Search of human proteins with 58331209

Search of human proteins with 58331209

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|58331209 chymotrypsin-like elastase family, member 1 [Homo
sapiens]
         (258 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|58331209 chymotrypsin-like elastase family, member 1 [Homo sa...   535   e-152
gi|15559207 elastase 2A preproprotein [Homo sapiens]                  295   3e-80
gi|58331211 elastase 2B preproprotein [Homo sapiens]                  285   4e-77
gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens]       279   2e-75
gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]     278   4e-75
gi|62526043 chymotrypsin C preproprotein [Homo sapiens]               254   7e-68
gi|4503137 chymotrypsin-like [Homo sapiens]                           170   1e-42
gi|4505881 plasminogen [Homo sapiens]                                 156   1e-38
gi|4503627 coagulation factor XI precursor [Homo sapiens]             154   6e-38
gi|32698940 transmembrane protease, serine 12 [Homo sapiens]          154   7e-38
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             154   1e-37
gi|118498350 chymotrypsin B2 [Homo sapiens]                           153   1e-37
gi|68508970 tryptase beta 2 precursor [Homo sapiens]                  152   2e-37
gi|118498341 chymotrypsin B1 [Homo sapiens]                           151   5e-37
gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]            151   6e-37
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         151   6e-37
gi|33695155 hepsin [Homo sapiens]                                     148   5e-36
gi|4504481 hepsin [Homo sapiens]                                      148   5e-36
gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]           146   2e-35
gi|110815798 ovochymase 1 [Homo sapiens]                              146   2e-35
gi|4503649 coagulation factor IX preproprotein [Homo sapiens]         143   2e-34
gi|148613878 acrosin precursor [Homo sapiens]                         142   2e-34
gi|117956391 protease, serine, 33 [Homo sapiens]                      140   1e-33
gi|13994276 marapsin [Homo sapiens]                                   139   2e-33
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   139   2e-33
gi|4503549 neutrophil elastase preproprotein [Homo sapiens]           139   3e-33
gi|4506153 prostasin preproprotein [Homo sapiens]                     138   4e-33
gi|148231605 ovochymase 2 [Homo sapiens]                              138   5e-33
gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]           137   7e-33
gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]       137   7e-33

>gi|58331209 chymotrypsin-like elastase family, member 1 [Homo
           sapiens]
          Length = 258

 Score =  535 bits (1379), Expect = e-152
 Identities = 258/258 (100%), Positives = 258/258 (100%)

Query: 1   MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT 60
           MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT
Sbjct: 1   MLVLYGHSTQDLPETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMT 60

Query: 61  AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS 120
           AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS
Sbjct: 61  AAHCVDYQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQS 120

Query: 121 VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS 180
           VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS
Sbjct: 121 VTLNSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSS 180

Query: 181 YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV 240
           YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV
Sbjct: 181 YWGSTVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTV 240

Query: 241 FTQVSAYISWINNVIASN 258
           FTQVSAYISWINNVIASN
Sbjct: 241 FTQVSAYISWINNVIASN 258


>gi|15559207 elastase 2A preproprotein [Homo sapiens]
          Length = 269

 Score =  295 bits (755), Expect = 3e-80
 Identities = 142/247 (57%), Positives = 174/247 (70%), Gaps = 1/247 (0%)

Query: 13  PETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFR 72
           P    RVVGG EA  NSWP Q+SLQY S G  YHTCGG+LI  +WV+TAAHC+   +T+R
Sbjct: 23  PPYVTRVVGGEEARPNSWPWQVSLQYSSNGKWYHTCGGSLIANSWVLTAAHCISSSRTYR 82

Query: 73  VVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVL 132
           V  G HNL   +     VSV KIVVH  WNS+ ++ G DIALL+LA  V+L   +QL  L
Sbjct: 83  VGLGRHNLYVAESGSLAVSVSKIVVHKDWNSNQISKGNDIALLKLANPVSLTDKIQLACL 142

Query: 133 PQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVC 192
           P  G IL NN PCY+TGWG+ +TNG +   LQQ  L  VDYA CSSS++WGS+VK +M+C
Sbjct: 143 PPAGTILPNNYPCYVTGWGRLQTNGAVPDVLQQGRLLVVDYATCSSSAWWGSSVKTSMIC 202

Query: 193 AGGDGVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWI 251
           AGGDGV S C GDSGGPL+C   +G++ VHG+ SF S  GCN   KP+VFT+VS YI WI
Sbjct: 203 AGGDGVISSCNGDSGGPLNCQASDGRWQVHGIVSFGSRLGCNYYHKPSVFTRVSNYIDWI 262

Query: 252 NNVIASN 258
           N+VIA+N
Sbjct: 263 NSVIANN 269


>gi|58331211 elastase 2B preproprotein [Homo sapiens]
          Length = 269

 Score =  285 bits (728), Expect = 4e-77
 Identities = 137/243 (56%), Positives = 168/243 (69%), Gaps = 1/243 (0%)

Query: 17  ARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAG 76
           +R++GG EA  NSWP Q+SLQY S G  YHTCGG+LI  +WV+TAAHC+     +RV+ G
Sbjct: 27  SRMLGGEEARPNSWPWQVSLQYSSNGQWYHTCGGSLIANSWVLTAAHCISSSGIYRVMLG 86

Query: 77  DHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEG 136
            HNL   +     VSV KIVVH  WNSD V+ G DIALL+LA  V+L   +QL  LP  G
Sbjct: 87  QHNLYVAESGSLAVSVSKIVVHKDWNSDQVSKGNDIALLKLANPVSLTDKIQLACLPPAG 146

Query: 137 AILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGD 196
            IL NN PCY+TGWG+ +TNG L   L+Q  L  VDYA CSSS +WGSTVK  M+CAGGD
Sbjct: 147 TILPNNYPCYVTGWGRLQTNGALPDDLKQGRLLVVDYATCSSSGWWGSTVKTNMICAGGD 206

Query: 197 GVRSGCQGDSGGPLHCLV-NGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVI 255
           GV   C GDSGGPL+C   +G++ VHG+ S  S  GCN   KP++FT+VS Y  WIN+VI
Sbjct: 207 GVICTCNGDSGGPLNCQASDGRWEVHGIGSLTSVLGCNYYYKPSIFTRVSNYNDWINSVI 266

Query: 256 ASN 258
           A+N
Sbjct: 267 ANN 269


>gi|6679625 elastase 3B, pancreatic preproprotein [Homo sapiens]
          Length = 270

 Score =  279 bits (714), Expect = 2e-75
 Identities = 136/246 (55%), Positives = 173/246 (70%), Gaps = 4/246 (1%)

Query: 16  NARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVA 75
           ++RVV G +A   SWP Q+SLQY   GS YHTCGG+LI  +WV+TA HC+   +T++VV 
Sbjct: 26  SSRVVNGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISSSRTYQVVL 85

Query: 76  GDHNLSQNDGTEQYVSVQK--IVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLP 133
           G+++ +  +G EQ + +    + VHP WN   VA G DIAL++L++S  L   VQL  LP
Sbjct: 86  GEYDRAVKEGPEQVIPINSGDLFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASLP 145

Query: 134 QEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCA 193
             G IL N +PCYITGWG+  TNG L   LQ+A LP VDY  CS  ++WGS+VK TMVCA
Sbjct: 146 PAGDILPNETPCYITGWGRLYTNGPLPDKLQEALLPVVDYEHCSRWNWWGSSVKKTMVCA 205

Query: 194 GGDGVRSGCQGDSGGPLHC-LVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWIN 252
           GGD +RSGC GDSGGPL+C   +G + VHGVTSFVS+ GCN  RKPTVFT+VSA+I WI 
Sbjct: 206 GGD-IRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNTRRKPTVFTRVSAFIDWIE 264

Query: 253 NVIASN 258
             IAS+
Sbjct: 265 ETIASH 270


>gi|236460050 elastase 3A, pancreatic preproprotein [Homo sapiens]
          Length = 270

 Score =  278 bits (710), Expect = 4e-75
 Identities = 138/247 (55%), Positives = 174/247 (70%), Gaps = 4/247 (1%)

Query: 15  TNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVV 74
           +++RVV G +A   SWP Q+SLQY   GS YHTCGG+LI  +WV+TA HC+    T++VV
Sbjct: 25  SSSRVVHGEDAVPYSWPWQVSLQYEKSGSFYHTCGGSLIAPDWVVTAGHCISRDLTYQVV 84

Query: 75  AGDHNLSQNDGTEQYVSV--QKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVL 132
            G++NL+  +G EQ + +  +++ VHP WN   VA G DIAL++L++S  L   VQL  L
Sbjct: 85  LGEYNLAVKEGPEQVIPINSEELFVHPLWNRSCVACGNDIALIKLSRSAQLGDAVQLASL 144

Query: 133 PQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVC 192
           P  G IL N +PCYITGWG+  TNG L   LQQA LP VDY  CS  ++WGSTVK TMVC
Sbjct: 145 PPAGDILPNKTPCYITGWGRLYTNGPLPDKLQQARLPVVDYKHCSRWNWWGSTVKKTMVC 204

Query: 193 AGGDGVRSGCQGDSGGPLHC-LVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWI 251
           AGG  +RSGC GDSGGPL+C   +G + VHGVTSFVS+ GCN   KPTVFT+VSA+I WI
Sbjct: 205 AGG-YIRSGCNGDSGGPLNCPTEDGGWQVHGVTSFVSAFGCNFIWKPTVFTRVSAFIDWI 263

Query: 252 NNVIASN 258
              IAS+
Sbjct: 264 EETIASH 270


>gi|62526043 chymotrypsin C preproprotein [Homo sapiens]
          Length = 268

 Score =  254 bits (648), Expect = 7e-68
 Identities = 126/242 (52%), Positives = 161/242 (66%), Gaps = 4/242 (1%)

Query: 13  PETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFR 72
           P  +ARVVGG +A  +SWP QISLQY    +  HTCGGTLI  N+V+TAAHC+   +T+R
Sbjct: 24  PNLSARVVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYR 83

Query: 73  VVAGDHNLSQNDGTEQ-YVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGV 131
           V  G +NL   D     +V V  I VH  WN+  +    DIAL++LA+ V L+  +Q+  
Sbjct: 84  VAVGKNNLEVEDEEGSLFVGVDTIHVHKRWNA--LLLRNDIALIKLAEHVELSDTIQVAC 141

Query: 132 LPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMV 191
           LP++ ++L  + PCY+TGWG+  TNG +A  LQQ   P VD+A CS   +WG  VK TMV
Sbjct: 142 LPEKDSLLPKDYPCYVTGWGRLWTNGPIADKLQQGLQPVVDHATCSRIDWWGFRVKKTMV 201

Query: 192 CAGGDGVRSGCQGDSGGPLHC-LVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISW 250
           CAGGDGV S C GDSGGPL+C L NG + V G+ SF S RGCN  +KP V+T+VSAYI W
Sbjct: 202 CAGGDGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVSAYIDW 261

Query: 251 IN 252
           IN
Sbjct: 262 IN 263


>gi|4503137 chymotrypsin-like [Homo sapiens]
          Length = 264

 Score =  170 bits (431), Expect = 1e-42
 Identities = 99/242 (40%), Positives = 133/242 (54%), Gaps = 11/242 (4%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGD 77
           R+V G  A   SWP Q+SLQ  SG   +H CGG+LI Q+WV+TAAHC        VV G+
Sbjct: 33  RIVNGENAVLGSWPWQVSLQDSSG---FHFCGGSLISQSWVVTAAHCNVSPGRHFVVLGE 89

Query: 78  HNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGA 137
           ++ S N    Q +SV + + HP WNS  +    D+ LL+LA      + +    L     
Sbjct: 90  YDRSSNAEPLQVLSVSRAITHPSWNSTTM--NNDVTLLKLASPAQYTTRISPVCLASSNE 147

Query: 138 ILANNSPCYITGWGKTKTNGQLAQT-LQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGGD 196
            L     C  TGWG+    G +    LQQ  LP V    C    YWGS++ ++M+CAGG 
Sbjct: 148 ALTEGLTCVTTGWGRLSGVGNVTPAHLQQVALPLVTVNQC--RQYWGSSITDSMICAGGA 205

Query: 197 GVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVIA 256
           G  S CQGDSGGPL C     + + G+ S+  ++ CNV R P V+T+VS + +WIN VIA
Sbjct: 206 GA-SSCQGDSGGPLVCQKGNTWVLIGIVSW-GTKNCNV-RAPAVYTRVSKFSTWINQVIA 262

Query: 257 SN 258
            N
Sbjct: 263 YN 264


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  156 bits (395), Expect = 1e-38
 Identities = 92/246 (37%), Positives = 136/246 (55%), Gaps = 20/246 (8%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQ---KTFRVV 74
           RVVGG  A  +SWP Q+SL+ R G    H CGGTLI   WV+TAAHC++      +++V+
Sbjct: 580 RVVGGCVAHPHSWPWQVSLRTRFG---MHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVI 636

Query: 75  AGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQ 134
            G H     +   Q + V ++ + P           DIALL+L+    +   V    LP 
Sbjct: 637 LGAHQEVNLEPHVQEIEVSRLFLEP--------TRKDIALLKLSSPAVITDKVIPACLPS 688

Query: 135 EGAILANNSPCYITGWGKTK-TNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCA 193
              ++A+ + C+ITGWG+T+ T G  A  L++A LP ++  +C+   +    V++T +CA
Sbjct: 689 PNYVVADRTECFITGWGETQGTFG--AGLLKEAQLPVIENKVCNRYEFLNGRVQSTELCA 746

Query: 194 GG-DGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWIN 252
           G   G    CQGDSGGPL C    KY + GVTS+    GC    KP V+ +VS +++WI 
Sbjct: 747 GHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSW--GLGCARPNKPGVYVRVSRFVTWIE 804

Query: 253 NVIASN 258
            V+ +N
Sbjct: 805 GVMRNN 810


>gi|4503627 coagulation factor XI precursor [Homo sapiens]
          Length = 625

 Score =  154 bits (390), Expect = 6e-38
 Identities = 88/238 (36%), Positives = 129/238 (54%), Gaps = 10/238 (4%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHC---VDYQKTFRVV 74
           R+VGGT + R  WP Q++L   S   R H CGG++I   W++TAAHC   V+  K  RV 
Sbjct: 387 RIVGGTASVRGEWPWQVTLHTTSPTQR-HLCGGSIIGNQWILTAAHCFYGVESPKILRVY 445

Query: 75  AGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQ 134
           +G  N S+      +  VQ+I++H  +      +GYDIALL+L  +V      +   LP 
Sbjct: 446 SGILNQSEIKEDTSFFGVQEIIIHDQYKM--AESGYDIALLKLETTVNYTDSQRPICLPS 503

Query: 135 EGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG 194
           +G      + C++TGWG  K   ++  TLQ+A +P V    C    Y G  + + M+CAG
Sbjct: 504 KGDRNVIYTDCWVTGWGYRKLRDKIQNTLQKAKIPLVTNEEC-QKRYRGHKITHKMICAG 562

Query: 195 -GDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWI 251
             +G +  C+GDSGGPL C  N  + + G+TS+    GC    +P V+T V  Y+ WI
Sbjct: 563 YREGGKDACKGDSGGPLSCKHNEVWHLVGITSW--GEGCAQRERPGVYTNVVEYVDWI 618


>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
          Length = 348

 Score =  154 bits (389), Expect = 7e-38
 Identities = 87/242 (35%), Positives = 130/242 (53%), Gaps = 11/242 (4%)

Query: 17  ARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQK---TFRV 73
           +R++GGTEA   +WP  +SLQ + G    H CGGTL+R+ WV+TAAHC         +  
Sbjct: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTA 135

Query: 74  VAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLP 133
           V G +N+       + + ++ I++HP +  ++     DIAL  L ++V  N Y+Q   LP
Sbjct: 136 VIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYV--NDIALFHLKKAVRYNDYIQPICLP 193

Query: 134 QE-GAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVC 192
            +   IL  N+ C+I+GWG+TK  G     LQ A +  +   +C+S   +G  + NT  C
Sbjct: 194 FDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFC 253

Query: 193 AGG-DGVRSGCQGDSGGPLHCLV--NGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYIS 249
           AG  DG    C+GDSGGPL C +    ++ V G+TS+    GC     P V+   S Y  
Sbjct: 254 AGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSY--GHGCGRRGFPGVYIGPSFYQK 311

Query: 250 WI 251
           W+
Sbjct: 312 WL 313


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  154 bits (388), Expect = 1e-37
 Identities = 85/242 (35%), Positives = 131/242 (54%), Gaps = 10/242 (4%)

Query: 14  ETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKT 70
           +T+ R+VGGT +    WP Q+SLQ +    R H CGG+LI   WV+TAAHC D    Q  
Sbjct: 386 KTSTRIVGGTNSSWGEWPWQVSLQVKLTAQR-HLCGGSLIGHQWVLTAAHCFDGLPLQDV 444

Query: 71  FRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLG 130
           +R+ +G  NLS       +  +++I++H  +        +DIAL++L   +    + +  
Sbjct: 445 WRIYSGILNLSDITKDTPFSQIKEIIIHQNYKVSE--GNHDIALIKLQAPLNYTEFQKPI 502

Query: 131 VLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTM 190
            LP +G      + C++TGWG +K  G++   LQ+  +P V    C    Y    +   M
Sbjct: 503 CLPSKGDTSTIYTNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRM 561

Query: 191 VCAG-GDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYIS 249
           VCAG  +G +  C+GDSGGPL C  NG + + G+TS+    GC    +P V+T+V+ Y+ 
Sbjct: 562 VCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSW--GEGCARREQPGVYTKVAEYMD 619

Query: 250 WI 251
           WI
Sbjct: 620 WI 621


>gi|118498350 chymotrypsin B2 [Homo sapiens]
          Length = 263

 Score =  153 bits (387), Expect = 1e-37
 Identities = 90/243 (37%), Positives = 137/243 (56%), Gaps = 12/243 (4%)

Query: 17  ARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAG 76
           +R+V G +A   SWP Q+SLQ ++G   +H CGG+LI ++WV+TAAHC   + +  VVAG
Sbjct: 32  SRIVNGEDAVPGSWPWQVSLQDKTG---FHFCGGSLISEDWVVTAAHC-GVRTSDVVVAG 87

Query: 77  DHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEG 136
           + +   ++   Q + + K+  +P ++   +    DI LL+LA     +  V    LP   
Sbjct: 88  EFDQGSDEENIQVLKIAKVFKNPKFSI--LTVNNDITLLKLATPARFSQTVSAVCLPSAD 145

Query: 137 AILANNSPCYITGWGKTKTN-GQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGG 195
                 + C  TGWGKTK N  +    LQQA LP +  A C  S  WG  + + M+CAG 
Sbjct: 146 DDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKS--WGRRITDVMICAGA 203

Query: 196 DGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVI 255
            GV S C GDSGGPL C  +G +++ G+ S+  SR C+ +  P V+ +V+  I W+  ++
Sbjct: 204 SGV-SSCMGDSGGPLVCQKDGAWTLVGIVSW-GSRTCSTT-TPAVYARVAKLIPWVQKIL 260

Query: 256 ASN 258
           A+N
Sbjct: 261 AAN 263


>gi|68508970 tryptase beta 2 precursor [Homo sapiens]
          Length = 275

 Score =  152 bits (385), Expect = 2e-37
 Identities = 93/252 (36%), Positives = 136/252 (53%), Gaps = 26/252 (10%)

Query: 19  VVGGTEAGRNSWPSQISLQYRSGGSRY--HTCGGTLIRQNWVMTAAHCVDYQ----KTFR 72
           +VGG EA R+ WP Q+SL+ R    RY  H CGG+LI   WV+TAAHCV          R
Sbjct: 31  IVGGQEAPRSKWPWQVSLRVRD---RYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALR 87

Query: 73  VVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVL 132
           V   + +L   D   Q + V +I+VHP + +  + A  DIALL L + V ++S+V    L
Sbjct: 88  VQLREQHLYYQD---QLLPVSRIIVHPQFYTAQIGA--DIALLELEEPVNVSSHVHTVTL 142

Query: 133 PQEGAILANNSPCYITGWGKTKTNGQLAQ--TLQQAYLPSVDYAICSSSSYWGS------ 184
           P          PC++TGWG    + +L     L+Q  +P ++  IC +  + G+      
Sbjct: 143 PPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDV 202

Query: 185 -TVKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQ 243
             V++ M+CAG    R  CQGDSGGPL C VNG +   GV S+    GC    +P ++T+
Sbjct: 203 RIVRDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSW--GEGCAQPNRPGIYTR 259

Query: 244 VSAYISWINNVI 255
           V+ Y+ WI++ +
Sbjct: 260 VTYYLDWIHHYV 271


>gi|118498341 chymotrypsin B1 [Homo sapiens]
          Length = 263

 Score =  151 bits (382), Expect = 5e-37
 Identities = 90/243 (37%), Positives = 136/243 (55%), Gaps = 12/243 (4%)

Query: 17  ARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAG 76
           +R+V G +A   SWP Q+SLQ ++G   +H CGG+LI ++WV+TAAHC   + +  VVAG
Sbjct: 32  SRIVNGEDAVPGSWPWQVSLQDKTG---FHFCGGSLISEDWVVTAAHC-GVRTSDVVVAG 87

Query: 77  DHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEG 136
           + +   ++   Q + + K+  +P ++   +    DI LL+LA     +  V    LP   
Sbjct: 88  EFDQGSDEENIQVLKIAKVFKNPKFSI--LTVNNDITLLKLATPARFSQTVSAVCLPSAD 145

Query: 137 AILANNSPCYITGWGKTKTN-GQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGG 195
                 + C  TGWGKTK N  +    LQQA LP +  A C  S  WG  + + M+CAG 
Sbjct: 146 DDFPAGTLCATTGWGKTKYNANKTPDKLQQAALPLLSNAECKKS--WGRRITDVMICAGA 203

Query: 196 DGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVI 255
            GV S C GDSGGPL C  +G +++ G+ S+  S  C+ S  P V+ +V+  I W+  ++
Sbjct: 204 SGV-SSCMGDSGGPLVCQKDGAWTLVGIVSW-GSDTCSTS-SPGVYARVTKLIPWVQKIL 260

Query: 256 ASN 258
           A+N
Sbjct: 261 AAN 263


>gi|13775595 tryptase alpha/beta 1 precursor [Homo sapiens]
          Length = 275

 Score =  151 bits (381), Expect = 6e-37
 Identities = 91/250 (36%), Positives = 134/250 (53%), Gaps = 22/250 (8%)

Query: 19  VVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQ----KTFRVV 74
           +VGG EA R+ WP Q+SL+   G    H CGG+LI   WV+TAAHCV          RV 
Sbjct: 31  IVGGQEAPRSKWPWQVSLRVH-GPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQ 89

Query: 75  AGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQ 134
             + +L   D   Q + V +I+VHP + +  + A  DIALL L + V ++S+V    LP 
Sbjct: 90  LREQHLYYQD---QLLPVSRIIVHPQFYTAQIGA--DIALLELEEPVNVSSHVHTVTLPP 144

Query: 135 EGAILANNSPCYITGWGKTKTNGQLAQ--TLQQAYLPSVDYAICSSSSYWGS-------T 185
                    PC++TGWG    + +L     L+Q  +P ++  IC +  + G+        
Sbjct: 145 ASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRI 204

Query: 186 VKNTMVCAGGDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVS 245
           V++ M+CAG    R  CQGDSGGPL C VNG +   GV S+    GC    +P ++T+V+
Sbjct: 205 VRDDMLCAGNTR-RDSCQGDSGGPLVCKVNGTWLQAGVVSW--GEGCAQPNRPGIYTRVT 261

Query: 246 AYISWINNVI 255
            Y+ WI++ +
Sbjct: 262 YYLDWIHHYV 271


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  151 bits (381), Expect = 6e-37
 Identities = 90/247 (36%), Positives = 141/247 (57%), Gaps = 18/247 (7%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHC--VDYQKT---FR 72
           R+VGG  A  + WP Q+SL + +     H CGGTLI   WV+TAAHC  V  +K    ++
Sbjct: 325 RIVGGALASDSKWPWQVSLHFGTT----HICGGTLIDAQWVLTAAHCFFVTREKVLEGWK 380

Query: 73  VVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVL 132
           V AG  NL Q     +  S+ +I+++  +  +     YDIAL+RL++ +TL++++    L
Sbjct: 381 VYAGTSNLHQ---LPEAASIAEIIINSNYTDEE--DDYDIALMRLSKPLTLSAHIHPACL 435

Query: 133 PQEGAILANNSPCYITGWGKTK-TNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMV 191
           P  G   + N  C+ITG+GKT+ T+ + +  L++  +  +D+  C+    + S +   M+
Sbjct: 436 PMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMM 495

Query: 192 CAGG-DGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISW 250
           CAG   G R  CQGDSGGPL C  N ++ + GVTS+    GC    KP V+T+V+  + W
Sbjct: 496 CAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSW--GTGCGQRNKPGVYTKVTEVLPW 553

Query: 251 INNVIAS 257
           I + + S
Sbjct: 554 IYSKMES 560


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  148 bits (373), Expect = 5e-36
 Identities = 87/254 (34%), Positives = 136/254 (53%), Gaps = 21/254 (8%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKT----FRV 73
           R+VGG +     WP Q+SL+Y       H CGG+L+  +WV+TAAHC   +      +RV
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRV 217

Query: 74  VAGDHNLSQNDGTEQYVSVQKIVVH----PYWNSDNVAAGYDIALLRLAQSVTLNSYVQL 129
            AG    +   G +  + VQ +V H    P+ + ++     DIAL+ L+  + L  Y+Q 
Sbjct: 218 FAGAVAQASPHGLQ--LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 275

Query: 130 GVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNT 189
             LP  G  L +   C +TGWG T+  GQ A  LQ+A +P +   +C+ + ++G+ +K  
Sbjct: 276 VCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPK 335

Query: 190 MVCAG-GDGVRSGCQGDSGGPLHC----LVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQV 244
           M CAG  +G    CQGDSGGP  C        ++ + G+ S+    GC +++KP V+T+V
Sbjct: 336 MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSW--GTGCALAQKPGVYTKV 393

Query: 245 SAYISWINNVIASN 258
           S +  WI   I ++
Sbjct: 394 SDFREWIFQAIKTH 407


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  148 bits (373), Expect = 5e-36
 Identities = 87/254 (34%), Positives = 136/254 (53%), Gaps = 21/254 (8%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKT----FRV 73
           R+VGG +     WP Q+SL+Y       H CGG+L+  +WV+TAAHC   +      +RV
Sbjct: 162 RIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLLSGDWVLTAAHCFPERNRVLSRWRV 217

Query: 74  VAGDHNLSQNDGTEQYVSVQKIVVH----PYWNSDNVAAGYDIALLRLAQSVTLNSYVQL 129
            AG    +   G +  + VQ +V H    P+ + ++     DIAL+ L+  + L  Y+Q 
Sbjct: 218 FAGAVAQASPHGLQ--LGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 275

Query: 130 GVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNT 189
             LP  G  L +   C +TGWG T+  GQ A  LQ+A +P +   +C+ + ++G+ +K  
Sbjct: 276 VCLPAAGQALVDGKICTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPK 335

Query: 190 MVCAG-GDGVRSGCQGDSGGPLHC----LVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQV 244
           M CAG  +G    CQGDSGGP  C        ++ + G+ S+    GC +++KP V+T+V
Sbjct: 336 MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSW--GTGCALAQKPGVYTKV 393

Query: 245 SAYISWINNVIASN 258
           S +  WI   I ++
Sbjct: 394 SDFREWIFQAIKTH 407


>gi|4506145 protease, serine, 1 preproprotein [Homo sapiens]
          Length = 247

 Score =  146 bits (368), Expect = 2e-35
 Identities = 93/243 (38%), Positives = 131/243 (53%), Gaps = 21/243 (8%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGD 77
           ++VGG     NS P Q+SL      S YH CGG+LI + WV++A HC  Y+   +V  G+
Sbjct: 23  KIVGGYNCEENSVPYQVSLN-----SGYHFCGGSLINEQWVVSAGHC--YKSRIQVRLGE 75

Query: 78  HNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGA 137
           HN+   +G EQ+++  KI+ HP +  D      DI L++L+    +N+ V    LP   A
Sbjct: 76  HNIEVLEGNEQFINAAKIIRHPQY--DRKTLNNDIMLIKLSSRAVINARVSTISLPT--A 131

Query: 138 ILANNSPCYITGWGKTKTNG-QLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGG- 195
             A  + C I+GWG T ++G      LQ    P +  A C  +SY G    N M C G  
Sbjct: 132 PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKC-EASYPGKITSN-MFCVGFL 189

Query: 196 DGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVI 255
           +G +  CQGDSGGP+ C  NG+  + GV S+    GC    KP V+T+V  Y+ WI N I
Sbjct: 190 EGGKDSCQGDSGGPVVC--NGQ--LQGVVSW--GDGCAQKNKPGVYTKVYNYVKWIKNTI 243

Query: 256 ASN 258
           A+N
Sbjct: 244 AAN 246


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  146 bits (368), Expect = 2e-35
 Identities = 84/246 (34%), Positives = 133/246 (54%), Gaps = 16/246 (6%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQK---TFRVV 74
           R+ GG EA  + WP Q+ L++       + CGG +I   W++TAAHCV  +    ++ ++
Sbjct: 574 RIAGGEEACPHCWPWQVGLRFLGD----YQCGGAIINPVWILTAAHCVQLKNNPLSWTII 629

Query: 75  AGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQ 134
           AGDH+ +  + TEQ    + I+VH  +N+  ++   DIAL++L+  +  NS V+   LP 
Sbjct: 630 AGDHDRNLKESTEQVRRAKHIIVHEDFNT--LSYDSDIALIQLSSPLEYNSVVRPVCLPH 687

Query: 135 EGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWG--STVKNTMVC 192
               L ++  C +TGWG    +G LA  LQQ  +  ++  +C  + Y      +   M+C
Sbjct: 688 SAEPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYSAHPGGITEKMIC 747

Query: 193 AG--GDGVRSGCQGDSGGPLHCL-VNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYIS 249
           AG    G +  CQGDSGGPL C   NG + ++G+ S+    GC    KP VF +V  ++ 
Sbjct: 748 AGFAASGEKDFCQGDSGGPLVCRHENGPFVLYGIVSW--GAGCVQPWKPGVFARVMIFLD 805

Query: 250 WINNVI 255
           WI + I
Sbjct: 806 WIQSKI 811



 Score =  117 bits (294), Expect = 8e-27
 Identities = 87/260 (33%), Positives = 128/260 (49%), Gaps = 26/260 (10%)

Query: 13  PETNARVVGGTEAGRNSW----PSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD-- 66
           P   +R      + RNS     P Q+SL+       +H CGG+LI+++ V+TAAHC+D  
Sbjct: 37  PAVGSRFFSRISSWRNSTVTGHPWQVSLK----SDEHHFCGGSLIQEDRVVTAAHCLDSL 92

Query: 67  ---YQKTFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTL 123
                K   V +G+++L Q D  EQ + V KI+ HP +NS    +  DIALL L   V  
Sbjct: 93  SEKQLKNITVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSP-DIALLYLKHKVKF 151

Query: 124 NSYVQLGVLPQEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSS--SSY 181
            + VQ   LP     +     C  +GWGK     + +  LQ+  LP +D   C++   S 
Sbjct: 152 GNAVQPICLPDSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSM 211

Query: 182 WGSTVKNTMVCAG-GDGVRSGCQGDSGGPLHCLVNGK-YSVHGVTSFVSS--------RG 231
               +  TM+CAG  D     CQGDSGGPL C   G  + + G+TS+V+         R 
Sbjct: 212 NLPPLGRTMLCAGFPDWGMDACQGDSGGPLVCRRGGGIWILAGITSWVAGCAGGSVPVRN 271

Query: 232 CNVSRKPTVFTQVSAYISWI 251
            +V     +F++VS  + +I
Sbjct: 272 NHVKASLGIFSKVSELMDFI 291


>gi|4503649 coagulation factor IX preproprotein [Homo sapiens]
          Length = 461

 Score =  143 bits (360), Expect = 2e-34
 Identities = 88/237 (37%), Positives = 131/237 (55%), Gaps = 11/237 (4%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGD 77
           RVVGG +A    +P Q+ L     G     CGG+++ + W++TAAHCV+      VVAG+
Sbjct: 226 RVVGGEDAKPGQFPWQVVLN----GKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGE 281

Query: 78  HNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYV-QLGVLPQEG 136
           HN+ + + TEQ  +V +I+ H  +N+      +DIALL L + + LNSYV  + +  +E 
Sbjct: 282 HNIEETEHTEQKRNVIRIIPHHNYNAAINKYNHDIALLELDEPLVLNSYVTPICIADKEY 341

Query: 137 A-ILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG- 194
             I       Y++GWG+    G+ A  LQ   +P VD A C  S+ +  T+ N M CAG 
Sbjct: 342 TNIFLKFGSGYVSGWGRVFHKGRSALVLQYLRVPLVDRATCLRSTKF--TIYNNMFCAGF 399

Query: 195 GDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWI 251
            +G R  CQGDSGGP    V G   + G+ S+     C +  K  ++T+VS Y++WI
Sbjct: 400 HEGGRDSCQGDSGGPHVTEVEGTSFLTGIISW--GEECAMKGKYGIYTKVSRYVNWI 454


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score =  142 bits (359), Expect = 2e-34
 Identities = 89/262 (33%), Positives = 138/262 (52%), Gaps = 22/262 (8%)

Query: 13  PETNARVVGGTEAGRNSWPSQISLQ-YRSGGSRYHTCGGTLIRQNWVMTAAHCV------ 65
           P+   R+VGG  A   +WP  +SLQ +     RYHTCGG+L+   WV+TAAHC       
Sbjct: 37  PQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNV 96

Query: 66  -DYQKTF---RVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSV 121
            D++  F    +  G++   +    E+Y  V+KI++H  +NS     G DIAL+ +   +
Sbjct: 97  HDWRLVFGAKEITYGNNKPVKAPLQERY--VEKIIIHEKYNS--ATEGNDIALVEITPPI 152

Query: 122 TLNSYVQLGVLPQEGAILANNS-PCYITGWGKTKTNG-QLAQTLQQAYLPSVDYAICSSS 179
           +   ++  G LP   A L   S  C++ GWG  +    + +  L +A +  +D  +C+S+
Sbjct: 153 SCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNST 212

Query: 180 SYWGSTVKNTMVCAGGD-GVRSGCQGDSGGPLHC--LVNGKYSVHGVTSFVSSRGCNVSR 236
            ++   V+ T VCAG   G    CQGDSGGPL C       Y V G+TS+    GC  ++
Sbjct: 213 QWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSW--GVGCARAK 270

Query: 237 KPTVFTQVSAYISWINNVIASN 258
           +P ++T    Y++WI + I SN
Sbjct: 271 RPGIYTATWPYLNWIASKIGSN 292


>gi|117956391 protease, serine, 33 [Homo sapiens]
          Length = 280

 Score =  140 bits (353), Expect = 1e-33
 Identities = 87/252 (34%), Positives = 128/252 (50%), Gaps = 21/252 (8%)

Query: 13  PETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKT-- 70
           P  ++R+VGG +     WP Q S+Q+R      H CGG+LI   WV+TAAHC   +    
Sbjct: 31  PRMSSRIVGGRDGRDGEWPWQASIQHRGA----HVCGGSLIAPQWVLTAAHCFPRRALPA 86

Query: 71  -FRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQL 129
            +RV  G   L         V V+++++ P ++ D      D+ALL+L + V L++ VQ 
Sbjct: 87  EYRVRLGALRLGSTSPRTLSVPVRRVLLPPDYSEDGARG--DLALLQLRRPVPLSARVQP 144

Query: 130 GVLPQEGAILANNSPCYITGWGKTKTNGQLAQ--TLQQAYLPSVDYAICSSSSYWGSTVK 187
             LP  GA     +PC +TGWG  +    L +   LQ   +P +D   C    + G+ V 
Sbjct: 145 VCLPVPGARPPPGTPCRVTGWGSLRPGVPLPEWRPLQGVRVPLLDSRTCDGLYHVGADVP 204

Query: 188 NT-------MVCAG-GDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPT 239
                     +CAG   G +  CQGDSGGPL CL +G + + GV S+   +GC +  +P 
Sbjct: 205 QAERIVLPGSLCAGYPQGHKDACQGDSGGPLTCLQSGSWVLVGVVSW--GKGCALPNRPG 262

Query: 240 VFTQVSAYISWI 251
           V+T V+ Y  WI
Sbjct: 263 VYTSVATYSPWI 274


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  139 bits (351), Expect = 2e-33
 Identities = 85/256 (33%), Positives = 128/256 (50%), Gaps = 21/256 (8%)

Query: 13  PETNARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHC---VDYQK 69
           P    R+VGG +     WP Q+S+Q R+G    H CGG+LI + WV+TAAHC        
Sbjct: 29  PRMLNRMVGGQDTQEGEWPWQVSIQ-RNGS---HFCGGSLIAEQWVLTAAHCFRNTSETS 84

Query: 70  TFRVVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQL 129
            ++V+ G   L Q      Y  V+++  +P +     A+  D+AL+ L   V   +Y+  
Sbjct: 85  LYQVLLGARQLVQPGPHAMYARVRQVESNPLY--QGTASSADVALVELEAPVPFTNYILP 142

Query: 130 GVLPQEGAILANNSPCYITGWGKTKTNGQLAQ--TLQQAYLPSVDYAIC-------SSSS 180
             LP    I      C++TGWG       L +   LQ+  +P +D   C       +   
Sbjct: 143 VCLPDPSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFG 202

Query: 181 YWGSTVKNTMVCAG-GDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPT 239
           Y   T+KN M+CAG  +G +  C+GDSGGPL CLV   +   GV S+    GC    +P 
Sbjct: 203 YQPKTIKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQSWLQAGVISW--GEGCARQNRPG 260

Query: 240 VFTQVSAYISWINNVI 255
           V+ +V+A+ +WI+ +I
Sbjct: 261 VYIRVTAHHNWIHRII 276


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  139 bits (350), Expect = 2e-33
 Identities = 84/242 (34%), Positives = 127/242 (52%), Gaps = 15/242 (6%)

Query: 16  NARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCV---DYQKTFR 72
           ++R+VGG  +  + WP Q SLQ++     YH CGG++I   W++TAAHCV      K++ 
Sbjct: 214 SSRIVGGNMSLLSQWPWQASLQFQG----YHLCGGSVITPLWIITAAHCVYDLYLPKSWT 269

Query: 73  VVAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVL 132
           +  G  +L  N        V+KIV H  +    +  G DIAL++LA  +T N  +Q   L
Sbjct: 270 IQVGLVSLLDNPAPSHL--VEKIVYHSKYKPKRL--GNDIALMKLAGPLTFNEMIQPVCL 325

Query: 133 PQEGAILANNSPCYITGWGKTKTN-GQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMV 191
           P       +   C+ +GWG T+   G  +  L  A +P +   IC+    +G  +  +M+
Sbjct: 326 PNSEENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSML 385

Query: 192 CAGG-DGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISW 250
           CAG   G    CQGDSGGPL C     + + G TSF    GC    KP V+T+V++++ W
Sbjct: 386 CAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGATSF--GIGCAEVNKPGVYTRVTSFLDW 443

Query: 251 IN 252
           I+
Sbjct: 444 IH 445


>gi|4503549 neutrophil elastase preproprotein [Homo sapiens]
          Length = 267

 Score =  139 bits (349), Expect = 3e-33
 Identities = 93/242 (38%), Positives = 130/242 (53%), Gaps = 26/242 (10%)

Query: 17  ARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQ--KTFRVV 74
           + +VGG  A  ++WP  +SLQ R G    H CG TLI  N+VM+AAHCV     +  RVV
Sbjct: 28  SEIVGGRRARPHAWPFMVSLQLRGG----HFCGATLIAPNFVMSAAHCVANVNVRAVRVV 83

Query: 75  AGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQ 134
            G HNLS+ + T Q  +VQ+I  + Y   D V    DI +L+L  S T+N+ VQ+  LP 
Sbjct: 84  LGAHNLSRREPTRQVFAVQRIFENGY---DPVNLLNDIVILQLNGSATINANVQVAQLPA 140

Query: 135 EGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAG 194
           +G  L N   C   GWG    N  +A  LQ+  + +V  ++C  S+          VC  
Sbjct: 141 QGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNV-TVVTSLCRRSN----------VCTL 189

Query: 195 GDGVRSG-CQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINN 253
             G ++G C GDSG PL C  NG   +HG+ SFV   GC     P  F  V+ +++WI++
Sbjct: 190 VRGRQAGVCFGDSGSPLVC--NG--LIHGIASFVRG-GCASGLYPDAFAPVAQFVNWIDS 244

Query: 254 VI 255
           +I
Sbjct: 245 II 246


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  138 bits (348), Expect = 4e-33
 Identities = 81/251 (32%), Positives = 127/251 (50%), Gaps = 20/251 (7%)

Query: 17  ARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVD---YQKTFRV 73
           AR+ GG+ A    WP Q+S+ Y       H CGG+L+ + WV++AAHC     +++ + V
Sbjct: 43  ARITGGSSAVAGQWPWQVSITYEG----VHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEV 98

Query: 74  VAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLP 133
             G H L       +  +++ I+ HP +  +      DIALL+L++ +T + Y++   LP
Sbjct: 99  KLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQG--DIALLQLSRPITFSRYIRPICLP 156

Query: 134 QEGAILANNSPCYITGWGKTKTNGQL--AQTLQQAYLPSVDYAICS------SSSYWGST 185
              A   N   C +TGWG    +  L   + LQQ  +P +    C+      +       
Sbjct: 157 AANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNCLYNIDAKPEEPHF 216

Query: 186 VKNTMVCAG-GDGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQV 244
           V+  MVCAG  +G +  CQGDSGGPL C V G + + G+ S+     C    +P V+T  
Sbjct: 217 VQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSW--GDACGARNRPGVYTLA 274

Query: 245 SAYISWINNVI 255
           S+Y SWI + +
Sbjct: 275 SSYASWIQSKV 285


>gi|148231605 ovochymase 2 [Homo sapiens]
          Length = 564

 Score =  138 bits (347), Expect = 5e-33
 Identities = 88/259 (33%), Positives = 139/259 (53%), Gaps = 30/259 (11%)

Query: 17  ARVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCV---DYQKTFRV 73
           +R++GG++  + S+P Q+SL+ R    + H CGG+++   WV+TAAHC+   +   T  V
Sbjct: 50  SRILGGSQVEKGSYPWQVSLKQR----QKHICGGSIVSPQWVITAAHCIANRNIVSTLNV 105

Query: 74  VAGDHNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLP 133
            AG+++LSQ D  EQ ++++ +++HP++ S      YDIALL++A +     +V    LP
Sbjct: 106 TAGEYDLSQTDPGEQTLTIETVIIHPHF-STKKPMDYDIALLKMAGAFQFGHFVGPICLP 164

Query: 134 QEGAILANNSPCYITGWGKTKTNGQLAQTLQQAYLPSVDYAICSSSSYWGSTVK-----N 188
           +          C   GWG+    G L+Q LQ+  LP + +  C ++     T+K      
Sbjct: 165 ELREQFEAGFICTTAGWGRLTEGGVLSQVLQEVNLPILTWEECVAALL---TLKRPISGK 221

Query: 189 TMVCAG-GDGVRSGCQGDSGGPLHCL-VNGKYSVHGVTSFVSSRGC------NVSR---- 236
           T +C G  DG R  CQGDSGG L C    G +++ GVTS+    GC      NV +    
Sbjct: 222 TFLCTGFPDGGRDACQGDSGGSLMCRNKKGAWTLAGVTSW--GLGCGRGWRNNVRKSDQG 279

Query: 237 KPTVFTQVSAYISWINNVI 255
            P +FT +S  + WI+  I
Sbjct: 280 SPGIFTDISKVLPWIHEHI 298


>gi|4506147 protease, serine, 2 preproprotein [Homo sapiens]
          Length = 247

 Score =  137 bits (346), Expect = 7e-33
 Identities = 88/243 (36%), Positives = 132/243 (54%), Gaps = 21/243 (8%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGD 77
           ++VGG     NS P Q+SL      S YH CGG+LI + WV++A HC  Y+   +V  G+
Sbjct: 23  KIVGGYICEENSVPYQVSLN-----SGYHFCGGSLISEQWVVSAGHC--YKSRIQVRLGE 75

Query: 78  HNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGA 137
           HN+   +G EQ+++  KI+ HP +NS  +    DI L++L+    +NS V    LP   A
Sbjct: 76  HNIEVLEGNEQFINAAKIIRHPKYNSRTL--DNDILLIKLSSPAVINSRVSAISLPT--A 131

Query: 138 ILANNSPCYITGWGKTKTNG-QLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGG- 195
             A  +   I+GWG T ++G      LQ    P +  A C +S  +   + N M C G  
Sbjct: 132 PPAAGTESLISGWGNTLSSGADYPDELQCLDAPVLSQAECEAS--YPGKITNNMFCVGFL 189

Query: 196 DGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVI 255
           +G +  CQGDSGGP+  + NG+  + G+ S+    GC    +P V+T+V  Y+ WI + I
Sbjct: 190 EGGKDSCQGDSGGPV--VSNGE--LQGIVSW--GYGCAQKNRPGVYTKVYNYVDWIKDTI 243

Query: 256 ASN 258
           A+N
Sbjct: 244 AAN 246


>gi|170296790 mesotrypsin isoform 1 preproprotein [Homo sapiens]
          Length = 304

 Score =  137 bits (346), Expect = 7e-33
 Identities = 88/243 (36%), Positives = 132/243 (54%), Gaps = 21/243 (8%)

Query: 18  RVVGGTEAGRNSWPSQISLQYRSGGSRYHTCGGTLIRQNWVMTAAHCVDYQKTFRVVAGD 77
           ++VGG     NS P Q+SL   S     H CGG+LI + WV++AAHC  Y+   +V  G+
Sbjct: 80  KIVGGYTCEENSLPYQVSLNSGS-----HFCGGSLISEQWVVSAAHC--YKTRIQVRLGE 132

Query: 78  HNLSQNDGTEQYVSVQKIVVHPYWNSDNVAAGYDIALLRLAQSVTLNSYVQLGVLPQEGA 137
           HN+   +G EQ+++  KI+ HP +N D +    DI L++L+    +N+ V    LP   A
Sbjct: 133 HNIKVLEGNEQFINAAKIIRHPKYNRDTL--DNDIMLIKLSSPAVINARVSTISLPT--A 188

Query: 138 ILANNSPCYITGWGKTKTNG-QLAQTLQQAYLPSVDYAICSSSSYWGSTVKNTMVCAGG- 195
             A  + C I+GWG T + G      L+    P +  A C +S  +   + N+M C G  
Sbjct: 189 PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKAS--YPGKITNSMFCVGFL 246

Query: 196 DGVRSGCQGDSGGPLHCLVNGKYSVHGVTSFVSSRGCNVSRKPTVFTQVSAYISWINNVI 255
           +G +  CQ DSGGP+ C  NG+  + GV S+    GC    +P V+T+V  Y+ WI + I
Sbjct: 247 EGGKDSCQRDSGGPVVC--NGQ--LQGVVSW--GHGCAWKNRPGVYTKVYNYVDWIKDTI 300

Query: 256 ASN 258
           A+N
Sbjct: 301 AAN 303


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,921,169
Number of Sequences: 37866
Number of extensions: 424892
Number of successful extensions: 1530
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 807
Number of HSP's gapped (non-prelim): 200
length of query: 258
length of database: 18,247,518
effective HSP length: 100
effective length of query: 158
effective length of database: 14,460,918
effective search space: 2284825044
effective search space used: 2284825044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.