Guide to the Human Genome
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Search of human proteins with 58533167

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo
sapiens]
         (210 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo s...   447   e-126
gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo s...   443   e-125
gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Ho...   443   e-125
gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo s...   427   e-120
gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo s...   427   e-120
gi|4505881 plasminogen [Homo sapiens]                                 132   3e-31
gi|205277383 macrophage stimulating 1 (hepatocyte growth factor-...   128   4e-30
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]                99   2e-21
gi|4503635 coagulation factor II preproprotein [Homo sapiens]          97   8e-21
gi|19743898 receptor tyrosine kinase-like orphan receptor 2 prec...    93   1e-19
gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]         93   2e-19
gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]         93   2e-19
gi|134152686 receptor tyrosine kinase-like orphan receptor 1 iso...    88   6e-18
gi|134152725 receptor tyrosine kinase-like orphan receptor 1 iso...    87   8e-18
gi|4505861 plasminogen activator, tissue isoform 1 preproprotein...    70   2e-12
gi|14702169 plasminogen activator, tissue isoform 3 preproprotei...    70   2e-12
gi|145275213 coagulation factor XII precursor [Homo sapiens]           55   3e-08
gi|4758502 hyaluronan binding protein 2 preproprotein [Homo sapi...    55   4e-08
gi|24041012 kringle-containing transmembrane protein 1 isoform 2...    51   8e-07
gi|227116325 kringle-containing transmembrane protein 1 isoform ...    51   8e-07
gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo ...    50   2e-06
gi|4504383 HGF activator preproprotein [Homo sapiens]                  49   3e-06
gi|222537759 plasminogen activator, urokinase isoform 2 [Homo sa...    48   5e-06
gi|4505863 plasminogen activator, urokinase isoform 1 preproprot...    48   5e-06
gi|13375642 kringle-containing transmembrane protein 2 isoform b...    42   3e-04
gi|27437008 kringle-containing transmembrane protein 2 isoform d...    42   3e-04
gi|4506143 neurotrypsin precursor [Homo sapiens]                       39   0.002
gi|209571507 HGFL protein isoform 2 [Homo sapiens]                     38   0.007
gi|51317358 HGFL protein isoform 1 [Homo sapiens]                      38   0.007
gi|74048573 plasminogen-like B1 [Homo sapiens]                         33   0.13 

>gi|58533167 hepatocyte growth factor isoform 5 precursor [Homo
           sapiens]
          Length = 210

 Score =  447 bits (1150), Expect = e-126
 Identities = 210/210 (100%), Positives = 210/210 (100%)

Query: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
           MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60

Query: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
           TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120

Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
           NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180

Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210


>gi|58533163 hepatocyte growth factor isoform 2 precursor [Homo
           sapiens]
          Length = 290

 Score =  443 bits (1139), Expect = e-125
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
           MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60

Query: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
           TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120

Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
           NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180

Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
           RGEEGGPWCFTSNPEVRYEVCDIPQCSE
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208



 Score = 85.1 bits (209), Expect = 4e-17
 Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 1/79 (1%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C+   G SY+G +  T+SG  CQ W    PH H FLP  Y  K   +NYCRNP G+   P
Sbjct: 211 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP-RP 269

Query: 188 WCFTSNPEVRYEVCDIPQC 206
           WC+T +P  R+E C I  C
Sbjct: 270 WCYTLDPHTRWEYCAIKTC 288


>gi|33859835 hepatocyte growth factor isoform 1 preproprotein [Homo
           sapiens]
          Length = 728

 Score =  443 bits (1139), Expect = e-125
 Identities = 208/208 (100%), Positives = 208/208 (100%)

Query: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
           MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60

Query: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
           TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120

Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
           NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180

Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
           RGEEGGPWCFTSNPEVRYEVCDIPQCSE
Sbjct: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208



 Score = 97.8 bits (242), Expect = 6e-21
 Identities = 42/80 (52%), Positives = 53/80 (66%), Gaps = 2/80 (2%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           CI G+G  Y+GTV+   +GI CQ W S  PHEH   P +++ KDL+ENYCRNP G E  P
Sbjct: 305 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSE-SP 363

Query: 188 WCFTSNPEVRYEVC-DIPQC 206
           WCFT++P +R   C  IP C
Sbjct: 364 WCFTTDPNIRVGYCSQIPNC 383



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 36/81 (44%), Positives = 47/81 (58%), Gaps = 1/81 (1%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C+   G SY+G +  T+SG  CQ W    PH H FLP  Y  K   +NYCRNP G+   P
Sbjct: 211 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP-RP 269

Query: 188 WCFTSNPEVRYEVCDIPQCSE 208
           WC+T +P  R+E C I  C++
Sbjct: 270 WCYTLDPHTRWEYCAIKTCAD 290



 Score = 74.7 bits (182), Expect = 5e-14
 Identities = 30/81 (37%), Positives = 45/81 (55%)

Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEG 185
           ++C  G G++Y G +S T+SG+ C  W   +   H  +        L ENYCRNP  +  
Sbjct: 389 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 448

Query: 186 GPWCFTSNPEVRYEVCDIPQC 206
           GPWC+T NP + ++ C I +C
Sbjct: 449 GPWCYTGNPLIPWDYCPISRC 469


>gi|58533165 hepatocyte growth factor isoform 4 precursor [Homo
           sapiens]
          Length = 285

 Score =  427 bits (1098), Expect = e-120
 Identities = 203/208 (97%), Positives = 203/208 (97%), Gaps = 5/208 (2%)

Query: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
           MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60

Query: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
           TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120

Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
           NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH     SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175

Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
           RGEEGGPWCFTSNPEVRYEVCDIPQCSE
Sbjct: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 203



 Score = 85.1 bits (209), Expect = 4e-17
 Identities = 36/79 (45%), Positives = 45/79 (56%), Gaps = 1/79 (1%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C+   G SY+G +  T+SG  CQ W    PH H FLP  Y  K   +NYCRNP G+   P
Sbjct: 206 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP-RP 264

Query: 188 WCFTSNPEVRYEVCDIPQC 206
           WC+T +P  R+E C I  C
Sbjct: 265 WCYTLDPHTRWEYCAIKTC 283


>gi|58533170 hepatocyte growth factor isoform 3 precursor [Homo
           sapiens]
          Length = 723

 Score =  427 bits (1098), Expect = e-120
 Identities = 203/208 (97%), Positives = 203/208 (97%), Gaps = 5/208 (2%)

Query: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60
           MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK
Sbjct: 1   MWVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIK 60

Query: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120
           TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE
Sbjct: 61  TKKVNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYE 120

Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
           NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH     SYRGKDLQENYCRNP
Sbjct: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEH-----SYRGKDLQENYCRNP 175

Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
           RGEEGGPWCFTSNPEVRYEVCDIPQCSE
Sbjct: 176 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 203



 Score = 97.8 bits (242), Expect = 6e-21
 Identities = 42/80 (52%), Positives = 53/80 (66%), Gaps = 2/80 (2%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           CI G+G  Y+GTV+   +GI CQ W S  PHEH   P +++ KDL+ENYCRNP G E  P
Sbjct: 300 CIQGQGEGYRGTVNTIWNGIPCQRWDSQYPHEHDMTPENFKCKDLRENYCRNPDGSE-SP 358

Query: 188 WCFTSNPEVRYEVC-DIPQC 206
           WCFT++P +R   C  IP C
Sbjct: 359 WCFTTDPNIRVGYCSQIPNC 378



 Score = 86.3 bits (212), Expect = 2e-17
 Identities = 36/81 (44%), Positives = 47/81 (58%), Gaps = 1/81 (1%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C+   G SY+G +  T+SG  CQ W    PH H FLP  Y  K   +NYCRNP G+   P
Sbjct: 206 CMTCNGESYRGLMDHTESGKICQRWDHQTPHRHKFLPERYPDKGFDDNYCRNPDGQP-RP 264

Query: 188 WCFTSNPEVRYEVCDIPQCSE 208
           WC+T +P  R+E C I  C++
Sbjct: 265 WCYTLDPHTRWEYCAIKTCAD 285



 Score = 74.7 bits (182), Expect = 5e-14
 Identities = 30/81 (37%), Positives = 45/81 (55%)

Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEG 185
           ++C  G G++Y G +S T+SG+ C  W   +   H  +        L ENYCRNP  +  
Sbjct: 384 QDCYRGNGKNYMGNLSQTRSGLTCSMWDKNMEDLHRHIFWEPDASKLNENYCRNPDDDAH 443

Query: 186 GPWCFTSNPEVRYEVCDIPQC 206
           GPWC+T NP + ++ C I +C
Sbjct: 444 GPWCYTGNPLIPWDYCPISRC 464


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  132 bits (331), Expect = 3e-31
 Identities = 62/151 (41%), Positives = 93/151 (61%), Gaps = 7/151 (4%)

Query: 61  TKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFD 117
           TKK     + ++CA +C  ++   FTC+AF +    +QC+    N  SS + +    +  
Sbjct: 37  TKKQLGAGSIEECAAKCEEDE--EFTCRAFQYHSKEQQCVIMAENRKSSIIIRM--RDVV 92

Query: 118 LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYC 177
           L+E K Y+  C  G G++Y+GT+S TK+GI CQ WSS  PH   F P+++  + L+ENYC
Sbjct: 93  LFEKKVYLSECKTGNGKNYRGTMSKTKNGITCQKWSSTSPHRPRFSPATHPSEGLEENYC 152

Query: 178 RNPRGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
           RNP  +  GPWC+T++PE RY+ CDI +C E
Sbjct: 153 RNPDNDPQGPWCYTTDPEKRYDYCDILECEE 183



 Score =  100 bits (249), Expect = 9e-22
 Identities = 42/83 (50%), Positives = 57/83 (68%), Gaps = 1/83 (1%)

Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
           +++C  G G+SY+GT S T +G KCQ WSSM PH H   P +Y    L  NYCRNP  ++
Sbjct: 374 VQDCYHGDGQSYRGTSSTTTTGKKCQSWSSMTPHRHQKTPENYPNAGLTMNYCRNPDADK 433

Query: 185 GGPWCFTSNPEVRYEVCDIPQCS 207
            GPWCFT++P VR+E C++ +CS
Sbjct: 434 -GPWCFTTDPSVRWEYCNLKKCS 455



 Score = 98.2 bits (243), Expect = 4e-21
 Identities = 38/82 (46%), Positives = 55/82 (67%), Gaps = 1/82 (1%)

Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-FLPSSYRGKDLQENYCRNPRGEEG 185
           +C+ G G+ Y+G  + T +G  CQ W++  PH HS F P +     L++NYCRNP G+ G
Sbjct: 480 DCMFGNGKGYRGKRATTVTGTPCQDWAAQEPHRHSIFTPETNPRAGLEKNYCRNPDGDVG 539

Query: 186 GPWCFTSNPEVRYEVCDIPQCS 207
           GPWC+T+NP   Y+ CD+PQC+
Sbjct: 540 GPWCYTTNPRKLYDYCDVPQCA 561



 Score = 97.4 bits (241), Expect = 8e-21
 Identities = 39/80 (48%), Positives = 56/80 (70%), Gaps = 1/80 (1%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C+   G +Y G +S T SG++CQ W S  PH H ++PS +  K+L++NYCRNP   E  P
Sbjct: 185 CMHCSGENYDGKISKTMSGLECQAWDSQSPHAHGYIPSKFPNKNLKKNYCRNP-DRELRP 243

Query: 188 WCFTSNPEVRYEVCDIPQCS 207
           WCFT++P  R+E+CDIP+C+
Sbjct: 244 WCFTTDPNKRWELCDIPRCT 263



 Score = 94.7 bits (234), Expect = 5e-20
 Identities = 39/79 (49%), Positives = 53/79 (67%), Gaps = 1/79 (1%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C+ G G +Y+G V++T SG  CQ WS+  PH H+  P ++  K+L ENYCRNP G+   P
Sbjct: 275 CLKGTGENYRGNVAVTVSGHTCQHWSAQTPHTHNRTPENFPCKNLDENYCRNPDGKR-AP 333

Query: 188 WCFTSNPEVRYEVCDIPQC 206
           WC T+N +VR+E C IP C
Sbjct: 334 WCHTTNSQVRWEYCKIPSC 352


>gi|205277383 macrophage stimulating 1 (hepatocyte growth
           factor-like) [Homo sapiens]
          Length = 725

 Score =  128 bits (321), Expect = 4e-30
 Identities = 71/209 (33%), Positives = 110/209 (52%), Gaps = 13/209 (6%)

Query: 2   WVTKLLPALLLQHVLLHLLLLPIAIPYAEGQRKRRNTIHEFKKSAKTTLIKIDPALKIKT 61
           WVT   PA  +  + L LLL         G   +R+ +++F+    T L  +  A+    
Sbjct: 5   WVTVQPPARRMGWLPLLLLLTQCL-----GVPGQRSPLNDFQVLRGTELQHLLHAVVPGP 59

Query: 62  KKVNTAD--QCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSSGVKKEFGHEFDLY 119
            + + AD  +CA RC    G    C+AF ++ +   C   P+   S   +       DL+
Sbjct: 60  WQEDVADAEECAGRC----GPLMDCRAFHYNVSSHGCQLLPWTQHSPHTRLRRSGRCDLF 115

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           + KDY+R CI+  G  Y+GT++ T  G+ CQ WS   P++H + P+   G  L+EN+CRN
Sbjct: 116 QKKDYVRTCIMNNGVGYRGTMATTVGGLPCQAWSHKFPNDHKYTPTLRNG--LEENFCRN 173

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
           P G+ GGPWC+T++P VR++ C I  C E
Sbjct: 174 PDGDPGGPWCYTTDPAVRFQSCGIKSCRE 202



 Score = 94.4 bits (233), Expect = 6e-20
 Identities = 40/83 (48%), Positives = 53/83 (63%), Gaps = 2/83 (2%)

Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG 186
           +C  GKG  Y+GT + T +G+ CQ W + IPH+H F P  Y  KDL+EN+CRNP G E  
Sbjct: 296 SCFRGKGEGYRGTANTTTAGVPCQRWDAQIPHQHRFTPEKYACKDLRENFCRNPDGSE-A 354

Query: 187 PWCFTSNPEVRYEVC-DIPQCSE 208
           PWCFT  P +R   C  I +C++
Sbjct: 355 PWCFTLRPGMRAAFCYQIRRCTD 377



 Score = 89.4 bits (220), Expect = 2e-18
 Identities = 35/79 (44%), Positives = 50/79 (63%), Gaps = 1/79 (1%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C+   G  Y+G V  T+SG +CQ W    PH+H F P  +  + L +NYCRNP G E  P
Sbjct: 205 CVWCNGEEYRGAVDRTESGRECQRWDLQHPHQHPFEPGKFLDQGLDDNYCRNPDGSE-RP 263

Query: 188 WCFTSNPEVRYEVCDIPQC 206
           WC+T++P++  E CD+P+C
Sbjct: 264 WCYTTDPQIEREFCDLPRC 282



 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 34/83 (40%), Positives = 54/83 (65%)

Query: 126 RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEG 185
           ++C  G G  Y+GTVS T+ G++CQ WS+  PH+  F  +S     L+EN+CRNP G+  
Sbjct: 382 QDCYHGAGEQYRGTVSKTRKGVQCQRWSAETPHKPQFTFTSEPHAQLEENFCRNPDGDSH 441

Query: 186 GPWCFTSNPEVRYEVCDIPQCSE 208
           GPWC+T +P   ++ C + +C++
Sbjct: 442 GPWCYTMDPRTPFDYCALRRCAD 464


>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
          Length = 2040

 Score = 99.4 bits (246), Expect = 2e-21
 Identities = 42/89 (47%), Positives = 55/89 (61%), Gaps = 1/89 (1%)

Query: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
            E    +R C  G G+SY+GT S T +G  CQ WSSM PH H   P +Y    L  NYCRN
Sbjct: 1608 EQTPVVRQCYHGNGQSYRGTFSTTVTGRTCQSWSSMTPHRHQRTPENYPNDGLTMNYCRN 1667

Query: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
            P  +  GPWCFT +P +R+E C++ +CS+
Sbjct: 1668 PDADT-GPWCFTMDPSIRWEYCNLTRCSD 1695



 Score = 97.8 bits (242), Expect = 6e-21
 Identities = 44/89 (49%), Positives = 57/89 (64%), Gaps = 1/89 (1%)

Query: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
            E    +++C  G GRSY+G  S T +G  CQ WSSMIPH H   P +Y    L ENYCRN
Sbjct: 1494 EKSPVVQDCYHGDGRSYRGISSTTVTGRTCQSWSSMIPHWHQRTPENYPNAGLTENYCRN 1553

Query: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
            P   +  PWC+T++P VR+E C++ QCSE
Sbjct: 1554 PDSGK-QPWCYTTDPCVRWEYCNLTQCSE 1581



 Score = 95.5 bits (236), Expect = 3e-20
 Identities = 41/91 (45%), Positives = 58/91 (63%), Gaps = 1/91 (1%)

Query: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
            E +  ++ C  G G+SY+GT  IT +G  CQ WSSM PH HS  P+ Y    L +NYCRN
Sbjct: 932  EQRPGVQECYHGNGQSYQGTYFITVTGRTCQAWSSMTPHSHSRTPAYYPNAGLIKNYCRN 991

Query: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
            P      PWC+T++P VR+E C++ +CS+ +
Sbjct: 992  P-DPVAAPWCYTTDPSVRWEYCNLTRCSDAE 1021



 Score = 94.4 bits (233), Expect = 6e-20
 Identities = 36/83 (43%), Positives = 55/83 (66%), Gaps = 1/83 (1%)

Query: 126  RNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHS-FLPSSYRGKDLQENYCRNPRGEE 184
            ++C+ G G+ Y+G  + T +G  CQ W++  PH HS F+P + +   L++NYCRNP G+ 
Sbjct: 1718 QDCMFGNGKGYRGKKATTVTGTPCQEWAAQEPHRHSTFIPGTNKWAGLEKNYCRNPDGDI 1777

Query: 185  GGPWCFTSNPEVRYEVCDIPQCS 207
             GPWC+T NP   ++ CDIP C+
Sbjct: 1778 NGPWCYTMNPRKLFDYCDIPLCA 1800



 Score = 94.0 bits (232), Expect = 8e-20
 Identities = 42/89 (47%), Positives = 55/89 (61%), Gaps = 1/89 (1%)

Query: 118  LYENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYC 177
            L E    +++C    G+SY+GT S T +G  CQ WSSM PH+HS  P +Y    L  NYC
Sbjct: 1044 LTEETPGVQDCYYHYGQSYRGTYSTTVTGRTCQAWSSMTPHQHSRTPENYPNAGLTRNYC 1103

Query: 178  RNPRGEEGGPWCFTSNPEVRYEVCDIPQC 206
            RNP  E   PWC+T +P VR+E C++ QC
Sbjct: 1104 RNPDAEI-RPWCYTMDPSVRWEYCNLTQC 1131



 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 41/87 (47%), Positives = 55/87 (63%), Gaps = 1/87 (1%)

Query: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
            EN   +++C  G G+SY+GT+S T +G  CQ WSSM PH H  +P  Y    L  NYCRN
Sbjct: 1380 ENSTGVQDCYRGDGQSYRGTLSTTITGRTCQSWSSMTPHWHRRIPLYYPNAGLTRNYCRN 1439

Query: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQC 206
            P  E   PWC+T +P VR+E C++ +C
Sbjct: 1440 PDAEI-RPWCYTMDPSVRWEYCNLTRC 1465



 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 818 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 877

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           P      P+C+T +P VR+E C++ QCS+ +
Sbjct: 878 P-DPVAAPYCYTRDPSVRWEYCNLTQCSDAE 907



 Score = 91.3 bits (225), Expect = 5e-19
 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 134 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 193

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           P      P+C+T +P VR+E C++ QCS+ +
Sbjct: 194 P-DAVAAPYCYTRDPGVRWEYCNLTQCSDAE 223



 Score = 91.3 bits (225), Expect = 5e-19
 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 248 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 307

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           P      P+C+T +P VR+E C++ QCS+ +
Sbjct: 308 P-DAVAAPYCYTRDPGVRWEYCNLTQCSDAE 337



 Score = 91.3 bits (225), Expect = 5e-19
 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 362 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 421

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           P      P+C+T +P VR+E C++ QCS+ +
Sbjct: 422 P-DAVAAPYCYTRDPGVRWEYCNLTQCSDAE 451



 Score = 91.3 bits (225), Expect = 5e-19
 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 476 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 535

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           P      P+C+T +P VR+E C++ QCS+ +
Sbjct: 536 P-DAVAAPYCYTRDPGVRWEYCNLTQCSDAE 565



 Score = 91.3 bits (225), Expect = 5e-19
 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 590 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 649

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           P      P+C+T +P VR+E C++ QCS+ +
Sbjct: 650 P-DAVAAPYCYTRDPGVRWEYCNLTQCSDAE 679



 Score = 91.3 bits (225), Expect = 5e-19
 Identities = 41/91 (45%), Positives = 55/91 (60%), Gaps = 1/91 (1%)

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           E +  ++ C  G G+SY+GT S T +G  CQ WSSM PH HS  P  Y    L  NYCRN
Sbjct: 704 EQRPGVQECYHGNGQSYRGTYSTTVTGRTCQAWSSMTPHSHSRTPEYYPNAGLIMNYCRN 763

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           P      P+C+T +P VR+E C++ QCS+ +
Sbjct: 764 P-DAVAAPYCYTRDPGVRWEYCNLTQCSDAE 793



 Score = 89.0 bits (219), Expect = 3e-18
 Identities = 39/91 (42%), Positives = 56/91 (61%), Gaps = 1/91 (1%)

Query: 120 ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
           E    +++C  G G+SY+GT S T +G  CQ WSSM PH+H+    +Y    L  NYCRN
Sbjct: 20  EQSHVVQDCYHGDGQSYRGTYSTTVTGRTCQAWSSMTPHQHNRTTENYPNAGLIMNYCRN 79

Query: 180 PRGEEGGPWCFTSNPEVRYEVCDIPQCSEGK 210
           P      P+C+T +P VR+E C++ QCS+ +
Sbjct: 80  P-DAVAAPYCYTRDPGVRWEYCNLTQCSDAE 109



 Score = 87.4 bits (215), Expect = 8e-18
 Identities = 39/87 (44%), Positives = 51/87 (58%), Gaps = 1/87 (1%)

Query: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
            E    +++C  G G+SY+G+ S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 1160 EQSPGVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1219

Query: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQC 206
            P  E   PWC+T +P VR+E C++ QC
Sbjct: 1220 PDAEI-SPWCYTMDPNVRWEYCNLTQC 1245



 Score = 87.0 bits (214), Expect = 1e-17
 Identities = 39/87 (44%), Positives = 51/87 (58%), Gaps = 1/87 (1%)

Query: 120  ENKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRN 179
            E    +++C  G G+SY+G+ S T +G  CQ WSSM PH H      Y    L  NYCRN
Sbjct: 1266 EQSPTVQDCYHGDGQSYRGSFSTTVTGRTCQSWSSMTPHWHQRTTEYYPNGGLTRNYCRN 1325

Query: 180  PRGEEGGPWCFTSNPEVRYEVCDIPQC 206
            P  E   PWC+T +P VR+E C++ QC
Sbjct: 1326 PDAEI-RPWCYTMDPSVRWEYCNLTQC 1351


>gi|4503635 coagulation factor II preproprotein [Homo sapiens]
          Length = 622

 Score = 97.4 bits (241), Expect = 8e-21
 Identities = 40/82 (48%), Positives = 55/82 (67%)

Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG 186
           NC  G G +Y+G V+IT+SGI+CQ W S  PH+     +++ G DLQEN+CRNP     G
Sbjct: 107 NCAEGLGTNYRGHVNITRSGIECQLWRSRYPHKPEINSTTHPGADLQENFCRNPDSSTTG 166

Query: 187 PWCFTSNPEVRYEVCDIPQCSE 208
           PWC+T++P VR + C IP C +
Sbjct: 167 PWCYTTDPTVRRQECSIPVCGQ 188



 Score = 62.4 bits (150), Expect = 3e-10
 Identities = 26/84 (30%), Positives = 42/84 (50%)

Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
           +  C+  +G+ Y+G +++T  G+ C  W+S      S          L EN+CRNP G+E
Sbjct: 210 LEQCVPDRGQQYQGRLAVTTHGLPCLAWASAQAKALSKHQDFNSAVQLVENFCRNPDGDE 269

Query: 185 GGPWCFTSNPEVRYEVCDIPQCSE 208
            G WC+ +     +  CD+  C E
Sbjct: 270 EGVWCYVAGKPGDFGYCDLNYCEE 293


>gi|19743898 receptor tyrosine kinase-like orphan receptor 2
           precursor [Homo sapiens]
          Length = 943

 Score = 93.2 bits (230), Expect = 1e-19
 Identities = 39/80 (48%), Positives = 47/80 (58%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C  G G  Y+GT S TKSG +CQPW+   PH H    + +        YCRNP G+  GP
Sbjct: 316 CYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQMEGP 375

Query: 188 WCFTSNPEVRYEVCDIPQCS 207
           WCFT N  VR E+CD+P CS
Sbjct: 376 WCFTQNKNVRMELCDVPSCS 395


>gi|22035663 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
          Length = 132

 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 39/84 (46%), Positives = 53/84 (63%), Gaps = 1/84 (1%)

Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
           ++ C    G+SY+GT   T +G  CQ WSSM PH+HS  P  Y    L  NYCRNP    
Sbjct: 25  VQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNP-DCS 83

Query: 185 GGPWCFTSNPEVRYEVCDIPQCSE 208
            GPWC+T++P VR+E C++ +CS+
Sbjct: 84  AGPWCYTTDPNVRWEYCNLTRCSD 107


>gi|13346502 lipoprotein, Lp(a)-like 2 precursor [Homo sapiens]
          Length = 132

 Score = 92.8 bits (229), Expect = 2e-19
 Identities = 39/84 (46%), Positives = 53/84 (63%), Gaps = 1/84 (1%)

Query: 125 IRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEE 184
           ++ C    G+SY+GT   T +G  CQ WSSM PH+HS  P  Y    L  NYCRNP    
Sbjct: 25  VQECYHSNGQSYRGTYFTTVTGRTCQAWSSMTPHQHSRTPEKYPNDGLISNYCRNP-DCS 83

Query: 185 GGPWCFTSNPEVRYEVCDIPQCSE 208
            GPWC+T++P VR+E C++ +CS+
Sbjct: 84  AGPWCYTTDPNVRWEYCNLTRCSD 107


>gi|134152686 receptor tyrosine kinase-like orphan receptor 1
           isoform 2 [Homo sapiens]
          Length = 393

 Score = 87.8 bits (216), Expect = 6e-18
 Identities = 37/88 (42%), Positives = 54/88 (61%), Gaps = 2/88 (2%)

Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
           NK++   C    G  Y+GTVS+TKSG +CQPW+S  PH H+F    +   +   +YCRNP
Sbjct: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365

Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQCSE 208
             ++  PWCFT +   + ++CDIP C +
Sbjct: 366 GNQKEAPWCFTLDENFKSDLCDIPACGK 393


>gi|134152725 receptor tyrosine kinase-like orphan receptor 1
           isoform 1 [Homo sapiens]
          Length = 937

 Score = 87.4 bits (215), Expect = 8e-18
 Identities = 37/86 (43%), Positives = 53/86 (61%), Gaps = 2/86 (2%)

Query: 121 NKDYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNP 180
           NK++   C    G  Y+GTVS+TKSG +CQPW+S  PH H+F    +   +   +YCRNP
Sbjct: 308 NKNH--KCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHSYCRNP 365

Query: 181 RGEEGGPWCFTSNPEVRYEVCDIPQC 206
             ++  PWCFT +   + ++CDIP C
Sbjct: 366 GNQKEAPWCFTLDENFKSDLCDIPAC 391


>gi|4505861 plasminogen activator, tissue isoform 1 preproprotein
           [Homo sapiens]
          Length = 562

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 5/85 (5%)

Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDL---QENYCRNPRGE 183
           +C  G G +Y+GT S+T+SG  C PW+SMI     +   +   + L   + NYCRNP G 
Sbjct: 214 DCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG- 272

Query: 184 EGGPWCFT-SNPEVRYEVCDIPQCS 207
           +  PWC    N  + +E CD+P CS
Sbjct: 273 DAKPWCHVLKNRRLTWEYCDVPSCS 297



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSF---LPSSYRGKDLQENYCRNPRGEE 184
           C   +G SY+GT S  +SG +C  W+S    +  +    P + R      NYCRNP   +
Sbjct: 127 CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNP-DRD 185

Query: 185 GGPWCFTSNP-EVRYEVCDIPQCSEG 209
             PWC+     +   E C  P CSEG
Sbjct: 186 SKPWCYVFKAGKYSSEFCSTPACSEG 211


>gi|14702169 plasminogen activator, tissue isoform 3 preproprotein
           [Homo sapiens]
          Length = 516

 Score = 69.7 bits (169), Expect = 2e-12
 Identities = 34/85 (40%), Positives = 48/85 (56%), Gaps = 5/85 (5%)

Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDL---QENYCRNPRGE 183
           +C  G G +Y+GT S+T+SG  C PW+SMI     +   +   + L   + NYCRNP G 
Sbjct: 168 DCYFGNGSAYRGTHSLTESGASCLPWNSMILIGKVYTAQNPSAQALGLGKHNYCRNPDG- 226

Query: 184 EGGPWCFT-SNPEVRYEVCDIPQCS 207
           +  PWC    N  + +E CD+P CS
Sbjct: 227 DAKPWCHVLKNRRLTWEYCDVPSCS 251



 Score = 52.4 bits (124), Expect = 3e-07
 Identities = 30/86 (34%), Positives = 41/86 (47%), Gaps = 5/86 (5%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSF---LPSSYRGKDLQENYCRNPRGEE 184
           C   +G SY+GT S  +SG +C  W+S    +  +    P + R      NYCRNP   +
Sbjct: 81  CYEDQGISYRGTWSTAESGAECTNWNSSALAQKPYSGRRPDAIRLGLGNHNYCRNP-DRD 139

Query: 185 GGPWCFTSNP-EVRYEVCDIPQCSEG 209
             PWC+     +   E C  P CSEG
Sbjct: 140 SKPWCYVFKAGKYSSEFCSTPACSEG 165


>gi|145275213 coagulation factor XII precursor [Homo sapiens]
          Length = 615

 Score = 55.5 bits (132), Expect = 3e-08
 Identities = 28/81 (34%), Positives = 41/81 (50%), Gaps = 2/81 (2%)

Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGG 186
           +C  G+G SY+G    T SG  CQPW+S   + +     +         +CRNP   +  
Sbjct: 216 SCYDGRGLSYRGLARTTLSGAPCQPWASEATYRNVTAEQARNWGLGGHAFCRNP-DNDIR 274

Query: 187 PWCFTSNPE-VRYEVCDIPQC 206
           PWCF  N + + +E CD+ QC
Sbjct: 275 PWCFVLNRDRLSWEYCDLAQC 295


>gi|4758502 hyaluronan binding protein 2 preproprotein [Homo
           sapiens]
          Length = 560

 Score = 55.1 bits (131), Expect = 4e-08
 Identities = 28/86 (32%), Positives = 48/86 (55%), Gaps = 6/86 (6%)

Query: 127 NCIIGKGRSYKGTVSITKSGIKCQPWSSMI---PHEHSFLPSSYRGKDLQENYCRNPRGE 183
           +C +G G SY+G ++ T +   C  W+S +    + + F+  +      + N+CRNP  +
Sbjct: 193 DCYVGDGYSYRGKMNRTVNQHACLYWNSHLLLQENYNMFMEDAETHGIGEHNFCRNPDAD 252

Query: 184 EGGPWCF--TSNPEVRYEVCDIPQCS 207
           E  PWCF   +N +V++E CD+  CS
Sbjct: 253 E-KPWCFIKVTNDKVKWEYCDVSACS 277


>gi|24041012 kringle-containing transmembrane protein 1 isoform 2
           precursor [Homo sapiens]
          Length = 492

 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 8/85 (9%)

Query: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSFL--PSSYRGKDLQENYCRNPRGE 183
           C    G  Y+GT + T  + G  C  W+    H ++ L  P+   G   + NYCRNP G+
Sbjct: 34  CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG-EHNYCRNPDGD 92

Query: 184 EGGPWCFTSNPE--VRYEVCDIPQC 206
              PWC+ +  E  V ++ C+IP C
Sbjct: 93  V-SPWCYVAEHEDGVYWKYCEIPAC 116


>gi|227116325 kringle-containing transmembrane protein 1 isoform 3
           precursor [Homo sapiens]
          Length = 458

 Score = 50.8 bits (120), Expect = 8e-07
 Identities = 29/85 (34%), Positives = 43/85 (50%), Gaps = 8/85 (9%)

Query: 128 CIIGKGRSYKGTVSIT--KSGIKCQPWSSMIPHEHSFL--PSSYRGKDLQENYCRNPRGE 183
           C    G  Y+GT + T  + G  C  W+    H ++ L  P+   G   + NYCRNP G+
Sbjct: 34  CFTANGADYRGTQNWTALQGGKPCLFWNETFQHPYNTLKYPNGEGGLG-EHNYCRNPDGD 92

Query: 184 EGGPWCFTSNPE--VRYEVCDIPQC 206
              PWC+ +  E  V ++ C+IP C
Sbjct: 93  V-SPWCYVAEHEDGVYWKYCEIPAC 116


>gi|239743017 PREDICTED: hypothetical protein XP_002342719 [Homo
           sapiens]
          Length = 299

 Score = 49.7 bits (117), Expect = 2e-06
 Identities = 17/32 (53%), Positives = 22/32 (68%)

Query: 176 YCRNPRGEEGGPWCFTSNPEVRYEVCDIPQCS 207
           YCRNP G+  GPWC+  NP   ++ CDIP C+
Sbjct: 7   YCRNPDGDINGPWCYRVNPRKLFDYCDIPLCA 38


>gi|4504383 HGF activator preproprotein [Homo sapiens]
          Length = 655

 Score = 48.9 bits (115), Expect = 3e-06
 Identities = 25/83 (30%), Positives = 40/83 (48%), Gaps = 5/83 (6%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDL---QENYCRNPRGEE 184
           C +G G  Y+G  S + SG+ C  W+S + ++   + S      L      YCRNP  +E
Sbjct: 286 CFLGNGTGYRGVASTSASGLSCLAWNSDLLYQELHVDSVGAAALLGLGPHAYCRNPDNDE 345

Query: 185 GGPWCF-TSNPEVRYEVCDIPQC 206
             PWC+   +  + +E C +  C
Sbjct: 346 -RPWCYVVKDSALSWEYCRLEAC 367


>gi|222537759 plasminogen activator, urokinase isoform 2 [Homo
           sapiens]
          Length = 414

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 9/94 (9%)

Query: 123 DYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQ-----ENYC 177
           D  + C  G G  Y+G  S    G  C PW+S    + ++   ++R   LQ      NYC
Sbjct: 48  DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTY--HAHRSDALQLGLGKHNYC 105

Query: 178 RNPRGEEGGPWCFTS-NPEVRYEVCDIPQCSEGK 210
           RNP      PWC+     +   + C +  C++GK
Sbjct: 106 RNPDNRR-RPWCYVQVGLKPLVQECMVHDCADGK 138


>gi|4505863 plasminogen activator, urokinase isoform 1 preproprotein
           [Homo sapiens]
          Length = 431

 Score = 48.1 bits (113), Expect = 5e-06
 Identities = 28/94 (29%), Positives = 42/94 (44%), Gaps = 9/94 (9%)

Query: 123 DYIRNCIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQ-----ENYC 177
           D  + C  G G  Y+G  S    G  C PW+S    + ++   ++R   LQ      NYC
Sbjct: 65  DKSKTCYEGNGHFYRGKASTDTMGRPCLPWNSATVLQQTY--HAHRSDALQLGLGKHNYC 122

Query: 178 RNPRGEEGGPWCFTS-NPEVRYEVCDIPQCSEGK 210
           RNP      PWC+     +   + C +  C++GK
Sbjct: 123 RNPDNRR-RPWCYVQVGLKPLVQECMVHDCADGK 155


>gi|13375642 kringle-containing transmembrane protein 2 isoform b
           precursor [Homo sapiens]
          Length = 420

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 7/88 (7%)

Query: 125 IRNCIIGKGRSYKGTVSITK---SGIKCQPWSSMIPHEHSFLPSSYRGKDL-QENYCRNP 180
           +  C    G  Y+G  + T    +G  C  W     H +S     +    L   N+CRNP
Sbjct: 33  LSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNP 92

Query: 181 RGEEGGPWCFTSNPE--VRYEVCDIPQC 206
            G+   PWC+ +  E  + +  CDIP C
Sbjct: 93  DGDV-QPWCYVAETEEGIYWRYCDIPSC 119


>gi|27437008 kringle-containing transmembrane protein 2 isoform d
           precursor [Homo sapiens]
          Length = 462

 Score = 42.4 bits (98), Expect = 3e-04
 Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 7/88 (7%)

Query: 125 IRNCIIGKGRSYKGTVSITK---SGIKCQPWSSMIPHEHSFLPSSYRGKDL-QENYCRNP 180
           +  C    G  Y+G  + T    +G  C  W     H +S     +    L   N+CRNP
Sbjct: 33  LSECFQVNGADYRGHQNRTGPRGAGRPCLFWDQTQQHSYSSASDPHGRWGLGAHNFCRNP 92

Query: 181 RGEEGGPWCFTSNPE--VRYEVCDIPQC 206
            G+   PWC+ +  E  + +  CDIP C
Sbjct: 93  DGDV-QPWCYVAETEEGIYWRYCDIPSC 119


>gi|4506143 neurotrypsin precursor [Homo sapiens]
          Length = 875

 Score = 39.3 bits (90), Expect = 0.002
 Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 8/68 (11%)

Query: 140 VSITKSGIKCQPWSSMIPHEHSFLPSSY---RGKDLQENYCRNPRGEEGGPWCF--TSNP 194
           VS+T  G  C  W+ + P      P+S+   RG+  + N+CR+P G  G PWCF   +  
Sbjct: 100 VSVTDFGAPCLRWAEVPPFLERSPPASWAQLRGQ--RHNFCRSPDG-AGRPWCFYGDARG 156

Query: 195 EVRYEVCD 202
           +V +  CD
Sbjct: 157 KVDWGYCD 164


>gi|209571507 HGFL protein isoform 2 [Homo sapiens]
          Length = 173

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C    G  Y+   +    G++C  W        S L S+        +YCRNP  +  GP
Sbjct: 25  CFWDNGHLYREDQTSPAPGLRCLNWLDA----QSGLASAPVSGAGNHSYCRNPDEDPRGP 80

Query: 188 WCFTSN----PEVRYEVCDIPQCSE 208
           WC+ S     PE R   C+  +C E
Sbjct: 81  WCYVSGEAGVPEKR--PCEDLRCPE 103


>gi|51317358 HGFL protein isoform 1 [Homo sapiens]
          Length = 263

 Score = 37.7 bits (86), Expect = 0.007
 Identities = 25/85 (29%), Positives = 35/85 (41%), Gaps = 10/85 (11%)

Query: 128 CIIGKGRSYKGTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP 187
           C    G  Y+   +    G++C  W        S L S+        +YCRNP  +  GP
Sbjct: 25  CFWDNGHLYREDQTSPAPGLRCLNWLDA----QSGLASAPVSGAGNHSYCRNPDEDPRGP 80

Query: 188 WCFTSN----PEVRYEVCDIPQCSE 208
           WC+ S     PE R   C+  +C E
Sbjct: 81  WCYVSGEAGVPEKR--PCEDLRCPE 103


>gi|74048573 plasminogen-like B1 [Homo sapiens]
          Length = 96

 Score = 33.5 bits (75), Expect = 0.13
 Identities = 19/55 (34%), Positives = 29/55 (52%), Gaps = 5/55 (9%)

Query: 55  PALKIKTKK---VNTADQCANRCTRNKGLPFTCKAFVFDKARKQCLWFPFNSMSS 106
           P+L   TKK     + ++CA +C  +K   FTC+AF +    +QC+    N  SS
Sbjct: 31  PSLFSVTKKQLGAGSREECAAKCEEDK--EFTCRAFQYHSKEQQCVIMAENRKSS 83


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.137    0.442 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,691,867
Number of Sequences: 37866
Number of extensions: 397457
Number of successful extensions: 853
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 745
Number of HSP's gapped (non-prelim): 74
length of query: 210
length of database: 18,247,518
effective HSP length: 98
effective length of query: 112
effective length of database: 14,536,650
effective search space: 1628104800
effective search space used: 1628104800
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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