Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 5730124

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5730124 zinc finger protein 217 [Homo sapiens]
         (1048 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5730124 zinc finger protein 217 [Homo sapiens]                    2164   0.0  
gi|7662092 zinc finger protein 536 [Homo sapiens]                     266   6e-71
gi|7662010 zinc finger protein 516 [Homo sapiens]                     231   4e-60
gi|119120877 zinc finger protein 721 [Homo sapiens]                   129   2e-29
gi|122937217 zinc finger protein 433 [Homo sapiens]                   129   2e-29
gi|62243640 zinc finger protein 107 [Homo sapiens]                    127   5e-29
gi|7706775 zinc finger protein 107 [Homo sapiens]                     127   5e-29
gi|68303809 zinc finger protein 43 [Homo sapiens]                     127   7e-29
gi|117956407 zinc finger protein 568 [Homo sapiens]                   125   2e-28
gi|239753557 PREDICTED: zinc finger protein 852 [Homo sapiens]        124   5e-28
gi|239742001 PREDICTED: zinc finger protein 852 [Homo sapiens]        124   5e-28
gi|47716687 zinc finger protein 167 isoform 1 [Homo sapiens]          123   8e-28
gi|34419633 zinc finger protein 135 [Homo sapiens]                    121   3e-27
gi|32698886 zinc finger protein 595 [Homo sapiens]                    121   4e-27
gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]          119   2e-26
gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]          119   2e-26
gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo ...   119   2e-26
gi|224548994 zinc finger protein 709 isoform b [Homo sapiens]         117   4e-26
gi|22749235 zinc finger protein 709 isoform a [Homo sapiens]          117   4e-26
gi|110626177 zinc finger protein 699 [Homo sapiens]                   115   2e-25
gi|190570172 zinc finger protein 180 [Homo sapiens]                   114   4e-25
gi|55742736 zinc finger protein 700 [Homo sapiens]                    114   4e-25
gi|169165837 PREDICTED: zinc finger protein 852 [Homo sapiens]        113   8e-25
gi|38708324 zinc finger protein 93 [Homo sapiens]                     113   8e-25
gi|222831664 zinc finger protein 184 [Homo sapiens]                   113   1e-24
gi|150170667 zinc finger protein 471 [Homo sapiens]                   112   1e-24
gi|6005976 zinc finger protein 208 [Homo sapiens]                     112   1e-24
gi|111548668 zinc finger protein 676 [Homo sapiens]                   111   4e-24
gi|116256455 zinc finger protein 429 [Homo sapiens]                   109   1e-23
gi|118600985 zinc finger protein 91 [Homo sapiens]                    109   2e-23

>gi|5730124 zinc finger protein 217 [Homo sapiens]
          Length = 1048

 Score = 2164 bits (5607), Expect = 0.0
 Identities = 1048/1048 (100%), Positives = 1048/1048 (100%)

Query: 1    MQSKVTGNMPTQSLLMYMDGPEVIGSSLGSPMEMEDALSMKGTAVVPFRATQEKNVIQIE 60
            MQSKVTGNMPTQSLLMYMDGPEVIGSSLGSPMEMEDALSMKGTAVVPFRATQEKNVIQIE
Sbjct: 1    MQSKVTGNMPTQSLLMYMDGPEVIGSSLGSPMEMEDALSMKGTAVVPFRATQEKNVIQIE 60

Query: 61   GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
            GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE
Sbjct: 61   GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120

Query: 121  KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
            KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG
Sbjct: 121  KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180

Query: 181  KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
            KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK
Sbjct: 181  KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240

Query: 241  KTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQ 300
            KTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQ
Sbjct: 241  KTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQ 300

Query: 301  LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPS 360
            LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPS
Sbjct: 301  LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPS 360

Query: 361  VDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTC 420
            VDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTC
Sbjct: 361  VDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTC 420

Query: 421  SPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFF 480
            SPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFF
Sbjct: 421  SPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFF 480

Query: 481  RSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVAAEVKNDGKNQ 540
            RSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVAAEVKNDGKNQ
Sbjct: 481  RSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVAAEVKNDGKNQ 540

Query: 541  DTEDALLTADSAQTKNLKRFFDGAKDVTGSPPAKQLKEMPSVFQNVLGSAVLSPAHKDTQ 600
            DTEDALLTADSAQTKNLKRFFDGAKDVTGSPPAKQLKEMPSVFQNVLGSAVLSPAHKDTQ
Sbjct: 541  DTEDALLTADSAQTKNLKRFFDGAKDVTGSPPAKQLKEMPSVFQNVLGSAVLSPAHKDTQ 600

Query: 601  DFHKNAADDSADKVNKNPTPAYLDLLKKRSAVETQANNLICRTKADVTPPPDGSTTHNLE 660
            DFHKNAADDSADKVNKNPTPAYLDLLKKRSAVETQANNLICRTKADVTPPPDGSTTHNLE
Sbjct: 601  DFHKNAADDSADKVNKNPTPAYLDLLKKRSAVETQANNLICRTKADVTPPPDGSTTHNLE 660

Query: 661  VSPKEKQTETAADCRYRPSVDCHEKPLNLSVGALHNCPAISLSKSLIPSITCPFCTFKTF 720
            VSPKEKQTETAADCRYRPSVDCHEKPLNLSVGALHNCPAISLSKSLIPSITCPFCTFKTF
Sbjct: 661  VSPKEKQTETAADCRYRPSVDCHEKPLNLSVGALHNCPAISLSKSLIPSITCPFCTFKTF 720

Query: 721  YPEVLMMHQRLEHKYNPDVHKNCRNKSLLRSRRTGCPPALLGKDVPPLSSFCKPKPKSAF 780
            YPEVLMMHQRLEHKYNPDVHKNCRNKSLLRSRRTGCPPALLGKDVPPLSSFCKPKPKSAF
Sbjct: 721  YPEVLMMHQRLEHKYNPDVHKNCRNKSLLRSRRTGCPPALLGKDVPPLSSFCKPKPKSAF 780

Query: 781  PAQSKSLPSAKGKQSPPGPGKAPLTSGIDSSTLAPSNLKSHRPQQNVGVQGAATRQQQSE 840
            PAQSKSLPSAKGKQSPPGPGKAPLTSGIDSSTLAPSNLKSHRPQQNVGVQGAATRQQQSE
Sbjct: 781  PAQSKSLPSAKGKQSPPGPGKAPLTSGIDSSTLAPSNLKSHRPQQNVGVQGAATRQQQSE 840

Query: 841  MFPKTSVSPAPDKTKRPETKLKPLPVAPSQPTLGSSNINGSIDYPAKNDSPWAPPGRDYF 900
            MFPKTSVSPAPDKTKRPETKLKPLPVAPSQPTLGSSNINGSIDYPAKNDSPWAPPGRDYF
Sbjct: 841  MFPKTSVSPAPDKTKRPETKLKPLPVAPSQPTLGSSNINGSIDYPAKNDSPWAPPGRDYF 900

Query: 901  CNRSASNTAAEFGEPLPKRLKSSVVALDVDQPGANYRRGYDLPKYHMVRGITSLLPQDCV 960
            CNRSASNTAAEFGEPLPKRLKSSVVALDVDQPGANYRRGYDLPKYHMVRGITSLLPQDCV
Sbjct: 901  CNRSASNTAAEFGEPLPKRLKSSVVALDVDQPGANYRRGYDLPKYHMVRGITSLLPQDCV 960

Query: 961  YPSQALPPKPRFLSSSEVDSPNVLTVQKPYGGSGPLYTCVPAGSPASSSTLEGKRPVSYQ 1020
            YPSQALPPKPRFLSSSEVDSPNVLTVQKPYGGSGPLYTCVPAGSPASSSTLEGKRPVSYQ
Sbjct: 961  YPSQALPPKPRFLSSSEVDSPNVLTVQKPYGGSGPLYTCVPAGSPASSSTLEGKRPVSYQ 1020

Query: 1021 HLSNSMAQKRNYENFIGNAHYRPNDKKT 1048
            HLSNSMAQKRNYENFIGNAHYRPNDKKT
Sbjct: 1021 HLSNSMAQKRNYENFIGNAHYRPNDKKT 1048


>gi|7662092 zinc finger protein 536 [Homo sapiens]
          Length = 1300

 Score =  266 bits (681), Expect = 6e-71
 Identities = 231/817 (28%), Positives = 355/817 (43%), Gaps = 116/817 (14%)

Query: 50   ATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRP---TLCEPAVLRVEAEYLS 106
            + QE  V    G+    C FC   F   E+L++H+ + H+P   TLC+ A  + E E +S
Sbjct: 262  SVQEDAVAPAAGFR---CTFCKGKFKKREELDRHIRILHKPYKCTLCDFAASQ-EEELIS 317

Query: 107  PLDKSQVRTE------PPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNM 160
             ++K+ +  E      P        NEF CEVCGQ F  A+ ++ HMR HKDSF + C +
Sbjct: 318  HVEKAHITAESAQGQGPNGGGEQSANEFRCEVCGQVFSQAWFLKGHMRKHKDSFEHCCQI 377

Query: 161  CGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMV 220
            CGRRFKEPWFLKNHM+ H  K   ++K     E          + HA  ++ S Y  C+ 
Sbjct: 378  CGRRFKEPWFLKNHMKVHLNKLSVKNKSPSDPEVPVPMGGMSQEAHA--NLYSRYLSCLQ 435

Query: 221  CGFLFPNKESLIEHRKVHTK-------KTAFGTSSAQTDSPQGGMPSS-REDFLQLFNLR 272
             GF+ P+K  L E  +++ K       K A G   +   S   G+P   +   L   NL 
Sbjct: 436  SGFMTPDKAGLSEPSQLYGKGELPMKEKEALGKLLSPISSMAHGVPEGDKHSLLGCLNLV 495

Query: 273  P--KSHPETGKKPVRCIPQLDPFTTFQAWQLATKGK------------------------ 306
            P  KS      +      ++DP  ++QAWQL  +G                         
Sbjct: 496  PPLKSSCIERLQAAAKAAEMDPVNSYQAWQLMARGMAMEHGFLSKEHPLQRNHEDTLANA 555

Query: 307  -VAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHS-----HGEAPS 360
             V   +E +E    G+  +        +  T  GS   L  + +  + S     HG   +
Sbjct: 556  GVLFDKEKREYVLVGADGSKQKMPADLVHSTKVGSQRDLPSKLDPLESSRDFLSHGLNQT 615

Query: 361  VDADPKLPSS-KEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGT 419
            ++ + + P + KEKPT C +CG+ FRTYHQ+V+HSRVHK+DR+   +   + +D R+   
Sbjct: 616  LEYNLQGPGNMKEKPTECPDCGRVFRTYHQVVVHSRVHKRDRKGEEDGLHVGLDERRGSG 675

Query: 420  CSPDLAA------PLDENGAVDRGEGGS--------EDGSEDGLPEGIHLDKNDDGGKIK 465
               +  +      P   N   + G GG         ED      P     D  ++ G+  
Sbjct: 676  SDQESQSVSRSTTPGSSNVTEESGVGGGLSQTGSAQEDSPHPSSPSSS--DIGEEAGRSA 733

Query: 466  HL------------TSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTS 513
             +            ++ ++C YCGK FR++++L +HLR HTGEKPYKC  C+YA  Q  S
Sbjct: 734  GVQQPALLRDRSLGSAMKDCPYCGKTFRTSHHLKVHLRIHTGEKPYKCPHCDYAGTQSAS 793

Query: 514  LRYHLERHHKEKQTDVAAEVKNDGKNQDTEDALLTADS--AQTKNLKRFFDGAK--DVTG 569
            L+YHLERHH+E+Q   A  +     NQD +D + +  S   +   L+  F G    D  G
Sbjct: 794  LKYHLERHHRERQNG-AGPLSGQPPNQDHKDEMSSKASLFIRPDILRGAFKGLPGIDFRG 852

Query: 570  SPPAKQLKE------MPSVFQNVLGSAVLSPAHKDT----QDFHKNAADDSADKVNKNPT 619
             P ++Q           S     + S V S A K T    +  H +    +   +  N  
Sbjct: 853  GPASQQWTSGVLSSGDHSGQATGMSSEVPSDALKGTDLPSKSTHFSEIGRAYQSIVSNGV 912

Query: 620  --PAYLDLLKKRSAVETQANNLICRTKADVTPPPDGSTTHNLEVSPKEKQTETAADCRYR 677
                 L        + +       + KA   PP      H ++   ++   +++     R
Sbjct: 913  NFQGSLQAFMDSFVLSSLKKEKDMKDKALADPP--SMKVHGVDGGEEKPSGKSS----QR 966

Query: 678  PSVDCHEKPLNLSVGA-LHNCPAISLS-KSLIPSITCPFCTFKTFYPEVLMMHQRLEH-- 733
             S     +PL+LSV     + P  S++ +  I    C FC F T   E++ +H +  H  
Sbjct: 967  KSEKSQYEPLDLSVRPDAASLPGSSVTVQDSIAWHGCLFCAFTTSSMELMALHLQANHLG 1026

Query: 734  ----KYNP-DVHKNCRNKSLLRSRRTGCPPALLGKDV 765
                K N   V  NC++++   S+    P     KD+
Sbjct: 1027 KAKRKDNTIGVTVNCKDQAREASKMALLPSLQSNKDL 1063



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 28/49 (57%), Positives = 37/49 (75%)

Query: 473 CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERH 521
           C  CGK FR N  L++H+RTHTGEKP+KC +C++ AAQK +L+ HL  H
Sbjct: 132 CPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 20/55 (36%), Positives = 29/55 (52%)

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K  ++ C +CG+ FR    + +HMRTH     + C  C  R  +   LK H+RTH
Sbjct: 126 KNRKYPCPLCGKRFRFNSILSLHMRTHTGEKPFKCPYCDHRAAQKGNLKIHLRTH 180



 Score = 33.9 bits (76), Expect = 0.82
 Identities = 16/40 (40%), Positives = 23/40 (57%), Gaps = 3/40 (7%)

Query: 142 DVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
           D+E   R ++    Y C +CG+RF+    L  HMRTH G+
Sbjct: 119 DIEDDARKNRK---YPCPLCGKRFRFNSILSLHMRTHTGE 155


>gi|7662010 zinc finger protein 516 [Homo sapiens]
          Length = 1163

 Score =  231 bits (588), Expect = 4e-60
 Identities = 148/436 (33%), Positives = 219/436 (50%), Gaps = 48/436 (11%)

Query: 60  EGYMPLDCMFCSQTFTHSEDLNKHVLMQHRP---TLCEPAVLRVEAEYLSPLDKSQVRTE 116
           E    + C FC   F   +DL  HV   H+P    LC  A LR E+  LS +++  +  +
Sbjct: 169 EAKAAVQCSFCKSQFERKKDLELHVHQAHKPFKCRLCSYATLREES-LLSHIERDHITAQ 227

Query: 117 PPKE-KNCKEN--------EFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKE 167
            P   + C EN        EF CEVCGQ F   + ++ HM+ H+ SF +GC++CGRRFKE
Sbjct: 228 GPGSGEACVENGKPELSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHICGRRFKE 287

Query: 168 PWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPN 227
           PWFLKNHM+ H  K+G++++ +  L+   ATIN VVQ     +  S Y++C  CG LF N
Sbjct: 288 PWFLKNHMKAHGPKTGSKNRPKSELDPI-ATINNVVQEEVIVAGLSLYEVCAKCGNLFTN 346

Query: 228 KESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPS-SREDFLQLFNLRPKSHPET--GKKPV 284
            +SL  H  +H +  A  T +   +  +G  PS +++ FLQ  NLRP +  ++  G +  
Sbjct: 347 LDSLNAHNAIHRRVEASRTRAPAEEGAEG--PSDTKQFFLQCLNLRPSAAGDSCPGTQAG 404

Query: 285 RCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGE--------- 335
           R + +LDP  ++QAWQLAT+GKVA   E  + G        D + +K+  E         
Sbjct: 405 RRVAELDPVNSYQAWQLATRGKVAEPAEYLKYGAWDEALAGDVAFDKDRREYVLVSQEKR 464

Query: 336 -TNKGSCAGLSQEKEKCKHSHGEAPSVDADPK----------LPSSKEKPTHCSECGKAF 384
              + + A     +++       AP+   DP+            + + K + C ECGK F
Sbjct: 465 KREQDAPAAQGPPRKRASGPGDPAPAGHLDPRSAARPNRRAAATTGQGKSSECFECGKIF 524

Query: 385 RTYHQLVLHSRVHKK---------DRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVD 435
           RTYHQ+VLHSRVH++         DR A A   ++S         SP  A    ++    
Sbjct: 525 RTYHQMVLHSRVHRRARRERDSDGDRAARARCGSLSEGDSASQPSSPGSACAAADSPGSG 584

Query: 436 RGEGGSEDGSEDGLPE 451
             +  +ED  E+G PE
Sbjct: 585 LADEAAEDSGEEGAPE 600



 Score = 60.8 bits (146), Expect = 6e-09
 Identities = 24/49 (48%), Positives = 33/49 (67%)

Query: 473 CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERH 521
           C  CGK F     L+ H+R HTGEKPYKC +C++ A+QK +L+ H+  H
Sbjct: 36  CCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSH 84



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 61/317 (19%), Positives = 105/317 (33%), Gaps = 43/317 (13%)

Query: 206 HAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSREDF 265
           H  +   +    C +CG  FP + SL +H + HT +  +        + Q G        
Sbjct: 24  HEVDGDKATCHTCCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRS 83

Query: 266 LQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDND 325
            +   L     PE G+ P   + ++       A    TK   A  + +  + Q       
Sbjct: 84  HRTGTLIQGHEPEAGEAP---LGEMRASEGLDACASPTKSASACNRLLNGASQADGARVL 140

Query: 326 DSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFR 385
           + +S+ + G     S           K + G A +       P   +    CS C   F 
Sbjct: 141 NGASQADSGRVLLRSSK---------KGAEGSACA-------PGEAKAAVQCSFCKSQFE 184

Query: 386 TYHQLVLH-SRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDG 444
               L LH  + HK  +       T+  +          L + ++ +    +G G  E  
Sbjct: 185 RKKDLELHVHQAHKPFKCRLCSYATLREE---------SLLSHIERDHITAQGPGSGEAC 235

Query: 445 SEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFC 504
            E+G PE                     C  CG+ F   ++L  H++ H G   + C  C
Sbjct: 236 VENGKPE--------------LSPGEFPCEVCGQAFSQTWFLKAHMKKHRGSFDHGCHIC 281

Query: 505 EYAAAQKTSLRYHLERH 521
                +   L+ H++ H
Sbjct: 282 GRRFKEPWFLKNHMKAH 298



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 41/170 (24%), Positives = 59/170 (34%), Gaps = 24/170 (14%)

Query: 372 EKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDL---AAPL 428
           EKP  C  C         L +H R H+         P            S  L   A+P 
Sbjct: 59  EKPYKCPYCDHRASQKGNLKIHIRSHRTGTLIQGHEPEAGEAPLGEMRASEGLDACASPT 118

Query: 429 DENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSR----------------E 472
               A +R   G+       +  G       D G++   +S +                +
Sbjct: 119 KSASACNRLLNGASQADGARVLNGA---SQADSGRVLLRSSKKGAEGSACAPGEAKAAVQ 175

Query: 473 CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHH 522
           CS+C   F     L +H+  H   KP+KC  C YA  ++ SL  H+ER H
Sbjct: 176 CSFCKSQFERKKDLELHV--HQAHKPFKCRLCSYATLREESLLSHIERDH 223



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 28/98 (28%), Positives = 42/98 (42%), Gaps = 7/98 (7%)

Query: 129 SCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKL 188
           +C +CG++F     +  HMR H     Y C  C  R  +   LK H+R+H         L
Sbjct: 35  TCCICGKSFPFQSSLSQHMRKHTGEKPYKCPYCDHRASQKGNLKIHIRSHR-----TGTL 89

Query: 189 QQG--LESSPATINEVVQVHAAESISSPYKICMVCGFL 224
            QG   E+  A + E+      ++ +SP K    C  L
Sbjct: 90  IQGHEPEAGEAPLGEMRASEGLDACASPTKSASACNRL 127


>gi|119120877 zinc finger protein 721 [Homo sapiens]
          Length = 923

 Score =  129 bits (323), Expect = 2e-29
 Identities = 127/526 (24%), Positives = 205/526 (38%), Gaps = 80/526 (15%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F HS  LNKH  +    +P  C+     + +       K     E P
Sbjct: 217 GDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVISSSSSFAKHKRIHTGEKP 276

Query: 119 -------------------KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
                              +  +  E  ++CEVCG+ FR + ++ +H R H     Y C 
Sbjct: 277 FKCLECGKAFNISTTLTKHRRIHTGEKPYTCEVCGKAFRQSANLYVHRRIHTGEKPYTCG 336

Query: 160 MCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICM 219
            CG+ F++   L  H R H G+   + +           +N+  ++H  E    PYK C 
Sbjct: 337 ECGKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGE---KPYK-CE 392

Query: 220 VCGFLFPNKESLIEHRKVHTKK---------TAFGTSSAQTDSPQ---GGMPSSRED--- 264
            CG  F +  +L  H+++HT++          AFG S+   +  +   G  P   ++   
Sbjct: 393 ECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNEYKKIHTGDKPYKCKECGK 452

Query: 265 -FLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAW----QLATKGKVAICQEVKESGQE 319
            F+   +L       TGKKP +C       T+  ++    ++ T  K   C E  ++   
Sbjct: 453 AFIHSLHLNKHEKIHTGKKPYKCKQCGKVITSSSSFAKHKRIHTGEKPFECLECGKAFTS 512

Query: 320 GST--------DNDDSSSEKELGETNKGSCAGLSQEK----------EKCKHSHGEAPSV 361
            +T          +   + +  G+  + S       +          E+C  +  ++ ++
Sbjct: 513 STTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYVHRRIHTGEKPYTCEECGKTFRQSANL 572

Query: 362 DADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCS 421
               ++ +  EKP  C ECGKAF  Y  L  H ++H  ++    E             C 
Sbjct: 573 YVHRRIHTG-EKPYKCEECGKAFGRYTDLNQHKKIHTGEKLYKCEE------------CG 619

Query: 422 PDLA--APLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKF 479
            D      L++   +  GE   +   E G       D N    KI     S +C  CGK 
Sbjct: 620 KDFVWYTDLNQQKKIYTGEKPYK-CEECGKAFAPSTDLNQH-TKILTGEQSYKCEECGKA 677

Query: 480 FRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           F  +  LN H + HTGEKPYKCE C  A ++  +L  H   H +EK
Sbjct: 678 FGWSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRVHTREK 723



 Score =  122 bits (306), Expect = 2e-27
 Identities = 118/470 (25%), Positives = 175/470 (37%), Gaps = 80/470 (17%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F HS  LNKH  +    +P  C+             +  S       
Sbjct: 441 GDKPYKCKECGKAFIHSLHLNKHEKIHTGKKPYKCKQC---------GKVITSSSSFAKH 491

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K  +  E  F C  CG+ F  +  +  H R H     Y C +CG+ F++   L  H R H
Sbjct: 492 KRIHTGEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYVHRRIH 551

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+     +         A +    ++H  E    PYK C  CG  F     L +H+K+H
Sbjct: 552 TGEKPYTCEECGKTFRQSANLYVHRRIHTGEK---PYK-CEECGKAFGRYTDLNQHKKIH 607

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
           T +  +                  +DF+   +L  +    TG+KP +C            
Sbjct: 608 TGEKLYKCEECG------------KDFVWYTDLNQQKKIYTGEKPYKC------------ 643

Query: 299 WQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA 358
                          +E G+  +   D +   K L       C       E+C  + G +
Sbjct: 644 ---------------EECGKAFAPSTDLNQHTKILTGEQSYKC-------EECGKAFGWS 681

Query: 359 PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPG 418
            +++   K+ +  EKP  C ECGKAF     L  H RVH +++    E       GR  G
Sbjct: 682 IALNQHKKIHTG-EKPYKCEECGKAFSRSRNLTTHRRVHTREKPYKCEDR-----GRSFG 735

Query: 419 TCSPDLAAPLDENGAVDRGEG---GSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSY 475
                 +  L+E   +  G+      E G      +  HL++++   KI       +C  
Sbjct: 736 W-----STNLNEYKKIHTGDKLYKCKECGKV--FKQSSHLNRHE---KIHTGKKPYKCKE 785

Query: 476 CGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           CGK   S+     H R HTGEKP+KC  C  A    T+L  H   H  EK
Sbjct: 786 CGKVITSSSSFAKHKRIHTGEKPFKCLECGKAFTSSTTLTKHRRIHTGEK 835



 Score =  110 bits (275), Expect = 7e-24
 Identities = 123/498 (24%), Positives = 182/498 (36%), Gaps = 100/498 (20%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKH--VLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C+ C + FT S  L KH  +    +P  CE          +  + +     E P
Sbjct: 497 GEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYTCEVCGKAFRQSAILYVHRRIHTGEKP 556

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
                    ++CE CG+TFR + ++ +H R H     Y C  CG+ F     L  H + H
Sbjct: 557 ---------YTCEECGKTFRQSANLYVHRRIHTGEKPYKCEECGKAFGRYTDLNQHKKIH 607

Query: 179 NGKSGARSKLQQGLESSP-----ATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIE 233
            G+     KL +  E          +N+  +++  E    PYK C  CG  F     L +
Sbjct: 608 TGE-----KLYKCEECGKDFVWYTDLNQQKKIYTGEK---PYK-CEECGKAFAPSTDLNQ 658

Query: 234 HRKVHTKKT---------AFGTSSAQTDSPQ---GGMPSSREDFLQLF----NLRPKSHP 277
           H K+ T +          AFG S A     +   G  P   E+  + F    NL      
Sbjct: 659 HTKILTGEQSYKCEECGKAFGWSIALNQHKKIHTGEKPYKCEECGKAFSRSRNLTTHRRV 718

Query: 278 ETGKKPVRCIPQLDPF---TTFQAWQ-LATKGKVAICQEVKESGQEGSTDNDDSSSEKEL 333
            T +KP +C  +   F   T    ++ + T  K+  C+E  +  ++ S            
Sbjct: 719 HTREKPYKCEDRGRSFGWSTNLNEYKKIHTGDKLYKCKECGKVFKQSS------------ 766

Query: 334 GETNKGSCAGLSQEKEKCKHSHGEAPSVD--ADPKLPSSKEKPTHCSECGKAFRTYHQLV 391
              N+       ++  KCK       S    A  K   + EKP  C ECGKAF +   L 
Sbjct: 767 -HLNRHEKIHTGKKPYKCKECGKVITSSSSFAKHKRIHTGEKPFKCLECGKAFTSSTTLT 825

Query: 392 LHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPE 451
            H R+H                G +P TC                     E G       
Sbjct: 826 KHRRIHT---------------GEKPYTCE--------------------ECGKAFRQSA 850

Query: 452 GIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQK 511
            +++ +    G+  +      C  CGK FR +  L  H + HTGEKPY C  C     Q 
Sbjct: 851 ILYVHRRIHTGEKPYT-----CGECGKTFRQSANLYAHKKIHTGEKPYTCGDCGKTFRQS 905

Query: 512 TSLRYHLERHHKEKQTDV 529
            +L  H + H  +K   V
Sbjct: 906 ANLYAHKKIHTGDKTIQV 923



 Score =  107 bits (268), Expect = 4e-23
 Identities = 114/503 (22%), Positives = 183/503 (36%), Gaps = 90/503 (17%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKS---QVRTEP 117
           G  P  C  C + F  S +L  H  + +R           +A      D++         
Sbjct: 161 GEKPYKCEECGKAFNRSTNLTAHKRIHNRE----------KAYTGEDRDRAFGWSTNLNE 210

Query: 118 PKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRT 177
            K+ +  +  + C+ CG+ F  +  +  H + H     Y C  CG+          H R 
Sbjct: 211 YKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPYKCKECGKVISSSSSFAKHKRI 270

Query: 178 HNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKV 237
           H G+   +        +   T+ +  ++H  E    PY  C VCG  F    +L  HR++
Sbjct: 271 HTGEKPFKCLECGKAFNISTTLTKHRRIHTGE---KPY-TCEVCGKAFRQSANLYVHRRI 326

Query: 238 HTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQ 297
           HT +  +                  + F Q  NL       TG+KP +C      F  + 
Sbjct: 327 HTGEKPYTCGEC------------GKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYT 374

Query: 298 AW----QLATKGKVAICQEVKE---SGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEK 350
           A     ++ T  K   C+E  +   S    +      + EK     ++G   GLS    +
Sbjct: 375 ALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTREKPYTCEDRGRAFGLSTNLNE 434

Query: 351 CKHSH-GEAP--------------SVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSR 395
            K  H G+ P               ++   K+ + K KP  C +CGK   +      H R
Sbjct: 435 YKKIHTGDKPYKCKECGKAFIHSLHLNKHEKIHTGK-KPYKCKQCGKVITSSSSFAKHKR 493

Query: 396 VHKKDR--------RAGAESPTMSV-----DGRQPGTCSPDLAAPLDENGAVDRGEGGSE 442
           +H  ++        +A   S T++       G +P TC  ++        A+        
Sbjct: 494 IHTGEKPFECLECGKAFTSSTTLTKHRRIHTGEKPYTC--EVCGKAFRQSAI-------- 543

Query: 443 DGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCE 502
                     +++ +    G+  +      C  CGK FR +  L +H R HTGEKPYKCE
Sbjct: 544 ----------LYVHRRIHTGEKPY-----TCEECGKTFRQSANLYVHRRIHTGEKPYKCE 588

Query: 503 FCEYAAAQKTSLRYHLERHHKEK 525
            C  A  + T L  H + H  EK
Sbjct: 589 ECGKAFGRYTDLNQHKKIHTGEK 611



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 98/421 (23%), Positives = 148/421 (35%), Gaps = 97/421 (23%)

Query: 122 NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
           N +   F C    + F    +       H     + CN CG+ F++   L  H   H G+
Sbjct: 75  NTQSKIFQCNARVKVFSKFANSNKDKTRHTGEKHFKCNECGKSFQKFSDLTQHKGIHAGE 134

Query: 182 SGARSKLQQGLESSPAT-INEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
                + ++G +    T +N+  ++H  E    PYK C  CG  F    +L  H+++H +
Sbjct: 135 KPYTCE-ERGKDFGWYTDLNQHKKIHTGE---KPYK-CEECGKAFNRSTNLTAHKRIHNR 189

Query: 241 K---------TAFGTSSAQTDSPQ---GGMPSSRED----FLQLFNLRPKSHPETGKKPV 284
           +          AFG S+   +  +   G  P   ++    F+   +L       TG+KP 
Sbjct: 190 EKAYTGEDRDRAFGWSTNLNEYKKIHTGDKPYKCKECGKAFMHSSHLNKHEKIHTGEKPY 249

Query: 285 RCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGL 344
           +C                       C +V  S    +      + EK       G    +
Sbjct: 250 KC---------------------KECGKVISSSSSFAKHKRIHTGEKPFKCLECGKAFNI 288

Query: 345 SQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAG 404
           S    K +  H              + EKP  C  CGKAFR    L +H R+H       
Sbjct: 289 STTLTKHRRIH--------------TGEKPYTCEVCGKAFRQSANLYVHRRIH------- 327

Query: 405 AESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKI 464
                    G +P TC                     E G        +++ +    G+ 
Sbjct: 328 --------TGEKPYTC--------------------GECGKTFRQSANLYVHRRIHTGEK 359

Query: 465 KHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKE 524
            +     +C  CGK F     LN H + HTGEKPYKCE C  A    T+L  H   H +E
Sbjct: 360 PY-----KCEDCGKAFGRYTALNQHKKIHTGEKPYKCEECGKAFNSSTNLTAHKRIHTRE 414

Query: 525 K 525
           K
Sbjct: 415 K 415



 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 96/409 (23%), Positives = 133/409 (32%), Gaps = 123/409 (30%)

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K ++  E  F C  CG++F+   D+  H   H     Y C   G+ F     L  H + H
Sbjct: 100 KTRHTGEKHFKCNECGKSFQKFSDLTQHKGIHAGEKPYTCEERGKDFGWYTDLNQHKKIH 159

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+                                PYK C  CG  F    +L  H+++H
Sbjct: 160 TGEK-------------------------------PYK-CEECGKAFNRSTNLTAHKRIH 187

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
            ++ A+  +    D   G             NL       TG KP +C            
Sbjct: 188 NREKAY--TGEDRDRAFGWST----------NLNEYKKIHTGDKPYKC------------ 223

Query: 299 WQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHG-- 356
                          KE G+          +       NK       ++  KCK      
Sbjct: 224 ---------------KECGK----------AFMHSSHLNKHEKIHTGEKPYKCKECGKVI 258

Query: 357 EAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQ 416
            + S  A  K   + EKP  C ECGKAF     L  H R+H                G +
Sbjct: 259 SSSSSFAKHKRIHTGEKPFKCLECGKAFNISTTLTKHRRIH---------------TGEK 303

Query: 417 PGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYC 476
           P TC                       G        +++ +    G+  +      C  C
Sbjct: 304 PYTC--------------------EVCGKAFRQSANLYVHRRIHTGEKPY-----TCGEC 338

Query: 477 GKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           GK FR +  L +H R HTGEKPYKCE C  A  + T+L  H + H  EK
Sbjct: 339 GKTFRQSANLYVHRRIHTGEKPYKCEDCGKAFGRYTALNQHKKIHTGEK 387


>gi|122937217 zinc finger protein 433 [Homo sapiens]
          Length = 673

 Score =  129 bits (323), Expect = 2e-29
 Identities = 123/482 (25%), Positives = 177/482 (36%), Gaps = 56/482 (11%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+HS  L  H       +P  C                 S       
Sbjct: 222 GEKPYQCKQCGKAFSHSSSLRIHERTHTGEKPYKCNEC---------GKAFHSSTCLHAH 272

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K  +  E  + C+ CG+ F  +   +IH RTH     Y C  CG+ FK P  ++ H RTH
Sbjct: 273 KRTHTGEKPYECKQCGKAFSSSHSFQIHERTHTGEKPYECKECGKAFKCPSSVRRHERTH 332

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
           + K     K    + S   +    + +H  E        C +CG  F +  SL  H K H
Sbjct: 333 SRKKPYECKHCGKVLSYLTSFQNHLGMHTGEISHK----CKICGKAFYSPSSLQTHEKTH 388

Query: 239 TKKT---------AFGTSSA---QTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKK 282
           T +          AF +SS+      +  G  P   +   + F     L+      TG+K
Sbjct: 389 TGEKPYKCNQCGKAFNSSSSFRYHERTHTGEKPYECKQCGKAFRSASLLQTHGRTHTGEK 448

Query: 283 PVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCA 342
           P  C     PF+ F  +Q+  +         +E   E        S         +    
Sbjct: 449 PYACKECGKPFSNFSFFQIHER------MHREEKPYECKGYGKTFSLPSLFHRHERTHTG 502

Query: 343 GLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRR 402
           G + E ++C  S   + S     +  +  EKP  C +CGKAFR+  QL +H R H     
Sbjct: 503 GKTYECKQCGRSFNCSSSFRYHGRTHTG-EKPYECKQCGKAFRSASQLQIHGRTH----- 556

Query: 403 AGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSED---GSEDGLPEGIHLDKND 459
            G +       G+  G+     A+ L  +G    GE   E    G   G    + +    
Sbjct: 557 TGEKPYECKQCGKAFGS-----ASHLQMHGRTHTGEKPYECKQCGKSFGCASRLQMHGRT 611

Query: 460 DGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLE 519
             G+  +     +C  CGK F     L  H RTHTGEKPYKC  C       + L+ H  
Sbjct: 612 HTGEKPY-----KCKQCGKAFGCPSNLRRHGRTHTGEKPYKCNQCGKVFRCSSQLQVHGR 666

Query: 520 RH 521
            H
Sbjct: 667 AH 668



 Score =  114 bits (286), Expect = 4e-25
 Identities = 112/464 (24%), Positives = 172/464 (37%), Gaps = 52/464 (11%)

Query: 67  CMFCSQTFTHSEDLNKHVLMQ-----HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEK 121
           C  C +TF    +L +H +M      ++   C  A++ +    +             K  
Sbjct: 172 CEECGKTFISHSNLQRHRIMHRGDGPYKCKFCGKALMFLSLYLIH------------KRT 219

Query: 122 NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
           +  E  + C+ CG+ F  +  + IH RTH     Y CN CG+ F     L  H RTH G+
Sbjct: 220 HTGEKPYQCKQCGKAFSHSSSLRIHERTHTGEKPYKCNECGKAFHSSTCLHAHKRTHTGE 279

Query: 182 SGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKK 241
                K      SS  +     + H  E    PY+ C  CG  F    S+  H + H++K
Sbjct: 280 KPYECKQCGKAFSSSHSFQIHERTHTGE---KPYE-CKECGKAFKCPSSVRRHERTHSRK 335

Query: 242 TAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQL 301
             +           G + S    F     +       TG+   +C  ++     +    L
Sbjct: 336 KPYECKHC------GKVLSYLTSFQNHLGM------HTGEISHKC--KICGKAFYSPSSL 381

Query: 302 ATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSV 361
            T  K    ++  +  Q G   N  SSS +    T+ G       E ++C  +   A  +
Sbjct: 382 QTHEKTHTGEKPYKCNQCGKAFN-SSSSFRYHERTHTGE---KPYECKQCGKAFRSASLL 437

Query: 362 DADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCS 421
               +  +  EKP  C ECGK F  +    +H R+H++++            G       
Sbjct: 438 QTHGRTHTG-EKPYACKECGKPFSNFSFFQIHERMHREEK-------PYECKGYGKTFSL 489

Query: 422 PDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFR 481
           P L    +      +     + G                 G+  +     EC  CGK FR
Sbjct: 490 PSLFHRHERTHTGGKTYECKQCGRSFNCSSSFRYHGRTHTGEKPY-----ECKQCGKAFR 544

Query: 482 SNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           S   L IH RTHTGEKPY+C+ C  A    + L+ H   H  EK
Sbjct: 545 SASQLQIHGRTHTGEKPYECKQCGKAFGSASHLQMHGRTHTGEK 588



 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 111/462 (24%), Positives = 161/462 (34%), Gaps = 101/462 (21%)

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRF------------------- 165
           +  + C+ C + F     V+ H R H     Y C  CG+ F                   
Sbjct: 139 QKPYKCKYCKKPFNCLSSVQTHERAHSGRKLYVCEECGKTFISHSNLQRHRIMHRGDGPY 198

Query: 166 ------KEPWFLK---NHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYK 216
                 K   FL     H RTH G+   + K      S  +++    + H  E    PYK
Sbjct: 199 KCKFCGKALMFLSLYLIHKRTHTGEKPYQCKQCGKAFSHSSSLRIHERTHTGE---KPYK 255

Query: 217 ICMVCGFLFPNKESLIEHRKVHTKKTAF-----GTSSAQTDSPQ-------GGMPSSRED 264
            C  CG  F +   L  H++ HT +  +     G + + + S Q       G  P   ++
Sbjct: 256 -CNECGKAFHSSTCLHAHKRTHTGEKPYECKQCGKAFSSSHSFQIHERTHTGEKPYECKE 314

Query: 265 FLQLF----NLRPKSHPETGKKPVRCI---PQLDPFTTFQAWQLATKGKVA----ICQEV 313
             + F    ++R      + KKP  C      L   T+FQ       G+++    IC + 
Sbjct: 315 CGKAFKCPSSVRRHERTHSRKKPYECKHCGKVLSYLTSFQNHLGMHTGEISHKCKICGKA 374

Query: 314 KESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEK 373
             S     T     + EK       G     S      + +H              + EK
Sbjct: 375 FYSPSSLQTHEKTHTGEKPYKCNQCGKAFNSSSSFRYHERTH--------------TGEK 420

Query: 374 PTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDE--- 430
           P  C +CGKAFR+   L  H R H                G +P  C  +   P      
Sbjct: 421 PYECKQCGKAFRSASLLQTHGRTH---------------TGEKPYACK-ECGKPFSNFSF 464

Query: 431 ---NGAVDRGEGGSE---DGSEDGLPEGIHL-DKNDDGGKIKHLTSSRECSYCGKFFRSN 483
              +  + R E   E    G    LP   H  ++   GGK      + EC  CG+ F  +
Sbjct: 465 FQIHERMHREEKPYECKGYGKTFSLPSLFHRHERTHTGGK------TYECKQCGRSFNCS 518

Query: 484 YYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
                H RTHTGEKPY+C+ C  A    + L+ H   H  EK
Sbjct: 519 SSFRYHGRTHTGEKPYECKQCGKAFRSASQLQIHGRTHTGEK 560



 Score = 35.0 bits (79), Expect = 0.37
 Identities = 29/100 (29%), Positives = 46/100 (46%), Gaps = 13/100 (13%)

Query: 445 SEDGLPEGIHLDKNDDGGKIKHLTSSREC--SYCGKFFRSNYYLNIHLRTHTG------- 495
           S++G   G  L +  D    K  T  + C  S  G+   ++  LN H+R  TG       
Sbjct: 76  SKEGHQHGEILTQVPDDMLKKTTTGVKSCESSVYGEVGSAHSSLNRHIRDDTGHKAYEYQ 135

Query: 496 ---EKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVAAE 532
              +KPYKC++C+      +S++ H ER H  ++  V  E
Sbjct: 136 EYGQKPYKCKYCKKPFNCLSSVQTH-ERAHSGRKLYVCEE 174


>gi|62243640 zinc finger protein 107 [Homo sapiens]
          Length = 783

 Score =  127 bits (319), Expect = 5e-29
 Identities = 127/491 (25%), Positives = 199/491 (40%), Gaps = 78/491 (15%)

Query: 67  CMFCSQTFTHSEDLNKH--VLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCK 124
           C  C + F  S  L  H  +LM+ +P  CE    +V  ++ S L + ++     K   CK
Sbjct: 302 CEECDKAFNRSLKLTAHKKILMEEKPYKCEECG-KVFNQF-STLTRHKIIHTGEKPYKCK 359

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E       CG+ F  + ++  H + H    +Y C  CG+ F +   L NH + ++G+   
Sbjct: 360 E-------CGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPY 412

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           + +      +  +T+    ++H  E    PYK C  C   F    +L EH+K+HT     
Sbjct: 413 KCEECGKAFNRSSTLTRHKKIHTGEK---PYK-CEECDRAFSQSSNLTEHKKIHT----- 463

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDPFTTFQAWQ 300
                      G  P   E+  + FN    L       TG+KP +C      F   Q++Q
Sbjct: 464 -----------GEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFN--QSYQ 510

Query: 301 LA------TKGKVAICQEVKESGQEGSTDNDDS---SSEKELGETNKGSCAGLSQE--KE 349
           L       TK K+  C+E  ++ ++ S         + EK       G     S     +
Sbjct: 511 LTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQ 570

Query: 350 KCKHS---------HGEAPSVDAD---PKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
           K  H+         HG+A ++ ++    K+  + EKP  C ECGKA+  +  L +H R+H
Sbjct: 571 KIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIH 630

Query: 398 KKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGG---SEDGSEDGLPEGIH 454
                   E P    +  +   CS    + L+ +  +  GE      E G    L   + 
Sbjct: 631 T------GEKPYQCAECGKAFNCS----STLNRHKIIHTGEKPYKCKECGKAFNLSSTLT 680

Query: 455 LDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSL 514
             K    G+  +     +C  CGK F  +  L  H + HT EKPYKCE C  +  Q +SL
Sbjct: 681 AHKKIHTGEKPY-----KCEECGKAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSL 735

Query: 515 RYHLERHHKEK 525
             H   H  EK
Sbjct: 736 NIHKIIHTGEK 746



 Score =  107 bits (266), Expect = 8e-23
 Identities = 135/587 (22%), Positives = 209/587 (35%), Gaps = 122/587 (20%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLM--QHRPTLCEPAVLRV-EAEYLSPLDKSQVRTEP 117
           G  P  C  C + F  S  L +H ++  + +P  CE       +A +L+         +P
Sbjct: 156 GEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKP 215

Query: 118 PKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
            K + C                   EN + C+ CG+ F +  ++  H R H     Y C 
Sbjct: 216 YKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCK 275

Query: 160 MCGRRFKEPWFLKNHMRTHNG-----------------KSGARSKLQQGLESSPATINEV 202
            CGR F     L    + H G                 K  A  K+   +E  P    E 
Sbjct: 276 ECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKIL--MEEKPYKCEEC 333

Query: 203 VQVHAAESISSPYKI---------CMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDS 253
            +V    S  + +KI         C  CG  F    +L EH+K+HT + ++         
Sbjct: 334 GKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECG--- 390

Query: 254 PQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPF----TTFQAWQLATKGKVAI 309
                    + F Q  NL       +G+KP +C      F    T  +  ++ T  K   
Sbjct: 391 ---------KAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYK 441

Query: 310 CQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPS 369
           C+E   +  + S           L E  K        + E+C  +     ++    ++ +
Sbjct: 442 CEECDRAFSQSSN----------LTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHT 491

Query: 370 SKEKPTHCSECGKAFRTYHQLVLHSRVHKKDR--------RAGAESPTMSVD-----GRQ 416
             EKP  C ECGKAF   +QL  H  VH K++        +A  +S   ++      G +
Sbjct: 492 G-EKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEK 550

Query: 417 PGTCSP-----DLAAPLDENGAVDRGEG---GSEDGSEDGLPEGIHLDKNDDGGKIKH-- 466
           P  C       + ++ L     +  GE      E G    L   I   K    G+  H  
Sbjct: 551 PYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKC 610

Query: 467 ------------LTSSR---------ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCE 505
                       LT  +         +C+ CGK F  +  LN H   HTGEKPYKC+ C 
Sbjct: 611 EECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECG 670

Query: 506 YAAAQKTSLRYHLERHHKEK--QTDVAAEVKNDGKNQDTEDALLTAD 550
            A    ++L  H + H  EK  + +   +  N   N  T   + T++
Sbjct: 671 KAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSE 717



 Score =  102 bits (254), Expect = 2e-21
 Identities = 104/418 (24%), Positives = 159/418 (38%), Gaps = 57/418 (13%)

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWF--LKNHMR 176
           K ++     F C+ C ++F V   +  H R H    +Y C  CG+ F   WF  L  H R
Sbjct: 95  KRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFN--WFSTLTKHKR 152

Query: 177 THNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRK 236
            H G+   + +      +  + +     +H  E    P K C  CG  F     L  H+ 
Sbjct: 153 IHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEE---KPNK-CEECGKAFKQASHLTIHKI 208

Query: 237 VHTKKTAFGTSSAQTDSPQGGMPSSRED----FLQLFNLRPKSHPETGKKPVRCIPQLDP 292
           +HT                G  P   E+    F Q  +L  +    TG+   +C      
Sbjct: 209 IHT----------------GEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKA 252

Query: 293 FTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCK 352
           F  F    L    ++   ++  +  + G   N  S+  K+     K    G   + E+C 
Sbjct: 253 FNLFS--NLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQ----EKIHTGGKLNKCEECD 306

Query: 353 HSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSV 412
            +   +  + A  K+   +EKP  C ECGK F  +  L  H  +H               
Sbjct: 307 KAFNRSLKLTAHKKI-LMEEKPYKCEECGKVFNQFSTLTRHKIIH--------------- 350

Query: 413 DGRQPGTCSP-----DLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHL 467
            G +P  C       + ++ L E+  +   E  S    E G     H +  +   KI   
Sbjct: 351 TGEKPYKCKECGKAFNQSSNLTEHKKIHTAE-KSYKCEECGKAFNQHSNLINH-RKIYSG 408

Query: 468 TSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
               +C  CGK F  +  L  H + HTGEKPYKCE C+ A +Q ++L  H + H  EK
Sbjct: 409 EKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEK 466



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 472 ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK--QTDV 529
           +C  CGK F  +  L  H   HT EKP KCE C  A  Q + L  H   H  EK  + + 
Sbjct: 161 KCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEE 220

Query: 530 AAEVKNDGKNQDTEDALLTADS 551
             +V +   +  T+  L T ++
Sbjct: 221 CGKVFSQSSHLTTQKILHTGEN 242


>gi|7706775 zinc finger protein 107 [Homo sapiens]
          Length = 783

 Score =  127 bits (319), Expect = 5e-29
 Identities = 127/491 (25%), Positives = 199/491 (40%), Gaps = 78/491 (15%)

Query: 67  CMFCSQTFTHSEDLNKH--VLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCK 124
           C  C + F  S  L  H  +LM+ +P  CE    +V  ++ S L + ++     K   CK
Sbjct: 302 CEECDKAFNRSLKLTAHKKILMEEKPYKCEECG-KVFNQF-STLTRHKIIHTGEKPYKCK 359

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E       CG+ F  + ++  H + H    +Y C  CG+ F +   L NH + ++G+   
Sbjct: 360 E-------CGKAFNQSSNLTEHKKIHTAEKSYKCEECGKAFNQHSNLINHRKIYSGEKPY 412

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           + +      +  +T+    ++H  E    PYK C  C   F    +L EH+K+HT     
Sbjct: 413 KCEECGKAFNRSSTLTRHKKIHTGEK---PYK-CEECDRAFSQSSNLTEHKKIHT----- 463

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDPFTTFQAWQ 300
                      G  P   E+  + FN    L       TG+KP +C      F   Q++Q
Sbjct: 464 -----------GEKPYKCEECGKAFNRFSTLTKHKRIHTGEKPYKCEECGKAFN--QSYQ 510

Query: 301 LA------TKGKVAICQEVKESGQEGSTDNDDS---SSEKELGETNKGSCAGLSQE--KE 349
           L       TK K+  C+E  ++ ++ S         + EK       G     S     +
Sbjct: 511 LTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEKPYKCEEHGKVFNQSSNLTTQ 570

Query: 350 KCKHS---------HGEAPSVDAD---PKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
           K  H+         HG+A ++ ++    K+  + EKP  C ECGKA+  +  L +H R+H
Sbjct: 571 KIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKCEECGKAYNRFSNLTIHKRIH 630

Query: 398 KKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGG---SEDGSEDGLPEGIH 454
                   E P    +  +   CS    + L+ +  +  GE      E G    L   + 
Sbjct: 631 T------GEKPYQCAECGKAFNCS----STLNRHKIIHTGEKPYKCKECGKAFNLSSTLT 680

Query: 455 LDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSL 514
             K    G+  +     +C  CGK F  +  L  H + HT EKPYKCE C  +  Q +SL
Sbjct: 681 AHKKIHTGEKPY-----KCEECGKAFNQSSNLTTHKKIHTSEKPYKCEECGKSFNQFSSL 735

Query: 515 RYHLERHHKEK 525
             H   H  EK
Sbjct: 736 NIHKIIHTGEK 746



 Score =  107 bits (266), Expect = 8e-23
 Identities = 135/587 (22%), Positives = 209/587 (35%), Gaps = 122/587 (20%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLM--QHRPTLCEPAVLRV-EAEYLSPLDKSQVRTEP 117
           G  P  C  C + F  S  L +H ++  + +P  CE       +A +L+         +P
Sbjct: 156 GEKPYKCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKP 215

Query: 118 PKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
            K + C                   EN + C+ CG+ F +  ++  H R H     Y C 
Sbjct: 216 YKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKAFNLFSNLTNHKRIHAGEKPYKCK 275

Query: 160 MCGRRFKEPWFLKNHMRTHNG-----------------KSGARSKLQQGLESSPATINEV 202
            CGR F     L    + H G                 K  A  K+   +E  P    E 
Sbjct: 276 ECGRAFNISSNLNKQEKIHTGGKLNKCEECDKAFNRSLKLTAHKKIL--MEEKPYKCEEC 333

Query: 203 VQVHAAESISSPYKI---------CMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDS 253
            +V    S  + +KI         C  CG  F    +L EH+K+HT + ++         
Sbjct: 334 GKVFNQFSTLTRHKIIHTGEKPYKCKECGKAFNQSSNLTEHKKIHTAEKSYKCEECG--- 390

Query: 254 PQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPF----TTFQAWQLATKGKVAI 309
                    + F Q  NL       +G+KP +C      F    T  +  ++ T  K   
Sbjct: 391 ---------KAFNQHSNLINHRKIYSGEKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYK 441

Query: 310 CQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPS 369
           C+E   +  + S           L E  K        + E+C  +     ++    ++ +
Sbjct: 442 CEECDRAFSQSSN----------LTEHKKIHTGEKPYKCEECGKAFNRFSTLTKHKRIHT 491

Query: 370 SKEKPTHCSECGKAFRTYHQLVLHSRVHKKDR--------RAGAESPTMSVD-----GRQ 416
             EKP  C ECGKAF   +QL  H  VH K++        +A  +S   ++      G +
Sbjct: 492 G-EKPYKCEECGKAFNQSYQLTRHKIVHTKEKLNKCEEFGKAFKQSSHRTIHKIIHTGEK 550

Query: 417 PGTCSP-----DLAAPLDENGAVDRGEG---GSEDGSEDGLPEGIHLDKNDDGGKIKH-- 466
           P  C       + ++ L     +  GE      E G    L   I   K    G+  H  
Sbjct: 551 PYKCEEHGKVFNQSSNLTTQKIIHTGENLYKFEEHGKAFNLFSNITNHKIIYTGEKPHKC 610

Query: 467 ------------LTSSR---------ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCE 505
                       LT  +         +C+ CGK F  +  LN H   HTGEKPYKC+ C 
Sbjct: 611 EECGKAYNRFSNLTIHKRIHTGEKPYQCAECGKAFNCSSTLNRHKIIHTGEKPYKCKECG 670

Query: 506 YAAAQKTSLRYHLERHHKEK--QTDVAAEVKNDGKNQDTEDALLTAD 550
            A    ++L  H + H  EK  + +   +  N   N  T   + T++
Sbjct: 671 KAFNLSSTLTAHKKIHTGEKPYKCEECGKAFNQSSNLTTHKKIHTSE 717



 Score =  102 bits (254), Expect = 2e-21
 Identities = 104/418 (24%), Positives = 159/418 (38%), Gaps = 57/418 (13%)

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWF--LKNHMR 176
           K ++     F C+ C ++F V   +  H R H    +Y C  CG+ F   WF  L  H R
Sbjct: 95  KRRHTGNKHFKCKECSKSFCVLSQLTQHRRIHTRVNSYKCEECGKAFN--WFSTLTKHKR 152

Query: 177 THNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRK 236
            H G+   + +      +  + +     +H  E    P K C  CG  F     L  H+ 
Sbjct: 153 IHTGEKPYKCEECGKAFNQSSQLTRHKIIHTEE---KPNK-CEECGKAFKQASHLTIHKI 208

Query: 237 VHTKKTAFGTSSAQTDSPQGGMPSSRED----FLQLFNLRPKSHPETGKKPVRCIPQLDP 292
           +HT                G  P   E+    F Q  +L  +    TG+   +C      
Sbjct: 209 IHT----------------GEKPYKYEECGKVFSQSSHLTTQKILHTGENLYKCKECGKA 252

Query: 293 FTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCK 352
           F  F    L    ++   ++  +  + G   N  S+  K+     K    G   + E+C 
Sbjct: 253 FNLFS--NLTNHKRIHAGEKPYKCKECGRAFNISSNLNKQ----EKIHTGGKLNKCEECD 306

Query: 353 HSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSV 412
            +   +  + A  K+   +EKP  C ECGK F  +  L  H  +H               
Sbjct: 307 KAFNRSLKLTAHKKI-LMEEKPYKCEECGKVFNQFSTLTRHKIIH--------------- 350

Query: 413 DGRQPGTCSP-----DLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHL 467
            G +P  C       + ++ L E+  +   E  S    E G     H +  +   KI   
Sbjct: 351 TGEKPYKCKECGKAFNQSSNLTEHKKIHTAE-KSYKCEECGKAFNQHSNLINH-RKIYSG 408

Query: 468 TSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
               +C  CGK F  +  L  H + HTGEKPYKCE C+ A +Q ++L  H + H  EK
Sbjct: 409 EKPYKCEECGKAFNRSSTLTRHKKIHTGEKPYKCEECDRAFSQSSNLTEHKKIHTGEK 466



 Score = 43.9 bits (102), Expect = 8e-04
 Identities = 27/82 (32%), Positives = 38/82 (46%), Gaps = 2/82 (2%)

Query: 472 ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK--QTDV 529
           +C  CGK F  +  L  H   HT EKP KCE C  A  Q + L  H   H  EK  + + 
Sbjct: 161 KCEECGKAFNQSSQLTRHKIIHTEEKPNKCEECGKAFKQASHLTIHKIIHTGEKPYKYEE 220

Query: 530 AAEVKNDGKNQDTEDALLTADS 551
             +V +   +  T+  L T ++
Sbjct: 221 CGKVFSQSSHLTTQKILHTGEN 242


>gi|68303809 zinc finger protein 43 [Homo sapiens]
          Length = 809

 Score =  127 bits (318), Expect = 7e-29
 Identities = 126/492 (25%), Positives = 197/492 (40%), Gaps = 68/492 (13%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ-----HRPTLCEPAVLRVEAEYLSPLDKSQVRT 115
           G  P  C  C + F    +L  H  +      ++ T C  A  R      S L K     
Sbjct: 338 GEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRS-----SNLTKH---- 388

Query: 116 EPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHM 175
              K+ + ++  + CE CG+ F+ +  +  H  TH     Y C  CG+ F  P  L  H 
Sbjct: 389 ---KKIHTEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHN 445

Query: 176 RTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHR 235
           R H G+   + ++     +  + +    ++H AE    PYK C  CG  F    +L +H+
Sbjct: 446 RIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHTAE---KPYK-CEECGKAFSRSSNLTKHK 501

Query: 236 KVHTKK---------TAFGTSSAQTD---SPQGGMPSSREDFLQLFN----LRPKSHPET 279
           K+H +K          AF  SS  T+   +  G  P   E+  + FN    L       T
Sbjct: 502 KIHIEKKPYKCEECGKAFKWSSKLTEHKITHTGEKPYKCEECGKAFNHFSILTKHKRIHT 561

Query: 280 GKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKG 339
           G+KP +C      FT  Q+  L T  K+   ++  +  + G      S+    L    K 
Sbjct: 562 GEKPYKCEECGKAFT--QSSNLTTHKKIHTGEKFYKCEECGKAFTQSSN----LTTHKKI 615

Query: 340 SCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKK 399
              G   + E+C  +  +  ++    K+  ++EKP  C ECGKAF+    L  H  +H  
Sbjct: 616 HTGGKPYKCEECGKAFNQFSTL-TKHKIIHTEEKPYKCEECGKAFKWSSTLTKHKIIH-- 672

Query: 400 DRRAGAESPTMSVDGRQPGTCSP-----DLAAPLDENGAVDRGEGGSEDGSEDGLPEGIH 454
                         G +P  C        L++ L  +  +  GE   +    +   +  +
Sbjct: 673 -------------TGEKPYKCEECGKAFKLSSTLSTHKIIHTGE---KPYKCEKCGKAFN 716

Query: 455 LDKN-DDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTS 513
              N  +  KI       +C  CGK F  + +LN H R HT E+PYKC+ C  A  Q ++
Sbjct: 717 RSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQYSN 776

Query: 514 LRYHLERHHKEK 525
           L  H + H  EK
Sbjct: 777 LTTHNKIHTGEK 788



 Score =  115 bits (289), Expect = 2e-25
 Identities = 124/486 (25%), Positives = 181/486 (37%), Gaps = 84/486 (17%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTL--CEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F  S  L  H     R  L  CE        E     +KS + T   
Sbjct: 226 GEKPYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCE--------ECGKAFNKSSILTTH- 276

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K     E  + C+ C + F  + ++  H + H     Y C  CG+ F  P  L  H R H
Sbjct: 277 KIIRTGEKFYKCKECAKAFNQSSNLTEHKKIHPGEKPYKCEECGKAFNWPSTLTKHKRIH 336

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+     +      +  + +    ++H AE     YK C  CG  F    +L +H+K+H
Sbjct: 337 TGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKF---YK-CTECGEAFSRSSNLTKHKKIH 392

Query: 239 TKK---------TAFGTSSAQTD---SPQGGMPSSREDFLQLFN----LRPKSHPETGKK 282
           T+K          AF  SS  T+   +  G  P   E+  + FN    L   +   TG+K
Sbjct: 393 TEKKPYKCEECGKAFKWSSKLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEK 452

Query: 283 PVRCIPQLDPFTTFQAWQLATKGKVAICQ---EVKESGQEGSTDNDDSSSEKELGETNKG 339
           P +C      F  F    L T  ++   +   + +E G+  S  ++ +  +K   E    
Sbjct: 453 PYKCEVCGKAFNQFS--NLTTHKRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPY 510

Query: 340 SCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKK 399
            C       E+C  +   +  +  + K+  + EKP  C ECGKAF  +  L  H R+H  
Sbjct: 511 KC-------EECGKAFKWSSKL-TEHKITHTGEKPYKCEECGKAFNHFSILTKHKRIH-- 560

Query: 400 DRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKND 459
                         G +P  C                     E G        +   K  
Sbjct: 561 -------------TGEKPYKC--------------------EECGKAFTQSSNLTTHK-- 585

Query: 460 DGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLE 519
              KI       +C  CGK F  +  L  H + HTG KPYKCE C  A  Q ++L  H  
Sbjct: 586 ---KIHTGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKI 642

Query: 520 RHHKEK 525
            H +EK
Sbjct: 643 IHTEEK 648



 Score =  104 bits (260), Expect = 4e-22
 Identities = 115/470 (24%), Positives = 175/470 (37%), Gaps = 64/470 (13%)

Query: 67  CMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCKEN 126
           C  C ++F     L +H ++  R   C+           S + K        K  N  E 
Sbjct: 176 CKECGKSFCMLPHLAQHKIIHTRVNFCKCEKCGKAFNCPSIITKH-------KRINTGEK 228

Query: 127 EFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARS 186
            ++CE CG+ F  +  +  H + +     Y C  CG+ F +   L  H     G+   + 
Sbjct: 229 PYTCEECGKVFNWSSRLTTHKKNYTRYKLYKCEECGKAFNKSSILTTHKIIRTGEKFYKC 288

Query: 187 KLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGT 246
           K      +  + + E  ++H  E    PYK C  CG  F    +L +H+++HT +  +  
Sbjct: 289 KECAKAFNQSSNLTEHKKIHPGE---KPYK-CEECGKAFNWPSTLTKHKRIHTGEKPYTC 344

Query: 247 SSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFT----TFQAWQLA 302
                           + F Q  NL       T +K  +C    + F+      +  ++ 
Sbjct: 345 EEC------------GKAFNQFSNLTTHKRIHTAEKFYKCTECGEAFSRSSNLTKHKKIH 392

Query: 303 TKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---P 359
           T+ K   C+E  ++ +  S       +E +L  T         ++  KC+   G+A   P
Sbjct: 393 TEKKPYKCEECGKAFKWSS-----KLTEHKLTHT--------GEKPYKCEEC-GKAFNWP 438

Query: 360 SVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGT 419
           S         + EKP  C  CGKAF  +  L  H R+H       AE P    +  +  +
Sbjct: 439 STLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTTHKRIHT------AEKPYKCEECGKAFS 492

Query: 420 CSPDLAAPLD---ENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHL-TSSRECSY 475
            S +L        E       E G        L E           KI H      +C  
Sbjct: 493 RSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTE----------HKITHTGEKPYKCEE 542

Query: 476 CGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           CGK F     L  H R HTGEKPYKCE C  A  Q ++L  H + H  EK
Sbjct: 543 CGKAFNHFSILTKHKRIHTGEKPYKCEECGKAFTQSSNLTTHKKIHTGEK 592



 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 95/390 (24%), Positives = 152/390 (38%), Gaps = 54/390 (13%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKH--VLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F     L KH  +    +P  CE  V        S L          
Sbjct: 422 GEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCE--VCGKAFNQFSNLTTH------- 472

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K  +  E  + CE CG+ F  + ++  H + H +   Y C  CG+ FK    L  H  TH
Sbjct: 473 KRIHTAEKPYKCEECGKAFSRSSNLTKHKKIHIEKKPYKCEECGKAFKWSSKLTEHKITH 532

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+   + +      +  + + +  ++H  E    PYK C  CG  F    +L  H+K+H
Sbjct: 533 TGEKPYKCEECGKAFNHFSILTKHKRIHTGEK---PYK-CEECGKAFTQSSNLTTHKKIH 588

Query: 239 TKKT---------AFGTSSAQTDSPQ---GGMPSSREDFLQLFN----LRPKSHPETGKK 282
           T +          AF  SS  T   +   GG P   E+  + FN    L       T +K
Sbjct: 589 TGEKFYKCEECGKAFTQSSNLTTHKKIHTGGKPYKCEECGKAFNQFSTLTKHKIIHTEEK 648

Query: 283 PVRCIPQLDPF----TTFQAWQLATKGKVAICQEVKESGQEGSTDNDDS---SSEK---- 331
           P +C      F    T  +   + T  K   C+E  ++ +  ST +      + EK    
Sbjct: 649 PYKCEECGKAFKWSSTLTKHKIIHTGEKPYKCEECGKAFKLSSTLSTHKIIHTGEKPYKC 708

Query: 332 -ELGETNKGSCAGLSQEK----------EKCKHSHGEAPSVDADPKLPSSKEKPTHCSEC 380
            + G+    S   +  +K          E+C  +   +  ++   ++  +KE+P  C EC
Sbjct: 709 EKCGKAFNRSSNLIEHKKIHTGEQPYKCEECGKAFNYSSHLNTHKRI-HTKEQPYKCKEC 767

Query: 381 GKAFRTYHQLVLHSRVHKKDRRAGAESPTM 410
           GKAF  Y  L  H+++H  ++    E  T+
Sbjct: 768 GKAFNQYSNLTTHNKIHTGEKLYKPEDVTV 797



 Score = 70.9 bits (172), Expect = 6e-12
 Identities = 100/428 (23%), Positives = 153/428 (35%), Gaps = 99/428 (23%)

Query: 128 FSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSK 187
           F  + C + F    +   H  +H +   + C  CG+ F     L  H   H   +  + +
Sbjct: 146 FLFDKCVKAFHKFSNSNRHKISHTEKKLFKCKECGKSFCMLPHLAQHKIIHTRVNFCKCE 205

Query: 188 LQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTS 247
                 + P+ I +  +++  E    PY  C  CG +F     L  H+K +T+   +   
Sbjct: 206 KCGKAFNCPSIITKHKRINTGEK---PYT-CEECGKVFNWSSRLTTHKKNYTRYKLYKC- 260

Query: 248 SAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKV 307
                          E+  + FN   KS   T  K +R                 T  K 
Sbjct: 261 ---------------EECGKAFN---KSSILTTHKIIR-----------------TGEKF 285

Query: 308 AICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDAD 364
             C+E  ++  +       SS+  E  + + G      ++  KC+   G+A   PS    
Sbjct: 286 YKCKECAKAFNQ-------SSNLTEHKKIHPG------EKPYKCEEC-GKAFNWPSTLTK 331

Query: 365 PKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDL 424
            K   + EKP  C ECGKAF  +  L  H R+H  ++                       
Sbjct: 332 HKRIHTGEKPYTCEECGKAFNQFSNLTTHKRIHTAEKFYKC------------------- 372

Query: 425 AAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNY 484
                     + GE  S   +         L K+    KI       +C  CGK F+ + 
Sbjct: 373 ---------TECGEAFSRSSN---------LTKHK---KIHTEKKPYKCEECGKAFKWSS 411

Query: 485 YLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK--QTDVAAEVKNDGKNQDT 542
            L  H  THTGEKPYKCE C  A    ++L  H   H  EK  + +V  +  N   N  T
Sbjct: 412 KLTEHKLTHTGEKPYKCEECGKAFNWPSTLTKHNRIHTGEKPYKCEVCGKAFNQFSNLTT 471

Query: 543 EDALLTAD 550
              + TA+
Sbjct: 472 HKRIHTAE 479



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 37/155 (23%), Positives = 63/155 (40%), Gaps = 11/155 (7%)

Query: 50  ATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSP 107
           +T  K+ I   G  P  C  C + F  S  L+ H ++    +P  CE             
Sbjct: 663 STLTKHKIIHTGEKPYKCEECGKAFKLSSTLSTHKIIHTGEKPYKCEKCG--------KA 714

Query: 108 LDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKE 167
            ++S    E  K+ +  E  + CE CG+ F  +  +  H R H     Y C  CG+ F +
Sbjct: 715 FNRSSNLIEH-KKIHTGEQPYKCEECGKAFNYSSHLNTHKRIHTKEQPYKCKECGKAFNQ 773

Query: 168 PWFLKNHMRTHNGKSGARSKLQQGLESSPATINEV 202
              L  H + H G+   + +    + ++P T + +
Sbjct: 774 YSNLTTHNKIHTGEKLYKPEDVTVILTTPQTFSNI 808


>gi|117956407 zinc finger protein 568 [Homo sapiens]
          Length = 644

 Score =  125 bits (315), Expect = 2e-28
 Identities = 122/487 (25%), Positives = 190/487 (39%), Gaps = 92/487 (18%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNC 123
           P  C  C Q F+H  DL +H               R+ A                     
Sbjct: 221 PFKCNQCGQDFSHKFDLIRHE--------------RIHAG-------------------- 246

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
            E  + C+ CG+ F    ++  H + H     Y CN CG+ F +   L  H R H G+  
Sbjct: 247 -EKPYECKECGKAFSRKENLITHQKIHTGEKPYKCNECGKAFIQMSNLIRHHRIHTGEKP 305

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTA 243
              K      S  + + E  ++H  E    PY+ C  CG  F  K++LIEH K+HT +  
Sbjct: 306 YACKDCWKAFSQKSNLIEHERIHTGE---KPYE-CKECGKSFSQKQNLIEHEKIHTGEKP 361

Query: 244 FGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAW---- 299
           +  +         G   SR   +    L  +SH  TG+KP +C      F+    +    
Sbjct: 362 YACNEC-------GRAFSR---MSSVTLHMRSH--TGEKPYKCNKCGKAFSQCSVFIIHM 409

Query: 300 QLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAP 359
           +  T  K  +C E  ++  + S+          L    +   A    E ++C  +     
Sbjct: 410 RSHTGEKPYVCSECGKAFSQSSS----------LTVHMRNHTAEKPYECKECGKAFSRKE 459

Query: 360 SVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDR--------RAGAESPTMS 411
           ++    K+ +  EKP  CSECGKAF     L+ H R+H  ++        +A ++   ++
Sbjct: 460 NLITHQKIHTG-EKPYECSECGKAFIQMSNLIRHQRIHTGEKPYACTVCGKAFSQKSNLT 518

Query: 412 V-----DGRQPGTCSP-----DLAAPLDENGAVDRGEGG---SEDGSEDGLPEGIHLDKN 458
                  G +P  C+           L E+  +  GE     +E G        + L   
Sbjct: 519 EHEKIHTGEKPYHCNQCGKAFSQRQNLLEHEKIHTGEKPFKCNECGKAFSRISSLTLHVR 578

Query: 459 DDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHL 518
              G+  +     EC+ CGK F     L IH+R+HTGEKP++C  C  A +Q+ SL  H 
Sbjct: 579 SHTGEKPY-----ECNKCGKAFSQCSLLIIHMRSHTGEKPFECNECGKAFSQRASLSIHK 633

Query: 519 ERHHKEK 525
             H  E+
Sbjct: 634 RGHTGER 640



 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 85/355 (23%), Positives = 140/355 (39%), Gaps = 62/355 (17%)

Query: 51  TQEKNVIQIE----GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLS 106
           +Q+ N+I+ E    G  P +C  C ++F+  ++L +H                       
Sbjct: 316 SQKSNLIEHERIHTGEKPYECKECGKSFSQKQNLIEH----------------------- 352

Query: 107 PLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFK 166
                       ++ +  E  ++C  CG+ F     V +HMR+H     Y CN CG+ F 
Sbjct: 353 ------------EKIHTGEKPYACNECGRAFSRMSSVTLHMRSHTGEKPYKCNKCGKAFS 400

Query: 167 EPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFP 226
           +      HMR+H G+            S  +++   ++ H AE    PY+ C  CG  F 
Sbjct: 401 QCSVFIIHMRSHTGEKPYVCSECGKAFSQSSSLTVHMRNHTAE---KPYE-CKECGKAFS 456

Query: 227 NKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRC 286
            KE+LI H+K+HT +  +  S               + F+Q+ NL       TG+KP  C
Sbjct: 457 RKENLITHQKIHTGEKPYECSEC------------GKAFIQMSNLIRHQRIHTGEKPYAC 504

Query: 287 IPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQ 346
                 F+  Q   L    K+   ++     Q G       S  + L E  K        
Sbjct: 505 TVCGKAFS--QKSNLTEHEKIHTGEKPYHCNQCGKA----FSQRQNLLEHEKIHTGEKPF 558

Query: 347 EKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDR 401
           +  +C  +     S+    +   + EKP  C++CGKAF     L++H R H  ++
Sbjct: 559 KCNECGKAFSRISSLTLHVR-SHTGEKPYECNKCGKAFSQCSLLIIHMRSHTGEK 612



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 58/204 (28%), Positives = 82/204 (40%), Gaps = 30/204 (14%)

Query: 372 EKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVD-------------GRQPG 418
           EKP  C+ECGKAF     L+ H R+H  ++    +    +               G +P 
Sbjct: 275 EKPYKCNECGKAFIQMSNLIRHHRIHTGEKPYACKDCWKAFSQKSNLIEHERIHTGEKPY 334

Query: 419 TC-----SPDLAAPLDENGAVDRGE---GGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSS 470
            C     S      L E+  +  GE     +E G        + L      G+  +    
Sbjct: 335 ECKECGKSFSQKQNLIEHEKIHTGEKPYACNECGRAFSRMSSVTLHMRSHTGEKPY---- 390

Query: 471 RECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVA 530
            +C+ CGK F       IH+R+HTGEKPY C  C  A +Q +SL  H+  H  EK     
Sbjct: 391 -KCNKCGKAFSQCSVFIIHMRSHTGEKPYVCSECGKAFSQSSSLTVHMRNHTAEK----P 445

Query: 531 AEVKNDGKNQDTEDALLTADSAQT 554
            E K  GK    ++ L+T     T
Sbjct: 446 YECKECGKAFSRKENLITHQKIHT 469



 Score = 58.2 bits (139), Expect = 4e-08
 Identities = 42/181 (23%), Positives = 69/181 (38%), Gaps = 43/181 (23%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+   +L +H  +    +P  C     +  ++  + L+  ++ T   
Sbjct: 498 GEKPYACTVCGKAFSQKSNLTEHEKIHTGEKPYHCNQCG-KAFSQRQNLLEHEKIHTG-- 554

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
                 E  F C  CG+ F     + +H+R+H     Y CN CG+ F +   L  HMR+H
Sbjct: 555 ------EKPFKCNECGKAFSRISSLTLHVRSHTGEKPYECNKCGKAFSQCSLLIIHMRSH 608

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+                                P++ C  CG  F  + SL  H++ H
Sbjct: 609 TGEK-------------------------------PFE-CNECGKAFSQRASLSIHKRGH 636

Query: 239 T 239
           T
Sbjct: 637 T 637



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 37/140 (26%), Positives = 60/140 (42%), Gaps = 21/140 (15%)

Query: 51  TQEKNVIQIE----GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEP---AVLRVE 101
           +Q+ N+ + E    G  P  C  C + F+  ++L +H  +    +P  C     A  R+ 
Sbjct: 512 SQKSNLTEHEKIHTGEKPYHCNQCGKAFSQRQNLLEHEKIHTGEKPFKCNECGKAFSRIS 571

Query: 102 AEYLSPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMC 161
           +  L       VR+      +  E  + C  CG+ F     + IHMR+H     + CN C
Sbjct: 572 SLTL------HVRS------HTGEKPYECNKCGKAFSQCSLLIIHMRSHTGEKPFECNEC 619

Query: 162 GRRFKEPWFLKNHMRTHNGK 181
           G+ F +   L  H R H G+
Sbjct: 620 GKAFSQRASLSIHKRGHTGE 639


>gi|239753557 PREDICTED: zinc finger protein 852 [Homo sapiens]
          Length = 530

 Score =  124 bits (311), Expect = 5e-28
 Identities = 93/409 (22%), Positives = 165/409 (40%), Gaps = 69/409 (16%)

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + C  CG+TFR    + +H+RTH     Y C+ CG+ ++    L  H R HNG+   
Sbjct: 184 EKPYECNECGKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHSSHLIQHQRLHNGEKPY 243

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           +        +  + + +  + H  E    PY+ C  CG  F   ++L+ H+ +HT K  +
Sbjct: 244 KCNECAKAFNQSSKLFDHQRTHTGE---KPYE-CKECGAAFSRSKNLVRHQFLHTGKKPY 299

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATK 304
             +                 F    NL       TG+KP +C          +  +  ++
Sbjct: 300 KCNEC------------GRAFCSNRNLIDHQRTHTGEKPYKC---------NECGKAFSR 338

Query: 305 GKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKH---SHGEAPSV 361
            K  I  +   +G++    ++   +  ++ +  +       ++  KC     + G +  +
Sbjct: 339 SKCLIRHQSLHTGEKPYKCSECGKAFNQISQLVEHERIHTGEKPFKCSECGKAFGLSKCL 398

Query: 362 DADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCS 421
               +L +S EKP  C+ECGK+F     L++H R+H                G +P  C 
Sbjct: 399 IRHQRLHTS-EKPYKCNECGKSFNQNSYLIIHQRIH---------------TGEKPYEC- 441

Query: 422 PDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFR 481
                              +E G        + + +    G+  +     +C+ CGK F 
Sbjct: 442 -------------------NECGKVFSYNSSLMVHQRTHTGEKPY-----KCNSCGKAFS 477

Query: 482 SNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVA 530
            +  L +H R HTGEKPY+C  C  A +Q+++  +H   H  EK + +A
Sbjct: 478 DSSQLTVHQRVHTGEKPYECIECGKAFSQRSTFNHHQRTHAGEKPSGLA 526



 Score =  113 bits (283), Expect = 8e-25
 Identities = 115/454 (25%), Positives = 169/454 (37%), Gaps = 124/454 (27%)

Query: 99  RVEAEYLSPLDKS-------------QVRTEPPKEKNCKENE--------FSCEVCGQTF 137
           R+E+++L  +D+              +V   PP   +  E+E        + C+ CG+ F
Sbjct: 109 RLESDFLEIIDEDKKKSTKDRYEEYKEVEEHPPLSSSPVEHEGVLKGQKSYRCDECGKAF 168

Query: 138 RVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG-KSGARSKLQQGLESSP 196
             +  +  H R H     Y CN CG+ F++   L  H+RTH G K    S+  +    S 
Sbjct: 169 YWSSHLIGHRRIHTGEKPYECNECGKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHS- 227

Query: 197 ATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQG 256
              + ++Q     +   PYK C  C   F     L +H++ HT +  +       +  + 
Sbjct: 228 ---SHLIQHQRLHNGEKPYK-CNECAKAFNQSSKLFDHQRTHTGEKPY-------ECKEC 276

Query: 257 GMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKES 316
           G   SR       NL       TGKKP +C          +  +     +  I  +   +
Sbjct: 277 GAAFSRSK-----NLVRHQFLHTGKKPYKC---------NECGRAFCSNRNLIDHQRTHT 322

Query: 317 GQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTH 376
           G++    N+                 G +  + KC   H              + EKP  
Sbjct: 323 GEKPYKCNE----------------CGKAFSRSKCLIRHQSL----------HTGEKPYK 356

Query: 377 CSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDR 436
           CSECGKAF    QLV H R+H                G +P  C                
Sbjct: 357 CSECGKAFNQISQLVEHERIH---------------TGEKPFKC---------------- 385

Query: 437 GEGGSEDGSEDGLPEGIHLDKNDDGGKIKHL---TSSR--ECSYCGKFFRSNYYLNIHLR 491
               SE G   GL + +          I+H    TS +  +C+ CGK F  N YL IH R
Sbjct: 386 ----SECGKAFGLSKCL----------IRHQRLHTSEKPYKCNECGKSFNQNSYLIIHQR 431

Query: 492 THTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
            HTGEKPY+C  C    +  +SL  H   H  EK
Sbjct: 432 IHTGEKPYECNECGKVFSYNSSLMVHQRTHTGEK 465



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 49/195 (25%), Positives = 79/195 (40%), Gaps = 19/195 (9%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F     L +H  +    +P  C       E      L K  +R +  
Sbjct: 351 GEKPYKCSECGKAFNQISQLVEHERIHTGEKPFKCS------ECGKAFGLSKCLIRHQ-- 402

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
              +  E  + C  CG++F     + IH R H     Y CN CG+ F     L  H RTH
Sbjct: 403 -RLHTSEKPYKCNECGKSFNQNSYLIIHQRIHTGEKPYECNECGKVFSYNSSLMVHQRTH 461

Query: 179 NGKSGARSKL--QQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRK 236
            G+   +     +   +SS  T+++  +VH  E    PY+ C+ CG  F  + +   H++
Sbjct: 462 TGEKPYKCNSCGKAFSDSSQLTVHQ--RVHTGEK---PYE-CIECGKAFSQRSTFNHHQR 515

Query: 237 VHTKKTAFGTSSAQT 251
            H  +   G + + +
Sbjct: 516 THAGEKPSGLARSSS 530



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 54/232 (23%), Positives = 84/232 (36%), Gaps = 61/232 (26%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+ S+ L +H  +    +P  C     +   +    ++  ++ T   
Sbjct: 323 GEKPYKCNECGKAFSRSKCLIRHQSLHTGEKPYKCSECG-KAFNQISQLVEHERIHTG-- 379

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
                 E  F C  CG+ F ++  +  H R H     Y CN CG+ F +  +L  H R H
Sbjct: 380 ------EKPFKCSECGKAFGLSKCLIRHQRLHTSEKPYKCNECGKSFNQNSYLIIHQRIH 433

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+                                PY+ C  CG +F    SL+ H++ H
Sbjct: 434 TGEK-------------------------------PYE-CNECGKVFSYNSSLMVHQRTH 461

Query: 239 TKKTAFGTSS---AQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCI 287
           T +  +  +S   A +DS Q               L       TG+KP  CI
Sbjct: 462 TGEKPYKCNSCGKAFSDSSQ---------------LTVHQRVHTGEKPYECI 498


>gi|239742001 PREDICTED: zinc finger protein 852 [Homo sapiens]
          Length = 530

 Score =  124 bits (311), Expect = 5e-28
 Identities = 93/409 (22%), Positives = 165/409 (40%), Gaps = 69/409 (16%)

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + C  CG+TFR    + +H+RTH     Y C+ CG+ ++    L  H R HNG+   
Sbjct: 184 EKPYECNECGKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHSSHLIQHQRLHNGEKPY 243

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           +        +  + + +  + H  E    PY+ C  CG  F   ++L+ H+ +HT K  +
Sbjct: 244 KCNECAKAFNQSSKLFDHQRTHTGE---KPYE-CKECGAAFSRSKNLVRHQFLHTGKKPY 299

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATK 304
             +                 F    NL       TG+KP +C          +  +  ++
Sbjct: 300 KCNEC------------GRAFCSNRNLIDHQRTHTGEKPYKC---------NECGKAFSR 338

Query: 305 GKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKH---SHGEAPSV 361
            K  I  +   +G++    ++   +  ++ +  +       ++  KC     + G +  +
Sbjct: 339 SKCLIRHQSLHTGEKPYKCSECGKAFNQISQLVEHERIHTGEKPFKCSECGKAFGLSKCL 398

Query: 362 DADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCS 421
               +L +S EKP  C+ECGK+F     L++H R+H                G +P  C 
Sbjct: 399 IRHQRLHTS-EKPYKCNECGKSFNQNSYLIIHQRIH---------------TGEKPYEC- 441

Query: 422 PDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFR 481
                              +E G        + + +    G+  +     +C+ CGK F 
Sbjct: 442 -------------------NECGKVFSYNSSLMVHQRTHTGEKPY-----KCNSCGKAFS 477

Query: 482 SNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVA 530
            +  L +H R HTGEKPY+C  C  A +Q+++  +H   H  EK + +A
Sbjct: 478 DSSQLTVHQRVHTGEKPYECIECGKAFSQRSTFNHHQRTHAGEKPSGLA 526



 Score =  113 bits (283), Expect = 8e-25
 Identities = 115/454 (25%), Positives = 169/454 (37%), Gaps = 124/454 (27%)

Query: 99  RVEAEYLSPLDKS-------------QVRTEPPKEKNCKENE--------FSCEVCGQTF 137
           R+E+++L  +D+              +V   PP   +  E+E        + C+ CG+ F
Sbjct: 109 RLESDFLEIIDEDKKKSTKDRYEEYKEVEEHPPLSSSPVEHEGVLKGQKSYRCDECGKAF 168

Query: 138 RVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG-KSGARSKLQQGLESSP 196
             +  +  H R H     Y CN CG+ F++   L  H+RTH G K    S+  +    S 
Sbjct: 169 YWSSHLIGHRRIHTGEKPYECNECGKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHS- 227

Query: 197 ATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQG 256
              + ++Q     +   PYK C  C   F     L +H++ HT +  +       +  + 
Sbjct: 228 ---SHLIQHQRLHNGEKPYK-CNECAKAFNQSSKLFDHQRTHTGEKPY-------ECKEC 276

Query: 257 GMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKES 316
           G   SR       NL       TGKKP +C          +  +     +  I  +   +
Sbjct: 277 GAAFSRSK-----NLVRHQFLHTGKKPYKC---------NECGRAFCSNRNLIDHQRTHT 322

Query: 317 GQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTH 376
           G++    N+                 G +  + KC   H              + EKP  
Sbjct: 323 GEKPYKCNE----------------CGKAFSRSKCLIRHQSL----------HTGEKPYK 356

Query: 377 CSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDR 436
           CSECGKAF    QLV H R+H                G +P  C                
Sbjct: 357 CSECGKAFNQISQLVEHERIH---------------TGEKPFKC---------------- 385

Query: 437 GEGGSEDGSEDGLPEGIHLDKNDDGGKIKHL---TSSR--ECSYCGKFFRSNYYLNIHLR 491
               SE G   GL + +          I+H    TS +  +C+ CGK F  N YL IH R
Sbjct: 386 ----SECGKAFGLSKCL----------IRHQRLHTSEKPYKCNECGKSFNQNSYLIIHQR 431

Query: 492 THTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
            HTGEKPY+C  C    +  +SL  H   H  EK
Sbjct: 432 IHTGEKPYECNECGKVFSYNSSLMVHQRTHTGEK 465



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 49/195 (25%), Positives = 79/195 (40%), Gaps = 19/195 (9%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F     L +H  +    +P  C       E      L K  +R +  
Sbjct: 351 GEKPYKCSECGKAFNQISQLVEHERIHTGEKPFKCS------ECGKAFGLSKCLIRHQ-- 402

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
              +  E  + C  CG++F     + IH R H     Y CN CG+ F     L  H RTH
Sbjct: 403 -RLHTSEKPYKCNECGKSFNQNSYLIIHQRIHTGEKPYECNECGKVFSYNSSLMVHQRTH 461

Query: 179 NGKSGARSKL--QQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRK 236
            G+   +     +   +SS  T+++  +VH  E    PY+ C+ CG  F  + +   H++
Sbjct: 462 TGEKPYKCNSCGKAFSDSSQLTVHQ--RVHTGEK---PYE-CIECGKAFSQRSTFNHHQR 515

Query: 237 VHTKKTAFGTSSAQT 251
            H  +   G + + +
Sbjct: 516 THAGEKPSGLARSSS 530



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 54/232 (23%), Positives = 84/232 (36%), Gaps = 61/232 (26%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+ S+ L +H  +    +P  C     +   +    ++  ++ T   
Sbjct: 323 GEKPYKCNECGKAFSRSKCLIRHQSLHTGEKPYKCSECG-KAFNQISQLVEHERIHTG-- 379

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
                 E  F C  CG+ F ++  +  H R H     Y CN CG+ F +  +L  H R H
Sbjct: 380 ------EKPFKCSECGKAFGLSKCLIRHQRLHTSEKPYKCNECGKSFNQNSYLIIHQRIH 433

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+                                PY+ C  CG +F    SL+ H++ H
Sbjct: 434 TGEK-------------------------------PYE-CNECGKVFSYNSSLMVHQRTH 461

Query: 239 TKKTAFGTSS---AQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCI 287
           T +  +  +S   A +DS Q               L       TG+KP  CI
Sbjct: 462 TGEKPYKCNSCGKAFSDSSQ---------------LTVHQRVHTGEKPYECI 498


>gi|47716687 zinc finger protein 167 isoform 1 [Homo sapiens]
          Length = 754

 Score =  123 bits (309), Expect = 8e-28
 Identities = 103/416 (24%), Positives = 159/416 (38%), Gaps = 77/416 (18%)

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + C  CG+TFR    + +H+RTH     Y C+ CG+ ++    L  H R HNG+   
Sbjct: 408 EKPYECNECGKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHSSHLIQHQRLHNGEKPY 467

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           +        +  + + +  + H  E    PY+ C  CG  F   +SL  H+ +HT K  +
Sbjct: 468 KCNECAKAFTQSSRLTDHQRTHTGE---KPYE-CNECGEAFIRSKSLARHQVLHTGKKPY 523

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFT----TFQAWQ 300
             +                 F    NL       TG+KP  C      F+      +   
Sbjct: 524 KCNEC------------GRAFCSNRNLIDHQRIHTGEKPYECSECGKAFSRSKCLIRHQS 571

Query: 301 LATKGKVAICQEVKESGQEGSTDNDDS---SSEKELGETNKGSCAGLSQEKEKCKHSHGE 357
           L T  K   C E  ++  + S   +     + EK    +  G   GLS    KC   H  
Sbjct: 572 LHTGEKPYKCSECGKAFNQNSQLIEHERIHTGEKPFECSECGKAFGLS----KCLIRHQR 627

Query: 358 APSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQP 417
                       + EKP  C+ECGK+F     L++H R+H                G +P
Sbjct: 628 L----------HTGEKPYKCNECGKSFNQNSHLIIHQRIH---------------TGEKP 662

Query: 418 GTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCG 477
             C                    +E G        + + +    G+  +     +C+ CG
Sbjct: 663 YEC--------------------NECGKVFSYSSSLMVHQRTHTGEKPY-----KCNDCG 697

Query: 478 KFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTDVAAEV 533
           K F  +  L +H R HTGEKPY+C  C  A +Q+++  +H   H  EK + +A  V
Sbjct: 698 KAFSDSSQLIVHQRVHTGEKPYECSECGKAFSQRSTFNHHQRTHTGEKSSGLAWSV 753



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 80/345 (23%), Positives = 116/345 (33%), Gaps = 60/345 (17%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
           G  P  C  C++ FT S  L  H                                   + 
Sbjct: 463 GEKPYKCNECAKAFTQSSRLTDH-----------------------------------QR 487

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
            +  E  + C  CG+ F  +  +  H   H     Y CN CGR F     L +H R H G
Sbjct: 488 THTGEKPYECNECGEAFIRSKSLARHQVLHTGKKPYKCNECGRAFCSNRNLIDHQRIHTG 547

Query: 181 -KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHT 239
            K    S+  +    S   I     +H  E    PYK C  CG  F     LIEH ++HT
Sbjct: 548 EKPYECSECGKAFSRSKCLIRH-QSLHTGE---KPYK-CSECGKAFNQNSQLIEHERIHT 602

Query: 240 KKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAW 299
            +  F  S         G+            L       TG+KP +C      F   Q  
Sbjct: 603 GEKPFECSEC---GKAFGLSKC---------LIRHQRLHTGEKPYKCNECGKSFN--QNS 648

Query: 300 QLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAP 359
            L    ++   ++  E  + G   +  SS    L    +        +   C  +  ++ 
Sbjct: 649 HLIIHQRIHTGEKPYECNECGKVFSYSSS----LMVHQRTHTGEKPYKCNDCGKAFSDSS 704

Query: 360 SVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAG 404
            +    ++ +  EKP  CSECGKAF        H R H  ++ +G
Sbjct: 705 QLIVHQRVHTG-EKPYECSECGKAFSQRSTFNHHQRTHTGEKSSG 748



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 60/226 (26%), Positives = 84/226 (37%), Gaps = 55/226 (24%)

Query: 309 ICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLP 368
           +C++  +  +  ++D + S  E +  E           +K+  K  + +   V   P L 
Sbjct: 314 VCEDTFKELEGQTSDEEGSRLENDFLEITD------EDKKKSTKDRYDKYKEVGEHPPLS 367

Query: 369 SSK---------EKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGT 419
           SS          +K   C ECGKAF     L+ H R+H                G +P  
Sbjct: 368 SSPVEHEGVLKGQKSYRCDECGKAFNRSSHLIGHQRIH---------------TGEKPYE 412

Query: 420 CSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKF 479
           C+                E G        L   +HL +   G K        ECS CGK 
Sbjct: 413 CN----------------ECGKTFRQTSQLI--VHL-RTHTGEK------PYECSECGKA 447

Query: 480 FRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           +R + +L  H R H GEKPYKC  C  A  Q + L  H   H  EK
Sbjct: 448 YRHSSHLIQHQRLHNGEKPYKCNECAKAFTQSSRLTDHQRTHTGEK 493


>gi|34419633 zinc finger protein 135 [Homo sapiens]
          Length = 658

 Score =  121 bits (304), Expect = 3e-27
 Identities = 118/473 (24%), Positives = 181/473 (38%), Gaps = 64/473 (13%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEK 121
           P  C  C + F+HS  L +H       RP  C         E L     S   T+  +  
Sbjct: 213 PYKCQECGKAFSHSSALIEHHRTHTGERPYECH--------ECLKGFRNSSALTKHQRI- 263

Query: 122 NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
           +  E  + C  CG+TF     +  H RTH     Y C+ CG+ F        H RTH G+
Sbjct: 264 HTGEKPYKCTQCGRTFNQIAPLIQHQRTHTGEKPYECSECGKSFSFRSSFSQHERTHTGE 323

Query: 182 SGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKK 241
                            + + +++H  E    PY+ C  CG  F +  SL +H+++HT +
Sbjct: 324 KPYECSECGKAFRQSIHLTQHLRIHTGEK---PYQ-CGECGKAFSHSSSLTKHQRIHTGE 379

Query: 242 TAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQL 301
             +                  + F Q+  L       TG+KP  C      F+  Q+  L
Sbjct: 380 KPYECHECG------------KAFTQITPLIQHQRTHTGEKPYECGECGKAFS--QSTLL 425

Query: 302 ATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSV 361
               ++   ++     + G T +  SS    L +  +        E  +C  +  ++  +
Sbjct: 426 TEHRRIHTGEKPYGCNECGKTFSHSSS----LSQHERTHTGEKPYECSQCGKAFRQSTHL 481

Query: 362 DADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCS 421
               ++ +  EKP  C++CGKAF     L  H R+H  ++           +  Q G   
Sbjct: 482 TQHQRIHTG-EKPYECNDCGKAFSHSSSLTKHQRIHTGEK---------PYECNQCGRAF 531

Query: 422 PDLAAPLDENGAVDRGEGGSEDG------SEDGL---PEGIHLDKNDDGGKIKHLTSSRE 472
             LA PL ++  +  GE   E        S+  L    + IH  +   G           
Sbjct: 532 SQLA-PLIQHQRIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYG----------- 579

Query: 473 CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           C+ CGK F  +  L+ H RTHTGEKPY+C  C  +  Q T L  H   H  EK
Sbjct: 580 CNECGKSFSHSSSLSQHERTHTGEKPYECHDCGKSFRQSTHLTQHRRIHTGEK 632



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 103/393 (26%), Positives = 146/393 (37%), Gaps = 81/393 (20%)

Query: 142 DVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGAR-SKLQQGLESSPATIN 200
           D+ +  +T      Y C  CG+ F     L  H RTH G+      +  +G  +S A + 
Sbjct: 200 DLNVLQKTCVKEKPYKCQECGKAFSHSSALIEHHRTHTGERPYECHECLKGFRNSSA-LT 258

Query: 201 EVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPS 260
           +  ++H  E    PYK C  CG  F     LI+H++ HT +  +  S        G   S
Sbjct: 259 KHQRIHTGE---KPYK-CTQCGRTFNQIAPLIQHQRTHTGEKPYECSEC------GKSFS 308

Query: 261 SREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEG 320
            R  F Q      ++H  TG+KP  C               A +  + + Q ++    E 
Sbjct: 309 FRSSFSQ----HERTH--TGEKPYEC----------SECGKAFRQSIHLTQHLRIHTGE- 351

Query: 321 STDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSEC 380
                      + GE  K      S  K +  H                + EKP  C EC
Sbjct: 352 --------KPYQCGECGKAFSHSSSLTKHQRIH----------------TGEKPYECHEC 387

Query: 381 GKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSP-----DLAAPLDENGAVD 435
           GKAF     L+ H R H                G +P  C         +  L E+  + 
Sbjct: 388 GKAFTQITPLIQHQRTH---------------TGEKPYECGECGKAFSQSTLLTEHRRIH 432

Query: 436 RGE---GGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRT 492
            GE   G +E G        +   +    G+  +     ECS CGK FR + +L  H R 
Sbjct: 433 TGEKPYGCNECGKTFSHSSSLSQHERTHTGEKPY-----ECSQCGKAFRQSTHLTQHQRI 487

Query: 493 HTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           HTGEKPY+C  C  A +  +SL  H   H  EK
Sbjct: 488 HTGEKPYECNDCGKAFSHSSSLTKHQRIHTGEK 520



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 85/341 (24%), Positives = 126/341 (36%), Gaps = 38/341 (11%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
           G  P  C  C + F+HS  L KH  +       E          ++PL + Q        
Sbjct: 350 GEKPYQCGECGKAFSHSSSLTKHQRIHTGEKPYECHECGKAFTQITPLIQHQ-------R 402

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
            +  E  + C  CG+ F  +  +  H R H     YGCN CG+ F     L  H RTH G
Sbjct: 403 THTGEKPYECGECGKAFSQSTLLTEHRRIHTGEKPYGCNECGKTFSHSSSLSQHERTHTG 462

Query: 181 KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
           +                 + +  ++H  E    PY+ C  CG  F +  SL +H+++HT 
Sbjct: 463 EKPYECSQCGKAFRQSTHLTQHQRIHTGEK---PYE-CNDCGKAFSHSSSLTKHQRIHTG 518

Query: 241 KTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTT----F 296
           +  +  +                 F QL  L       TG+KP  C      F+      
Sbjct: 519 EKPYECNQCG------------RAFSQLAPLIQHQRIHTGEKPYECNQCGRAFSQSSLLI 566

Query: 297 QAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHG 356
           +  ++ TK K   C E  +S    S     S S+ E   T +        E   C  S  
Sbjct: 567 EHQRIHTKEKPYGCNECGKSFSHSS-----SLSQHERTHTGEKP-----YECHDCGKSFR 616

Query: 357 EAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
           ++  +    ++ +  EKP  C +CGKAF     L  H R H
Sbjct: 617 QSTHLTQHRRIHTG-EKPYACRDCGKAFTHSSSLTKHQRTH 656



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 50/181 (27%), Positives = 72/181 (39%), Gaps = 15/181 (8%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C + F+HS  L KH  +    +P  C           L+PL + Q      
Sbjct: 490 GEKPYECNDCGKAFSHSSSLTKHQRIHTGEKPYECNQCGRAFSQ--LAPLIQHQ------ 541

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
              +  E  + C  CG+ F  +  +  H R H     YGCN CG+ F     L  H RTH
Sbjct: 542 -RIHTGEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTH 600

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+                 + +  ++H  E    PY  C  CG  F +  SL +H++ H
Sbjct: 601 TGEKPYECHDCGKSFRQSTHLTQHRRIHTGEK---PYA-CRDCGKAFTHSSSLTKHQRTH 656

Query: 239 T 239
           T
Sbjct: 657 T 657



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 33/123 (26%), Positives = 51/123 (41%), Gaps = 13/123 (10%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKH--VLMQHRPTLC-EPAVLRVEAEYLSPLDKSQVRTEP 117
           G  P +C  C + F+ S  L +H  +  + +P  C E       +  LS  +++    +P
Sbjct: 546 GEKPYECNQCGRAFSQSSLLIEHQRIHTKEKPYGCNECGKSFSHSSSLSQHERTHTGEKP 605

Query: 118 PKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRT 177
                     + C  CG++FR +  +  H R H     Y C  CG+ F     L  H RT
Sbjct: 606 ----------YECHDCGKSFRQSTHLTQHRRIHTGEKPYACRDCGKAFTHSSSLTKHQRT 655

Query: 178 HNG 180
           H G
Sbjct: 656 HTG 658


>gi|32698886 zinc finger protein 595 [Homo sapiens]
          Length = 648

 Score =  121 bits (303), Expect = 4e-27
 Identities = 121/489 (24%), Positives = 185/489 (37%), Gaps = 75/489 (15%)

Query: 67  CMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCK 124
           C  C + F+   + NKH +     +P  C        + Y+S L +           +  
Sbjct: 147 CNTCVKVFSKFSNSNKHKIRHTGEKPFKCTECG---RSFYMSHLTQHT-------GIHAG 196

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + CE CG+ F  +  +  H R H     Y C  CG+ F+    L  H + H G+   
Sbjct: 197 EKPYKCEKCGKAFNRSTSLSKHKRIHTGEKPYTCEECGKAFRRSTVLNEHKKIHTGEKPY 256

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           + +      +   T+NE  ++H  E    PYK C  CG  F    SL EH+ +HT +  +
Sbjct: 257 KCEECGKAFTRSTTLNEHKKIHTGEK---PYK-CKECGKAFRWSTSLNEHKNIHTGEKPY 312

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAW----Q 300
                             + F Q  +L    +  TG+KP  C      F    +      
Sbjct: 313 KCKECG------------KAFRQSRSLNEHKNIHTGEKPYTCEKCGKAFNQSSSLIIHRS 360

Query: 301 LATKGKVAICQEVKESGQEGSTDNDDS---SSEKELGETNKGSCAGLSQEKEKCKHSHGE 357
           + ++ K+  C+E  ++    S+ N      + EK       G     S    K K  H  
Sbjct: 361 IHSEQKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIH-- 418

Query: 358 APSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDR--------RAGAESPT 409
                       + EKP  C ECGKAF     L+LH R+H   +        +A   S T
Sbjct: 419 ------------TGEKPYTCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTT 466

Query: 410 MSVD-----GRQPGTCSPD-----LAAPLDENGAVDRGEGG---SEDGSEDGLPEGIHLD 456
           ++       G +P  C         +A L+E+  +  GE      E G       G+ + 
Sbjct: 467 LNEHKKIHTGEKPYKCEECGKAFIWSASLNEHKNIHTGEKPYKCKECGKAFNQSSGLIIH 526

Query: 457 KNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRY 516
           ++     I       +C  CGK F  +  LN H + H+GEKPYKC+ C  A    ++L  
Sbjct: 527 RS-----IHSEQKLYKCEECGKAFTRSTALNEHKKIHSGEKPYKCKECGKAYNLSSTLTK 581

Query: 517 HLERHHKEK 525
           H   H  EK
Sbjct: 582 HKRIHTGEK 590



 Score =  114 bits (286), Expect = 4e-25
 Identities = 123/486 (25%), Positives = 184/486 (37%), Gaps = 64/486 (13%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F  S  L+KH  +    +P  CE        E      +S V  E  
Sbjct: 196 GEKPYKCEKCGKAFNRSTSLSKHKRIHTGEKPYTCE--------ECGKAFRRSTVLNEH- 246

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K+ +  E  + CE CG+ F  +  +  H + H     Y C  CG+ F+    L  H   H
Sbjct: 247 KKIHTGEKPYKCEECGKAFTRSTTLNEHKKIHTGEKPYKCKECGKAFRWSTSLNEHKNIH 306

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+   + K          ++NE   +H  E    PY  C  CG  F    SLI HR +H
Sbjct: 307 TGEKPYKCKECGKAFRQSRSLNEHKNIHTGEK---PYT-CEKCGKAFNQSSSLIIHRSIH 362

Query: 239 TKKT---------AFGTSSAQTDSPQ---GGMPSSRED----FLQLFNLRPKSHPETGKK 282
           +++          AF  SS+     +   G  P + E+    F +  +L       TG+K
Sbjct: 363 SEQKLYKCEECGKAFTWSSSLNKHKRIHTGEKPYTCEECGKAFYRSSHLAKHKRIHTGEK 422

Query: 283 PVRCIPQLDPF----TTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNK 338
           P  C      F    T     ++ +  K   C+E  ++    +T          L E  K
Sbjct: 423 PYTCEECGKAFNQSSTLILHKRIHSGQKPYKCEECGKAFTRSTT----------LNEHKK 472

Query: 339 GSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHK 398
                   + E+C  +   + S++    + +  EKP  C ECGKAF     L++H  +H 
Sbjct: 473 IHTGEKPYKCEECGKAFIWSASLNEHKNIHTG-EKPYKCKECGKAFNQSSGLIIHRSIHS 531

Query: 399 KDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGG---SEDGSEDGLPEGIHL 455
           + +    E    +             +  L+E+  +  GE      E G    L   +  
Sbjct: 532 EQKLYKCEECGKAFTR----------STALNEHKKIHSGEKPYKCKECGKAYNLSSTLTK 581

Query: 456 DKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLR 515
            K    G+ K  T    C  CGK F  +  L  H   HTGEK YKCE C  A  + ++L 
Sbjct: 582 HKRIHTGE-KPFT----CEECGKAFNWSSSLTKHKIIHTGEKSYKCEECGKAFNRPSTLT 636

Query: 516 YHLERH 521
            H   H
Sbjct: 637 VHKRIH 642



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 41/181 (22%), Positives = 62/181 (34%), Gaps = 39/181 (21%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
           G  P  C  C + F  S  L     + HR    E  + + E E      +S    E  K+
Sbjct: 504 GEKPYKCKECGKAFNQSSGL-----IIHRSIHSEQKLYKCE-ECGKAFTRSTALNEH-KK 556

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
            +  E  + C+ CG+ + ++  +  H R H     + C  CG+ F     L  H   H G
Sbjct: 557 IHSGEKPYKCKECGKAYNLSSTLTKHKRIHTGEKPFTCEECGKAFNWSSSLTKHKIIHTG 616

Query: 181 KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
           +                                 YK C  CG  F    +L  H+++HT 
Sbjct: 617 EKS-------------------------------YK-CEECGKAFNRPSTLTVHKRIHTG 644

Query: 241 K 241
           K
Sbjct: 645 K 645


>gi|239757212 PREDICTED: similar to hCG1773661 [Homo sapiens]
          Length = 1119

 Score =  119 bits (297), Expect = 2e-26
 Identities = 131/506 (25%), Positives = 198/506 (39%), Gaps = 66/506 (13%)

Query: 64   PLDCMFCSQTFTHSEDLNKHVLMQHRPTL--CEPAVLRVEAEYLSPLDKSQVRTEPPKEK 121
            P  C  C ++F H   L KH ++  R  L  CE  V    +   S L K +V        
Sbjct: 606  PCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS--FSALMKHKVI------- 656

Query: 122  NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
            +  E  + CE CG+ F+ +  + +H   H       C  CG+ FK    L+ H   H GK
Sbjct: 657  HTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGK 716

Query: 182  SGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKK 241
               + +      S  +++ +   +H+ E    PYK C  CG  F     L  H+ +HT +
Sbjct: 717  KPYKCEECGKAFSQSSSLRKHEIIHSGEK---PYK-CEECGKAFKWLSKLTVHKVIHTAE 772

Query: 242  T---------AFGTSSAQTDSP---QGGMPSSREDFLQLFN----LRPKSHPETGKKPVR 285
                      AF   SA         G  P   E+  + FN    L       TGKKP +
Sbjct: 773  KPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYK 832

Query: 286  CIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLS 345
            C    +    F+     T+ K     E     +E   D ++SS+ K      K       
Sbjct: 833  CA---ECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLK------KHKLIHTR 883

Query: 346  QEKEKCKHSHGEAPSVDA--DPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRA 403
            ++  KC+       +  A    K+  + EKP  C ECGKAF+   +L  H  +H  ++  
Sbjct: 884  EKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPC 943

Query: 404  GAESPTMSV-------------DGRQPGTCSP-----DLAAPLDENGAVDRGEGGSE-DG 444
              E    +               G++P  C       + ++ L ++  +  GE   + + 
Sbjct: 944  KCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEE 1003

Query: 445  SEDGLPEGIHLDKNDDGGKIKH-LTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEF 503
                  +   L K+    KI H +    +C  CGK F  + +L  H   HTGEKPYKCE 
Sbjct: 1004 CGKAFSQSSILTKH----KIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEE 1059

Query: 504  CEYAAAQKTSLRYHLERHHKEKQTDV 529
            C  A  Q + L  H   H +EK T+V
Sbjct: 1060 CGKAFIQCSYLIRHKTIHTREKPTNV 1085



 Score =  112 bits (280), Expect = 2e-24
 Identities = 123/505 (24%), Positives = 183/505 (36%), Gaps = 100/505 (19%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNC 123
           P  C  C +TF H   L KH ++       +           S L K ++        + 
Sbjct: 186 PYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEII-------HT 238

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
            E  + CE CG+ F+ +  + +H   H     Y C  CG+ F +   LK H   H GK  
Sbjct: 239 GEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKP 298

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTA 243
            + +      +S +T+ +   +H  E    PYK C  CG  F     L  H+ +HT    
Sbjct: 299 YKCEECGKAFNSSSTLMKHKIIHTGE---KPYK-CEECGKAFRQSSHLTRHKAIHT---- 350

Query: 244 FGTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDPF---TTF 296
                       G  P   E+  + FN    LR      TGKKP +C      F   +T 
Sbjct: 351 ------------GEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSSTL 398

Query: 297 QAWQLATKG-KVAICQE---------------VKESGQEGSTDNDDSSSEKELGETNKGS 340
           +  Q+   G K   C+E               V  +G++     +   + K      K  
Sbjct: 399 RNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHK 458

Query: 341 CAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
                ++  KC+   G+A    S+ A  K+  + +KP  C ECGKAFR    L  H  +H
Sbjct: 459 VIHTREKLYKCEEC-GKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIH 517

Query: 398 KKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDK 457
                           G +P  C  +         A+ R              + IH  K
Sbjct: 518 ---------------TGEKPYKCE-ECGKAFSHFSALRR-------------HKIIHTGK 548

Query: 458 -----NDDGGKIKHLTSSR------------ECSYCGKFFRSNYYLNIHLRTHTGEKPYK 500
                 + G    H ++ R            +C  CGK F+ +  L +H   HT EKP K
Sbjct: 549 KPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCK 608

Query: 501 CEFCEYAAAQKTSLRYHLERHHKEK 525
           CE C  +    ++LR H   H +EK
Sbjct: 609 CEECGKSFKHFSALRKHKVIHTREK 633



 Score = 98.2 bits (243), Expect = 4e-20
 Identities = 115/480 (23%), Positives = 177/480 (36%), Gaps = 72/480 (15%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+H   L +H ++    +P  CE         + S L + ++     
Sbjct: 519 GEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFS--HFSALRRHKII---- 572

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
              +  E  + CE CG+ F+ +  + +H   H       C  CG+ FK    L+ H   H
Sbjct: 573 ---HTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIH 629

Query: 179 NGKSGARSKLQQGLESSPA--TINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRK 236
                 R KL +  E   A  + + +++     +   PYK C  CG  F     L  H+ 
Sbjct: 630 T-----REKLYKCEECVKAFNSFSALMKHKVIHTGEKPYK-CEECGKAFKWSSKLTVHKV 683

Query: 237 VHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDP 292
           +HT                G  P   E+  + F     LR      TGKKP +C      
Sbjct: 684 IHT----------------GEKPCKCEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKA 727

Query: 293 FTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCK 352
           F+   + +           E+  SG++     +   + K L +         +++  KC+
Sbjct: 728 FSQSSSLRK---------HEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCE 778

Query: 353 HSHGEAPSVDA--DPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTM 410
                     A    K+  + +KP  C ECGKAF     L+ H  +H             
Sbjct: 779 ECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHT------------ 826

Query: 411 SVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKH-LTS 469
              G++P  C+ +      ++  + R +     G +    E    D N+     KH L  
Sbjct: 827 ---GKKPYKCA-ECGKAFKQSSHLTRHKA-IHTGEKPYKCEECGKDFNNSSTLKKHKLIH 881

Query: 470 SRE----CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           +RE    C  C K F +   L  H   HTGEKPYKCE C  A    + L  H   H  EK
Sbjct: 882 TREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEK 941



 Score = 97.8 bits (242), Expect = 5e-20
 Identities = 125/550 (22%), Positives = 196/550 (35%), Gaps = 130/550 (23%)

Query: 48  FRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSP 107
           F     +N ++        C+ CS++F     L +H  +  R  + +        +  S 
Sbjct: 30  FHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFST 89

Query: 108 LDKSQV---RTEPPKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIH 146
           L K ++     +P K K C                   E  F CE CG+ F  + ++  H
Sbjct: 90  LTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDH 149

Query: 147 MRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVH 206
            R H    TY C  CG+ FK                              +  N    +H
Sbjct: 150 KRIHTGEKTYKCEECGKAFK----------------------------GSSNFNAHKVIH 181

Query: 207 AAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSRED-- 264
            AE    PYK C  CG  F +  +L +H+ +HT                G  P  RE+  
Sbjct: 182 TAE---KPYK-CEDCGKTFNHFSALRKHKIIHT----------------GKKPYKREECG 221

Query: 265 --FLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGST 322
             F Q   LR      TG+KP +C          +A++ ++K  V    +V  +G++   
Sbjct: 222 KAFSQSSTLRKHEIIHTGEKPYKC------EECGKAFKWSSKLTV---HKVVHTGEKPYK 272

Query: 323 DNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTHCSE 379
             +   +  +     K       ++  KC+   G+A    S     K+  + EKP  C E
Sbjct: 273 CEECGKAFSQFSTLKKHKIIHTGKKPYKCEEC-GKAFNSSSTLMKHKIIHTGEKPYKCEE 331

Query: 380 CGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVD-------------GRQPGTCSP---- 422
           CGKAFR    L  H  +H  ++    E    + +             G++P  C      
Sbjct: 332 CGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKA 391

Query: 423 -DLAAPLDENGAVDRGE---------GGSEDGSEDGLPEGIHLDK-----NDDGGKIKHL 467
              ++ L  +  +  GE            +  S+  + + IH  +      + G   KH 
Sbjct: 392 FSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHF 451

Query: 468 TSSR------------ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLR 515
           ++ R            +C  CGK F ++  L  H   HTG+KPYKCE C  A  Q + L 
Sbjct: 452 SALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLT 511

Query: 516 YHLERHHKEK 525
            H   H  EK
Sbjct: 512 RHKAIHTGEK 521



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 125/492 (25%), Positives = 175/492 (35%), Gaps = 96/492 (19%)

Query: 42   GTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLR 99
            G A   F A ++  VI   G  P  C  C + F+ S  L KH ++    +P  CE     
Sbjct: 697  GKAFKHFSALRKHKVIHT-GKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKA 755

Query: 100  VEAEYLSPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
             +  +LS L   +V      EK CK     CE CG+ F+    +  H   H     Y C 
Sbjct: 756  FK--WLSKLTVHKVIHTA--EKPCK-----CEECGKAFKHFSALRKHKIIHTGKKPYKCE 806

Query: 160  MCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICM 219
             CG+ F +   L  H   H GK   +           + +     +H  E    PYK C 
Sbjct: 807  ECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEK---PYK-CE 862

Query: 220  VCGFLFPNKESLIEHRKVHTKKT---------AFGTSSAQTDSP---QGGMPSSREDFLQ 267
             CG  F N  +L +H+ +HT++          AF   SA         G  P   E+  +
Sbjct: 863  ECGKDFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGK 922

Query: 268  LFNLRPK--SHP--ETGKKPVRCIPQLDPFTTFQAWQ----LATKGKVAICQEVKESGQE 319
             F    K   H    TG+KP +C      F  F A +    + T  K   C E  ++   
Sbjct: 923  AFKWSSKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNN 982

Query: 320  GSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTH 376
             ST               K       ++  KC+   G+A    S+    K+  S EKP  
Sbjct: 983  SST-------------LTKHKIIHTGEKPYKCEEC-GKAFSQSSILTKHKIIHSVEKPYK 1028

Query: 377  CSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDR 436
            C ECGKAF     L  H  +H                G +P  C     A +  +  +  
Sbjct: 1029 CEECGKAFNQSSHLTRHKTIH---------------TGEKPYKCEECGKAFIQCSYLIRH 1073

Query: 437  GEGGSEDGSEDGLPEGIHL-DKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTG 495
                          + IH  +K  +  K+  L              SN +  +    HTG
Sbjct: 1074 --------------KTIHTREKPTNVKKVPKLL-------------SNPHTLLDKTIHTG 1106

Query: 496  EKPYKCEFCEYA 507
            EKPYKCE C  A
Sbjct: 1107 EKPYKCEECAKA 1118



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 49/180 (27%), Positives = 72/180 (40%), Gaps = 17/180 (9%)

Query: 48   FRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYL 105
            F A ++  VI   G  P  C  C + F +S  L KH ++    +P  CE        E  
Sbjct: 955  FSALRKHKVIHT-GKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCE--------ECG 1005

Query: 106  SPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRF 165
                +S + T+  K  +  E  + CE CG+ F  +  +  H   H     Y C  CG+ F
Sbjct: 1006 KAFSQSSILTKH-KIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAF 1064

Query: 166  KEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLF 225
             +  +L  H   H  +     K    L S+P T+ +   +H  E    PYK C  C   F
Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKT-IHTGE---KPYK-CEECAKAF 1119


>gi|239751718 PREDICTED: similar to hCG1773661 [Homo sapiens]
          Length = 1119

 Score =  119 bits (297), Expect = 2e-26
 Identities = 131/506 (25%), Positives = 198/506 (39%), Gaps = 66/506 (13%)

Query: 64   PLDCMFCSQTFTHSEDLNKHVLMQHRPTL--CEPAVLRVEAEYLSPLDKSQVRTEPPKEK 121
            P  C  C ++F H   L KH ++  R  L  CE  V    +   S L K +V        
Sbjct: 606  PCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS--FSALMKHKVI------- 656

Query: 122  NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
            +  E  + CE CG+ F+ +  + +H   H       C  CG+ FK    L+ H   H GK
Sbjct: 657  HTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGK 716

Query: 182  SGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKK 241
               + +      S  +++ +   +H+ E    PYK C  CG  F     L  H+ +HT +
Sbjct: 717  KPYKCEECGKAFSQSSSLRKHEIIHSGEK---PYK-CEECGKAFKWLSKLTVHKVIHTAE 772

Query: 242  T---------AFGTSSAQTDSP---QGGMPSSREDFLQLFN----LRPKSHPETGKKPVR 285
                      AF   SA         G  P   E+  + FN    L       TGKKP +
Sbjct: 773  KPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYK 832

Query: 286  CIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLS 345
            C    +    F+     T+ K     E     +E   D ++SS+ K      K       
Sbjct: 833  CA---ECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLK------KHKLIHTR 883

Query: 346  QEKEKCKHSHGEAPSVDA--DPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRA 403
            ++  KC+       +  A    K+  + EKP  C ECGKAF+   +L  H  +H  ++  
Sbjct: 884  EKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPC 943

Query: 404  GAESPTMSV-------------DGRQPGTCSP-----DLAAPLDENGAVDRGEGGSE-DG 444
              E    +               G++P  C       + ++ L ++  +  GE   + + 
Sbjct: 944  KCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEE 1003

Query: 445  SEDGLPEGIHLDKNDDGGKIKH-LTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEF 503
                  +   L K+    KI H +    +C  CGK F  + +L  H   HTGEKPYKCE 
Sbjct: 1004 CGKAFSQSSILTKH----KIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEE 1059

Query: 504  CEYAAAQKTSLRYHLERHHKEKQTDV 529
            C  A  Q + L  H   H +EK T+V
Sbjct: 1060 CGKAFIQCSYLIRHKTIHTREKPTNV 1085



 Score =  112 bits (280), Expect = 2e-24
 Identities = 123/505 (24%), Positives = 183/505 (36%), Gaps = 100/505 (19%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNC 123
           P  C  C +TF H   L KH ++       +           S L K ++        + 
Sbjct: 186 PYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEII-------HT 238

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
            E  + CE CG+ F+ +  + +H   H     Y C  CG+ F +   LK H   H GK  
Sbjct: 239 GEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKP 298

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTA 243
            + +      +S +T+ +   +H  E    PYK C  CG  F     L  H+ +HT    
Sbjct: 299 YKCEECGKAFNSSSTLMKHKIIHTGE---KPYK-CEECGKAFRQSSHLTRHKAIHT---- 350

Query: 244 FGTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDPF---TTF 296
                       G  P   E+  + FN    LR      TGKKP +C      F   +T 
Sbjct: 351 ------------GEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSSTL 398

Query: 297 QAWQLATKG-KVAICQE---------------VKESGQEGSTDNDDSSSEKELGETNKGS 340
           +  Q+   G K   C+E               V  +G++     +   + K      K  
Sbjct: 399 RNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHK 458

Query: 341 CAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
                ++  KC+   G+A    S+ A  K+  + +KP  C ECGKAFR    L  H  +H
Sbjct: 459 VIHTREKLYKCEEC-GKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIH 517

Query: 398 KKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDK 457
                           G +P  C  +         A+ R              + IH  K
Sbjct: 518 ---------------TGEKPYKCE-ECGKAFSHFSALRR-------------HKIIHTGK 548

Query: 458 -----NDDGGKIKHLTSSR------------ECSYCGKFFRSNYYLNIHLRTHTGEKPYK 500
                 + G    H ++ R            +C  CGK F+ +  L +H   HT EKP K
Sbjct: 549 KPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCK 608

Query: 501 CEFCEYAAAQKTSLRYHLERHHKEK 525
           CE C  +    ++LR H   H +EK
Sbjct: 609 CEECGKSFKHFSALRKHKVIHTREK 633



 Score = 98.2 bits (243), Expect = 4e-20
 Identities = 115/480 (23%), Positives = 177/480 (36%), Gaps = 72/480 (15%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+H   L +H ++    +P  CE         + S L + ++     
Sbjct: 519 GEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFS--HFSALRRHKII---- 572

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
              +  E  + CE CG+ F+ +  + +H   H       C  CG+ FK    L+ H   H
Sbjct: 573 ---HTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIH 629

Query: 179 NGKSGARSKLQQGLESSPA--TINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRK 236
                 R KL +  E   A  + + +++     +   PYK C  CG  F     L  H+ 
Sbjct: 630 T-----REKLYKCEECVKAFNSFSALMKHKVIHTGEKPYK-CEECGKAFKWSSKLTVHKV 683

Query: 237 VHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDP 292
           +HT                G  P   E+  + F     LR      TGKKP +C      
Sbjct: 684 IHT----------------GEKPCKCEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKA 727

Query: 293 FTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCK 352
           F+   + +           E+  SG++     +   + K L +         +++  KC+
Sbjct: 728 FSQSSSLRK---------HEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCE 778

Query: 353 HSHGEAPSVDA--DPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTM 410
                     A    K+  + +KP  C ECGKAF     L+ H  +H             
Sbjct: 779 ECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHT------------ 826

Query: 411 SVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKH-LTS 469
              G++P  C+ +      ++  + R +     G +    E    D N+     KH L  
Sbjct: 827 ---GKKPYKCA-ECGKAFKQSSHLTRHKA-IHTGEKPYKCEECGKDFNNSSTLKKHKLIH 881

Query: 470 SRE----CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           +RE    C  C K F +   L  H   HTGEKPYKCE C  A    + L  H   H  EK
Sbjct: 882 TREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEK 941



 Score = 97.8 bits (242), Expect = 5e-20
 Identities = 125/550 (22%), Positives = 196/550 (35%), Gaps = 130/550 (23%)

Query: 48  FRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSP 107
           F     +N ++        C+ CS++F     L +H  +  R  + +        +  S 
Sbjct: 30  FHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFST 89

Query: 108 LDKSQV---RTEPPKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIH 146
           L K ++     +P K K C                   E  F CE CG+ F  + ++  H
Sbjct: 90  LTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDH 149

Query: 147 MRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVH 206
            R H    TY C  CG+ FK                              +  N    +H
Sbjct: 150 KRIHTGEKTYKCEECGKAFK----------------------------GSSNFNAHKVIH 181

Query: 207 AAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSRED-- 264
            AE    PYK C  CG  F +  +L +H+ +HT                G  P  RE+  
Sbjct: 182 TAE---KPYK-CEDCGKTFNHFSALRKHKIIHT----------------GKKPYKREECG 221

Query: 265 --FLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGST 322
             F Q   LR      TG+KP +C          +A++ ++K  V    +V  +G++   
Sbjct: 222 KAFSQSSTLRKHEIIHTGEKPYKC------EECGKAFKWSSKLTV---HKVVHTGEKPYK 272

Query: 323 DNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTHCSE 379
             +   +  +     K       ++  KC+   G+A    S     K+  + EKP  C E
Sbjct: 273 CEECGKAFSQFSTLKKHKIIHTGKKPYKCEEC-GKAFNSSSTLMKHKIIHTGEKPYKCEE 331

Query: 380 CGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVD-------------GRQPGTCSP---- 422
           CGKAFR    L  H  +H  ++    E    + +             G++P  C      
Sbjct: 332 CGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKA 391

Query: 423 -DLAAPLDENGAVDRGE---------GGSEDGSEDGLPEGIHLDK-----NDDGGKIKHL 467
              ++ L  +  +  GE            +  S+  + + IH  +      + G   KH 
Sbjct: 392 FSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHF 451

Query: 468 TSSR------------ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLR 515
           ++ R            +C  CGK F ++  L  H   HTG+KPYKCE C  A  Q + L 
Sbjct: 452 SALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLT 511

Query: 516 YHLERHHKEK 525
            H   H  EK
Sbjct: 512 RHKAIHTGEK 521



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 125/492 (25%), Positives = 175/492 (35%), Gaps = 96/492 (19%)

Query: 42   GTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLR 99
            G A   F A ++  VI   G  P  C  C + F+ S  L KH ++    +P  CE     
Sbjct: 697  GKAFKHFSALRKHKVIHT-GKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKA 755

Query: 100  VEAEYLSPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
             +  +LS L   +V      EK CK     CE CG+ F+    +  H   H     Y C 
Sbjct: 756  FK--WLSKLTVHKVIHTA--EKPCK-----CEECGKAFKHFSALRKHKIIHTGKKPYKCE 806

Query: 160  MCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICM 219
             CG+ F +   L  H   H GK   +           + +     +H  E    PYK C 
Sbjct: 807  ECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEK---PYK-CE 862

Query: 220  VCGFLFPNKESLIEHRKVHTKKT---------AFGTSSAQTDSP---QGGMPSSREDFLQ 267
             CG  F N  +L +H+ +HT++          AF   SA         G  P   E+  +
Sbjct: 863  ECGKDFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGK 922

Query: 268  LFNLRPK--SHP--ETGKKPVRCIPQLDPFTTFQAWQ----LATKGKVAICQEVKESGQE 319
             F    K   H    TG+KP +C      F  F A +    + T  K   C E  ++   
Sbjct: 923  AFKWSSKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNN 982

Query: 320  GSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTH 376
             ST               K       ++  KC+   G+A    S+    K+  S EKP  
Sbjct: 983  SST-------------LTKHKIIHTGEKPYKCEEC-GKAFSQSSILTKHKIIHSVEKPYK 1028

Query: 377  CSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDR 436
            C ECGKAF     L  H  +H                G +P  C     A +  +  +  
Sbjct: 1029 CEECGKAFNQSSHLTRHKTIH---------------TGEKPYKCEECGKAFIQCSYLIRH 1073

Query: 437  GEGGSEDGSEDGLPEGIHL-DKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTG 495
                          + IH  +K  +  K+  L              SN +  +    HTG
Sbjct: 1074 --------------KTIHTREKPTNVKKVPKLL-------------SNPHTLLDKTIHTG 1106

Query: 496  EKPYKCEFCEYA 507
            EKPYKCE C  A
Sbjct: 1107 EKPYKCEECAKA 1118



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 49/180 (27%), Positives = 72/180 (40%), Gaps = 17/180 (9%)

Query: 48   FRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYL 105
            F A ++  VI   G  P  C  C + F +S  L KH ++    +P  CE        E  
Sbjct: 955  FSALRKHKVIHT-GKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCE--------ECG 1005

Query: 106  SPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRF 165
                +S + T+  K  +  E  + CE CG+ F  +  +  H   H     Y C  CG+ F
Sbjct: 1006 KAFSQSSILTKH-KIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAF 1064

Query: 166  KEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLF 225
             +  +L  H   H  +     K    L S+P T+ +   +H  E    PYK C  C   F
Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKT-IHTGE---KPYK-CEECAKAF 1119


>gi|239746221 PREDICTED: hypothetical protein XP_002343677 [Homo
            sapiens]
          Length = 1119

 Score =  119 bits (297), Expect = 2e-26
 Identities = 131/506 (25%), Positives = 198/506 (39%), Gaps = 66/506 (13%)

Query: 64   PLDCMFCSQTFTHSEDLNKHVLMQHRPTL--CEPAVLRVEAEYLSPLDKSQVRTEPPKEK 121
            P  C  C ++F H   L KH ++  R  L  CE  V    +   S L K +V        
Sbjct: 606  PCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNS--FSALMKHKVI------- 656

Query: 122  NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
            +  E  + CE CG+ F+ +  + +H   H       C  CG+ FK    L+ H   H GK
Sbjct: 657  HTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGK 716

Query: 182  SGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKK 241
               + +      S  +++ +   +H+ E    PYK C  CG  F     L  H+ +HT +
Sbjct: 717  KPYKCEECGKAFSQSSSLRKHEIIHSGEK---PYK-CEECGKAFKWLSKLTVHKVIHTAE 772

Query: 242  T---------AFGTSSAQTDSP---QGGMPSSREDFLQLFN----LRPKSHPETGKKPVR 285
                      AF   SA         G  P   E+  + FN    L       TGKKP +
Sbjct: 773  KPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYK 832

Query: 286  CIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLS 345
            C    +    F+     T+ K     E     +E   D ++SS+ K      K       
Sbjct: 833  CA---ECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLK------KHKLIHTR 883

Query: 346  QEKEKCKHSHGEAPSVDA--DPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRA 403
            ++  KC+       +  A    K+  + EKP  C ECGKAF+   +L  H  +H  ++  
Sbjct: 884  EKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPC 943

Query: 404  GAESPTMSV-------------DGRQPGTCSP-----DLAAPLDENGAVDRGEGGSE-DG 444
              E    +               G++P  C       + ++ L ++  +  GE   + + 
Sbjct: 944  KCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEE 1003

Query: 445  SEDGLPEGIHLDKNDDGGKIKH-LTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEF 503
                  +   L K+    KI H +    +C  CGK F  + +L  H   HTGEKPYKCE 
Sbjct: 1004 CGKAFSQSSILTKH----KIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEE 1059

Query: 504  CEYAAAQKTSLRYHLERHHKEKQTDV 529
            C  A  Q + L  H   H +EK T+V
Sbjct: 1060 CGKAFIQCSYLIRHKTIHTREKPTNV 1085



 Score =  112 bits (280), Expect = 2e-24
 Identities = 123/505 (24%), Positives = 183/505 (36%), Gaps = 100/505 (19%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNC 123
           P  C  C +TF H   L KH ++       +           S L K ++        + 
Sbjct: 186 PYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEII-------HT 238

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
            E  + CE CG+ F+ +  + +H   H     Y C  CG+ F +   LK H   H GK  
Sbjct: 239 GEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKP 298

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTA 243
            + +      +S +T+ +   +H  E    PYK C  CG  F     L  H+ +HT    
Sbjct: 299 YKCEECGKAFNSSSTLMKHKIIHTGE---KPYK-CEECGKAFRQSSHLTRHKAIHT---- 350

Query: 244 FGTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDPF---TTF 296
                       G  P   E+  + FN    LR      TGKKP +C      F   +T 
Sbjct: 351 ------------GEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSSTL 398

Query: 297 QAWQLATKG-KVAICQE---------------VKESGQEGSTDNDDSSSEKELGETNKGS 340
           +  Q+   G K   C+E               V  +G++     +   + K      K  
Sbjct: 399 RNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHK 458

Query: 341 CAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
                ++  KC+   G+A    S+ A  K+  + +KP  C ECGKAFR    L  H  +H
Sbjct: 459 VIHTREKLYKCEEC-GKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIH 517

Query: 398 KKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDK 457
                           G +P  C  +         A+ R              + IH  K
Sbjct: 518 ---------------TGEKPYKCE-ECGKAFSHFSALRR-------------HKIIHTGK 548

Query: 458 -----NDDGGKIKHLTSSR------------ECSYCGKFFRSNYYLNIHLRTHTGEKPYK 500
                 + G    H ++ R            +C  CGK F+ +  L +H   HT EKP K
Sbjct: 549 KPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCK 608

Query: 501 CEFCEYAAAQKTSLRYHLERHHKEK 525
           CE C  +    ++LR H   H +EK
Sbjct: 609 CEECGKSFKHFSALRKHKVIHTREK 633



 Score = 98.2 bits (243), Expect = 4e-20
 Identities = 115/480 (23%), Positives = 177/480 (36%), Gaps = 72/480 (15%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+H   L +H ++    +P  CE         + S L + ++     
Sbjct: 519 GEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFS--HFSALRRHKII---- 572

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
              +  E  + CE CG+ F+ +  + +H   H       C  CG+ FK    L+ H   H
Sbjct: 573 ---HTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIH 629

Query: 179 NGKSGARSKLQQGLESSPA--TINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRK 236
                 R KL +  E   A  + + +++     +   PYK C  CG  F     L  H+ 
Sbjct: 630 T-----REKLYKCEECVKAFNSFSALMKHKVIHTGEKPYK-CEECGKAFKWSSKLTVHKV 683

Query: 237 VHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDP 292
           +HT                G  P   E+  + F     LR      TGKKP +C      
Sbjct: 684 IHT----------------GEKPCKCEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKA 727

Query: 293 FTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCK 352
           F+   + +           E+  SG++     +   + K L +         +++  KC+
Sbjct: 728 FSQSSSLRK---------HEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCE 778

Query: 353 HSHGEAPSVDA--DPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTM 410
                     A    K+  + +KP  C ECGKAF     L+ H  +H             
Sbjct: 779 ECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHT------------ 826

Query: 411 SVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKH-LTS 469
              G++P  C+ +      ++  + R +     G +    E    D N+     KH L  
Sbjct: 827 ---GKKPYKCA-ECGKAFKQSSHLTRHKA-IHTGEKPYKCEECGKDFNNSSTLKKHKLIH 881

Query: 470 SRE----CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           +RE    C  C K F +   L  H   HTGEKPYKCE C  A    + L  H   H  EK
Sbjct: 882 TREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEK 941



 Score = 97.8 bits (242), Expect = 5e-20
 Identities = 125/550 (22%), Positives = 196/550 (35%), Gaps = 130/550 (23%)

Query: 48  FRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSP 107
           F     +N ++        C+ CS++F     L +H  +  R  + +        +  S 
Sbjct: 30  FHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFST 89

Query: 108 LDKSQV---RTEPPKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIH 146
           L K ++     +P K K C                   E  F CE CG+ F  + ++  H
Sbjct: 90  LTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDH 149

Query: 147 MRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVH 206
            R H    TY C  CG+ FK                              +  N    +H
Sbjct: 150 KRIHTGEKTYKCEECGKAFK----------------------------GSSNFNAHKVIH 181

Query: 207 AAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSRED-- 264
            AE    PYK C  CG  F +  +L +H+ +HT                G  P  RE+  
Sbjct: 182 TAE---KPYK-CEDCGKTFNHFSALRKHKIIHT----------------GKKPYKREECG 221

Query: 265 --FLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGST 322
             F Q   LR      TG+KP +C          +A++ ++K  V    +V  +G++   
Sbjct: 222 KAFSQSSTLRKHEIIHTGEKPYKC------EECGKAFKWSSKLTV---HKVVHTGEKPYK 272

Query: 323 DNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTHCSE 379
             +   +  +     K       ++  KC+   G+A    S     K+  + EKP  C E
Sbjct: 273 CEECGKAFSQFSTLKKHKIIHTGKKPYKCEEC-GKAFNSSSTLMKHKIIHTGEKPYKCEE 331

Query: 380 CGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVD-------------GRQPGTCSP---- 422
           CGKAFR    L  H  +H  ++    E    + +             G++P  C      
Sbjct: 332 CGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKA 391

Query: 423 -DLAAPLDENGAVDRGE---------GGSEDGSEDGLPEGIHLDK-----NDDGGKIKHL 467
              ++ L  +  +  GE            +  S+  + + IH  +      + G   KH 
Sbjct: 392 FSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHF 451

Query: 468 TSSR------------ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLR 515
           ++ R            +C  CGK F ++  L  H   HTG+KPYKCE C  A  Q + L 
Sbjct: 452 SALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLT 511

Query: 516 YHLERHHKEK 525
            H   H  EK
Sbjct: 512 RHKAIHTGEK 521



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 125/492 (25%), Positives = 175/492 (35%), Gaps = 96/492 (19%)

Query: 42   GTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLR 99
            G A   F A ++  VI   G  P  C  C + F+ S  L KH ++    +P  CE     
Sbjct: 697  GKAFKHFSALRKHKVIHT-GKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKA 755

Query: 100  VEAEYLSPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
             +  +LS L   +V      EK CK     CE CG+ F+    +  H   H     Y C 
Sbjct: 756  FK--WLSKLTVHKVIHTA--EKPCK-----CEECGKAFKHFSALRKHKIIHTGKKPYKCE 806

Query: 160  MCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICM 219
             CG+ F +   L  H   H GK   +           + +     +H  E    PYK C 
Sbjct: 807  ECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEK---PYK-CE 862

Query: 220  VCGFLFPNKESLIEHRKVHTKKT---------AFGTSSAQTDSP---QGGMPSSREDFLQ 267
             CG  F N  +L +H+ +HT++          AF   SA         G  P   E+  +
Sbjct: 863  ECGKDFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGK 922

Query: 268  LFNLRPK--SHP--ETGKKPVRCIPQLDPFTTFQAWQ----LATKGKVAICQEVKESGQE 319
             F    K   H    TG+KP +C      F  F A +    + T  K   C E  ++   
Sbjct: 923  AFKWSSKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNN 982

Query: 320  GSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTH 376
             ST               K       ++  KC+   G+A    S+    K+  S EKP  
Sbjct: 983  SST-------------LTKHKIIHTGEKPYKCEEC-GKAFSQSSILTKHKIIHSVEKPYK 1028

Query: 377  CSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDR 436
            C ECGKAF     L  H  +H                G +P  C     A +  +  +  
Sbjct: 1029 CEECGKAFNQSSHLTRHKTIH---------------TGEKPYKCEECGKAFIQCSYLIRH 1073

Query: 437  GEGGSEDGSEDGLPEGIHL-DKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTG 495
                          + IH  +K  +  K+  L              SN +  +    HTG
Sbjct: 1074 --------------KTIHTREKPTNVKKVPKLL-------------SNPHTLLDKTIHTG 1106

Query: 496  EKPYKCEFCEYA 507
            EKPYKCE C  A
Sbjct: 1107 EKPYKCEECAKA 1118



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 49/180 (27%), Positives = 72/180 (40%), Gaps = 17/180 (9%)

Query: 48   FRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYL 105
            F A ++  VI   G  P  C  C + F +S  L KH ++    +P  CE        E  
Sbjct: 955  FSALRKHKVIHT-GKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCE--------ECG 1005

Query: 106  SPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRF 165
                +S + T+  K  +  E  + CE CG+ F  +  +  H   H     Y C  CG+ F
Sbjct: 1006 KAFSQSSILTKH-KIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAF 1064

Query: 166  KEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLF 225
             +  +L  H   H  +     K    L S+P T+ +   +H  E    PYK C  C   F
Sbjct: 1065 IQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKT-IHTGE---KPYK-CEECAKAF 1119


>gi|224548994 zinc finger protein 709 isoform b [Homo sapiens]
          Length = 609

 Score =  117 bits (294), Expect = 4e-26
 Identities = 115/476 (24%), Positives = 183/476 (38%), Gaps = 64/476 (13%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C + F +      H+ M    +P  C+                 +  + P 
Sbjct: 160 GEKPYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKEC--------------GKTFSHPS 205

Query: 119 KEKNCK-----ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKN 173
             +N +     E  + C+ CG+ FR     +IH RTH     Y C  CG+    P   ++
Sbjct: 206 SFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCPTSFRS 265

Query: 174 HMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIE 233
           H R H G+   + K      S P++  +  ++H  E    PY  C  CG  F +  S   
Sbjct: 266 HERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGE---KPYD-CKECGKAFISLPSYRR 321

Query: 234 HRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPF 293
           H  +HT     G    +        PSS       F +  ++H  TG+KP  C      F
Sbjct: 322 HMIMHTGN---GPYKCKECGKAFDCPSS-------FQIHERTH--TGEKPYECKQCGKAF 369

Query: 294 TTFQAWQLATKGKVA-ICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCK 352
           +   ++++  +        E K+ G+  S     SSS +    T+ G      ++  +CK
Sbjct: 370 SCSSSFRMHERTHTGEKPHECKQCGKAFSC----SSSVRIHERTHTG------EKPYECK 419

Query: 353 HSHGEAPSVDADPKLPS---SKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPT 409
              G+A S  +  ++     + EKP  C +CGKAF       +H R H        E P 
Sbjct: 420 QC-GKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHT------GEKPY 472

Query: 410 MSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTS 469
                 +  +CS       +     ++     + G        I + +    G+  +   
Sbjct: 473 ECKQCGKAFSCSSSFRMH-ERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPY--- 528

Query: 470 SRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
             EC  CGK F  +  + +H RTHTG KPY+C+ C+ A +   S R H   H  EK
Sbjct: 529 --ECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEK 582



 Score =  107 bits (266), Expect = 8e-23
 Identities = 105/465 (22%), Positives = 166/465 (35%), Gaps = 66/465 (14%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNC 123
           P +C  C + +     LN+H+                         +S       +    
Sbjct: 69  PYECSVCGKDYMCHSSLNRHM-------------------------RSHTEHRSYEYHKY 103

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
            E  + C+ CG+ F       IH RTH     Y C  CG+ F  P   + H RTH G+  
Sbjct: 104 GEKSYECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKP 163

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTA 243
              K          T    +++H  E    PYK C  CG  F +  S   H + H+ +  
Sbjct: 164 YECKECGKAFIYHTTFRGHMRMHTGEK---PYK-CKECGKTFSHPSSFRNHERTHSGEKP 219

Query: 244 FGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIP---QLDPFTTFQAWQ 300
           +       +  Q G       + Q F +  ++H  TG+KP +C      L   T+F++ +
Sbjct: 220 Y-------ECKQCGKAFR---YYQTFQIHERTH--TGEKPYQCKQCGKALSCPTSFRSHE 267

Query: 301 LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPS 360
               G+     + K+ G+  S  +     E+         C       ++C  +    PS
Sbjct: 268 RIHTGEKPY--KCKKCGKAFSFPSSFRKHERIHTGEKPYDC-------KECGKAFISLPS 318

Query: 361 VDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTC 420
                 +  +   P  C ECGKAF       +H R H        E P       +  +C
Sbjct: 319 YRRH-MIMHTGNGPYKCKECGKAFDCPSSFQIHERTHT------GEKPYECKQCGKAFSC 371

Query: 421 SPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFF 480
           S       +     ++     + G        + + +    G+  +     EC  CGK F
Sbjct: 372 SSSFRMH-ERTHTGEKPHECKQCGKAFSCSSSVRIHERTHTGEKPY-----ECKQCGKAF 425

Query: 481 RSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
             +    +H R HTGEKPY+C+ C  A +  +S R H   H  EK
Sbjct: 426 SCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHTGEK 470



 Score =  100 bits (249), Expect = 7e-21
 Identities = 109/456 (23%), Positives = 162/456 (35%), Gaps = 73/456 (16%)

Query: 92  LCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHK 151
           LCE    R E              +P K+   +   + C VCG+ +     +  HMR+H 
Sbjct: 38  LCE----RKEGSQFGETISQTPNPKPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSHT 93

Query: 152 D----------SFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINE 201
           +            +Y C  CG+RF      + H RTH G+   + K      S P++   
Sbjct: 94  EHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQI 153

Query: 202 VVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSS 261
             + H  E    PY+ C  CG  F    +   H ++HT +  +                 
Sbjct: 154 HERTHTGE---KPYE-CKECGKAFIYHTTFRGHMRMHTGEKPYKCKEC------------ 197

Query: 262 REDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVA-ICQEVKESGQEG 320
            + F    + R      +G+KP  C      F  +Q +Q+  +        + K+ G+  
Sbjct: 198 GKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKAL 257

Query: 321 STDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTHC 377
           S      S E+              ++  KCK   G+A   PS     +   + EKP  C
Sbjct: 258 SCPTSFRSHER----------IHTGEKPYKCKKC-GKAFSFPSSFRKHERIHTGEKPYDC 306

Query: 378 SECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSP-----DLAAPLDENG 432
            ECGKAF +      H  +H                G  P  C       D  +    + 
Sbjct: 307 KECGKAFISLPSYRRHMIMH---------------TGNGPYKCKECGKAFDCPSSFQIHE 351

Query: 433 AVDRGEGGSE---DGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIH 489
               GE   E    G          + +    G+  H     EC  CGK F  +  + IH
Sbjct: 352 RTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPH-----ECKQCGKAFSCSSSVRIH 406

Query: 490 LRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
            RTHTGEKPY+C+ C  A +  +S R H   H  EK
Sbjct: 407 ERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEK 442



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 80/340 (23%), Positives = 129/340 (37%), Gaps = 36/340 (10%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P DC  C + F       +H++M   + P  C+      +      + +     E P
Sbjct: 300 GEKPYDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKP 359

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
            E         C+ CG+ F  +    +H RTH     + C  CG+ F     ++ H RTH
Sbjct: 360 YE---------CKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTH 410

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+     K      S  ++     ++H  E    PY+ C  CG  F    S   H + H
Sbjct: 411 TGEKPYECKQCGKAFSCSSSFRMHERIHTGEK---PYE-CKQCGKAFSFSSSFRMHERTH 466

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
           T +  +       +  Q G   S       F +  ++H  TG+KP  C      F+   +
Sbjct: 467 TGEKPY-------ECKQCGKAFSCSSS---FRMHERTH--TGEKPYECKQCGKAFSCSSS 514

Query: 299 WQLATKGKVAICQ-EVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGE 357
            ++  +        E K+ G+  S     SSS +    T+ G       E ++C  +   
Sbjct: 515 IRIHERTHTGEKPYECKQCGKAFSC----SSSVRMHERTHTGV---KPYECKQCDKAFSC 567

Query: 358 APSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
           + S     +  +  EKP  C +CGKAF+      +H RVH
Sbjct: 568 SRSFRIHERTHTG-EKPYACQQCGKAFKCSRSFRIHERVH 606



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 47/181 (25%), Positives = 67/181 (37%), Gaps = 15/181 (8%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C + F+ S     H       +P  C+      +A   S   +   RT   
Sbjct: 440 GEKPYECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCG---KAFSCSSSFRMHERT--- 493

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
              +  E  + C+ CG+ F  +  + IH RTH     Y C  CG+ F     ++ H RTH
Sbjct: 494 ---HTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTH 550

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G      K      S   +     + H  E    PY  C  CG  F    S   H +VH
Sbjct: 551 TGVKPYECKQCDKAFSCSRSFRIHERTHTGE---KPY-ACQQCGKAFKCSRSFRIHERVH 606

Query: 239 T 239
           +
Sbjct: 607 S 607



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 43/165 (26%), Positives = 60/165 (36%), Gaps = 28/165 (16%)

Query: 372 EKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCS--------PD 423
           EKP  C ECGKAF  +     H R+H                G +P  C         P 
Sbjct: 161 EKPYECKECGKAFIYHTTFRGHMRMHT---------------GEKPYKCKECGKTFSHPS 205

Query: 424 LAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSN 483
                +   + ++     + G      +   + +    G+  +     +C  CGK     
Sbjct: 206 SFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPY-----QCKQCGKALSCP 260

Query: 484 YYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTD 528
                H R HTGEKPYKC+ C  A +  +S R H   H  EK  D
Sbjct: 261 TSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKPYD 305



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 32/123 (26%), Positives = 45/123 (36%), Gaps = 11/123 (8%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C + F+ S  +  H       +P  C+                S VR    
Sbjct: 496 GEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCS-------SSVRMHER 548

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
                K  E  C+ C + F  +    IH RTH     Y C  CG+ FK     + H R H
Sbjct: 549 THTGVKPYE--CKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFKCSRSFRIHERVH 606

Query: 179 NGK 181
           +G+
Sbjct: 607 SGE 609


>gi|22749235 zinc finger protein 709 isoform a [Homo sapiens]
          Length = 641

 Score =  117 bits (294), Expect = 4e-26
 Identities = 115/476 (24%), Positives = 183/476 (38%), Gaps = 64/476 (13%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C + F +      H+ M    +P  C+                 +  + P 
Sbjct: 192 GEKPYECKECGKAFIYHTTFRGHMRMHTGEKPYKCKEC--------------GKTFSHPS 237

Query: 119 KEKNCK-----ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKN 173
             +N +     E  + C+ CG+ FR     +IH RTH     Y C  CG+    P   ++
Sbjct: 238 SFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKALSCPTSFRS 297

Query: 174 HMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIE 233
           H R H G+   + K      S P++  +  ++H  E    PY  C  CG  F +  S   
Sbjct: 298 HERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGE---KPYD-CKECGKAFISLPSYRR 353

Query: 234 HRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPF 293
           H  +HT     G    +        PSS       F +  ++H  TG+KP  C      F
Sbjct: 354 HMIMHTGN---GPYKCKECGKAFDCPSS-------FQIHERTH--TGEKPYECKQCGKAF 401

Query: 294 TTFQAWQLATKGKVA-ICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCK 352
           +   ++++  +        E K+ G+  S     SSS +    T+ G      ++  +CK
Sbjct: 402 SCSSSFRMHERTHTGEKPHECKQCGKAFSC----SSSVRIHERTHTG------EKPYECK 451

Query: 353 HSHGEAPSVDADPKLPS---SKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPT 409
              G+A S  +  ++     + EKP  C +CGKAF       +H R H        E P 
Sbjct: 452 QC-GKAFSCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHT------GEKPY 504

Query: 410 MSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTS 469
                 +  +CS       +     ++     + G        I + +    G+  +   
Sbjct: 505 ECKQCGKAFSCSSSFRMH-ERTHTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPY--- 560

Query: 470 SRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
             EC  CGK F  +  + +H RTHTG KPY+C+ C+ A +   S R H   H  EK
Sbjct: 561 --ECKQCGKAFSCSSSVRMHERTHTGVKPYECKQCDKAFSCSRSFRIHERTHTGEK 614



 Score =  107 bits (266), Expect = 8e-23
 Identities = 105/465 (22%), Positives = 166/465 (35%), Gaps = 66/465 (14%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNC 123
           P +C  C + +     LN+H+                         +S       +    
Sbjct: 101 PYECSVCGKDYMCHSSLNRHM-------------------------RSHTEHRSYEYHKY 135

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
            E  + C+ CG+ F       IH RTH     Y C  CG+ F  P   + H RTH G+  
Sbjct: 136 GEKSYECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQIHERTHTGEKP 195

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTA 243
              K          T    +++H  E    PYK C  CG  F +  S   H + H+ +  
Sbjct: 196 YECKECGKAFIYHTTFRGHMRMHTGEK---PYK-CKECGKTFSHPSSFRNHERTHSGEKP 251

Query: 244 FGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIP---QLDPFTTFQAWQ 300
           +       +  Q G       + Q F +  ++H  TG+KP +C      L   T+F++ +
Sbjct: 252 Y-------ECKQCGKAFR---YYQTFQIHERTH--TGEKPYQCKQCGKALSCPTSFRSHE 299

Query: 301 LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPS 360
               G+     + K+ G+  S  +     E+         C       ++C  +    PS
Sbjct: 300 RIHTGEKPY--KCKKCGKAFSFPSSFRKHERIHTGEKPYDC-------KECGKAFISLPS 350

Query: 361 VDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTC 420
                 +  +   P  C ECGKAF       +H R H        E P       +  +C
Sbjct: 351 YRRH-MIMHTGNGPYKCKECGKAFDCPSSFQIHERTHT------GEKPYECKQCGKAFSC 403

Query: 421 SPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFF 480
           S       +     ++     + G        + + +    G+  +     EC  CGK F
Sbjct: 404 SSSFRMH-ERTHTGEKPHECKQCGKAFSCSSSVRIHERTHTGEKPY-----ECKQCGKAF 457

Query: 481 RSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
             +    +H R HTGEKPY+C+ C  A +  +S R H   H  EK
Sbjct: 458 SCSSSFRMHERIHTGEKPYECKQCGKAFSFSSSFRMHERTHTGEK 502



 Score =  100 bits (249), Expect = 7e-21
 Identities = 109/456 (23%), Positives = 162/456 (35%), Gaps = 73/456 (16%)

Query: 92  LCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHK 151
           LCE    R E              +P K+   +   + C VCG+ +     +  HMR+H 
Sbjct: 70  LCE----RKEGSQFGETISQTPNPKPNKKTFTRVKPYECSVCGKDYMCHSSLNRHMRSHT 125

Query: 152 D----------SFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINE 201
           +            +Y C  CG+RF      + H RTH G+   + K      S P++   
Sbjct: 126 EHRSYEYHKYGEKSYECKECGKRFSFRSSFRIHERTHTGEKPYKCKQCGKAFSWPSSFQI 185

Query: 202 VVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSS 261
             + H  E    PY+ C  CG  F    +   H ++HT +  +                 
Sbjct: 186 HERTHTGE---KPYE-CKECGKAFIYHTTFRGHMRMHTGEKPYKCKEC------------ 229

Query: 262 REDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVA-ICQEVKESGQEG 320
            + F    + R      +G+KP  C      F  +Q +Q+  +        + K+ G+  
Sbjct: 230 GKTFSHPSSFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPYQCKQCGKAL 289

Query: 321 STDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDADPKLPSSKEKPTHC 377
           S      S E+              ++  KCK   G+A   PS     +   + EKP  C
Sbjct: 290 SCPTSFRSHER----------IHTGEKPYKCKKC-GKAFSFPSSFRKHERIHTGEKPYDC 338

Query: 378 SECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSP-----DLAAPLDENG 432
            ECGKAF +      H  +H                G  P  C       D  +    + 
Sbjct: 339 KECGKAFISLPSYRRHMIMH---------------TGNGPYKCKECGKAFDCPSSFQIHE 383

Query: 433 AVDRGEGGSE---DGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIH 489
               GE   E    G          + +    G+  H     EC  CGK F  +  + IH
Sbjct: 384 RTHTGEKPYECKQCGKAFSCSSSFRMHERTHTGEKPH-----ECKQCGKAFSCSSSVRIH 438

Query: 490 LRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
            RTHTGEKPY+C+ C  A +  +S R H   H  EK
Sbjct: 439 ERTHTGEKPYECKQCGKAFSCSSSFRMHERIHTGEK 474



 Score = 78.6 bits (192), Expect = 3e-14
 Identities = 80/340 (23%), Positives = 129/340 (37%), Gaps = 36/340 (10%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P DC  C + F       +H++M   + P  C+      +      + +     E P
Sbjct: 332 GEKPYDCKECGKAFISLPSYRRHMIMHTGNGPYKCKECGKAFDCPSSFQIHERTHTGEKP 391

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
            E         C+ CG+ F  +    +H RTH     + C  CG+ F     ++ H RTH
Sbjct: 392 YE---------CKQCGKAFSCSSSFRMHERTHTGEKPHECKQCGKAFSCSSSVRIHERTH 442

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+     K      S  ++     ++H  E    PY+ C  CG  F    S   H + H
Sbjct: 443 TGEKPYECKQCGKAFSCSSSFRMHERIHTGEK---PYE-CKQCGKAFSFSSSFRMHERTH 498

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
           T +  +       +  Q G   S       F +  ++H  TG+KP  C      F+   +
Sbjct: 499 TGEKPY-------ECKQCGKAFSCSSS---FRMHERTH--TGEKPYECKQCGKAFSCSSS 546

Query: 299 WQLATKGKVAICQ-EVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGE 357
            ++  +        E K+ G+  S     SSS +    T+ G       E ++C  +   
Sbjct: 547 IRIHERTHTGEKPYECKQCGKAFSC----SSSVRMHERTHTGV---KPYECKQCDKAFSC 599

Query: 358 APSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
           + S     +  +  EKP  C +CGKAF+      +H RVH
Sbjct: 600 SRSFRIHERTHTG-EKPYACQQCGKAFKCSRSFRIHERVH 638



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 47/181 (25%), Positives = 67/181 (37%), Gaps = 15/181 (8%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C + F+ S     H       +P  C+      +A   S   +   RT   
Sbjct: 472 GEKPYECKQCGKAFSFSSSFRMHERTHTGEKPYECKQCG---KAFSCSSSFRMHERT--- 525

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
              +  E  + C+ CG+ F  +  + IH RTH     Y C  CG+ F     ++ H RTH
Sbjct: 526 ---HTGEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCSSSVRMHERTH 582

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G      K      S   +     + H  E    PY  C  CG  F    S   H +VH
Sbjct: 583 TGVKPYECKQCDKAFSCSRSFRIHERTHTGE---KPY-ACQQCGKAFKCSRSFRIHERVH 638

Query: 239 T 239
           +
Sbjct: 639 S 639



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 43/165 (26%), Positives = 60/165 (36%), Gaps = 28/165 (16%)

Query: 372 EKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCS--------PD 423
           EKP  C ECGKAF  +     H R+H                G +P  C         P 
Sbjct: 193 EKPYECKECGKAFIYHTTFRGHMRMHT---------------GEKPYKCKECGKTFSHPS 237

Query: 424 LAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSN 483
                +   + ++     + G      +   + +    G+  +     +C  CGK     
Sbjct: 238 SFRNHERTHSGEKPYECKQCGKAFRYYQTFQIHERTHTGEKPY-----QCKQCGKALSCP 292

Query: 484 YYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQTD 528
                H R HTGEKPYKC+ C  A +  +S R H   H  EK  D
Sbjct: 293 TSFRSHERIHTGEKPYKCKKCGKAFSFPSSFRKHERIHTGEKPYD 337



 Score = 47.0 bits (110), Expect = 9e-05
 Identities = 32/123 (26%), Positives = 45/123 (36%), Gaps = 11/123 (8%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C + F+ S  +  H       +P  C+                S VR    
Sbjct: 528 GEKPYECKQCGKAFSCSSSIRIHERTHTGEKPYECKQCGKAFSCS-------SSVRMHER 580

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
                K  E  C+ C + F  +    IH RTH     Y C  CG+ FK     + H R H
Sbjct: 581 THTGVKPYE--CKQCDKAFSCSRSFRIHERTHTGEKPYACQQCGKAFKCSRSFRIHERVH 638

Query: 179 NGK 181
           +G+
Sbjct: 639 SGE 641


>gi|110626177 zinc finger protein 699 [Homo sapiens]
          Length = 642

 Score =  115 bits (289), Expect = 2e-25
 Identities = 113/478 (23%), Positives = 179/478 (37%), Gaps = 78/478 (16%)

Query: 66  DCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNC 123
           +C  C + F     L  H+      +P  C+      +A +     K  ++T P +EK  
Sbjct: 196 ECHECGKAFVDHSSLKSHIRSHTGSKPYQCKECG---KAFHFLACFKKHMKT-PTEEK-- 249

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
               + C+ C + F  +     HM+ H     Y C  CG+ F     L  H R H+G   
Sbjct: 250 ---PYECKECTKAFSCSSFFRAHMKIHIGKTNYECKECGKGFSCSSSLTEHKRIHSGDKP 306

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKT- 242
              K      S  +++++  ++H+ +    PY+ C  CG  F +   LI H ++HT +  
Sbjct: 307 YECKECGKAFSCSSSLSKHKRIHSGDK---PYE-CKECGKAFSSSSHLIIHIRIHTGEKP 362

Query: 243 --------AFGTSSAQT---DSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCI 287
                   AF  SS  T    +  G  P   ++  + +N    L       TG+KP  C+
Sbjct: 363 YECKECGKAFSESSKLTVHGRTHTGEKPYKCKECGKAYNCPSSLSIHMRKHTGEKPYECL 422

Query: 288 PQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQE 347
                    +A+ L T     +  + +E   E        S         +     +  E
Sbjct: 423 E------CGKAFYLPTSLNTHVKNQSREKPYECKECGKAFSCPSSFRAHVRDHTGKIQYE 476

Query: 348 KEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAES 407
            ++C  +   + S+    +  S  EKP  C ECGKAF +   L +H R H          
Sbjct: 477 CKECGKTFSRSSSLTEHLRTHSG-EKPYECKECGKAFISSSHLTVHIRTHT--------- 526

Query: 408 PTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHL 467
                 G +P  C                     + G     P  + +      G+  + 
Sbjct: 527 ------GEKPYECK--------------------KCGKAFIYPSALRIHMRTHTGEKPY- 559

Query: 468 TSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
               EC  CGK FR + YL +H R HTGEKP++C  C  A +  +S R H+  H  EK
Sbjct: 560 ----ECKECGKAFRHSSYLTVHARMHTGEKPFECLECGKAFSCPSSFRRHVRSHTGEK 613



 Score =  108 bits (269), Expect = 3e-23
 Identities = 113/449 (25%), Positives = 177/449 (39%), Gaps = 103/449 (22%)

Query: 111 SQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRF----- 165
           SQV      ++N +     C  CG+ F     ++ H+R+H  S  Y C  CG+ F     
Sbjct: 178 SQVPNLDSLKRNTEVKSCECHECGKAFVDHSSLKSHIRSHTGSKPYQCKECGKAFHFLAC 237

Query: 166 ----------KEPW-------------FLKNHMRTHNGKSGARSKLQQGLESSPATINEV 202
                     ++P+             F + HM+ H GK+    K      S  +++ E 
Sbjct: 238 FKKHMKTPTEEKPYECKECTKAFSCSSFFRAHMKIHIGKTNYECKECGKGFSCSSSLTEH 297

Query: 203 VQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSR 262
            ++H+ +    PY+ C  CG  F    SL +H+++H+    +       +  + G   S 
Sbjct: 298 KRIHSGD---KPYE-CKECGKAFSCSSSLSKHKRIHSGDKPY-------ECKECGKAFSS 346

Query: 263 EDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGST 322
              L + ++R      TG+KP  C                           KE G+  S 
Sbjct: 347 SSHL-IIHIR----IHTGEKPYEC---------------------------KECGKAFS- 373

Query: 323 DNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSK---EKPTHCSE 379
              +SS     G T+ G      ++  KCK   G+A +  +   +   K   EKP  C E
Sbjct: 374 ---ESSKLTVHGRTHTG------EKPYKCKEC-GKAYNCPSSLSIHMRKHTGEKPYECLE 423

Query: 380 CGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPL-DENGAV--DR 436
           CGKAF  Y    L++ V  + R    E P    +  +  +C     A + D  G +  + 
Sbjct: 424 CGKAF--YLPTSLNTHVKNQSR----EKPYECKECGKAFSCPSSFRAHVRDHTGKIQYEC 477

Query: 437 GEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGE 496
            E G        L E +     +            EC  CGK F S+ +L +H+RTHTGE
Sbjct: 478 KECGKTFSRSSSLTEHLRTHSGE---------KPYECKECGKAFISSSHLTVHIRTHTGE 528

Query: 497 KPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           KPY+C+ C  A    ++LR H+  H  EK
Sbjct: 529 KPYECKKCGKAFIYPSALRIHMRTHTGEK 557



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 54/229 (23%), Positives = 85/229 (37%), Gaps = 55/229 (24%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
           G  P +C+ C + F     LN HV                         K+Q R +P   
Sbjct: 415 GEKPYECLECGKAFYLPTSLNTHV-------------------------KNQSREKP--- 446

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
                  + C+ CG+ F        H+R H     Y C  CG+ F     L  H+RTH+G
Sbjct: 447 -------YECKECGKAFSCPSSFRAHVRDHTGKIQYECKECGKTFSRSSSLTEHLRTHSG 499

Query: 181 KSGARSKL--QQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
           +     K   +  + SS  T++  ++ H  E    PY+ C  CG  F    +L  H + H
Sbjct: 500 EKPYECKECGKAFISSSHLTVH--IRTHTGE---KPYE-CKKCGKAFIYPSALRIHMRTH 553

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCI 287
           T +  +       +  + G       +L +      +   TG+KP  C+
Sbjct: 554 TGEKPY-------ECKECGKAFRHSSYLTV-----HARMHTGEKPFECL 590



 Score = 57.8 bits (138), Expect = 5e-08
 Identities = 40/172 (23%), Positives = 69/172 (40%), Gaps = 21/172 (12%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLC-EPAVLRVEAEYLSPLDKSQVRTEP 117
           G +  +C  C +TF+ S  L +H+      +P  C E     + + +L+   ++    +P
Sbjct: 471 GKIQYECKECGKTFSRSSSLTEHLRTHSGEKPYECKECGKAFISSSHLTVHIRTHTGEKP 530

Query: 118 PKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
            + K C                   E  + C+ CG+ FR +  + +H R H     + C 
Sbjct: 531 YECKKCGKAFIYPSALRIHMRTHTGEKPYECKECGKAFRHSSYLTVHARMHTGEKPFECL 590

Query: 160 MCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESI 211
            CG+ F  P   + H+R+H G+     K        PA     V+ H  E+I
Sbjct: 591 ECGKAFSCPSSFRRHVRSHTGEKPYECKECGKAFVCPAYFRRHVKTHTRENI 642


>gi|190570172 zinc finger protein 180 [Homo sapiens]
          Length = 692

 Score =  114 bits (286), Expect = 4e-25
 Identities = 105/405 (25%), Positives = 156/405 (38%), Gaps = 65/405 (16%)

Query: 122 NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
           N +E  F C  CG++F  +  +  H RTH     Y C+ CG+ F     L +H RTH G+
Sbjct: 347 NSEEKPFECNQCGKSFSWSSHLVAHQRTHTGEKPYECSECGKSFSRSSHLVSHQRTHTGE 406

Query: 182 SGARSKLQQGLESSPATINEVVQ-VHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
              R   Q G   S + +  V Q  H  E    PY+ C  CG  F     LI H++ HT 
Sbjct: 407 KPYRCN-QCGKSFSQSYVLVVHQRTHTGE---KPYE-CNQCGKSFRQSYKLIAHQRTHTG 461

Query: 241 KTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQ 300
           +  +  +               + F+Q + L       TG+KP  C      F+  Q+++
Sbjct: 462 EKPYECNQC------------GKSFIQSYKLIAHQRIHTGEKPYECNQCGKSFS--QSYK 507

Query: 301 LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPS 360
           L    +    ++  E  Q G +     S   +L    +        E  +C  S   +  
Sbjct: 508 LVAHQRTHTGEKPFECNQCGKS----FSWSSQLVAHQRTHTGEKPYECSECGKSFNRSSH 563

Query: 361 VDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTC 420
           +    ++ +  EKP  C++CGK+F   + LV+H R H                G +P  C
Sbjct: 564 LVMHQRIHTG-EKPYECNQCGKSFSQSYVLVVHQRTH---------------TGEKPYEC 607

Query: 421 SPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFF 480
           S                + G        L +     +   G K        EC+ CGK F
Sbjct: 608 S----------------QCGKSFRQSSCLTQH---QRTHTGEK------PFECNQCGKTF 642

Query: 481 RSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
             +  L +H RTHTGEKP+ C  C  A      L  H   H +EK
Sbjct: 643 SLSARLIVHQRTHTGEKPFTCIQCGKAFINSYKLIRHQATHTEEK 687



 Score = 96.7 bits (239), Expect = 1e-19
 Identities = 93/381 (24%), Positives = 143/381 (37%), Gaps = 65/381 (17%)

Query: 146 HMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG-KSGARSKLQQGLESSPATINEVVQ 204
           +MR + +   + CN CG+ F     L  H RTH G K    S+  +    S   ++   +
Sbjct: 343 NMRNNSEEKPFECNQCGKSFSWSSHLVAHQRTHTGEKPYECSECGKSFSRSSHLVSH-QR 401

Query: 205 VHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSRED 264
            H  E    PY+ C  CG  F     L+ H++ HT +  +  +               + 
Sbjct: 402 THTGE---KPYR-CNQCGKSFSQSYVLVVHQRTHTGEKPYECNQC------------GKS 445

Query: 265 FLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDN 324
           F Q + L       TG+KP  C      F   Q+++L    ++   ++  E  Q G +  
Sbjct: 446 FRQSYKLIAHQRTHTGEKPYECNQCGKSF--IQSYKLIAHQRIHTGEKPYECNQCGKS-- 501

Query: 325 DDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAF 384
              S   +L    +        E  +C  S   +  + A  +  +  EKP  CSECGK+F
Sbjct: 502 --FSQSYKLVAHQRTHTGEKPFECNQCGKSFSWSSQLVAHQRTHTG-EKPYECSECGKSF 558

Query: 385 RTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDG 444
                LV+H R+H                G +P  C                    ++ G
Sbjct: 559 NRSSHLVMHQRIH---------------TGEKPYEC--------------------NQCG 583

Query: 445 SEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFC 504
                   + + +    G+  +     ECS CGK FR +  L  H RTHTGEKP++C  C
Sbjct: 584 KSFSQSYVLVVHQRTHTGEKPY-----ECSQCGKSFRQSSCLTQHQRTHTGEKPFECNQC 638

Query: 505 EYAAAQKTSLRYHLERHHKEK 525
               +    L  H   H  EK
Sbjct: 639 GKTFSLSARLIVHQRTHTGEK 659



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 101/443 (22%), Positives = 157/443 (35%), Gaps = 108/443 (24%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTE---PP 118
           P +C  C ++F+ S  L  H       +P  C            S   KS  R+      
Sbjct: 352 PFECNQCGKSFSWSSHLVAHQRTHTGEKPYEC------------SECGKSFSRSSHLVSH 399

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           +  +  E  + C  CG++F  ++ + +H RTH     Y CN CG+ F++ + L  H RTH
Sbjct: 400 QRTHTGEKPYRCNQCGKSFSQSYVLVVHQRTHTGEKPYECNQCGKSFRQSYKLIAHQRTH 459

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+                                PY+ C  CG  F     LI H+++H
Sbjct: 460 TGE-------------------------------KPYE-CNQCGKSFIQSYKLIAHQRIH 487

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
           T +  +  +               + F Q + L       TG+KP  C      F+   +
Sbjct: 488 TGEKPYECNQC------------GKSFSQSYKLVAHQRTHTGEKPFECNQCGKSFS--WS 533

Query: 299 WQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA 358
            QL    +    ++  E  + G + N  S     L    +        E  +C  S  ++
Sbjct: 534 SQLVAHQRTHTGEKPYECSECGKSFNRSS----HLVMHQRIHTGEKPYECNQCGKSFSQS 589

Query: 359 PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPG 418
             +    +  +  EKP  CS+CGK+FR    L  H R H                G +P 
Sbjct: 590 YVLVVHQRTHTG-EKPYECSQCGKSFRQSSCLTQHQRTH---------------TGEKPF 633

Query: 419 TCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGK 478
            C                    ++ G    L   + + +    G+ K  T    C  CGK
Sbjct: 634 EC--------------------NQCGKTFSLSARLIVHQRTHTGE-KPFT----CIQCGK 668

Query: 479 FFRSNYYLNIHLRTHTGEKPYKC 501
            F ++Y L  H  THT EK Y+C
Sbjct: 669 AFINSYKLIRHQATHTEEKLYEC 691



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 55/229 (24%), Positives = 84/229 (36%), Gaps = 29/229 (12%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C ++F  S  L  H       +P  C          Y   +   ++ T   
Sbjct: 433 GEKPYECNQCGKSFRQSYKLIAHQRTHTGEKPYECNQCGKSFIQSY-KLIAHQRIHTG-- 489

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
                 E  + C  CG++F  ++ +  H RTH     + CN CG+ F     L  H RTH
Sbjct: 490 ------EKPYECNQCGKSFSQSYKLVAHQRTHTGEKPFECNQCGKSFSWSSQLVAHQRTH 543

Query: 179 NGKSGAR-SKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKV 237
            G+     S+  +    S   +    ++H  E    PY+ C  CG  F     L+ H++ 
Sbjct: 544 TGEKPYECSECGKSFNRSSHLVMHQ-RIHTGEK---PYE-CNQCGKSFSQSYVLVVHQRT 598

Query: 238 HTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRC 286
           HT +  +  S               + F Q   L       TG+KP  C
Sbjct: 599 HTGEKPYECSQC------------GKSFRQSSCLTQHQRTHTGEKPFEC 635



 Score = 35.4 bits (80), Expect = 0.28
 Identities = 25/99 (25%), Positives = 38/99 (38%), Gaps = 7/99 (7%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
           G  P +C  C ++F  S  L +H   Q   T  +P     E            R    + 
Sbjct: 601 GEKPYECSQCGKSFRQSSCLTQH---QRTHTGEKP----FECNQCGKTFSLSARLIVHQR 653

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
            +  E  F+C  CG+ F  ++ +  H  TH +   Y CN
Sbjct: 654 THTGEKPFTCIQCGKAFINSYKLIRHQATHTEEKLYECN 692


>gi|55742736 zinc finger protein 700 [Homo sapiens]
          Length = 742

 Score =  114 bits (286), Expect = 4e-25
 Identities = 121/518 (23%), Positives = 186/518 (35%), Gaps = 85/518 (16%)

Query: 31  PMEMEDALSMKGTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--- 87
           P + +   + K     P   TQE++     G  P  C  C +TF     + +H++M    
Sbjct: 163 PYKCQQPKNKKAFRYRPSIRTQERDHT---GEKPYACKVCGKTFIFHSSIRRHMVMHSGD 219

Query: 88  --HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNC------------------KENE 127
             ++   C  A        +   +++    +P + K C                   E  
Sbjct: 220 GTYKCKFCGKAFHSFSLYLIH--ERTHTGEKPYECKQCGKSFTYSATLQIHERTHTGEKP 277

Query: 128 FSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSK 187
           + C  C + F  +     H R+H     Y C  CG+ F     L+ H RTH+GK     K
Sbjct: 278 YECSKCDKAFHSSSSYHRHERSHMGEKPYQCKECGKAFAYTSSLRRHERTHSGKKPYECK 337

Query: 188 LQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTS 247
                 S   +    +++++ E    PYK C +CG  F + +S   H K HT +  +   
Sbjct: 338 QYGEGLSYLISFQTHIRMNSGE---RPYK-CKICGKGFYSAKSFQTHEKTHTGEKRYKCK 393

Query: 248 SAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKV 307
                           +    F    + H  TG+KP  C      F +  A QL   G  
Sbjct: 394 QC----------GKAFNLSSSFRYHERIH--TGEKPYECKQCGKAFRS--ASQLRVHGGT 439

Query: 308 AICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKL 367
              ++  E  + G      +S  +  G T+ G                            
Sbjct: 440 HTGEKPYECKECGKAFR-STSHLRVHGRTHTG---------------------------- 470

Query: 368 PSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAP 427
               EKP  C ECGKAFR    L +H R  K  R    E P       + G  S      
Sbjct: 471 ----EKPYECKECGKAFRYVKHLQIHERTEKHIRMPSGERP-YKCSICEKGFYSAKSFQT 525

Query: 428 LDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLN 487
            ++    ++    ++ G        +   +    G+  +     EC  CGK FRS  +L 
Sbjct: 526 HEKTHTGEKPYECNQCGKAFRCCNSLRYHERTHTGEKPY-----ECKQCGKAFRSASHLR 580

Query: 488 IHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           +H RTHTGEKPY+C+ C  A +  ++LR H   H  EK
Sbjct: 581 MHERTHTGEKPYECKQCGKAFSCASNLRKHGRTHTGEK 618



 Score =  102 bits (253), Expect = 2e-21
 Identities = 115/497 (23%), Positives = 167/497 (33%), Gaps = 100/497 (20%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
           G  P  C  C + F ++  L +H   +   +  +P   +   E LS L   Q        
Sbjct: 302 GEKPYQCKECGKAFAYTSSLRRH---ERTHSGKKPYECKQYGEGLSYLISFQTHIR---- 354

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
            N  E  + C++CG+ F  A   + H +TH     Y C  CG+ F      + H R H G
Sbjct: 355 MNSGERPYKCKICGKGFYSAKSFQTHEKTHTGEKRYKCKQCGKAFNLSSSFRYHERIHTG 414

Query: 181 KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
           +     K       S + +      H  E    PY+ C  CG  F +   L  H + HT 
Sbjct: 415 EKPYECKQCGKAFRSASQLRVHGGTHTGEK---PYE-CKECGKAFRSTSHLRVHGRTHTG 470

Query: 241 KTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKS-HPETGKKPVRCIPQLDPFTTFQAW 299
           +  +       +  + G        LQ+     K     +G++P +C             
Sbjct: 471 EKPY-------ECKECGKAFRYVKHLQIHERTEKHIRMPSGERPYKC------------- 510

Query: 300 QLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAP 359
                   +IC++   S +   T     + EK       G            + +H    
Sbjct: 511 --------SICEKGFYSAKSFQTHEKTHTGEKPYECNQCGKAFRCCNSLRYHERTH---- 558

Query: 360 SVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGT 419
                     + EKP  C +CGKAFR+   L +H R H                G +P  
Sbjct: 559 ----------TGEKPYECKQCGKAFRSASHLRMHERTHT---------------GEKPYE 593

Query: 420 CSP-----DLAAPLDENGAVDRGEGGSE---------DGSEDGLPEGIHLDKNDDGGKI- 464
           C         A+ L ++G    GE   E           S   + E  H  +     K  
Sbjct: 594 CKQCGKAFSCASNLRKHGRTHTGEKPYECKQCGKAFRSASNLQMHERTHTGEKPYECKEC 653

Query: 465 ---------------KHLTSSR-ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAA 508
                          KH      EC +CG  F S   L IH RTH GEK Y+C+ C  A 
Sbjct: 654 EKAFCKFSSFQIHERKHRGEKPYECKHCGNGFTSAKILQIHARTHIGEKHYECKECGKAF 713

Query: 509 AQKTSLRYHLERHHKEK 525
              +SL  H   H  EK
Sbjct: 714 NYFSSLHIHARTHMGEK 730



 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 77/324 (23%), Positives = 118/324 (36%), Gaps = 24/324 (7%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
           G  P +C  C + F  +  L  H          E         Y+  L   + RTE    
Sbjct: 442 GEKPYECKECGKAFRSTSHLRVHGRTHTGEKPYECKECGKAFRYVKHLQIHE-RTEKHIR 500

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
               E  + C +C + F  A   + H +TH     Y CN CG+ F+    L+ H RTH G
Sbjct: 501 MPSGERPYKCSICEKGFYSAKSFQTHEKTHTGEKPYECNQCGKAFRCCNSLRYHERTHTG 560

Query: 181 KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
           +     K       S + +    + H  E    PY+ C  CG  F    +L +H + HT 
Sbjct: 561 EKPYECKQCGKAFRSASHLRMHERTHTGEK---PYE-CKQCGKAFSCASNLRKHGRTHTG 616

Query: 241 KTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQ 300
           +  +       +  Q G     + F    NL+      TG+KP  C      F  F ++Q
Sbjct: 617 EKPY-------ECKQCG-----KAFRSASNLQMHERTHTGEKPYECKECEKAFCKFSSFQ 664

Query: 301 LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPS 360
           +  +      +   E   E     +  +S K L    +        E ++C  +     S
Sbjct: 665 IHER------KHRGEKPYECKHCGNGFTSAKILQIHARTHIGEKHYECKECGKAFNYFSS 718

Query: 361 VDADPKLPSSKEKPTHCSECGKAF 384
           +    +     EKP  C +CGKAF
Sbjct: 719 LHIHARTHMG-EKPYECKDCGKAF 741



 Score = 54.3 bits (129), Expect = 6e-07
 Identities = 41/150 (27%), Positives = 59/150 (39%), Gaps = 41/150 (27%)

Query: 377 CSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDR 436
           C  CGKAF ++   ++H R H                G +P  C                
Sbjct: 224 CKFCGKAFHSFSLYLIHERTHT---------------GEKPYECK--------------- 253

Query: 437 GEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGE 496
                + G        + + +    G+  +     ECS C K F S+   + H R+H GE
Sbjct: 254 -----QCGKSFTYSATLQIHERTHTGEKPY-----ECSKCDKAFHSSSSYHRHERSHMGE 303

Query: 497 KPYKCEFCEYAAAQKTSLRYHLERHHKEKQ 526
           KPY+C+ C  A A  +SLR H ER H  K+
Sbjct: 304 KPYQCKECGKAFAYTSSLRRH-ERTHSGKK 332



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 40/164 (24%), Positives = 58/164 (35%), Gaps = 30/164 (18%)

Query: 372 EKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDEN 431
           EKP  C +CGK+F     L +H R H                G +P  CS    A    +
Sbjct: 247 EKPYECKQCGKSFTYSATLQIHERTHT---------------GEKPYECSKCDKA-FHSS 290

Query: 432 GAVDRGEGG---------SEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRS 482
            +  R E            E G        +   +    GK  +     EC   G+    
Sbjct: 291 SSYHRHERSHMGEKPYQCKECGKAFAYTSSLRRHERTHSGKKPY-----ECKQYGEGLSY 345

Query: 483 NYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEKQ 526
                 H+R ++GE+PYKC+ C        S + H + H  EK+
Sbjct: 346 LISFQTHIRMNSGERPYKCKICGKGFYSAKSFQTHEKTHTGEKR 389


>gi|169165837 PREDICTED: zinc finger protein 852 [Homo sapiens]
          Length = 496

 Score =  113 bits (283), Expect = 8e-25
 Identities = 114/454 (25%), Positives = 169/454 (37%), Gaps = 124/454 (27%)

Query: 99  RVEAEYLSPLDKS-------------QVRTEPPKEKNCKENE--------FSCEVCGQTF 137
           R+E+++L  +D+              +V   PP   +  E+E        + C+ CG+ F
Sbjct: 110 RLESDFLEIIDEDKKKSTKDRYEEYKEVEEHPPLSSSPVEHEGVLKGQKSYRCDECGKAF 169

Query: 138 RVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGAR-SKLQQGLESSP 196
             +  +  H R H     Y CN CG+ F++   L  H+RTH G+     S+  +    S 
Sbjct: 170 YWSSHLIGHRRIHTGEKPYECNECGKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHS- 228

Query: 197 ATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQG 256
              + ++Q     +   PYK C  C   F     L +H++ HT +  +       +  + 
Sbjct: 229 ---SHLIQHQRLHNGEKPYK-CNECAKAFNQSSKLFDHQRTHTGEKPY-------ECKEC 277

Query: 257 GMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKES 316
           G   SR       NL       TGKKP +C          +  +     +  I  +   +
Sbjct: 278 GAAFSRSK-----NLVRHQFLHTGKKPYKCN---------ECGRAFCSNRNLIDHQRTHT 323

Query: 317 GQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTH 376
           G++    N+                 G +  + KC   H              + EKP  
Sbjct: 324 GEKPYKCNE----------------CGKAFSRSKCLIRHQSL----------HTGEKPYK 357

Query: 377 CSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDR 436
           CSECGKAF    QLV H R+H                G +P  CS               
Sbjct: 358 CSECGKAFNQISQLVEHERIHT---------------GEKPFKCS--------------- 387

Query: 437 GEGGSEDGSEDGLPEGIHLDKNDDGGKIKHL---TSSR--ECSYCGKFFRSNYYLNIHLR 491
                E G   GL + +          I+H    TS +  +C+ CGK F  N YL IH R
Sbjct: 388 -----ECGKAFGLSKCL----------IRHQRLHTSEKPYKCNECGKSFNQNSYLIIHQR 432

Query: 492 THTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
            HTGEKPY+C  C    +  +SL  H   H  EK
Sbjct: 433 IHTGEKPYECNECGKVFSYNSSLMVHQRTHTGEK 466



 Score =  101 bits (251), Expect = 4e-21
 Identities = 82/376 (21%), Positives = 146/376 (38%), Gaps = 69/376 (18%)

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + C  CG+TFR    + +H+RTH     Y C+ CG+ ++    L  H R HNG+   
Sbjct: 185 EKPYECNECGKTFRQTSQLIVHLRTHTGEKPYECSECGKAYRHSSHLIQHQRLHNGEKPY 244

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           +        +  + + +  + H  E    PY+ C  CG  F   ++L+ H+ +HT K  +
Sbjct: 245 KCNECAKAFNQSSKLFDHQRTHTGE---KPYE-CKECGAAFSRSKNLVRHQFLHTGKKPY 300

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATK 304
             +                 F    NL       TG+KP +C          +  +  ++
Sbjct: 301 KCNEC------------GRAFCSNRNLIDHQRTHTGEKPYKC---------NECGKAFSR 339

Query: 305 GKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKH---SHGEAPSV 361
            K  I  +   +G++    ++   +  ++ +  +       ++  KC     + G +  +
Sbjct: 340 SKCLIRHQSLHTGEKPYKCSECGKAFNQISQLVEHERIHTGEKPFKCSECGKAFGLSKCL 399

Query: 362 DADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCS 421
               +L +S EKP  C+ECGK+F     L++H R+H                G +P  C 
Sbjct: 400 IRHQRLHTS-EKPYKCNECGKSFNQNSYLIIHQRIH---------------TGEKPYEC- 442

Query: 422 PDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFR 481
                              +E G        + + +    G+  +     +C+ CGK F 
Sbjct: 443 -------------------NECGKVFSYNSSLMVHQRTHTGEKPY-----KCNSCGKAFS 478

Query: 482 SNYYLNIHLRTHTGEK 497
            +  L +H R HTGEK
Sbjct: 479 DSSQLTVHQRVHTGEK 494



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 15/181 (8%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+ S+ L +H  +    +P  C     +   +    ++  ++ T   
Sbjct: 324 GEKPYKCNECGKAFSRSKCLIRHQSLHTGEKPYKCSECG-KAFNQISQLVEHERIHTG-- 380

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
                 E  F C  CG+ F ++  +  H R H     Y CN CG+ F +  +L  H R H
Sbjct: 381 ------EKPFKCSECGKAFGLSKCLIRHQRLHTSEKPYKCNECGKSFNQNSYLIIHQRIH 434

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+          + S  +++    + H  E    PYK C  CG  F +   L  H++VH
Sbjct: 435 TGEKPYECNECGKVFSYNSSLMVHQRTHTGEK---PYK-CNSCGKAFSDSSQLTVHQRVH 490

Query: 239 T 239
           T
Sbjct: 491 T 491



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 33/124 (26%), Positives = 49/124 (39%), Gaps = 13/124 (10%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRV-EAEYLSPLDKSQVRTEP 117
           G  P  C  C + F  S+ L +H  +    +P  C        +  YL  +   ++ T  
Sbjct: 380 GEKPFKCSECGKAFGLSKCLIRHQRLHTSEKPYKCNECGKSFNQNSYL--IIHQRIHTG- 436

Query: 118 PKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRT 177
                  E  + C  CG+ F     + +H RTH     Y CN CG+ F +   L  H R 
Sbjct: 437 -------EKPYECNECGKVFSYNSSLMVHQRTHTGEKPYKCNSCGKAFSDSSQLTVHQRV 489

Query: 178 HNGK 181
           H G+
Sbjct: 490 HTGE 493


>gi|38708324 zinc finger protein 93 [Homo sapiens]
          Length = 620

 Score =  113 bits (283), Expect = 8e-25
 Identities = 117/472 (24%), Positives = 177/472 (37%), Gaps = 84/472 (17%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F  S  L+KH ++    +P  CE        E     ++S   T+  
Sbjct: 225 GEKPYKCDKCDKAFIASSTLSKHEIIHTGKKPYKCE--------ECGKAFNQSSTLTKH- 275

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K+ +  E  + CE CG+ F  +  +  H + H     Y C  CG+ FK    L  H R H
Sbjct: 276 KKIHTGEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCEECGKAFKYSRILTTHKRIH 335

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+   +         + +T++    +H  +     YK C  CG  F     L  H++VH
Sbjct: 336 TGEKPYKCNKCGKAFIASSTLSRHEFIHMGK---KHYK-CEECGKAFIWSSVLTRHKRVH 391

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPF---TT 295
           T +  +               SS +          +SH  TG+KP +C      F   +T
Sbjct: 392 TGEKPYKCEECGKAFKYSSTLSSHK----------RSH--TGEKPYKCEECGKAFVASST 439

Query: 296 FQAWQLATKGKVAI-CQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHS 354
               ++   GK    C+E       G   N  SS  K      K        + E+C  +
Sbjct: 440 LSKHEIIHTGKKPYKCEEC------GKAFNQSSSLTKH----KKIHTGEKPYKCEECGKA 489

Query: 355 HGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDG 414
             ++ S+    K+ +  EKP  C ECGKAF     L+ H ++H +++             
Sbjct: 490 FNQSSSLTKHKKIHTG-EKPYKCEECGKAFNQSSTLIKHKKIHTREK------------- 535

Query: 415 RQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHL-TSSREC 473
             P  C        +E G                  +  HL  +    KI H       C
Sbjct: 536 --PYKC--------EECG------------------KAFHLSTHLTTHKILHTGEKPYRC 567

Query: 474 SYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
             CGK F  +  L+ H + H+GEKPY+C+ C  A    +SL  H   H  EK
Sbjct: 568 RECGKAFNHSATLSSHKKIHSGEKPYECDKCGKAFISPSSLSRHEIIHTGEK 619



 Score =  101 bits (251), Expect = 4e-21
 Identities = 102/423 (24%), Positives = 158/423 (37%), Gaps = 95/423 (22%)

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K+ +  E  + CE CG+ F+ +  +  H R H     Y C+ C + F     L  H   H
Sbjct: 192 KKIHTGEKPYICEECGKAFKYSSALNTHKRIHTGEKPYKCDKCDKAFIASSTLSKHEIIH 251

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            GK   + +      +  +T+ +  ++H  E    PYK C  CG  F    +L +H+K+H
Sbjct: 252 TGKKPYKCEECGKAFNQSSTLTKHKKIHTGE---KPYK-CEECGKAFNQSSTLTKHKKIH 307

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
           T +  +                    + ++     + H  TG+KP +C            
Sbjct: 308 TGEKPYVCEEC----------GKAFKYSRILTTHKRIH--TGEKPYKC------------ 343

Query: 299 WQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA 358
                 GK  I                           ++     + ++  KC+   G+A
Sbjct: 344 ---NKCGKAFIASST----------------------LSRHEFIHMGKKHYKCEEC-GKA 377

Query: 359 ---PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDR--------RAGAES 407
               SV    K   + EKP  C ECGKAF+    L  H R H  ++        +A   S
Sbjct: 378 FIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFVAS 437

Query: 408 PTMSV-----DGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGG 462
            T+S       G++P  C              + G+  ++  S         L K+    
Sbjct: 438 STLSKHEIIHTGKKPYKCE-------------ECGKAFNQSSS---------LTKHK--- 472

Query: 463 KIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHH 522
           KI       +C  CGK F  +  L  H + HTGEKPYKCE C  A  Q ++L  H + H 
Sbjct: 473 KIHTGEKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIKHKKIHT 532

Query: 523 KEK 525
           +EK
Sbjct: 533 REK 535



 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 104/431 (24%), Positives = 165/431 (38%), Gaps = 59/431 (13%)

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
           ++ ++  F C  CG+ F     +  H + H     Y C  CG+ FK    L  H R H G
Sbjct: 166 RHTEKKPFKCIECGKAFNQFSTLITHKKIHTGEKPYICEECGKAFKYSSALNTHKRIHTG 225

Query: 181 KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
           +   +         + +T+++   +H  +    PYK C  CG  F    +L +H+K+HT 
Sbjct: 226 EKPYKCDKCDKAFIASSTLSKHEIIHTGKK---PYK-CEECGKAFNQSSTLTKHKKIHT- 280

Query: 241 KTAFGTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDPFTTF 296
                          G  P   E+  + FN    L       TG+KP  C          
Sbjct: 281 ---------------GEKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYVCE--------- 316

Query: 297 QAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHG 356
           +  +     ++    +   +G++    N    +       ++     + ++  KC+   G
Sbjct: 317 ECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFIHMGKKHYKCEEC-G 375

Query: 357 EA---PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDR--------RAGA 405
           +A    SV    K   + EKP  C ECGKAF+    L  H R H  ++        +A  
Sbjct: 376 KAFIWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYKCEECGKAFV 435

Query: 406 ESPTMSVD-----GRQPGTCSP-----DLAAPLDENGAVDRGEGGSE-DGSEDGLPEGIH 454
            S T+S       G++P  C       + ++ L ++  +  GE   + +       +   
Sbjct: 436 ASSTLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCEECGKAFNQSSS 495

Query: 455 LDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSL 514
           L K+    KI       +C  CGK F  +  L  H + HT EKPYKCE C  A    T L
Sbjct: 496 LTKHK---KIHTGEKPYKCEECGKAFNQSSTLIKHKKIHTREKPYKCEECGKAFHLSTHL 552

Query: 515 RYHLERHHKEK 525
             H   H  EK
Sbjct: 553 TTHKILHTGEK 563



 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 92/370 (24%), Positives = 139/370 (37%), Gaps = 38/370 (10%)

Query: 50  ATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSP 107
           +T  K+ I   G  P  C  C + F  S  L KH  +    +P  CE        E    
Sbjct: 242 STLSKHEIIHTGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYKCE--------ECGKA 293

Query: 108 LDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKE 167
            ++S   T+  K+ +  E  + CE CG+ F+ +  +  H R H     Y CN CG+ F  
Sbjct: 294 FNQSSTLTKH-KKIHTGEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIA 352

Query: 168 PWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPN 227
              L  H   H GK   + +         + +    +VH  E    PYK C  CG  F  
Sbjct: 353 SSTLSRHEFIHMGKKHYKCEECGKAFIWSSVLTRHKRVHTGEK---PYK-CEECGKAFKY 408

Query: 228 KESLIEHRKVHTKK------------TAFGTSSAQTDSPQGGMPSSREDFLQLFN----L 271
             +L  H++ HT +             A  T S       G  P   E+  + FN    L
Sbjct: 409 SSTLSSHKRSHTGEKPYKCEECGKAFVASSTLSKHEIIHTGKKPYKCEECGKAFNQSSSL 468

Query: 272 RPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEK 331
                  TG+KP +C      F   Q+  L    K+   ++  +  + G   N  S+  K
Sbjct: 469 TKHKKIHTGEKPYKCEECGKAFN--QSSSLTKHKKIHTGEKPYKCEECGKAFNQSSTLIK 526

Query: 332 ELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLV 391
                 K        + E+C  +   +  +    K+  + EKP  C ECGKAF     L 
Sbjct: 527 H----KKIHTREKPYKCEECGKAFHLSTHLTTH-KILHTGEKPYRCRECGKAFNHSATLS 581

Query: 392 LHSRVHKKDR 401
            H ++H  ++
Sbjct: 582 SHKKIHSGEK 591



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 52/192 (27%), Positives = 79/192 (41%), Gaps = 15/192 (7%)

Query: 50  ATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSP 107
           +T  K+ I   G  P  C  C + F  S  L KH  +    +P  CE        E    
Sbjct: 438 STLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKKIHTGEKPYKCE--------ECGKA 489

Query: 108 LDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKE 167
            ++S   T+  K+ +  E  + CE CG+ F  +  +  H + H     Y C  CG+ F  
Sbjct: 490 FNQSSSLTKH-KKIHTGEKPYKCEECGKAFNQSSTLIKHKKIHTREKPYKCEECGKAFHL 548

Query: 168 PWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPN 227
              L  H   H G+   R +      +  AT++   ++H+ E    PY+ C  CG  F +
Sbjct: 549 STHLTTHKILHTGEKPYRCRECGKAFNHSATLSSHKKIHSGEK---PYE-CDKCGKAFIS 604

Query: 228 KESLIEHRKVHT 239
             SL  H  +HT
Sbjct: 605 PSSLSRHEIIHT 616


>gi|222831664 zinc finger protein 184 [Homo sapiens]
          Length = 751

 Score =  113 bits (282), Expect = 1e-24
 Identities = 126/449 (28%), Positives = 186/449 (41%), Gaps = 68/449 (15%)

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           KEK+CK NE     CG+ F     +  H RTH     Y CN C + F     L NH R H
Sbjct: 218 KEKSCKCNE-----CGKAFSYCSALIRHQRTHTGEKPYKCNECEKAFSRSENLINHQRIH 272

Query: 179 NG-KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKV 237
            G K     +  +G    P ++ +  ++H  E    PYK C  CG  F  +  L++H+++
Sbjct: 273 TGDKPYKCDQCGKGFIEGP-SLTQHQRIHTGE---KPYK-CDECGKAFSQRTHLVQHQRI 327

Query: 238 HTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFT--- 294
           HT +  +      T +  G   S R  F++      K H  TG+KP +C      FT   
Sbjct: 328 HTGEKPY------TCNECGKAFSQRGHFME----HQKIH--TGEKPFKCDECDKTFTRST 375

Query: 295 -TFQAWQLATKGKVAICQEVKESGQEGST---DNDDSSSEK--ELGETNK--GSCAGLSQ 346
              Q  ++ T  K   C E  ++    ST    +   + EK  E  E  K     + L+Q
Sbjct: 376 HLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQ 435

Query: 347 EKE-----------KCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSR 395
            ++           +C  S     S+    K+ +  EKP  C+ECGKAF     L  H R
Sbjct: 436 HQKTHTGEKPYDCAECGKSFSYWSSLAQHLKIHTG-EKPYKCNECGKAFSYCSSLTQHRR 494

Query: 396 VHKKDR-----RAGAESPTMSVDGRQPGTCSPDLAAPLDENG-AVDRGEGGSEDGSEDGL 449
           +H +++       G     +S   +   T + + A    E G A  R    S     + +
Sbjct: 495 IHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKAYECKECGKAFIR---SSSLAKHERI 551

Query: 450 PEGIHLDKNDDGGK--------IKHL---TSSR--ECSYCGKFFRSNYYLNIHLRTHTGE 496
             G    +  + GK        I+H    T  R  +C+ CG+ F  N +L  H R HTG 
Sbjct: 552 HTGEKPYQCHECGKTFSYGSSLIQHRKIHTGERPYKCNECGRAFNQNIHLTQHKRIHTGA 611

Query: 497 KPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           KPY+C  C  A    +SL  H + H +EK
Sbjct: 612 KPYECAECGKAFRHCSSLAQHQKTHTEEK 640



 Score =  104 bits (260), Expect = 4e-22
 Identities = 117/509 (22%), Positives = 187/509 (36%), Gaps = 74/509 (14%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLR-VEAEYLSPLDKSQVRTEP 117
           G  P  C  C + F+ SE+L  H  +    +P  C+      +E   L+   +     +P
Sbjct: 246 GEKPYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQRIHTGEKP 305

Query: 118 PKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
            K   C                   E  ++C  CG+ F        H + H     + C+
Sbjct: 306 YKCDECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCD 365

Query: 160 MCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICM 219
            C + F     L  H + H G+   +        + P+T      +H  E    PY+ C 
Sbjct: 366 ECDKTFTRSTHLTQHQKIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEK---PYE-CN 421

Query: 220 VCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPET 279
            CG  F    +L +H+K HT +  +       D  + G     + F    +L       T
Sbjct: 422 ECGKAFSQHSNLTQHQKTHTGEKPY-------DCAECG-----KSFSYWSSLAQHLKIHT 469

Query: 280 GKKPVRCIPQLDPFT----TFQAWQLATKGKVAICQEVKES-------GQEGSTDNDDSS 328
           G+KP +C      F+      Q  ++ T+ K   C E  ++        Q   T   + +
Sbjct: 470 GEKPYKCNECGKAFSYCSSLTQHRRIHTREKPFECSECGKAFSYLSNLNQHQKTHTQEKA 529

Query: 329 SE-KELGETNKGSCAGLSQEK----------EKCKHSHGEAPSVDADPKLPSSKEKPTHC 377
            E KE G+    S +    E+           +C  +     S+    K+ +  E+P  C
Sbjct: 530 YECKECGKAFIRSSSLAKHERIHTGEKPYQCHECGKTFSYGSSLIQHRKIHTG-ERPYKC 588

Query: 378 SECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRG 437
           +ECG+AF     L  H R+H      GA+    +  G+    CS      L ++      
Sbjct: 589 NECGRAFNQNIHLTQHKRIH-----TGAKPYECAECGKAFRHCSS-----LAQHQKTHTE 638

Query: 438 EGGSE-DGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGE 496
           E   + +  E    +  HL ++    +I       +C+ C K F  + +L  H  THTGE
Sbjct: 639 EKPYQCNKCEKTFSQSSHLTQHQ---RIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTGE 695

Query: 497 KPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           KPY C  C    +Q T L  H   H  EK
Sbjct: 696 KPYNCNECRKTFSQSTYLIQHQRIHSGEK 724



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 104/466 (22%), Positives = 169/466 (36%), Gaps = 80/466 (17%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKE 120
           G  P  C  C +TFT S  L +H                                   ++
Sbjct: 358 GEKPFKCDECDKTFTRSTHLTQH-----------------------------------QK 382

Query: 121 KNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
            +  E  + C  CG+ F        H   H     Y CN CG+ F +   L  H +TH G
Sbjct: 383 IHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHTG 442

Query: 181 KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTK 240
           +            S  +++ + +++H  E    PYK C  CG  F    SL +HR++HT+
Sbjct: 443 EKPYDCAECGKSFSYWSSLAQHLKIHTGEK---PYK-CNECGKAFSYCSSLTQHRRIHTR 498

Query: 241 KTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQ 300
           +  F  S               + F  L NL       T +K   C      F   ++  
Sbjct: 499 EKPFECSECG------------KAFSYLSNLNQHQKTHTQEKAYECKECGKAF--IRSSS 544

Query: 301 LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPS 360
           LA   ++   ++  +  + G T +  SS    L +  K        +  +C  +  +   
Sbjct: 545 LAKHERIHTGEKPYQCHECGKTFSYGSS----LIQHRKIHTGERPYKCNECGRAFNQNIH 600

Query: 361 VDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTC 420
           +    ++ +   KP  C+ECGKAFR    L  H + H +++              Q   C
Sbjct: 601 LTQHKRIHTGA-KPYECAECGKAFRHCSSLAQHQKTHTEEKPY------------QCNKC 647

Query: 421 SPDLA--APLDENGAVDRGEGGSEDGSED-GLPEGIHLDK--NDDGGKIKHLTSSRECSY 475
               +  + L ++  +  GE   +    D       HL +  N   G+  +      C+ 
Sbjct: 648 EKTFSQSSHLTQHQRIHTGEKPYKCNECDKAFSRSTHLTEHQNTHTGEKPY-----NCNE 702

Query: 476 CGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERH 521
           C K F  + YL  H R H+GEKP+ C  C  +   +++L  H   H
Sbjct: 703 CRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLH 748



 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 55/188 (29%), Positives = 78/188 (41%), Gaps = 25/188 (13%)

Query: 349 EKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESP 408
           ++C     E PS+    ++ +  EKP  C ECGKAF     LV H R+H           
Sbjct: 281 DQCGKGFIEGPSLTQHQRIHTG-EKPYKCDECGKAFSQRTHLVQHQRIHT---------- 329

Query: 409 TMSVDGRQPGTCSP-----DLAAPLDENGAVDRGEGGSE-DGSEDGLPEGIHLDKNDDGG 462
                G +P TC+             E+  +  GE   + D  +       HL ++    
Sbjct: 330 -----GEKPYTCNECGKAFSQRGHFMEHQKIHTGEKPFKCDECDKTFTRSTHLTQHQ--- 381

Query: 463 KIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHH 522
           KI     + +C+ CGK F        H   HTGEKPY+C  C  A +Q ++L  H + H 
Sbjct: 382 KIHTGEKTYKCNECGKAFNGPSTFIRHHMIHTGEKPYECNECGKAFSQHSNLTQHQKTHT 441

Query: 523 KEKQTDVA 530
            EK  D A
Sbjct: 442 GEKPYDCA 449



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 63/235 (26%), Positives = 96/235 (40%), Gaps = 34/235 (14%)

Query: 297 QAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHG 356
           QA Q     ++ + ++   S ++G  +N       E G++   S   ++QE    + S  
Sbjct: 154 QANQQTLPKEIKVTEKTIPSWEKGPVNN-------EFGKSVNVSSNLVTQEPSPEETSTK 206

Query: 357 EAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQ 416
            +   +++P     KEK   C+ECGKAF     L+ H R H                G +
Sbjct: 207 RSIKQNSNPV---KKEKSCKCNECGKAFSYCSALIRHQRTH---------------TGEK 248

Query: 417 PGTCSP-DLAAPLDEN----GAVDRGEGGSE-DGSEDGLPEGIHLDKNDDGGKIKHLTSS 470
           P  C+  + A    EN      +  G+   + D    G  EG  L ++    +I      
Sbjct: 249 PYKCNECEKAFSRSENLINHQRIHTGDKPYKCDQCGKGFIEGPSLTQHQ---RIHTGEKP 305

Query: 471 RECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
            +C  CGK F    +L  H R HTGEKPY C  C  A +Q+     H + H  EK
Sbjct: 306 YKCDECGKAFSQRTHLVQHQRIHTGEKPYTCNECGKAFSQRGHFMEHQKIHTGEK 360



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 33/119 (27%), Positives = 49/119 (41%), Gaps = 11/119 (9%)

Query: 64  PLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEK 121
           P  C  C +TF+ S  L +H  +    +P  C         E      +S   TE  +  
Sbjct: 641 PYQCNKCEKTFSQSSHLTQHQRIHTGEKPYKCN--------ECDKAFSRSTHLTEH-QNT 691

Query: 122 NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNG 180
           +  E  ++C  C +TF  +  +  H R H     +GCN CG+ F+    L  H R H G
Sbjct: 692 HTGEKPYNCNECRKTFSQSTYLIQHQRIHSGEKPFGCNDCGKSFRYRSALNKHQRLHPG 750


>gi|150170667 zinc finger protein 471 [Homo sapiens]
          Length = 626

 Score =  112 bits (281), Expect = 1e-24
 Identities = 114/468 (24%), Positives = 167/468 (35%), Gaps = 95/468 (20%)

Query: 67  CMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCKEN 126
           C  C +TFTHS  L  H  +                                   +  E 
Sbjct: 208 CNECDKTFTHSSSLTVHFRI-----------------------------------HTGEK 232

Query: 127 EFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARS 186
            ++CE CG+ F+    +  H RTH     + C  C + FK+   L  H R H G+   + 
Sbjct: 233 PYACEECGKAFKQRQHLAQHHRTHTGEKLFECKECRKAFKQSEHLIQHQRIHTGEKPYKC 292

Query: 187 KLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGT 246
           K  +     PA + +  ++H  E    PY+ C  CG  F +  S   H++ HT K  +  
Sbjct: 293 KECRKAFRQPAHLAQHQRIHTGEK---PYE-CKECGKAFSDGSSFARHQRCHTGKRPYEC 348

Query: 247 SSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATK-- 304
                    G        F++ +    +S+  TG+KP  CI     F+      L  +  
Sbjct: 349 IEC------GKAFRYNTSFIRHW----RSY-HTGEKPFNCIDCGKAFSVHIGLILHRRIH 397

Query: 305 -----GKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAP 359
                 K  +C +   SG   +      + EK               E + C        
Sbjct: 398 TGEKPYKCGVCGKTFSSGSSRTVHQRIHTGEKPY-------------ECDICGKDFSHHA 444

Query: 360 SVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGT 419
           S+    ++ S  EKP  C ECGKAFR    LV H R+H                G +P  
Sbjct: 445 SLTQHQRVHSG-EKPYECKECGKAFRQNVHLVSHLRIHT---------------GEKPYE 488

Query: 420 CSP-----DLAAPLDENGAVDRGEGGSED-GSEDGLPEGIHLDKNDDGGKIKHLTSSREC 473
           C        +++ L  +  +  GE   E     +   +  HL ++    K        EC
Sbjct: 489 CKECGKAFRISSQLATHQRIHTGEKPYECIECGNAFKQRSHLAQHQ---KTHTGEKPYEC 545

Query: 474 SYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERH 521
           + CGK F     L  H R HTGEKPYKC  C  A +  +S   H   H
Sbjct: 546 NECGKAFSQTSNLTQHQRIHTGEKPYKCTECGKAFSDSSSCAQHQRLH 593



 Score =  100 bits (249), Expect = 7e-21
 Identities = 105/422 (24%), Positives = 150/422 (35%), Gaps = 110/422 (26%)

Query: 128 FSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSK 187
           F C  C +TF  +  + +H R H     Y C  CG+ FK+    + H+  H+        
Sbjct: 206 FKCNECDKTFTHSSSLTVHFRIHTGEKPYACEECGKAFKQ----RQHLAQHH-------- 253

Query: 188 LQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGTS 247
                           + H  E +      C  C   F   E LI+H+++HT +  +   
Sbjct: 254 ----------------RTHTGEKLFE----CKECRKAFKQSEHLIQHQRIHTGEKPYKCK 293

Query: 248 SAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGKV 307
                         R+ F Q  +L       TG+KP  C                     
Sbjct: 294 EC------------RKAFRQPAHLAQHQRIHTGEKPYEC--------------------- 320

Query: 308 AICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKL 367
                 KE G+  S    D SS       + G       E  +C  +     S     + 
Sbjct: 321 ------KECGKAFS----DGSSFARHQRCHTGK---RPYECIECGKAFRYNTSFIRHWRS 367

Query: 368 PSSKEKPTHCSECGKAFRTYHQLVLHSRVH--KKDRRAGAESPTMSVD-----------G 414
             + EKP +C +CGKAF  +  L+LH R+H  +K  + G    T S             G
Sbjct: 368 YHTGEKPFNCIDCGKAFSVHIGLILHRRIHTGEKPYKCGVCGKTFSSGSSRTVHQRIHTG 427

Query: 415 RQP---GTCSPDLA--APLDENGAVDRGEGGSE-DGSEDGLPEGIHLDKNDDGGKIKHLT 468
            +P     C  D +  A L ++  V  GE   E         + +HL        + HL 
Sbjct: 428 EKPYECDICGKDFSHHASLTQHQRVHSGEKPYECKECGKAFRQNVHL--------VSHLR 479

Query: 469 -----SSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHK 523
                   EC  CGK FR +  L  H R HTGEKPY+C  C  A  Q++ L  H + H  
Sbjct: 480 IHTGEKPYECKECGKAFRISSQLATHQRIHTGEKPYECIECGNAFKQRSHLAQHQKTHTG 539

Query: 524 EK 525
           EK
Sbjct: 540 EK 541



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 79/339 (23%), Positives = 127/339 (37%), Gaps = 33/339 (9%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P +C  C + F+      +H       RP  C      +E       + S +R    
Sbjct: 314 GEKPYECKECGKAFSDGSSFARHQRCHTGKRPYEC------IECGKAFRYNTSFIRHW-- 365

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           +  +  E  F+C  CG+ F V   + +H R H     Y C +CG+ F        H R H
Sbjct: 366 RSYHTGEKPFNCIDCGKAFSVHIGLILHRRIHTGEKPYKCGVCGKTFSSGSSRTVHQRIH 425

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+      +     S  A++ +  +VH+ E    PY+ C  CG  F     L+ H ++H
Sbjct: 426 TGEKPYECDICGKDFSHHASLTQHQRVHSGEK---PYE-CKECGKAFRQNVHLVSHLRIH 481

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
           T +  +                  + F     L       TG+KP  CI   + F   Q 
Sbjct: 482 TGEKPYECKECG------------KAFRISSQLATHQRIHTGEKPYECIECGNAFK--QR 527

Query: 299 WQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA 358
             LA   K    ++  E  + G   +  S+    L +  +        +  +C  +  ++
Sbjct: 528 SHLAQHQKTHTGEKPYECNECGKAFSQTSN----LTQHQRIHTGEKPYKCTECGKAFSDS 583

Query: 359 PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVH 397
            S     +L +  ++P  C ECGKAFR    L+ H R H
Sbjct: 584 SSCAQHQRLHTG-QRPYQCFECGKAFRRKLSLICHQRSH 621



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 51/201 (25%), Positives = 78/201 (38%), Gaps = 27/201 (13%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKH--VLMQHRPTLCEPA--VLRVEAEYLSPLDKSQVRTE 116
           G  P +C  C + F+H   L +H  V    +P  C+      R     +S L +     +
Sbjct: 427 GEKPYECDICGKDFSHHASLTQHQRVHSGEKPYECKECGKAFRQNVHLVSHL-RIHTGEK 485

Query: 117 PPKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGC 158
           P + K C                   E  + C  CG  F+    +  H +TH     Y C
Sbjct: 486 PYECKECGKAFRISSQLATHQRIHTGEKPYECIECGNAFKQRSHLAQHQKTHTGEKPYEC 545

Query: 159 NMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKIC 218
           N CG+ F +   L  H R H G+   +        S  ++  +  ++H  +    PY+ C
Sbjct: 546 NECGKAFSQTSNLTQHQRIHTGEKPYKCTECGKAFSDSSSCAQHQRLHTGQ---RPYQ-C 601

Query: 219 MVCGFLFPNKESLIEHRKVHT 239
             CG  F  K SLI H++ HT
Sbjct: 602 FECGKAFRRKLSLICHQRSHT 622



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 33/142 (23%), Positives = 50/142 (35%), Gaps = 21/142 (14%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLC-EPAVLRVEAEYLSPLDKSQVRTEP 117
           G  P +C  C + F  S  L  H  +    +P  C E      +  +L+   K+    +P
Sbjct: 483 GEKPYECKECGKAFRISSQLATHQRIHTGEKPYECIECGNAFKQRSHLAQHQKTHTGEKP 542

Query: 118 PKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
            +   C                   E  + C  CG+ F  +     H R H     Y C 
Sbjct: 543 YECNECGKAFSQTSNLTQHQRIHTGEKPYKCTECGKAFSDSSSCAQHQRLHTGQRPYQCF 602

Query: 160 MCGRRFKEPWFLKNHMRTHNGK 181
            CG+ F+    L  H R+H G+
Sbjct: 603 ECGKAFRRKLSLICHQRSHTGE 624


>gi|6005976 zinc finger protein 208 [Homo sapiens]
          Length = 1167

 Score =  112 bits (281), Expect = 1e-24
 Identities = 126/494 (25%), Positives = 188/494 (38%), Gaps = 63/494 (12%)

Query: 42   GTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLR 99
            G A   F    +  VI   G  P  C  C + F  S +L +H  +    +P  CE     
Sbjct: 571  GKAFSKFSILTKHKVIHT-GEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKS 629

Query: 100  VEAEYLSPLDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCN 159
                  S L K +V        +  E  + CE CG+ ++ +  +  H + H     Y C 
Sbjct: 630  FST--FSVLTKHKVI-------HTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCE 680

Query: 160  MCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICM 219
             CG+ F     L  H R H  +   + +      S  +T+     +HA E    PYK C 
Sbjct: 681  ECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHAGEK---PYK-CK 736

Query: 220  VCGFLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPET 279
             CG  F     L +H+ +HT +  +     +        PS+        +   K H  T
Sbjct: 737  ECGKAFSKFSILTKHKVIHTGEKPY---KCEECGKAYKWPST-------LSYHKKIH--T 784

Query: 280  GKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKG 339
            G+KP +C      F+ F    + TK       EV  +G++     +   +   L   +K 
Sbjct: 785  GEKPYKCEECGKGFSMFS---ILTK------HEVIHTGEKPYKCEECGKAFSWLSVFSKH 835

Query: 340  SCAGLSQEKEKCKHSHGEAP---SVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRV 396
                  ++  KC+ + G+A    S+    K+  + EKP  C ECGKAF     L+ H ++
Sbjct: 836  KKTHAGEKFYKCE-ACGKAYNTFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKKI 894

Query: 397  HKKDRRAGAESPTMSVDGRQPGTCSPDLAAP--LDENGAVDRGEGG---SEDGSEDGLPE 451
            H  +     E             C    + P  L E+ A   GE      E G     P 
Sbjct: 895  HTGETPYKCEE------------CDKAFSWPSSLTEHKATHAGEKPYKCEECGKAFSWPS 942

Query: 452  GIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQK 511
             +   K    G+  +     +C  CGK F  +  L  H R HTGEKPYKCE C  + +  
Sbjct: 943  RLTEHKATHAGEEPY-----KCEECGKAFNWSSNLMEHKRIHTGEKPYKCEECGKSFSTF 997

Query: 512  TSLRYHLERHHKEK 525
            + L  H   H  EK
Sbjct: 998  SILTKHKVIHTGEK 1011



 Score =  108 bits (269), Expect = 3e-23
 Identities = 141/535 (26%), Positives = 205/535 (38%), Gaps = 89/535 (16%)

Query: 42  GTAVVPFRATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLR 99
           G A   F    +  VI   G     C  C + F  S  L KH ++    +P  CE     
Sbjct: 235 GKAFSKFSILTKHKVIHT-GEKSYKCEECGKAFNQSAILTKHKIIHTGEKPNKCEECGKA 293

Query: 100 V-EAEYLSPLDKSQVRTEPPKEKNCK------------------ENEFSCEVCGQTFRVA 140
             +   L+         +P K K C                   E  + C+ CG+ F   
Sbjct: 294 FSKVSTLTTHKAIHAGEKPYKCKECGKAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKF 353

Query: 141 FDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGAR-SKLQQGLES-SPAT 198
             +  H   H     Y C  CG+ +K P  L  H + H G+   +  +  +G    S  T
Sbjct: 354 SILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEKPYKCEECGKGFSMFSILT 413

Query: 199 INEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF-------GTSSAQT 251
            +EV  +H  E    PYK C  CG  F    +L+EH+K+HT +T +       G S + T
Sbjct: 414 KHEV--IHTGE---KPYK-CEECGKAFNWSSNLMEHKKIHTGETPYKCEECGKGFSWSST 467

Query: 252 DSPQGGM-----PSSREDFLQLFN----LRPKSHPETGKKPVRC------IPQLDPFTTF 296
            S    +     P   E+  + FN    L       TG+KP +C        ++   TT 
Sbjct: 468 LSYHKKIHTVEKPYKCEECGKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTH 527

Query: 297 QAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHG 356
           +A  +    K   C+E  ++  + ST             T+K   AG  ++  KCK   G
Sbjct: 528 KA--IHAGEKPYKCKECGKTFIKVSTLT-----------THKAIHAG--EKPYKCKEC-G 571

Query: 357 EA---PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVD 413
           +A    S+    K+  + EKP  C ECGKAF     L+ H R+H  ++    E       
Sbjct: 572 KAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKRIHTGEKPYKCEE-----C 626

Query: 414 GRQPGTCSPDLAAPLDENGAVDRGEGG---SEDGSEDGLPEGIHLDKNDDGGKIKHLTSS 470
           G+   T S      L ++  +  GE      E G        +   K     KI  +   
Sbjct: 627 GKSFSTFS-----VLTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHK-----KIHTVEKP 676

Query: 471 RECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
            +C  CGK F  +  L  H R HT EKPYKCE C    ++ ++L  H   H  EK
Sbjct: 677 YKCEECGKAFNRSAILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHAGEK 731



 Score =  107 bits (266), Expect = 8e-23
 Identities = 124/495 (25%), Positives = 181/495 (36%), Gaps = 74/495 (14%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+    L KH ++    +P  CE        E     + S    E  
Sbjct: 393 GEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCE--------ECGKAFNWSSNLMEH- 443

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K+ +  E  + CE CG+ F  +  +  H + H     Y C  CG+ F +   L  H R H
Sbjct: 444 KKIHTGETPYKCEECGKGFSWSSTLSYHKKIHTVEKPYKCEECGKAFNQSAILIKHKRIH 503

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+   + +      S  +T+     +HA E    PYK C  CG  F    +L  H+ +H
Sbjct: 504 TGEKPYKCEECGKTFSKVSTLTTHKAIHAGE---KPYK-CKECGKTFIKVSTLTTHKAIH 559

Query: 239 TKK---------TAFGTSSAQTDSP---QGGMPSSREDFLQLF----NLRPKSHPETGKK 282
             +          AF   S  T       G  P   E+  + F    NL       TG+K
Sbjct: 560 AGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKRIHTGEK 619

Query: 283 PVRCIPQLDPFTTFQAWQ----LATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNK 338
           P +C      F+TF        + T  K   C+E  ++ +  ST     S  K++    K
Sbjct: 620 PYKCEECGKSFSTFSVLTKHKVIHTGEKPYKCEECGKAYKWSST----LSYHKKIHTVEK 675

Query: 339 GSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHK 398
                   + E+C  +   + ++    K   + EKP  C ECGK F     L  H  +H 
Sbjct: 676 ------PYKCEECGKAFNRS-AILIKHKRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHA 728

Query: 399 KDRRAGAESPTMSVDGRQPGTCSP-----DLAAPLDENGAVDRGEGG---SEDGSEDGLP 450
                          G +P  C          + L ++  +  GE      E G     P
Sbjct: 729 ---------------GEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWP 773

Query: 451 EGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQ 510
             +   K    G+  +     +C  CGK F     L  H   HTGEKPYKCE C  A + 
Sbjct: 774 STLSYHKKIHTGEKPY-----KCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSW 828

Query: 511 KTSLRYHLERHHKEK 525
            +    H + H  EK
Sbjct: 829 LSVFSKHKKTHAGEK 843



 Score =  106 bits (265), Expect = 1e-22
 Identities = 121/488 (24%), Positives = 180/488 (36%), Gaps = 60/488 (12%)

Query: 61   GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
            G  P  C  C + +  S  L+ H  +    +P  CE        E     ++S +  +  
Sbjct: 645  GEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCE--------ECGKAFNRSAILIKH- 695

Query: 119  KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
            K  +  E  + CE CG+TF     +  H   H     Y C  CG+ F +   L  H   H
Sbjct: 696  KRIHTDEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKAFSKFSILTKHKVIH 755

Query: 179  NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
             G+   + +        P+T++   ++H  E    PYK C  CG  F     L +H  +H
Sbjct: 756  TGEKPYKCEECGKAYKWPSTLSYHKKIHTGEK---PYK-CEECGKGFSMFSILTKHEVIH 811

Query: 239  TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
            T +  +                    +L +F+   K+H   G+K  +C      + TF  
Sbjct: 812  TGEKPYKCEEC----------GKAFSWLSVFSKHKKTH--AGEKFYKCEACGKAYNTFS- 858

Query: 299  WQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA 358
              + TK KV    E     +E     + SS+  E  + + G      +E +K        
Sbjct: 859  --ILTKHKVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGETPYKCEECDKAF----SW 912

Query: 359  PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVD----- 413
            PS   + K   + EKP  C ECGKAF    +L  H   H  +     E    + +     
Sbjct: 913  PSSLTEHKATHAGEKPYKCEECGKAFSWPSRLTEHKATHAGEEPYKCEECGKAFNWSSNL 972

Query: 414  --------GRQPGTC-----SPDLAAPLDENGAVDRGEGG---SEDGSEDGLPEGIHLDK 457
                    G +P  C     S    + L ++  +  GE      E G        +   K
Sbjct: 973  MEHKRIHTGEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHK 1032

Query: 458  NDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYH 517
                 KI  +    +C  CGK F     L  H   HTGEK YKCE C  A    ++LRYH
Sbjct: 1033 -----KIHTVEKPYKCEECGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYH 1087

Query: 518  LERHHKEK 525
             + H  EK
Sbjct: 1088 KKIHTGEK 1095



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 114/469 (24%), Positives = 174/469 (37%), Gaps = 58/469 (12%)

Query: 61   GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
            G  P  C  C + F+    L KH ++    +P  CE         Y  P   S       
Sbjct: 729  GEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEEC----GKAYKWPSTLSY-----H 779

Query: 119  KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
            K+ +  E  + CE CG+ F +   +  H   H     Y C  CG+ F        H +TH
Sbjct: 780  KKIHTGEKPYKCEECGKGFSMFSILTKHEVIHTGEKPYKCEECGKAFSWLSVFSKHKKTH 839

Query: 179  NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
             G+   + +      ++ + + +   +H  E    PYK C  CG  F    +L+EH+K+H
Sbjct: 840  AGEKFYKCEACGKAYNTFSILTKHKVIHTGEK---PYK-CEECGKAFNWSSNLMEHKKIH 895

Query: 239  TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQA 298
            T +T +     +        PSS         L        G+KP +C      F+    
Sbjct: 896  TGETPY---KCEECDKAFSWPSS---------LTEHKATHAGEKPYKCEECGKAFS---- 939

Query: 299  W-QLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGE 357
            W    T+ K     E     +E     + SS+  E    + G       + E+C  S   
Sbjct: 940  WPSRLTEHKATHAGEEPYKCEECGKAFNWSSNLMEHKRIHTGE---KPYKCEECGKSFST 996

Query: 358  APSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQP 417
              S+    K+  + EKP  C ECGKA++    L  H ++H  ++    E           
Sbjct: 997  F-SILTKHKVIHTGEKPYKCEECGKAYKWSSTLSYHKKIHTVEKPYKCEE---------- 1045

Query: 418  GTCSPDLA--APLDENGAVDRGEG---GSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRE 472
              C       + L ++  +  GE      E G     P  +   K    G+  +     +
Sbjct: 1046 --CGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIHTGEKPY-----K 1098

Query: 473  CSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERH 521
            C  CGK F +   L  H   HTGEKPYKCE C  A +  +    H + H
Sbjct: 1099 CEECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSVFSKHKKIH 1147



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 109/431 (25%), Positives = 159/431 (36%), Gaps = 55/431 (12%)

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K  +  E  + C+ CG+ F     +  H   H    +Y C  CG+ F +   L  H   H
Sbjct: 220 KSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEKSYKCEECGKAFNQSAILTKHKIIH 279

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+   + +      S  +T+     +HA E    PYK C  CG  F    +LI H+ +H
Sbjct: 280 TGEKPNKCEECGKAFSKVSTLTTHKAIHAGE---KPYK-CKECGKAFSKVSTLITHKAIH 335

Query: 239 TKK---------TAFGTSSAQTDSP---QGGMPSSREDFLQLF----NLRPKSHPETGKK 282
             +          AF   S  T       G  P   E+  + +     L       TG+K
Sbjct: 336 AGEKPYKCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAYKWPSTLSYHKKIHTGEK 395

Query: 283 PVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCA 342
           P +C      F+ F    + TK +V    E     +E     + SS+  E  + + G   
Sbjct: 396 PYKCEECGKGFSMF---SILTKHEVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHTGE-- 450

Query: 343 GLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRR 402
               + E+C      + ++    K+  + EKP  C ECGKAF     L+ H R+H     
Sbjct: 451 -TPYKCEECGKGFSWSSTLSYHKKI-HTVEKPYKCEECGKAFNQSAILIKHKRIH----- 503

Query: 403 AGAESPTMSVDGRQPGTCSP-----DLAAPLDENGAVDRGEGG---SEDGSEDGLPEGIH 454
                      G +P  C          + L  + A+  GE      E G        + 
Sbjct: 504 ----------TGEKPYKCEECGKTFSKVSTLTTHKAIHAGEKPYKCKECGKTFIKVSTLT 553

Query: 455 LDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSL 514
             K    G+  +     +C  CGK F     L  H   HTGEKPYKCE C  A    ++L
Sbjct: 554 THKAIHAGEKPY-----KCKECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNWSSNL 608

Query: 515 RYHLERHHKEK 525
             H   H  EK
Sbjct: 609 MEHKRIHTGEK 619



 Score = 87.0 bits (214), Expect = 8e-17
 Identities = 96/409 (23%), Positives = 149/409 (36%), Gaps = 77/409 (18%)

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
           +EN + CE  G+ F  +  +  +   H     Y C  CG+ F +   L  H   H G+  
Sbjct: 197 RENSYKCEEGGKAFNWSSTLTYYKSAHTGEKPYRCKECGKAFSKFSILTKHKVIHTGEKS 256

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTA 243
            + +      +  A + +   +H  E    P K C  CG  F    +L  H+ +H  +  
Sbjct: 257 YKCEECGKAFNQSAILTKHKIIHTGEK---PNK-CEECGKAFSKVSTLTTHKAIHAGEKP 312

Query: 244 FGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLAT 303
           +                  + F ++  L        G+KP +C      F+ F    + T
Sbjct: 313 YKCKECG------------KAFSKVSTLITHKAIHAGEKPYKCKECGKAFSKFS---ILT 357

Query: 304 KGKVAI-------CQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHG 356
           K KV         C+E  ++ +  ST     S  K++    K        + E+C     
Sbjct: 358 KHKVIHTGEKPYKCEECGKAYKWPST----LSYHKKIHTGEK------PYKCEECGKGFS 407

Query: 357 EAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQ 416
              S+    ++  + EKP  C ECGKAF     L+ H ++H                G  
Sbjct: 408 MF-SILTKHEVIHTGEKPYKCEECGKAFNWSSNLMEHKKIHT---------------GET 451

Query: 417 PGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYC 476
           P  C              + G+G S   +       +   K     KI  +    +C  C
Sbjct: 452 PYKCE-------------ECGKGFSWSST-------LSYHK-----KIHTVEKPYKCEEC 486

Query: 477 GKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           GK F  +  L  H R HTGEKPYKCE C    ++ ++L  H   H  EK
Sbjct: 487 GKAFNQSAILIKHKRIHTGEKPYKCEECGKTFSKVSTLTTHKAIHAGEK 535



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 45/181 (24%), Positives = 72/181 (39%), Gaps = 15/181 (8%)

Query: 61   GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
            G  P  C  C ++F+    L KH ++    +P  CE               K        
Sbjct: 981  GEKPYKCEECGKSFSTFSILTKHKVIHTGEKPYKCEEC---------GKAYKWSSTLSYH 1031

Query: 119  KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
            K+ +  E  + CE CG+ F +   +  H   H     Y C  CG+ +K P  L+ H + H
Sbjct: 1032 KKIHTVEKPYKCEECGKGFVMFSILAKHKVIHTGEKLYKCEECGKAYKWPSTLRYHKKIH 1091

Query: 179  NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
             G+   + +      S+ + + +   +H  E    PYK C  CG  F       +H+K+H
Sbjct: 1092 TGEKPYKCEECGKAFSTFSILTKHKVIHTGE---KPYK-CEECGKAFSWLSVFSKHKKIH 1147

Query: 239  T 239
            T
Sbjct: 1148 T 1148



 Score = 36.2 bits (82), Expect = 0.17
 Identities = 17/62 (27%), Positives = 24/62 (38%)

Query: 119  KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
            K+ +  E  + CE CG+ F     +  H   H     Y C  CG+ F        H + H
Sbjct: 1088 KKIHTGEKPYKCEECGKAFSTFSILTKHKVIHTGEKPYKCEECGKAFSWLSVFSKHKKIH 1147

Query: 179  NG 180
             G
Sbjct: 1148 TG 1149


>gi|111548668 zinc finger protein 676 [Homo sapiens]
          Length = 588

 Score =  111 bits (277), Expect = 4e-24
 Identities = 113/426 (26%), Positives = 170/426 (39%), Gaps = 59/426 (13%)

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + CE CG+ F     +  H   H     Y C  CG+ F     L  H   H G+   
Sbjct: 194 EKPYKCEECGKAFSKFSILTKHKVIHTGEKPYKCEECGKAFNRSSILTKHKIIHTGEKPY 253

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKK--- 241
           + +      SS +T+N    +HA E    PYK C  CG    +   L+EH+++HT +   
Sbjct: 254 KCEECGKGFSSVSTLNTHKAIHAEE---KPYK-CEECGKASNSSSKLMEHKRIHTGEKPY 309

Query: 242 ------TAFGTSSAQTDSPQ---GGMPSSREDFLQLFN----LRPKSHPETGKKPVRC-- 286
                  AF  SS+ T+  +   G  P   E+  + FN    L       TG+KP +C  
Sbjct: 310 KCEECGKAFSWSSSLTEHKRIHAGEKPYKCEECGKAFNRSSILTKHKIIHTGEKPYKCEG 369

Query: 287 ----IPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCA 342
                 ++    T +A  +  + K   C+E  ++          S+S  +L E  +    
Sbjct: 370 CGKAFSKVSTLNTHKA--IHAEEKPYKCEECGKA----------SNSSSKLMEHKRIHTG 417

Query: 343 GLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRR 402
               + E+C  +   + S+    ++ +  EKP  C ECGKAF        H R+H     
Sbjct: 418 EKPYKCEECGKAFSWSSSLTEHKRIHAG-EKPYKCEECGKAFTWSSSFTKHKRIH----- 471

Query: 403 AGAESPTMSVD-GRQPGTCSPDLAAPLDENGAVDRGEGG---SEDGSEDGLPEGIHLDKN 458
             AE P    + G+   T S      L ++  +  GE      E G        +   K 
Sbjct: 472 -AAEKPYKCEECGKGFSTFS-----ILTKHKIIHTGEKRYKCEECGKAFSWSSILTEHKI 525

Query: 459 DDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHL 518
              G+  +     +C  CGK F  +  L  H R HTGEKPYKCE C  A    +++ YH 
Sbjct: 526 IHTGEKPY-----KCEECGKAFSRSSSLTRHKRIHTGEKPYKCEECGKAFKSSSTVSYHK 580

Query: 519 ERHHKE 524
           + H  E
Sbjct: 581 KIHTGE 586



 Score = 94.4 bits (233), Expect = 5e-19
 Identities = 89/362 (24%), Positives = 141/362 (38%), Gaps = 38/362 (10%)

Query: 54  KNVIQIEGYMPLDCMFCSQTFTHSEDLNKH--VLMQHRPTLCEPAVLRVEAEYLSPLDKS 111
           K+ I   G  P  C  C + F+    LN H  +  + +P  CE                S
Sbjct: 242 KHKIIHTGEKPYKCEECGKGFSSVSTLNTHKAIHAEEKPYKCEEC---------GKASNS 292

Query: 112 QVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFL 171
             +    K  +  E  + CE CG+ F  +  +  H R H     Y C  CG+ F     L
Sbjct: 293 SSKLMEHKRIHTGEKPYKCEECGKAFSWSSSLTEHKRIHAGEKPYKCEECGKAFNRSSIL 352

Query: 172 KNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESL 231
             H   H G+   + +      S  +T+N    +HA E    PYK C  CG    +   L
Sbjct: 353 TKHKIIHTGEKPYKCEGCGKAFSKVSTLNTHKAIHAEE---KPYK-CEECGKASNSSSKL 408

Query: 232 IEHRKVHTKK---------TAFGTSSAQTDSPQ---GGMPSSREDFLQLF----NLRPKS 275
           +EH+++HT +          AF  SS+ T+  +   G  P   E+  + F    +     
Sbjct: 409 MEHKRIHTGEKPYKCEECGKAFSWSSSLTEHKRIHAGEKPYKCEECGKAFTWSSSFTKHK 468

Query: 276 HPETGKKPVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGE 335
                +KP +C      F+TF    + TK K+    E +   +E       SS   E   
Sbjct: 469 RIHAAEKPYKCEECGKGFSTF---SILTKHKIIHTGEKRYKCEECGKAFSWSSILTEHKI 525

Query: 336 TNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSR 395
            + G       + E+C  +   + S+    ++ +  EKP  C ECGKAF++   +  H +
Sbjct: 526 IHTGE---KPYKCEECGKAFSRSSSLTRHKRIHTG-EKPYKCEECGKAFKSSSTVSYHKK 581

Query: 396 VH 397
           +H
Sbjct: 582 IH 583



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 94/403 (23%), Positives = 136/403 (33%), Gaps = 93/403 (23%)

Query: 124 KENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSG 183
           +EN + CE  G+ F  +  +  +   H     Y C  CG+ F +   L  H   H G+  
Sbjct: 165 RENSYKCEENGKAFNWSSTLTYYKSIHTGEKPYKCEECGKAFSKFSILTKHKVIHTGEKP 224

Query: 184 ARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTA 243
            + +      +  + + +   +H  E    PYK C  CG  F +  +L  H+ +H ++  
Sbjct: 225 YKCEECGKAFNRSSILTKHKIIHTGEK---PYK-CEECGKGFSSVSTLNTHKAIHAEEKP 280

Query: 244 FGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLAT 303
           +        S                 L       TG+KP +C                 
Sbjct: 281 YKCEECGKASNSSS------------KLMEHKRIHTGEKPYKC----------------- 311

Query: 304 KGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEK-EKCKHSHGEAPSVD 362
                     +E G+  S     SSS  E    +K   AG    K E+C  +   + S+ 
Sbjct: 312 ----------EECGKAFSW----SSSLTE----HKRIHAGEKPYKCEECGKAFNRS-SIL 352

Query: 363 ADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSP 422
              K+  + EKP  C  CGKAF     L  H  +H +++               P  C  
Sbjct: 353 TKHKIIHTGEKPYKCEGCGKAFSKVSTLNTHKAIHAEEK---------------PYKCE- 396

Query: 423 DLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRS 482
                          E G    S   L E   +   +   K         C  CGK F  
Sbjct: 397 ---------------ECGKASNSSSKLMEHKRIHTGEKPYK---------CEECGKAFSW 432

Query: 483 NYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           +  L  H R H GEKPYKCE C  A    +S   H   H  EK
Sbjct: 433 SSSLTEHKRIHAGEKPYKCEECGKAFTWSSSFTKHKRIHAAEK 475



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 105/503 (20%), Positives = 179/503 (35%), Gaps = 62/503 (12%)

Query: 62  YMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEK 121
           ++ + C    +   H E  NK   +    T  +  V +   +Y +   K    +   K +
Sbjct: 80  HLKISCTNVDECNVHKEGYNK---LNQSLTTTQSKVFQC-GKYANVFHKCS-NSNRHKIR 134

Query: 122 NCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGK 181
           +  E    C+   ++F +   +  H R +    +Y C   G+ F     L  +   H G+
Sbjct: 135 HTGEKGLKCKEYVRSFCMLSHLSQHERIYTRENSYKCEENGKAFNWSSTLTYYKSIHTGE 194

Query: 182 SGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKK 241
              + +      S  + + +   +H  E    PYK C  CG  F     L +H+ +HT +
Sbjct: 195 KPYKCEECGKAFSKFSILTKHKVIHTGE---KPYK-CEECGKAFNRSSILTKHKIIHTGE 250

Query: 242 TAF-------GTSSAQTDSPQGGMPSSREDFL---------QLFNLRPKSHPETGKKPVR 285
             +       G SS  T +    + +  + +              L       TG+KP +
Sbjct: 251 KPYKCEECGKGFSSVSTLNTHKAIHAEEKPYKCEECGKASNSSSKLMEHKRIHTGEKPYK 310

Query: 286 C-------------------IPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDD 326
           C                        P+   +  +   +  +    ++  +G++       
Sbjct: 311 CEECGKAFSWSSSLTEHKRIHAGEKPYKCEECGKAFNRSSILTKHKIIHTGEKPYKCEGC 370

Query: 327 SSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDA---DPKLPSSKEKPTHCSECGKA 383
             +  ++   N        ++  KC+   G+A +  +   + K   + EKP  C ECGKA
Sbjct: 371 GKAFSKVSTLNTHKAIHAEEKPYKCEEC-GKASNSSSKLMEHKRIHTGEKPYKCEECGKA 429

Query: 384 FRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSED 443
           F     L  H R+H  ++    E    +       T    + A        + G+G S  
Sbjct: 430 FSWSSSLTEHKRIHAGEKPYKCEECGKAFTWSSSFTKHKRIHAAEKPYKCEECGKGFSTF 489

Query: 444 GSEDGLPEGIHLDKNDDGGKIKHLTSSR-ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCE 502
                      L K+    KI H    R +C  CGK F  +  L  H   HTGEKPYKCE
Sbjct: 490 SI---------LTKH----KIIHTGEKRYKCEECGKAFSWSSILTEHKIIHTGEKPYKCE 536

Query: 503 FCEYAAAQKTSLRYHLERHHKEK 525
            C  A ++ +SL  H   H  EK
Sbjct: 537 ECGKAFSRSSSLTRHKRIHTGEK 559



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 45/181 (24%), Positives = 69/181 (38%), Gaps = 15/181 (8%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F+ S  L +H  +    +P  CE         + S   K        
Sbjct: 417 GEKPYKCEECGKAFSWSSSLTEHKRIHAGEKPYKCEECGKAFT--WSSSFTKH------- 467

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K  +  E  + CE CG+ F     +  H   H     Y C  CG+ F     L  H   H
Sbjct: 468 KRIHAAEKPYKCEECGKGFSTFSILTKHKIIHTGEKRYKCEECGKAFSWSSILTEHKIIH 527

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+   + +      S  +++    ++H  E    PYK C  CG  F +  ++  H+K+H
Sbjct: 528 TGEKPYKCEECGKAFSRSSSLTRHKRIHTGEK---PYK-CEECGKAFKSSSTVSYHKKIH 583

Query: 239 T 239
           T
Sbjct: 584 T 584



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 35/145 (24%), Positives = 50/145 (34%), Gaps = 25/145 (17%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKH--VLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + FT S    KH  +    +P  CE           S L K ++     
Sbjct: 445 GEKPYKCEECGKAFTWSSSFTKHKRIHAAEKPYKCEECGKGFST--FSILTKHKIIHTGE 502

Query: 119 KEKNCKE---------------------NEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYG 157
           K   C+E                       + CE CG+ F  +  +  H R H     Y 
Sbjct: 503 KRYKCEECGKAFSWSSILTEHKIIHTGEKPYKCEECGKAFSRSSSLTRHKRIHTGEKPYK 562

Query: 158 CNMCGRRFKEPWFLKNHMRTHNGKS 182
           C  CG+ FK    +  H + H G++
Sbjct: 563 CEECGKAFKSSSTVSYHKKIHTGEN 587


>gi|116256455 zinc finger protein 429 [Homo sapiens]
          Length = 674

 Score =  109 bits (273), Expect = 1e-23
 Identities = 118/492 (23%), Positives = 187/492 (38%), Gaps = 68/492 (13%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTL--CEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C ++F     L +H  +  R     C+        E+ +  ++S   T   
Sbjct: 169 GKKPFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCK--------EFGNAFNQSSALTNH- 219

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K     E  + CE CG+ F     +  H R H     Y C  CG+ F     L  H R H
Sbjct: 220 KRIYVGEKHYRCEECGKAFNHYSTLTNHKRIHTGEKPYKCKECGKAFSRYSTLTTHKRIH 279

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
           +G+   +        S  +T  +   +H  E    PYK C  CG  F    +L  H+++H
Sbjct: 280 SGEKPYKCDECGKTFSISSTFTKHKIIHTEEK---PYK-CKECGKAFNRSSTLTSHKRIH 335

Query: 239 TKKTAFGTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDPFT 294
           T                G  P   E+  + FN    L       TG+KP +C      F 
Sbjct: 336 T----------------GEKPYKCEECGKAFNWSSTLTKHKVIHTGEKPYKCEECGKAFN 379

Query: 295 TFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHS 354
             Q+ +L    K+   +E  +  + G      S+    L +  K          E+C   
Sbjct: 380 --QSSRLTRHKKIHTGEEPYKFEKCGRVFTCSST----LTQDKKIHTGEKPYNCEECGKV 433

Query: 355 HGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDR--------RAGAE 406
              + ++    ++  ++EKP  C+ECGKAF     L  H R+H  ++        +A  +
Sbjct: 434 FTYSSTLTRHKRI-HTEEKPYKCNECGKAFNRSSHLTSHRRIHTGEKPYKCEECGKAFKQ 492

Query: 407 SPTMSV-----DGRQPGTCSPD-----LAAPLDENGAVDRGEGG---SEDGSEDGLPEGI 453
           S  ++       G +P  C        L++ L ++  +  GE      E G        +
Sbjct: 493 SSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQHKKIHTGEKPYKCEECGKAFNRSSRL 552

Query: 454 HLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTS 513
              K    G+  +     +C  C K F  +  L+ H + H+GEKPYKCE C  A  + + 
Sbjct: 553 TQHKKIHTGEKPY-----KCKQCDKAFTHSSNLSSHKKIHSGEKPYKCEECGKAFNRSSR 607

Query: 514 LRYHLERHHKEK 525
           L  H + H +EK
Sbjct: 608 LTQHKKIHTREK 619



 Score =  108 bits (270), Expect = 3e-23
 Identities = 112/470 (23%), Positives = 176/470 (37%), Gaps = 72/470 (15%)

Query: 67  CMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCK 124
           C  C + F H   L  H  +    +P  C+    +  + Y      S + T   K  +  
Sbjct: 231 CEECGKAFNHYSTLTNHKRIHTGEKPYKCKECG-KAFSRY------STLTTH--KRIHSG 281

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + C+ CG+TF ++     H   H +   Y C  CG+ F     L +H R H G+   
Sbjct: 282 EKPYKCDECGKTFSISSTFTKHKIIHTEEKPYKCKECGKAFNRSSTLTSHKRIHTGEKPY 341

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           + +      +  +T+ +   +H  E    PYK C  CG  F     L  H+K+HT     
Sbjct: 342 KCEECGKAFNWSSTLTKHKVIHTGE---KPYK-CEECGKAFNQSSRLTRHKKIHT----- 392

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLF----NLRPKSHPETGKKPVRCIPQLDPFTTFQAW- 299
                      G  P   E   ++F     L       TG+KP  C      FT      
Sbjct: 393 -----------GEEPYKFEKCGRVFTCSSTLTQDKKIHTGEKPYNCEECGKVFTYSSTLT 441

Query: 300 ---QLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHG 356
              ++ T+ K   C E  ++    S      +S + +    K        + E+C  +  
Sbjct: 442 RHKRIHTEEKPYKCNECGKAFNRSS----HLTSHRRIHTGEK------PYKCEECGKAFK 491

Query: 357 EAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQ 416
           ++ ++++  K+ S  EKP  C ECGKAF    +L  H ++H                G +
Sbjct: 492 QSSNLNSHKKIHSG-EKPYKCEECGKAFILSSRLTQHKKIH---------------TGEK 535

Query: 417 PGTCSP-----DLAAPLDENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSR 471
           P  C       + ++ L ++  +  GE   +    D      H        KI       
Sbjct: 536 PYKCEECGKAFNRSSRLTQHKKIHTGEKPYKCKQCD--KAFTHSSNLSSHKKIHSGEKPY 593

Query: 472 ECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERH 521
           +C  CGK F  +  L  H + HT EKPYKCE C  A  + + L  H + H
Sbjct: 594 KCEECGKAFNRSSRLTQHKKIHTREKPYKCEECAKAFTRSSRLTQHKKIH 643



 Score =  104 bits (259), Expect = 5e-22
 Identities = 109/445 (24%), Positives = 168/445 (37%), Gaps = 55/445 (12%)

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K ++  +  F C+ CG++F +   +  H + H    TY C   G  F +   L NH R +
Sbjct: 164 KTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCKEFGNAFNQSSALTNHKRIY 223

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
            G+   R +      +  +T+    ++H  E    PYK C  CG  F    +L  H+++H
Sbjct: 224 VGEKHYRCEECGKAFNHYSTLTNHKRIHTGE---KPYK-CKECGKAFSRYSTLTTHKRIH 279

Query: 239 TKK---------TAFGTSSA-------QTDSPQGGMPSSREDFLQLFNLRPKSHPETGKK 282
           + +           F  SS         T+          + F +   L       TG+K
Sbjct: 280 SGEKPYKCDECGKTFSISSTFTKHKIIHTEEKPYKCKECGKAFNRSSTLTSHKRIHTGEK 339

Query: 283 PVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQE-GSTDNDDSSSEKELGETNKGSC 341
           P +C    +    F      TK KV    E     +E G   N  S     L    K   
Sbjct: 340 PYKC---EECGKAFNWSSTLTKHKVIHTGEKPYKCEECGKAFNQSS----RLTRHKKIHT 392

Query: 342 AGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKD- 400
                + EKC      + ++  D K+ +  EKP +C ECGK F     L  H R+H ++ 
Sbjct: 393 GEEPYKFEKCGRVFTCSSTLTQDKKIHTG-EKPYNCEECGKVFTYSSTLTRHKRIHTEEK 451

Query: 401 ------------RRAGAESPTMSVDGRQPGTCSP-----DLAAPLDENGAVDRGEGG--- 440
                       R +   S      G +P  C         ++ L+ +  +  GE     
Sbjct: 452 PYKCNECGKAFNRSSHLTSHRRIHTGEKPYKCEECGKAFKQSSNLNSHKKIHSGEKPYKC 511

Query: 441 SEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYK 500
            E G    L   +   K    G+  +     +C  CGK F  +  L  H + HTGEKPYK
Sbjct: 512 EECGKAFILSSRLTQHKKIHTGEKPY-----KCEECGKAFNRSSRLTQHKKIHTGEKPYK 566

Query: 501 CEFCEYAAAQKTSLRYHLERHHKEK 525
           C+ C+ A    ++L  H + H  EK
Sbjct: 567 CKQCDKAFTHSSNLSSHKKIHSGEK 591



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 99/405 (24%), Positives = 154/405 (38%), Gaps = 49/405 (12%)

Query: 128 FSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSK 187
           + C++  + F    + + +   H     + C  CG+ F     L  H + H  ++  R K
Sbjct: 145 YHCDIYVKVFYAFSNADRYKTRHTGKKPFQCKKCGKSFCMLSQLTQHKKIHIRENTYRCK 204

Query: 188 -LQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAFGT 246
                   S A  N     H    +   +  C  CG  F +  +L  H+++HT +  +  
Sbjct: 205 EFGNAFNQSSALTN-----HKRIYVGEKHYRCEECGKAFNHYSTLTNHKRIHTGEKPYKC 259

Query: 247 SSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKKPVRCIPQLDPFTTFQAWQLATKGK 306
                           + F +   L       +G+KP +C    +   TF      TK K
Sbjct: 260 KEC------------GKAFSRYSTLTTHKRIHSGEKPYKCD---ECGKTFSISSTFTKHK 304

Query: 307 VAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEA---PSVDA 363
           +   +E     +E     + SS+       + G      ++  KC+   G+A    S   
Sbjct: 305 IIHTEEKPYKCKECGKAFNRSSTLTSHKRIHTG------EKPYKCEEC-GKAFNWSSTLT 357

Query: 364 DPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPD 423
             K+  + EKP  C ECGKAF    +L  H ++H      G E       GR   TCS  
Sbjct: 358 KHKVIHTGEKPYKCEECGKAFNQSSRLTRHKKIH-----TGEEPYKFEKCGR-VFTCS-- 409

Query: 424 LAAPLDENGAVDRGE---GGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFF 480
             + L ++  +  GE      E G        +   K     +I       +C+ CGK F
Sbjct: 410 --STLTQDKKIHTGEKPYNCEECGKVFTYSSTLTRHK-----RIHTEEKPYKCNECGKAF 462

Query: 481 RSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
             + +L  H R HTGEKPYKCE C  A  Q ++L  H + H  EK
Sbjct: 463 NRSSHLTSHRRIHTGEKPYKCEECGKAFKQSSNLNSHKKIHSGEK 507



 Score = 73.6 bits (179), Expect = 9e-13
 Identities = 51/215 (23%), Positives = 89/215 (41%), Gaps = 27/215 (12%)

Query: 51  TQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKH--VLMQHRPTLC-EPAVLRVEAEYLSP 107
           TQ+K +    G  P +C  C + FT+S  L +H  +  + +P  C E       + +L+ 
Sbjct: 413 TQDKKIHT--GEKPYNCEECGKVFTYSSTLTRHKRIHTEEKPYKCNECGKAFNRSSHLTS 470

Query: 108 LDKSQVRTEPPKEKNCK------------------ENEFSCEVCGQTFRVAFDVEIHMRT 149
             +     +P K + C                   E  + CE CG+ F ++  +  H + 
Sbjct: 471 HRRIHTGEKPYKCEECGKAFKQSSNLNSHKKIHSGEKPYKCEECGKAFILSSRLTQHKKI 530

Query: 150 HKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAE 209
           H     Y C  CG+ F     L  H + H G+   + K      +  + ++   ++H+ E
Sbjct: 531 HTGEKPYKCEECGKAFNRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSHKKIHSGE 590

Query: 210 SISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
               PYK C  CG  F     L +H+K+HT++  +
Sbjct: 591 ---KPYK-CEECGKAFNRSSRLTQHKKIHTREKPY 621



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 48/199 (24%), Positives = 78/199 (39%), Gaps = 15/199 (7%)

Query: 61  GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
           G  P  C  C + F  S +LN H  +    +P  CE      +A  LS       R    
Sbjct: 477 GEKPYKCEECGKAFKQSSNLNSHKKIHSGEKPYKCEECG---KAFILSS------RLTQH 527

Query: 119 KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
           K+ +  E  + CE CG+ F  +  +  H + H     Y C  C + F     L +H + H
Sbjct: 528 KKIHTGEKPYKCEECGKAFNRSSRLTQHKKIHTGEKPYKCKQCDKAFTHSSNLSSHKKIH 587

Query: 179 NGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVH 238
           +G+   + +      +  + + +  ++H  E    PYK C  C   F     L +H+K+H
Sbjct: 588 SGEKPYKCEECGKAFNRSSRLTQHKKIHTREK---PYK-CEECAKAFTRSSRLTQHKKIH 643

Query: 239 TKKTAFGTSSAQTDSPQGG 257
                    +  T   +GG
Sbjct: 644 RMGVVAHACNPSTLGGRGG 662



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 30/130 (23%), Positives = 43/130 (33%), Gaps = 37/130 (28%)

Query: 49  RATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPL 108
           R TQ K +    G  P  C  C + FTHS +L+ H                         
Sbjct: 551 RLTQHKKIHT--GEKPYKCKQCDKAFTHSSNLSSH------------------------- 583

Query: 109 DKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEP 168
                     K+ +  E  + CE CG+ F  +  +  H + H     Y C  C + F   
Sbjct: 584 ----------KKIHSGEKPYKCEECGKAFNRSSRLTQHKKIHTREKPYKCEECAKAFTRS 633

Query: 169 WFLKNHMRTH 178
             L  H + H
Sbjct: 634 SRLTQHKKIH 643


>gi|118600985 zinc finger protein 91 [Homo sapiens]
          Length = 1191

 Score =  109 bits (272), Expect = 2e-23
 Identities = 129/502 (25%), Positives = 191/502 (38%), Gaps = 72/502 (14%)

Query: 67  CMFCSQTFTHSEDLNKH--VLMQHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCK 124
           C  C +TF  S  L  H  +  + +P  CE      +   LS L   ++          K
Sbjct: 212 CKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQ--LSTLTTHKIIC-------AK 262

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + CE CG+ F  +  +  H R H     Y C  CG+ F     L  H R H G+   
Sbjct: 263 EKIYKCEECGKAFLWSSTLTRHKRIHTGEKPYKCEECGKAFSHSSTLAKHKRIHTGEKPY 322

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKK--- 241
           + +      S  +T+ +  ++H  E    PYK C  CG  F N  +L  H+  HT++   
Sbjct: 323 KCEECGKAFSRSSTLAKHKRIHTGE---KPYK-CKECGKAFSNSSTLANHKITHTEEKPY 378

Query: 242 ------TAFGTSSAQTDSP---QGGMPSSRED----FLQLFNLRPKSHPETGKKPVRCIP 288
                  AF   S  T       G      E+    F +  NL       TG+KP +C  
Sbjct: 379 KCKECDKAFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEE 438

Query: 289 QLDPFTTFQAW----QLATKGKVAICQEVKESGQEGST---DNDDSSSEK--ELGETNKG 339
               F    +     +  T+ K   C+E  ++    ST        + EK  +  E  K 
Sbjct: 439 CGKAFNWSSSLTKHKRFHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKA 498

Query: 340 SCAGLSQEKEKCKHSHGEAPSVDAD-------------PKLPSSKEKPTHCSECGKAFRT 386
                +  K K  H+ GE P    +              K+  S+EKP  C ECGKAF+ 
Sbjct: 499 FRQSSTLTKHKIIHT-GEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQ 557

Query: 387 YHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGG---SED 443
           +  L  H  +H     AG +       G+     + + ++ L  +  +  GE      E 
Sbjct: 558 FSTLTTHKIIH-----AGKKLYKCEECGK-----AFNHSSSLSTHKIIHTGEKSYKCEEC 607

Query: 444 GSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEF 503
           G        +   K    G+  +     +C  CGK F  +  L  H R HTGEKPYKC+ 
Sbjct: 608 GKAFLWSSTLRRHKRIHTGEKPY-----KCEECGKAFSHSSALAKHKRIHTGEKPYKCKE 662

Query: 504 CEYAAAQKTSLRYHLERHHKEK 525
           C  A +  ++L  H   H +EK
Sbjct: 663 CGKAFSNSSTLANHKITHTEEK 684



 Score =  108 bits (269), Expect = 3e-23
 Identities = 121/477 (25%), Positives = 175/477 (36%), Gaps = 78/477 (16%)

Query: 67  CMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPPKEKNCK 124
           C  C + F HS  L+ H ++    +   CE             L  S +R    K  +  
Sbjct: 576 CEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAF-------LWSSTLRRH--KRIHTG 626

Query: 125 ENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTHNGKSGA 184
           E  + CE CG+ F  +  +  H R H     Y C  CG+ F     L NH  TH  +   
Sbjct: 627 EKPYKCEECGKAFSHSSALAKHKRIHTGEKPYKCKECGKAFSNSSTLANHKITHTEEKPY 686

Query: 185 RSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEHRKVHTKKTAF 244
           + K         +T+ +   +HA E +   YK C  CG  F    +L  H+ +HT     
Sbjct: 687 KCKECDKTFKRLSTLTKHKIIHAGEKL---YK-CEECGKAFNRSSNLTIHKFIHT----- 737

Query: 245 GTSSAQTDSPQGGMPSSREDFLQLFN----LRPKSHPETGKKPVRCIPQLDPF----TTF 296
                      G  P   E+  + FN    L       T +KP +C      F    T  
Sbjct: 738 -----------GEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSSTLT 786

Query: 297 QAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCAGLSQEKEKCKHSHG 356
           +  ++ T  K   C+E  ++    ST               K       ++  KCK   G
Sbjct: 787 RHKRIHTGEKPYKCEECGKAFSRSST-------------LTKHKTIHTGEKPYKCKEC-G 832

Query: 357 EA---PSVDADPKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVD 413
           +A    S  A  K+  + EK   C ECGKAF     L  H  +H K++ + +E       
Sbjct: 833 KAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEE------ 886

Query: 414 GRQPGTCSPDL--AAPLDENGAVDRGEGG---SEDGSEDGLPEGIHLDKNDDGGKIKHLT 468
                 C      ++ L E+  +   E      E G     P  +   K    G+  +  
Sbjct: 887 ------CDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPY-- 938

Query: 469 SSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
              +C  CGK F  +  L  H   HTGEKPYKCE C  A  + ++L  H   H  EK
Sbjct: 939 ---KCEECGKAFSQSSTLTTHKIIHTGEKPYKCEECGKAFRKSSTLTEHKIIHTGEK 992



 Score =  107 bits (268), Expect = 4e-23
 Identities = 124/516 (24%), Positives = 188/516 (36%), Gaps = 116/516 (22%)

Query: 61   GYMPLDCMFCSQTFTHSEDLNKHVLM--QHRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
            G  P  C  C + F++S  L  H +   + +P  C+      +   LS L K ++     
Sbjct: 654  GEKPYKCKECGKAFSNSSTLANHKITHTEEKPYKCKECDKTFKR--LSTLTKHKIIHAGE 711

Query: 119  KEKNCKE---------------------NEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYG 157
            K   C+E                       + CE CG+ F  +  +  H R H     + 
Sbjct: 712  KLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFK 771

Query: 158  CNMCGRRFKEPWFLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKI 217
            C  CG+ F     L  H R H G+   + +      S  +T+ +   +H  E    PYK 
Sbjct: 772  CKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSRSSTLTKHKTIHTGEK---PYK- 827

Query: 218  CMVCGFLFPNKESLIEHRKVHTKKT---------AFGTSSAQTDSP---QGGMPSSRED- 264
            C  CG  F +  +L +H+ +H  +          AF  SS  T          PS  E+ 
Sbjct: 828  CKECGKAFKHSSALAKHKIIHAGEKLYKCEECGKAFNQSSNLTTHKIIHTKEKPSKSEEC 887

Query: 265  ---FLQLFNLRPKSHPETGKKPVRC------IPQLDPFTTFQAWQLATKGKVAICQEVKE 315
               F+    L       T +K  +C        Q    TT +  ++ T  K   C+E  +
Sbjct: 888  DKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHK--RMHTGEKPYKCEECGK 945

Query: 316  SGQEGSTDNDDSSSEKELGETNKGSCAGLSQEK-EKCKHSHGEAPSVDADPKLPSSKEKP 374
            +  + ST             T+K    G    K E+C  +  ++ ++  + K+  + EKP
Sbjct: 946  AFSQSSTLT-----------THKIIHTGEKPYKCEECGKAFRKSSTL-TEHKIIHTGEKP 993

Query: 375  THCSECGKAFRTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSP-----DLAAPLD 429
              C ECGKAF     L  H+R+H                G +P  C       + ++ L 
Sbjct: 994  YKCEECGKAFSQSSTLTRHTRMH---------------TGEKPYKCEECGKAFNRSSKLT 1038

Query: 430  ENGAVDRGEGGSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIH 489
             +  +  GE                                 +C  CGK F S+  LN H
Sbjct: 1039 THKIIHTGE------------------------------KPYKCEECGKAFISSSTLNGH 1068

Query: 490  LRTHTGEKPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
             R HT EKPYKCE C  A +Q ++L  H   H  EK
Sbjct: 1069 KRIHTREKPYKCEECGKAFSQSSTLTRHKRLHTGEK 1104



 Score =  107 bits (266), Expect = 8e-23
 Identities = 122/502 (24%), Positives = 189/502 (37%), Gaps = 74/502 (14%)

Query: 50   ATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSP 107
            +T  K+ I   G     C  C + F  S +L  H  +    +P  CE         + S 
Sbjct: 699  STLTKHKIIHAGEKLYKCEECGKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFN--WSSS 756

Query: 108  LDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKE 167
            L K        K  + +E  F C+ CG+ F  +  +  H R H     Y C  CG+ F  
Sbjct: 757  LTKH-------KRIHTREKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFSR 809

Query: 168  PWFLKNHMRTHNGKSGARSK-LQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFP 226
               L  H   H G+   + K   +  + S A     + +HA E +   YK C  CG  F 
Sbjct: 810  SSTLTKHKTIHTGEKPYKCKECGKAFKHSSALAKHKI-IHAGEKL---YK-CEECGKAFN 864

Query: 227  NKESLIEHRKVHTKKT---------AFGTSSAQTDSPQGGMPSSR-------EDFLQLFN 270
               +L  H+ +HTK+          AF  SS  T+  +              + F Q  +
Sbjct: 865  QSSNLTTHKIIHTKEKPSKSEECDKAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSH 924

Query: 271  LRPKSHPETGKKPVRC------IPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDN 324
            L       TG+KP +C        Q    TT +   + T  K   C+E  ++ ++ ST  
Sbjct: 925  LTTHKRMHTGEKPYKCEECGKAFSQSSTLTTHKI--IHTGEKPYKCEECGKAFRKSST-- 980

Query: 325  DDSSSEKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAF 384
                +E ++  T +        + E+C  +  ++ ++    ++ +  EKP  C ECGKAF
Sbjct: 981  ---LTEHKIIHTGEKP-----YKCEECGKAFSQSSTLTRHTRMHTG-EKPYKCEECGKAF 1031

Query: 385  RTYHQLVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENG-----AVDRGEG 439
                +L  H  +H  ++    E             C     +    NG       ++   
Sbjct: 1032 NRSSKLTTHKIIHTGEKPYKCEE------------CGKAFISSSTLNGHKRIHTREKPYK 1079

Query: 440  GSEDGSEDGLPEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPY 499
              E G        +   K    G+  +     +C  CGK F+ +  L  H   HTGEKPY
Sbjct: 1080 CEECGKAFSQSSTLTRHKRLHTGEKPY-----KCGECGKAFKESSALTKHKIIHTGEKPY 1134

Query: 500  KCEFCEYAAAQKTSLRYHLERH 521
            KCE C  A  Q + L  H + H
Sbjct: 1135 KCEKCGKAFNQSSILTNHKKIH 1156



 Score =  106 bits (264), Expect = 1e-22
 Identities = 114/496 (22%), Positives = 187/496 (37%), Gaps = 54/496 (10%)

Query: 50  ATQEKNVIQIEGYMPLDCMFCSQTFTHSEDLNKHVLMQHRPTLCEPAVLRVEAEYLSPLD 109
           +T  K+ I   G  P     C + F  S  LNKH ++  R    +        +  S L 
Sbjct: 503 STLTKHKIIHTGEKPYKFEECGKAFRQSLTLNKHKIIHSREKPYKCKECGKAFKQFSTLT 562

Query: 110 KSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPW 169
             ++        +  +  + CE CG+ F  +  +  H   H    +Y C  CG+ F    
Sbjct: 563 THKII-------HAGKKLYKCEECGKAFNHSSSLSTHKIIHTGEKSYKCEECGKAFLWSS 615

Query: 170 FLKNHMRTHNGKSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKE 229
            L+ H R H G+   + +      S  + + +  ++H  E    PYK C  CG  F N  
Sbjct: 616 TLRRHKRIHTGEKPYKCEECGKAFSHSSALAKHKRIHTGE---KPYK-CKECGKAFSNSS 671

Query: 230 SLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSR----------------EDFLQLFNLRP 273
           +L  H+  HT++  +          +    +                  + F +  NL  
Sbjct: 672 TLANHKITHTEEKPYKCKECDKTFKRLSTLTKHKIIHAGEKLYKCEECGKAFNRSSNLTI 731

Query: 274 KSHPETGKKPVRCIPQLDPFTTFQAW----QLATKGKVAICQEVKESGQEGSTDNDDSSS 329
                TG+KP +C      F    +     ++ T+ K   C+E  ++    ST     + 
Sbjct: 732 HKFIHTGEKPYKCEECGKAFNWSSSLTKHKRIHTREKPFKCKECGKAFIWSST----LTR 787

Query: 330 EKELGETNKGSCAGLSQEKEKCKHSHGEAPSVDADPKLPSSKEKPTHCSECGKAFRTYHQ 389
            K +    K        + E+C  +   + ++    K   + EKP  C ECGKAF+    
Sbjct: 788 HKRIHTGEK------PYKCEECGKAFSRSSTL-TKHKTIHTGEKPYKCKECGKAFKHSSA 840

Query: 390 LVLHSRVHKKDRRAGAESPTMSVDGRQPGTCSPDLAAPLDENGAVDRGEGGSEDGSEDGL 449
           L  H  +H  ++    E    +           + ++ L  +  +   E  S+  SE+  
Sbjct: 841 LAKHKIIHAGEKLYKCEECGKAF----------NQSSNLTTHKIIHTKEKPSK--SEECD 888

Query: 450 PEGIHLDKNDDGGKIKHLTSSRECSYCGKFFRSNYYLNIHLRTHTGEKPYKCEFCEYAAA 509
              I      +  +I     + +C  CGK F    +L  H R HTGEKPYKCE C  A +
Sbjct: 889 KAFIWSSTLTEHKRIHTREKTYKCEECGKAFSQPSHLTTHKRMHTGEKPYKCEECGKAFS 948

Query: 510 QKTSLRYHLERHHKEK 525
           Q ++L  H   H  EK
Sbjct: 949 QSSTLTTHKIIHTGEK 964



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 109/449 (24%), Positives = 174/449 (38%), Gaps = 74/449 (16%)

Query: 108 LDKSQVRTEPPKEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKE 167
           L K+Q +     EK+CK     C+ C +TF  +  +  H   H +   Y C  CG+ FK+
Sbjct: 195 LHKTQHKCVYITEKSCK-----CKECEKTFHWSSTLTNHKEIHTEDKPYKCEECGKAFKQ 249

Query: 168 PWFLKNHMRTHNGKSGARSKLQQGLESSPA-----TINEVVQVHAAESISSPYKICMVCG 222
              L  H         A+ K+ +  E   A     T+    ++H  E    PYK C  CG
Sbjct: 250 LSTLTTHKIIC-----AKEKIYKCEECGKAFLWSSTLTRHKRIHTGEK---PYK-CEECG 300

Query: 223 FLFPNKESLIEHRKVHTKKTAFGTSSAQTDSPQGGMPSSREDFLQLFNLRPKSHPETGKK 282
             F +  +L +H+++HT +  +            G   SR        L       TG+K
Sbjct: 301 KAFSHSSTLAKHKRIHTGEKPYKCEEC-------GKAFSRSS-----TLAKHKRIHTGEK 348

Query: 283 PVRCIPQLDPFTTFQAWQLATKGKVAICQEVKESGQEGSTDNDDSSSEKELGETNKGSCA 342
           P +C          +  +  +        ++  + ++     +   + K L    K    
Sbjct: 349 PYKCK---------ECGKAFSNSSTLANHKITHTEEKPYKCKECDKAFKRLSTLTKHKII 399

Query: 343 GLSQEKEKCKHSHGEAPSVDAD---PKLPSSKEKPTHCSECGKAFRTYHQLVLHSRVHKK 399
              ++  KC+   G+A +  ++    K   + EKP  C ECGKAF     L  H R H +
Sbjct: 400 HAGEKLYKCEEC-GKAFNRSSNLTIHKFIHTGEKPYKCEECGKAFNWSSSLTKHKRFHTR 458

Query: 400 DR--------RAGAESPTMS-----VDGRQPGTCSP-----DLAAPLDENGAVDRGEGGS 441
           ++        +A   S T++       G +P  C         ++ L ++  +  GE   
Sbjct: 459 EKPFKCKECGKAFIWSSTLTRHKRIHTGEKPYKCEECGKAFRQSSTLTKHKIIHTGEKPY 518

Query: 442 E-DGSEDGLPEGIHLDKNDDGGKIKHLTSSRE----CSYCGKFFRSNYYLNIHLRTHTGE 496
           + +       + + L+K+    KI H   SRE    C  CGK F+    L  H   H G+
Sbjct: 519 KFEECGKAFRQSLTLNKH----KIIH---SREKPYKCKECGKAFKQFSTLTTHKIIHAGK 571

Query: 497 KPYKCEFCEYAAAQKTSLRYHLERHHKEK 525
           K YKCE C  A    +SL  H   H  EK
Sbjct: 572 KLYKCEECGKAFNHSSSLSTHKIIHTGEK 600



 Score = 70.5 bits (171), Expect = 8e-12
 Identities = 56/185 (30%), Positives = 76/185 (41%), Gaps = 23/185 (12%)

Query: 61   GYMPLDCMFCSQTFTHSEDLNKHVLMQ--HRPTLCEPAVLRVEAEYLSPLDKSQVRTEPP 118
            G  P  C  C + F+ S  L +H  M    +P  CE        E     ++S   T   
Sbjct: 990  GEKPYKCEECGKAFSQSSTLTRHTRMHTGEKPYKCE--------ECGKAFNRSSKLTTH- 1040

Query: 119  KEKNCKENEFSCEVCGQTFRVAFDVEIHMRTHKDSFTYGCNMCGRRFKEPWFLKNHMRTH 178
            K  +  E  + CE CG+ F  +  +  H R H     Y C  CG+ F +   L  H R H
Sbjct: 1041 KIIHTGEKPYKCEECGKAFISSSTLNGHKRIHTREKPYKCEECGKAFSQSSTLTRHKRLH 1100

Query: 179  NG----KSGARSKLQQGLESSPATINEVVQVHAAESISSPYKICMVCGFLFPNKESLIEH 234
             G    K G   K  +  ESS  T ++++  H  E    PYK C  CG  F     L  H
Sbjct: 1101 TGEKPYKCGECGKAFK--ESSALTKHKII--HTGEK---PYK-CEKCGKAFNQSSILTNH 1152

Query: 235  RKVHT 239
            +K+HT
Sbjct: 1153 KKIHT 1157



 Score = 30.8 bits (68), Expect = 7.0
 Identities = 17/57 (29%), Positives = 27/57 (47%), Gaps = 7/57 (12%)

Query: 468 TSSRECSYCGKFFRSNYYL---NIHLRTHTGEKPYKCEFCEYAAAQKTSLRYHLERH 521
           T+  +   CGK+ +  Y     N H   HTG+K +KC+ C     +   +R H  +H
Sbjct: 148 TAQSKVFQCGKYLKVFYKFLNSNRHTIRHTGKKCFKCKKC----VKSFCIRLHKTQH 200


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,687,598
Number of Sequences: 37866
Number of extensions: 2591380
Number of successful extensions: 49120
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1048
Number of HSP's successfully gapped in prelim test: 234
Number of HSP's that attempted gapping in prelim test: 8208
Number of HSP's gapped (non-prelim): 20998
length of query: 1048
length of database: 18,247,518
effective HSP length: 113
effective length of query: 935
effective length of database: 13,968,660
effective search space: 13060697100
effective search space used: 13060697100
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press