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Search of human proteins with 5901992
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5901992 keratocan [Homo sapiens]
(352 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5901992 keratocan [Homo sapiens] 720 0.0
gi|41349454 proline arginine-rich end leucine-rich repeat protei... 368 e-102
gi|4506041 proline arginine-rich end leucine-rich repeat protein... 368 e-102
gi|4826876 osteomodulin [Homo sapiens] 257 1e-68
gi|71040111 fibromodulin precursor [Homo sapiens] 255 5e-68
gi|4505047 lumican precursor [Homo sapiens] 236 2e-62
gi|45505137 podocan [Homo sapiens] 145 7e-35
gi|226342933 podocan-like 1 isoform 2 [Homo sapiens] 134 1e-31
gi|226342931 podocan-like 1 isoform 1 [Homo sapiens] 134 1e-31
gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens] 133 3e-31
gi|41350214 asporin [Homo sapiens] 129 4e-30
gi|19743846 decorin isoform a preproprotein [Homo sapiens] 123 3e-28
gi|4503271 decorin isoform a preproprotein [Homo sapiens] 123 3e-28
gi|4502403 biglycan preproprotein [Homo sapiens] 119 4e-27
gi|34577057 fibronectin leucine rich transmembrane protein 1 [Ho... 113 3e-25
gi|226342935 podocan-like 1 isoform 3 [Homo sapiens] 106 3e-23
gi|38202222 fibronectin leucine rich transmembrane protein 3 pre... 104 1e-22
gi|7019383 fibronectin leucine rich transmembrane protein 3 prec... 104 1e-22
gi|7019381 fibronectin leucine rich transmembrane protein 2 [Hom... 103 2e-22
gi|20302168 toll-like receptor 8 [Homo sapiens] 99 6e-21
gi|157694513 leucine-rich repeat-containing G protein-coupled re... 99 7e-21
gi|4504379 leucine-rich repeat-containing G protein-coupled rece... 93 3e-19
gi|122937309 leucine rich repeat containing 4B [Homo sapiens] 93 4e-19
gi|153251229 chondroadherin precursor [Homo sapiens] 93 4e-19
gi|51317373 netrin-G1 ligand [Homo sapiens] 92 5e-19
gi|198041768 synleurin [Homo sapiens] 92 9e-19
gi|205277468 leucine rich repeat containing 15 isoform a [Homo s... 91 2e-18
gi|18677767 leucine rich repeat containing 15 isoform b [Homo sa... 91 2e-18
gi|194440719 chondroadherin-like [Homo sapiens] 89 5e-18
gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo sa... 87 3e-17
>gi|5901992 keratocan [Homo sapiens]
Length = 352
Score = 720 bits (1859), Expect = 0.0
Identities = 352/352 (100%), Positives = 352/352 (100%)
Query: 1 MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHDFECPMECFCPPSFPTALYCEN 60
MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHDFECPMECFCPPSFPTALYCEN
Sbjct: 1 MAGTICFIMWVLFITDTVWSRSVRQVYEVHDSDDWTIHDFECPMECFCPPSFPTALYCEN 60
Query: 61 RGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQL 120
RGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQL
Sbjct: 61 RGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQL 120
Query: 121 KKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVD 180
KKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVD
Sbjct: 121 KKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVD 180
Query: 181 NAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVA 240
NAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVA
Sbjct: 181 NAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVA 240
Query: 241 FLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVS 300
FLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVS
Sbjct: 241 FLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLHLDHNKIKSVNVS 300
Query: 301 VICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQAVII 352
VICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQAVII
Sbjct: 301 VICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQAVII 352
>gi|41349454 proline arginine-rich end leucine-rich repeat protein
precursor [Homo sapiens]
Length = 382
Score = 368 bits (945), Expect = e-102
Identities = 177/313 (56%), Positives = 235/313 (75%), Gaps = 3/313 (0%)
Query: 41 ECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
+CP EC+CPP FP+ALYC++R L+++P IP RI YLYLQNN I +P + F+NAT LRWI
Sbjct: 72 DCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWI 131
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
NL+ N+I I++ L +L L+FL++E N+LEEVPS LPR+LEQL+L++N +SRIP G
Sbjct: 132 NLDNNRIRK--IDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPG 189
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
FS LENL LLDLQ+N+L D F+ DTF GLKNLMQLN+A N LR MPPR+P QL+L
Sbjct: 190 VFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYL 249
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280
D+N IE IP YF P +AF+RLN+NKL+D GLP F++S++L L LSHN+++ VP I
Sbjct: 250 DSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAI 309
Query: 281 SAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDS-FSYGPHLRYLRLDGNEIKPPIPMA 339
+ L+HL+L++N I+ +N + ICP+ + + S PHLRYLRLDGN +KPPIP+
Sbjct: 310 NNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLD 369
Query: 340 LMTCFRLLQAVII 352
LM CFRLLQ+V+I
Sbjct: 370 LMMCFRLLQSVVI 382
>gi|4506041 proline arginine-rich end leucine-rich repeat protein
precursor [Homo sapiens]
Length = 382
Score = 368 bits (945), Expect = e-102
Identities = 177/313 (56%), Positives = 235/313 (75%), Gaps = 3/313 (0%)
Query: 41 ECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
+CP EC+CPP FP+ALYC++R L+++P IP RI YLYLQNN I +P + F+NAT LRWI
Sbjct: 72 DCPRECYCPPDFPSALYCDSRNLRKVPVIPPRIHYLYLQNNFITELPVESFQNATGLRWI 131
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
NL+ N+I I++ L +L L+FL++E N+LEEVPS LPR+LEQL+L++N +SRIP G
Sbjct: 132 NLDNNRIRK--IDQRVLEKLPGLVFLYMEKNQLEEVPSALPRNLEQLRLSQNHISRIPPG 189
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
FS LENL LLDLQ+N+L D F+ DTF GLKNLMQLN+A N LR MPPR+P QL+L
Sbjct: 190 VFSKLENLLLLDLQHNRLSDGVFKPDTFHGLKNLMQLNLAHNILRKMPPRVPTAIHQLYL 249
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280
D+N IE IP YF P +AF+RLN+NKL+D GLP F++S++L L LSHN+++ VP I
Sbjct: 250 DSNKIETIPNGYFKSFPNLAFIRLNYNKLTDRGLPKNSFNISNLLVLHLSHNRISSVPAI 309
Query: 281 SAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDS-FSYGPHLRYLRLDGNEIKPPIPMA 339
+ L+HL+L++N I+ +N + ICP+ + + S PHLRYLRLDGN +KPPIP+
Sbjct: 310 NNRLEHLYLNNNSIEKINGTQICPNDLVAFHDFSSDLENVPHLRYLRLDGNYLKPPIPLD 369
Query: 340 LMTCFRLLQAVII 352
LM CFRLLQ+V+I
Sbjct: 370 LMMCFRLLQSVVI 382
>gi|4826876 osteomodulin [Homo sapiens]
Length = 421
Score = 257 bits (657), Expect = 1e-68
Identities = 135/303 (44%), Positives = 193/303 (63%), Gaps = 10/303 (3%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWIN 101
C ECFCP +FP+++YC+NR LK IP IP I LYLQ N IE + F NAT L+ IN
Sbjct: 62 CVSECFCPTNFPSSMYCDNRKLKTIPNIPMHIQQLYLQFNEIEAVTANSFINATHLKEIN 121
Query: 102 LNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGT 161
L+ NKI + I+ G ++L LL L LE N LEE P PLP+SLE+L L N++S++
Sbjct: 122 LSHNKIKSQKIDYGVFAKLPNLLQLHLEHNNLEEFPFPLPKSLERLLLGYNEISKLQTNA 181
Query: 162 FSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLD 221
L NLT+LDL N L D+ + F ++ LMQLN+ N L +MPP LP++ M L L+
Sbjct: 182 MDGLVNLTMLDLCYNYLHDSLLKDKIFAKMEKLMQLNLCSNRLESMPPGLPSSLMYLSLE 241
Query: 222 NNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRIS 281
NNSI IPE YF+ +PK+ LR++HNKL D +P F++ +I++L + HN+L + I
Sbjct: 242 NNSISSIPEKYFDKLPKLHTLRMSHNKLQD--IPYNIFNLPNIVELSVGHNKLKQAFYIP 299
Query: 282 AHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALM 341
+L+HL+L +N+I+ +N++V+CPS L + HL Y+R+D N++K PI +
Sbjct: 300 RNLEHLYLQNNEIEKMNLTVMCPSIDPL--------HYHHLTYIRVDQNKLKEPISSYIF 351
Query: 342 TCF 344
CF
Sbjct: 352 FCF 354
>gi|71040111 fibromodulin precursor [Homo sapiens]
Length = 376
Score = 255 bits (651), Expect = 5e-68
Identities = 131/313 (41%), Positives = 204/313 (65%), Gaps = 12/313 (3%)
Query: 41 ECPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
+CP EC CPP+FPTA+YC+NR LK +P +PSR+ Y+Y QNN I +I E F+NAT L WI
Sbjct: 75 DCPQECDCPPNFPTAMYCDNRNLKYLPFVPSRMKYVYFQNNQITSIQEGVFDNATGLLWI 134
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
L+ N+IT+ + + S+L+ L L+L+ N L +P PLPRSL +L L N++SR+P
Sbjct: 135 ALHGNQITSDKVGRKVFSKLRHLERLYLDHNNLTRMPGPLPRSLRELHLDHNQISRVPNN 194
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
LENLT L LQ+N++ + + +GL++L+ L+++ N LR +P LP+ QL++
Sbjct: 195 ALEGLENLTALYLQHNEIQEVG---SSMRGLRSLILLDLSYNHLRKVPDGLPSALEQLYM 251
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280
++N++ +P++YF PK+ ++RL+HN L++ GL S F+ SS+L+L LS+NQL K+P +
Sbjct: 252 EHNNVYTVPDSYFRGAPKLLYVRLSHNSLTNNGLASNTFNSSSLLELDLSYNQLQKIPPV 311
Query: 281 SAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIK-PPIPMA 339
+ +L++L+L N+I ++S C ++ +FS L+ LRLDGNEIK +P
Sbjct: 312 NTNLENLYLQGNRINEFSISSFCTVVDVV-----NFS---KLQVLRLDGNEIKRSAMPAD 363
Query: 340 LMTCFRLLQAVII 352
C RL + I
Sbjct: 364 APLCLRLASLIEI 376
>gi|4505047 lumican precursor [Homo sapiens]
Length = 338
Score = 236 bits (602), Expect = 2e-62
Identities = 123/312 (39%), Positives = 194/312 (62%), Gaps = 12/312 (3%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWIN 101
C EC CP S+P+A+YC+ LK +P +P I YLYL+NN I+ I EK FEN T L+W+
Sbjct: 37 CAPECNCPESYPSAMYCDELKLKSVPMVPPGIKYLYLRNNQIDHIDEKAFENVTDLQWLI 96
Query: 102 LNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGT 161
L+ N + N I+ S+LK+L L + N L E PLP+SLE LQL NK++++ G+
Sbjct: 97 LDHNLLENSKIKGRVFSKLKQLKKLHINHNNLTESVGPLPKSLEDLQLTHNKITKL--GS 154
Query: 162 FSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLD 221
F L NLT + LQ+N+L ++A FKGLK+L L+++ N + +P LP + + L+LD
Sbjct: 155 FEGLVNLTFIHLQHNRLKEDAVSA-AFKGLKSLEYLDLSFNQIARLPSGLPVSLLTLYLD 213
Query: 222 NNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRIS 281
NN I IP+ YF + +LRL+HN+L+D G+P F+VSS+++L LS+N+L +P ++
Sbjct: 214 NNKISNIPDEYFKRFNALQYLRLSHNELADSGIPGNSFNVSSLVELDLSYNKLKNIPTVN 273
Query: 282 AHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEI-KPPIPMAL 340
+L++ +L+ N+++ ++ C L S+S +++LRLDGN I + +P +
Sbjct: 274 ENLENYYLEVNQLEKFDIKSFCKILGPL-----SYS---KIKHLRLDGNRISETSLPPDM 325
Query: 341 MTCFRLLQAVII 352
C R+ V +
Sbjct: 326 YECLRVANEVTL 337
>gi|45505137 podocan [Homo sapiens]
Length = 661
Score = 145 bits (365), Expect = 7e-35
Identities = 99/295 (33%), Positives = 150/295 (50%), Gaps = 19/295 (6%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP +C C S + C L+E P +P +L LQNN +E I + +L +
Sbjct: 116 CPRDCAC--SQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETL 173
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
NL N++T+ G+ + A L L +L+L +N+L P LP +L + A N +++I
Sbjct: 174 NLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGL 233
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
TF NL + L NNKL D + F G N+ L ++ N LR++P LP +L L
Sbjct: 234 TFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHL 293
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHNQLTKVPR 279
NN +E IP F+ + + L L +N L+DEGL + F +SS+ L LS N L++VP
Sbjct: 294 KNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPA 353
Query: 280 -ISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIK 333
+ L LHL+ N I+SV+ +V+ P S L YL L N+++
Sbjct: 354 GLPRSLVLLHLEKNAIRSVDANVLTPIRS--------------LEYLLLHSNQLR 394
Score = 112 bits (280), Expect = 5e-25
Identities = 71/252 (28%), Positives = 128/252 (50%), Gaps = 3/252 (1%)
Query: 60 NRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALS 118
+ L +PA +P + L+L+ N I ++ L ++ L+ N++ GI A
Sbjct: 345 SNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQ 404
Query: 119 QLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKL 178
LK+L + L +N LE VPS LPR + L + N+++ I + F+ L L+L N++
Sbjct: 405 GLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRI 464
Query: 179 VDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPK 238
RD F+ L+ L L+++ N L +PP LP N L + N + + + +
Sbjct: 465 TSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQ 524
Query: 239 VAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHNQLTKVPR-ISAHLQHLHLDHNKIKS 296
+ L L N+L L R + D++ + L ++ NQLT++P + L++L+L +NKI +
Sbjct: 525 LRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISA 584
Query: 297 VNVSVICPSPSM 308
V + +P++
Sbjct: 585 VPANAFDSTPNL 596
Score = 110 bits (276), Expect = 1e-24
Identities = 86/304 (28%), Positives = 132/304 (43%), Gaps = 39/304 (12%)
Query: 56 LYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEK 114
LY N L P +P+ + + N + I F LR + L+ NK+ + G+
Sbjct: 199 LYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPD 258
Query: 115 GALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
+ + L L N L VP LP +L +L L NK+ +IP G FS L +L L LQ
Sbjct: 259 NMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQ 318
Query: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFN 234
NN L D +TF L +L L+++ N L +P LP + + L L+ N+I + N
Sbjct: 319 NNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLT 378
Query: 235 VIPKVAFLRLNHNKLSDEGLPSRGFD----------------------VSSILDLQLSHN 272
I + +L L+ N+L ++G+ F + L + HN
Sbjct: 379 PIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHN 438
Query: 273 QLTKVPR----ISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLD 328
Q+T + R + L+ L+L +N+I S V RD+F LR L L
Sbjct: 439 QITGIGREDFATTYFLEELNLSYNRITSPQV------------HRDAFRKLRLLRSLDLS 486
Query: 329 GNEI 332
GN +
Sbjct: 487 GNRL 490
Score = 96.3 bits (238), Expect = 4e-20
Identities = 59/192 (30%), Positives = 100/192 (52%), Gaps = 1/192 (0%)
Query: 60 NRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALS 118
N L+ +P+ +P R+ L + +N I I + F L +NL+ N+IT+ + + A
Sbjct: 416 NNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFR 475
Query: 119 QLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKL 178
+L+ L L L N L +P LPR++ L++ RN+++ + +G + L L L +N+L
Sbjct: 476 KLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRL 535
Query: 179 VDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPK 238
A + L +L L++A N L +P LP + L+L NN I +P N F+ P
Sbjct: 536 RSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPN 595
Query: 239 VAFLRLNHNKLS 250
+ + L NKL+
Sbjct: 596 LKGIFLRFNKLA 607
Score = 69.3 bits (168), Expect = 5e-12
Identities = 41/136 (30%), Positives = 65/136 (47%)
Query: 67 PAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFL 126
P +P + L ++ N + + QLR + L N++ + + A L L L
Sbjct: 495 PGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLL 554
Query: 127 FLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRD 186
+ N+L E+P LP SLE L L NK+S +P F + NL + L+ NKL +
Sbjct: 555 DIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDS 614
Query: 187 TFKGLKNLMQLNMAKN 202
F+ LK+L L++ N
Sbjct: 615 AFRRLKHLQVLDIEGN 630
>gi|226342933 podocan-like 1 isoform 2 [Homo sapiens]
Length = 510
Score = 134 bits (337), Expect = 1e-31
Identities = 89/262 (33%), Positives = 132/262 (50%), Gaps = 5/262 (1%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP+ C CP + C+ L+ P I +L LQNN ++ +P + LR +
Sbjct: 44 CPLRCSCPRV--DTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 101
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
NL+ N I++ G+ A L +L L + N+L P LPRSL LA N+V I
Sbjct: 102 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPL 161
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
TF L + L NN+L + D F+G + + L+++ N L +PP LP + +L L
Sbjct: 162 TFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHL 221
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFD-VSSILDLQLSHNQLTKVPR 279
NN I +P + ++ L L HN+L+D GL + F + S+ L LSHNQLT VP
Sbjct: 222 QNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 281
Query: 280 -ISAHLQHLHLDHNKIKSVNVS 300
+ L LHL N+I+ V +
Sbjct: 282 GLPRTLAILHLGRNRIRQVEAA 303
Score = 116 bits (291), Expect = 3e-26
Identities = 71/231 (30%), Positives = 118/231 (51%), Gaps = 2/231 (0%)
Query: 67 PAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFL 126
P++P + L+LQNNLI +P TQLR + L N++T+ G++ S+L L +L
Sbjct: 210 PSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 269
Query: 127 FLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRD 186
L N+L VP+ LPR+L L L RN++ ++ L L LQ+N+L +
Sbjct: 270 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 329
Query: 187 TFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNH 246
+ L+ L L++ N L +PP LP L L +N + + P + L L +
Sbjct: 330 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 389
Query: 247 NKLSDEGLPSRGF-DVSSILDLQLSHNQLTKVPR-ISAHLQHLHLDHNKIK 295
N+L+ + R F + ++ L L+ NQLT++P + L+ L L N+++
Sbjct: 390 NRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLR 440
Score = 108 bits (269), Expect = 9e-24
Identities = 83/283 (29%), Positives = 130/283 (45%), Gaps = 16/283 (5%)
Query: 80 NNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSP 139
N ++E P F LR + L+ N+++N G+ A + + L L +N+L +P
Sbjct: 153 NQVMEIFP-LTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPS 211
Query: 140 LPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNM 199
LP SLE+L L N +S++P+G S L L LQ+N+L D+ TF L +L L++
Sbjct: 212 LPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDL 271
Query: 200 AKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF 259
+ N L +P LP L L N I + + + +L L HN+L GLP+
Sbjct: 272 SHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGAL 331
Query: 260 -DVSSILDLQLSHNQLTKV-PRISAHLQHLHLDHNKIKSVNVSVICPSPSMLP------- 310
+ + L L N L +V P + L+ L L HN + ++ + +P +
Sbjct: 332 RPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNR 391
Query: 311 -----AERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQ 348
+F LR L L GN++ +PM L T R LQ
Sbjct: 392 LASARVHHRAFRRLRALRSLDLAGNQL-TRLPMGLPTGLRTLQ 433
Score = 79.7 bits (195), Expect = 4e-15
Identities = 57/188 (30%), Positives = 85/188 (45%), Gaps = 1/188 (0%)
Query: 63 LKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLK 121
L +PA +P + L+L N I + A LR++ L N++ + G+ GAL L+
Sbjct: 276 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 335
Query: 122 KLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDN 181
L L L N L+ VP LPR L L L N V+ + LT L+L N+L
Sbjct: 336 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 395
Query: 182 AFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAF 241
F+ L+ L L++A N L +P LP L L N + + + ++
Sbjct: 396 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 455
Query: 242 LRLNHNKL 249
L L HN+L
Sbjct: 456 LSLAHNRL 463
>gi|226342931 podocan-like 1 isoform 1 [Homo sapiens]
Length = 512
Score = 134 bits (337), Expect = 1e-31
Identities = 89/262 (33%), Positives = 132/262 (50%), Gaps = 5/262 (1%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP+ C CP + C+ L+ P I +L LQNN ++ +P + LR +
Sbjct: 46 CPLRCSCPRV--DTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 103
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
NL+ N I++ G+ A L +L L + N+L P LPRSL LA N+V I
Sbjct: 104 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPL 163
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
TF L + L NN+L + D F+G + + L+++ N L +PP LP + +L L
Sbjct: 164 TFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHL 223
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFD-VSSILDLQLSHNQLTKVPR 279
NN I +P + ++ L L HN+L+D GL + F + S+ L LSHNQLT VP
Sbjct: 224 QNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 283
Query: 280 -ISAHLQHLHLDHNKIKSVNVS 300
+ L LHL N+I+ V +
Sbjct: 284 GLPRTLAILHLGRNRIRQVEAA 305
Score = 116 bits (291), Expect = 3e-26
Identities = 71/231 (30%), Positives = 118/231 (51%), Gaps = 2/231 (0%)
Query: 67 PAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFL 126
P++P + L+LQNNLI +P TQLR + L N++T+ G++ S+L L +L
Sbjct: 212 PSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYL 271
Query: 127 FLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRD 186
L N+L VP+ LPR+L L L RN++ ++ L L LQ+N+L +
Sbjct: 272 DLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAG 331
Query: 187 TFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNH 246
+ L+ L L++ N L +PP LP L L +N + + P + L L +
Sbjct: 332 ALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAY 391
Query: 247 NKLSDEGLPSRGF-DVSSILDLQLSHNQLTKVPR-ISAHLQHLHLDHNKIK 295
N+L+ + R F + ++ L L+ NQLT++P + L+ L L N+++
Sbjct: 392 NRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLR 442
Score = 108 bits (269), Expect = 9e-24
Identities = 83/283 (29%), Positives = 130/283 (45%), Gaps = 16/283 (5%)
Query: 80 NNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSP 139
N ++E P F LR + L+ N+++N G+ A + + L L +N+L +P
Sbjct: 155 NQVMEIFP-LTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPS 213
Query: 140 LPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNM 199
LP SLE+L L N +S++P+G S L L LQ+N+L D+ TF L +L L++
Sbjct: 214 LPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDL 273
Query: 200 AKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF 259
+ N L +P LP L L N I + + + +L L HN+L GLP+
Sbjct: 274 SHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGAL 333
Query: 260 -DVSSILDLQLSHNQLTKV-PRISAHLQHLHLDHNKIKSVNVSVICPSPSMLP------- 310
+ + L L N L +V P + L+ L L HN + ++ + +P +
Sbjct: 334 RPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNR 393
Query: 311 -----AERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRLLQ 348
+F LR L L GN++ +PM L T R LQ
Sbjct: 394 LASARVHHRAFRRLRALRSLDLAGNQL-TRLPMGLPTGLRTLQ 435
Score = 79.7 bits (195), Expect = 4e-15
Identities = 57/188 (30%), Positives = 85/188 (45%), Gaps = 1/188 (0%)
Query: 63 LKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLK 121
L +PA +P + L+L N I + A LR++ L N++ + G+ GAL L+
Sbjct: 278 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 337
Query: 122 KLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDN 181
L L L N L+ VP LPR L L L N V+ + LT L+L N+L
Sbjct: 338 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 397
Query: 182 AFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAF 241
F+ L+ L L++A N L +P LP L L N + + + ++
Sbjct: 398 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 457
Query: 242 LRLNHNKL 249
L L HN+L
Sbjct: 458 LSLAHNRL 465
>gi|4557543 extracellular matrix protein 2 precursor [Homo sapiens]
Length = 699
Score = 133 bits (334), Expect = 3e-31
Identities = 87/253 (34%), Positives = 139/253 (54%), Gaps = 4/253 (1%)
Query: 48 CPPSFPTALYCENRGLKEIPAIPS-RIWYLYLQNNLIETIPEKPFENATQLRWINLNKNK 106
C S+ T + C N L +IP + + +I L L N I +IP++ F L ++L+KN
Sbjct: 320 CSLSYRT-ISCINAMLTQIPPLTAPQITSLELTGNSIASIPDEAFNGLPNLERLDLSKNN 378
Query: 107 ITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLE 166
IT+ GI A LKKL+ L ++ N L ++PS LP +LE+L++ N + I + + S+L
Sbjct: 379 ITSSGIGPKAFKLLKKLMRLNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLN 438
Query: 167 NLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIE 226
L L+L+ N L + FK LK+L L + KN R +P LP + +L+L+NN IE
Sbjct: 439 QLVTLELEGNNLSEANVNPLAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIE 498
Query: 227 GIPENYFNVIPKVAFLRLNHNKLSDEGL-PSRGFDVSSILDLQLSHNQLTKVPR-ISAHL 284
I E FN K+ + L +NK+ + + P + ++ + LS+N+L VP + L
Sbjct: 499 EITEICFNHTRKINVIVLRYNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSL 558
Query: 285 QHLHLDHNKIKSV 297
HL L N+I+ +
Sbjct: 559 LHLVLLGNQIERI 571
Score = 122 bits (305), Expect = 6e-28
Identities = 88/305 (28%), Positives = 154/305 (50%), Gaps = 17/305 (5%)
Query: 56 LYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEK 114
L + L +IP+ +PS + L + N ++ I E+ + QL + L N ++ +
Sbjct: 398 LNMDGNNLIQIPSQLPSTLEELKVNENNLQAIDEESLSDLNQLVTLELEGNNLSEANVNP 457
Query: 115 GALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
A LK L +L L N+ +P LP S+E+L L N++ I + F++ + ++ L+
Sbjct: 458 LAFKPLKSLAYLRLGKNKFRIIPQGLPGSIEELYLENNQIEEITEICFNHTRKINVIVLR 517
Query: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYF- 233
NK+ +N + +NL ++++ N L ++P LP + + L L N IE IP F
Sbjct: 518 YNKIEENRIAPLAWINQENLESIDLSYNKLYHVPSYLPKSLLHLVLLGNQIERIPGYVFG 577
Query: 234 NVIPKVAFLRLNHNKLSDEGLPSRGF--DVSSILDLQLSHNQLTKVPRISAHLQHLH--- 288
++ P + +L L+ NKL+D+G+ F S+ +L L HN L +P ++ LH
Sbjct: 578 HMEPGLEYLYLSFNKLADDGMDRVSFYGAYHSLRELFLDHNDLKSIPPGIQEMKALHFLR 637
Query: 289 LDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEIK-PPIPMALMTCFRLL 347
L++NKI+++ IC AE D S +L +L L+ N IK IP +C R
Sbjct: 638 LNNNKIRNILPEEIC------NAEEDDDS---NLEHLHLENNYIKIREIPSYTFSCIRSY 688
Query: 348 QAVII 352
++++
Sbjct: 689 SSIVL 693
>gi|41350214 asporin [Homo sapiens]
Length = 380
Score = 129 bits (324), Expect = 4e-30
Identities = 86/268 (32%), Positives = 138/268 (51%), Gaps = 11/268 (4%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C + ++C + GL +P IP L LQNN I+ I E F+ T L +
Sbjct: 75 CPFGCQC---YSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKENDFKGLTSLYGL 131
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
LN NK+T I A KKL L+L N+L E+P LP+SL +L++ NKV +I +
Sbjct: 132 ILNNNKLTK--IHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHENKVKKIQKD 189
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
TF + L +L++ N L +N + F+G+ + + +A+ L ++P LP ++L L
Sbjct: 190 TFKGMNALHVLEMSANPLDNNGIEPGAFEGV-TVFHIRIAEAKLTSVPKGLPPTLLELHL 248
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280
D N I + F ++ L L +NK++D S ++ + ++ L +N+L K+P
Sbjct: 249 DYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLA-NIPRVREIHLENNKLKKIPSG 307
Query: 281 SAHLQHLH---LDHNKIKSVNVSVICPS 305
L++L L N I V V+ CP+
Sbjct: 308 LPELKYLQIIFLHSNSIARVGVNDFCPT 335
>gi|19743846 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 123 bits (308), Expect = 3e-28
Identities = 80/269 (29%), Positives = 140/269 (52%), Gaps = 14/269 (5%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C + C + GL ++P +P L LQNN I I + F+N L +
Sbjct: 54 CPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
L NKI+ + GA + L KL L+L N+L+E+P +P++L++L+ N+++++ +
Sbjct: 111 ILVNNKISK--VSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKV 168
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
TF+ L + +++L N L + + F+G+K L + +A + ++P LP + +L L
Sbjct: 169 TFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHL 228
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLS--DEGLPSRGFDVSSILDLQLSHNQLTKVP 278
D N I + + +A L L+ N +S D G + + + +L L +N+LT+VP
Sbjct: 229 DGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLA---NTPHLRELHLDNNKLTRVP 285
Query: 279 RISA---HLQHLHLDHNKIKSVNVSVICP 304
A ++Q ++L +N I V S CP
Sbjct: 286 GGLAEHKYIQVVYLHNNNISVVGSSDFCP 314
Score = 92.4 bits (228), Expect = 5e-19
Identities = 62/215 (28%), Positives = 103/215 (47%), Gaps = 14/215 (6%)
Query: 130 DNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFK 189
D L++VP LP L L NK++ I G F NL+NL L L NNK+ + F
Sbjct: 69 DLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKI--SKVSPGAFT 126
Query: 190 GLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKL 249
L L +L ++KN L+ +P ++P +L N I + + FN + ++ + L N L
Sbjct: 127 PLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPL 186
Query: 250 SDEGLPSRGFD-VSSILDLQLSHNQLTKVPR-ISAHLQHLHLDHNKIKSVNVSVI----- 302
G+ + F + + ++++ +T +P+ + L LHLD NKI V+ + +
Sbjct: 187 KSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNN 246
Query: 303 -----CPSPSMLPAERDSFSYGPHLRYLRLDGNEI 332
S+ + S + PHLR L LD N++
Sbjct: 247 LAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 281
>gi|4503271 decorin isoform a preproprotein [Homo sapiens]
Length = 359
Score = 123 bits (308), Expect = 3e-28
Identities = 80/269 (29%), Positives = 140/269 (52%), Gaps = 14/269 (5%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C + C + GL ++P +P L LQNN I I + F+N L +
Sbjct: 54 CPFRCQC---HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHAL 110
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
L NKI+ + GA + L KL L+L N+L+E+P +P++L++L+ N+++++ +
Sbjct: 111 ILVNNKISK--VSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKV 168
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
TF+ L + +++L N L + + F+G+K L + +A + ++P LP + +L L
Sbjct: 169 TFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHL 228
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLS--DEGLPSRGFDVSSILDLQLSHNQLTKVP 278
D N I + + +A L L+ N +S D G + + + +L L +N+LT+VP
Sbjct: 229 DGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLA---NTPHLRELHLDNNKLTRVP 285
Query: 279 RISA---HLQHLHLDHNKIKSVNVSVICP 304
A ++Q ++L +N I V S CP
Sbjct: 286 GGLAEHKYIQVVYLHNNNISVVGSSDFCP 314
Score = 92.4 bits (228), Expect = 5e-19
Identities = 62/215 (28%), Positives = 103/215 (47%), Gaps = 14/215 (6%)
Query: 130 DNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFK 189
D L++VP LP L L NK++ I G F NL+NL L L NNK+ + F
Sbjct: 69 DLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKI--SKVSPGAFT 126
Query: 190 GLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKL 249
L L +L ++KN L+ +P ++P +L N I + + FN + ++ + L N L
Sbjct: 127 PLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIELGTNPL 186
Query: 250 SDEGLPSRGFD-VSSILDLQLSHNQLTKVPR-ISAHLQHLHLDHNKIKSVNVSVI----- 302
G+ + F + + ++++ +T +P+ + L LHLD NKI V+ + +
Sbjct: 187 KSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAASLKGLNN 246
Query: 303 -----CPSPSMLPAERDSFSYGPHLRYLRLDGNEI 332
S+ + S + PHLR L LD N++
Sbjct: 247 LAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKL 281
>gi|4502403 biglycan preproprotein [Homo sapiens]
Length = 368
Score = 119 bits (298), Expect = 4e-27
Identities = 86/267 (32%), Positives = 134/267 (50%), Gaps = 11/267 (4%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C + C + GLK +P I L LQNN I + + F+ L +
Sbjct: 63 CPFGCHC---HLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYAL 119
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
L NKI+ I + A S L+KL L++ N L E+P LP SL +L++ N++ ++P+G
Sbjct: 120 VLVNNKISK--IHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKG 177
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
FS L N+ +++ N L ++ F+ F GLK L L +++ L +P LP +L L
Sbjct: 178 VFSGLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHL 236
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRI 280
D+N I+ I K+ L L HN++ S F + ++ +L L +N+L +VP
Sbjct: 237 DHNKIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSF-LPTLRELHLDNNKLARVPSG 295
Query: 281 SAH---LQHLHLDHNKIKSVNVSVICP 304
LQ ++L N I V V+ CP
Sbjct: 296 LPDLKLLQVVYLHSNNITKVGVNDFCP 322
>gi|34577057 fibronectin leucine rich transmembrane protein 1 [Homo
sapiens]
Length = 674
Score = 113 bits (282), Expect = 3e-25
Identities = 87/280 (31%), Positives = 126/280 (45%), Gaps = 54/280 (19%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLI----------------- 83
CP C C F +YC +RGL IPA IP LYLQNN I
Sbjct: 54 CPSVCRCDNGF---IYCNDRGLTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKVNVQV 110
Query: 84 -----------------------------ETIPEKPFENATQLRWINLNKNKITNYGIEK 114
TI L ++L+ N ++ IE+
Sbjct: 111 IYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSIEE 170
Query: 115 GALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
A + K+L LFL N L +PS LP +LE+L+L N++S IP F L +L L L
Sbjct: 171 DAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTIPLHAFKGLNSLRRLVLD 230
Query: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLP-ANTMQLFLDNNSIEGIPENYF 233
N L + DTF L+NL +L++ +N+L P LP A+ +L+L +N+I IP N
Sbjct: 231 GNLLANQRIADDTFSRLQNLTELSLVRNSLAAPPLNLPSAHLQKLYLQDNAISHIPYNTL 290
Query: 234 NVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHN 272
+ ++ L L++N L+ LP F D+ ++ L L +N
Sbjct: 291 AKMRELERLDLSNNNLTT--LPRGLFDDLGNLAQLLLRNN 328
Score = 54.7 bits (130), Expect = 1e-07
Identities = 45/175 (25%), Positives = 76/175 (43%), Gaps = 27/175 (15%)
Query: 125 FLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQ 184
F++ D L +P+ +P ++ T L LQNN+ ++NA
Sbjct: 64 FIYCNDRGLTSIPADIP------------------------DDATTLYLQNNQ-INNAGI 98
Query: 185 RDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRL 244
K N+ + + +N L P LP + +L L +N++ I + IP + L L
Sbjct: 99 PQDLKTKVNVQVIYLYENDLDEFPINLPRSLRELHLQDNNVRTIARDSLARIPLLEKLHL 158
Query: 245 NHNKLSDEGLPSRGF-DVSSILDLQLSHNQLTKVPRISAH-LQHLHLDHNKIKSV 297
+ N +S + F D + L LS N L+ +P H L+ L LD N+I ++
Sbjct: 159 DDNSVSTVSIEEDAFADSKQLKLLFLSRNHLSSIPSGLPHTLEELRLDDNRISTI 213
Score = 38.1 bits (87), Expect = 0.012
Identities = 40/145 (27%), Positives = 63/145 (43%), Gaps = 28/145 (19%)
Query: 204 LRNMPPRLPANTMQLFLDNNSIE--GIPENYFNVIPKVAFLRLNHNKLSDE--GLPSRGF 259
L ++P +P + L+L NN I GIP++ + V + L N L + LP
Sbjct: 72 LTSIPADIPDDATTLYLQNNQINNAGIPQDLKTKV-NVQVIYLYENDLDEFPINLPR--- 127
Query: 260 DVSSILDLQLSHNQLTKVPRISAH----LQHLHLDHNKIKSVNVSVICPSPSMLPAERDS 315
S+ +L L N + + R S L+ LHLD N + +V++ E D+
Sbjct: 128 ---SLRELHLQDNNVRTIARDSLARIPLLEKLHLDDNSVSTVSI------------EEDA 172
Query: 316 FSYGPHLRYLRLDGNEIKPPIPMAL 340
F+ L+ L L N + IP L
Sbjct: 173 FADSKQLKLLFLSRNHLS-SIPSGL 196
>gi|226342935 podocan-like 1 isoform 3 [Homo sapiens]
Length = 421
Score = 106 bits (265), Expect = 3e-23
Identities = 66/219 (30%), Positives = 110/219 (50%), Gaps = 2/219 (0%)
Query: 79 QNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPS 138
+NNLI +P TQLR + L N++T+ G++ S+L L +L L N+L VP+
Sbjct: 133 KNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPA 192
Query: 139 PLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLN 198
LPR+L L L RN++ ++ L L LQ+N+L + + L+ L L+
Sbjct: 193 GLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLH 252
Query: 199 MAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRG 258
+ N L +PP LP L L +N + + P + L L +N+L+ + R
Sbjct: 253 LYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRA 312
Query: 259 F-DVSSILDLQLSHNQLTKVPR-ISAHLQHLHLDHNKIK 295
F + ++ L L+ NQLT++P + L+ L L N+++
Sbjct: 313 FRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLR 351
Score = 103 bits (256), Expect = 3e-22
Identities = 87/322 (27%), Positives = 137/322 (42%), Gaps = 36/322 (11%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP+ C CP + C+ L+ P I +L LQNN ++ +P + LR +
Sbjct: 44 CPLRCSCPRV--DTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTL 101
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
NL+ N I++ G+ A L +L L + N+ N +S++P+G
Sbjct: 102 NLHNNLISSEGLPDEAFESLTQLQHLCVAHNK------------------NNLISKVPRG 143
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
S L L LQ+N+L D+ TF L +L L+++ N L +P LP L L
Sbjct: 144 ALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHL 203
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHNQLTKV-P 278
N I + + + +L L HN+L GLP+ + + L L N L +V P
Sbjct: 204 GRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPP 263
Query: 279 RISAHLQHLHLDHNKIKSVNVSVICPSPSMLP------------AERDSFSYGPHLRYLR 326
+ L+ L L HN + ++ + +P + +F LR L
Sbjct: 264 ALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLD 323
Query: 327 LDGNEIKPPIPMALMTCFRLLQ 348
L GN++ +PM L T R LQ
Sbjct: 324 LAGNQL-TRLPMGLPTGLRTLQ 344
Score = 79.7 bits (195), Expect = 4e-15
Identities = 57/188 (30%), Positives = 85/188 (45%), Gaps = 1/188 (0%)
Query: 63 LKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLK 121
L +PA +P + L+L N I + A LR++ L N++ + G+ GAL L+
Sbjct: 187 LTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLR 246
Query: 122 KLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDN 181
L L L N L+ VP LPR L L L N V+ + LT L+L N+L
Sbjct: 247 GLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASA 306
Query: 182 AFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPENYFNVIPKVAF 241
F+ L+ L L++A N L +P LP L L N + + + ++
Sbjct: 307 RVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRE 366
Query: 242 LRLNHNKL 249
L L HN+L
Sbjct: 367 LSLAHNRL 374
>gi|38202222 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 104 bits (260), Expect = 1e-22
Identities = 71/220 (32%), Positives = 113/220 (51%), Gaps = 5/220 (2%)
Query: 56 LYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEK 114
+Y + L E P +P + L+LQ N I TI L ++L+ N ++ IE+
Sbjct: 88 IYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEE 147
Query: 115 GALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
GA L LFL N L +P LPR++E+L+L N++S I + L +L L L
Sbjct: 148 GAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLD 207
Query: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLP-ANTMQLFLDNNSIEGIPENYF 233
N L ++ F L NL +L++ +N+L P LP N +L+L +N I +P N F
Sbjct: 208 GNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAF 267
Query: 234 NVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHN 272
+ + ++ L +++N LS+ LP F D+ +I L L +N
Sbjct: 268 SYLRQLYRLDMSNNNLSN--LPQGIFDDLDNITQLILRNN 305
Score = 89.4 bits (220), Expect = 5e-18
Identities = 75/260 (28%), Positives = 115/260 (44%), Gaps = 32/260 (12%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C F +YC +R L IP IP LYLQNN
Sbjct: 31 CPSVCRCDAGF---IYCNDRFLTSIPTGIPEDATTLYLQNN------------------- 68
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
+I N GI L L K+ ++L N L+E P+ LP+ +++L L N + I
Sbjct: 69 -----QINNAGIPSD-LKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYD 122
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
+ S + L L L +N + + + F+ L L +++N L +P LP +L L
Sbjct: 123 SLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRL 182
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSR-GFDVSSILDLQLSHNQLTKVP- 278
D+N I I + + L L+ N L++ GL + F++ ++ +L L N LT P
Sbjct: 183 DDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPV 242
Query: 279 -RISAHLQHLHLDHNKIKSV 297
+L+ L+L N I V
Sbjct: 243 NLPGTNLRKLYLQDNHINRV 262
Score = 45.1 bits (105), Expect = 1e-04
Identities = 42/145 (28%), Positives = 68/145 (46%), Gaps = 28/145 (19%)
Query: 204 LRNMPPRLPANTMQLFLDNNSIE--GIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDV 261
L ++P +P + L+L NN I GIP + N++ KV + L HN L + P+
Sbjct: 49 LTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLL-KVERIYLYHNSLDE--FPTNLPKY 105
Query: 262 SSILDLQ------LSHNQLTKVPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDS 315
L LQ ++++ L+K+P +L+ LHLD N + +V++ E +
Sbjct: 106 VKELHLQENNIRTITYDSLSKIP----YLEELHLDDNSVSAVSI------------EEGA 149
Query: 316 FSYGPHLRYLRLDGNEIKPPIPMAL 340
F +LR L L N + IP L
Sbjct: 150 FRDSNYLRLLFLSRNHLS-TIPWGL 173
>gi|7019383 fibronectin leucine rich transmembrane protein 3
precursor [Homo sapiens]
Length = 649
Score = 104 bits (260), Expect = 1e-22
Identities = 71/220 (32%), Positives = 113/220 (51%), Gaps = 5/220 (2%)
Query: 56 LYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEK 114
+Y + L E P +P + L+LQ N I TI L ++L+ N ++ IE+
Sbjct: 88 IYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYDSLSKIPYLEELHLDDNSVSAVSIEE 147
Query: 115 GALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
GA L LFL N L +P LPR++E+L+L N++S I + L +L L L
Sbjct: 148 GAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRLDDNRISTISSPSLQGLTSLKRLVLD 207
Query: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLP-ANTMQLFLDNNSIEGIPENYF 233
N L ++ F L NL +L++ +N+L P LP N +L+L +N I +P N F
Sbjct: 208 GNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPVNLPGTNLRKLYLQDNHINRVPPNAF 267
Query: 234 NVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHN 272
+ + ++ L +++N LS+ LP F D+ +I L L +N
Sbjct: 268 SYLRQLYRLDMSNNNLSN--LPQGIFDDLDNITQLILRNN 305
Score = 89.4 bits (220), Expect = 5e-18
Identities = 75/260 (28%), Positives = 115/260 (44%), Gaps = 32/260 (12%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C F +YC +R L IP IP LYLQNN
Sbjct: 31 CPSVCRCDAGF---IYCNDRFLTSIPTGIPEDATTLYLQNN------------------- 68
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
+I N GI L L K+ ++L N L+E P+ LP+ +++L L N + I
Sbjct: 69 -----QINNAGIPSD-LKNLLKVERIYLYHNSLDEFPTNLPKYVKELHLQENNIRTITYD 122
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
+ S + L L L +N + + + F+ L L +++N L +P LP +L L
Sbjct: 123 SLSKIPYLEELHLDDNSVSAVSIEEGAFRDSNYLRLLFLSRNHLSTIPWGLPRTIEELRL 182
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSR-GFDVSSILDLQLSHNQLTKVP- 278
D+N I I + + L L+ N L++ GL + F++ ++ +L L N LT P
Sbjct: 183 DDNRISTISSPSLQGLTSLKRLVLDGNLLNNHGLGDKVFFNLVNLTELSLVRNSLTAAPV 242
Query: 279 -RISAHLQHLHLDHNKIKSV 297
+L+ L+L N I V
Sbjct: 243 NLPGTNLRKLYLQDNHINRV 262
Score = 45.1 bits (105), Expect = 1e-04
Identities = 42/145 (28%), Positives = 68/145 (46%), Gaps = 28/145 (19%)
Query: 204 LRNMPPRLPANTMQLFLDNNSIE--GIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDV 261
L ++P +P + L+L NN I GIP + N++ KV + L HN L + P+
Sbjct: 49 LTSIPTGIPEDATTLYLQNNQINNAGIPSDLKNLL-KVERIYLYHNSLDE--FPTNLPKY 105
Query: 262 SSILDLQ------LSHNQLTKVPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDS 315
L LQ ++++ L+K+P +L+ LHLD N + +V++ E +
Sbjct: 106 VKELHLQENNIRTITYDSLSKIP----YLEELHLDDNSVSAVSI------------EEGA 149
Query: 316 FSYGPHLRYLRLDGNEIKPPIPMAL 340
F +LR L L N + IP L
Sbjct: 150 FRDSNYLRLLFLSRNHLS-TIPWGL 173
>gi|7019381 fibronectin leucine rich transmembrane protein 2 [Homo
sapiens]
Length = 660
Score = 103 bits (258), Expect = 2e-22
Identities = 62/196 (31%), Positives = 102/196 (52%), Gaps = 2/196 (1%)
Query: 56 LYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEK 114
+Y L E P +P + L+LQ N I+TI +L ++L+ N I+ G+E
Sbjct: 93 VYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGVED 152
Query: 115 GALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQ 174
GA + L LFL N L VP LP L++L++ N+++ I F NL +L L +
Sbjct: 153 GAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVD 212
Query: 175 NNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLP-ANTMQLFLDNNSIEGIPENYF 233
N L + TF L L + ++ +N+L + PP LP + ++L+L +N I IP F
Sbjct: 213 GNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAF 272
Query: 234 NVIPKVAFLRLNHNKL 249
+ + K+ L +++N+L
Sbjct: 273 SNLRKLERLDISNNQL 288
Score = 84.3 bits (207), Expect = 1e-16
Identities = 66/260 (25%), Positives = 114/260 (43%), Gaps = 32/260 (12%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIP-AIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C +F +YC R L +P IP + LYL NN
Sbjct: 36 CPSVCRCDRNF---VYCNERSLTSVPLGIPEGVTVLYLHNN------------------- 73
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
+I N G L ++ + ++L N+L+E P LP+++ L L N + I +
Sbjct: 74 -----QINNAGFP-AELHNVQSVHTVYLYGNQLDEFPMNLPKNVRVLHLQENNIQTISRA 127
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLFL 220
+ L L L L +N + + F+ +L L ++KN L ++P LP + +L +
Sbjct: 128 ALAQLLKLEELHLDDNSISTVGVEDGAFREAISLKLLFLSKNHLSSVPVGLPVDLQELRV 187
Query: 221 DNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFD-VSSILDLQLSHNQLTKVP- 278
D N I I + F + + L ++ N L+++G+ F ++ + + + N L+ P
Sbjct: 188 DENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAEGTFSHLTKLKEFSIVRNSLSHPPP 247
Query: 279 -RISAHLQHLHLDHNKIKSV 297
HL L+L N+I +
Sbjct: 248 DLPGTHLIRLYLQDNQINHI 267
Score = 62.0 bits (149), Expect = 8e-10
Identities = 42/147 (28%), Positives = 67/147 (45%), Gaps = 26/147 (17%)
Query: 56 LYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEK 114
L+ L +P +P + L + N I I + F+N T L + ++ N +TN GI +
Sbjct: 164 LFLSKNHLSSVPVGLPVDLQELRVDENRIAVISDMAFQNLTSLERLIVDGNLLTNKGIAE 223
Query: 115 GALSQLKKL----------------------LFLFLEDNELEEVPSPL---PRSLEQLQL 149
G S L KL + L+L+DN++ +P R LE+L +
Sbjct: 224 GTFSHLTKLKEFSIVRNSLSHPPPDLPGTHLIRLYLQDNQINHIPLTAFSNLRKLERLDI 283
Query: 150 ARNKVSRIPQGTFSNLENLTLLDLQNN 176
+ N++ + QG F NL NL L +NN
Sbjct: 284 SNNQLRMLTQGVFDNLSNLKQLTARNN 310
Score = 33.1 bits (74), Expect = 0.38
Identities = 31/107 (28%), Positives = 47/107 (43%), Gaps = 15/107 (14%)
Query: 201 KNALRNMPPRLPANTMQLFLDNNSIE--GIPENYFNVIPKVAFLRLNHNKLSD--EGLPS 256
+ +L ++P +P L+L NN I G P NV V + L N+L + LP
Sbjct: 51 ERSLTSVPLGIPEGVTVLYLHNNQINNAGFPAELHNV-QSVHTVYLYGNQLDEFPMNLPK 109
Query: 257 RGFDVSSILDLQLSHNQLTKVPRISA----HLQHLHLDHNKIKSVNV 299
++ L L N + + R + L+ LHLD N I +V V
Sbjct: 110 ------NVRVLHLQENNIQTISRAALAQLLKLEELHLDDNSISTVGV 150
>gi|20302168 toll-like receptor 8 [Homo sapiens]
Length = 1041
Score = 99.0 bits (245), Expect = 6e-21
Identities = 84/294 (28%), Positives = 135/294 (45%), Gaps = 42/294 (14%)
Query: 58 CENRGLKEIP-AIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNY------ 110
C NR L+E+P + + L L +N I I + F+ L INLN N +
Sbjct: 49 CSNRRLQEVPQTVGKYVTELDLSDNFITHITNESFQGLQNLTKINLNHNPNVQHQNGNPG 108
Query: 111 ------GIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSN 164
I GA LK L L LEDN+L ++PS LP SL +L L +N + I + S
Sbjct: 109 IQSNGLNITDGAFLNLKNLRELLLEDNQLPQIPSGLPESLTELSLIQNNIYNITKEGISR 168
Query: 165 LENLTLLDLQNNKLVDNAFQR-----DTFKGLKNLMQLNMAKNALRNMPPRLPANTMQLF 219
L NL L L N + ++ F+ L NL L+++ N+L ++PP+LP++ +LF
Sbjct: 169 LINLKNLYLAWNCYFNKVCEKTNIEDGVFETLTNLELLSLSFNSLSHVPPKLPSSLRKLF 228
Query: 220 LDNNSIEGIPENYFNVIPKVAFLRLNHN--KLSDEGLPSRGFDVSSILDL-QLSHNQLTK 276
L N I+ I E F + + L L+ N + + P D + +++ + + LT+
Sbjct: 229 LSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASINIDRFAFQNLTQ 288
Query: 277 VPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGN 330
L++L+L ++ +N + F PHL+ L L+ N
Sbjct: 289 -------LRYLNLSSTSLRKINAA--------------WFKNMPHLKVLDLEFN 321
Score = 60.8 bits (146), Expect = 2e-09
Identities = 79/276 (28%), Positives = 121/276 (43%), Gaps = 54/276 (19%)
Query: 76 LYLQNNLIETIPEKPFENATQLRWINL--NKNKITNYGIEKGALSQLKKLLFLFLEDNEL 133
L L N I I FEN + +NL N N G E A+ +K +L L +N L
Sbjct: 486 LDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVK---YLDLTNNRL 542
Query: 134 E-EVPSPLPR--SLEQLQLARNK-VSRIPQGT-----FSNLENLTLLDLQNNK------- 177
+ + S L LE L L+ N RI T N NL +L+L +N
Sbjct: 543 DFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDK 602
Query: 178 -------LVDNAFQRDT---------------FKGLKNLMQLNMAKNALRNMPP----RL 211
LV+ F + FKGLKNL +L+++ N L+++P L
Sbjct: 603 YNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKNLTRLDLSLNRLKHIPNEAFLNL 662
Query: 212 PANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSH 271
PA+ +L +++N ++ P++ L L NKL F SS+ L LSH
Sbjct: 663 PASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKLLFLTDSLSDF-TSSLRTLLLSH 721
Query: 272 NQLTKVP-----RISAHLQHLHLDHNKIKSVNVSVI 302
N+++ +P +S+ L+HL L N +K++N S +
Sbjct: 722 NRISHLPSGFLSEVSS-LKHLDLSSNLLKTINKSAL 756
Score = 35.8 bits (81), Expect = 0.059
Identities = 35/151 (23%), Positives = 61/151 (40%), Gaps = 20/151 (13%)
Query: 67 PAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGI-------EKGALSQ 119
P +PS + L+L N I+ I E+ F+ L ++L+ N + + GA
Sbjct: 218 PKLPSSLRKLFLSNTQIKYISEEDFKGLINLTLLDLSGNCPRCFNAPFPCVPCDGGASIN 277
Query: 120 LKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLV 179
+ + F L L L L+ + +I F N+ +L +LDL+ N LV
Sbjct: 278 IDRFAFQNLTQ-------------LRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLV 324
Query: 180 DNAFQRDTFKGLKNLMQLNMAKNALRNMPPR 210
L L L+++ N ++ P+
Sbjct: 325 GEIASGAFLTMLPRLEILDLSFNYIKGSYPQ 355
Score = 35.0 bits (79), Expect = 0.10
Identities = 50/221 (22%), Positives = 83/221 (37%), Gaps = 41/221 (18%)
Query: 125 FLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLV----- 179
++F E E + P +L + L N + +I F N NL ++ L N++
Sbjct: 377 YVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKD 436
Query: 180 -------DNAFQRDTFKGLKNLMQLNMAKNALRN----MPPRLPANTMQLFLDNNSIEGI 228
++FQR K + + N + P+ A L L NSI I
Sbjct: 437 TRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFI 496
Query: 229 PENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAHLQHLH 288
N F +P +A L L+ N + LS + + +P H+++L
Sbjct: 497 GPNQFENLPDIACLNLSANSNAQ----------------VLSGTEFSAIP----HVKYLD 536
Query: 289 LDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDG 329
L +N++ N S + + E SY H Y R+ G
Sbjct: 537 LTNNRLDFDNASAL---TELSDLEVLDLSYNSH--YFRIAG 572
Score = 35.0 bits (79), Expect = 0.10
Identities = 62/253 (24%), Positives = 93/253 (36%), Gaps = 65/253 (25%)
Query: 92 ENATQLRWINLNKNKI----TNYGIEKGALSQL-------------------------KK 122
+N T L+ +NL+ N I Y +E +L +L K
Sbjct: 581 QNFTNLKVLNLSHNNIYTLTDKYNLESKSLVELVFSGNRLDILWNDDDNRYISIFKGLKN 640
Query: 123 LLFLFLEDNELEEVPSP----LPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKL 178
L L L N L+ +P+ LP SL +L + N + L LLDL+ NKL
Sbjct: 641 LTRLDLSLNRLKHIPNEAFLNLPASLTELHINDNMLKFFNWTLLQQFPRLELLDLRGNKL 700
Query: 179 VDNAFQRDTFKGL-KNLMQLNMAKNALRNMPPRLPANTMQL-FLDNNSIEGIPENYFNVI 236
+ F D+ +L L ++ N + ++P + L LD +S N I
Sbjct: 701 L---FLTDSLSDFTSSLRTLLLSHNRISHLPSGFLSEVSSLKHLDLSS------NLLKTI 751
Query: 237 PKVAFLRLNHNKLSDEGLPSRGFDVS-SILDLQ--LSHNQLTKVPRISAHLQHLHLDHNK 293
K A KLS L F+ + I D + + + K+PR+
Sbjct: 752 NKSALETKTTTKLSMLELHGNPFECTCDIGDFRRWMDEHLNVKIPRL------------- 798
Query: 294 IKSVNVSVICPSP 306
V VIC SP
Sbjct: 799 -----VDVICASP 806
>gi|157694513 leucine-rich repeat-containing G protein-coupled
receptor 4 [Homo sapiens]
Length = 951
Score = 98.6 bits (244), Expect = 7e-21
Identities = 84/257 (32%), Positives = 132/257 (51%), Gaps = 23/257 (8%)
Query: 62 GLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLK 121
GLKE+ L LQNN ++T+P + + L+ + L+ N IT+ + + + L
Sbjct: 103 GLKELKV-------LTLQNNQLKTVPSEAIRGLSALQSLRLDANHITS--VPEDSFEGLV 153
Query: 122 KLLFLFLEDNELEEVP----SPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNK 177
+L L+L+DN L EVP S LP +L+ L LA NK+S IP F+NL +L +L L NNK
Sbjct: 154 QLRHLWLDDNSLTEVPVHPLSNLP-TLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNK 212
Query: 178 LVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPA--NTMQLFLDNNSIEGIPENYFNV 235
+ + + F GL NL L++ N L P + A + +L +NSI IP+ F+
Sbjct: 213 I--RSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDG 270
Query: 236 IPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQL-SHNQLTKVPRI--SAHLQHLHLDHN 292
P + + L N LS G S ++S + L + + + + P + + HL+ L L
Sbjct: 271 NPLLRTIHLYDNPLSFVG-NSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGT 329
Query: 293 KIKSVNVSVICPSPSML 309
KI S+ + +C ML
Sbjct: 330 KISSI-PNNLCQEQKML 345
Score = 43.5 bits (101), Expect = 3e-04
Identities = 38/122 (31%), Positives = 60/122 (49%), Gaps = 8/122 (6%)
Query: 91 FENAT---QLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLP-RSLEQ 146
F N T L + L KI++ I + K L L L N + ++PS +LE+
Sbjct: 312 FPNLTGTVHLESLTLTGTKISS--IPNNLCQEQKMLRTLDLSYNNIRDLPSFNGCHALEE 369
Query: 147 LQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRN 206
+ L RN++ +I +GTF L +L +LDL N L+ R F L + L+++ N L +
Sbjct: 370 ISLQRNQIYQIKEGTFQGLISLRILDLSRN-LIHEIHSR-AFATLGPITNLDVSFNELTS 427
Query: 207 MP 208
P
Sbjct: 428 FP 429
>gi|4504379 leucine-rich repeat-containing G protein-coupled
receptor 5 [Homo sapiens]
Length = 907
Score = 93.2 bits (230), Expect = 3e-19
Identities = 87/301 (28%), Positives = 133/301 (44%), Gaps = 33/301 (10%)
Query: 42 CPMECFCPPSFPTALY--CENRGLKEIPAIPSRIW-YLYLQNNLIETIPEKPFENATQLR 98
CP C C P L C + GL E+P+ S YL L N I + P + L
Sbjct: 34 CPTHCHCEPDGRMLLRVDCSDLGLSELPSNLSVFTSYLDLSMNNISQLLPNPLPSLRFLE 93
Query: 99 WINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPL---PRSLEQLQLARNKVS 155
+ L N +T I KGA + L L L L++N+L VP+ RSL+ L+L N +S
Sbjct: 94 ELRLAGNALTY--IPKGAFTGLYSLKVLMLQNNQLRHVPTEALQNLRSLQSLRLDANHIS 151
Query: 156 RIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPAN- 214
+P FS L +L L L +N L + Q F+ L L + +A N + ++P N
Sbjct: 152 YVPPSCFSGLHSLRHLWLDDNALTEIPVQ--AFRSLSALQAMTLALNKIHHIPDYAFGNL 209
Query: 215 --TMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHN 272
+ L L NN I + + F+ + + L LN+N L + P+ +S++ +L N
Sbjct: 210 SSLVVLHLHNNRIHSLGKKCFDGLHSLETLDLNYNNLDE--FPTAIRTLSNLKELGFHSN 267
Query: 273 QLTKVPRI----SAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLD 328
+ +P + L +H N I+ V R +F + P LR L L+
Sbjct: 268 NIRSIPEKAFVGNPSLITIHFYDNPIQFVG--------------RSAFQHLPELRTLTLN 313
Query: 329 G 329
G
Sbjct: 314 G 314
Score = 57.4 bits (137), Expect = 2e-08
Identities = 78/288 (27%), Positives = 122/288 (42%), Gaps = 46/288 (15%)
Query: 41 ECPMECFCPPSFPTALYCENRGLKEIPAIP-------SRIWYLYLQNNLIETIPEKPFEN 93
E P++ F S AL L +I IP S + L+L NN I ++ +K F+
Sbjct: 176 EIPVQAFRSLS---ALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDG 232
Query: 94 ATQLRWINLNKNKITNYGIEKGALSQLKKLLF---------------------LFLEDNE 132
L ++LN N + + LS LK+L F + DN
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELGFHSNNIRSIPEKAFVGNPSLITIHFYDNP 292
Query: 133 LEEVPSPLPRSLEQLQ-LARNKVSRIPQ-----GTFSNLENLTLLDLQNNKLVDNAFQRD 186
++ V + L +L+ L N S+I + GT +NLE+LTL Q + L +
Sbjct: 293 IQFVGRSAFQHLPELRTLTLNGASQITEFPDLTGT-ANLESLTLTGAQISSLPQTVCNQ- 350
Query: 187 TFKGLKNLMQLNMAKNALRNMPPRLPANTMQ-LFLDNNSIEGIPENYFNVIPKVAFLRLN 245
L NL L+++ N L ++P +Q + L +N I I + F + + L L
Sbjct: 351 ----LPNLQVLDLSYNLLEDLPSFSVCQKLQKIDLRHNEIYEIKVDTFQQLLSLRSLNLA 406
Query: 246 HNKLSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISAH-LQHLHLDHN 292
NK++ P+ + S++ L LS N L+ P H L HL L N
Sbjct: 407 WNKIAIIH-PNAFSTLPSLIKLDLSSNLLSSFPITGLHGLTHLKLTGN 453
>gi|122937309 leucine rich repeat containing 4B [Homo sapiens]
Length = 713
Score = 92.8 bits (229), Expect = 4e-19
Identities = 82/261 (31%), Positives = 122/261 (46%), Gaps = 16/261 (6%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP+ C C + + C R L E+PA IP YL LQ N I+ I F++ L +
Sbjct: 57 CPVACSCSNQ-ASRVICTRRDLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEIL 115
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPS---PLPRSLEQLQLARNKVSRI 157
L+KN + IE GA + L L L L DN L VP+ L +L L N + I
Sbjct: 116 QLSKNLVRK--IEVGAFNGLPSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESI 173
Query: 158 PQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLP-ANTM 216
P F+ + +L LDL K ++ F+GL NL LN+ L+++P
Sbjct: 174 PSYAFNRVPSLRRLDLGELKRLE-YISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLE 232
Query: 217 QLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHNQLT 275
+L L N ++ I F + + L L H +++ + F D+ S+ +L LSHN L
Sbjct: 233 ELELSGNRLDLIRPGSFQGLTSLRKLWLMHAQVAT--IERNAFDDLKSLEELNLSHNNLM 290
Query: 276 KVPR---ISAH-LQHLHLDHN 292
+P H L+ +HL+HN
Sbjct: 291 SLPHDLFTPLHRLERVHLNHN 311
Score = 59.7 bits (143), Expect = 4e-09
Identities = 47/168 (27%), Positives = 77/168 (45%), Gaps = 7/168 (4%)
Query: 132 ELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGL 191
+L EVP+ +P + L L N + I TF +L +L +L L N + + F GL
Sbjct: 76 DLAEVPASIPVNTRYLNLQENGIQVIRTDTFKHLRHLEILQLSKNLV--RKIEVGAFNGL 133
Query: 192 KNLMQLNMAKNALRNMPPR---LPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNK 248
+L L + N L +P + + +L+L NN IE IP FN +P + L L K
Sbjct: 134 PSLNTLELFDNRLTTVPTQAFEYLSKLRELWLRNNPIESIPSYAFNRVPSLRRLDLGELK 193
Query: 249 LSDEGLPSRGFDVSSILDLQLSHNQLTKVPRISA--HLQHLHLDHNKI 294
+ + + ++ L L L +P ++A L+ L L N++
Sbjct: 194 RLEYISEAAFEGLVNLRYLNLGMCNLKDIPNLTALVRLEELELSGNRL 241
>gi|153251229 chondroadherin precursor [Homo sapiens]
Length = 359
Score = 92.8 bits (229), Expect = 4e-19
Identities = 72/268 (26%), Positives = 124/268 (46%), Gaps = 19/268 (7%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENATQLRWIN 101
CP C C + C+ GL++IP + + L LQ N + F L ++
Sbjct: 23 CPQNCHCHSDLQHVI-CDKVGLQKIPKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLH 81
Query: 102 LNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQ---LARNKVSRIP 158
L +I + GA LK+L++L+L N++ + + L +L L NKV+ +P
Sbjct: 82 LQHCQIRE--VAAGAFRGLKQLIYLYLSHNDIRVLRAGAFDDLTELTYLYLDHNKVTELP 139
Query: 159 QGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRL---PANT 215
+G S L NL +L L NNK+ + F+G K+L L +++NAL ++ P N
Sbjct: 140 RGLLSPLVNLFILQLNNNKI--RELRAGAFQGAKDLRWLYLSENALSSLQPGALDDVENL 197
Query: 216 MQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSS--ILDLQLSHNQ 273
+ +D N + P + + V L+L+HN L + +P F + L L +
Sbjct: 198 AKFHVDRNQLSSYPSAALSKLRVVEELKLSHNPL--KSIPDNAFQSFGRYLETLWLDNTN 255
Query: 274 LTKVPRIS----AHLQHLHLDHNKIKSV 297
L K + L+H+HL++N++ +
Sbjct: 256 LEKFSDGAFLGVTTLKHVHLENNRLNQL 283
Score = 42.0 bits (97), Expect = 8e-04
Identities = 38/148 (25%), Positives = 66/148 (44%), Gaps = 19/148 (12%)
Query: 209 PRLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPS-RGFDVSSILDL 267
P++ T L L N+ + N F +P + L L H ++ + + RG + ++ L
Sbjct: 47 PKVSEKTKLLNLQRNNFPVLAANSFRAMPNLVSLHLQHCQIREVAAGAFRG--LKQLIYL 104
Query: 268 QLSHNQLTKVPRISA-----HLQHLHLDHNKIKSVNVSVICPSPSMLPAERD-------- 314
LSHN + +V R A L +L+LDHNK+ + ++ P ++ + +
Sbjct: 105 YLSHNDI-RVLRAGAFDDLTELTYLYLDHNKVTELPRGLLSPLVNLFILQLNNNKIRELR 163
Query: 315 --SFSYGPHLRYLRLDGNEIKPPIPMAL 340
+F LR+L L N + P AL
Sbjct: 164 AGAFQGAKDLRWLYLSENALSSLQPGAL 191
Score = 33.9 bits (76), Expect = 0.23
Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 20/107 (18%)
Query: 51 SFPTALYCENRGLKEIPAIPSRIWYLYLQNNLIETIPEKPFENA---TQLRWI-NLNKNK 106
S+P+A + R ++E L L +N +++IP+ F++ + W+ N N K
Sbjct: 209 SYPSAALSKLRVVEE----------LKLSHNPLKSIPDNAFQSFGRYLETLWLDNTNLEK 258
Query: 107 ITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLP-RSLEQLQLARN 152
++ GA + L + LE+N L ++PS P SLE L L N
Sbjct: 259 FSD-----GAFLGVTTLKHVHLENNRLNQLPSNFPFDSLETLALTNN 300
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 92.4 bits (228), Expect = 5e-19
Identities = 77/261 (29%), Positives = 122/261 (46%), Gaps = 16/261 (6%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIP-AIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C F + C + L+E+P I + L L N I+ I F++ L +
Sbjct: 47 CPSVCSCSNQFSKVI-CVRKNLREVPDGISTNTRLLNLHENQIQIIKVNSFKHLRHLEIL 105
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPL---PRSLEQLQLARNKVSRI 157
L++N I IE GA + L L L L DN L +P+ L++L L N + I
Sbjct: 106 QLSRNHIRT--IEIGAFNGLANLNTLELFDNRLTTIPNGAFVYLSKLKELWLRNNPIESI 163
Query: 158 PQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTM- 216
P F+ + +L LDL K + + F+GL NL LN+A LR +P P +
Sbjct: 164 PSYAFNRIPSLRRLDLGELKRL-SYISEGAFEGLSNLRYLNLAMCNLREIPNLTPLIKLD 222
Query: 217 QLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFD-VSSILDLQLSHNQLT 275
+L L N + I F + + L + +++ + + FD + S++++ L+HN LT
Sbjct: 223 ELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQI--QVIERNAFDNLQSLVEINLAHNNLT 280
Query: 276 KVPRISA----HLQHLHLDHN 292
+P HL+ +HL HN
Sbjct: 281 LLPHDLFTPLHHLERIHLHHN 301
>gi|198041768 synleurin [Homo sapiens]
Length = 622
Score = 91.7 bits (226), Expect = 9e-19
Identities = 82/287 (28%), Positives = 138/287 (48%), Gaps = 32/287 (11%)
Query: 58 CENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGA 116
C N GL IP P +LYL N I I E L + L+ + I + A
Sbjct: 46 CRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILY--VYPKA 103
Query: 117 LSQLKKLLFLFLEDNELEEVPSPLPR---SLEQLQLARNKVSRIPQGTFSNLENLTLLDL 173
QL+ L FLFL +N ++ + + + +L L L N+VS +P+G F++L ++ L+L
Sbjct: 104 FVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQVSFVPRGVFNDLVSVQYLNL 163
Query: 174 QNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPP---RLPANTMQLFLDNNSIEGIPE 230
Q N+L TF G+ L L+++ N + + + N L+L +N++ +P
Sbjct: 164 QRNRL--TVLGSGTFVGMVALRILDLSNNNILRISESGFQHLENLACLYLGSNNLTKVPS 221
Query: 231 NYFNVIPKVAFLRLNHNKLSDEGLPSRGF-DVSSILDLQLSHNQLTKVPRIS----AHLQ 285
N F V+ + L L+HN + E + F ++++ L L ++++ V R +L+
Sbjct: 222 NAFEVLKSLRRLSLSHNPI--EAIQPFAFKGLANLEYLLLKNSRIRNVTRDGFSGINNLK 279
Query: 286 HLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEI 332
HL L HN ++++N D+FS +L YL+LD N I
Sbjct: 280 HLILSHNDLENLN--------------SDTFSLLKNLIYLKLDRNRI 312
Score = 54.7 bits (130), Expect = 1e-07
Identities = 42/140 (30%), Positives = 71/140 (50%), Gaps = 8/140 (5%)
Query: 76 LYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEE 135
LYL +N + +P FE LR ++L+ N I I+ A L L +L L+++ +
Sbjct: 209 LYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIE--AIQPFAFKGLANLEYLLLKNSRIRN 266
Query: 136 VPSPL---PRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGL- 191
V +L+ L L+ N + + TFS L+NL L L N+++ + DTF+ +
Sbjct: 267 VTRDGFSGINNLKHLILSHNDLENLNSDTFSLLKNLIYLKLDRNRII--SIDNDTFENMG 324
Query: 192 KNLMQLNMAKNALRNMPPRL 211
+L LN++ N L + PR+
Sbjct: 325 ASLKILNLSFNNLTALHPRV 344
Score = 32.7 bits (73), Expect = 0.50
Identities = 35/129 (27%), Positives = 57/129 (44%), Gaps = 33/129 (25%)
Query: 196 QLNMAKNALRNMPPRLPANTMQLFLDNNSIEGIPE-----------------NYFNVIPK 238
Q+N L ++P P +T+ L+L N+I I E N V PK
Sbjct: 43 QINCRNLGLSSIPKNFPESTVFLYLTGNNISYINESELTGLHSLVALYLDNSNILYVYPK 102
Query: 239 -------VAFLRLNHN--KLSDEGLPSRGFDVSSILDLQLSHNQLTKVPR----ISAHLQ 285
+ FL LN+N K D G+ + ++ +L L +NQ++ VPR +Q
Sbjct: 103 AFVQLRHLYFLFLNNNFIKRLDPGIFK---GLLNLRNLYLQYNQVSFVPRGVFNDLVSVQ 159
Query: 286 HLHLDHNKI 294
+L+L N++
Sbjct: 160 YLNLQRNRL 168
>gi|205277468 leucine rich repeat containing 15 isoform a [Homo
sapiens]
Length = 587
Score = 90.5 bits (223), Expect = 2e-18
Identities = 85/297 (28%), Positives = 138/297 (46%), Gaps = 26/297 (8%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP EC C S + + C + +P +P L + N I + E PF N + L +
Sbjct: 31 CPSECTC--SRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIAL 88
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPR---SLEQLQLARNKVSRI 157
+ KN+++ I GA L L +L L +N+L+ +P L + SLE L L+ N++ +I
Sbjct: 89 RIEKNELSR--ITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQI 146
Query: 158 PQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRL---PAN 214
FS NL L L N L F L L +LN+ KN+L ++ PR+ N
Sbjct: 147 QPAHFSQCSNLKELQLHGNHL--EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGN 204
Query: 215 TMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF--DVSSILDLQLSHN 272
L L N + IP F+ + + L L N++ GL S G + ++ L LS+N
Sbjct: 205 LQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQI---GLLSPGLFHNNHNLQRLYLSNN 261
Query: 273 QLTKVP----RISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYL 325
++++P L L L N +K +++ + P P++ R+ + Y H+ L
Sbjct: 262 HISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNL----RELWLYDNHISSL 314
Score = 77.0 bits (188), Expect = 2e-14
Identities = 65/237 (27%), Positives = 116/237 (48%), Gaps = 15/237 (6%)
Query: 71 SRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLED 130
S + L L N +E IP+ F++ L +NL KN +T+ I L L L L +
Sbjct: 155 SNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTH--ISPRVFQHLGNLQVLRLYE 212
Query: 131 NELEEVPSPL---PRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDT 187
N L ++P +L++L L +N++ + G F N NL L L NN + +
Sbjct: 213 NRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHI--SQLPPSI 270
Query: 188 FKGLKNLMQLNMAKNALRNMPPRL---PANTMQLFLDNNSIEGIPENYFNVIPKVAFLRL 244
F L L +L + N+L+ + + N +L+L +N I +P+N F+ + ++ L L
Sbjct: 271 FMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLIL 330
Query: 245 NHNKLSDEGLPSRGFDVSSILDLQLSHNQLT----KVPRISAHLQHLHLDHNKIKSV 297
+ N++S P ++ + +L L N L V R+ A+LQ++ L +N+++ +
Sbjct: 331 SRNQISFIS-PGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQL 386
Score = 73.2 bits (178), Expect = 3e-13
Identities = 63/205 (30%), Positives = 101/205 (49%), Gaps = 15/205 (7%)
Query: 76 LYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEE 135
L LQ N I + F N L+ + L+ N I+ + QL +L L L N L+E
Sbjct: 232 LALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ--LPPSIFMQLPQLNRLTLFGNSLKE 289
Query: 136 VP----SPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGL 191
+ P+P +L +L L N +S +P FSNL L +L L N++ + F GL
Sbjct: 290 LSLGIFGPMP-NLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQI--SFISPGAFNGL 346
Query: 192 KNLMQLNMAKNALRNMPP---RLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNK 248
L +L++ NAL+++ R+ AN + L NN + +P N F + + ++L +N+
Sbjct: 347 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 406
Query: 249 LSDEGLPSRGFD-VSSILDLQLSHN 272
L E LP FD + + +L+L N
Sbjct: 407 L--ENLPLGIFDHLGKLCELRLYDN 429
Score = 64.7 bits (156), Expect = 1e-10
Identities = 75/263 (28%), Positives = 114/263 (43%), Gaps = 47/263 (17%)
Query: 132 ELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGL 191
EL E P +L L++ +N++SRI G F NL +L L L NNKL F+GL
Sbjct: 73 ELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKL--QVLPIGLFQGL 130
Query: 192 KNLMQLNMAKNALRNMPP---RLPANTMQLFLDNNSIEGIPENYF--------------- 233
+L L ++ N L + P +N +L L N +E IP+ F
Sbjct: 131 DSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNS 190
Query: 234 --NVIPKV-------AFLRLNHNKLSDEGLPSRGFD-VSSILDLQLSHNQLTKVPRISAH 283
++ P+V LRL N+L+D +P FD + ++ +L L NQ+ + H
Sbjct: 191 LTHISPRVFQHLGNLQVLRLYENRLTD--IPMGTFDGLVNLQELALQQNQIGLLSPGLFH 248
Query: 284 ----LQHLHLDHNKIKSVNVSVICPSP----------SMLPAERDSFSYGPHLRYLRLDG 329
LQ L+L +N I + S+ P S+ F P+LR L L
Sbjct: 249 NNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYD 308
Query: 330 NEIKPPIPMALMTCFRLLQAVII 352
N I +P + + R LQ +I+
Sbjct: 309 NHIS-SLPDNVFSNLRQLQVLIL 330
Score = 58.5 bits (140), Expect = 9e-09
Identities = 42/133 (31%), Positives = 70/133 (52%), Gaps = 7/133 (5%)
Query: 76 LYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEE 135
L+L +N I ++P+ F N QL+ + L++N+I+ I GA + L +L L L N L++
Sbjct: 304 LWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF--ISPGAFNGLTELRELSLHTNALQD 361
Query: 136 VPSPLPRSLEQLQ---LARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLK 192
+ + R L LQ L N++ ++P F+N+ L + LQNN+L + F L
Sbjct: 362 LDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLEN--LPLGIFDHLG 419
Query: 193 NLMQLNMAKNALR 205
L +L + N R
Sbjct: 420 KLCELRLYDNPWR 432
>gi|18677767 leucine rich repeat containing 15 isoform b [Homo
sapiens]
Length = 581
Score = 90.5 bits (223), Expect = 2e-18
Identities = 85/297 (28%), Positives = 138/297 (46%), Gaps = 26/297 (8%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIPA-IPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP EC C S + + C + +P +P L + N I + E PF N + L +
Sbjct: 25 CPSECTC--SRASQVECTGARIVAVPTPLPWNAMSLQILNTHITELNESPFLNISALIAL 82
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPR---SLEQLQLARNKVSRI 157
+ KN+++ I GA L L +L L +N+L+ +P L + SLE L L+ N++ +I
Sbjct: 83 RIEKNELSR--ITPGAFRNLGSLRYLSLANNKLQVLPIGLFQGLDSLESLLLSSNQLLQI 140
Query: 158 PQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRL---PAN 214
FS NL L L N L F L L +LN+ KN+L ++ PR+ N
Sbjct: 141 QPAHFSQCSNLKELQLHGNHL--EYIPDGAFDHLVGLTKLNLGKNSLTHISPRVFQHLGN 198
Query: 215 TMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGF--DVSSILDLQLSHN 272
L L N + IP F+ + + L L N++ GL S G + ++ L LS+N
Sbjct: 199 LQVLRLYENRLTDIPMGTFDGLVNLQELALQQNQI---GLLSPGLFHNNHNLQRLYLSNN 255
Query: 273 QLTKVP----RISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYL 325
++++P L L L N +K +++ + P P++ R+ + Y H+ L
Sbjct: 256 HISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNL----RELWLYDNHISSL 308
Score = 77.0 bits (188), Expect = 2e-14
Identities = 65/237 (27%), Positives = 116/237 (48%), Gaps = 15/237 (6%)
Query: 71 SRIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLED 130
S + L L N +E IP+ F++ L +NL KN +T+ I L L L L +
Sbjct: 149 SNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNSLTH--ISPRVFQHLGNLQVLRLYE 206
Query: 131 NELEEVPSPL---PRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDT 187
N L ++P +L++L L +N++ + G F N NL L L NN + +
Sbjct: 207 NRLTDIPMGTFDGLVNLQELALQQNQIGLLSPGLFHNNHNLQRLYLSNNHI--SQLPPSI 264
Query: 188 FKGLKNLMQLNMAKNALRNMPPRL---PANTMQLFLDNNSIEGIPENYFNVIPKVAFLRL 244
F L L +L + N+L+ + + N +L+L +N I +P+N F+ + ++ L L
Sbjct: 265 FMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYDNHISSLPDNVFSNLRQLQVLIL 324
Query: 245 NHNKLSDEGLPSRGFDVSSILDLQLSHNQLT----KVPRISAHLQHLHLDHNKIKSV 297
+ N++S P ++ + +L L N L V R+ A+LQ++ L +N+++ +
Sbjct: 325 SRNQISFIS-PGAFNGLTELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQL 380
Score = 73.2 bits (178), Expect = 3e-13
Identities = 63/205 (30%), Positives = 101/205 (49%), Gaps = 15/205 (7%)
Query: 76 LYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEE 135
L LQ N I + F N L+ + L+ N I+ + QL +L L L N L+E
Sbjct: 226 LALQQNQIGLLSPGLFHNNHNLQRLYLSNNHISQ--LPPSIFMQLPQLNRLTLFGNSLKE 283
Query: 136 VP----SPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGL 191
+ P+P +L +L L N +S +P FSNL L +L L N++ + F GL
Sbjct: 284 LSLGIFGPMP-NLRELWLYDNHISSLPDNVFSNLRQLQVLILSRNQI--SFISPGAFNGL 340
Query: 192 KNLMQLNMAKNALRNMPP---RLPANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNK 248
L +L++ NAL+++ R+ AN + L NN + +P N F + + ++L +N+
Sbjct: 341 TELRELSLHTNALQDLDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQ 400
Query: 249 LSDEGLPSRGFD-VSSILDLQLSHN 272
L E LP FD + + +L+L N
Sbjct: 401 L--ENLPLGIFDHLGKLCELRLYDN 423
Score = 64.7 bits (156), Expect = 1e-10
Identities = 75/263 (28%), Positives = 114/263 (43%), Gaps = 47/263 (17%)
Query: 132 ELEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGL 191
EL E P +L L++ +N++SRI G F NL +L L L NNKL F+GL
Sbjct: 67 ELNESPFLNISALIALRIEKNELSRITPGAFRNLGSLRYLSLANNKL--QVLPIGLFQGL 124
Query: 192 KNLMQLNMAKNALRNMPP---RLPANTMQLFLDNNSIEGIPENYF--------------- 233
+L L ++ N L + P +N +L L N +E IP+ F
Sbjct: 125 DSLESLLLSSNQLLQIQPAHFSQCSNLKELQLHGNHLEYIPDGAFDHLVGLTKLNLGKNS 184
Query: 234 --NVIPKV-------AFLRLNHNKLSDEGLPSRGFD-VSSILDLQLSHNQLTKVPRISAH 283
++ P+V LRL N+L+D +P FD + ++ +L L NQ+ + H
Sbjct: 185 LTHISPRVFQHLGNLQVLRLYENRLTD--IPMGTFDGLVNLQELALQQNQIGLLSPGLFH 242
Query: 284 ----LQHLHLDHNKIKSVNVSVICPSP----------SMLPAERDSFSYGPHLRYLRLDG 329
LQ L+L +N I + S+ P S+ F P+LR L L
Sbjct: 243 NNHNLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSLGIFGPMPNLRELWLYD 302
Query: 330 NEIKPPIPMALMTCFRLLQAVII 352
N I +P + + R LQ +I+
Sbjct: 303 NHIS-SLPDNVFSNLRQLQVLIL 324
Score = 58.5 bits (140), Expect = 9e-09
Identities = 42/133 (31%), Positives = 70/133 (52%), Gaps = 7/133 (5%)
Query: 76 LYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEE 135
L+L +N I ++P+ F N QL+ + L++N+I+ I GA + L +L L L N L++
Sbjct: 298 LWLYDNHISSLPDNVFSNLRQLQVLILSRNQISF--ISPGAFNGLTELRELSLHTNALQD 355
Query: 136 VPSPLPRSLEQLQ---LARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLK 192
+ + R L LQ L N++ ++P F+N+ L + LQNN+L + F L
Sbjct: 356 LDGNVFRMLANLQNISLQNNRLRQLPGNIFANVNGLMAIQLQNNQLEN--LPLGIFDHLG 413
Query: 193 NLMQLNMAKNALR 205
L +L + N R
Sbjct: 414 KLCELRLYDNPWR 426
>gi|194440719 chondroadherin-like [Homo sapiens]
Length = 762
Score = 89.4 bits (220), Expect = 5e-18
Identities = 80/256 (31%), Positives = 117/256 (45%), Gaps = 16/256 (6%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIP-AIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C S + C + L E+P AIP L LQ NL++ IP F+ L +
Sbjct: 33 CPQACICDNS-RRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHL 91
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPL---PRSLEQLQLARNKVSRI 157
+L ++ + +GA L +LL L L N L E+P SL +L+L N + +
Sbjct: 92 DLRHCEVEL--VAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEEL 149
Query: 158 PQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPR----LPA 213
GTF L L L+L +N LV F+GL + L ++ NAL + P LPA
Sbjct: 150 RPGTFGALGALATLNLAHNALV--YLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPA 207
Query: 214 NTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQ 273
+L L +N ++ +P + +A L L HN L+ G G + + +L L
Sbjct: 208 -LRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAG-EEDGLALPGLRELLLDGGA 265
Query: 274 LTKV-PRISAHLQHLH 288
L + PR AH LH
Sbjct: 266 LQALGPRAFAHCPRLH 281
Score = 76.6 bits (187), Expect = 3e-14
Identities = 70/233 (30%), Positives = 109/233 (46%), Gaps = 24/233 (10%)
Query: 133 LEEVPSPLPRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLK 192
L EVP +P ++L L N + IP F + +LT LDL++ ++ F+GL
Sbjct: 53 LTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEV--ELVAEGAFRGLG 110
Query: 193 NLMQLNMAKNALRNMPPRL---PANTMQLFLDNNSIEGIPENYFNVIPKVAFLRLNHNKL 249
L+ LN+A N LR +P + +L L+ N++E + F + +A L L HN L
Sbjct: 111 RLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNAL 170
Query: 250 SDEGLPSRGFD-VSSILDLQLSHNQLTKV-PRISA---HLQHLHLDHNKIKSVNVSVICP 304
LP+ F + + L+LSHN L+ + P A L+ L L HN+++++ V+
Sbjct: 171 --VYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQ 228
Query: 305 -----------SPSMLPAERDSFSYGPHLRYLRLDGNEIKPPIPMALMTCFRL 346
+P E D + P LR L LDG ++ P A C RL
Sbjct: 229 ARGLARLELGHNPLTYAGEEDGLAL-PGLRELLLDGGALQALGPRAFAHCPRL 280
Score = 68.9 bits (167), Expect = 6e-12
Identities = 87/312 (27%), Positives = 134/312 (42%), Gaps = 61/312 (19%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIP-AIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP C C P + CE GL+ +P PS L L+ N ++P F L +
Sbjct: 396 CPRACVCVPESRHSS-CEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSL 454
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSP----LPRSLEQLQLARNKVSR 156
+L I +E GAL+ L +L++L+L DN+L + + PR L L L RN+ +
Sbjct: 455 HLQHCGIAE--LEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPR-LGYLYLERNRFLQ 511
Query: 157 IPQGTFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALR--NMPPRLPAN 214
+P L +L L LQ+N VD D + + L + ++ N + ++ PA
Sbjct: 512 VPGAALRALPSLFSLHLQDN-AVDRLAPGDLGR-TRALRWVYLSGNRITEVSLGALGPAR 569
Query: 215 TMQ-LFLDNNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQ 273
++ L LD N + +P EGLP ++L+LQLS N
Sbjct: 570 ELEKLHLDRNQLREVPTGAL------------------EGLP-------ALLELQLSGNP 604
Query: 274 LTKV-----PRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFS-YGPHLRYLRL 327
L + + LQHL L+ S + ICP +FS GP L+ L L
Sbjct: 605 LRALRDGAFQPVGRSLQHLFLN-----SSGLEQICPG---------AFSGLGPGLQSLHL 650
Query: 328 DGNEIK--PPIP 337
N+++ P +P
Sbjct: 651 QKNQLRALPALP 662
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/180 (27%), Positives = 74/180 (41%), Gaps = 30/180 (16%)
Query: 72 RIWYLYLQNNLIETIPEKPFENATQLRWINLNKNKITNYGIEKGALSQLKKLLFLFLEDN 131
R+ YLYL+ N +P L ++L N + + G L + + L +++L N
Sbjct: 498 RLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDR--LAPGDLGRTRALRWVYLSGN 555
Query: 132 ELEEVPSPL---PRSLEQLQLARNKVSRIPQGTFSNLENLTLLDLQNN---KLVDNAFQ- 184
+ EV R LE+L L RN++ +P G L L L L N L D AFQ
Sbjct: 556 RITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQP 615
Query: 185 -------------------RDTFKGL-KNLMQLNMAKNALRNMPPRLPANTMQLFLDNNS 224
F GL L L++ KN LR + P LP+ + +D +S
Sbjct: 616 VGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRAL-PALPSLSQLELIDLSS 674
>gi|7662102 leucine rich repeat transmembrane neuronal 2 [Homo
sapiens]
Length = 516
Score = 86.7 bits (213), Expect = 3e-17
Identities = 81/299 (27%), Positives = 140/299 (46%), Gaps = 51/299 (17%)
Query: 42 CPMECFCPPSFPTALYCENRGLKEIP-AIPSRIWYLYLQNNLIETIPEKPFENATQLRWI 100
CP +C C YC+++G +P A L L++N I + F + +QL W+
Sbjct: 34 CPPKCRCEKLL---FYCDSQGFHSVPNATDKGSLGLSLRHNHITELERDQFASFSQLTWL 90
Query: 101 NLNKNKITNYGIEKGALSQLKKLLFLFLEDNELEEVPSPLPRSLEQLQLARNKVSRIPQG 160
+L+ N+I+ +++ A L K L++L L+ NK+ +P
Sbjct: 91 HLDHNQIST--VKEDAFQGLYK---------------------LKELILSSNKIFYLPNT 127
Query: 161 TFSNLENLTLLDLQNNKLVDNAFQRDTFKGLKNLMQLNMAKNALRNMPPRLPANTMQL-F 219
TF+ L NL LDL N+L ++ + F GL+ L L++ N+LR +P RL + L F
Sbjct: 128 TFTQLINLQNLDLSFNQL--SSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWDCRSLEF 185
Query: 220 LD--NNSIEGIPENYFNVIPKVAFLRLNHNKLSDEGLPSRGFDVSSILDLQLSHNQLTK- 276
LD N + + N F + K+ L L HN+L+ + +SS+ L L N+++
Sbjct: 186 LDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINF-AHFLRLSSLHTLFLQWNKISNL 244
Query: 277 ---VPRISAHLQHLHLDHNKIKSVNVSVICPSPSMLPAERDSFSYGPHLRYLRLDGNEI 332
+ L+ L L N+IK+++++V F P+L+ L +D N++
Sbjct: 245 TCGMEWTWGTLEKLDLTGNEIKAIDLTV--------------FETMPNLKILLMDNNKL 289
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,969,627
Number of Sequences: 37866
Number of extensions: 637162
Number of successful extensions: 3743
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 174
Number of HSP's successfully gapped in prelim test: 102
Number of HSP's that attempted gapping in prelim test: 1583
Number of HSP's gapped (non-prelim): 913
length of query: 352
length of database: 18,247,518
effective HSP length: 103
effective length of query: 249
effective length of database: 14,347,320
effective search space: 3572482680
effective search space used: 3572482680
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.