BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens] (1834 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens] 3693 0.0 gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 55 6e-07 gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 55 8e-07 gi|115430108 rho-related BTB domain containing 3 [Homo sapiens] 50 3e-05 gi|150418009 transforming, acidic coiled-coil containing protein... 49 3e-05 gi|45827755 transforming, acidic coiled-coil containing protein ... 49 3e-05 gi|45827753 transforming, acidic coiled-coil containing protein ... 49 3e-05 gi|11119414 transforming, acidic coiled-coil containing protein ... 49 3e-05 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 49 4e-05 gi|40807477 retinoic acid induced 1 [Homo sapiens] 49 4e-05 gi|19924099 synapsin I isoform Ia [Homo sapiens] 48 1e-04 gi|91982772 mucin 17 [Homo sapiens] 48 1e-04 gi|164419758 bromodomain containing 2 [Homo sapiens] 47 1e-04 gi|4826806 bromodomain containing 2 [Homo sapiens] 47 1e-04 gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sa... 47 2e-04 gi|4557445 regulator of chromosome condensation and BTB domain c... 46 3e-04 gi|211904190 hypothetical protein LOC149478 [Homo sapiens] 45 6e-04 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 45 8e-04 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 45 8e-04 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 45 8e-04 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 45 8e-04 gi|95147555 microtubule-associated protein 1A [Homo sapiens] 44 0.001 gi|19924097 synapsin I isoform Ib [Homo sapiens] 44 0.001 gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] 44 0.001 gi|4507161 SRY-box 11 [Homo sapiens] 44 0.001 gi|239743602 PREDICTED: hypothetical protein XP_002342903 [Homo ... 44 0.002 gi|239743600 PREDICTED: hypothetical protein XP_002342902 [Homo ... 44 0.002 gi|239743598 PREDICTED: hypothetical protein XP_002342901 [Homo ... 44 0.002 gi|239743596 PREDICTED: hypothetical protein XP_002342900 [Homo ... 44 0.002 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 44 0.002 >gi|63252863 BTB (POZ) domain containing 12 [Homo sapiens] Length = 1834 Score = 3693 bits (9577), Expect = 0.0 Identities = 1834/1834 (100%), Positives = 1834/1834 (100%) Query: 1 MKLSVNEAQLGFYLGSLSHLSACPGIDPRSSEDQPESLKTGQMMDESDEDFKELCASFFQ 60 MKLSVNEAQLGFYLGSLSHLSACPGIDPRSSEDQPESLKTGQMMDESDEDFKELCASFFQ Sbjct: 1 MKLSVNEAQLGFYLGSLSHLSACPGIDPRSSEDQPESLKTGQMMDESDEDFKELCASFFQ 60 Query: 61 RVKKHGIKEVSGERKTQKAASNGTQIRSKLKRTKQTATKTKTLQGPAEKKPPSGSQAPRT 120 RVKKHGIKEVSGERKTQKAASNGTQIRSKLKRTKQTATKTKTLQGPAEKKPPSGSQAPRT Sbjct: 61 RVKKHGIKEVSGERKTQKAASNGTQIRSKLKRTKQTATKTKTLQGPAEKKPPSGSQAPRT 120 Query: 121 KKQRVTKWQASEPAHSVNGEGGVLASAPDPPVLRETAQNTQTGNQQEPSPNLSREKTREN 180 KKQRVTKWQASEPAHSVNGEGGVLASAPDPPVLRETAQNTQTGNQQEPSPNLSREKTREN Sbjct: 121 KKQRVTKWQASEPAHSVNGEGGVLASAPDPPVLRETAQNTQTGNQQEPSPNLSREKTREN 180 Query: 181 VPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQQFKRADPERLRHASEECSLEAAREEN 240 VPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQQFKRADPERLRHASEECSLEAAREEN Sbjct: 181 VPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQQFKRADPERLRHASEECSLEAAREEN 240 Query: 241 VPKDPQEEMMAGNVYGLGPPAPESDAAVALTLQQEFARVGASAHDDSLEEKGLFFCQICQ 300 VPKDPQEEMMAGNVYGLGPPAPESDAAVALTLQQEFARVGASAHDDSLEEKGLFFCQICQ Sbjct: 241 VPKDPQEEMMAGNVYGLGPPAPESDAAVALTLQQEFARVGASAHDDSLEEKGLFFCQICQ 300 Query: 301 KNLSAMNVTRREQHVNRCLDEAEKTLRPSVPQIPECPICGKPFLTLKSRTSHLKQCAVKM 360 KNLSAMNVTRREQHVNRCLDEAEKTLRPSVPQIPECPICGKPFLTLKSRTSHLKQCAVKM Sbjct: 301 KNLSAMNVTRREQHVNRCLDEAEKTLRPSVPQIPECPICGKPFLTLKSRTSHLKQCAVKM 360 Query: 361 EVGPQLLLQAVRLQTAQPEGSSSPPMFSFSDHSRGLKRRGPTSKKEPRKRRKVDEAPSED 420 EVGPQLLLQAVRLQTAQPEGSSSPPMFSFSDHSRGLKRRGPTSKKEPRKRRKVDEAPSED Sbjct: 361 EVGPQLLLQAVRLQTAQPEGSSSPPMFSFSDHSRGLKRRGPTSKKEPRKRRKVDEAPSED 420 Query: 421 LLVAMALSRSEMEPGAAVPALRLESAFSERIRPEAENKSRKKKPPVSPPLLLVQDSETTG 480 LLVAMALSRSEMEPGAAVPALRLESAFSERIRPEAENKSRKKKPPVSPPLLLVQDSETTG Sbjct: 421 LLVAMALSRSEMEPGAAVPALRLESAFSERIRPEAENKSRKKKPPVSPPLLLVQDSETTG 480 Query: 481 RQIEDRVALLLSEEVELSSTPPLPASRILKEGWERAGQCPPPPERKQSFLWEGSALTGAW 540 RQIEDRVALLLSEEVELSSTPPLPASRILKEGWERAGQCPPPPERKQSFLWEGSALTGAW Sbjct: 481 RQIEDRVALLLSEEVELSSTPPLPASRILKEGWERAGQCPPPPERKQSFLWEGSALTGAW 540 Query: 541 AMEDFYTARLVPPLVPQRPAQGLMQEPVPPLVPPEHSELSERRSPALHGTPTAGCGSRGP 600 AMEDFYTARLVPPLVPQRPAQGLMQEPVPPLVPPEHSELSERRSPALHGTPTAGCGSRGP Sbjct: 541 AMEDFYTARLVPPLVPQRPAQGLMQEPVPPLVPPEHSELSERRSPALHGTPTAGCGSRGP 600 Query: 601 SPSASQREHQALQDLVDLAREGLSASPWPGSGGLAGSEGTAGLDVVPGGLPLTGFVVPSQ 660 SPSASQREHQALQDLVDLAREGLSASPWPGSGGLAGSEGTAGLDVVPGGLPLTGFVVPSQ Sbjct: 601 SPSASQREHQALQDLVDLAREGLSASPWPGSGGLAGSEGTAGLDVVPGGLPLTGFVVPSQ 660 Query: 661 DKHPDRGGRTLLSLGLLVADFGAMVNNPHLSDVQFQTDSGEVLYAHKFVLYARCPLLIQY 720 DKHPDRGGRTLLSLGLLVADFGAMVNNPHLSDVQFQTDSGEVLYAHKFVLYARCPLLIQY Sbjct: 661 DKHPDRGGRTLLSLGLLVADFGAMVNNPHLSDVQFQTDSGEVLYAHKFVLYARCPLLIQY 720 Query: 721 VNNEGFSAVEDGVLTQRVLLGDVSTEAARTFLHYLYTADTGLPPGLSSELSSLAHRFGVS 780 VNNEGFSAVEDGVLTQRVLLGDVSTEAARTFLHYLYTADTGLPPGLSSELSSLAHRFGVS Sbjct: 721 VNNEGFSAVEDGVLTQRVLLGDVSTEAARTFLHYLYTADTGLPPGLSSELSSLAHRFGVS 780 Query: 781 ELVHLCEQVPIATDSEGKPWEEKEAENCESRAENFQELLRSMWADEEEEAETLLKSKDHE 840 ELVHLCEQVPIATDSEGKPWEEKEAENCESRAENFQELLRSMWADEEEEAETLLKSKDHE Sbjct: 781 ELVHLCEQVPIATDSEGKPWEEKEAENCESRAENFQELLRSMWADEEEEAETLLKSKDHE 840 Query: 841 EDQENVNEAEMEEIYEFAATQRKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQW 900 EDQENVNEAEMEEIYEFAATQRKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQW Sbjct: 841 EDQENVNEAEMEEIYEFAATQRKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQW 900 Query: 901 DKVEEMEPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSSCSS 960 DKVEEMEPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSSCSS Sbjct: 901 DKVEEMEPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSSCSS 960 Query: 961 PSRDCQAERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQSGAVRERGLEVSH 1020 PSRDCQAERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQSGAVRERGLEVSH Sbjct: 961 PSRDCQAERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQSGAVRERGLEVSH 1020 Query: 1021 RLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPS 1080 RLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPS Sbjct: 1021 RLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPS 1080 Query: 1081 KQKRDRSILTLSKEPGHQKGKERRSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSRSQK 1140 KQKRDRSILTLSKEPGHQKGKERRSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSRSQK Sbjct: 1081 KQKRDRSILTLSKEPGHQKGKERRSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSRSQK 1140 Query: 1141 SSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFSIIDVDAD 1200 SSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFSIIDVDAD Sbjct: 1141 SSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFSIIDVDAD 1200 Query: 1201 QEPSQSPPRSEAVLQQEDEGALPENRGSLGRRGAPWLFCDRESSPSEASTTDTSWLVPAT 1260 QEPSQSPPRSEAVLQQEDEGALPENRGSLGRRGAPWLFCDRESSPSEASTTDTSWLVPAT Sbjct: 1201 QEPSQSPPRSEAVLQQEDEGALPENRGSLGRRGAPWLFCDRESSPSEASTTDTSWLVPAT 1260 Query: 1261 PLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNREGNEVAQKFSVIRPQTPPPQT 1320 PLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNREGNEVAQKFSVIRPQTPPPQT Sbjct: 1261 PLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNREGNEVAQKFSVIRPQTPPPQT 1320 Query: 1321 PSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISGDRAHFSRRFLKHSPPG 1380 PSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISGDRAHFSRRFLKHSPPG Sbjct: 1321 PSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISGDRAHFSRRFLKHSPPG 1380 Query: 1381 PSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDH 1440 PSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDH Sbjct: 1381 PSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDH 1440 Query: 1441 WNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGN 1500 WNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGN Sbjct: 1441 WNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGN 1500 Query: 1501 SRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPI 1560 SRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPI Sbjct: 1501 SRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPI 1560 Query: 1561 TPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPL 1620 TPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPL Sbjct: 1561 TPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPL 1620 Query: 1621 LQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITPPSR 1680 LQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITPPSR Sbjct: 1621 LQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITPPSR 1680 Query: 1681 SPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGEEEGEGEV 1740 SPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGEEEGEGEV Sbjct: 1681 SPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGEEEGEGEV 1740 Query: 1741 SASQAAVQAADTDEALRCYIRSKPALYQKVLLYQPFELRELQAELRQNGLRVSSRRLLDF 1800 SASQAAVQAADTDEALRCYIRSKPALYQKVLLYQPFELRELQAELRQNGLRVSSRRLLDF Sbjct: 1741 SASQAAVQAADTDEALRCYIRSKPALYQKVLLYQPFELRELQAELRQNGLRVSSRRLLDF 1800 Query: 1801 LDTHCITFTTAATRREKLQGRRRQPRGKKKVERN 1834 LDTHCITFTTAATRREKLQGRRRQPRGKKKVERN Sbjct: 1801 LDTHCITFTTAATRREKLQGRRRQPRGKKKVERN 1834 >gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] Length = 2089 Score = 55.1 bits (131), Expect = 6e-07 Identities = 181/943 (19%), Positives = 318/943 (33%), Gaps = 141/943 (14%) Query: 826 EEEEAETLLKSKDHEEDQENVNEAEMEEIYEFAATQRKLLQEERAAGAGEDADWLEGGSP 885 E ++ K H+ E N+ +++ + A L+E + D E G+ Sbjct: 528 EVPPGSAIIHIKKHQVSVEGTNQTDVKAVGGPAKLLVVSLEEAWPLHGDCETD-AEEGTS 586 Query: 886 VSGQLLAGVQVQKQWDKVEEMEPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAP- 944 ++ ++A V+ + P +A W L + GA+G Sbjct: 587 LTASVVADVRKSQL-----------PAEGDAGAEW---AAAVLKQERAHEVGAQGGPPVA 632 Query: 945 --EQEAP------------EEALGHSSCSSPSRD-----CQAERKE---GSLPHSDDAGD 982 EQ+ P + LG S+ P R+ ER++ G+ D+ GD Sbjct: 633 QVEQDLPISRENLTDLVVDTDTLGEST--QPQREGAQVPTGREREQHVGGTKDSEDNYGD 690 Query: 983 YEQL-------FSSTQGEISEPSQITSEPEEQSGAVRERGLEVSHRL--------APWQA 1027 E L F QG + + EP + + L SH PW+ Sbjct: 691 SEDLDLQATQCFLENQG-LEAVQSMEDEPTQAFMLTPPQELGPSHCSFQTTGTLDEPWEV 749 Query: 1028 SPPHPCRFLLGPPQGGSPRGSH-HTSGSSLSTPRSRGGTSQVGSPTLLSPAVPSKQKRDR 1086 P P +H G LS PR+ G SP P + R Sbjct: 750 LATQPFCLRESEDSETQPFDTHLEAYGPCLSPPRAIPGDQHPESPVHTEPMGIQGRGRQT 809 Query: 1087 --SILTLSKEPGHQKGKERRSVLECRNKGVLMFPEKSPSI----DLTQSNPDHS------ 1134 ++ + KE + G ER + K + PE+ + +LT+ D Sbjct: 810 VDKVMGIPKETAERVGPERGPLERETEK---LLPERQTDVTGEEELTKGKQDREQKQLLA 866 Query: 1135 -------SSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLEEKKALEISPR 1187 S ++ +S+S + + + + +++ EE++ +Q + +++ S E + ++ R Sbjct: 867 RDTQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANR 926 Query: 1188 SCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRGAPWLFCDRESSPSE 1247 C+ E + P+ +L+++ + PE GS ++G + SSP+ Sbjct: 927 ECD---------PAELEEKVPK--VILERDTQRGEPEG-GSQDQKG-------QASSPTP 967 Query: 1248 ASTTDTSWLVPAT--PLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNREGNEVA 1305 L T P+ S S+ + +S R + + P A +R A Sbjct: 968 EPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGL--LNCKMPPAEKASR--IRAA 1023 Query: 1306 QKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISGD 1365 +K S ++P +CL P P ++ S S+ H P SPL P Sbjct: 1024 EKVS-----RGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLP------ 1072 Query: 1366 RAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIP-ID 1424 K G + P E+ + ++ + +++R P + P Sbjct: 1073 --SIKPTVRKTRQDGSQEAPEAPLSS--ELEPFHPKPKIRTRKSSRMTPFPATSAAPEPH 1128 Query: 1425 DCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCTT 1484 +P++P P RT S +P + A + + P P+ T+ Sbjct: 1129 PSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVVPTAPELQ----PSTSTDQPVTSEPTS 1184 Query: 1485 QRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLET 1544 Q KS S + + + +AL RP + P +Q + G + ++T Sbjct: 1185 QVTRGRKSR---SSVKTPETVVPTALELQPSTSTDRPVTSEPTSQ--ATRGRKNRSSVKT 1239 Query: 1545 PKGANRKKNLPPKVPITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQ 1604 P+ P VP P Q S + E R R V + + + Sbjct: 1240 PE---------PVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRSSVKTPEPVVPTAPE 1290 Query: 1605 TLDSDSEDESQSSQPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKG 1664 S S D + +P + +T S P V E +P P T Sbjct: 1291 LRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETV-VPTAPELQISTSTDQPVTPKPTSR 1349 Query: 1665 PRHQRKHHESI-TPPSRSP-TKEAPPGLNDDAQIPASQESVAT 1705 R + S+ P S P E PP + + + S AT Sbjct: 1350 TTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRAT 1392 Score = 36.6 bits (83), Expect = 0.23 Identities = 50/196 (25%), Positives = 77/196 (39%), Gaps = 39/196 (19%) Query: 30 SSEDQPESLKTGQMMDESDEDFKELCASFFQRVKKHGIKEVSGERKTQKAASNGTQIRSK 89 S E ESLK + E+ E+ +E ++V+K + + ER+ ++ +N ++ Sbjct: 882 SPERDRESLK---VEIETSEEIQE------KQVQKQTLPSKAFEREVERPVANRECDPAE 932 Query: 90 LK-RTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVL---A 145 L+ + + + T +G +P GSQ K QAS P G L Sbjct: 933 LEEKVPKVILERDTQRG----EPEGGSQDQ--------KGQASSPTPEPGVGAGDLPGPT 980 Query: 146 SAPDP----------PVLRETAQNTQTGNQQEPSPNLSREKTRENVPNSDSQPPPSCLTT 195 SAP P PV Q + P+ SR + E V D + P +CL Sbjct: 981 SAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQESPDACLPP 1040 Query: 196 AVPS----PSKPRTAQ 207 VP P KP +Q Sbjct: 1041 TVPEAPAPPQKPLNSQ 1056 Score = 36.6 bits (83), Expect = 0.23 Identities = 111/548 (20%), Positives = 188/548 (34%), Gaps = 92/548 (16%) Query: 1060 RSRGGTSQVGSPTLLSPAVPSKQKRDRSILTLSKEPGHQ--KGKERRSVLECRNKGVLMF 1117 R R S +P L P P + + ++ EP Q +G+ RS ++ V Sbjct: 1393 RGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTA 1452 Query: 1118 PEKSPSIDLTQ---SNPDHSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISSD 1174 PE PS Q P ++R + S + + V+ + EL+ + + ++S+ Sbjct: 1453 PELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVV---PTAPELQASASTDQPVTSE 1509 Query: 1175 PLEEKKALEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRGA 1234 P + S + + V A E S + V + P +R + GR Sbjct: 1510 PTSRTTRGRKNRSSVKTPETV-VPAAPELQPSTSTDQPVTPE------PTSRATRGR--- 1559 Query: 1235 PWLFCDRESSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRA 1294 ++ S T ++ +VP P + Q S+ R+ L T R Sbjct: 1560 --------TNRSSVKTPES--IVPIAP----------ELQPSTSRNQLVTPEPTSRATRC 1599 Query: 1295 SVGNREGNEVAQKFSVIRPQTPPPQTPSSCLTPVSPGTSD--GRRQGHRSPSRPHPGGHP 1352 NR + + + P P P +S PV+P + RR+ +RS + P Sbjct: 1600 RT-NRSSVKTPEP---VVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEP 1655 Query: 1353 HSSPLAPHP-----------ISGDRAHFSRRFLKHSPP--------GPSFLNQTPAGEVV 1393 +S L P G ++ R + P P +Q + E + Sbjct: 1656 AASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPI 1715 Query: 1394 EVGDSDDEQEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPID-HWNLERTGPLSTS 1452 Q A + + + P+D P C +EP S + W R T+ Sbjct: 1716 TQPSCIKRQRAAGNPGSLAAPIDHKP------CSAPLEPKSQASRNQRWGAVRAAESLTA 1769 Query: 1453 SPSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWD 1512 P + SP LL+ TPI S + + +S L +L Sbjct: 1770 IP-----------EPASPQLLE-TPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLAT 1817 Query: 1513 VWDGEEQRPPETPPPAQM------PSAGGAQKP---EGLETPKGANRKKNLPPKVPITPM 1563 + Q+ P+ +Q A+KP E + TPK RK++ + P + Sbjct: 1818 MDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPKPGKRKRDQAEEEP-NRI 1876 Query: 1564 PQYSIMET 1571 P S+ T Sbjct: 1877 PSRSLRRT 1884 Score = 35.8 bits (81), Expect = 0.39 Identities = 84/409 (20%), Positives = 137/409 (33%), Gaps = 52/409 (12%) Query: 92 RTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDPP 151 R +QT K + P E G + R +R T+ E V GE + D Sbjct: 805 RGRQTVDKVMGI--PKETAERVGPE--RGPLERETEKLLPERQTDVTGEEELTKGKQDRE 860 Query: 152 ----VLRETAQNTQTGNQQEPSPNLSREKTRENVPNSDSQPPPSCLTTAVPSPSKPRTAQ 207 + R+T + N + SP RE + + S+ +PS + R Sbjct: 861 QKQLLARDTQRQESDKNGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFERE-- 918 Query: 208 LVLQRMQQFKRADPERLRHASEECSLEAAREENVPKDPQEEMMAGNVYGLGPPAPESDAA 267 ++R + DP L + LE + P+ ++ P PE Sbjct: 919 --VERPVANRECDPAELEEKVPKVILERDTQRGEPEGGSQDQKG----QASSPTPEPGVG 972 Query: 268 VALTLQQEFARVGASAHDDS--------LEEKGLFFCQI-----CQKNLSAMNVTRREQH 314 A V + + +KGL C++ + +A V+R +Q Sbjct: 973 AGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMPPAEKASRIRAAEKVSRGDQ- 1031 Query: 315 VNRCLDEAEKTLRPSVPQIPECPICGKPFLTLKSRTSHLKQCAVKMEVGPQLLLQAVRLQ 374 + + L P+VP+ P P KP L S++ K A + P L ++ Sbjct: 1032 -----ESPDACLPPTVPEAPAPP--QKP---LNSQSQ--KHLAPPPLLSPLLPSIKPTVR 1079 Query: 375 TAQPEGSSSPPMFSFSDHSRGLKRRGPTSKKEPRKRRKVDEAPSEDLLVAMALSRSEMEP 434 + +GS P S L+ P K RK ++ P+ S S +P Sbjct: 1080 KTRQDGSQEAPEAPLSSE---LEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQP 1136 Query: 435 GAAVPALRLESAFSERIRPEAENKSRKKKPPVSPPLLLVQDSETTGRQI 483 P S+ R S K PV P +Q S +T + + Sbjct: 1137 VTPKPT-------SQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPV 1178 Score = 35.4 bits (80), Expect = 0.51 Identities = 37/144 (25%), Positives = 59/144 (40%), Gaps = 18/144 (12%) Query: 147 APDPPVLRETAQNT-QTGNQQEPSPNLSRE----------KTREN-----VPNSDSQPPP 190 +P P ++ T + T Q G+Q+ P LS E +TR++ P + + P P Sbjct: 1068 SPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEP 1127 Query: 191 SCLT-TAVPSPSKPRTAQLVLQRMQQFKRADPERLRHASEECSLEAAREENVPKDPQEEM 249 T TA P KP T+Q R + PE + + E + ++ V +P ++ Sbjct: 1128 HPSTSTAQPVTPKP-TSQATRSRTNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTSQV 1186 Query: 250 MAGNVYGLGPPAPESDAAVALTLQ 273 G PE+ AL LQ Sbjct: 1187 TRGRKSRSSVKTPETVVPTALELQ 1210 Score = 33.9 bits (76), Expect = 1.5 Identities = 27/107 (25%), Positives = 46/107 (42%), Gaps = 5/107 (4%) Query: 1051 TSGSSLSTPRSRGGTSQVGSPTLLSPAVPSKQKRDRSILTLSKEPGHQ--KGKERRSVLE 1108 TS + T R R S V +P + PA P Q + ++ EP + +G+ RS ++ Sbjct: 1507 TSEPTSRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVK 1566 Query: 1109 CRNKGVLMFPEKSPSI---DLTQSNPDHSSSRSQKSSSKLNEEDEVI 1152 V + PE PS L P ++R + + S + + V+ Sbjct: 1567 TPESIVPIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVV 1613 >gi|149158690 HLA-B associated transcript-2 [Homo sapiens] Length = 2157 Score = 54.7 bits (130), Expect = 8e-07 Identities = 127/562 (22%), Positives = 195/562 (34%), Gaps = 94/562 (16%) Query: 898 KQWDKVEEMEPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSS 957 +Q DK L+ R+ AA E LP A AP PEEAL + Sbjct: 1249 QQQDKPPRFRRLKQERENAARGSEGKPSLTLP-----------ASAP---GPEEALTTVT 1294 Query: 958 CSSPSRDCQAERKEGSLPHSDDAGDYEQLFSST-------QGEISEPSQITSEPEE---- 1006 + R A+ + S +SD A + + S + +G+ P + P+ Sbjct: 1295 VAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTP 1354 Query: 1007 --------------QSGAVRERGLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGSHHTS 1052 G + +R ++S R + + P R P GG S +S Sbjct: 1355 GGGGGGAVPGISAMSRGDLSQRAKDLSKR--SFSSQRPGMERQNRRPGPGGKAGSSGSSS 1412 Query: 1053 GSSLSTPRSRGGTSQVGSPTLLSPAVPSKQKRDRSI-LTLSKEPGHQKGKERRSVLECRN 1111 G P R G + + SP S+ +R L L P R + N Sbjct: 1413 GGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSN 1472 Query: 1112 -----KGVLMFPEKSPSIDLTQSNPDHSSSRSQKSSSKLN------EEDEVILLLDSDEE 1160 + + + S+ +P H Q E V L SD Sbjct: 1473 PAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQRVNSGLSSDPH 1532 Query: 1161 LELEQTKMKSISSDPLEEK-------KALEISPRSCELFSIIDVDADQEPSQSPPRSEAV 1213 E ++ + P + K E PR EL QE S PP S Sbjct: 1533 FEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELL--------QEESLPPPHSSGF 1584 Query: 1214 LQQEDEGALP--ENRGSLGRRGAPWLFCDRESSPSEASTTDTS---WLVPATPLASRSRD 1268 L + EG P E+R + P ++ ++ S S +S W+ P +P Sbjct: 1585 LGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFED---- 1640 Query: 1269 CSSQTQISSLRSGLAVQAVTQHT--PRASVGNREGN-EVAQKFSVIRPQTPPPQTPSSCL 1325 + T++S SG+ + +Q + P + + +G + A + RP P C Sbjct: 1641 -VAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCE 1699 Query: 1326 TPVSPGTSDGRRQGHRSPSRPHPGGH---PHSSPLAPHPISGDRAHFSRRFLKHSPPGPS 1382 P PG+ RR P PH G P PL P PI +R S+R + + PGP Sbjct: 1700 GP--PGSEPPRRP----PPAPHDGDRKELPREQPLPPGPIGTER---SQRTDRGTEPGPI 1750 Query: 1383 FLNQTPAGEVVEVGDSDDEQEV 1404 + P G V+ G SD + ++ Sbjct: 1751 RPSHRP-GPPVQFGTSDKDSDL 1771 Score = 34.3 bits (77), Expect = 1.1 Identities = 56/237 (23%), Positives = 82/237 (34%), Gaps = 39/237 (16%) Query: 1525 PPPAQMPSAGGAQKPEGLETPKGANR-------KKNLPPKVPITPMPQYSIMETPVLKK- 1576 PP P G Q P TP G +R + + PP + P+ + SI++ LK+ Sbjct: 256 PPYLPFPPPYGPQGPYRYPTPDGPSRFPRVAGPRGSGPPMRLVEPVGRPSILKEDNLKEF 315 Query: 1577 -ELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDE-------SQSSQPLLQAPHC-- 1626 +LD+ + E +++ + DS++E SQS+ + P Sbjct: 316 DQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSDEEGAEGHRDSQSASGEERPPEADG 375 Query: 1627 ---QTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPT 1683 + S+ P A + T PG PK P + PP R P Sbjct: 376 KKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPP---------------LPPPHRGPA 420 Query: 1684 KE-APPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGEEEGEGE 1739 PPG D P + D + QSSS E A E A E E Sbjct: 421 GNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSS--EISLAVERARRRREEEE 475 Score = 32.0 bits (71), Expect = 5.7 Identities = 65/266 (24%), Positives = 95/266 (35%), Gaps = 49/266 (18%) Query: 401 PTSKKEPRKRRKVDEAPSEDLLVAMALSRSEMEPGAAVPALRLESAFSERIRPEAENKSR 460 P P+K PS++ L + ++ PG P R S + E + R Sbjct: 1188 PAKSLAPKKPPTGPLPPSKEPL------KEKLIPGPLSPVARGGSNGGSNVGMEDGERPR 1241 Query: 461 KKK-----PPVSPPLL--LVQDSETTGRQIEDRVALLLSEEVELSSTPPLPASRILKEGW 513 +++ PP L Q+ E R E + +L L PAS E Sbjct: 1242 RRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTL------------PASAPGPEEA 1289 Query: 514 ERAGQCPPPPERKQSFLWEGSALTGAWAMEDFYTARLVPPLVPQRPAQGLMQEPVPPLVP 573 P P R + + S A E++ TA +R +G + P P L+ Sbjct: 1290 LTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSER--RGDKEAPPPVLLT 1347 Query: 574 PEHSELSERRSPALHGTPTAGCGSRGPSPSASQREHQALQDLVDLAREGLSA-------- 625 P+ GTP G G P SA R + Q DL++ S+ Sbjct: 1348 PKAV-----------GTPGGGGGGAVPGISAMSRGDLS-QRAKDLSKRSFSSQRPGMERQ 1395 Query: 626 SPWPGSGGLAGSEGTA--GLDVVPGG 649 + PG GG AGS G++ G PGG Sbjct: 1396 NRRPGPGGKAGSSGSSSGGGGGGPGG 1421 >gi|115430108 rho-related BTB domain containing 3 [Homo sapiens] Length = 611 Score = 49.7 bits (117), Expect = 3e-05 Identities = 42/127 (33%), Positives = 62/127 (48%), Gaps = 10/127 (7%) Query: 685 VNNPHLSDVQFQTDSGEVLYAHKFVLYARCPLLIQYVNNEGFSAVEDGVLTQRVLLGDVS 744 +N P L+DV F+ G + AH+ +L ARC ++ N A VL + + VS Sbjct: 414 LNKPMLADVVFEIQ-GTTVPAHRAILVARCEVMAAMFNGNYMEA--KSVL---IPVYGVS 467 Query: 745 TEAARTFLHYLYTADTGLPPGLSSELSSL--AHRFGVSELVHLCEQVPIATDSEGKPWEE 802 E +FL YLYT D+ P G+ + L A + VS L H+CE + I T + P E Sbjct: 468 KETFLSFLEYLYT-DSCCPAGIFQAMCLLICAEMYQVSRLQHICE-LFIITQLQSMPSRE 525 Query: 803 KEAENCE 809 + N + Sbjct: 526 LASMNLD 532 >gi|150418009 transforming, acidic coiled-coil containing protein 2 isoform a [Homo sapiens] Length = 2948 Score = 49.3 bits (116), Expect = 3e-05 Identities = 84/373 (22%), Positives = 138/373 (36%), Gaps = 51/373 (13%) Query: 1350 GHPHSSPLAPHPISGDRAHFSRRFLKHSPPGPSFLNQ-------TPAGEVVEVGDSDDEQ 1402 G+P + LAP S + S + P P L + T V E DE+ Sbjct: 2101 GNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEE 2160 Query: 1403 EV-------ASHQANRSPPLDSDPPIPIDDCCWH--MEPLSPIPIDHWNLERTGPLSTSS 1453 + AS S + P +++ + P + P+D + E P S Sbjct: 2161 SLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP-PASG 2219 Query: 1454 PSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDV 1513 R N R L T P G T ++ S A L + R F S Sbjct: 2220 GGRVQNSPPVGRKTLP---LTTAPEAGEVTPSDSGGQEDSPAKGL-SVRLEFDYSEDKSS 2275 Query: 1514 WDGEEQRPPET-----PPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSI 1568 WD +++ PP T P A+MP ++P+ +TP+ + PP+ P P Sbjct: 2276 WDNQQENPPPTKKIGKKPVAKMP----LRRPKMKKTPEKLDNTPASPPRSPAEP------ 2325 Query: 1569 METPVLKK----ELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPLLQAP 1624 + P+ K ++D++ K++E + Q+ + D + +S P + Sbjct: 2326 NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS- 2384 Query: 1625 HCQTLASQTYKPSRAGVHA---QQEATTGPGAHRP----KGPAKTKGPRHQR--KHHESI 1675 +T +S + P+ + A + G G ++P K P KT R ++ K Sbjct: 2385 -SKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLS 2443 Query: 1676 TPPSRSPTKEAPP 1688 PPS+ PT A P Sbjct: 2444 DPPSQDPTPAATP 2456 Score = 35.8 bits (81), Expect = 0.39 Identities = 99/496 (19%), Positives = 163/496 (32%), Gaps = 102/496 (20%) Query: 1264 SRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNREGNEVAQKFSVIRPQTPPPQTPSS 1323 S+ ++ + + R G+A VT P A+ E + V +K S ++P P PQ P+ Sbjct: 225 SQEKEAAGGFPPAESRQGVASVQVTPEAPAAAQQGTESSAVLEK-SPLKPMAPIPQDPA- 282 Query: 1324 CLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISGDRAHFSRRFLKHSPPGPSF 1383 P SD R +P P ++ D L S G + Sbjct: 283 ------PRASDRERGQGEAP---------------PQYLTDDLEFLRACHLPRSNSGAA- 320 Query: 1384 LNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDHWNL 1443 P EV +Q V ++ + P W L Sbjct: 321 ----PEAEVNAASQESCQQPVGAYLPHAELP--------------------------WGL 350 Query: 1444 ERTGPLSTSSPSRRMNEAADSRDCRS---PGLLDTTPIRGSCTTQRKLQEKSSGAGSLGN 1500 + + S + EA D+ D + G+ T P + C E G + Sbjct: 351 PSPALVPEAGGSGK--EALDTIDVQGHPQTGMRGTKPNQVVCVAAGGQPE----GGLPVS 404 Query: 1501 SRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPI 1560 PS L E P + + S AQ P +E P ++R+ +P+ Sbjct: 405 PEPSLLTPT------------EEAHPASSLASFPAAQIPIAVEEPGSSSRESVSKAGMPV 452 Query: 1561 TPMPQYSIMETPV--LKKELDRFGVR-PLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSS 1617 + +++ + L++++ G + P+ Q + L+++ E Q Sbjct: 453 SADAAKEVVDAGLVGLERQVSDLGSKGEHPEGDPGEVPAPSPQERGEHLNTEQSHEVQPG 512 Query: 1618 QPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITP 1677 P P Q+ Q P A E+ GP GP K HE T Sbjct: 513 VPPPPLPKEQSHEVQPGAPPPPLPKAPSESARGP-----------PGPTDGAKVHEDSTS 561 Query: 1678 PSRSPTKEAPPGLNDDAQIPASQESVATSVDGSD-SSLSSQSSSSCEFGAAFESAGEEE- 1735 P+ + PG P +E DG D +L + S AF S + E Sbjct: 562 PAVAKEGSRSPG-----DSPGGKEEAPEPPDGGDPGNLQGEDSQ------AFSSKRDPEV 610 Query: 1736 GEGEVSASQAAVQAAD 1751 G+ E+S + ++ D Sbjct: 611 GKDELSKPSSDAESRD 626 Score = 32.0 bits (71), Expect = 5.7 Identities = 35/129 (27%), Positives = 40/129 (31%), Gaps = 18/129 (13%) Query: 1300 EGNEVAQKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAP 1359 EG S RPQ Q P G + SP P P LAP Sbjct: 1759 EGTAALHGDSPARPQQAKEQPGPERPIPAGDG-----KVCVSSPPEPDETHDPKLQHLAP 1813 Query: 1360 HPISGDRAHFSRRFLKHSP-PGPSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSD 1418 + DR SP PGPS L P + V D E + S P+ D Sbjct: 1814 EELHTDR---------ESPRPGPSMLPSVPKKDAPRVMDKVTSDETRGAEGTESSPVADD 1864 Query: 1419 ---PPIPID 1424 P P D Sbjct: 1865 IIQPAAPAD 1873 Score = 31.2 bits (69), Expect = 9.7 Identities = 30/119 (25%), Positives = 48/119 (40%), Gaps = 18/119 (15%) Query: 99 KTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVN--GEGGVLASAP-----DP- 150 +T + Q P +PP SQ + K+Q A S+ G GG ++ DP Sbjct: 12 RTLSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDASSIGSVGLGGFCTASESSASLDPC 71 Query: 151 ---PVLRETAQNTQTGNQQE------PSPNLSREKTRENVPNSDSQPPPSCLTTAVPSP 200 P + E ++ Q E P P+ RE ++P ++ PP CL + +P Sbjct: 72 LVSPEVTEPRKDPQGARGPEGSLLPSPPPSQEREHPSSSMPFAEC-PPEGCLASPAAAP 129 >gi|45827755 transforming, acidic coiled-coil containing protein 2 isoform b [Homo sapiens] Length = 1094 Score = 49.3 bits (116), Expect = 3e-05 Identities = 84/373 (22%), Positives = 138/373 (36%), Gaps = 51/373 (13%) Query: 1350 GHPHSSPLAPHPISGDRAHFSRRFLKHSPPGPSFLNQ-------TPAGEVVEVGDSDDEQ 1402 G+P + LAP S + S + P P L + T V E DE+ Sbjct: 247 GNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEE 306 Query: 1403 EV-------ASHQANRSPPLDSDPPIPIDDCCWH--MEPLSPIPIDHWNLERTGPLSTSS 1453 + AS S + P +++ + P + P+D + E P S Sbjct: 307 SLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP-PASG 365 Query: 1454 PSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDV 1513 R N R L T P G T ++ S A L + R F S Sbjct: 366 GGRVQNSPPVGRKTLP---LTTAPEAGEVTPSDSGGQEDSPAKGL-SVRLEFDYSEDKSS 421 Query: 1514 WDGEEQRPPET-----PPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSI 1568 WD +++ PP T P A+MP ++P+ +TP+ + PP+ P P Sbjct: 422 WDNQQENPPPTKKIGKKPVAKMP----LRRPKMKKTPEKLDNTPASPPRSPAEP------ 471 Query: 1569 METPVLKK----ELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPLLQAP 1624 + P+ K ++D++ K++E + Q+ + D + +S P + Sbjct: 472 NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS- 530 Query: 1625 HCQTLASQTYKPSRAGVHA---QQEATTGPGAHRP----KGPAKTKGPRHQR--KHHESI 1675 +T +S + P+ + A + G G ++P K P KT R ++ K Sbjct: 531 -SKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLS 589 Query: 1676 TPPSRSPTKEAPP 1688 PPS+ PT A P Sbjct: 590 DPPSQDPTPAATP 602 >gi|45827753 transforming, acidic coiled-coil containing protein 2 isoform c [Homo sapiens] Length = 996 Score = 49.3 bits (116), Expect = 3e-05 Identities = 84/373 (22%), Positives = 138/373 (36%), Gaps = 51/373 (13%) Query: 1350 GHPHSSPLAPHPISGDRAHFSRRFLKHSPPGPSFLNQ-------TPAGEVVEVGDSDDEQ 1402 G+P + LAP S + S + P P L + T V E DE+ Sbjct: 179 GNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEE 238 Query: 1403 EV-------ASHQANRSPPLDSDPPIPIDDCCWH--MEPLSPIPIDHWNLERTGPLSTSS 1453 + AS S + P +++ + P + P+D + E P S Sbjct: 239 SLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP-PASG 297 Query: 1454 PSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDV 1513 R N R L T P G T ++ S A L + R F S Sbjct: 298 GGRVQNSPPVGRKTLP---LTTAPEAGEVTPSDSGGQEDSPAKGL-SVRLEFDYSEDKSS 353 Query: 1514 WDGEEQRPPET-----PPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSI 1568 WD +++ PP T P A+MP ++P+ +TP+ + PP+ P P Sbjct: 354 WDNQQENPPPTKKIGKKPVAKMP----LRRPKMKKTPEKLDNTPASPPRSPAEP------ 403 Query: 1569 METPVLKK----ELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPLLQAP 1624 + P+ K ++D++ K++E + Q+ + D + +S P + Sbjct: 404 NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS- 462 Query: 1625 HCQTLASQTYKPSRAGVHA---QQEATTGPGAHRP----KGPAKTKGPRHQR--KHHESI 1675 +T +S + P+ + A + G G ++P K P KT R ++ K Sbjct: 463 -SKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLS 521 Query: 1676 TPPSRSPTKEAPP 1688 PPS+ PT A P Sbjct: 522 DPPSQDPTPAATP 534 >gi|11119414 transforming, acidic coiled-coil containing protein 2 isoform d [Homo sapiens] Length = 1026 Score = 49.3 bits (116), Expect = 3e-05 Identities = 84/373 (22%), Positives = 138/373 (36%), Gaps = 51/373 (13%) Query: 1350 GHPHSSPLAPHPISGDRAHFSRRFLKHSPPGPSFLNQ-------TPAGEVVEVGDSDDEQ 1402 G+P + LAP S + S + P P L + T V E DE+ Sbjct: 179 GNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETPPVKETQQEPDEE 238 Query: 1403 EV-------ASHQANRSPPLDSDPPIPIDDCCWH--MEPLSPIPIDHWNLERTGPLSTSS 1453 + AS S + P +++ + P + P+D + E P S Sbjct: 239 SLVPSGENLASETKTESAKTEGPSPALLEETPLEPAVGPKAACPLDSESAEGVVP-PASG 297 Query: 1454 PSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDV 1513 R N R L T P G T ++ S A L + R F S Sbjct: 298 GGRVQNSPPVGRKTLP---LTTAPEAGEVTPSDSGGQEDSPAKGL-SVRLEFDYSEDKSS 353 Query: 1514 WDGEEQRPPET-----PPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSI 1568 WD +++ PP T P A+MP ++P+ +TP+ + PP+ P P Sbjct: 354 WDNQQENPPPTKKIGKKPVAKMP----LRRPKMKKTPEKLDNTPASPPRSPAEP------ 403 Query: 1569 METPVLKK----ELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDESQSSQPLLQAP 1624 + P+ K ++D++ K++E + Q+ + D + +S P + Sbjct: 404 NDIPIAKGTYTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSYNFDPDTCDESVDPFKTS- 462 Query: 1625 HCQTLASQTYKPSRAGVHA---QQEATTGPGAHRP----KGPAKTKGPRHQR--KHHESI 1675 +T +S + P+ + A + G G ++P K P KT R ++ K Sbjct: 463 -SKTPSSPSKSPASFEIPASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVKKSPKRSPLS 521 Query: 1676 TPPSRSPTKEAPP 1688 PPS+ PT A P Sbjct: 522 DPPSQDPTPAATP 534 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 48.9 bits (115), Expect = 4e-05 Identities = 78/408 (19%), Positives = 142/408 (34%), Gaps = 57/408 (13%) Query: 826 EEEEAETLLKSKDHEEDQ--ENVNEAEMEEIYEFAATQRKLLQEERAAGAGEDADWLEGG 883 E+ E ET++ + EE Q E V E E +E E + + +EE A G E+ Sbjct: 448 EKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETK----- 502 Query: 884 SPVSGQLLAGVQVQKQWDKVEEMEPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEA 943 SP + + + E E P ++EA + E A+ E Sbjct: 503 SPPAEEAAS-----------PEKEAKSPVKEEAKSPAE----------------AKSPEK 535 Query: 944 PEQEAPEEALGHSSCSSPSRDCQAERKEGSLPHSDDA------GDYEQLFSSTQGEISEP 997 E ++P E SP+++ E P ++A E+ S + E P Sbjct: 536 EEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 595 Query: 998 SQITSEPEEQSGAVRERGLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGSSLS 1057 ++ S PE+ V+E + +P + P + P + SP S Sbjct: 596 AEAKS-PEKAKSPVKEEAKSPAEAKSPVKEEAKSPAE-VKSPEKAKSPTKEEAKSPEKAK 653 Query: 1058 TPRSRGGTSQVGSPTLLSPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKGVLMF 1117 +P S + + + S +K + +K P K + + K Sbjct: 654 SPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA-KSPEKAKSPV 712 Query: 1118 PEKSPSIDLTQSNPDHSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLE 1177 E++ S + +S + +K+ S + EE + S E+ + K + E Sbjct: 713 KEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKE 772 Query: 1178 EKKALEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPEN 1225 E ++ D E ++SP + E ++ + L E+ Sbjct: 773 EARS--------------PADKFPEKAKSPVKEEVKSPEKAKSPLKED 806 Score = 48.9 bits (115), Expect = 4e-05 Identities = 93/490 (18%), Positives = 181/490 (36%), Gaps = 45/490 (9%) Query: 787 EQVPIATDSEGKPWEEKEAENCESRAENFQELLRSMWADEEEEAETLLKSKDHEEDQENV 846 E+ A + EGK E E E E E + A E+EA++ +K E+ ++ Sbjct: 473 EEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVK-----EEAKSP 527 Query: 847 NEAEMEEIYEFAATQRKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQWDKVEEM 906 EA+ E E A + ++ E+A ++ E SP + + + + Sbjct: 528 AEAKSPE-KEEAKSPAEVKSPEKAKSPAKE----EAKSPPEAKSPEKEEAKSPAEVKSPE 582 Query: 907 EPLEPGRDEAATTWE-KMGQCALPPPQGQHSGARGAEAP---EQEAPEEALGHSSCSSPS 962 + P ++EA + E K + A P + + A++P E ++P E SP+ Sbjct: 583 KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPT 642 Query: 963 RDCQAERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITS-------EPEEQSGAVRERG 1015 ++ ++ P ++A E+ S + E P + S PE+ V+E Sbjct: 643 KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEA 702 Query: 1016 LEVSHRLAP--WQASPPHPCRFLL-----GPPQGGSPRGSHHTSGSSLSTPRSRGGTSQV 1068 +P +A P + + P + SP S +P + T V Sbjct: 703 KSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSP-EKAKTLDV 761 Query: 1069 GSPTLLSPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKGVLMFPEKSPSIDLTQ 1128 SP +PA + +K P ++ K + K L K+P ++ + Sbjct: 762 KSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE-----KAKSPLKEDAKAPEKEIPK 816 Query: 1129 SNPDHSSSRSQ--------KSSSKLNEEDEVILLLDSDE--ELELEQTKMKSISSDPLEE 1178 S + + K K EE++ ++E + + E+ K +EE Sbjct: 817 KEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEE 876 Query: 1179 KKALEI-SPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRGAPWL 1237 KK + P+ ++ + + D++ +P + + E A P+ + + ++ Sbjct: 877 KKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDA 936 Query: 1238 FCDRESSPSE 1247 S P+E Sbjct: 937 KAKEPSKPAE 946 Score = 32.7 bits (73), Expect = 3.3 Identities = 34/168 (20%), Positives = 64/168 (38%), Gaps = 12/168 (7%) Query: 1607 DSDSEDESQSSQPLLQAPHCQTLAS---QTYKPSRAGVHAQQEATTGPGAHRPKGPAKTK 1663 + E+E++ + ++P + AS + P + + EA + P K PA+ K Sbjct: 487 EGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKS-PEKEEAKSPAEVK 545 Query: 1664 GPRHQR---KHHESITPPSRSPTKE-----APPGLNDDAQIPASQESVATSVDGSDSSLS 1715 P + K P ++SP KE A + A+ PA +E+ + + S Sbjct: 546 SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAK 605 Query: 1716 SQSSSSCEFGAAFESAGEEEGEGEVSASQAAVQAADTDEALRCYIRSK 1763 S + A +S +EE + + T E + ++K Sbjct: 606 SPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAK 653 >gi|40807477 retinoic acid induced 1 [Homo sapiens] Length = 1906 Score = 48.9 bits (115), Expect = 4e-05 Identities = 139/606 (22%), Positives = 204/606 (33%), Gaps = 96/606 (15%) Query: 1190 ELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGR-----RGAPWLFCDRESS 1244 E + + + P + +QE+ G + E G L + + WL E S Sbjct: 786 EASACLGFQEEDPPGEKVASLPGDFKQEEVGGVKEEAGGLLQCPEVAKADRWL----EDS 841 Query: 1245 PSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNREGNEV 1304 ST D L P P SR D ++ + SSL L +P G ++ Sbjct: 842 RHCCSTADFGDL-PLLPPTSRKEDLEAEEEYSSLCELLG-------SPEQRPGMQDPLS- 892 Query: 1305 AQKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISG 1364 P+ P C D + G SP H G S + P G Sbjct: 893 -------------PKAPLICTKEEVEEVLDSKA-GWGSPC--HLSGE---SVILLGPTVG 933 Query: 1365 DRAHFSRRF---LKHSPPGPSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPI 1421 + F L H PG + P GE GDS + + N+ P + PI Sbjct: 934 TESKVQSWFESSLSHMKPG----EEGPDGERAP-GDSTTSDASLAQKPNK--PAVPEAPI 986 Query: 1422 PIDDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGS 1481 + P+P R L + R + EA DS CR+P L + S Sbjct: 987 AKKE---------PVP-------RGKSLRSRRVHRGLPEAEDS-PCRAPVLPKDLLLPES 1029 Query: 1482 CTTQRKLQEKSSGAGSLGNSR--PSFLNSALWDVWDGEEQRPPE-TPPPAQMPSAGGAQ- 1537 CT + Q + +GA G S P +L + + PP T PA GG Q Sbjct: 1030 CTGPPQGQMEGAGAPGRGASEGLPRMCTRSLTALSEPRTPGPPGLTTTPAPPDKLGGKQR 1089 Query: 1538 ------KPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVLKKELDRFGVRPLPKRQM 1591 K G +PK A+ N P +P+ +T KE D +R M Sbjct: 1090 AAFKSGKRVGKPSPKAASSPSN-PAALPVASDSSPMGSKT----KETDSPSTPGKDQRSM 1144 Query: 1592 VL----KLKEIFQYTHQTLDSDSEDESQSSQPLLQAPHCQTLASQTYKPSRAGVHAQQEA 1647 +L K +EIF + ++++ LL H + P + G +Q+ Sbjct: 1145 ILRSRTKTQEIFHSKRRRPSEGRLPNCRATKKLLDNSHLPATFKVSSSPQKEGRVSQRAR 1204 Query: 1648 TTGPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSV 1707 PGA G + P H K + P PTK+ L S S S Sbjct: 1205 VPKPGA----GSKLSDRPLHALKRKSAFMAP--VPTKKRNLVLRS-----RSSSSSNASG 1253 Query: 1708 DGSDSSLSSQSSSSCEFG--AAFESAGEEEGEGEVSASQAAVQAADTDEALRCYIRSKPA 1765 +G D S F ++ + A +G GE + + D L + A Sbjct: 1254 NGGDGKEERPEGSPTLFKRMSSPKKAKPTKGNGEPATKLPPPETPDACLKLASRAAFQGA 1313 Query: 1766 LYQKVL 1771 + KVL Sbjct: 1314 MKTKVL 1319 Score = 34.7 bits (78), Expect = 0.88 Identities = 56/224 (25%), Positives = 87/224 (38%), Gaps = 34/224 (15%) Query: 25 GIDPRSSEDQPESLKTGQMMDESDEDFKELCASFFQRVKKHGI---KEVSGER--KTQKA 79 G P E+ ++ TGQ + S D LC + R K + K++S KT+ Sbjct: 1372 GGSPVGVEEGLVNVGTGQKLPTSGAD--PLCRNPTNRSLKGKLMNSKKLSSTDCFKTEAF 1429 Query: 80 AS------NGTQIRSKLKRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEP 133 S GT + K + K A +GP EK+P G T + R + Q + Sbjct: 1430 TSPEALQPGGTALAPKKRSRKGRAGAHGLSKGPLEKRPYLGPALLLTPRDRASGTQGASE 1489 Query: 134 AHSVNG-------EGGVLASAPD-PPVLRETAQNTQTGNQQEPSPNLSREKTRENVPNSD 185 +S G E G+ + P+ P +T Q G+ S + + TR N+ Sbjct: 1490 DNSGGGGKKPKMEELGLASQPPEGRPCQPQTRAQKQPGHTNYSSYSKRKRLTRGRAKNTT 1549 Query: 186 SQPPPSCLTTAVPSPSKPRTAQLVLQRMQQFKRADPE-RLRHAS 228 S SP K R + Q++ A+PE RL++ S Sbjct: 1550 S------------SPCKGRAKRRRQQQVLPLDPAEPEIRLKYIS 1581 Score = 34.3 bits (77), Expect = 1.1 Identities = 95/442 (21%), Positives = 151/442 (34%), Gaps = 80/442 (18%) Query: 940 GAEAPEQEAPEEALGHSSCSSPSRDCQAERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQ 999 G E+ Q E +L H D ER G SD + + + + E Sbjct: 933 GTESKVQSWFESSLSHMKPGEEGPD--GERAPGDSTTSDASLAQKP----NKPAVPEAPI 986 Query: 1000 ITSEPEEQSGAVRERGLEVSHRLAPWQASPPHPCR-------FLL-----GPPQGGSPRG 1047 EP + ++R R + HR P + PCR LL GPPQG Sbjct: 987 AKKEPVPRGKSLRSRRV---HRGLP--EAEDSPCRAPVLPKDLLLPESCTGPPQGQMEGA 1041 Query: 1048 SHHTSGSSLSTPR--SRGGTSQVGSPTLLSPAVPSKQKRDRSILTLSKEPGHQKGKERRS 1105 G+S PR +R T+ L P P + T P GK+R + Sbjct: 1042 GAPGRGASEGLPRMCTRSLTA------LSEPRTPGPP----GLTTTPAPPDKLGGKQRAA 1091 Query: 1106 VLECRNKG-----VLMFPEKSPSIDL-TQSNPDHSSSRSQKSSSKLNEEDEVILLLDSDE 1159 + G P ++ + + S+P S ++ S S ++ ++L + Sbjct: 1092 FKSGKRVGKPSPKAASSPSNPAALPVASDSSPMGSKTKETDSPSTPGKDQRSMILRSRTK 1151 Query: 1160 ELELEQTKMKSISSDPLEEKKALEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDE 1219 E+ +K + S L +A + +L + A + S SP + V Q Sbjct: 1152 TQEIFHSKRRRPSEGRLPNCRATK------KLLDNSHLPATFKVSSSPQKEGRVSQ---- 1201 Query: 1220 GALPENRGSLGRRGAPWLFCDRESSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLR 1279 R + + GA DR P A ++++ P P R+ S++ SS Sbjct: 1202 ------RARVPKPGAGSKLSDR---PLHALKRKSAFMAPV-PTKKRNLVLRSRSSSSSNA 1251 Query: 1280 SGLAVQAVTQH------------TPRASVGNREGNEVAQKFSVIRPQTPPPQTPSSCLTP 1327 SG + +P+ + + E A K PPP+TP +CL Sbjct: 1252 SGNGGDGKEERPEGSPTLFKRMSSPKKAKPTKGNGEPATKL-------PPPETPDACLKL 1304 Query: 1328 VSPGTSDGRRQGHRSPSRPHPG 1349 S G + P R G Sbjct: 1305 ASRAAFQGAMKTKVLPPRKGRG 1326 >gi|19924099 synapsin I isoform Ia [Homo sapiens] Length = 705 Score = 47.8 bits (112), Expect = 1e-04 Identities = 65/260 (25%), Positives = 79/260 (30%), Gaps = 49/260 (18%) Query: 1314 QTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISGDRAHFSRRF 1373 Q PPPQ P PG +RQG RP P G H S L P S Sbjct: 459 QRPPPQGG-----PPQPGPGP-QRQGPPLQQRPPPQGQQHLSGLGPPAGSP--------- 503 Query: 1374 LKHSPPGPSFLNQTPAGEVVEVGDSDDEQE-----------VASHQANRSPPLDSDPPIP 1422 L P P+ Q PA + Q A A+ SP + PP Sbjct: 504 LPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPP-- 561 Query: 1423 IDDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSC 1482 P P G P + A +R G P G Sbjct: 562 --QATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAG---PVPRTGPP 616 Query: 1483 TTQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGL 1542 TTQ Q + SG G G +P Q+P + PP +AGG P+ L Sbjct: 617 TTQ---QPRPSGPGPAGRPKPQL------------AQKPSQDVPPPATAAAGGPPHPQ-L 660 Query: 1543 ETPKGANRKKNLPPKVPITP 1562 + NLP P P Sbjct: 661 NKSQSLTNAFNLPEPAPPRP 680 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/63 (31%), Positives = 28/63 (44%) Query: 1650 GPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDG 1709 GPG R P + + P ++H + PP+ SP + P Q PASQ + T G Sbjct: 471 GPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQG 530 Query: 1710 SDS 1712 S Sbjct: 531 RQS 533 Score = 36.6 bits (83), Expect = 0.23 Identities = 44/191 (23%), Positives = 68/191 (35%), Gaps = 17/191 (8%) Query: 1371 RRFLKHSPPGPSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIPIDDCCWHM 1430 R+ + + PG QTP+ + +G +Q A A + PP PP P Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQP-AGPPAQQRPPPQGGPPQPGPGPQRQG 478 Query: 1431 EPLS--PIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKL 1488 PL P P +L GP + S +R+ + + P P +G R + Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAP--QQPASQAAPPTQGQGRQSRPV 536 Query: 1489 QEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGA 1548 + G G+ +RP S QR P + S G P+ P G Sbjct: 537 ---AGGPGAPPAARPPASPSP---------QRQAGPPQATRQTSVSGPAPPKASGAPPGG 584 Query: 1549 NRKKNLPPKVP 1559 +++ P K P Sbjct: 585 QQRQGPPQKPP 595 Score = 32.3 bits (72), Expect = 4.4 Identities = 30/113 (26%), Positives = 39/113 (34%), Gaps = 10/113 (8%) Query: 97 ATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP-PVLRE 155 AT+ ++ GPA PP S AP +QR P G G A PV R Sbjct: 563 ATRQTSVSGPA---PPKASGAPPGGQQR------QGPPQKPPGPAGPTRQASQAGPVPRT 613 Query: 156 TAQNTQTGNQQEPSPNLSREKTRENVPNSDSQPPPSCLTTAVPSPSKPRTAQL 208 TQ P P + P+ D PP + P P ++ L Sbjct: 614 GPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSL 666 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 47.8 bits (112), Expect = 1e-04 Identities = 105/519 (20%), Positives = 181/519 (34%), Gaps = 53/519 (10%) Query: 1246 SEASTTDTSWLVPATPLASRSRDCSSQT--QISSLRSGLAVQAVTQHTPRASVGNREGNE 1303 SEAST T+ + TP+ + + SS T + +S+ + + T T + Sbjct: 644 SEASTLSTTPVDSNTPVTTSTEATSSSTTAEGTSMPTSTYTEGSTPLTSMPVNTTLVASS 703 Query: 1304 VAQKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPIS 1363 A S T P T S+ + SP T+DG +PS S+PL P+S Sbjct: 704 EASTLSTTPVDTSTPVTTSTEASS-SPTTADGASMPTSTPSE-------GSTPLTSMPVS 755 Query: 1364 GDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIPI 1423 S + P + + T + E + + + + PL + P+ I Sbjct: 756 KTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSI 815 Query: 1424 DDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCT 1483 +P+ + T P+ ++SP E + S TP G+ Sbjct: 816 ----------TPVTSPEASTLSTTPVDSNSPVTTSTEVSSS----------PTPAEGTSM 855 Query: 1484 TQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLE 1543 E + S+ S SA+ + TP P + Sbjct: 856 PTSTYSEGRTPLTSMPVSTTLVATSAISTL--------STTPVDTSTPVTNSTEARSSPT 907 Query: 1544 TPKGANRKKNLPPK--VPITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQ- 1600 T +G + + P + P+T MP + TPV+ E P+ V E Sbjct: 908 TSEGTSMPTSTPGEGSTPLTSMPDST---TPVVSSEARTLSATPVDTSTPVTTSTEATSS 964 Query: 1601 -YTHQTLDSDSEDESQSSQPLLQAPHCQTLA--SQTYKPSRAGVHAQQEATTGPGAHRPK 1657 T + + S+ + PL P TL S+ S V + TT A P Sbjct: 965 PTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP 1024 Query: 1658 GPAK-TKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSS 1716 A+ T P E TP +R P ++ + + + +T V + S +S Sbjct: 1025 PTAEGTSMPTSTPS--EGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPV--TTYSQAS 1080 Query: 1717 QSSSSCEFGAAFESAGEEEGEGEVSASQAAVQAADTDEA 1755 SS++ + G + ++ EG +++ + + + EA Sbjct: 1081 SSSTTAD-GTSMPTSTYSEGSTPLTSVPVSTRLVVSSEA 1118 Score = 45.8 bits (107), Expect = 4e-04 Identities = 112/521 (21%), Positives = 167/521 (32%), Gaps = 85/521 (16%) Query: 1243 SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQ------------- 1289 S+PSE S TS V TP+AS S T + S + V+ Sbjct: 1624 STPSEGSPLLTSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTS 1683 Query: 1290 -----HTPRASVGNREGNEVAQKFSVIRPQTPPPQTPSSCLTPV--SPGTSDGRRQGHRS 1342 TP S+ R + S + TP + T SP TS+G + + Sbjct: 1684 TYTEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNST 1743 Query: 1343 PSRPHPGGHPHSS-PLAPHPISGDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDDE 1401 PS G P +S P++ P+ A S L+ TP V Sbjct: 1744 PSE---GTTPLTSIPVSTTPVLSSEA--------------STLSATPIDTSTPV------ 1780 Query: 1402 QEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDHWNL--ERTGPLSTSSPSRRMN 1459 S +A SP IP M PL+ P+ H + LST+ Sbjct: 1781 --TTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSP 1838 Query: 1460 EAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQ 1519 + SP TP G+ E S+ S+ S + +S E Sbjct: 1839 VVTSTAVSSSP-----TPAEGTSIATSTPSEGSTALTSIPVSTTTVASS--------ETN 1885 Query: 1520 RPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLP--PKVPITPMPQYSIMETPVLKKE 1577 TP P AQ T G++ + P + P+T +P + T V E Sbjct: 1886 TLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIP---VSTTTVASSE 1942 Query: 1578 LDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDSEDE---SQSSQPLLQAPHCQTLA---- 1630 ++ R V + + T D S S+ S PL P TL Sbjct: 1943 INTLSTTLADTRTPVTTYSQA-SSSPTTADGTSMPTPAYSEGSTPLTSMPLSTTLVVSSE 2001 Query: 1631 --------SQTYKPSRAGVHAQQEATTGPGAH-RPKGPAKTKGPRHQRKHHESITPPSRS 1681 T P+ TT G + P++ P ++ S Sbjct: 2002 ASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEG 2061 Query: 1682 PTKEAPPGLNDDAQIPASQE-SVATSVDGSDSSLSSQSSSS 1721 T P ++ Q+ S E S + + +GS ++S+ S S Sbjct: 2062 NTLSTTP-VDSKTQVTNSTEASSSATAEGSSMTISAPSEGS 2101 Score = 42.7 bits (99), Expect = 0.003 Identities = 108/507 (21%), Positives = 168/507 (33%), Gaps = 74/507 (14%) Query: 1243 SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNR--- 1299 S+ SE ST T V TP+ S + S T + + + + +P S G Sbjct: 3098 STYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDT-STPVTTSTEAHSSPTTSEGTSMPT 3156 Query: 1300 ----EGNE------VAQKFSVIRPQTPPPQTPSSCLTPVSPGT---SDGRRQGHRSP-SR 1345 EG+ V+ V + TP TPV+ T S +G P S Sbjct: 3157 STPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTST 3216 Query: 1346 PHPGGHPHSS-PLAPHPISGDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDDEQEV 1404 P G P +S P++ P++ A S L+ TP + Sbjct: 3217 PSEGMTPLTSVPVSNTPVASSEA--------------SILSTTPVDSNTPL--------T 3254 Query: 1405 ASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDHWNL--ERTGPLSTSSPSRRMNEAA 1462 S +A+ SPP +P PL+ +P+ + T LST+ Sbjct: 3255 TSTEASSSPPTAEGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTT 3314 Query: 1463 DSRDCRSPGLLDTTPIRGSCTTQRK--LQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQR 1520 S+ SP + D T + S ++ L S + +S S L++ D Sbjct: 3315 YSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDT------- 3367 Query: 1521 PPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVLKKELDR 1580 TP ++ EG P + P TP+ + TPV+ E++ Sbjct: 3368 --STPVTTSTEASLSPTTAEGTSIPTSS-------PSEGTTPLASMPVSTTPVVSSEVNT 3418 Query: 1581 FGVRPLPKRQMVLKLKE------IFQYTHQTLDSDSEDESQ-SSQPLLQAPHCQTLASQT 1633 P+ +V E I + T + SE + S PL P + AS Sbjct: 3419 LSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTL 3478 Query: 1634 YKPSRAGVHAQQEATT-GPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPTKEAPPGLND 1692 S V TT P P T P E TP + P P ++ Sbjct: 3479 ---STTPVDTSTPVTTSSPTNSSPTTAEVTSMPTSTA--GEGSTPLTNMPVSTTPVASSE 3533 Query: 1693 DAQIPASQESVATSVDGSDSSLSSQSS 1719 + + + T V S + SS ++ Sbjct: 3534 ASTLSTTPVDSNTFVTSSSQASSSPAT 3560 Score = 42.4 bits (98), Expect = 0.004 Identities = 109/518 (21%), Positives = 168/518 (32%), Gaps = 78/518 (15%) Query: 1243 SSPSEASTTDTSWLVPATPLASRSRDCSSQTQI--------SSLRSGLAVQAVTQHTPRA 1294 S+PSE ST+ TS LV P+AS S T + S+ S A P + Sbjct: 2626 STPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTS 2685 Query: 1295 SVGNRE-------------GNEVAQKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHR 1341 + G R N A S T P T +S SP T++G Sbjct: 2686 TPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVT-TSAEASSSPTTAEGTSMRIS 2744 Query: 1342 SPSRPHPGGHPHSSPL-APHPISGDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDD 1400 +PS G P +S L + P++ A S ++ T + V Sbjct: 2745 TPS---DGSTPLTSILVSTLPVASSEA--------------STVSTTAVDTSIPV----- 2782 Query: 1401 EQEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNE 1460 S +A+ SP +P PL+ +P++H P+++S Sbjct: 2783 ---TTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNH------TPVASSEAGTLSTT 2833 Query: 1461 AADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQR 1520 D+ S + +T S TT + S A S G++ + + + V E Sbjct: 2834 PVDT----STPVTTSTKASSSPTTAEGIVVPISTA-SEGSTLLTSIPVSTTPVASSEAST 2888 Query: 1521 PPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVLKKELDR 1580 TP +P + T +G + + P +V TP+ + PV E Sbjct: 2889 LSTTPVDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVS-TPLTSILVSTVPVAGSEAST 2947 Query: 1581 FGVRPLPKRQMVLKLKE------IFQYTHQTLDSDSE------DESQSSQPLL--QAPHC 1626 P+ R V E + T + + E S S+ P+ +A Sbjct: 2948 LSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTL 3007 Query: 1627 QTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITP---PSRSPT 1683 + T P A TT G P ++G S TP P S Sbjct: 3008 SRTPADTSTPVTTSTEASSSPTTAEGTGIPIS-TPSEGSTPLTSIPVSTTPVAIPEASTL 3066 Query: 1684 KEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSS 1721 P N S T +G+ +S+ S S Sbjct: 3067 STTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGS 3104 Score = 41.2 bits (95), Expect = 0.009 Identities = 99/519 (19%), Positives = 159/519 (30%), Gaps = 67/519 (12%) Query: 1241 RESSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNRE 1300 R S+PS+ ST TS LV P+AS S T + + S+ Sbjct: 2742 RISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDT-----------------SIPVTT 2784 Query: 1301 GNEVAQKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPH 1360 E + + + P TPS TP++ P P + L+ Sbjct: 2785 STEASSSPTTAEVTSMPTSTPSETSTPLT-----------SMPVNHTPVASSEAGTLSTT 2833 Query: 1361 PISGDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDD-----------EQEVASHQA 1409 P+ + SP T G VV + + + VAS +A Sbjct: 2834 PVDTSTPVTTSTKASSSP-------TTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEA 2886 Query: 1410 NRSPPLDSDPPIPIDDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRS 1469 + D IP+ SP + ++ + P S+P + + Sbjct: 2887 STLSTTPVDTSIPVTTSTEGSS--SPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSE 2944 Query: 1470 PGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRP-----------SFLNSALWDVWDGEE 1518 L TTP+ + SS + G S P + ++ + V E Sbjct: 2945 ASTLSTTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEA 3004 Query: 1519 QRPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVLKKEL 1578 TP P + T +G + P + TP+ + TPV E Sbjct: 3005 STLSRTPADTSTPVTTSTEASSSPTTAEGTGIPISTPSE-GSTPLTSIPVSTTPVAIPEA 3063 Query: 1579 DRFGVRPLPKRQMVLKLKEIFQ--YTHQTLDSDSEDESQSSQPLLQAPHCQT--LASQTY 1634 P+ V+ E+ + S+ S PL P T +S Sbjct: 3064 STLSTTPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS 3123 Query: 1635 KPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRK-HHESITPPSRSPTKEAPPGLNDD 1693 S V TT AH P ++G E TP + P ++D Sbjct: 3124 TLSTTPVDTSTPVTTSTEAH--SSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSED 3181 Query: 1694 AQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAG 1732 + + A+ +T V S + SS ++ + S G Sbjct: 3182 STLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEG 3220 Score = 40.4 bits (93), Expect = 0.016 Identities = 105/479 (21%), Positives = 154/479 (32%), Gaps = 69/479 (14%) Query: 1243 SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGN---- 1298 S+PSE S TS V TP+ S S T + S S + +P + G Sbjct: 799 STPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDS-NSPVTTSTEVSSSPTPAEGTSMPT 857 Query: 1299 ---REGN------EVAQKFSVIRPQTPPPQTPSSCLTPV--------SPGTSDGRRQGHR 1341 EG V+ + TP TPV SP TS+G Sbjct: 858 STYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSM--- 914 Query: 1342 SPSRPHPGGHPHSS-PLAPHP-ISGDRAHFSRRFLKHSPP---------------GPSFL 1384 S P G P +S P + P +S + S + S P G S Sbjct: 915 PTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 974 Query: 1385 NQTPA-GEVVEVGDSDDEQEVASHQAN--RSPPLDSDPPIPIDDCCWHMEPLSPIP-IDH 1440 TP+ G VA+ +A+ + P+DS+ P+ E SP P + Sbjct: 975 TSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTS-----TEASSPPPTAEG 1029 Query: 1441 WNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGN 1500 ++ + P S+P RM + L TTP S Q SS + G Sbjct: 1030 TSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTTADGT 1089 Query: 1501 SRPSFLNS-----------ALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGAN 1549 S P+ S + V E TP +P + T +G + Sbjct: 1090 SMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTS 1149 Query: 1550 RKKNLPPKVPITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQ--YTHQTLD 1607 + PP TP+ + T V+ E + P+ + V E T + Sbjct: 1150 IPTS-PPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTS 1208 Query: 1608 SDSEDESQSSQPLLQAP--HCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKG 1664 + + S PL P H +S+ S + V TT A P +G Sbjct: 1209 MPTSTPGERSTPLTSMPVRHTPVASSEASTLSTSPVDTSTPVTT--SAETSSSPTTAEG 1265 Score = 38.1 bits (87), Expect = 0.079 Identities = 112/519 (21%), Positives = 159/519 (30%), Gaps = 91/519 (17%) Query: 1243 SSPSEASTTDTSWLVPATPLASRSR--------DCSSQTQISSLRSGLAVQAVTQHTPRA 1294 S+PSE S + T V PL S D S+ S+ S + P++ Sbjct: 150 STPSEESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKS 209 Query: 1295 SVGNREGNEVAQKFSVIRPQTPPPQ------TPSSCLTPV--------SPGTSDGRRQGH 1340 + N EG+ + + TP TPV SP T++G + Sbjct: 210 T--NSEGSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAEGPSLSN 267 Query: 1341 RSPSRPHPGGHPHSSPLAPHPISGDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDD 1400 +PS GG S+PL P+S S S L+ TPA + V Sbjct: 268 SAPS----GG---STPLTRMPLSVMLVVSSEA---------STLSTTPAATNIPV----- 306 Query: 1401 EQEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNE 1460 + S +A+ SP IP PL+ P T P++TS S Sbjct: 307 ---ITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPAS------TMPVATSEMSTLSIT 357 Query: 1461 AADSRDC----RSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDG 1516 D+ P L TT S T S G+ L N S + A Sbjct: 358 PVDTSTLVTTSTEPSSLPTTAEATSMLTSTL----SEGSTPLTNMPVSTILVA------S 407 Query: 1517 EEQRPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVLKK 1576 E T P A + T P TP+ + TPV Sbjct: 408 SEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASS 467 Query: 1577 ELDRFGVRPLPKRQMVLKLKEIFQY--THQTLDSDSEDESQSSQPLL------------Q 1622 E P+ + V E T + + S+ S PL + Sbjct: 468 EASNLSTTPVDSKTQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTSMSVSTMPVASSE 527 Query: 1623 APHCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKG-PAKTKGPRHQRKHHESITPPSRS 1681 A T T P A +TT G P P++ P + S + Sbjct: 528 ASTLSTTPVDTSTPVTTSSEASSSSTTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEA 587 Query: 1682 PTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSS 1720 T P S V TS + S SS +++ +S Sbjct: 588 STTSTTPA--------DSNTFVTTSSEASSSSTTAEGTS 618 Score = 37.7 bits (86), Expect = 0.10 Identities = 108/524 (20%), Positives = 159/524 (30%), Gaps = 90/524 (17%) Query: 1243 SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISS---------------LRSGLAVQAV 1287 S+PSE S TS + TP+AS S T + S G ++Q Sbjct: 2095 SAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTS 2154 Query: 1288 TQHTPRASVGNREGNEVAQKFSVIRPQTPPPQTPSSCLT-----PVSPGTSDGRRQGHRS 1342 T R + + + S I + P S+ +T SP TS+G + Sbjct: 2155 TYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTST 2214 Query: 1343 PSRPHPGGHPHSS-PLAPHPISGDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDDE 1401 PS G P +S P++ P+ A S L+ TP V Sbjct: 2215 PSE---GSTPFTSMPVSTMPVVTSEA--------------STLSATPVDTSTPV------ 2251 Query: 1402 QEVASHQANRSPPLDSDPPIPIDDCCWHMEPLSPIPIDHW---NLE----RTGPLSTSSP 1454 S +A SP IP PL+ IP+ H N E T P+ +++P Sbjct: 2252 --TTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTP 2309 Query: 1455 SRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDVW 1514 EA+ + T+ T ++ ++ S S S Sbjct: 2310 FTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLS---------- 2359 Query: 1515 DGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKVPITPMPQYSIMETPVL 1574 P +T P S G+ +T + P+T +P + PV+ Sbjct: 2360 ----TTPADTSTPVTTYSQAGSSPTTADDTSMPTSTYSE--GSTPLTSVP---VSTMPVV 2410 Query: 1575 KKELDRFGVRPLPKRQMVLKLKEIFQ--YTHQTLDSDSEDESQSSQPLLQAP-------- 1624 E P+ V E T + + S+ + PL P Sbjct: 2411 SSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVS 2470 Query: 1625 ----HCQTLASQTYKPSRAGVHAQQEATTGPGAHRPKGPAKTKGPRHQRKHHESITP--- 1677 T T P A TT P A ++G S TP Sbjct: 2471 SEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPISTA-SEGSTLLTSIPVSTTPVAS 2529 Query: 1678 PSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSS 1721 P S P N S ATS +G+ S+ S S Sbjct: 2530 PEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGS 2573 Score = 37.4 bits (85), Expect = 0.14 Identities = 99/526 (18%), Positives = 176/526 (33%), Gaps = 67/526 (12%) Query: 1246 SEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNREGNEVA 1305 SEAST T+ + +TP+ + + SS T + + TP S+ + + Sbjct: 703 SEASTLSTTPVDTSTPVTTSTEASSSPTTADGASMPTSTPS-EGSTPLTSMPVSKTLLTS 761 Query: 1306 QKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHP--HSSPLAPHPIS 1363 + S + T P T + T S +G P G P S P++ P++ Sbjct: 762 SEASTL--STTPLDTSTHITTSTEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVT 819 Query: 1364 GDRAHFSRRFLKHSPPGPSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIPI 1423 P S L+ TP + S + + SP +P Sbjct: 820 S--------------PEASTLSTTPV--------DSNSPVTTSTEVSSSPTPAEGTSMPT 857 Query: 1424 DDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCT 1483 PL+ +P+ T ++TS+ S D+ S + ++T R S T Sbjct: 858 STYSEGRTPLTSMPVS------TTLVATSAISTLSTTPVDT----STPVTNSTEARSSPT 907 Query: 1484 TQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLE 1543 T +S G G++ + + + V E + TP P + Sbjct: 908 TSEGTSMPTSTPGE-GSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVTTSTEATSSPT 966 Query: 1544 TPKGANRKKNLPPKVPITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQ--Y 1601 T +G + + P + TP+ + T V E P+ + E Sbjct: 967 TAEGTSIPTSTPSE-GTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPPP 1025 Query: 1602 THQTLDSDSEDESQSSQPLLQAPHCQTLA------------SQTYKPSRAGVHAQQEATT 1649 T + + S+ S PL + P T+ + T P A +TT Sbjct: 1026 TAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSSTT 1085 Query: 1650 GPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDG 1709 G P + E TP + P ++ + + S V TS+ Sbjct: 1086 ADGTSMPTS-----------TYSEGSTPLTSVPVSTRLVVSSEASTL--STTPVDTSIPV 1132 Query: 1710 SDSSLSSQSSSSCEFGAAFESAGEEEGEGEVSASQAAVQAADTDEA 1755 + S+ +S S ++ E G + ++ EG +++ + + EA Sbjct: 1133 TTSTEASSSPTTAE-GTSIPTSPPSEGTTPLASMPVSTTLVVSSEA 1177 Score = 34.3 bits (77), Expect = 1.1 Identities = 101/516 (19%), Positives = 158/516 (30%), Gaps = 82/516 (15%) Query: 1243 SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNREGN 1302 S+PSE +T TS V TP+ S S T + + G T +S EG Sbjct: 1389 SNPSEGTTPLTSIPVSTTPVVSSEASTLSATPVDTSTPG-----TTSAEATSSPTTAEGI 1443 Query: 1303 EVAQKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPI 1362 + P TPS TP+ P P + +S L+ P+ Sbjct: 1444 SI------------PTSTPSEGKTPLK-----------SIPVSNTPVANSEASTLSTTPV 1480 Query: 1363 SGDRAHFSRRFLKHSP---PGPSFLNQTPA-GEVVEVGDSDDEQEVASHQANRSPPLDSD 1418 + + + SP G S TP+ G VAS + N + Sbjct: 1481 DSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTPAV 1540 Query: 1419 PPIPIDDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPI 1478 P+ + SP D +++ + S+P + + L TTPI Sbjct: 1541 TSTPV--TTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPI 1598 Query: 1479 RGSCTTQRKLQEKSS---GAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGG 1535 + SS S+ S PS + L + P T P A ++ Sbjct: 1599 DSKTQVTASTEASSSTTAEGSSMTISTPSEGSPLLTSI-------PVSTTPVASPEASTL 1651 Query: 1536 AQKPEGLETPKGANRKKNLPP------KVPI-------TPMPQYSIMETPVLKKELDRFG 1582 + P +P + + + P +P TP+ ++ TPV + Sbjct: 1652 STTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLS 1711 Query: 1583 VRPLPKRQMVLKLKEI--FQYTHQTLDSDSEDESQSSQPLLQAP---------HCQTLAS 1631 P+ V E T + + S+ + PL P TL++ Sbjct: 1712 TTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSA 1771 Query: 1632 ---QTYKPSRAGVHAQQEATTGPGAHRPKG-------PAKTKGPRHQRKHHESITPPSRS 1681 T P A TT G P P + H + + S + Sbjct: 1772 TPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTT 1831 Query: 1682 PTKEAPPGLNDDA----QIPASQESVATSVDGSDSS 1713 P P + A PA S+ATS S+ Sbjct: 1832 PVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSEGST 1867 >gi|164419758 bromodomain containing 2 [Homo sapiens] Length = 801 Score = 47.4 bits (111), Expect = 1e-04 Identities = 87/373 (23%), Positives = 137/373 (36%), Gaps = 57/373 (15%) Query: 907 EPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAE------APEQEAPEEALGHSSCSS 960 EPLEPG +T A+PP + S +E + E+E E+ S Sbjct: 456 EPLEPGPLPVST--------AMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEES 507 Query: 961 PSRDCQAERKEGSLPHSDDA-GDYEQLFSSTQGEISEPSQITSEPEEQS--GAVRERGLE 1017 S D + ER + +EQL + +QG IS+P + + E++ A + RG Sbjct: 508 ESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRA 567 Query: 1018 VSHR--LAPWQASPPHPCRFLLGPPQGG-----SPRGSHHTSGSSLSTPRSRGGTSQVGS 1070 + P PP P + GG P G + GS P+ T+ Sbjct: 568 GADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPAL 627 Query: 1071 PTLL-------SPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKGVLMFPEKSPS 1123 PT S + +KR S L ++K PG + G+ V + + PS Sbjct: 628 PTGYDSEEEEESRPMSYDEKRQLS-LDINKLPGEKLGRV-----------VHIIQAREPS 675 Query: 1124 IDLTQSNPD--HSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLEEKKA 1181 L SNP+ + K S+ E V+ L K + + L +K Sbjct: 676 --LRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTKEELALEKK 733 Query: 1182 LEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRGAPWLFCDR 1241 E+ R + DV ++ PP+ E + + ++ R A D Sbjct: 734 RELEKR------LQDVSGQLNSTKKPPKK----ANEKTESSSAQQVAVSRLSASSSSSDS 783 Query: 1242 ESSPSEASTTDTS 1254 SS S +S++DTS Sbjct: 784 SSSSSSSSSSDTS 796 Score = 35.4 bits (80), Expect = 0.51 Identities = 50/232 (21%), Positives = 84/232 (36%), Gaps = 21/232 (9%) Query: 24 PGIDPRSSEDQPE------SLKTGQMMDESDEDFKELCASFFQRVKKHGIKEVSGE---- 73 PG+ SSE E S + + DE DE+ +E +S + + H + E+ + Sbjct: 471 PGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAV 530 Query: 74 RKTQKAASNGTQIRSKLKRTKQTATKTKTLQ-------GPAEKKPPSGSQAPRTKKQRVT 126 + A S G + K KR K+ K + + + K P + P+ KK + Sbjct: 531 HEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSK-- 588 Query: 127 KWQASEPAHSVNGEGGVLASAPDPPVLRETAQNTQTGNQQEPSPNLSREKTRENVPNSDS 186 K S + G G S L + A T+T P+ S E+ + D Sbjct: 589 KASGSGGGSAALGPSGFGPSGGSGTKLPKKA--TKTAPPALPTGYDSEEEEESRPMSYDE 646 Query: 187 QPPPSCLTTAVPSPSKPRTAQLVLQRMQQFKRADPERLRHASEECSLEAARE 238 + S +P R ++ R + ++PE + E RE Sbjct: 647 KRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRE 698 Score = 33.5 bits (75), Expect = 2.0 Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 12/103 (11%) Query: 1666 RHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFG 1725 R+ + E + P + PPGL + +S+ES SS+SSS E Sbjct: 449 RYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEES------------SSESSSEEEEE 496 Query: 1726 AAFESAGEEEGEGEVSASQAAVQAADTDEALRCYIRSKPALYQ 1768 E EEE E S + A + A+ E LR AL Q Sbjct: 497 EDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQ 539 >gi|4826806 bromodomain containing 2 [Homo sapiens] Length = 801 Score = 47.4 bits (111), Expect = 1e-04 Identities = 87/373 (23%), Positives = 137/373 (36%), Gaps = 57/373 (15%) Query: 907 EPLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAE------APEQEAPEEALGHSSCSS 960 EPLEPG +T A+PP + S +E + E+E E+ S Sbjct: 456 EPLEPGPLPVST--------AMPPGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEES 507 Query: 961 PSRDCQAERKEGSLPHSDDA-GDYEQLFSSTQGEISEPSQITSEPEEQS--GAVRERGLE 1017 S D + ER + +EQL + +QG IS+P + + E++ A + RG Sbjct: 508 ESSDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRA 567 Query: 1018 VSHR--LAPWQASPPHPCRFLLGPPQGG-----SPRGSHHTSGSSLSTPRSRGGTSQVGS 1070 + P PP P + GG P G + GS P+ T+ Sbjct: 568 GADEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPKKATKTAPPAL 627 Query: 1071 PTLL-------SPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKGVLMFPEKSPS 1123 PT S + +KR S L ++K PG + G+ V + + PS Sbjct: 628 PTGYDSEEEEESRPMSYDEKRQLS-LDINKLPGEKLGRV-----------VHIIQAREPS 675 Query: 1124 IDLTQSNPD--HSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLEEKKA 1181 L SNP+ + K S+ E V+ L K + + L +K Sbjct: 676 --LRDSNPEEIEIDFETLKPSTLRELERYVLSCLRKKPRKPYTIKKPVGKTKEELALEKK 733 Query: 1182 LEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRGAPWLFCDR 1241 E+ R + DV ++ PP+ E + + ++ R A D Sbjct: 734 RELEKR------LQDVSGQLNSTKKPPKK----ANEKTESSSAQQVAVSRLSASSSSSDS 783 Query: 1242 ESSPSEASTTDTS 1254 SS S +S++DTS Sbjct: 784 SSSSSSSSSSDTS 796 Score = 35.4 bits (80), Expect = 0.51 Identities = 50/232 (21%), Positives = 84/232 (36%), Gaps = 21/232 (9%) Query: 24 PGIDPRSSEDQPE------SLKTGQMMDESDEDFKELCASFFQRVKKHGIKEVSGE---- 73 PG+ SSE E S + + DE DE+ +E +S + + H + E+ + Sbjct: 471 PGLAKSSSESSSEESSSESSSEEEEEEDEEDEEEEESESSDSEEERAHRLAELQEQLRAV 530 Query: 74 RKTQKAASNGTQIRSKLKRTKQTATKTKTLQ-------GPAEKKPPSGSQAPRTKKQRVT 126 + A S G + K KR K+ K + + + K P + P+ KK + Sbjct: 531 HEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGADEDDKGPRAPRPPQPKKSK-- 588 Query: 127 KWQASEPAHSVNGEGGVLASAPDPPVLRETAQNTQTGNQQEPSPNLSREKTRENVPNSDS 186 K S + G G S L + A T+T P+ S E+ + D Sbjct: 589 KASGSGGGSAALGPSGFGPSGGSGTKLPKKA--TKTAPPALPTGYDSEEEEESRPMSYDE 646 Query: 187 QPPPSCLTTAVPSPSKPRTAQLVLQRMQQFKRADPERLRHASEECSLEAARE 238 + S +P R ++ R + ++PE + E RE Sbjct: 647 KRQLSLDINKLPGEKLGRVVHIIQAREPSLRDSNPEEIEIDFETLKPSTLRE 698 Score = 33.5 bits (75), Expect = 2.0 Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 12/103 (11%) Query: 1666 RHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFG 1725 R+ + E + P + PPGL + +S+ES SS+SSS E Sbjct: 449 RYAKMPDEPLEPGPLPVSTAMPPGLAKSSSESSSEES------------SSESSSEEEEE 496 Query: 1726 AAFESAGEEEGEGEVSASQAAVQAADTDEALRCYIRSKPALYQ 1768 E EEE E S + A + A+ E LR AL Q Sbjct: 497 EDEEDEEEEESESSDSEEERAHRLAELQEQLRAVHEQLAALSQ 539 >gi|46370071 GRB2-associated binding protein 1 isoform a [Homo sapiens] Length = 724 Score = 46.6 bits (109), Expect = 2e-04 Identities = 52/211 (24%), Positives = 80/211 (37%), Gaps = 37/211 (17%) Query: 1243 SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRA-------- 1294 S P AS TD+S+ +P ++ + S ++ LR + Q PRA Sbjct: 361 SIPRTASDTDSSYCIPTAGMSPSRSNTISTVDLNKLRKDASSQDCYD-IPRAFPSDRSSS 419 Query: 1295 --------------SVGNREGNEVAQKFSVIRPQTPPPQTPSSCLTPV--------SPGT 1332 +VG+ E+ + + + P +PP Q SS P+ +PGT Sbjct: 420 LEGFHNHFKVKNVLTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGT 479 Query: 1333 SDGRRQGHRSPSRPHPG--GHPHSSPLAPHPISGDRAHFSRRFLKHSPPG--PSFLNQTP 1388 D G + P H G P + P P P++ R LK G P L P Sbjct: 480 FDFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKGQSPKILRLKP 539 Query: 1389 AGEVVEVGDSDDEQEVASHQANRSPPLDSDP 1419 G +E DS + A+ + + PL+ P Sbjct: 540 HG--LERTDSQTIGDFATRRKVKPAPLEIKP 568 >gi|4557445 regulator of chromosome condensation and BTB domain containing protein 2 [Homo sapiens] Length = 551 Score = 46.2 bits (108), Expect = 3e-04 Identities = 36/104 (34%), Positives = 51/104 (49%), Gaps = 12/104 (11%) Query: 686 NNPHLSDVQFQTDSGEVLYAHKFVLYARCPLLIQYVNNEGF-SAVEDGVLTQRVLLGDVS 744 +NP +D++F D G+ +YAHK +L RC E F S++ED V + + S Sbjct: 389 DNPDTADLKFLVD-GKYIYAHKVLLKIRC---------EHFRSSLEDNE-DDIVEMSEFS 437 Query: 745 TEAARTFLHYLYTADTGLPPGLSSELSSLAHRFGVSELVHLCEQ 788 R FL YLYT L P + L LA + + L LC+Q Sbjct: 438 YPVYRAFLEYLYTDSISLSPEEAVGLLDLATFYRENRLKKLCQQ 481 >gi|211904190 hypothetical protein LOC149478 [Homo sapiens] Length = 291 Score = 45.1 bits (105), Expect = 6e-04 Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 6/107 (5%) Query: 683 AMVNNPHLSDVQFQT-DSGEVLYAHKFVLYARCPLLIQYVNNEGFSAVEDGVLTQRVLLG 741 ++VNNP SDV F + ++AH+ +L RC + + E V V+ L Sbjct: 21 SLVNNPRYSDVCFVVGQERQEVFAHRCLLACRCNFFQRLLGTEPGPGVPSPVV-----LS 75 Query: 742 DVSTEAARTFLHYLYTADTGLPPGLSSELSSLAHRFGVSELVHLCEQ 788 V TEA L +LYT L E+ + A +G+ EL LC Q Sbjct: 76 TVPTEAFLAVLEFLYTNSVKLYRHSVLEVLTAAVEYGLEELRELCLQ 122 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 44.7 bits (104), Expect = 8e-04 Identities = 40/167 (23%), Positives = 61/167 (36%), Gaps = 25/167 (14%) Query: 91 KRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP 150 K T TK + P E P + AP T K EPA + P P Sbjct: 370 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK---------EPAPTTTKSAPTTPKEPSP 420 Query: 151 PVLRETAQNTQTGNQQEPSPNLSREKT----RENVPNSDSQPPPSCLTTAVPSPSKPR-- 204 +E A T +EP+P ++ +E P + +P P+ TT P+P+ P+ Sbjct: 421 TTTKEPAPTT----PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT--TTKKPAPTTPKEP 474 Query: 205 ----TAQLVLQRMQQFKRADPERLRHASEECSLEAAREENVPKDPQE 247 + ++ PE+L + E EE P P+E Sbjct: 475 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 521 Score = 36.2 bits (82), Expect = 0.30 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 15/116 (12%) Query: 91 KRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP 150 K T K T P E P + AP T K+ +PA + E P P Sbjct: 315 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APKKPAPTTPKE-------PAP 366 Query: 151 PVLRETAQNTQTGNQQEPSPNLSRE---KTRENVPNSDSQPPPSCLTTAVPSPSKP 203 +E A T +EPSP +E T ++ P + +P P+ +A +P +P Sbjct: 367 TTPKEPAPTT----TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418 Score = 35.4 bits (80), Expect = 0.51 Identities = 143/784 (18%), Positives = 243/784 (30%), Gaps = 125/784 (15%) Query: 996 EPSQITSEPEEQSGAVRERGLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGS- 1054 EP+ T P+E + + + + AP +P P P +P+ T+ Sbjct: 269 EPAPTT--PKEPAPTTTKEPAPTTTKSAP--TTPKEPAPTTPKKPAPTTPKEPAPTTPKE 324 Query: 1055 -SLSTPRSRGGTSQVGSPTLLSPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKG 1113 + +TP+ T++ +PT P+ K+ T KEP KE Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP--TTPKEPAPTTPKEPAPTTT----- 377 Query: 1114 VLMFPEKSPSIDLTQSNPDHSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISS 1173 E SP+ T P ++++S +++K E T KS + Sbjct: 378 ----KEPSPT---TPKEPAPTTTKSAPTTTK-----------------EPAPTTTKSAPT 413 Query: 1174 DPLEEKKALEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRG 1233 P E P +EP+ + P+ A ++ + Sbjct: 414 TPKEPSPTTTKEPAPT---------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 464 Query: 1234 APWLFCDRE---SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQH 1290 P +E ++P E + T L P TP + + + + LA + Sbjct: 465 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--EKLAPTTPEKPAPTTPEELAPTTPEEP 522 Query: 1291 TPRASVGNREGNEVAQKFSVIRPQTPPPQTPSSCL--TPVSPGTSDGRRQGHRSPSRPHP 1348 TP P+ P P TP + TP P + + +P P P Sbjct: 523 TPTT------------------PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 564 Query: 1349 GGHPHSSPLAPHPISGDRAHFSRRFLKHSP--PGPSFLNQTPAGEVVEVGDSDDEQEVAS 1406 ++P P G + +P P P L T E Sbjct: 565 TTPKETAPTTP---KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621 Query: 1407 HQANRSP-------PLDSDPPIPIDDCCWHME------PLSPIPIDHWNLERTGPLSTSS 1453 A +P P + P P ++ P P P + GP ST+S Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681 Query: 1454 ------------PSRRMNEAADSRDCRSPGLLDTTPIRGS-CTTQRKLQEKSSGAGSLGN 1500 P+ A + +P +T P S +T +E ++ S Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 741 Query: 1501 SRPSFLNSALWDVWDGEEQRP--PETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKV 1558 S P + + P P T PA A KPE T K +++L Sbjct: 742 STPELSAEPTPKALENSPKEPGVPTTKTPA-------ATKPEMTTTAKDKTTERDLRTTP 794 Query: 1559 PITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDS-EDESQSS 1617 T ET ++ + + ++ + TL + + + ++ Sbjct: 795 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 854 Query: 1618 QPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRP----KGPAKTKGPRHQRKHHE 1673 + + +T KP +++ T P +P K P TK P+ + + Sbjct: 855 KKTITTTEIMNKPEETAKPKDRATNSK---ATTPKPQKPTKAPKKPTSTKKPKTMPRVRK 911 Query: 1674 SITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGE 1733 T P+ P LN ++I + T + + +S E E AG Sbjct: 912 PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN------QTPNSKLVEVNPKSEDAGG 965 Query: 1734 EEGE 1737 EGE Sbjct: 966 AEGE 969 Score = 35.0 bits (79), Expect = 0.67 Identities = 96/510 (18%), Positives = 169/510 (33%), Gaps = 98/510 (19%) Query: 93 TKQTATKTKTLQGPAE---KKPPSGSQAPRTKKQRVTKWQASEPAHSV-NGEGGVLASAP 148 T T TL+ PA KKP AP T K+ T +PA + G P Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-PTSTTCDKPAPTTPKGTAPTTPKEP 631 Query: 149 DPPVLRETAQNTQTGNQ----QEPSPNLSREKT-------------------------RE 179 P +E A T G +EP+P ++ +E Sbjct: 632 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 691 Query: 180 NVPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQ-QFKRADPERLRHASEECSLEAARE 238 P + +P P+ T P+P+ P T + +P + + +E + E + E Sbjct: 692 TAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 749 Query: 239 ------ENVPKDPQEEMMAGNVYGLGPPAPESDAAVALTLQQEFARVGASAHDDSLEEKG 292 EN PK+P G P ++ AA + +A D + E Sbjct: 750 PTPKALENSPKEP------------GVPTTKTPAATK-------PEMTTTAKDKTTERD- 789 Query: 293 LFFCQICQKNLSAMNVTRREQHVNRCLDEAEKTLRPS-VPQIPECPICGKPFLTLKSRTS 351 + +A +T+ E++ T + V TLK+ T Sbjct: 790 --LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 847 Query: 352 HLKQCAVKMEVGPQLLLQAVRLQTAQPEGSSSPPMFSFSDHSRGLKR-RGPTSKKEPRKR 410 K K + ++ +TA+P+ ++ + + K + PTS K+P+ Sbjct: 848 APKVTTTKKTITTTEIMNKPE-ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTM 906 Query: 411 RKVDEAPSEDLLVAMALSRSEMEPGAAVPALRLESAFSERIRP----------------- 453 +V + + M + E+ P + + L++ P Sbjct: 907 PRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGA 966 Query: 454 EAENKSRKKKPPVSPPLLLVQDSETTGRQIEDRVAL--LLSEEVELSSTPPLPASRILKE 511 E E +P V P + D + R + + +LS+E + + P+ L+ Sbjct: 967 EGETPHMLLRPHVFMP-EVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRN 1025 Query: 512 G----------WERAGQCPPPPERKQSFLW 531 G W + PP P R+ + +W Sbjct: 1026 GTLVAFRGHYFWMLSPFSPPSPARRITEVW 1055 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 44.7 bits (104), Expect = 8e-04 Identities = 40/167 (23%), Positives = 61/167 (36%), Gaps = 25/167 (14%) Query: 91 KRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP 150 K T TK + P E P + AP T K EPA + P P Sbjct: 411 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK---------EPAPTTTKSAPTTPKEPSP 461 Query: 151 PVLRETAQNTQTGNQQEPSPNLSREKT----RENVPNSDSQPPPSCLTTAVPSPSKPR-- 204 +E A T +EP+P ++ +E P + +P P+ TT P+P+ P+ Sbjct: 462 TTTKEPAPTT----PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT--TTKKPAPTTPKEP 515 Query: 205 ----TAQLVLQRMQQFKRADPERLRHASEECSLEAAREENVPKDPQE 247 + ++ PE+L + E EE P P+E Sbjct: 516 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 562 Score = 36.2 bits (82), Expect = 0.30 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 15/116 (12%) Query: 91 KRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP 150 K T K T P E P + AP T K+ +PA + E P P Sbjct: 356 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APKKPAPTTPKE-------PAP 407 Query: 151 PVLRETAQNTQTGNQQEPSPNLSRE---KTRENVPNSDSQPPPSCLTTAVPSPSKP 203 +E A T +EPSP +E T ++ P + +P P+ +A +P +P Sbjct: 408 TTPKEPAPTT----TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459 Score = 35.4 bits (80), Expect = 0.51 Identities = 143/784 (18%), Positives = 243/784 (30%), Gaps = 125/784 (15%) Query: 996 EPSQITSEPEEQSGAVRERGLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGS- 1054 EP+ T P+E + + + + AP +P P P +P+ T+ Sbjct: 310 EPAPTT--PKEPAPTTTKEPAPTTTKSAP--TTPKEPAPTTPKKPAPTTPKEPAPTTPKE 365 Query: 1055 -SLSTPRSRGGTSQVGSPTLLSPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKG 1113 + +TP+ T++ +PT P+ K+ T KEP KE Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP--TTPKEPAPTTPKEPAPTTT----- 418 Query: 1114 VLMFPEKSPSIDLTQSNPDHSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISS 1173 E SP+ T P ++++S +++K E T KS + Sbjct: 419 ----KEPSPT---TPKEPAPTTTKSAPTTTK-----------------EPAPTTTKSAPT 454 Query: 1174 DPLEEKKALEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRG 1233 P E P +EP+ + P+ A ++ + Sbjct: 455 TPKEPSPTTTKEPAPT---------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 505 Query: 1234 APWLFCDRE---SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQH 1290 P +E ++P E + T L P TP + + + + LA + Sbjct: 506 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--EKLAPTTPEKPAPTTPEELAPTTPEEP 563 Query: 1291 TPRASVGNREGNEVAQKFSVIRPQTPPPQTPSSCL--TPVSPGTSDGRRQGHRSPSRPHP 1348 TP P+ P P TP + TP P + + +P P P Sbjct: 564 TPTT------------------PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 605 Query: 1349 GGHPHSSPLAPHPISGDRAHFSRRFLKHSP--PGPSFLNQTPAGEVVEVGDSDDEQEVAS 1406 ++P P G + +P P P L T E Sbjct: 606 TTPKETAPTTP---KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662 Query: 1407 HQANRSP-------PLDSDPPIPIDDCCWHME------PLSPIPIDHWNLERTGPLSTSS 1453 A +P P + P P ++ P P P + GP ST+S Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722 Query: 1454 ------------PSRRMNEAADSRDCRSPGLLDTTPIRGS-CTTQRKLQEKSSGAGSLGN 1500 P+ A + +P +T P S +T +E ++ S Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 782 Query: 1501 SRPSFLNSALWDVWDGEEQRP--PETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKV 1558 S P + + P P T PA A KPE T K +++L Sbjct: 783 STPELSAEPTPKALENSPKEPGVPTTKTPA-------ATKPEMTTTAKDKTTERDLRTTP 835 Query: 1559 PITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDS-EDESQSS 1617 T ET ++ + + ++ + TL + + + ++ Sbjct: 836 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 895 Query: 1618 QPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRP----KGPAKTKGPRHQRKHHE 1673 + + +T KP +++ T P +P K P TK P+ + + Sbjct: 896 KKTITTTEIMNKPEETAKPKDRATNSK---ATTPKPQKPTKAPKKPTSTKKPKTMPRVRK 952 Query: 1674 SITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGE 1733 T P+ P LN ++I + T + + +S E E AG Sbjct: 953 PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN------QTPNSKLVEVNPKSEDAGG 1006 Query: 1734 EEGE 1737 EGE Sbjct: 1007 AEGE 1010 Score = 35.0 bits (79), Expect = 0.67 Identities = 96/510 (18%), Positives = 169/510 (33%), Gaps = 98/510 (19%) Query: 93 TKQTATKTKTLQGPAE---KKPPSGSQAPRTKKQRVTKWQASEPAHSV-NGEGGVLASAP 148 T T TL+ PA KKP AP T K+ T +PA + G P Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-PTSTTCDKPAPTTPKGTAPTTPKEP 672 Query: 149 DPPVLRETAQNTQTGNQ----QEPSPNLSREKT-------------------------RE 179 P +E A T G +EP+P ++ +E Sbjct: 673 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 732 Query: 180 NVPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQ-QFKRADPERLRHASEECSLEAARE 238 P + +P P+ T P+P+ P T + +P + + +E + E + E Sbjct: 733 TAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 790 Query: 239 ------ENVPKDPQEEMMAGNVYGLGPPAPESDAAVALTLQQEFARVGASAHDDSLEEKG 292 EN PK+P G P ++ AA + +A D + E Sbjct: 791 PTPKALENSPKEP------------GVPTTKTPAATK-------PEMTTTAKDKTTERD- 830 Query: 293 LFFCQICQKNLSAMNVTRREQHVNRCLDEAEKTLRPS-VPQIPECPICGKPFLTLKSRTS 351 + +A +T+ E++ T + V TLK+ T Sbjct: 831 --LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 888 Query: 352 HLKQCAVKMEVGPQLLLQAVRLQTAQPEGSSSPPMFSFSDHSRGLKR-RGPTSKKEPRKR 410 K K + ++ +TA+P+ ++ + + K + PTS K+P+ Sbjct: 889 APKVTTTKKTITTTEIMNKPE-ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTM 947 Query: 411 RKVDEAPSEDLLVAMALSRSEMEPGAAVPALRLESAFSERIRP----------------- 453 +V + + M + E+ P + + L++ P Sbjct: 948 PRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGA 1007 Query: 454 EAENKSRKKKPPVSPPLLLVQDSETTGRQIEDRVAL--LLSEEVELSSTPPLPASRILKE 511 E E +P V P + D + R + + +LS+E + + P+ L+ Sbjct: 1008 EGETPHMLLRPHVFMP-EVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRN 1066 Query: 512 G----------WERAGQCPPPPERKQSFLW 531 G W + PP P R+ + +W Sbjct: 1067 GTLVAFRGHYFWMLSPFSPPSPARRITEVW 1096 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 44.7 bits (104), Expect = 8e-04 Identities = 40/167 (23%), Positives = 61/167 (36%), Gaps = 25/167 (14%) Query: 91 KRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP 150 K T TK + P E P + AP T K EPA + P P Sbjct: 463 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK---------EPAPTTTKSAPTTPKEPSP 513 Query: 151 PVLRETAQNTQTGNQQEPSPNLSREKT----RENVPNSDSQPPPSCLTTAVPSPSKPR-- 204 +E A T +EP+P ++ +E P + +P P+ TT P+P+ P+ Sbjct: 514 TTTKEPAPTT----PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT--TTKKPAPTTPKEP 567 Query: 205 ----TAQLVLQRMQQFKRADPERLRHASEECSLEAAREENVPKDPQE 247 + ++ PE+L + E EE P P+E Sbjct: 568 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 614 Score = 36.2 bits (82), Expect = 0.30 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 15/116 (12%) Query: 91 KRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP 150 K T K T P E P + AP T K+ +PA + E P P Sbjct: 408 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APKKPAPTTPKE-------PAP 459 Query: 151 PVLRETAQNTQTGNQQEPSPNLSRE---KTRENVPNSDSQPPPSCLTTAVPSPSKP 203 +E A T +EPSP +E T ++ P + +P P+ +A +P +P Sbjct: 460 TTPKEPAPTT----TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511 Score = 35.4 bits (80), Expect = 0.51 Identities = 143/784 (18%), Positives = 243/784 (30%), Gaps = 125/784 (15%) Query: 996 EPSQITSEPEEQSGAVRERGLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGS- 1054 EP+ T P+E + + + + AP +P P P +P+ T+ Sbjct: 362 EPAPTT--PKEPAPTTTKEPAPTTTKSAP--TTPKEPAPTTPKKPAPTTPKEPAPTTPKE 417 Query: 1055 -SLSTPRSRGGTSQVGSPTLLSPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKG 1113 + +TP+ T++ +PT P+ K+ T KEP KE Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP--TTPKEPAPTTPKEPAPTTT----- 470 Query: 1114 VLMFPEKSPSIDLTQSNPDHSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISS 1173 E SP+ T P ++++S +++K E T KS + Sbjct: 471 ----KEPSPT---TPKEPAPTTTKSAPTTTK-----------------EPAPTTTKSAPT 506 Query: 1174 DPLEEKKALEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRG 1233 P E P +EP+ + P+ A ++ + Sbjct: 507 TPKEPSPTTTKEPAPT---------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 557 Query: 1234 APWLFCDRE---SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQH 1290 P +E ++P E + T L P TP + + + + LA + Sbjct: 558 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--EKLAPTTPEKPAPTTPEELAPTTPEEP 615 Query: 1291 TPRASVGNREGNEVAQKFSVIRPQTPPPQTPSSCL--TPVSPGTSDGRRQGHRSPSRPHP 1348 TP P+ P P TP + TP P + + +P P P Sbjct: 616 TPTT------------------PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 657 Query: 1349 GGHPHSSPLAPHPISGDRAHFSRRFLKHSP--PGPSFLNQTPAGEVVEVGDSDDEQEVAS 1406 ++P P G + +P P P L T E Sbjct: 658 TTPKETAPTTP---KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714 Query: 1407 HQANRSP-------PLDSDPPIPIDDCCWHME------PLSPIPIDHWNLERTGPLSTSS 1453 A +P P + P P ++ P P P + GP ST+S Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774 Query: 1454 ------------PSRRMNEAADSRDCRSPGLLDTTPIRGS-CTTQRKLQEKSSGAGSLGN 1500 P+ A + +P +T P S +T +E ++ S Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 834 Query: 1501 SRPSFLNSALWDVWDGEEQRP--PETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKV 1558 S P + + P P T PA A KPE T K +++L Sbjct: 835 STPELSAEPTPKALENSPKEPGVPTTKTPA-------ATKPEMTTTAKDKTTERDLRTTP 887 Query: 1559 PITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDS-EDESQSS 1617 T ET ++ + + ++ + TL + + + ++ Sbjct: 888 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 947 Query: 1618 QPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRP----KGPAKTKGPRHQRKHHE 1673 + + +T KP +++ T P +P K P TK P+ + + Sbjct: 948 KKTITTTEIMNKPEETAKPKDRATNSK---ATTPKPQKPTKAPKKPTSTKKPKTMPRVRK 1004 Query: 1674 SITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGE 1733 T P+ P LN ++I + T + + +S E E AG Sbjct: 1005 PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN------QTPNSKLVEVNPKSEDAGG 1058 Query: 1734 EEGE 1737 EGE Sbjct: 1059 AEGE 1062 Score = 35.0 bits (79), Expect = 0.67 Identities = 96/510 (18%), Positives = 169/510 (33%), Gaps = 98/510 (19%) Query: 93 TKQTATKTKTLQGPAE---KKPPSGSQAPRTKKQRVTKWQASEPAHSV-NGEGGVLASAP 148 T T TL+ PA KKP AP T K+ T +PA + G P Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-PTSTTCDKPAPTTPKGTAPTTPKEP 724 Query: 149 DPPVLRETAQNTQTGNQ----QEPSPNLSREKT-------------------------RE 179 P +E A T G +EP+P ++ +E Sbjct: 725 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 784 Query: 180 NVPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQ-QFKRADPERLRHASEECSLEAARE 238 P + +P P+ T P+P+ P T + +P + + +E + E + E Sbjct: 785 TAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 842 Query: 239 ------ENVPKDPQEEMMAGNVYGLGPPAPESDAAVALTLQQEFARVGASAHDDSLEEKG 292 EN PK+P G P ++ AA + +A D + E Sbjct: 843 PTPKALENSPKEP------------GVPTTKTPAATK-------PEMTTTAKDKTTERD- 882 Query: 293 LFFCQICQKNLSAMNVTRREQHVNRCLDEAEKTLRPS-VPQIPECPICGKPFLTLKSRTS 351 + +A +T+ E++ T + V TLK+ T Sbjct: 883 --LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 940 Query: 352 HLKQCAVKMEVGPQLLLQAVRLQTAQPEGSSSPPMFSFSDHSRGLKR-RGPTSKKEPRKR 410 K K + ++ +TA+P+ ++ + + K + PTS K+P+ Sbjct: 941 APKVTTTKKTITTTEIMNKPE-ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTM 999 Query: 411 RKVDEAPSEDLLVAMALSRSEMEPGAAVPALRLESAFSERIRP----------------- 453 +V + + M + E+ P + + L++ P Sbjct: 1000 PRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGA 1059 Query: 454 EAENKSRKKKPPVSPPLLLVQDSETTGRQIEDRVAL--LLSEEVELSSTPPLPASRILKE 511 E E +P V P + D + R + + +LS+E + + P+ L+ Sbjct: 1060 EGETPHMLLRPHVFMP-EVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRN 1118 Query: 512 G----------WERAGQCPPPPERKQSFLW 531 G W + PP P R+ + +W Sbjct: 1119 GTLVAFRGHYFWMLSPFSPPSPARRITEVW 1148 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 44.7 bits (104), Expect = 8e-04 Identities = 40/167 (23%), Positives = 61/167 (36%), Gaps = 25/167 (14%) Query: 91 KRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP 150 K T TK + P E P + AP T K EPA + P P Sbjct: 504 KEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTK---------EPAPTTTKSAPTTPKEPSP 554 Query: 151 PVLRETAQNTQTGNQQEPSPNLSREKT----RENVPNSDSQPPPSCLTTAVPSPSKPR-- 204 +E A T +EP+P ++ +E P + +P P+ TT P+P+ P+ Sbjct: 555 TTTKEPAPTT----PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT--TTKKPAPTTPKEP 608 Query: 205 ----TAQLVLQRMQQFKRADPERLRHASEECSLEAAREENVPKDPQE 247 + ++ PE+L + E EE P P+E Sbjct: 609 APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEE 655 Score = 36.2 bits (82), Expect = 0.30 Identities = 31/116 (26%), Positives = 46/116 (39%), Gaps = 15/116 (12%) Query: 91 KRTKQTATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP 150 K T K T P E P + AP T K+ +PA + E P P Sbjct: 449 KEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APKKPAPTTPKE-------PAP 500 Query: 151 PVLRETAQNTQTGNQQEPSPNLSRE---KTRENVPNSDSQPPPSCLTTAVPSPSKP 203 +E A T +EPSP +E T ++ P + +P P+ +A +P +P Sbjct: 501 TTPKEPAPTT----TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552 Score = 35.4 bits (80), Expect = 0.51 Identities = 143/784 (18%), Positives = 243/784 (30%), Gaps = 125/784 (15%) Query: 996 EPSQITSEPEEQSGAVRERGLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGS- 1054 EP+ T P+E + + + + AP +P P P +P+ T+ Sbjct: 403 EPAPTT--PKEPAPTTTKEPAPTTTKSAP--TTPKEPAPTTPKKPAPTTPKEPAPTTPKE 458 Query: 1055 -SLSTPRSRGGTSQVGSPTLLSPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKG 1113 + +TP+ T++ +PT P+ K+ T KEP KE Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAP--TTPKEPAPTTPKEPAPTTT----- 511 Query: 1114 VLMFPEKSPSIDLTQSNPDHSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISS 1173 E SP+ T P ++++S +++K E T KS + Sbjct: 512 ----KEPSPT---TPKEPAPTTTKSAPTTTK-----------------EPAPTTTKSAPT 547 Query: 1174 DPLEEKKALEISPRSCELFSIIDVDADQEPSQSPPRSEAVLQQEDEGALPENRGSLGRRG 1233 P E P +EP+ + P+ A ++ + Sbjct: 548 TPKEPSPTTTKEPAPT---------TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 598 Query: 1234 APWLFCDRE---SSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQH 1290 P +E ++P E + T L P TP + + + + LA + Sbjct: 599 KPAPTTPKEPAPTTPKETAPTTPKKLTPTTP--EKLAPTTPEKPAPTTPEELAPTTPEEP 656 Query: 1291 TPRASVGNREGNEVAQKFSVIRPQTPPPQTPSSCL--TPVSPGTSDGRRQGHRSPSRPHP 1348 TP P+ P P TP + TP P + + +P P P Sbjct: 657 TPTT------------------PEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAP 698 Query: 1349 GGHPHSSPLAPHPISGDRAHFSRRFLKHSP--PGPSFLNQTPAGEVVEVGDSDDEQEVAS 1406 ++P P G + +P P P L T E Sbjct: 699 TTPKETAPTTP---KGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755 Query: 1407 HQANRSP-------PLDSDPPIPIDDCCWHME------PLSPIPIDHWNLERTGPLSTSS 1453 A +P P + P P ++ P P P + GP ST+S Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815 Query: 1454 ------------PSRRMNEAADSRDCRSPGLLDTTPIRGS-CTTQRKLQEKSSGAGSLGN 1500 P+ A + +P +T P S +T +E ++ S Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE 875 Query: 1501 SRPSFLNSALWDVWDGEEQRP--PETPPPAQMPSAGGAQKPEGLETPKGANRKKNLPPKV 1558 S P + + P P T PA A KPE T K +++L Sbjct: 876 STPELSAEPTPKALENSPKEPGVPTTKTPA-------ATKPEMTTTAKDKTTERDLRTTP 928 Query: 1559 PITPMPQYSIMETPVLKKELDRFGVRPLPKRQMVLKLKEIFQYTHQTLDSDS-EDESQSS 1617 T ET ++ + + ++ + TL + + + ++ Sbjct: 929 ETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTT 988 Query: 1618 QPLLQAPHCQTLASQTYKPSRAGVHAQQEATTGPGAHRP----KGPAKTKGPRHQRKHHE 1673 + + +T KP +++ T P +P K P TK P+ + + Sbjct: 989 KKTITTTEIMNKPEETAKPKDRATNSK---ATTPKPQKPTKAPKKPTSTKKPKTMPRVRK 1045 Query: 1674 SITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSSSSCEFGAAFESAGE 1733 T P+ P LN ++I + T + + +S E E AG Sbjct: 1046 PKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPN------QTPNSKLVEVNPKSEDAGG 1099 Query: 1734 EEGE 1737 EGE Sbjct: 1100 AEGE 1103 Score = 35.0 bits (79), Expect = 0.67 Identities = 96/510 (18%), Positives = 169/510 (33%), Gaps = 98/510 (19%) Query: 93 TKQTATKTKTLQGPAE---KKPPSGSQAPRTKKQRVTKWQASEPAHSV-NGEGGVLASAP 148 T T TL+ PA KKP AP T K+ T +PA + G P Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKE-PTSTTCDKPAPTTPKGTAPTTPKEP 765 Query: 149 DPPVLRETAQNTQTGNQ----QEPSPNLSREKT-------------------------RE 179 P +E A T G +EP+P ++ +E Sbjct: 766 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 825 Query: 180 NVPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQ-QFKRADPERLRHASEECSLEAARE 238 P + +P P+ T P+P+ P T + +P + + +E + E + E Sbjct: 826 TAPTTPKEPAPT--TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAE 883 Query: 239 ------ENVPKDPQEEMMAGNVYGLGPPAPESDAAVALTLQQEFARVGASAHDDSLEEKG 292 EN PK+P G P ++ AA + +A D + E Sbjct: 884 PTPKALENSPKEP------------GVPTTKTPAATK-------PEMTTTAKDKTTERD- 923 Query: 293 LFFCQICQKNLSAMNVTRREQHVNRCLDEAEKTLRPS-VPQIPECPICGKPFLTLKSRTS 351 + +A +T+ E++ T + V TLK+ T Sbjct: 924 --LRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTL 981 Query: 352 HLKQCAVKMEVGPQLLLQAVRLQTAQPEGSSSPPMFSFSDHSRGLKR-RGPTSKKEPRKR 410 K K + ++ +TA+P+ ++ + + K + PTS K+P+ Sbjct: 982 APKVTTTKKTITTTEIMNKPE-ETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTM 1040 Query: 411 RKVDEAPSEDLLVAMALSRSEMEPGAAVPALRLESAFSERIRP----------------- 453 +V + + M + E+ P + + L++ P Sbjct: 1041 PRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGA 1100 Query: 454 EAENKSRKKKPPVSPPLLLVQDSETTGRQIEDRVAL--LLSEEVELSSTPPLPASRILKE 511 E E +P V P + D + R + + +LS+E + + P+ L+ Sbjct: 1101 EGETPHMLLRPHVFMP-EVTPDMDYLPRVPNQGIIINPMLSDETNICNGKPVDGLTTLRN 1159 Query: 512 G----------WERAGQCPPPPERKQSFLW 531 G W + PP P R+ + +W Sbjct: 1160 GTLVAFRGHYFWMLSPFSPPSPARRITEVW 1189 >gi|95147555 microtubule-associated protein 1A [Homo sapiens] Length = 2803 Score = 44.3 bits (103), Expect = 0.001 Identities = 29/68 (42%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 545 FYTARLVPPLVPQRPAQGLMQEP--VPPLVPPEHSELSERRSPALHGT-PTAGCGSRGPS 601 F A L P VP RP G EP PP VPP LS+ SP L+G + R PS Sbjct: 2033 FSYAALAGPTVPPRPEPGPSMEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSPS 2092 Query: 602 PSASQREH 609 P S R H Sbjct: 2093 PKESGRSH 2100 Score = 32.3 bits (72), Expect = 4.4 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 5/97 (5%) Query: 793 TDSEGKPWEEK---EAENCESRAENFQELLRSMWADEEEEAETLLKSKDHEEDQENVNEA 849 T+ E WEEK EAE R E +E + D E+AE + H D+E + Sbjct: 616 TEEEKDTWEEKKQREAERLPDRTEAREESEPEVKEDVIEKAELEEMEEVHPSDEEEEDAT 675 Query: 850 EMEEIYE-FAATQRKLLQEERAAGAGEDADWLEGGSP 885 + E Y+ K+ R A G + L+G +P Sbjct: 676 KAEGFYQKHMQEPLKVTPRSREAFGGRELG-LQGKAP 711 Score = 32.3 bits (72), Expect = 4.4 Identities = 42/164 (25%), Positives = 66/164 (40%), Gaps = 23/164 (14%) Query: 112 PSGSQAPRTKKQRVTKWQASEPAHSVNGEGG-VLASAPDPPVLRETAQNTQTGNQQEPSP 170 P+ Q P + R S P S+ G LA AP PP T+ E + Sbjct: 2175 PAPPQLPSPAEPR------SAPCGSLAFSGDRALALAPGPPT------RTRHDEYLEVTK 2222 Query: 171 NLSREKTRENVPNSDSQPPPSCLTTAVPSPSKPRTAQLVLQRMQQFKRADPERLRHASEE 230 S + + +P+ S P L + +P P+ P ++ A + +E Sbjct: 2223 APSLDSSLPQLPSPSSPGAP--LLSNLPRPASPALSE------GSSSEATTPVISSVAER 2274 Query: 231 CS--LEAAREENVPKDPQEEMMAGNVYGLGPPAPESDAAVALTL 272 S LEAA +E+ DP E A +++ L P +P A++ L L Sbjct: 2275 FSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLAL 2318 Score = 31.2 bits (69), Expect = 9.7 Identities = 29/144 (20%), Positives = 66/144 (45%), Gaps = 17/144 (11%) Query: 1101 KERRSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSRSQKSSSKLNEEDEVILLLDSDEE 1160 +++ LE ++K + EK +++ P+ ++ + L ++D+ L D++ Sbjct: 1423 EQKDKALEPKDKDL---EEKDKALEQKDKIPEEKDKALEQKDTALEQKDKA--LEPKDKD 1477 Query: 1161 LELEQTKMKSISSDPLEEKKALEISPRSCELFSIIDVDAD------QEPSQSPPRSEAVL 1214 LE + ++ P E+ KAL+ RS E + D A+ ++ ++P + Sbjct: 1478 LEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQ 1537 Query: 1215 QQED------EGALPENRGSLGRR 1232 +Q+D + AL + +LG++ Sbjct: 1538 EQKDKVSEKKDQALEQKYWALGQK 1561 >gi|19924097 synapsin I isoform Ib [Homo sapiens] Length = 669 Score = 44.3 bits (103), Expect = 0.001 Identities = 61/246 (24%), Positives = 75/246 (30%), Gaps = 48/246 (19%) Query: 1314 QTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPHPISGDRAHFSRRF 1373 Q PPPQ P PG +RQG RP P G H S L P S Sbjct: 459 QRPPPQGG-----PPQPGPGP-QRQGPPLQQRPPPQGQQHLSGLGPPAGSP--------- 503 Query: 1374 LKHSPPGPSFLNQTPAGEVVEVGDSDDEQE-----------VASHQANRSPPLDSDPPIP 1422 L P P+ Q PA + Q A A+ SP + PP Sbjct: 504 LPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQAGPP-- 561 Query: 1423 IDDCCWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSC 1482 P P G P + A +R G P G Sbjct: 562 --QATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAG---PVPRTGPP 616 Query: 1483 TTQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGL 1542 TTQ Q + SG G G +P Q+P + PP +AGG P+ Sbjct: 617 TTQ---QPRPSGPGPAGRPKPQL------------AQKPSQDVPPPATAAAGGPPHPQLK 661 Query: 1543 ETPKGA 1548 +P A Sbjct: 662 ASPAQA 667 Score = 37.4 bits (85), Expect = 0.14 Identities = 20/63 (31%), Positives = 28/63 (44%) Query: 1650 GPGAHRPKGPAKTKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDG 1709 GPG R P + + P ++H + PP+ SP + P Q PASQ + T G Sbjct: 471 GPGPQRQGPPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQG 530 Query: 1710 SDS 1712 S Sbjct: 531 RQS 533 Score = 36.6 bits (83), Expect = 0.23 Identities = 44/191 (23%), Positives = 68/191 (35%), Gaps = 17/191 (8%) Query: 1371 RRFLKHSPPGPSFLNQTPAGEVVEVGDSDDEQEVASHQANRSPPLDSDPPIPIDDCCWHM 1430 R+ + + PG QTP+ + +G +Q A A + PP PP P Sbjct: 420 RQRQRDASPGRGSHGQTPSPGALPLGRQTSQQP-AGPPAQQRPPPQGGPPQPGPGPQRQG 478 Query: 1431 EPLS--PIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSPGLLDTTPIRGSCTTQRKL 1488 PL P P +L GP + S +R+ + + P P +G R + Sbjct: 479 PPLQQRPPPQGQQHLSGLGPPAGSPLPQRLPSPTSAP--QQPASQAAPPTQGQGRQSRPV 536 Query: 1489 QEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQMPSAGGAQKPEGLETPKGA 1548 + G G+ +RP S QR P + S G P+ P G Sbjct: 537 ---AGGPGAPPAARPPASPSP---------QRQAGPPQATRQTSVSGPAPPKASGAPPGG 584 Query: 1549 NRKKNLPPKVP 1559 +++ P K P Sbjct: 585 QQRQGPPQKPP 595 Score = 32.0 bits (71), Expect = 5.7 Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 13/115 (11%) Query: 97 ATKTKTLQGPAEKKPPSGSQAPRTKKQRVTKWQASEPAHSVNGEGGVLASAPDP-PVLRE 155 AT+ ++ GPA PP S AP +QR P G G A PV R Sbjct: 563 ATRQTSVSGPA---PPKASGAPPGGQQR------QGPPQKPPGPAGPTRQASQAGPVPRT 613 Query: 156 TAQNTQTGNQQEPSPNLSREKTRENVPNSDSQPPPSCLTTAVPSP---SKPRTAQ 207 TQ P P + P+ D PP + P P + P AQ Sbjct: 614 GPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLKASPAQAQ 668 >gi|92091572 dedicator of cytokinesis 4 [Homo sapiens] Length = 1966 Score = 43.9 bits (102), Expect = 0.001 Identities = 76/332 (22%), Positives = 123/332 (37%), Gaps = 39/332 (11%) Query: 1241 RESSPSEASTTDTSWLVPATPLASRSRDCSSQTQISSLRSGLAVQAVTQHTPRASVGNRE 1300 R S+P+ S T + +PL+ + + S + +SS S Q V N + Sbjct: 1612 RNSAPASVSPDGTRVIPRRSPLSYPAVNRYSSSSLSSQASAEVSNITGQSESSDEVFNMQ 1671 Query: 1301 GNEVAQKFSVIRPQTPPPQTPSSCLTPVSPGTSDGRRQGHRSPSRPHPGGHPHSSPLAPH 1360 + S +P + + SP SD + + R S P P S + P Sbjct: 1672 PSPSTSSLSSTHSASPNVTSSAPSSARASPLLSD-KHKHSRENSCLSPRERP-CSAIYPT 1729 Query: 1361 PISGDRA----HFSRRFLKHSPPGPS----FLNQTPAGEVVEVGDSDDEQEVASHQANRS 1412 P+ + H L S P S +N TP+ ++ G + + ++ S Sbjct: 1730 PVEPSQRMLFNHIGDGALPRSDPNLSAPEKAVNPTPSSWSLDSG--KEAKNMSDSGKLIS 1787 Query: 1413 PPLDSDPPIPIDDC--CWHMEPLSPIPIDHWNLERTGPLSTSSPSRRMNEAADSRDCRSP 1470 PP+ PP P H +SP P L+ + T SP + SP Sbjct: 1788 PPV---PPRPTQTASPARHTTSVSPSPAGRSPLKGSVQSFTPSPV----------EYHSP 1834 Query: 1471 GLLDTTPIRGSCTTQRKLQEKSSGAGSLGNSRPSFLNSALWDVWDGEEQRPPETPPPAQM 1530 GL+ +P+ SSG SL SR S ++ ++ E+ P P P + Sbjct: 1835 GLISNSPVLSG--------SYSSGISSL--SRCSTSETSGFENQVNEQSAPLPVPVPVPV 1884 Query: 1531 PSAGGAQ--KPEGLETPKGANRKKNLPPKVPI 1560 PS GG + + E P + ++ L VP+ Sbjct: 1885 PSYGGEEPVRKESKTPPPYSVYERTLRRPVPL 1916 >gi|4507161 SRY-box 11 [Homo sapiens] Length = 441 Score = 43.9 bits (102), Expect = 0.001 Identities = 44/163 (26%), Positives = 63/163 (38%), Gaps = 22/163 (13%) Query: 1607 DSDSEDESQSSQPLLQAPHCQTLASQTYK-------PSRAGVHAQQEATTGPGAHRPKGP 1659 + D EDE Q LLQ P Q SQ + P+ + + E+ G + Sbjct: 242 EPDEEDEEPPHQQLLQPPGQQP--SQLLRRYNVAKVPASPTLSSSAESPEGASLYDEVRA 299 Query: 1660 AKTKGPRHQRKHHESITPPSRSPTKEAPPGLNDDAQIPASQESVATSVDGSDSSLSSQSS 1719 T G + + S ++ TK+ PP L A PAS SV+TS S S S S Sbjct: 300 GATSGAGGGSRLYYSF----KNITKQHPPPLAQPALSPASSRSVSTSSSSSSGSSSGSSG 355 Query: 1720 S---------SCEFGAAFESAGEEEGEGEVSASQAAVQAADTD 1753 S F + SA E++ G +A ++ D D Sbjct: 356 EDADDLMFDLSLNFSQSAHSASEQQLGGGAAAGNLSLSLVDKD 398 >gi|239743602 PREDICTED: hypothetical protein XP_002342903 [Homo sapiens] Length = 675 Score = 43.5 bits (101), Expect = 0.002 Identities = 112/495 (22%), Positives = 175/495 (35%), Gaps = 75/495 (15%) Query: 850 EMEEIYEFAATQ--RKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQWDKVEEME 907 E +++ E AA + R L E+ AGA E + L +P W + E Sbjct: 16 EAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPC-------------WFRPGYPE 62 Query: 908 PLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSSCSSPSRDCQA 967 + ++ A +G P + S A AP P G+ + + Sbjct: 63 AKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPP----GYPEAKKVAEEAAL 118 Query: 968 ERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQSGAVRERGLEVSHRLAPWQA 1027 E E LP A + + S I +EP+ + AV W Sbjct: 119 EAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPA----------WPK 168 Query: 1028 SPPHPCRFLLGPPQGGS-------PRGSHHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPS 1080 C F P Q GS PR + SG +S PR R + SP L++ + Sbjct: 169 MVTESCYF---PAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDA 225 Query: 1081 KQKRDRSILTLSK--EPGHQKGKER-RSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSR 1137 K+ R S S+ + G Q GK R RS + C+ S I S P S + Sbjct: 226 KRTRVASSSQRSRGSKVGRQPGKTRNRSGMACKTTAT----TSSKRIVRRASLPSLSLKK 281 Query: 1138 SQKSSSKLNEEDEVI----LLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFS 1193 S + V+ L L ++E L+ +K ++ EEK A + SP + Sbjct: 282 PIILRSSGCQVPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLN 341 Query: 1194 IIDVDADQ----EPSQSPPRSEAVLQQE------DEGALPENRGSL---GRRGAPWLFCD 1240 ++ + PS P S A L + L EN R G LF Sbjct: 342 VVLNTLKRLKGLTPSSMPGLSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTG 401 Query: 1241 RESSPSEAS-----TTDTSWLVPATPLASRSRDCS---SQTQISSLRSGLAVQAVTQHTP 1292 + P ++S T +LV ++ R + C + + S + G V+Q+T Sbjct: 402 QGKGPGDSSCRVCCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGG----RVSQYTC 457 Query: 1293 RASVGNREGNEVAQK 1307 A+ G +VA++ Sbjct: 458 CAAAPGSVGCQVAKQ 472 >gi|239743600 PREDICTED: hypothetical protein XP_002342902 [Homo sapiens] Length = 675 Score = 43.5 bits (101), Expect = 0.002 Identities = 112/495 (22%), Positives = 175/495 (35%), Gaps = 75/495 (15%) Query: 850 EMEEIYEFAATQ--RKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQWDKVEEME 907 E +++ E AA + R L E+ AGA E + L +P W + E Sbjct: 16 EAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPC-------------WFRPGYPE 62 Query: 908 PLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSSCSSPSRDCQA 967 + ++ A +G P + S A AP P G+ + + Sbjct: 63 AKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPP----GYPEAKKVAEEAAL 118 Query: 968 ERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQSGAVRERGLEVSHRLAPWQA 1027 E E LP A + + S I +EP+ + AV W Sbjct: 119 EAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPA----------WPK 168 Query: 1028 SPPHPCRFLLGPPQGGS-------PRGSHHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPS 1080 C F P Q GS PR + SG +S PR R + SP L++ + Sbjct: 169 MVTESCYF---PAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDA 225 Query: 1081 KQKRDRSILTLSK--EPGHQKGKER-RSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSR 1137 K+ R S S+ + G Q GK R RS + C+ S I S P S + Sbjct: 226 KRTRVASSSQRSRGSKVGRQPGKTRNRSGMACKTTAT----TSSKRIVRRASLPSLSLKK 281 Query: 1138 SQKSSSKLNEEDEVI----LLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFS 1193 S + V+ L L ++E L+ +K ++ EEK A + SP + Sbjct: 282 PIILRSSGCQVPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLN 341 Query: 1194 IIDVDADQ----EPSQSPPRSEAVLQQE------DEGALPENRGSL---GRRGAPWLFCD 1240 ++ + PS P S A L + L EN R G LF Sbjct: 342 VVLNTLKRLKGLTPSSMPGLSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTG 401 Query: 1241 RESSPSEAS-----TTDTSWLVPATPLASRSRDCS---SQTQISSLRSGLAVQAVTQHTP 1292 + P ++S T +LV ++ R + C + + S + G V+Q+T Sbjct: 402 QGKGPGDSSCRVCCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGG----RVSQYTC 457 Query: 1293 RASVGNREGNEVAQK 1307 A+ G +VA++ Sbjct: 458 CAAAPGSVGCQVAKQ 472 >gi|239743598 PREDICTED: hypothetical protein XP_002342901 [Homo sapiens] Length = 675 Score = 43.5 bits (101), Expect = 0.002 Identities = 112/495 (22%), Positives = 175/495 (35%), Gaps = 75/495 (15%) Query: 850 EMEEIYEFAATQ--RKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQWDKVEEME 907 E +++ E AA + R L E+ AGA E + L +P W + E Sbjct: 16 EAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPC-------------WFRPGYPE 62 Query: 908 PLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSSCSSPSRDCQA 967 + ++ A +G P + S A AP P G+ + + Sbjct: 63 AKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPP----GYPEAKKVAEEAAL 118 Query: 968 ERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQSGAVRERGLEVSHRLAPWQA 1027 E E LP A + + S I +EP+ + AV W Sbjct: 119 EAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPA----------WPK 168 Query: 1028 SPPHPCRFLLGPPQGGS-------PRGSHHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPS 1080 C F P Q GS PR + SG +S PR R + SP L++ + Sbjct: 169 MVTESCYF---PAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDA 225 Query: 1081 KQKRDRSILTLSK--EPGHQKGKER-RSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSR 1137 K+ R S S+ + G Q GK R RS + C+ S I S P S + Sbjct: 226 KRTRVASSSQRSRGSKVGRQPGKTRNRSGMACKTTAT----TSSKRIVRRASLPSLSLKK 281 Query: 1138 SQKSSSKLNEEDEVI----LLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFS 1193 S + V+ L L ++E L+ +K ++ EEK A + SP + Sbjct: 282 PIILRSSGCQVPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLN 341 Query: 1194 IIDVDADQ----EPSQSPPRSEAVLQQE------DEGALPENRGSL---GRRGAPWLFCD 1240 ++ + PS P S A L + L EN R G LF Sbjct: 342 VVLNTLKRLKGLTPSSMPGLSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTG 401 Query: 1241 RESSPSEAS-----TTDTSWLVPATPLASRSRDCS---SQTQISSLRSGLAVQAVTQHTP 1292 + P ++S T +LV ++ R + C + + S + G V+Q+T Sbjct: 402 QGKGPGDSSCRVCCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGG----RVSQYTC 457 Query: 1293 RASVGNREGNEVAQK 1307 A+ G +VA++ Sbjct: 458 CAAAPGSVGCQVAKQ 472 >gi|239743596 PREDICTED: hypothetical protein XP_002342900 [Homo sapiens] Length = 675 Score = 43.5 bits (101), Expect = 0.002 Identities = 112/495 (22%), Positives = 175/495 (35%), Gaps = 75/495 (15%) Query: 850 EMEEIYEFAATQ--RKLLQEERAAGAGEDADWLEGGSPVSGQLLAGVQVQKQWDKVEEME 907 E +++ E AA + R L E+ AGA E + L +P W + E Sbjct: 16 EAKKVAEEAALEASRHLGGEQSQAGAPEGSKMLRATAPC-------------WFRPGYPE 62 Query: 908 PLEPGRDEAATTWEKMGQCALPPPQGQHSGARGAEAPEQEAPEEALGHSSCSSPSRDCQA 967 + ++ A +G P + S A AP P G+ + + Sbjct: 63 AKKVAKEAAPEASRHLGAEQSPAGAPEGSKMLRATAPCWFPP----GYPEAKKVAEEAAL 118 Query: 968 ERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQSGAVRERGLEVSHRLAPWQA 1027 E E LP A + + S I +EP+ + AV W Sbjct: 119 EAPEFPLPSHQPAQSFGLWVPQMHKQASAFVDIQAEPQNRGPAVPPA----------WPK 168 Query: 1028 SPPHPCRFLLGPPQGGS-------PRGSHHTSGSSLSTPRSRGGTSQVGSPTLLSPAVPS 1080 C F P Q GS PR + SG +S PR R + SP L++ + Sbjct: 169 MVTESCYF---PAQRGSACRLPAAPRLTERPSGVRISAPRKRKTIAHSSSPCLVTGYTDA 225 Query: 1081 KQKRDRSILTLSK--EPGHQKGKER-RSVLECRNKGVLMFPEKSPSIDLTQSNPDHSSSR 1137 K+ R S S+ + G Q GK R RS + C+ S I S P S + Sbjct: 226 KRTRVASSSQRSRGSKVGRQPGKTRNRSGMACKTTAT----TSSKRIVRRASLPSLSLKK 281 Query: 1138 SQKSSSKLNEEDEVI----LLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCELFS 1193 S + V+ L L ++E L+ +K ++ EEK A + SP + Sbjct: 282 PIILRSSGCQVPTVLRRGYLQLFTEECLKFCASKQEAEEKALNEEKVAYDCSPNKNRYLN 341 Query: 1194 IIDVDADQ----EPSQSPPRSEAVLQQE------DEGALPENRGSL---GRRGAPWLFCD 1240 ++ + PS P S A L + L EN R G LF Sbjct: 342 VVLNTLKRLKGLTPSSMPGLSRAALYSRLQEFLLTQDQLKENGYPFPHPERPGGAVLFTG 401 Query: 1241 RESSPSEAS-----TTDTSWLVPATPLASRSRDCS---SQTQISSLRSGLAVQAVTQHTP 1292 + P ++S T +LV ++ R + C + + S + G V+Q+T Sbjct: 402 QGKGPGDSSCRVCCRCGTEYLVSSSGRCVRDQLCYYHWGRVRSSQVAGG----RVSQYTC 457 Query: 1293 RASVGNREGNEVAQK 1307 A+ G +VA++ Sbjct: 458 CAAAPGSVGCQVAKQ 472 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 43.5 bits (101), Expect = 0.002 Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 28/227 (12%) Query: 757 TADTGLPPGLSSELSSLAHRFGVSELVHLCEQVPIATDSEGKPWEEKEAENCESRAENFQ 816 T G PP L +L+ ++++ + E + EE+E E E E + Sbjct: 865 TPGGGGPPALEEDLT----------VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEE 914 Query: 817 ELLRSMWADEEEEAETLLKSKDHEEDQENVNEAEMEEIYEFAATQRKLLQEERAAGAGED 876 E + +EEEE E ++ EE++ + E E EE E + + L+E G Sbjct: 915 EDEEEYFEEEEEEEEEF--EEEFEEEEGELEEEEEEEDEE----EEEELEEVEDLEFGTA 968 Query: 877 ADWLEGGSPVSGQLLAGVQVQKQWDKVEEMEPLEPG---RDEAATTWEKMGQCALP---- 929 +E G+P L + + KV+ EPG E T E+ G P Sbjct: 969 GGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAP 1028 Query: 930 ---PPQGQHSGARGAEAPEQEAPEEALGHSSCSSPSRDCQAERKEGS 973 P QG+ R E+P P + L S+P + E ++GS Sbjct: 1029 EALPSQGEVE--REGESPAAGPPPQELVEEEPSAPPTLLEEETEDGS 1073 Score = 31.6 bits (70), Expect = 7.4 Identities = 66/321 (20%), Positives = 105/321 (32%), Gaps = 77/321 (23%) Query: 924 GQCALPPPQGQHSGARGAEAP---------------------EQEAPEEALGHSSCSSPS 962 G LPPPQ G G P E+E EE Sbjct: 851 GPVTLPPPQLVPEGTPGGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDF 910 Query: 963 RDCQAERKEGSLPHSDDAGDYEQLFSSTQGEISEPSQITSEPEEQ------------SGA 1010 + + + +E ++ ++E+ F +GE+ E + E EE+ +G Sbjct: 911 EEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGG 970 Query: 1011 VRERGLEVSHRLAPWQASPPHPCRFLLGPPQGGSPRGSHHTSGSSLSTPRSRGGTSQVGS 1070 E G L P P P + P P T RG + + Sbjct: 971 EVEEGAPPPPTLPPALPPPESPPKVQPEP----EPEPGLLLEVEEPGTEEERGADT---A 1023 Query: 1071 PTLLSPAVPSKQKRDRSILTLSKEPGHQKGKERRSVLECRNKGVLMFPEKSPSIDLTQSN 1130 PTL A+PS+ + +R + + P Q+ E+ PS + Sbjct: 1024 PTLAPEALPSQGEVEREGESPAAGPPPQE-----------------LVEEEPS-----AP 1061 Query: 1131 PDHSSSRSQKSSSKLNEEDEVILLLDSDEELELEQTKMKSISSDPLEEKKALEISPRSCE 1190 P ++ S K+ E ++EE+E E ++ L+EK E + Sbjct: 1062 PTLLEEETEDGSDKVQPPPET----PAEEEMETE------TEAEALQEK---EQDDTAAM 1108 Query: 1191 LFSIIDVDADQEPSQSPPRSE 1211 L ID D E + PP +E Sbjct: 1109 LADFIDCPPDDE--KPPPPTE 1127 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.128 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 88,035,816 Number of Sequences: 37866 Number of extensions: 5226146 Number of successful extensions: 30619 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 49 Number of HSP's successfully gapped in prelim test: 899 Number of HSP's that attempted gapping in prelim test: 25456 Number of HSP's gapped (non-prelim): 6197 length of query: 1834 length of database: 18,247,518 effective HSP length: 117 effective length of query: 1717 effective length of database: 13,817,196 effective search space: 23724125532 effective search space used: 23724125532 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.