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Search of human proteins with 58331175
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens]
(284 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens] 576 e-165
gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens] 576 e-165
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 50 2e-06
gi|4505257 moesin [Homo sapiens] 46 3e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 46 4e-05
gi|21396500 HIRA interacting protein 3 [Homo sapiens] 46 4e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 45 6e-05
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 45 9e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 45 9e-05
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 44 2e-04
gi|154146223 splicing factor, arginine/serine-rich 130 [Homo sap... 44 2e-04
gi|154146193 splicing factor, arginine/serine-rich 130 [Homo sap... 44 2e-04
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 44 2e-04
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 44 2e-04
gi|4506467 radixin [Homo sapiens] 44 2e-04
gi|4504487 histidine rich calcium binding protein precursor [Hom... 44 2e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 43 3e-04
gi|115529449 upstream binding transcription factor, RNA polymera... 43 3e-04
gi|115529451 upstream binding transcription factor, RNA polymera... 43 3e-04
gi|7657671 upstream binding transcription factor, RNA polymerase... 43 3e-04
gi|217330641 IWS1 homolog [Homo sapiens] 43 4e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 42 5e-04
gi|161702986 ezrin [Homo sapiens] 42 6e-04
gi|21614499 ezrin [Homo sapiens] 42 6e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 42 6e-04
gi|55956788 nucleolin [Homo sapiens] 41 0.001
gi|55741677 SET domain containing 1A [Homo sapiens] 41 0.001
gi|210032580 SET domain containing 1B [Homo sapiens] 41 0.001
gi|9257192 adducin 2 isoform a [Homo sapiens] 40 0.002
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 40 0.002
>gi|58331177 ermin, ERM-like protein isoform a [Homo sapiens]
Length = 297
Score = 576 bits (1484), Expect = e-165
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 60
MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE
Sbjct: 14 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 73
Query: 61 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 120
RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL
Sbjct: 74 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 133
Query: 121 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 180
SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK
Sbjct: 134 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 193
Query: 181 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 240
VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE
Sbjct: 194 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 253
Query: 241 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 284
QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL
Sbjct: 254 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 297
>gi|58331175 ermin, ERM-like protein isoform b [Homo sapiens]
Length = 284
Score = 576 bits (1484), Expect = e-165
Identities = 284/284 (100%), Positives = 284/284 (100%)
Query: 1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 60
MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE
Sbjct: 1 MTDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEE 60
Query: 61 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 120
RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL
Sbjct: 61 RRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 120
Query: 121 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 180
SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK
Sbjct: 121 SGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQK 180
Query: 181 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 240
VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE
Sbjct: 181 VWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDE 240
Query: 241 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 284
QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL
Sbjct: 241 QPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMMHL 284
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/194 (22%), Positives = 89/194 (45%), Gaps = 16/194 (8%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
+E +K++ + E+KM +E E+ K + ++M +E WE+
Sbjct: 8 REREKKMREEEEMMREQEEKM-QEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 66
Query: 118 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSK--- 174
Q + QKE++ EQ + E E+R + ++E + +K +Q + + +
Sbjct: 67 EEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQEEK 126
Query: 175 -HDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE---------GDA 222
++E+ +W+ EE + ++ E+++R E K ++ EE Q +EE G+A
Sbjct: 127 MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMRDVEPAGGEA 186
Query: 223 SEDSPLSSASSQAV 236
E SP + ++Q +
Sbjct: 187 GEGSPQDNPTAQEI 200
Score = 28.1 bits (61), Expect = 9.1
Identities = 14/61 (22%), Positives = 33/61 (54%), Gaps = 2/61 (3%)
Query: 125 QEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDE 184
+E R +ER E+ ++EEE+ R+ + + E + ++ + ++E+K+W++
Sbjct: 2 REEERMRER--EKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQ 59
Query: 185 E 185
E
Sbjct: 60 E 60
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 46.2 bits (108), Expect = 3e-05
Identities = 63/272 (23%), Positives = 113/272 (41%), Gaps = 23/272 (8%)
Query: 14 NGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR--KLQGNMLLN 71
N K E ++ KI E ++ L ++E + A + ++ RR +L+
Sbjct: 325 NEKKKREMAEKEKEKIEREKEELMERLK--QIEEQTKKAQQELEEQTRRALELEQERKRA 382
Query: 72 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG--SNQEIRR 129
S +K+ KE E + +L + S D+ +E E L+ S E+ R
Sbjct: 383 QSEAEKLAKERQEAEE-------AKEALLQASRDQKKTQEQLALEMAELTARISQLEMAR 435
Query: 130 QKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDD 189
QK+ +++ +++ AE++ P A+ ++ DE+ + E D
Sbjct: 436 QKKESEAVEWQQKAQMVQEDLEKTRAELK-TAMSTPHVAEPAENEQDEQDENGAEASADL 494
Query: 190 DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSD 249
D D E +K+E V + + + S L++A ++ +
Sbjct: 495 RADAMAKDRSEEERTTEAEKNERVQKHLK----ALTSELANARDESKKTANDMIHAENMR 550
Query: 250 ISRNAYSRYNTISYRKIRKGNTKQRIDEFESM 281
+ R+ Y + R+IR+GNTKQRIDEFESM
Sbjct: 551 LGRDKYK-----TLRQIRQGNTKQRIDEFESM 577
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 45.8 bits (107), Expect = 4e-05
Identities = 44/199 (22%), Positives = 87/199 (43%), Gaps = 16/199 (8%)
Query: 58 QEER-RKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLS-LQETSADEMTFREGHQW 115
Q+ER R+ + M M ++ K EE++ K + + ++M +E + W
Sbjct: 364 QDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMW 423
Query: 116 EKIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------EWLGFRKPS 166
E+ Q + QKE++ EQ +E++E +++ K E+ W +
Sbjct: 424 EQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 483
Query: 167 QADML----HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDA 222
Q D + D+EQK+WD+E + D +++E R+ E KK ++ + +EE
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEE-RMREQKKMWQQEEKMREEKKT 542
Query: 223 SEDSPLSSASSQAVTPDEQ 241
E + + + +E+
Sbjct: 543 QEQEKKTWDQEEKMREEER 561
Score = 39.7 bits (91), Expect = 0.003
Identities = 43/215 (20%), Positives = 87/215 (40%), Gaps = 33/215 (15%)
Query: 60 ERRKLQGNMLLNSSMEDKMLKENP-----EEKLFIVHKAITDLSLQETSADE-MTFREGH 113
E++KL+ E+KM ++ EEK++ + + + Q ++ M +E
Sbjct: 301 EQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEER 360
Query: 114 QWEKIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------------- 157
WE+ +E R++E++ EQ K +E+E +R+ K + E
Sbjct: 361 MWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Query: 158 --------EWLGFRKPSQADML---HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEF 206
EW R P Q + L ++E+K+W++E D + E ++ E
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 207 KKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 241
++ E+ +EE ++ + + DE+
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER 515
Score = 34.3 bits (77), Expect = 0.13
Identities = 26/151 (17%), Positives = 67/151 (44%), Gaps = 4/151 (2%)
Query: 100 QETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEW 159
+E E + Q EK+ +E R +K R E+ ++E+E++ ++ + + E
Sbjct: 538 EEKKTQEQEKKTWDQEEKMREEERMRE-REKKMREEEEMMREQEEKMQEQEEKMREQEEK 596
Query: 160 LGFRKPSQADMLHSKHDEEQKVWDEEIDD---DDDDNCNNDEDEVRVIEFKKKHEEVSQF 216
+ ++ + ++E+K+W++E +D + ++ E++++ E K +E
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656
Query: 217 KEEGDASEDSPLSSASSQAVTPDEQPTLGKK 247
++E E + + E+ G++
Sbjct: 657 EQEEKMREQEEKMQGQEEKMREQEEKMQGQE 687
Score = 33.5 bits (75), Expect = 0.22
Identities = 51/224 (22%), Positives = 95/224 (42%), Gaps = 36/224 (16%)
Query: 23 QQTITKISEELTDVDSPLPH-YRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 81
+ TIT +EEL ++ L R+ S + + +E +RKL+ L ++ L+E
Sbjct: 177 RNTIT--NEELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE 234
Query: 82 N---PEEKLFIVHKAITD----LSLQETSADEMTFREGHQWEKIP-----LSGSNQEIRR 129
EE+L K I + QE E + Q EK+ L +E+R
Sbjct: 235 EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELRE 294
Query: 130 QKERITEQP-LKEEEDE---------DRKNKGHQAAEIEW-----LGFRKPSQADMLHSK 174
Q++ + EQ L+E+E++ +++ K + E W L ++ +
Sbjct: 295 QEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 354
Query: 175 HDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 218
D+E+++W++ D+ E+ +R E + EE Q +E
Sbjct: 355 RDQEERMWEQ------DERLREKEERMREQEKMWEQEEKMQEEE 392
Score = 32.3 bits (72), Expect = 0.48
Identities = 30/161 (18%), Positives = 69/161 (42%), Gaps = 22/161 (13%)
Query: 59 EERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKI 118
E+ K+Q E+KM ++ E+K+ + + + ++M +E WE+
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE------QEEKMQEQEEKMWEQ- 651
Query: 119 PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEE 178
+++R Q+E++ EQ K + E++ + + + + R+ + +E
Sbjct: 652 -----EEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE-----KMRGQE 701
Query: 179 QKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 219
+K+W +E + +E E ++K E + KE+
Sbjct: 702 EKMWGQE-----EKMWGQEEKMWGQEEMREKEERIRDQKEK 737
Score = 30.8 bits (68), Expect = 1.4
Identities = 29/165 (17%), Positives = 77/165 (46%), Gaps = 13/165 (7%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
QE+ R+ + M E+KM + E+K++ + + + + +E + W++
Sbjct: 478 QEKMREQEDQMW---EQEEKM--RDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532
Query: 118 IPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEIEWLGFRKPSQADMLHSK 174
++ + Q+++ +Q K E+E +R+ K + E E + ++ +
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMRE--EEEMMREQEEKMQEQEEKM 590
Query: 175 HDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 219
++E+K+W++E + + +++E ++++ E+ Q +EE
Sbjct: 591 REQEEKMWEQEEKMQEQEEKMWEQEEKM---WEQEEEDKMQEQEE 632
>gi|21396500 HIRA interacting protein 3 [Homo sapiens]
Length = 556
Score = 45.8 bits (107), Expect = 4e-05
Identities = 56/280 (20%), Positives = 112/280 (40%), Gaps = 34/280 (12%)
Query: 16 DKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSME 75
++ P + + + S+E D P E KG ++ ++ +S+
Sbjct: 129 EENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVS 188
Query: 76 DKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERIT 135
K +E EE ++ + +A ++ +G + K S +EI QK+
Sbjct: 189 RKQAREESEE---------SEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQR 239
Query: 136 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQAD-MLHSKHDEEQKVWDEEIDDDDDDNC 194
E+ ++EEE E+ + KG G RK ++ + K ++ + D + +++ +
Sbjct: 240 EEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAA 299
Query: 195 NNDEDEVRVIE--FKKKHEEVSQFK----------EEGDASEDSPLSSASSQAVTPDEQP 242
++ +D R E ++K E+ +Q K +E D+ + P + S +
Sbjct: 300 SSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGS-- 357
Query: 243 TLGKKSDISRNAY----------SRYNTISYRKIRKGNTK 272
T G++SD+ R R N S + RKG T+
Sbjct: 358 TSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRKGRTR 397
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 45.4 bits (106), Expect = 6e-05
Identities = 59/296 (19%), Positives = 127/296 (42%), Gaps = 42/296 (14%)
Query: 23 QQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNM-------LLNSSME 75
Q + ++ +L LP +++ + L K Q KLQ + LN E
Sbjct: 229 QLNVKELKRKLERAKLLLPQQQLQAEADH-LGKELQSVSAKLQAQVEENELWNRLNQQQE 287
Query: 76 DKMLKENP-----EEKLFIVHKAITDLSLQETSADEMTF--------REGHQWEKIPLSG 122
+KM ++ EEK+ + I + + +EM + +E WEK
Sbjct: 288 EKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 347
Query: 123 SNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEIEWLGFRK--------PSQADML 171
+E ++E+I EQ K +E+E +++ + Q A++ W K Q +M+
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM-WRQEEKIREQEEKIREQEEMM 406
Query: 172 HSKH----DEEQKVWDEEID-DDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDS 226
+ ++E+K+W++E + + ++ E+++R E KK E+ + +E+ + ++
Sbjct: 407 QEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQE-KKIREQEEKIREQEEMMQEQ 465
Query: 227 PLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESMM 282
+ +++ + ++ + R + +KIR+ +++I E E MM
Sbjct: 466 EEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIRE-QEKKIRE--QEEKIREQEEMM 518
Score = 40.4 bits (93), Expect = 0.002
Identities = 44/179 (24%), Positives = 80/179 (44%), Gaps = 33/179 (18%)
Query: 56 GSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITD----LSLQETSADEMTFRE 111
G QEE+ Q + E+KM ++ EEK+ K I + + QE E +
Sbjct: 414 GEQEEKMWEQEEEM--QEQEEKMRRQ--EEKIREQEKKIREQEEKIREQEEMMQEQEEKM 469
Query: 112 GHQWEKI-----PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPS 166
G Q K+ + +++RRQ+E+I EQ K E E++ +
Sbjct: 470 GEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE---------------- 513
Query: 167 QADMLHSKHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 224
Q +M+ ++E+K+W+ EE + ++ E+++R E K + +EV ++E E
Sbjct: 514 QEEMMQ---EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 34.3 bits (77), Expect = 0.13
Identities = 36/165 (21%), Positives = 75/165 (45%), Gaps = 6/165 (3%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKE-NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWE 116
QEE+R+ + + +++ K EEK+ + I + QE E + G Q E
Sbjct: 362 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE---QEEMMQEQEEKMGEQEE 418
Query: 117 KIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 176
K+ + + +K R E+ ++E+E + R+ + + E + ++ + +
Sbjct: 419 KMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCE 478
Query: 177 EEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE 219
+E K+ + EE ++ E ++R E K ++ EE+ Q +EE
Sbjct: 479 QEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 44.7 bits (104), Expect = 9e-05
Identities = 39/175 (22%), Positives = 80/175 (45%), Gaps = 11/175 (6%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSA----DEMTFREGH 113
QEE+ + Q + E KM ++ EEK+ K + QE +E +
Sbjct: 435 QEEKIREQEEKI--REQEKKMWRQ--EEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEE 490
Query: 114 QW-EKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLH 172
W +K + ++IR+Q+E++ Q K E E++ + + + R+ +
Sbjct: 491 IWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREE 550
Query: 173 SKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK--KKHEEVSQFKEEGDASED 225
K E++K+W+EE + +D E+++R E K ++ E++ + +E+ E+
Sbjct: 551 EKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEE 605
Score = 41.6 bits (96), Expect = 8e-04
Identities = 40/187 (21%), Positives = 83/187 (44%), Gaps = 19/187 (10%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
+EE+R+ Q EDKM ++ EEK + + + QE E + Q EK
Sbjct: 561 EEEKRQEQ---------EDKMWRQ--EEK---IREQEEKVWRQEEKIREQEEKRQEQEEK 606
Query: 118 IPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 175
+ ++IR Q+E+I EQ ++E+E++ R+ + + E +G ++ +
Sbjct: 607 --MWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQ 664
Query: 176 DEEQKVW-DEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQ 234
++E+ +W EE + + E+++R E + +E +++E E +
Sbjct: 665 EQEETMWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEE 724
Query: 235 AVTPDEQ 241
+ E+
Sbjct: 725 KMRRQEE 731
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/211 (19%), Positives = 102/211 (48%), Gaps = 17/211 (8%)
Query: 75 EDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERI 134
E+K+ K+ EEK++ + I + + +E +R+ + + +E ++E+I
Sbjct: 502 EEKIRKQ--EEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKI 559
Query: 135 TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQA-DMLHSKHDEEQKVW-DEEIDDDDDD 192
E+ ++E+++ + + E E +R+ + + + ++E+K+W EE + ++
Sbjct: 560 WEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEE 619
Query: 193 NCNNDEDEVRVIEFK-KKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 251
E+++R E K ++ EE++Q +EE ++ + + +++ T+ ++ +
Sbjct: 620 KIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKM--CEQEEKMQEQEETMWRQEEKI 677
Query: 252 RNAYSRYNTISYRKIRKGNTKQRIDEFESMM 282
R +KIR+ +++I E E MM
Sbjct: 678 RE--------QEKKIRE--QEEKIREQEEMM 698
Score = 40.0 bits (92), Expect = 0.002
Identities = 37/198 (18%), Positives = 95/198 (47%), Gaps = 17/198 (8%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
+EE+R+ Q M E+K+ + +E+++ + + + + +E +R Q EK
Sbjct: 468 EEEKRQEQEEMW---RQEEKI---HEQEEIWRQKEKMHEQEEKIRKQEEKVWR---QEEK 518
Query: 118 IPLSGSNQEIRRQKERI--TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 175
I ++IR Q+E++ E+ ++E+E+ R+ + E W ++ Q D + +
Sbjct: 519 I--REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQE 576
Query: 176 D----EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSA 231
+ +E+KVW +E + + +++E + +K E+ + +E+ + +
Sbjct: 577 EKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIR 636
Query: 232 SSQAVTPDEQPTLGKKSD 249
+ +T +++ +G++ +
Sbjct: 637 EQEEMTQEQEEKMGEQEE 654
Score = 39.3 bits (90), Expect = 0.004
Identities = 51/272 (18%), Positives = 112/272 (41%), Gaps = 31/272 (11%)
Query: 23 QQTITKISEELTDVDSPL-PHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 81
Q + ++ E D+ S L ++ LE AL+ + ++++ +++ KE
Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA--------DRYIEELTKE 201
Query: 82 NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKER----ITEQ 137
L + ITD L+E +A + + EK + + +E++R+ ER + +Q
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
Query: 138 PLKEEEDEDRKNKGHQAAEIEW------LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDD 191
L+ E D K +A+++ L R Q + + +E+ + W+E+I + +
Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQE 320
Query: 192 DNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 251
+ E+++R E K + +E +++E + + + E+ K+ +
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 380
Query: 252 RNAYSRYNTISYRKIRKGNTKQRIDEFESMMH 283
R + +++I E E MH
Sbjct: 381 RQEEMMW-----------EKEEKIRELEEKMH 401
Score = 38.9 bits (89), Expect = 0.005
Identities = 37/190 (19%), Positives = 82/190 (43%), Gaps = 24/190 (12%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
+EE+ + Q M+ + + L+E E+ + I + + +++ +E Q ++
Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQ-----EKIREQEEKRQEEEKIREQEKRQEQE 429
Query: 118 IPLSGSNQEIRRQKERITEQPLK--------EEEDEDRKNKGHQAAEIEWLGFRKPS--- 166
+ ++IR Q+E+I EQ K E+++ R+ + Q E W K
Sbjct: 430 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489
Query: 167 ----QADMLHSKHD----EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 218
Q + +H + + +E+KVW +E + + +++E + +K E+ ++E
Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWRE 549
Query: 219 EGDASEDSPL 228
E E +
Sbjct: 550 EEKMHEQEKI 559
Score = 38.1 bits (87), Expect = 0.009
Identities = 38/173 (21%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
QEE+R+ Q + + + +E +E+ + + + QE E + G Q EK
Sbjct: 596 QEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEK 655
Query: 118 I-----PLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLH 172
+ + + + RQ+E+I EQ K E E++ + Q +M+
Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIRE----------------QEEMMQ 699
Query: 173 SKHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 224
++E+K+W+ EE + ++ E+++R E K +EV ++E E
Sbjct: 700 ---EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 749
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 44.7 bits (104), Expect = 9e-05
Identities = 37/193 (19%), Positives = 88/193 (45%), Gaps = 13/193 (6%)
Query: 56 GSQEERRKLQGNMLLNSSMEDKMLKENP-----EEKLFIVHKAITDLSLQETSADEMTFR 110
G QEE+ + Q + E+++ K+ EE++ + + + Q +E +
Sbjct: 223 GEQEEQMRKQEEQM--GEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLK 280
Query: 111 EGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM 170
+ Q E+ +G +E R++E + ++E+E++ R+ + + E +G ++ +
Sbjct: 281 QKEQTEQEEQTGEQEEQMREQE----EQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Query: 171 LHSKHDEEQKVW-DEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEEGDASEDSPL 228
++++++W EE + ++ E++VR E + +K EE + +EE ++ +
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQM 396
Query: 229 SSASSQAVTPDEQ 241
Q EQ
Sbjct: 397 GEQKEQMGEQKEQ 409
Score = 32.0 bits (71), Expect = 0.63
Identities = 23/143 (16%), Positives = 62/143 (43%), Gaps = 1/143 (0%)
Query: 100 QETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEW 159
QE E + G Q E++ + ++ R E+ + E+E++ +K + + E
Sbjct: 197 QEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQ 256
Query: 160 LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKE 218
+ ++ + ++E+++ ++ + ++ E+++R E + ++ EE + +E
Sbjct: 257 MRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQE 316
Query: 219 EGDASEDSPLSSASSQAVTPDEQ 241
E ++ + Q EQ
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQ 339
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 43.9 bits (102), Expect = 2e-04
Identities = 39/178 (21%), Positives = 79/178 (44%), Gaps = 5/178 (2%)
Query: 67 NMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQE 126
++L +E ++ E E H+ ++ S Q T E EK+P S E
Sbjct: 293 SILPGGQVEPDLVLEEVEPPWEDAHQDVST-SPQGTEVVPAYEEENKAVEKMPRELSRIE 351
Query: 127 IRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDE-- 184
++ E E+ +EEE+E+ + + +G + S+ D + +QK+W+E
Sbjct: 352 EEKEDEEEEEEEEEEEEEEEVTEVLLDSCVVSQVGVGQ-SEEDGTRPQSTSDQKLWEEVG 410
Query: 185 -EIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 241
E + ++ + +EV E +K+ ++ ++ KEE +A ++ S + P+ Q
Sbjct: 411 EEAKKEAEEKAKEEAEEVAEEEAEKEPQDWAETKEEPEAEAEAASSGVPATKQHPEVQ 468
>gi|154146223 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/294 (19%), Positives = 118/294 (40%), Gaps = 38/294 (12%)
Query: 3 DVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR 62
D P +++ + D+ E+ + S ++T SP+P E + +T+ +E +
Sbjct: 278 DGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ---EEHSDPEMTEEEKEYQM 334
Query: 63 KLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG 122
L MLL ++L + +E+++ V K D + T A + + G
Sbjct: 335 MLLTKMLLT-----EILLDVTDEEIYYVAK---DAHRKATKAPAKQLAQSSALASLTGLG 386
Query: 123 ------SNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 176
S + +R +E + +DE+ +++ Q E W RK + +LH K
Sbjct: 387 GLGGYGSGDSEDERSDRGSES--SDTDDEELRHRIRQKQEAFW---RKEKEQQLLHDKQM 441
Query: 177 EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPL-------- 228
EE+K E + + ++ + +++ + ++E ++ +V K+ S L
Sbjct: 442 EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501
Query: 229 --------SSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQR 274
S +SS + T S +S ++YS + S R + K++
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
>gi|154146193 splicing factor, arginine/serine-rich 130 [Homo
sapiens]
Length = 805
Score = 43.9 bits (102), Expect = 2e-04
Identities = 57/294 (19%), Positives = 118/294 (40%), Gaps = 38/294 (12%)
Query: 3 DVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERR 62
D P +++ + D+ E+ + S ++T SP+P E + +T+ +E +
Sbjct: 278 DGPRLPQRSKFDSDEEEEDTENVEAASSGKVTRSPSPVPQ---EEHSDPEMTEEEKEYQM 334
Query: 63 KLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSG 122
L MLL ++L + +E+++ V K D + T A + + G
Sbjct: 335 MLLTKMLLT-----EILLDVTDEEIYYVAK---DAHRKATKAPAKQLAQSSALASLTGLG 386
Query: 123 ------SNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHD 176
S + +R +E + +DE+ +++ Q E W RK + +LH K
Sbjct: 387 GLGGYGSGDSEDERSDRGSES--SDTDDEELRHRIRQKQEAFW---RKEKEQQLLHDKQM 441
Query: 177 EEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPL-------- 228
EE+K E + + ++ + +++ + ++E ++ +V K+ S L
Sbjct: 442 EEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETTSVLEPKKEHKE 501
Query: 229 --------SSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQR 274
S +SS + T S +S ++YS + S R + K++
Sbjct: 502 KEKQGRSRSGSSSSGSSSSNSRTSSTSSTVSSSSYSSSSGSSRTSSRSSSPKRK 555
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 34/193 (17%)
Query: 72 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEI---- 127
+ +E + +E E++L H+ + D L+E ++ F + + + GS +E
Sbjct: 568 NGLEKDLDEEGSEKEL---HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDS 624
Query: 128 -RRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 186
+++E T + + ++E ++++++ E+ + AD + D ++K+++E
Sbjct: 625 DEKEEEEDTYEKVFDDESDEKEDE-------EYADEKGLEAADKKAEEGDADEKLFEESD 677
Query: 187 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS-------------------EDSP 227
D +D+D + ++ F+ F EE D+S E+ P
Sbjct: 678 DKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737
Query: 228 LSSASSQAVTPDE 240
LS+ SS ++ D+
Sbjct: 738 LSTGSSFILSSDD 750
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/206 (23%), Positives = 96/206 (46%), Gaps = 17/206 (8%)
Query: 48 SLEGALTKGSQEERRKLQGNM--LLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSAD 105
S EG +GS+E+ K + L N E+ + KE+ ++ + ++ ++ + S +
Sbjct: 485 SEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD---LNKESEEEVGPTKESEE 541
Query: 106 EMTFREGHQ--WEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFR 163
+ + +E + EK GS +E +E E+ L EE E ++ E+E
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREF---EENGLEKDLDEEGSEKELHENVLDKELE----- 593
Query: 164 KPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 223
+ ++ + D +KV DEE + + D ++DE E ++K ++ S KE+ + +
Sbjct: 594 -ENDSENSEFEDDGSEKVLDEEGSEREFDE-DSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 224 EDSPLSSASSQAVTPDEQPTLGKKSD 249
++ L +A +A D L ++SD
Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESD 677
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 43.5 bits (101), Expect = 2e-04
Identities = 37/193 (19%), Positives = 85/193 (44%), Gaps = 34/193 (17%)
Query: 72 SSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEI---- 127
+ +E + +E E++L H+ + D L+E ++ F + + + GS +E
Sbjct: 568 NGLEKDLDEEGSEKEL---HENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDS 624
Query: 128 -RRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 186
+++E T + + ++E ++++++ E+ + AD + D ++K+++E
Sbjct: 625 DEKEEEEDTYEKVFDDESDEKEDE-------EYADEKGLEAADKKAEEGDADEKLFEESD 677
Query: 187 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS-------------------EDSP 227
D +D+D + ++ F+ F EE D+S E+ P
Sbjct: 678 DKEDEDADGKEVEDADEKLFEDDDSNEKLFDEEEDSSEKLFDDSDERGTLGGFGSVEEGP 737
Query: 228 LSSASSQAVTPDE 240
LS+ SS ++ D+
Sbjct: 738 LSTGSSFILSSDD 750
Score = 42.7 bits (99), Expect = 4e-04
Identities = 48/206 (23%), Positives = 96/206 (46%), Gaps = 17/206 (8%)
Query: 48 SLEGALTKGSQEERRKLQGNM--LLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSAD 105
S EG +GS+E+ K + L N E+ + KE+ ++ + ++ ++ + S +
Sbjct: 485 SEEGNPVRGSEEDSPKKESKKKTLKNDCEENGLAKESEDD---LNKESEEEVGPTKESEE 541
Query: 106 EMTFREGHQ--WEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFR 163
+ + +E + EK GS +E +E E+ L EE E ++ E+E
Sbjct: 542 DDSEKESDEDCSEKQSEDGSEREF---EENGLEKDLDEEGSEKELHENVLDKELE----- 593
Query: 164 KPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 223
+ ++ + D +KV DEE + + D ++DE E ++K ++ S KE+ + +
Sbjct: 594 -ENDSENSEFEDDGSEKVLDEEGSEREFDE-DSDEKEEEEDTYEKVFDDESDEKEDEEYA 651
Query: 224 EDSPLSSASSQAVTPDEQPTLGKKSD 249
++ L +A +A D L ++SD
Sbjct: 652 DEKGLEAADKKAEEGDADEKLFEESD 677
>gi|4506467 radixin [Homo sapiens]
Length = 583
Score = 43.5 bits (101), Expect = 2e-04
Identities = 32/110 (29%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
Query: 172 HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSA 231
H +HDE E+ ++ N ++E+ RV E +K Q + + S L+ A
Sbjct: 486 HDEHDENNAEASAELSNEGVMNHRSEEE--RVTETQKNERVKKQLQ-----ALSSELAQA 538
Query: 232 SSQAVTPDEQPTLGKKSDISRNAYSRYNTISYRKIRKGNTKQRIDEFESM 281
+ + R+ Y + R+IR+GNTKQRIDEFE+M
Sbjct: 539 RDETKKTQNDVLHAENVKAGRDKYK-----TLRQIRQGNTKQRIDEFEAM 583
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 43.5 bits (101), Expect = 2e-04
Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 4/130 (3%)
Query: 98 SLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEI 157
S Q+ DE+ E H I G E E+ +EEE+E GHQA
Sbjct: 159 SHQDEDEDEVVSSEHHH--HILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRH 216
Query: 158 EWLGFRKPSQADMLHSKH--DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQ 215
G + H H + +E+ DDDDDD+ ++D+D+V + + H
Sbjct: 217 RGHGSEEDEDVSDGHHHHGPSHRHQGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGH 276
Query: 216 FKEEGDASED 225
EE + D
Sbjct: 277 GIEEDEDVSD 286
Score = 32.3 bits (72), Expect = 0.48
Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 19/104 (18%)
Query: 124 NQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWD 183
+ E Q E+ T +++EDE+ + +GH S + EE++ D
Sbjct: 498 DDESSEQGEKGTHHGSRDQEDEEDEEEGHGL------------------SLNQEEEEEED 539
Query: 184 EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSP 227
+E +++++D +E H E + +EEG ED P
Sbjct: 540 KEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEG-LEEDEP 582
Score = 29.6 bits (65), Expect = 3.1
Identities = 28/146 (19%), Positives = 59/146 (40%), Gaps = 13/146 (8%)
Query: 104 ADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQ-----PLKEEEDEDRKNKGHQAAEIE 158
+DE F++ ++ E +P ++ R + E ++ + P + +D + Q I+
Sbjct: 401 SDEEDFQDEYKTE-VPHHHHHRVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIK 459
Query: 159 WLGFRKPSQA---DMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQ 215
+ P D H + D+ + EE + ++D + ++DE K H
Sbjct: 460 EMSHHPPGHTVVKDRSHLRKDDSE----EEKEKEEDPGSHEEDDESSEQGEKGTHHGSRD 515
Query: 216 FKEEGDASEDSPLSSASSQAVTPDEQ 241
++E D E LS + D++
Sbjct: 516 QEDEEDEEEGHGLSLNQEEEEEEDKE 541
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 43.1 bits (100), Expect = 3e-04
Identities = 45/172 (26%), Positives = 82/172 (47%), Gaps = 17/172 (9%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITD----LSLQETSADEMTFREGH 113
QEE+ Q + E+KM ++ EEK+ + I + + QE E + G
Sbjct: 500 QEEKMHDQEEKI--REQEEKMWRQ--EEKIREQEEKIREQEEKIREQEEMMQEQEEKMGE 555
Query: 114 QWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHS 173
Q EK+ +++RRQ+E+I EQ EE+ ++K K + E W K + + +
Sbjct: 556 QEEKMQ---EQEKMRRQEEKIREQ---EEKIREQKEKIREQEEKIWEQEEKIREQEEM-- 607
Query: 174 KHDEEQKVWD-EEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASE 224
++E+K+W+ EE + ++ E+++R E K +EV ++E E
Sbjct: 608 MQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 659
Score = 38.1 bits (87), Expect = 0.009
Identities = 43/208 (20%), Positives = 94/208 (45%), Gaps = 20/208 (9%)
Query: 23 QQTITKISEELTDVDSPL-PHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMEDKMLKE 81
Q + ++ E D+ S L ++ LE AL+ + ++++ +++ KE
Sbjct: 150 QHAVKQLEGEARDLISRLHDSWKFAGELEQALSAVATQKKKA--------DRYIEELTKE 201
Query: 82 NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKER----ITEQ 137
L + ITD L+E +A + + EK + + +E++R+ ER + +Q
Sbjct: 202 RDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQ 261
Query: 138 PLKEEEDEDRKNKGHQAAEIEW------LGFRKPSQADMLHSKHDEEQKVWDEEIDDDDD 191
L+ E D K +A+++ L R Q + + +E+ + W+E+I + +
Sbjct: 262 QLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQ-EQE 320
Query: 192 DNCNNDEDEVRVIEFKKKHEEVSQFKEE 219
+ E+++R E K + +E +++E
Sbjct: 321 EKIREQEEKIREQEEKMRRQEEMMWEKE 348
Score = 35.0 bits (79), Expect = 0.075
Identities = 31/161 (19%), Positives = 69/161 (42%), Gaps = 17/161 (10%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
QEE+ + Q M+ E+KM ++ EE ++ ++M E WEK
Sbjct: 333 QEEKMRRQEEMMWEK--EEKMRRQ--EEMMW-------------EKEEKMRRLEEMMWEK 375
Query: 118 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDE 177
+E ++E+I EQ K +E+E + + + + + ++ + ++
Sbjct: 376 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 435
Query: 178 EQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKE 218
E+K+W +E + + +E E ++ E++ + +E
Sbjct: 436 EKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEE 476
Score = 34.7 bits (78), Expect = 0.098
Identities = 32/153 (20%), Positives = 71/153 (46%), Gaps = 15/153 (9%)
Query: 75 EDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPLSGSNQEIRRQKERI 134
++K+ K+ EEK++ + + D QE E + Q EKI ++IR Q+E+I
Sbjct: 487 QEKIRKQ--EEKVWRQEEKMHD---QEEKIREQEEKMWRQEEKI--REQEEKIREQEEKI 539
Query: 135 TEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSK--------HDEEQKVWDEEI 186
EQ +E E++ + + + + R+ + K ++E+K+W++E
Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEE 599
Query: 187 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 219
+ + +++E + +K E+ + +E+
Sbjct: 600 KIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632
Score = 32.0 bits (71), Expect = 0.63
Identities = 39/170 (22%), Positives = 78/170 (45%), Gaps = 18/170 (10%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPE-----EKLFIVHKAITDLSLQETSADEMTFREG 112
+EE+R+ Q M +++ ++E E EK+ K + QE +
Sbjct: 454 EEEKRQEQEEMW----RQEEKIREQEEIWRQKEKMHEQEK----IRKQEEKVWRQEEKMH 505
Query: 113 HQWEKIPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM 170
Q EKI +++ RQ+E+I EQ ++E+E++ R+ + + E +G ++ +
Sbjct: 506 DQEEKI--REQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Query: 171 LHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFK-KKHEEVSQFKEE 219
+ EE+ EE + + E+++ E K ++ EE+ Q +EE
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEE 613
Score = 28.9 bits (63), Expect = 5.4
Identities = 29/118 (24%), Positives = 57/118 (48%), Gaps = 19/118 (16%)
Query: 56 GSQEERRKLQGNMLLNSS----MEDKMLKENP-----EEKLFIVHKAITDLSLQETSADE 106
G QEE+ + Q M E+K+ ++ EEK++ + I + QE E
Sbjct: 554 GEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIRE---QEEMMQE 610
Query: 107 MTFREGHQWEKI-----PLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEI 157
+ Q EK+ + +++RRQ+E++ EQ L+++E++ ++++ H A I
Sbjct: 611 QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
>gi|115529449 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)
Query: 17 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 76
KPP NG Q K S+EL + L H P E + GS+ +R + S E
Sbjct: 532 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 577
Query: 77 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 132
++K + VH + SL + D ++E + L G N + R +
Sbjct: 578 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 635
Query: 133 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 192
+E +EEDED +++ + + E G D S ++E + DE +DD+D+
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 193 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 233
+ + D+DE +E + SE S SS+SS
Sbjct: 695 DDDEDDDE-----------------DEDNESEGSSSSSSSS 718
>gi|115529451 upstream binding transcription factor, RNA polymerase
I isoform b [Homo sapiens]
Length = 727
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)
Query: 17 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 76
KPP NG Q K S+EL + L H P E + GS+ +R + S E
Sbjct: 532 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 577
Query: 77 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 132
++K + VH + SL + D ++E + L G N + R +
Sbjct: 578 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 635
Query: 133 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 192
+E +EEDED +++ + + E G D S ++E + DE +DD+D+
Sbjct: 636 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 694
Query: 193 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 233
+ + D+DE +E + SE S SS+SS
Sbjct: 695 DDDEDDDE-----------------DEDNESEGSSSSSSSS 718
>gi|7657671 upstream binding transcription factor, RNA polymerase I
isoform a [Homo sapiens]
Length = 764
Score = 43.1 bits (100), Expect = 3e-04
Identities = 57/221 (25%), Positives = 92/221 (41%), Gaps = 38/221 (17%)
Query: 17 KPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEERRKLQGNMLLNSSMED 76
KPP NG Q K S+EL + L H P E + GS+ +R + S E
Sbjct: 569 KPPMNGYQ---KFSQELLS-NGELNHL---PLKERMVEIGSRWQR-------ISQSQKEH 614
Query: 77 KMLKENPEEKLFIVHKAITDLSLQETSADEMTFRE---GHQWEKIPLSGSNQEIRRQK-E 132
++K + VH + SL + D ++E + L G N + R +
Sbjct: 615 YKKLAEEQQKQYKVHLDLWVKSL--SPQDRAAYKEYISNKRKSMTKLRGPNPKSSRTTLQ 672
Query: 133 RITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDD 192
+E +EEDED +++ + + E G D S ++E + DE +DD+D+
Sbjct: 673 SKSESEEDDEEDEDDEDEDEEEEDDE-NGDSSEDGGDSSESSSEDESEDGDENEEDDEDE 731
Query: 193 NCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASS 233
+ + D+DE +E + SE S SS+SS
Sbjct: 732 DDDEDDDE-----------------DEDNESEGSSSSSSSS 755
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 42.7 bits (99), Expect = 4e-04
Identities = 57/275 (20%), Positives = 109/275 (39%), Gaps = 31/275 (11%)
Query: 2 TDVPATFTQAECNGDKPPENGQQTITKISEELTDVDSPLPHYRVEPSLEGALTKGSQEER 61
++ P ++ ++PP+ + SEEL P P S E + S E
Sbjct: 187 SEEPPRHQASDSENEEPPK--PRMSDSESEEL-----PKPQVSDSESEEPPRHQASDSEN 239
Query: 62 RKLQGNMLLNSSMEDKMLKE-NPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEKIPL 120
+L + +S ED + + E + I+D ++ ++ + E + K +
Sbjct: 240 EELPKPRISDSESEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRV 299
Query: 121 SGSNQEIRRQ---KERITE------QPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADM- 170
S S E ++ + TE Q + ++D DR+NKG E++ F S D
Sbjct: 300 SDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDT-EMQNDSFHSDSHMDRK 358
Query: 171 -LHSKHDEEQKVWDEEIDDDDDDNCNNDED----EVRVIEFKKKHEEVSQFK-------E 218
HS EE++ +++D D+D+ +E + V+ + E+ S K +
Sbjct: 359 KFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDAD 418
Query: 219 EGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRN 253
+ D+ S S + + D + GK+ +N
Sbjct: 419 DSDSDAVSDKSGKREKTIASDSEEEAGKELSDKKN 453
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 42.4 bits (98), Expect = 5e-04
Identities = 44/209 (21%), Positives = 80/209 (38%), Gaps = 32/209 (15%)
Query: 60 ERRKLQGNMLLNSSMEDKMLKEN---PEEKLFIVHKAITDLSLQETSADEMTFREGHQWE 116
E +K+Q E+KM +E EK K + ++M +E + WE
Sbjct: 428 EEKKMQEQEKKTRDQEEKMQEEERIREREK-----KMREEEETMREQEEKMQKQEENMWE 482
Query: 117 KIPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI------EWLGFRKPSQ 167
+ Q + QKE++ EQ +E++E +++ K E+ W + Q
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 168 ADML----HSKHDEEQKVWDEEIDDD-----------DDDNCNNDEDEVRVIEFKKKHEE 212
D + D+EQK+WD+E + D + +E+ +R E K + EE
Sbjct: 543 EDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602
Query: 213 VSQFKEEGDASEDSPLSSASSQAVTPDEQ 241
++E E + + E+
Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQEE 631
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/186 (22%), Positives = 82/186 (44%), Gaps = 27/186 (14%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
QEE+ Q L E KM ++ EEK++ K + + +E E RE
Sbjct: 291 QEEKMWRQEERL--REQEGKMREQ--EEKMWRQEKRLREQE-KELREQEKELRE------ 339
Query: 118 IPLSGSNQEIRRQKERITEQPLK--EEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 175
+E+R Q+E++ EQ K E+E++ R+ + + E L ++ +
Sbjct: 340 ------QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMR 393
Query: 176 DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQA 235
D+E+++W++ D+ E+ +R E +K E+V + +EE E + +
Sbjct: 394 DQEERMWEQ------DERLREKEERMR--EQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445
Query: 236 VTPDEQ 241
+ +E+
Sbjct: 446 MQEEER 451
Score = 38.9 bits (89), Expect = 0.005
Identities = 34/162 (20%), Positives = 66/162 (40%), Gaps = 12/162 (7%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
+E +K++ + E+KM +E E+ K + ++M +E WE+
Sbjct: 592 REREKKMREEEEMMREQEEKM-QEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650
Query: 118 IPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDE 177
Q + QKE++ E +E++ K + E W Q M ++
Sbjct: 651 EEKMWEQQRLPEQKEKLWEHEKMQEQE-----KMQEQEEKIW------EQEKMEKKTQEQ 699
Query: 178 EQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEE 219
E+K WD+E +++ ++ E ++ EE Q +EE
Sbjct: 700 EKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEE 741
Score = 34.7 bits (78), Expect = 0.098
Identities = 36/190 (18%), Positives = 77/190 (40%), Gaps = 23/190 (12%)
Query: 53 LTKGSQEERRKL--QGNMLLNSSMEDKMLKENPEEKLFIVH--KAITDLSLQETSADEMT 108
+ K +QE+ +K Q M SM ++ K EE++ K + +EM
Sbjct: 692 MEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Query: 109 FREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEED---EDRKNKGHQAAEIEWLGFRKP 165
+E WE+ Q + QKE++ E +E++ E + Q ++ +
Sbjct: 752 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMR 811
Query: 166 SQADMLHSKHD----EEQKVWDEE------------IDDDDDDNCNNDEDEVRVIEFKKK 209
Q + + + + +E+K+W +E ++ ++ E+++R E K +
Sbjct: 812 GQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMR 871
Query: 210 HEEVSQFKEE 219
+E ++E
Sbjct: 872 GQEEKMREQE 881
Score = 33.9 bits (76), Expect = 0.17
Identities = 36/189 (19%), Positives = 78/189 (41%), Gaps = 31/189 (16%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
QEE+ Q L ++K ++E E+K+ + + + + +E + WE+
Sbjct: 367 QEEKMWRQEERLWE---QEKQMREQ-EQKMRDQEERMWEQDERLREKEERMREQEKMWEQ 422
Query: 118 IPLSGSNQEIRRQKERITEQPLKEEEDE---DRKNKGHQAAEI----------------- 157
+ ++++ Q+++ +Q K +E+E +R+ K + E
Sbjct: 423 VEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE 482
Query: 158 ----EWLGFRKPSQADML---HSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKH 210
EW R P Q + L ++E+K+W++E D + E ++ E ++
Sbjct: 483 QEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 542
Query: 211 EEVSQFKEE 219
E+ +EE
Sbjct: 543 EDQMWEQEE 551
Score = 32.7 bits (73), Expect = 0.37
Identities = 28/130 (21%), Positives = 58/130 (44%), Gaps = 11/130 (8%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKEN--PEEKLFIVHKAITDLSLQETSADEMTFREGHQW 115
QE+ K+ E+KM ++ PE+K K +QE ++M +E W
Sbjct: 634 QEQEEKMWEQEEKMWEQEEKMWEQQRLPEQK----EKLWEHEKMQEQ--EKMQEQEEKIW 687
Query: 116 EKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKH 175
E+ + QE Q+++ +Q EE+ R+ + E E + ++ +
Sbjct: 688 EQEKMEKKTQE---QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744
Query: 176 DEEQKVWDEE 185
++E+++W++E
Sbjct: 745 EQEEEMWEQE 754
Score = 30.4 bits (67), Expect = 1.8
Identities = 27/134 (20%), Positives = 64/134 (47%), Gaps = 11/134 (8%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENP----EEKLFIVHKAITDLSLQETSADEMTFREGH 113
QEE+ + Q M E KM ++ E++++ + + D + +E ++
Sbjct: 516 QEEKIRDQEEMW---GQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQ 572
Query: 114 QWEKIPLSGSNQEIRRQKERITEQP--LKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 171
+ EK + +E R++ER+ E+ ++EEE+ R+ + + E + ++ +
Sbjct: 573 EQEK--KTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQE 630
Query: 172 HSKHDEEQKVWDEE 185
++E+K+W++E
Sbjct: 631 EKMQEQEEKMWEQE 644
Score = 29.6 bits (65), Expect = 3.1
Identities = 30/168 (17%), Positives = 77/168 (45%), Gaps = 4/168 (2%)
Query: 75 EDKMLKENPEEKLFIVHKAITDLSLQ-ETSADEMTFREGHQWEKIPLSGSNQEIRRQKER 133
ED+M ++ EEK+ + + D + E E + Q EK+ +E R +K R
Sbjct: 543 EDQMWEQ--EEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRE-REKKMR 599
Query: 134 ITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDN 193
E+ ++E+E++ ++ + + E + ++ + ++E+K+W++E +
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659
Query: 194 CNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQ 241
++++ E ++ E++ + +E+ E + + T D++
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQE 707
>gi|161702986 ezrin [Homo sapiens]
Length = 586
Score = 42.0 bits (97), Expect = 6e-04
Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 48/241 (19%)
Query: 55 KGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQ 114
K +QEE +L+ D+M +E+L +A+ + QE A E+
Sbjct: 380 KRAQEEAERLEA---------DRMAALRAKEEL--ERQAVDQIKSQEQLAAELA----EY 424
Query: 115 WEKIPLSGSNQEIRRQKERITEQ---PLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 171
KI L +E RR+KE E+ KE +D+ K K E+ + P +
Sbjct: 425 TAKIALL---EEARRRKEDEVEEWQHRAKEAQDDLVKTK----EELHLVMTAPPPPPPPV 477
Query: 172 HS--KHDEEQKVWDEEIDDD------DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 223
+ + ++ + DE + + +D +E + I +K+E V +
Sbjct: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR-------- 529
Query: 224 EDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISY---RKIRKGNTKQRIDEFES 280
+ LSS SQA +++ +DI N R Y R+IR+GNTKQRIDEFE+
Sbjct: 530 QLLTLSSELSQARDENKRT----HNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEA 585
Query: 281 M 281
+
Sbjct: 586 L 586
>gi|21614499 ezrin [Homo sapiens]
Length = 586
Score = 42.0 bits (97), Expect = 6e-04
Identities = 63/241 (26%), Positives = 103/241 (42%), Gaps = 48/241 (19%)
Query: 55 KGSQEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQ 114
K +QEE +L+ D+M +E+L +A+ + QE A E+
Sbjct: 380 KRAQEEAERLEA---------DRMAALRAKEEL--ERQAVDQIKSQEQLAAELA----EY 424
Query: 115 WEKIPLSGSNQEIRRQKERITEQ---PLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 171
KI L +E RR+KE E+ KE +D+ K K E+ + P +
Sbjct: 425 TAKIALL---EEARRRKEDEVEEWQHRAKEAQDDLVKTK----EELHLVMTAPPPPPPPV 477
Query: 172 HS--KHDEEQKVWDEEIDDD------DDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDAS 223
+ + ++ + DE + + +D +E + I +K+E V +
Sbjct: 478 YEPVSYHVQESLQDEGAEPTGYSAELSSEGIRDDRNEEKRITEAEKNERVQR-------- 529
Query: 224 EDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNTISY---RKIRKGNTKQRIDEFES 280
+ LSS SQA +++ +DI N R Y R+IR+GNTKQRIDEFE+
Sbjct: 530 QLLTLSSELSQARDENKRT----HNDIIHNENMRQGRDKYKTLRQIRQGNTKQRIDEFEA 585
Query: 281 M 281
+
Sbjct: 586 L 586
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 42.0 bits (97), Expect = 6e-04
Identities = 40/202 (19%), Positives = 83/202 (41%), Gaps = 31/202 (15%)
Query: 58 QEERRKLQGNMLLNSSMEDKMLKENPEEKLFIVHKAITDLSLQETSADEMTFREGHQWEK 117
++ER K +G +L S E + E L ++ ++ +++ + E + +K
Sbjct: 397 RKERLKKEGKLLTKSQRE---ARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKRKK 453
Query: 118 IPLSGSNQEIRRQKE-----RITEQ----------PLKEEEDEDRKNKGHQAAEIEWLGF 162
IP ++E+ E + EQ P++ EE+ED ++ G +W
Sbjct: 454 IPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLD----DWEAM 509
Query: 163 RKPSQADMLHSKH---------DEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEV 213
+ + + +EE++ +EE +D++ + +E E E ++ E+V
Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKV 569
Query: 214 SQFKEEGDASEDSPLSSASSQA 235
S K+ G + P SS +
Sbjct: 570 SDEKDSGKTLDKKPSKEMSSDS 591
Score = 29.3 bits (64), Expect = 4.1
Identities = 27/138 (19%), Positives = 65/138 (47%), Gaps = 12/138 (8%)
Query: 124 NQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWL--GFRKPSQADMLHSKHDEEQ-- 179
N+ +++K++ ++ KEE+++++K KG A ++ + K + + + +EE+
Sbjct: 309 NEGDKKKKDKKKKKGEKEEKEKEKK-KGPSKATVKAMQEALAKLKEEEERQKREEEERIK 367
Query: 180 -------KVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSAS 232
K +EE + + +++ R KK+ + +++ + E A ++ L
Sbjct: 368 RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQ 427
Query: 233 SQAVTPDEQPTLGKKSDI 250
+Q V + +L KK I
Sbjct: 428 AQGVEVPSKDSLPKKRPI 445
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 11/160 (6%)
Query: 77 KMLKENPEEKLFIVHKAITDLSLQ-ETSADEMTFREGHQWEKIPLSGSNQEIRRQKERIT 135
K P +K KA+T + T + G + IP G+ +KE
Sbjct: 87 KKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAKGAKNGKNAKKEDSD 146
Query: 136 EQPL--KEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDN 193
E+ EE++ED +++ EIE + + A + DE+ + +++ DD++DD+
Sbjct: 147 EEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDS 206
Query: 194 CN--------NDEDEVRVIEFKKKHEEVSQFKEEGDASED 225
+ +V+ K K+ + +EE D ED
Sbjct: 207 EEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDED 246
Score = 41.2 bits (95), Expect = 0.001
Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 10/83 (12%)
Query: 136 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCN 195
E +EE E KG +AA++ P +A + DEE+ DE+ DDD+DD +
Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVV------PVKAKNVAEDEDEEEDDEDEDDDDDEDDEDD 256
Query: 196 NDEDEVRVIEFKKKHEEVSQFKE 218
+DED+ E +++ EE KE
Sbjct: 257 DDEDD----EEEEEEEEEEPVKE 275
Score = 33.5 bits (75), Expect = 0.22
Identities = 18/88 (20%), Positives = 48/88 (54%), Gaps = 6/88 (6%)
Query: 140 KEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDED 199
++++D++ + +A E +K ++ + +K+ E + +E+ +D+DDD+ +DED
Sbjct: 196 EDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDEDDED 255
Query: 200 EVRVIEFKKKHEEVSQFKEEGDASEDSP 227
+ + +E + +EE + +++P
Sbjct: 256 D------DDEDDEEEEEEEEEEPVKEAP 277
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 40.8 bits (94), Expect = 0.001
Identities = 34/143 (23%), Positives = 57/143 (39%), Gaps = 30/143 (20%)
Query: 142 EEDEDRKNKGHQAAEIEWLGFRKPSQAD-------------MLHSKHDEEQKVWDEEIDD 188
EEDED + +A E G + P + + L S+ +E + E D+
Sbjct: 919 EEDEDDPEQEKEAGEPGRPGTKPPKRDEERGKTQGKHRKSFALDSEGEEASQESSSEKDE 978
Query: 189 DDDDNCNNDEDEVRVIEFKKKHEEVSQFKE-----------------EGDASEDSPLSSA 231
+DD+ DED ++ KK EVS ++ E D++ DS SS+
Sbjct: 979 EDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSS 1038
Query: 232 SSQAVTPDEQPTLGKKSDISRNA 254
SS + + + S S ++
Sbjct: 1039 SSSSSSSSSSSSSSSSSSSSESS 1061
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 40.8 bits (94), Expect = 0.001
Identities = 33/109 (30%), Positives = 52/109 (47%), Gaps = 20/109 (18%)
Query: 127 IRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEI 186
+RR+ R E EEDE K S ++ S +EE+ +EE
Sbjct: 1019 VRRRPARPLELDSGGEEDE------------------KESLSEEQESTEEEEEAEEEEEE 1060
Query: 187 DDDDDDNCNNDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQA 235
+DDDDD+ ++D DE + E S+ K+EGD+ E+ +S +S+A
Sbjct: 1061 EDDDDDD-SDDRDESENDDEDTALSEASE-KDEGDSDEEETVSIVTSKA 1107
Score = 32.0 bits (71), Expect = 0.63
Identities = 35/176 (19%), Positives = 69/176 (39%), Gaps = 45/176 (25%)
Query: 112 GHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADML 171
G + EK LS + ++E E+ ++++D+D ++ + E + S+ D
Sbjct: 1033 GEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTALSEASEKD-- 1090
Query: 172 HSKHDEEQKVW------------------DEEIDDDDDDNCNNDEDEVRVIEFKKKHEEV 213
DEE+ V + E + + + DE+EV E +++ EE
Sbjct: 1091 EGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEVVAREEEEEEEEE 1150
Query: 214 SQFKEEGDAS----------EDSPLSSAS---------------SQAVTPDEQPTL 244
EE AS E++ L+ + ++AV P+E+P++
Sbjct: 1151 EMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAVAPEERPSM 1206
>gi|9257192 adducin 2 isoform a [Homo sapiens]
Length = 726
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/149 (26%), Positives = 65/149 (43%), Gaps = 19/149 (12%)
Query: 101 ETSADEMTFREGHQWEKIPLSGSNQEIRRQKERITEQPLKEEEDEDRKNKGHQA---AEI 157
E S+ M R + + +PL QE+ + +I EQ +D K+ G Q+ A +
Sbjct: 469 EKSSSGMPIRIENPNQFVPLYTDPQEVLEMRNKIREQ-----NRQDVKSAGPQSQLLASV 523
Query: 158 EWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDEVRVIEFKKKHEEVSQFK 217
R PS L SK DE+ K DD ++ N ++ E ++ +EV + K
Sbjct: 524 IAEKSRSPSTESQLMSKGDEDTK-------DDSEETVPNPFSQLTDQELEEYKKEVERKK 576
Query: 218 EEGDASEDS----PLSSASSQAVTPDEQP 242
E D +++ P S A S +P + P
Sbjct: 577 LELDGEKETAPEEPGSPAKSAPASPVQSP 605
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 40.4 bits (93), Expect = 0.002
Identities = 29/121 (23%), Positives = 59/121 (48%), Gaps = 17/121 (14%)
Query: 141 EEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCNNDEDE 200
E+ DE +++G + +E +P D + D E++ EE D+DDD++ + EDE
Sbjct: 97 EDMDEKEEDEGEEYSEDN----DEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDE 152
Query: 201 VRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDISRNAYSRYNT 260
++ EE + +EE + +ED ++ +++ + E K D + + Y Y+
Sbjct: 153 -------EEEEEEEEEEEEEEENEDHQMNCHNTRIMQDTE------KDDNNNDEYDNYDE 199
Query: 261 I 261
+
Sbjct: 200 L 200
Score = 28.5 bits (62), Expect = 7.0
Identities = 25/116 (21%), Positives = 54/116 (46%), Gaps = 20/116 (17%)
Query: 136 EQPLKEEEDEDRKNKGHQAAEIEWLGFRKPSQADMLHSKHDEEQKVWDEEIDDDDDDNCN 195
E+ +EEE+E+ +N+ HQ + H+ E+ D+++D+ N
Sbjct: 155 EEEEEEEEEEEEENEDHQM------------------NCHNTRIMQDTEKDDNNNDEYDN 196
Query: 196 NDEDEVRVIEFKKKHEEVSQFKEEGDASEDSPLSSASSQAVTPDEQPTLGKKSDIS 251
DE + + K E + ++ ++ +S ++++S D+ LG+KS++S
Sbjct: 197 YDELVAKSLLNLGKIAEDAAYRARTESEMNS--NTSNSLEDDSDKNENLGRKSELS 250
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.126 0.349
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,854,985
Number of Sequences: 37866
Number of extensions: 592400
Number of successful extensions: 5990
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 353
Number of HSP's that attempted gapping in prelim test: 3596
Number of HSP's gapped (non-prelim): 1461
length of query: 284
length of database: 18,247,518
effective HSP length: 101
effective length of query: 183
effective length of database: 14,423,052
effective search space: 2639418516
effective search space used: 2639418516
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.