BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|6005824 Sec23-interacting protein p125 [Homo sapiens] (1000 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|6005824 Sec23-interacting protein p125 [Homo sapiens] 2026 0.0 gi|54792780 DDHD domain containing 2 [Homo sapiens] 754 0.0 gi|237757346 DDHD domain containing 1 isoform c [Homo sapiens] 114 5e-25 gi|237757342 DDHD domain containing 1 isoform a [Homo sapiens] 114 5e-25 gi|237757344 DDHD domain containing 1 isoform b [Homo sapiens] 112 2e-24 gi|195927015 phosphatidylinositol transfer protein, membrane-ass... 62 3e-09 gi|195927017 phosphatidylinositol transfer protein, membrane-ass... 61 5e-09 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 60 8e-09 gi|4809279 annexin VII isoform 2 [Homo sapiens] 57 1e-07 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 56 1e-07 gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 56 1e-07 gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 55 3e-07 gi|163965366 nascent polypeptide-associated complex alpha subuni... 55 3e-07 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 55 3e-07 gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 pre... 55 3e-07 gi|7706501 WW domain binding protein 11 [Homo sapiens] 55 3e-07 gi|33946327 nucleoporin 214kDa [Homo sapiens] 54 1e-06 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 54 1e-06 gi|4502111 annexin VII isoform 1 [Homo sapiens] 54 1e-06 gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 53 1e-06 gi|150170670 piccolo isoform 2 [Homo sapiens] 53 2e-06 gi|150378539 piccolo isoform 1 [Homo sapiens] 53 2e-06 gi|34304383 Usher syndrome 1G protein [Homo sapiens] 53 2e-06 gi|192807323 SWI/SNF-related matrix-associated actin-dependent r... 52 3e-06 gi|192807320 SWI/SNF-related matrix-associated actin-dependent r... 52 3e-06 gi|192807318 SWI/SNF-related matrix-associated actin-dependent r... 52 3e-06 gi|192807316 SWI/SNF-related matrix-associated actin-dependent r... 52 3e-06 gi|192807314 SWI/SNF-related matrix-associated actin-dependent r... 52 3e-06 gi|192807312 SWI/SNF-related matrix-associated actin-dependent r... 52 3e-06 gi|21071056 SWI/SNF-related matrix-associated actin-dependent re... 52 3e-06 >gi|6005824 Sec23-interacting protein p125 [Homo sapiens] Length = 1000 Score = 2026 bits (5248), Expect = 0.0 Identities = 1000/1000 (100%), Positives = 1000/1000 (100%) Query: 1 MAERKPNGGSGGASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASLLLPGEDSTDV 60 MAERKPNGGSGGASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASLLLPGEDSTDV Sbjct: 1 MAERKPNGGSGGASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASLLLPGEDSTDV 60 Query: 61 GEEDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTAL 120 GEEDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTAL Sbjct: 61 GEEDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTAL 120 Query: 121 PFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGY 180 PFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGY Sbjct: 121 PFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGY 180 Query: 181 NPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSP 240 NPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSP Sbjct: 181 NPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSP 240 Query: 241 AQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKEVEYKQLWMPFSVFDSLNLEEIY 300 AQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKEVEYKQLWMPFSVFDSLNLEEIY Sbjct: 241 AQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKEVEYKQLWMPFSVFDSLNLEEIY 300 Query: 301 NSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTDSRFIPYTE 360 NSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTDSRFIPYTE Sbjct: 301 NSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTDSRFIPYTE 360 Query: 361 EFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTR 420 EFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTR Sbjct: 361 EFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWGTTQDGQTR 420 Query: 421 PRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLR 480 PRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLR Sbjct: 421 PRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLR 480 Query: 481 THFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRFRHFTNETLLDIL 540 THFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRFRHFTNETLLDIL Sbjct: 481 THFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRFRHFTNETLLDIL 540 Query: 541 FYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLN 600 FYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLN Sbjct: 541 FYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGSLILFDILSNQKDLN 600 Query: 601 LSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTLQETLEALSLSE 660 LSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTLQETLEALSLSE Sbjct: 601 LSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTLQETLEALSLSE 660 Query: 661 YFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKLKKAASEKKAVAAT 720 YFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKLKKAASEKKAVAAT Sbjct: 661 YFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKLKKAASEKKAVAAT 720 Query: 721 STKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLD 780 STKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLD Sbjct: 721 STKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLD 780 Query: 781 FEPEIFFALGSPIAMFLTIRGVDRIDENYSLPTCKGFFNIYHPLDPVAYRLEPMIVPDLD 840 FEPEIFFALGSPIAMFLTIRGVDRIDENYSLPTCKGFFNIYHPLDPVAYRLEPMIVPDLD Sbjct: 781 FEPEIFFALGSPIAMFLTIRGVDRIDENYSLPTCKGFFNIYHPLDPVAYRLEPMIVPDLD 840 Query: 841 LKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQE 900 LKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQE Sbjct: 841 LKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQE 900 Query: 901 ELEKVANQIKEEEEKQVVEAEKVVESPDFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESF 960 ELEKVANQIKEEEEKQVVEAEKVVESPDFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESF Sbjct: 901 ELEKVANQIKEEEEKQVVEAEKVVESPDFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESF 960 Query: 961 NEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH 1000 NEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH Sbjct: 961 NEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQH 1000 >gi|54792780 DDHD domain containing 2 [Homo sapiens] Length = 711 Score = 754 bits (1947), Expect = 0.0 Identities = 403/772 (52%), Positives = 520/772 (67%), Gaps = 72/772 (9%) Query: 235 SSVQSPAQQQVPARPGAPSVQVPSPFLLQNQ-----YEPVQPHWFYCKEVEYKQLWMPFS 289 SSVQS +Q + P +PS S F L + YEPV PHWFYCK ++ K+ W+PF+ Sbjct: 2 SSVQSQQEQLSQSDP-SPSPNSCSSFELIDMDAGSLYEPVSPHWFYCKIIDSKETWIPFN 60 Query: 290 VFDSLNLEEIYNSVQPDPESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKG 349 DS LEE Y+S + VV TDGGRYDV+L +R+R A YW+E +EVRRCTWFYKG Sbjct: 61 SEDSQQLEEAYSSGKGCNGRVV-PTDGGRYDVHLGERMRYAVYWDELASEVRRCTWFYKG 119 Query: 350 DTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPD 409 D D++++PY+E S+ LE Y AVT ++W ++LE P+ E I++HNPK++V +QP + D Sbjct: 120 DKDNKYVPYSESSSQVLEETYMLAVTLDEWKKKLESPNREIIILHNPKLMVHYQPVAGSD 179 Query: 410 EWGTTQDGQTRPRVVKRGIDDNLDEIPDGEMPQVDHLVFVVHGIGPVCDLRFRSIIECVD 469 WG+T Q RPR VKRG+++ +I GE Q+DHLVFVVHGIGP CDLRFRSI++CV+ Sbjct: 180 GWGSTPTEQGRPRTVKRGVENISVDIHCGEPLQIDHLVFVVHGIGPACDLRFRSIVQCVN 239 Query: 470 DFRVVSLKLLRTHFKKSLDDGKVSRVEFLPVHWHSSLGGDATGVDRNIKKITLPSIGRFR 529 DFR VSL LL+THFKK+ ++ ++ RVEFLPV+WHS L +TGVD ++++ITLPSI R R Sbjct: 240 DFRSVSLNLLQTHFKKAQENQQIGRVEFLPVNWHSPL--HSTGVDVDLQRITLPSINRLR 297 Query: 530 HFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALFMSRNPDFKGGVSVAGHSLGSLIL 589 HFTN+T+LD+ FYNSPTYCQTIV+ V E+N ++ LF+ RNPDFKGGVS+AGHSLGSLIL Sbjct: 298 HFTNDTILDVFFYNSPTYCQTIVDTVASEMNRIYTLFLQRNPDFKGGVSIAGHSLGSLIL 357 Query: 590 FDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEKQMPEEPKLTLDESYDLVVENKEVLTL 649 FDIL+NQKD + G + EK +S ++V+ + TL Sbjct: 358 FDILTNQKD------------SLGDID----SEK-----------DSLNIVMYQGDTPTL 390 Query: 650 QETLEALSLSEYFSTFEKEKIDMESLLMCTVDDLKEMGIPLGPRKKIANFVEHKAAKLKK 709 +E L+ L LSE+F FEKEK+D E+L +CT DL+E+GIPLGPRKKI N+ + Sbjct: 391 EEDLKKLQLSEFFDIFEKEKVDKEALALCTDRDLQEIGIPLGPRKKILNYFSTR------ 444 Query: 710 AASEKKAVAATSTKGQEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGA 769 ++ G ++ A + A++P ES C SS N + +VG Sbjct: 445 ----------KNSMGIKRPAPQPASGANIPKESE---------FCSSSNTRNGDYLDVGI 485 Query: 770 GQVSVAYNSLDFEPEIFFALGSPIAMFLTIRGVDRIDENYSLPTCKGFFNIYHPLDPVAY 829 GQVSV Y L ++PEIFFA GSPI MFLT+RG+ RID NY PTCKGFFNIYHP DPVAY Sbjct: 486 GQVSVKYPRLIYKPEIFFAFGSPIGMFLTVRGLKRIDPNYRFPTCKGFFNIYHPFDPVAY 545 Query: 830 RLEPMIVPDLDLKAVLIPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFA 889 R+EPM+VP ++ + +LIPHHKGRKR+HLEL+E L+RM DLK + SL+ AW++ F Sbjct: 546 RIEPMVVPGVEFEPMLIPHHKGRKRMHLELREGLTRMSMDLKNNLLGSLRMAWKS---FT 602 Query: 890 RAHTSSTQLQEELEKVANQIKEEEEKQVVEAEKVVESPDFS---KDEDYLGKVGMLNGGR 946 RA + Q E E+ E E + E V + + S K+E VGMLNGG+ Sbjct: 603 RAPYPALQASETPEET-----EAEPESTSEKPSDVNTEETSVAVKEEVLPINVGMLNGGQ 657 Query: 947 RIDYVLQEKPIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQP 998 RIDYVLQEKPIESFNEYLFALQSHLCYWESEDT LL+LKEIY+T I +QP Sbjct: 658 RIDYVLQEKPIESFNEYLFALQSHLCYWESEDTVLLVLKEIYQTQGIFLDQP 709 >gi|237757346 DDHD domain containing 1 isoform c [Homo sapiens] Length = 900 Score = 114 bits (285), Expect = 5e-25 Identities = 132/524 (25%), Positives = 206/524 (39%), Gaps = 119/524 (22%) Query: 226 PPGSLPPVPSSVQ-------SPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKE 278 PP P VP++ SP +++ R G P+ + + + + P + WFY ++ Sbjct: 119 PPQQPPLVPTNSGGGGATGGSPGERK-RTRLGGPAAR--HRYEVVTELGPEEVRWFYKED 175 Query: 279 VEYKQLWMPFSVFDSLNLEEIYNSVQP--------------------------------- 305 K+ W PF +DSL +E + ++ Sbjct: 176 ---KKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDED 232 Query: 306 ------------DPESVVLGT------DGGRYDVYLYDRIRKAAYWEE-EPAEVRRCTWF 346 +PE V L GG Y+V + YW + + V R WF Sbjct: 233 RACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWF 292 Query: 347 YKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETI----VMHNPKVIVQF 402 D + P EE S +E E+ Q + ++I +H+ K+ Sbjct: 293 I----DGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDAVHSFKLSRNH 348 Query: 403 QPSSVPDEWGTTQDGQT----RPRVVKRGIDDN-----------LDEIPDGEMP-QVDHL 446 DE D T R K G ++E + P Q H+ Sbjct: 349 VDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHI 408 Query: 447 VFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLRTHFKKSLDDGKVSRVEFLPVHWHSSL 506 VFVVHGIG D II+ R + K+ HF + VEFLPV W S L Sbjct: 409 VFVVHGIGQKMDQG--RIIKNTAMMREAARKIEERHFSNH-----ATHVEFLPVEWRSKL 461 Query: 507 GGDATGVDRNIKKITLPSIGRFRHFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALF 566 D VD IT + R N + +DI++Y SP Y +V+ + E+N L++LF Sbjct: 462 TLDGDTVD----SITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLF 517 Query: 567 MSRNPDF--KGG-VSVAGHSLGSLILFDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEK 623 SRNPDF KGG VS+ HSLG +I +DI++ + L +QL +E+ Sbjct: 518 CSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRL-------------YEQLLQKEE 564 Query: 624 QMPEEPKLTLDESY---DLVVENKEVLTLQETLEALSLSEYFST 664 ++P+E ++ +E + +L + + + ++E L L S T Sbjct: 565 ELPDERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQT 608 Score = 61.2 bits (147), Expect = 5e-09 Identities = 30/64 (46%), Positives = 44/64 (68%), Gaps = 5/64 (7%) Query: 778 SLDFEPEIFFALGSPIAMFLTIRGV---DRIDENYSLPT--CKGFFNIYHPLDPVAYRLE 832 +L F+ E FF +GSP+A+FL +RG+ + +++ LP C NI+HP DPVAYRLE Sbjct: 610 ALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLE 669 Query: 833 PMIV 836 P+I+ Sbjct: 670 PLIL 673 >gi|237757342 DDHD domain containing 1 isoform a [Homo sapiens] Length = 872 Score = 114 bits (285), Expect = 5e-25 Identities = 132/524 (25%), Positives = 206/524 (39%), Gaps = 119/524 (22%) Query: 226 PPGSLPPVPSSVQ-------SPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKE 278 PP P VP++ SP +++ R G P+ + + + + P + WFY ++ Sbjct: 119 PPQQPPLVPTNSGGGGATGGSPGERK-RTRLGGPAAR--HRYEVVTELGPEEVRWFYKED 175 Query: 279 VEYKQLWMPFSVFDSLNLEEIYNSVQP--------------------------------- 305 K+ W PF +DSL +E + ++ Sbjct: 176 ---KKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDED 232 Query: 306 ------------DPESVVLGT------DGGRYDVYLYDRIRKAAYWEE-EPAEVRRCTWF 346 +PE V L GG Y+V + YW + + V R WF Sbjct: 233 RACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWF 292 Query: 347 YKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETI----VMHNPKVIVQF 402 D + P EE S +E E+ Q + ++I +H+ K+ Sbjct: 293 I----DGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDAVHSFKLSRNH 348 Query: 403 QPSSVPDEWGTTQDGQT----RPRVVKRGIDDN-----------LDEIPDGEMP-QVDHL 446 DE D T R K G ++E + P Q H+ Sbjct: 349 VDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHI 408 Query: 447 VFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLRTHFKKSLDDGKVSRVEFLPVHWHSSL 506 VFVVHGIG D II+ R + K+ HF + VEFLPV W S L Sbjct: 409 VFVVHGIGQKMDQG--RIIKNTAMMREAARKIEERHFSNH-----ATHVEFLPVEWRSKL 461 Query: 507 GGDATGVDRNIKKITLPSIGRFRHFTNETLLDILFYNSPTYCQTIVEKVGMEINHLHALF 566 D VD IT + R N + +DI++Y SP Y +V+ + E+N L++LF Sbjct: 462 TLDGDTVD----SITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLF 517 Query: 567 MSRNPDF--KGG-VSVAGHSLGSLILFDILSNQKDLNLSKCPGPLAVANGVVKQLHFQEK 623 SRNPDF KGG VS+ HSLG +I +DI++ + L +QL +E+ Sbjct: 518 CSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRL-------------YEQLLQKEE 564 Query: 624 QMPEEPKLTLDESY---DLVVENKEVLTLQETLEALSLSEYFST 664 ++P+E ++ +E + +L + + + ++E L L S T Sbjct: 565 ELPDERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQT 608 Score = 72.4 bits (176), Expect = 2e-12 Identities = 73/256 (28%), Positives = 102/256 (39%), Gaps = 51/256 (19%) Query: 778 SLDFEPEIFFALGSPIAMFLTIRGV---DRIDENYSLPT--CKGFFNIYHPLDPVAYRLE 832 +L F+ E FF +GSP+A+FL +RG+ + +++ LP C NI+HP DPVAYRLE Sbjct: 610 ALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLE 669 Query: 833 PMIVPDL-DLKAVLIPHHKGRKRLHLE--------------------------------- 858 P+I+ ++ V I + L E Sbjct: 670 PLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSPV 729 Query: 859 -----LKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEE 913 ES++ +G G S K L F+R SST E K E+E Sbjct: 730 LSRRHYGESITNIGKASILGAASIGKGLGGML--FSRFGRSSTTQSSETSK---DSMEDE 784 Query: 914 EKQVVEAEKVVESPDFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCY 973 +K V L RID+ L+E +ES Y A+ SH Y Sbjct: 785 KKPVASPSATTVGTQTLPHSSSGFLDSALELDHRIDFELREGLVES--RYWSAVTSHTAY 842 Query: 974 WESEDTALLLLKEIYR 989 W S D AL LL +Y+ Sbjct: 843 WSSLDVALFLLTFMYK 858 >gi|237757344 DDHD domain containing 1 isoform b [Homo sapiens] Length = 879 Score = 112 bits (280), Expect = 2e-24 Identities = 127/531 (23%), Positives = 205/531 (38%), Gaps = 126/531 (23%) Query: 226 PPGSLPPVPSSVQ-------SPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKE 278 PP P VP++ SP +++ R G P+ + + + + P + WFY ++ Sbjct: 119 PPQQPPLVPTNSGGGGATGGSPGERK-RTRLGGPAAR--HRYEVVTELGPEEVRWFYKED 175 Query: 279 VEYKQLWMPFSVFDSLNLEEIYNSVQP--------------------------------- 305 K+ W PF +DSL +E + ++ Sbjct: 176 ---KKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDED 232 Query: 306 ------------DPESVVLGT------DGGRYDVYLYDRIRKAAYWEE-EPAEVRRCTWF 346 +PE V L GG Y+V + YW + + V R WF Sbjct: 233 RACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWF 292 Query: 347 YKGDTDSRFIPYTEEFSEKLEAEYKKAVTTNQWHRRLEFPSGETIVMH-----NPKVIVQ 401 D + P EE S +E E+ Q + ++I N + Sbjct: 293 I----DGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDGSGINYSAVHS 348 Query: 402 FQPSSVPDEWGTTQD----GQTRPRVVKRGIDDNL------------------DEIPDGE 439 F+ S +W + + + R + L + + + Sbjct: 349 FKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDK 408 Query: 440 MPQVDHLVFVVHGIGPVCDLRFRSIIECVDDFRVVSLKLLRTHFKKSLDDGKVSRVEFLP 499 Q H+VFVVHGIG D II+ R + K+ HF + VEFLP Sbjct: 409 PSQTTHIVFVVHGIGQKMDQG--RIIKNTAMMREAARKIEERHFSNH-----ATHVEFLP 461 Query: 500 VHWHSSLGGDATGVDRNIKKITLPSIGRFRHFTNETLLDILFYNSPTYCQTIVEKVGMEI 559 V W S L D VD IT + R N + +DI++Y SP Y +V+ + E+ Sbjct: 462 VEWRSKLTLDGDTVD----SITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQEL 517 Query: 560 NHLHALFMSRNPDF--KGG-VSVAGHSLGSLILFDILSNQKDLNLSKCPGPLAVANGVVK 616 N L++LF SRNPDF KGG VS+ HSLG +I +DI++ + L + Sbjct: 518 NRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRL-------------YE 564 Query: 617 QLHFQEKQMPEEPKLTLDESY---DLVVENKEVLTLQETLEALSLSEYFST 664 QL +E+++P+E ++ +E + +L + + + ++E L L S T Sbjct: 565 QLLQKEEELPDERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQT 615 Score = 72.4 bits (176), Expect = 2e-12 Identities = 73/256 (28%), Positives = 102/256 (39%), Gaps = 51/256 (19%) Query: 778 SLDFEPEIFFALGSPIAMFLTIRGV---DRIDENYSLPT--CKGFFNIYHPLDPVAYRLE 832 +L F+ E FF +GSP+A+FL +RG+ + +++ LP C NI+HP DPVAYRLE Sbjct: 617 ALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLE 676 Query: 833 PMIVPDL-DLKAVLIPHHKGRKRLHLE--------------------------------- 858 P+I+ ++ V I + L E Sbjct: 677 PLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSPV 736 Query: 859 -----LKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEELEKVANQIKEEE 913 ES++ +G G S K L F+R SST E K E+E Sbjct: 737 LSRRHYGESITNIGKASILGAASIGKGLGGML--FSRFGRSSTTQSSETSK---DSMEDE 791 Query: 914 EKQVVEAEKVVESPDFSKDEDYLGKVGMLNGGRRIDYVLQEKPIESFNEYLFALQSHLCY 973 +K V L RID+ L+E +ES Y A+ SH Y Sbjct: 792 KKPVASPSATTVGTQTLPHSSSGFLDSALELDHRIDFELREGLVES--RYWSAVTSHTAY 849 Query: 974 WESEDTALLLLKEIYR 989 W S D AL LL +Y+ Sbjct: 850 WSSLDVALFLLTFMYK 865 >gi|195927015 phosphatidylinositol transfer protein, membrane-associated isoform a [Homo sapiens] Length = 1244 Score = 62.0 bits (149), Expect = 3e-09 Identities = 67/284 (23%), Positives = 111/284 (39%), Gaps = 47/284 (16%) Query: 725 QEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLDFEPE 784 + + +Q + A + S EP+R ++ C S E G S A LDF+ Sbjct: 640 EPEGSQNSLQAAPATTSSWEPRR------ASTAFCPPAASSEAPDGPSSTA--RLDFKVS 691 Query: 785 IFFALGSPIAMFLTIRG--VDRIDENYSLPTCKGFFNIYHPLDPVAYRLEPMIVPDLDLK 842 FF GSP+ + L +R + ++ P C+ +N++H DP A RLEP++ P Sbjct: 692 GFFLFGSPLGLVLALRKTVMPALEAAQMRPACEQIYNLFHAADPCASRLEPLLAPKFQAI 751 Query: 843 AVL-IPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEE 901 A L +P ++ L + S + +D Q T S+ EE Sbjct: 752 APLTVPRYQ-----KFPLGDGSSLLLADTLQ--------------------THSSLFLEE 786 Query: 902 LEKVANQIKEEEEKQVVEAEKVVESPDF-----SKDEDYLGKVGMLNGGRRIDYVLQ-EK 955 LE + + ++ P S + + + G +RIDY L + Sbjct: 787 LEMLVPSTPTSTSGAFWKGSELATDPPAQPAAPSTTSEVVKILERWWGTKRIDYSLYCPE 846 Query: 956 PIESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQ 999 + +F H YWES D +L+++ I E+PQ Sbjct: 847 ALTAFPTVTLPHLFHASYWESADVVAFILRQV-----IEKERPQ 885 >gi|195927017 phosphatidylinositol transfer protein, membrane-associated isoform b [Homo sapiens] Length = 1243 Score = 61.2 bits (147), Expect = 5e-09 Identities = 69/283 (24%), Positives = 110/283 (38%), Gaps = 46/283 (16%) Query: 725 QEQSAQKTKDMASLPSESNEPKRKLPVGACVSSVCVNYESFEVGAGQVSVAYNSLDFEPE 784 + + +Q + A + S EP+R ++ C S E G S A LDF+ Sbjct: 640 EPEGSQNSLQAAPATTSSWEPRR------ASTAFCPPAASSEAPDGPSSTA--RLDFKVS 691 Query: 785 IFFALGSPIAMFLTIRG-VDRIDENYSLPTCKGFFNIYHPLDPVAYRLEPMIVPDLDLKA 843 FF GSP+ + L +R V E P C+ +N++H DP A RLEP++ P A Sbjct: 692 GFFLFGSPLGLVLALRKTVMPALEAQMRPACEQIYNLFHAADPCASRLEPLLAPKFQAIA 751 Query: 844 VL-IPHHKGRKRLHLELKESLSRMGSDLKQGFISSLKSAWQTLNEFARAHTSSTQLQEEL 902 L +P ++ L + S + +D Q T S+ EEL Sbjct: 752 PLTVPRYQ-----KFPLGDGSSLLLADTLQ--------------------THSSLFLEEL 786 Query: 903 EKVANQIKEEEEKQVVEAEKVVESPDF-----SKDEDYLGKVGMLNGGRRIDYVLQ-EKP 956 E + + ++ P S + + + G +RIDY L + Sbjct: 787 EMLVPSTPTSTSGAFWKGSELATDPPAQPAAPSTTSEVVKILERWWGTKRIDYSLYCPEA 846 Query: 957 IESFNEYLFALQSHLCYWESEDTALLLLKEIYRTMNISPEQPQ 999 + +F H YWES D +L+++ I E+PQ Sbjct: 847 LTAFPTVTLPHLFHASYWESADVVAFILRQV-----IEKERPQ 884 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 60.5 bits (145), Expect = 8e-09 Identities = 61/200 (30%), Positives = 80/200 (40%), Gaps = 27/200 (13%) Query: 70 TSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQS----GFPKPLTALPFTTG 125 +SI T PQ + + +S P + PL+ AT Q+ P PL A P Sbjct: 585 SSIATPPPQ-----APPALASPPLQGLPSPPLSPLATPPPQAPPXLALP-PLQAPPSPPA 638 Query: 126 SQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIP--QPGYNPY 183 S +S +PS P AP + + + P P PP P P P P Sbjct: 639 SPPLSPLATPS-----PQAPNALAVHLLQ-APFSPPPSPPVQAPFSPPASPPVSPSATPP 692 Query: 184 RHTPGSSRANPYIAPPQ------LQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSV 237 P S A P PP + TP P A PP + PP+Q+ PP S P PS+ Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752 Query: 238 QSPAQQQVPARPGAPSVQVP 257 P +VP AP +QVP Sbjct: 753 PPP---RVPPLLAAPPLQVP 769 Score = 57.4 bits (137), Expect = 7e-08 Identities = 49/146 (33%), Positives = 59/146 (40%), Gaps = 11/146 (7%) Query: 114 PKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQ 173 P P PF S S SPS + APPS PS P+S P S P Sbjct: 669 PSPPVQAPF---SPPASPPVSPSATPPSQ-APPSLAAPPLQVPPSPPASPPMSPSATPPP 724 Query: 174 GIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPV 233 P P P P S A+P ++P TP P P + PP+Q+ PP SLP Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPMSP-----SATPPPRVPPLLAAPPLQVPPSPPASLPMS 779 Query: 234 PSSVQSPAQQQVPARPGAPSVQVPSP 259 P + P Q PA P +PSP Sbjct: 780 P--LAKPPPQAPPALATPPLQALPSP 803 Score = 56.6 bits (135), Expect = 1e-07 Identities = 69/255 (27%), Positives = 92/255 (36%), Gaps = 40/255 (15%) Query: 34 NVPFIPVTQASASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQTFSYFSQVSSSSDPF 93 ++P P Q S SPA + P + + S AP + + + S Sbjct: 462 SLPASPPLQTSLSPA--VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLA 519 Query: 94 GNIGQSP---LTTAATSVGQSGFPKPL--TALPFTTGSQDVSNAFSPSISKAQPGAPPSS 148 Q+P LTT S P PL + P TT + +P +A P + Sbjct: 520 PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP 579 Query: 149 LMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPG 208 S + + P PP+ QG+P P +P P +A P +A P LQ P Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPP--PQAPPXLALPPLQ--APPS 635 Query: 209 PPAHP--------------------------PPSGPPVQMYQMPPGSLPPVPSSVQSPAQ 242 PPA P PP PPVQ PP S PPV S P+ Sbjct: 636 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPPS- 693 Query: 243 QQVPARPGAPSVQVP 257 Q P AP +QVP Sbjct: 694 -QAPPSLAAPPLQVP 707 Score = 53.9 bits (128), Expect = 7e-07 Identities = 67/232 (28%), Positives = 87/232 (37%), Gaps = 22/232 (9%) Query: 41 TQASASPASLLLPGEDSTDVGEED-SFLGQTSIHT-SAPQTFSYFSQVSSSSDPFGNIGQ 98 TQ+S +P SL P T E+ L + T SAP T + + Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPP 573 Query: 99 SPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQ---PGAPPSSLMGINSY 155 SPLTT S P A P S + SP +S P APP + Sbjct: 574 SPLTTPPPETPSSIATPPPQAPP-ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQA 632 Query: 156 LPSQPSSLPPSYFGNQPQGIP--------QPGYNPYRHTPGSSRANPYIAPPQLQQCQTP 207 PS P+S P S P Q ++P P + +P +PP Sbjct: 633 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT-- 690 Query: 208 GPPAHPPPS--GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVP 257 PP+ PPS PP+Q+ PP S P PS+ P Q P AP +QVP Sbjct: 691 -PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQVP 738 Score = 50.4 bits (119), Expect = 8e-06 Identities = 69/236 (29%), Positives = 92/236 (38%), Gaps = 39/236 (16%) Query: 39 PVTQASASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQTFSYFSQVS--SSSDPFGNI 96 P QA SP +L + +T +G + + S QT + + S +S+ P Sbjct: 398 PSLQAPPSPLALSSL-QATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPP 456 Query: 97 GQSPLTTAAT-------SVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSL 149 Q+PL+ A+ S S PLT P S S++ P AP SSL Sbjct: 457 LQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS---------SLASHSPQAPLSSL 507 Query: 150 MGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTP-- 207 I L +Q S PPS P + P P + P +APP LQ P Sbjct: 508 --IMPPLETQSSLAPPS-LQTPPASLTTP---PLENLPS-------LAPPPLQTASAPLT 554 Query: 208 GPPAHPPPSGPPVQMYQMPPGSL----PPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 P PP P + Q PP L P PSS+ +P Q PA P +PSP Sbjct: 555 TPHLETPPCPAPCPL-QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSP 609 Score = 47.8 bits (112), Expect = 5e-05 Identities = 53/183 (28%), Positives = 70/183 (38%), Gaps = 20/183 (10%) Query: 92 PFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTG-SQDVSNAFSPSISKAQPGAPPSSLM 150 PF P++ +AT Q+ P L A P S S SPS + P APP Sbjct: 676 PFSPPASPPVSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSATPP-PQAPPPLAA 732 Query: 151 GINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPP 210 PS P+S P S P +P P P S A+ ++P Q P Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792 Query: 211 AHPP----PSGP----------PVQMYQMPPGSLPP--VPSSVQSPAQQQVPARPGAPSV 254 A PP PS P P M P + PP P + +P Q P+ P +P++ Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852 Query: 255 QVP 257 Q P Sbjct: 853 QAP 855 Score = 45.4 bits (106), Expect = 3e-04 Identities = 65/245 (26%), Positives = 88/245 (35%), Gaps = 27/245 (11%) Query: 22 LLFSSSATEFSFNVPFIPVTQA--SASP----ASLLLPGEDSTDVGEEDSFLGQTSIHTS 75 L SS S P + T + + SP ASL P ++ + S+ S Sbjct: 407 LALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPAS 466 Query: 76 APQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSP 135 P S VS S P L++ A+ Q+ PL++L + S+ P Sbjct: 467 PPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA----PLSSL-IMPPLETQSSLAPP 521 Query: 136 SISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPY 195 S+ PP+SL L + PS PP Q P P+ TP P Sbjct: 522 SLQ-----TPPASLT--TPPLENLPSLAPPPL-----QTASAPLTTPHLETPPCPAPCPL 569 Query: 196 IAPPQ---LQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAP 252 APP +TP A PPP PP + P LP P S + Q P P Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPA-LASPPLQGLPSPPLSPLATPPPQAPPXLALP 628 Query: 253 SVQVP 257 +Q P Sbjct: 629 PLQAP 633 Score = 43.1 bits (100), Expect = 0.001 Identities = 51/178 (28%), Positives = 65/178 (36%), Gaps = 22/178 (12%) Query: 100 PLTTAATSVGQSGFPKPLTALPFTTG-SQDVSNAFSPSISKAQPGAPPSSLMGINSYLPS 158 P++ +AT Q+ P PL A P S S SPS + P PP PS Sbjct: 715 PMSPSATPPPQA--PPPLAAPPLQVPPSPPASPPMSPSATPP-PRVPPLLAAPPLQVPPS 771 Query: 159 QPSSLPPSYFGNQPQGIP--------QPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPP 210 P+SLP S P P Q +P PG + +P + P + TP P Sbjct: 772 PPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP-MSPLATPPPQ 830 Query: 211 AHP---------PPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 A P PPS P Q P P P + S + + PG P SP Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888 Score = 42.0 bits (97), Expect = 0.003 Identities = 78/306 (25%), Positives = 114/306 (37%), Gaps = 50/306 (16%) Query: 1 MAERKPNGGSGGASTSSSGTNLLFSSSATEFSFNVPFIPVTQAS---ASPASLLLPGEDS 57 +AER GG GGA+ S + SA S N P A PA PG S Sbjct: 58 LAERA--GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115 Query: 58 TDVGEEDSF----LGQTSIHTSAPQTFSYFSQVSS-------------SSDPFGNIGQSP 100 + + LGQ + SA +T + + +S P Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175 Query: 101 LTTAATSVG-QSGFPKPLTAL---PFTTGSQ-DVSNAFSPSISKAQPGAP--PSSLMGIN 153 + + + G + G P+P + P T G + VS+A S ++ P A PS+ G+ Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235 Query: 154 -----SYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRA--NPYIAPPQLQQCQT 206 S S P+ G +G P+ +P + P +A P + PP+ Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 295 Query: 207 PGPP-----AHPPPSG-------PPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSV 254 GP A P PSG PP P +LPP P + +P P+ PS+ Sbjct: 296 LGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPP-LATPLPLAPPSPSAPPSL 354 Query: 255 Q-VPSP 259 Q +PSP Sbjct: 355 QTLPSP 360 >gi|4809279 annexin VII isoform 2 [Homo sapiens] Length = 488 Score = 56.6 bits (135), Expect = 1e-07 Identities = 79/301 (26%), Positives = 107/301 (35%), Gaps = 42/301 (13%) Query: 142 PGAPPSSLMGINSYLPS-QPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSS--RANPYIAP 198 PG PP+ Y P+ Q SS PPS P G P G Y P S A Y AP Sbjct: 4 PGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAP 63 Query: 199 PQLQQCQTPGPPAHPPPSG-------PPVQMYQMPPG-----SLPPVPSSVQSPAQQQVP 246 G P P P G PP Q + +PPG P PS QVP Sbjct: 64 GGYP--APGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVP 121 Query: 247 ARPGAPSVQVPSPFLLQNQYEPVQPHWFYCKEVEYKQLWMPFSVFDSLNLEEIYNSVQPD 306 G P Q+PS QY QP Y ++ + + VF ++L+ Y+S + Sbjct: 122 LPGGFPGGQMPS------QYPGGQP--TYPSQIN-TDSFSSYPVFSPVSLD--YSS---E 167 Query: 307 PESVVLGTDGGRYDVYLYDRIRKAAYWEEEPAEVRRCTWFYKGDTDSRFIPYTEEFSEKL 366 P +V T G +D IR AE+ R G + + S Sbjct: 168 PATVTQVTQGTIRPAANFDAIR--------DAEILRKAMKGFGTDEQAIVDVVANRSNDQ 219 Query: 367 EAEYKKAVTTNQWHRRLEFPSGETIVMHNPKVIVQFQPSSVPDEWG---TTQDGQTRPRV 423 + K A T+ ++ E ++ F P + D W Q T+ RV Sbjct: 220 RQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERV 279 Query: 424 V 424 + Sbjct: 280 L 280 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 56.2 bits (134), Expect = 1e-07 Identities = 73/272 (26%), Positives = 95/272 (34%), Gaps = 37/272 (13%) Query: 36 PFIPVTQASASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAP----QTFSYFSQVSSSSD 91 P P QA+A P + E LGQ T + F S Sbjct: 648 PQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQ 707 Query: 92 PFGNIGQSPLTTAATSVGQSGFPK---PLTALPFTTGS--------QDVSNAFSPSISKA 140 P + P + SV S P P A P G+ S A +P I A Sbjct: 708 PLS--AEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAA 765 Query: 141 QP--GAPPSSL--------MGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSS 190 P G PSS +G + +LPS + PPS ++PQ + +P P H Sbjct: 766 APLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPP 825 Query: 191 RANP-----YIAPPQL---QQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQ 242 +A P ++ QL P P A PP P Q P G LPP P S Sbjct: 826 QAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTS 885 Query: 243 QQVPARPGAPS-VQVPSPFLLQNQYEPVQ-PH 272 V + S + P+P Q Q+ P Q PH Sbjct: 886 SAVASSSETSSRLPAPTPSDFQLQFPPSQGPH 917 Score = 43.9 bits (102), Expect = 8e-04 Identities = 70/288 (24%), Positives = 103/288 (35%), Gaps = 58/288 (20%) Query: 6 PNGGSGGASTSSSGTNLLFSSSATEFSFNVPF-------IPVTQASASPASLLLPGEDST 58 PNG GGA+ ++ G + + N P +PV+ AS A P E T Sbjct: 218 PNGSPGGATAATLGLAPIQVVGQPVMALNTPTSQLLAKQVPVSGYLASAAG---PSEPVT 274 Query: 59 DVGEEDSFLG-----QTSIHTSAPQTF---SYFSQVSSSSDPFGNIGQSPLTTAATSVGQ 110 S G Q ++ + T S F ++S P G PL A +G Sbjct: 275 LASAGVSPQGAGLVIQKNLSAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAP-GLGS 333 Query: 111 SGF----------------PKPLTALP---FTTGSQDVSNAFSPSISKAQPGAPPSSLMG 151 S PKP LP + + + A + + +PGA P Sbjct: 334 SPLVPAPNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQ--- 390 Query: 152 INSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPG--P 209 P P +L G Q + G+ + +AN + PP T G P Sbjct: 391 -----PKAPQNLTFMAAGKAGQNVVLSGF-----PAPALQANVFKQPP----ATTTGAAP 436 Query: 210 PAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVP 257 P P P+ ++ + GS +P+ P Q Q PGAP+VQ+P Sbjct: 437 PQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQF-LLPGAPAVQLP 483 Score = 38.1 bits (87), Expect = 0.042 Identities = 39/138 (28%), Positives = 49/138 (35%), Gaps = 24/138 (17%) Query: 145 PPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRAN----------- 193 PP+S + P QP P S QP P P P H P SS ++ Sbjct: 845 PPASNPAPTAPGPPQPPLRPQS----QPPEGPLP---PAPHLPPSSTSSAVASSSETSSR 897 Query: 194 -PYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAP 252 P P Q P H P+ PP P + PP P PA P Sbjct: 898 LPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPK 957 Query: 253 SV-----QVPSPFLLQNQ 265 ++ QVPS +LQN+ Sbjct: 958 ALLERFHQVPSGIILQNK 975 Score = 33.1 bits (74), Expect = 1.3 Identities = 60/245 (24%), Positives = 82/245 (33%), Gaps = 71/245 (28%) Query: 47 PASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQTFSYF-----SQVSSSSDPF--GNIGQS 99 PA +LPG++ FL + PQ S Q+ +++ P G + + Sbjct: 461 PAQHMLPGQNQ--------FLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIAN 512 Query: 100 PLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAP-----PSSLMGINS 154 P+ T G PL+ P +A S + Q G P P SL + Sbjct: 513 PILTNQNLAG------PLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSL 566 Query: 155 YLPSQPS-------------SLPPSYFG--NQPQGIPQPGYNPYRHTPGSSRANPYIAPP 199 SQP+ +LPPS N P G+ QP TP ++ A P Sbjct: 567 PTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPA------TPAAATGE---AAP 617 Query: 200 QLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARP-----GAPSV 254 L P P Q PP P+P +Q P QQ P P P Sbjct: 618 VLT--------VQPAP--------QAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQA 661 Query: 255 QVPSP 259 P P Sbjct: 662 TTPQP 666 Score = 31.6 bits (70), Expect = 3.9 Identities = 41/190 (21%), Positives = 67/190 (35%), Gaps = 23/190 (12%) Query: 86 VSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAF-----SPSISKA 140 +++SS+ G PL+++A P T L G S + S S+S + Sbjct: 1212 IAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSS 1271 Query: 141 QPGAPPSSLMGINSYLPSQPSSLPP-------SYFGNQPQGIPQPGYNPYRHTPGSSRAN 193 + +S + + P + PP S G + + + G + H + Sbjct: 1272 SSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVH 1331 Query: 194 PYIAPPQLQQCQTPGP--PAHPPPSG---------PPVQMYQMPPGSLPPVPSSVQSPAQ 242 PP + P P P PPP+G PP + P G+ P P Sbjct: 1332 QPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTY 1391 Query: 243 QQVPARPGAP 252 ++ PGAP Sbjct: 1392 RENVGGPGAP 1401 >gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] Length = 464 Score = 56.2 bits (134), Expect = 1e-07 Identities = 49/147 (33%), Positives = 53/147 (36%), Gaps = 27/147 (18%) Query: 135 PSISKAQPGA--PPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRA 192 PS+ PG PP LM P P SLPP P G+P P P P Sbjct: 221 PSLPAGPPGVKRPPPPLMNGLPPRPPLPESLPPP----PPGGLPLPPMPPTGPAPSGPPG 276 Query: 193 NPYIAPPQLQQCQTPGPPAHPPPSG--PPVQMYQMP-PGSLPPVPS-------------S 236 P + PP P P HPP SG PP P PG PP P Sbjct: 277 PPQLPPPA-PGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPG 335 Query: 237 VQSPAQQQVPARPG----APSVQVPSP 259 V PA P PG AP V P+P Sbjct: 336 VHPPAPGVHPPAPGVHPPAPGVHPPAP 362 Score = 44.7 bits (104), Expect = 4e-04 Identities = 41/127 (32%), Positives = 49/127 (38%), Gaps = 13/127 (10%) Query: 143 GAPPSSLMGINSYLPSQPSSLPPSYFGNQP-QGI--PQPGYNPYRHTPGSSRANPYIAPP 199 G PS G P P PP+ + P G+ P PG +P PG P + PP Sbjct: 268 GPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHP--PAPGVHPPAPGVHPP 325 Query: 200 QLQQCQTPGPPAHPPPSG--PPVQMYQMP-PGSLPPVPSSVQSPAQQQVPARPG----AP 252 P P HPP G PP P PG PP P P+ P PG AP Sbjct: 326 T-SGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAP 384 Query: 253 SVQVPSP 259 +V +P Sbjct: 385 AVHPQAP 391 Score = 37.4 bits (85), Expect = 0.071 Identities = 39/124 (31%), Positives = 47/124 (37%), Gaps = 16/124 (12%) Query: 134 SPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRAN 193 +P + PG P + G++ P P PP G PQ PG +P P Sbjct: 340 APGVHPPAPGVHPPA-PGVH---PPAPGVHPPPSAGVHPQA---PGVHPA--APAVHPQA 390 Query: 194 PYIAPPQL-QQCQTPGPPAHPP---PSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARP 249 P + PP Q PG PP PS P V + PPG P P V P RP Sbjct: 391 PGVHPPAPGMHPQAPGVHPQPPGVHPSAPGV--HPQPPGVHPSNP-GVHPPTPMPPMLRP 447 Query: 250 GAPS 253 PS Sbjct: 448 PLPS 451 Score = 34.3 bits (77), Expect = 0.60 Identities = 33/107 (30%), Positives = 41/107 (38%), Gaps = 35/107 (32%) Query: 157 PSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS 216 P P SLP P G+ +P PP L P PP P S Sbjct: 217 PPAPPSLPAG-----PPGVKRP-------------------PPPLMNGLPPRPPL--PES 250 Query: 217 GPPVQMYQMPPGSLP--PVPSSVQSPAQQQVPAR--PGAPSVQVPSP 259 PP PPG LP P+P + +P+ P + P AP V P+P Sbjct: 251 LPPP-----PPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAP 292 >gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 preproprotein [Homo sapiens] Length = 331 Score = 55.5 bits (132), Expect = 3e-07 Identities = 54/152 (35%), Positives = 61/152 (40%), Gaps = 26/152 (17%) Query: 126 SQDVSNAFSPSISKAQPGAPPSSLMGINSYL-----PSQPSSLPPSYFGNQPQGIPQPG- 179 ++DVS SPS+ P P S G N P +P PP GN+PQG P PG Sbjct: 20 NEDVSQEESPSLIAGNPQGP--SPQGGNKPQGPPPPPGKPQG-PPPQGGNKPQGPPPPGK 76 Query: 180 ------YNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHP-PPSGPPVQMYQMPPGSLPP 232 +P S P PPQ Q GPP P P GPP Q P G PP Sbjct: 77 PQGPPPQGDKSRSPRSPPGKPQGPPPQGGN-QPQGPPPPPGKPQGPPPQGGNRPQG--PP 133 Query: 233 VPSSVQSPAQQQVPAR-----PGAPSVQVPSP 259 P Q P Q +R PG P Q P P Sbjct: 134 PPGKPQGPPPQGDKSRSPRSPPGKP--QGPPP 163 Score = 52.0 bits (123), Expect = 3e-06 Identities = 45/130 (34%), Positives = 50/130 (38%), Gaps = 17/130 (13%) Query: 143 GAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTP-GSSR-------ANP 194 G PP + P PP GNQPQG P P P P G +R P Sbjct: 79 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPGKP 138 Query: 195 YIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQ-----QVPARP 249 PPQ + ++P P P GPP Q P G PP P Q P Q Q P P Sbjct: 139 QGPPPQGDKSRSPRSPP-GKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGKKPQGPPPP 196 Query: 250 GAPSVQVPSP 259 G P Q P P Sbjct: 197 GKP--QGPPP 204 Score = 51.6 bits (122), Expect = 4e-06 Identities = 40/117 (34%), Positives = 43/117 (36%), Gaps = 11/117 (9%) Query: 143 GAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQ 202 G PP + P PP GNQPQG P P P P + P PP Sbjct: 140 GPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK-KPQGPPP--- 195 Query: 203 QCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 PG P PPP G + Q PPG P P Q P PG P Q P P Sbjct: 196 ----PGKPQGPPPQGDKSRSSQSPPGK-PQGPPPQGGNQPQGPPPPPGKP--QGPPP 245 Score = 51.6 bits (122), Expect = 4e-06 Identities = 45/131 (34%), Positives = 47/131 (35%), Gaps = 24/131 (18%) Query: 143 GAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQ 202 G PP +S P PP GNQPQG P P P P PP Sbjct: 201 GPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 260 Query: 203 QCQTPGPPAH----------PP--PSGPPVQMYQMPPGSLPPVPSSVQSP-----AQQQV 245 Q GPPA PP P GPP Q P G PP + Q P Q Q Sbjct: 261 Q----GPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 316 Query: 246 PARP---GAPS 253 P RP G PS Sbjct: 317 PPRPPQGGRPS 327 Score = 44.3 bits (103), Expect = 6e-04 Identities = 39/117 (33%), Positives = 45/117 (38%), Gaps = 24/117 (20%) Query: 141 QPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQ 200 QP PP P +P PP GN+PQG P PG G S++ +PP Sbjct: 229 QPQGPPPP--------PGKPQG-PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPG 279 Query: 201 LQQCQTPGPPAHPP--PSGPPV------QMYQMPPGSLPPVPSSVQSPAQQQVPARP 249 Q GPP P GPP Q Q PP P P P Q P+RP Sbjct: 280 KPQ----GPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGP---PRPPQGGRPSRP 329 Score = 35.0 bits (79), Expect = 0.35 Identities = 25/64 (39%), Positives = 27/64 (42%), Gaps = 12/64 (18%) Query: 157 PSQPSSLPPSYFGNQPQGIPQP-GYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPP 215 P +P PP GN PQG P P G NP + APP Q P PP P Sbjct: 278 PGKPQG-PPQQEGNNPQGPPPPAGGNPQQPQ----------APPAGQPQGPPRPPQGGRP 326 Query: 216 SGPP 219 S PP Sbjct: 327 SRPP 330 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 55.5 bits (132), Expect = 3e-07 Identities = 71/271 (26%), Positives = 103/271 (38%), Gaps = 39/271 (14%) Query: 6 PNGGSGGASTSSS-GTNLLFSSSATEFSFNVP----FIPVTQASASPASLLLPGEDSTDV 60 P SG ++T+SS GT + S + +V P + SA P + + G S+ V Sbjct: 771 PTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI--GNLSSPV 828 Query: 61 GE-EDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTA 119 E SFL + S+ + + + P G +P +A T + PK +T Sbjct: 829 SPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG----APTPSAVTPLS----PKGVTL 880 Query: 120 LPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIP--- 176 P T + V N P A P + + + S P + + P P+GIP Sbjct: 881 PPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA------PKGIPASP 934 Query: 177 --QPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS------GPPVQMYQMPPG 228 + P TP S + P P+ P PPA PPS P + PP Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKW----APTPPAATPPSPKGGPATPSPKGAPTPPA 990 Query: 229 SLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 + PP P PA P P+V PSP Sbjct: 991 ATPPSPKG--GPATPSPKGAPTPPAVTPPSP 1019 Score = 54.3 bits (129), Expect = 6e-07 Identities = 50/173 (28%), Positives = 64/173 (36%), Gaps = 17/173 (9%) Query: 99 SPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPS 158 +P T AAT PK A P G+ A PS K P PP P+ Sbjct: 1217 APTTPAATPPS----PKGGLATPSPKGAPTTPAATPPS-PKGGPATPPPK------GAPT 1265 Query: 159 QPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGP 218 P++ PPS G + NP TP S + P +PP+ P PPA PPS Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPK----GAPTPPAATPPS-- 1319 Query: 219 PVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQP 271 P PP P P +V P+ + P P P ++ P P Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPP 1372 Score = 47.8 bits (112), Expect = 5e-05 Identities = 53/181 (29%), Positives = 66/181 (36%), Gaps = 28/181 (15%) Query: 87 SSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPP 146 S ++ PF +P AAT G P A P G+ A PS K P P Sbjct: 1022 SPAATPFPKGASTP--PAATPPSPKGSP---AATPLPKGAPTTPAATLPS-PKGGPATP- 1074 Query: 147 SSLMGINSYLPSQPSSLPPSYFGN----QPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQ 202 SL G P+ P++ PPS G P+G P P G P+ P Sbjct: 1075 -SLKGA----PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTP 1129 Query: 203 QCQTPGPP---AHPPPSGPPVQMYQMPPGSLPPVP-SSVQSPAQQQVPARPGAPSVQVPS 258 P P A PPP G P P + PP P + +P + P P A PS Sbjct: 1130 AATPPSPKGGLATPPPKGAPT-----TPAATPPSPKGGLATPPPKGAPTTPAATP---PS 1181 Query: 259 P 259 P Sbjct: 1182 P 1182 Score = 47.0 bits (110), Expect = 9e-05 Identities = 52/173 (30%), Positives = 67/173 (38%), Gaps = 33/173 (19%) Query: 99 SPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPS 158 +P AAT G P A P G+ A +P K P A P + Sbjct: 985 APTPPAATPPSPKGGP----ATPSPKGAP-TPPAVTPPSPKGSPAATP-----FPKGAST 1034 Query: 159 QPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAP--PQLQQCQTP--------- 207 P++ PPS G+ P P P P TP ++ +P P P L+ TP Sbjct: 1035 PPAATPPSPKGS-PAATPLPKGAPT--TPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091 Query: 208 GPPAHPPPSGPPVQMYQMPPGSLPPVP-SSVQSPAQQQVPARPGAPSVQVPSP 259 G PA P P G P MPP + PP P + +P + P P A PSP Sbjct: 1092 GGPATPSPKGAP-----MPPAATPPSPKGGLATPPHKGAPTTPAATP---PSP 1136 Score = 47.0 bits (110), Expect = 9e-05 Identities = 59/213 (27%), Positives = 74/213 (34%), Gaps = 34/213 (15%) Query: 70 TSIHTSAPQTFSYFSQVSSSSDPFGNIGQ-----SPLTTAATSVGQSGF-----PKPLTA 119 T H AP T ++ P G + +P T AAT G PK Sbjct: 1119 TPPHKGAPTT-----PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPT 1173 Query: 120 LPFTTGSQDVSNAFSPSISKAQ--PGA-PPSSLMGINSY----LPSQPSSLPPSYFGNQP 172 P T +PS A P A PPS G+ + P+ P++ PPS G Sbjct: 1174 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1233 Query: 173 QGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS------GPPVQMYQMP 226 P+ TP S + P PP+ P PPA PPS PP + P Sbjct: 1234 TPSPKGAPTTPAATPPSPKGGPATPPPK----GAPTPPAATPPSLKGGLATPPHKGAPNP 1289 Query: 227 PGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 PP P PA P P+ PSP Sbjct: 1290 AVVTPPSPKG--GPATSPPKGAPTPPAATPPSP 1320 Score = 39.7 bits (91), Expect = 0.014 Identities = 46/169 (27%), Positives = 60/169 (35%), Gaps = 25/169 (14%) Query: 99 SPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPS 158 +P A T G P A PF G+ A PS K P A P + P+ Sbjct: 1008 APTPPAVTPPSPKGSP---AATPFPKGASTPPAATPPS-PKGSPAATP-----LPKGAPT 1058 Query: 159 QPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQ---LQQCQTPGPP----A 211 P++ PS G + P TP S + P P+ + TP P A Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLA 1118 Query: 212 HPPPSGPPVQMYQMPPGSLPPVP-SSVQSPAQQQVPARPGAPSVQVPSP 259 PP G P P + PP P + +P + P P A PSP Sbjct: 1119 TPPHKGAPT-----TPAATPPSPKGGLATPPPKGAPTTPAATP---PSP 1159 Score = 36.2 bits (82), Expect = 0.16 Identities = 41/160 (25%), Positives = 56/160 (35%), Gaps = 19/160 (11%) Query: 104 AATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSL 163 A V S PK A P G+ + A PS K P P S I Sbjct: 1480 APKQVATSSSPKKAPATPAPMGAPTLP-AVIPSSPKEVPATPSSRRDPIAPTATLLSKKT 1538 Query: 164 PPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMY 223 P + P+ P T S + P I P+ + P P+ S PP Sbjct: 1539 PATL-------APKEALIPPAMTVPSPKKTPAIPTPK----EAPATPSSKEASSPPAVTP 1587 Query: 224 QMPPGSLPP----VPSSVQSPAQQQVPARPGAPSVQVPSP 259 G+ P +P +V SP+ ++ P P+V PSP Sbjct: 1588 STYKGAPSPKELLIPPAVTSPSPKEAPT---PPAVTPPSP 1624 Score = 35.8 bits (81), Expect = 0.21 Identities = 45/177 (25%), Positives = 60/177 (33%), Gaps = 20/177 (11%) Query: 99 SPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSIS--------KAQPG----APP 146 +P T AAT G P A P G+ A PS+ K P PP Sbjct: 1240 APTTPAATPPSPKGGP----ATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPP 1295 Query: 147 SSLMGINSY----LPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQ 202 S G + P+ P++ PPS G+ P+ P TP S + P + Sbjct: 1296 SPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPS 1355 Query: 203 QCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 P P+ PP G PS + PA P +P+V SP Sbjct: 1356 SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412 Score = 32.0 bits (71), Expect = 3.0 Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 8/62 (12%) Query: 196 IAPPQLQQCQTPGPPAH-----PPPSGPPVQMYQMPPGSLPPVPSSVQS--PAQQQVPAR 248 +APP+ + TP A P P V PP SLP PS V + P QQ +P+ Sbjct: 1762 LAPPE-SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSS 1820 Query: 249 PG 250 PG Sbjct: 1821 PG 1822 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 55.1 bits (131), Expect = 3e-07 Identities = 63/241 (26%), Positives = 91/241 (37%), Gaps = 33/241 (13%) Query: 25 SSSATEFSFNVPFIPVTQASASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQTFSYFS 84 SS + + +P P + SA P+ LP +T + + LG ++ T S+ Sbjct: 328 SSLTCQLATPLPLAPPSP-SAPPSLQTLPSPPATPPSQATTSLGSPTLQA----THSFLP 382 Query: 85 QVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGA 144 S P SPL T + PL A P S +S +PS P A Sbjct: 383 -----SPPL-----SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS-----PQA 427 Query: 145 PPSSLMGINSYLPSQPSSLPPSYFGNQPQGIP--QPGYNPYRHTPGSSRANPYIAPPQ-- 200 P + + + P P PP P P P P P S A P PP Sbjct: 428 PNALAVHLLQ-APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPP 486 Query: 201 ----LQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQV 256 + TP P A PP + PP+Q+ + P P P ++ +P Q +P+ P + Q Sbjct: 487 ASPPMSPSATPPPQAPPPLAAPPLQLAKPP----PQAPPALATPPLQALPSPPASFPGQA 542 Query: 257 P 257 P Sbjct: 543 P 543 Score = 51.2 bits (121), Expect = 5e-06 Identities = 75/300 (25%), Positives = 106/300 (35%), Gaps = 50/300 (16%) Query: 2 AERKPNGGSG-----GASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASL--LLPG 54 A R+P+ G G S SSS T L + + + P P + P L L P Sbjct: 224 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283 Query: 55 EDSTDVGEEDSFLGQTS------------IHTSAPQTFSYFSQVSSSSDPFGNIGQSPLT 102 + + + LG S + + AP T SS + +PL Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLA----TPLP 339 Query: 103 TAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSS 162 A S + L + P T SQ ++ SP++ P L + + P P + Sbjct: 340 LAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 399 Query: 163 L--PPSYFGNQPQGIP--QPGYNPYRHTPGSSRAN----PYIAPPQLQQCQTP-GPPAHP 213 L PP P P P P P + + P+ +PP Q P PPA P Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-SPPPSPPVQAPFSPPASP 458 Query: 214 PPS--------------GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 P S PP+Q+ PP S P PS+ P Q P AP +Q+ P Sbjct: 459 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAPPPLAAPPLQLAKP 515 Score = 50.1 bits (118), Expect = 1e-05 Identities = 54/176 (30%), Positives = 70/176 (39%), Gaps = 29/176 (16%) Query: 94 GNIGQSPLTTAATSVG-QSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGI 152 G + SPL T + S QS P L A P ++ S A ++ P APPS Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSS-SLTCQLATPLPLAPPSPSAPPSL---- 351 Query: 153 NSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAH 212 LPS P++ PPS Q G +P + ++ P L TP P A Sbjct: 352 -QTLPSPPAT-PPS------QATTSLG------SPTLQATHSFLPSPPLSPLATPPPQAP 397 Query: 213 PPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQ--------QVPARPGAPSVQVPSPF 260 P + PP+Q PP S P P + SP Q P P PS V +PF Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPF 452 Score = 49.3 bits (116), Expect = 2e-05 Identities = 52/170 (30%), Positives = 64/170 (37%), Gaps = 32/170 (18%) Query: 114 PKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQ 173 P P PF S S SPS + APPS PS P+S P S P Sbjct: 444 PSPPVQAPF---SPPASPPVSPSATPPSQ-APPSLAAPPLQVPPSPPASPPMSPSATPPP 499 Query: 174 GIPQP-GYNPYRHTPGSSRANPYIAPPQLQQCQTP------------------GPPAHPP 214 P P P + +A P +A P LQ +P P A PP Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559 Query: 215 PSGPPV---QMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFL 261 P PPV + Q+PP PP ++Q+P + P PG P V P L Sbjct: 560 PQAPPVLAAPLLQVPPS--PPASPTLQAPRR---PPTPG-PDTSVSGPRL 603 Score = 42.0 bits (97), Expect = 0.003 Identities = 45/173 (26%), Positives = 59/173 (34%), Gaps = 9/173 (5%) Query: 92 PFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTG-SQDVSNAFSPSISKAQPGAPPSSLM 150 PF P++ +AT Q+ P L A P S S SPS + PP + Sbjct: 451 PFSPPASPPVSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508 Query: 151 GINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRAN----PYIAPPQLQQCQT 206 + L P PP+ Q +P P + P S A+ P PP Sbjct: 509 PLQ--LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566 Query: 207 PGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 P PPS P Q P P P + S + + PG P SP Sbjct: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619 >gi|41349486 proline-rich protein BstNI subfamily 1 isoform 3 preproprotein [Homo sapiens] Length = 178 Score = 55.1 bits (131), Expect = 3e-07 Identities = 54/159 (33%), Positives = 63/159 (39%), Gaps = 35/159 (22%) Query: 126 SQDVSNAFSPSISKAQPGAPPSSLMGINSYL-----PSQPSSLPPSYFGNQPQGIPQPGY 180 ++DVS SPS+ P P S G N P +P PP GN+PQG P PG Sbjct: 20 NEDVSQEESPSLIAGNPQGP--SPQGGNKPQGPPPPPGKPQG-PPPQGGNKPQGPPPPG- 75 Query: 181 NPYRHTPGSSRANPYIAPPQLQQCQTP------GPPAH----------PP--PSGPPVQM 222 P P ++ +PP Q P GPPA PP P GPP Q Sbjct: 76 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKPQGPPAQGGSKSQSARSPPGKPQGPPQQE 135 Query: 223 YQMPPGSLPPVPSSVQSP-----AQQQVPARP---GAPS 253 P G PP + Q P Q Q P RP G PS Sbjct: 136 GNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 174 Score = 35.4 bits (80), Expect = 0.27 Identities = 32/114 (28%), Positives = 40/114 (35%), Gaps = 21/114 (18%) Query: 147 SSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQT 206 SS +N + + S PS PQG G N + P PP Sbjct: 14 SSAQNLNEDVSQEES---PSLIAGNPQGPSPQGGNKPQGPP----------PP------- 53 Query: 207 PGPPAHPPPSGPPVQMYQMPPGSLP-PVPSSVQSPAQQQVPARPGAPSVQVPSP 259 PG P PPP G PPG P P +S + + P +P P Q P Sbjct: 54 PGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGKP 107 Score = 35.0 bits (79), Expect = 0.35 Identities = 25/64 (39%), Positives = 27/64 (42%), Gaps = 12/64 (18%) Query: 157 PSQPSSLPPSYFGNQPQGIPQP-GYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPP 215 P +P PP GN PQG P P G NP + APP Q P PP P Sbjct: 125 PGKPQG-PPQQEGNNPQGPPPPAGGNPQQPQ----------APPAGQPQGPPRPPQGGRP 173 Query: 216 SGPP 219 S PP Sbjct: 174 SRPP 177 >gi|7706501 WW domain binding protein 11 [Homo sapiens] Length = 641 Score = 55.1 bits (131), Expect = 3e-07 Identities = 47/160 (29%), Positives = 66/160 (41%), Gaps = 24/160 (15%) Query: 127 QDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSS-------LPPSYFGNQPQGIPQ-- 177 ++ S++ S + +Q APP S+ P P PP P G+P Sbjct: 375 KEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPLRPPGPPTGLPPGP 434 Query: 178 -PGYNPYRHTPGSSRAN---PYIAPPQLQQCQTPGPPAHPPPS--------GPPVQM-YQ 224 PG P+ PG P + PP + PGPP PPP GPP ++ Sbjct: 435 PPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPP 494 Query: 225 MPPGSLPPVPSSVQSPAQQQV-PARPGA-PSVQVPSPFLL 262 PPG PP P ++ P + PA PG P +P+P +L Sbjct: 495 APPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVL 534 >gi|33946327 nucleoporin 214kDa [Homo sapiens] Length = 2090 Score = 53.5 bits (127), Expect = 1e-06 Identities = 68/260 (26%), Positives = 100/260 (38%), Gaps = 46/260 (17%) Query: 10 SGGASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASLLLPGEDSTDVGEEDSFLGQ 69 +GGA T S F SS+ + S V P + +S S +S PG Sbjct: 475 AGGAPTVFS-----FGSSSLKSSATVTGEPPSYSSGSDSSKAAPGP-------------- 515 Query: 70 TSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDV 129 P TFS+ +S P + A+ S G SGF L + P V Sbjct: 516 ------GPSTFSFVPPSKASLAPTPAASPVAPSAASFSFGSSGFKPTLESTP-------V 562 Query: 130 SNAFSPSISKAQPGAPPSS---LMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHT 186 + +P+I+ +P PPS+ + ++ + +S P S + P P + + Sbjct: 563 PSVSAPNIA-MKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQSAPPMSPFSSASKPAAS 621 Query: 187 PGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQ-SPAQQQV 245 S P APP ++ P PSG Q GS PVPS VQ SP Sbjct: 622 GPLSHPTPLSAPPSSVPLKS---SVLPSPSGRSAQ------GSSSPVPSMVQKSPRITPP 672 Query: 246 PARPGAPSVQVPSPFLLQNQ 265 A+PG+P + P + + Q Sbjct: 673 AAKPGSPQAKSLQPAVAEKQ 692 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 53.5 bits (127), Expect = 1e-06 Identities = 59/222 (26%), Positives = 83/222 (37%), Gaps = 32/222 (14%) Query: 44 SASPASLLLPGEDSTDVGEEDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTT 103 SA P+ LP +T + + LG ++ T S+ S P SPL T Sbjct: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQA----THSFLP-----SPPL-----SPLAT 352 Query: 104 AATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSL 163 + PL A P S +S +PS P AP + + + P P Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPS-----PQAPNALAVHLLQ-APFSPPPS 406 Query: 164 PPSYFGNQPQGIP--QPGYNPYRHTPGSSRANPYIAPPQ------LQQCQTPGPPAHPPP 215 PP P P P P P S A P PP + TP P A PP Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466 Query: 216 SGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVP 257 + PP+Q+ + P P P ++ +P Q +P+ P + Q P Sbjct: 467 AAPPLQLAKPP----PQAPPALATPPLQALPSPPASFPGQAP 504 Score = 50.8 bits (120), Expect = 6e-06 Identities = 54/193 (27%), Positives = 73/193 (37%), Gaps = 31/193 (16%) Query: 94 GNIGQSPLTTAATSVGQSGFPKP----LTALPFTTGSQDVSNAFSPSISKAQPGAPPSSL 149 G + SPL T + S S P L + P T SQ ++ SP++ P L Sbjct: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 347 Query: 150 MGINSYLPSQPSSL--PPSYFGNQPQGIP--QPGYNPYRHTPGSSRAN----PYIAPPQL 201 + + P P +L PP P P P P P + + P+ +PP Sbjct: 348 SPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-SPPPS 406 Query: 202 QQCQTP-GPPAHPPPS--------------GPPVQMYQMPPGSLPPVPSSVQSPAQQQVP 246 Q P PPA PP S PP+Q+ PP S P PS+ P Q P Sbjct: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP---QAP 463 Query: 247 ARPGAPSVQVPSP 259 AP +Q+ P Sbjct: 464 PPLAAPPLQLAKP 476 Score = 49.3 bits (116), Expect = 2e-05 Identities = 52/170 (30%), Positives = 64/170 (37%), Gaps = 32/170 (18%) Query: 114 PKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQ 173 P P PF S S SPS + APPS PS P+S P S P Sbjct: 405 PSPPVQAPF---SPPASPPVSPSATPPSQ-APPSLAAPPLQVPPSPPASPPMSPSATPPP 460 Query: 174 GIPQP-GYNPYRHTPGSSRANPYIAPPQLQQCQTP------------------GPPAHPP 214 P P P + +A P +A P LQ +P P A PP Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520 Query: 215 PSGPPV---QMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFL 261 P PPV + Q+PP PP ++Q+P + P PG P V P L Sbjct: 521 PQAPPVLAAPLLQVPPS--PPASPTLQAPRR---PPTPG-PDTSVSGPRL 564 Score = 47.8 bits (112), Expect = 5e-05 Identities = 72/282 (25%), Positives = 97/282 (34%), Gaps = 25/282 (8%) Query: 2 AERKPNGGSG-----GASTSSSGTNLLFSSSATEFSFNVPFIPVTQASASPASLLLPGED 56 A R+P+ G G S SSS T L + + + P P + P L Sbjct: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274 Query: 57 STDVGEEDSFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTT----AATSVGQ-- 110 +D+ + +S T S + S S+ P SP T A TS+G Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334 Query: 111 -----SGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSS-LMGINSYLPSQPSSLP 164 S P P + P T A + +A P P S L + + P P++L Sbjct: 335 LQATHSFLPSPPLS-PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393 Query: 165 ----PSYFGNQPQGIPQPGYNPYRHTPGSSRANPYI-APPQLQQ--CQTPGPPAHPPPSG 217 + F P Q ++P P S A P APP L Q P P PP Sbjct: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453 Query: 218 PPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 P P L P + P Q PA P +PSP Sbjct: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495 Score = 45.8 bits (107), Expect = 2e-04 Identities = 56/200 (28%), Positives = 75/200 (37%), Gaps = 44/200 (22%) Query: 86 VSSSSDPFGNIGQSPLTTAAT--SVGQSGFPKP--LTAL---PFTTGSQDVSNAFSP--- 135 +SSS+ P + +S + T + PKP L AL T +D + A P Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292 Query: 136 -SISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRH------TPG 188 ++ P APPS PS P SL Q +P P P +P Sbjct: 293 SPLATPSPSAPPS---------PSAPPSL---------QTLPSPPATPPSQATTSLGSPT 334 Query: 189 SSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQ----- 243 + ++ P L TP P A P + PP+Q PP S P P + SP Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394 Query: 244 ---QVPARPGAPSVQVPSPF 260 Q P P PS V +PF Sbjct: 395 HLLQAPFSP-PPSPPVQAPF 413 Score = 42.0 bits (97), Expect = 0.003 Identities = 45/173 (26%), Positives = 59/173 (34%), Gaps = 9/173 (5%) Query: 92 PFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTG-SQDVSNAFSPSISKAQPGAPPSSLM 150 PF P++ +AT Q+ P L A P S S SPS + PP + Sbjct: 412 PFSPPASPPVSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 469 Query: 151 GINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRAN----PYIAPPQLQQCQT 206 + L P PP+ Q +P P + P S A+ P PP Sbjct: 470 PLQ--LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 527 Query: 207 PGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 P PPS P Q P P P + S + + PG P SP Sbjct: 528 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580 >gi|4502111 annexin VII isoform 1 [Homo sapiens] Length = 466 Score = 53.5 bits (127), Expect = 1e-06 Identities = 48/145 (33%), Positives = 54/145 (37%), Gaps = 17/145 (11%) Query: 142 PGAPPSSLMGINSYLPS-QPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSS--RANPYIAP 198 PG PP+ Y P+ Q SS PPS P G P G Y P S A Y AP Sbjct: 4 PGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAP 63 Query: 199 PQLQQCQTPGPPAHPPPSG-------PPVQMYQMPPG-----SLPPVPSSVQSPAQQQVP 246 G P P P G PP Q + +PPG P PS QVP Sbjct: 64 GGYP--APGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVP 121 Query: 247 ARPGAPSVQVPSPFLLQNQYEPVQP 271 G P Q+PS + P QP Sbjct: 122 LPGGFPGGQMPSQYPGGQPTYPSQP 146 >gi|7662236 TSC22 domain family, member 2 [Homo sapiens] Length = 780 Score = 53.1 bits (126), Expect = 1e-06 Identities = 56/192 (29%), Positives = 71/192 (36%), Gaps = 14/192 (7%) Query: 81 SYFSQVSSSSDPFGNIGQSPLTTAATSVG----QSGFPKPLTALPFTTGSQDVSN---AF 133 S F Q + G G S + A+ G +SG LTA+ S+ +S A Sbjct: 206 STFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEKMSQPTPAQ 265 Query: 134 SPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRAN 193 S S QP PP + G + + P + G QP P PG Sbjct: 266 PQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPGGQTLP 325 Query: 194 PY---IAPPQLQQCQTPGPPAHPPPSGPPVQMY----QMPPGSLPPVPSSVQSPAQQQVP 246 P +A P + PGP P + P Q Q+PPG L PV S QS QQ Sbjct: 326 PTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHV 385 Query: 247 ARPGAPSVQVPS 258 A PS PS Sbjct: 386 AGLQPPSPAQPS 397 Score = 37.4 bits (85), Expect = 0.071 Identities = 39/165 (23%), Positives = 53/165 (32%), Gaps = 27/165 (16%) Query: 98 QSPLTTAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPG---APPSSLMGINS 154 Q P +S G + P LP TG S + +QP AP + Sbjct: 389 QPPSPAQPSSTGAAASPATAATLPVGTGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQ 448 Query: 155 YLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPP 214 P QP+ +PP+ G G+ QP P + P PP P Sbjct: 449 VAPCQPTGVPPATVG----GVVQPCLGP------AGAGQPQSVPP--------------P 484 Query: 215 PSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSP 259 G + +P G VP PA P+ P + V P Sbjct: 485 QMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMP 529 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/206 (28%), Positives = 78/206 (37%), Gaps = 32/206 (15%) Query: 71 SIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVS 130 SI + P+ SQ + P Q+P T A Q +P T + V Sbjct: 238 SISSQQPEKIK--SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK 295 Query: 131 NAF----SPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHT 186 + P I + PG PP+ G + SQP P QP G+ +P Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPG---HEKSQPGPAKPPA---QPSGLTKP----LAQQ 345 Query: 187 PGSSRANPYIAPPQLQQCQTPGPPAHP-PPSGPPVQMY--------QMPPGSLPPVPSSV 237 PG+ + P + PP T PPA P P+ PP Q Q P +L P Sbjct: 346 PGTVK--PPVQPPG-----TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398 Query: 238 QSPAQQQVPARPGAPSVQVPSPFLLQ 263 ++PAQQ PA+P V P P Q Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQQ 424 Score = 51.2 bits (121), Expect = 5e-06 Identities = 49/168 (29%), Positives = 62/168 (36%), Gaps = 18/168 (10%) Query: 110 QSGFPKPLTALPFTTGSQDVSNAFSPSISKAQ---PGAPPSSLMGINSYLPSQPSSLPPS 166 Q G PKPL P G Q + A P+ + Q PG P+ G Q P Sbjct: 414 QVGTPKPLAQQP---GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP- 469 Query: 167 YFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMP 226 P +P P P + PG ++ P Q PG PP P + Sbjct: 470 -----PSQLPGPAKPPPQQ-PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523 Query: 227 PGSLPP---VPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQP 271 PGS P P S + AQQ PA+P A Q P +P+QP Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQTGSGKPLQP 569 Score = 39.7 bits (91), Expect = 0.014 Identities = 54/202 (26%), Positives = 65/202 (32%), Gaps = 48/202 (23%) Query: 103 TAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLM---GINSYLPSQ 159 T V G KP A P S S QPG P +L G+ Q Sbjct: 348 TVKPPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPG--PKALAQPPGVGKTPAQQ 404 Query: 160 PS-SLPPSYFGNQPQGIPQ-PGYNPYRHTPGSSRANPYIAPPQLQQCQTPGP-------- 209 P + PP+ P+ + Q PG PG ++ P Q GP Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464 Query: 210 -----------PAHPPPSGP-PVQMYQMPPGSLPP---VPSSVQSPAQQQVPARP----- 249 PA PPP P P + PGS P P S + P QQ PA+P Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524 Query: 250 ------------GAPSVQVPSP 259 PS Q PSP Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSP 546 Score = 38.9 bits (89), Expect = 0.024 Identities = 47/158 (29%), Positives = 56/158 (35%), Gaps = 24/158 (15%) Query: 94 GNIGQSPLTTAATSVGQSGFPKPLTALPFTTGS--QDVSNAFSPSISKAQPGA--PPSSL 149 G I TS Q+G KP + LP Q A P QPG+ PPS Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP---QQPGSAKPPSQQ 503 Query: 150 MGINSYLPSQPSSLPPSYFGNQPQGIPQPGYN-PYRHTPGSSRANPYIAPPQLQQCQTPG 208 G P QP PS PQ QPG P PGS++ + P Q Sbjct: 504 PGSTKPPPQQPGPAKPS-----PQ---QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555 Query: 209 PPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVP 246 P SG P+Q P V S + P Q +P Sbjct: 556 KPVSQTGSGKPLQP--------PTVSPSAKQPPSQGLP 585 Score = 37.4 bits (85), Expect = 0.071 Identities = 46/193 (23%), Positives = 66/193 (34%), Gaps = 22/193 (11%) Query: 68 GQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQ 127 G S P S+ + +P Q A Q KP T L + S Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDL--VSSSS 771 Query: 128 DVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQP---QGIPQPGYN--- 181 + PS SK Q A + + + S PP+ P + IP+P + Sbjct: 772 ATTKPDIPS-SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830 Query: 182 -----PYRHTPGSSRANPYIAPPQLQQCQT---PGPPAHPPPSGPPVQMYQMPPGSLPPV 233 P + G + +P + ++ QT P P A P P G P PPG P Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT-----PPGPRPTA 885 Query: 234 PSSVQSPAQQQVP 246 +V +P Q P Sbjct: 886 GQTVPTPQQSPKP 898 Score = 32.3 bits (72), Expect = 2.3 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 11/120 (9%) Query: 136 SISKAQPGAPPSSLMGINSYLPSQPSSLPPSYF-GNQPQGIPQPGYNPYRHTPGSS---- 190 S+S+ PPSS++ + L +YF + G +P +P S Sbjct: 2334 SLSETVFDHPPSSVIAL-----PMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPA 2388 Query: 191 RANPYIAPPQLQ-QCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARP 249 + P+ L Q P PP PPP PP PP P P P ++ A P Sbjct: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448 Score = 32.0 bits (71), Expect = 3.0 Identities = 40/142 (28%), Positives = 57/142 (40%), Gaps = 34/142 (23%) Query: 127 QDVSNAFSPSIS------KAQPGAPPSS----LMGINSYLPSQPSSLPPSYFGNQPQGIP 176 Q+ S FS ++ K+QP P + L G + + SQ S+L + QP Sbjct: 899 QEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST--AGQPGPHS 956 Query: 177 QPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLP--PVP 234 Q G PG AP + Q P P P GPP Q PP PV Sbjct: 957 QSG-------PG--------APMK----QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVK 997 Query: 235 SSVQSPAQQQV-PARPGAPSVQ 255 ++PA +++ P AP+V+ Sbjct: 998 KETKAPAAEKLEPKAEQAPTVK 1019 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 52.8 bits (125), Expect = 2e-06 Identities = 58/206 (28%), Positives = 78/206 (37%), Gaps = 32/206 (15%) Query: 71 SIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQDVS 130 SI + P+ SQ + P Q+P T A Q +P T + V Sbjct: 238 SISSQQPEKIK--SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVK 295 Query: 131 NAF----SPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQPQGIPQPGYNPYRHT 186 + P I + PG PP+ G + SQP P QP G+ +P Sbjct: 296 PSLPSPSKPPIQQPTPGKPPAQQPG---HEKSQPGPAKPPA---QPSGLTKP----LAQQ 345 Query: 187 PGSSRANPYIAPPQLQQCQTPGPPAHP-PPSGPPVQMY--------QMPPGSLPPVPSSV 237 PG+ + P + PP T PPA P P+ PP Q Q P +L P Sbjct: 346 PGTVK--PPVQPPG-----TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398 Query: 238 QSPAQQQVPARPGAPSVQVPSPFLLQ 263 ++PAQQ PA+P V P P Q Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQQ 424 Score = 51.2 bits (121), Expect = 5e-06 Identities = 49/168 (29%), Positives = 62/168 (36%), Gaps = 18/168 (10%) Query: 110 QSGFPKPLTALPFTTGSQDVSNAFSPSISKAQ---PGAPPSSLMGINSYLPSQPSSLPPS 166 Q G PKPL P G Q + A P+ + Q PG P+ G Q P Sbjct: 414 QVGTPKPLAQQP---GLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKP- 469 Query: 167 YFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMP 226 P +P P P + PG ++ P Q PG PP P + Sbjct: 470 -----PSQLPGPAKPPPQQ-PGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ 523 Query: 227 PGSLPP---VPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQP 271 PGS P P S + AQQ PA+P A Q P +P+QP Sbjct: 524 PGSTKPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQTGSGKPLQP 569 Score = 39.7 bits (91), Expect = 0.014 Identities = 54/202 (26%), Positives = 65/202 (32%), Gaps = 48/202 (23%) Query: 103 TAATSVGQSGFPKPLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLM---GINSYLPSQ 159 T V G KP A P S S QPG P +L G+ Q Sbjct: 348 TVKPPVQPPGTTKP-PAQPLGPAKPPAQQTGSEKPSSEQPG--PKALAQPPGVGKTPAQQ 404 Query: 160 PS-SLPPSYFGNQPQGIPQ-PGYNPYRHTPGSSRANPYIAPPQLQQCQTPGP-------- 209 P + PP+ P+ + Q PG PG ++ P Q GP Sbjct: 405 PGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQT 464 Query: 210 -----------PAHPPPSGP-PVQMYQMPPGSLPP---VPSSVQSPAQQQVPARP----- 249 PA PPP P P + PGS P P S + P QQ PA+P Sbjct: 465 GPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524 Query: 250 ------------GAPSVQVPSP 259 PS Q PSP Sbjct: 525 GSTKPPSQQPGSAKPSAQQPSP 546 Score = 38.9 bits (89), Expect = 0.024 Identities = 47/158 (29%), Positives = 56/158 (35%), Gaps = 24/158 (15%) Query: 94 GNIGQSPLTTAATSVGQSGFPKPLTALPFTTGS--QDVSNAFSPSISKAQPGA--PPSSL 149 G I TS Q+G KP + LP Q A P QPG+ PPS Sbjct: 447 GKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPP---QQPGSAKPPSQQ 503 Query: 150 MGINSYLPSQPSSLPPSYFGNQPQGIPQPGYN-PYRHTPGSSRANPYIAPPQLQQCQTPG 208 G P QP PS PQ QPG P PGS++ + P Q Sbjct: 504 PGSTKPPPQQPGPAKPS-----PQ---QPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555 Query: 209 PPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVP 246 P SG P+Q P V S + P Q +P Sbjct: 556 KPVSQTGSGKPLQP--------PTVSPSAKQPPSQGLP 585 Score = 37.4 bits (85), Expect = 0.071 Identities = 46/193 (23%), Positives = 66/193 (34%), Gaps = 22/193 (11%) Query: 68 GQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQSPLTTAATSVGQSGFPKPLTALPFTTGSQ 127 G S P S+ + +P Q A Q KP T L + S Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDL--VSSSS 771 Query: 128 DVSNAFSPSISKAQPGAPPSSLMGINSYLPSQPSSLPPSYFGNQP---QGIPQPGYN--- 181 + PS SK Q A + + + S PP+ P + IP+P + Sbjct: 772 ATTKPDIPS-SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830 Query: 182 -----PYRHTPGSSRANPYIAPPQLQQCQT---PGPPAHPPPSGPPVQMYQMPPGSLPPV 233 P + G + +P + ++ QT P P A P P G P PPG P Sbjct: 831 ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPT-----PPGPRPTA 885 Query: 234 PSSVQSPAQQQVP 246 +V +P Q P Sbjct: 886 GQTVPTPQQSPKP 898 Score = 32.3 bits (72), Expect = 2.3 Identities = 31/120 (25%), Positives = 44/120 (36%), Gaps = 11/120 (9%) Query: 136 SISKAQPGAPPSSLMGINSYLPSQPSSLPPSYF-GNQPQGIPQPGYNPYRHTPGSS---- 190 S+S+ PPSS++ + L +YF + G +P +P S Sbjct: 2334 SLSETVFDHPPSSVIAL-----PMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPA 2388 Query: 191 RANPYIAPPQLQ-QCQTPGPPAHPPPSGPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARP 249 + P+ L Q P PP PPP PP PP P P P ++ A P Sbjct: 2389 KPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASP 2448 Score = 32.0 bits (71), Expect = 3.0 Identities = 40/142 (28%), Positives = 57/142 (40%), Gaps = 34/142 (23%) Query: 127 QDVSNAFSPSIS------KAQPGAPPSS----LMGINSYLPSQPSSLPPSYFGNQPQGIP 176 Q+ S FS ++ K+QP P + L G + + SQ S+L + QP Sbjct: 899 QEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLIST--AGQPGPHS 956 Query: 177 QPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPSGPPVQMYQMPPGSLP--PVP 234 Q G PG AP + Q P P P GPP Q PP PV Sbjct: 957 QSG-------PG--------APMK----QAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVK 997 Query: 235 SSVQSPAQQQV-PARPGAPSVQ 255 ++PA +++ P AP+V+ Sbjct: 998 KETKAPAAEKLEPKAEQAPTVK 1019 >gi|34304383 Usher syndrome 1G protein [Homo sapiens] Length = 461 Score = 52.8 bits (125), Expect = 2e-06 Identities = 27/83 (32%), Positives = 48/83 (57%), Gaps = 5/83 (6%) Query: 627 EEPKLTLDESYDLVVENKEVLTLQETLEALSLSEYFSTFEKEKIDMESLLMCTVDDLKEM 686 +E L LDE + E L+ L +L + ++ + +EKID+E+L++C+ DL+ + Sbjct: 375 DELDLGLDEDLE-----PETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSI 429 Query: 687 GIPLGPRKKIANFVEHKAAKLKK 709 +PLGPRKKI V + +++ Sbjct: 430 SVPLGPRKKILGAVRRRRQAMER 452 >gi|192807323 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform A [Homo sapiens] Length = 1679 Score = 52.0 bits (123), Expect = 3e-06 Identities = 60/234 (25%), Positives = 92/234 (39%), Gaps = 26/234 (11%) Query: 42 QASASPASLLLPGEDSTDVGEED---SFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQ 98 Q S+ P L G D +G+++ + Q +H Q +Y ++ + P + Q Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAY--KMLARGQPLPDHLQ 201 Query: 99 SPLTTAATSVG-QSGFPK-PLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYL 156 + G Q P P ++ T P A P MG + Sbjct: 202 MAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMP 261 Query: 157 PSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS 216 P PS +PP G P G P+P + P ++ A P P +L Q G P+ PP+ Sbjct: 262 PPGPSGVPPGMPGQPPGGPPKP----WPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA 317 Query: 217 GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQ 270 +PP + P +P QSP Q PA+P AP V + Q++ P+Q Sbjct: 318 --------VPPAASPVMPPQTQSPGQ---PAQP-APMVPLHQK---QSRITPIQ 356 >gi|192807320 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform F [Homo sapiens] Length = 1613 Score = 52.0 bits (123), Expect = 3e-06 Identities = 60/234 (25%), Positives = 92/234 (39%), Gaps = 26/234 (11%) Query: 42 QASASPASLLLPGEDSTDVGEED---SFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQ 98 Q S+ P L G D +G+++ + Q +H Q +Y ++ + P + Q Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAY--KMLARGQPLPDHLQ 201 Query: 99 SPLTTAATSVG-QSGFPK-PLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYL 156 + G Q P P ++ T P A P MG + Sbjct: 202 MAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMP 261 Query: 157 PSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS 216 P PS +PP G P G P+P + P ++ A P P +L Q G P+ PP+ Sbjct: 262 PPGPSGVPPGMPGQPPGGPPKP----WPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA 317 Query: 217 GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQ 270 +PP + P +P QSP Q PA+P AP V + Q++ P+Q Sbjct: 318 --------VPPAASPVMPPQTQSPGQ---PAQP-APMVPLHQK---QSRITPIQ 356 >gi|192807318 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform E [Homo sapiens] Length = 1614 Score = 52.0 bits (123), Expect = 3e-06 Identities = 60/234 (25%), Positives = 92/234 (39%), Gaps = 26/234 (11%) Query: 42 QASASPASLLLPGEDSTDVGEED---SFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQ 98 Q S+ P L G D +G+++ + Q +H Q +Y ++ + P + Q Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAY--KMLARGQPLPDHLQ 201 Query: 99 SPLTTAATSVG-QSGFPK-PLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYL 156 + G Q P P ++ T P A P MG + Sbjct: 202 MAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMP 261 Query: 157 PSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS 216 P PS +PP G P G P+P + P ++ A P P +L Q G P+ PP+ Sbjct: 262 PPGPSGVPPGMPGQPPGGPPKP----WPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA 317 Query: 217 GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQ 270 +PP + P +P QSP Q PA+P AP V + Q++ P+Q Sbjct: 318 --------VPPAASPVMPPQTQSPGQ---PAQP-APMVPLHQK---QSRITPIQ 356 >gi|192807316 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform D [Homo sapiens] Length = 1616 Score = 52.0 bits (123), Expect = 3e-06 Identities = 60/234 (25%), Positives = 92/234 (39%), Gaps = 26/234 (11%) Query: 42 QASASPASLLLPGEDSTDVGEED---SFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQ 98 Q S+ P L G D +G+++ + Q +H Q +Y ++ + P + Q Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAY--KMLARGQPLPDHLQ 201 Query: 99 SPLTTAATSVG-QSGFPK-PLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYL 156 + G Q P P ++ T P A P MG + Sbjct: 202 MAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMP 261 Query: 157 PSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS 216 P PS +PP G P G P+P + P ++ A P P +L Q G P+ PP+ Sbjct: 262 PPGPSGVPPGMPGQPPGGPPKP----WPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA 317 Query: 217 GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQ 270 +PP + P +P QSP Q PA+P AP V + Q++ P+Q Sbjct: 318 --------VPPAASPVMPPQTQSPGQ---PAQP-APMVPLHQK---QSRITPIQ 356 >gi|192807314 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform C [Homo sapiens] Length = 1617 Score = 52.0 bits (123), Expect = 3e-06 Identities = 60/234 (25%), Positives = 92/234 (39%), Gaps = 26/234 (11%) Query: 42 QASASPASLLLPGEDSTDVGEED---SFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQ 98 Q S+ P L G D +G+++ + Q +H Q +Y ++ + P + Q Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAY--KMLARGQPLPDHLQ 201 Query: 99 SPLTTAATSVG-QSGFPK-PLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYL 156 + G Q P P ++ T P A P MG + Sbjct: 202 MAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMP 261 Query: 157 PSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS 216 P PS +PP G P G P+P + P ++ A P P +L Q G P+ PP+ Sbjct: 262 PPGPSGVPPGMPGQPPGGPPKP----WPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA 317 Query: 217 GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQ 270 +PP + P +P QSP Q PA+P AP V + Q++ P+Q Sbjct: 318 --------VPPAASPVMPPQTQSPGQ---PAQP-APMVPLHQK---QSRITPIQ 356 >gi|192807312 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 52.0 bits (123), Expect = 3e-06 Identities = 60/234 (25%), Positives = 92/234 (39%), Gaps = 26/234 (11%) Query: 42 QASASPASLLLPGEDSTDVGEED---SFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQ 98 Q S+ P L G D +G+++ + Q +H Q +Y ++ + P + Q Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAY--KMLARGQPLPDHLQ 201 Query: 99 SPLTTAATSVG-QSGFPK-PLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYL 156 + G Q P P ++ T P A P MG + Sbjct: 202 MAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMP 261 Query: 157 PSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS 216 P PS +PP G P G P+P + P ++ A P P +L Q G P+ PP+ Sbjct: 262 PPGPSGVPPGMPGQPPGGPPKP----WPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA 317 Query: 217 GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQ 270 +PP + P +P QSP Q PA+P AP V + Q++ P+Q Sbjct: 318 --------VPPAASPVMPPQTQSPGQ---PAQP-APMVPLHQK---QSRITPIQ 356 >gi|21071056 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a4 isoform B [Homo sapiens] Length = 1647 Score = 52.0 bits (123), Expect = 3e-06 Identities = 60/234 (25%), Positives = 92/234 (39%), Gaps = 26/234 (11%) Query: 42 QASASPASLLLPGEDSTDVGEED---SFLGQTSIHTSAPQTFSYFSQVSSSSDPFGNIGQ 98 Q S+ P L G D +G+++ + Q +H Q +Y ++ + P + Q Sbjct: 144 QMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQLRAQIMAY--KMLARGQPLPDHLQ 201 Query: 99 SPLTTAATSVG-QSGFPK-PLTALPFTTGSQDVSNAFSPSISKAQPGAPPSSLMGINSYL 156 + G Q P P ++ T P A P MG + Sbjct: 202 MAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGPGPGPAPPNYSRPHGMGGPNMP 261 Query: 157 PSQPSSLPPSYFGNQPQGIPQPGYNPYRHTPGSSRANPYIAPPQLQQCQTPGPPAHPPPS 216 P PS +PP G P G P+P + P ++ A P P +L Q G P+ PP+ Sbjct: 262 PPGPSGVPPGMPGQPPGGPPKP----WPEGPMANAAAPTSTPQKLIPPQPTGRPSPAPPA 317 Query: 217 GPPVQMYQMPPGSLPPVPSSVQSPAQQQVPARPGAPSVQVPSPFLLQNQYEPVQ 270 +PP + P +P QSP Q PA+P AP V + Q++ P+Q Sbjct: 318 --------VPPAASPVMPPQTQSPGQ---PAQP-APMVPLHQK---QSRITPIQ 356 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.133 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,656,320 Number of Sequences: 37866 Number of extensions: 2455759 Number of successful extensions: 19761 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 241 Number of HSP's successfully gapped in prelim test: 1012 Number of HSP's that attempted gapping in prelim test: 11684 Number of HSP's gapped (non-prelim): 5154 length of query: 1000 length of database: 18,247,518 effective HSP length: 112 effective length of query: 888 effective length of database: 14,006,526 effective search space: 12437795088 effective search space used: 12437795088 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.