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Search of human proteins with 13514831
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
(875 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo sapi... 1728 0.0
gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo sapi... 378 e-104
gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo sapi... 304 2e-82
gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1 ... 242 1e-63
gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1 ... 231 2e-60
gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo sap... 215 2e-55
gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2 ... 201 3e-51
gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo sapi... 201 3e-51
gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1... 201 3e-51
gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2 ... 198 2e-50
gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo sapi... 185 2e-46
gi|21071032 DEAD-box protein abstrakt [Homo sapiens] 181 2e-45
gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens] 180 4e-45
gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens] 180 4e-45
gi|13129006 nucleolar protein GU2 [Homo sapiens] 177 3e-44
gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens] 176 1e-43
gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens] 176 1e-43
gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo sapi... 176 1e-43
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 174 2e-43
gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3 ... 174 4e-43
gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1 [... 174 4e-43
gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2 ... 174 4e-43
gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens] 173 5e-43
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi... 171 4e-42
gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo sap... 170 6e-42
gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo... 166 7e-41
gi|20336298 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 2 ... 166 7e-41
gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked ... 164 3e-40
gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked [... 164 3e-40
gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo sap... 161 2e-39
>gi|13514831 DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 [Homo
sapiens]
Length = 875
Score = 1728 bits (4475), Expect = 0.0
Identities = 875/875 (100%), Positives = 875/875 (100%)
Query: 1 MGKTANSPGSGARPDPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNY 60
MGKTANSPGSGARPDPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNY
Sbjct: 1 MGKTANSPGSGARPDPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNY 60
Query: 61 EKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKT 120
EKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKT
Sbjct: 61 EKINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKT 120
Query: 121 LAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKD 180
LAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKD
Sbjct: 121 LAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKD 180
Query: 181 LKHEAERINNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVI 240
LKHEAERINNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVI
Sbjct: 181 LKHEAERINNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVI 240
Query: 241 ENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQK 300
ENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQK
Sbjct: 241 ENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQK 300
Query: 301 ISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNE 360
ISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNE
Sbjct: 301 ISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNE 360
Query: 361 FVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILL 420
FVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILL
Sbjct: 361 FVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILL 420
Query: 421 PSEKAMVQQLLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVY 480
PSEKAMVQQLLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVY
Sbjct: 421 PSEKAMVQQLLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVY 480
Query: 481 LMKDKEVFDVSKLPIPEYALSLGLAVAPRVRFLQKMQKQPTKELVRSQADKVIEPRAPSL 540
LMKDKEVFDVSKLPIPEYALSLGLAVAPRVRFLQKMQKQPTKELVRSQADKVIEPRAPSL
Sbjct: 481 LMKDKEVFDVSKLPIPEYALSLGLAVAPRVRFLQKMQKQPTKELVRSQADKVIEPRAPSL 540
Query: 541 TNDEVEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEEMEEKLAKAK 600
TNDEVEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEEMEEKLAKAK
Sbjct: 541 TNDEVEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEEMEEKLAKAK 600
Query: 601 GSQAPSLPNTSEAQKIKEVPTQFLDRDEEEEDADFLKVKRHNVFGLDLKDEKTLQKKEPS 660
GSQAPSLPNTSEAQKIKEVPTQFLDRDEEEEDADFLKVKRHNVFGLDLKDEKTLQKKEPS
Sbjct: 601 GSQAPSLPNTSEAQKIKEVPTQFLDRDEEEEDADFLKVKRHNVFGLDLKDEKTLQKKEPS 660
Query: 661 KSSIKKKMTKVAEAKKVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDDDTGGI 720
KSSIKKKMTKVAEAKKVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDDDTGGI
Sbjct: 661 KSSIKKKMTKVAEAKKVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDDDTGGI 720
Query: 721 NLHKAKERLQEEDKFDKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWS 780
NLHKAKERLQEEDKFDKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWS
Sbjct: 721 NLHKAKERLQEEDKFDKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWS 780
Query: 781 DDDDDDDDGFDPSTLPDPDKYRSSEDSDSEDMENKISDTKKKQGMKKRSNSEVEDVGPTS 840
DDDDDDDDGFDPSTLPDPDKYRSSEDSDSEDMENKISDTKKKQGMKKRSNSEVEDVGPTS
Sbjct: 781 DDDDDDDDGFDPSTLPDPDKYRSSEDSDSEDMENKISDTKKKQGMKKRSNSEVEDVGPTS 840
Query: 841 HNRKKARWDTLEPLDTGLSLAEDEELVLHLLRSQS 875
HNRKKARWDTLEPLDTGLSLAEDEELVLHLLRSQS
Sbjct: 841 HNRKKARWDTLEPLDTGLSLAEDEELVLHLLRSQS 875
>gi|38327634 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 [Homo
sapiens]
Length = 670
Score = 378 bits (971), Expect = e-104
Identities = 212/505 (41%), Positives = 315/505 (62%), Gaps = 10/505 (1%)
Query: 12 ARPDPVRSFNRWK-KKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEKINVNEITR 70
A PD ++ K K K+ ++KP+ + + L E T
Sbjct: 121 AEPDTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLT--GAFEDTS 178
Query: 71 FSDFP--LSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVL 128
F+ +++ TLK ++E + +TEIQ ++I L+G+D+L AAKTGSGKTLAFL+P +
Sbjct: 179 FASLCNLVNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAV 238
Query: 129 EALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERI 188
E + +L++ +G GVLI+SPTRELA QTF VL+++ +H + GLI+GG + EA+++
Sbjct: 239 ELIVKLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKL 298
Query: 189 -NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKR 247
N INI+V TPGRLL HM T F +LQ LV+DEADRILD+GF + + +I+ LP +R
Sbjct: 299 GNGINIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRR 358
Query: 248 QTLLFSATQTKSVKDLARLSL-KNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYS 306
QT+LFSATQT+ V+DLAR+SL K P YV V + +T LEQ Y+VC +++ +L++
Sbjct: 359 QTMLFSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFT 418
Query: 307 FLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRA 366
FL+ + KKK +VFFSSC V+Y Y + + + +LA+HG+Q+Q +R + +F +
Sbjct: 419 FLKKNRKKKLMVFFSSCMSVKYHYELLNYI--DLPVLAIHGKQKQNKRTTTFFQFCNADS 476
Query: 367 AVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTAR-YKEDGEALLILLPSEKA 425
L TD+AARGLD P V+W++Q+D P+D YIHR GRTAR G ALLIL P E
Sbjct: 477 GTLLCTDVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTARGLNGRGHALLILRPEELG 536
Query: 426 MVQQLLQKKVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVYLMKDK 485
++ L Q KVP+ E + K+ D+Q +LE ++ ++ L + AQ + SY+R+ K
Sbjct: 537 FLRYLKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYFLHKSAQEAYKSYIRAYDSHSLK 596
Query: 486 EVFDVSKLPIPEYALSLGLAVAPRV 510
++F+V+ L +P+ ALS G V P V
Sbjct: 597 QIFNVNNLNLPQVALSFGFKVPPFV 621
>gi|41327779 DEAD (Asp-Glu-Ala-Asp) box polypeptide 55 [Homo
sapiens]
Length = 600
Score = 304 bits (779), Expect = 2e-82
Identities = 202/551 (36%), Positives = 311/551 (56%), Gaps = 39/551 (7%)
Query: 75 PLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRL 134
PL + L L+E + +T +Q TI L ++ KDV A TGSGKTLAF++P+LE L R
Sbjct: 15 PLHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILLRR 74
Query: 135 QWT-STDGLGVLIISPTRELAYQTFEVLRKVGKNH-DFSAGLIIGGKDLKHEAERINNI- 191
+ +G +II+PTRELA Q EVL K+ +FS L IGG++ + ER
Sbjct: 75 EEKLKKSQVGAIIITPTRELAIQIDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQG 134
Query: 192 -NILVCTPGRL---LQHMDETVSFHAT--DLQMLVLDEADRILDMGFADTMNAVIENLPK 245
NI+V TPGRL + E + + L +LVLDEADR+LDMGF ++N ++E LPK
Sbjct: 135 GNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPK 194
Query: 246 KRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEK-----AKYSTPATLEQNYIVCELQQK 300
+R+T LFSATQT+ V++L R L+NP V V EK + TP+ LE Y+VC+ +K
Sbjct: 195 QRRTGLFSATQTQEVENLVRAGLRNPVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEK 254
Query: 301 ISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNE 360
+ L FLR+H ++K +VFFS+C V+Y + L GV I+ +HG+ + +R +++ E
Sbjct: 255 FNQLVHFLRNHKQEKHLVFFSTCACVEYYGKALEVLVKGVKIMCIHGKMKY-KRNKIFME 313
Query: 361 FVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILL 420
F + ++ +L TD+ ARG+D P VNWVLQ+D P +A+ ++HR GRTAR G AL+ LL
Sbjct: 314 FRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTARIGHGGSALVFLL 373
Query: 421 PSEKAMVQQL-LQKKVPVKEIKINPEK-LIDVQKKLESILAQDQDLKERAQRCFVSYVRS 478
P E++ + L + +K P++E+K P++ D+ KL+S+ D+ + E+ + FVSYV++
Sbjct: 374 PMEESYINFLAINQKCPLQEMK--PQRNTADLLPKLKSMALADRAVFEKGMKAFVSYVQA 431
Query: 479 VYLMKDKEVFDVSKLPIPEYALSLGLAVAPRVRFLQKMQ------------KQPTKELVR 526
+ +F + L A L P++ L+ Q P K+ +R
Sbjct: 432 YAKHECNLIFRLKDLDFASLARGFALLRMPKMPELRGKQFPDFVPVDVNTDTIPFKDKIR 491
Query: 527 -SQADKVIEPRAPSLTNDEVEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEEQEEE 585
Q K++E + T +E R + K QK K E ++ + + +E
Sbjct: 492 EKQRQKLLEQQRREKTENEGR--RKFIKNKAWSKQKAKK-----EKKKKMNEKRKREEGS 544
Query: 586 EDDEEEMEEKL 596
+ ++E+MEE L
Sbjct: 545 DIEDEDMEELL 555
Score = 37.4 bits (85), Expect = 0.061
Identities = 32/130 (24%), Positives = 62/130 (47%), Gaps = 13/130 (10%)
Query: 736 DKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSDDDDDDDDGFDPSTL 795
D ++ KI+ K R+K L+++ RRE + + + K + WS + +
Sbjct: 482 DTIPFKDKIREKQRQKLLEQQ--RREKTENEGRRKFIKNKA--WSKQKAKKEK---KKKM 534
Query: 796 PDPDKYRSSEDSDSEDMENKISDTKKKQGMKKRSNSEVE-DVGPTSHNRKKARWDTLEPL 854
+ K D + EDME ++DT+ + +KK +E E + G + ++ T++ +
Sbjct: 535 NEKRKREEGSDIEDEDMEELLNDTRLLKKLKKGKITEEEFEKGLLTTGKR-----TIKTV 589
Query: 855 DTGLSLAEDE 864
D G+S ED+
Sbjct: 590 DLGISDLEDD 599
>gi|17505907 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 1
[Homo sapiens]
Length = 851
Score = 242 bits (618), Expect = 1e-63
Identities = 172/503 (34%), Positives = 258/503 (51%), Gaps = 87/503 (17%)
Query: 92 VTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWT--STDGLGVLIISP 149
+T +QKQ+I + L+G+D L ++TGSGKTLA+ +PV+++L ++ +DG L++ P
Sbjct: 254 MTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVP 313
Query: 150 TRELAYQTFEVLRKVGKNHDFSA-GLIIGGKDLKHEAERINN-INILVCTPGRLLQHMDE 207
TRELA Q+F+ ++K+ K + G+++GG+ K E R+ INIL+ TPGRL+ H+
Sbjct: 314 TRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKS 373
Query: 208 TVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLP---KKRQTLLFSATQTKSVKDLA 264
T + H + L+ LV DEADRILD+GF + ++ + +KRQ +L SAT T+ V LA
Sbjct: 374 TKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLA 433
Query: 265 RLSLKNPEYVWVHEKA------------------------KYSTPATLEQNYIVCELQQK 300
+SL +P + V +K+ ++ P +L+Q+ V + +
Sbjct: 434 DISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLR 493
Query: 301 ISVLYSFLRSHLK----KKSIVFFSSCKEVQYLYRVFCRLR------------PGVSI-- 342
+ L +F+ K +K +VFFSSC+ V++ Y +F + P S+
Sbjct: 494 LVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRL 553
Query: 343 --LALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYI 400
L LHG +Q R V+ EF R VL TD+AARGLD P V W++Q++ P YI
Sbjct: 554 KFLRLHGGMEQEERTAVFQEFSHSRRGVLLCTDVAARGLDLPQVTWIVQYNAPSSPAEYI 613
Query: 401 HRAGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVKEIKINPEKLIDVQKK------- 453
HR GRTAR G +LLIL PSE V L K+ V EIK+ E ++ V +
Sbjct: 614 HRIGRTARIGCHGSSLLILAPSEAEYVNSLASHKINVSEIKM--EDILCVLTRDDCFKGK 671
Query: 454 ----LESILAQDQDLKERA---QRCFVSYVRS--------------------VYLMKDKE 486
+S Q+++ERA Q F YV S Y + K
Sbjct: 672 RWGAQKSHAVGPQEIRERATVLQTVFEDYVHSSERRVSWAKKALQSFIQAYATYPRELKH 731
Query: 487 VFDVSKLPIPEYALSLGLAVAPR 509
+F V L + A S GL APR
Sbjct: 732 IFHVRSLHLGHVAKSFGLRDAPR 754
>gi|20149629 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 1
[Homo sapiens]
Length = 455
Score = 231 bits (590), Expect = 2e-60
Identities = 141/416 (33%), Positives = 229/416 (55%), Gaps = 17/416 (4%)
Query: 63 INVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLA 122
+ E F D ++ + + + T+IQ + I LALQG+D++G A+TGSGKT A
Sbjct: 18 VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77
Query: 123 FLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
F +P+L AL + L L+++PTRELA+Q E +G + + +I+GG D
Sbjct: 78 FALPILNALLE----TPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSM 133
Query: 183 HEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
++ + +I++ TPGRL+ H++ T F+ L+ LV+DEADRIL+M F ++ +++
Sbjct: 134 SQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILK 193
Query: 242 NLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKI 301
+P+ R+T LFSAT TK V+ L R +LKNP V +KY T L+Q YI + K
Sbjct: 194 VIPRDRKTFLFSATMTKKVQKLQRAALKNP--VKCAVSSKYQTVEKLQQYYIFIPSKFKD 251
Query: 302 SVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEF 361
+ L L ++F S+C Q + L G + + LHG+ Q +R+ N+F
Sbjct: 252 TYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNL--GFTAIPLHGQMSQSKRLGSLNKF 309
Query: 362 VRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLP 421
K ++L ATD+A+RGLD P V+ V+ FD P + YIHR GRTAR G+A+ +
Sbjct: 310 KAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 369
Query: 422 SEKAM---VQQLLQKKVP-----VKEIKINPEKLIDVQKKLESILAQDQDLKERAQ 469
+ + ++ L+ KK+P E+ + E++ + Q+ L + + K+R++
Sbjct: 370 YDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSR 425
>gi|224593278 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 [Homo
sapiens]
Length = 796
Score = 215 bits (547), Expect = 2e-55
Identities = 133/395 (33%), Positives = 211/395 (53%), Gaps = 6/395 (1%)
Query: 66 NEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLV 125
+E F D LS+ LK + ++ T IQK I + L GKD+ A TG+GKT AF +
Sbjct: 215 DENLSFQDMNLSRPLLKAITAMGFKQPTPIQKACIPVGLLGKDICACAATGTGKTAAFAL 274
Query: 126 PVLEAL-YRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHE 184
PVLE L Y+ + VL++ PTREL Q V R++ + + + L +GG D+K +
Sbjct: 275 PVLERLIYKPRQAPVTR--VLVLVPTRELGIQVHSVTRQLAQFCNITTCLAVGGLDVKSQ 332
Query: 185 AERINNI-NILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENL 243
+ +IL+ TPGRL+ H+ SFH + +++L+LDEADR+LD F + M +I
Sbjct: 333 EAALRAAPDILIATPGRLIDHLHNCPSFHLSSIEVLILDEADRMLDEYFEEQMKEIIRMC 392
Query: 244 PKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISV 303
RQT+LFSAT T VKDLA +SLKNP ++V+ + E I +
Sbjct: 393 SHHRQTMLFSATMTDEVKDLASVSLKNPVRIFVNSNTDVAPFLRQEFIRIRPNREGDREA 452
Query: 304 LYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVR 363
+ + L + ++ F+ K+ + + L G+ + LHG Q +R+E F
Sbjct: 453 IVAALLTRTFTDHVMLFTQTKKQAHRMHILLGLM-GLQVGELHGNLSQTQRLEALRRFKD 511
Query: 364 KRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSE 423
++ +L ATD+AARGLD V V+ F P Y+HR GRTAR G ++ ++ E
Sbjct: 512 EQIDILVATDVAARGLDIEGVKTVINFTMPNTIKHYVHRVGRTARAGRAGRSVSLVGEDE 571
Query: 424 KAMVQQLLQ-KKVPVKEIKINPEKLIDVQKKLESI 457
+ M++++++ K PVK + + ++ + K+E +
Sbjct: 572 RKMLKEIVKAAKAPVKARILPQDVILKFRDKIEKM 606
Score = 31.2 bits (69), Expect = 4.4
Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 13/122 (10%)
Query: 722 LHKAKERLQEEDKFDKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSD 781
L K + ++K +K RKK K + +E + + E +EA K ++ K++E+ L +D
Sbjct: 108 LKKKRAATTLDEKIEKV--RKKRKTEDKEAKSGKLEKEKEA-KEGSEPKEQED--LQEND 162
Query: 782 DDDDDDDGFDPSTLPDPDKYRSSEDSDSEDMEN-KISDTKKKQGMKKRSNSEVEDVGPTS 840
++ +D+ + Y S++++ + K+ D KKK+ + + ED
Sbjct: 163 EEGSEDEASETD-------YSSADENILTKADTLKVKDRKKKKKKGQEAGGFFEDASQYD 215
Query: 841 HN 842
N
Sbjct: 216 EN 217
>gi|51094101 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 2
[Homo sapiens]
Length = 881
Score = 201 bits (510), Expect = 3e-51
Identities = 189/704 (26%), Positives = 326/704 (46%), Gaps = 76/704 (10%)
Query: 71 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEA 130
F LS KG+ + Y++ T IQ++TI + L GKDV+ A+TGSGKT FL+P+ E
Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157
Query: 131 LYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERIN- 189
L ++ G LI+SPTRELA QT + +++GK LI+GG ++ + ++
Sbjct: 158 LKT--HSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHE 215
Query: 190 NINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKRQT 249
N +I++ TPGRL+ H+ +S ++ +V DEADR+ +MGFA+ + +I LP QT
Sbjct: 216 NPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQT 274
Query: 250 LLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYSFLR 309
+LFSAT K + + AR L P + + K + L+ ++ + K +VL L
Sbjct: 275 VLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLN--EQLKTSFFLVREDTKAAVLLHLLH 332
Query: 310 SHLK--KKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAA 367
+ ++ +++VF ++ +YL + R VS ++ R +F + +
Sbjct: 333 NVVRPQDQTVVFVATKHHAEYLTELLTTQR--VSCAHIYSALDPTARKINLAKFTLGKCS 390
Query: 368 VLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMV 427
L TD+AARGLD P ++ V+ + P ++HR GR AR G A ++ P E +
Sbjct: 391 TLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYL 450
Query: 428 QQL-------LQKKVPVKE----------IKINPEKLID-----VQKKLESILAQDQDLK 465
L L P+KE + P+ ++D +Q LE+ L + + L
Sbjct: 451 LDLHLFLGRSLTLARPLKEPSGVAGVDGMLGRVPQSVVDEEDSGLQSTLEASL-ELRGLA 509
Query: 466 ERAQRCFVSYVRSVYLMKDKEVFDVSKLPIPEYALSLGLAVAPRVRF----LQKMQKQPT 521
A YVRS + + ++ + + LGL RF LQ+++ +
Sbjct: 510 RVADNAQQQYVRSRPAPSPESIKRAKEMDL----VGLGLHPLFSSRFEEEELQRLRLVDS 565
Query: 522 KELVRSQADKVIEPRAPS--LTNDEVEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTG- 578
+ RS+A + E A S L + + R + ++ Q+G +G + +Q+ G
Sbjct: 566 IKNYRSRA-TIFEINASSRDLCSQVMRAKRQKDRKAIARFQQG---QQGRQEQQEGPVGP 621
Query: 579 ----------NEEQEEEEDDEEEMEEKLAKAKG-SQAPSLPNTSEAQKIKE--------- 618
E+EEEE+ E +E+ ++ G + S PN ++ +E
Sbjct: 622 APSRPALQEKQPEKEEEEEAGESVEDIFSEVVGRKRQRSGPNRGAKRRREEARQRDQEFY 681
Query: 619 VPTQFLDRDEEE------EDADFLKVKRHNVFGLDLKDEKTLQKKEPSKSSIKKKMTKVA 672
+P + D D E E F + V L + + L + +KK V
Sbjct: 682 IPYRPKDFDSERGLSISGEGGAFEQQAAGAVLDLMGDEAQNLTRGRQQLKWDRKKKRFVG 741
Query: 673 EAKKVMKRNFKV--NKKITFTDEGELVQQWPQMQKSAIKDAEED 714
++ + K+ K + I+ + + +L Q+W Q QK +D++E+
Sbjct: 742 QSGQEDKKKIKTESGRYISSSYKRDLYQKWKQKQKIDDRDSDEE 785
>gi|31542656 DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 [Homo
sapiens]
Length = 483
Score = 201 bits (510), Expect = 3e-51
Identities = 144/482 (29%), Positives = 247/482 (51%), Gaps = 28/482 (5%)
Query: 71 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEA 130
F++ LS ++ ++ + T +Q I L+G+D LG AKTGSGKT AF++P+L+
Sbjct: 4 FAELGLSSWLVEQCRQLGLKQPTPVQLGCIPAILEGRDCLGCAKTGSGKTAAFVLPILQK 63
Query: 131 LYRLQWTSTDGLGV--LIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEA-ER 187
L S D G+ L+++PTRELAYQ E R +GK +I+GG D+ +A E
Sbjct: 64 L------SEDPYGIFCLVLTPTRELAYQIAEQFRVLGKPLGLKDCIIVGGMDMVAQALEL 117
Query: 188 INNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFAD---TMNAVIENLP 244
++++ TPGRL H+ + +F ++ LV+DEADR+L+ G D + A++ +P
Sbjct: 118 SRKPHVVIATPGRLADHLRSSNTFSIKKIRFLVMDEADRLLEQGCTDFTVDLEAILAAVP 177
Query: 245 KKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQK---- 300
+RQTLLFSAT T ++++L L+ P + W +A ST L+Q Y++ + K
Sbjct: 178 ARRQTLLFSATLTDTLRELQGLATNQP-FFW-EAQAPVSTVEQLDQRYLLVPEKVKDAYL 235
Query: 301 ISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNE 360
+ ++ F H I+F ++CK Q L + + +ALH +Q R +
Sbjct: 236 VHLIQRFQDEHEDWSIIIFTNTCKTCQILCMMLRKF--SFPTVALHSMMKQKERFAALAK 293
Query: 361 FVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILL 420
F +L ATD+A+RGLD P V V+ + P YIHR GRTAR G+A+ ++
Sbjct: 294 FKSSIYRILIATDVASRGLDIPTVQVVINHNTPGLPKIYIHRVGRTARAGRQGQAITLVT 353
Query: 421 PSEKAMVQQLLQK-KVPVKEIKINPEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSV 479
+ +V + ++ K ++E + +++ + ++ +++ ++ ++K A +
Sbjct: 354 QYDIHLVHAIEEQIKKKLEEFSVEEAEVLQILTQV-NVVRRECEIKLEA----AHFDEKK 408
Query: 480 YLMKDKEVFDVSKLPIPEYALSLGLAVAPRV--RFLQKMQKQPTKELVRSQADKVIEPRA 537
+ K K++ K P E LA + RF +K+++ ++ K PR
Sbjct: 409 EINKRKQLILEGKDPDLEAKRKAELAKIKQKNRRFKEKVEETLKRQKAGRAGHKGRPPRT 468
Query: 538 PS 539
PS
Sbjct: 469 PS 470
>gi|164419743 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 isoform 1
[Homo sapiens]
Length = 882
Score = 201 bits (510), Expect = 3e-51
Identities = 189/704 (26%), Positives = 326/704 (46%), Gaps = 76/704 (10%)
Query: 71 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEA 130
F LS KG+ + Y++ T IQ++TI + L GKDV+ A+TGSGKT FL+P+ E
Sbjct: 98 FQSMGLSYPVFKGIMKKGYKVPTPIQRKTIPVILDGKDVVAMARTGSGKTACFLLPMFER 157
Query: 131 LYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERIN- 189
L ++ G LI+SPTRELA QT + +++GK LI+GG ++ + ++
Sbjct: 158 LKT--HSAQTGARALILSPTRELALQTLKFTKELGKFTGLKTALILGGDRMEDQFAALHE 215
Query: 190 NINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKRQT 249
N +I++ TPGRL+ H+ +S ++ +V DEADR+ +MGFA+ + +I LP QT
Sbjct: 216 NPDIIIATPGRLV-HVAVEMSLKLQSVEYVVFDEADRLFEMGFAEQLQEIIARLPGGHQT 274
Query: 250 LLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYSFLR 309
+LFSAT K + + AR L P + + K + L+ ++ + K +VL L
Sbjct: 275 VLFSATLPKLLVEFARAGLTEPVLIRLDVDTKLN--EQLKTSFFLVREDTKAAVLLHLLH 332
Query: 310 SHLK--KKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAA 367
+ ++ +++VF ++ +YL + R VS ++ R +F + +
Sbjct: 333 NVVRPQDQTVVFVATKHHAEYLTELLTTQR--VSCAHIYSALDPTARKINLAKFTLGKCS 390
Query: 368 VLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMV 427
L TD+AARGLD P ++ V+ + P ++HR GR AR G A ++ P E +
Sbjct: 391 TLIVTDLAARGLDIPLLDNVINYSFPAKGKLFLHRVGRVARAGRSGTAYSLVAPDEIPYL 450
Query: 428 QQL-------LQKKVPVKE----------IKINPEKLID-----VQKKLESILAQDQDLK 465
L L P+KE + P+ ++D +Q LE+ L + + L
Sbjct: 451 LDLHLFLGRSLTLARPLKEPSGVAGVDGMLGRVPQSVVDEEDSGLQSTLEASL-ELRGLA 509
Query: 466 ERAQRCFVSYVRSVYLMKDKEVFDVSKLPIPEYALSLGLAVAPRVRF----LQKMQKQPT 521
A YVRS + + ++ + + LGL RF LQ+++ +
Sbjct: 510 RVADNAQQQYVRSRPAPSPESIKRAKEMDL----VGLGLHPLFSSRFEEEELQRLRLVDS 565
Query: 522 KELVRSQADKVIEPRAPS--LTNDEVEEFRAYFNEKMSILQKGGKRLEGTEHRQDNDTG- 578
+ RS+A + E A S L + + R + ++ Q+G +G + +Q+ G
Sbjct: 566 IKNYRSRA-TIFEINASSRDLCSQVMRAKRQKDRKAIARFQQG---QQGRQEQQEGPVGP 621
Query: 579 ----------NEEQEEEEDDEEEMEEKLAKAKG-SQAPSLPNTSEAQKIKE--------- 618
E+EEEE+ E +E+ ++ G + S PN ++ +E
Sbjct: 622 APSRPALQEKQPEKEEEEEAGESVEDIFSEVVGRKRQRSGPNRGAKRRREEARQRDQEFY 681
Query: 619 VPTQFLDRDEEE------EDADFLKVKRHNVFGLDLKDEKTLQKKEPSKSSIKKKMTKVA 672
+P + D D E E F + V L + + L + +KK V
Sbjct: 682 IPYRPKDFDSERGLSISGEGGAFEQQAAGAVLDLMGDEAQNLTRGRQQLKWDRKKKRFVG 741
Query: 673 EAKKVMKRNFKV--NKKITFTDEGELVQQWPQMQKSAIKDAEED 714
++ + K+ K + I+ + + +L Q+W Q QK +D++E+
Sbjct: 742 QSGQEDKKKIKTESGRYISSSYKRDLYQKWKQKQKIDDRDSDEE 785
>gi|41327776 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 isoform 2
[Homo sapiens]
Length = 406
Score = 198 bits (504), Expect = 2e-50
Identities = 132/416 (31%), Positives = 211/416 (50%), Gaps = 66/416 (15%)
Query: 63 INVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLA 122
+ E F D ++ + + + T+IQ + I LALQG+D++G A+TGSGKT A
Sbjct: 18 VEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGA 77
Query: 123 FLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
F +P+L AL + L L+++PTRELA+Q E +G + + +I+GG D
Sbjct: 78 FALPILNALLE----TPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSM 133
Query: 183 HEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
++ + +I++ TPGRL+ H++ T F+ L+ LV+DEADRIL+M F ++ +++
Sbjct: 134 SQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILK 193
Query: 242 NLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKI 301
+P+ R+T LFSAT TK V+ L R +LKNP V +KY T L+Q YI
Sbjct: 194 VIPRDRKTFLFSATMTKKVQKLQRAALKNP--VKCAVSSKYQTVEKLQQYYI-------- 243
Query: 302 SVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEF 361
F+ S K K R+ N+F
Sbjct: 244 -----FIPSKFKSK--------------------------------------RLGSLNKF 260
Query: 362 VRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLP 421
K ++L ATD+A+RGLD P V+ V+ FD P + YIHR GRTAR G+A+ +
Sbjct: 261 KAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQ 320
Query: 422 SEKAM---VQQLLQKKVP-----VKEIKINPEKLIDVQKKLESILAQDQDLKERAQ 469
+ + ++ L+ KK+P E+ + E++ + Q+ L + + K+R++
Sbjct: 321 YDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEKKKRSR 376
>gi|164664518 DEAD (Asp-Glu-Ala-Asp) box polypeptide 6 [Homo
sapiens]
Length = 483
Score = 185 bits (469), Expect = 2e-46
Identities = 132/456 (28%), Positives = 234/456 (51%), Gaps = 19/456 (4%)
Query: 3 KTANSPGSGARPDPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEK 62
K PG G + N+ K ++ ++Q + + + + +L +
Sbjct: 26 KPTGGPGGGGTQTQ-QQMNQLKNTNTINNGTQQQAQSMTTTIKPGDDWKKTLKLPPKDLR 84
Query: 63 INVNEIT-----RFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGS 117
I +++T F D+ L ++ L G+ E + + IQ+++I +AL G+D+L AK G+
Sbjct: 85 IKTSDVTSTKGNEFEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGT 144
Query: 118 GKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLII- 176
GK+ A+L+P+LE L D + ++I PTRELA Q ++ +V K+ + +
Sbjct: 145 GKSGAYLIPLLERLD----LKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATT 200
Query: 177 GGKDLKHEAERINN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADT 235
GG +L+ + R+++ +++++ TPGR+L + + V+ +QM+VLDEAD++L F
Sbjct: 201 GGTNLRDDIMRLDDTVHVVIATPGRILDLIKKGVA-KVDHVQMIVLDEADKLLSQDFVQI 259
Query: 236 MNAVIENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVC 295
M +I LPK RQ LL+SAT SV+ L+ P + + E+ T + Q Y
Sbjct: 260 MEDIILTLPKNRQILLYSATFPLSVQKFMNSHLQKPYEINLMEEL---TLKGVTQYYAYV 316
Query: 296 ELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRM 355
+QK+ L + +SI+F +S + V+ L + +L G S +H + +Q R
Sbjct: 317 TERQKVHCLNTLFSRLQINQSIIFCNSSQRVELLAKKISQL--GYSCFYIHAKMRQEHRN 374
Query: 356 EVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEA 415
V+++F L TD+ RG+D AVN V+ FD P+ A TY+HR GR+ R+ G A
Sbjct: 375 RVFHDFRNGLCRNLVCTDLFTRGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLA 434
Query: 416 LLILLPSEKAMVQQL-LQKKVPVKEIKINPEKLIDV 450
+ ++ ++ ++ + Q +K I N +K + V
Sbjct: 435 INLITYDDRFNLKSIEEQLGTEIKPIPSNIDKSLYV 470
>gi|21071032 DEAD-box protein abstrakt [Homo sapiens]
Length = 622
Score = 181 bits (460), Expect = 2e-45
Identities = 137/442 (30%), Positives = 215/442 (48%), Gaps = 42/442 (9%)
Query: 43 KPEWQVERESISRLMQNYEKINVN------------EITRFSDFPLSKKTLKGLQEAQYR 90
K W R +S + +E++ I F + L+GL++
Sbjct: 143 KTSWTPPRYVLSMSEERHERVRKKYHILVEGDGIPPPIKSFKEMKFPAAILRGLKKKGIH 202
Query: 91 LVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV----LEALYRLQWTSTDGLGVLI 146
T IQ Q I L G+D++G A TGSGKTL F +PV LE RL ++ +G LI
Sbjct: 203 HPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIMFCLEQEKRLPFSKREGPYGLI 262
Query: 147 ISPTRELAYQTFEVLRKVGK--NHDFS----AGLIIGGKDLKHEAERINN-INILVCTPG 199
I P+RELA QT +L + D S L IGG +K + E I + ++++V TPG
Sbjct: 263 ICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGMSVKEQMETIRHGVHMMVATPG 322
Query: 200 RLLQHMDETVSFHATDL-QMLVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSATQTK 258
RL+ + + + + D+ + L LDEADR++DMGF + + +RQTLLFSAT K
Sbjct: 323 RLMDLLQKKMV--SLDICRYLALDEADRMIDMGFEGDIRTIFSYFKGQRQTLLFSATMPK 380
Query: 259 SVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYSFLRSHLKKKSIV 318
+++ A+ +L P + V S E Y+ +++ ++Y ++
Sbjct: 381 KIQNFAKSALVKPVTINVGRAGAASLDVIQEVEYV----KEEAKMVYLLECLQKTPPPVL 436
Query: 319 FFSSCK-EVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAAR 377
F+ K +V ++ L GV +A+HG + Q R + F + VL ATD+A++
Sbjct: 437 IFAEKKADVDAIHEYL--LLKGVEAVAIHGGKDQEERTKAIEAFREGKKDVLVATDVASK 494
Query: 378 GLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLIL--------LPSEKAMVQQ 429
GLDFPA+ V+ +D PE+ Y+HR GRT R G A + L KA++ +
Sbjct: 495 GLDFPAIQHVINYDMPEEIENYVHRIGRTGRSGNTGIATTFINKACDESVLMDLKALLLE 554
Query: 430 LLQKKVPVKEI-KINPEKLIDV 450
QK PV ++ E ++D+
Sbjct: 555 AKQKVPPVLQVLHCGDESMLDI 576
>gi|45446747 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 180 bits (457), Expect = 4e-45
Identities = 124/376 (32%), Positives = 199/376 (52%), Gaps = 29/376 (7%)
Query: 71 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVL-E 129
F+ F ++ + +++++Y T IQ Q + +AL G+D++G AKTGSGKT AF+ P+L
Sbjct: 255 FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIH 314
Query: 130 ALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERI- 188
+ + + DG +I+ PTREL Q ++ GK ++ + + GG + +A+ +
Sbjct: 315 IMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQ 374
Query: 189 NNINILVCTPGRLLQHMDETVSFHATDLQ---MLVLDEADRILDMGFADTMNAVIENLPK 245
I+VCTPGRL+ H V AT+LQ LV DEADR+ DMGF + ++ ++
Sbjct: 375 EGAEIVVCTPGRLIDH----VKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRP 430
Query: 246 KRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLY 305
RQTLLFSAT K ++ LAR L +P V + + + T Q + +L+
Sbjct: 431 DRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVT-----------QIVEILH 479
Query: 306 S--FLRSHLKKKSIVFFSSCKEVQYLYR-------VFCRLRPGVSILALHGRQQQMRRME 356
S + L ++ + F SS + ++ + + G ++ LHG Q R +
Sbjct: 480 SGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNK 539
Query: 357 VYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEAL 416
V ++F +K VL ATD+AARGLD P++ V+ +D D +T+ HR GRT R E G A
Sbjct: 540 VISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAY 599
Query: 417 LILLPSEKAMVQQLLQ 432
+L P + L++
Sbjct: 600 TLLTPKDSNFAGDLVR 615
>gi|45446743 DEAD box polypeptide 42 protein [Homo sapiens]
Length = 938
Score = 180 bits (457), Expect = 4e-45
Identities = 124/376 (32%), Positives = 199/376 (52%), Gaps = 29/376 (7%)
Query: 71 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVL-E 129
F+ F ++ + +++++Y T IQ Q + +AL G+D++G AKTGSGKT AF+ P+L
Sbjct: 255 FAHFGFDEQLMHQIRKSEYTQPTPIQCQGVPVALSGRDMIGIAKTGSGKTAAFIWPMLIH 314
Query: 130 ALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERI- 188
+ + + DG +I+ PTREL Q ++ GK ++ + + GG + +A+ +
Sbjct: 315 IMDQKELEPGDGPIAVIVCPTRELCQQIHAECKRFGKAYNLRSVAVYGGGSMWEQAKALQ 374
Query: 189 NNINILVCTPGRLLQHMDETVSFHATDLQ---MLVLDEADRILDMGFADTMNAVIENLPK 245
I+VCTPGRL+ H V AT+LQ LV DEADR+ DMGF + ++ ++
Sbjct: 375 EGAEIVVCTPGRLIDH----VKKKATNLQRVSYLVFDEADRMFDMGFEYQVRSIASHVRP 430
Query: 246 KRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLY 305
RQTLLFSAT K ++ LAR L +P V + + + T Q + +L+
Sbjct: 431 DRQTLLFSATFRKKIEKLARDILIDPIRVVQGDIGEANEDVT-----------QIVEILH 479
Query: 306 S--FLRSHLKKKSIVFFSSCKEVQYLYR-------VFCRLRPGVSILALHGRQQQMRRME 356
S + L ++ + F SS + ++ + + G ++ LHG Q R +
Sbjct: 480 SGPSKWNWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQEGHNLGLLHGDMDQSERNK 539
Query: 357 VYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEAL 416
V ++F +K VL ATD+AARGLD P++ V+ +D D +T+ HR GRT R E G A
Sbjct: 540 VISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDIDTHTHRIGRTGRAGEKGVAY 599
Query: 417 LILLPSEKAMVQQLLQ 432
+L P + L++
Sbjct: 600 TLLTPKDSNFAGDLVR 615
>gi|13129006 nucleolar protein GU2 [Homo sapiens]
Length = 737
Score = 177 bits (450), Expect = 3e-44
Identities = 137/442 (30%), Positives = 222/442 (50%), Gaps = 31/442 (7%)
Query: 15 DPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEKINVNEITR---- 70
D FNR + S +++ E++ + + +S L + K + N++
Sbjct: 73 DTEEGFNRLSDEFSKSHKSRRKDLPNGDIDEYEKKSKRVSSLDTSTHKSSDNKLEETLTR 132
Query: 71 ------FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFL 124
FS+FP+S++T+K L+ + IQ +T G +GKD++ A+TG+GKT +F
Sbjct: 133 EQKEGAFSNFPISEETIKLLKGRGVTYLFPIQVKTFGPVYEGKDLIAQARTGTGKTFSFA 192
Query: 125 VPVLEALYRLQWTSTDGLG--VLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
+P++E L R Q T VL+++PTRELA Q + + + + S GG +
Sbjct: 193 IPLIERLQRNQETIKKSRSPKVLVLAPTRELANQVAKDFKDITRK--LSVACFYGGTSYQ 250
Query: 183 HEAERINN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
+ I N I+ILV TPGR+ H+ ++ + L+ +VLDE D++LD+GFA+ + +I
Sbjct: 251 SQINHIRNGIDILVGTPGRIKDHL-QSGRLDLSKLRHVVLDEVDQMLDLGFAEQVEDIIH 309
Query: 242 NLPK-----KRQTLLFSATQTKSVKDLARLSLKNP-EYVWVHEKAKYSTPATLEQNYIVC 295
K QTLLFSAT + V +A+ +K+ E V + K T+E I C
Sbjct: 310 ESYKTDSEDNPQTLLFSATCPQWVYKVAKKYMKSRYEQVDLVGKMTQKAATTVEHLAIQC 369
Query: 296 ELQQKISVLYSFLR--SHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILA--LHGRQQQ 351
Q+ +V+ L+ S + ++I+F + K V + + P + A LHG Q
Sbjct: 370 HWSQRPAVIGDVLQVYSGSEGRAIIFCETKKNVTEM-----AMNPHIKQNAQCLHGDIAQ 424
Query: 352 MRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKE 411
+R F VL AT++AARGLD P V+ V+Q P+D +YIHR+GRT R
Sbjct: 425 SQREITLKGFREGSFKVLVATNVAARGLDIPEVDLVIQSSPPQDVESYIHRSGRTGRAGR 484
Query: 412 DGEALLILLPSEKAMVQQLLQK 433
G + P E+ ++ + QK
Sbjct: 485 TGICICFYQPRERGQLRYVEQK 506
>gi|148613856 DEAD box polypeptide 17 isoform 3 [Homo sapiens]
Length = 731
Score = 176 bits (445), Expect = 1e-43
Identities = 125/373 (33%), Positives = 190/373 (50%), Gaps = 12/373 (3%)
Query: 84 LQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTST-DGL 142
L + + T IQ Q LAL G+D++G A+TGSGKTLA+L+P + + + DG
Sbjct: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245
Query: 143 GVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINN-INILVCTPGRL 201
L+++PTRELA Q +V GK + I GG + + + I + TPGRL
Sbjct: 246 ICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 305
Query: 202 LQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSATQTKSVK 261
+ + E+ + LVLDEADR+LDMGF + +++ + RQTL++SAT K V+
Sbjct: 306 IDFL-ESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVR 364
Query: 262 DLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVC---ELQQKISVLYSFLRSHLKKKSIV 318
LA L++ + V + S + Q VC E K+ L + + + K+I+
Sbjct: 365 QLAEDFLRDYTQINVGN-LELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTII 423
Query: 319 FFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARG 378
F + + L R R G + +HG + Q R V NEF +A +L ATD+A+RG
Sbjct: 424 FVETKRRCDDLTRRM--RRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
Query: 379 LDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVK 438
LD V +V+ +D P + Y+HR GRTAR G A P ++L+ K +
Sbjct: 482 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELI-KVLEEA 540
Query: 439 EIKINPE--KLID 449
INP+ +L+D
Sbjct: 541 NQAINPKLMQLVD 553
>gi|38201710 DEAD box polypeptide 17 isoform 1 [Homo sapiens]
Length = 729
Score = 176 bits (445), Expect = 1e-43
Identities = 125/373 (33%), Positives = 190/373 (50%), Gaps = 12/373 (3%)
Query: 84 LQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTST-DGL 142
L + + T IQ Q LAL G+D++G A+TGSGKTLA+L+P + + + DG
Sbjct: 186 LMDQHFTEPTPIQCQGFPLALSGRDMVGIAQTGSGKTLAYLLPAIVHINHQPYLERGDGP 245
Query: 143 GVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINN-INILVCTPGRL 201
L+++PTRELA Q +V GK + I GG + + + I + TPGRL
Sbjct: 246 ICLVLAPTRELAQQVQQVADDYGKCSRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRL 305
Query: 202 LQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSATQTKSVK 261
+ + E+ + LVLDEADR+LDMGF + +++ + RQTL++SAT K V+
Sbjct: 306 IDFL-ESGKTNLRRCTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVR 364
Query: 262 DLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVC---ELQQKISVLYSFLRSHLKKKSIV 318
LA L++ + V + S + Q VC E K+ L + + + K+I+
Sbjct: 365 QLAEDFLRDYTQINVGN-LELSANHNILQIVDVCMESEKDHKLIQLMEEIMAEKENKTII 423
Query: 319 FFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARG 378
F + + L R R G + +HG + Q R V NEF +A +L ATD+A+RG
Sbjct: 424 FVETKRRCDDLTRRM--RRDGWPAMCIHGDKSQPERDWVLNEFRSGKAPILIATDVASRG 481
Query: 379 LDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVK 438
LD V +V+ +D P + Y+HR GRTAR G A P ++L+ K +
Sbjct: 482 LDVEDVKFVINYDYPNSSEDYVHRIGRTARSTNKGTAYTFFTPGNLKQARELI-KVLEEA 540
Query: 439 EIKINPE--KLID 449
INP+ +L+D
Sbjct: 541 NQAINPKLMQLVD 553
>gi|50659095 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 [Homo
sapiens]
Length = 783
Score = 176 bits (445), Expect = 1e-43
Identities = 142/435 (32%), Positives = 217/435 (49%), Gaps = 22/435 (5%)
Query: 14 PDPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYE---KINVNEIT- 69
P P + + K+ + + K +L+ PE + N E +I V +
Sbjct: 128 PKP-KKMKKEKEMNGETREKSPKLKNGFPHPEPDCNPSEAASEESNSEIEQEIPVEQKEG 186
Query: 70 RFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLE 129
FS+FP+S++T+K L+ + IQ +T GKD++ A+TG+GKT +F +P++E
Sbjct: 187 AFSNFPISEETIKLLKGRGVTFLFPIQAKTFHHVYSGKDLIAQARTGTGKTFSFAIPLIE 246
Query: 130 ALYRLQWTSTDGLG--VLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAER 187
L+ G VL+++PTRELA Q + + K S GG + ER
Sbjct: 247 KLHGELQDRKRGRAPQVLVLAPTRELANQVSKDFSDITKK--LSVACFYGGTPYGGQFER 304
Query: 188 INN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKK 246
+ N I+ILV TPGR+ H+ + T L+ +VLDE D++LDMGFAD + ++ KK
Sbjct: 305 MRNGIDILVGTPGRIKDHI-QNGKLDLTKLKHVVLDEVDQMLDMGFADQVEEILSVAYKK 363
Query: 247 R-----QTLLFSATQTKSVKDLARLSLKNP-EYVWVHEKAKYSTPATLEQNYIVCELQQK 300
QTLLFSAT V ++A+ +K+ E V + K T T+E I C Q+
Sbjct: 364 DSEDNPQTLLFSATCPHWVFNVAKKYMKSTYEQVDLIGKKTQKTAITVEHLAIKCHWTQR 423
Query: 301 ISVLYSFLR--SHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEVY 358
+V+ +R S + ++I+F + KE Q L + + S LHG Q +R
Sbjct: 424 AAVIGDVIRVYSGHQGRTIIFCETKKEAQELSQNSAIKQDAQS---LHGDIPQKQREITL 480
Query: 359 NEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALLI 418
F VL AT++AARGLD P V+ V+Q P+D +YIHR+GRT R G +
Sbjct: 481 KGFRNGSFGVLVATNVAARGLDIPEVDLVIQSSPPKDVESYIHRSGRTGRAGRTGVCICF 540
Query: 419 LLPSEKAMVQQLLQK 433
E+ + Q+ QK
Sbjct: 541 YQHKEEYQLVQVEQK 555
Score = 31.6 bits (70), Expect = 3.4
Identities = 40/193 (20%), Positives = 83/193 (43%), Gaps = 26/193 (13%)
Query: 554 EKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEE-----MEEKLAKAKGSQAPSLP 608
E + ++KG + TE ++ + ++ EE +EEE ++ KA+ S+
Sbjct: 12 ESDTAMKKGETLRKQTEEKEKKEKPKSDKTEEIAEEEETVFPKAKQVKKKAEPSEVDMNS 71
Query: 609 NTSEAQKIKEVPTQFLDRDEEEEDADFLKVKRHNVFG--LDLKDEKTLQKKEPSKSSIKK 666
S+ K KE P+Q ++ L+ K+ + + K +K + +EPS+ I
Sbjct: 72 PKSKKAKKKEEPSQ----NDISPKTKSLRKKKEPIEKKVVSSKTKKVTKNEEPSEEEID- 126
Query: 667 KMTKVAEAKKVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDDDTGGINLHKAK 726
A K MK+ ++N GE ++ P++ K+ E D + ++
Sbjct: 127 -----APKPKKMKKEKEMN--------GETREKSPKL-KNGFPHPEPDCNPSEAASEESN 172
Query: 727 ERLQEEDKFDKEE 739
+++E +++E
Sbjct: 173 SEIEQEIPVEQKE 185
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 174 bits (442), Expect = 2e-43
Identities = 120/347 (34%), Positives = 183/347 (52%), Gaps = 13/347 (3%)
Query: 76 LSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQ 135
+S K L L++ Y T IQ Q I + G+D++G AKTGSGKT+AFL+P+ + Q
Sbjct: 379 ISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGSGKTIAFLLPMFRHIMD-Q 437
Query: 136 WTSTDGLG--VLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHE-AERINNIN 192
+ +G G +I++PTRELA Q + +K K + GG + + AE
Sbjct: 438 RSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVYGGTGISEQIAELKRGAE 497
Query: 193 ILVCTPGRLLQHMDETVSFHATDLQML---VLDEADRILDMGFADTMNAVIENLPKKRQT 249
I+VCTPGR++ + S T+L+ + VLDEADR+ DMGF + +++N+ RQT
Sbjct: 498 IIVCTPGRMIDMLAAN-SGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIVDNVRPDRQT 556
Query: 250 LLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYSFLR 309
++FSAT ++++ LAR L P V V ++ + +EQ IV E ++K L L
Sbjct: 557 VMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSD--VEQQVIVIEEEKKFLKLLELLG 614
Query: 310 SHLKKKSIVFFSSCKE-VQYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAV 368
+ + S++ F +E L + +R ++LHG Q R + N+F +
Sbjct: 615 HYQESGSVIIFVDKQEHADGLLKDL--MRASYPCMSLHGGIDQYDRDSIINDFKNGTCKL 672
Query: 369 LFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEA 415
L AT +AARGLD + V+ + CP Y+HRAGRT R G A
Sbjct: 673 LVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYA 719
Score = 40.0 bits (92), Expect = 0.009
Identities = 59/299 (19%), Positives = 112/299 (37%), Gaps = 48/299 (16%)
Query: 547 EFRAYFNEKMSILQKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEEMEEKLAKAKGSQAPS 606
E R Y S + G + + + + G++ + D + E ++ K
Sbjct: 4 ESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS--- 60
Query: 607 LPNTSEAQKIKEVPTQFLDRDEEEEDADFLKVKRHNVFGLDLKDEKTLQKKEPSKSSIKK 666
+ + ++++ ++ DR E R D + ++ + S+SS
Sbjct: 61 --RSRDRKRLRRSRSRERDRSRE----------RRRSRSRDRRRSRSRSRGRRSRSSSPG 108
Query: 667 KMTKVAEAKKVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDD---DTGGINLH 723
+K E + K TD GE +K KD +ED+ D G + +
Sbjct: 109 NKSKKTENRSRSKEK---------TDGGE-----SSKEKKKDKDDKEDEKEKDAGNFDQN 154
Query: 724 KAKERLQEEDKFDKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSDDD 783
K +E +++ +++++ E+R K E E K + K ++ WS +D
Sbjct: 155 KLEEEMRKR--------KERVEKWREEQRKKAMENIGELKKEIEEMKQGKK----WSLED 202
Query: 784 DDDDDGFDPSTLPDPDKYRSSEDSDSED-MENKISDTKKKQGMK--KRSNSEVEDVGPT 839
DDDD+ DP+ E+ D D ++ + KK M+ K + GPT
Sbjct: 203 DDDDED-DPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVKGGGGNEKKSGPT 260
>gi|209862869 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 3
[Homo sapiens]
Length = 724
Score = 174 bits (440), Expect = 4e-43
Identities = 122/376 (32%), Positives = 192/376 (51%), Gaps = 15/376 (3%)
Query: 68 ITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV 127
I F + L + + +A Y +T +QK +I + L G+D++ A+TGSGKT AFL+P+
Sbjct: 287 ILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPI 346
Query: 128 L-----EALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
L + + ++ +I++PTREL Q + RK A +I GG L
Sbjct: 347 LAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLG 406
Query: 183 HEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
H +I NIL TPGRL+ + + ++ LVLDEADR+LDMGF M +I
Sbjct: 407 HSIRQIVQGCNILCATPGRLMDIIGKE-KIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 465
Query: 242 --NLPKK--RQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCEL 297
+P K RQTL+FSAT + ++ LA LK+ Y++V ++Q +
Sbjct: 466 CPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKS-NYLFVAVGQVGGACRDVQQTVLQVGQ 524
Query: 298 QQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEV 357
K L LR+ ++++VF + K+ ++ C+ + +S ++HG ++Q R +
Sbjct: 525 FSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEK--ISTTSIHGDREQREREQA 582
Query: 358 YNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALL 417
+F + VL AT +AARGLD V V+ FD P + Y+HR GRT R G A+
Sbjct: 583 LGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642
Query: 418 IL-LPSEKAMVQQLLQ 432
L S+ + Q L++
Sbjct: 643 FFDLESDNHLAQPLVK 658
>gi|13518015 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 1
[Homo sapiens]
Length = 724
Score = 174 bits (440), Expect = 4e-43
Identities = 122/376 (32%), Positives = 192/376 (51%), Gaps = 15/376 (3%)
Query: 68 ITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV 127
I F + L + + +A Y +T +QK +I + L G+D++ A+TGSGKT AFL+P+
Sbjct: 287 ILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPI 346
Query: 128 L-----EALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
L + + ++ +I++PTREL Q + RK A +I GG L
Sbjct: 347 LAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLG 406
Query: 183 HEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
H +I NIL TPGRL+ + + ++ LVLDEADR+LDMGF M +I
Sbjct: 407 HSIRQIVQGCNILCATPGRLMDIIGKE-KIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 465
Query: 242 --NLPKK--RQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCEL 297
+P K RQTL+FSAT + ++ LA LK+ Y++V ++Q +
Sbjct: 466 CPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKS-NYLFVAVGQVGGACRDVQQTVLQVGQ 524
Query: 298 QQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEV 357
K L LR+ ++++VF + K+ ++ C+ + +S ++HG ++Q R +
Sbjct: 525 FSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEK--ISTTSIHGDREQREREQA 582
Query: 358 YNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALL 417
+F + VL AT +AARGLD V V+ FD P + Y+HR GRT R G A+
Sbjct: 583 LGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 642
Query: 418 IL-LPSEKAMVQQLLQ 432
L S+ + Q L++
Sbjct: 643 FFDLESDNHLAQPLVK 658
>gi|216548263 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 isoform 2
[Homo sapiens]
Length = 690
Score = 174 bits (440), Expect = 4e-43
Identities = 122/376 (32%), Positives = 192/376 (51%), Gaps = 15/376 (3%)
Query: 68 ITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV 127
I F + L + + +A Y +T +QK +I + L G+D++ A+TGSGKT AFL+P+
Sbjct: 253 ILTFEEANLCQTLNNNIAKAGYTKLTPVQKYSIPIILAGRDLMACAQTGSGKTAAFLLPI 312
Query: 128 L-----EALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLK 182
L + + ++ +I++PTREL Q + RK A +I GG L
Sbjct: 313 LAHMMHDGITASRFKELQEPECIIVAPTRELVNQIYLEARKFSFGTCVRAVVIYGGTQLG 372
Query: 183 HEAERI-NNINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIE 241
H +I NIL TPGRL+ + + ++ LVLDEADR+LDMGF M +I
Sbjct: 373 HSIRQIVQGCNILCATPGRLMDIIGKE-KIGLKQIKYLVLDEADRMLDMGFGPEMKKLIS 431
Query: 242 --NLPKK--RQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQNYIVCEL 297
+P K RQTL+FSAT + ++ LA LK+ Y++V ++Q +
Sbjct: 432 CPGMPSKEQRQTLMFSATFPEEIQRLAAEFLKS-NYLFVAVGQVGGACRDVQQTVLQVGQ 490
Query: 298 QQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRMEV 357
K L LR+ ++++VF + K+ ++ C+ + +S ++HG ++Q R +
Sbjct: 491 FSKREKLVEILRNIGDERTMVFVETKKKADFIATFLCQEK--ISTTSIHGDREQREREQA 548
Query: 358 YNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEALL 417
+F + VL AT +AARGLD V V+ FD P + Y+HR GRT R G A+
Sbjct: 549 LGDFRFGKCPVLVATSVAARGLDIENVQHVINFDLPSTIDEYVHRIGRTGRCGNTGRAIS 608
Query: 418 IL-LPSEKAMVQQLLQ 432
L S+ + Q L++
Sbjct: 609 FFDLESDNHLAQPLVK 624
>gi|4758138 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 [Homo sapiens]
Length = 614
Score = 173 bits (439), Expect = 5e-43
Identities = 124/361 (34%), Positives = 186/361 (51%), Gaps = 12/361 (3%)
Query: 93 TEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTST-DGLGVLIISPTR 151
T IQ Q +AL G D++G A+TGSGKTL++L+P + + + DG L+++PTR
Sbjct: 118 TAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTR 177
Query: 152 ELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERINN-INILVCTPGRLLQHMDETVS 210
ELA Q +V + + + I GG + + + I + TPGRL+ + E
Sbjct: 178 ELAQQVQQVAAEYCRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPGRLIDFL-ECGK 236
Query: 211 FHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSATQTKSVKDLARLSLKN 270
+ LVLDEADR+LDMGF + +++ + RQTL++SAT K V+ LA LK
Sbjct: 237 TNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLK- 295
Query: 271 PEYVWVHEKA-KYSTPATLEQNYIVC---ELQQKISVLYSFLRSHLKKKSIVFFSSCKEV 326
+Y+ ++ A + S + Q VC E +K+ L + S + K+IVF + +
Sbjct: 296 -DYIHINIGALELSANHNILQIVDVCHDVEKDEKLIRLMEEIMSEKENKTIVFVETKRRC 354
Query: 327 QYLYRVFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNW 386
L R R G + +HG + Q R V NEF +A +L ATD+A+RGLD V +
Sbjct: 355 DELTRKM--RRDGWPAMGIHGDKSQQERDWVLNEFKHGKAPILIATDVASRGLDVEDVKF 412
Query: 387 VLQFDCPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVKEIKINPEK 446
V+ +D P + YIHR GRTAR + G A P+ V L+ + INP+
Sbjct: 413 VINYDYPNSSEDYIHRIGRTARSTKTGTAYTFFTPNNIKQVSDLISVLREANQ-AINPKL 471
Query: 447 L 447
L
Sbjct: 472 L 472
>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
sapiens]
Length = 820
Score = 171 bits (432), Expect = 4e-42
Identities = 137/471 (29%), Positives = 219/471 (46%), Gaps = 42/471 (8%)
Query: 24 KKKHSHRQNKKKQLRKQLKKPEWQVERESISRLMQNYEKINVNEITRFSDFPLSKKTLKG 83
K++ R +K+L + + +W++ RE S + KI N I + D L L+
Sbjct: 349 KQRWDDRHWSQKKLDEMTDR-DWRIFREDYS-ITTKGGKIP-NPIRSWKDSSLPPHILEV 405
Query: 84 LQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWT-----S 138
+ + Y+ T IQ+Q I + LQ +D++G A+TGSGKT AFL+P+L + L S
Sbjct: 406 IDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDRIEES 465
Query: 139 TDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERIN-NINILVCT 197
G +I++PTRELA Q E K GK +IGG + + R+ I++ T
Sbjct: 466 DQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEIVIAT 525
Query: 198 PGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLP------------- 244
PGRL+ ++ + +VLDEADR++DMGF + ++E++P
Sbjct: 526 PGRLIDVLENRYLV-LSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDEAED 584
Query: 245 -------------KKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTPATLEQN 291
K RQT++F+AT +V+ LAR L+ P V++ K +EQ
Sbjct: 585 PEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGK--PHERVEQK 642
Query: 292 YIVCELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQ 351
+ +K L + L I+F + K L + ++ G + LHG + Q
Sbjct: 643 VFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKM--GYNACTLHGGKGQ 700
Query: 352 MRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKE 411
+R + +L ATD+A RG+D V+ V+ +D ++ YIHR GRT R +
Sbjct: 701 EQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAGK 760
Query: 412 DGEALLILLPSEKAMVQQLLQK--KVPVKEIKINPEKLIDVQKKLESILAQ 460
G A+ L + A+ +L Q + PV D Q K +IL +
Sbjct: 761 SGVAITFLTKEDSAVFYELKQAILESPVSSCPPELANHPDAQHKPGTILTK 811
Score = 43.9 bits (102), Expect = 7e-04
Identities = 48/226 (21%), Positives = 93/226 (41%), Gaps = 35/226 (15%)
Query: 560 QKGGKRLEGTEHRQDNDTGNEEQEEEEDDEEEMEEK--------LAKAKGSQAPSLPNTS 611
++GG R + + +E E D E + +K + K + SL +
Sbjct: 53 RRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSL-SPG 111
Query: 612 EAQKIKEVPTQFLDRDEEEEDADFLKVKRHNVFGLDLKD--------------EKTLQKK 657
+ K + +DEE+E D K+ L L++ K L K
Sbjct: 112 RGKDFKSRKDRDSKKDEEDEHGD----KKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKA 167
Query: 658 EPSKSSIKKKMTKVAEAKKVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDDDT 717
E ++K++ +V E +++++ K K+ F D G + + PQ ++ + + +T
Sbjct: 168 EREAEALKRRQQEVEERQRMLEEERKKRKQ--FQDLGRKMLEDPQERERRERRERMERET 225
Query: 718 GGINLHKAKERLQEE-DKFD-----KEEYRKKIKAKHREKRLKERE 757
G + +++++EE DK KE Y IK + R + L +R+
Sbjct: 226 NGNEDEEGRQKIREEKDKSKELHAIKERYLGGIKKRRRTRHLNDRK 271
Score = 42.4 bits (98), Expect = 0.002
Identities = 43/233 (18%), Positives = 97/233 (41%), Gaps = 37/233 (15%)
Query: 570 EHRQDNDTGNEEQEEEEDDEEEMEEKLAKAKGSQAPSLPNTSEAQKIKEVPTQFLDRDEE 629
E +D + +++ + D + +K K + S +P +++K ++ +DEE
Sbjct: 76 ERERDKERDRNKKDRDRDKDGHRRDKDRK-RSSLSPGRGKDFKSRKDRDSK-----KDEE 129
Query: 630 EEDADFLKVKRHNVFGLDLKD--------------EKTLQKKEPSKSSIKKKMTKVAEAK 675
+E D K+ L L++ K L K E ++K++ +V E +
Sbjct: 130 DEHGD----KKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAEALKRRQQEVEERQ 185
Query: 676 KVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDDDTGGINLHKAKERLQEEDKF 735
++++ K K+ F D G + + PQ ++ + + +T G + +++++EE
Sbjct: 186 RMLEEERKKRKQ--FQDLGRKMLEDPQERERRERRERMERETNGNEDEEGRQKIREEKDK 243
Query: 736 DKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSDDDDDDDD 788
KE + +KER +R+ + ++ + +W +D D
Sbjct: 244 SKELHA-----------IKERYLGGIKKRRRTRHLNDRKFVFEWDASEDTSID 285
Score = 38.1 bits (87), Expect = 0.036
Identities = 32/143 (22%), Positives = 64/143 (44%), Gaps = 6/143 (4%)
Query: 723 HKAKERLQEEDKFDKEEYRKKIKAKHREKRLKEREARREANKRQAKAKDEEEAFLDWSDD 782
HK +ER +E D+ K+ R + K HR + ++R + + K++ + ++ D D+
Sbjct: 74 HKERERDKERDRNKKD--RDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDE 131
Query: 783 DDDDDDGFDPSTLPDPDKYRSSEDSDSEDMENKISDTKKKQGMKKRSNSEVEDVGPTSHN 842
D P +L + + +E+ ++E +S +++ KR EVE+
Sbjct: 132 HGDKKPKAQPLSLEELLAKKKAEE-EAEAKPKFLSKAEREAEALKRRQQEVEERQRMLEE 190
Query: 843 RKKARWDTLEPLDTGLSLAEDEE 865
+K R + D G + ED +
Sbjct: 191 ERKKR---KQFQDLGRKMLEDPQ 210
Score = 35.4 bits (80), Expect = 0.23
Identities = 40/225 (17%), Positives = 91/225 (40%), Gaps = 27/225 (12%)
Query: 564 KRLEGTEHRQDNDTGNEEQEEEEDDEEEMEEKLAKAKGSQAPSLPNTSEAQKIKEVPTQF 623
KR + +D D + ++ ++ S++ S ++E ++ + +
Sbjct: 21 KRSRTPDRERDRDRDRKSSPSKDRKRHRSRDRRRGGSRSRSRSRSKSAERERRHKERERD 80
Query: 624 LDRDEEEEDADFLKV--------KRHNVFGLDLKDEKTLQKKEPSKSSIKKKMTKVAEAK 675
+RD ++D D K KR ++ KD K+ + ++ K + K +A+
Sbjct: 81 KERDRNKKDRDRDKDGHRRDKDRKRSSLSPGRGKDFKSRKDRDSKKDEEDEHGDKKPKAQ 140
Query: 676 KVMKRNFKVNKKITFTDEGELVQQWPQMQKSAIKDAEEDDDTGGINLHKAKERLQEEDKF 735
+ KK E + P+ A ++AE L + ++ ++E +
Sbjct: 141 PLSLEELLAKKKAEEEAEAK-----PKFLSKAEREAEA--------LKRRQQEVEERQRM 187
Query: 736 DKEEYRKKIKAKHREKRL------KEREARREANKRQAKAKDEEE 774
+EE +K+ + + +++ +ER RRE +R+ ++EE
Sbjct: 188 LEEERKKRKQFQDLGRKMLEDPQERERRERRERMERETNGNEDEE 232
>gi|222352149 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 [Homo
sapiens]
Length = 648
Score = 170 bits (430), Expect = 6e-42
Identities = 137/492 (27%), Positives = 247/492 (50%), Gaps = 32/492 (6%)
Query: 2 GKTANSPGSGARP----DPVRSFN-RWKK----------KHSHRQNKKKQLRKQLKKPEW 46
G T N+ +G RP D +R +W+K K+ ++++ +++ W
Sbjct: 157 GSTDNNVVAGDRPLIDWDQIREEGLKWQKTKWADLPPIKKNFYKESTATSAMSKVEADSW 216
Query: 47 QVERESIS--RLMQNYEKINVNEITRFSD-FPLSKKTLKGLQEAQYRLVTEIQKQTIGLA 103
+ E +I+ L ++ N F D F + ++ +++A ++ T IQ Q +
Sbjct: 217 RKENFNITWDDLKDGEKRPIPNPTCTFDDAFQCYPEVMENIKKAGFQKPTPIQSQAWPIV 276
Query: 104 LQGKDVLGAAKTGSGKTLAFLVP-----VLEALYRLQWTSTDGLGVLIISPTRELAYQTF 158
LQG D++G A+TG+GKTL +L+P VL+ + Q G+L+++PTRELA Q
Sbjct: 277 LQGIDLIGVAQTGTGKTLCYLMPGFIHLVLQPSLKGQRNRP---GMLVLTPTRELALQVE 333
Query: 159 EVLRKVGKNHDFSAGLIIGGKDLKHEAERINNINILVCTPGRLLQHMDETVSFHATDLQM 218
K S + GG + E ++I++ TPGRL + + + ++
Sbjct: 334 GECCKYSYKGLRSVCVYGGGNRDEQIEELKKGVDIIIATPGRL-NDLQMSNFVNLKNITY 392
Query: 219 LVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHE 278
LVLDEAD++LDMGF + ++ ++ RQT++ SAT SV LA+ LK P V+V
Sbjct: 393 LVLDEADKMLDMGFEPQIMKILLDVRPDRQTVMTSATWPHSVHRLAQSYLKEPMIVYVGT 452
Query: 279 KAKYSTPATLEQNYIVCELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRP 338
+ ++++QN IV ++K S + +FL+S ++ F S K V + +
Sbjct: 453 LDLVAV-SSVKQNIIVTTEEEKWSHMQTFLQSMSSTDKVIVFVSRKAVAD-HLSSDLILG 510
Query: 339 GVSILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANT 398
+S+ +LHG ++Q R + F + +L ATD+A+RGLD V V FD P +
Sbjct: 511 NISVESLHGDREQRDREKALENFKTGKVRILIATDLASRGLDVHDVTHVYNFDFPRNIEE 570
Query: 399 YIHRAGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVKEIKINPEKLIDVQKKLESIL 458
Y+HR GRT R G ++ L ++ + +L+ + + + PE+L+ + ++ ++
Sbjct: 571 YVHRIGRTGRAGRTGVSITTLTRNDWRVASELI--NILERANQSIPEELVSMAERFKA-H 627
Query: 459 AQDQDLKERAQR 470
Q ++++ + +R
Sbjct: 628 QQKREMERKMER 639
>gi|87196351 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3 [Homo
sapiens]
Length = 662
Score = 166 bits (421), Expect = 7e-41
Identities = 125/397 (31%), Positives = 187/397 (47%), Gaps = 35/397 (8%)
Query: 68 ITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV 127
I FSD + + + ++ +Y T +QK I + + +D++ A+TGSGKT AFL+P+
Sbjct: 179 IESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPI 238
Query: 128 LEALYRLQWTSTDGLGV--------------------LIISPTRELAYQTFEVLRKVGKN 167
L +Y +DG G L+++PTRELA Q +E RK
Sbjct: 239 LSQIY------SDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYR 292
Query: 168 HDFSAGLIIGGKDLKHEAERINN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADR 226
++ GG D+ + + ++LV TPGRL+ M E + LVLDEADR
Sbjct: 293 SRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMM-ERGKIGLDFCKYLVLDEADR 351
Query: 227 ILDMGFADTMNAVIEN--LPKK--RQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKY 282
+LDMGF + ++E +P K R T++FSAT K ++ LAR L EY+++
Sbjct: 352 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD--EYIFLAVGRVG 409
Query: 283 STPATLEQNYIVCELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSI 342
ST + Q + E K S L L + K + F K+ F G +
Sbjct: 410 STSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFL-YHEGYAC 468
Query: 343 LALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHR 402
++HG + Q R E ++F ++ +L AT +AARGLD V V+ FD P D Y+HR
Sbjct: 469 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHR 528
Query: 403 AGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVKE 439
GRT R G A + + LL V K+
Sbjct: 529 IGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQ 565
>gi|20336298 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 isoform 2
[Homo sapiens]
Length = 585
Score = 166 bits (421), Expect = 7e-41
Identities = 112/332 (33%), Positives = 180/332 (54%), Gaps = 51/332 (15%)
Query: 92 VTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWT--STDGLGVLIISP 149
+T +QKQ+I + L+G+D L ++TGSGKTLA+ +PV+++L ++ +DG L++ P
Sbjct: 254 MTSVQKQSIPVLLEGRDALVRSQTGSGKTLAYCIPVVQSLQAMESKIQRSDGPYALVLVP 313
Query: 150 TRELAYQTFEVLRKVGKNHDFSA-GLIIGGKDLKHEAERINN-INILVCTPGRLLQHMDE 207
TRELA Q+F+ ++K+ K + G+++GG+ K E R+ INIL+ TPGRL+ H+
Sbjct: 314 TRELALQSFDTVQKLLKPFTWIVPGVLMGGEKRKSEKARLRKGINILISTPGRLVDHIKS 373
Query: 208 TVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLP---KKRQTLLFSATQTKSVKDLA 264
T + H + L+ LV DEADRILD+GF + ++ + +KRQ +L SAT T+ V LA
Sbjct: 374 TKNIHFSRLRWLVFDEADRILDLGFEKDITVILNAVNAECQKRQNVLLSATLTEGVTRLA 433
Query: 265 RLSLKNPEYVWVHEKA------------------------KYSTPATLEQNYIVCELQQK 300
+SL +P + V +K+ ++ P +L+Q+ V + +
Sbjct: 434 DISLHDPVSISVLDKSHDQLNPKDKAVQEVCPPPAGDKLDSFAIPESLKQHVTVVPSKLR 493
Query: 301 ISVLYSFLRSHLK----KKSIVFFSSCKEVQYLYRVFCRL------------RPGVSI-- 342
+ L +F+ K +K +VFFSSC+ V++ Y +F + P S+
Sbjct: 494 LVCLAAFILQKCKFEEDQKMVVFFSSCELVEFHYSLFLQTLLSSSGAPASGQLPSASMRL 553
Query: 343 --LALHGRQQQMRRMEVYNEFVRKRAAVLFAT 372
L LHG +Q R V+ EF R VL T
Sbjct: 554 KFLRLHGGMEQEERTAVFQEFSHSRRGVLLCT 585
>gi|169881239 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 164 bits (416), Expect = 3e-40
Identities = 125/397 (31%), Positives = 185/397 (46%), Gaps = 35/397 (8%)
Query: 68 ITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV 127
I FSD + + + ++ +Y T +QK I + +D++ A+TGSGKT AFL+P+
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPI 236
Query: 128 LEALYRLQWTSTDGLGV--------------------LIISPTRELAYQTFEVLRKVGKN 167
L +Y TDG G L+++PTRELA Q +E RK
Sbjct: 237 LSQIY------TDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYR 290
Query: 168 HDFSAGLIIGGKDLKHEAERINN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADR 226
++ GG D+ + + ++LV TPGRL+ M E + LVLDEADR
Sbjct: 291 SRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMM-ERGKIGLDFCKYLVLDEADR 349
Query: 227 ILDMGFADTMNAVIEN--LPKK--RQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKY 282
+LDMGF + ++E +P K R T++FSAT K ++ LAR L EY+++
Sbjct: 350 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD--EYIFLAVGRVG 407
Query: 283 STPATLEQNYIVCELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSI 342
ST + Q + E K S L L + + F K+ F G +
Sbjct: 408 STSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFL-YHEGYAC 466
Query: 343 LALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHR 402
++HG + Q R E ++F ++ +L AT +AARGLD V V+ FD P D Y+HR
Sbjct: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526
Query: 403 AGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVKE 439
GRT R G A + + LL V K+
Sbjct: 527 IGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQ 563
>gi|13514809 DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
[Homo sapiens]
Length = 660
Score = 164 bits (416), Expect = 3e-40
Identities = 125/397 (31%), Positives = 185/397 (46%), Gaps = 35/397 (8%)
Query: 68 ITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPV 127
I FSD + + + ++ +Y T +QK I + +D++ A+TGSGKT AFL+P+
Sbjct: 177 IENFSDIDMGEIIMGNIELTRYTRPTPVQKHAIPIIKGKRDLMACAQTGSGKTAAFLLPI 236
Query: 128 LEALYRLQWTSTDGLGV--------------------LIISPTRELAYQTFEVLRKVGKN 167
L +Y TDG G L+++PTRELA Q +E RK
Sbjct: 237 LSQIY------TDGPGEALKAVKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYR 290
Query: 168 HDFSAGLIIGGKDLKHEAERINN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADR 226
++ GG D+ + + ++LV TPGRL+ M E + LVLDEADR
Sbjct: 291 SRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMM-ERGKIGLDFCKYLVLDEADR 349
Query: 227 ILDMGFADTMNAVIEN--LPKK--RQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKY 282
+LDMGF + ++E +P K R T++FSAT K ++ LAR L EY+++
Sbjct: 350 MLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLD--EYIFLAVGRVG 407
Query: 283 STPATLEQNYIVCELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYRVFCRLRPGVSI 342
ST + Q + E K S L L + + F K+ F G +
Sbjct: 408 STSENITQKVVWVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFL-YHEGYAC 466
Query: 343 LALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHR 402
++HG + Q R E ++F ++ +L AT +AARGLD V V+ FD P D Y+HR
Sbjct: 467 TSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHR 526
Query: 403 AGRTARYKEDGEALLILLPSEKAMVQQLLQKKVPVKE 439
GRT R G A + + LL V K+
Sbjct: 527 IGRTGRVGNLGLATSFFNEKNMNITKDLLDLLVEAKQ 563
>gi|188035877 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 [Homo
sapiens]
Length = 619
Score = 161 bits (408), Expect = 2e-39
Identities = 129/471 (27%), Positives = 231/471 (49%), Gaps = 30/471 (6%)
Query: 3 KTANSPGSGARPDPVRSFNRWKKKHSHRQNKKKQLRKQLKKPEW-QVERESISRLMQNYE 61
K +N + + P+ + + K+H N ++ + LK+ V+ + ++R + ++E
Sbjct: 147 KLSNPQKADSEPESPLNASYVYKEHPFILNLQEDQIENLKQQLGILVQGQEVTRPIIDFE 206
Query: 62 KINVNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTL 121
++ E+ + L+++ Y + T IQ Q I + L G+D+L +A TGSGKT
Sbjct: 207 HCSLPEVLNHN-----------LKKSGYEVPTPIQMQMIPVGLLGRDILASADTGSGKTA 255
Query: 122 AFLVPVL-EALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHD-FSAGLIIGGK 179
AFL+PV+ AL+ + S LI++PTRELA Q +++ L++GG
Sbjct: 256 AFLLPVIMRALFESKTPSA-----LILTPTRELAIQIERQAKELMSGLPRMKTVLLVGGL 310
Query: 180 DLKHEAERIN-NINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNA 238
L + R+ ++ +++ TPGRLL + ++ S ++++V+DEAD +L MGF +
Sbjct: 311 PLPPQLYRLQQHVKVIIATPGRLLDIIKQS-SVELCGVKIVVVDEADTMLKMGFQQQVLD 369
Query: 239 VIENLPKKRQTLLFSATQTKSVKDLARLSLKNPEYVWVHEKAKYSTP-ATLEQNYIVCEL 297
++EN+P QT+L SAT S++ LA L NP + EK + P A + Q + E
Sbjct: 370 ILENIPNDCQTILVSATIPTSIEQLASQLLHNPVRIITGEK---NLPCANVRQIILWVED 426
Query: 298 QQKISVLYSFLRSH-LKKKSIVFFSSCKEVQYLYRVFCRLRPGVSILALHGRQQQMRRME 356
K L+ L L K ++ F CK L + G+ +++H + Q+ R
Sbjct: 427 PAKKKKLFEILNDKKLFKPPVLVFVDCKLGADLLSEAVQKITGLKSISIHSEKSQIERKN 486
Query: 357 VYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFDCPEDANTYIHRAGRTARYKEDGEAL 416
+ + V+ +T + RGLD +V V+ FD P + Y+H+ GR R ++G A+
Sbjct: 487 ILKGLLEGDYEVVVSTGVLGRGLDLISVRLVVNFDMPSSMDEYVHQIGRVGRLGQNGTAI 546
Query: 417 LILLPSEKAMVQQLLQKKVPVKEI----KINPEKLIDVQKKLESILAQDQD 463
+ + K + + ++ P I +N L D ++K + Q Q+
Sbjct: 547 TFINNNSKRLFWDIAKRVKPTGSILPPQLLNSPYLHDQKRKEQQKDKQTQN 597
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.131 0.363
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,235,859
Number of Sequences: 37866
Number of extensions: 1620161
Number of successful extensions: 26341
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 460
Number of HSP's successfully gapped in prelim test: 882
Number of HSP's that attempted gapping in prelim test: 11458
Number of HSP's gapped (non-prelim): 7963
length of query: 875
length of database: 18,247,518
effective HSP length: 111
effective length of query: 764
effective length of database: 14,044,392
effective search space: 10729915488
effective search space used: 10729915488
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.