Guide to the Human Genome
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Search of human proteins with 6005958

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|6005958 V-set and immunoglobulin domain containing 4 isoform
1 [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|6005958 V-set and immunoglobulin domain containing 4 isoform ...   812   0.0  
gi|154426280 V-set and immunoglobulin domain containing 4 isofor...   343   2e-94
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]     62   9e-10
gi|8393638 F11 receptor precursor [Homo sapiens]                       60   5e-09
gi|110349719 titin isoform N2-A [Homo sapiens]                         55   1e-07
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho...    53   6e-07
gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]        52   9e-07
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]         50   5e-06
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]          50   5e-06
gi|157057547 Fc receptor-like 6 [Homo sapiens]                         50   5e-06
gi|139948432 adlican [Homo sapiens]                                    50   5e-06
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]             49   6e-06
gi|109150416 peroxidasin [Homo sapiens]                                49   1e-05
gi|189571583 intercellular adhesion molecule 5 precursor [Homo s...    49   1e-05
gi|221316757 neurotrimin isoform 3 [Homo sapiens]                      47   2e-05
gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo sap...    47   2e-05
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]                    47   4e-05
gi|118572606 hemicentin 1 [Homo sapiens]                               47   4e-05
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]         46   5e-05
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                    46   5e-05
gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo ...    46   5e-05
gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]    46   5e-05
gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]       46   5e-05
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                    45   9e-05
gi|24111244 MAM domain containing glycosylphosphatidylinositol a...    45   9e-05
gi|221316762 neurotrimin isoform 4 [Homo sapiens]                      45   1e-04
gi|115298665 neurotrimin isoform 2 [Homo sapiens]                      45   1e-04
gi|7705413 neurotrimin isoform 1 [Homo sapiens]                        45   1e-04
gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]    45   1e-04
gi|126517478 peroxidasin homolog-like [Homo sapiens]                   44   3e-04

>gi|6005958 V-set and immunoglobulin domain containing 4 isoform 1
           [Homo sapiens]
          Length = 399

 Score =  812 bits (2098), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQR 60
           MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQR
Sbjct: 1   MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQR 60

Query: 61  GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP 120
           GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP
Sbjct: 61  GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP 120

Query: 121 DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ 180
           DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ
Sbjct: 121 DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ 180

Query: 181 QTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTK 240
           QTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTK
Sbjct: 181 QTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTK 240

Query: 241 TEAPTTMTYPLKATSTVKQSWDWTTDMDGYLGETSAGPGKSLPVFAIILIISLCCMVVFT 300
           TEAPTTMTYPLKATSTVKQSWDWTTDMDGYLGETSAGPGKSLPVFAIILIISLCCMVVFT
Sbjct: 241 TEAPTTMTYPLKATSTVKQSWDWTTDMDGYLGETSAGPGKSLPVFAIILIISLCCMVVFT 300

Query: 301 MAYIMLCRKTSQQEHVYEAARAHAREANDSGETMRVAIFASGCSSDEPTSQNLGNNYSDE 360
           MAYIMLCRKTSQQEHVYEAARAHAREANDSGETMRVAIFASGCSSDEPTSQNLGNNYSDE
Sbjct: 301 MAYIMLCRKTSQQEHVYEAARAHAREANDSGETMRVAIFASGCSSDEPTSQNLGNNYSDE 360

Query: 361 PCIGQEYQIIAQINGNYARLLDTVPLDYEFLATEGKSVC 399
           PCIGQEYQIIAQINGNYARLLDTVPLDYEFLATEGKSVC
Sbjct: 361 PCIGQEYQIIAQINGNYARLLDTVPLDYEFLATEGKSVC 399


>gi|154426280 V-set and immunoglobulin domain containing 4 isoform 2
           [Homo sapiens]
          Length = 305

 Score =  343 bits (880), Expect = 2e-94
 Identities = 169/171 (98%), Positives = 169/171 (98%)

Query: 229 VVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTDMDGYLGETSAGPGKSLPVFAII 288
           V K SSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTDMDGYLGETSAGPGKSLPVFAII
Sbjct: 135 VQKHSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTDMDGYLGETSAGPGKSLPVFAII 194

Query: 289 LIISLCCMVVFTMAYIMLCRKTSQQEHVYEAARAHAREANDSGETMRVAIFASGCSSDEP 348
           LIISLCCMVVFTMAYIMLCRKTSQQEHVYEAARAHAREANDSGETMRVAIFASGCSSDEP
Sbjct: 195 LIISLCCMVVFTMAYIMLCRKTSQQEHVYEAARAHAREANDSGETMRVAIFASGCSSDEP 254

Query: 349 TSQNLGNNYSDEPCIGQEYQIIAQINGNYARLLDTVPLDYEFLATEGKSVC 399
           TSQNLGNNYSDEPCIGQEYQIIAQINGNYARLLDTVPLDYEFLATEGKSVC
Sbjct: 255 TSQNLGNNYSDEPCIGQEYQIIAQINGNYARLLDTVPLDYEFLATEGKSVC 305



 Score =  286 bits (732), Expect = 2e-77
 Identities = 138/139 (99%), Positives = 138/139 (99%)

Query: 1   MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQR 60
           MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQR
Sbjct: 1   MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQR 60

Query: 61  GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP 120
           GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP
Sbjct: 61  GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP 120

Query: 121 DGNQVVRDKITELRVQKLS 139
           DGNQVVRDKITELRVQK S
Sbjct: 121 DGNQVVRDKITELRVQKHS 139


>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
          Length = 319

 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 63/225 (28%), Positives = 102/225 (45%), Gaps = 20/225 (8%)

Query: 4   LLGLLLLGHLTVDTYGRPILEVPESVTGPWKG-DVNLPCTYDPLQGYTQVLVKW--LVQR 60
           +L  L    +TVD      +E P+ V    +G  V LPCTY       + L++W  L+  
Sbjct: 8   VLWTLCAVRVTVDAIS---VETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQWDKLLLT 64

Query: 61  GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKV-PGDVSLQLSTLEMDDRSHYTCEVTWQT 119
            ++ V I+   S+ ++I    Y+ R+ +S+     D S+ +  L M D   Y C V+  +
Sbjct: 65  HTERVVIW-PFSNKNYIHGELYKNRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMS 123

Query: 120 P-DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQAR-GSPPISYIW 177
             +GN       T+ RV+ L +  P+       G T+  G  I L CQ++ GSP   Y W
Sbjct: 124 DLEGN-------TKSRVRLLVLVPPSKPECGIEGETI-IGNNIQLTCQSKEGSPTPQYSW 175

Query: 178 YKQQTNNQEP--IKVATLSTLLFKPAVIADSGSYFCTAKGQVGSE 220
            +    NQE    + A+   +  K      SG Y CT+  + G++
Sbjct: 176 KRYNILNQEQPLAQPASGQPVSLKNISTDTSGYYICTSSNEEGTQ 220


>gi|8393638 F11 receptor precursor [Homo sapiens]
          Length = 299

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 65/240 (27%), Positives = 100/240 (41%), Gaps = 41/240 (17%)

Query: 1   MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQR 60
           + ILL  L LG +TV +   P + +PE+        V L C Y    G++   V+W   +
Sbjct: 17  LAILLCSLALGSVTVHS-SEPEVRIPEN------NPVKLSCAYS---GFSSPRVEWKFDQ 66

Query: 61  GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP 120
           G     +   +        A Y+ R+     +P  ++ +  T E  D   YTC V+ +  
Sbjct: 67  GDTTRLVCYNNKI-----TASYEDRVTF---LPTGITFKSVTRE--DTGTYTCMVSEEGG 116

Query: 121 DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQAR-GSPPISYIWYK 179
           +    V+ K+  L    +  SKPTV   S    +   G R  L C  + GSPP  Y W+K
Sbjct: 117 NSYGEVKVKLIVL----VPPSKPTVNIPS----SATIGNRAVLTCSEQDGSPPSEYTWFK 168

Query: 180 Q----QTN--------NQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVK 227
                 TN        N   +   T   L+F P   +D+G Y C A+   G+   S+ V+
Sbjct: 169 DGIVMPTNPKSTRAFSNSSYVLNPTTGELVFDPLSASDTGEYSCEARNGYGTPMTSNAVR 228


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 65/237 (27%), Positives = 100/237 (42%), Gaps = 48/237 (20%)

Query: 16   DTYGRPILEVPES-VTGPWKGDVNLP----CTYDPLQGYTQVLVKWLVQRGSDPVTIFLR 70
            D+ G  I++ P S VT P   DV LP    C     QG T + ++W   +G+  +     
Sbjct: 4195 DSSGALIVQEPPSFVTKPGSKDV-LPGSAVCLKSTFQGSTPLTIRWF--KGNKELV---- 4247

Query: 71   DSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP----DGNQVV 126
              SG         G  +++ K   + SL+L  ++  D   YTC+V+          N  V
Sbjct: 4248 --SG---------GSCYIT-KEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFV 4295

Query: 127  RDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQE 186
            ++  T   V+KL  S+            + +G    L C+  G+PPI   W+      +E
Sbjct: 4296 KEPATF--VEKLEPSQ-----------LLKKGDATQLACKVTGTPPIKITWFANDREIKE 4342

Query: 187  PIK-----VATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLK 238
              K     V + + L      I DSG Y C A+ + GS+  S IV  +VK+S    K
Sbjct: 4343 SSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIV--IVKESPYFTK 4397



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 41/167 (24%), Positives = 67/167 (40%), Gaps = 22/167 (13%)

Query: 107  DRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQ 166
            D   Y+CE+       N+  RD    L    +S  +P              G  +SLQCQ
Sbjct: 6052 DAGQYSCEIE------NEAGRDVCGAL----VSTLEPPYFVTELEPLEAAVGDSVSLQCQ 6101

Query: 167  ARGSPPISYIWYKQQTNNQEPIKVAT-----LSTLLFKPAVIADSGSYFCTAKGQVGSEQ 221
              G+P I+  WYK  T  +   +  T     ++TL+F    I DSG Y C A+  +G+  
Sbjct: 6102 VAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTAS 6161

Query: 222  HSDIVKFVVKD-------SSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
               + +   +          K ++     P T+T  L  ++ ++  W
Sbjct: 6162 SKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCW 6208



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 13/115 (11%)

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVAT-----LSTLLFKPAVIADSGSYFCT 212
            G  ++LQ   RGS PIS  W K Q   +E  K+       ++ L+     I+  G Y C 
Sbjct: 3938 GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCL 3997

Query: 213  AKGQVGSEQHSDIVKFVVKDSSK------LLKTKTEAPTTMTYPLKATSTVKQSW 261
            A+ + GS+  + + + +VK+ +K      L++     P T+ Y +  T  +K  W
Sbjct: 3998 AENEAGSQ--TSVGELIVKEPAKIIERAELIQVTAGDPATLEYTVAGTPELKPKW 4050



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 33/128 (25%), Positives = 58/128 (45%), Gaps = 15/128 (11%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            +Q++ L  +D   + CE   Q P G+     K+        S   P V T         +
Sbjct: 5481 IQMNNLSTEDSGDFICEA--QNPAGSTSCSTKVIVKEPPVFSSFPPIVET--------LK 5530

Query: 158  GMRISLQCQARGSPPISYIWY--KQQTNNQEPIKVATL---STLLFKPAVIADSGSYFCT 212
               +SL+C+  G+PP   +WY  K+Q  + +  K+A+    +++       +D G Y C 
Sbjct: 5531 NAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCK 5590

Query: 213  AKGQVGSE 220
            A+ +VGS+
Sbjct: 5591 AQNEVGSD 5598



 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 7/113 (6%)

Query: 138  LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATL-- 193
            L+V  P V T         +G  + LQC+  G+PP   +W K  +Q  N +  K+ +   
Sbjct: 6452 LTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHF 6511

Query: 194  -STLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPT 245
             ++L       +D G Y C A  +VGS+  S  VKF  K+  + +K  ++  T
Sbjct: 6512 DTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKF--KEPPRFVKKLSDTST 6562



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 35/166 (21%), Positives = 66/166 (39%), Gaps = 17/166 (10%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L++  L ++D   YTCE        +              L V +P +     +     +
Sbjct: 7363 LEMHNLSVEDSGDYTCEAHNAAGSASSST----------SLKVKEPPIFRKKPHPIETLK 7412

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI-----ADSGSYFCT 212
            G  + L+C+ +G+PP    WYK +   +   K   +S        I     AD G Y C 
Sbjct: 7413 GADVHLECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCK 7472

Query: 213  AKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVK 258
            A   VGS+  + +    +K   + +K  ++  T +   ++  +T++
Sbjct: 7473 ATNDVGSD--TCVGSIALKAPPRFVKKLSDISTVVGKEVQLQTTIE 7516



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 36/127 (28%), Positives = 53/127 (41%), Gaps = 16/127 (12%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP- 156
            L++  +   D   YTC+ T      N V +D  +     +LSV +P           V  
Sbjct: 6328 LRILKVGKGDSGQYTCQAT------NDVGKDMCSA----QLSVKEPPKFVKKLEASKVAK 6377

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEPIK-----VATLSTLLFKPAVIADSGSYFC 211
            QG  I L+C+  GSP I   W++  +   E  K     + +++ L    A   DSG Y C
Sbjct: 6378 QGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYIC 6437

Query: 212  TAKGQVG 218
             A   VG
Sbjct: 6438 EAHNGVG 6444



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 26/69 (37%), Positives = 32/69 (46%), Gaps = 5/69 (7%)

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVA-----TLSTLLFKPAVIADSGSY 209
            V  G   SLQCQ  G+P I   WYK  T  +            ++TL+F    I DSG Y
Sbjct: 7972 VSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEY 8031

Query: 210  FCTAKGQVG 218
             C A+  VG
Sbjct: 8032 ICKAENSVG 8040



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 52/183 (28%), Positives = 80/183 (43%), Gaps = 34/183 (18%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQV-VRDKITELRVQKLSVSKPTVTTGSG 150
            V G  SL++  ++M+D  ++TC  T      N V  +D    L VQ+     P+  T  G
Sbjct: 4164 VEGTASLEIIRVDMNDAGNFTCRAT------NSVGSKDSSGALIVQE----PPSFVTKPG 4213

Query: 151  YGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPI--------KVATLSTLLFKPAV 202
                +P G  + L+   +GS P++  W+K    N+E +        K A  S+L      
Sbjct: 4214 SKDVLP-GSAVCLKSTFQGSTPLTIRWFK---GNKELVSGGSCYITKEALESSLELYLVK 4269

Query: 203  IADSGSYFCTAKGQVGSEQHS------DIVKFVVK-DSSKLLK----TKTEAPTTMTYPL 251
             +DSG+Y C      G  + S      +   FV K + S+LLK    T+     T T P+
Sbjct: 4270 TSDSGTYTCKVSNVAGGVECSANLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGTPPI 4329

Query: 252  KAT 254
            K T
Sbjct: 4330 KIT 4332



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 9/107 (8%)

Query: 164  QCQARGSPPISYIWYKQQTNNQEPIK-----VATLSTLLFKPAVIADSGSYFCTAKGQVG 218
            +C+  GSP I  +WYK +T  QE  K     V +++ L      + DSG Y C A    G
Sbjct: 7326 ECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAG 7385

Query: 219  SEQHSDIVKF----VVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
            S   S  +K     + +     ++T   A   +   L+ T     SW
Sbjct: 7386 SASSSTSLKVKEPPIFRKKPHPIETLKGADVHLECELQGTPPFHVSW 7432



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 37/150 (24%), Positives = 64/150 (42%), Gaps = 14/150 (9%)

Query: 137  KLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKV-----A 191
            ++ V+ PT+ +G     TV +G  ++L+C   G P  +  WY++    +  I       +
Sbjct: 937  EIPVTPPTLVSGLK-NVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQS 995

Query: 192  TLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDS-SKLLKTKTEAPTTMTYP 250
             ++ L+ + A   DSG + C+A  + G+   S  +   V +   K     TE  TT    
Sbjct: 996  GIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKR 1055

Query: 251  LKATSTVKQSWDWTTDMDGYLGETSAGPGK 280
               +  V  +       D  L E  AGPG+
Sbjct: 1056 FVESRDVVMT-------DTSLTEEQAGPGE 1078



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 27/87 (31%), Positives = 40/87 (45%), Gaps = 7/87 (8%)

Query: 158  GMRISLQCQARGSPPISYIWYKQ-----QTNNQEPIKVATLSTLLFKPAVIADSGSYFCT 212
            G    L C+ +GSP I   W+K      ++N      V + + L      + DSGSY C 
Sbjct: 3752 GESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCE 3811

Query: 213  AKGQVGSEQHSDIVKFVVKDSSKLLKT 239
            A   VGS+  S   + V+K+    +KT
Sbjct: 3812 AVNDVGSDSCS--TEIVIKEPPSFIKT 3836



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 61/256 (23%), Positives = 92/256 (35%), Gaps = 51/256 (19%)

Query: 11   GHLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTI-FL 69
            GHLTV        E P  V  P   DVN           T+V +K LV  G+ P+TI + 
Sbjct: 4760 GHLTVK-------EPPYFVEKPQSQDVN---------PNTRVQLKALVG-GTAPMTIKWF 4802

Query: 70   RDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDK 129
            +D+   H       G      K     SL+L   +  D   Y C+++    D        
Sbjct: 4803 KDNKELH------SGAARSVWKDDTSTSLELFAAKATDSGTYICQLS---NDVGTATSKA 4853

Query: 130  ITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIK 189
               ++     + KP+          +  G   + +CQ  G+P I   WY          K
Sbjct: 4854 TLFVKEPPQFIKKPSPV------LVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQK 4907

Query: 190  -----VATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAP 244
                 +  L+T     A + +SG+Y C A+   G+             +S  ++ K + P
Sbjct: 4908 HGISFIDGLATFQISGARVENSGTYVCEARNDAGT-------------ASCSIELKVKEP 4954

Query: 245  TTMTYPLKATSTVKQS 260
             T    LK    VK S
Sbjct: 4955 PTFIRELKPVEVVKYS 4970



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 64/254 (25%), Positives = 94/254 (37%), Gaps = 47/254 (18%)

Query: 22   ILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQAK 81
            I+E PES+         L CT   + G  ++  KW             ++ + D+    K
Sbjct: 7588 IVEKPESIKVTTGDTCTLECT---VAGTPELSTKWFKDG---------KELTSDN----K 7631

Query: 82   YQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVS 141
            Y  ++   +KV G   L++  +   D   Y+ EV       N V +D  T      L VS
Sbjct: 7632 Y--KISFFNKVSG---LKIINVAPSDSGVYSFEVQ------NPVGKDSCTA----SLQVS 7676

Query: 142  KPTVTTGSGYGFTVPQGMR---ISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST--- 195
              TV            G+    + ++C+  GSPPIS  W+ +        K  T  T   
Sbjct: 7677 DRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNT 7736

Query: 196  --LLFKPAVIADSGSYFCTAKGQVGSEQHS------DIVKFVVKDSSKLLKTKTEAPTTM 247
              L       +DSG Y C A    GS++ S      +   FV K     + T T    T 
Sbjct: 7737 CALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTN--VTF 7794

Query: 248  TYPLKATSTVKQSW 261
            T  +K T     SW
Sbjct: 7795 TSIVKGTPPFSVSW 7808



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 46/182 (25%), Positives = 72/182 (39%), Gaps = 22/182 (12%)

Query: 61   GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMD--DRSHYTCEVTWQ 118
            G+ P+ +     S +     KYQ    +S+    + S  L+ L++D  D   YTC     
Sbjct: 8178 GTQPIKVSWAKDSREIRSGGKYQ----ISYL---ENSAHLTVLKVDKGDSGQYTCYAV-- 8228

Query: 119  TPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWY 178
                N+V +D  T     K  +  P+ T          +G    L+ +  GS PI+  WY
Sbjct: 8229 ----NEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWY 8284

Query: 179  K-----QQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDS 233
            K     Q T+N E         L  + A + D+G Y C      GS   +  +  V+K+ 
Sbjct: 8285 KNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSI--VIKEP 8342

Query: 234  SK 235
             K
Sbjct: 8343 KK 8344



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 44/179 (24%), Positives = 69/179 (38%), Gaps = 30/179 (16%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELR--VQKLSVSKPTVTTGSGYGFTV 155
            L L +++      YTC VT      +      +TE    V+KL  SK            V
Sbjct: 5387 LNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPKFVKKLEASK-----------IV 5435

Query: 156  PQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI-------ADSGS 208
              G    L+C+  GSP I  +W++ +  ++ P       T +   AVI        DSG 
Sbjct: 5436 KAGDSSRLECKIAGSPEIRVVWFRNE--HELPASDKYRMTFIDSVAVIQMNNLSTEDSGD 5493

Query: 209  YFCTAKGQVGSEQHSDIVKFVVKDS------SKLLKTKTEAPTTMTYPLKATSTVKQSW 261
            + C A+   GS   S   K +VK+         +++T   A  ++   L  T   +  W
Sbjct: 5494 FICEAQNPAGSTSCS--TKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVW 5550



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 48/199 (24%), Positives = 75/199 (37%), Gaps = 34/199 (17%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            SL++   EM D+  Y+ EV       N  V   +++  V    + K              
Sbjct: 6701 SLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAI------- 6753

Query: 157  QGMRISLQCQARGSPPISYIWY----------KQQTNNQEPIKVATLSTLLFKPAVIADS 206
             G  + L+C+  GS PIS  W+          K Q++  E   V TL+  L +P   +D+
Sbjct: 6754 LGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSE--NVCTLNLSLLEP---SDT 6808

Query: 207  GSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEA----PTTMTYPLKATSTVKQSWD 262
            G Y C A    GS++ S ++      S +      E       T T  ++ T   K  W 
Sbjct: 6809 GIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKW- 6867

Query: 263  WTTDMDGYLGETSAGPGKS 281
                   + G     PG+S
Sbjct: 6868 -------FKGSRELVPGES 6879



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 14/140 (10%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQ+    M+D   YTC+V+     G+ +    I     +K  V    +T       TV +
Sbjct: 8307 LQVRKAGMNDAGLYTCKVS--NDAGSALCTSSIVIKEPKKPPVFDQHLTP-----VTVSE 8359

Query: 158  GMRISLQCQARGSPPISYIWYKQ----QTNNQEPIKVATLSTLL-FKPAVIADSGSYFCT 212
            G  + L C  +GS PI   W K     + +++     A+ + +L  +    ADSG Y C 
Sbjct: 8360 GEYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCK 8419

Query: 213  AKGQVGSEQHSDIVKFVVKD 232
            A    GS+      K  +KD
Sbjct: 8420 ASNVAGSDTTKS--KVTIKD 8437



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 30/132 (22%), Positives = 55/132 (41%), Gaps = 12/132 (9%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +L  + + ++D   YTC+      + +       T  R+Q+  +             TV 
Sbjct: 6135 TLVFNKVNINDSGEYTCKA-----ENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTV- 6188

Query: 157  QGMRISLQCQARGSPPISYIWYK-----QQTNNQEPIKVATLSTLLFKPAVIADSGSYFC 211
             G+ ++L C+  GS PI   WY+     +   N +   V  ++TL      ++ SG Y C
Sbjct: 6189 -GLPVTLTCRLNGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSC 6247

Query: 212  TAKGQVGSEQHS 223
            +A   +G+   S
Sbjct: 6248 SASNPLGTASSS 6259



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 38/131 (29%), Positives = 54/131 (41%), Gaps = 12/131 (9%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L++ + E  D   YT EV       N V R    + R+  L +  P   T         +
Sbjct: 4636 LKIISTEKKDSGEYTFEVQ------NDVGRSSC-KARINVLDLIIPPSFTKKLKKMDSIK 4688

Query: 158  GMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVA---TLSTLLFKPAVIADSGSYFCT 212
            G  I L+C   GS PIS  W+K  Q+ +  E  K +     + L        DSG+Y C+
Sbjct: 4689 GSFIDLECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCS 4748

Query: 213  AKGQVGSEQHS 223
            A  + G  Q S
Sbjct: 4749 ATNKAGHNQCS 4759



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 41/184 (22%), Positives = 68/184 (36%), Gaps = 26/184 (14%)

Query: 95   DVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELR--VQKLSVSKPTVTTGSGYG 152
            D SL +  LE  D   Y C+ T +          K  E    V+KLS +   +       
Sbjct: 6512 DTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLI------- 6564

Query: 153  FTVPQGMRISLQCQARGSPPISYIWYK------QQTNNQEPIKVATLSTLLFKPAVIADS 206
                 G  + L+    G  PIS +W K      +++ N     +  ++TL       ++S
Sbjct: 6565 -----GDAVELRAIVEGFQPISVVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNS 6619

Query: 207  GSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLK----ATSTVKQSWD 262
            G Y C  K   G  + S ++   V + +++++       T   P       T T + S  
Sbjct: 6620 GKYICQIKNDAGMRECSAVL--TVLEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAK 6677

Query: 263  WTTD 266
            W  D
Sbjct: 6678 WFKD 6681



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 37/155 (23%), Positives = 66/155 (42%), Gaps = 22/155 (14%)

Query: 96   VSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTV 155
            VSL+++ LE++D ++YTC+V+      N    D  + +   K     P+     G    +
Sbjct: 5292 VSLEVNNLELEDTANYTCKVS------NVAGDDACSGILTVK---EPPSFLVKPGRQQAI 5342

Query: 156  PQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKV-----ATLSTLLFKPAVIADSGSYF 210
            P    +  +   +G+PP    W+K         K       + S L       + +G Y 
Sbjct: 5343 PDS-TVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYT 5401

Query: 211  CTAKGQVGSEQHSDIV------KFVVK-DSSKLLK 238
            C     VGS+  + ++      KFV K ++SK++K
Sbjct: 5402 CHVTNDVGSDSCTTMLLVTEPPKFVKKLEASKIVK 5436



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 35/135 (25%), Positives = 55/135 (40%), Gaps = 22/135 (16%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITEL-----RVQKLSVSKPTVTTGSGY 151
            SL++ ++E  D   YT +V       N V +   T +     R    S ++    TG   
Sbjct: 5760 SLRILSVERQDAGTYTFQVQ------NNVGKSSCTAVVDVSDRAVPPSFTRRLKNTGGVL 5813

Query: 152  GFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVAT-----LSTLLFKPAVIADS 206
            G +        L+C+  GS PIS  W+ ++T      K  T     + TL       +D 
Sbjct: 5814 GASC------ILECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQLNSLDSSDM 5867

Query: 207  GSYFCTAKGQVGSEQ 221
            G+Y C A    GS++
Sbjct: 5868 GNYTCVAANVAGSDE 5882



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 51/218 (23%), Positives = 80/218 (36%), Gaps = 32/218 (14%)

Query: 61   GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP 120
            GS P+++         +  AKYQ     S  V    +LQL++L+  D  +YTC       
Sbjct: 5825 GSSPISVAWFHEKTKIVSGAKYQTTF--SDNV---CTLQLNSLDSSDMGNYTCVAA---- 5875

Query: 121  DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ 180
              N    D+   +    L+V +P           V  G  ++     RG+PP    W++ 
Sbjct: 5876 --NVAGSDECRAV----LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFR- 5928

Query: 181  QTNNQEPIK--------VATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKD 232
                +E +K          T++ L      I+ SG Y C      G  Q S   +  VK+
Sbjct: 5929 --GARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG--QASCTTRLFVKE 5984

Query: 233  SSKLLKT----KTEAPTTMTYPLKATSTVKQSWDWTTD 266
             +  LK       E   ++      T T+  S  W  D
Sbjct: 5985 PAAFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKD 6022



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 41/181 (22%), Positives = 72/181 (39%), Gaps = 38/181 (20%)

Query: 46   LQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEM 105
            ++G+  + V WL  RG       +R+S    I              +    +LQL + E 
Sbjct: 6574 VEGFQPISVVWLKDRGE-----VIRESENTRISF------------IDNIATLQLGSPEA 6616

Query: 106  DDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKP---TVTTGSGYGFTVPQGMRIS 162
             +   Y C++  +   G +     +T L   ++ + KP   TVTTG+ +          +
Sbjct: 6617 SNSGKYICQI--KNDAGMRECSAVLTVLEPARI-IEKPEPMTVTTGNPF----------A 6663

Query: 163  LQCQARGSPPISYIWYKQQTNNQEPIK-----VATLSTLLFKPAVIADSGSYFCTAKGQV 217
            L+C   G+P +S  W+K         K     +  +++L    A ++D G Y    K  V
Sbjct: 6664 LECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSV 6723

Query: 218  G 218
            G
Sbjct: 6724 G 6724



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 38/168 (22%), Positives = 70/168 (41%), Gaps = 25/168 (14%)

Query: 61   GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP 120
            G++P+++      G+ ++++     + +S+      +LQ S +E  +   YTC       
Sbjct: 7517 GAEPISVVWFKDKGEIVRESD---NIWISYS-ENIATLQFSRVEPANAGKYTC------- 7565

Query: 121  DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ 180
               Q+  D   +     LSV +P           V  G   +L+C   G+P +S  W+K 
Sbjct: 7566 ---QIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKD 7622

Query: 181  ----QTNNQEPI----KVATLSTLLFKPAVIADSGSYFCTAKGQVGSE 220
                 ++N+  I    KV+ L  +   P   +DSG Y    +  VG +
Sbjct: 7623 GKELTSDNKYKISFFNKVSGLKIINVAP---SDSGVYSFEVQNPVGKD 7667



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 41/183 (22%), Positives = 74/183 (40%), Gaps = 25/183 (13%)

Query: 98    LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTV--TTGSGYGFTV 155
             L+ +   +++   Y   +  Q   G    R+ +T + VQ L V  PT+  +T       V
Sbjct: 29692 LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVL-PTIDLSTMPQKTIHV 29750

Query: 156   PQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVAT-----LSTLLFKPAVIADSGSYF 210
             P G  + L     G PP +  W+   +  +E  +V       ++ L  +   I D+G Y 
Sbjct: 29751 PAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYT 29810

Query: 211   CTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKA----TSTVKQSWDWTTD 266
                K   G+   S+ +K ++ D           P   T P+K      +++  SW+   +
Sbjct: 29811 LELKNVTGTT--SETIKVIILDK----------PGPPTGPIKIDEIDATSITISWE-PPE 29857

Query: 267   MDG 269
             +DG
Sbjct: 29858 LDG 29860



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 43/182 (23%), Positives = 74/182 (40%), Gaps = 36/182 (19%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTP----DGNQVVRDK---ITELRVQKLSVSKPTVTTGSG 150
            L+LS L + DR  Y+C+ + +          ++ DK   I EL   + +++K        
Sbjct: 3608 LELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINK-------- 3659

Query: 151  YGFTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVA---TLSTLLFKPAVIAD 205
                     ++ L+CQ      ++  W K  Q+    +  K+     ++TL    A + D
Sbjct: 3660 ---------KVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKD 3710

Query: 206  SGSYFCTAKGQVGSEQHSDIV------KFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQ 259
            SG+Y CTA  + GS   S  V       FV K     L    E+   +   LK +  ++ 
Sbjct: 3711 SGTYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGES-ARLHCKLKGSPVIQV 3769

Query: 260  SW 261
            +W
Sbjct: 3770 TW 3771



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 33/175 (18%), Positives = 66/175 (37%), Gaps = 20/175 (11%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            S+ +  ++  D   Y C+ T           D  ++  V  +++  P          +  
Sbjct: 7455 SIHILNVDAADIGEYQCKAT----------NDVGSDTCVGSIALKAPPRFVKKLSDISTV 7504

Query: 157  QGMRISLQCQARGSPPISYIWYK------QQTNNQEPIKVATLSTLLFKPAVIADSGSYF 210
             G  + LQ    G+ PIS +W+K      ++++N        ++TL F     A++G Y 
Sbjct: 7505 VGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYT 7564

Query: 211  CTAKGQVGSEQ----HSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
            C  K   G ++     S +    + +  + +K  T    T+   +  T  +   W
Sbjct: 7565 CQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKW 7619



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 32/127 (25%), Positives = 50/127 (39%), Gaps = 15/127 (11%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L+L+ + ++D   Y CE        N+   D  + + + K S       T       V +
Sbjct: 4357 LRLTDVGIEDSGEYMCEAQ------NEAGSDHCSSIVIVKES----PYFTKEFKPIEVLK 4406

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVAT-----LSTLLFKPAVIADSGSYFCT 212
               + L  +  G+PP    W+K  T  +   K  T     L +L     V AD+G Y C 
Sbjct: 4407 EYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCR 4466

Query: 213  AKGQVGS 219
               +VGS
Sbjct: 4467 VTNEVGS 4473



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 42/178 (23%), Positives = 73/178 (41%), Gaps = 29/178 (16%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY 151
            + G  + Q+S   +++   Y CE             D  T     +L V +P        
Sbjct: 4913 IDGLATFQISGARVENSGTYVCEAR----------NDAGTASCSIELKVKEPPTFIRELK 4962

Query: 152  GFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI-------- 203
               V +   + L+C+  G+PP    W K   NN+E I+ +   TL  + +V         
Sbjct: 4963 PVEVVKYSDVELECEVTGTPPFEVTWLK---NNRE-IRSSKKYTLTDRVSVFNLHITKCD 5018

Query: 204  -ADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQS 260
             +D+G Y C    + GS   S   +  +K+    +K K E  TT+   LK+++T + +
Sbjct: 5019 PSDTGEYQCIVSNEGGSCSCS--TRVALKEPPSFIK-KIENTTTV---LKSSATFQST 5070



 Score = 35.8 bits (81), Expect = 0.070
 Identities = 45/165 (27%), Positives = 69/165 (41%), Gaps = 22/165 (13%)

Query: 60   RGSDPVTI-FLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQ 118
            +GS P+T+ +L+DS  D I +     R+   + V    SL LS +E+     Y C+    
Sbjct: 4510 KGSLPITVTWLKDS--DEITEDD-NIRMTFENNV---ASLYLSGIEVKHDGKYVCQAK-- 4561

Query: 119  TPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWY 178
                N     + + L    LSV +P   T       V QG   +LQ +  G+  I+  W+
Sbjct: 4562 ----NDAGIQRCSAL----LSVKEPATITEEAVSIDVTQGDPATLQVKFSGTKEITAKWF 4613

Query: 179  K--QQTNNQEPIKVA---TLSTLLFKPAVIADSGSYFCTAKGQVG 218
            K  Q+       K++   T+S L        DSG Y    +  VG
Sbjct: 4614 KDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQNDVG 4658



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 9/109 (8%)

Query: 162  SLQCQARGSPPISYIWYK-----QQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQ 216
            + Q    GSPPIS  W K      + +N     V +++TL  +      SG Y C AK +
Sbjct: 5066 TFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNE 5125

Query: 217  VGSEQHSDIV----KFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
             G E+    +       + + +K +    + P T+   +  T  +K  W
Sbjct: 5126 SGVERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKW 5174



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 31/135 (22%), Positives = 53/135 (39%), Gaps = 15/135 (11%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +LQ +  E  +   Y C          Q+  D      +  L V +P V        TV 
Sbjct: 5667 TLQFAKAEPANAGKYIC----------QIKNDGGMRENMATLMVLEPAVIVEKAGPMTVT 5716

Query: 157  QGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVA---TLSTLLFKPAVIADSGSYFC 211
             G   +L+C+  G+P +S  WYK  +   + +  K +    +S+L        D+G+Y  
Sbjct: 5717 VGETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTF 5776

Query: 212  TAKGQVGSEQHSDIV 226
              +  VG    + +V
Sbjct: 5777 QVQNNVGKSSCTAVV 5791



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 5/74 (6%)

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVA-----TLSTLLFKPAVIADSGSYFCT 212
            G   +LQC+  G+P I   WYK+ T  +            +++L+      +D G Y C 
Sbjct: 7034 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCK 7093

Query: 213  AKGQVGSEQHSDIV 226
            A   VG+   S ++
Sbjct: 7094 ADNSVGAVASSAVL 7107



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 30/133 (22%), Positives = 53/133 (39%), Gaps = 9/133 (6%)

Query: 138  LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQ----TNNQEPIKVATL 193
            L V +P         F+V  G  I L+    G+PPIS  W K +     + +  I +   
Sbjct: 6921 LFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEK 6980

Query: 194  STLL-FKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVK----DSSKLLKTKTEAPTTMT 248
            ST+L    + I D   Y C  + + G +    +V  +      +  + ++     P T+ 
Sbjct: 6981 STILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQ 7040

Query: 249  YPLKATSTVKQSW 261
              +  T  ++ SW
Sbjct: 7041 CKVDGTPEIRISW 7053



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 27/132 (20%), Positives = 55/132 (41%), Gaps = 15/132 (11%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY 151
            V  +  L ++ ++++D   Y+CE        N V  D  +     ++ + +P     +  
Sbjct: 3789 VNSEAILDITDVKVEDSGSYSCEAV------NDVGSDSCST----EIVIKEPPSFIKTLE 3838

Query: 152  GFTVPQGMRISLQCQARGSPPISYIWY--KQQTNNQEPIKVATLSTLLFKPAV---IADS 206
               + +G    LQC+  G+ P    W+  K+Q  + +  ++ +  +L+         AD 
Sbjct: 3839 PADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADV 3898

Query: 207  GSYFCTAKGQVG 218
            G Y C    +VG
Sbjct: 3899 GEYECVVANEVG 3910



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 5/71 (7%)

Query: 158  GMRISLQCQARGSPPISYIWYK-----QQTNNQEPIKVATLSTLLFKPAVIADSGSYFCT 212
            G+ +   C   GS PIS  WYK     + + N +   +   +TL       + +G Y CT
Sbjct: 8071 GLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCT 8130

Query: 213  AKGQVGSEQHS 223
            A   +GS   S
Sbjct: 8131 ATNPIGSASSS 8141



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 44/212 (20%), Positives = 72/212 (33%), Gaps = 37/212 (17%)

Query: 78    QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQ--TPDGN--------QVVR 127
             ++ K  G     +   G   L+++ L   D+  Y CE++ +  T   N        + + 
Sbjct: 32756 KKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEISGEGGTSKTNLQFMGQAFKSIH 32815

Query: 128   DKITELRVQKLS---------------------VSKPTVTTGSGYGFTVPQGMRISLQCQ 166
             +K++++   K S                      SKP + TG     TV          +
Sbjct: 32816 EKVSKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVIVTGL-QDTTVSSDSVAKFAVK 32874

Query: 167   ARGSPPISYIWYKQQTNNQEPIKVATLST-----LLFKPAVIADSGSYFCTAKGQVGSEQ 221
             A G P  + IW K      +  K           L       +DSG Y CT K   GS  
Sbjct: 32875 ATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVS 32934

Query: 222   HSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKA 253
              S  +       ++  K  T+  + +T   KA
Sbjct: 32935 SSCKLTIKAIKDTEAQKVSTQKTSEITPQKKA 32966



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 15/92 (16%)

Query: 158  GMRISLQCQARGSPPISYIWYK-----QQTNNQEPIKVATLSTLLFKPAVIADSGSYFCT 212
            G  ++ +C+  GS P+   WYK     +   N +   V  ++TL       +  G Y C+
Sbjct: 7130 GFPVAFECRINGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCS 7189

Query: 213  AKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAP 244
            A   +G+             S+KL+ ++ E P
Sbjct: 7190 ASNPLGT----------ASSSAKLILSEHEVP 7211



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 37/151 (24%), Positives = 60/151 (39%), Gaps = 27/151 (17%)

Query: 89   SHKVPGD---VSLQLSTLEMD-------DRSHYTCEVTWQTPDGNQVVRDKITELRVQKL 138
            S  VPGD   VSL+ S  E++           YTC V+      N+  +   T      L
Sbjct: 7813 SELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVS------NEAGKASCTT----HL 7862

Query: 139  SVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST--- 195
             +  P         +++ +G  + L+    G+PPIS  W K+   N  P +   ++T   
Sbjct: 7863 YIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTW-KKNGINVTPSQRCNITTTEK 7921

Query: 196  ---LLFKPAVIADSGSYFCTAKGQVGSEQHS 223
               L    + + D+G Y C  +   G +  S
Sbjct: 7922 SAILEIPSSTVEDAGQYNCYIENASGKDSCS 7952



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 15/108 (13%)

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVAT-----LSTLLFKPAVIADSGSY 209
            V  G      C+ + +P + + W+K      E  K +      +S+L      + D G Y
Sbjct: 3467 VALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEY 3526

Query: 210  FCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTV 257
             C A  + GS          V  ++ L  T+   PT ++ P   T+ V
Sbjct: 3527 TCKASNEYGS----------VSCTATLTVTEAYPPTFLSRPKSLTTFV 3564



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 41/186 (22%), Positives = 64/186 (34%), Gaps = 28/186 (15%)

Query: 61   GSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP 120
            GS P+++       +     KYQ  L          +L ++ LE  D   YTC  T    
Sbjct: 7707 GSPPISVSWFHEGNEISSGRKYQTTL-----TDNTCALTVNMLEESDSGDYTCIAT---- 7757

Query: 121  DGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK- 179
              N    D+ +      L+V +P           V  G  ++     +G+PP S  W+K 
Sbjct: 7758 --NMAGSDECSA----PLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKG 7811

Query: 180  -------QQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKD 232
                    + N      VA L          + SG Y C    + G  + S      +K 
Sbjct: 7812 SSELVPGDRCNVSLEDSVAELELF---DVDTSQSGEYTCIVSNEAG--KASCTTHLYIKA 7866

Query: 233  SSKLLK 238
             +K +K
Sbjct: 7867 PAKFVK 7872



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 23/100 (23%), Positives = 45/100 (45%), Gaps = 7/100 (7%)

Query: 155   VPQGMRISLQCQARGSPPISYIWYKQQ-----TNNQEPIKVATLSTLLFKPAVIADSGSY 209
             + +G  +   C+  G P     W+K       ++N    +   + +L  + A ++DSG Y
Sbjct: 33145 INEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNASVSDSGKY 33204

Query: 210   FCTAKGQVG--SEQHSDIVKFVVKDSSKLLKTKTEAPTTM 247
                AK   G  S   S +V  +V++ S+ +  +T   T++
Sbjct: 33205 TIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSL 33244



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 19/112 (16%)

Query: 105   MDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQ 164
             +DD + Y+CEV      G   V             + +  V T +     V +   I L 
Sbjct: 12437 LDDEAEYSCEVRTARTSGMLTV-------------LEEEAVFTKNLANIEVSETDTIKLV 12483

Query: 165   CQARGSPPISYIWYKQ-----QTNNQEPIKVATLSTLLFKPAVIADSGSYFC 211
             C+    P    IWYK      +T   E +       L+ + A + D+G+Y C
Sbjct: 12484 CEV-SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNC 12534



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 29/150 (19%), Positives = 59/150 (39%), Gaps = 23/150 (15%)

Query: 125   VVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNN 184
             ++++   E       ++   +T  +G  FT      I +    R +P +++   + +   
Sbjct: 28637 IIKEPQIEPTADLTGITNQLITCKAGSPFT------IDVPISGRPAPKVTWKLEEMRLKE 28690

Query: 185   QEPIKVATL---STLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKT 241
              + + + T    +TL  K ++  DSG YF T +   G +  S  V  + +          
Sbjct: 28691 TDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGR---------- 28740

Query: 242   EAPTTMTYPLKATSTVKQS--WDWTTDMDG 269
               P  +T P++ +S   +S    W    DG
Sbjct: 28741 --PGPVTGPIEVSSVSAESCVLSWGEPKDG 28768



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 29/128 (22%), Positives = 46/128 (35%), Gaps = 15/128 (11%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L+L  +++     YTC V+      +   R          L V +P          +V  
Sbjct: 5950 LELFNIDISQSGEYTCVVSNNAGQASCTTR----------LFVKEPAAFLKRLSDHSVEP 5999

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST-----LLFKPAVIADSGSYFCT 212
            G  I L+    G+ PIS  W K   N     K   ++T     L    +   D+G Y C 
Sbjct: 6000 GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCE 6059

Query: 213  AKGQVGSE 220
             + + G +
Sbjct: 6060 IENEAGRD 6067



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 6/106 (5%)

Query: 129   KITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ----QTNN 184
             +I+E  V K    KPT+   + +   V +G ++S+    R  P  +  W+K     + ++
Sbjct: 14373 EISENVVAKDPDCKPTIDLET-HDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASD 14431

Query: 185   QEPIKVATLSTLLFKP-AVIADSGSYFCTAKGQVGSEQHSDIVKFV 229
             +  +K   +S  L  P +V AD+G Y  T + ++GS   S  VK +
Sbjct: 14432 RLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVI 14477



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 19/73 (26%), Positives = 30/73 (41%), Gaps = 4/73 (5%)

Query: 152   GFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPI----KVATLSTLLFKPAVIADSG 207
             G  +  G  + +     G P  + +W K++    +       V T S L+ K A+  D G
Sbjct: 15113 GIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHG 15172

Query: 208   SYFCTAKGQVGSE 220
              Y  TA    GS+
Sbjct: 15173 RYVITATNSCGSK 15185



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 19/75 (25%), Positives = 33/75 (44%), Gaps = 5/75 (6%)

Query: 158   GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST-----LLFKPAVIADSGSYFCT 212
             G+ + L    +G PP    W K   N ++ I +   ST     L  +     D+G Y  T
Sbjct: 19708 GVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT 19767

Query: 213   AKGQVGSEQHSDIVK 227
              +   G ++++ +VK
Sbjct: 19768 LENSCGKKEYTIVVK 19782



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 34/167 (20%), Positives = 63/167 (37%), Gaps = 6/167 (3%)

Query: 91    KVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSG 150
             +V   +SLQ S  ++ +   YT  V+ +  +G +    +IT +    +      +     
Sbjct: 19931 RVMKSLSLQYSAKDLTEGKEYTFRVSAENENG-EGTPSEITVVARDDVVAPDLDLKGLPD 19989

Query: 151   YGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS-----TLLFKPAVIAD 205
               +   +     L+   +G P  S  W K +       +V+  S     TL+      +D
Sbjct: 19990 LCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSD 20049

Query: 206   SGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLK 252
             +G Y  T K   G+++ +  +K V K        K +  T     LK
Sbjct: 20050 AGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLK 20096



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 11/84 (13%)

Query: 163  LQCQARGSPPISYIWYK--QQTNNQEPIKVATL---STLLFKPAVIADSGSYFCTAKGQV 217
            L C+  GS P+   W+K  ++    +  ++A +   ++L      + D+G++ C A   V
Sbjct: 4132 LDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSV 4191

Query: 218  GSEQHSDIV------KFVVKDSSK 235
            GS+  S  +       FV K  SK
Sbjct: 4192 GSKDSSGALIVQEPPSFVTKPGSK 4215



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 32/124 (25%), Positives = 55/124 (44%), Gaps = 14/124 (11%)

Query: 13    LTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDS 72
             L V   GRP    PE   G   G++      D    +T +++  + +  S   T+ L +S
Sbjct: 22962 LFVPIKGRP---TPEVKWGKVDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENS 23018

Query: 73    SGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTP--DGNQVVRDKI 130
             SG   + A    R+  +   P  V+L+++ +  D  S     +TW+ P  DG   +++ I
Sbjct: 23019 SG--TKSAFVTVRVLDTPSPP--VNLKVTEITKDSVS-----ITWEPPLLDGGSKIKNYI 23069

Query: 131   TELR 134
              E R
Sbjct: 23070 VEKR 23073


>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
           sapiens]
          Length = 365

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 66/237 (27%), Positives = 104/237 (43%), Gaps = 31/237 (13%)

Query: 1   MGILLGLLLLGHLTVDTYGRPILEVPESVTGPWKGDVN-LPC--TYDPLQGYTQVLVKWL 57
           M +LL  +LL  + VD      +  PE +    KG+   LPC  T  P +    + ++WL
Sbjct: 1   MALLLCFVLLCGV-VDFARSLSITTPEEMIEKAKGETAYLPCKFTLSP-EDQGPLDIEWL 58

Query: 58  VQRGS----DPVTIFLRDSSGDHIQQAKY---QGRLHVSHK--VPGDVSLQLSTLEMDDR 108
           +        D V I     SGD I    Y   +GR+H +      GD S+ ++ L++ D 
Sbjct: 59  ISPADNQKVDQVIILY---SGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDI 115

Query: 109 SHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQAR 168
             Y C+V  + P    V   KI  + + K S ++  V      G          ++C+ +
Sbjct: 116 GTYQCKVK-KAPG---VANKKIHLVVLVKPSGARCYVDGSEEIGSD------FKIKCEPK 165

Query: 169 -GSPPISYIWYKQQTNNQEP---IKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQ 221
            GS P+ Y W K   + + P   +   T S +  K A    SG+Y CT + +VGS+Q
Sbjct: 166 EGSLPLQYEWQKLSDSQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQ 222


>gi|13376115 adipocyte-specific adhesion molecule [Homo sapiens]
          Length = 373

 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 65/245 (26%), Positives = 106/245 (43%), Gaps = 33/245 (13%)

Query: 1   MGILLGLLLLGHL--TVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLV 58
           M +LL LLL+ +   T+ T+        E VT P    + LP   D L       ++WL+
Sbjct: 1   MSLLLLLLLVSYYVGTLGTHTEIKRVAEEKVTLPCHHQLGLP-EKDTLD------IEWLL 53

Query: 59  --QRGSDPVTIFLRDSSGDHIQQAKYQGRL-HVSHKVPGDVSLQLSTLEMDDRSHYTCEV 115
               G+  V I        +    + +GR+   S+ + GD SLQ+  L+  D   YTC+V
Sbjct: 54  TDNEGNQKVVITYSSRHVYNNLTEEQKGRVAFASNFLAGDASLQIEPLKPSDEGRYTCKV 113

Query: 116 TWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQ-ARGSPPIS 174
                 G  V    I ++ V+    SKP           + +G  ++LQC+ + G+ PI 
Sbjct: 114 ---KNSGRYVWSHVILKVLVRP---SKPKCELEG----ELTEGSDLTLQCESSSGTEPIV 163

Query: 175 YIWYKQQTNNQEPIKVATLSTL--------LFKPAVIADSGSYFCTAKGQVGSEQHSDIV 226
           Y W + +    E  ++   S +        L +   ++ SG Y CTA  + G E  S +V
Sbjct: 164 YYWQRIREKEGEDERLPPKSRIDYNHPGRVLLQNLTMSYSGLYQCTAGNEAGKE--SCVV 221

Query: 227 KFVVK 231
           +  V+
Sbjct: 222 RVTVQ 226


>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
          Length = 398

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 10/124 (8%)

Query: 97  SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
           S+       DD +   C V  ++  G     D+ T  R++ L      +     +     
Sbjct: 193 SVTFQVTREDDGASIVCSVNHESLKG----ADRSTSQRIEVLYTPTAMIRPDPPHP---R 245

Query: 157 QGMRISLQCQARGSP-PISYIWYKQQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKG 215
           +G ++ L C+ RG+P P  Y+W K+   +  P+K+   S L+F     +DSG+Y CTA  
Sbjct: 246 EGQKLLLHCEGRGNPVPQQYLWEKE--GSVPPLKMTQESALIFPFLNKSDSGTYGCTATS 303

Query: 216 QVGS 219
            +GS
Sbjct: 304 NMGS 307



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 12/115 (10%)

Query: 78  QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK 137
           ++A    R+ +    P ++S+ +S + + D   YTC +        +  +  +T L + +
Sbjct: 75  KRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPV---RTAKSLVTVLGIPQ 131

Query: 138 LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYI-WYK-QQTNNQEPIKV 190
               KP +T   GY  ++ +    +L CQ+ GS P + + W K  Q  + EP ++
Sbjct: 132 ----KPIIT---GYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRI 179


>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
          Length = 432

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 10/124 (8%)

Query: 97  SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
           S+       DD +   C V  ++  G     D+ T  R++ L      +     +     
Sbjct: 227 SVTFQVTREDDGASIVCSVNHESLKG----ADRSTSQRIEVLYTPTAMIRPDPPHP---R 279

Query: 157 QGMRISLQCQARGSP-PISYIWYKQQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKG 215
           +G ++ L C+ RG+P P  Y+W K+   +  P+K+   S L+F     +DSG+Y CTA  
Sbjct: 280 EGQKLLLHCEGRGNPVPQQYLWEKE--GSVPPLKMTQESALIFPFLNKSDSGTYGCTATS 337

Query: 216 QVGS 219
            +GS
Sbjct: 338 NMGS 341



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 27/115 (23%), Positives = 54/115 (46%), Gaps = 12/115 (10%)

Query: 78  QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK 137
           ++A    R+ +    P ++S+ +S + + D   YTC +        +  +  +T L + +
Sbjct: 109 KRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPV---RTAKSLVTVLGIPQ 165

Query: 138 LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYI-WYK-QQTNNQEPIKV 190
               KP +T   GY  ++ +    +L CQ+ GS P + + W K  Q  + EP ++
Sbjct: 166 ----KPIIT---GYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRI 213


>gi|157057547 Fc receptor-like 6 [Homo sapiens]
          Length = 434

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 48/135 (35%), Positives = 65/135 (48%), Gaps = 13/135 (9%)

Query: 107 DRSHYTCEVTWQTPDGNQVVRDKIT-ELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQC 165
           D   Y CEV    P+G QV +     E+RVQ   VS+P +T   G        M + L C
Sbjct: 174 DSGLYWCEVA---PEGGQVQKQSPQLEVRVQA-PVSRPVLTLHHGPADPAVGDM-VQLLC 228

Query: 166 QA-RGSPPISYIWYKQQT---NNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQ 221
           +A RGSPPI Y +Y  +    N+  P    T  +LLF      D+G+Y C A+  V S +
Sbjct: 229 EAQRGSPPILYSFYLDEKIVGNHSAPCGGTT--SLLFPVKSEQDAGNYSCEAENSV-SRE 285

Query: 222 HSDIVKFVVKDSSKL 236
            S+  K  +K S  L
Sbjct: 286 RSEPKKLSLKGSQVL 300


>gi|139948432 adlican [Homo sapiens]
          Length = 2828

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 46/192 (23%), Positives = 77/192 (40%), Gaps = 27/192 (14%)

Query: 35   GDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPG 94
            GD+ + C      G     + W +  GS   +    D SG   ++          + V  
Sbjct: 2259 GDLKVDCV---ATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKR----------YVVFN 2305

Query: 95   DVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY-GF 153
            + +L  + + M +   YTC         NQV +D   E+RV+   V+ P       Y   
Sbjct: 2306 NGTLYFNEVGMREEGDYTCFAE------NQVGKD---EMRVRVKVVTAPATIRNKTYLAV 2356

Query: 154  TVPQGMRISLQCQARGSPPISYIWY----KQQTNNQEPIKVATLSTLLFKPAVIADSGSY 209
             VP G  +++ C+A+G P     W     K    + E  ++    TLL + A  +DSG+Y
Sbjct: 2357 QVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNY 2416

Query: 210  FCTAKGQVGSEQ 221
             C  +   G ++
Sbjct: 2417 TCLVRNSAGEDR 2428



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 30/131 (22%), Positives = 55/131 (41%), Gaps = 15/131 (11%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +L +  +++ DR  Y C  +      N    D++  L    ++V +P +        TV 
Sbjct: 1912 TLVIRKVQVQDRGQYMCTAS------NLHGLDRMVVLL--SVTVQQPQILASHYQDVTVY 1963

Query: 157  QGMRISLQCQARGSPPISYIW-------YKQQTNNQEPIKVATLSTLLFKPAVIADSGSY 209
             G  I+++C A+G+P     W       ++  +  +  I +    TL  K A  +D G Y
Sbjct: 1964 LGDTIAMECLAKGTPAPQISWIFPDRRVWQTVSPVEGRITLHENRTLSIKEASFSDRGVY 2023

Query: 210  FCTAKGQVGSE 220
             C A    G++
Sbjct: 2024 KCVASNAAGAD 2034



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 32/131 (24%), Positives = 48/131 (36%), Gaps = 13/131 (9%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +L +  L   D   Y C          + V     +L VQ+ + +   +T  S     V 
Sbjct: 2106 TLYIRNLAPKDSGRYECVAANLVGSARRTV-----QLNVQR-AAANARITGTSPRRTDVR 2159

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEP-------IKVATLSTLLFKPAVIADSGSY 209
             G  + L C A G P    +W        +        IKV    TL+ K     D+G Y
Sbjct: 2160 YGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDY 2219

Query: 210  FCTAKGQVGSE 220
             C A+ +VG +
Sbjct: 2220 LCVARNKVGDD 2230



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 41/168 (24%), Positives = 59/168 (35%), Gaps = 20/168 (11%)

Query: 98  LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
           L++ ++E  D   Y C    +      V R  +     Q     K TVT G   G +V  
Sbjct: 540 LRIKSMEPSDSGLYQCIAQVRDEMDRMVYRVLVQSPSTQP--AEKDTVTIGKNPGESV-- 595

Query: 158 GMRISLQCQARGSPPISYIWYKQQTN------NQEPIKVATLSTLLFKPAVIADSGSYFC 211
               +L C A   P     W            N   + +    TL      ++DSG Y C
Sbjct: 596 ----TLPCNALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRC 651

Query: 212 TAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQ 259
            A  Q G++ H  +   V K  S L   +   P       KA S V++
Sbjct: 652 VAVNQQGAD-HFTVGITVTKKGSGLPSKRGRRPGA-----KALSRVRE 693



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 29/134 (21%), Positives = 46/134 (34%), Gaps = 15/134 (11%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +L +      DR  Y C  +      +  +R  +  L         P +        ++P
Sbjct: 2009 TLSIKEASFSDRGVYKCVASNAAGADSLAIRLHVAAL--------PPVIHQEKLENISLP 2060

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEP-------IKVATLSTLLFKPAVIADSGSY 209
             G+ I + C A+ +P  S  W         P       + V    TL  +     DSG Y
Sbjct: 2061 PGLSIHIHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRY 2120

Query: 210  FCTAKGQVGSEQHS 223
             C A   VGS + +
Sbjct: 2121 ECVAANLVGSARRT 2134



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 22/87 (25%), Positives = 32/87 (36%), Gaps = 7/87 (8%)

Query: 142  KPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTN-------NQEPIKVATLS 194
            KP + T S    +V         C+A G P     W K  T          +  +V    
Sbjct: 1852 KPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLKNG 1911

Query: 195  TLLFKPAVIADSGSYFCTAKGQVGSEQ 221
            TL+ +   + D G Y CTA    G ++
Sbjct: 1912 TLVIRKVQVQDRGQYMCTASNLHGLDR 1938



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 36/163 (22%), Positives = 63/163 (38%), Gaps = 21/163 (12%)

Query: 73   SGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITE 132
            +G H++  +  GR+ +      + +L +    + DR  Y C +  +T  G  V    +  
Sbjct: 2675 NGMHLEGPQTLGRVSLLD----NGTLTVREASVFDRGTYVCRM--ETEYGPSVTSIPVIV 2728

Query: 133  LRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVAT 192
            +       S+PT        +T P G  + L C A G P     W     ++ +    A 
Sbjct: 2729 IAYPPRITSEPTPVI-----YTRP-GNTVKLNCMAMGIPKADITWELPDKSHLKAGVQAR 2782

Query: 193  L---------STLLFKPAVIADSGSYFCTAKGQVGSEQHSDIV 226
            L          +L  + A   D+G Y C AK  +GS+  +  +
Sbjct: 2783 LYGNRFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYI 2825



 Score = 31.2 bits (69), Expect = 1.7
 Identities = 31/146 (21%), Positives = 50/146 (34%), Gaps = 12/146 (8%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY 151
            V G+ SL + +L   D     C    +  +   +++  + E       + KP        
Sbjct: 2497 VHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLILQLTVLE------PMEKPIFHDPISE 2550

Query: 152  GFTVPQGMRISLQCQARGSPPISYIWY------KQQTNNQEPIKVATLSTLLFKPAVIAD 205
              T   G  ISL C A G+P  S +W        Q     +         L        D
Sbjct: 2551 KITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVD 2610

Query: 206  SGSYFCTAKGQVGSEQHSDIVKFVVK 231
            +G+Y C A+   G  +    +K  +K
Sbjct: 2611 AGAYRCVARNAAGHTERLVSLKVGLK 2636


>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
          Length = 4391

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 41/146 (28%), Positives = 65/146 (44%), Gaps = 14/146 (9%)

Query: 77   IQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQ 136
            I  +K +  L   H++ GD +L +  +   D   Y C  T  +P G+     + T +   
Sbjct: 3243 IHWSKLRSPLPWQHRLEGD-TLIIPRVAQQDSGQYICNAT--SPAGHA----EATII--- 3292

Query: 137  KLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTL 196
             L V  P   T      +V  G  + LQC A G+PP+++ W   +  +  P +    + L
Sbjct: 3293 -LHVESPPYATTVPEHASVQAGETVQLQCLAHGTPPLTFQW--SRVGSSLPGRATARNEL 3349

Query: 197  L-FKPAVIADSGSYFCTAKGQVGSEQ 221
            L F+ A   DSG Y C    +VGS +
Sbjct: 3350 LHFERAAPEDSGRYRCRVTNKVGSAE 3375



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 38/140 (27%), Positives = 58/140 (41%), Gaps = 11/140 (7%)

Query: 84   GRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKP 143
            G+L    ++ G + L+L  +E  D++ Y C     +  G QV R     L V      + 
Sbjct: 1905 GQLPAKAQIHGGI-LRLPAVEPTDQAQYLCRA--HSSAGQQVAR---AVLHVHGGGGPRV 1958

Query: 144  TVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTN--NQEPIKVATLSTLLFKPA 201
             V   S     V  G  + L C+A G P  +  W K+  +   Q   +   ++TLL    
Sbjct: 1959 QV---SPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAI 2015

Query: 202  VIADSGSYFCTAKGQVGSEQ 221
              AD+G Y C A    G+ Q
Sbjct: 2016 TTADAGFYLCVATSPAGTAQ 2035



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 48/186 (25%), Positives = 75/186 (40%), Gaps = 13/186 (6%)

Query: 81   KYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQ--TPDGNQVVR-DKITELRVQK 137
            K  G L   H+V G + L+L+ +   D   Y+C+VT    T + + +V  +  +   +  
Sbjct: 2862 KRGGNLPARHQVHGPL-LRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPA 2920

Query: 138  LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL 197
              +++P     S    T  +G  + L C   G       WYK+      P +  T  + L
Sbjct: 2921 PGLAQPIYIEASSSHVT--EGQTLDLNCVVPGQAHAQVTWYKR--GGSLPARHQTHGSQL 2976

Query: 198  FKPAVI-ADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATST 256
                V  ADSG Y C A    G EQ +     V    S+    +  +P     P   +ST
Sbjct: 2977 RLHLVSPADSGEYVCRAASGPGPEQEASFT--VTVPPSEGSSYRLRSPVISIDP--PSST 3032

Query: 257  VKQSWD 262
            V+Q  D
Sbjct: 3033 VQQGQD 3038



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 23/65 (35%), Positives = 32/65 (49%), Gaps = 8/65 (12%)

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL-----STLLFKPAVIADSGSY 209
            VPQG   SL+CQ  GSPP  + W ++   +  P+   T      S L F     +D+G Y
Sbjct: 1688 VPQGGSHSLRCQVSGSPPHYFYWSRE---DGRPVPSGTQQRHQGSELHFPSVQPSDAGVY 1744

Query: 210  FCTAK 214
             CT +
Sbjct: 1745 ICTCR 1749



 Score = 37.0 bits (84), Expect = 0.031
 Identities = 47/181 (25%), Positives = 70/181 (38%), Gaps = 24/181 (13%)

Query: 81   KYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSV 140
            K  G L   H+V G   L+L  +   D   Y C V   +  G Q     +T    Q+LS 
Sbjct: 2472 KRGGSLPARHQVHGS-RLRLLQVTPADSGEYVCRVVGSS--GTQEASVLVTIQ--QRLSG 2526

Query: 141  SKPTVTTGSGY-------GFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL 193
            S    + G  Y         ++  G  + L C      P +  WYK+      P +   +
Sbjct: 2527 SH---SQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKR--GGSLPSRHQIV 2581

Query: 194  STLLFKPAVI-ADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKL------LKTKTEAPTT 246
             + L  P V  ADSG Y C      GS + S IV      SS +      ++ ++ +PT 
Sbjct: 2582 GSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTV 2641

Query: 247  M 247
            +
Sbjct: 2642 V 2642



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 45/199 (22%), Positives = 74/199 (37%), Gaps = 12/199 (6%)

Query: 74   GDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITEL 133
            G  ++  K  G+L   H V   V L++  L+   +  Y C+       G         +L
Sbjct: 3428 GTQLRWFKEGGQLPPGHSVQDGV-LRIQNLDQSCQGTYICQA-----HGPWGKAQASAQL 3481

Query: 134  RVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL 193
             +Q L      + T      TV  G  +  +C A G P     W K    +  P  V + 
Sbjct: 3482 VIQALPSVLINIRTSVQ---TVVVGHAVEFECLALGDPKPQVTWSKVG-GHLRPGIVQSG 3537

Query: 194  STLLFKPAVIADSGSYFCTAKGQVGSEQ-HSDIVKFVVKDSSKLLKTKTEAPTTMTYPLK 252
              +      +AD+G Y CTA    G+ Q H  ++   +   S   + +  A +   +P  
Sbjct: 3538 GVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQALPQISMPQEVRVPAGSAAVFPCI 3597

Query: 253  ATSTVKQSWDWTTDMDGYL 271
            A+        W + +DG L
Sbjct: 3598 ASGYPTPDISW-SKLDGSL 3615



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 41/149 (27%), Positives = 58/149 (38%), Gaps = 9/149 (6%)

Query: 81   KYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITEL-RVQKLS 139
            K  G L V H+  G + L+L      D   Y C V   +      V   I     V  L 
Sbjct: 2376 KRGGSLPVRHQTHGSL-LRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALG 2434

Query: 140  VSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTN--NQEPIKVATLSTLL 197
            V+ PTV   S     V +G  + L C   G       W+K+  +   +  +  + L  L 
Sbjct: 2435 VT-PTVRIESSSS-QVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPARHQVHGSRLRLLQ 2492

Query: 198  FKPAVIADSGSYFCTAKGQVGSEQHSDIV 226
              PA   DSG Y C   G  G+++ S +V
Sbjct: 2493 VTPA---DSGEYVCRVVGSSGTQEASVLV 2518



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 37/153 (24%), Positives = 62/153 (40%), Gaps = 12/153 (7%)

Query: 141  SKP-TVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL-F 198
            SKP TVT       +V  G  ++  C A+   P   + + +  N + P +    + +L  
Sbjct: 1768 SKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTI 1827

Query: 199  KPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVK 258
            +   ++D+G+Y CT       +Q +  +   V+ S  L      AP    +P + T    
Sbjct: 1828 RNVQLSDAGTYVCTGSNMFAMDQGTATLH--VQASGTL-----SAPVVSIHPPQLTVQPG 1880

Query: 259  QSWDWTTDMDGYLGET---SAGPGKSLPVFAII 288
            Q  ++     G    T   + GPG  LP  A I
Sbjct: 1881 QLAEFRCSATGSPTPTLEWTGGPGGQLPAKAQI 1913



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 30/127 (23%), Positives = 47/127 (37%), Gaps = 6/127 (4%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +L +  +   D   Y C  T  +P G    R ++  L     S     + + S    +V 
Sbjct: 2009 TLLIPAITTADAGFYLCVAT--SPAGTAQARIQVVVLSASDASPPPVKIESSSP---SVT 2063

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQ 216
            +G  + L C   GS      WY+ +  +  P      S L       ADSG Y C  +  
Sbjct: 2064 EGQTLDLNCVVAGSAHAQVTWYR-RGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVENG 2122

Query: 217  VGSEQHS 223
             G ++ S
Sbjct: 2123 SGPKEAS 2129



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 32/133 (24%), Positives = 49/133 (36%), Gaps = 6/133 (4%)

Query: 81   KYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSV 140
            K  G L   H+  G + L+L  +   D   Y C V   +     +    +  +    +  
Sbjct: 2187 KRGGSLPARHQTHGSL-LRLHQVTPADSGEYVCHVVGTS---GPLEASVLVTIEASVIPG 2242

Query: 141  SKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKP 200
              P V   S    TV +G  + L C   G       WYK+  +     +V      +F+ 
Sbjct: 2243 PIPPVRIESSSS-TVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQVRGSRLYIFQ- 2300

Query: 201  AVIADSGSYFCTA 213
            A  AD+G Y C A
Sbjct: 2301 ASPADAGQYVCRA 2313



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 21/74 (28%), Positives = 31/74 (41%), Gaps = 3/74 (4%)

Query: 154  TVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL-STLLFKPAVIADSGSYFCT 212
            TV +G  + L C     P     WYK+      P +  T  S L      +ADSG Y C 
Sbjct: 2640 TVVEGQTLDLNCVVARQPQAIITWYKR--GGSLPSRHQTHGSHLRLHQMSVADSGEYVCR 2697

Query: 213  AKGQVGSEQHSDIV 226
            A   + + + S ++
Sbjct: 2698 ANNNIDALEASIVI 2711



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 32/125 (25%), Positives = 42/125 (33%), Gaps = 9/125 (7%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITE-LRVQKLSVSKPTVTTGSGYGFTVP 156
            L +  +++ D   Y C         N    D+ T  L VQ        V +      TV 
Sbjct: 1825 LTIRNVQLSDAGTYVCT------GSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQLTVQ 1878

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAV-IADSGSYFCTAKG 215
             G     +C A GSP  +  W       Q P K      +L  PAV   D   Y C A  
Sbjct: 1879 PGQLAEFRCSATGSPTPTLEW-TGGPGGQLPAKAQIHGGILRLPAVEPTDQAQYLCRAHS 1937

Query: 216  QVGSE 220
              G +
Sbjct: 1938 SAGQQ 1942



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 21/73 (28%), Positives = 32/73 (43%), Gaps = 1/73 (1%)

Query: 154  TVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTA 213
            TV  G   +L+C A GSP  +  W K ++      ++    TL+       DSG Y C A
Sbjct: 3222 TVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQHRLEG-DTLIIPRVAQQDSGQYICNA 3280

Query: 214  KGQVGSEQHSDIV 226
                G  + + I+
Sbjct: 3281 TSPAGHAEATIIL 3293



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 22/73 (30%), Positives = 30/73 (41%), Gaps = 3/73 (4%)

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI-ADSGSYFCTA 213
            V +G  + L C   G       W+K+      P +  T  +LL    V  ADSG Y C  
Sbjct: 2163 VAEGQTLDLNCVVPGQAHAQVTWHKR--GGSLPARHQTHGSLLRLHQVTPADSGEYVCHV 2220

Query: 214  KGQVGSEQHSDIV 226
             G  G  + S +V
Sbjct: 2221 VGTSGPLEASVLV 2233



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 38/166 (22%), Positives = 54/166 (32%), Gaps = 26/166 (15%)

Query: 81   KYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSV 140
            K  G L   H+  G   L+L  + + D   Y C              + I  L    +  
Sbjct: 2665 KRGGSLPSRHQTHGS-HLRLHQMSVADSGEYVCRAN-----------NNIDALEASIVIS 2712

Query: 141  SKPTVTTGSGYGFTVP-----------QGMRISLQCQARGSPPISYIWYKQQTNNQEPIK 189
              P+  + S  G ++P           +G  + L C   G       W+K+      P  
Sbjct: 2713 VSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKR--GGSLPSH 2770

Query: 190  VATL-STLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSS 234
              T  S L       ADSG Y C   G  G  + S +V      SS
Sbjct: 2771 HQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTIEASGSS 2816



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 21/73 (28%), Positives = 30/73 (41%), Gaps = 3/73 (4%)

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL-FKPAVIADSGSYFCTA 213
            V +G  + L+C   G       W+K+  N   P +      LL       ADSG Y C  
Sbjct: 2838 VAEGQTLDLKCVVPGQAHAQVTWHKRGGN--LPARHQVHGPLLRLNQVSPADSGEYSCQV 2895

Query: 214  KGQVGSEQHSDIV 226
             G  G+ + S +V
Sbjct: 2896 TGSSGTLEASVLV 2908



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 12/96 (12%)

Query: 135  VQKLSV-SKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVA-- 191
            V  LSV   PTV+        V  G  ++L+C + G P  S  W +  +    P K+   
Sbjct: 3103 VVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISST---PAKLEQR 3159

Query: 192  ------TLSTLLFKPAVIADSGSYFCTAKGQVGSEQ 221
                  + + L    A  +D+G+Y C A+  +G+ Q
Sbjct: 3160 TYGLMDSHAVLQISSAKPSDAGTYVCLAQNALGTAQ 3195



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 40/150 (26%), Positives = 58/150 (38%), Gaps = 23/150 (15%)

Query: 90   HKVPGDVS----LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKL-SVSKPT 144
            H  PG V     ++++ +E+ D   Y C  T         V      L VQ L  +S P 
Sbjct: 3528 HLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVL-----LLVQALPQISMPQ 3582

Query: 145  VTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIA 204
                      VP G      C A G P     W K   +   P      + +L  P+V  
Sbjct: 3583 EVR-------VPAGSAAVFPCIASGYPTPDISWSK--LDGSLPPDSRLENNMLMLPSVRP 3633

Query: 205  -DSGSYFCTA---KGQVGSEQHSDIVKFVV 230
             D+G+Y CTA   +G+V +  H  + + VV
Sbjct: 3634 QDAGTYVCTATNRQGKVKAFAHLQVPERVV 3663


>gi|109150416 peroxidasin [Homo sapiens]
          Length = 1479

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 42/174 (24%), Positives = 70/174 (40%), Gaps = 15/174 (8%)

Query: 90  HKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGS 149
           H V    +L++S + + D+  Y C+         +VV     + RV  +  S P+ TT  
Sbjct: 479 HLVLSSGTLRISGVALHDQGQYECQAV-NIIGSQKVVAHLTVQPRVTPVFASIPSDTT-- 535

Query: 150 GYGFTVPQGMRISLQCQARGSPPISYIWYKQ--QTNNQEPIKVATLSTLLFKPAVIADSG 207
                V  G  + L C ++G P  +  W K   Q        ++    L       AD+G
Sbjct: 536 -----VEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPADAG 590

Query: 208 SYFCTAKGQVGSEQHSDIVKFVVKDSSK-----LLKTKTEAPTTMTYPLKATST 256
            Y C A+  +GS   S ++   V D S+     +  +  EA  T+   + +T T
Sbjct: 591 RYECVARNTIGSASVSMVLSVNVPDVSRNGDPFVATSIVEAIATVDRAINSTRT 644



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 2/69 (2%)

Query: 155 VPQGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLLFKPAVIADSGSYFCT 212
           V +G  +  QC+A+G+PP    W K   Q +      V +  TL      + D G Y C 
Sbjct: 444 VIEGQTVDFQCEAKGNPPPVIAWTKGGSQLSVDRRHLVLSSGTLRISGVALHDQGQYECQ 503

Query: 213 AKGQVGSEQ 221
           A   +GS++
Sbjct: 504 AVNIIGSQK 512



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 35/165 (21%), Positives = 64/165 (38%), Gaps = 30/165 (18%)

Query: 88  VSHKVPGDVSL--QLSTLEMDDRS-HYTCEVTW-------QTPDGN-----------QVV 126
           ++H VPG  +    +  L +D  + H  CE+ W           GN           ++ 
Sbjct: 170 ITHLVPGTFNHLESMKRLRLDSNTLHCDCEILWLADLLKTYAESGNAQAAAICEYPRRIQ 229

Query: 127 RDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQE 186
              +  +  ++L+  +P +T+       V  G  +   C+A G+P    IW +   NN+ 
Sbjct: 230 GRSVATITPEELNCERPRITS-EPQDADVTSGNTVYFTCRAEGNPKPEIIWLR--NNNEL 286

Query: 187 PIKVATL------STLLFKPAVIADSGSYFCTAKGQVGSEQHSDI 225
            +K  +        TL+ +     D G Y C AK   G  +  ++
Sbjct: 287 SMKTDSRLNLLDDGTLMIQNTQETDQGIYQCMAKNVAGEVKTQEV 331



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 17/65 (26%), Positives = 26/65 (40%), Gaps = 3/65 (4%)

Query: 158 GMRISLQCQARGSPPISYIWYKQQTNN---QEPIKVATLSTLLFKPAVIADSGSYFCTAK 214
           G  ++L+C A G PP    W +           + +     L  +  V  DSG Y C+A 
Sbjct: 356 GESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSAT 415

Query: 215 GQVGS 219
             + S
Sbjct: 416 NNIDS 420


>gi|189571583 intercellular adhesion molecule 5 precursor [Homo
           sapiens]
          Length = 924

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 40/129 (31%), Positives = 59/129 (45%), Gaps = 14/129 (10%)

Query: 92  VPGD-VSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGS- 149
           VPG    LQL+  E DDR  + C+ T    DG  +++++  ELRV    +  P +     
Sbjct: 361 VPGQPAQLQLNATENDDRRSFFCDATLDV-DGETLIKNRSAELRV----LYAPRLDDSDC 415

Query: 150 GYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIADSGSY 209
              +T P+G   +L+C+ARG+P  S    +           A L+  L  P   A SG+Y
Sbjct: 416 PRSWTWPEGPEQTLRCEARGNPEPSVHCARSDGG-------AVLALGLLGPVTRALSGTY 468

Query: 210 FCTAKGQVG 218
            C A    G
Sbjct: 469 RCKAANDQG 477


>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
          Length = 355

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 43/159 (27%), Positives = 72/159 (45%), Gaps = 23/159 (14%)

Query: 87  HVSHKVPGDVS----LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSK 142
           H+S K  G VS    L++  +  +    Y C  +      N V    +  ++V   +V+ 
Sbjct: 171 HISPKAVGFVSEDEYLEIQGITREQSGDYECSAS------NDVAAPVVRRVKV---TVNY 221

Query: 143 PT-VTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVAT---LST 195
           P  ++   G G  VP G + +LQC+A   P   + WYK        ++ +KV     LS 
Sbjct: 222 PPYISEAKGTG--VPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSK 279

Query: 196 LLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSS 234
           L+F      D G+Y C A  ++G   ++ I+ F VK ++
Sbjct: 280 LIFFNVSEHDYGNYTCVASNKLG-HTNASIMLFEVKTTA 317



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 35/126 (27%), Positives = 52/126 (41%), Gaps = 18/126 (14%)

Query: 97  SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
           S+++  +++ D   YTC V  QT +  +  R     L VQ   VS   V   S    ++ 
Sbjct: 99  SIEIQNVDVYDEGPYTCSV--QTDNHPKTSR---VHLIVQ---VSPKIVEISSD--ISIN 148

Query: 157 QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST---LLFKPAVIADSGSYFCTA 213
           +G  ISL C A G P  +  W      +  P  V  +S    L  +      SG Y C+A
Sbjct: 149 EGNNISLTCIATGRPEPTVTW-----RHISPKAVGFVSEDEYLEIQGITREQSGDYECSA 203

Query: 214 KGQVGS 219
              V +
Sbjct: 204 SNDVAA 209


>gi|30102948 hyaluronan and proteoglycan link protein 3 [Homo
           sapiens]
          Length = 360

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 46/151 (30%), Positives = 68/151 (45%), Gaps = 24/151 (15%)

Query: 22  ILEVPESVTGPWKG-DVNLPCTY---DPLQGYTQVLVKW--LVQRGSDP----VTIFLRD 71
           ++E PE     ++G  V LPC Y     L    +V VKW  L + G+      V I LR 
Sbjct: 50  VVETPEETLFTYQGASVILPCRYRYEPALVSPRRVRVKWWKLSENGAPEKDVLVAIGLRH 109

Query: 72  SS-GDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKI 130
            S GD      YQGR+H+      DVSL++  L ++D   Y CEV     DG   + D+ 
Sbjct: 110 RSFGD------YQGRVHLRQDKEHDVSLEIQDLRLEDYGRYRCEVI----DG---LEDES 156

Query: 131 TELRVQKLSVSKPTVTTGSGYGFTVPQGMRI 161
             + ++   V  P  +    Y F   +G ++
Sbjct: 157 GLVELELRGVVFPYQSPNGRYQFNFHEGQQV 187


>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3783

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 36/132 (27%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY 151
            +PG   LQ+   + +D   YTC VT +   G  V    +  L    +S   P    G   
Sbjct: 1309 LPGTHGLQILNAQKEDAGQYTCVVTNEL--GEAVKNYHVEVLIPPSISKDDPLAEVGVKE 1366

Query: 152  GFTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLL-FKPAVIADSGS 208
              T      ++L+C++   PP +  WYK  Q       ++V     LL  +P  ++DSG 
Sbjct: 1367 VKT-KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 1425

Query: 209  YFCTAKGQVGSE 220
            Y C A    G +
Sbjct: 1426 YLCVATNVAGED 1437



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 61/248 (24%), Positives = 90/248 (36%), Gaps = 33/248 (13%)

Query: 23  LEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQAKY 82
           + VP  +T P       P    P+   T V +         P  ++L+D  G+ +  A  
Sbjct: 691 VNVPPRITLP-------PSLPGPVLVNTPVRLTCNATGAPSPTLMWLKD--GNPVSPAGT 741

Query: 83  QGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSK 142
            G L V    PG   L L++    D   Y+C       +  Q V           L V  
Sbjct: 742 PG-LQV---FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDV----------VLQVHM 787

Query: 143 PTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST----LLF 198
           P    G     +V     ++L+CQ+   PP    W+K      EP     LS     L  
Sbjct: 788 PPSILGEELNVSVVANESVALECQSHAMPPPVLSWWK-DGRPLEPRPGVHLSADKALLQV 846

Query: 199 KPAVIADSGSYFCTAKGQVG-SEQHSDIVKFVVK----DSSKLLKTKTEAPTTMTYPLKA 253
             A + D+G Y C A  Q G SE+H ++  +V        S  L  +   PT ++   + 
Sbjct: 847 DRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTRLSCECRG 906

Query: 254 TSTVKQSW 261
               K SW
Sbjct: 907 VPFPKISW 914



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 44/179 (24%), Positives = 68/179 (37%), Gaps = 26/179 (14%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELR---VQKLSVSKPTVTTGSGYGFT 154
            LQLS L+      YTC           V  +   E R   V  + V+    ++G      
Sbjct: 1898 LQLSRLQPAQAGTYTC-----------VAENTQAEARKDFVVAVLVAPRIRSSGVAREHH 1946

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQT---NNQEPIKVATL--STLLFKPAVIADSGSY 209
            V +G  + L C+A G PP    W K  +    +  P     L   +L+ K    +D+G+Y
Sbjct: 1947 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 2006

Query: 210  FCTAKGQVGSEQHSDIVKFVV-------KDSSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
             C A    G +     V  +V        D S  L ++     TM  P++ +  +  SW
Sbjct: 2007 TCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSW 2065



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 13/127 (10%)

Query: 98  LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
           LQ+  +++ D   YTC  T    +  + V  K+         +  P +  G      V +
Sbjct: 568 LQIEKVDLRDEGIYTCAATNLAGESKREVALKV---------LVPPNIEPGP-VNKAVLE 617

Query: 158 GMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLL-FKPAVIADSGSYFCTAK 214
              ++L+C A G PP    W+K  Q  ++   + V+    +L  + A ++D+GSY C A 
Sbjct: 618 NASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVAS 677

Query: 215 GQVGSEQ 221
              GS +
Sbjct: 678 NVAGSTE 684



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 12/127 (9%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQ+ST E+ D + Y C    Q         +K+  LRVQ      P +        T   
Sbjct: 1619 LQVSTAEVADAASYMCVAENQAGSA-----EKLFTLRVQV----PPRIAGLDLEQVTAIL 1669

Query: 158  GMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVATLSTLLFKPAVIADSGSYFCTAK 214
               +SL C     P     WYK     +  +E   +    TL    A ++DSG Y C A 
Sbjct: 1670 NSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEAL 1729

Query: 215  GQVGSEQ 221
               G +Q
Sbjct: 1730 NAAGRDQ 1736



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 16/128 (12%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVS-KPTVTTGS-GYGFT 154
            SL L  L   D   YTC      P G         + R+  ++V   PT+  G+ G G  
Sbjct: 1992 SLVLKGLRASDAGAYTCVA--HNPAGE--------DARLHTVNVLVPPTIKQGADGSGTL 2041

Query: 155  VPQ-GMRISLQCQARGSPPISYIWYKQQTN---NQEPIKVATLSTLLFKPAVIADSGSYF 210
            V + G  +++ C  RGSPPI   W K       +Q  +   +  TL      +AD+G + 
Sbjct: 2042 VSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFT 2101

Query: 211  CTAKGQVG 218
            C A    G
Sbjct: 2102 CVAASPAG 2109



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 17/131 (12%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGF---- 153
            LQ+  +  ++   Y+C+ +      N+V  D +      +L V  P V  G         
Sbjct: 1524 LQIPLVRAENAGRYSCKAS------NEVGEDWLH----YELLVLTPPVILGDTEELVEEV 1573

Query: 154  TVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYF 210
            TV     +SLQC A G+P  +  W +         ++  L     L    A +AD+ SY 
Sbjct: 1574 TVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYM 1633

Query: 211  CTAKGQVGSEQ 221
            C A+ Q GS +
Sbjct: 1634 CVAENQAGSAE 1644



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +L++S +++ D   +TC     +P G   V D+   L+VQ   V +P           V 
Sbjct: 2086 TLRISKVQLADAGIFTCVAA--SPAG---VADRNFTLQVQVPPVLEPVEFQND---VVVV 2137

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYFCTA 213
            +G  + L C+ARG P     W K    + EP+   +L    +L  +     DSG+Y C A
Sbjct: 2138 RGSLVELPCEARGVPLPLVSWMK----DGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVA 2193

Query: 214  KGQVG 218
              + G
Sbjct: 2194 VSEAG 2198



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 46/200 (23%), Positives = 73/200 (36%), Gaps = 21/200 (10%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQL  L   D   Y+C  T +   G+  V  ++    V  +    P V         +P 
Sbjct: 2355 LQLQALSTADSGDYSC--TARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLP- 2411

Query: 158  GMRISLQCQARGSPPISYIWYKQQT--NNQEP-IKVATLSTLLFKPAVIADSGSYFCTAK 214
                   CQA G P     W K +   + + P  ++    +L  +P +  D+G Y C A 
Sbjct: 2412 -------CQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLAS 2464

Query: 215  GQVGSEQHSDIVKF-----VVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTDMDG 269
               GS++    ++      +    S L  T   A T    P +A+ + K    W  D   
Sbjct: 2465 NSAGSDRQGRDLRVLEPPAIAPSPSNLTLT---AHTPALLPCEASGSPKPLVVWWKDGQK 2521

Query: 270  YLGETSAGPGKSLPVFAIIL 289
                   G  + LP  A++L
Sbjct: 2522 LDFRLQQGAYRLLPSNALLL 2541



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 13/135 (9%)

Query: 87   HVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVT 146
            H+ H++    SL +   E DD   Y C       +    V  K+  L +Q   V +    
Sbjct: 2981 HLRHQLQNG-SLTIRRTERDDAGRYQC-----LAENEMGVAKKVVILVLQSAPVFQV--- 3031

Query: 147  TGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--STLLFKPAVIA 204
                   TV  G  ++L+CQA G P  +  W +     +   ++ TL   +L  +     
Sbjct: 3032 --EPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETG 3089

Query: 205  DSGSYFCTAKGQVGS 219
            D+G+Y C A   +GS
Sbjct: 3090 DAGTYDCVAHNLLGS 3104



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 39/125 (31%), Positives = 52/125 (41%), Gaps = 11/125 (8%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L +  LE  D   YTC         N V R +    RV    +  P  TT  G   ++  
Sbjct: 2811 LLVKNLEGQDAGTYTCTAE------NAVGRAR---RRVHLTILVLPVFTTLPG-DRSLRL 2860

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIA-DSGSYFCTAKGQ 216
            G R+ L+C ARGSP     W        E +      + L + AV   DSG+Y C A+ +
Sbjct: 2861 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 2920

Query: 217  VGSEQ 221
            VG  Q
Sbjct: 2921 VGRTQ 2925



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 137  KLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQE-PIKVATL 193
            +L V  P V        +  +G    L C+ARGSP  +  W K  Q  +  E    +   
Sbjct: 2749 RLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPS 2808

Query: 194  STLLFKPAVIADSGSYFCTAKGQVG 218
              LL K     D+G+Y CTA+  VG
Sbjct: 2809 GELLVKNLEGQDAGTYTCTAENAVG 2833



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 39/161 (24%), Positives = 62/161 (38%), Gaps = 25/161 (15%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKP----TVTT 147
            +PG  +LQL    + D   YTCE        N   RD+    ++ +LSV  P        
Sbjct: 1705 LPGTHTLQLGRARLSDSGMYTCEAL------NAAGRDQ----KLVQLSVLVPPAFRQAPR 1754

Query: 148  GSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL-------FKP 200
            G      V  G +  L C+    P  +  WYK    + +P+ +A  +  L        + 
Sbjct: 1755 GPQDAVLVRVGDKAVLSCETDALPEPTVTWYK----DGQPLVLAQRTQALRGGQRLEIQE 1810

Query: 201  AVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKT 241
            A ++D G Y C      G    +  +   V  + +  KT+T
Sbjct: 1811 AQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTET 1851



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 36/131 (27%), Positives = 50/131 (38%), Gaps = 16/131 (12%)

Query: 94  GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQV-VRDKITELRVQKLSVSKPTVTTGSGYG 152
           G   LQL   +  D   YTC+ +      N V   +K T L V       PT+    G  
Sbjct: 272 GGRQLQLGRAQSSDAGVYTCKAS------NAVGAAEKATRLDVYV----PPTIEGAGGRP 321

Query: 153 FTVPQ--GMRISLQCQARGSPPISYIWYKQ---QTNNQEPIKVATLSTLLFKPAVIADSG 207
           + V    G  ++L+C ARG P  +  W+ +      + E       S L  +    A SG
Sbjct: 322 YVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSG 381

Query: 208 SYFCTAKGQVG 218
            Y C A    G
Sbjct: 382 LYSCVASSPAG 392



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 40/148 (27%), Positives = 61/148 (41%), Gaps = 14/148 (9%)

Query: 78  QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK 137
           +Q    G  H+  +  G V L+++   + D   Y C     +P G Q  RD   +LRV  
Sbjct: 164 RQPVLPGGPHLQVQEDGQV-LRITGSHVGDEGRYQCVAF--SPAGQQA-RD--FQLRVH- 216

Query: 138 LSVSKPTVTTGSGYG-FTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--- 193
              + PT+   +  G   V +   + L C+ARG P  +  W+K         KV      
Sbjct: 217 ---APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGG 273

Query: 194 STLLFKPAVIADSGSYFCTAKGQVGSEQ 221
             L    A  +D+G Y C A   VG+ +
Sbjct: 274 RQLQLGRAQSSDAGVYTCKASNAVGAAE 301



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 34/132 (25%), Positives = 53/132 (40%), Gaps = 21/132 (15%)

Query: 94   GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGF 153
            G  +LQ + +  +D   Y C   W     N+V R +     V  + V +  V  G  + +
Sbjct: 2896 GGSTLQRAAVSREDSGTYVC---WAE---NRVGRTQA----VSFVHVKEAPVLQGEAFSY 2945

Query: 154  TV-PQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL------STLLFKPAVIADS 206
             V P G  I L C  RG P     W K       P++ + L       +L  +     D+
Sbjct: 2946 LVEPVGGSIQLDCVVRGDPVPDIHWIKDGL----PLRGSHLRHQLQNGSLTIRRTERDDA 3001

Query: 207  GSYFCTAKGQVG 218
            G Y C A+ ++G
Sbjct: 3002 GRYQCLAENEMG 3013



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 34/131 (25%), Positives = 50/131 (38%), Gaps = 22/131 (16%)

Query: 98  LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
           LQ+   ++ D  HYTCE   Q         +K   L V       P       +  TV +
Sbjct: 844 LQVDRADVWDAGHYTCEALNQAGHS-----EKHYNLNVWVA----PVFPLRESHTLTVRE 894

Query: 158 GMRISLQCQARGSPPISYIWYKQQTNNQEPI--------KVATLSTLLF-KPAVIADSGS 208
           G    L C+ RG P     W K    + +P+         V+ +  LL+   A +A  G+
Sbjct: 895 GHPTRLSCECRGVPFPKISWRK----DGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 950

Query: 209 YFCTAKGQVGS 219
           Y C     VG+
Sbjct: 951 YTCECSNVVGN 961



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 32/131 (24%), Positives = 49/131 (37%), Gaps = 7/131 (5%)

Query: 161  ISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--STLLFKPAVIADSGSYFCTAKGQVG 218
            + L C+A G P  +  W K+  N    +    L    L    A   D+G+Y C AK   G
Sbjct: 2683 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG 2742

Query: 219  SEQHSD--IVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTD---MDGYLGE 273
            S       +V+      + L    T   +    P KA  + + +  W  D   + G  G+
Sbjct: 2743 SAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGK 2802

Query: 274  TSAGPGKSLPV 284
             +  P   L V
Sbjct: 2803 FTIQPSGELLV 2813



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 31/135 (22%), Positives = 52/135 (38%), Gaps = 28/135 (20%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYG--FT 154
            SLQL  +   D   Y+C    +  +            R  +L+V +P     SG     +
Sbjct: 2175 SLQLEAVGAGDSGTYSCVAVSEAGEAR----------RHFQLTVMEPPHIEDSGQPTELS 2224

Query: 155  VPQGMRISLQCQARGSPPISYIWYK------QQTNNQEPIKVATLSTLLFKPAVIADSGS 208
            +  G  + L C A+G+P  +  W+K      +  NN    +V            + D+G 
Sbjct: 2225 LTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLR----------VRDAGL 2274

Query: 209  YFCTAKGQVGSEQHS 223
            Y C A+   G+ + S
Sbjct: 2275 YTCLAESPAGAIEKS 2289



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 13/113 (11%)

Query: 111 YTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYG-FTVPQGMRISLQCQARG 169
           Y+C  +  +P G  V++  + E++V       P +    G G  T   G  + L CQA G
Sbjct: 383 YSCVAS--SPAGEAVLQYSV-EVQVP------PQLLVAEGLGQVTTIVGQPLELPCQASG 433

Query: 170 SPPISYIWYKQQTNNQE--PIKVATLSTLLFKPAVIAD-SGSYFCTAKGQVGS 219
           SP  +  W +     +E   ++VA+  T L    V  D SG + C A  + G+
Sbjct: 434 SPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGT 486



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 11/80 (13%)

Query: 161  ISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI-------ADSGSYFCTA 213
            ++L C+A G PP +  W++     +EP+     + LL    ++        DSG Y C A
Sbjct: 1088 LTLLCEAMGIPPPAIRWFR----GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1143

Query: 214  KGQVGSEQHSDIVKFVVKDS 233
              + G  + +  V+ +V  S
Sbjct: 1144 SNEAGEARRNFSVEVLVPPS 1163



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 29/129 (22%)

Query: 103  LEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGM-RI 161
            L + D   YTC    ++P G     +K   +RVQ    + P +    G  F V     ++
Sbjct: 2267 LRVRDAGLYTCLA--ESPAG---AIEKSFRVRVQ----APPNIVGPRGPRFVVGLAPGQL 2317

Query: 162  SLQCQARGSPPISYIWYK------QQTNNQEP-----IKVATLSTLLFKPAVIADSGSYF 210
             L+C     P     W++      +  + Q P     +++  LST        ADSG Y 
Sbjct: 2318 VLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST--------ADSGDYS 2369

Query: 211  CTAKGQVGS 219
            CTA+   GS
Sbjct: 2370 CTARNAAGS 2378



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 125  VVRDKITEL-RVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK---Q 180
            VV +++ E  R+ +++V  P         FTV     + L C + G P  +  W K   Q
Sbjct: 2555 VVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 2614

Query: 181  QTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVG 218
                    +V+    L    A+   +G Y C+A+   G
Sbjct: 2615 LGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 2652



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 163  LQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLLFKPAVIAD-SGSYFCTAKGQVGS 219
            L C     PP    WY+  Q  +  + + V     +L  P V A+ +G Y C A  +VG 
Sbjct: 1488 LYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGE 1547

Query: 220  E 220
            +
Sbjct: 1548 D 1548


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 40/137 (29%), Positives = 55/137 (40%), Gaps = 12/137 (8%)

Query: 89   SHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTG 148
            +H V     LQ+S    +D   Y C    Q P G        T L   KL+V  P V + 
Sbjct: 4034 NHAVLPSGGLQISRAVREDAGTYMCVA--QNPAG--------TALGKIKLNVQVPPVISP 4083

Query: 149  SGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI--ADS 206
                + +     I+L C+A G PP    W+K      E I+   LS+   + A +   D+
Sbjct: 4084 HLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDA 4143

Query: 207  GSYFCTAKGQVGSEQHS 223
            G Y C A    GS   S
Sbjct: 4144 GHYTCMAANVAGSSSTS 4160



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 37/138 (26%), Positives = 55/138 (39%), Gaps = 21/138 (15%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQ------VVRDKITELRVQKLSVSKPTV 145
            VPG  +LQ+   ++ D   YTC    Q  +  +       V   I +   + LSV     
Sbjct: 3014 VPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSV----- 3068

Query: 146  TTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAV 202
                     V +G  +SL+C++   PP    WYK      E   V  L+    L  K A 
Sbjct: 3069 -------VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE 3121

Query: 203  IADSGSYFCTAKGQVGSE 220
            ++D+G Y C A    G +
Sbjct: 3122 VSDTGQYVCRAINVAGRD 3139



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 41/160 (25%), Positives = 60/160 (37%), Gaps = 19/160 (11%)

Query: 88   VSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTT 147
            +  +V    SLQ++ ++  D  HYTC           V     T     KL+V  P    
Sbjct: 4123 IRQRVLSSGSLQIAFVQPGDAGHYTCMAA-------NVAGSSSTST---KLTVHVPPRIR 4172

Query: 148  GSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQT---NNQEPIKVATLSTLLFKPAVIA 204
             +   +TV +  +  L C A G P  +  W K      N            L+ +  V+ 
Sbjct: 4173 STEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAEPYGELILENVVLE 4232

Query: 205  DSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAP 244
            DSG Y C A    G + H+      V  +  +L T TE P
Sbjct: 4233 DSGFYTCVANNAAGEDTHT------VSLTVHVLPTFTELP 4266



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 38/131 (29%), Positives = 58/131 (44%), Gaps = 15/131 (11%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY 151
            V  D SL +  +++ D   YTC  +      N     K T + V  L    PT+  G   
Sbjct: 939  VRSDGSLHIERVQLQDGGEYTCVASNVAGTNN-----KTTSVVVHVL----PTIQHGQQI 989

Query: 152  GFTVPQGMRISLQCQARGSPPISYIWYKQ----QTNNQEPIKVATLSTLLFKPAVIADSG 207
              T+ +G+ ++L C+A G+P  S IW K+     T++ +    A  S  +  P    +SG
Sbjct: 990  LSTI-EGIPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG-EESG 1047

Query: 208  SYFCTAKGQVG 218
             Y CTA    G
Sbjct: 1048 EYVCTATNTAG 1058



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 32/150 (21%), Positives = 63/150 (42%), Gaps = 14/150 (9%)

Query: 95  DVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFT 154
           ++SL+L +++ +D   Y C V+ +       V           L+V +P   T      +
Sbjct: 573 NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVF----------LTVQEPPKVTVMPKNQS 622

Query: 155 VPQGMRISLQCQARGSPPISYIWYKQQTN--NQEPIKVATLSTLLFKPAVIADSGSYFCT 212
              G  +S+ C A G P     W             ++ +  TL  K A   D+G Y C 
Sbjct: 623 FTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGTLFIKNAAPKDAGIYGCL 682

Query: 213 AKGQVGSEQHSDIVKFVVKDSSKLLKTKTE 242
           A    G+++ +  ++++  ++ KL+  ++E
Sbjct: 683 ASNSAGTDKQNSTLRYI--EAPKLMVVQSE 710



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/100 (31%), Positives = 41/100 (41%), Gaps = 11/100 (11%)

Query: 143  PTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS-------T 195
            P+V        TV     ISL C+  G PP    W K    N++PIK+ T +       T
Sbjct: 2964 PSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLK----NEQPIKLNTNTLIVPGGRT 3019

Query: 196  LLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSK 235
            L    A ++D G Y C A  Q G  +    +   V  S K
Sbjct: 3020 LQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIK 3059



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 33/138 (23%), Positives = 59/138 (42%), Gaps = 14/138 (10%)

Query: 86   LHVSHKVP--GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKP 143
            + +SH++   G+ SL +     +D   YTC  T +           + E R   L++  P
Sbjct: 4390 IEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAG---------VVE-RSMSLTLQSP 4439

Query: 144  TVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ--QTNNQEPIKVATLSTLLFKPA 201
             + T       +  G +I L CQA G P  +  W +Q    +  + + V + ++L    A
Sbjct: 4440 PIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSLYIADA 4499

Query: 202  VIADSGSYFCTAKGQVGS 219
               D+  + C A+  +GS
Sbjct: 4500 QKEDTSEFECVARNLMGS 4517



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 17/140 (12%)

Query: 84   GRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKP 143
            GR+ +   + G   LQ+S  E  D + Y+C  +        V      E  +Q     +P
Sbjct: 2243 GRVRI---LSGGRQLQISIAEKSDAALYSCVAS-------NVAGTAKKEYNLQVYI--RP 2290

Query: 144  TVTTGSGYG--FTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLF 198
            T+T    +     V +G  ISL+C+ +G PP +  W K      +   V  L     L  
Sbjct: 2291 TITNSGSHPTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQL 2350

Query: 199  KPAVIADSGSYFCTAKGQVG 218
            K   ++D+G Y C A    G
Sbjct: 2351 KNIHVSDTGRYVCVAVNVAG 2370



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 48/187 (25%), Positives = 71/187 (37%), Gaps = 32/187 (17%)

Query: 94   GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK---LSVSKPTVTTGSG 150
            G   LQ++  +  D  +YTC  +               E + QK   LS+  P    G+ 
Sbjct: 3205 GGSKLQIARSQHSDSGNYTCIASNM-------------EGKAQKYYFLSIQVPPSVAGAE 3251

Query: 151  Y--GFTVPQGMRISLQCQARGSPPISYIWYKQ----QTNNQEPIKV-ATLSTLLFKPAVI 203
                 +V  G  + L C A G P     W K      +   E I+V A  STL    A+ 
Sbjct: 3252 IPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALT 3311

Query: 204  ADSGSYFCTAKGQVGSEQHSDIVKFVV-------KDSSKLLKTKTEAPTTMTYPLKATST 256
            +D+G Y C A    G E     +   V       KD ++ L T  +  T++    +AT T
Sbjct: 3312 SDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVD--TSINIECRATGT 3369

Query: 257  VKQSWDW 263
                 +W
Sbjct: 3370 PPPQINW 3376



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/145 (25%), Positives = 60/145 (41%), Gaps = 11/145 (7%)

Query: 94   GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGF 153
            G   L++ST +++D   YTC  +  +P G+    DK   +RV    V      T      
Sbjct: 3580 GGEVLRISTAQVEDTGRYTCLAS--SPAGDD---DKEYLVRVH---VPPNIAGTDEPRDI 3631

Query: 154  TVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYF 210
            TV +  +++L+C++   PP    W +     Q   +V  LS    L    A + D+ +Y 
Sbjct: 3632 TVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYT 3691

Query: 211  CTAKGQVGSEQHSDIVKFVVKDSSK 235
            C A    G      I+   V  + K
Sbjct: 3692 CVASNIAGKTTREFILTVNVPPNIK 3716



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 46/208 (22%), Positives = 74/208 (35%), Gaps = 40/208 (19%)

Query: 21  PILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQA 80
           P + +PE   G +     +PC+ D L  +T   V+  V  G D    +L++S+       
Sbjct: 431 PKVTMPEKTPGYYLQPGQIPCSVDSLLPFTLSFVRNGVTLGVDQ---YLKESA------- 480

Query: 81  KYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK-LS 139
                          V+L ++ + + D   Y C        G           R Q    
Sbjct: 481 --------------SVNLDIAKVTLSDEGFYECIAVSSAGTG-----------RAQTFFD 515

Query: 140 VSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQ--EPIKVATLS--T 195
           VS+P          TV  G R  L C    +   +  W +   + +  EP ++ TL+  +
Sbjct: 516 VSEPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLS 575

Query: 196 LLFKPAVIADSGSYFCTAKGQVGSEQHS 223
           L  K     D+G Y C    + GS   S
Sbjct: 576 LELKSVKFNDAGEYHCMVSSEGGSSAAS 603



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 41/190 (21%), Positives = 73/190 (38%), Gaps = 18/190 (9%)

Query: 90   HKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGS 149
            H + G   LQ++ +++     YTC  +  +P G+   + +   L V          + G+
Sbjct: 2527 HIISGGRFLQITNVQVPHTGRYTCLAS--SPAGH---KSRSFSLNVFVSPTIAGVGSDGN 2581

Query: 150  GYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL---STLLFKPAVIADS 206
                TV      SL C+A   PP +  W+K  T  +    +  L    TL    A   ++
Sbjct: 2582 PEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNA 2641

Query: 207  GSYFCTAKGQVGSE-QHSDIVKFVVKDSSK---------LLKTKTEAPTTMTYPLKATST 256
            G Y C A  + G   +H ++  ++    +K           + K +   T+T   +A + 
Sbjct: 2642 GRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAI 2701

Query: 257  VKQSWDWTTD 266
               S  W  D
Sbjct: 2702 PSASLSWYKD 2711



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 35/140 (25%), Positives = 60/140 (42%), Gaps = 7/140 (5%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITEL--RVQKLSVSKPTVTTG-SGYGF 153
            +LQ+   ++ D   YTC V       +++  D   ++    QKL      + TG +G   
Sbjct: 2729 TLQIKEAQISDTGRYTC-VASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAK 2787

Query: 154  TVPQGMRISLQCQARGSPPISYIWYKQ---QTNNQEPIKVATLSTLLFKPAVIADSGSYF 210
             V     ISL C+   +PP +  WYK     T++ + + +     L    A + D+G Y 
Sbjct: 2788 DVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYT 2847

Query: 211  CTAKGQVGSEQHSDIVKFVV 230
            C A  + G +     V+ +V
Sbjct: 2848 CVAVNEAGEDSLQYDVRVLV 2867



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 15/129 (11%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSG--YGFTV 155
            LQ++   ++D   YTC  T    +  Q ++          L V +P     +G     TV
Sbjct: 1883 LQIAKTLLEDAGRYTCVATNAAGETQQHIQ----------LHVHEPPSLEDAGKMLNETV 1932

Query: 156  PQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYFCT 212
                 + L+C+A G+P     WYK          +  L+    +  + A I+D+G Y C 
Sbjct: 1933 LVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCV 1992

Query: 213  AKGQVGSEQ 221
            A    G+ +
Sbjct: 1993 AINSAGATE 2001



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 31/132 (23%), Positives = 54/132 (40%), Gaps = 13/132 (9%)

Query: 94   GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYG- 152
            G   L++ + +  DR  Y C  T        V  +K  E++ +   +  P +  G     
Sbjct: 1693 GGKKLEIMSAQEIDRGQYICVAT-------SVAGEK--EIKYEVDVLVPPAIEGGDETSY 1743

Query: 153  FTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLS-TLLFKPAVIADSGSY 209
            F V     + L C   GSPP + +W K  Q  + ++  K+      L+   A ++++G Y
Sbjct: 1744 FIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLY 1803

Query: 210  FCTAKGQVGSEQ 221
             C A    G  +
Sbjct: 1804 RCMAANTAGDHK 1815



 Score = 35.4 bits (80), Expect = 0.092
 Identities = 42/178 (23%), Positives = 67/178 (37%), Gaps = 26/178 (14%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK--LSVSKPTVTTG---SGYG 152
            LQL  + + D   Y C            V   +  +  +K  LSV  P    G   S   
Sbjct: 2348 LQLKNIHVSDTGRYVC------------VAVNVAGMTDKKYDLSVHAPPSIIGNHRSPEN 2395

Query: 153  FTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSY 209
             +V +   +SL C+A G P  S  W+K          V  LS    L      + D+G Y
Sbjct: 2396 ISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQY 2455

Query: 210  FCTAKGQVGSEQH----SDIV--KFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
             C  +   G E+     S +V    V +++ + +K K +   T+T  +      + +W
Sbjct: 2456 TCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITW 2513



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 41/166 (24%), Positives = 64/166 (38%), Gaps = 26/166 (15%)

Query: 84   GRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKP 143
            G  HVS+    D +L +      D   YTC  T        +     TE+    L V +P
Sbjct: 1215 GEHHVSNP---DGTLSIDQATPSDAGIYTCVAT-------NIAGTDETEIT---LHVQEP 1261

Query: 144  TVTTG--SGYGFTVPQ---GMRISLQCQARGSPPISYIWY---KQQTNNQEPIKVATLST 195
                     Y  T  +     RI   C A+G+P  +  W    ++ T  +  I +    T
Sbjct: 1262 PTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGT 1321

Query: 196  LLFKPAVIA-DSGSYFCTAKGQVGSEQHSDIVKF----VVKDSSKL 236
            LL   +V   D+G Y C A  + G+ +    +K     V+KD  ++
Sbjct: 1322 LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQV 1367



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 5/66 (7%)

Query: 161  ISLQCQARGSPPISYIWYK--QQTNNQEPIKVATL---STLLFKPAVIADSGSYFCTAKG 215
            ++L C A G PP +  W K  ++  N + ++V  L   S L    +  +DSG+Y C A  
Sbjct: 3169 VTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASN 3228

Query: 216  QVGSEQ 221
              G  Q
Sbjct: 3229 MEGKAQ 3234



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 35/172 (20%), Positives = 62/172 (36%), Gaps = 21/172 (12%)

Query: 87   HVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVT 146
            H  + +  +  L + +  + D   Y C  T              T+ R   L V  P   
Sbjct: 3757 HARYSILENGFLHIQSAHVTDTGRYLCMATNAAG----------TDRRRIDLQVHVPPSI 3806

Query: 147  TGSGYGFTVPQGMRISLQCQARGSPPISYIWYK-----QQTNNQEPIKVATLSTLLFKPA 201
                   TV   ++ +L C+A G P  S  W K         NQ   ++ +  +L+    
Sbjct: 3807 APGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISP 3866

Query: 202  VIADSGSYFCTAKGQVGSEQHS-----DIVKFVVKDSSKLLKTKTEAPTTMT 248
             + D+ +Y CT     G ++ +      +   +  + +  L TK  AP  +T
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTK-HAPAVIT 3917



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 35/124 (28%), Positives = 51/124 (41%), Gaps = 15/124 (12%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L L  + ++D   YTC       +    V      L V  L    PT T   G   ++ +
Sbjct: 4224 LILENVVLEDSGFYTCVANNAAGEDTHTV-----SLTVHVL----PTFTELPG-DVSLNK 4273

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL---STLLFKPAVIADSGSYFCTAK 214
            G ++ L C+A G P     W     NN  P    ++   S L+ +     DSG+Y CTA+
Sbjct: 4274 GEQLRLSCKATGIPLPKLTW--TFNNNIIPAHFDSVNGHSELVIERVSKEDSGTYVCTAE 4331

Query: 215  GQVG 218
              VG
Sbjct: 4332 NSVG 4335



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 32/129 (24%), Positives = 51/129 (39%), Gaps = 11/129 (8%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L L     +D+  Y C V+     G Q    K+T       S+    VTT      +V  
Sbjct: 1510 LHLKNARRNDKGRYQCTVS--NAAGKQAKDIKLTIYIPP--SIKGGNVTTD----ISVLI 1561

Query: 158  GMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVATLSTLLFKPAVIADSGSYFCTAK 214
               I L+C+ RG P  +  WYK      ++ + + +     L    A ++DS +Y C   
Sbjct: 1562 NSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTCHVA 1621

Query: 215  GQVGSEQHS 223
               G+ + S
Sbjct: 1622 NVAGTAEKS 1630



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 35/141 (24%), Positives = 55/141 (39%), Gaps = 8/141 (5%)

Query: 143  PTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK--QQTNN-QEPIKVATLSTLL-F 198
            PT+ +       V +   ++LQC A G P  S  W K  Q  N  Q  +K+ +   +L  
Sbjct: 1826 PTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQI 1885

Query: 199  KPAVIADSGSYFCTAKGQVG-SEQHSDIVKF---VVKDSSKLLKTKTEAPTTMTYPLKAT 254
               ++ D+G Y C A    G ++QH  +       ++D+ K+L         +    KA 
Sbjct: 1886 AKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECKAA 1945

Query: 255  STVKQSWDWTTDMDGYLGETS 275
                    W  D     G TS
Sbjct: 1946 GNPVPVITWYKDNRLLSGSTS 1966



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 34/141 (24%), Positives = 55/141 (39%), Gaps = 41/141 (29%)

Query: 98   LQLSTLEMDDRSHYTCEVT--------------WQTPDGNQVVRDKITELRVQKLSVSKP 143
            L++   ++ D   YTCE T              W  P  N    D++T+L          
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPP--NIGGSDELTQL---------- 2206

Query: 144  TVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ----QTNNQEPIKVATLS-TLLF 198
                      TV +G  ISL C++ G PP + IW K+     T++   +++ +    L  
Sbjct: 2207 ----------TVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQI 2256

Query: 199  KPAVIADSGSYFCTAKGQVGS 219
              A  +D+  Y C A    G+
Sbjct: 2257 SIAEKSDAALYSCVASNVAGT 2277



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 147  TGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ---QTNNQEPIKVATLSTLL-FKPAV 202
            +GS     V     + L+C+ARG P  S  W K     ++    ++V +   +L    A 
Sbjct: 2015 SGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQ 2074

Query: 203  IADSGSYFCTAKGQVGSEQ 221
            I+D+G Y C A    G +Q
Sbjct: 2075 ISDTGRYTCVAVNAAGEKQ 2093



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 35/136 (25%), Positives = 49/136 (36%), Gaps = 17/136 (12%)

Query: 94   GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELR-VQKLSVSKPTVTTGSGY- 151
            G   L+L    M+D   YTC           VVR+   E R +  LSV  P    G    
Sbjct: 2438 GGRMLRLMQTTMEDAGQYTC-----------VVRNAAGEERKIFGLSVLVPPHIVGENTL 2486

Query: 152  -GFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSG 207
                V +   ++L C+  G+P     W+K     QE      +S    L      +  +G
Sbjct: 2487 EDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGRFLQITNVQVPHTG 2546

Query: 208  SYFCTAKGQVGSEQHS 223
             Y C A    G +  S
Sbjct: 2547 RYTCLASSPAGHKSRS 2562



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 47/207 (22%), Positives = 76/207 (36%), Gaps = 25/207 (12%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            S++++     D   Y C  T    +  Q V          KL+V  P           V 
Sbjct: 1134 SMKITETRTSDSGMYLCVATNIAGNVTQAV----------KLNVHVPPKIQRGPKHLKVQ 1183

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTN---NQEPIKVATLSTLLFKPAVIADSGSYFCTA 213
             G R+ + C A+G+P     W K  +    + E        TL    A  +D+G Y C A
Sbjct: 1184 VGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVA 1243

Query: 214  KGQVGSEQHSDIVKFV-----VKDSSKLLKTKTE---APTTMTYPLKATSTVKQSWDWTT 265
                G+++ ++I   V     V+D      T  +   A   + +P  A  T K +  W  
Sbjct: 1244 TNIAGTDE-TEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLH 1302

Query: 266  DMDGYLGETSAGPGKSLPVFAIILIIS 292
            +     G     PG S+     +L+I+
Sbjct: 1303 NGRELTGRE---PGISILEDGTLLVIA 1326



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 24/96 (25%), Positives = 37/96 (38%), Gaps = 7/96 (7%)

Query: 138 LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNN--QEPIKVATLST 195
           L V  P V        ++  G  ++L C  +G P  +  W +         P  V+++S 
Sbjct: 787 LDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQ 846

Query: 196 LLFKPAVI-----ADSGSYFCTAKGQVGSEQHSDIV 226
           L      I     +D G+Y C A+ Q G  Q    V
Sbjct: 847 LRTGALFILNLWASDKGTYICEAENQFGKIQSETTV 882



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 27/104 (25%), Positives = 40/104 (38%), Gaps = 3/104 (2%)

Query: 154  TVPQGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLL-FKPAVIADSGSYF 210
            TV +G   S+ C   G+P  S  W +  Q       + V+T   +L    A   DSG Y 
Sbjct: 3446 TVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYT 3505

Query: 211  CTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPLKAT 254
            C A  + G      I+K +        +   E    +  PL+ T
Sbjct: 3506 CIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVIVNNPLELT 3549



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/62 (33%), Positives = 29/62 (46%), Gaps = 3/62 (4%)

Query: 161  ISLQCQARGSPPISYIWYKQQTN-NQEPIKVATLST--LLFKPAVIADSGSYFCTAKGQV 217
            I L C+A G+P     W K+  N N      A L +  L    AV  D+G+Y C A+   
Sbjct: 4005 ILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPA 4064

Query: 218  GS 219
            G+
Sbjct: 4065 GT 4066



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 3/63 (4%)

Query: 162  SLQCQARGSPPISYIWYKQQTNNQEPIKVATLST---LLFKPAVIADSGSYFCTAKGQVG 218
            +L C+  G+P    +WYK      E   + T++    L    A   D+G Y C A    G
Sbjct: 1379 NLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAG 1438

Query: 219  SEQ 221
            + Q
Sbjct: 1439 TSQ 1441



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 27/127 (21%), Positives = 46/127 (36%), Gaps = 13/127 (10%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L L++ ++ D   YTC       +  + +           L V  P    G     +V  
Sbjct: 2068 LALTSAQISDTGRYTCVAVNAAGEKQRDI----------DLRVYVPPNIMGEEQNVSVLI 2117

Query: 158  GMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVA-TLSTLLFKPAVIADSGSYFCTAK 214
               + L CQ+   PP +  W K       +  + ++   S L  + A + D+G Y C A 
Sbjct: 2118 SQAVELLCQSDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTGRYTCEAT 2177

Query: 215  GQVGSEQ 221
               G  +
Sbjct: 2178 NVAGKTE 2184



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 33/135 (24%), Positives = 47/135 (34%), Gaps = 17/135 (12%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY 151
            +PG   LQ+   +++D   YTC         N+   D +       + V  P +  G+  
Sbjct: 2827 LPGGRVLQIPRAKVEDAGRYTCVAV------NEAGEDSLQ----YDVRVLVPPIIKGANS 2876

Query: 152  GF----TVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST---LLFKPAVIA 204
                  TV       ++C + GSP     W K      E      LS    L      I 
Sbjct: 2877 DLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQIT 2936

Query: 205  DSGSYFCTAKGQVGS 219
            D G Y C A+   GS
Sbjct: 2937 DIGRYVCVAENTAGS 2951



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 39/158 (24%), Positives = 60/158 (37%), Gaps = 24/158 (15%)

Query: 96   VSLQLSTLEM-----DDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSG 150
            VS   STL +      D   YTC  T   P G +   D+I  L V      +        
Sbjct: 3297 VSANGSTLNIYGALTSDTGKYTCVAT--NPAGEE---DRIFNLNVYVTPTIRGNKDEAEK 3351

Query: 151  YGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI------- 203
                V     I+++C+A G+PP    W K    N  P+ +++   LL    VI       
Sbjct: 3352 LMTLVDTS--INIECRATGTPPPQINWLK----NGLPLPLSSHIRLLAAGQVIRIVRAQV 3405

Query: 204  ADSGSYFCTAKGQVG-SEQHSDIVKFVVKDSSKLLKTK 240
            +D   Y C A  + G   +H ++  F   +    + T+
Sbjct: 3406 SDVAVYTCVASNRAGVDNKHYNLQVFAPPNMDNSMGTE 3443


>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
          Length = 1215

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 95  DVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFT 154
           D+SL++S +   D   Y C  +    + N V R  +  L  +   VS  T    S   F+
Sbjct: 452 DLSLEISGIIPTDGGRYQCVAS----NANGVTRASVWLLVREAPQVSIHT----SSQHFS 503

Query: 155 VPQGMRISLQCQARGSPPISYIWYKQQTNNQEP--IKVATLSTLLFKPAVIADSGSYFCT 212
             QG+ + + C A G P     W ++    QE   I V    TL+ +     D+G+Y C 
Sbjct: 504 --QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQ 561

Query: 213 AKGQVGSEQHS 223
           A  +VG++Q +
Sbjct: 562 ATNEVGTDQET 572



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 39/132 (29%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 90  HKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGS 149
           H +  D SL L     +    Y+C  T     G+Q    +  EL VQ      PT T   
Sbjct: 815 HSIRADGSLHLDRALQEHAGRYSCVAT--NTAGSQ---HRDVELVVQVPPRIHPTATH-- 867

Query: 150 GYGFTVPQGMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVATLSTLLFKPAVIADS 206
                  +G+  SL C A G P  +  W K+    T+      V+   TLL       D+
Sbjct: 868 ---HITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDA 924

Query: 207 GSYFCTAKGQVG 218
           G+Y CTA   VG
Sbjct: 925 GAYVCTATNTVG 936



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 35/146 (23%), Positives = 53/146 (36%), Gaps = 26/146 (17%)

Query: 90   HKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGS 149
            + V  + +L ++     D   Y C  T      +Q +R  +          +KP +    
Sbjct: 906  YNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVN---------TKPRIHMNG 956

Query: 150  GYGFTVP------QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVAT-------LSTL 196
                 VP       G  ++L C+A+GSPP    W    T +  P+   T         +L
Sbjct: 957  SRNANVPLQVTAKAGEEVTLDCEAKGSPPPLVTW----TKDSRPVPPITNRYGLLPSGSL 1012

Query: 197  LFKPAVIADSGSYFCTAKGQVGSEQH 222
                  + DSG Y CTA    GS  H
Sbjct: 1013 RLAQVQVGDSGHYECTASNPAGSASH 1038



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 20/174 (11%)

Query: 78  QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK 137
           Q  +   R+HV        +L +  +  +D  +Y+C+ T      N+V  D+ T      
Sbjct: 529 QALQEDSRIHVD----AQGTLIIQGVAPEDAGNYSCQAT------NEVGTDQETVT---- 574

Query: 138 LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL 197
           L  + P   +       V  G    L C+A G PP   IWY+         + ++   L 
Sbjct: 575 LYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKLR 634

Query: 198 FKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPL 251
              A   D+G+Y C A  ++G    S  ++  V  + +L    TE P  +T  L
Sbjct: 635 IPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQL----TELPRDVTVEL 682



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 33/154 (21%), Positives = 52/154 (33%), Gaps = 27/154 (17%)

Query: 82  YQGRLHVSHKVPGDVS--LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLS 139
           Y+G L +     G  S  L++   +  D   YTC    +  D +  ++          L+
Sbjct: 615 YRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQ----------LA 664

Query: 140 VSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPI----------- 188
           V      T      TV  G    L C+A G PP +  W   +  + +P+           
Sbjct: 665 VGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTW---RRGDGQPLGLRLGAGRGSR 721

Query: 189 -KVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQ 221
            +      L F+     D   Y C A+   G  Q
Sbjct: 722 SRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQ 755


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 95  DVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFT 154
           D+SL++S +   D   Y C  +    + N V R  +  L  +   VS  T    S   F+
Sbjct: 569 DLSLEISGIIPTDGGRYQCVAS----NANGVTRASVWLLVREAPQVSIHT----SSQHFS 620

Query: 155 VPQGMRISLQCQARGSPPISYIWYKQQTNNQEP--IKVATLSTLLFKPAVIADSGSYFCT 212
             QG+ + + C A G P     W ++    QE   I V    TL+ +     D+G+Y C 
Sbjct: 621 --QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQ 678

Query: 213 AKGQVGSEQHS 223
           A  +VG++Q +
Sbjct: 679 ATNEVGTDQET 689



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 36/132 (27%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY 151
            +PG   LQ+   + +D   YTC VT +   G  V    +  L    +S   P    G   
Sbjct: 2591 LPGTHGLQILNAQKEDAGQYTCVVTNEL--GEAVKNYHVEVLIPPSISKDDPLGEVGVKE 2648

Query: 152  GFTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLL-FKPAVIADSGS 208
              T      ++L+C++   PP +  WYK  Q       ++V     LL  +P  ++DSG 
Sbjct: 2649 VKT-KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 2707

Query: 209  YFCTAKGQVGSE 220
            Y C A    G +
Sbjct: 2708 YLCVATNVAGED 2719



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 61/248 (24%), Positives = 91/248 (36%), Gaps = 33/248 (13%)

Query: 23   LEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQAKY 82
            + VP  +T P       P    P+   T V +         P  ++L+D  G+ +  A  
Sbjct: 1973 VNVPPRITLP-------PSLPGPVLVNTPVRLTCNATGAPSPTLMWLKD--GNPVSPAGT 2023

Query: 83   QGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSK 142
             G L V    PG   L L++    D   Y+C       +  Q V           L V  
Sbjct: 2024 PG-LQV---FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDV----------VLQVHM 2069

Query: 143  PTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST----LLF 198
            P    G     +V     ++L+CQ+   PP    W+K      EP     LS     L  
Sbjct: 2070 PPSILGEELNVSVVANESVALECQSHAMPPPVLSWWK-DGRPLEPRPGVHLSADKALLQV 2128

Query: 199  KPAVIADSGSYFCTAKGQVG-SEQHSDIVKFVVK----DSSKLLKTKTEAPTTMTYPLKA 253
              A + D+G Y C A  Q G SE+H ++  +V        S  L  +   PT+++   + 
Sbjct: 2129 DRADVWDAGHYTCEALNQAGHSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRG 2188

Query: 254  TSTVKQSW 261
                K SW
Sbjct: 2189 VPFPKISW 2196



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 39/132 (29%), Positives = 52/132 (39%), Gaps = 13/132 (9%)

Query: 90   HKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGS 149
            H +  D SL L     +    Y+C  T     G+Q    +  EL VQ      PT T   
Sbjct: 932  HSIRADGSLHLDRALQEHAGRYSCVAT--NTAGSQ---HRDVELVVQVPPRIHPTATH-- 984

Query: 150  GYGFTVPQGMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVATLSTLLFKPAVIADS 206
                   +G+  SL C A G P  +  W K+    T+      V+   TLL       D+
Sbjct: 985  ---HITNEGVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQDA 1041

Query: 207  GSYFCTAKGQVG 218
            G+Y CTA   VG
Sbjct: 1042 GAYVCTATNTVG 1053



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 44/179 (24%), Positives = 68/179 (37%), Gaps = 26/179 (14%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELR---VQKLSVSKPTVTTGSGYGFT 154
            LQLS L+      YTC           V  +   E R   V  + V+    ++G      
Sbjct: 3180 LQLSRLQPAQAGTYTC-----------VAENTQAEARKDFVVAVLVAPRIRSSGVAREHH 3228

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQT---NNQEPIKVATL--STLLFKPAVIADSGSY 209
            V +G  + L C+A G PP    W K  +    +  P     L   +L+ K    +D+G+Y
Sbjct: 3229 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 3288

Query: 210  FCTAKGQVGSEQHSDIVKFVV-------KDSSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
             C A    G +     V  +V        D S  L ++     TM  P++ +  +  SW
Sbjct: 3289 TCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSW 3347



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 13/127 (10%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQ+  +++ D   YTC  T    +  + V  K+         +  P +  G      V +
Sbjct: 1850 LQIEKVDLRDEGIYTCAATNLAGESKREVALKV---------LVPPNIEPGP-VNKAVLE 1899

Query: 158  GMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLL-FKPAVIADSGSYFCTAK 214
               ++L+C A G PP    W+K  Q  ++   + V+    +L  + A ++D+GSY C A 
Sbjct: 1900 NASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVAS 1959

Query: 215  GQVGSEQ 221
               GS +
Sbjct: 1960 NVAGSTE 1966



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 12/127 (9%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQ+ST E+ D + Y C    Q         +K+  LRVQ      P +        T   
Sbjct: 2901 LQVSTAEVADAASYMCVAENQAGSA-----EKLFTLRVQV----PPRIAGLDLEQVTAIL 2951

Query: 158  GMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVATLSTLLFKPAVIADSGSYFCTAK 214
               +SL C     P     WYK     +  +E   +    TL    A ++DSG Y C A 
Sbjct: 2952 NSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEAL 3011

Query: 215  GQVGSEQ 221
               G +Q
Sbjct: 3012 NAAGRDQ 3018



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 16/128 (12%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVS-KPTVTTGS-GYGFT 154
            SL L  L   D   YTC      P G         + R+  ++V   PT+  G+ G G  
Sbjct: 3274 SLVLKGLRASDAGAYTCVA--HNPAGE--------DARLHTVNVLVPPTIKQGADGSGTL 3323

Query: 155  VPQ-GMRISLQCQARGSPPISYIWYKQQTN---NQEPIKVATLSTLLFKPAVIADSGSYF 210
            V + G  +++ C  RGSPPI   W K       +Q  +   +  TL      +AD+G + 
Sbjct: 3324 VSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFT 3383

Query: 211  CTAKGQVG 218
            C A    G
Sbjct: 3384 CVAASPAG 3391



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 17/131 (12%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGF---- 153
            LQ+  +  ++   Y+C+ +      N+V  D +      +L V  P V  G         
Sbjct: 2806 LQIPLVRAENAGRYSCKAS------NEVGEDWLH----YELLVLTPPVILGDTEELVEEV 2855

Query: 154  TVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYF 210
            TV     +SLQC A G+P  +  W +         ++  L     L    A +AD+ SY 
Sbjct: 2856 TVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYM 2915

Query: 211  CTAKGQVGSEQ 221
            C A+ Q GS +
Sbjct: 2916 CVAENQAGSAE 2926



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +L++S +++ D   +TC     +P G   V D+   L+VQ   V +P           V 
Sbjct: 3368 TLRISKVQLADAGIFTCVAA--SPAG---VADRNFTLQVQVPPVLEPVEFQND---VVVV 3419

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYFCTA 213
            +G  + L C+ARG P     W K    + EP+   +L    +L  +     DSG+Y C A
Sbjct: 3420 RGSLVELPCEARGVPLPLVSWMK----DGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVA 3475

Query: 214  KGQVG 218
              + G
Sbjct: 3476 VSEAG 3480



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 46/200 (23%), Positives = 73/200 (36%), Gaps = 21/200 (10%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQL  L   D   Y+C  T +   G+  V  ++    V  +    P V         +P 
Sbjct: 3637 LQLQALSTADSGDYSC--TARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLP- 3693

Query: 158  GMRISLQCQARGSPPISYIWYKQQT--NNQEP-IKVATLSTLLFKPAVIADSGSYFCTAK 214
                   CQA G P     W K +   + + P  ++    +L  +P +  D+G Y C A 
Sbjct: 3694 -------CQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLAS 3746

Query: 215  GQVGSEQHSDIVKF-----VVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTDMDG 269
               GS++    ++      +    S L  T   A T    P +A+ + K    W  D   
Sbjct: 3747 NSAGSDRQGRDLRVLEPPAIAPSPSNLTLT---AHTPALLPCEASGSPKPLVVWWKDGQK 3803

Query: 270  YLGETSAGPGKSLPVFAIIL 289
                   G  + LP  A++L
Sbjct: 3804 LDFRLQQGAYRLLPSNALLL 3823



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 13/135 (9%)

Query: 87   HVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVT 146
            H+ H++    SL +   E DD   Y C       +    V  K+  L +Q   V +    
Sbjct: 4263 HLRHQLQNG-SLTIHRTERDDAGRYQC-----LAENEMGVAKKVVILVLQSAPVFQV--- 4313

Query: 147  TGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--STLLFKPAVIA 204
                   TV  G  ++L+CQA G P  +  W +     +   ++ TL   +L  +     
Sbjct: 4314 --EPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETG 4371

Query: 205  DSGSYFCTAKGQVGS 219
            D+G+Y C A   +GS
Sbjct: 4372 DAGTYDCVAHNLLGS 4386



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 42/174 (24%), Positives = 69/174 (39%), Gaps = 20/174 (11%)

Query: 78  QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK 137
           Q  +   R+HV        +L +  +  +D  +Y+C+ T      N+V  D+ T      
Sbjct: 646 QALQEDSRIHVD----AQGTLIIQGVAPEDAGNYSCQAT------NEVGTDQETVT---- 691

Query: 138 LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL 197
           L  + P   +       V  G    L C+A G PP   IWY+         + ++   L 
Sbjct: 692 LYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKLR 751

Query: 198 FKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTYPL 251
              A   D+G+Y C A  ++G    S  ++  V  + +L    TE P  +T  L
Sbjct: 752 IPAAQERDAGTYTCRAVNELGDA--SAEIQLAVGHAPQL----TELPRDVTVEL 799



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 4/66 (6%)

Query: 158  GMRISLQCQARGSPPISYIWYK----QQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTA 213
            G   SL C ARG+P     W K    +  + Q  + V    +L       ADSG Y C A
Sbjct: 1221 GENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQA 1280

Query: 214  KGQVGS 219
              +VGS
Sbjct: 1281 TNEVGS 1286



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 39/125 (31%), Positives = 52/125 (41%), Gaps = 11/125 (8%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L +  LE  D   YTC         N V R +    RV    +  P  TT  G   ++  
Sbjct: 4093 LLVKNLEGQDAGTYTCTAE------NAVGRAR---RRVHLTILVLPVFTTLPG-DRSLRL 4142

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIA-DSGSYFCTAKGQ 216
            G R+ L+C ARGSP     W        E +      + L + AV   DSG+Y C A+ +
Sbjct: 4143 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 4202

Query: 217  VGSEQ 221
            VG  Q
Sbjct: 4203 VGRTQ 4207



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 137  KLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQE-PIKVATL 193
            +L V  P V        +  +G    L C+ARGSP  +  W K  Q  +  E    +   
Sbjct: 4031 RLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPS 4090

Query: 194  STLLFKPAVIADSGSYFCTAKGQVG 218
              LL K     D+G+Y CTA+  VG
Sbjct: 4091 GELLVKNLEGQDAGTYTCTAENAVG 4115



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 39/161 (24%), Positives = 62/161 (38%), Gaps = 25/161 (15%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKP----TVTT 147
            +PG  +LQL    + D   YTCE        N   RD+    ++ +LSV  P        
Sbjct: 2987 LPGTHTLQLGRARLSDSGMYTCEAL------NAAGRDQ----KLVQLSVLVPPAFRQAPR 3036

Query: 148  GSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL-------FKP 200
            G      V  G +  L C+    P  +  WYK    + +P+ +A  +  L        + 
Sbjct: 3037 GPQDAVLVRVGDKAVLSCETDALPEPTVTWYK----DGQPLVLAQRTQALRGGQRLEIQE 3092

Query: 201  AVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKT 241
            A ++D G Y C      G    +  +   V  + +  KT+T
Sbjct: 3093 AQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTET 3133



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 36/131 (27%), Positives = 50/131 (38%), Gaps = 16/131 (12%)

Query: 94   GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQV-VRDKITELRVQKLSVSKPTVTTGSGYG 152
            G   LQL   +  D   YTC+ +      N V   +K T L V       PT+    G  
Sbjct: 1554 GGRQLQLGRAQSSDAGVYTCKAS------NAVGAAEKATRLDVYV----PPTIEGAGGRP 1603

Query: 153  FTVPQ--GMRISLQCQARGSPPISYIWYKQ---QTNNQEPIKVATLSTLLFKPAVIADSG 207
            + V    G  ++L+C ARG P  +  W+ +      + E       S L  +    A SG
Sbjct: 1604 YVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSG 1663

Query: 208  SYFCTAKGQVG 218
             Y C A    G
Sbjct: 1664 LYSCVASSPAG 1674



 Score = 35.8 bits (81), Expect = 0.070
 Identities = 35/131 (26%), Positives = 51/131 (38%), Gaps = 22/131 (16%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQ+   ++ D  HYTCE   Q         +K   L V       P       +  TV +
Sbjct: 2126 LQVDRADVWDAGHYTCEALNQAGHS-----EKHYNLNVWVA----PVFPLRESHTLTVRE 2176

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPI--------KVATLSTLLF-KPAVIADSGS 208
            G   SL C+ RG P     W K    + +P+         V+ +  LL+   A +A  G+
Sbjct: 2177 GHPTSLSCECRGVPFPKISWRK----DGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGT 2232

Query: 209  YFCTAKGQVGS 219
            Y C     VG+
Sbjct: 2233 YTCECSNVVGN 2243



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 40/148 (27%), Positives = 61/148 (41%), Gaps = 14/148 (9%)

Query: 78   QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK 137
            +Q    G  H+  +  G V L+++   + D   Y C     +P G Q  RD   +LRV  
Sbjct: 1446 RQPVLPGGPHLQVQEDGQV-LRITGSHVGDEGRYQCVAF--SPAGQQA-RD--FQLRVH- 1498

Query: 138  LSVSKPTVTTGSGYG-FTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--- 193
               + PT+   +  G   V +   + L C+ARG P  +  W+K         KV      
Sbjct: 1499 ---APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGG 1555

Query: 194  STLLFKPAVIADSGSYFCTAKGQVGSEQ 221
              L    A  +D+G Y C A   VG+ +
Sbjct: 1556 RQLQLGRAQSSDAGVYTCKASNAVGAAE 1583



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 39/176 (22%), Positives = 63/176 (35%), Gaps = 29/176 (16%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            SL+L+ +++ D  HY C  T   P G+   R          L V  P           V 
Sbjct: 1083 SLRLAQVQVGDSGHYEC--TASNPAGSASHR--------YVLGVQVPPQVQPGPRVLKVL 1132

Query: 157  QGMRISLQCQARGSPPISYIWYK-----QQTNNQEPIKVATLSTLLFKPAVIADSGSYFC 211
             G  + L C A G+P     W K     Q    Q  +  A + T        +D+G Y C
Sbjct: 1133 VGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIRT--------SDAGRYRC 1184

Query: 212  TAKGQVGSEQHSDIVKFV------VKDSSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
             A    G +     ++ +        ++S LL+       ++  P + T   + +W
Sbjct: 1185 EASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTW 1240



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 32/131 (24%), Positives = 49/131 (37%), Gaps = 7/131 (5%)

Query: 161  ISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--STLLFKPAVIADSGSYFCTAKGQVG 218
            + L C+A G P  +  W K+  N    +    L    L    A   D+G+Y C AK   G
Sbjct: 3965 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG 4024

Query: 219  SEQHSD--IVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTD---MDGYLGE 273
            S       +V+      + L    T   +    P KA  + + +  W  D   + G  G+
Sbjct: 4025 SAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGK 4084

Query: 274  TSAGPGKSLPV 284
             +  P   L V
Sbjct: 4085 FTIQPSGELLV 4095



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 34/132 (25%), Positives = 52/132 (39%), Gaps = 21/132 (15%)

Query: 94   GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGF 153
            G  +LQ + +  +D   Y C   W     N+V R +     V  + V +  V  G  + +
Sbjct: 4178 GGSTLQRAAVSREDSGTYVC---WAE---NRVGRTQA----VSFVHVKEAPVLQGEAFSY 4227

Query: 154  TV-PQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL------STLLFKPAVIADS 206
             V P G  I L C  RG P     W K       P++ + L       +L        D+
Sbjct: 4228 LVEPVGGSIQLDCVVRGDPVPDIHWIKDGL----PLRGSHLRHQLQNGSLTIHRTERDDA 4283

Query: 207  GSYFCTAKGQVG 218
            G Y C A+ ++G
Sbjct: 4284 GRYQCLAENEMG 4295



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 31/135 (22%), Positives = 52/135 (38%), Gaps = 28/135 (20%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYG--FT 154
            SLQL  +   D   Y+C    +  +            R  +L+V +P     SG     +
Sbjct: 3457 SLQLEAVGAGDSGTYSCVAVSEAGEAR----------RHFQLTVMEPPHIEDSGQPTELS 3506

Query: 155  VPQGMRISLQCQARGSPPISYIWYK------QQTNNQEPIKVATLSTLLFKPAVIADSGS 208
            +  G  + L C A+G+P  +  W+K      +  NN    +V            + D+G 
Sbjct: 3507 LTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLR----------VRDAGL 3556

Query: 209  YFCTAKGQVGSEQHS 223
            Y C A+   G+ + S
Sbjct: 3557 YTCLAESPAGAIEKS 3571



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 13/113 (11%)

Query: 111  YTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYG-FTVPQGMRISLQCQARG 169
            Y+C  +  +P G  V++  + E++V       P +    G G  T   G  + L CQA G
Sbjct: 1665 YSCVAS--SPAGEAVLQYSV-EVQVP------PQLLVAEGLGQVTTIVGQPLELPCQASG 1715

Query: 170  SPPISYIWYKQQTNNQE--PIKVATLSTLLFKPAVIAD-SGSYFCTAKGQVGS 219
            SP  +  W +     +E   ++VA+  T L    V  D SG + C A  + G+
Sbjct: 1716 SPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGT 1768



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 11/80 (13%)

Query: 161  ISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI-------ADSGSYFCTA 213
            ++L C+A G PP +  W++     +EP+     + LL    ++        DSG Y C A
Sbjct: 2370 LTLLCEAMGIPPPAIRWFR----GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 2425

Query: 214  KGQVGSEQHSDIVKFVVKDS 233
              + G  + +  V+ +V  S
Sbjct: 2426 SNEAGEARRNFSVEVLVPPS 2445



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 29/129 (22%)

Query: 103  LEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGM-RI 161
            L + D   YTC    ++P G     +K   +RVQ    + P +    G  F V     ++
Sbjct: 3549 LRVRDAGLYTCLA--ESPAG---AIEKSFRVRVQ----APPNIVGPRGPRFVVGLAPGQL 3599

Query: 162  SLQCQARGSPPISYIWYK------QQTNNQEP-----IKVATLSTLLFKPAVIADSGSYF 210
             L+C     P     W++      +  + Q P     +++  LST        ADSG Y 
Sbjct: 3600 VLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST--------ADSGDYS 3651

Query: 211  CTAKGQVGS 219
            CTA+   GS
Sbjct: 3652 CTARNAAGS 3660



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 37/145 (25%), Positives = 50/145 (34%), Gaps = 30/145 (20%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            SL L+++   D   Y C+ T      N+V        R  KL V  P      G    V 
Sbjct: 1262 SLFLASVSPADSGDYECQAT------NEVGSTS----RRAKLVVYVPPSIREDGRKANVS 1311

Query: 157  --QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL------------------STL 196
               G  ++L+C A G P    +W K       P+  A                     +L
Sbjct: 1312 GMAGQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSL 1371

Query: 197  LFKPAVIADSGSYFCTAKGQVGSEQ 221
             F      DSG Y C A+ Q G+ Q
Sbjct: 1372 HFPRIQEGDSGLYSCRAENQAGTAQ 1396



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 33/154 (21%), Positives = 52/154 (33%), Gaps = 27/154 (17%)

Query: 82  YQGRLHVSHKVPGDVS--LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLS 139
           Y+G L +     G  S  L++   +  D   YTC    +  D +  ++          L+
Sbjct: 732 YRGGLEMILAPEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQ----------LA 781

Query: 140 VSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPI----------- 188
           V      T      TV  G    L C+A G PP +  W   +  + +P+           
Sbjct: 782 VGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTW---RRGDGQPLGLRLGAGRGSR 838

Query: 189 -KVATLSTLLFKPAVIADSGSYFCTAKGQVGSEQ 221
            +      L F+     D   Y C A+   G  Q
Sbjct: 839 SRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQ 872



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 125  VVRDKITEL-RVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK---Q 180
            VV +++ E  R+ +++V  P         FTV     + L C + G P  +  W K   Q
Sbjct: 3837 VVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 3896

Query: 181  QTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVG 218
                    +V+    L    A+   +G Y C+A+   G
Sbjct: 3897 LGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 3934



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 163  LQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLLFKPAVIAD-SGSYFCTAKGQVGS 219
            L C     PP    WY+  Q  +  + + V     +L  P V A+ +G Y C A  +VG 
Sbjct: 2770 LYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGE 2829

Query: 220  E 220
            +
Sbjct: 2830 D 2830


>gi|239743951 PREDICTED: hypothetical protein XP_002342997 [Homo
           sapiens]
          Length = 790

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 37/131 (28%), Positives = 59/131 (45%), Gaps = 12/131 (9%)

Query: 95  DVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFT 154
           D+SL++S +   D   Y C  +    + N V R  +  L  +   VS  T    S   F+
Sbjct: 568 DLSLEISGIIPTDGGRYQCVAS----NANGVTRASVWLLVREAPQVSIHT----SSQHFS 619

Query: 155 VPQGMRISLQCQARGSPPISYIWYKQQTNNQEP--IKVATLSTLLFKPAVIADSGSYFCT 212
             QG+ + + C A G P     W ++    QE   I V    TL+ +     D+G+Y C 
Sbjct: 620 --QGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAGNYSCQ 677

Query: 213 AKGQVGSEQHS 223
           A  +VG++Q +
Sbjct: 678 ATNEVGTDQET 688



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 34/141 (24%), Positives = 56/141 (39%), Gaps = 14/141 (9%)

Query: 78  QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK 137
           Q  +   R+HV        +L +  +  +D  +Y+C+ T      N+V  D+ T      
Sbjct: 645 QALQEDSRIHVD----AQGTLIIQGVAPEDAGNYSCQAT------NEVGTDQETVT---- 690

Query: 138 LSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL 197
           L  + P   +       V  G    L C+A G PP   IWY+         + ++   L 
Sbjct: 691 LYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGLEMILAPEGSSSGKLR 750

Query: 198 FKPAVIADSGSYFCTAKGQVG 218
              A   D+G+Y C A  ++G
Sbjct: 751 IPAAQERDAGTYTCRAVNELG 771


>gi|21361905 junctional adhesion molecule 3 precursor [Homo sapiens]
          Length = 355

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 43/153 (28%), Positives = 62/153 (40%), Gaps = 22/153 (14%)

Query: 81  KYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSV 140
           K QG L    ++ G  SL++  +   D + Y CEV  +        R +I E+ ++ L+V
Sbjct: 128 KIQGDLAGRAEILGKTSLKIWNVTRRDSALYRCEVVARND------RKEIDEIVIE-LTV 180

Query: 141 SKPTVTTGSGYGFTVPQGMRISLQCQ-ARGSPPISYIWYKQQT-------------NNQE 186
               VT        VP G   +L CQ + G P   Y WY+                N+  
Sbjct: 181 QVKPVTPVCRVPKAVPVGKMATLHCQESEGHPRPHYSWYRNDVPLPTDSRANPRFRNSSF 240

Query: 187 PIKVATLSTLLFKPAVIADSGSYFCTAKGQVGS 219
            +   T  TL+F      DSG Y+C A    GS
Sbjct: 241 HLNSET-GTLVFTAVHKDDSGQYYCIASNDAGS 272


>gi|38490688 immunoglobulin superfamily, member 10 [Homo sapiens]
          Length = 2623

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 47/199 (23%), Positives = 73/199 (36%), Gaps = 32/199 (16%)

Query: 29   VTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQAKYQGRLHV 88
            + G W   + LPCT    +G  Q  V W++  G++   +   +S            +L +
Sbjct: 1852 IVGTWGESLKLPCT---AKGTPQPSVYWVLSDGTEVKPLQFTNS------------KLFL 1896

Query: 89   SHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTG 148
                  + +L +  L   DR  Y C  T  T    +VV   + E       V+ P +   
Sbjct: 1897 F----SNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEE------RVTSPRIEAA 1946

Query: 149  SGYGFTVPQGMRISLQCQARGSPPISYIW-------YKQQTNNQEPIKVATLSTLLFKPA 201
            S     V  G ++ L C A G P    +W         QQ      I V    +L     
Sbjct: 1947 SQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSV 2006

Query: 202  VIADSGSYFCTAKGQVGSE 220
               DSG Y C A+ ++G +
Sbjct: 2007 TEKDSGVYLCVARNKMGDD 2025



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 34/148 (22%), Positives = 58/148 (39%), Gaps = 13/148 (8%)

Query: 142  KPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK-------QQTNNQEPIKVATLS 194
            KP +  G    FT+P      L C+A G+P  +  W +        +      ++V    
Sbjct: 1647 KPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNG 1706

Query: 195  TLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPT-----TMTY 249
            TL  +   I D G Y C+A    G++ H  +   VV    ++L+ +T+  T     T+  
Sbjct: 1707 TLSIQRVEIQDRGQYLCSASNLFGTD-HLHVTLSVVSYPPRILERRTKEITVHSGSTVEL 1765

Query: 250  PLKATSTVKQSWDWTTDMDGYLGETSAG 277
              +A      +  W       + E+S G
Sbjct: 1766 KCRAEGRPSPTVTWILANQTVVSESSQG 1793



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 34/162 (20%), Positives = 62/162 (38%), Gaps = 15/162 (9%)

Query: 95   DVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFT 154
            D +L L  L + DR  Y C  +   P G   +  KI      ++  + P +         
Sbjct: 1802 DGTLVLHNLSIYDRGFYKCVAS--NPGGQDSLLVKI------QVIAAPPVILEQRRQVIV 1853

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI-------ADSG 207
               G  + L C A+G+P  S  W        +P++       LF    +       +D G
Sbjct: 1854 GTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRG 1913

Query: 208  SYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTMTY 249
            +Y C A    GSE+   ++    + +S  ++  ++  T + +
Sbjct: 1914 TYECIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNF 1955



 Score = 38.9 bits (89), Expect = 0.008
 Identities = 37/174 (21%), Positives = 70/174 (40%), Gaps = 20/174 (11%)

Query: 80   AKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLS 139
            A Y G     HK   + +L++  + + D + + C    +  +   VV+ ++ E+      
Sbjct: 2283 APYYGSRITVHK---NGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEM------ 2333

Query: 140  VSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWY----KQQTNNQEPIK--VATL 193
            + +PT             G   +L C   G+PP   IW      + +N  +  +  +A+ 
Sbjct: 2334 LRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASN 2393

Query: 194  STLLFKPAVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKTEAPTTM 247
             + +       D+G Y C A+ +VG      I K V+ +  +     T AP T+
Sbjct: 2394 GSFIISKTTREDAGKYRCAARNKVGY-----IEKLVILEIGQKPVILTYAPGTV 2442



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 30/134 (22%), Positives = 52/134 (38%), Gaps = 21/134 (15%)

Query: 107  DRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQ 166
            DR +Y C+   Q   G+ ++   +       +    P +T           G    L C 
Sbjct: 2500 DRGNYICKA--QNSVGHTLITVPVM------IVAYPPRITNRPPRSIVTRTGAAFQLHCV 2551

Query: 167  ARGSPPISYIWY-----------KQQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKG 215
            A G P     W            K++T+  E + +    TL+ +    +DSG Y CTAK 
Sbjct: 2552 ALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQ--GTLVIQNPQTSDSGIYKCTAKN 2609

Query: 216  QVGSEQHSDIVKFV 229
             +GS+  +  ++ +
Sbjct: 2610 PLGSDYAATYIQVI 2623



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 10/85 (11%)

Query: 142  KPTVTTGSGYGFTVPQGMRISLQCQARGSP--------PISYIWYKQQTNNQEPIKVATL 193
            KP + T +        G  +SL C + G P        P  Y+  + Q N +  +     
Sbjct: 2431 KPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILH--DN 2488

Query: 194  STLLFKPAVIADSGSYFCTAKGQVG 218
             TL+ K A   D G+Y C A+  VG
Sbjct: 2489 GTLVIKEATAYDRGNYICKAQNSVG 2513


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 36/132 (27%), Positives = 55/132 (41%), Gaps = 6/132 (4%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGY 151
            +PG   LQ+   + +D   YTC VT +   G  V    +  L    +S   P    G   
Sbjct: 1400 LPGTHGLQILNAQKEDAGQYTCVVTNEL--GEAVKNYHVEVLIPPSISKDDPLGEVGVKE 1457

Query: 152  GFTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLL-FKPAVIADSGS 208
              T      ++L+C++   PP +  WYK  Q       ++V     LL  +P  ++DSG 
Sbjct: 1458 VKT-KVNSTLTLECESWAVPPPTIRWYKDGQPVTPSSRLQVLGEGRLLQIQPTQVSDSGR 1516

Query: 209  YFCTAKGQVGSE 220
            Y C A    G +
Sbjct: 1517 YLCVATNVAGED 1528



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 61/248 (24%), Positives = 91/248 (36%), Gaps = 33/248 (13%)

Query: 23   LEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRDSSGDHIQQAKY 82
            + VP  +T P       P    P+   T V +         P  ++L+D  G+ +  A  
Sbjct: 782  VNVPPRITLP-------PSLPGPVLVNTPVRLTCNATGAPSPTLMWLKD--GNPVSPAGT 832

Query: 83   QGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSK 142
             G L V    PG   L L++    D   Y+C       +  Q V           L V  
Sbjct: 833  PG-LQV---FPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDV----------VLQVHM 878

Query: 143  PTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST----LLF 198
            P    G     +V     ++L+CQ+   PP    W+K      EP     LS     L  
Sbjct: 879  PPSILGEELNVSVVANESVALECQSHAMPPPVLSWWK-DGRPLEPRPGVHLSADKALLQV 937

Query: 199  KPAVIADSGSYFCTAKGQVG-SEQHSDIVKFVVK----DSSKLLKTKTEAPTTMTYPLKA 253
              A + D+G Y C A  Q G SE+H ++  +V        S  L  +   PT+++   + 
Sbjct: 938  DRADVWDAGHYTCEALNQAGRSEKHYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRG 997

Query: 254  TSTVKQSW 261
                K SW
Sbjct: 998  VPFPKISW 1005



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 44/179 (24%), Positives = 68/179 (37%), Gaps = 26/179 (14%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELR---VQKLSVSKPTVTTGSGYGFT 154
            LQLS L+      YTC           V  +   E R   V  + V+    ++G      
Sbjct: 1989 LQLSRLQPAQAGTYTC-----------VAENTQAEARKDFVVAVLVAPRIRSSGVAREHH 2037

Query: 155  VPQGMRISLQCQARGSPPISYIWYKQQT---NNQEPIKVATL--STLLFKPAVIADSGSY 209
            V +G  + L C+A G PP    W K  +    +  P     L   +L+ K    +D+G+Y
Sbjct: 2038 VLEGQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLRASDAGAY 2097

Query: 210  FCTAKGQVGSEQHSDIVKFVV-------KDSSKLLKTKTEAPTTMTYPLKATSTVKQSW 261
             C A    G +     V  +V        D S  L ++     TM  P++ +  +  SW
Sbjct: 2098 TCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSW 2156



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 32/127 (25%), Positives = 56/127 (44%), Gaps = 13/127 (10%)

Query: 98  LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
           LQ+  +++ D   YTC  T    +  + V  K+         +  P +  G      V +
Sbjct: 659 LQIEKVDLRDEGIYTCAATNLAGESKREVALKV---------LVPPNIEPGP-VNKAVLE 708

Query: 158 GMRISLQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLL-FKPAVIADSGSYFCTAK 214
              ++L+C A G PP    W+K  Q  ++   + V+    +L  + A ++D+GSY C A 
Sbjct: 709 NASVTLECLASGVPPPDVSWFKGHQPVSSWMGVTVSVDGRVLRIEQAQLSDAGSYRCVAS 768

Query: 215 GQVGSEQ 221
              GS +
Sbjct: 769 NVAGSTE 775



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/127 (27%), Positives = 48/127 (37%), Gaps = 12/127 (9%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQ+ST E+ D + Y C    Q         +K+  LRVQ      P +        T   
Sbjct: 1710 LQVSTAEVADAASYMCVAENQAGSA-----EKLFTLRVQV----PPRIAGLDLEQVTAIL 1760

Query: 158  GMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVATLSTLLFKPAVIADSGSYFCTAK 214
               +SL C     P     WYK     +  +E   +    TL    A ++DSG Y C A 
Sbjct: 1761 NSSVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGTHTLQLGRARLSDSGMYTCEAL 1820

Query: 215  GQVGSEQ 221
               G +Q
Sbjct: 1821 NAAGRDQ 1827



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 37/128 (28%), Positives = 53/128 (41%), Gaps = 16/128 (12%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVS-KPTVTTGS-GYGFT 154
            SL L  L   D   YTC      P G         + R+  ++V   PT+  G+ G G  
Sbjct: 2083 SLVLKGLRASDAGAYTCVA--HNPAGE--------DARLHTVNVLVPPTIKQGADGSGTL 2132

Query: 155  VPQ-GMRISLQCQARGSPPISYIWYKQQTN---NQEPIKVATLSTLLFKPAVIADSGSYF 210
            V + G  +++ C  RGSPPI   W K       +Q  +   +  TL      +AD+G + 
Sbjct: 2133 VSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGIFT 2192

Query: 211  CTAKGQVG 218
            C A    G
Sbjct: 2193 CVAASPAG 2200



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 34/131 (25%), Positives = 54/131 (41%), Gaps = 17/131 (12%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGF---- 153
            LQ+  +  ++   Y+C+ +      N+V  D +      +L V  P V  G         
Sbjct: 1615 LQIPLVRAENAGRYSCKAS------NEVGEDWLH----YELLVLTPPVILGDTEELVEEV 1664

Query: 154  TVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYF 210
            TV     +SLQC A G+P  +  W +         ++  L     L    A +AD+ SY 
Sbjct: 1665 TVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVLEDGQVLQVSTAEVADAASYM 1724

Query: 211  CTAKGQVGSEQ 221
            C A+ Q GS +
Sbjct: 1725 CVAENQAGSAE 1735



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 35/125 (28%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
            +L++S +++ D   +TC     +P G   V D+   L+VQ   V +P           V 
Sbjct: 2177 TLRISKVQLADAGIFTCVAA--SPAG---VADRNFTLQVQVPPVLEPVEFQND---VVVV 2228

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYFCTA 213
            +G  + L C+ARG P     W K    + EP+   +L    +L  +     DSG+Y C A
Sbjct: 2229 RGSLVELPCEARGVPLPLVSWMK----DGEPLLSQSLEQGPSLQLEAVGAGDSGTYSCVA 2284

Query: 214  KGQVG 218
              + G
Sbjct: 2285 VSEAG 2289



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 46/200 (23%), Positives = 73/200 (36%), Gaps = 21/200 (10%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            LQL  L   D   Y+C  T +   G+  V  ++    V  +    P V         +P 
Sbjct: 2446 LQLQALSTADSGDYSC--TARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLP- 2502

Query: 158  GMRISLQCQARGSPPISYIWYKQQT--NNQEP-IKVATLSTLLFKPAVIADSGSYFCTAK 214
                   CQA G P     W K +   + + P  ++    +L  +P +  D+G Y C A 
Sbjct: 2503 -------CQADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLAS 2555

Query: 215  GQVGSEQHSDIVKF-----VVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTDMDG 269
               GS++    ++      +    S L  T   A T    P +A+ + K    W  D   
Sbjct: 2556 NSAGSDRQGRDLRVLEPPAIAPSPSNLTLT---AHTPALLPCEASGSPKPLVVWWKDGQK 2612

Query: 270  YLGETSAGPGKSLPVFAIIL 289
                   G  + LP  A++L
Sbjct: 2613 LDFRLQQGAYRLLPSNALLL 2632



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 34/135 (25%), Positives = 55/135 (40%), Gaps = 13/135 (9%)

Query: 87   HVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVT 146
            H+ H++    SL +   E DD   Y C       +    V  K+  L +Q   V +    
Sbjct: 3072 HLRHQLQNG-SLTIHRTERDDAGRYQC-----LAENEMGVAKKVVILVLQSAPVFQV--- 3122

Query: 147  TGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--STLLFKPAVIA 204
                   TV  G  ++L+CQA G P  +  W +     +   ++ TL   +L  +     
Sbjct: 3123 --EPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETG 3180

Query: 205  DSGSYFCTAKGQVGS 219
            D+G+Y C A   +GS
Sbjct: 3181 DAGTYDCVAHNLLGS 3195



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 39/125 (31%), Positives = 52/125 (41%), Gaps = 11/125 (8%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQ 157
            L +  LE  D   YTC         N V R +    RV    +  P  TT  G   ++  
Sbjct: 2902 LLVKNLEGQDAGTYTCTAE------NAVGRAR---RRVHLTILVLPVFTTLPG-DRSLRL 2951

Query: 158  GMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVIA-DSGSYFCTAKGQ 216
            G R+ L+C ARGSP     W        E +      + L + AV   DSG+Y C A+ +
Sbjct: 2952 GDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENR 3011

Query: 217  VGSEQ 221
            VG  Q
Sbjct: 3012 VGRTQ 3016



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 27/85 (31%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 137  KLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK--QQTNNQE-PIKVATL 193
            +L V  P V        +  +G    L C+ARGSP  +  W K  Q  +  E    +   
Sbjct: 2840 RLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPS 2899

Query: 194  STLLFKPAVIADSGSYFCTAKGQVG 218
              LL K     D+G+Y CTA+  VG
Sbjct: 2900 GELLVKNLEGQDAGTYTCTAENAVG 2924



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 39/161 (24%), Positives = 62/161 (38%), Gaps = 25/161 (15%)

Query: 92   VPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKP----TVTT 147
            +PG  +LQL    + D   YTCE        N   RD+    ++ +LSV  P        
Sbjct: 1796 LPGTHTLQLGRARLSDSGMYTCEAL------NAAGRDQ----KLVQLSVLVPPAFRQAPR 1845

Query: 148  GSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLL-------FKP 200
            G      V  G +  L C+    P  +  WYK    + +P+ +A  +  L        + 
Sbjct: 1846 GPQDAVLVRVGDKAVLSCETDALPEPTVTWYK----DGQPLVLAQRTQALRGGQRLEIQE 1901

Query: 201  AVIADSGSYFCTAKGQVGSEQHSDIVKFVVKDSSKLLKTKT 241
            A ++D G Y C      G    +  +   V  + +  KT+T
Sbjct: 1902 AQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTET 1942



 Score = 36.6 bits (83), Expect = 0.041
 Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 24/132 (18%)

Query: 98   LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSV-SKPTVTTGSGYGFTVP 156
            LQ+   ++ D  HYTCE        NQ  R +    +   L+V   P       +  TV 
Sbjct: 935  LQVDRADVWDAGHYTCEAL------NQAGRSE----KHYNLNVWVAPVFPLRESHTLTVR 984

Query: 157  QGMRISLQCQARGSPPISYIWYKQQTNNQEPI--------KVATLSTLLF-KPAVIADSG 207
            +G   SL C+ RG P     W K    + +P+         V+ +  LL+   A +A  G
Sbjct: 985  EGHPTSLSCECRGVPFPKISWRK----DGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEG 1040

Query: 208  SYFCTAKGQVGS 219
            +Y C     VG+
Sbjct: 1041 TYTCECSNVVGN 1052



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 36/131 (27%), Positives = 50/131 (38%), Gaps = 16/131 (12%)

Query: 94  GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQV-VRDKITELRVQKLSVSKPTVTTGSGYG 152
           G   LQL   +  D   YTC+ +      N V   +K T L V       PT+    G  
Sbjct: 363 GGRQLQLGRAQSSDAGVYTCKAS------NAVGAAEKATRLDVYV----PPTIEGAGGRP 412

Query: 153 FTVPQ--GMRISLQCQARGSPPISYIWYKQ---QTNNQEPIKVATLSTLLFKPAVIADSG 207
           + V    G  ++L+C ARG P  +  W+ +      + E       S L  +    A SG
Sbjct: 413 YVVKAVAGRPVALECVARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSG 472

Query: 208 SYFCTAKGQVG 218
            Y C A    G
Sbjct: 473 LYSCVASSPAG 483



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 40/148 (27%), Positives = 61/148 (41%), Gaps = 14/148 (9%)

Query: 78  QQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQK 137
           +Q    G  H+  +  G V L+++   + D   Y C     +P G Q  RD   +LRV  
Sbjct: 255 RQPVLPGGPHLQVQEDGQV-LRITGSHVGDEGRYQCVAF--SPAGQQA-RD--FQLRVH- 307

Query: 138 LSVSKPTVTTGSGYG-FTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--- 193
              + PT+   +  G   V +   + L C+ARG P  +  W+K         KV      
Sbjct: 308 ---APPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALLPTSTKVVYTRGG 364

Query: 194 STLLFKPAVIADSGSYFCTAKGQVGSEQ 221
             L    A  +D+G Y C A   VG+ +
Sbjct: 365 RQLQLGRAQSSDAGVYTCKASNAVGAAE 392



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 32/131 (24%), Positives = 49/131 (37%), Gaps = 7/131 (5%)

Query: 161  ISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--STLLFKPAVIADSGSYFCTAKGQVG 218
            + L C+A G P  +  W K+  N    +    L    L    A   D+G+Y C AK   G
Sbjct: 2774 VLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAG 2833

Query: 219  SEQHSD--IVKFVVKDSSKLLKTKTEAPTTMTYPLKATSTVKQSWDWTTD---MDGYLGE 273
            S       +V+      + L    T   +    P KA  + + +  W  D   + G  G+
Sbjct: 2834 SAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGK 2893

Query: 274  TSAGPGKSLPV 284
             +  P   L V
Sbjct: 2894 FTIQPSGELLV 2904



 Score = 33.1 bits (74), Expect = 0.45
 Identities = 34/132 (25%), Positives = 52/132 (39%), Gaps = 21/132 (15%)

Query: 94   GDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGF 153
            G  +LQ + +  +D   Y C   W     N+V R +     V  + V +  V  G  + +
Sbjct: 2987 GGSTLQRAAVSREDSGTYVC---WAE---NRVGRTQA----VSFVHVKEAPVLQGEAFSY 3036

Query: 154  TV-PQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL------STLLFKPAVIADS 206
             V P G  I L C  RG P     W K       P++ + L       +L        D+
Sbjct: 3037 LVEPVGGSIQLDCVVRGDPVPDIHWIKDGL----PLRGSHLRHQLQNGSLTIHRTERDDA 3092

Query: 207  GSYFCTAKGQVG 218
            G Y C A+ ++G
Sbjct: 3093 GRYQCLAENEMG 3104



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 31/135 (22%), Positives = 52/135 (38%), Gaps = 28/135 (20%)

Query: 97   SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYG--FT 154
            SLQL  +   D   Y+C    +  +            R  +L+V +P     SG     +
Sbjct: 2266 SLQLEAVGAGDSGTYSCVAVSEAGEAR----------RHFQLTVMEPPHIEDSGQPTELS 2315

Query: 155  VPQGMRISLQCQARGSPPISYIWYK------QQTNNQEPIKVATLSTLLFKPAVIADSGS 208
            +  G  + L C A+G+P  +  W+K      +  NN    +V            + D+G 
Sbjct: 2316 LTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATRVLR----------VRDAGL 2365

Query: 209  YFCTAKGQVGSEQHS 223
            Y C A+   G+ + S
Sbjct: 2366 YTCLAESPAGAIEKS 2380



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 32/113 (28%), Positives = 51/113 (45%), Gaps = 13/113 (11%)

Query: 111 YTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYG-FTVPQGMRISLQCQARG 169
           Y+C  +  +P G  V++  + E++V       P +    G G  T   G  + L CQA G
Sbjct: 474 YSCVAS--SPAGEAVLQYSV-EVQVP------PQLLVAEGLGQVTTIVGQPLELPCQASG 524

Query: 170 SPPISYIWYKQQTNNQE--PIKVATLSTLLFKPAVIAD-SGSYFCTAKGQVGS 219
           SP  +  W +     +E   ++VA+  T L    V  D SG + C A  + G+
Sbjct: 525 SPVPTIQWLQNGRPAEELAGVQVASQGTTLHIDHVELDHSGLFACQATNEAGT 577



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 21/80 (26%), Positives = 37/80 (46%), Gaps = 11/80 (13%)

Query: 161  ISLQCQARGSPPISYIWYKQQTNNQEPIKVATLSTLLFKPAVI-------ADSGSYFCTA 213
            ++L C+A G PP +  W++     +EP+     + LL    ++        DSG Y C A
Sbjct: 1179 LTLLCEAMGIPPPAIRWFR----GEEPVSPGEDTYLLAGGWMLKMTQTQEQDSGLYSCLA 1234

Query: 214  KGQVGSEQHSDIVKFVVKDS 233
              + G  + +  V+ +V  S
Sbjct: 1235 SNEAGEARRNFSVEVLVPPS 1254



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 34/129 (26%), Positives = 52/129 (40%), Gaps = 29/129 (22%)

Query: 103  LEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGM-RI 161
            L + D   YTC    ++P G     +K   +RVQ    + P +    G  F V     ++
Sbjct: 2358 LRVRDAGLYTCLA--ESPAG---AIEKSFRVRVQ----APPNIVGPRGPRFVVGLAPGQL 2408

Query: 162  SLQCQARGSPPISYIWYK------QQTNNQEP-----IKVATLSTLLFKPAVIADSGSYF 210
             L+C     P     W++      +  + Q P     +++  LST        ADSG Y 
Sbjct: 2409 VLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST--------ADSGDYS 2460

Query: 211  CTAKGQVGS 219
            CTA+   GS
Sbjct: 2461 CTARNAAGS 2469



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 4/59 (6%)

Query: 165 CQARGSPPISYIWYK----QQTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVGS 219
           C   G+P     W K    +  + Q  + V    +L       ADSG Y C A  +VGS
Sbjct: 24  CGTHGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADSGDYECQATNEVGS 82



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 24/98 (24%), Positives = 40/98 (40%), Gaps = 4/98 (4%)

Query: 125  VVRDKITEL-RVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYK---Q 180
            VV +++ E  R+ +++V  P         FTV     + L C + G P  +  W K   Q
Sbjct: 2646 VVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQ 2705

Query: 181  QTNNQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVG 218
                    +V+    L    A+   +G Y C+A+   G
Sbjct: 2706 LGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 2743



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 18/61 (29%), Positives = 27/61 (44%), Gaps = 3/61 (4%)

Query: 163  LQCQARGSPPISYIWYK--QQTNNQEPIKVATLSTLLFKPAVIAD-SGSYFCTAKGQVGS 219
            L C     PP    WY+  Q  +  + + V     +L  P V A+ +G Y C A  +VG 
Sbjct: 1579 LYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGE 1638

Query: 220  E 220
            +
Sbjct: 1639 D 1639


>gi|24111244 MAM domain containing glycosylphosphatidylinositol
           anchor 1 [Homo sapiens]
          Length = 955

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 42/168 (25%), Positives = 72/168 (42%), Gaps = 20/168 (11%)

Query: 55  KWLVQRGSDPVTIFLRDSSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCE 114
           +++ +RGSD ++   +D+  D  +    QG   V         L+L  L   D + YTC+
Sbjct: 166 RFIWKRGSDTLS-HSQDNGVDIYEPLYTQGETKV---------LKLKNLRPQDYASYTCQ 215

Query: 115 VTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPIS 174
           V+ +   G   + DK    R+   + + P +         V  G  +++QC   G  P+ 
Sbjct: 216 VSVRNVCG---IPDKAITFRLTN-TTAPPALKLSVNETLVVNPGENVTVQCLLTGGDPLP 271

Query: 175 YIWYKQQTNNQEPIKVATLS---TLLFKPAVIADSGSYFCTAKGQVGS 219
            +   Q ++   P+ +  L+   TL        DSG Y CTA   VG+
Sbjct: 272 QL---QWSHGPGPLPLGALAQGGTLSIPSVQARDSGYYNCTATNNVGN 316



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 6/82 (7%)

Query: 97  SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGF-TV 155
           SL+L  L   D   Y C  ++        V D   E+ +   +V  PT++   G    TV
Sbjct: 399 SLELIDLHFSDYGTYLCMASFP----GAPVPDLSVEVNISSETVP-PTISVPKGRAVVTV 453

Query: 156 PQGMRISLQCQARGSPPISYIW 177
            +G    LQC+ RG P    +W
Sbjct: 454 REGSPAELQCEVRGKPRPPVLW 475



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 17/68 (25%), Positives = 29/68 (42%), Gaps = 2/68 (2%)

Query: 153 FTVPQGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATL--STLLFKPAVIADSGSYF 210
           +T+ +G  + LQC   G P     W K   +  +  +  ++   TL  +       G Y+
Sbjct: 48  YTIREGDTLMLQCLVTGHPRPQVRWTKTAGSASDKFQETSVFNETLRIERIARTQGGRYY 107

Query: 211 CTAKGQVG 218
           C A+  VG
Sbjct: 108 CKAENGVG 115


>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
          Length = 316

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 22/143 (15%)

Query: 87  HVSHKVPGDVS----LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSK 142
           H+S K  G VS    L++  +  +    Y C  +      N V    +  ++V   +V+ 
Sbjct: 171 HISPKAVGFVSEDEYLEIQGITREQSGDYECSAS------NDVAAPVVRRVKV---TVNY 221

Query: 143 PT-VTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVAT---LST 195
           P  ++   G G  VP G + +LQC+A   P   + WYK        ++ +KV     LS 
Sbjct: 222 PPYISEAKGTG--VPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSK 279

Query: 196 LLFKPAVIADSGSYFCTAKGQVG 218
           L+F      D G+Y C A  ++G
Sbjct: 280 LIFFNVSEHDYGNYTCVASNKLG 302



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 35/126 (27%), Positives = 52/126 (41%), Gaps = 18/126 (14%)

Query: 97  SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
           S+++  +++ D   YTC V  QT +  +  R     L VQ   VS   V   S    ++ 
Sbjct: 99  SIEIQNVDVYDEGPYTCSV--QTDNHPKTSR---VHLIVQ---VSPKIVEISSD--ISIN 148

Query: 157 QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST---LLFKPAVIADSGSYFCTA 213
           +G  ISL C A G P  +  W      +  P  V  +S    L  +      SG Y C+A
Sbjct: 149 EGNNISLTCIATGRPEPTVTW-----RHISPKAVGFVSEDEYLEIQGITREQSGDYECSA 203

Query: 214 KGQVGS 219
              V +
Sbjct: 204 SNDVAA 209


>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
          Length = 344

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 22/143 (15%)

Query: 87  HVSHKVPGDVS----LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSK 142
           H+S K  G VS    L++  +  +    Y C  +      N V    +  ++V   +V+ 
Sbjct: 171 HISPKAVGFVSEDEYLEIQGITREQSGDYECSAS------NDVAAPVVRRVKV---TVNY 221

Query: 143 PT-VTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVAT---LST 195
           P  ++   G G  VP G + +LQC+A   P   + WYK        ++ +KV     LS 
Sbjct: 222 PPYISEAKGTG--VPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSK 279

Query: 196 LLFKPAVIADSGSYFCTAKGQVG 218
           L+F      D G+Y C A  ++G
Sbjct: 280 LIFFNVSEHDYGNYTCVASNKLG 302



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 35/126 (27%), Positives = 52/126 (41%), Gaps = 18/126 (14%)

Query: 97  SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
           S+++  +++ D   YTC V  QT +  +  R     L VQ   VS   V   S    ++ 
Sbjct: 99  SIEIQNVDVYDEGPYTCSV--QTDNHPKTSR---VHLIVQ---VSPKIVEISSD--ISIN 148

Query: 157 QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST---LLFKPAVIADSGSYFCTA 213
           +G  ISL C A G P  +  W      +  P  V  +S    L  +      SG Y C+A
Sbjct: 149 EGNNISLTCIATGRPEPTVTW-----RHISPKAVGFVSEDEYLEIQGITREQSGDYECSA 203

Query: 214 KGQVGS 219
              V +
Sbjct: 204 SNDVAA 209


>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
          Length = 344

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/143 (27%), Positives = 63/143 (44%), Gaps = 22/143 (15%)

Query: 87  HVSHKVPGDVS----LQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSK 142
           H+S K  G VS    L++  +  +    Y C  +      N V    +  ++V   +V+ 
Sbjct: 171 HISPKAVGFVSEDEYLEIQGITREQSGDYECSAS------NDVAAPVVRRVKV---TVNY 221

Query: 143 PT-VTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQQ---TNNQEPIKVAT---LST 195
           P  ++   G G  VP G + +LQC+A   P   + WYK        ++ +KV     LS 
Sbjct: 222 PPYISEAKGTG--VPVGQKGTLQCEASAVPSAEFQWYKDDKRLIEGKKGVKVENRPFLSK 279

Query: 196 LLFKPAVIADSGSYFCTAKGQVG 218
           L+F      D G+Y C A  ++G
Sbjct: 280 LIFFNVSEHDYGNYTCVASNKLG 302



 Score = 30.4 bits (67), Expect = 2.9
 Identities = 35/126 (27%), Positives = 52/126 (41%), Gaps = 18/126 (14%)

Query: 97  SLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFTVP 156
           S+++  +++ D   YTC V  QT +  +  R     L VQ   VS   V   S    ++ 
Sbjct: 99  SIEIQNVDVYDEGPYTCSV--QTDNHPKTSR---VHLIVQ---VSPKIVEISSD--ISIN 148

Query: 157 QGMRISLQCQARGSPPISYIWYKQQTNNQEPIKVATLST---LLFKPAVIADSGSYFCTA 213
           +G  ISL C A G P  +  W      +  P  V  +S    L  +      SG Y C+A
Sbjct: 149 EGNNISLTCIATGRPEPTVTW-----RHISPKAVGFVSEDEYLEIQGITREQSGDYECSA 203

Query: 214 KGQVGS 219
              V +
Sbjct: 204 SNDVAA 209


>gi|10864029 junctional adhesion molecule 2 precursor [Homo sapiens]
          Length = 298

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 34/138 (24%), Positives = 53/138 (38%), Gaps = 21/138 (15%)

Query: 95  DVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKITELRVQKLSVSKPTVTTGSGYGFT 154
           D ++++  +   D   Y CEV+  +  G  +  D +T      L V             +
Sbjct: 91  DFNIRIKNVTRSDAGKYRCEVSAPSEQGQNLEEDTVT------LEVLVAPAVPSCEVPSS 144

Query: 155 VPQGMRISLQCQAR-GSPPISYIWYK-------------QQTNNQEPIKVATLSTLLFKP 200
              G  + L+CQ + G+P   Y W+K             Q TN+   +   T  TL F  
Sbjct: 145 ALSGTVVELRCQDKEGNPAPEYTWFKDGIRLLENPRLGSQSTNSSYTMNTKT-GTLQFNT 203

Query: 201 AVIADSGSYFCTAKGQVG 218
               D+G Y C A+  VG
Sbjct: 204 VSKLDTGEYSCEARNSVG 221


>gi|126517478 peroxidasin homolog-like [Homo sapiens]
          Length = 1463

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 51/215 (23%), Positives = 77/215 (35%), Gaps = 39/215 (18%)

Query: 12  HLTVDTYGRPILEVPESVTGPWKGDVNLPCTYDPLQGYTQVLVKWLVQRGSDPVTIFLRD 71
           H TV      I++ P   T   K  V L           +  V+WL +   +P  + +  
Sbjct: 404 HGTVQAAANIIVQAPPQFTVTPKDQVVLE----------EHAVEWLCEADGNPPPVIVWT 453

Query: 72  SSGDHIQQAKYQGRLHVSHKVPGDVSLQLSTLEMDDRSHYTCEVTWQTPDGNQVVRDKIT 131
            +G    Q   +G+    H V    +L++      D+  Y C+               ++
Sbjct: 454 KTGG---QLPVEGQ----HTVLSSGTLRIDRAAQHDQGQYECQA--------------VS 492

Query: 132 ELRVQKLSVS---KP---TVTTGSGYGFTVPQGMRISLQCQARGSPPISYIWYKQ--QTN 183
            L V+K+SV    KP    V T      +V  G  I++ C A+G P     W K+  Q  
Sbjct: 493 SLGVKKVSVQLTVKPKALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQIT 552

Query: 184 NQEPIKVATLSTLLFKPAVIADSGSYFCTAKGQVG 218
                 V    TL    A   D G Y C A+   G
Sbjct: 553 ESGKFHVDDEGTLTIYDAGFPDQGRYECVARNSFG 587



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 33/147 (22%), Positives = 57/147 (38%), Gaps = 11/147 (7%)

Query: 130 ITELRVQKLSVSKPTVTTGSGYGFTVPQGMRISLQCQARGSPPISYIW----YKQQTNNQ 185
           +  + V++ +   P +T        VP G  +   C+A G+P    IW    +     + 
Sbjct: 221 VASVTVEEFNCQSPRITF-EPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDD 279

Query: 186 EPIKVATLSTLLFKPAVIADSGSYFCTAKGQVG-SEQHSDIVKF---VVKDSSKLLKTKT 241
             + V    TL+ +    +D G Y C A+   G ++  S ++++     K S  +    T
Sbjct: 280 TRLNVFDDGTLMIRNTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDT 339

Query: 242 EA--PTTMTYPLKATSTVKQSWDWTTD 266
           E    T+ T    AT        WT D
Sbjct: 340 EVLIGTSTTLECMATGHPHPLITWTRD 366


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,358,505
Number of Sequences: 37866
Number of extensions: 680908
Number of successful extensions: 3157
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 267
Number of HSP's that attempted gapping in prelim test: 2058
Number of HSP's gapped (non-prelim): 1050
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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