Guide to the Human Genome
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Name: HGF Sequence: fasta or formatted (285aa) NCBI GI: 58533165
Description:

hepatocyte growth factor isoform 4 precursor

Referenced in:

Coagulation
Liver
Receptor Tyrosine Kinases

Other entries for this name:
alt prot [728aa] hepatocyte growth factor isoform 1 preproprotein
alt prot [290aa] hepatocyte growth factor isoform 2 precursor
alt prot [210aa] hepatocyte growth factor isoform 5 precursor
alt prot [723aa] hepatocyte growth factor isoform 3 precursor
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.5         10           1
 C cysteine            6.0         17           1
 D aspartate           4.9         14           2
 E glutamate           6.3         18           2
 F phenylalanine       3.9         11           1
 G glycine             6.0         17           2
 H histidine           3.9         11           1
 I isoleucine          5.3         15           2
 K lysine              9.1         26           2
 L leucine             7.0         20           4
 M methionine          1.8          5           1
 N asparagine          4.6         13           1
 P proline             6.7         19           1
 Q glutamine           3.5         10           1
 R arginine            6.7         19           2
 S serine              4.9         14           2
 T threonine           6.3         18           2
 V valine              3.2          9           1
 W tryptophan          2.5          7           1
 Y tyrosine            4.2         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hepatocyte growth factor isoform 4 precursor 
HGF                   0.993   hepatocyte growth factor isoform 3 precursor 
HGF                   0.990   hepatocyte growth factor isoform 2 precursor 
HGF                   0.983   hepatocyte growth factor isoform 1 preproprotein [Ho...
HGF                   0.668   hepatocyte growth factor isoform 5 precursor 
MST1                  0.354   macrophage stimulating 1 (hepatocyte growth factor-...
PLG                   0.329   plasminogen 
LPA                   0.252   lipoprotein Lp(a) precursor 
F2                    0.150   coagulation factor II preproprotein 
LPAL2                 0.135   lipoprotein, Lp(a)-like 2 precursor 
LPAL2                 0.135   lipoprotein, Lp(a)-like 2 precursor 
PLAT                  0.131   plasminogen activator, tissue isoform 1 preproprotein...
PLAT                  0.131   plasminogen activator, tissue isoform 3 preproprotei...
ROR2                  0.115   receptor tyrosine kinase-like orphan receptor 2 prec...
ROR1                  0.100   receptor tyrosine kinase-like orphan receptor 1 iso...
ROR1                  0.100   receptor tyrosine kinase-like orphan receptor 1 iso...
KREMEN1               0.071   kringle-containing transmembrane protein 1 isoform 2...
KREMEN1               0.071   kringle-containing transmembrane protein 1 isoform ...
F12                   0.065   coagulation factor XII precursor 
KREMEN2               0.060   kringle-containing transmembrane protein 2 isoform b...
KREMEN2               0.060   kringle-containing transmembrane protein 2 isoform d...
HGFAC                 0.056   HGF activator preproprotein 
HABP2                 0.053   hyaluronan binding protein 2 preproprotein 
LOC100289195          0.042   PREDICTED: hypothetical protein XP_002342719 
PLAU                  0.035   plasminogen activator, urokinase isoform 2 
PLAU                  0.035   plasminogen activator, urokinase isoform 1 preproprot...
PRSS12                0.035   neurotrypsin precursor 
PIK3IP1               0.020   HGFL protein isoform 2 
PIK3IP1               0.020   HGFL protein isoform 1 
ADAMTS18              0.017   ADAM metallopeptidase with thrombospondin type 1 mot...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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