positives = 70/173 (40%), Gaps = 16/173 (9%)
Query: 191 QSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSK 250
+ PQ PP + + + PK++ KK+ K E KE A + EEK E +
Sbjct: 828 EKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKE-----APKPKVEEKKEPAV 882
Query: 251 SLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKIRKFQREMETLEDH 310
+E K + + K + E+ A K+E + + + + ++ K +E + +
Sbjct: 883 EKPKESKVEAKKEEAE-DKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAK--KEPDDAKAK 939
Query: 311 PVFNPAMK--ISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKEP 361
PA K + ++ + K+ E + A A E++K KEP
Sbjct: 940 EPSKPAEKKEAAPEKKDTKEEKAKKPEEKP------KTEAKAKEDDKTLSKEP 986
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 43.5 bits (101), Expect = 0.001
Identities = 70/397 (17%), Positives = 157/397 (39%), Gaps = 36/397 (9%)
Query: 191 QSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQNEEEKNENSK 250
+ PQ Q + + K ++ + + ++EE+ + +E LR +++ E+ E +
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERR 322
Query: 251 SLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQ---KEAQEKIRKFQ-REMET 306
+E + R L + + +EQ + E+ ++ Q +E +E+ R+ Q R +
Sbjct: 323 EQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ 382
Query: 307 LEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKEPHDVRN 366
L ++ +Q R++ + E + L + E+E+++ ++ H+
Sbjct: 383 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442
Query: 367 FDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCP 426
R K ++ DW+++ E+ + + ++ + +++
Sbjct: 443 -----REQRLKREQEERRDWLKRE---------EETERHEQERRKQQLKRDQEEERRERW 488
Query: 427 TILTEDGMQAQHLGATLALYR--------LVKGQSVHQLLPPTYRDVWLEWSDAEKKREE 478
L E+ + Q L R +K Q + L R + E++RE+
Sbjct: 489 LKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQ 548
Query: 479 LNKMETNKPRDLFIAKLLNKLKQQQQQQQ--QHSENKREN--SEDPEESWENLVSDEDFS 534
L K E K + + K +Q++++ Q + E +R+ + EE E + E+
Sbjct: 549 LLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 535 ALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQ 571
L E + L+ R+ + Q+LLK +Q
Sbjct: 609 RLEQEERREQRLK------REEPEEERRQQLLKSEEQ 639
Score = 42.0 bits (97), Expect = 0.004
Identities = 39/191 (20%), Positives = 87/191 (45%), Gaps = 6/191 (3%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRY 236
QE E+QQ + R + Q + Q Q + + +E + + ++ E+ + +E +
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQ 350
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQ-E 295
++ EEE+ E E+EE + E+ L +L ++ +L + +Q ++E Q
Sbjct: 351 LRREQEEERREQQLRREQEE--ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 408
Query: 296 KIRKFQREMETLEDHPVFNPAMKISHQQ---NERKKPPVATEGESALNFNLFEKSAAATE 352
+ ++ +RE + + + + H+Q ER++ + E E ++ E+ E
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468
Query: 353 EEKDKKKEPHD 363
+E+ K++ D
Sbjct: 469 QERRKQQLKRD 479
Score = 40.4 bits (93), Expect = 0.012
Identities = 28/142 (19%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Query: 220 KEEKNMEVNMKEWILRYAEQQNEEEKNENSKSL-EEEEKFDPNERYLHLAAKLLDAKEQA 278
+EE+ E +E +LR E++ +EE+ + + L EEEE+ ER + + ++Q
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 279 ATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESA 338
+ ++ ++ Q+E + + ++ +RE + + ++ +Q ER++ + E E
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 339 LNFNLFEKSAAATEEEKDKKKE 360
+ E+ ++E
Sbjct: 359 RREQQLRREQEEERREQQLRRE 380
Score = 40.0 bits (92), Expect = 0.015
Identities = 34/205 (16%), Positives = 96/205 (46%), Gaps = 23/205 (11%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRY 236
++F E++P+ R + + Q++ + + + +E + + +++E++ + +E LR
Sbjct: 1643 RKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRR 1702
Query: 237 AEQQN---EEEKNENSKSLE-------------EEEKFDPNERYLHLAAK--LLDAKEQA 278
E++ +EE+ + LE E+E+ ERY + + L +E+
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 279 ATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESA 338
+ E++++ ++E Q + + ++++ + E F ++ ++ E++ P +G+
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822
Query: 339 LNFNLFEKSAAATEEEKDKKKEPHD 363
+E+ EE++ + ++ D
Sbjct: 1823 -----WEEEQLQLEEQEQRLRQERD 1842
Score = 39.7 bits (91), Expect = 0.020
Identities = 45/211 (21%), Positives = 87/211 (41%), Gaps = 48/211 (22%)
Query: 180 EEQQPKSRP----KFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILR 235
EE+Q SR KF+ + Q + + K EE+ + + ++ K E +E +L+
Sbjct: 1418 EEEQQLSRQERDRKFREEEQQVRRQ---ERERKFLEEEQQLRQERHRKFRE---EEQLLQ 1471
Query: 236 YAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATF-------------- 281
E+Q + + K LEEE++ ER + L ++E F
Sbjct: 1472 EREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQR 1531
Query: 282 -------KLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATE 334
+L + ++GQ+ Q++ RKF+ E + ++ ++S Q+ +RK
Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQE----REEQQLSRQERDRK------- 1580
Query: 335 GESALNFNLFEKSAAATEEEKDKKKEPHDVR 365
F L E+ E+E+ ++ +R
Sbjct: 1581 ------FRLEEQKVRRQEQERKFMEDEQQLR 1605
Score = 39.7 bits (91), Expect = 0.020
Identities = 43/198 (21%), Positives = 85/198 (42%), Gaps = 24/198 (12%)
Query: 173 EGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPK------KEEKNME 226
E QE EEQQ + + + +++ + + K E++ + + + ++E++ +
Sbjct: 1561 EQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRK 1620
Query: 227 VNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKN 286
E +L+ E+Q + + K LEEE + ER L D K + L++
Sbjct: 1621 FREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHD-RDRKFREEEQLLQEG 1679
Query: 287 KQGQKEAQEKIRKFQREMETL----EDHPVFNPAMKISHQQNERKKPPVATEGESALNFN 342
++ Q QE+ RKF+ E + L + ++ Q+ ERK F
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK-------------FR 1726
Query: 343 LFEKSAAATEEEKDKKKE 360
E+ TE+E+ +++E
Sbjct: 1727 EEEQLRQETEQEQLRRQE 1744
Score = 39.3 bits (90), Expect = 0.026
Identities = 39/179 (21%), Positives = 76/179 (42%), Gaps = 21/179 (11%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRY 236
Q+ +Q R + + Q + + K +E+ + K+EE+ E + +E +
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET-ERHEQERRKQQ 475
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEK 296
++ EEE+ E LEEEE+ + ER + ++ ++ Q+E +E+
Sbjct: 476 LKRDQEEERRERWLKLEEEERREQQER------------------REQQLRREQEERREQ 517
Query: 297 IRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEK 355
K Q E E L+ ++ +Q ER++ + E E L E+ +EE+
Sbjct: 518 RLKRQEEEERLQQR--LRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEER 574
Score = 39.3 bits (90), Expect = 0.026
Identities = 34/165 (20%), Positives = 72/165 (43%), Gaps = 8/165 (4%)
Query: 204 QPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQ--QNEEEKNENSKSLEEEEKFDPN 261
Q + EE + + K++E+ + + LR +Q + +EE+ E EEE++ +
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQR---LRSEQQLRREQEERREQLLKREEEKRLEQE 561
Query: 262 ERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQE---KIRKFQREMETLEDHPVFNPAMK 318
R L + + ++Q + E+ +Q K QE + R + E+E LE +K
Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLK 621
Query: 319 ISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKKEPHD 363
+ ER++ + +E + + E++ K++E +
Sbjct: 622 REEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666
Score = 38.9 bits (89), Expect = 0.034
Identities = 35/156 (22%), Positives = 65/156 (41%), Gaps = 9/156 (5%)
Query: 180 EEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQ 239
EE+Q R + + ++ Q + + +D K ++EE+ + ++ R EQ
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437
Query: 240 QNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNK-----QGQKEAQ 294
Q ++ E EE++ R +LL +E+ + E+++ + Q Q
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ 1497
Query: 295 EKIRKFQREMETLEDHP---VFNPAMKISHQQNERK 327
E+ RKF RE E P ++ QQ +RK
Sbjct: 1498 ERDRKF-REQELRSQEPERKFLEEEQQLHRQQRQRK 1532
Score = 37.4 bits (85), Expect = 0.099
Identities = 38/169 (22%), Positives = 70/169 (41%), Gaps = 20/169 (11%)
Query: 168 DDALPEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEV 227
D PE E EEQ+ R +S Q + + E+ + K +++E + +
Sbjct: 1290 DRHFPEEEQLEREEQKEAKRRDRKS-----------QEEKQLLREEREEKRRRQETDRKF 1338
Query: 228 NMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATF-----K 282
+E +L+ E+Q + + K EEE + R + L +E+ F +
Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398
Query: 283 LEKNKQGQKEAQEKIRKFQREMETL----EDHPVFNPAMKISHQQNERK 327
L ++ Q+ Q++ RKF+ E + L D ++ Q+ ERK
Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1447
Score = 37.4 bits (85), Expect = 0.099
Identities = 32/162 (19%), Positives = 71/162 (43%), Gaps = 18/162 (11%)
Query: 173 EGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEW 232
E QE E++Q + + +++ + + P + + +E + + +EE+ + +E
Sbjct: 1729 EQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE--RDRKFREEEQLRQEREEQ 1786
Query: 233 ILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKE 292
LR E + + E + EE++ P +R D K + +L+ +Q Q+
Sbjct: 1787 QLRSQESDRKFREEEQLRQEREEQQLRPQQR---------DGKYRWEEEQLQLEEQEQRL 1837
Query: 293 AQEKIRKFQ-------REMETLEDHPVFNPAMKISHQQNERK 327
QE+ R+++ +E E+ ++ + Q+ ERK
Sbjct: 1838 RQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERK 1879
Score = 36.2 bits (82), Expect = 0.22
Identities = 40/191 (20%), Positives = 85/191 (44%), Gaps = 14/191 (7%)
Query: 178 EFEEQQPKSRPKFQSPQIQATISPPLQPK-TKTY-----EEDPKSKPKKEEKNM----EV 227
E E++Q + R K + P+ Q + + +K Y +E + + ++EEK E+
Sbjct: 687 EEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL 746
Query: 228 NMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNK 287
+E + +QQ EE++ + + + EEK + + L L + +E+ + E+ +
Sbjct: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAE-ERQQ 805
Query: 288 QGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKS 347
+ Q+ E+ K QR + E ++ Q R++ E E L + ++
Sbjct: 806 REQRFLPEEEEKEQRRRQRREREKELQ-FLEEEEQLQRRERAQQLQEEEDGLQED--QER 862
Query: 348 AAATEEEKDKK 358
+ E+ +D+K
Sbjct: 863 RRSQEQRRDQK 873
Score = 36.2 bits (82), Expect = 0.22
Identities = 92/448 (20%), Positives = 170/448 (37%), Gaps = 74/448 (16%)
Query: 177 QEFEE--QQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWIL 234
QE E+ Q+ + R + Q + L+ + K +KP +E ++ ++ +L
Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQE---QLRKEQQLL 906
Query: 235 RYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQ 294
+ E++ + E+ E + E+E ++ E+ L +EQ + EK ++ ++E Q
Sbjct: 907 QEEEEELQREEREKRRRQEQERQYREEEQ-------LQQEEEQLLREEREKRRRQERERQ 959
Query: 295 -------------------EKIRKFQREMETLEDHPVFNPAMKISHQQNE---------- 325
EK R+ +RE + E+ + ++ ++ E
Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Query: 326 -RKKPPVATEGESAL-----NFNLFEKSAAATEEEKDKKKEPHDVRNFDYTARSWTGKSP 379
RKK + E E L L E+ EEE+ +++E + T R
Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR------- 1072
Query: 380 KQFLIDWVRK--NLPKSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCPTILTE--DGMQ 435
+Q L RK L + + P R + R R + E+++ +L E + +
Sbjct: 1073 RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRR 1132
Query: 436 AQHLGATL-----------ALYRLVKGQSVHQLLPPTYR-DVWLEWSDAEKKREELNKME 483
Q L L R + Q L YR + L+ + + REE K
Sbjct: 1133 RQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR 1192
Query: 484 TNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSALSLESANV 543
+ R + L + K++Q+ + + + + +PE+ EN V D E+
Sbjct: 1193 QERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEK--ENAVRDNKVYCKGRENEQF 1250
Query: 544 EDLEPVRNLFRKLQSTPKYQKLLKERQQ 571
LE + R QS Q LL E+Q+
Sbjct: 1251 RQLED--SQLRDRQSQQDLQHLLGEQQE 1276
Score = 36.2 bits (82), Expect = 0.22
Identities = 30/135 (22%), Positives = 61/135 (45%), Gaps = 24/135 (17%)
Query: 173 EGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEW 232
E QE EEQQ +S Q + + E+ + + ++EE+ + ++
Sbjct: 1777 EQLRQEREEQQLRS-----------------QESDRKFREEEQLRQEREEQQLRPQQRDG 1819
Query: 233 ILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQ-- 290
R+ E+Q + E+ E E + ++ E++ A + +E+ ++ E+ K+ Q
Sbjct: 1820 KYRWEEEQLQLEEQEQRLRQERDRQYRAEEQF---ATQEKSRREEQELWQEEEQKRRQER 1876
Query: 291 --KEAQEKIRKFQRE 303
K +E IR+ Q+E
Sbjct: 1877 ERKLREEHIRRQQKE 1891
Score = 35.8 bits (81), Expect = 0.29
Identities = 32/144 (22%), Positives = 63/144 (43%), Gaps = 12/144 (8%)
Query: 168 DDALPEGFSQEF--EEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNM 225
+ L EG Q+ +E+ K R + Q + Q LQ + + ++ + K ++EE+
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQ-- 1730
Query: 226 EVNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEK 285
LR +Q + + E + + EEE+ P L + D K + ++
Sbjct: 1731 --------LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQE 1782
Query: 286 NKQGQKEAQEKIRKFQREMETLED 309
++ Q +QE RKF+ E + ++
Sbjct: 1783 REEQQLRSQESDRKFREEEQLRQE 1806
Score = 33.9 bits (76), Expect = 1.1
Identities = 43/200 (21%), Positives = 82/200 (41%), Gaps = 37/200 (18%)
Query: 173 EGFSQEFEEQ----QPKSRPKFQSPQI--QATISPPLQPKTKTYEEDPKSKPKKEEKNME 226
E QE EEQ Q + R KF+ ++ Q L+ + + ++ + K KEE+ +
Sbjct: 1342 EQLLQEREEQPLRRQERDR-KFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLR 1400
Query: 227 VNMKEWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKN 286
+E LR + E+ + E + KF E+ + +E+ F E+
Sbjct: 1401 CQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVR-------RQERERKFLEEE- 1452
Query: 287 KQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEK 346
Q+ QE+ RKF+ E + L++ ++ Q+ +RK E+
Sbjct: 1453 ---QQLRQERHRKFREEEQLLQE----REEQQLHRQERDRK---------------FLEE 1490
Query: 347 SAAATEEEKDKKKEPHDVRN 366
+E+D+K ++R+
Sbjct: 1491 EQQLRRQERDRKFREQELRS 1510
Score = 33.5 bits (75), Expect = 1.4
Identities = 40/210 (19%), Positives = 84/210 (40%), Gaps = 24/210 (11%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQP-KTKTYEEDPKSKPKKEEKNMEVNMKEWILR 235
Q +E+ + R ++Q + + LQ K EE P + + + +E+ K R
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKG---R 223
Query: 236 YAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKE---------------QAAT 280
+QQ E+ + EEE+++ E L + L +E +
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 281 FKLEKNKQGQKEAQEKIRKFQ-----REMETLEDHPVFNPAMKISHQQNERKKPPVATEG 335
+L + +Q +++ Q+++R+ Q +E E E + QQ ER++ + E
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ 343
Query: 336 ESALNFNLFEKSAAATEEEKDKKKEPHDVR 365
E L + E++ ++++ + R
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEERR 373
Score = 33.5 bits (75), Expect = 1.4
Identities = 75/388 (19%), Positives = 149/388 (38%), Gaps = 53/388 (13%)
Query: 177 QEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRY 236
+E EQQ + + + Q Q L+ + + E + ++ + ++ ++ + R
Sbjct: 370 EERREQQLRREQQLRREQ-QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEK 296
E++ E+K+E + E+ K + ER L +E+ + E+ KQ K QE+
Sbjct: 429 QEEERHEQKHEQERR-EQRLKREQEER-----RDWLKREEETERHEQERRKQQLKRDQEE 482
Query: 297 IRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKD 356
R+ +R ++ E+ +Q ER++ + E E L K E +
Sbjct: 483 ERR-ERWLKLEEEE---------RREQQERREQQLRREQEERREQRL--KRQEEEERLQQ 530
Query: 357 KKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIK 416
+ + +R R K ++ ++ R+ E+ + R +++K
Sbjct: 531 RLRSEQQLRREQEERREQLLKREEEKRLEQERR----------EQRLKREQEERRDQLLK 580
Query: 417 SEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPPTYRDVWLEWSD-AEKK 475
E+ E Q L + +K + V +L R+ L+ + E++
Sbjct: 581 REE-----------ERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629
Query: 476 REELNKMETNKPRDLFIAKLLNKLKQQQQQQQQHSENKRENSEDPEESWENLVSDEDFSA 535
R++L K E + R +QQ +++QQ +R E+ EE E + E
Sbjct: 630 RQQLLKSEEQEER----------RQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 536 LSLESANVEDLEPVRNLFRKLQSTPKYQ 563
+ E+ E R R PK+Q
Sbjct: 680 RREQELAEEEQEQARE--RIKSRIPKWQ 705
Score = 33.5 bits (75), Expect = 1.4
Identities = 30/143 (20%), Positives = 64/143 (44%), Gaps = 10/143 (6%)
Query: 173 EGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEW 232
E QE +Q R + + + Q + Q + + + + + ++E++ +E
Sbjct: 608 ERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEER 667
Query: 233 ILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKL-------LDAKEQAATFKLEK 285
+ + ++++EEE+ E + L EEE+ ER K DA+ Q+ + +
Sbjct: 668 LEQRLKREHEEERRE--QELAEEEQEQARERIKSRIPKWQWQLESEADAR-QSKVYSRPR 724
Query: 286 NKQGQKEAQEKIRKFQREMETLE 308
++GQ+ QE+ K +R L+
Sbjct: 725 KQEGQRRRQEQEEKRRRRESELQ 747
Score = 33.1 bits (74), Expect = 1.9
Identities = 30/158 (18%), Positives = 73/158 (46%), Gaps = 12/158 (7%)
Query: 180 EEQQPKSRPKFQS-PQIQATISPPLQPKTKTYEEDP--KSKPKKEEKNMEVNMKEWILRY 236
EE+ + R + + P ++ L+ + + E + +KE++ + +E L++
Sbjct: 774 EEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQF 833
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEA--- 293
E++ + ++ E ++ L+EEE D + ++Q ++LE+ ++ ++
Sbjct: 834 LEEEEQLQRRERAQQLQEEE--DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYA 891
Query: 294 ----QEKIRKFQREMETLEDHPVFNPAMKISHQQNERK 327
QE++RK Q+ ++ E+ K Q+ ER+
Sbjct: 892 KPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ 929
Score = 32.0 bits (71), Expect = 4.2
Identities = 40/191 (20%), Positives = 79/191 (41%), Gaps = 21/191 (10%)
Query: 177 QEFEEQ------QPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMK 230
Q+ EEQ Q ++ K + + + + PPL+ + + + + +++ E K
Sbjct: 758 QQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEK 817
Query: 231 EWILRYAEQQNEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQ 290
E ++ E+ + + LEEEE+ ER A+ L +E E+ + +
Sbjct: 818 E-----QRRRQRREREKELQFLEEEEQLQRRER-----AQQLQEEEDGLQEDQERRRSQE 867
Query: 291 KEAQEKIRKFQREMETLEDHPVF-NPAMKISHQQNERKKPPVATEGESALNFNLFEKSAA 349
+ +K R E H ++ PA+ Q+ RK+ + E E L EK
Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPAL----QEQLRKEQQLLQEEEEELQREEREKRRR 923
Query: 350 ATEEEKDKKKE 360
+E + +++E
Sbjct: 924 QEQERQYREEE 934
Score = 32.0 bits (71), Expect = 4.2
Identities = 33/163 (20%), Positives = 76/163 (46%), Gaps = 23/163 (14%)
Query: 180 EEQQPKSRP---KFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRY 236
EEQQ + + KF+ ++++ +P+ K EE+ + ++++ + +E LR
Sbjct: 1490 EEQQLRRQERDRKFREQELRSQ-----EPERKFLEEEQQLH--RQQRQRKFLQEEQQLRR 1542
Query: 237 AEQQNEEEKNENSKSLEEEEKFDPNE----------RYLHLAAKLLDAKEQAATFKLEKN 286
E+ + ++ + K EEE+ E R L + + +EQ F ++
Sbjct: 1543 QERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQ 1602
Query: 287 KQGQKEAQEKIRKFQREMETLEDHPVF--NPAMKISHQQNERK 327
+ ++E Q+++R+ +R+ + ED + ++ Q+ +RK
Sbjct: 1603 QLRRQEGQQQLRQ-ERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Score = 31.2 bits (69), Expect = 7.1
Identities = 25/118 (21%), Positives = 51/118 (43%), Gaps = 18/118 (15%)
Query: 468 EWSDAEKKREELNKMETNKP--------------RDLFIAKLLNKLKQQQQQQQQHSENK 513
EW + E++R E ++++ K R+L + + ++QQQ++++
Sbjct: 179 EWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVF 238
Query: 514 RENSEDPEESWENLVSDEDFSALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQ 571
+E E E ++ E+ E +L+ RKL+ Q+L +ERQ+
Sbjct: 239 QEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER----QELRRERQE 292
Score = 30.8 bits (68), Expect = 9.3
Identities = 34/170 (20%), Positives = 72/170 (42%), Gaps = 26/170 (15%)
Query: 204 QPKTKTYEEDP--KSKPKKEEKNMEV-------NMKEWILRYAEQQNEEEKNENSKSLEE 254
+P+ + EE+P + + K++E+ E+ +E + + Q+ +EE + +E
Sbjct: 123 EPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE 182
Query: 255 EEKFDPNERYL-----HLAAKLLDAKEQAATFKLEKNKQGQKEAQEKIRKFQREMETLED 309
E+ E L H + D ++ LE ++G++E Q++ R+ Q + E+
Sbjct: 183 REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242
Query: 310 HPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEEKDKKK 359
++ RK+ V + E L ++ EEE+ +K
Sbjct: 243 ------------EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRK 280
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,768,863
Number of Sequences: 37866
Number of extensions: 2407966
Number of successful extensions: 17934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 91
Number of HSP's successfully gapped in prelim test: 535
Number of HSP's that attempted gapping in prelim test: 14005
Number of HSP's gapped (non-prelim): 3194
length of query: 1369
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1254
effective length of database: 13,892,928
effective search space: 17421731712
effective search space used: 17421731712
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.