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Search of human proteins with 62177127
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
(1858 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62177127 myosin heavy chain Myr 8 [Homo sapiens] 3739 0.0
gi|134288915 myosin IIIB isoform 1 [Homo sapiens] 443 e-124
gi|134288892 myosin IIIB isoform 2 [Homo sapiens] 443 e-124
gi|145275208 myosin IIIA [Homo sapiens] 442 e-123
gi|153792764 hypothetical protein LOC57624 [Homo sapiens] 357 6e-98
gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens] 357 6e-98
gi|154354979 myosin X [Homo sapiens] 357 6e-98
gi|118402590 myosin XV [Homo sapiens] 352 2e-96
gi|122937512 myosin VIIB [Homo sapiens] 352 2e-96
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 352 3e-96
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 352 3e-96
gi|189083798 myosin VIIA isoform 1 [Homo sapiens] 352 3e-96
gi|27544941 myosin IF [Homo sapiens] 332 2e-90
gi|51100974 myosin ID [Homo sapiens] 331 4e-90
gi|124494247 myosin IC isoform b [Homo sapiens] 329 1e-89
gi|124494238 myosin IC isoform a [Homo sapiens] 329 1e-89
gi|124494240 myosin IC isoform c [Homo sapiens] 329 1e-89
gi|153945715 myosin VC [Homo sapiens] 328 3e-89
gi|215982794 myosin VA isoform 2 [Homo sapiens] 326 1e-88
gi|215982791 myosin VA isoform 1 [Homo sapiens] 326 1e-88
gi|55956916 myosin IE [Homo sapiens] 326 1e-88
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 314 6e-85
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 314 6e-85
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 311 4e-84
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 311 4e-84
gi|122937345 myosin VB [Homo sapiens] 310 6e-84
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 306 9e-83
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 306 1e-82
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 305 3e-82
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 305 4e-82
>gi|62177127 myosin heavy chain Myr 8 [Homo sapiens]
Length = 1858
Score = 3739 bits (9697), Expect = 0.0
Identities = 1858/1858 (100%), Positives = 1858/1858 (100%)
Query: 1 MEIDQCLLESLPLGQRQRLVKRMRCEQIKAYYEREKAFQKQEGFLKRLKHAKNPKVHFNL 60
MEIDQCLLESLPLGQRQRLVKRMRCEQIKAYYEREKAFQKQEGFLKRLKHAKNPKVHFNL
Sbjct: 1 MEIDQCLLESLPLGQRQRLVKRMRCEQIKAYYEREKAFQKQEGFLKRLKHAKNPKVHFNL 60
Query: 61 TDMLQDAIIHHNDKEVLRLLKEGADPHTLVSSGGSLLHLCARYDNAFIAEILIDRGVNVN 120
TDMLQDAIIHHNDKEVLRLLKEGADPHTLVSSGGSLLHLCARYDNAFIAEILIDRGVNVN
Sbjct: 61 TDMLQDAIIHHNDKEVLRLLKEGADPHTLVSSGGSLLHLCARYDNAFIAEILIDRGVNVN 120
Query: 121 HQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPLDYAVEGTESSSILLTYL 180
HQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPLDYAVEGTESSSILLTYL
Sbjct: 121 HQDEDFWTPMHIACACDNPDIVLLLVLAGANVLLQDVNGNIPLDYAVEGTESSSILLTYL 180
Query: 181 DENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGVTLLHMACASGYKEVVSL 240
DENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGVTLLHMACASGYKEVVSL
Sbjct: 181 DENGVDLTSLRQMKLQRPMSMLTDVKHFLSSGGNVNEKNDEGVTLLHMACASGYKEVVSL 240
Query: 241 ILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNEEKASDIAASEFI 300
ILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNEEKASDIAASEFI
Sbjct: 241 ILEHGGDLNIVDDQYWTPLHLAAKYGQTNLVKLLLMHQANPHLVNCNEEKASDIAASEFI 300
Query: 301 EEMLLKAEIAWEEKMKEPLSASTLAQEEPYEEIIHDLPVLSSKLSPLVLPIAKQDSLLEK 360
EEMLLKAEIAWEEKMKEPLSASTLAQEEPYEEIIHDLPVLSSKLSPLVLPIAKQDSLLEK
Sbjct: 301 EEMLLKAEIAWEEKMKEPLSASTLAQEEPYEEIIHDLPVLSSKLSPLVLPIAKQDSLLEK 360
Query: 361 DIMFKDATKGLCKQQSQDSIPENPMMSGSTKPEQVKLMPPAPNDDLATLSELNDGSLLYE 420
DIMFKDATKGLCKQQSQDSIPENPMMSGSTKPEQVKLMPPAPNDDLATLSELNDGSLLYE
Sbjct: 361 DIMFKDATKGLCKQQSQDSIPENPMMSGSTKPEQVKLMPPAPNDDLATLSELNDGSLLYE 420
Query: 421 IQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERA 480
IQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERA
Sbjct: 421 IQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERA 480
Query: 481 FHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRATLDSRFKHVVCILEAFG 540
FHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRATLDSRFKHVVCILEAFG
Sbjct: 481 FHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRATLDSRFKHVVCILEAFG 540
Query: 541 HAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLM 600
HAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLM
Sbjct: 541 HAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLM 600
Query: 601 DGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVE 660
DGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVE
Sbjct: 601 DGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVE 660
Query: 661 NLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFK 720
NLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFK
Sbjct: 661 NLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFK 720
Query: 721 GDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIF 780
GDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIF
Sbjct: 721 GDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIF 780
Query: 781 GFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDF 840
GFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDF
Sbjct: 781 GFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDF 840
Query: 841 FFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGT 900
FFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGT
Sbjct: 841 FFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGT 900
Query: 901 AFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAY 960
AFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAY
Sbjct: 901 AFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAY 960
Query: 961 PSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQL 1020
PSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQL
Sbjct: 961 PSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQL 1020
Query: 1021 RKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPV 1080
RKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPV
Sbjct: 1021 RKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPV 1080
Query: 1081 RLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQCKLQGWQMGVRKVFLKYWHADQL 1140
RLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQCKLQGWQMGVRKVFLKYWHADQL
Sbjct: 1081 RLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQCKLQGWQMGVRKVFLKYWHADQL 1140
Query: 1141 NDLCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQEVTSINSFLQNTEDMGLKTYDALV 1200
NDLCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQEVTSINSFLQNTEDMGLKTYDALV
Sbjct: 1141 NDLCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQEVTSINSFLQNTEDMGLKTYDALV 1200
Query: 1201 IQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEGSKRTDDKSGPRHFHPSSMSVCAAV 1260
IQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEGSKRTDDKSGPRHFHPSSMSVCAAV
Sbjct: 1201 IQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEGSKRTDDKSGPRHFHPSSMSVCAAV 1260
Query: 1261 DGLGQCLVGPSIWSPSLHSVFSMDDSSSLPSPRKQPPPKPKRDPNTRLSASYEAVSACLS 1320
DGLGQCLVGPSIWSPSLHSVFSMDDSSSLPSPRKQPPPKPKRDPNTRLSASYEAVSACLS
Sbjct: 1261 DGLGQCLVGPSIWSPSLHSVFSMDDSSSLPSPRKQPPPKPKRDPNTRLSASYEAVSACLS 1320
Query: 1321 AAREAANEALARPRPHSDDYSTMKKIPPRKPKRSPNTKLSGSYEEISGSRPGDARPAGAP 1380
AAREAANEALARPRPHSDDYSTMKKIPPRKPKRSPNTKLSGSYEEISGSRPGDARPAGAP
Sbjct: 1321 AAREAANEALARPRPHSDDYSTMKKIPPRKPKRSPNTKLSGSYEEISGSRPGDARPAGAP 1380
Query: 1381 GAAARVLTPGTPQCALPPAAPPGDEDDSEPVYIEMLGHAARPDSPDPGESVYEEMKCCLP 1440
GAAARVLTPGTPQCALPPAAPPGDEDDSEPVYIEMLGHAARPDSPDPGESVYEEMKCCLP
Sbjct: 1381 GAAARVLTPGTPQCALPPAAPPGDEDDSEPVYIEMLGHAARPDSPDPGESVYEEMKCCLP 1440
Query: 1441 DDGGPGAGSFLLHGASPPLLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPV 1500
DDGGPGAGSFLLHGASPPLLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPV
Sbjct: 1441 DDGGPGAGSFLLHGASPPLLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPV 1500
Query: 1501 TCSPASDESPLTPLEVKKLPVLETNLKYPVQPEGSSPLSPQYSKSQKGDGDRPASPGLAL 1560
TCSPASDESPLTPLEVKKLPVLETNLKYPVQPEGSSPLSPQYSKSQKGDGDRPASPGLAL
Sbjct: 1501 TCSPASDESPLTPLEVKKLPVLETNLKYPVQPEGSSPLSPQYSKSQKGDGDRPASPGLAL 1560
Query: 1561 FNGSGRASPPSTPPPPPPPPGPPPAPYRPCAHLAFPPEPAPVNAGKAGPSAEAPKVHPKP 1620
FNGSGRASPPSTPPPPPPPPGPPPAPYRPCAHLAFPPEPAPVNAGKAGPSAEAPKVHPKP
Sbjct: 1561 FNGSGRASPPSTPPPPPPPPGPPPAPYRPCAHLAFPPEPAPVNAGKAGPSAEAPKVHPKP 1620
Query: 1621 NSAPVAGPCSSFPKIPYSPVKATRADARKAGSSASPPAPYSPPSSRPLSSPLDELASLFN 1680
NSAPVAGPCSSFPKIPYSPVKATRADARKAGSSASPPAPYSPPSSRPLSSPLDELASLFN
Sbjct: 1621 NSAPVAGPCSSFPKIPYSPVKATRADARKAGSSASPPAPYSPPSSRPLSSPLDELASLFN 1680
Query: 1681 SGRSVLRKSAAGRKIREAEGFETNMNISSRDDPSTSEITSETQDRNANNHGIQLSNSLSS 1740
SGRSVLRKSAAGRKIREAEGFETNMNISSRDDPSTSEITSETQDRNANNHGIQLSNSLSS
Sbjct: 1681 SGRSVLRKSAAGRKIREAEGFETNMNISSRDDPSTSEITSETQDRNANNHGIQLSNSLSS 1740
Query: 1741 AITAENGNSISNGLPEEDGYSRLSISGTGTSTFQRHRDSHTTQVIHQLRLSENESVALQE 1800
AITAENGNSISNGLPEEDGYSRLSISGTGTSTFQRHRDSHTTQVIHQLRLSENESVALQE
Sbjct: 1741 AITAENGNSISNGLPEEDGYSRLSISGTGTSTFQRHRDSHTTQVIHQLRLSENESVALQE 1800
Query: 1801 LLDWRRKLCEEGQDWQQILHHAEPRVPPPPPCKKPSLLKKPEGASCNRLPSELWDTTI 1858
LLDWRRKLCEEGQDWQQILHHAEPRVPPPPPCKKPSLLKKPEGASCNRLPSELWDTTI
Sbjct: 1801 LLDWRRKLCEEGQDWQQILHHAEPRVPPPPPCKKPSLLKKPEGASCNRLPSELWDTTI 1858
>gi|134288915 myosin IIIB isoform 1 [Homo sapiens]
Length = 1314
Score = 443 bits (1139), Expect = e-124
Identities = 266/786 (33%), Positives = 439/786 (55%), Gaps = 41/786 (5%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
DDL L L++ ++++++QKR+ + IYT++GDIL+ +NP++ L IYS S+LY G
Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYH---G 402
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
+S PPH+F+ + A+ + + QC ++SGE GSGK+E++ I++HLT A+
Sbjct: 403 VKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQ 462
Query: 524 TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583
TL + V ++EAFG++ T +ND SS F KY E+ F + GARI YLLEKSR+
Sbjct: 463 TLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTP-TGVVMGARISEYLLEKSRV 521
Query: 584 VSQPLGQSNFLIFYLLMDGLSAEEKYG-LHLNNLCAHRYL-NQTIQDDASTGERSLNREK 641
+ Q + NF IFY + GL ++K L RY+ ++T + + R +
Sbjct: 522 IKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQ 581
Query: 642 LAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTAL---NEGNSAFVSDLQLLEQVA 698
++ ++GF+ EV +++ ILA IL++G+I F A+ ++ + + V + + L+ A
Sbjct: 582 FEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAA 641
Query: 699 GMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNS 758
+L +S +EL ALT+ +G+ IIR +T+ A RD ++K+LY RLFS++VN +N+
Sbjct: 642 SVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINT 701
Query: 759 CLHSQDEQKSM-QTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVE 817
L + S +++GILDIFGFE FQ+N FEQLC+N+ NE++ +Y N+ +F EQ+E
Sbjct: 702 LLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQME 761
Query: 818 CVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESS 877
EG+ N+ +LD F QKP G L LLDEES+ + + K + ++
Sbjct: 762 YQNEGIDAVPVEYEDNR-PLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFE---DNL 817
Query: 878 NTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTS 937
+ P K F I HYAG+V+YD G +EKN+D+L +++ V++TS
Sbjct: 818 RCKYFWRP----------KGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTS 867
Query: 938 ENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLK 997
EN+++ LF L++TG+L ++ + + K ++ ++++
Sbjct: 868 ENMLLQQLFSIPLTKTGNLAQT---------RARITVASSSLPPHFSAGKAKVDTLEVIR 918
Query: 998 KKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFY 1057
+T ++R T+AS R SLMD++ K+ PHF+ CI+PN+ + F
Sbjct: 919 HPEETTNMKR------QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRER 972
Query: 1058 VSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQ 1117
V AQL+ G+LE V I R GY R+ F +F+ RY LA F + ++ E C +L++
Sbjct: 973 VLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLA--FTAHQTPLASKESCVAILEK 1030
Query: 1118 CKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQE 1177
+L W +G KVFLKY+H +QLN L ++ +++ Q +G+L + + R++
Sbjct: 1031 SRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKG 1090
Query: 1178 VTSINS 1183
+I S
Sbjct: 1091 AIAIQS 1096
>gi|134288892 myosin IIIB isoform 2 [Homo sapiens]
Length = 1341
Score = 443 bits (1139), Expect = e-124
Identities = 266/786 (33%), Positives = 439/786 (55%), Gaps = 41/786 (5%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
DDL L L++ ++++++QKR+ + IYT++GDIL+ +NP++ L IYS S+LY G
Sbjct: 346 DDLVNLEVLDEDTIIHQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYH---G 402
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
+S PPH+F+ + A+ + + QC ++SGE GSGK+E++ I++HLT A+
Sbjct: 403 VKRASNPPHIFASADAAYQCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQ 462
Query: 524 TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583
TL + V ++EAFG++ T +ND SS F KY E+ F + GARI YLLEKSR+
Sbjct: 463 TLREKILQVNSLVEAFGNSCTAINDNSSRFGKYLEMMFTP-TGVVMGARISEYLLEKSRV 521
Query: 584 VSQPLGQSNFLIFYLLMDGLSAEEKYG-LHLNNLCAHRYL-NQTIQDDASTGERSLNREK 641
+ Q + NF IFY + GL ++K L RY+ ++T + + R +
Sbjct: 522 IKQAAREKNFHIFYYIYAGLHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQ 581
Query: 642 LAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTAL---NEGNSAFVSDLQLLEQVA 698
++ ++GF+ EV +++ ILA IL++G+I F A+ ++ + + V + + L+ A
Sbjct: 582 FEAIQHCFRIIGFTDKEVHSVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAA 641
Query: 699 GMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNS 758
+L +S +EL ALT+ +G+ IIR +T+ A RD ++K+LY RLFS++VN +N+
Sbjct: 642 SVLCISPEELQEALTSHCVVTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINT 701
Query: 759 CLHSQDEQKSM-QTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVE 817
L + S +++GILDIFGFE FQ+N FEQLC+N+ NE++ +Y N+ +F EQ+E
Sbjct: 702 LLQPDENICSAGGGMNVGILDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQME 761
Query: 818 CVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESS 877
EG+ N+ +LD F QKP G L LLDEES+ + + K + ++
Sbjct: 762 YQNEGIDAVPVEYEDNR-PLLDMFLQKPLGLLALLDEESRFPQATDQTLVDKFE---DNL 817
Query: 878 NTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTS 937
+ P K F I HYAG+V+YD G +EKN+D+L +++ V++TS
Sbjct: 818 RCKYFWRP----------KGVELCFGIQHYAGKVLYDASGVLEKNRDTLPADVVVVLRTS 867
Query: 938 ENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLK 997
EN+++ LF L++TG+L ++ + + K ++ ++++
Sbjct: 868 ENMLLQQLFSIPLTKTGNLAQT---------RARITVASSSLPPHFSAGKAKVDTLEVIR 918
Query: 998 KKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFY 1057
+T ++R T+AS R SLMD++ K+ PHF+ CI+PN+ + F
Sbjct: 919 HPEETTNMKR------QTVASYFRYSLMDLLSKMVVGQPHFVRCIKPNDDREALQFSRER 972
Query: 1058 VSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQ 1117
V AQL+ G+LE V I R GY R+ F +F+ RY LA F + ++ E C +L++
Sbjct: 973 VLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLA--FTAHQTPLASKESCVAILEK 1030
Query: 1118 CKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQE 1177
+L W +G KVFLKY+H +QLN L ++ +++ Q +G+L + + R++
Sbjct: 1031 SRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRYKKVREKREKG 1090
Query: 1178 VTSINS 1183
+I S
Sbjct: 1091 AIAIQS 1096
>gi|145275208 myosin IIIA [Homo sapiens]
Length = 1616
Score = 442 bits (1138), Expect = e-123
Identities = 300/937 (32%), Positives = 502/937 (53%), Gaps = 89/937 (9%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
DDLATL L++ ++ +++K + +QIY ++GDIL+ +NP++ L +YS+ S+LY S
Sbjct: 341 DDLATLEILDENTVSEQLEKCYSRDQIYVYVGDILIALNPFQSLGLYSTKHSKLYIGSKR 400
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
++ PPH+F+ + + + QC ++SGE G+GK+E + +++ LT A+
Sbjct: 401 ---TASPPHIFAMADLGYQSMITYNSDQCIVISGESGAGKTENAHLLVQQLTVLGKANNR 457
Query: 524 TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583
TL + V ++EAFG+A T +ND SS F KY E++F + GA+I YLLEKSR+
Sbjct: 458 TLQEKILQVNNLVEAFGNACTIINDNSSRFGKYLEMKFTS-SGAVVGAQISEYLLEKSRV 516
Query: 584 VSQPLGQSNFLIFYLLMDGLSAEEK---YGLHLNNLCAHRYLN----QTIQDDASTGERS 636
+ Q +G+ NF IFY + GL+ ++K Y L N RYL +T+QD + S
Sbjct: 517 IHQAIGEKNFHIFYYIYAGLAEKKKLAHYKLPENK--PPRYLQNDHLRTVQDIMN---NS 571
Query: 637 LNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTAL---NEGNSAFVSDLQL 693
+ + ++++ V+GF+ ++ +++ ILAAIL++G+I F+++ ++ + + +S+
Sbjct: 572 FYKSQYELIEQCFKVIGFTMEQLGSIYSILAAILNVGNIEFSSVATEHQIDKSHISNHTA 631
Query: 694 LEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLV 753
LE A +L + DEL ALT+ +G+ IIR +T++ A RD +AK+LY RLFS++V
Sbjct: 632 LENCASLLCIRADELQEALTSHCVVTRGETIIRPNTVEKATDVRDAMAKTLYGRLFSWIV 691
Query: 754 NTMNSCL-HSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFL 812
N +NS L H + L IGILDIFGFE F+KN FEQLC+N+ NE++ +Y N+ +F
Sbjct: 692 NCINSLLKHDSSPSGNGDELSIGILDIFGFENFKKNSFEQLCINIANEQIQYYYNQHVFA 751
Query: 813 HEQVECVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQS 872
EQ E + E V N +LD F QKP G L+LLDEES+ + + +K +
Sbjct: 752 WEQNEYLNEDVDARVIEYEDNW-PLLDMFLQKPMGLLSLLDEESRFPKATDQTLVEKFEG 810
Query: 873 LLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLF 932
L+S + P K +F I HYAG+V+Y+ G + KN+D+L +++
Sbjct: 811 NLKS---QYFWRP----------KRMELSFGIHHYAGKVLYNASGFLAKNRDTLPTDIVL 857
Query: 933 VMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLEL 992
++++S+N VI L L++TG+L P K K+ + + T+ +I K
Sbjct: 858 LLRSSDNSVIRQLVNHPLTKTGNL----PHSK---TKNVINYQMRTSEKLINLAKGDTGE 910
Query: 993 SKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDT 1052
+ ++ T+ Q T+AS R SLMD++ K+ PHF+ CI+PN+ +
Sbjct: 911 ATRHARETTNMKTQ--------TVASYFRYSLMDLLSKMVVGQPHFVRCIKPNSERQARK 962
Query: 1053 FDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCR 1112
+D V QL+Y G+LE +I R G+ R+ F++F+ RY L + ++ + + + C
Sbjct: 963 YDKEKVLLQLRYTGILETARIRRLGFSHRILFANFIKRYYLLC--YKSSEEPRMSPDTCA 1020
Query: 1113 LVLQQCKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIRGFL---------- 1162
+L++ L W +G KVFLKY+H +QLN + + K+I Q +R FL
Sbjct: 1021 TILEKAGLDNWALGKTKVFLKYYHVEQLNLMRKEAIDKLILIQACVRAFLCSRRYQKIQE 1080
Query: 1163 ------------ARQHLL--QRISIRQQEVTSINSFLQNTEDMGLK-----TYDALVIQN 1203
AR HL+ QR I + T++ + + ++ K T ++ V +
Sbjct: 1081 KRKESAIIIQSAARGHLVRKQRKEIVDMKNTAVTTIQTSDQEFDYKKNFENTRESFVKKQ 1140
Query: 1204 ASDIARENDRLRSEMNAPYHKEKLEVRNMQ----EEGSKRTDDKSGPRHFHPSSMSVCAA 1259
A + N+R ++AP +K + V EE + + + + P M+
Sbjct: 1141 AENAISANERF---ISAPNNKGSVSVVKTSTFKPEEETTNAVESNNRVYQTPKKMNNVYE 1197
Query: 1260 VDGLGQ-CLVGPSIWSPSLHSVFSMDDSSSLPSPRKQ 1295
+ + LVGP + SP SV ++++S+L K+
Sbjct: 1198 EEVKQEFYLVGPEV-SPKQKSVKDLEENSNLRKVEKE 1233
>gi|153792764 hypothetical protein LOC57624 [Homo sapiens]
Length = 653
Score = 357 bits (916), Expect = 6e-98
Identities = 252/595 (42%), Positives = 324/595 (54%), Gaps = 71/595 (11%)
Query: 1177 EVTSINSFLQNTEDMGLKTYDALVIQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEG 1236
E +++FLQ EDMG+K YD LVIQNASDIARENDRLR+E N Y KEK E R QEE
Sbjct: 12 EEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKEKNEKRRRQEEA 71
Query: 1237 SKRTDDKSGP--------RHFHPSSMSVCAAVDGLGQ-CLVGPSIWSPSLHSVFSMDDSS 1287
KR + G +HF M++ A D L C G S+ S SLHSV DD S
Sbjct: 72 IKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDS 131
Query: 1288 SLPSPRKQPPPKPKRDPNTRLSASYEAVS---ACLSAAREAANEALARPRPHSDDYSTMK 1344
S S R+QPPPKPKRDP+T+LS S E VS A S EA A+PRPHSD+YS K
Sbjct: 132 SCGS-RRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYS--K 188
Query: 1345 KIPPRKPKRSPNTKLSGSYEEISGSRPGDARPAGAPGAAARVLTPGTPQCALPPAAPPGD 1404
KIPP KPKR+PNT+LS S++E + G R + ++ + +P GD
Sbjct: 189 KIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQM-----------GSPAGD 237
Query: 1405 EDDSEPVYIEMLGHAARP---DSPDPGESVYEEMKCCLPDDGGPGAGSFLLHG------A 1455
++ EPVYIEM+G+ R + D E+VYEEMK + DD G A H A
Sbjct: 238 PEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCA 297
Query: 1456 SP--PLLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTP 1513
+P P L A P G CDIPPPFPNLL HRPPLLVFPP PV CSP SDESPLTP
Sbjct: 298 TPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTP 357
Query: 1514 LEVKKLPVLETNLKYPVQPEGSSPLS-----PQYSKSQKGDGDRPASPGLALFNGSGRAS 1568
LEV KLPVLE N+ Y QP G+SP + P ++K +K ++ A+ G
Sbjct: 358 LEVTKLPVLE-NVSYMKQPAGASPSTLPSHVPGHAKLEK---EQAAALG----------- 402
Query: 1569 PPSTPPPPPPPPGPPPAPYRPCAHLAFP----PEPAPVNAGKAGPSAEAPKVHPKPNSAP 1624
P S P P PP YR + +P P+PV+ G++ + P P A
Sbjct: 403 PASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR--PPPYDAV 460
Query: 1625 VAGPCS-SFPKIPYSPVKATRADARKAGSSASPPAPYSPPSSRPL--SSPLDELASLFNS 1681
+G S S P +P+S + D K ++A +P SR +SPL+EL SLF+S
Sbjct: 461 HSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSS 520
Query: 1682 GRSVLRKSAAGRKIRE-AEGFETNMNISSRDDPSTSEITSETQDRNANNHGIQLS 1735
GRS+LRKS++GR+ +E AE + + S ++E + ++ +HG S
Sbjct: 521 GRSLLRKSSSGRRSKEPAEKSTEELKVRSH----STEPLPKLDNKERGHHGASSS 571
>gi|239753409 PREDICTED: similar to hCG1811893 [Homo sapiens]
Length = 669
Score = 357 bits (916), Expect = 6e-98
Identities = 252/595 (42%), Positives = 324/595 (54%), Gaps = 71/595 (11%)
Query: 1177 EVTSINSFLQNTEDMGLKTYDALVIQNASDIARENDRLRSEMNAPYHKEKLEVRNMQEEG 1236
E +++FLQ EDMG+K YD LVIQNASDIARENDRLR+E N Y KEK E R QEE
Sbjct: 12 EEDPLDTFLQYIEDMGMKAYDGLVIQNASDIARENDRLRNETNLAYLKEKNEKRRRQEEA 71
Query: 1237 SKRTDDKSGP--------RHFHPSSMSVCAAVDGLGQ-CLVGPSIWSPSLHSVFSMDDSS 1287
KR + G +HF M++ A D L C G S+ S SLHSV DD S
Sbjct: 72 IKRIGGEVGRGHEGSYVGKHFRMGFMTMPAPQDRLPHPCSSGFSVRSQSLHSVGGTDDDS 131
Query: 1288 SLPSPRKQPPPKPKRDPNTRLSASYEAVS---ACLSAAREAANEALARPRPHSDDYSTMK 1344
S S R+QPPPKPKRDP+T+LS S E VS A S EA A+PRPHSD+YS K
Sbjct: 132 SCGS-RRQPPPKPKRDPSTKLSTSSETVSSTAASKSGKTPERTEASAKPRPHSDEYS--K 188
Query: 1345 KIPPRKPKRSPNTKLSGSYEEISGSRPGDARPAGAPGAAARVLTPGTPQCALPPAAPPGD 1404
KIPP KPKR+PNT+LS S++E + G R + ++ + +P GD
Sbjct: 189 KIPPPKPKRNPNTQLSTSFDETYIKKHGPRRTSLPRDSSLSQM-----------GSPAGD 237
Query: 1405 EDDSEPVYIEMLGHAARP---DSPDPGESVYEEMKCCLPDDGGPGAGSFLLHG------A 1455
++ EPVYIEM+G+ R + D E+VYEEMK + DD G A H A
Sbjct: 238 PEEEEPVYIEMVGNILRDFRKEDDDQSEAVYEEMKYPIFDDLGQDAKCDFDHHSCSSQCA 297
Query: 1456 SP--PLLHRAPEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTP 1513
+P P L A P G CDIPPPFPNLL HRPPLLVFPP PV CSP SDESPLTP
Sbjct: 298 TPTVPDLDFAKASVPCPPKGLLCDIPPPFPNLLSHRPPLLVFPPAPVHCSPNSDESPLTP 357
Query: 1514 LEVKKLPVLETNLKYPVQPEGSSPLS-----PQYSKSQKGDGDRPASPGLALFNGSGRAS 1568
LEV KLPVLE N+ Y QP G+SP + P ++K +K ++ A+ G
Sbjct: 358 LEVTKLPVLE-NVSYMKQPAGASPSTLPSHVPGHAKLEK---EQAAALG----------- 402
Query: 1569 PPSTPPPPPPPPGPPPAPYRPCAHLAFP----PEPAPVNAGKAGPSAEAPKVHPKPNSAP 1624
P S P P PP YR + +P P+PV+ G++ + P P A
Sbjct: 403 PASATPALSSSPPPPSTLYRTQSPHGYPKSHSTSPSPVSMGRSLTPLSLKR--PPPYDAV 460
Query: 1625 VAGPCS-SFPKIPYSPVKATRADARKAGSSASPPAPYSPPSSRPL--SSPLDELASLFNS 1681
+G S S P +P+S + D K ++A +P SR +SPL+EL SLF+S
Sbjct: 461 HSGSLSRSSPSVPHSTPRPVSQDGAKMVNAAVNTYGAAPGGSRSRTPTSPLEELTSLFSS 520
Query: 1682 GRSVLRKSAAGRKIRE-AEGFETNMNISSRDDPSTSEITSETQDRNANNHGIQLS 1735
GRS+LRKS++GR+ +E AE + + S ++E + ++ +HG S
Sbjct: 521 GRSLLRKSSSGRRSKEPAEKSTEELKVRSH----STEPLPKLDNKERGHHGASSS 571
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 357 bits (916), Expect = 6e-98
Identities = 276/868 (31%), Positives = 428/868 (49%), Gaps = 125/868 (14%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELP-IYSSMVSQLYFSSS 462
DD+A+L+EL+ GS++Y + +R+ NQIYT+IG IL VNPY+ + +Y + Y S
Sbjct: 66 DDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQY---S 122
Query: 463 GKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGAS- 521
+ LPPH+F+ + L++ QC ++SGE G+GK+E++K I++ L+ + S
Sbjct: 123 RRHLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSL 182
Query: 522 ------------RATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLT 569
RA L+S I+EAFG+AKT N+ SS F K+ +L C+ K +
Sbjct: 183 ELSLKEKTSCVERAILESS-----PIMEAFGNAKTVYNNNSSRFGKFVQLNICQ-KGNIQ 236
Query: 570 GARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQT-IQD 628
G RI YLLEK+R+V Q G+ N+ IFY L+ GL EE+ +L+ + YLNQ+ +
Sbjct: 237 GGRIVDYLLEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLSTPENYHYLNQSGCVE 296
Query: 629 DASTGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFV 688
D + ++ RE + A++V+ FS EV + +LA ILHLG+I F A V
Sbjct: 297 DKTISDQESFREVIT----AMDVMQFSKEEVREVSRLLAGILHLGNIEFIT---AGGAQV 349
Query: 689 SDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRL 748
S L + A +L + +L ALT + +G+ I+ +Q A RD LA +LY+
Sbjct: 350 SFKTALGRSAELLGLDPTQLTDALTQRSMFLRGEEILTPLNVQQAVDSRDSLAMALYACC 409
Query: 749 FSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINE 808
F +++ +NS + ++ KS IGILDIFGFE F+ N FEQ +N NEK+ Y N+
Sbjct: 410 FEWVIKKINSRIKGNEDFKS-----IGILDIFGFENFEVNHFEQFNINYANEKLQEYFNK 464
Query: 809 VLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPK 868
+F EQ+E +EG+ E NG +K G L L++EES + +S +
Sbjct: 465 HIFSLEQLEYSREGLVWEDI--DWIDNGECLDLIEKKLGLLALINEESHFPQATDSTLLE 522
Query: 869 KLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQ 928
KL S + +N + P VA+ + G + HYAG V YDV G +EKN+D+
Sbjct: 523 KLHS--QHANNHFYVKP------RVAVNNFG----VKHYAGEVQYDVRGILEKNRDTFRD 570
Query: 929 NLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKN 988
+LL +++ S I LF+ S+ N++
Sbjct: 571 DLLNLLRESRFDFIYDLFEHVSSR--------------------------------NNQD 598
Query: 989 YLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSK 1048
L+ ++ T++SQ + SL ++ L P F+ CI+PN K
Sbjct: 599 TLKCGSKHRRP---------------TVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQK 643
Query: 1049 LPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAA 1108
+PD FD V QL+Y G+LE V+I + GY VR F DF RYK L +
Sbjct: 644 MPDQFDQAVVLNQLRYSGMLETVRIRKAGYAVRRPFQDFYKRYKVLMRNL---ALPEDVR 700
Query: 1109 ERCRLVLQ--QCKLQGWQMGVRKVFLKYWHADQLNDLCLQLQRKIITCQKVIR----GFL 1162
+C +LQ WQ+G KVFL+ +L + + ++ VIR GFL
Sbjct: 701 GKCTSLLQLYDASNSEWQLGKTKVFLRESLEQKLEK---RREEEVSHAAMVIRAHVLGFL 757
Query: 1163 ARQH---LLQRISIRQQEVTSINSFLQNTEDMGLKTYDALVIQNASDIARENDRLRSEMN 1219
AR+ +L + I Q+ + +FL + LK A+V Q +LR ++
Sbjct: 758 ARKQYRKVLYCVVIIQK---NYRAFLLRRRFLHLKK-AAIVFQK---------QLRGQIA 804
Query: 1220 APYHKEKLEVRNMQEEGSKRTDDKSGPR 1247
+++ L + QEE K+ +++ R
Sbjct: 805 RRVYRQLLAEKREQEEKKKQEEEEKKKR 832
>gi|118402590 myosin XV [Homo sapiens]
Length = 3530
Score = 352 bits (903), Expect = 2e-96
Identities = 259/795 (32%), Positives = 398/795 (50%), Gaps = 101/795 (12%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
+D+ L +L + ++L ++ RF N IYT+IG IL+ VNPY+ IY Q Y +G
Sbjct: 1225 EDMTQLEDLQETTVLSNLKIRFERNLIYTYIGSILVSVNPYQMFGIYGPEQVQQY---NG 1281
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
+ PPHLF+ AF ++ ++ QC I+SGE GSGK+EA+K I+R+L
Sbjct: 1282 RALGENPPHLFAVANLAFAKMLDAKQNQCIIISGESGSGKTEATKLILRYLAAMNQKREV 1341
Query: 524 TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583
+ +LE+FG+AKT ND SS F K+ E+ F E ++GA YLLEKSR+
Sbjct: 1342 MQQIKILEATPLLESFGNAKTVRNDNSSRFGKFVEI-FLE-GGVISGAITSQYLLEKSRI 1399
Query: 584 VSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLA 643
V Q + N+ IFY L+ GL A+ + L + YLNQ + +S + +
Sbjct: 1400 VFQAKNERNYHIFYELLAGLPAQLRQAFSLQEAETYYYLNQ--GGNCEIAGKS-DADDFR 1456
Query: 644 VLKRALNVVGFSSLEVENLFVILAAILHLGDIRFT--ALNEGNSAFVSDLQLLEQVAGML 701
L A+ V+GFSS + +++F ILA+ILHLG++ F + A V + ++ VA +L
Sbjct: 1457 RLLAAMEVLGFSSEDQDSIFRILASILHLGNVYFEKYETDAQEVASVVSAREIQAVAELL 1516
Query: 702 QVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLH 761
Q+S + L A+T + + I T++ A RD +AK LY+ LFS+L+ +N+ +
Sbjct: 1517 QISPEGLQKAITFKVTETMREKIFTPLTVESAVDARDAIAKVLYALLFSWLITRVNALVS 1576
Query: 762 SQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQE 821
+ + TL I ILDI+GFE+ N FEQLC+N NE + + N+++F EQ E ++E
Sbjct: 1577 PRQD-----TLSIAILDIYGFEDLSFNSFEQLCINYANENLQYLFNKIVFQEEQEEYIRE 1631
Query: 822 GVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSNTNA 881
+ + NQ ++ KP G L +LD++ + + F LQ N
Sbjct: 1632 QIDWQEITFADNQ-PCINLISLKPYGILRILDDQCCFPQATDHTF---LQKCHYHHGANP 1687
Query: 882 VYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVV 941
+YS K + L + FTI HYAG+V Y V ++KN D + Q++L + S V
Sbjct: 1688 LYSKPK-----MPLPE----FTIKHYAGKVTYQVHKFLDKNHDQVRQDVLDLFVRSRTRV 1738
Query: 942 INHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGT 1001
+ HLF S Q ++ G
Sbjct: 1739 VAHLFSSHAPQAAP-----------------------------------------QRLGK 1757
Query: 1002 STFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQ 1061
S+ + RL + T+A++ ++SL+D++ K+++C P F+ C++PN+ K P F+ V AQ
Sbjct: 1758 SSSVTRLYKAH--TVAAKFQQSLLDLVEKMERCNPLFMRCLKPNHKKEPGLFEPDVVMAQ 1815
Query: 1062 LQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQ-CKL 1120
L+Y GVLE V+I + G+PVRL F F+ RY L + + + C VL + CK+
Sbjct: 1816 LRYSGVLETVRIRKEGFPVRLPFQGFIDRYCCLV---ALKHDLPANGDMCVSVLSRLCKV 1872
Query: 1121 QG--WQMGVRKVFLKYW----------HADQLNDLCLQ--------------LQRKIITC 1154
+++GV K+FLK H L L LQ L+ KII
Sbjct: 1873 MPNMYRVGVSKLFLKEHLYQLLESMREHVLNLAALTLQRCLRGFFIKRRFRSLRHKIILL 1932
Query: 1155 QKVIRGFLARQHLLQ 1169
Q RG+LARQ Q
Sbjct: 1933 QSRARGYLARQRYQQ 1947
Score = 48.9 bits (115), Expect = 5e-05
Identities = 100/388 (25%), Positives = 137/388 (35%), Gaps = 41/388 (10%)
Query: 1296 PPPKPKRDPNTRLSASYEAVSACLSAAREAANEALARPRPHSDDYSTMKKIPPRKPKRSP 1355
P P+P + R A++ A A+R A LA P+P + P P
Sbjct: 739 PGPRPSFRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLAPPSPQ 798
Query: 1356 NTKLSGSYEE---ISGSRPGDARPAGAP-GAAARVLTPGTPQCALP-PAAPP----GDED 1406
+ +G ++ RP + + AP AA R+ PG+P P P +PP
Sbjct: 799 LSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCHSPR 858
Query: 1407 DSEPVYIEMLGHAARPDSPDPGESVYEEMKCCLPDDGGPGAGSF---LLHGASPPLLHRA 1463
S L H R S P +V +++ LP P AG++ L H SP R
Sbjct: 859 RSSLNLPSRLPHTWRRLSEPPTRAVKPQVR--LPFHRPPRAGAWRAPLEHRESP----RE 912
Query: 1464 PEDEAAGPPGDACDIPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTPLEVKKLPVLE 1523
PED +PP P+ PP PP+P S P V + P L+
Sbjct: 913 PEDSET-----PWTVPPLAPSWDVDMPP-TQRPPSPWPGGAGSRRGFSRPPPVPENPFLQ 966
Query: 1524 TNLKYPVQPEGSSPLSPQYSKSQKGDGDRPASPGLALFNGSGRASPPSTPPPPPPPPGPP 1583
L PV P P ++ G R PG S A P P G P
Sbjct: 967 --LLGPVPSPTLQPEDPAADMTRVFLG-RHHEPGPGQLTKS--AGPTPEKPEEEATLGDP 1021
Query: 1584 PAPYRPCAHLAFPPEPAPVNAGKAGPSAEAPK-VHPKPNSAPVAGPCSSFPKIPYSPVKA 1642
P PP PAP PK V P+ + P S+P +A
Sbjct: 1022 QLPAE-----TKPPTPAPPKDVTPPKDITPPKDVLPEQKT---LRPSLSYPLAACDQTRA 1073
Query: 1643 TRADARKAGS---SASPPAPYSPPSSRP 1667
T + G+ +A+P AP P P
Sbjct: 1074 TWPPWHRWGTLPQAAAPLAPIRAPEPLP 1101
Score = 46.6 bits (109), Expect = 2e-04
Identities = 77/283 (27%), Positives = 95/283 (33%), Gaps = 56/283 (19%)
Query: 1420 ARPDSPDPGESVYEEM--KCCLPDDGGPGAGSFLLHGASPPLLHRAPEDEAAGPPGDACD 1477
AR P E+ Y+ K D PG +L A P ++A PP
Sbjct: 595 ARAGGPAVREAAYKRFGYKLAGMDPEKPGT-PIVLRRAQP---RARSSNDARRPPA---- 646
Query: 1478 IPPPFPNLLPHRPPLLVFPPTPVTCSPASDESPLTPLEVKKLPVLETNLKYPVQPEGSSP 1537
P P P L H LL PP P P+S P PL P L + L P P GS
Sbjct: 647 -PQPAPRTLSHWSALLS-PPVPPR-PPSSGPPPAPPLS----PAL-SGLPRPASPYGSLR 698
Query: 1538 LSPQYSKSQKGDGDRPASPGLALFNGSGRASPPSTPPPPPPP----PGPPPA---PYRPC 1590
P + P + A PP+ P PP PGP P+ R
Sbjct: 699 RHPPPWAAPAHVPPAPQASWWAF------VEPPAVSPEVPPDLLAFPGPRPSFRGSRRRG 752
Query: 1591 AHLAFPPEPAPVNAGKAGPSAEAPKVHPKPNSAPVAGPCSSFPKIPYSPVKATRADA--- 1647
A FP + +A +P+ P S+P G CS P P SP + R
Sbjct: 753 AAFGFPGASPRASRRRAWSPLASPQ--PSLRSSPGLGYCS--PLAPPSPQLSLRTGPFQP 808
Query: 1648 ------------------RKAGSSASPPAPYSPPSSRPLSSPL 1672
R+A PP P S RP S PL
Sbjct: 809 PFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPL 851
Score = 45.1 bits (105), Expect = 7e-04
Identities = 48/149 (32%), Positives = 61/149 (40%), Gaps = 26/149 (17%)
Query: 1549 DGDRPASPGLA---LFNGSGRASPPSTPPPPPPPPGPPPAPYRPCAHLAFPPEPAPVNAG 1605
D RP +P A L + S SPP PP PP GPPPAP A P +P +
Sbjct: 640 DARRPPAPQPAPRTLSHWSALLSPPV--PPRPPSSGPPPAPPLSPALSGLPRPASPYGSL 697
Query: 1606 KAGPSAEAPKVHPKPNSAPVAG------PCSSFPKIP------YSPVKATRADARKAGSS 1653
+ P A H P AP A P + P++P P + R R+ +
Sbjct: 698 RRHPPPWAAPAHVPP--APQASWWAFVEPPAVSPEVPPDLLAFPGPRPSFRGSRRRGAAF 755
Query: 1654 ASPPAPYSPPSSR-----PLSSPLDELAS 1677
P A SP +SR PL+SP L S
Sbjct: 756 GFPGA--SPRASRRRAWSPLASPQPSLRS 782
Score = 33.5 bits (75), Expect = 2.0
Identities = 56/228 (24%), Positives = 72/228 (31%), Gaps = 34/228 (14%)
Query: 1373 DARPAGAPGAAARVLTPGTPQCALP-PAAPPGDEDDSEPVYIEMLGHAARPDSPDPGESV 1431
DAR AP A R L+ + + P P PP P L RP SP
Sbjct: 640 DARRPPAPQPAPRTLSHWSALLSPPVPPRPPSSGPPPAPPLSPALSGLPRPASP------ 693
Query: 1432 YEEMKCCLPDDGGPGAGSFLLHGASPPLLHRAPEDEAAGPPGDACDIPPP---FPNLLP- 1487
Y ++ P P A P +A PP + ++PP FP P
Sbjct: 694 YGSLRRHPPPWAAP---------AHVPPAPQASWWAFVEPPAVSPEVPPDLLAFPGPRPS 744
Query: 1488 -----HRPPLLVFPPTPVTCSPASDESPLTPLEVKKLPVLETNLKYPVQPEG------SS 1536
R FP S SPL + P+ P +
Sbjct: 745 FRGSRRRGAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLAPPSPQLSLRTG 804
Query: 1537 PLSPQYSKSQKGDGDRPASPGLALFNGSGRASPPSTP-PPPPPPPGPP 1583
P P + + SP A +GR PP +P P P PP PP
Sbjct: 805 PFQPPFLPPARRPRSLQESP--APRRAAGRLGPPGSPLPGSPRPPSPP 850
Score = 33.1 bits (74), Expect = 2.6
Identities = 36/140 (25%), Positives = 58/140 (41%), Gaps = 24/140 (17%)
Query: 1503 SPASDESPLTPLEVKKLPVLETN---LKYPVQPEGSSPLSPQYSKSQKGDGDRPASPGLA 1559
S ++++P P E K +P L+ + L+ + + L+ + + +P S L
Sbjct: 2427 SSGTEDTPRRPPEPKPIPGLDASTLALQQAFIHKQAVLLAREMTLQATALQQQPLSAAL- 2485
Query: 1560 LFNGSGRASPPSTPPPPPPPP-----GPPPAPYRPCAHLAFPPEPAPVNAGKAGPSAEAP 1614
R+ P PP P P GPP +P A P AP P A+AP
Sbjct: 2486 ------RSLPAEKPPAPEAQPTSVGTGPPA---KPVLLRATPKPLAPA------PLAKAP 2530
Query: 1615 KVHPKPNSAPVAGPCSSFPK 1634
++ KP +APV + P+
Sbjct: 2531 RLPIKPVAAPVLAQDQASPE 2550
Score = 31.2 bits (69), Expect = 9.8
Identities = 28/104 (26%), Positives = 42/104 (40%), Gaps = 14/104 (13%)
Query: 1597 PEPAPVNAGKAGPSAEAPKVHPKPNSAPVAGPCSSFPKIPYSPVKATRADARKAGSSASP 1656
PE P + G GP A+ + P A P + P++P PV A +A +
Sbjct: 2496 PEAQPTSVG-TGPPAKPVLLRATPKPLAPA-PLAKAPRLPIKPVAAPVLAQDQASPETTS 2553
Query: 1657 PAP----YSPPSSRPLSSPLDELASL-------FNSGR-SVLRK 1688
P+P YS +S P ++ ++ F GR LRK
Sbjct: 2554 PSPELVRYSTLNSEHFPQPTQQIKNIVRQYQQPFRGGRPEALRK 2597
>gi|122937512 myosin VIIB [Homo sapiens]
Length = 2116
Score = 352 bits (903), Expect = 2e-96
Identities = 246/787 (31%), Positives = 393/787 (49%), Gaps = 69/787 (8%)
Query: 397 LMPPAPN-----DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYS 451
L P PN DD+ L +LN+ +++ + R+ ++IYT+ G IL+ VNP++ LP+Y+
Sbjct: 56 LSPMHPNSVQGVDDMIRLGDLNEAGMVHNLLIRYQQHKIYTYTGSILVAVNPFQVLPLYT 115
Query: 452 SMVSQLYFSSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQII 511
QLY+S + LPPH+F+ + + R +R QC I+SGE G+GK+E +K I+
Sbjct: 116 LEQVQLYYS---RHMGELPPHVFAIANNCYFSMKRNKRDQCCIISGESGAGKTETTKLIL 172
Query: 512 RHLTCRAGASRATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGA 571
+ L +G + ++ + ILEAFG+AKT ND SS F KY ++ F + GA
Sbjct: 173 QFLATISG-QHSWIEQQVLEANPILEAFGNAKTIRNDNSSRFGKYIDIYF-NPSGVIEGA 230
Query: 572 RIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDAS 631
RI +LLEKSR+ Q + N+ IFY ++ G+SAE+K L L + YL + +
Sbjct: 231 RIEQFLLEKSRVCRQAPEERNYHIFYCMLMGVSAEDKQLLSLGTPSEYHYLTM---GNCT 287
Query: 632 TGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTA--LNEGNSAFVS 689
+ E + + A ++ A+ ++ FS E ++ +LAAILHLG++ F A +++ V
Sbjct: 288 SCEGLNDAKDYAHIRSAMKILQFSDSESWDVIKLLAAILHLGNVGFMASVFENLDASDVM 347
Query: 690 DLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLF 749
+ V +L+V EL L +G+ + R I A RD K +Y LF
Sbjct: 348 ETPAFPTVMKLLEVQHQELRDCLIKHTILIRGEFVTRSLNIAQAADRRDAFVKGIYGHLF 407
Query: 750 SFLVNTMNSCLHSQDEQKSMQTLD-IGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINE 808
++V +N+ + + Q IG+LDIFGFE F+ N FEQLC+N NE + + +
Sbjct: 408 LWIVKKINAAIFTPPAQDPKNVRRAIGLLDIFGFENFENNSFEQLCINFANEHLQQFFVQ 467
Query: 809 VLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPK 868
+F EQ E E ++ + + N+ LD KP ++LLDEES+ + +
Sbjct: 468 HVFTMEQEEYRSENISWDYIHYTDNR-PTLDLLALKPMSIISLLDEESRFPQGTDLTMLQ 526
Query: 869 KLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQ 928
KL S+ +N A P N+ H F I H+AG V Y G +EKN+D LS
Sbjct: 527 KLNSV--HANNKAFLQPK-----NI----HDARFGIAHFAGEVYYQAEGFLEKNRDVLST 575
Query: 929 NLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKN 988
++L ++ +S+N + +F +L++T GH + +
Sbjct: 576 DILTLVYSSKNKFLREIFNLELAETK-----------LGHGTIRQA-------------- 610
Query: 989 YLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSK 1048
K G F P T+ SQ ++SL ++ L C P+FI CI+PN K
Sbjct: 611 ---------KAGNHLFKSADSNKRPSTLGSQFKQSLDQLMKILTNCQPYFIRCIKPNEYK 661
Query: 1049 LPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAA 1108
P FD QL+Y G++E V I + G+P+R +F +F R+ L +R + Q
Sbjct: 662 KPLLFDRELCLRQLRYSGMMETVHIRKSGFPIRYTFEEFSQRFGVLLPNAMR-MQLQGKL 720
Query: 1109 ERCRLVLQQCKL---QGWQMGVRKVFLKYWHADQLNDL--CLQLQRKIITCQKVIRGFLA 1163
+ L + L + W+ G K+FL+ H D L ++ L R ++ QKV+RG+
Sbjct: 721 RQMTLGITDVWLRTDKDWKAGKTKIFLRD-HQDTLLEVQRSQVLDRAALSIQKVLRGYRY 779
Query: 1164 RQHLLQR 1170
R+ L++
Sbjct: 780 RKEFLRQ 786
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 352 bits (902), Expect = 3e-96
Identities = 244/779 (31%), Positives = 391/779 (50%), Gaps = 93/779 (11%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
+D+ L +LN+ +L + R+ ++ IYT+ G IL+ VNPY+ L IYS + Y +
Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQY---TN 124
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
K +PPH+F+ + + + R R QC I+SGE G+GK+E++K I++ L +G +
Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG-QHS 183
Query: 524 TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583
++ + ILEAFG+AKT ND SS F KY ++ F ++ + GA+I YLLEKSR+
Sbjct: 184 WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHF-NKRGAIEGAKIEQYLLEKSRV 242
Query: 584 VSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLA 643
Q L + N+ +FY +++G+S ++K L L + YL + T E ++ ++ A
Sbjct: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYL---AMGNCITCEGRVDSQEYA 299
Query: 644 VLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGN--SAFVSDLQLLEQVAGML 701
++ A+ V+ F+ E + +LAAILHLG++++ A N + V L A +L
Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLL 359
Query: 702 QVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLH 761
+V+ +L S LT+ +G+ + + + A RD K +Y RLF ++V+ +N+ ++
Sbjct: 360 EVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIY 419
Query: 762 ---SQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVEC 818
SQD + S ++ IG+LDIFGFE F N FEQLC+N NE + + +F EQ E
Sbjct: 420 KPPSQDVKNSRRS--IGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEY 477
Query: 819 VQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSN 878
E + NQ+ LD KP ++L+DEES+ ++ KL S
Sbjct: 478 DLESIDWLHIEFTDNQD-ALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNS---QHK 533
Query: 879 TNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSE 938
NA Y P K+ +H T F I H+AG V Y+ G +EKN+D+L +++ ++ +S
Sbjct: 534 LNANYIPPKN--------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSR 585
Query: 939 NVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKK 998
N I +FQ+ ++ P+
Sbjct: 586 NKFIKQIFQADVAMGAETRKRSPTL----------------------------------- 610
Query: 999 KGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYV 1058
+S F + LE LM +G C P F+ CI+PN K P FD
Sbjct: 611 --SSQFKRSLE-------------LLMRTLG---ACQPFFVRCIKPNEFKKPMLFDRHLC 652
Query: 1059 SAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQC 1118
QL+Y G++E ++I R GYP+R SF +F+ RY+ L K+ C+ + +
Sbjct: 653 VRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAV 712
Query: 1119 --KLQGWQMGVRKVFLKYWHADQLNDLCLQLQR------KIITCQKVIRGFLARQHLLQ 1169
WQ+G K+FLK H D+ L+++R ++I QKVIRGF R + L+
Sbjct: 713 LGTHDDWQIGKTKIFLKDHH-----DMLLEVERDKAITDRVILLQKVIRGFKDRSNFLK 766
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 352 bits (902), Expect = 3e-96
Identities = 244/779 (31%), Positives = 391/779 (50%), Gaps = 93/779 (11%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
+D+ L +LN+ +L + R+ ++ IYT+ G IL+ VNPY+ L IYS + Y +
Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQY---TN 124
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
K +PPH+F+ + + + R R QC I+SGE G+GK+E++K I++ L +G +
Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG-QHS 183
Query: 524 TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583
++ + ILEAFG+AKT ND SS F KY ++ F ++ + GA+I YLLEKSR+
Sbjct: 184 WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHF-NKRGAIEGAKIEQYLLEKSRV 242
Query: 584 VSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLA 643
Q L + N+ +FY +++G+S ++K L L + YL + T E ++ ++ A
Sbjct: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYL---AMGNCITCEGRVDSQEYA 299
Query: 644 VLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGN--SAFVSDLQLLEQVAGML 701
++ A+ V+ F+ E + +LAAILHLG++++ A N + V L A +L
Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLL 359
Query: 702 QVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLH 761
+V+ +L S LT+ +G+ + + + A RD K +Y RLF ++V+ +N+ ++
Sbjct: 360 EVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIY 419
Query: 762 ---SQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVEC 818
SQD + S ++ IG+LDIFGFE F N FEQLC+N NE + + +F EQ E
Sbjct: 420 KPPSQDVKNSRRS--IGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEY 477
Query: 819 VQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSN 878
E + NQ+ LD KP ++L+DEES+ ++ KL S
Sbjct: 478 DLESIDWLHIEFTDNQD-ALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNS---QHK 533
Query: 879 TNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSE 938
NA Y P K+ +H T F I H+AG V Y+ G +EKN+D+L +++ ++ +S
Sbjct: 534 LNANYIPPKN--------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSR 585
Query: 939 NVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKK 998
N I +FQ+ ++ P+
Sbjct: 586 NKFIKQIFQADVAMGAETRKRSPTL----------------------------------- 610
Query: 999 KGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYV 1058
+S F + LE LM +G C P F+ CI+PN K P FD
Sbjct: 611 --SSQFKRSLE-------------LLMRTLG---ACQPFFVRCIKPNEFKKPMLFDRHLC 652
Query: 1059 SAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQC 1118
QL+Y G++E ++I R GYP+R SF +F+ RY+ L K+ C+ + +
Sbjct: 653 VRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAV 712
Query: 1119 --KLQGWQMGVRKVFLKYWHADQLNDLCLQLQR------KIITCQKVIRGFLARQHLLQ 1169
WQ+G K+FLK H D+ L+++R ++I QKVIRGF R + L+
Sbjct: 713 LGTHDDWQIGKTKIFLKDHH-----DMLLEVERDKAITDRVILLQKVIRGFKDRSNFLK 766
>gi|189083798 myosin VIIA isoform 1 [Homo sapiens]
Length = 2215
Score = 352 bits (902), Expect = 3e-96
Identities = 244/779 (31%), Positives = 391/779 (50%), Gaps = 93/779 (11%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
+D+ L +LN+ +L + R+ ++ IYT+ G IL+ VNPY+ L IYS + Y +
Sbjct: 68 EDMIRLGDLNEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQY---TN 124
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
K +PPH+F+ + + + R R QC I+SGE G+GK+E++K I++ L +G +
Sbjct: 125 KKIGEMPPHIFAIADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFLAAISG-QHS 183
Query: 524 TLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRL 583
++ + ILEAFG+AKT ND SS F KY ++ F ++ + GA+I YLLEKSR+
Sbjct: 184 WIEQQVLEATPILEAFGNAKTIRNDNSSRFGKYIDIHF-NKRGAIEGAKIEQYLLEKSRV 242
Query: 584 VSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREKLA 643
Q L + N+ +FY +++G+S ++K L L + YL + T E ++ ++ A
Sbjct: 243 CRQALDERNYHVFYCMLEGMSEDQKKKLGLGQASDYNYL---AMGNCITCEGRVDSQEYA 299
Query: 644 VLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGN--SAFVSDLQLLEQVAGML 701
++ A+ V+ F+ E + +LAAILHLG++++ A N + V L A +L
Sbjct: 300 NIRSAMKVLMFTDTENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPSLATAASLL 359
Query: 702 QVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLH 761
+V+ +L S LT+ +G+ + + + A RD K +Y RLF ++V+ +N+ ++
Sbjct: 360 EVNPPDLMSCLTSRTLITRGETVSTPLSREQALDVRDAFVKGIYGRLFVWIVDKINAAIY 419
Query: 762 ---SQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVEC 818
SQD + S ++ IG+LDIFGFE F N FEQLC+N NE + + +F EQ E
Sbjct: 420 KPPSQDVKNSRRS--IGLLDIFGFENFAVNSFEQLCINFANEHLQQFFVRHVFKLEQEEY 477
Query: 819 VQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESSN 878
E + NQ+ LD KP ++L+DEES+ ++ KL S
Sbjct: 478 DLESIDWLHIEFTDNQD-ALDMIANKPMNIISLIDEESKFPKGTDTTMLHKLNS---QHK 533
Query: 879 TNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSE 938
NA Y P K+ +H T F I H+AG V Y+ G +EKN+D+L +++ ++ +S
Sbjct: 534 LNANYIPPKN--------NHETQFGINHFAGIVYYETQGFLEKNRDTLHGDIIQLVHSSR 585
Query: 939 NVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKK 998
N I +FQ+ ++ P+
Sbjct: 586 NKFIKQIFQADVAMGAETRKRSPTL----------------------------------- 610
Query: 999 KGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYV 1058
+S F + LE LM +G C P F+ CI+PN K P FD
Sbjct: 611 --SSQFKRSLE-------------LLMRTLG---ACQPFFVRCIKPNEFKKPMLFDRHLC 652
Query: 1059 SAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQQC 1118
QL+Y G++E ++I R GYP+R SF +F+ RY+ L K+ C+ + +
Sbjct: 653 VRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYRVLLPGVKPAYKQGDLRGTCQRMAEAV 712
Query: 1119 --KLQGWQMGVRKVFLKYWHADQLNDLCLQLQR------KIITCQKVIRGFLARQHLLQ 1169
WQ+G K+FLK H D+ L+++R ++I QKVIRGF R + L+
Sbjct: 713 LGTHDDWQIGKTKIFLKDHH-----DMLLEVERDKAITDRVILLQKVIRGFKDRSNFLK 766
>gi|27544941 myosin IF [Homo sapiens]
Length = 1098
Score = 332 bits (852), Expect = 2e-90
Identities = 238/744 (31%), Positives = 371/744 (49%), Gaps = 100/744 (13%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
DD+ L ++ + ++ ++KRF ++ I+T+IG +L+ VNP+K++P ++ LY G
Sbjct: 20 DDMVLLPQITEDAIAANLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLY---QG 76
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
PPH+++ + + + + QC I+SGE G+GK+ A+K I+ +++ +G
Sbjct: 77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGEK 136
Query: 524 TLDSRFKHVVC----ILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLE 579
K ++ +LEAFG+AKT N+ SS F KYFE+QF R + G +I +LLE
Sbjct: 137 V--QHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQF-SRGGEPDGGKISNFLLE 193
Query: 580 KSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQ--TIQDDASTGERSL 637
KSR+V Q + NF I+Y L++G S E++ L L + YLNQ T Q D T +RS
Sbjct: 194 KSRVVMQNENERNFHIYYQLLEGASQEQRQNLGLMTPDYYYYLNQSDTYQVDG-TDDRSD 252
Query: 638 NREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQV 697
E L+ A+ V+G + + ++A ILHLG+I F +GN A V + LL
Sbjct: 253 FGETLS----AMQVIGIPPSIQQLVLQLVAGILHLGNISFC--EDGNYARVESVDLLAFP 306
Query: 698 AGMLQVSTDELASALTT---DIQYF-KGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLV 753
A +L + + L LT+ D ++ + + I ++ A + RD LAK LY+RLF FLV
Sbjct: 307 AYLLGIDSGRLQEKLTSRKMDSRWGGRSESINVTLNVEQAAYTRDALAKGLYARLFDFLV 366
Query: 754 NTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLH 813
+N + QK + IG+LDI+GFE FQKN FEQ C+N NEK+ E+
Sbjct: 367 EAINRAM-----QKPQEEYSIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLKA 421
Query: 814 EQVECVQEGVTMETAYSPGNQNGVLDFFFQK--PSGFLTLLDEESQMIWSVESNFPKK-L 870
EQ E VQEG+ T N V D K P G +++LD+ + + + L
Sbjct: 422 EQEEYVQEGIRW-TPIQYFNNKVVCDLIENKLSPPGIMSVLDDVCATMHATGGGADQTLL 480
Query: 871 QSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNL 930
Q L + T+ ++ G F I HYAG+V YDV G E+N+D L +L
Sbjct: 481 QKLQAAVGTHEHFNSWSAG------------FVIHHYAGKVSYDVSGFCERNRDVLFSDL 528
Query: 931 LFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYL 990
+ +M+TSE + LF KL G+ K
Sbjct: 529 IELMQTSEQAFLRMLFPEKLD--------------------------------GDKK--- 553
Query: 991 ELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLP 1050
G P T S+++K D++ L +CTPH+I CI+PN +K P
Sbjct: 554 --------------------GRPSTAGSKIKKQANDLVATLMRCTPHYIRCIKPNETKRP 593
Query: 1051 DTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLA-DTFLREKKEQSAAE 1109
++ V Q++Y+G+ E +++ R G+ R F+ FL RY L +T+ R + ++
Sbjct: 594 RDWEENRVKHQVEYLGLKENIRVRRAGFAYRRQFAKFLQRYAILTPETWPRWRGDERQGV 653
Query: 1110 RCRLVLQQCKLQGWQMGVRKVFLK 1133
+ L + +QMG KVF+K
Sbjct: 654 QHLLRAVNMEPDQYQMGSTKVFVK 677
>gi|51100974 myosin ID [Homo sapiens]
Length = 1006
Score = 331 bits (849), Expect = 4e-90
Identities = 231/771 (29%), Positives = 391/771 (50%), Gaps = 79/771 (10%)
Query: 405 DLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGK 464
D + ++ + ++ RF +IYTFIG++++ VNPYK L IY + Y G+
Sbjct: 13 DFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQY---KGR 69
Query: 465 LCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRAT 524
PPHLF+ + A+ + R + C ++SGE G+GK+EASK I++++ S+
Sbjct: 70 ELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRA 129
Query: 525 LDSRFKHVV----CILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEK 580
R K+++ C+LEAFG+AKT ND SS F KY ++ F + K G I YLLEK
Sbjct: 130 EVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINF-DFKGDPIGGHINNYLLEK 188
Query: 581 SRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLN-NLCAHRYLNQTIQDDASTGERSLNR 639
SR++ Q G+ +F FY L+ G S + LHL +L ++ Y++ Q +S + +
Sbjct: 189 SRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAA--- 245
Query: 640 EKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAG 699
+ V+ A+ V+GF E++ ++ ILAAILHLG+++F +G++ + + +++ +A
Sbjct: 246 -EFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVV--DGDTPLIENGKVVSIIAE 302
Query: 700 MLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSC 759
+L TD + AL D+I ++HT Q A + RD AK++Y RLF ++V +N
Sbjct: 303 LLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDI 362
Query: 760 LHSQDEQKSMQTLD--IGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVE 817
+ ++ ++ + IG+LDI+GFE F N FEQ C+N NEK+ +++ EQ E
Sbjct: 363 IEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEE 422
Query: 818 CVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIWSVESNFPKKLQSLLESS 877
+EG+ + NQ ++D Q+ G + +LD+ + V L++L
Sbjct: 423 YQREGIPWKHIDYFNNQI-IVDLVEQQHKGIIAILDDACMNVGKVTDEM--FLEALNSKL 479
Query: 878 NTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTS 937
+A +S K + L + F I HYAG V+Y V+G I+KNKD+L Q+ +M S
Sbjct: 480 GKHAHFSSRKLCASDKIL-EFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNS 538
Query: 938 ENVVINHLF-QSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLL 996
N V+ +++ + KLS T + + +TA+++
Sbjct: 539 SNPVLKNMWPEGKLSIT-----------------EVTKRPLTAATL-------------- 567
Query: 997 KKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNF 1056
+ S++ ++ L P+++ CI+PN+ K P FD+
Sbjct: 568 -----------------------FKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDE 604
Query: 1057 YVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCRLVLQ 1116
Q++Y+G+LE V++ R G+ R ++ FL RYK +++ S E + +++
Sbjct: 605 RCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIE 664
Query: 1117 QCKLQ-GWQMGVRKVFLKYWHA-DQLNDLCLQ-LQRKIITCQKVIRGFLAR 1164
+C Q G K+F++ L +L Q L R ++ QKV RG LAR
Sbjct: 665 RCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLAR 715
>gi|124494247 myosin IC isoform b [Homo sapiens]
Length = 1044
Score = 329 bits (844), Expect = 1e-89
Identities = 238/766 (31%), Positives = 386/766 (50%), Gaps = 77/766 (10%)
Query: 413 NDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPH 472
++ + + +++RF N IYT+IG +L+ VNPY++L IYS + Y G +PPH
Sbjct: 40 SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERY---RGVSFYEVPPH 96
Query: 473 LFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHL--TCRAGASRATLDSRFK 530
LF+ + + L E+R Q ++SGE G+GK+EA+K++++ TC A + R
Sbjct: 97 LFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLL 156
Query: 531 HVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQ 590
+LEAFG+AKT ND SS F KY ++QF + K G I +YLLEKSR+V Q G+
Sbjct: 157 QSNPVLEAFGNAKTLRNDNSSRFGKYMDVQF-DFKGAPVGGHILSYLLEKSRVVHQNHGE 215
Query: 591 SNFLIFYLLMDGLSAEEKYGLHLN-NLCAHRYLNQTIQDDASTGERSLNREKLAVLKRAL 649
NF IFY L++G E L L N ++ YL ++ + ++ V+++AL
Sbjct: 216 RNFHIFYQLLEGGEEETLRRLGLERNPQSYLYL---VKGQCAKVSSINDKSDWKVVRKAL 272
Query: 650 NVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELA 709
V+ F+ EVE+L I+A++LHLG+I F A E N+ ++ QL + + +L V L
Sbjct: 273 TVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL-KYLTRLLSVEGSTLR 331
Query: 710 SALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSM 769
ALT KG+ ++ ++ A + RD LAK++YSR F++LV +N L S+D +
Sbjct: 332 EALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPS 391
Query: 770 --QTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMET 827
T +G+LDI+GFE FQ N FEQ C+N NEK+ E+ EQ E EG+ E
Sbjct: 392 WRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEP 451
Query: 828 AYSPGNQNGVLDFFFQKPSGFLTLLDEES-QMIWSVESNFPKKLQSLLESSNTNAVYSPM 886
N+ + D +K G +++LDEE + + + F +KL+ ++ + + + +
Sbjct: 452 VQYFNNKI-ICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVK-HHPHFLTHKL 509
Query: 887 KDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLF 946
D +L F ++HYAG V Y V G ++KN D L +NL M +S+N +++ F
Sbjct: 510 ADQRTRKSL--GRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCF 567
Query: 947 QSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQ 1006
+S L KK
Sbjct: 568 D---------------------RSELSDKKR----------------------------- 577
Query: 1007 RLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIG 1066
P T+A+Q + SL+ ++ LQ P ++ CI+PN++K P FD + Q++Y+G
Sbjct: 578 ------PETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLG 631
Query: 1067 VLEMVKIFRYGYPVRLSFSDFLSRYKPLA-DTFLREKKEQSAAERCRLVLQQCKLQGWQM 1125
+LE +++ R G+ R + FL RYK L +T+ + K + ++M
Sbjct: 632 LLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKM 691
Query: 1126 GVRKVFLKYWHADQLNDLCLQLQRKIIT--CQKVIRGFLARQHLLQ 1169
G K+F+++ + L+++R+ + Q RGF RQ L+
Sbjct: 692 GRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLR 737
>gi|124494238 myosin IC isoform a [Homo sapiens]
Length = 1063
Score = 329 bits (844), Expect = 1e-89
Identities = 238/766 (31%), Positives = 386/766 (50%), Gaps = 77/766 (10%)
Query: 413 NDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPH 472
++ + + +++RF N IYT+IG +L+ VNPY++L IYS + Y G +PPH
Sbjct: 59 SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERY---RGVSFYEVPPH 115
Query: 473 LFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHL--TCRAGASRATLDSRFK 530
LF+ + + L E+R Q ++SGE G+GK+EA+K++++ TC A + R
Sbjct: 116 LFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLL 175
Query: 531 HVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQ 590
+LEAFG+AKT ND SS F KY ++QF + K G I +YLLEKSR+V Q G+
Sbjct: 176 QSNPVLEAFGNAKTLRNDNSSRFGKYMDVQF-DFKGAPVGGHILSYLLEKSRVVHQNHGE 234
Query: 591 SNFLIFYLLMDGLSAEEKYGLHLN-NLCAHRYLNQTIQDDASTGERSLNREKLAVLKRAL 649
NF IFY L++G E L L N ++ YL ++ + ++ V+++AL
Sbjct: 235 RNFHIFYQLLEGGEEETLRRLGLERNPQSYLYL---VKGQCAKVSSINDKSDWKVVRKAL 291
Query: 650 NVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELA 709
V+ F+ EVE+L I+A++LHLG+I F A E N+ ++ QL + + +L V L
Sbjct: 292 TVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL-KYLTRLLSVEGSTLR 350
Query: 710 SALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSM 769
ALT KG+ ++ ++ A + RD LAK++YSR F++LV +N L S+D +
Sbjct: 351 EALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPS 410
Query: 770 --QTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMET 827
T +G+LDI+GFE FQ N FEQ C+N NEK+ E+ EQ E EG+ E
Sbjct: 411 WRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEP 470
Query: 828 AYSPGNQNGVLDFFFQKPSGFLTLLDEES-QMIWSVESNFPKKLQSLLESSNTNAVYSPM 886
N+ + D +K G +++LDEE + + + F +KL+ ++ + + + +
Sbjct: 471 VQYFNNKI-ICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVK-HHPHFLTHKL 528
Query: 887 KDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLF 946
D +L F ++HYAG V Y V G ++KN D L +NL M +S+N +++ F
Sbjct: 529 ADQRTRKSL--GRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCF 586
Query: 947 QSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQ 1006
+S L KK
Sbjct: 587 D---------------------RSELSDKKR----------------------------- 596
Query: 1007 RLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIG 1066
P T+A+Q + SL+ ++ LQ P ++ CI+PN++K P FD + Q++Y+G
Sbjct: 597 ------PETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLG 650
Query: 1067 VLEMVKIFRYGYPVRLSFSDFLSRYKPLA-DTFLREKKEQSAAERCRLVLQQCKLQGWQM 1125
+LE +++ R G+ R + FL RYK L +T+ + K + ++M
Sbjct: 651 LLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKM 710
Query: 1126 GVRKVFLKYWHADQLNDLCLQLQRKIIT--CQKVIRGFLARQHLLQ 1169
G K+F+++ + L+++R+ + Q RGF RQ L+
Sbjct: 711 GRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLR 756
>gi|124494240 myosin IC isoform c [Homo sapiens]
Length = 1028
Score = 329 bits (844), Expect = 1e-89
Identities = 238/766 (31%), Positives = 386/766 (50%), Gaps = 77/766 (10%)
Query: 413 NDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPH 472
++ + + +++RF N IYT+IG +L+ VNPY++L IYS + Y G +PPH
Sbjct: 24 SEAAFIENLRRRFRENLIYTYIGPVLVSVNPYRDLQIYSRQHMERY---RGVSFYEVPPH 80
Query: 473 LFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHL--TCRAGASRATLDSRFK 530
LF+ + + L E+R Q ++SGE G+GK+EA+K++++ TC A + R
Sbjct: 81 LFAVADTVYRALRTERRDQAVMISGESGAGKTEATKRLLQFYAETCPAPERGGAVRDRLL 140
Query: 531 HVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQ 590
+LEAFG+AKT ND SS F KY ++QF + K G I +YLLEKSR+V Q G+
Sbjct: 141 QSNPVLEAFGNAKTLRNDNSSRFGKYMDVQF-DFKGAPVGGHILSYLLEKSRVVHQNHGE 199
Query: 591 SNFLIFYLLMDGLSAEEKYGLHLN-NLCAHRYLNQTIQDDASTGERSLNREKLAVLKRAL 649
NF IFY L++G E L L N ++ YL ++ + ++ V+++AL
Sbjct: 200 RNFHIFYQLLEGGEEETLRRLGLERNPQSYLYL---VKGQCAKVSSINDKSDWKVVRKAL 256
Query: 650 NVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELA 709
V+ F+ EVE+L I+A++LHLG+I F A E N+ ++ QL + + +L V L
Sbjct: 257 TVIDFTEDEVEDLLSIVASVLHLGNIHFAANEESNAQVTTENQL-KYLTRLLSVEGSTLR 315
Query: 710 SALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSM 769
ALT KG+ ++ ++ A + RD LAK++YSR F++LV +N L S+D +
Sbjct: 316 EALTHRKIIAKGEELLSPLNLEQAAYARDALAKAVYSRTFTWLVGKINRSLASKDVESPS 375
Query: 770 --QTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMET 827
T +G+LDI+GFE FQ N FEQ C+N NEK+ E+ EQ E EG+ E
Sbjct: 376 WRSTTVLGLLDIYGFEVFQHNSFEQFCINYCNEKLQQLFIELTLKSEQEEYEAEGIAWEP 435
Query: 828 AYSPGNQNGVLDFFFQKPSGFLTLLDEES-QMIWSVESNFPKKLQSLLESSNTNAVYSPM 886
N+ + D +K G +++LDEE + + + F +KL+ ++ + + + +
Sbjct: 436 VQYFNNKI-ICDLVEEKFKGIISILDEECLRPGEATDLTFLEKLEDTVK-HHPHFLTHKL 493
Query: 887 KDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLF 946
D +L F ++HYAG V Y V G ++KN D L +NL M +S+N +++ F
Sbjct: 494 ADQRTRKSL--GRGEFRLLHYAGEVTYSVTGFLDKNNDLLFRNLKETMCSSKNPIMSQCF 551
Query: 947 QSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQ 1006
+S L KK
Sbjct: 552 D---------------------RSELSDKKR----------------------------- 561
Query: 1007 RLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIG 1066
P T+A+Q + SL+ ++ LQ P ++ CI+PN++K P FD + Q++Y+G
Sbjct: 562 ------PETVATQFKMSLLQLVEILQSKEPAYVRCIKPNDAKQPGRFDEVLIRHQVKYLG 615
Query: 1067 VLEMVKIFRYGYPVRLSFSDFLSRYKPLA-DTFLREKKEQSAAERCRLVLQQCKLQGWQM 1125
+LE +++ R G+ R + FL RYK L +T+ + K + ++M
Sbjct: 616 LLENLRVRRAGFAYRRKYEAFLQRYKSLCPETWPTWAGRPQDGVAVLVRHLGYKPEEYKM 675
Query: 1126 GVRKVFLKYWHADQLNDLCLQLQRKIIT--CQKVIRGFLARQHLLQ 1169
G K+F+++ + L+++R+ + Q RGF RQ L+
Sbjct: 676 GRTKIFIRFPKTLFATEDALEVRRQSLATKIQAAWRGFHWRQKFLR 721
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 328 bits (841), Expect = 3e-89
Identities = 249/799 (31%), Positives = 395/799 (49%), Gaps = 89/799 (11%)
Query: 389 STKPEQVKLMPPAPN-------DDLATLSELNDGSLLYEIQKRFGNNQ-IYTFIGDILLL 440
S PE +PP N +DL LS L++ ++L+ ++ RF ++ IYT+ G IL+
Sbjct: 51 SVNPES---LPPLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVA 107
Query: 441 VNPYKELPIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERG 500
+NPYK+LPIY + Y SG+ + PH+F+ E A+ Q+ R R Q I+SGE G
Sbjct: 108 MNPYKQLPIYGDAIIHAY---SGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESG 164
Query: 501 SGKSEASKQIIRHL-TCRAGASRATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFEL 559
+GK+ +++ +R+ T S A ++ + I EA G+AKTT ND SS F KY E+
Sbjct: 165 AGKTVSARYAMRYFATVSKSGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEI 224
Query: 560 QFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAH 619
F E+ Q + GA + TYLLEKSR+V Q + N+ IFY L SA++ HL A
Sbjct: 225 SFDEQNQ-IIGANMSTYLLEKSRVVFQSENERNYHIFYQLC--ASAQQSEFKHLKLGSAE 281
Query: 620 RYLNQTIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTA 679
+ N T + E +R ++ ++ ++GF ++F ILAAILHLG+++ TA
Sbjct: 282 EF-NYTRMGGNTVIEGVNDRAEMVETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITA 340
Query: 680 LNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDL 739
+ S+ D L+ +L + + +A L + +++ T A RD
Sbjct: 341 VGNERSSVSEDDSHLKVFCELLGLESGRVAQWLCNRKIVTSSETVVKPMTRPQAVNARDA 400
Query: 740 LAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTN 799
LAK +Y+ LF F+V +N L +Q + IG+LDI+GFE F N FEQ C+N N
Sbjct: 401 LAKKIYAHLFDFIVERINQALQFSGKQHTF----IGVLDIYGFETFDVNSFEQFCINYAN 456
Query: 800 EKMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMI 859
EK+ N +F EQ E ++E + NQ V+D K G L LLDEE +
Sbjct: 457 EKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQ-PVIDLIEAK-MGILELLDEECLLP 514
Query: 860 WSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAI 919
+ N+ +KL + N N ++ + N T+F I H+A +V Y G +
Sbjct: 515 HGTDENWLQKLYN--NFVNRNPLFEKPRMSN---------TSFVIQHFADKVEYKCEGFL 563
Query: 920 EKNKDSLSQNLLFVMKTSENVVINHLFQ---SKLSQTGSLVSAYPSFKFRGHKSALLSKK 976
EKN+D++ L+ +++ S+ + + FQ + S GS+++
Sbjct: 564 EKNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPFGSMITV----------------- 606
Query: 977 MTASSIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTP 1036
+A +I N + T+ S+ R SL ++ L TP
Sbjct: 607 KSAKQVIKPNSKHFR----------------------TTVGSKFRSSLYLLMETLNATTP 644
Query: 1037 HFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLAD 1096
H++ CI+PN+ KLP FD+ + QL+ GVLE ++I YP R ++ +F SRY
Sbjct: 645 HYVRCIKPNDEKLPFEFDSKRIVQQLRACGVLETIRISAQSYPSRWTYIEFYSRY----- 699
Query: 1097 TFLREKKEQSAAER---CRLVLQQC--KLQGWQMGVRKVFLKYWHADQLNDLCL-QLQRK 1150
L K+E S +++ C++VL + +Q G K+F + L L L +L++
Sbjct: 700 GILMTKQELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIFFRAGQVAYLEKLRLDKLRQS 759
Query: 1151 IITCQKVIRGFLARQHLLQ 1169
+ QK +RG+L R+ L+
Sbjct: 760 CVMVQKHMRGWLQRKKFLR 778
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 326 bits (835), Expect = 1e-88
Identities = 243/798 (30%), Positives = 399/798 (50%), Gaps = 100/798 (12%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQ-IYTFIGDILLLVNPYKELPIYSSMVSQLYFSSS 462
+DL LS L++ ++L+ ++ RF +++ IYT+ G +L+ +NPY++LPIY + Y S
Sbjct: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAY---S 128
Query: 463 GKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAG-AS 521
G+ + PH+F+ E A+ Q+ R++R Q I+SGE G+GK+ ++K +R+ +G AS
Sbjct: 129 GQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS 188
Query: 522 RATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKS 581
A ++ + I+E+ G+AKTT ND SS F KY E+ F +++ ++ GA + TYLLEKS
Sbjct: 189 EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGF-DKRYRIIGANMRTYLLEKS 247
Query: 582 RLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREK 641
R+V Q + N+ IFY L E L L N Y T Q + E + ++
Sbjct: 248 RVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNY---TKQGGSPVIEGVDDAKE 304
Query: 642 LAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGML 701
+A ++A ++G S +F ILA ILHLG++ FT+ + + + L ++
Sbjct: 305 MAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLM 364
Query: 702 QVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLH 761
V +E+ L + I+ + A RD LAK +Y++LF+++V+ +N LH
Sbjct: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
Query: 762 SQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQE 821
S +Q S IG+LDI+GFE F+ N FEQ C+N NEK+ N +F EQ E ++E
Sbjct: 425 SAVKQHSF----IGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Query: 822 GVTMETAYSPGNQNGVLDFFFQKPS--------GFLTLLDEESQMIWSVESNFPKKLQSL 873
+ ++DF+ +P G L LLDEE +M + + +KL +
Sbjct: 481 QIPWT----------LIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYN- 529
Query: 874 LESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFV 933
N A++ + N AF I H+A +V Y G +EKNKD++ + + V
Sbjct: 530 -THLNKCALFEKPRLSN---------KAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKV 579
Query: 934 MKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELS 993
+K+S+ ++ LFQ K ++ +S + L +
Sbjct: 580 LKSSKFKMLPELFQDD------------------------EKAISPTSATSSGRTPLTRT 615
Query: 994 KLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTF 1053
KG ++ + T+ Q R SL ++ L TPH++ CI+PN+ K P TF
Sbjct: 616 PAKPTKGRP---GQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTF 672
Query: 1054 DNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQS-AAERCR 1112
D QL+ GVLE ++I G+P R ++ +F SRY+ L +++K S + C+
Sbjct: 673 DEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVL----MKQKDVLSDRKQTCK 728
Query: 1113 LVLQQCKL--QGWQMGVRKVF--------LKYWHADQLNDLCLQLQRKI----------- 1151
VL++ L +Q G K+F L+ AD+L C+++Q+ I
Sbjct: 729 NVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLR 788
Query: 1152 -----ITCQKVIRGFLAR 1164
IT Q+ +RG+ AR
Sbjct: 789 MRKAAITMQRYVRGYQAR 806
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 326 bits (835), Expect = 1e-88
Identities = 243/798 (30%), Positives = 399/798 (50%), Gaps = 100/798 (12%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQ-IYTFIGDILLLVNPYKELPIYSSMVSQLYFSSS 462
+DL LS L++ ++L+ ++ RF +++ IYT+ G +L+ +NPY++LPIY + Y S
Sbjct: 72 NDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPIYGEDIINAY---S 128
Query: 463 GKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAG-AS 521
G+ + PH+F+ E A+ Q+ R++R Q I+SGE G+GK+ ++K +R+ +G AS
Sbjct: 129 GQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMRYFATVSGSAS 188
Query: 522 RATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKS 581
A ++ + I+E+ G+AKTT ND SS F KY E+ F +++ ++ GA + TYLLEKS
Sbjct: 189 EANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGF-DKRYRIIGANMRTYLLEKS 247
Query: 582 RLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREK 641
R+V Q + N+ IFY L E L L N Y T Q + E + ++
Sbjct: 248 RVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGNADNFNY---TKQGGSPVIEGVDDAKE 304
Query: 642 LAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQVAGML 701
+A ++A ++G S +F ILA ILHLG++ FT+ + + + L ++
Sbjct: 305 MAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIPPKHEPLCIFCDLM 364
Query: 702 QVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLH 761
V +E+ L + I+ + A RD LAK +Y++LF+++V+ +N LH
Sbjct: 365 GVDYEEMCHWLCHRKLATATETYIKPISKLQATNARDALAKHIYAKLFNWIVDNVNQALH 424
Query: 762 SQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQE 821
S +Q S IG+LDI+GFE F+ N FEQ C+N NEK+ N +F EQ E ++E
Sbjct: 425 SAVKQHSF----IGVLDIYGFETFEINSFEQFCINYANEKLQQQFNMHVFKLEQEEYMKE 480
Query: 822 GVTMETAYSPGNQNGVLDFFFQKPS--------GFLTLLDEESQMIWSVESNFPKKLQSL 873
+ ++DF+ +P G L LLDEE +M + + +KL +
Sbjct: 481 QIPWT----------LIDFYDNQPCINLIESKLGILDLLDEECKMPKGTDDTWAQKLYN- 529
Query: 874 LESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLFV 933
N A++ + N AF I H+A +V Y G +EKNKD++ + + V
Sbjct: 530 -THLNKCALFEKPRLSN---------KAFIIQHFADKVEYQCEGFLEKNKDTVFEEQIKV 579
Query: 934 MKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLELS 993
+K+S+ ++ LFQ K ++ +S + L +
Sbjct: 580 LKSSKFKMLPELFQDD------------------------EKAISPTSATSSGRTPLTRT 615
Query: 994 KLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDTF 1053
KG ++ + T+ Q R SL ++ L TPH++ CI+PN+ K P TF
Sbjct: 616 PAKPTKGRP---GQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKPNDFKFPFTF 672
Query: 1054 DNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQS-AAERCR 1112
D QL+ GVLE ++I G+P R ++ +F SRY+ L +++K S + C+
Sbjct: 673 DEKRAVQQLRACGVLETIRISAAGFPSRWTYQEFFSRYRVL----MKQKDVLSDRKQTCK 728
Query: 1113 LVLQQCKL--QGWQMGVRKVF--------LKYWHADQLNDLCLQLQRKI----------- 1151
VL++ L +Q G K+F L+ AD+L C+++Q+ I
Sbjct: 729 NVLEKLILDKDKYQFGKTKIFFRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLR 788
Query: 1152 -----ITCQKVIRGFLAR 1164
IT Q+ +RG+ AR
Sbjct: 789 MRKAAITMQRYVRGYQAR 806
>gi|55956916 myosin IE [Homo sapiens]
Length = 1108
Score = 326 bits (835), Expect = 1e-88
Identities = 241/785 (30%), Positives = 390/785 (49%), Gaps = 108/785 (13%)
Query: 404 DDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSSG 463
DD+ LS++ + S++ ++KR+ ++ I+T+IG +L+ VNP+K++P + ++Y G
Sbjct: 22 DDMVLLSKITENSIVENLKKRYMDDYIFTYIGSVLISVNPFKQMPYFGEKEIEMY---QG 78
Query: 464 KLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAGASRA 523
PPH+++ + + + ++ QC I+SGE G+GK+ A+K I+ +++ +G
Sbjct: 79 AAQYENPPHIYALADNMYRNMIIDRENQCVIISGESGAGKTVAAKYIMSYISRVSGGG-- 136
Query: 524 TLDSRFKHVVC----ILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLE 579
T K ++ +LEAFG+AKT N+ SS F KYFE+QF + G +I +LLE
Sbjct: 137 TKVQHVKDIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSPGGEP-DGGKISNFLLE 195
Query: 580 KSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQ---DDASTGERS 636
KSR+V + G+ +F IFY L++G SAE+K+ L + ++ + YL+ + DD
Sbjct: 196 KSRVVMRNPGERSFHIFYQLIEGASAEQKHSLGITSMDYYYYLSLSGSYKVDDID----- 250
Query: 637 LNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQLLEQ 696
+R + A+NV+G + E + I+A ILHLG+I F + GN A V + L
Sbjct: 251 -DRREFQETLHAMNVIGIFAEEQTLVLQIVAGILHLGNISFKEV--GNYAAVESEEFLAF 307
Query: 697 VAGMLQVSTDELASALTT---DIQYF-KGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFL 752
A +L ++ D L LT+ D ++ K + I ++ A + RD LAK+L++R+F FL
Sbjct: 308 PAYLLGINQDRLKEKLTSRQMDSKWGGKSESIHVTLNVEQACYTRDALAKALHARVFDFL 367
Query: 753 VNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFL 812
V+++N + E+ +IG+LDI+GFE FQKN FEQ C+N NEK+ E+
Sbjct: 368 VDSINKAMEKDHEE-----YNIGVLDIYGFEIFQKNGFEQFCINFVNEKLQQIFIELTLK 422
Query: 813 HEQVECVQEGVTMETAYSPGNQNGVLDFFFQK--PSGFLTLLDEESQMIWSV-ESNFPKK 869
EQ E VQEG+ T N V D K P G +++LD+ + +V E
Sbjct: 423 AEQEEYVQEGIRW-TPIEYFNNKIVCDLIENKVNPPGIMSILDDVCATMHAVGEGADQTL 481
Query: 870 LQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQN 929
LQ L ++ ++ G F I HYAG+V YD+ G E+N+D L +
Sbjct: 482 LQKLQMQIGSHEHFNSWNQG------------FIIHHYAGKVSYDMDGFCERNRDVLFMD 529
Query: 930 LLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNY 989
L+ +M++SE I LF L
Sbjct: 530 LIELMQSSELPFIKSLFPENLQ-------------------------------------- 551
Query: 990 LELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKL 1049
KKG P T S+++K D++ L KCTPH+I CI+PN +K
Sbjct: 552 ------ADKKGR-----------PTTAGSKIKKQANDLVSTLMKCTPHYIRCIKPNETKK 594
Query: 1050 PDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLAD-TFLREKKEQSAA 1108
P ++ V Q++Y+G+ E +++ R GY R F FL RY L T+ + E+
Sbjct: 595 PRDWEESRVKHQVEYLGLKENIRVRRAGYAYRRIFQKFLQRYAILTKATWPSWQGEEKQG 654
Query: 1109 ERCRLVLQQCKLQGWQMGVRKVFLK----YWHADQLNDLCLQLQRKIITCQKVIRGFLAR 1164
L +Q+G KVF+K + +++ + ++I QK R F+AR
Sbjct: 655 VLHLLQSVNMDSDQFQLGRSKVFIKAPESLFLLEEMRERKYDGYARVI--QKSWRKFVAR 712
Query: 1165 QHLLQ 1169
+ +Q
Sbjct: 713 KKYVQ 717
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 314 bits (804), Expect = 6e-85
Identities = 245/864 (28%), Positives = 424/864 (49%), Gaps = 91/864 (10%)
Query: 350 PIAKQDSLLEKDIMFKDATKGL----CKQQSQDSIPENPMMSGST----KPEQVKLMPP- 400
P+A+ D ++ + +G K++ D + + +G K + K+ PP
Sbjct: 24 PVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPK 83
Query: 401 -APNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYF 459
+ +D+A L+ LN+ S+L+ +++R+ + IYT+ G ++VNPYK LPIYS + +Y
Sbjct: 84 FSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY- 142
Query: 460 SSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAG 519
GK +PPH+++ + A+ + +++ Q + +GE G+GK+E +K++I++L A
Sbjct: 143 --KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
Query: 520 ASRAT--------LDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGA 571
+ + L+ + ILEAFG+AKT ND SS F K+ + F + + GA
Sbjct: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF-DVTGYIVGA 259
Query: 572 RIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDAS 631
I TYLLEKSR + Q + F IFY ++ G + + L L + +L+ +
Sbjct: 260 NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPA 319
Query: 632 TGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDL 691
+ + +E + A+ ++GFS E ++ +++++L LG+I F + A + D
Sbjct: 320 AQDDEMFQETV----EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDN 375
Query: 692 QLLEQVAGMLQVS-TDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFS 750
++V ++ ++ TD S LT I+ + D++ + T + A+F + LAK+ Y RLF
Sbjct: 376 TAAQKVCHLMGINVTDFTRSILTPRIKVGR-DVVQKAQTKEQADFAVEALAKATYERLFR 434
Query: 751 FLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVL 810
+++ +N L Q + +GILDI GFE F+ N FEQLC+N TNEK+ N +
Sbjct: 435 WILTRVNKALDKTHRQGASF---LGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTM 491
Query: 811 FLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQ--KPSGFLTLLDEESQMIWSVESNFPK 868
F+ EQ E +EG+ + ++ + P G L LLDEE + + +F +
Sbjct: 492 FILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVE 551
Query: 869 KLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQ 928
KL E + P + LKD T F+I+HYAG+V Y+ + KN D L+
Sbjct: 552 KL--CTEQGSHPKFQKPKQ-------LKDK-TEFSIIHYAGKVDYNASAWLTKNMDPLND 601
Query: 929 NLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKN 988
N+ ++ S + + L++ G A KMT SS+ +K
Sbjct: 602 NVTSLLNASSDKFVADLWKDVDRIVGLDQMA----------------KMTESSLPSASKT 645
Query: 989 YLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSK 1048
KKG T+ ++ L ++ L+ TP+F+ CI PN+ K
Sbjct: 646 ---------KKGMFR-----------TVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEK 685
Query: 1049 LPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAA 1108
D F V QL+ GVLE ++I R G+P R+ F +F RY+ LA + K
Sbjct: 686 RSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAI-PKGFMDGK 744
Query: 1109 ERCRLVLQQCKLQG--WQMGVRKVFLK---YWHADQLNDLCLQLQRKIITCQKVIRGFLA 1163
+ C L+++ +L +++G K+F + H ++ D L++ I+ Q + RG+LA
Sbjct: 745 QACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERD--LKITDVIMAFQAMCRGYLA 802
Query: 1164 RQHLLQRISIRQQEVTSINSFLQN 1187
R+ + RQQ++T++ +N
Sbjct: 803 RKAFAK----RQQQLTAMKVIQRN 822
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 314 bits (804), Expect = 6e-85
Identities = 245/864 (28%), Positives = 424/864 (49%), Gaps = 91/864 (10%)
Query: 350 PIAKQDSLLEKDIMFKDATKGL----CKQQSQDSIPENPMMSGST----KPEQVKLMPP- 400
P+A+ D ++ + +G K++ D + + +G K + K+ PP
Sbjct: 24 PVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPK 83
Query: 401 -APNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYF 459
+ +D+A L+ LN+ S+L+ +++R+ + IYT+ G ++VNPYK LPIYS + +Y
Sbjct: 84 FSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY- 142
Query: 460 SSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAG 519
GK +PPH+++ + A+ + +++ Q + +GE G+GK+E +K++I++L A
Sbjct: 143 --KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
Query: 520 ASRAT--------LDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGA 571
+ + L+ + ILEAFG+AKT ND SS F K+ + F + + GA
Sbjct: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF-DVTGYIVGA 259
Query: 572 RIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDAS 631
I TYLLEKSR + Q + F IFY ++ G + + L L + +L+ +
Sbjct: 260 NIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPA 319
Query: 632 TGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDL 691
+ + +E + A+ ++GFS E ++ +++++L LG+I F + A + D
Sbjct: 320 AQDDEMFQETV----EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDN 375
Query: 692 QLLEQVAGMLQVS-TDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFS 750
++V ++ ++ TD S LT I+ + D++ + T + A+F + LAK+ Y RLF
Sbjct: 376 TAAQKVCHLMGINVTDFTRSILTPRIKVGR-DVVQKAQTKEQADFAVEALAKATYERLFR 434
Query: 751 FLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVL 810
+++ +N L Q + +GILDI GFE F+ N FEQLC+N TNEK+ N +
Sbjct: 435 WILTRVNKALDKTHRQGASF---LGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTM 491
Query: 811 FLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQ--KPSGFLTLLDEESQMIWSVESNFPK 868
F+ EQ E +EG+ + ++ + P G L LLDEE + + +F +
Sbjct: 492 FILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVE 551
Query: 869 KLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQ 928
KL E + P + LKD T F+I+HYAG+V Y+ + KN D L+
Sbjct: 552 KL--CTEQGSHPKFQKPKQ-------LKDK-TEFSIIHYAGKVDYNASAWLTKNMDPLND 601
Query: 929 NLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKN 988
N+ ++ S + + L++ G A KMT SS+ +K
Sbjct: 602 NVTSLLNASSDKFVADLWKDVDRIVGLDQMA----------------KMTESSLPSASKT 645
Query: 989 YLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSK 1048
KKG T+ ++ L ++ L+ TP+F+ CI PN+ K
Sbjct: 646 ---------KKGMFR-----------TVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEK 685
Query: 1049 LPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAA 1108
D F V QL+ GVLE ++I R G+P R+ F +F RY+ LA + K
Sbjct: 686 RSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAI-PKGFMDGK 744
Query: 1109 ERCRLVLQQCKLQG--WQMGVRKVFLK---YWHADQLNDLCLQLQRKIITCQKVIRGFLA 1163
+ C L+++ +L +++G K+F + H ++ D L++ I+ Q + RG+LA
Sbjct: 745 QACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERD--LKITDVIMAFQAMCRGYLA 802
Query: 1164 RQHLLQRISIRQQEVTSINSFLQN 1187
R+ + RQQ++T++ +N
Sbjct: 803 RKAFAK----RQQQLTAMKVIQRN 822
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 311 bits (797), Expect = 4e-84
Identities = 245/871 (28%), Positives = 424/871 (48%), Gaps = 98/871 (11%)
Query: 350 PIAKQDSLLEKDIMFKDATKGL----CKQQSQDSIPENPMMSGST----KPEQVKLMPP- 400
P+A+ D ++ + +G K++ D + + +G K + K+ PP
Sbjct: 24 PVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPK 83
Query: 401 -APNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYF 459
+ +D+A L+ LN+ S+L+ +++R+ + IYT+ G ++VNPYK LPIYS + +Y
Sbjct: 84 FSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY- 142
Query: 460 SSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAG 519
GK +PPH+++ + A+ + +++ Q + +GE G+GK+E +K++I++L A
Sbjct: 143 --KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
Query: 520 ASRAT---------------LDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCER 564
+ + L+ + ILEAFG+AKT ND SS F K+ + F +
Sbjct: 201 SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF-DV 259
Query: 565 KQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQ 624
+ GA I TYLLEKSR + Q + F IFY ++ G + + L L + +L+
Sbjct: 260 TGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSN 319
Query: 625 TIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGN 684
+ + + +E + A+ ++GFS E ++ +++++L LG+I F +
Sbjct: 320 GFVPIPAAQDDEMFQETV----EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTD 375
Query: 685 SAFVSDLQLLEQVAGMLQVS-TDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKS 743
A + D ++V ++ ++ TD S LT I+ + D++ + T + A+F + LAK+
Sbjct: 376 QASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGR-DVVQKAQTKEQADFAVEALAKA 434
Query: 744 LYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMH 803
Y RLF +++ +N L Q + +GILDI GFE F+ N FEQLC+N TNEK+
Sbjct: 435 TYERLFRWILTRVNKALDKTHRQGASF---LGILDIAGFEIFEVNSFEQLCINYTNEKLQ 491
Query: 804 HYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQ--KPSGFLTLLDEESQMIWS 861
N +F+ EQ E +EG+ + ++ + P G L LLDEE +
Sbjct: 492 QLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKA 551
Query: 862 VESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEK 921
+ +F +KL E + P + LKD T F+I+HYAG+V Y+ + K
Sbjct: 552 TDKSFVEKL--CTEQGSHPKFQKPKQ-------LKDK-TEFSIIHYAGKVDYNASAWLTK 601
Query: 922 NKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASS 981
N D L+ N+ ++ S + + L++ G A KMT SS
Sbjct: 602 NMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMA----------------KMTESS 645
Query: 982 IIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHC 1041
+ +K KKG T+ ++ L ++ L+ TP+F+ C
Sbjct: 646 LPSASKT---------KKGMFR-----------TVGQLYKEQLGKLMTTLRNTTPNFVRC 685
Query: 1042 IRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLRE 1101
I PN+ K D F V QL+ GVLE ++I R G+P R+ F +F RY+ LA +
Sbjct: 686 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAI-P 744
Query: 1102 KKEQSAAERCRLVLQQCKLQG--WQMGVRKVFLK---YWHADQLNDLCLQLQRKIITCQK 1156
K + C L+++ +L +++G K+F + H ++ D L++ I+ Q
Sbjct: 745 KGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERD--LKITDVIMAFQA 802
Query: 1157 VIRGFLARQHLLQRISIRQQEVTSINSFLQN 1187
+ RG+LAR+ + RQQ++T++ +N
Sbjct: 803 MCRGYLARKAFAK----RQQQLTAMKVIQRN 829
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 311 bits (797), Expect = 4e-84
Identities = 245/871 (28%), Positives = 424/871 (48%), Gaps = 98/871 (11%)
Query: 350 PIAKQDSLLEKDIMFKDATKGL----CKQQSQDSIPENPMMSGST----KPEQVKLMPP- 400
P+A+ D ++ + +G K++ D + + +G K + K+ PP
Sbjct: 24 PVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPK 83
Query: 401 -APNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYF 459
+ +D+A L+ LN+ S+L+ +++R+ + IYT+ G ++VNPYK LPIYS + +Y
Sbjct: 84 FSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMY- 142
Query: 460 SSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAG 519
GK +PPH+++ + A+ + +++ Q + +GE G+GK+E +K++I++L A
Sbjct: 143 --KGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
Query: 520 ASRAT---------------LDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCER 564
+ + L+ + ILEAFG+AKT ND SS F K+ + F +
Sbjct: 201 SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINF-DV 259
Query: 565 KQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQ 624
+ GA I TYLLEKSR + Q + F IFY ++ G + + L L + +L+
Sbjct: 260 TGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSN 319
Query: 625 TIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGN 684
+ + + +E + A+ ++GFS E ++ +++++L LG+I F +
Sbjct: 320 GFVPIPAAQDDEMFQETV----EAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTD 375
Query: 685 SAFVSDLQLLEQVAGMLQVS-TDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKS 743
A + D ++V ++ ++ TD S LT I+ + D++ + T + A+F + LAK+
Sbjct: 376 QASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGR-DVVQKAQTKEQADFAVEALAKA 434
Query: 744 LYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMH 803
Y RLF +++ +N L Q + +GILDI GFE F+ N FEQLC+N TNEK+
Sbjct: 435 TYERLFRWILTRVNKALDKTHRQGASF---LGILDIAGFEIFEVNSFEQLCINYTNEKLQ 491
Query: 804 HYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQ--KPSGFLTLLDEESQMIWS 861
N +F+ EQ E +EG+ + ++ + P G L LLDEE +
Sbjct: 492 QLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKA 551
Query: 862 VESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEK 921
+ +F +KL E + P + LKD T F+I+HYAG+V Y+ + K
Sbjct: 552 TDKSFVEKL--CTEQGSHPKFQKPKQ-------LKDK-TEFSIIHYAGKVDYNASAWLTK 601
Query: 922 NKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASS 981
N D L+ N+ ++ S + + L++ G A KMT SS
Sbjct: 602 NMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMA----------------KMTESS 645
Query: 982 IIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHC 1041
+ +K KKG T+ ++ L ++ L+ TP+F+ C
Sbjct: 646 LPSASKT---------KKGMFR-----------TVGQLYKEQLGKLMTTLRNTTPNFVRC 685
Query: 1042 IRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLRE 1101
I PN+ K D F V QL+ GVLE ++I R G+P R+ F +F RY+ LA +
Sbjct: 686 IIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAANAI-P 744
Query: 1102 KKEQSAAERCRLVLQQCKLQG--WQMGVRKVFLK---YWHADQLNDLCLQLQRKIITCQK 1156
K + C L+++ +L +++G K+F + H ++ D L++ I+ Q
Sbjct: 745 KGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERD--LKITDVIMAFQA 802
Query: 1157 VIRGFLARQHLLQRISIRQQEVTSINSFLQN 1187
+ RG+LAR+ + RQQ++T++ +N
Sbjct: 803 MCRGYLARKAFAK----RQQQLTAMKVIQRN 829
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 310 bits (795), Expect = 6e-84
Identities = 231/775 (29%), Positives = 376/775 (48%), Gaps = 79/775 (10%)
Query: 404 DDLATLSELNDGSLLYEIQKRF-GNNQIYTFIGDILLLVNPYKELPIYSSMVSQLYFSSS 462
+DL LS L++ ++L+ ++ RF +N IYT+ G +L+ +NPY++LPIY V Y S
Sbjct: 72 NDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDVIYTY---S 128
Query: 463 GKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEASKQIIRHLTCRAG-AS 521
G+ + PH+F+ E A+ Q+ R+++ Q I+SGE G+GK+ ++K +R+ G AS
Sbjct: 129 GQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATVGGSAS 188
Query: 522 RATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQFCERKQQLTGARIYTYLLEKS 581
++ + I+EA G+AKTT ND SS F KY ++ F +++ + GA + TYLLEKS
Sbjct: 189 ETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGF-DKRYHIIGANMRTYLLEKS 247
Query: 582 RLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHRYLNQTIQDDASTGERSLNREK 641
R+V Q + N+ IFY L E L L + Y T Q ++ E + E
Sbjct: 248 RVVFQADDERNYHIFYQLCAAAGLPEFKELALTSAEDFFY---TSQGGDTSIEGVDDAED 304
Query: 642 LAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTALNEGNSAFVSDLQL-LEQVAGM 700
++A ++G ++F I+A+ILHLG + A +G+S +S + L +
Sbjct: 305 FEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNFCRL 364
Query: 701 LQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLLAKSLYSRLFSFLVNTMNSCL 760
L V ++ L + ++ ++Q R+ LAK +Y++LF ++V +N L
Sbjct: 365 LGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQVINARNALAKHIYAQLFGWIVEHINKAL 424
Query: 761 HSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNEKMHHYINEVLFLHEQVECVQ 820
H+ +Q S IG+LDI+GFE F+ N FEQ C+N NEK+ N +F EQ E ++
Sbjct: 425 HTSLKQHSF----IGVLDIYGFETFEVNSFEQFCINYANEKLQQQFNSHVFKLEQEEYMK 480
Query: 821 EGVTMETAYSPGNQNGVLDFFFQKPS--------GFLTLLDEESQMIWSVESNFPKKLQS 872
E + ++DF+ +P G L LLDEE ++ + N+ +KL
Sbjct: 481 EQIPWT----------LIDFYDNQPCIDLIEAKLGILDLLDEECKVPKGTDQNWAQKLYD 530
Query: 873 LLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIEKNKDSLSQNLLF 932
S++ P + TAF I+H+A +V Y G +EKN+D++ + +
Sbjct: 531 --RHSSSQHFQKP----------RMSNTAFIIVHFADKVEYLSDGFLEKNRDTVYEEQIN 578
Query: 933 VMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTASSIIGENKNYLEL 992
++K S+ ++ LF + S S+ +S + + NK + +
Sbjct: 579 ILKASKFPLVADLFHDDKDPVPATTPGKGS-------SSKISVRSARPPMKVSNKEHKK- 630
Query: 993 SKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIHCIRPNNSKLPDT 1052
T+ Q R SL ++ L TPH++ CI+PN+ KLP
Sbjct: 631 ----------------------TVGHQFRTSLHLLMETLNATTPHYVRCIKPNDEKLPFH 668
Query: 1053 FDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLREKKEQSAAERCR 1112
FD QL+ GVLE ++I GYP R ++ DF +RY+ L RE CR
Sbjct: 669 FDPKRAVQQLRACGVLETIRISAAGYPSRWAYHDFFNRYRVLVKK--RELANTDKKAICR 726
Query: 1113 LVLQQC--KLQGWQMGVRKVFLKYWHADQLNDL-CLQLQRKIITCQKVIRGFLAR 1164
VL+ +Q G K+F + L L + + I QK +RG+L +
Sbjct: 727 SVLENLIKDPDKFQFGRTKIFFRAGQVAYLEKLRADKFRTATIMIQKTVRGWLQK 781
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 306 bits (785), Expect = 9e-83
Identities = 229/799 (28%), Positives = 384/799 (48%), Gaps = 82/799 (10%)
Query: 391 KPEQVKLMPPAPND---DLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYKEL 447
KPE V M P D D+A L+ LN+ ++LY ++ R+ + IYT+ G + VNPYK L
Sbjct: 73 KPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMIYTYSGLFCVTVNPYKWL 132
Query: 448 PIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSEAS 507
P+Y+ V + Y GK PPH+FS + A+ + ++ Q +++GE G+GK+ +
Sbjct: 133 PVYNPEVVEGY---RGKKRQEAPPHIFSISDNAYQFMLTDRENQSILITGESGAGKTVNT 189
Query: 508 KQIIRHLTCRAGAS----------RATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYF 557
K++I++ A + TL+ + +LEAFG+AKT ND SS F K+
Sbjct: 190 KRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAKTVRNDNSSRFGKFI 249
Query: 558 ELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLC 617
+ F +L A I TYLLEKSR+ Q + ++ IFY ++ E + L +
Sbjct: 250 RIHF-GTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILSNKKPEL---IELLLIT 305
Query: 618 AHRYLNQTIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRF 677
+ Y I + E+L A++++GF+ E L+ + A++H G+++F
Sbjct: 306 TNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLYKLTGAVMHYGNMKF 365
Query: 678 TALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFR 737
A ++ ++ A ++ +++ +L AL + + + T+
Sbjct: 366 KQKQREEQAEPDGTEVADKTAYLMGLNSSDLLKALCFPRVKVGNEYVTKGQTVDQVHHAV 425
Query: 738 DLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNM 797
+ L+KS+Y +LF ++V +N L ++ ++ IG+LDI GFE F+ N EQLC+N
Sbjct: 426 NALSKSVYEKLFLWMVTRINQQLDTKLPRQHF----IGVLDIAGFEIFEYNSLEQLCINF 481
Query: 798 TNEKMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQ 857
TNEK+ + N +F+ EQ E +EG+ T G +KP G ++L+EE
Sbjct: 482 TNEKLQQFFNHHMFVLEQEEYKKEGIEW-TFIDFGMDLAACIELIEKPMGIFSILEEECM 540
Query: 858 MIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVG 917
+ +++F KL + N + G F+++HYAG V Y V G
Sbjct: 541 FPKATDTSFKNKLYDQHLGKSNNFQKPKVVKGRAEAH-------FSLIHYAGTVDYSVSG 593
Query: 918 AIEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKM 977
+EKNKD L++ ++ + + S N ++ HL Y +F
Sbjct: 594 WLEKNKDPLNETVVGLYQKSSNRLLAHL--------------YATFA------------- 626
Query: 978 TASSIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPH 1037
TA + G+ K + KKKG+S T+++ R++L ++ L+ PH
Sbjct: 627 TADADSGKKK-------VAKKKGSSF----------QTVSALFRENLNKLMSNLRTTHPH 669
Query: 1038 FIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADT 1097
F+ CI PN +K P ++ V QL+ GVLE ++I R G+P R+ + DF RY+ L +
Sbjct: 670 FVRCIIPNETKTPGAMEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNAS 729
Query: 1098 FLREKKEQSAAERCRLVLQQCKLQ--GWQMGVRKVFLKYWHADQLNDLCLQLQRKIIT-C 1154
+ E + + + C +L + ++ G KVF K L ++ K+IT
Sbjct: 730 AIPEGQFIDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRT 789
Query: 1155 QKVIRGFLAR---QHLLQR 1170
Q V RGFL R Q ++QR
Sbjct: 790 QAVCRGFLMRVEFQKMVQR 808
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 306 bits (784), Expect = 1e-82
Identities = 233/820 (28%), Positives = 397/820 (48%), Gaps = 78/820 (9%)
Query: 382 ENPMMSGSTKPEQVKLMPP--APNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILL 439
EN K + K+ PP + +D+A L+ LN+ S+L+ +++R+ + IYT+ G +
Sbjct: 60 ENGKKVKVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCV 119
Query: 440 LVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGER 499
++NPYK LPIYS + ++Y GK +PPH+++ + A+ + +++ Q + +GE
Sbjct: 120 VINPYKNLPIYSEEIVEMY---KGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGES 176
Query: 500 GSGKSEASKQIIRHLTCRAGASRAT-----LDSRFKHVVCILEAFGHAKTTLNDLSSCFI 554
G+GK+E +K++I++L A + ++ L+ + ILEAFG+AKT ND SS F
Sbjct: 177 GAGKTENTKKVIQYLAYVASSHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFG 236
Query: 555 KYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLN 614
K+ + F + + GA I TYLLEKSR + Q + F IFY L+ G K L L
Sbjct: 237 KFIRINF-DVNGYIVGANIETYLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLE 295
Query: 615 NLCAHRYLNQTIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGD 674
+R+L+ ++ + +E + A+ ++G E L +++ +L LG+
Sbjct: 296 PYNKYRFLSNGHVTIPGQQDKDMFQETM----EAMRIMGIPEEEQMGLLRVISGVLQLGN 351
Query: 675 IRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAE 734
I F + A + D ++V+ +L ++ + + T D + + T + A+
Sbjct: 352 IVFKKERNTDQASMPDNTAAQKVSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQAD 411
Query: 735 FFRDLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLC 794
F + LAK+ Y R+F +LV +N L D+ K IGILDI GFE F N FEQLC
Sbjct: 412 FAIEALAKATYERMFRWLVLRINKAL---DKTKRQGASFIGILDIAGFEIFDLNSFEQLC 468
Query: 795 VNMTNEKMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQK--PSGFLTLL 852
+N TNEK+ N +F+ EQ E +EG+ + +D + P G L LL
Sbjct: 469 INYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPPGILALL 528
Query: 853 DEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVM 912
DEE + + +F +K +++ T+ + K LKD F I+HYAG+V
Sbjct: 529 DEECWFPKATDKSFVEK---VMQEQGTHPKFQKPKQ------LKDKAD-FCIIHYAGKVD 578
Query: 913 YDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSAL 972
Y + KN D L+ N+ ++ S + ++ L++
Sbjct: 579 YKADEWLMKNMDPLNDNIATLLHQSSDKFVSELWKD------------------------ 614
Query: 973 LSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQ 1032
IIG + +++ + + F R +G T+ ++ L ++ L+
Sbjct: 615 ------VDRIIGLD----QVAGMSETALPGAFKTR--KGMFRTVGQLYKEQLAKLMATLR 662
Query: 1033 KCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYK 1092
P+F+ CI PN+ K D V QL+ GVLE ++I R G+P R+ F +F RY+
Sbjct: 663 NTNPNFVRCIIPNHEKKAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRVVFQEFRQRYE 722
Query: 1093 PLADTFLREKKEQSAAERCRLVLQQCKLQG--WQMGVRKVFLK---YWHADQLNDLCLQL 1147
L + K + C L+++ +L +++G KVF + H ++ D L++
Sbjct: 723 ILTPNSI-PKGFMDGKQACVLMIKALELDSNLYRIGQSKVFFRAGVLAHLEEERD--LKI 779
Query: 1148 QRKIITCQKVIRGFLARQHLLQRISIRQQEVTSINSFLQN 1187
II Q RG+LAR+ + RQQ++T++ +N
Sbjct: 780 TDVIIGFQACCRGYLARKAFAK----RQQQLTAMKVLQRN 815
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 305 bits (781), Expect = 3e-82
Identities = 230/775 (29%), Positives = 371/775 (47%), Gaps = 74/775 (9%)
Query: 389 STKPEQVKLMPPAPND---DLATLSELNDGSLLYEIQKRFGNNQIYTFIGDILLLVNPYK 445
S K ++++ M P + D+A L+ LN+ S+L+ +++R+G IYT+ G + +NPYK
Sbjct: 88 SIKEDKIQQMNPPEFEMIEDMAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYK 147
Query: 446 ELPIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSGERGSGKSE 505
LP+Y V Y GK S PPH+F+ AF + + Q + +GE G+GK+
Sbjct: 148 WLPVYQKEVMAAY---KGKRRSEAPPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTV 204
Query: 506 ASKQIIRHLTCRAGA-----SRATLDSRFKHVVCILEAFGHAKTTLNDLSSCFIKYFELQ 560
SK II++ A + L+ + ILEAFG+AKT ND SS F K+ +
Sbjct: 205 NSKHIIQYFATIAAMIESRKKQGALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMH 264
Query: 561 FCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKYGLHLNNLCAHR 620
F R L+ I YLLEKSR++ Q G+ N+ IFY ++ G +E + L L + A+
Sbjct: 265 FGARGM-LSSVDIDIYLLEKSRVIFQQAGERNYHIFYQILSG--QKELHDLLL--VSANP 319
Query: 621 YLNQTIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAILHLGDIRFTAL 680
A T E + E+L ++A++++GF E + + AI+H G+++F
Sbjct: 320 SDFHFCSCGAVTVESLDDAEELLATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQK 379
Query: 681 NEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHTIQIAEFFRDLL 740
+ ++ A ++ +++ EL L + + R TI+ L
Sbjct: 380 PREEQLEADGTENADKAAFLMGINSSELVKCLIHPRIKVGNEYVTRGQTIEQVTCAVGAL 439
Query: 741 AKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNEFEQLCVNMTNE 800
+KS+Y R+F +LV +N L + K + IGILDI GFE + N EQLC+N TNE
Sbjct: 440 SKSMYERMFKWLVARINRAL----DAKLSRQFFIGILDITGFEILEYNSLEQLCINFTNE 495
Query: 801 KMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQKPSGFLTLLDEESQMIW 860
K+ + N +F+ EQ E +E + + + +D +KP G L++L+EE
Sbjct: 496 KLQQFFNWHMFVLEQEEYKKESIEWVSIGFGLDLQACID-LIEKPMGILSILEEECMFPK 554
Query: 861 SVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHYAGRVMYDVVGAIE 920
+ + F KL + + + P D K F ++HYAG V Y++ G +E
Sbjct: 555 ATDLTFKTKLFDNHFGKSVH-LQKPKPD------KKKFEAHFELVHYAGVVPYNISGWLE 607
Query: 921 KNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRGHKSALLSKKMTAS 980
KNKD L++ ++ V + S N ++ LF++ +S SA P
Sbjct: 608 KNKDLLNETVVAVFQKSSNRLLASLFENYMSTD----SAIP------------------- 644
Query: 981 SIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDIIGKLQKCTPHFIH 1040
GE K +KKG S T+AS +++L ++ L+ PHF+
Sbjct: 645 --FGEKK---------RKKGASF----------QTVASLHKENLNKLMTNLKSTAPHFVR 683
Query: 1041 CIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDFLSRYKPLADTFLR 1100
CI PN +K+P D + V QL+ GVLE +I R G+P RL ++DF RY L
Sbjct: 684 CINPNVNKIPGILDPYLVLQQLRCNGVLEGTRICREGFPNRLQYADFKQRYCILNPRTFP 743
Query: 1101 EKKEQSAAERCRLVLQQCKLQ--GWQMGVRKVFLKYWHADQLNDLCLQLQRKIIT 1153
+ K S+ + +L ++ ++ G+ KVF K QL + + K+ T
Sbjct: 744 KSKFVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGFLGQLEAIRDERLSKVFT 798
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 305 bits (780), Expect = 4e-82
Identities = 232/825 (28%), Positives = 404/825 (48%), Gaps = 81/825 (9%)
Query: 380 IPENPMMSGSTKPEQVKLMPP--APNDDLATLSELNDGSLLYEIQKRFGNNQIYTFIGDI 437
+ EN + K + K+ PP + +D+A L+ LN+ S+L+ ++ R+ + IYT+ G
Sbjct: 62 LAENGKKAMVNKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLF 121
Query: 438 LLLVNPYKELPIYSSMVSQLYFSSSGKLCSSLPPHLFSCVERAFHQLFREQRPQCFILSG 497
+++NPYK LPIYS + ++Y GK +PPH+++ E A+ + +++ Q + +G
Sbjct: 122 CVVINPYKNLPIYSENIIEMY---RGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTG 178
Query: 498 ERGSGKSEASKQIIRHLTCRAGASRAT--------LDSRFKHVVCILEAFGHAKTTLNDL 549
E G+GK+E +K++I++L A + + L+ + ILE+FG+AKT ND
Sbjct: 179 ESGAGKTENTKKVIQYLAHVASSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDN 238
Query: 550 SSCFIKYFELQFCERKQQLTGARIYTYLLEKSRLVSQPLGQSNFLIFYLLMDGLSAEEKY 609
SS F K+ + F + + GA I TYLLEKSR V Q + F IFY L+ G K
Sbjct: 239 SSRFGKFIRINF-DVTGYIVGANIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKS 297
Query: 610 GLHLNNLCAHRYLNQTIQDDASTGERSLNREKLAVLKRALNVVGFSSLEVENLFVILAAI 669
L L +R+L+ ++ +E + A++++GFS E+ ++ +++++
Sbjct: 298 DLLLEGFNNYRFLSNGYIPIPGQQDKDNFQETM----EAMHIMGFSHEEILSMLKVVSSV 353
Query: 670 LHLGDIRFTALNEGNSAFVSDLQLLEQVAGMLQVSTDELASALTTDIQYFKGDMIIRRHT 729
L G+I F + A + + + +++ +L ++ E A+ T D + + T
Sbjct: 354 LQFGNISFKKERNTDQASMPENTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQT 413
Query: 730 IQIAEFFRDLLAKSLYSRLFSFLVNTMNSCLHSQDEQKSMQTLDIGILDIFGFEEFQKNE 789
+ A+F + LAK+ Y RLF +LV+ +N L D K IGILDI GFE F+ N
Sbjct: 414 KEQADFAVEALAKATYERLFRWLVHRINKAL---DRTKRQGASFIGILDIAGFEIFELNS 470
Query: 790 FEQLCVNMTNEKMHHYINEVLFLHEQVECVQEGVTMETAYSPGNQNGVLDFFFQ--KPSG 847
FEQLC+N TNEK+ N +F+ EQ E +EG+ + +D + P G
Sbjct: 471 FEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPPG 530
Query: 848 FLTLLDEESQMIWSVESNFPKKLQSLLESSNTNAVYSPMKDGNGNVALKDHGTAFTIMHY 907
L LLDEE + + F +KL + E + + P + LKD F I+HY
Sbjct: 531 VLALLDEECWFPKATDKTFVEKL--VQEQGSHSKFQKPRQ-------LKDKAD-FCIIHY 580
Query: 908 AGRVMYDVVGAIEKNKDSLSQNLLFVMKTSENVVINHLFQSKLSQTGSLVSAYPSFKFRG 967
AG+V Y + KN D L+ N+ ++ S + + L++
Sbjct: 581 AGKVDYKADEWLMKNMDPLNDNVATLLHQSSDRFVAELWKD------------------- 621
Query: 968 HKSALLSKKMTASSIIGENKNYLELSKLLKKKGTSTFLQRLERGDPVTIASQLRKSLMDI 1027
I+G + +++ + + S + + ++G T+ ++SL +
Sbjct: 622 -----------VDRIVGLD----QVTGMTETAFGSAY--KTKKGMFRTVGQLYKESLTKL 664
Query: 1028 IGKLQKCTPHFIHCIRPNNSKLPDTFDNFYVSAQLQYIGVLEMVKIFRYGYPVRLSFSDF 1087
+ L+ P+F+ CI PN+ K D V QL+ GVLE ++I R G+P R+ F +F
Sbjct: 665 MATLRNTNPNFVRCIIPNHEKRAGKLDPHLVLDQLRCNGVLEGIRICRQGFPNRIVFQEF 724
Query: 1088 LSRYKPLADTFLREKKEQSAAERCRLVLQQCKLQG--WQMGVRKVFLK---YWHADQLND 1142
RY+ L + K + C +++ +L +++G K+F + H ++ D
Sbjct: 725 RQRYEILTPNAI-PKGFMDGKQACERMIRALELDPNLYRIGQSKIFFRAGVLAHLEEERD 783
Query: 1143 LCLQLQRKIITCQKVIRGFLARQHLLQRISIRQQEVTSINSFLQN 1187
L++ II Q V RG+LAR+ + +QQ+++++ +N
Sbjct: 784 --LKITDIIIFFQAVCRGYLARKAFAK----KQQQLSALKVLQRN 822
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,097,126
Number of Sequences: 37866
Number of extensions: 4715402
Number of successful extensions: 71634
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 951
Number of HSP's successfully gapped in prelim test: 1652
Number of HSP's that attempted gapping in prelim test: 27528
Number of HSP's gapped (non-prelim): 20258
length of query: 1858
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1741
effective length of database: 13,817,196
effective search space: 24055738236
effective search space used: 24055738236
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.