BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] (1336 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 2897 0.0 gi|55743159 WD repeat domain 33 isoform 3 [Homo sapiens] 510 e-144 gi|55743157 WD repeat domain 33 isoform 2 [Homo sapiens] 441 e-123 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 262 2e-69 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 249 1e-65 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 248 3e-65 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 248 3e-65 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 248 3e-65 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 247 6e-65 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 247 6e-65 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 247 6e-65 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 243 9e-64 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 237 5e-62 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 237 5e-62 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 237 5e-62 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 234 4e-61 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 233 9e-61 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 232 2e-60 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 221 5e-57 gi|48762934 alpha 2 type I collagen [Homo sapiens] 219 2e-56 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 218 2e-56 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 218 3e-56 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 215 2e-55 gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 213 8e-55 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 210 6e-54 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 206 9e-53 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 206 9e-53 gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 205 3e-52 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 204 4e-52 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 204 4e-52 >gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] Length = 1336 Score = 2897 bits (7511), Expect = 0.0 Identities = 1336/1336 (100%), Positives = 1336/1336 (100%) Query: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN Sbjct: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60 Query: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC Sbjct: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120 Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD Sbjct: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180 Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL Sbjct: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240 Query: 241 RGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNG 300 RGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNG Sbjct: 241 RGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNG 300 Query: 301 NWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWH 360 NWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWH Sbjct: 301 NWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWH 360 Query: 361 VGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLL 420 VGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLL Sbjct: 361 VGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFWTRNRPGDKMRDRYNLNLL 420 Query: 421 PGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNEIEMTIPGLDWGMEE 480 PGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNEIEMTIPGLDWGMEE Sbjct: 421 PGMSEDGVEYDDLEPNSLAVIPGMGIPEQLKLAMEQEQMGKDESNEIEMTIPGLDWGMEE 480 Query: 481 VMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAE 540 VMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAE Sbjct: 481 VMQKDQKKVPQKKVPYAKPIPAQFQQAWMQNKVPIPAPNEVLNDRKEDIKLEEKKKTQAE 540 Query: 541 IEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQG 600 IEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQG Sbjct: 541 IEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQG 600 Query: 601 FQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQG 660 FQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQG Sbjct: 601 FQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQG 660 Query: 661 PPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQ 720 PPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQ Sbjct: 661 PPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQ 720 Query: 721 GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN 780 GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN Sbjct: 721 GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN 780 Query: 781 PRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP 840 PRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP Sbjct: 781 PRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP 840 Query: 841 PQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPI 900 PQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPI Sbjct: 841 PQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPI 900 Query: 901 PFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSR 960 PFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSR Sbjct: 901 PFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSR 960 Query: 961 GPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFH 1020 GPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFH Sbjct: 961 GPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFH 1020 Query: 1021 PDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGR 1080 PDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGR Sbjct: 1021 PDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGR 1080 Query: 1081 RPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASE 1140 RPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASE Sbjct: 1081 RPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASE 1140 Query: 1141 EAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPR 1200 EAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPR Sbjct: 1141 EAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPR 1200 Query: 1201 PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGK 1260 PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGK Sbjct: 1201 PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGK 1260 Query: 1261 GRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMN 1320 GRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMN Sbjct: 1261 GRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMN 1320 Query: 1321 SGPPRRGASRGGGRGR 1336 SGPPRRGASRGGGRGR Sbjct: 1321 SGPPRRGASRGGGRGR 1336 >gi|55743159 WD repeat domain 33 isoform 3 [Homo sapiens] Length = 257 Score = 510 bits (1314), Expect = e-144 Identities = 241/241 (100%), Positives = 241/241 (100%) Query: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN Sbjct: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60 Query: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC Sbjct: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120 Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD Sbjct: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180 Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL Sbjct: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERIL 240 Query: 241 R 241 R Sbjct: 241 R 241 Score = 42.4 bits (98), Expect = 0.003 Identities = 25/114 (21%), Positives = 48/114 (42%), Gaps = 3/114 (2%) Query: 210 FSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQP 269 ++P + T + G +W+ L + E IL+ H + V+ + W +++ D Sbjct: 127 WTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTA--DHGGY 184 Query: 270 IKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRDHLCKLFDIRNLKEE 323 +K+W ++ AHK + E + N T S D +++D EE Sbjct: 185 VKYWQSNM-NNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEE 237 >gi|55743157 WD repeat domain 33 isoform 2 [Homo sapiens] Length = 326 Score = 441 bits (1135), Expect = e-123 Identities = 209/210 (99%), Positives = 209/210 (99%) Query: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN Sbjct: 1 MATEIGSPPRFFHMPRFQHQAPRQLFYKRPDFAQQQAMQQLTFDGKRMRKAVNRKTIDYN 60 Query: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC Sbjct: 61 PSVIKYLENRIWQRDQRDMRAIQPDAGYYNDLVPPIGMLNNPMNAVTTKFVRTSTNKVKC 120 Query: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD Sbjct: 121 PVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTAD 180 Query: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREASF 210 HGGYVKYWQSNMNNVKMFQAHKEAIREA F Sbjct: 181 HGGYVKYWQSNMNNVKMFQAHKEAIREARF 210 Score = 33.5 bits (75), Expect = 1.4 Identities = 18/86 (20%), Positives = 38/86 (44%), Gaps = 3/86 (3%) Query: 210 FSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQP 269 ++P + T + G +W+ L + E IL+ H + V+ + W +++ D Sbjct: 127 WTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTA--DHGGY 184 Query: 270 IKFWDPKTGQSLATLHAHKNTVMEVK 295 +K+W ++ AHK + E + Sbjct: 185 VKYWQSNM-NNVKMFQAHKEAIREAR 209 Score = 31.6 bits (70), Expect = 5.3 Identities = 23/90 (25%), Positives = 40/90 (44%), Gaps = 8/90 (8%) Query: 247 VKC----VDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNW 302 VKC V W P +V+G+ + W+ T L AH + V + + N W Sbjct: 118 VKCPVFVVRWTPEGRRLVTGASSGE--FTLWNGLTFNFETILQAHDSPVRAMTWSHNDMW 175 Query: 303 LLTASRDHLCKLFDIRNLKEELQVFRGHKK 332 +LTA K + ++ +++F+ HK+ Sbjct: 176 MLTADHGGYVKYW--QSNMNNVKMFQAHKE 203 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 262 bits (669), Expect = 2e-69 Identities = 253/769 (32%), Positives = 304/769 (39%), Gaps = 139/769 (18%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 GPPGP G G G++GP+G P G GP+G +GP+GP GPP G P G GM Sbjct: 652 GPPGPPGDDGERGDDGEVGPRGLP---GEPGPRGLLGPKGPPGPP-GPP------GVTGM 701 Query: 678 QRHPGPHGPLGPQGPPGP---QGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP 734 PGP G +GPQG PGP QG+ G QG GPQG GP G GP G PG G G GP Sbjct: 702 DGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGP 761 Query: 735 PGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-------------------PVSQGP 775 PG G +GPPG +G QGPP P G G PG +G++G P +G Sbjct: 762 PGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGD 821 Query: 776 LMGLNPRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPG--------GLLGH-GPQ 825 + RG GPPGPR GP P+G G P + PPG GL G+ G Q Sbjct: 822 MGIKGDRGEIGPPGPRGEDGPEGPKG--RGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ 879 Query: 826 EMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGP 883 +G G G + G P G PG + Q+GP P+G GP G GP G Sbjct: 880 GPKGSIGFPGFPGANGEKGGRGTP----GKPGPRGQRGPTGPRGERGPRGITGKPGPKGN 935 Query: 884 QGQQNPA-----RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG-LGQQ 937 G PA RGP+ QGP F K GP P ++G P PG G+ Sbjct: 936 SGGDGPAGPPGERGPNGPQGPTGFPGPK------GPPGPPGKDGL-----PGHPGQRGET 984 Query: 938 GAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCR 997 G QG+ P P GP P GPM ER H GP G + + Sbjct: 985 GFQGKTGPPGPPGVVGPQ------GPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTK 1038 Query: 998 GPPDRRG-PHPDFPDDFSRPDDFHPDKRFGHRLREFEG-RGGPLPQEEKWRRGGPGPPFP 1055 G P G P D P LR F G RG P P +G GPP P Sbjct: 1039 GDPGPAGLPGKDGPPG----------------LRGFPGDRGLPGPVGALGLKGNEGPPGP 1082 Query: 1056 PDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGR 1115 P G A GP G RPG P+ P P + +GA P +G Sbjct: 1083 PGPAGSPGERGPAGAAGPIGI--PGRPG----PQGPPGP--------AGEKGA-PGEKGP 1127 Query: 1116 APPRGRDGFPGPEDF--------GPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTP 1167 P GRDG GP P E+ D E G+ +G +G + PT Sbjct: 1128 QGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQ----KGSKGDKGEQGPPGPTG 1183 Query: 1168 DEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMAS 1227 + P + G P DG EPGP + + D P P L G Sbjct: 1184 PQGPIGQPG--PSGADG--EPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPG----- 1234 Query: 1228 LPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDG 1287 PP ++ G + P GP RG G G Q P + GE + Sbjct: 1235 -PPGEK------GETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEP 1287 Query: 1288 YHRDEP----FGGPPG-SGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 EP GGPPG G G SG + G GPP +G Sbjct: 1288 GEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336 Score = 251 bits (640), Expect = 4e-66 Identities = 246/749 (32%), Positives = 302/749 (40%), Gaps = 110/749 (14%) Query: 574 PPPSSGTPLLGPQPFPG----QGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPP 629 PP G LG PG QGP I GF + G PGP+GQ P Sbjct: 860 PPGEKGK--LGVPGLPGYPGRQGPKGSI--GFPGFPGANGEKGGRGTPGKPGPRGQRGPT 915 Query: 630 GPQGQMGPQG------PPLHQGGGGPQGFMGPQGPQGP--PQGLPRPQDMHGP---QGMQ 678 GP+G+ GP+G P + GG GP G G +GP GP P G P P+ GP G+ Sbjct: 916 GPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLP 975 Query: 679 RHPGPHGPLGPQG---PPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPP 735 HPG G G QG PPGP G GPQG G GP G +GH GP GPPG QG G G Sbjct: 976 GHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE 1035 Query: 736 GTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN-PRGMQGPPGPRENQ 794 GT+G GP G G GPP G++G PG +G+ GPV L G P G GP G + Sbjct: 1036 GTKGDPGPAGLPGKDGPP---GLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGER 1092 Query: 795 GPAPQGMIMGHP----PQEMRGPHPPGGLLGH-GPQEMRGPQEIRGMQGPPPQGSMLGPP 849 GPA +G P PQ GP G G GPQ G ++G G P +GPP Sbjct: 1093 GPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPP 1152 Query: 850 QE-----------LRGPPGSQSQQGPP-----QGSLGPPPQGGMQGPPGPQGQQNPARGP 893 E +G G + +QGPP QG +G P G G PGP+GQQ G Sbjct: 1153 GEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQG-LFGQ 1211 Query: 894 HPSQGPIPFQQQKTPLLGDGPRAPFNQEGQS-----TGPPPLIPGLGQQGAQGRIPPLNP 948 +GP F P+ G P ++G++ GPP G GA G P P Sbjct: 1212 KGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGP 1271 Query: 949 GQGPG-PNKGDSRGPPNHHMGPMSERRHEQSGGPEHGP--ERGPF--RGGQDCRGPPDRR 1003 G G P +G P G E GGP GP ERG G GPP + Sbjct: 1272 PGGIGNPGAVGEKGEP----GEAGEPGLPGEGGPP-GPKGERGEKGESGPSGAAGPPGPK 1326 Query: 1004 GPHPD-----------FPDDFSRPDDFHP---DKRFGHRLREFEG--------RGGPLPQ 1041 GP D FP D P + P D G + + E G P P Sbjct: 1327 GPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPS 1386 Query: 1042 EEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRRE 1101 +RG PGP P + G GPPG + G + P P RG Sbjct: 1387 GPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPG--KTGPIGPQGAPGKPGPDGLRGIPG 1444 Query: 1102 ESFRRGAP--PRHEGRAPPRGRDGFPGPE-DFGPEEN----------FDASEEAARG-RD 1147 +G P P +G P G G PG + D GP+ E+ +G R Sbjct: 1445 PVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRG 1504 Query: 1148 LRG-RGRGTPRG-----GRKGLLPTPDEFPRFEGGRKPDSWDGNREP-GP-GHEHFRDTP 1199 L G +G P+G G G + P P G P G+ P GP G P Sbjct: 1505 LPGPQGSSGPKGEQGITGPSGPIGPPGP-PGLPGPPGPKGAKGSSGPTGPKGEAGHPGPP 1563 Query: 1200 RPDHPPHDGHSPASRERSSSLQGMDMASL 1228 P PP + P + S + + +D + L Sbjct: 1564 GPPGPPGEVIQPLPIQASRTRRNIDASQL 1592 Score = 240 bits (613), Expect = 6e-63 Identities = 254/819 (31%), Positives = 317/819 (38%), Gaps = 117/819 (14%) Query: 574 PPPSSGTPLLGPQPFP--GQGPMSQIPQGFQQPHPSQQ-MPMNMAQMGPPGPQGQFRPPG 630 PP G + QP P GP + QQ +P Q +P +GPPG +G PG Sbjct: 692 PPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPG 751 Query: 631 PQGQMGPQGPPLHQGGGGPQGFMGPQGPQGP--PQGLPRPQDMHGPQGMQRHPGPHGPLG 688 G G GPP H G GP G G QGP GP P G P P+ + G G++ G G G Sbjct: 752 LPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKG 811 Query: 689 PQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPG---PQGHLGPQGPPGTQGM----- 740 G PG +G G +G G GPPGP+G GP+GP G P G GP GPPG +G Sbjct: 812 EDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPG 871 Query: 741 -------QGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ----GPLMGLNPRGMQGPPG 789 QGP G G G P +G +GG G+ G GP Q GP PRG+ G PG Sbjct: 872 LPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPG 931 Query: 790 PRENQG-PAPQGMIMGHPPQEMRGPHPPGGLLGH-GPQEMRGPQEIRGMQGPPPQGSMLG 847 P+ N G P G PP E RGP+ P G G GP+ GP G+ G P Q G Sbjct: 932 PKGNSGGDGPAG-----PPGE-RGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETG 985 Query: 848 PPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQN-----PARGPHPSQGPI 900 Q GPPG GP P G GP + G GPPGP G+Q G GP Sbjct: 986 F-QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPA 1044 Query: 901 PFQQQKTP-----LLGD----GPRAPFNQEGQS--TGPPPLIPGLGQQGAQGRIPPLNPG 949 + P GD GP +G GPP G++G G P+ Sbjct: 1045 GLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIP 1104 Query: 950 QGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDF 1009 PGP +GPP GP E+ GP+ R +G GP GP + Sbjct: 1105 GRPGP-----QGPP----GPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGE- 1154 Query: 1010 PDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGP----GPPFPPDHREFSEGD 1065 D + + P ++ + +G GP + + GP G P P + Sbjct: 1155 --DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQK 1212 Query: 1066 GRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFP 1125 G RG PG PG P P +G + + G PP G P G G Sbjct: 1213 GDEGPRGFPGP-----PGPVGLQGLPGPPGEKGETGDVGQMG-PPGPPGPRGPSGAPGAD 1266 Query: 1126 GPEDFGPEENF-DASEEAARGRDLRGRGRGTP-RGGRKGLLPTPDEFPRFEGGRKPDSWD 1183 GP+ GP + +G G P GG G P+ E G K +S Sbjct: 1267 GPQ--GPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG--------PKGERGEKGESGP 1316 Query: 1184 GNRE--PGP----GHEHFRDTPRP-----DHPPHDGHSPASRERSSSLQGMDMASLPPRK 1232 PGP G + + +P P D P PA ++ +G D Sbjct: 1317 SGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDD-------G 1369 Query: 1233 RPWHDG-PGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRD 1291 P G PG + P GP RG G GP Q + + L+G + Sbjct: 1370 EPGQTGSPGPTGE---PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPP----GKT 1422 Query: 1292 EPFG--GPPGSGTPS--RG--GRSGSNWGRGSNMNSGPP 1324 P G G PG P RG G G GS GPP Sbjct: 1423 GPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPP 1461 Score = 228 bits (580), Expect = 4e-59 Identities = 247/785 (31%), Positives = 301/785 (38%), Gaps = 121/785 (15%) Query: 592 GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQG----------PP 641 G + + P G + P P M G G G+ PPG G G G P Sbjct: 464 GMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLP 523 Query: 642 LHQGGGGPQGFMGPQGPQGPPQGLPRPQDMH-------GPQGMQRHPGPHGPLGPQGPPG 694 GGGG G GP Q Q GP G+ PGP GP G G G Sbjct: 524 FRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG 583 Query: 695 PQGSSGPQGHMGPQGPPGP------QGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRG 748 G GPQG G QGPPGP +G G G G G GP+G G G+ G PG +G Sbjct: 584 EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKG 643 Query: 749 MQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGP-APQGMIMGHPP 807 +G P P G G PG G +G + + PRG+ G PGPR GP P G PP Sbjct: 644 HRGDPGPSGPPGPPGDDGERGDDGE-----VGPRGLPGEPGPRGLLGPKGPPG--PPGPP 696 Query: 808 QEMRGPHPPGGLLGHGPQEMRGPQEIRGMQG----PPPQGSMLGPPQELRGPPGSQSQQG 863 PG GPQ GP +G G P PQG+ +GPP E +GP G G Sbjct: 697 GVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA-IGPPGE-KGPLGKPGLPG 754 Query: 864 PPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ 923 P G+ GPP G +GPPG +G Q GP QGPI + + DG R +G+ Sbjct: 755 MP-GADGPPGHPGKEGPPGEKGGQ----GPPGPQGPIGYPGPRGVKGADGIRGLKGTKGE 809 Query: 924 --STGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQS--- 978 G P +G +G +G I P P GP RG PN GP+ + Sbjct: 810 KGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGV 869 Query: 979 -GGPEHGPERGP-----FRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREF 1032 G P + +GP F G G RG P P + P G R Sbjct: 870 PGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGT-PGKPGPRGQRGPTGPRGERGP--RGI 926 Query: 1033 EGRGGPLPQEEKWRRGGPGPPFPPDHR--EFSEG-DGRGAARGPPGAWEGRRPGDERFPR 1089 G+ GP K GG GP PP R +G G +GPPG PG + P Sbjct: 927 TGKPGP-----KGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGP-----PGKDGLPG 976 Query: 1090 DPEDPRFRGRREESFRRG--APPRHEGRAPPRGRDGFPGP--EDFGPEENFDASEEAARG 1145 P G+R E+ +G PP G P+G G GP E P E+ G Sbjct: 977 HP------GQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPG 1030 Query: 1146 RDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNRE-PGP-GHEHFRDTPRPDH 1203 + +G P G G LP D P G + G+R PGP G + P Sbjct: 1031 LAGKEGTKGDP--GPAG-LPGKDGPPGLRG------FPGDRGLPGPVGALGLKGNEGPPG 1081 Query: 1204 PPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRG 1263 PP SP R + + P P GP + P GP+ ++G G Sbjct: 1082 PPGPAGSPGERGPA--------GAAGPIGIPGRPGP--------QGPPGPAGEKGAPGEK 1125 Query: 1264 GP-GPAQRVPKSGRSSSLDGEHHDGYHRDEPFG--GPPG-SGTPSRGGRSGSNWGRGSNM 1319 GP GPA R G L G P G GPPG G G G +G Sbjct: 1126 GPQGPAGRDGLQG-PVGLPG----------PAGPVGPPGEDGDKGEIGEPGQKGSKGDKG 1174 Query: 1320 NSGPP 1324 GPP Sbjct: 1175 EQGPP 1179 Score = 202 bits (514), Expect = 2e-51 Identities = 160/478 (33%), Positives = 195/478 (40%), Gaps = 92/478 (19%) Query: 584 GPQPFPGQ-GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPL 642 GP+ FPG GP+ QG P + ++ QMGPPGP G P G G GPQGPP Sbjct: 1216 GPRGFPGPPGPVGL--QGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPG 1273 Query: 643 ------------------------------------HQGGGGPQGFMGPQGPQGPPQGLP 666 +G GP G GP GP+GPP G Sbjct: 1274 GIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPP-GDD 1332 Query: 667 RPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQ 726 P+ GP G PGP G GP G GP G G G G G PGP G GP GPPG + Sbjct: 1333 GPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392 Query: 727 GHLGPQGPPGTQGMQGPPGPRGMQGPP---HPHGIQGGPGSQGIQGPVSQGPLMGLNPRG 783 G GP GP G QG +G G G++GPP P G QG PG G P G Sbjct: 1393 GPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG--------------PDG 1438 Query: 784 MQGPPGPRENQG----PAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGP 839 ++G PGP QG P P G PP M P PG GP+ +G + G+ GP Sbjct: 1439 LRGIPGPVGEQGLPGSPGPDG-----PPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGP 1493 Query: 840 PPQGSMLGP-----PQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPH 894 P + G PQ GP G Q G P G +GPP G+ GPPGP+G A+G Sbjct: 1494 PGEQGEKGDRGLPGPQGSSGPKGEQGITG-PSGPIGPPGPPGLPGPPGPKG----AKGSS 1548 Query: 895 PSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGP 954 GP K GP P G+ P P+ ++ G G Sbjct: 1549 GPTGP------KGEAGHPGPPGPPGPPGEVIQPLPIQASRTRRNIDA---SQLLDDGNGE 1599 Query: 955 NKGDSRGPPNHHMGPMSERRHE-QSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPD 1011 N D G ++ + E + G ++ P R C+ D + HPDFPD Sbjct: 1600 NYVDYADGMEEIFGSLNSLKLEIEQMKRPLGTQQNPAR---TCK---DLQLCHPDFPD 1651 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 249 bits (636), Expect = 1e-65 Identities = 256/816 (31%), Positives = 307/816 (37%), Gaps = 112/816 (13%) Query: 598 PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQG------GG---- 647 P+G P +P GPPGP G PPGP G G P L G GG Sbjct: 122 PRGPAGPPGRDGIPGQPGLPGPPGPPG---PPGPPGLGGNFAPQLSYGYDEKSTGGISVP 178 Query: 648 GPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGP 707 GP G GP+G GPP G P PQ GP G PG GP+GP+GPPGP G +G G G Sbjct: 179 GPMGPSGPRGLPGPP-GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGK 237 Query: 708 QGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGI 767 G PG +G GPQG G G G G G +G G G +G GP P G G PG G Sbjct: 238 PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297 Query: 768 QGPVSQGPLMGLNPR-GMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPG--GLLG--- 821 G + L G R G GP G R N G PP PPG G +G Sbjct: 298 PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAA----GPPGPTGPAGPPGFPGAVGAKG 353 Query: 822 ----HGPQEMRGPQEIRGMQGPPPQGSMLGPPQE--LRGPPGSQSQQGPP--------QG 867 GP+ GPQ +RG GPP GP G PG++ G P G Sbjct: 354 EAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPG 413 Query: 868 SLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQS--- 924 + GP G GPPGP+G P S+G + + P+ GP P +EG+ Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPG-SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472 Query: 925 --------TGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHE 976 GPP G G +G G P +GP +G S GP P R Sbjct: 473 GEPGPTGLPGPPGERGGPGSRGFPGADGVAGP-KGPAGERG-SPGPAGPKGSPGEAGRPG 530 Query: 977 QSG--------------GPEHGPERGPFRGGQDCR----GPPDRRGPHPDFPDDFSRPDD 1018 ++G GP+ G P GQD R GPP RG + Sbjct: 531 EAGLPGAKGLTGSPGSPGPD-GKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA 589 Query: 1019 FHPDKRFGHRLREFEGRGGPLPQE-EKWRRGGPGPPFPPDHR-----EFSEG-DGRGAAR 1071 P K + G GP ++ E +G PGP P R S G G Sbjct: 590 GEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA 649 Query: 1072 GPPGAWEGRRPGDERFPRD---PEDPRFRGRREESFRRGA--PPRHEGRAPPRGRDGFPG 1126 GPPG E +PG++ P D P RG R RG PP G A PRG +G PG Sbjct: 650 GPPG--EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP---GPAGPRGANGAPG 704 Query: 1127 PEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNR 1186 + DA A G +G P LP P G + D+ Sbjct: 705 NDG----AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPK-------GDRGDAGPKGA 753 Query: 1187 EPGPGHEHFRDTPRPDHPPHDGHSPASRERS--SSLQGMDMASLPPRKRPWHDGPGTSEH 1244 + PG + R P PP +P + S S G A P R PG + Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813 Query: 1245 REMEA----PGGPSE--DRGGKGRGGP-GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGP 1297 PG E D G KG GP GPA G ++ G GP Sbjct: 814 AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGS---AGP 870 Query: 1298 PGS-GTPSRGGRSGSNWGRGSNMNSGPPRRGASRGG 1332 PG+ G P GR G G+ GPP GG Sbjct: 871 PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906 Score = 242 bits (617), Expect = 2e-63 Identities = 238/713 (33%), Positives = 279/713 (39%), Gaps = 141/713 (19%) Query: 618 GPPGPQGQFRPPGPQGQ---MGPQGPPLHQGGGGPQGFMGPQGPQGPP-----QGLPRPQ 669 G PGP G+ PPGP GQ GP GPP +G G GF GP+G G P +G+P P Sbjct: 545 GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604 Query: 670 DMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQG-- 727 GP G G GP GP GP G +G GP G G QG PGP G G G PG QG Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVP 664 Query: 728 -HLGPQGPPGTQGMQGPPGPRGMQGPPHP---HGIQGGPGSQGIQG-------PVSQGP- 775 LG GP G +G +G PG RG+QGPP P G G PG+ G +G P SQG Sbjct: 665 GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724 Query: 776 -LMGL-NPRGMQGPPGPRENQGPAPQGMIMGHPPQE----MRGPHPPGGLLGH------- 822 L G+ RG G PGP+ ++G A G P ++ + GP P G G Sbjct: 725 GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGES 784 Query: 823 ------GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP--QGSLGPPPQ 874 GP RG RG GPP GPP G PG++ + G +G GPP Sbjct: 785 GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGA-DGQPGAKGEPGDAGAKGDAGPPGP 843 Query: 875 GGMQGPPGPQGQQNP--ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIP 932 G GPPGP G A+G S GP GP P G PP P Sbjct: 844 AGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAG-----PPGPP 898 Query: 933 G-LGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPER-GP- 989 G G++G +G P G P + GPP GP E+ + GP P GP Sbjct: 899 GPAGKEGGKG--PRGETGPAGRPGEVGPPGPP----GPAGEKGSPGADGPAGAPGTPGPQ 952 Query: 990 -FRGGQDCRGPPDRRGPH--PDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWR 1046 G + G P +RG P P P G+ GP Sbjct: 953 GIAGQRGVVGLPGQRGERGFPGLPGPSGEP-----------------GKQGP--SGASGE 993 Query: 1047 RGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRR--PGDERFPRDPEDPRFRGRREESF 1104 RG PGP PP GPPG GR PG E P P +G R E+ Sbjct: 994 RGPPGPMGPP------------GLAGPPGE-SGREGAPGAEGSPGRDGSPGAKGDRGET- 1039 Query: 1105 RRGAPPRHEGRAPPRGRDGFPG-PEDFGPEENFDASEEAARGRDLRGRGRGTPRG----- 1158 G A P G G PG P GP A + D G P G Sbjct: 1040 ---------GPAGPPGAPGAPGAPGPVGP---------AGKSGDRGETGPAGPAGPVGPV 1081 Query: 1159 GRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSS 1218 G +G P + PR + G + D + GH F P PP S Sbjct: 1082 GARG--PAGPQGPRGDKGETGEQGDRGIK---GHRGFSGLQGPPGPPG----------SP 1126 Query: 1219 SLQGMDMASLP--PRKRPWHDG-PGTSEHREMEAPGGPSEDRGGKGRGGP-GP 1267 QG AS P PR P G PG + P GP RG G GP GP Sbjct: 1127 GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGP 1179 Score = 240 bits (612), Expect = 8e-63 Identities = 252/814 (30%), Positives = 315/814 (38%), Gaps = 124/814 (15%) Query: 575 PPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG--- 630 P +G P +GP+ PG+ P P ++ GPPGP G PPG Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPG----PAGARGNDGATGAAGPPGPTGPAGPPGFPG 347 Query: 631 ---PQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPL 687 +G+ GPQGP +G GPQG G GP GP G P G G G +G Sbjct: 348 AVGAKGEAGPQGP---RGSEGPQGVRGEPGPPGPA-GAAGPAGNPGADGQPGAKGANGAP 403 Query: 688 GPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGP- 746 G G PG G+ GP G GP GPPGP+G+ G G PG +G G +G PG G+QGPPGP Sbjct: 404 GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463 Query: 747 -----RGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPA-PQG 800 RG +G P P G+ G PG +G GP S+G G +GP G R + GPA P+G Sbjct: 464 GEEGKRGARGEPGPTGLPGPPGERG--GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKG 521 Query: 801 MIMGHPPQEMRGPHPPG--GLLG-HGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPG 857 P E P G G G G GP G GP Q GPP GPPG Sbjct: 522 S-----PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP----GPPG 572 Query: 858 SQSQQGP-----PQGSLGPPPQGGMQGPPGPQGQQNPA--------RGPHPSQGPIPFQQ 904 ++ Q G P+G+ G P + G +G PGP G PA +GP GP + Sbjct: 573 ARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG 632 Query: 905 QKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPG----PNKGDSR 960 ++ P G F GPP G+QG G + P G P + + Sbjct: 633 EQGPAGSPG----FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688 Query: 961 GPPNHHMGPMSERR------HEQSGGPEHGPERGPFRGGQDCRGPPDRRG------PHPD 1008 GPP GP R ++ + G P +G +G P RG P D Sbjct: 689 GPP----GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGD 744 Query: 1009 FPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRG 1068 D + D P K L G GP GP P P + GD Sbjct: 745 RGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD--- 801 Query: 1069 AARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPE 1128 RG PG PG F P G + E GA +G A P G G GP Sbjct: 802 --RGEPGP-----PGPAGFAGPPGADGQPGAKGEPGDAGA----KGDAGPPGPAGPAGPP 850 Query: 1129 DFGPEENFDA-SEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNRE 1187 GP N A + ARG G P + P P G P +G + Sbjct: 851 --GPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908 Query: 1188 P----GP-GHEHFRDTPRPDHPPHDGHSP-----ASRERSSSLQGM----DMASLPPRK- 1232 P GP G P P P + SP A + QG+ + LP ++ Sbjct: 909 PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968 Query: 1233 -RPWHDGPGTSEHREMEAPGGPSEDRGGKG-RGGPGPAQRVPKSGRSSSLDGEHHDGYHR 1290 R + PG S + P G S +RG G G PG A +SGR Sbjct: 969 ERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGRE------------- 1015 Query: 1291 DEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 G P G+P R G G+ RG +GPP Sbjct: 1016 ----GAPGAEGSPGRDGSPGAKGDRGETGPAGPP 1045 Score = 239 bits (609), Expect = 2e-62 Identities = 273/899 (30%), Positives = 322/899 (35%), Gaps = 197/899 (21%) Query: 584 GPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQG------------------Q 625 GP+ PG P + PQGFQ P P MGP GP G + Sbjct: 185 GPRGLPGP-PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE 243 Query: 626 FRPPGPQG---------------------------QMGPQGPPLHQGGGGPQGFMGPQGP 658 PPGPQG GP GP G G G G GP Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303 Query: 659 QGPP-----QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPG---------------PQGS 698 +G P G P P G G GP GP GP GPPG P+GS Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363 Query: 699 SGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP---------PGTQGMQGPPGPRGM 749 GPQG G GPPGP G GP G PG G G +G PG G +GP GP+G Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG-------PAPQGMI 802 GPP P G G PG+ G +G G P G+QGPPGP +G P P G+ Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPG--PVGVQGPPGPAGEEGKRGARGEPGPTGL- 480 Query: 803 MGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP-PQGSM--LGPPQELRGPPGSQ 859 PP E GP G G +GP RG GP P+GS G P E G PG++ Sbjct: 481 -PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA-GLPGAK 538 Query: 860 SQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLG-DGPRAPF 918 G P G P G GPPGP GQ P P P + + ++G GP+ Sbjct: 539 GLTGSP----GSPGPDGKTGPPGPAGQDGRPGPPGP-----PGARGQAGVMGFPGPKGAA 589 Query: 919 NQEGQS-----TGPPPLIPGLGQQG---AQGRIPPLNPG-----QGPGPNKG-----DSR 960 + G++ GPP + G+ G AQG P P QGP + G Sbjct: 590 GEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA 649 Query: 961 GPPNHHMGPMSERRHEQSGGPEHGPERGP--FRGGQDCRGPPDRRGPHP--DFPDDFSRP 1016 GPP P + G P RG F G + +GPP GP P + Sbjct: 650 GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAK 709 Query: 1017 DDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHR-----EFSEGD-GRGAA 1070 D G +G P Q RG G P P R + ++G G+ Sbjct: 710 GDAGAPGAPG-------SQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGV 762 Query: 1071 RG------PPGAWEGRRPGD--ERFPRDPEDPRFRGRREESFRRG--APPRHEGRAPPRG 1120 RG PPG PGD E P P P G R RG PP G A P G Sbjct: 763 RGLTGPIGPPGP--AGAPGDKGESGPSGPAGPT--GARGAPGDRGEPGPPGPAGFAGPPG 818 Query: 1121 RDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRG-----GRKGLL-----PTPDEF 1170 DG PG + G + A +A G P G G KG P F Sbjct: 819 ADGQPGAK--GEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGF 876 Query: 1171 PRFEGGRKPDSWDGNR----EPGPGHEHFRDTPR-------------PDHPPHDGHSPAS 1213 P G P GN PGP + PR P PP PA Sbjct: 877 PGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP----GPAG 932 Query: 1214 RERSSSLQGMDMASLPPRKRPWHDGP-GTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVP 1272 + S G P P GP G + R + G +RG G PGP+ Sbjct: 933 EKGSPGADG-------PAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL--PGPSGEPG 983 Query: 1273 KSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 K G S + G P G P +G P GR G+ GS G P RG Sbjct: 984 KQGPSGASGERGPPG-----PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRG 1037 Score = 237 bits (604), Expect = 6e-62 Identities = 252/814 (30%), Positives = 302/814 (37%), Gaps = 154/814 (18%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----------QGLP 666 GP GPQG PPGP+G G G P +G G +G GP G QGPP +G P Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475 Query: 667 RPQDMHGPQGMQRHPG------------PHGPLGPQGPPGP---QGSSGPQGHMGPQGPP 711 P + GP G + PG P GP G +G PGP +GS G G G G P Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 712 GPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGP------PHPHGIQGGPGSQ 765 G +G G G PGP G GP GP G G GPPGP G +G P P G G PG Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 766 GIQG----PVSQGPLMGLNPRGMQGPPGP------RENQGPAPQGMIMG-----HPPQEM 810 G +G P + GP G QGPPGP R QGPA G PP E Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655 Query: 811 RGPHP---PGGLLGHGPQEMRGPQEI---RGMQGPP----PQGSMLGPPQELR----GPP 856 P PG L GP RG + RG+QGPP P+G+ P + G P Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAP 715 Query: 857 GSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPA--RGPHPSQGPIPFQQQKTPLLGDGP 914 G+ QG P G G P + G G PGP+G + A +G S G + P+ GP Sbjct: 716 GAPGSQGAP-GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGP 774 Query: 915 RAPFNQEGQS--TGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSE 972 +G+S +GP G G +G P P GP D G P P Sbjct: 775 AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGAD--GQPGAKGEPGDA 832 Query: 973 RRHEQSGGPEHGPERGP-----------FRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHP 1021 +G P GP +G + GPP G FP R Sbjct: 833 GAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG----FPGAAGRV----- 883 Query: 1022 DKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRR 1081 G P P G GPP PP G G GP G R Sbjct: 884 --------------GPPGPS------GNAGPPGPPGPAGKEGGKGPRGETGPAG-----R 918 Query: 1082 PGDERFPRDPEDPRFRGRREESFRRGAP--PRHEGRAPPRGRDGFPGP--EDFGPEENFD 1137 PG+ P P +G GAP P +G A RG G PG E P Sbjct: 919 PGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGP 978 Query: 1138 ASEEAARGRDLRGRGRGTPRG-GRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFR 1196 + E +G RG P G GL P E R EG + G R+ PG + R Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGR-EGAPGAEGSPG-RDGSPGAKGDR 1036 Query: 1197 DTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGP-GTSEHREMEAPGGPSE 1255 P PP +P + P GP G S R P GP+ Sbjct: 1037 GETGPAGPPGAPGAPGA--------------------PGPVGPAGKSGDRGETGPAGPAG 1076 Query: 1256 DRGGKGRGGP----GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS-GTPSRGGRSG 1310 G G GP GP ++G + H G+ + GPPGS G G SG Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG 1136 Query: 1311 SNWGRGSNMNSGPPRRGASRG--------GGRGR 1336 RG ++G P + G G RGR Sbjct: 1137 PAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170 Score = 208 bits (530), Expect = 2e-53 Identities = 195/585 (33%), Positives = 234/585 (40%), Gaps = 76/585 (12%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMN---MAQMGPPGPQGQFRPPG 630 P PS G + FPG+ + Q P G P + P N G PG G PG Sbjct: 670 PGPSGAR---GERGFPGERGV-QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG 725 Query: 631 PQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----QGLPRPQDMHGPQGMQRHPGPHG 685 QG G +G G G +G GP+G G P +GL P GP G PG G Sbjct: 726 LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA---PGDKG 782 Query: 686 PLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPG 745 GP GP GP G+ G G G GPPGP G GP G G G G G G +G GPPG Sbjct: 783 ESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPG 842 Query: 746 PRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGL-NPRGMQGPPGPRENQG----PAPQG 800 P G GPP P G G PG++G +G G G GPPGP N G P P G Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAG 902 Query: 801 MIMGHPPQEMRGP-HPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGP-----PQELRG 854 G P+ GP PG + GP G + G GP GP + + G Sbjct: 903 KEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVG 962 Query: 855 PPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGP 914 PG + ++G P G GP + G QGP G G+ RGP GP P L GP Sbjct: 963 LPGQRGERGFP-GLPGPSGEPGKQGPSGASGE----RGPPGPMGP--------PGLA-GP 1008 Query: 915 RAPFNQEGQ--STGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSE 972 +EG + G P G +G +G P P PG + G P +GP + Sbjct: 1009 PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPG-----APGAPG-PVGPAGK 1062 Query: 973 RRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREF 1032 GP GP GP G RGP +GP D + + D GH R F Sbjct: 1063 SGDRGETGPA-GP-AGPV-GPVGARGPAGPQGPRGDKGETGEQGDRGIK----GH--RGF 1113 Query: 1033 EGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPG-AWEGRRPGDERFPRDP 1091 G GP PGPP P + S G RGPPG A + G P Sbjct: 1114 SGLQGP-----------PGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPI 1162 Query: 1092 EDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENF 1136 P RGR ++ G P P G G PGP G + +F Sbjct: 1163 GPPGPRGRTGDAGPVGPP-------GPPGPPGPPGPPSAGFDFSF 1200 Score = 151 bits (382), Expect = 4e-36 Identities = 102/269 (37%), Positives = 119/269 (44%), Gaps = 36/269 (13%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIP-----QGFQ-----QPHPSQQMPMNMA-QMGPPGP 622 P + GTP GPQ GQ + +P +GF P +Q P + + GPPGP Sbjct: 942 PAGAPGTP--GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGP 999 Query: 623 QGQFRPPGPQGQMG------PQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQG 676 G GP G+ G +G P G G +G G GP GPP G P GP G Sbjct: 1000 MGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPP-GAPGAPGAPGPVG 1058 Query: 677 MQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG------ 730 G G GP GP GP G G +G GPQGP G +G G QG G +GH G Sbjct: 1059 PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQG 1118 Query: 731 PQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-------PVSQGPLMGLNPRG 783 P GPPG+ G QGP G G GP P G G PG G+ G P +G P G Sbjct: 1119 PPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVG 1178 Query: 784 MQGPPGPRENQGPAPQGM---IMGHPPQE 809 GPPGP GP G + PPQE Sbjct: 1179 PPGPPGPPGPPGPPSAGFDFSFLPQPPQE 1207 Score = 91.3 bits (225), Expect = 6e-18 Identities = 137/503 (27%), Positives = 161/503 (32%), Gaps = 112/503 (22%) Query: 841 PQGSMLGPPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQG 898 P GS QE G G + GP P+G GPP + G+ G PG G P P P Sbjct: 96 PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGP--- 152 Query: 899 PIPFQQQKTPLLGDG--PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNK 956 P LG P+ + + +STG G+ G G P P PGP Sbjct: 153 ---------PGLGGNFAPQLSYGYDEKSTG------GISVPGPMG---PSGPRGLPGPPG 194 Query: 957 GDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRP 1016 P GP E + GP GP RGP GPP + G DD Sbjct: 195 APG---PQGFQGPPGEPGEPGASGPM-GP-RGP-------PGPPGKNG------DDGEAG 236 Query: 1017 DDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGA 1076 P +R G P PQ + G G P HR FS DG GP G Sbjct: 237 KPGRPGER-----------GPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGP 285 Query: 1077 WEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENF 1136 +P P G + RG P RGR G PGP Sbjct: 286 -----------KGEPGSPGENGAPGQMGPRGLPGE-------RGRPGAPGPA-------- 319 Query: 1137 DASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEG--GRKPDSWDGNREPGPGHEH 1194 ARG D G P G G P P F G G K ++ G + Sbjct: 320 -----GARGNDGATGAAGPP--GPTG----PAGPPGFPGAVGAKGEAGPQGPRGSEGPQG 368 Query: 1195 FRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPS 1254 R P P P PA + G A+ P PG + PGGP Sbjct: 369 VRGEPGPPGPA-GAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPP 427 Query: 1255 EDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG-SGTPSRGGRSGSNW 1313 +G G G G D + EP GP G G P G G Sbjct: 428 GPKGNSGEPGA---------------PGSKGDTGAKGEP--GPVGVQGPPGPAGEEGKRG 470 Query: 1314 GRGSNMNSGPPRRGASRGGGRGR 1336 RG +G P RGG R Sbjct: 471 ARGEPGPTGLPGPPGERGGPGSR 493 Score = 51.2 bits (121), Expect = 7e-06 Identities = 41/105 (39%), Positives = 46/105 (43%), Gaps = 24/105 (22%) Query: 572 IQPPPSSGTPLLGPQPFPG-QGPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPP 629 +Q PP GP PG QGP P G + P S P G PGP G PP Sbjct: 1116 LQGPP-------GPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIG---PP 1165 Query: 630 GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQG------LPRP 668 GP+G+ G GP GP G GP GP GPP LP+P Sbjct: 1166 GPRGRTGDAGPV------GPPGPPGPPGPPGPPSAGFDFSFLPQP 1204 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 248 bits (633), Expect = 3e-65 Identities = 256/810 (31%), Positives = 307/810 (37%), Gaps = 137/810 (16%) Query: 569 VEQIQPPPSSGTPLLGPQPFPGQ--------GPMSQIPQGFQQPHPSQQMPMNMAQMGPP 620 V I PP G P G + FPGQ P + P G P + P + G P Sbjct: 500 VGPIGPPGERGAP--GNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 557 Query: 621 GPQGQFRPPG---PQGQMGPQGPPLHQGGGGP------------QGFMGPQGPQGPPQGL 665 G +G PG PQG++GP G P G GP GF GP+G G P G Sbjct: 558 GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP-GK 616 Query: 666 PRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGP 725 + + G G++ PG G G GPPGP G +G +G G GP G QG GP GPPG Sbjct: 617 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 676 Query: 726 QGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN-PRGM 784 G G QG PG G G GPRG +G P G +G PG+QG+QGP G + P+G Sbjct: 677 GGKPGDQGVPGEAGAPGLVGPRGERGFP---GERGSPGAQGLQGPRGLPGTPGTDGPKGA 733 Query: 785 QGPPGPRENQGPAP-QGMIMGHPPQEMRGPHPPGGLLGH-GPQEMRGPQEIRGMQGP--P 840 GP GP QGP QGM + GP G +G GP+ G RG+ GP P Sbjct: 734 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 793 Query: 841 P-------QGSMLGPPQELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPA- 890 P + +GPP GP GS +G P +G GPP G GPPG GQ Sbjct: 794 PGPAGANGEKGEVGPP----GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 849 Query: 891 -RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ-----STGPPPLIPGLGQQGAQGRIP 944 +G +G + P GP+ P G + GPP G GA GR+ Sbjct: 850 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG---ATGFPGAAGRVG 906 Query: 945 PLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRG 1004 P PGP GPP GP + + + G P R G Q GPP +G Sbjct: 907 PPGSNGNPGPP-----GPP----GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957 Query: 1005 -PHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSE 1063 P D P P P G R G G LP + + RG PG P P Sbjct: 958 EPGDDGPSGAEGPPG--PQGLAGQR-----GIVG-LPGQ-RGERGFPGLPGPSGEPGKQG 1008 Query: 1064 GDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDG 1123 G RGPPG P P P G E R G+P G P GRDG Sbjct: 1009 APGASGDRGPPG------------PVGP--PGLTGPAGEPGREGSP----GADGPPGRDG 1050 Query: 1124 FPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWD 1183 G + D E A G G P G PT + R E G + Sbjct: 1051 AAGVKG-------DRGETGAVGAP----GAPGPPGSPGPAGPTGKQGDRGEAGAQ----- 1094 Query: 1184 GNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSE 1243 G P G R P P D P +R G + Sbjct: 1095 GPMGPS-GPAGARGIQGPQGPRGDKGEAGE----------------PGERGLKGHRGFTG 1137 Query: 1244 HREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTP 1303 + + P GPS D+G G GP + P S DG + G P G P Sbjct: 1138 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGAN----------GIPGPIGPP 1187 Query: 1304 SRGGRSGSNWGRGSNMNSGPPRRGASRGGG 1333 GRSG G N GPP G G Sbjct: 1188 GPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1217 Score = 245 bits (625), Expect = 2e-64 Identities = 275/898 (30%), Positives = 335/898 (37%), Gaps = 234/898 (26%) Query: 618 GPPGPQGQFR-------------PPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-- 662 G PGP+GQ PPGPQG G QGP +G G +G GP+G G P Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157 Query: 663 ---QGLPRPQDMHGPQGMQRH---------------------PGPHGPLGPQGPPGPQGS 698 G P P GP G+ + GP GP+GP+GPPGP G+ Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217 Query: 699 SGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGI 758 GPQG G G PG G GP GP GP GP G PG G G PG G +GPP P G Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPP---GPPGKPGDDGEAGKPGKAGERGPPGPQGA 274 Query: 759 QGGPGSQGIQGPVSQGPLMGLN-PRGMQGPPG-------PRENQGPAPQGMIMGHPPQEM 810 +G PG+ G+ G GL+ +G G PG P EN P P G G P + Sbjct: 275 RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP-RGLPGE-- 331 Query: 811 RGPHPPGGLLGHGPQEMRGPQEIRGMQGPP-PQGSMLGPPQELRGPPGSQSQQGP----- 864 RG P G G RG G GPP P G GP G PG++ + GP Sbjct: 332 RGRTGPAGAAG-----ARGNDGQPGPAGPPGPVGPAGGP--GFPGAPGAKGEAGPTGARG 384 Query: 865 PQGSLGPPPQGGMQGPPGPQGQQ-NPARGPHPS----------QGPIPFQQQKTPLLGDG 913 P+G+ GP + G G PGP G NP P G F + P G Sbjct: 385 PEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444 Query: 914 PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGP----NKGDSRGPPN--HHM 967 P +GQ TG P + G+QG +G P P PGP K +RG P + Sbjct: 445 ATGPLGPKGQ-TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503 Query: 968 GPMSER---------RHEQSGGPEHGP-ERGP--FRGGQDCRGPPDRRGPHPDFPDD--- 1012 GP ER + GP+ P ERGP G + G P R G P P Sbjct: 504 GPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG-EPGLPGARGL 562 Query: 1013 FSRPDDFHPDKRFGHRLREFE-GRGGPL-PQEEKWR---RGGPGP--------------- 1052 RP D P + G E GR GP PQ + + G PGP Sbjct: 563 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 622 Query: 1053 PFPPDHREFSEGDGRGAARGPPG----------------------------AWEGRRPGD 1084 P P R DG A GPPG EG +PGD Sbjct: 623 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 682 Query: 1085 ERFPRDPEDPRFRGRREESFRRGAP-----PRHEGRAPPRGRDGFPGPEDFGPE-ENFDA 1138 + P + P G R E RG P P +G PRG G PG + GP+ + A Sbjct: 683 QGVPGEAGAPGLVGPRGE---RGFPGERGSPGAQGLQGPRGLPGTPGTD--GPKGASGPA 737 Query: 1139 SEEAARG-RDLRG-------RGRGTPRG-----GRKGLLPTPDEFPRFEGGR-------K 1178 A+G L+G G P+G G KG P+ P +GGR Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG----PEGAPGKDGGRGLTGPIGP 793 Query: 1179 PDSWDGNREPG----------------PGHEHFRDTPRP----DHPPHDGHSPASRERSS 1218 P N E G PG P P P DG A E+ Sbjct: 794 PGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGE 853 Query: 1219 SLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVP-KSGRS 1277 + Q D + P+ GP + P G + +G +G GP A P +GR Sbjct: 854 AGQKGDAGAPGPQGPSGAPGP--------QGPTGVTGPKGARGAQGPPGATGFPGAAGRV 905 Query: 1278 SSLDGEHHDGYHRDEPFGGPPGS----GTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 GPPGS G P G SG + +G+ +SGPP R G Sbjct: 906 ------------------GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPG 945 Score = 236 bits (601), Expect = 1e-61 Identities = 271/905 (29%), Positives = 335/905 (37%), Gaps = 169/905 (18%) Query: 575 PPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 P +G+P +GP+ PG+ +G P + N Q GP GP G P GP G Sbjct: 314 PGENGSPGPMGPRGLPGE-------RGRTGPAGAAGARGNDGQPGPAGPPG---PVGPAG 363 Query: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPP 693 G G P +G GP G GP+G QGP +G P GP G +PG G G +G Sbjct: 364 GPGFPGAPGAKGEAGPTGARGPEGAQGP-RGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 422 Query: 694 GPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGP---------QGHLGPQGPPGTQGMQGPP 744 G G +G G GP+GPPGPQG GP GP G +G GP+G PG G QG P Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 482 Query: 745 GPRGMQ------------GPPHPHGIQGGPGSQGIQG----------PVSQGPLMGLNPR 782 GP G + GP P G +G PG++G G P +GP P+ Sbjct: 483 GPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK 542 Query: 783 GMQGPPG-PRENQGPAPQGMIMGHP----PQEMRGPHPPGGLLGH----GPQEMRGPQEI 833 G G PG P E P +G + G P PQ GP G G GPQ RG + Sbjct: 543 GANGDPGRPGEPGLPGARG-LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 601 Query: 834 RGMQGP------PPQGSMLGPP--QELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGP 883 G GP P + G P LRG PG + G P G GP + G QG PGP Sbjct: 602 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 661 Query: 884 QGQQN-------PARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGP-----PPLI 931 G Q P G P +P + L+G F E S G P + Sbjct: 662 SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 721 Query: 932 PGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHH-----MGPMSERRHEQSGGPEHGP 985 PG G G +G P P GP +G P GP +R GPE P Sbjct: 722 PGTPGTDGPKGASGPAGPPGAQGP--PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP 779 Query: 986 ER-------GPF--------------------RGGQDCRGPPDRRG-PHPDFPDDFSRPD 1017 + GP G RG P RG P P F+ P Sbjct: 780 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839 Query: 1018 DFHPDKRFGHRLREFEG-----RGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARG 1072 D + G + + E G P PQ G PGP P + G A+G Sbjct: 840 G--ADGQPGAKGEQGEAGQKGDAGAPGPQGPS---GAPGPQGPTG---VTGPKGARGAQG 891 Query: 1073 PPGAW-----EGR--RPGDERFPRDPEDPRFRGRREESFRRG--------APPRHEGRAP 1117 PPGA GR PG P P P G+ RG P +G A Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 951 Query: 1118 PRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGR 1177 P G G PG + E + A R + G G G LP P P +G Sbjct: 952 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG-LPGPSGEPGKQGA- 1009 Query: 1178 KPDSWDGNREPGP----------GHEHFRDTPRPDHPP-HDGHSPASRER-SSSLQGMDM 1225 P + PGP G +P D PP DG + +R + G Sbjct: 1010 -PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPG 1068 Query: 1226 ASLPPRKRPWHDGP----GTSEHREMEAPGGPSEDRGGKGRGGP-GPAQRVPKSGRSSSL 1280 A PP P GP G + P GPS G +G GP GP ++G Sbjct: 1069 APGPPGS-PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1127 Query: 1281 DGEHHDGYHRDEPFGGPPG-SGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG-------- 1331 + H G+ + GPPG SG G +G + RG GP + + G Sbjct: 1128 GLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1187 Query: 1332 GGRGR 1336 G RGR Sbjct: 1188 GPRGR 1192 Score = 226 bits (575), Expect = 1e-58 Identities = 202/610 (33%), Positives = 245/610 (40%), Gaps = 94/610 (15%) Query: 565 AQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQG 624 A ++ EQ P PS L GP PG+G QG + + + G PG +G Sbjct: 650 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG-DQGVPGEAGAPGLVGPRGERGFPGERG 708 Query: 625 QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP---QGPP--QGLPRPQDMHGPQGMQR 679 PG QG GP+G P G GP+G GP GP QGPP QG+P + G G + Sbjct: 709 S---PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 765 Query: 680 HPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG 739 G G GP+G PG G G G +GP GP G G G GPPGP G G +G PG +G Sbjct: 766 DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 825 Query: 740 MQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG-PAP 798 GPPGP G GPP G G PG++G QG Q +G G PGP+ G P P Sbjct: 826 ETGPPGPAGFAGPP---GADGQPGAKGEQGEAGQ--------KGDAGAPGPQGPSGAPGP 874 Query: 799 QGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGS 858 QG P + GP G GP G G GPP GPP GPPG Sbjct: 875 QG------PTGVTGPKGARG--AQGPPGATGFPGAAGRVGPPGSNGNPGPP----GPPGP 922 Query: 859 QSQQGP--PQGSLGPPPQG---GMQGPPGPQGQQNPA--RGPHPSQGPIPFQQQKTPLLG 911 + GP +G GPP + G+QGP GP G++ GP ++GP Sbjct: 923 SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP------------ 970 Query: 912 DGPRAPFNQEGQSTGPPPLIPGL-GQQGAQG----RIPPLNPGQGPGPNKGDSRGPPN-- 964 GP+ Q G I GL GQ+G +G P PG+ P RGPP Sbjct: 971 PGPQGLAGQRG--------IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022 Query: 965 ---HHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHP 1021 GP E E S G + P R G + RG G P P P P Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA-PGAPGPPGSPGPAGP 1081 Query: 1022 DKRFGHRLREFEGRGGPL----------------PQEEKWRRGGPGPPFPPDHREFSEGD 1065 + G R G GP+ P+ +K G PG HR F+ Sbjct: 1082 TGKQGDRGE--AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1139 Query: 1066 GRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFP 1125 G GP G P PR P P ++ + P G PRGR G Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA---NGIPGPIGPPGPRGRSGET 1196 Query: 1126 GPEDFGPEEN 1135 GP GP N Sbjct: 1197 GPA--GPPGN 1204 Score = 192 bits (488), Expect = 2e-48 Identities = 145/394 (36%), Positives = 171/394 (43%), Gaps = 61/394 (15%) Query: 574 PPPSSGTPLLGPQ-PFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632 P SG P GPQ P GP +G Q P + P ++GPPG G PPGP Sbjct: 865 PQGPSGAP--GPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP 920 Query: 633 GQMGPQGPPLHQGGGGPQGFMGP---QGPQGPP--------------QGLPRPQDMHGPQ 675 G G GP +G GP G G QGP GPP +G P PQ + G + Sbjct: 921 GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 980 Query: 676 GMQRHPGPHGPLG------PQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHL 729 G+ PG G G P G PG QG+ G G GP GP GP G GP G PG +G Sbjct: 981 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 1040 Query: 730 GPQGPPGTQGMQG---------------PPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQG 774 G GPPG G G PGP G GP P G QG G G QGP+ G Sbjct: 1041 GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPM--G 1098 Query: 775 PLMGLNPRGMQGPPGPRENQG----PAPQGMIMGHPP----QEMRGPHPPGGLLG-HGPQ 825 P RG+QGP GPR ++G P +G+ GH Q + GP P G G GP Sbjct: 1099 PSGPAGARGIQGPQGPRGDKGEAGEPGERGL-KGHRGFTGLQGLPGPPGPSGDQGASGPA 1157 Query: 826 EMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG 885 GP+ G GP + G P + GPPG + + G G GPP G GPPGP G Sbjct: 1158 GPSGPRGPPGPVGPSGKDGANGIPGPI-GPPGPRGRSGET-GPAGPPGNPGPPGPPGPPG 1215 Query: 886 ---QQNPARGPHP-SQGPIPFQQQKTPLLGDGPR 915 + G P +GP P Q + G R Sbjct: 1216 PGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLR 1249 Score = 140 bits (354), Expect = 6e-33 Identities = 99/252 (39%), Positives = 109/252 (43%), Gaps = 21/252 (8%) Query: 574 PPPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632 PP G P L GP PG+ + G P G G G PGP Sbjct: 1018 PPGPVGPPGLTGPAGEPGR----EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPP 1073 Query: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQ 690 G GP GP QG G G GP GP GP +G+ PQ G +G PG G G + Sbjct: 1074 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1133 Query: 691 GPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQ 750 G G QG GP G G QG GP G GP+GPPGP G G G G G GPPGPRG Sbjct: 1134 GFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRS 1193 Query: 751 GPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEM 810 G P G G PG G GP P G++ G GPRE +GP P Q M Sbjct: 1194 GETGPAGPPGNPGPPGPPGP----PGPGIDMSAFAG-LGPRE-KGP--------DPLQYM 1239 Query: 811 RGPHPPGGLLGH 822 R GGL H Sbjct: 1240 RADQAAGGLRQH 1251 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 248 bits (633), Expect = 3e-65 Identities = 256/810 (31%), Positives = 307/810 (37%), Gaps = 137/810 (16%) Query: 569 VEQIQPPPSSGTPLLGPQPFPGQ--------GPMSQIPQGFQQPHPSQQMPMNMAQMGPP 620 V I PP G P G + FPGQ P + P G P + P + G P Sbjct: 431 VGPIGPPGERGAP--GNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 488 Query: 621 GPQGQFRPPG---PQGQMGPQGPPLHQGGGGP------------QGFMGPQGPQGPPQGL 665 G +G PG PQG++GP G P G GP GF GP+G G P G Sbjct: 489 GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP-GK 547 Query: 666 PRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGP 725 + + G G++ PG G G GPPGP G +G +G G GP G QG GP GPPG Sbjct: 548 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 607 Query: 726 QGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN-PRGM 784 G G QG PG G G GPRG +G P G +G PG+QG+QGP G + P+G Sbjct: 608 GGKPGDQGVPGEAGAPGLVGPRGERGFP---GERGSPGAQGLQGPRGLPGTPGTDGPKGA 664 Query: 785 QGPPGPRENQGPAP-QGMIMGHPPQEMRGPHPPGGLLGH-GPQEMRGPQEIRGMQGP--P 840 GP GP QGP QGM + GP G +G GP+ G RG+ GP P Sbjct: 665 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 724 Query: 841 P-------QGSMLGPPQELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPA- 890 P + +GPP GP GS +G P +G GPP G GPPG GQ Sbjct: 725 PGPAGANGEKGEVGPP----GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 780 Query: 891 -RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ-----STGPPPLIPGLGQQGAQGRIP 944 +G +G + P GP+ P G + GPP G GA GR+ Sbjct: 781 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG---ATGFPGAAGRVG 837 Query: 945 PLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRG 1004 P PGP GPP GP + + + G P R G Q GPP +G Sbjct: 838 PPGSNGNPGPP-----GPP----GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888 Query: 1005 -PHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSE 1063 P D P P P G R G G LP + + RG PG P P Sbjct: 889 EPGDDGPSGAEGPPG--PQGLAGQR-----GIVG-LPGQ-RGERGFPGLPGPSGEPGKQG 939 Query: 1064 GDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDG 1123 G RGPPG P P P G E R G+P G P GRDG Sbjct: 940 APGASGDRGPPG------------PVGP--PGLTGPAGEPGREGSP----GADGPPGRDG 981 Query: 1124 FPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWD 1183 G + D E A G G P G PT + R E G + Sbjct: 982 AAGVKG-------DRGETGAVGAP----GAPGPPGSPGPAGPTGKQGDRGEAGAQ----- 1025 Query: 1184 GNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSE 1243 G P G R P P D P +R G + Sbjct: 1026 GPMGPS-GPAGARGIQGPQGPRGDKGEAGE----------------PGERGLKGHRGFTG 1068 Query: 1244 HREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTP 1303 + + P GPS D+G G GP + P S DG + G P G P Sbjct: 1069 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGAN----------GIPGPIGPP 1118 Query: 1304 SRGGRSGSNWGRGSNMNSGPPRRGASRGGG 1333 GRSG G N GPP G G Sbjct: 1119 GPRGRSGETGPAGPPGNPGPPGPPGPPGPG 1148 Score = 245 bits (625), Expect = 2e-64 Identities = 277/904 (30%), Positives = 338/904 (37%), Gaps = 224/904 (24%) Query: 599 QGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP 658 Q +QP P Q GP+G PPGPQG G QGP +G G +G GP+G Sbjct: 26 QDVRQPGPKGQKGEPGDIKDIVGPKG---PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGR 82 Query: 659 QGPP-----QGLPRPQDMHGPQGMQRH---------------------PGPHGPLGPQGP 692 G P G P P GP G+ + GP GP+GP+GP Sbjct: 83 DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 142 Query: 693 PGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGP 752 PGP G+ GPQG G G PG G GP GP GP GP G PG G G PG G +GP Sbjct: 143 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPP---GPPGKPGDDGEAGKPGKAGERGP 199 Query: 753 PHPHGIQGGPGSQGIQGPVSQGPLMGLN-PRGMQGPPG-------PRENQGPAPQGMIMG 804 P P G +G PG+ G+ G GL+ +G G PG P EN P P G G Sbjct: 200 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP-RG 258 Query: 805 HPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP-PQGSMLGPPQELRGPPGSQSQQG 863 P + RG P G G RG G GPP P G GP G PG++ + G Sbjct: 259 LPGE--RGRTGPAGAAG-----ARGNDGQPGPAGPPGPVGPAGGP--GFPGAPGAKGEAG 309 Query: 864 P-----PQGSLGPPPQGGMQGPPGPQGQQ-NPARGPHPS----------QGPIPFQQQKT 907 P P+G+ GP + G G PGP G NP P G F + Sbjct: 310 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369 Query: 908 PLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGP----NKGDSRGPP 963 P G P +GQ TG P + G+QG +G P P PGP K +RG P Sbjct: 370 PPGPQGATGPLGPKGQ-TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 428 Query: 964 N--HHMGPMSER---------RHEQSGGPEHGP-ERGP--FRGGQDCRGPPDRRGPHPDF 1009 +GP ER + GP+ P ERGP G + G P R G P Sbjct: 429 GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG-EPGL 487 Query: 1010 PDD---FSRPDDFHPDKRFGHRLREFE-GRGGPL-PQEEKWR---RGGPGP--------- 1052 P RP D P + G E GR GP PQ + + G PGP Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 547 Query: 1053 ------PFPPDHREFSEGDGRGAARGPPG----------------------------AWE 1078 P P R DG A GPPG E Sbjct: 548 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 607 Query: 1079 GRRPGDERFPRDPEDPRFRGRREESFRRGAP-----PRHEGRAPPRGRDGFPGPEDFGPE 1133 G +PGD+ P + P G R E RG P P +G PRG G PG + GP+ Sbjct: 608 GGKPGDQGVPGEAGAPGLVGPRGE---RGFPGERGSPGAQGLQGPRGLPGTPGTD--GPK 662 Query: 1134 -ENFDASEEAARG-RDLRG-------RGRGTPRG-----GRKGLLPTPDEFPRFEGGR-- 1177 + A A+G L+G G P+G G KG P+ P +GGR Sbjct: 663 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG----PEGAPGKDGGRGL 718 Query: 1178 -----KPDSWDGNREPG----------------PGHEHFRDTPRP----DHPPHDGHSPA 1212 P N E G PG P P P DG A Sbjct: 719 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 778 Query: 1213 SRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVP 1272 E+ + Q D + P+ GP + P G + +G +G GP A P Sbjct: 779 KGEQGEAGQKGDAGAPGPQGPSGAPGP--------QGPTGVTGPKGARGAQGPPGATGFP 830 Query: 1273 -KSGRSSSLDGEHHDGYHRDEPFGGPPGS----GTPSRGGRSGSNWGRGSNMNSGPPRRG 1327 +GR GPPGS G P G SG + +G+ +SGPP R Sbjct: 831 GAAGRV------------------GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRA 872 Query: 1328 ASRG 1331 G Sbjct: 873 GEPG 876 Score = 236 bits (601), Expect = 1e-61 Identities = 271/905 (29%), Positives = 335/905 (37%), Gaps = 169/905 (18%) Query: 575 PPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 P +G+P +GP+ PG+ +G P + N Q GP GP G P GP G Sbjct: 245 PGENGSPGPMGPRGLPGE-------RGRTGPAGAAGARGNDGQPGPAGPPG---PVGPAG 294 Query: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPP 693 G G P +G GP G GP+G QGP +G P GP G +PG G G +G Sbjct: 295 GPGFPGAPGAKGEAGPTGARGPEGAQGP-RGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 353 Query: 694 GPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGP---------QGHLGPQGPPGTQGMQGPP 744 G G +G G GP+GPPGPQG GP GP G +G GP+G PG G QG P Sbjct: 354 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 413 Query: 745 GPRGMQ------------GPPHPHGIQGGPGSQGIQG----------PVSQGPLMGLNPR 782 GP G + GP P G +G PG++G G P +GP P+ Sbjct: 414 GPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPK 473 Query: 783 GMQGPPG-PRENQGPAPQGMIMGHP----PQEMRGPHPPGGLLGH----GPQEMRGPQEI 833 G G PG P E P +G + G P PQ GP G G GPQ RG + Sbjct: 474 GANGDPGRPGEPGLPGARG-LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 532 Query: 834 RGMQGP------PPQGSMLGPP--QELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGP 883 G GP P + G P LRG PG + G P G GP + G QG PGP Sbjct: 533 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 592 Query: 884 QGQQN-------PARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGP-----PPLI 931 G Q P G P +P + L+G F E S G P + Sbjct: 593 SGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGL 652 Query: 932 PGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHH-----MGPMSERRHEQSGGPEHGP 985 PG G G +G P P GP +G P GP +R GPE P Sbjct: 653 PGTPGTDGPKGASGPAGPPGAQGP--PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAP 710 Query: 986 ER-------GPF--------------------RGGQDCRGPPDRRG-PHPDFPDDFSRPD 1017 + GP G RG P RG P P F+ P Sbjct: 711 GKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770 Query: 1018 DFHPDKRFGHRLREFEG-----RGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARG 1072 D + G + + E G P PQ G PGP P + G A+G Sbjct: 771 G--ADGQPGAKGEQGEAGQKGDAGAPGPQGPS---GAPGPQGPTG---VTGPKGARGAQG 822 Query: 1073 PPGAW-----EGR--RPGDERFPRDPEDPRFRGRREESFRRG--------APPRHEGRAP 1117 PPGA GR PG P P P G+ RG P +G A Sbjct: 823 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAG 882 Query: 1118 PRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGR 1177 P G G PG + E + A R + G G G LP P P +G Sbjct: 883 PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG-LPGPSGEPGKQGA- 940 Query: 1178 KPDSWDGNREPGP----------GHEHFRDTPRPDHPP-HDGHSPASRER-SSSLQGMDM 1225 P + PGP G +P D PP DG + +R + G Sbjct: 941 -PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPG 999 Query: 1226 ASLPPRKRPWHDGP----GTSEHREMEAPGGPSEDRGGKGRGGP-GPAQRVPKSGRSSSL 1280 A PP P GP G + P GPS G +G GP GP ++G Sbjct: 1000 APGPPGS-PGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1058 Query: 1281 DGEHHDGYHRDEPFGGPPG-SGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG-------- 1331 + H G+ + GPPG SG G +G + RG GP + + G Sbjct: 1059 GLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1118 Query: 1332 GGRGR 1336 G RGR Sbjct: 1119 GPRGR 1123 Score = 226 bits (575), Expect = 1e-58 Identities = 202/610 (33%), Positives = 245/610 (40%), Gaps = 94/610 (15%) Query: 565 AQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQG 624 A ++ EQ P PS L GP PG+G QG + + + G PG +G Sbjct: 581 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG-DQGVPGEAGAPGLVGPRGERGFPGERG 639 Query: 625 QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP---QGPP--QGLPRPQDMHGPQGMQR 679 PG QG GP+G P G GP+G GP GP QGPP QG+P + G G + Sbjct: 640 S---PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKG 696 Query: 680 HPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG 739 G G GP+G PG G G G +GP GP G G G GPPGP G G +G PG +G Sbjct: 697 DRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 756 Query: 740 MQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG-PAP 798 GPPGP G GPP G G PG++G QG Q +G G PGP+ G P P Sbjct: 757 ETGPPGPAGFAGPP---GADGQPGAKGEQGEAGQ--------KGDAGAPGPQGPSGAPGP 805 Query: 799 QGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGS 858 QG P + GP G GP G G GPP GPP GPPG Sbjct: 806 QG------PTGVTGPKGARG--AQGPPGATGFPGAAGRVGPPGSNGNPGPP----GPPGP 853 Query: 859 QSQQGP--PQGSLGPPPQG---GMQGPPGPQGQQNPA--RGPHPSQGPIPFQQQKTPLLG 911 + GP +G GPP + G+QGP GP G++ GP ++GP Sbjct: 854 SGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP------------ 901 Query: 912 DGPRAPFNQEGQSTGPPPLIPGL-GQQGAQG----RIPPLNPGQGPGPNKGDSRGPPN-- 964 GP+ Q G I GL GQ+G +G P PG+ P RGPP Sbjct: 902 PGPQGLAGQRG--------IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953 Query: 965 ---HHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHP 1021 GP E E S G + P R G + RG G P P P P Sbjct: 954 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA-PGAPGPPGSPGPAGP 1012 Query: 1022 DKRFGHRLREFEGRGGPL----------------PQEEKWRRGGPGPPFPPDHREFSEGD 1065 + G R G GP+ P+ +K G PG HR F+ Sbjct: 1013 TGKQGDRGE--AGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1070 Query: 1066 GRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFP 1125 G GP G P PR P P ++ + P G PRGR G Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA---NGIPGPIGPPGPRGRSGET 1127 Query: 1126 GPEDFGPEEN 1135 GP GP N Sbjct: 1128 GPA--GPPGN 1135 Score = 192 bits (488), Expect = 2e-48 Identities = 145/394 (36%), Positives = 171/394 (43%), Gaps = 61/394 (15%) Query: 574 PPPSSGTPLLGPQ-PFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632 P SG P GPQ P GP +G Q P + P ++GPPG G PPGP Sbjct: 796 PQGPSGAP--GPQGPTGVTGPKGA--RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPP 851 Query: 633 GQMGPQGPPLHQGGGGPQGFMGP---QGPQGPP--------------QGLPRPQDMHGPQ 675 G G GP +G GP G G QGP GPP +G P PQ + G + Sbjct: 852 GPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQR 911 Query: 676 GMQRHPGPHGPLG------PQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHL 729 G+ PG G G P G PG QG+ G G GP GP GP G GP G PG +G Sbjct: 912 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSP 971 Query: 730 GPQGPPGTQGMQG---------------PPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQG 774 G GPPG G G PGP G GP P G QG G G QGP+ G Sbjct: 972 GADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPM--G 1029 Query: 775 PLMGLNPRGMQGPPGPRENQG----PAPQGMIMGHPP----QEMRGPHPPGGLLG-HGPQ 825 P RG+QGP GPR ++G P +G+ GH Q + GP P G G GP Sbjct: 1030 PSGPAGARGIQGPQGPRGDKGEAGEPGERGL-KGHRGFTGLQGLPGPPGPSGDQGASGPA 1088 Query: 826 EMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG 885 GP+ G GP + G P + GPPG + + G G GPP G GPPGP G Sbjct: 1089 GPSGPRGPPGPVGPSGKDGANGIPGPI-GPPGPRGRSGET-GPAGPPGNPGPPGPPGPPG 1146 Query: 886 ---QQNPARGPHP-SQGPIPFQQQKTPLLGDGPR 915 + G P +GP P Q + G R Sbjct: 1147 PGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLR 1180 Score = 140 bits (354), Expect = 6e-33 Identities = 99/252 (39%), Positives = 109/252 (43%), Gaps = 21/252 (8%) Query: 574 PPPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632 PP G P L GP PG+ + G P G G G PGP Sbjct: 949 PPGPVGPPGLTGPAGEPGR----EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPP 1004 Query: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQ 690 G GP GP QG G G GP GP GP +G+ PQ G +G PG G G + Sbjct: 1005 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHR 1064 Query: 691 GPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQ 750 G G QG GP G G QG GP G GP+GPPGP G G G G G GPPGPRG Sbjct: 1065 GFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRS 1124 Query: 751 GPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEM 810 G P G G PG G GP P G++ G GPRE +GP P Q M Sbjct: 1125 GETGPAGPPGNPGPPGPPGP----PGPGIDMSAFAG-LGPRE-KGP--------DPLQYM 1170 Query: 811 RGPHPPGGLLGH 822 R GGL H Sbjct: 1171 RADQAAGGLRQH 1182 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 248 bits (633), Expect = 3e-65 Identities = 271/827 (32%), Positives = 320/827 (38%), Gaps = 132/827 (15%) Query: 583 LGPQPFPGQG-----PMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGP 637 LGPQ PGQ P P G S P N G GP G P GPQGQ G Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406 Query: 638 QGPPLH---------------QGGGGPQGFMGPQGPQGP--PQGLPRPQDMHGPQGMQRH 680 GPP G GP G G GP G P G P PQ GPQG++ Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466 Query: 681 PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPP---GPQGHLGPQGPPGT 737 PG G G +G GP+G GP G GP GPPG +G GP+G P GP G +G +G PG Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526 Query: 738 QGMQGP---PGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQ 794 +G G PGP+G QG P G G GSQG G + L G RG+ G PG Q Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG--ARGLTGNPGV---Q 581 Query: 795 GPAPQGMIMGHPPQEMRGPHPPG--GLLGH-GPQEMRGPQEIRGMQGPPPQGSMLGPPQE 851 GP + +G P ++ R P PPG G+ G G + GP+ G G P + G P + Sbjct: 582 GPEGKLGPLGAPGEDGR-PGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640 Query: 852 LRGPPGSQSQQGPPQGSLGPP---PQGGMQGPPGPQGQQN-PARGPHPSQGPIPFQQQKT 907 RG PG + G P G +GPP + G QGPPGP G Q P P +G P Q Sbjct: 641 -RGAPGKDGEVG-PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ--- 695 Query: 908 PLLGD----GPRAPFNQEGQ--STGPPPLIPGLGQQGAQGRIPPLNPGQGPGPN--KGDS 959 + GD GP P + G G P + G++G G P P PGP+ GD+ Sbjct: 696 GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT 755 Query: 960 RGPPNHH-----------MGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPD 1008 GPP GP +R G E RG GPP GP + Sbjct: 756 -GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGE 814 Query: 1009 FPDDFSRPDDFHPDKRFGHRLREFEGRGGPL----PQEEKWRRGGPGPPFPPDHREFSEG 1064 + R P R R G G + PQ + G G P P + + Sbjct: 815 KGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGS 874 Query: 1065 DGRGAARGPPGAWEGRRPGDERFPRDPED-PRFRGRREESFRRGAP--PRHEGRAPPRGR 1121 G G PG P P P +G R GA P GR P G Sbjct: 875 PGPQGLAGSPG------------PHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGP 922 Query: 1122 DGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDS 1181 G PGP GP + +E G LRG R G +G P G D Sbjct: 923 AGAPGPA--GPLG--EPGKEGPPG--LRGDPGSHGRVGDRG--------PAGPPGGPGDK 968 Query: 1182 WDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGM-------DMASLP-PRKR 1233 D + PG PD PP PA + GM M LP P Sbjct: 969 GDPGEDGQPG---------PDGPP----GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGT 1015 Query: 1234 PWHDGP-GTSEHREMEAPGGPSEDRGGKGRGGP-GPAQRVPKSGRSSSLDGEHHDGYHRD 1291 P GP G + + P GP G G GP GPA GR ++ GE D D Sbjct: 1016 PGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAV-GERGD--RGD 1072 Query: 1292 EPFGGPPGS----GTPSRGGRSGSNWGR---GSNMNSGPPRRGASRG 1331 G PGS GTP G G R GS GPP R RG Sbjct: 1073 PGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRG 1119 Score = 236 bits (602), Expect = 1e-61 Identities = 268/885 (30%), Positives = 327/885 (36%), Gaps = 212/885 (23%) Query: 579 GTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQ---------------MPMNMAQMGPPGPQ 623 G P P P P P G +P +Q MP ++ +GP GPQ Sbjct: 165 GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQ 224 Query: 624 GQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--------------------- 662 G G QG GP GPP G GP G +G +GP+GPP Sbjct: 225 GL---QGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFA 281 Query: 663 -----------------------QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSS 699 +GL P+ G G + GP GP+G GP GP+G Sbjct: 282 GSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMP 341 Query: 700 GPQGHMGPQGPPGPQGHIGPQGPPGPQGHL---------------GPQGPPGTQGMQGPP 744 G +G +GPQG PG +G G G PGP G L G GP G +G +GP Sbjct: 342 GERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQ 401 Query: 745 GPRGMQGPPHPHGIQGGPGSQGIQG-PVSQGPLMGLNPRGMQGPPGPRENQG-PAPQGMI 802 G RG GPP P G G PG+ G G P ++GP G GPPG G P PQG Sbjct: 402 GQRGETGPPGPVGSPGLPGAIGTDGTPGAKGP---TGSPGTSGPPGSAGPPGSPGPQG-- 456 Query: 803 MGHPPQEMRG-PHPPG--GLLGH-GPQEMRGPQEIRGMQGPPPQGSMLGPPQE--LRGPP 856 PQ +RG P PG G G GP+ GP I+G GPP + GP + GPP Sbjct: 457 -STGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPP 515 Query: 857 GSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNP--ARGPHPSQGPIPFQQQKTPLLG--- 911 G ++G P G+ G P G+ GP G QG++ P + GP SQG P + + L G Sbjct: 516 GPVGERGAP-GNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGD-PGRPGEPGLPGARG 573 Query: 912 ----------DGPRAPFNQEGQS--TGPPPLIPGLGQQGAQGRIPPLNPGQGPG-PNKGD 958 +G P G+ GPP I GQ G+ G P PG P + Sbjct: 574 LTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG 633 Query: 959 SRGPPNHHMGPMSERRHEQSG--GP-----EHGPERGP-----FRGGQDCRGPPDRRGPH 1006 + G P P + SG GP E G E+GP F+G GPP G Sbjct: 634 NAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERG-EQGPPGPTGFQGLPGPPGPPGEGGK- 691 Query: 1007 PDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPL-PQEEKWRRGGPGPPFPPDHREFSEGD 1065 P D P D G GPL P+ E RG PG P Sbjct: 692 ---PGDQGVPGD--------------PGAVGPLGPRGE---RGNPGERGEPGITGLPGEK 731 Query: 1066 GRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAP-PR----------HEG 1114 G GP G PG P D P +G E G P P+ EG Sbjct: 732 GMAGGHGPDG--PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEG 789 Query: 1115 RAPPRGRDGFPGPEDFGPE----ENFDASEEAARGRDLRGRGRGTPRG-GRKGLLPTPDE 1169 A G G PGP GP + E RG RG P G G P Sbjct: 790 TAGNDGARGLPGP--LGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENG----PTG 843 Query: 1170 FPRFEGGRKPDSWDGNR-EPG-PGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMAS 1227 F G + PD G + EPG PG + +P P QG +A Sbjct: 844 AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP-------------------QG--LAG 882 Query: 1228 LPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGR-GGPGPAQRVPKSGRSSSLDGEHHD 1286 P P + PG R + P G + G GR G PGPA +G Sbjct: 883 SPGPHGP-NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG----------- 930 Query: 1287 GYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 P G P G P G GS+ G +GPP +G Sbjct: 931 ------PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKG 969 Score = 228 bits (581), Expect = 3e-59 Identities = 253/818 (30%), Positives = 319/818 (38%), Gaps = 123/818 (15%) Query: 575 PPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 P +SG P GP PG PQG P + P + G G G PGP G Sbjct: 437 PGTSGPPGSAGPPGSPG-------PQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHG 489 Query: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGP--------PQGLPRPQDMHGPQGMQRHPGPHG 685 GP GPP +G GP+G G GP GP +G P + GP+G Q GP G Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVG 549 Query: 686 PLGPQGP------------PGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQG 733 GP+G PG +G +G G GP+G GP G G G PGP G +G +G Sbjct: 550 SSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG 609 Query: 734 PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ-GPLMGLNP------RGMQG 786 PG+ G+ GP G G G P G G PG +G G + GP + P RG QG Sbjct: 610 QPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG 669 Query: 787 PPGPRENQG----PAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIR---GMQGP 839 PPGP QG P P G G P + P PG + GP+ RG R G+ G Sbjct: 670 PPGPTGFQGLPGPPGPPG--EGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGL 727 Query: 840 PPQGSMLG-----PPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQN--PARG 892 P + M G P+ GP G+ GPP G G P + G+ G PGP+G + +G Sbjct: 728 PGEKGMAGGHGPDGPKGSPGPSGTPGDTGPP-GLQGMPGERGIAGTPGPKGDRGGIGEKG 786 Query: 893 PHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLI--PG-LGQQGAQGRIPPLNPG 949 + G + PL GP P ++G+ GP L+ PG G G++G P Sbjct: 787 AEGTAGNDGARGLPGPLGPPGPAGPTGEKGE-PGPRGLVGPPGSRGNPGSRGENGPTGAV 845 Query: 950 QGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPE--------HGPERGP-FRGGQDCRGPP 1000 GP D + G ++ S GP+ HGP P +GG+ +GPP Sbjct: 846 GFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPP 905 Query: 1001 DRRGPHPDFPDDFSRPDDFHPDKRFGHR--LRE--FEG----RGGPLPQEEKWRRGGPGP 1052 G FP R P G L E EG RG P RG GP Sbjct: 906 GATG----FPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGP 961 Query: 1053 PFPPDHREFSEGDGRGAARGPPG-----------AWEGRRPGDERFPRDPEDPRFRGRRE 1101 P P + DG+ GPPG G+R G+ P P G+ Sbjct: 962 PGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQR-GERGMPGLPGPAGTPGKVG 1020 Query: 1102 ESFRRG--APPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRD----LRG-RGRG 1154 + G PP G G G PGPE GP A + GRD RG RG Sbjct: 1021 PTGATGDKGPPGPVGPPGSNGPVGEPGPE--GP-----AGNDGTPGRDGAVGERGDRGDP 1073 Query: 1155 TPRG--GRKGLLPTPDEF-PRFEGGRKPDSWDGNREP--GPGHEHFRDTPRP-------- 1201 P G G +G TP + G++ D G+R P PG R P P Sbjct: 1074 GPAGLPGSQGAPGTPGPVGAPGDAGQRGD--PGSRGPIGPPGRAGKRGLPGPQGPRGDKG 1131 Query: 1202 DHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKG 1261 DH + LQG+ P ++ PG R P GPS GK Sbjct: 1132 DHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPS----GK- 1186 Query: 1262 RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG 1299 G PGP + G S+ +G + GPPG Sbjct: 1187 EGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPG 1224 Score = 203 bits (517), Expect = 8e-52 Identities = 204/607 (33%), Positives = 244/607 (40%), Gaps = 131/607 (21%) Query: 564 LAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQ 623 LA ++ EQ P P+ L GP PG+G Q +P + +GP GP+ Sbjct: 661 LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKP----------GDQGVPGDPGAVGPLGPR 710 Query: 624 GQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGP 683 G+ PG +G+ G G P G G G GP GP+G P P D GP G+Q PG Sbjct: 711 GERGNPGERGEPGITGLP---GEKGMAGGHGPDGPKGSPGPSGTPGDT-GPPGLQGMPGE 766 Query: 684 HGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGP 743 G G GP G +G G +G G G G +G GP GPPGP G G +G PG +G+ GP Sbjct: 767 RGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGP 826 Query: 744 PGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG-PAPQGMI 802 PG RG G +G G G G QGP Q + +G G PG + + G P PQG + Sbjct: 827 PGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV-----KGEPGEPGQKGDAGSPGPQG-L 880 Query: 803 MGHPPQEMRGPHPPGGLLG-------HGPQEMRGPQEIRGMQGPPPQGSMLGP------- 848 G P GPH P G+ G GP G G GPP GP Sbjct: 881 AGSP-----GPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935 Query: 849 ----PQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQ 904 P LRG PGS + G +G GPP G +G PG GQ P Sbjct: 936 GKEGPPGLRGDPGSHGRVG-DRGPAGPPGGPGDKGDPGEDGQPGP--------------- 979 Query: 905 QKTPLLGDGPRAPFNQEGQS--TGPPPLIPGLGQQGAQGRIPPLNPGQ-GPGPNKGDSRG 961 DGP P GQ G P G G G P PG+ GP GD +G Sbjct: 980 -------DGPPGPAGTTGQRGIVGMPGQRGERGMPGLPG--PAGTPGKVGPTGATGD-KG 1029 Query: 962 PPNHHMGPMSERRHEQSGGP--EHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDF 1019 PP GP+ S GP E GPE GP G D G P R G Sbjct: 1030 PP----GPVGP---PGSNGPVGEPGPE-GP--AGND--GTPGRDG--------------- 1062 Query: 1020 HPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPP----FPPDHREFSEGDGRGAARGPPG 1075 + E RG P P +G PG P P D + + RG GPPG Sbjct: 1063 --------AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPI-GPPG 1113 Query: 1076 AWEGRR--PGDERFPRDPEDPRFRGRREESFRRG--------APPRHEGRAPPRGRDGFP 1125 G+R PG + D D RG R + RG PP G +G G P Sbjct: 1114 R-AGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGE---QGSAGIP 1169 Query: 1126 GPEDFGP 1132 GP FGP Sbjct: 1170 GP--FGP 1174 Score = 199 bits (506), Expect = 1e-50 Identities = 184/573 (32%), Positives = 225/573 (39%), Gaps = 97/573 (16%) Query: 574 PPPSSGTPLLGPQPFPGQ----GPMSQIPQGFQQPHPSQQ-------MPMNMAQMGPPGP 622 PP G P G Q PG GP+ P+G ++ +P ++ +P G GP Sbjct: 685 PPGEGGKP--GDQGVPGDPGAVGPLG--PRG-ERGNPGERGEPGITGLPGEKGMAGGHGP 739 Query: 623 QGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRP--QDMHGPQGMQRH 680 G PGP G G GPP QG G +G G GP+G G+ + G G + Sbjct: 740 DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799 Query: 681 PGPHGPLGPQGPPGPQGSSGPQGHMGP------------QGPPGPQGHIGPQGPPGPQGH 728 PGP GP GP GP G +G GP+G +GP GP G G GPQGP G G Sbjct: 800 PGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV 859 Query: 729 LGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPG---SQGIQGPVSQGPLMGLNPRGMQ 785 G G PG +G G PGP+G+ G P PHG G PG +G QGP G G Sbjct: 860 KGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPG--SAGRV 917 Query: 786 GPPGPRENQGPA-PQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMRGPQEIRGMQGPPPQG 843 GPPGP GPA P G P +RG G +G GP G +G G Q Sbjct: 918 GPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQP 977 Query: 844 SMLGPP--------QELRGPPGSQSQQGPP--------QGSLGPPPQGGMQGPPGPQGQQ 887 GPP + + G PG + ++G P G +GP G +GPPGP G Sbjct: 978 GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037 Query: 888 NPARGPHPSQGPI-PFQQQKTP----LLGD-------GPRA-PFNQEGQSTGPPPLIPG- 933 + GP GP P TP +G+ GP P +Q T P PG Sbjct: 1038 G-SNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGD 1096 Query: 934 LGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGG 993 GQ+G G P+ P P + RG P GP ++ G F G Sbjct: 1097 AGQRGDPGSRGPIGP-----PGRAGKRGLPGPQ-GPRGDKGDHGDRGDRGQKGHRGFTGL 1150 Query: 994 QDCRGPPDRRGPHPD--FPDDFSRPDDFHPDKRFGHRLREFEGRGGPL------------ 1039 Q GPP G P F P G EG GPL Sbjct: 1151 QGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGK-----EGNPGPLGPIGPPGVRGSV 1205 Query: 1040 ----PQEEKWRRGGPGPPFPPDHREFSEGDGRG 1068 P+ G PGPP PP H + GD G Sbjct: 1206 GEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMG 1238 Score = 196 bits (499), Expect = 1e-49 Identities = 160/474 (33%), Positives = 195/474 (41%), Gaps = 64/474 (13%) Query: 572 IQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP 631 + PP S G P + GP + GF P P + G PG +G PGP Sbjct: 824 VGPPGSRGNPGSRGE----NGPTGAV--GFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP 877 Query: 632 QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGP 689 QG G GP G G G G +G QGPP G P GP G PGP GPLG Sbjct: 878 QGLAGSPGP---HGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGE 934 Query: 690 ---QGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGP 746 +GPPG +G G G +G +GP GP G G +G PG G GP GPPG G G G Sbjct: 935 PGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGI 994 Query: 747 RGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHP 806 GM G G+ G PG G G V GP +G GP GP + GP + G P Sbjct: 995 VGMPGQRGERGMPGLPGPAGTPGKV--GPTGATGDKGPPGPVGPPGSNGPVGEPGPEG-P 1051 Query: 807 PQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP- 865 P G + G + GP + G QG P G P + G PG Q+G P Sbjct: 1052 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAP------GTPGPV-GAPGDAGQRGDPG 1104 Query: 866 -QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQS 924 +G +GPP + G +G PGPQG + +G H +G + QK G R +G Sbjct: 1105 SRGPIGPPGRAGKRGLPGPQGPRGD-KGDHGDRGD---RGQK------GHRGFTGLQGLP 1154 Query: 925 TGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHG 984 GPP G G G P P GP+ + P +GP R GPE Sbjct: 1155 -GPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGP 1213 Query: 985 P-ERGPFRGGQDCRGPPDRRG-------------------PHPDFPDDFSRPDD 1018 P E GP GPP G P P+F +D + PDD Sbjct: 1214 PGEPGP-------PGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDD 1260 Score = 181 bits (460), Expect = 3e-45 Identities = 247/798 (30%), Positives = 295/798 (36%), Gaps = 197/798 (24%) Query: 628 PPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPL 687 PPG + Q P GGG G +G +G P GL P G Sbjct: 88 PPGECCPVCSQTP----GGGNTNFGRGRKGQKGEP-GLV--------------PVVTGIR 128 Query: 688 GPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGP---- 743 G GP GP GS GP+G GP+G PGP+G G G PG G G GPPG GP Sbjct: 129 GRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLS 188 Query: 744 -----------------------PGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ----GPL 776 PG G GP P G+QG G G GP + GP+ Sbjct: 189 RPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPM 248 Query: 777 MGLNPRGMQGPPG-PRENQGPAPQG----MIMGHPPQEMRGPHPPG--GLLGH------- 822 + RG +GPPG P E+ P G + P P PG GL GH Sbjct: 249 GPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLE 308 Query: 823 GPQEMRGPQEIRGMQGPP-PQGSM--LGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQG 879 GP+ G +G GP P G+M LGP RG PG + + G PQG+ G GM G Sbjct: 309 GPKGEVGAPGSKGEAGPTGPMGAMGPLGP----RGMPGERGRLG-PQGAPGQRGAHGMPG 363 Query: 880 PPGPQGQQN-PARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPP-----PLIPG 933 PGP G P P G + + P GP P Q G+ TGPP P +PG Sbjct: 364 KPGPMGPLGIPGSSGFP--GNPGMKGEAGPTGARGPEGPQGQRGE-TGPPGPVGSPGLPG 420 Query: 934 -LGQQGAQG-RIPPLNPG-QGPGPNKGDSRGP-PNHHMGPMSERRHEQSGGP-------E 982 +G G G + P +PG GP + G P P GP R Q G P E Sbjct: 421 AIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR--GQPGDPGVPGFKGE 478 Query: 983 HGP--ERGPFRGGQDCRGPP---DRRGPHPDFPDDFSRPDDFHPDKRFGHR----LREFE 1033 GP E GP G Q GPP +RGP D P P G R R F Sbjct: 479 AGPKGEPGP-HGIQGPIGPPGEEGKRGPRGD-------PGTVGPPGPVGERGAPGNRGFP 530 Query: 1034 GRGG-PLPQEEKWRRGGPGPPFPPDHREFSEGD-GRGAARGPPGAW-----------EGR 1080 G G P P+ + RG G P + S+GD GR G PGA EG+ Sbjct: 531 GSDGLPGPKGAQGERGPVGSSGP----KGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586 Query: 1081 -----RPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEEN 1135 PG++ P P RG+ P G P+G G PG P E Sbjct: 587 LGPLGAPGEDGRPGPPGSIGIRGQ----------PGSMGLPGPKGSSGDPGK----PGEA 632 Query: 1136 FDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHF 1195 +A RG + G P G P P G R G + P PG F Sbjct: 633 GNAGVPGQRGAPGKD-GEVGPSG--------PVGPPGLAGER------GEQGP-PGPTGF 676 Query: 1196 RDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSE 1255 + P P PP +G P QG+ PG P GP Sbjct: 677 QGLPGPPGPPGEGGKPGD-------QGVP------------GDPGA------VGPLGPRG 711 Query: 1256 DRGGKG-RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWG 1314 +RG G RG PG + G + G+ D P G P SGTP G G Sbjct: 712 ERGNPGERGEPGITGLPGEKGMAG--------GHGPDGPKGSPGPSGTPGDTGPPGLQGM 763 Query: 1315 RGSNMNSGPPRRGASRGG 1332 G +G P RGG Sbjct: 764 PGERGIAGTPGPKGDRGG 781 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 247 bits (630), Expect = 6e-65 Identities = 246/770 (31%), Positives = 302/770 (39%), Gaps = 167/770 (21%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 GPPGP G G G++GP+G P G GP+G +GP+G G P G P + GP Sbjct: 634 GPPGPPGDDGMRGEDGEIGPRGLP---GEAGPRGLLGPRGTPGAP-GQPGMAGVDGP--- 686 Query: 678 QRHPGPHGPLGPQGPPGP---QGSSGPQGHMGPQGPPGPQGHIGPQGPP---------GP 725 PGP G +GPQG PGP QG+ GPQG GPQGP GP G GPQG P GP Sbjct: 687 ---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 743 Query: 726 QGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ------------ 773 GH G +G G +G GPPGP+G G P P G++G G +G++G + Sbjct: 744 PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 803 Query: 774 -------GPLMGLNPRGMQGPPGPRENQG----PAPQGM-----------IMGHPPQEMR 811 G + + PRG GP GP+ G P P G + G+P ++ Sbjct: 804 MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ-- 861 Query: 812 GPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGP 871 GP G G G + RG+ G P GP GP GS+ +G P G GP Sbjct: 862 GPKGSTGFPGF--PGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARG-PTGKPGP 914 Query: 872 PPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLI 931 G GPPGP G+ RGP QGP+ F K GP P ++G P Sbjct: 915 KGTSGGDGPPGPPGE----RGPQGPQGPVGFPGPK------GPPGPPGKDGL-----PGH 959 Query: 932 PG-LGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPF 990 PG G+ G QG+ P PG GP P GP+ ER H GP Sbjct: 960 PGQRGETGFQGKTGPPGPGGVVGPQ------GPTGETGPIGERGHPGPPGPP-------- 1005 Query: 991 RGGQDCRGPPDRRGPHPD-FPDDFSRPDDFHPDKRFGHRLREFEG-RGGPLPQEEKWRRG 1048 G Q G + G D P S D LR F G RG P Q +G Sbjct: 1006 -GEQGLPGAAGKEGAKGDPGPQGISGKDG-------PAGLRGFPGERGLPGAQGAPGLKG 1057 Query: 1049 GPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGA 1108 G GP PP G GP G RPG P+ P P + +GA Sbjct: 1058 GEGPQGPPGPVGSPGERGSAGTAGPIGL--PGRPG----PQGPPGP--------AGEKGA 1103 Query: 1109 PPRHEGRAPPRGRDGFPGPEDF-GPEENFDASEEAARGRDLRGRGRGTPRG--GRKGLLP 1165 P +G P GRDG GP GP + E ++ G+ +G G G Sbjct: 1104 -PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG--- 1159 Query: 1166 TPDEFPRFEGG-RKPDSWDGNREPGP----------GHEHFRDTPRPDHPPHDGHSPASR 1214 P P +G P G+ EPGP G E R P P P Sbjct: 1160 -PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP---------- 1208 Query: 1215 ERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKS 1274 LQG+ PP ++ + G P GP RG +G G Q P S Sbjct: 1209 ---IGLQGLPG---PPGEKGENGDVGPM------GPPGPPGPRGPQGPNGADGPQGPPGS 1256 Query: 1275 GRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 S GE + EP G G P G G RG +GPP Sbjct: 1257 VGSVGGVGE------KGEP-GEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1299 Score = 243 bits (619), Expect = 1e-63 Identities = 241/757 (31%), Positives = 300/757 (39%), Gaps = 140/757 (18%) Query: 592 GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQG 651 GP Q +G P S+ + GP G G PPGP G+ GPQGP GP G Sbjct: 889 GPRGQ--RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ------GPVG 940 Query: 652 FMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGP---LGPQGPPGPQGSSGPQGHMG 706 F GP+GP GPP GLP G G Q GP GP +GPQGP G G G +GH G Sbjct: 941 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPG 1000 Query: 707 PQGPPGPQGHIGPQGPPGPQGHLGPQG---PPGTQGMQGPPGPRGMQGPPHPHGIQGGPG 763 P GPPG QG G G G +G GPQG G G++G PG RG+ G G++GG G Sbjct: 1001 PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1060 Query: 764 SQGIQGPVS----QGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGL 819 QG GPV +G P G+ G PGP+ GPA + G P + +GP P G Sbjct: 1061 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE---KGAPGE--KGPQGPAGR 1115 Query: 820 LG-HGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP-----QGSLGPPP 873 G GP + GP G G +G P + +G G + + GPP QG +G P Sbjct: 1116 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ-KGSKGDKGENGPPGPPGLQGPVGAPG 1174 Query: 874 QGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQS--TGP--PP 929 G G PGP+GQQ G +G F P+ G P ++G++ GP PP Sbjct: 1175 IAGGDGEPGPRGQQGMF-GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1233 Query: 930 LIPG-LGQQGAQGRIPPLNP----------GQGPGPNKGDSRGPPNHHM--GPMSERRHE 976 PG G QG G P P G+ P + + GPP GP ER + Sbjct: 1234 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1293 Query: 977 QSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRG 1036 GP G +GPP GP + P P D P G Sbjct: 1294 GEAGPPGAA------GPPGAKGPPGDDGPKGN-PGPVGFPGDPGPP-----------GEP 1335 Query: 1037 GPLPQE----EKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAW--EGRRPGDERFPRD 1090 GP Q+ +K G PG P PP + G RGPPGA EGR+ G+ Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ-GE------ 1388 Query: 1091 PEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFG--PEENFDASEEAARGRDL 1148 +G + E+ G PP G P+G G PGPE P + A G+D Sbjct: 1389 ------KGAKGEAGAEG-PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD- 1440 Query: 1149 RGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDG 1208 G P G P P +G +PG E HP G Sbjct: 1441 ---GPPGPMG--------PPGLPGLKG-----------DPGSKGEK-------GHPGLIG 1471 Query: 1209 H-SPASRERSSSLQGMDMASLPPRKRPWHDG-PGTSEHREMEAPGGPSEDRGGKGRGGPG 1266 P + +G+ P G PG + P GP G G GP Sbjct: 1472 LIGPPGEQGEKGDRGL----------PGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP- 1520 Query: 1267 PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTP 1303 + PK + S+ G D GPPGS P Sbjct: 1521 ---QGPKGNKGSTGPA----GQKGDSGLPGPPGSPGP 1550 Score = 232 bits (592), Expect = 2e-60 Identities = 255/822 (31%), Positives = 315/822 (38%), Gaps = 157/822 (19%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 GP GP G PPG QG GP G P +G G G G G GPP + +G G Sbjct: 457 GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS 516 Query: 678 QRHP--------------------GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHI 717 + GP GP+G G PGP G G G G G PGPQG Sbjct: 517 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 576 Query: 718 GPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLM 777 G QGPPGP G G +G PG G +G PG G +G G+ G PG +G +G Sbjct: 577 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG-------- 628 Query: 778 GLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMRGPQEIRGM 836 RG QGPPGP + G + +G P+ + G P GLLG G G + G+ Sbjct: 629 ---ERGPQGPPGPPGDDGMRGEDGEIG--PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 683 Query: 837 QGPP-PQGSMLGPPQELRGPPGSQSQQGP-----PQGSLGPP----PQG--------GMQ 878 GPP P+G+M PQ GPPG Q GP PQG +GPP PQG G Sbjct: 684 DGPPGPKGNM--GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741 Query: 879 GPPGPQGQQNP-----ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ--STGPPPLI 931 GPPG G++ A GP QGPI + + DG R +G+ G P Sbjct: 742 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801 Query: 932 PGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFR 991 +G +G +G + + P GP R P GP Q+G E+G Sbjct: 802 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG-----QAG------EKGKL- 849 Query: 992 GGQDCRGPPDRRGP-----HPDFP----DDFSRPDDFHPDKRFGHR----LREFEGRGGP 1038 G G P R+GP P FP + +R P R G R R G GP Sbjct: 850 GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR-GQRGPTGPRGSRGARGP 908 Query: 1039 LPQE-EKWRRGGPGPPFPPDHR--EFSEGD-GRGAARGPPGAWEGRRPGDERFPRDP--- 1091 + K GG GPP PP R + +G G +GPPG PG + P P Sbjct: 909 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP-----PGKDGLPGHPGQR 963 Query: 1092 EDPRFRGRREESFRRG--APPRHEGRAPPRGRDGFPGPEDFGPEENFD--ASEEAARG-- 1145 + F+G+ G P G P G G PGP E+ A +E A+G Sbjct: 964 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1023 Query: 1146 --RDLRGRG-----RGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDT 1198 + + G+ RG P G +G LP P +GG P G PG T Sbjct: 1024 GPQGISGKDGPAGLRGFP--GERG-LPGAQGAPGLKGGEGPQGPPG-PVGSPGERGSAGT 1079 Query: 1199 ---------PRPDHPPHDG-----------HSPASRERSSSLQGMDMASLPPRKRPWHDG 1238 P P PP PA R+ G+ P P DG Sbjct: 1080 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP-GPAGPAGSPGEDG 1138 Query: 1239 PGTSEHREMEAPG--GPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHD-------GYH 1289 + E+ PG G D+G G GP Q + + DGE G Sbjct: 1139 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1194 Query: 1290 RDE---PFGGPPG----SGTPSRGGRSGSNWGRGSNMNSGPP 1324 DE F GPPG G P G G N G GPP Sbjct: 1195 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1236 Score = 228 bits (581), Expect = 3e-59 Identities = 263/860 (30%), Positives = 324/860 (37%), Gaps = 164/860 (19%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 PP G +GPQ PG P G Q Q +P +GPPG +G PG G Sbjct: 686 PPGPKGN--MGPQGEPG-------PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG 736 Query: 634 QMGPQGPPLH---------QGGGGPQGFMGPQGPQGP--------------------PQG 664 G GPP H +G GP G GP G GP G Sbjct: 737 LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 796 Query: 665 LPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPG 724 P + G +G + G GP G GP GP+G +GP G GP G G +G +G G PG Sbjct: 797 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 856 Query: 725 PQGHLGPQGP---PGTQGMQGPPGPRGMQGPPHPHGIQG--GP-GSQGIQGPVSQGPLMG 778 G GP+G PG G G G RG+ G P P G +G GP GS+G +GP + G Sbjct: 857 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916 Query: 779 LNPRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQ 837 + G GPPGP +GP PQG + P+ GP GL GH Q RG +G Sbjct: 917 TS--GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ--RGETGFQGKT 972 Query: 838 GPPPQGSMLGP--PQELRGPPGSQSQQGPP-----QGSLGPPPQGGMQGPPGPQ---GQQ 887 GPP G ++GP P GP G + GPP QG G + G +G PGPQ G+ Sbjct: 973 GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1032 Query: 888 NPA--RGPHPSQGPIPFQQQKTPLLG----DGPRAPFNQEGQ----STGPPPLIPG---- 933 PA RG P + +P Q L G GP P G+ T P +PG Sbjct: 1033 GPAGLRG-FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1091 Query: 934 ------LGQQGAQGRIPPLNPGQGPGPNKG-----DSRGPPNHHMGPMSERRHEQSGGPE 982 G++GA G P QGP G GP P + + G P Sbjct: 1092 QGPPGPAGEKGAPGEKGP----QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1147 Query: 983 HGPERGPFRGGQDCRGPPDRRGP--HPDFPDDFSRPDDFHPDKRFGHR----LREFEGRG 1036 +G +G GPP +GP P P FG + R F G Sbjct: 1148 QKGSKGD-KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1206 Query: 1037 GPL-------PQEEKWRRG--GP-GPPFPPDHREFSEGDGRGAARGPPGA-------WEG 1079 GP+ P EK G GP GPP PP R +G +GPPG+ E Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266 Query: 1080 RRPGDERFPRDPEDPRFRGRREESFRRG--APPRHEGRAPPRGRDGFPGPEDFGPEENFD 1137 PG+ P P + G + E +G PP G A P G G PG D GP+ N Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP---GAAGPPGAKGPPG--DDGPKGN-- 1319 Query: 1138 ASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNR--EPGPGHEHF 1195 D G P G+ G+ GG K + D + PGP E Sbjct: 1320 -PGPVGFPGDPGPPGEPGP-AGQDGV-----------GGDKGEDGDPGQPGPPGPSGEAG 1366 Query: 1196 RDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSE 1255 P P R+ +G A PP K GP P GP+ Sbjct: 1367 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGK----TGP--------VGPQGPAG 1414 Query: 1256 DRGGKG-RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFG--GPPG-SGTPSRGGRSGS 1311 G +G RG PGP G + +D P G GPPG G G G Sbjct: 1415 KPGPEGLRGIPGPVGEQGLPGAAG-----------QDGPPGPMGPPGLPGLKGDPGSKGE 1463 Query: 1312 NWGRGSNMNSGPPRRGASRG 1331 G GPP +G Sbjct: 1464 KGHPGLIGLIGPPGEQGEKG 1483 Score = 217 bits (552), Expect = 7e-56 Identities = 221/675 (32%), Positives = 261/675 (38%), Gaps = 161/675 (23%) Query: 573 QPPPSSGTPLLGPQPFPG----QGPMSQI----PQGFQQPHPSQQMPMNMAQMGPPGPQG 624 +P P + GP PG QGP + P+G P +P + Q G G QG Sbjct: 911 KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 970 Query: 625 QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP---QGPP--------QGLPRPQDMHG 673 + PPGP G +GPQGP G G +G GP GP QG P +G P PQ + G Sbjct: 971 KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1030 Query: 674 ---PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG 730 P G++ PG G G QG PG +G GPQG GP G PG +G G GP G G G Sbjct: 1031 KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1090 Query: 731 PQGPPGTQGMQGPPGPRGMQGP------------PHPHGIQGGPGSQGIQGPVSQ-GPLM 777 PQGPPG G +G PG +G QGP P P G G PG G +G + + G Sbjct: 1091 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1150 Query: 778 GLNPRGMQGPPGPRENQGP--AP--------------QGMIMGHPPQEMRG-PHPPG--- 817 +G GPPGP QGP AP QGM + RG P PPG Sbjct: 1151 SKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG 1210 Query: 818 --GLLGH----------GPQEMRGPQEIRGMQGPPPQGSMLGPPQEL--------RGPPG 857 GL G GP GP RG QGP GPP + +G PG Sbjct: 1211 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1270 Query: 858 SQSQQGPP--------------QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQ 903 GPP +G GPP G G GP G P P GP+ F Sbjct: 1271 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFP 1326 Query: 904 QQKTPLLGDGPRAPFNQEGQS-----------TGPPPLIPGLGQQGAQG-RIPPLNPG-- 949 P G P Q+G GPP G G G R PP G Sbjct: 1327 GDPGP---PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1383 Query: 950 --QGPGPNKGDS--RGPPNHHMGPMSERRHEQSGGPEH-----GP--ERG-PFRGGQDCR 997 QG KG++ GPP GP+ + GPE GP E+G P GQD Sbjct: 1384 GRQGEKGAKGEAGAEGPPGK-TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD-- 1440 Query: 998 GPPDRRGPHPDFP----DDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPP 1053 GPP GP P P D S+ + HP G P Q EK RG PG Sbjct: 1441 GPPGPMGP-PGLPGLKGDPGSKGEKGHPGL--------IGLIGPPGEQGEKGDRGLPG-- 1489 Query: 1054 FPPDHREFSEGDGRGAARGPPGA-WEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRH 1112 +G PGA +G PG P P G + +G+ Sbjct: 1490 ----------------TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS---- 1529 Query: 1113 EGRAPPRGRDGFPGP 1127 G A +G G PGP Sbjct: 1530 TGPAGQKGDSGLPGP 1544 Score = 202 bits (513), Expect = 2e-51 Identities = 154/422 (36%), Positives = 185/422 (43%), Gaps = 81/422 (19%) Query: 616 QMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGP------QGFMGPQGPQGPPQGLPRP- 668 Q G G +G+ PPGP G GP G P GG G QG G +G +G +G P P Sbjct: 1148 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA-RGFPGPP 1206 Query: 669 -----QDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPP 723 Q + GP G + G GP+GP GPPGP+G GP G GPQGPPG G +G G Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1266 Query: 724 GPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRG 783 G G G GPPG G+ GP G RG +G P G G PG++G P GP P G Sbjct: 1267 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG--PPGDDGPKGNPGPVG 1324 Query: 784 MQGPPGPRENQGPAPQGMIMGH--------------PPQEMRGPHPPG-----GLLG-HG 823 G PGP GPA Q + G P E P PPG G G G Sbjct: 1325 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1384 Query: 824 PQEMRGPQEIRGMQGPPPQGSMLGP--------PQELRGPPGSQSQQG--------PPQG 867 Q +G + G +GPP + +GP P+ LRG PG +QG P G Sbjct: 1385 RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1444 Query: 868 SLGPPPQGGMQGPPGPQGQQNPAR-----GPHPSQGP-----IPFQQQKTPLLGD----G 913 +GPP G++G PG +G++ GP QG +P Q GD G Sbjct: 1445 PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPG 1504 Query: 914 PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQ-GPGPNKGDS--RGPPNHHMGPM 970 P P G PP +P G QG +G N G GP KGDS GPP GP Sbjct: 1505 PAGPLGPPG-----PPGLP--GPQGPKG-----NKGSTGPAGQKGDSGLPGPPG-SPGPP 1551 Query: 971 SE 972 E Sbjct: 1552 GE 1553 Score = 189 bits (479), Expect = 2e-47 Identities = 136/367 (37%), Positives = 168/367 (45%), Gaps = 47/367 (12%) Query: 584 GPQPFPGQ-GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPL 642 G + FPG GP+ QG P + ++ MGPPGP G P GP G GPQGPP Sbjct: 1198 GARGFPGPPGPIGL--QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1255 Query: 643 HQG---GGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPG--- 694 G G G +G G G GPP G+ P+ G +G PG GP G +GPPG Sbjct: 1256 SVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDG 1315 Query: 695 PQGSSGP---QGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQG 751 P+G+ GP G GP G PGP G G G G G G GPPG G GPPGP G +G Sbjct: 1316 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1375 Query: 752 PPHPHGIQGGPGSQGIQG-------PVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMG 804 PP G +G G +G +G P GP+ P G GP G R GP + + G Sbjct: 1376 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1435 Query: 805 HPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQEL-----RGPPGSQ 859 Q+ PPG + G ++G +G +G P ++GPP E RG PG+Q Sbjct: 1436 AAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1491 Query: 860 SQQGP--------PQGSLGPP-------PQG--GMQGPPGPQGQQNPARGPHPSQGPIPF 902 G P G LGPP PQG G +G GP GQ+ + P P P P Sbjct: 1492 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1551 Query: 903 QQQKTPL 909 + PL Sbjct: 1552 GEVIQPL 1558 Score = 186 bits (472), Expect = 1e-46 Identities = 135/353 (38%), Positives = 155/353 (43%), Gaps = 47/353 (13%) Query: 583 LGPQPFPG----QGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQ 638 +GP PG QGP G Q P S + + G PG G PPG G GP+ Sbjct: 1230 MGPPGPPGPRGPQGPNGA--DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1287 Query: 639 GPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGS 698 G +G GP G GP G +GPP G P+ GP G PGP G GP G G G Sbjct: 1288 GERGEKGEAGPPGAAGPPGAKGPP-GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1346 Query: 699 SGPQGHMGPQGPPGPQGHIGPQGPP---------GPQGHLGPQGPPGTQGMQGPPGPRGM 749 G G G GPPGP G GP GPP G +G G +G G G +GPPG G Sbjct: 1347 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1406 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQE 809 GP P G G G +GI GPV + L G G GPPGP GP + G P + Sbjct: 1407 VGPQGPAGKPGPEGLRGIPGPVGEQGLPG--AAGQDGPPGP---MGPPGLPGLKGDPGSK 1461 Query: 810 MRGPHPPGGLLG----HGPQEMRGPQEIRGMQGPP----------PQGSMLGPPQELRGP 855 HP GL+G G Q +G + + G QG P P G LGPP GP Sbjct: 1462 GEKGHP--GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP-LGPP----GP 1514 Query: 856 PGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQK 906 PG QGP +GS GP Q G G PGP G P P P+P K Sbjct: 1515 PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP---PGEVIQPLPILSSK 1564 Score = 132 bits (332), Expect = 2e-30 Identities = 93/265 (35%), Positives = 108/265 (40%), Gaps = 54/265 (20%) Query: 575 PPSSGTPLLGPQP--FPGQ-GPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG 630 PP P P P FPG GP + P G + + Q GPPGP G+ PPG Sbjct: 1310 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1369 Query: 631 PQGQMGP------------QGPPLHQGGGGPQGFMGPQGPQGPP--------QGLPRPQD 670 P G+ GP +G G GP G GP GPQGP +G+P P Sbjct: 1370 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1429 Query: 671 MHGPQGMQRHPGPHGPLGPQG------------------------PPGPQGSSGPQGHMG 706 G G GP GP+GP G PPG QG G +G G Sbjct: 1430 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489 Query: 707 PQGPPGPQGH------IGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQG 760 QG PG +G GP GPPGP G GPQGP G +G GP G +G G P P G G Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549 Query: 761 GPGSQGIQGPVSQGPLMGLNPRGMQ 785 PG P+ + GMQ Sbjct: 1550 PPGEVIQPLPILSSKKTRRHTEGMQ 1574 Score = 90.9 bits (224), Expect = 7e-18 Identities = 155/571 (27%), Positives = 196/571 (34%), Gaps = 97/571 (16%) Query: 806 PPQEMRGPHPPG-------GLLGHGPQEMRGPQE----------IRGMQGPPPQGSMLGP 848 PP E GP P + GHG +G + + G GP ++GP Sbjct: 408 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 467 Query: 849 P--QELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP-IPFQQQ 905 P Q GPPG +GPP G G P G+ GPPG G S+GP I Q+ Sbjct: 468 PGLQGPTGPPGDPGDRGPP-GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA 526 Query: 906 KTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNH 965 + + R GPP G G GR P+ G G KG+S P Sbjct: 527 QAQAILQQARIALR------GPP------GPMGLTGRPGPVG-GPGSSGAKGESGDP--- 570 Query: 966 HMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRF 1025 GP R + GP P + G RG P G D Sbjct: 571 --GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD----------------- 611 Query: 1026 GHRLREFEGRGG-PLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRP-G 1083 R F+G G P + + RG GPP PP DG RG PG R G Sbjct: 612 ----RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 667 Query: 1084 DERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDF-GPEENFDA-SEE 1141 P P P G +G +G P G+ G PGP+ GP+ E+ Sbjct: 668 PRGTPGAPGQPGMAGVDGPPGPKGNMGP-QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 726 Query: 1142 AARGRD-LRGR-GRGTPRG--------GRKGLL--PTPDEFPRFEGGRKPDSWDGNRE-P 1188 +G+ L G G P G G KG L P P + G R DG R Sbjct: 727 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK 786 Query: 1189 GPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGP-GTSEHREM 1247 G E D P G +R ++ + PR DGP G Sbjct: 787 GSKGEKGED----GFPGFKGDMGLKGDRG------EVGQIGPRGE---DGPEGPKGRAGP 833 Query: 1248 EAPGGPSEDRGGKGR-GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRG 1306 GPS G KG+ G PG + G S G + ++ G +G P Sbjct: 834 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK--GARGVAGKPGPR 891 Query: 1307 GRSGSNWGRGSNMNSGPPRRGASRG--GGRG 1335 G+ G RGS GP + +G GG G Sbjct: 892 GQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 922 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 247 bits (630), Expect = 6e-65 Identities = 246/770 (31%), Positives = 302/770 (39%), Gaps = 167/770 (21%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 GPPGP G G G++GP+G P G GP+G +GP+G G P G P + GP Sbjct: 583 GPPGPPGDDGMRGEDGEIGPRGLP---GEAGPRGLLGPRGTPGAP-GQPGMAGVDGP--- 635 Query: 678 QRHPGPHGPLGPQGPPGP---QGSSGPQGHMGPQGPPGPQGHIGPQGPP---------GP 725 PGP G +GPQG PGP QG+ GPQG GPQGP GP G GPQG P GP Sbjct: 636 ---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 692 Query: 726 QGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ------------ 773 GH G +G G +G GPPGP+G G P P G++G G +G++G + Sbjct: 693 PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 752 Query: 774 -------GPLMGLNPRGMQGPPGPRENQG----PAPQGM-----------IMGHPPQEMR 811 G + + PRG GP GP+ G P P G + G+P ++ Sbjct: 753 MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ-- 810 Query: 812 GPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGP 871 GP G G G + RG+ G P GP GP GS+ +G P G GP Sbjct: 811 GPKGSTGFPGF--PGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARG-PTGKPGP 863 Query: 872 PPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLI 931 G GPPGP G+ RGP QGP+ F K GP P ++G P Sbjct: 864 KGTSGGDGPPGPPGE----RGPQGPQGPVGFPGPK------GPPGPPGKDGL-----PGH 908 Query: 932 PG-LGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPF 990 PG G+ G QG+ P PG GP P GP+ ER H GP Sbjct: 909 PGQRGETGFQGKTGPPGPGGVVGPQ------GPTGETGPIGERGHPGPPGPP-------- 954 Query: 991 RGGQDCRGPPDRRGPHPD-FPDDFSRPDDFHPDKRFGHRLREFEG-RGGPLPQEEKWRRG 1048 G Q G + G D P S D LR F G RG P Q +G Sbjct: 955 -GEQGLPGAAGKEGAKGDPGPQGISGKDG-------PAGLRGFPGERGLPGAQGAPGLKG 1006 Query: 1049 GPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGA 1108 G GP PP G GP G RPG P+ P P + +GA Sbjct: 1007 GEGPQGPPGPVGSPGERGSAGTAGPIGL--PGRPG----PQGPPGP--------AGEKGA 1052 Query: 1109 PPRHEGRAPPRGRDGFPGPEDF-GPEENFDASEEAARGRDLRGRGRGTPRG--GRKGLLP 1165 P +G P GRDG GP GP + E ++ G+ +G G G Sbjct: 1053 -PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG--- 1108 Query: 1166 TPDEFPRFEGG-RKPDSWDGNREPGP----------GHEHFRDTPRPDHPPHDGHSPASR 1214 P P +G P G+ EPGP G E R P P P Sbjct: 1109 -PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP---------- 1157 Query: 1215 ERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKS 1274 LQG+ PP ++ + G P GP RG +G G Q P S Sbjct: 1158 ---IGLQGLPG---PPGEKGENGDVGPM------GPPGPPGPRGPQGPNGADGPQGPPGS 1205 Query: 1275 GRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 S GE + EP G G P G G RG +GPP Sbjct: 1206 VGSVGGVGE------KGEP-GEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1248 Score = 243 bits (619), Expect = 1e-63 Identities = 241/757 (31%), Positives = 300/757 (39%), Gaps = 140/757 (18%) Query: 592 GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQG 651 GP Q +G P S+ + GP G G PPGP G+ GPQGP GP G Sbjct: 838 GPRGQ--RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ------GPVG 889 Query: 652 FMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGP---LGPQGPPGPQGSSGPQGHMG 706 F GP+GP GPP GLP G G Q GP GP +GPQGP G G G +GH G Sbjct: 890 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPG 949 Query: 707 PQGPPGPQGHIGPQGPPGPQGHLGPQG---PPGTQGMQGPPGPRGMQGPPHPHGIQGGPG 763 P GPPG QG G G G +G GPQG G G++G PG RG+ G G++GG G Sbjct: 950 PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1009 Query: 764 SQGIQGPVS----QGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGL 819 QG GPV +G P G+ G PGP+ GPA + G P + +GP P G Sbjct: 1010 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE---KGAPGE--KGPQGPAGR 1064 Query: 820 LG-HGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP-----QGSLGPPP 873 G GP + GP G G +G P + +G G + + GPP QG +G P Sbjct: 1065 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ-KGSKGDKGENGPPGPPGLQGPVGAPG 1123 Query: 874 QGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQS--TGP--PP 929 G G PGP+GQQ G +G F P+ G P ++G++ GP PP Sbjct: 1124 IAGGDGEPGPRGQQGMF-GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182 Query: 930 LIPG-LGQQGAQGRIPPLNP----------GQGPGPNKGDSRGPPNHHM--GPMSERRHE 976 PG G QG G P P G+ P + + GPP GP ER + Sbjct: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242 Query: 977 QSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRG 1036 GP G +GPP GP + P P D P G Sbjct: 1243 GEAGPPGAA------GPPGAKGPPGDDGPKGN-PGPVGFPGDPGPP-----------GEP 1284 Query: 1037 GPLPQE----EKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAW--EGRRPGDERFPRD 1090 GP Q+ +K G PG P PP + G RGPPGA EGR+ G+ Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ-GE------ 1337 Query: 1091 PEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFG--PEENFDASEEAARGRDL 1148 +G + E+ G PP G P+G G PGPE P + A G+D Sbjct: 1338 ------KGAKGEAGAEG-PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD- 1389 Query: 1149 RGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDG 1208 G P G P P +G +PG E HP G Sbjct: 1390 ---GPPGPMG--------PPGLPGLKG-----------DPGSKGEK-------GHPGLIG 1420 Query: 1209 H-SPASRERSSSLQGMDMASLPPRKRPWHDG-PGTSEHREMEAPGGPSEDRGGKGRGGPG 1266 P + +G+ P G PG + P GP G G GP Sbjct: 1421 LIGPPGEQGEKGDRGL----------PGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP- 1469 Query: 1267 PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTP 1303 + PK + S+ G D GPPGS P Sbjct: 1470 ---QGPKGNKGSTGPA----GQKGDSGLPGPPGSPGP 1499 Score = 232 bits (592), Expect = 2e-60 Identities = 255/822 (31%), Positives = 315/822 (38%), Gaps = 157/822 (19%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 GP GP G PPG QG GP G P +G G G G G GPP + +G G Sbjct: 406 GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS 465 Query: 678 QRHP--------------------GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHI 717 + GP GP+G G PGP G G G G G PGPQG Sbjct: 466 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 525 Query: 718 GPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLM 777 G QGPPGP G G +G PG G +G PG G +G G+ G PG +G +G Sbjct: 526 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG-------- 577 Query: 778 GLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMRGPQEIRGM 836 RG QGPPGP + G + +G P+ + G P GLLG G G + G+ Sbjct: 578 ---ERGPQGPPGPPGDDGMRGEDGEIG--PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 632 Query: 837 QGPP-PQGSMLGPPQELRGPPGSQSQQGP-----PQGSLGPP----PQG--------GMQ 878 GPP P+G+M PQ GPPG Q GP PQG +GPP PQG G Sbjct: 633 DGPPGPKGNM--GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690 Query: 879 GPPGPQGQQNP-----ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ--STGPPPLI 931 GPPG G++ A GP QGPI + + DG R +G+ G P Sbjct: 691 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750 Query: 932 PGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFR 991 +G +G +G + + P GP R P GP Q+G E+G Sbjct: 751 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG-----QAG------EKGKL- 798 Query: 992 GGQDCRGPPDRRGP-----HPDFP----DDFSRPDDFHPDKRFGHR----LREFEGRGGP 1038 G G P R+GP P FP + +R P R G R R G GP Sbjct: 799 GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR-GQRGPTGPRGSRGARGP 857 Query: 1039 LPQE-EKWRRGGPGPPFPPDHR--EFSEGD-GRGAARGPPGAWEGRRPGDERFPRDP--- 1091 + K GG GPP PP R + +G G +GPPG PG + P P Sbjct: 858 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP-----PGKDGLPGHPGQR 912 Query: 1092 EDPRFRGRREESFRRG--APPRHEGRAPPRGRDGFPGPEDFGPEENFD--ASEEAARG-- 1145 + F+G+ G P G P G G PGP E+ A +E A+G Sbjct: 913 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972 Query: 1146 --RDLRGRG-----RGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDT 1198 + + G+ RG P G +G LP P +GG P G PG T Sbjct: 973 GPQGISGKDGPAGLRGFP--GERG-LPGAQGAPGLKGGEGPQGPPG-PVGSPGERGSAGT 1028 Query: 1199 ---------PRPDHPPHDG-----------HSPASRERSSSLQGMDMASLPPRKRPWHDG 1238 P P PP PA R+ G+ P P DG Sbjct: 1029 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP-GPAGPAGSPGEDG 1087 Query: 1239 PGTSEHREMEAPG--GPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHD-------GYH 1289 + E+ PG G D+G G GP Q + + DGE G Sbjct: 1088 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143 Query: 1290 RDE---PFGGPPG----SGTPSRGGRSGSNWGRGSNMNSGPP 1324 DE F GPPG G P G G N G GPP Sbjct: 1144 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1185 Score = 228 bits (581), Expect = 3e-59 Identities = 263/860 (30%), Positives = 324/860 (37%), Gaps = 164/860 (19%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 PP G +GPQ PG P G Q Q +P +GPPG +G PG G Sbjct: 635 PPGPKGN--MGPQGEPG-------PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG 685 Query: 634 QMGPQGPPLH---------QGGGGPQGFMGPQGPQGP--------------------PQG 664 G GPP H +G GP G GP G GP G Sbjct: 686 LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 745 Query: 665 LPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPG 724 P + G +G + G GP G GP GP+G +GP G GP G G +G +G G PG Sbjct: 746 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 805 Query: 725 PQGHLGPQGP---PGTQGMQGPPGPRGMQGPPHPHGIQG--GP-GSQGIQGPVSQGPLMG 778 G GP+G PG G G G RG+ G P P G +G GP GS+G +GP + G Sbjct: 806 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865 Query: 779 LNPRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQ 837 + G GPPGP +GP PQG + P+ GP GL GH Q RG +G Sbjct: 866 TS--GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ--RGETGFQGKT 921 Query: 838 GPPPQGSMLGP--PQELRGPPGSQSQQGPP-----QGSLGPPPQGGMQGPPGPQ---GQQ 887 GPP G ++GP P GP G + GPP QG G + G +G PGPQ G+ Sbjct: 922 GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 981 Query: 888 NPA--RGPHPSQGPIPFQQQKTPLLG----DGPRAPFNQEGQ----STGPPPLIPG---- 933 PA RG P + +P Q L G GP P G+ T P +PG Sbjct: 982 GPAGLRG-FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1040 Query: 934 ------LGQQGAQGRIPPLNPGQGPGPNKG-----DSRGPPNHHMGPMSERRHEQSGGPE 982 G++GA G P QGP G GP P + + G P Sbjct: 1041 QGPPGPAGEKGAPGEKGP----QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1096 Query: 983 HGPERGPFRGGQDCRGPPDRRGP--HPDFPDDFSRPDDFHPDKRFGHR----LREFEGRG 1036 +G +G GPP +GP P P FG + R F G Sbjct: 1097 QKGSKGD-KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1155 Query: 1037 GPL-------PQEEKWRRG--GP-GPPFPPDHREFSEGDGRGAARGPPGA-------WEG 1079 GP+ P EK G GP GPP PP R +G +GPPG+ E Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215 Query: 1080 RRPGDERFPRDPEDPRFRGRREESFRRG--APPRHEGRAPPRGRDGFPGPEDFGPEENFD 1137 PG+ P P + G + E +G PP G A P G G PG D GP+ N Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP---GAAGPPGAKGPPG--DDGPKGN-- 1268 Query: 1138 ASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNR--EPGPGHEHF 1195 D G P G+ G+ GG K + D + PGP E Sbjct: 1269 -PGPVGFPGDPGPPGEPGP-AGQDGV-----------GGDKGEDGDPGQPGPPGPSGEAG 1315 Query: 1196 RDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSE 1255 P P R+ +G A PP K GP P GP+ Sbjct: 1316 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGK----TGP--------VGPQGPAG 1363 Query: 1256 DRGGKG-RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFG--GPPG-SGTPSRGGRSGS 1311 G +G RG PGP G + +D P G GPPG G G G Sbjct: 1364 KPGPEGLRGIPGPVGEQGLPGAAG-----------QDGPPGPMGPPGLPGLKGDPGSKGE 1412 Query: 1312 NWGRGSNMNSGPPRRGASRG 1331 G GPP +G Sbjct: 1413 KGHPGLIGLIGPPGEQGEKG 1432 Score = 217 bits (552), Expect = 7e-56 Identities = 221/675 (32%), Positives = 261/675 (38%), Gaps = 161/675 (23%) Query: 573 QPPPSSGTPLLGPQPFPG----QGPMSQI----PQGFQQPHPSQQMPMNMAQMGPPGPQG 624 +P P + GP PG QGP + P+G P +P + Q G G QG Sbjct: 860 KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 919 Query: 625 QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP---QGPP--------QGLPRPQDMHG 673 + PPGP G +GPQGP G G +G GP GP QG P +G P PQ + G Sbjct: 920 KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 979 Query: 674 ---PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG 730 P G++ PG G G QG PG +G GPQG GP G PG +G G GP G G G Sbjct: 980 KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1039 Query: 731 PQGPPGTQGMQGPPGPRGMQGP------------PHPHGIQGGPGSQGIQGPVSQ-GPLM 777 PQGPPG G +G PG +G QGP P P G G PG G +G + + G Sbjct: 1040 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1099 Query: 778 GLNPRGMQGPPGPRENQGP--AP--------------QGMIMGHPPQEMRG-PHPPG--- 817 +G GPPGP QGP AP QGM + RG P PPG Sbjct: 1100 SKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG 1159 Query: 818 --GLLGH----------GPQEMRGPQEIRGMQGPPPQGSMLGPPQEL--------RGPPG 857 GL G GP GP RG QGP GPP + +G PG Sbjct: 1160 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1219 Query: 858 SQSQQGPP--------------QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQ 903 GPP +G GPP G G GP G P P GP+ F Sbjct: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFP 1275 Query: 904 QQKTPLLGDGPRAPFNQEGQS-----------TGPPPLIPGLGQQGAQG-RIPPLNPG-- 949 P G P Q+G GPP G G G R PP G Sbjct: 1276 GDPGP---PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332 Query: 950 --QGPGPNKGDS--RGPPNHHMGPMSERRHEQSGGPEH-----GP--ERG-PFRGGQDCR 997 QG KG++ GPP GP+ + GPE GP E+G P GQD Sbjct: 1333 GRQGEKGAKGEAGAEGPPGK-TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD-- 1389 Query: 998 GPPDRRGPHPDFP----DDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPP 1053 GPP GP P P D S+ + HP G P Q EK RG PG Sbjct: 1390 GPPGPMGP-PGLPGLKGDPGSKGEKGHPGL--------IGLIGPPGEQGEKGDRGLPG-- 1438 Query: 1054 FPPDHREFSEGDGRGAARGPPGA-WEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRH 1112 +G PGA +G PG P P G + +G+ Sbjct: 1439 ----------------TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS---- 1478 Query: 1113 EGRAPPRGRDGFPGP 1127 G A +G G PGP Sbjct: 1479 TGPAGQKGDSGLPGP 1493 Score = 202 bits (513), Expect = 2e-51 Identities = 154/422 (36%), Positives = 185/422 (43%), Gaps = 81/422 (19%) Query: 616 QMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGP------QGFMGPQGPQGPPQGLPRP- 668 Q G G +G+ PPGP G GP G P GG G QG G +G +G +G P P Sbjct: 1097 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA-RGFPGPP 1155 Query: 669 -----QDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPP 723 Q + GP G + G GP+GP GPPGP+G GP G GPQGPPG G +G G Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1215 Query: 724 GPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRG 783 G G G GPPG G+ GP G RG +G P G G PG++G P GP P G Sbjct: 1216 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG--PPGDDGPKGNPGPVG 1273 Query: 784 MQGPPGPRENQGPAPQGMIMGH--------------PPQEMRGPHPPG-----GLLG-HG 823 G PGP GPA Q + G P E P PPG G G G Sbjct: 1274 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1333 Query: 824 PQEMRGPQEIRGMQGPPPQGSMLGP--------PQELRGPPGSQSQQG--------PPQG 867 Q +G + G +GPP + +GP P+ LRG PG +QG P G Sbjct: 1334 RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1393 Query: 868 SLGPPPQGGMQGPPGPQGQQNPAR-----GPHPSQGP-----IPFQQQKTPLLGD----G 913 +GPP G++G PG +G++ GP QG +P Q GD G Sbjct: 1394 PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPG 1453 Query: 914 PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQ-GPGPNKGDS--RGPPNHHMGPM 970 P P G PP +P G QG +G N G GP KGDS GPP GP Sbjct: 1454 PAGPLGPPG-----PPGLP--GPQGPKG-----NKGSTGPAGQKGDSGLPGPPG-SPGPP 1500 Query: 971 SE 972 E Sbjct: 1501 GE 1502 Score = 189 bits (479), Expect = 2e-47 Identities = 136/367 (37%), Positives = 168/367 (45%), Gaps = 47/367 (12%) Query: 584 GPQPFPGQ-GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPL 642 G + FPG GP+ QG P + ++ MGPPGP G P GP G GPQGPP Sbjct: 1147 GARGFPGPPGPIGL--QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1204 Query: 643 HQG---GGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPG--- 694 G G G +G G G GPP G+ P+ G +G PG GP G +GPPG Sbjct: 1205 SVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDG 1264 Query: 695 PQGSSGP---QGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQG 751 P+G+ GP G GP G PGP G G G G G G GPPG G GPPGP G +G Sbjct: 1265 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1324 Query: 752 PPHPHGIQGGPGSQGIQG-------PVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMG 804 PP G +G G +G +G P GP+ P G GP G R GP + + G Sbjct: 1325 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384 Query: 805 HPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQEL-----RGPPGSQ 859 Q+ PPG + G ++G +G +G P ++GPP E RG PG+Q Sbjct: 1385 AAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440 Query: 860 SQQGP--------PQGSLGPP-------PQG--GMQGPPGPQGQQNPARGPHPSQGPIPF 902 G P G LGPP PQG G +G GP GQ+ + P P P P Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1500 Query: 903 QQQKTPL 909 + PL Sbjct: 1501 GEVIQPL 1507 Score = 186 bits (472), Expect = 1e-46 Identities = 135/353 (38%), Positives = 155/353 (43%), Gaps = 47/353 (13%) Query: 583 LGPQPFPG----QGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQ 638 +GP PG QGP G Q P S + + G PG G PPG G GP+ Sbjct: 1179 MGPPGPPGPRGPQGPNGA--DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1236 Query: 639 GPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGS 698 G +G GP G GP G +GPP G P+ GP G PGP G GP G G G Sbjct: 1237 GERGEKGEAGPPGAAGPPGAKGPP-GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1295 Query: 699 SGPQGHMGPQGPPGPQGHIGPQGPP---------GPQGHLGPQGPPGTQGMQGPPGPRGM 749 G G G GPPGP G GP GPP G +G G +G G G +GPPG G Sbjct: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQE 809 GP P G G G +GI GPV + L G G GPPGP GP + G P + Sbjct: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPG--AAGQDGPPGP---MGPPGLPGLKGDPGSK 1410 Query: 810 MRGPHPPGGLLG----HGPQEMRGPQEIRGMQGPP----------PQGSMLGPPQELRGP 855 HP GL+G G Q +G + + G QG P P G LGPP GP Sbjct: 1411 GEKGHP--GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP-LGPP----GP 1463 Query: 856 PGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQK 906 PG QGP +GS GP Q G G PGP G P P P+P K Sbjct: 1464 PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP---PGEVIQPLPILSSK 1513 Score = 132 bits (332), Expect = 2e-30 Identities = 93/265 (35%), Positives = 108/265 (40%), Gaps = 54/265 (20%) Query: 575 PPSSGTPLLGPQP--FPGQ-GPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG 630 PP P P P FPG GP + P G + + Q GPPGP G+ PPG Sbjct: 1259 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1318 Query: 631 PQGQMGP------------QGPPLHQGGGGPQGFMGPQGPQGPP--------QGLPRPQD 670 P G+ GP +G G GP G GP GPQGP +G+P P Sbjct: 1319 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1378 Query: 671 MHGPQGMQRHPGPHGPLGPQG------------------------PPGPQGSSGPQGHMG 706 G G GP GP+GP G PPG QG G +G G Sbjct: 1379 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438 Query: 707 PQGPPGPQGH------IGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQG 760 QG PG +G GP GPPGP G GPQGP G +G GP G +G G P P G G Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498 Query: 761 GPGSQGIQGPVSQGPLMGLNPRGMQ 785 PG P+ + GMQ Sbjct: 1499 PPGEVIQPLPILSSKKTRRHTEGMQ 1523 Score = 90.9 bits (224), Expect = 7e-18 Identities = 155/571 (27%), Positives = 196/571 (34%), Gaps = 97/571 (16%) Query: 806 PPQEMRGPHPPG-------GLLGHGPQEMRGPQE----------IRGMQGPPPQGSMLGP 848 PP E GP P + GHG +G + + G GP ++GP Sbjct: 357 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 416 Query: 849 P--QELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP-IPFQQQ 905 P Q GPPG +GPP G G P G+ GPPG G S+GP I Q+ Sbjct: 417 PGLQGPTGPPGDPGDRGPP-GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA 475 Query: 906 KTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNH 965 + + R GPP G G GR P+ G G KG+S P Sbjct: 476 QAQAILQQARIALR------GPP------GPMGLTGRPGPVG-GPGSSGAKGESGDP--- 519 Query: 966 HMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRF 1025 GP R + GP P + G RG P G D Sbjct: 520 --GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD----------------- 560 Query: 1026 GHRLREFEGRGG-PLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRP-G 1083 R F+G G P + + RG GPP PP DG RG PG R G Sbjct: 561 ----RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 616 Query: 1084 DERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDF-GPEENFDA-SEE 1141 P P P G +G +G P G+ G PGP+ GP+ E+ Sbjct: 617 PRGTPGAPGQPGMAGVDGPPGPKGNMGP-QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 675 Query: 1142 AARGRD-LRGR-GRGTPRG--------GRKGLL--PTPDEFPRFEGGRKPDSWDGNRE-P 1188 +G+ L G G P G G KG L P P + G R DG R Sbjct: 676 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK 735 Query: 1189 GPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGP-GTSEHREM 1247 G E D P G +R ++ + PR DGP G Sbjct: 736 GSKGEKGED----GFPGFKGDMGLKGDRG------EVGQIGPRGE---DGPEGPKGRAGP 782 Query: 1248 EAPGGPSEDRGGKGR-GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRG 1306 GPS G KG+ G PG + G S G + ++ G +G P Sbjct: 783 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK--GARGVAGKPGPR 840 Query: 1307 GRSGSNWGRGSNMNSGPPRRGASRG--GGRG 1335 G+ G RGS GP + +G GG G Sbjct: 841 GQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 871 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 247 bits (630), Expect = 6e-65 Identities = 246/770 (31%), Positives = 302/770 (39%), Gaps = 167/770 (21%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 GPPGP G G G++GP+G P G GP+G +GP+G G P G P + GP Sbjct: 622 GPPGPPGDDGMRGEDGEIGPRGLP---GEAGPRGLLGPRGTPGAP-GQPGMAGVDGP--- 674 Query: 678 QRHPGPHGPLGPQGPPGP---QGSSGPQGHMGPQGPPGPQGHIGPQGPP---------GP 725 PGP G +GPQG PGP QG+ GPQG GPQGP GP G GPQG P GP Sbjct: 675 ---PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 731 Query: 726 QGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ------------ 773 GH G +G G +G GPPGP+G G P P G++G G +G++G + Sbjct: 732 PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 791 Query: 774 -------GPLMGLNPRGMQGPPGPRENQG----PAPQGM-----------IMGHPPQEMR 811 G + + PRG GP GP+ G P P G + G+P ++ Sbjct: 792 MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ-- 849 Query: 812 GPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGP 871 GP G G G + RG+ G P GP GP GS+ +G P G GP Sbjct: 850 GPKGSTGFPGF--PGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARG-PTGKPGP 902 Query: 872 PPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLI 931 G GPPGP G+ RGP QGP+ F K GP P ++G P Sbjct: 903 KGTSGGDGPPGPPGE----RGPQGPQGPVGFPGPK------GPPGPPGKDGL-----PGH 947 Query: 932 PG-LGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPF 990 PG G+ G QG+ P PG GP P GP+ ER H GP Sbjct: 948 PGQRGETGFQGKTGPPGPGGVVGPQ------GPTGETGPIGERGHPGPPGPP-------- 993 Query: 991 RGGQDCRGPPDRRGPHPD-FPDDFSRPDDFHPDKRFGHRLREFEG-RGGPLPQEEKWRRG 1048 G Q G + G D P S D LR F G RG P Q +G Sbjct: 994 -GEQGLPGAAGKEGAKGDPGPQGISGKDG-------PAGLRGFPGERGLPGAQGAPGLKG 1045 Query: 1049 GPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGA 1108 G GP PP G GP G RPG P+ P P + +GA Sbjct: 1046 GEGPQGPPGPVGSPGERGSAGTAGPIGL--PGRPG----PQGPPGP--------AGEKGA 1091 Query: 1109 PPRHEGRAPPRGRDGFPGPEDF-GPEENFDASEEAARGRDLRGRGRGTPRG--GRKGLLP 1165 P +G P GRDG GP GP + E ++ G+ +G G G Sbjct: 1092 -PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG--- 1147 Query: 1166 TPDEFPRFEGG-RKPDSWDGNREPGP----------GHEHFRDTPRPDHPPHDGHSPASR 1214 P P +G P G+ EPGP G E R P P P Sbjct: 1148 -PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP---------- 1196 Query: 1215 ERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKS 1274 LQG+ PP ++ + G P GP RG +G G Q P S Sbjct: 1197 ---IGLQGLPG---PPGEKGENGDVGPM------GPPGPPGPRGPQGPNGADGPQGPPGS 1244 Query: 1275 GRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 S GE + EP G G P G G RG +GPP Sbjct: 1245 VGSVGGVGE------KGEP-GEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1287 Score = 243 bits (619), Expect = 1e-63 Identities = 241/757 (31%), Positives = 300/757 (39%), Gaps = 140/757 (18%) Query: 592 GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQG 651 GP Q +G P S+ + GP G G PPGP G+ GPQGP GP G Sbjct: 877 GPRGQ--RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ------GPVG 928 Query: 652 FMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGP---LGPQGPPGPQGSSGPQGHMG 706 F GP+GP GPP GLP G G Q GP GP +GPQGP G G G +GH G Sbjct: 929 FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPG 988 Query: 707 PQGPPGPQGHIGPQGPPGPQGHLGPQG---PPGTQGMQGPPGPRGMQGPPHPHGIQGGPG 763 P GPPG QG G G G +G GPQG G G++G PG RG+ G G++GG G Sbjct: 989 PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1048 Query: 764 SQGIQGPVS----QGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGL 819 QG GPV +G P G+ G PGP+ GPA + G P + +GP P G Sbjct: 1049 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE---KGAPGE--KGPQGPAGR 1103 Query: 820 LG-HGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP-----QGSLGPPP 873 G GP + GP G G +G P + +G G + + GPP QG +G P Sbjct: 1104 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ-KGSKGDKGENGPPGPPGLQGPVGAPG 1162 Query: 874 QGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQS--TGP--PP 929 G G PGP+GQQ G +G F P+ G P ++G++ GP PP Sbjct: 1163 IAGGDGEPGPRGQQGMF-GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221 Query: 930 LIPG-LGQQGAQGRIPPLNP----------GQGPGPNKGDSRGPPNHHM--GPMSERRHE 976 PG G QG G P P G+ P + + GPP GP ER + Sbjct: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281 Query: 977 QSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRG 1036 GP G +GPP GP + P P D P G Sbjct: 1282 GEAGPPGAA------GPPGAKGPPGDDGPKGN-PGPVGFPGDPGPP-----------GEP 1323 Query: 1037 GPLPQE----EKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAW--EGRRPGDERFPRD 1090 GP Q+ +K G PG P PP + G RGPPGA EGR+ G+ Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ-GE------ 1376 Query: 1091 PEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFG--PEENFDASEEAARGRDL 1148 +G + E+ G PP G P+G G PGPE P + A G+D Sbjct: 1377 ------KGAKGEAGAEG-PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD- 1428 Query: 1149 RGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDG 1208 G P G P P +G +PG E HP G Sbjct: 1429 ---GPPGPMG--------PPGLPGLKG-----------DPGSKGEK-------GHPGLIG 1459 Query: 1209 H-SPASRERSSSLQGMDMASLPPRKRPWHDG-PGTSEHREMEAPGGPSEDRGGKGRGGPG 1266 P + +G+ P G PG + P GP G G GP Sbjct: 1460 LIGPPGEQGEKGDRGL----------PGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGP- 1508 Query: 1267 PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTP 1303 + PK + S+ G D GPPGS P Sbjct: 1509 ---QGPKGNKGSTGPA----GQKGDSGLPGPPGSPGP 1538 Score = 232 bits (592), Expect = 2e-60 Identities = 255/822 (31%), Positives = 315/822 (38%), Gaps = 157/822 (19%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 GP GP G PPG QG GP G P +G G G G G GPP + +G G Sbjct: 445 GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS 504 Query: 678 QRHP--------------------GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHI 717 + GP GP+G G PGP G G G G G PGPQG Sbjct: 505 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 564 Query: 718 GPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLM 777 G QGPPGP G G +G PG G +G PG G +G G+ G PG +G +G Sbjct: 565 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG-------- 616 Query: 778 GLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMRGPQEIRGM 836 RG QGPPGP + G + +G P+ + G P GLLG G G + G+ Sbjct: 617 ---ERGPQGPPGPPGDDGMRGEDGEIG--PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 671 Query: 837 QGPP-PQGSMLGPPQELRGPPGSQSQQGP-----PQGSLGPP----PQG--------GMQ 878 GPP P+G+M PQ GPPG Q GP PQG +GPP PQG G Sbjct: 672 DGPPGPKGNM--GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729 Query: 879 GPPGPQGQQNP-----ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ--STGPPPLI 931 GPPG G++ A GP QGPI + + DG R +G+ G P Sbjct: 730 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789 Query: 932 PGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFR 991 +G +G +G + + P GP R P GP Q+G E+G Sbjct: 790 GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG-----QAG------EKGKL- 837 Query: 992 GGQDCRGPPDRRGP-----HPDFP----DDFSRPDDFHPDKRFGHR----LREFEGRGGP 1038 G G P R+GP P FP + +R P R G R R G GP Sbjct: 838 GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR-GQRGPTGPRGSRGARGP 896 Query: 1039 LPQE-EKWRRGGPGPPFPPDHR--EFSEGD-GRGAARGPPGAWEGRRPGDERFPRDP--- 1091 + K GG GPP PP R + +G G +GPPG PG + P P Sbjct: 897 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP-----PGKDGLPGHPGQR 951 Query: 1092 EDPRFRGRREESFRRG--APPRHEGRAPPRGRDGFPGPEDFGPEENFD--ASEEAARG-- 1145 + F+G+ G P G P G G PGP E+ A +E A+G Sbjct: 952 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011 Query: 1146 --RDLRGRG-----RGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDT 1198 + + G+ RG P G +G LP P +GG P G PG T Sbjct: 1012 GPQGISGKDGPAGLRGFP--GERG-LPGAQGAPGLKGGEGPQGPPG-PVGSPGERGSAGT 1067 Query: 1199 ---------PRPDHPPHDG-----------HSPASRERSSSLQGMDMASLPPRKRPWHDG 1238 P P PP PA R+ G+ P P DG Sbjct: 1068 AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP-GPAGPAGSPGEDG 1126 Query: 1239 PGTSEHREMEAPG--GPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHD-------GYH 1289 + E+ PG G D+G G GP Q + + DGE G Sbjct: 1127 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182 Query: 1290 RDE---PFGGPPG----SGTPSRGGRSGSNWGRGSNMNSGPP 1324 DE F GPPG G P G G N G GPP Sbjct: 1183 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1224 Score = 228 bits (581), Expect = 3e-59 Identities = 263/860 (30%), Positives = 324/860 (37%), Gaps = 164/860 (19%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 PP G +GPQ PG P G Q Q +P +GPPG +G PG G Sbjct: 674 PPGPKGN--MGPQGEPG-------PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG 724 Query: 634 QMGPQGPPLH---------QGGGGPQGFMGPQGPQGP--------------------PQG 664 G GPP H +G GP G GP G GP G Sbjct: 725 LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 784 Query: 665 LPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPG 724 P + G +G + G GP G GP GP+G +GP G GP G G +G +G G PG Sbjct: 785 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 844 Query: 725 PQGHLGPQGP---PGTQGMQGPPGPRGMQGPPHPHGIQG--GP-GSQGIQGPVSQGPLMG 778 G GP+G PG G G G RG+ G P P G +G GP GS+G +GP + G Sbjct: 845 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904 Query: 779 LNPRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQ 837 + G GPPGP +GP PQG + P+ GP GL GH Q RG +G Sbjct: 905 TS--GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQ--RGETGFQGKT 960 Query: 838 GPPPQGSMLGP--PQELRGPPGSQSQQGPP-----QGSLGPPPQGGMQGPPGPQ---GQQ 887 GPP G ++GP P GP G + GPP QG G + G +G PGPQ G+ Sbjct: 961 GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1020 Query: 888 NPA--RGPHPSQGPIPFQQQKTPLLG----DGPRAPFNQEGQ----STGPPPLIPG---- 933 PA RG P + +P Q L G GP P G+ T P +PG Sbjct: 1021 GPAGLRG-FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1079 Query: 934 ------LGQQGAQGRIPPLNPGQGPGPNKG-----DSRGPPNHHMGPMSERRHEQSGGPE 982 G++GA G P QGP G GP P + + G P Sbjct: 1080 QGPPGPAGEKGAPGEKGP----QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1135 Query: 983 HGPERGPFRGGQDCRGPPDRRGP--HPDFPDDFSRPDDFHPDKRFGHR----LREFEGRG 1036 +G +G GPP +GP P P FG + R F G Sbjct: 1136 QKGSKGD-KGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1194 Query: 1037 GPL-------PQEEKWRRG--GP-GPPFPPDHREFSEGDGRGAARGPPGA-------WEG 1079 GP+ P EK G GP GPP PP R +G +GPPG+ E Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254 Query: 1080 RRPGDERFPRDPEDPRFRGRREESFRRG--APPRHEGRAPPRGRDGFPGPEDFGPEENFD 1137 PG+ P P + G + E +G PP G A P G G PG D GP+ N Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP---GAAGPPGAKGPPG--DDGPKGN-- 1307 Query: 1138 ASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNR--EPGPGHEHF 1195 D G P G+ G+ GG K + D + PGP E Sbjct: 1308 -PGPVGFPGDPGPPGEPGP-AGQDGV-----------GGDKGEDGDPGQPGPPGPSGEAG 1354 Query: 1196 RDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSE 1255 P P R+ +G A PP K GP P GP+ Sbjct: 1355 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGK----TGP--------VGPQGPAG 1402 Query: 1256 DRGGKG-RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFG--GPPG-SGTPSRGGRSGS 1311 G +G RG PGP G + +D P G GPPG G G G Sbjct: 1403 KPGPEGLRGIPGPVGEQGLPGAAG-----------QDGPPGPMGPPGLPGLKGDPGSKGE 1451 Query: 1312 NWGRGSNMNSGPPRRGASRG 1331 G GPP +G Sbjct: 1452 KGHPGLIGLIGPPGEQGEKG 1471 Score = 217 bits (552), Expect = 7e-56 Identities = 221/675 (32%), Positives = 261/675 (38%), Gaps = 161/675 (23%) Query: 573 QPPPSSGTPLLGPQPFPG----QGPMSQI----PQGFQQPHPSQQMPMNMAQMGPPGPQG 624 +P P + GP PG QGP + P+G P +P + Q G G QG Sbjct: 899 KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 958 Query: 625 QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP---QGPP--------QGLPRPQDMHG 673 + PPGP G +GPQGP G G +G GP GP QG P +G P PQ + G Sbjct: 959 KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1018 Query: 674 ---PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG 730 P G++ PG G G QG PG +G GPQG GP G PG +G G GP G G G Sbjct: 1019 KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1078 Query: 731 PQGPPGTQGMQGPPGPRGMQGP------------PHPHGIQGGPGSQGIQGPVSQ-GPLM 777 PQGPPG G +G PG +G QGP P P G G PG G +G + + G Sbjct: 1079 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1138 Query: 778 GLNPRGMQGPPGPRENQGP--AP--------------QGMIMGHPPQEMRG-PHPPG--- 817 +G GPPGP QGP AP QGM + RG P PPG Sbjct: 1139 SKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG 1198 Query: 818 --GLLGH----------GPQEMRGPQEIRGMQGPPPQGSMLGPPQEL--------RGPPG 857 GL G GP GP RG QGP GPP + +G PG Sbjct: 1199 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1258 Query: 858 SQSQQGPP--------------QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQ 903 GPP +G GPP G G GP G P P GP+ F Sbjct: 1259 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP----GPVGFP 1314 Query: 904 QQKTPLLGDGPRAPFNQEGQS-----------TGPPPLIPGLGQQGAQG-RIPPLNPG-- 949 P G P Q+G GPP G G G R PP G Sbjct: 1315 GDPGP---PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371 Query: 950 --QGPGPNKGDS--RGPPNHHMGPMSERRHEQSGGPEH-----GP--ERG-PFRGGQDCR 997 QG KG++ GPP GP+ + GPE GP E+G P GQD Sbjct: 1372 GRQGEKGAKGEAGAEGPPGK-TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD-- 1428 Query: 998 GPPDRRGPHPDFP----DDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPP 1053 GPP GP P P D S+ + HP G P Q EK RG PG Sbjct: 1429 GPPGPMGP-PGLPGLKGDPGSKGEKGHPGL--------IGLIGPPGEQGEKGDRGLPG-- 1477 Query: 1054 FPPDHREFSEGDGRGAARGPPGA-WEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRH 1112 +G PGA +G PG P P G + +G+ Sbjct: 1478 ----------------TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS---- 1517 Query: 1113 EGRAPPRGRDGFPGP 1127 G A +G G PGP Sbjct: 1518 TGPAGQKGDSGLPGP 1532 Score = 202 bits (513), Expect = 2e-51 Identities = 154/422 (36%), Positives = 185/422 (43%), Gaps = 81/422 (19%) Query: 616 QMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGP------QGFMGPQGPQGPPQGLPRP- 668 Q G G +G+ PPGP G GP G P GG G QG G +G +G +G P P Sbjct: 1136 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA-RGFPGPP 1194 Query: 669 -----QDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPP 723 Q + GP G + G GP+GP GPPGP+G GP G GPQGPPG G +G G Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK 1254 Query: 724 GPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRG 783 G G G GPPG G+ GP G RG +G P G G PG++G P GP P G Sbjct: 1255 GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG--PPGDDGPKGNPGPVG 1312 Query: 784 MQGPPGPRENQGPAPQGMIMGH--------------PPQEMRGPHPPG-----GLLG-HG 823 G PGP GPA Q + G P E P PPG G G G Sbjct: 1313 FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1372 Query: 824 PQEMRGPQEIRGMQGPPPQGSMLGP--------PQELRGPPGSQSQQG--------PPQG 867 Q +G + G +GPP + +GP P+ LRG PG +QG P G Sbjct: 1373 RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1432 Query: 868 SLGPPPQGGMQGPPGPQGQQNPAR-----GPHPSQGP-----IPFQQQKTPLLGD----G 913 +GPP G++G PG +G++ GP QG +P Q GD G Sbjct: 1433 PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPG 1492 Query: 914 PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQ-GPGPNKGDS--RGPPNHHMGPM 970 P P G PP +P G QG +G N G GP KGDS GPP GP Sbjct: 1493 PAGPLGPPG-----PPGLP--GPQGPKG-----NKGSTGPAGQKGDSGLPGPPG-SPGPP 1539 Query: 971 SE 972 E Sbjct: 1540 GE 1541 Score = 189 bits (479), Expect = 2e-47 Identities = 136/367 (37%), Positives = 168/367 (45%), Gaps = 47/367 (12%) Query: 584 GPQPFPGQ-GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPL 642 G + FPG GP+ QG P + ++ MGPPGP G P GP G GPQGPP Sbjct: 1186 GARGFPGPPGPIGL--QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG 1243 Query: 643 HQG---GGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPG--- 694 G G G +G G G GPP G+ P+ G +G PG GP G +GPPG Sbjct: 1244 SVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDG 1303 Query: 695 PQGSSGP---QGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQG 751 P+G+ GP G GP G PGP G G G G G G GPPG G GPPGP G +G Sbjct: 1304 PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRG 1363 Query: 752 PPHPHGIQGGPGSQGIQG-------PVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMG 804 PP G +G G +G +G P GP+ P G GP G R GP + + G Sbjct: 1364 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423 Query: 805 HPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQEL-----RGPPGSQ 859 Q+ PPG + G ++G +G +G P ++GPP E RG PG+Q Sbjct: 1424 AAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479 Query: 860 SQQGP--------PQGSLGPP-------PQG--GMQGPPGPQGQQNPARGPHPSQGPIPF 902 G P G LGPP PQG G +G GP GQ+ + P P P P Sbjct: 1480 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1539 Query: 903 QQQKTPL 909 + PL Sbjct: 1540 GEVIQPL 1546 Score = 186 bits (472), Expect = 1e-46 Identities = 135/353 (38%), Positives = 155/353 (43%), Gaps = 47/353 (13%) Query: 583 LGPQPFPG----QGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQ 638 +GP PG QGP G Q P S + + G PG G PPG G GP+ Sbjct: 1218 MGPPGPPGPRGPQGPNGA--DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1275 Query: 639 GPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGS 698 G +G GP G GP G +GPP G P+ GP G PGP G GP G G G Sbjct: 1276 GERGEKGEAGPPGAAGPPGAKGPP-GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGD 1334 Query: 699 SGPQGHMGPQGPPGPQGHIGPQGPP---------GPQGHLGPQGPPGTQGMQGPPGPRGM 749 G G G GPPGP G GP GPP G +G G +G G G +GPPG G Sbjct: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQE 809 GP P G G G +GI GPV + L G G GPPGP GP + G P + Sbjct: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPG--AAGQDGPPGP---MGPPGLPGLKGDPGSK 1449 Query: 810 MRGPHPPGGLLG----HGPQEMRGPQEIRGMQGPP----------PQGSMLGPPQELRGP 855 HP GL+G G Q +G + + G QG P P G LGPP GP Sbjct: 1450 GEKGHP--GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP-LGPP----GP 1502 Query: 856 PGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQK 906 PG QGP +GS GP Q G G PGP G P P P+P K Sbjct: 1503 PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP---PGEVIQPLPILSSK 1552 Score = 132 bits (332), Expect = 2e-30 Identities = 93/265 (35%), Positives = 108/265 (40%), Gaps = 54/265 (20%) Query: 575 PPSSGTPLLGPQP--FPGQ-GPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG 630 PP P P P FPG GP + P G + + Q GPPGP G+ PPG Sbjct: 1298 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1357 Query: 631 PQGQMGP------------QGPPLHQGGGGPQGFMGPQGPQGPP--------QGLPRPQD 670 P G+ GP +G G GP G GP GPQGP +G+P P Sbjct: 1358 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1417 Query: 671 MHGPQGMQRHPGPHGPLGPQG------------------------PPGPQGSSGPQGHMG 706 G G GP GP+GP G PPG QG G +G G Sbjct: 1418 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477 Query: 707 PQGPPGPQGH------IGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQG 760 QG PG +G GP GPPGP G GPQGP G +G GP G +G G P P G G Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537 Query: 761 GPGSQGIQGPVSQGPLMGLNPRGMQ 785 PG P+ + GMQ Sbjct: 1538 PPGEVIQPLPILSSKKTRRHTEGMQ 1562 Score = 90.9 bits (224), Expect = 7e-18 Identities = 155/571 (27%), Positives = 196/571 (34%), Gaps = 97/571 (16%) Query: 806 PPQEMRGPHPPG-------GLLGHGPQEMRGPQE----------IRGMQGPPPQGSMLGP 848 PP E GP P + GHG +G + + G GP ++GP Sbjct: 396 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 455 Query: 849 P--QELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP-IPFQQQ 905 P Q GPPG +GPP G G P G+ GPPG G S+GP I Q+ Sbjct: 456 PGLQGPTGPPGDPGDRGPP-GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA 514 Query: 906 KTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNH 965 + + R GPP G G GR P+ G G KG+S P Sbjct: 515 QAQAILQQARIALR------GPP------GPMGLTGRPGPVG-GPGSSGAKGESGDP--- 558 Query: 966 HMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRF 1025 GP R + GP P + G RG P G D Sbjct: 559 --GPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD----------------- 599 Query: 1026 GHRLREFEGRGG-PLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRP-G 1083 R F+G G P + + RG GPP PP DG RG PG R G Sbjct: 600 ----RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG 655 Query: 1084 DERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDF-GPEENFDA-SEE 1141 P P P G +G +G P G+ G PGP+ GP+ E+ Sbjct: 656 PRGTPGAPGQPGMAGVDGPPGPKGNMGP-QGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 714 Query: 1142 AARGRD-LRGR-GRGTPRG--------GRKGLL--PTPDEFPRFEGGRKPDSWDGNRE-P 1188 +G+ L G G P G G KG L P P + G R DG R Sbjct: 715 GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK 774 Query: 1189 GPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGP-GTSEHREM 1247 G E D P G +R ++ + PR DGP G Sbjct: 775 GSKGEKGED----GFPGFKGDMGLKGDRG------EVGQIGPRGE---DGPEGPKGRAGP 821 Query: 1248 EAPGGPSEDRGGKGR-GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRG 1306 GPS G KG+ G PG + G S G + ++ G +G P Sbjct: 822 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK--GARGVAGKPGPR 879 Query: 1307 GRSGSNWGRGSNMNSGPPRRGASRG--GGRG 1335 G+ G RGS GP + +G GG G Sbjct: 880 GQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 910 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 243 bits (620), Expect = 9e-64 Identities = 243/765 (31%), Positives = 280/765 (36%), Gaps = 150/765 (19%) Query: 575 PPSSGTPLLGPQPFPGQGPMSQIP-QGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 PP S P P GP Q GF P + P + G PG G PPG G Sbjct: 553 PPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNG 612 Query: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPP 693 + GPQGPP G GG +G GP GPQG QGLP G G PGP G G G P Sbjct: 613 ETGPQGPPGPTGPGGDKGDTGPPGPQG-LQGLPGTGGPPGENGKPGEPGPKGDAGAPGAP 671 Query: 694 GPQGSSGPQGHMGP---QGPPGPQGHIGPQGPPGPQGHLGPQGPP---GTQGMQGPPGPR 747 G +G +G G GP G PG +G GP GP G +G GP GPP GT G+QG PG R Sbjct: 672 GGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGER 731 Query: 748 GMQGPPHPHGIQGGPGSQGIQG-PVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHP 806 G G P P G +G PG G G P GP P G GPPGP G +G G P Sbjct: 732 GGLGSPGPKGDKGEPGGPGADGVPGKDGP---RGPTGPIGPPGPAGQPGDKGEGGAPGLP 788 Query: 807 PQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQ 866 + GP G G GP G G P Q G E RG PG + + GPP Sbjct: 789 --GIAGPRGSPGERGE-----TGPPGPAGFPGAPGQNGEPGGKGE-RGAPGEKGEGGPP- 839 Query: 867 GSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTG 926 G GPP G GPPGPQG + RG G F + G P G + G Sbjct: 840 GVAGPPGGSGPAGPPGPQGVKG-ERGSPGGPGAAGFPGAR------GLPGPPGSNG-NPG 891 Query: 927 PPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPE 986 PP G G+ G+ P P G P G E+ + GP P Sbjct: 892 PP------GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAP- 944 Query: 987 RGP-----FRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQ 1041 GP G + GPP GP RG P PQ Sbjct: 945 -GPLGIAGITGARGLAGPPGMPGP-----------------------------RGSPGPQ 974 Query: 1042 EEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPG----------AWEGRR---PGDERFP 1088 K G PG +G RGPPG A E R PG + P Sbjct: 975 GVKGESGKPG------------ANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLP 1022 Query: 1089 RDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDL 1148 P +G R E+ GAP G G PGP P A + RG Sbjct: 1023 GRDGSPGGKGDRGENGSPGAP----------GAPGHPGP----PGPVGPAGKSGDRGESG 1068 Query: 1149 RGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDG 1208 G P G G P P+ G K ++ + GH F P P Sbjct: 1069 PAGPAGAP--GPAGSRGAPG--PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP--- 1121 Query: 1209 HSPASRERSSSLQGMDMASLPPRKRPWHDGP----GTSEHREMEAPGGPSEDRGGKG-RG 1263 PA ++ + G PR GP GTS H P GP +RG +G G Sbjct: 1122 -GPAGQQGAIGSPG----PAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG 1176 Query: 1264 GPG-PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGG 1307 PG P Q P GPPG+ P GG Sbjct: 1177 SPGHPGQPGPP----------------------GPPGAPGPCCGG 1199 Score = 240 bits (613), Expect = 6e-63 Identities = 248/780 (31%), Positives = 297/780 (38%), Gaps = 101/780 (12%) Query: 584 GPQPFPGQ-GPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPP 641 GP PG+ GP + G P + P G PG +G PG G G GPP Sbjct: 495 GPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPP 554 Query: 642 LHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSS 699 QG G G GP GP+G P G P P+ G G G G GPQGPPG G + Sbjct: 555 GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET 614 Query: 700 GPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQ 759 GPQG GP GP G +G GP GP G QG G GPPG G G PGP+G G P G + Sbjct: 615 GPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK 674 Query: 760 GGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGL 819 G G+ G +GP GL RG GPPGP +G A GP P G Sbjct: 675 GDAGAPGERGPPGLAGAPGL--RGGAGPPGPEGGKGAA--------------GPPGPPGA 718 Query: 820 LGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQG 879 G G+QG P + LG P GP G + + G P G+ G P + G +G Sbjct: 719 AG-----------TPGLQGMPGERGGLGSP----GPKGDKGEPGGP-GADGVPGKDGPRG 762 Query: 880 PPGPQGQQNPARGP-HPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPP-----PLIPG 933 P GP G PA P +G P P + GPR + G+ TGPP P PG Sbjct: 763 PTGPIGPPGPAGQPGDKGEGGAP----GLPGIA-GPRGSPGERGE-TGPPGPAGFPGAPG 816 Query: 934 L-GQQGAQG-RIPPLNPGQGPGPNKGDSRGPPNHH--MGPMSERRHEQSGGPEHGPERGP 989 G+ G +G R P G+G P GPP GP + + G GP Sbjct: 817 QNGEPGGKGERGAPGEKGEGGPPGVA---GPPGGSGPAGPPGPQGVKGERGSPGGPGAAG 873 Query: 990 FRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHR-LREFEGRGGPLPQE----EK 1044 F G + GPP G +P P P P G+ G GP EK Sbjct: 874 FPGARGLPGPPGSNG-NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEK 932 Query: 1045 WRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGR-RPGDERFPRDPEDPRFRGRREES 1103 G GPP P + G GPPG R PG + + P G E Sbjct: 933 GSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGE- 991 Query: 1104 FRRGAP-----PRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRG 1158 RG P P G A GRDG PG + P + + RG + G P Sbjct: 992 --RGPPGPQGLPGLAGTAGEPGRDGNPGSDGL-PGRDGSPGGKGDRGENGSPGAPGAP-- 1046 Query: 1159 GRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSS 1218 G G P P + G + +S PG R P P P D R ++ Sbjct: 1047 GHPG--PPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG-AA 1103 Query: 1219 SLQGMDMASLPPRKRPWHDGPGTSEHREMEAPG--GPSEDRGGKGRGGP-GPAQRVPKSG 1275 ++G R + PG APG GP+ +G G GP GP V SG Sbjct: 1104 GIKG---------HRGFPGNPG--------APGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146 Query: 1276 RSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRG 1335 H G P G P G G GS G GPP GG G Sbjct: 1147 PPGKDGTSGHPG-----PIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVG 1201 Score = 231 bits (590), Expect = 3e-60 Identities = 257/834 (30%), Positives = 299/834 (35%), Gaps = 152/834 (18%) Query: 619 PPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP---QGLPRPQDMHGPQ 675 PP QG P GP+G GP G P G G G G G GPP + P + PQ Sbjct: 98 PPNGQG---PQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQ 154 Query: 676 -------------GMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGP 722 G+ +PGP GP GP GPPG G G G G QGPPG G GP GP Sbjct: 155 YDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGP 214 Query: 723 PGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN-P 781 PGP G +GP GP G G G PG G +G P P GI+G G G G G N Sbjct: 215 PGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGE 274 Query: 782 RGMQGPPG-------PRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIR 834 +G G PG P EN P P G G P + R P PG G RG Sbjct: 275 KGETGAPGLKGENGLPGENGAPGPMGP-RGAPGERGR-PGLPGAAGARGNDGARGSDGQP 332 Query: 835 GMQGPPPQGSMLGPP--QELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGP------- 883 G GPP G P + GP GS G P +G GP G QGPPGP Sbjct: 333 GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSP 392 Query: 884 --QGQQNP-----------ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPL 930 +G+ P ARGP P P P L G P + G P P Sbjct: 393 GGKGEMGPAGIPGAPGLMGARGP-----PGPAGANGAPGLRGGAGEP-GKNGAKGEPGPR 446 Query: 931 -------IPGL-GQQGAQGRI-PPLNPGQGPGPNKGDSRGPPNH-----------HMGPM 970 IPG+ G +G G+ P PG P RG P GP Sbjct: 447 GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPA 506 Query: 971 SERRHEQSGGPEHG---PERGPFRGGQDCRGPP--------DRRGPHPDFPDDFSRPDDF 1019 ER GP P R GG RG P D + P + RP Sbjct: 507 GERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPP 566 Query: 1020 HPDKRFGH-RLREFEG----RGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPP 1074 P G + F G G P E+ GGPGP PP +G +GPP Sbjct: 567 GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK------NGETGPQGPP 620 Query: 1075 GAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGR---APPRGRDGFPGPEDFG 1131 G PG ++ P P+ + G PP G+ P+G G PG Sbjct: 621 GP---TGPGGDKGDTGPPGPQ---GLQGLPGTGGPPGENGKPGEPGPKGDAGAPG----A 670 Query: 1132 PEENFDASEEAARG-------RDLR-GRGRGTPRGGR--------KGLLPTP--DEFPRF 1173 P DA RG LR G G P GG+ G TP P Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE 730 Query: 1174 EGGRKPDSWDGNR-EPG-------PGHEHFRDTPRPDHPPHDGHSPASRERSSS--LQGM 1223 GG G++ EPG PG + R P PP P + + L G+ Sbjct: 731 RGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI 790 Query: 1224 DMASLPPRKRPWHDGPGTS----EHREMEAPGGPSE--DRGGKGRGGPGPAQRVPKSGRS 1277 P +R PG + + PGG E G KG GGP P Sbjct: 791 AGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGP 850 Query: 1278 SSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 + G R P GGP +G P G G GSN N GPP S G Sbjct: 851 AGPPGPQGVKGERGSP-GGPGAAGFPGARGLPGP---PGSNGNPGPPGPSGSPG 900 Score = 229 bits (584), Expect = 1e-59 Identities = 253/814 (31%), Positives = 310/814 (38%), Gaps = 129/814 (15%) Query: 575 PPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG--- 630 P +G P +GP+ PG+ +P G + + Q GPPGP G PG Sbjct: 290 PGENGAPGPMGPRGAPGERGRPGLP-GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPG 348 Query: 631 ------PQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPG 682 P G G G P +G GPQG G QGP GPP G P + GP G+ PG Sbjct: 349 AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGI---PG 405 Query: 683 PHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG--- 739 G +G +GPPGP G++G G G G PG G G GP G +G G G PG +G Sbjct: 406 APGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDG 465 Query: 740 MQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVS----QGPLMGLNPRGMQGPPGPRENQG 795 G PG G G P G +G PG +G GP +GP RG GP GPR G Sbjct: 466 KDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPA---GERGAPGPAGPRGAAG 522 Query: 796 PAPQGMIMGHPPQEMRG-PHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRG 854 + + G P MRG P PGG G G Q G GPP G P + G Sbjct: 523 EPGRDGVPGGPG--MRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVM-G 579 Query: 855 PPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD 912 PG + G P G G P G QGPPG G+ P P P+ GP + GD Sbjct: 580 FPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT-GPGGDK-------GD 631 Query: 913 -GPRAPFNQEG-QSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGP--NKGDSRGPPNHHMG 968 GP P +G TG PP G+ G G P PG KGD+ P Sbjct: 632 TGPPGPQGLQGLPGTGGPP-----GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPP 686 Query: 969 PMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPD-DFHPDKRFGH 1027 ++ + G GPE GG+ GPP GP P P P +R Sbjct: 687 GLAGAPGLRGGAGPPGPE-----GGKGAAGPP---GP----PGAAGTPGLQGMPGER--- 731 Query: 1028 RLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGA----WEGRRPG 1083 G G P P+ +K GGPG P G+ RGP G +PG Sbjct: 732 -----GGLGSPGPKGDKGEPGGPGADGVP---------GKDGPRGPTGPIGPPGPAGQPG 777 Query: 1084 DERFPRDPEDPRFRGRREESFRRG--APPRHEGRAPPRGRDGFPGP--EDFGPEENFDAS 1139 D+ P P G R RG PP G G++G PG E P E + Sbjct: 778 DKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837 Query: 1140 EEAARGRDLRGRGRGTPRG--GRKGLLPTPDE-----FPRFEGGRKPDSWDGNR-EPGPG 1191 G G G P G G KG +P FP G P +GN PGP Sbjct: 838 PPGVAGPP-GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS 896 Query: 1192 HEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPG 1251 +P D PP PA + G+ + PG P Sbjct: 897 -----GSPGKDGPP----GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947 Query: 1252 GPSEDRGGKG----------RGGPGPAQRVPKSGR--SSSLDGEHHDGYHRDEPFGGPPG 1299 G + G +G RG PGP +SG+ ++ L GE GPPG Sbjct: 948 GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGER-----------GPPG 996 Query: 1300 -SGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGG 1332 G P G +G G+ + G P R S GG Sbjct: 997 PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGG 1030 Score = 201 bits (511), Expect = 4e-51 Identities = 191/575 (33%), Positives = 222/575 (38%), Gaps = 115/575 (20%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 PP ++GTP G Q PG+ G P P G PG G PG G Sbjct: 715 PPGAAGTP--GLQGMPGERG------GLGSPGPK-------GDKGEPGGPGADGVPGKDG 759 Query: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPP 693 GP GP G GP G G +G G P GLP + GP+G G GP GP G P Sbjct: 760 PRGPTGP---IGPPGPAGQPGDKGEGGAP-GLP---GIAGPRGSPGERGETGPPGPAGFP 812 Query: 694 GPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGM---QGPPGPRGMQ 750 G G +G G G +G PG +G GP G GP G GP GPPG QG+ +G PG G Sbjct: 813 GAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAA 872 Query: 751 GPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEM 810 G P G+ G PGS G GP GP G GPPGP N G AP + P + Sbjct: 873 GFPGARGLPGPPGSNGNPGP--PGP---SGSPGKDGPPGPAGNTG-APGSPGVSGPKGDA 926 Query: 811 RGPHPPGGLLGHGPQEMRGPQEI------RGMQGPPPQGSMLGPPQELRGPPGSQSQQGP 864 P G GP GP I RG+ GPP M GP RG PG Q +G Sbjct: 927 GQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPP---GMPGP----RGSPGPQGVKG- 978 Query: 865 PQGSLGPPPQGGMQGPPGPQG-------QQNPARGPHPSQGPIPFQQQKTPLLGD----- 912 G G G +GPPGPQG P R +P +P + GD Sbjct: 979 ESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG 1038 Query: 913 GPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSE 972 P AP G GPP + G+ G +G P P PGP SRG P GP Sbjct: 1039 SPGAP-GAPGH-PGPPGPVGPAGKSGDRGESGPAGPAGAPGP--AGSRGAP----GPQGP 1090 Query: 973 RRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREF 1032 R + G RG +G H FP + P Sbjct: 1091 RGDKGETGE---------RGAAGIKG-------HRGFPGNPGAP---------------- 1118 Query: 1033 EGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPE 1092 G P P ++ G PGP P G GPPG + G P Sbjct: 1119 ---GSPGPAGQQGAIGSPGPAGP---------RGPVGPSGPPG-----KDGTSGHPGPIG 1161 Query: 1093 DPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGP 1127 P RG R E G+ P H G+ P G G PGP Sbjct: 1162 PPGPRGNRGERGSEGS-PGHPGQPGPPGPPGAPGP 1195 Score = 191 bits (485), Expect = 4e-48 Identities = 158/463 (34%), Positives = 198/463 (42%), Gaps = 63/463 (13%) Query: 572 IQPPPSSGTP-------------LLGPQPFPGQ----GPMSQIPQGFQQPHPSQQMPMNM 614 I PP +G P + GP+ PG+ GP P GF P Sbjct: 767 IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPG--PAGFPGAPGQNGEPGGK 824 Query: 615 AQMGPPGPQGQFRPPG---PQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQ 669 + G PG +G+ PPG P G GP GPP GPQG G +G G P G P + Sbjct: 825 GERGAPGEKGEGGPPGVAGPPGGSGPAGPP------GPQGVKGERGSPGGPGAAGFPGAR 878 Query: 670 DMHGPQGMQRHPGPHGPLGP---QGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQ 726 + GP G +PGP GP G GPPGP G++G G G GP G G G +G PG Q Sbjct: 879 GLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQ 938 Query: 727 GHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQG 786 G P G PG G+ G G RG+ GPP G +G PG QG++G + GL+ G +G Sbjct: 939 G---PPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLS--GERG 993 Query: 787 PPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH-GPQEMRGPQEIRGMQGPPPQGSM 845 PPGP+ G A G P ++ G GL G G +G + G G P Sbjct: 994 PPGPQGLPGLAGTA---GEPGRD--GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048 Query: 846 LGPPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQ 903 GPP + GP G +G P G G P G +G PGPQG + +G +G + Sbjct: 1049 PGPPGPV-GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD-KGETGERGAAGIK 1106 Query: 904 QQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPP 963 + P AP S GP GQQGA G P P GP+ + Sbjct: 1107 GHRG--FPGNPGAP-----GSPGP------AGQQGAIGSPGPAGPRGPVGPSGPPGKDGT 1153 Query: 964 NHHMGPMSERRHEQSGGPEHGPERGPFRGGQ-DCRGPPDRRGP 1005 + H GP+ + G E G E P GQ GPP GP Sbjct: 1154 SGHPGPIGPPGPRGNRG-ERGSEGSPGHPGQPGPPGPPGAPGP 1195 Score = 139 bits (350), Expect = 2e-32 Identities = 194/661 (29%), Positives = 221/661 (33%), Gaps = 140/661 (21%) Query: 681 PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGM 740 P P P G PQ + P QGP GP+G GP G PG G G G PG+ G Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134 Query: 741 QGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQG 800 GPPG P P S ++ V+ G L G G GPPGP P P G Sbjct: 135 PGPPGICE-SCPTGPQNYSPQYDSYDVKSGVAVGGLAGYP--GPAGPPGP-----PGPPG 186 Query: 801 MIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQS 860 GHP P PG +G G P Q GPP GPPG+ Sbjct: 187 T-SGHPGS----PGSPG---------------YQGPPGEPGQAGPSGPP----GPPGAIG 222 Query: 861 QQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPF 918 GP G G P + G +G PGP G + PA P F K DG Sbjct: 223 PSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPG-------FPGMKGHRGFDGR---- 271 Query: 919 NQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQS 978 N E TG P L G G G P+ P PG RG P G R ++ + Sbjct: 272 NGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG-----ERGRPGLP-GAAGARGNDGA 325 Query: 979 GGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGP 1038 G + P GP GPP G FP + P G + RG P Sbjct: 326 RGSDGQP--GP-------PGPPGTAG----FPGSPGAKGEVGPAGSPGSNGAPGQ-RGEP 371 Query: 1039 LPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRG 1098 PQ G GPP PP G G G PGA P RG Sbjct: 372 GPQGHA---GAQGPPGPPGINGSPGGKGEMGPAGIPGA--------------PGLMGARG 414 Query: 1099 RREESFRRGAPPRHEGRAPP--RGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTP 1156 + GAP G P G G PGP E A+G D + G P Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVP-GAKGEDGKDGSPGEP 473 Query: 1157 RGGRKGLLPTPDE--FPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASR 1214 G GL E P F G P+ G E GP E R P P P P Sbjct: 474 --GANGLPGAAGERGAPGFRGPAGPNGIPG--EKGPAGE--RGAPGPAGPRGAAGEPG-- 525 Query: 1215 ERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKS 1274 R G M +P +PGGP D G PGP +S Sbjct: 526 -RDGVPGGPGMRGMPG------------------SPGGPGSD------GKPGPPGSQGES 560 Query: 1275 GRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGR 1334 GR GPPG P G+ G G N G P + RGG Sbjct: 561 GRP------------------GPPGPSGPR--GQPGVMGFPGPKGNDGAPGKNGERGGPG 600 Query: 1335 G 1335 G Sbjct: 601 G 601 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 237 bits (605), Expect = 5e-62 Identities = 253/801 (31%), Positives = 312/801 (38%), Gaps = 127/801 (15%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 G PGP G+ G G++GP+G P G GP+G +GP+GP G P G P + M GPQG Sbjct: 494 GLPGPPGEDGERGDDGEIGPRGLP---GESGPRGLLGPKGPPGIP-GPPGVRGMDGPQGP 549 Query: 678 QRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGT 737 + G GP G GPPG QG+ G QG GPQG GP G GPQG PG G G GPPG Sbjct: 550 K---GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606 Query: 738 QGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-------------------PVSQGPLMG 778 G +GPPG +G QGP P G G PG +G++G P +G + Sbjct: 607 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 666 Query: 779 LNPRGMQGPPGPRENQGP-APQGMI--MGHP-PQEMRGPHPPGGLLG-HGPQEMRGPQEI 833 RG G PG R GP P+G G P P + G G+ G G +GP+ Sbjct: 667 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 726 Query: 834 RGMQGPPPQGSMLGP--------PQELRGPPGSQSQQGP-----PQGSLGPPPQGGMQGP 880 G G P G P+ RGP G + Q+GP G+ G G GP Sbjct: 727 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP 786 Query: 881 PGPQGQQNPARGPHPSQGP--IPFQQQKTPLLG-DGPRAPFNQEGQSTGPPPLIPGLGQQ 937 PG +G P +GP+ GP P K L G G R +G+ TGPP +G Q Sbjct: 787 PGERGLPGP-QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK-TGPPGPPGVVGPQ 844 Query: 938 GAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGG-QDC 996 GA G P+ PGP GPP P + + G P GP P + G Sbjct: 845 GAAGETGPMGERGHPGP-----PGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDGPAGL 897 Query: 997 RGPPDRRGPHPDFPDDFSRP-------DDFHPDKRFGHRLREFEGRGGPL---------- 1039 RG P RG P P P R G GGP+ Sbjct: 898 RGFPGERG----LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 953 Query: 1040 PQEEKWRRGGPGP--PFPPDHREFSEGD-GRGAARGPPGAWEGRRPGDERFPRDPEDPRF 1096 P +G PG P P R+ +G G GPPG GD+ DP Sbjct: 954 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV--AGEDGDKGEVGDPGQKGT 1011 Query: 1097 RGRREESFRRGAPPRHEGRAPPRGRDGFPG----PEDFGPEENFDA-SEEAARG------ 1145 +G + E PP G P G+ G G P GP+ +F A +E RG Sbjct: 1012 KGNKGEH----GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1067 Query: 1146 ----RDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRP 1201 + L G G G + P P G P+ DG + P PG P Sbjct: 1068 PIGLQGLPGPSGEKGETGDVGPMGPPGP-PGPRGPAGPNGADGPQGP-PGGVGNLGPPGE 1125 Query: 1202 DHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKG 1261 P + SP +QG P +R G P GP+ D G KG Sbjct: 1126 KGEPGESGSP-------GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1178 Query: 1262 R-------GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWG 1314 G PGP P G DG D EP G PGS P+ G +G Sbjct: 1179 NPGPVGFPGDPGP----PGEGGPRGQDGAKGDRGEDGEP--GQPGSPGPT--GENGPPGP 1230 Query: 1315 RGSNMNSGPPRRGASRGGGRG 1335 G +G P R GG+G Sbjct: 1231 LGKRGPAGSP-GSEGRQGGKG 1250 Score = 231 bits (588), Expect = 5e-60 Identities = 263/849 (30%), Positives = 327/849 (38%), Gaps = 161/849 (18%) Query: 583 LGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQG--- 639 +GP+ PG+ P+G P +P GPPG +G P GP+G +GPQG Sbjct: 511 IGPRGLPGESG----PRGLLGPKGPPGIP------GPPGVRGMDGPQGPKGSLGPQGEPG 560 Query: 640 PPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSS 699 PP QG G QG GPQG GP G PQ G GM GP G G +GPPG +G+ Sbjct: 561 PPGQQGTPGTQGLPGPQGAIGP-HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 619 Query: 700 GPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP---------------------PGTQ 738 GP G GP G PGP+G G G G +GH G +G PG++ Sbjct: 620 GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR 679 Query: 739 GMQGPPGPRGMQGP---PHPHGIQGGPGSQGIQG----PVSQGPLMGLN----------- 780 G GP GP+G GP P P G+ G G G+ G P QGP L Sbjct: 680 GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 739 Query: 781 ----------PRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMR 828 PRG +GP GPR +GP G GPH P G G GPQ Sbjct: 740 GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 799 Query: 829 GPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQ 886 G +G GPP + + G P + RG G Q + GPP G +GP G GP G +G Sbjct: 800 GFPGPKGPPGPPGKDGLPGHPGQ-RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858 Query: 887 QNPARGPHPSQGPIPFQQQKTPLLGDG--PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIP 944 P GP QG +P K GD P AP GP L G++G +P Sbjct: 859 PGPP-GPPGEQG-LPGTAGKEGTKGDPGPPGAPGKD-----GPAGLRGFPGERG----LP 907 Query: 945 PLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP-----EHGPERGPFRGGQDCRGP 999 G G N+G S GPP P ER SGGP GP+ P G+ +G Sbjct: 908 GTAGGPGLKGNEGPS-GPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGE--KGV 963 Query: 1000 PDRRGPHPDFPDD-----FSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPF 1054 P +GP D P P G + E G P + K +G GPP Sbjct: 964 PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV-GDPGQKGTKGNKGEHGPPG 1022 Query: 1055 PPD------HREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDP-RFRGRREESFRRG 1107 PP + DG ARGP G + + R P P +G S +G Sbjct: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1082 Query: 1108 -----------APPRHEGRAPPRGRDGFPGPE----DFGPE-ENFDASEEAARGRDLRGR 1151 PP G A P G DG GP + GP E + E + G ++G Sbjct: 1083 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG--IQGE 1140 Query: 1152 -GRGTPRG--GRKGLLPTPDEFPRFEGGRKPDSWDGNR-EPGPGHEHFRDTPRPDHPPHD 1207 G PRG G KG P E P G + P DG + PGP P PP + Sbjct: 1141 PGVKGPRGERGEKGESGQPGE-PGPPGPKGPTGDDGPKGNPGPV-----GFPGDPGPPGE 1194 Query: 1208 GHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGP-G 1266 G P ++ + +G D E PG P G G GP G Sbjct: 1195 G-GPRGQDGAKGDRGED--------------------GEPGQPGSP----GPTGENGPPG 1229 Query: 1267 PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS----GTPSRGGRSGSNWGRGSNMNSG 1322 P + +G S + G D G PG G G+ G + RG + G Sbjct: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289 Query: 1323 PPRRGASRG 1331 R + G Sbjct: 1290 QQGRPGATG 1298 Score = 229 bits (583), Expect = 2e-59 Identities = 235/775 (30%), Positives = 294/775 (37%), Gaps = 162/775 (20%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQ 675 G GP+G+ P GP+GQ GP+G G G +G G GP GPP +GLP PQ +G Sbjct: 746 GKSGPRGERGPTGPRGQRGPRGAT---GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802 Query: 676 GMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPG---PQGHIGPQGPPGPQGHLGPQ 732 G + PGP G G G PG +G G QG GP GPPG PQG G GP G +GH GP Sbjct: 803 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862 Query: 733 GPPGTQGM---------QGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN-PR 782 GPPG QG+ +G PGP G G P G++G PG +G+ G L G P Sbjct: 863 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 922 Query: 783 GMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH----GPQEMRGPQEIRGMQG 838 G GP G +G A G +G P + GP P G G G + GP G+QG Sbjct: 923 GPPGPAGSPGERGAAGSGGPIGPPGRP--GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG 980 Query: 839 PPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNP--------- 889 P GPP + G G + + G P G G G GPPGP G P Sbjct: 981 PVGLPGPAGPPG-VAGEDGDKGEVGDP-GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1038 Query: 890 -----ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG-LGQQGAQGRI 943 ARGP QG + + +GP P +G +PG G++G G + Sbjct: 1039 DGEPGARGP---QGHFGAKGDEGTRGFNGPPGPIGLQG--------LPGPSGEKGETGDV 1087 Query: 944 PPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRR 1003 P+ P PGP RGP GP + GP+ P GG GPP + Sbjct: 1088 GPMGPPGPPGP-----RGPA----GPNG------ADGPQGPP------GGVGNLGPPGEK 1126 Query: 1004 GPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQE-EKWRRGGPGPPFPPDHREFS 1062 G P + P ++ G GP + EK G PG P PP + + Sbjct: 1127 GE----PGESGSPG-----------IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171 Query: 1063 EGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRG-----APPRHEGRAP 1117 DG GP G FP DP P G R + +G P G Sbjct: 1172 GDDGPKGNPGPVG-----------FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1220 Query: 1118 PRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGR 1177 P G +G PGP SE G+ +G G+ G P P + G Sbjct: 1221 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG--PVGPAGPAGKPG- 1277 Query: 1178 KPDSWDG-----NREPGPGHEHFRDTPRPDHPP-------------HDGH-------SPA 1212 PD G ++ PG P P PP GH P Sbjct: 1278 -PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP 1336 Query: 1213 SRERSSSLQGMDMASLPPRKR-----PWHDGP-GTSEHREMEAPGGPSEDRGGKGRGG-- 1264 + +G+ P ++ P GP G + P GP +G G GG Sbjct: 1337 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1396 Query: 1265 -----------PGPAQRV--------PKSGRSSSLDGEHHDGYHRDEPFGGPPGS 1300 PGP V PK R S+DG P GG PGS Sbjct: 1397 GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTR-RSVDGSRLMQEDEAIPTGGAPGS 1450 Score = 220 bits (560), Expect = 8e-57 Identities = 204/638 (31%), Positives = 246/638 (38%), Gaps = 115/638 (18%) Query: 574 PPPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632 PP G P GP FPG P+G P +P + Q G G QG+ PPGP Sbjct: 786 PPGERGLPGPQGPNGFPG-------PKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 838 Query: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQ 690 G +GPQG G GP G G GP GPP QGLP G +G + PGP G G Sbjct: 839 GVVGPQGAA---GETGPMGERGHPGPPGPPGEQGLPGTA---GKEGTKGDPGPPGAPGKD 892 Query: 691 GPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQ 750 GP G +G G +G G G PG +G+ GP GPPGP G G +G G+ G GPPG G Q Sbjct: 893 GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 952 Query: 751 GPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQE- 809 GPP G +G PG +G GP + + G P G+ GP GP G +G P Q+ Sbjct: 953 GPPGAAGEKGVPGEKGPIGPTGRDGVQG--PVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1010 Query: 810 ------MRGPHPPGGLLG----------------HGPQE---MRGPQEIRGMQGPP---- 840 GP P G +G GPQ +G + RG GPP Sbjct: 1011 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1070 Query: 841 ------PQGSM--------LGPP-----QELRGPPGSQSQQGPPQG--SLGPPPQGGMQG 879 P G +GPP + GP G+ QGPP G +LGPP + G G Sbjct: 1071 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130 Query: 880 PPGPQGQQNP--ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPL-IPG--- 933 G G Q +GP +G Q GP+ P +G P P+ PG Sbjct: 1131 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1190 Query: 934 -------LGQQGAQG-RIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGP 985 GQ GA+G R PGQ P GPP GP+ +R S G E Sbjct: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP----GPLGKRGPAGSPGSEGRQ 1246 Query: 986 ERGPFRGGQDCRGPPDRRGP-HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEK 1044 +G G P + GP P P PD LR G G + Sbjct: 1247 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG----------LRGLPGSVGQQGRPGA 1296 Query: 1045 WRRGGPGPPFPPDHREFSEGDGRGAAR----------GPPGAWEGRRPGDERFPRDPEDP 1094 + GP P P GD GPPG E GD P P Sbjct: 1297 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG--EQGEKGDRGLPGPQGSP 1354 Query: 1095 RFRGRR-----EESFRRGAPPRHEGRAPPRGRDGFPGP 1127 +G G PP G A P+G G GP Sbjct: 1355 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGP 1392 Score = 218 bits (555), Expect = 3e-56 Identities = 261/896 (29%), Positives = 335/896 (37%), Gaps = 159/896 (17%) Query: 538 QAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPP----PSSGTPLLGPQP------ 587 Q E+E E Q PQ + + +R Q+Q ++ P P S P G + Sbjct: 223 QKELECEGG--QRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESS 280 Query: 588 -FPGQGPMSQIPQGF--QQPHPSQQMPMNMAQMGPPGPQGQ---FRPPGPQGQMGPQGPP 641 P + P+G ++ P+ P M GPPGP+G PPG QG GP G P Sbjct: 281 LLPPLEEAAHGPRGLKGEKGEPAVLEP-GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDP 339 Query: 642 LHQGGGGPQGFMGPQGPQGPP-QGLPRP-----------------------------QDM 671 +G G G G G GPP L P + Sbjct: 340 GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLAL 399 Query: 672 HGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHL-- 729 GP G + G GPLG G PG +G S G +GPQGP GPQG GP G G +G Sbjct: 400 RGPPGPMGYTGRPGPLGQPGSPGLKGES---GDLGPQGPRGPQGLTGPPGKAGRRGRAGA 456 Query: 730 -GPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMG----LNPRGM 784 G +G PG G++G G G+ G P G +G G+QG+ GP + G + PRG+ Sbjct: 457 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 516 Query: 785 QGPPGPRENQGPAPQGMIMGHP-PQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQG----P 839 G GPR GP I G P + M GP P G L GPQ GP +G G P Sbjct: 517 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL--GPQGEPGPPGQQGTPGTQGLP 574 Query: 840 PPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP 899 PQG+ +GP E +GP G G P GS GPP G +GPPG +G Q P+ GP QGP Sbjct: 575 GPQGA-IGPHGE-KGPQGKPGLPGMP-GSDGPPGHPGKEGPPGTKGNQGPS-GP---QGP 627 Query: 900 IPFQQQKTPLLGDGPRAPFNQEGQ--STGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKG 957 + + + DG R +G+ G P +G +G +G + PG Sbjct: 628 LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV------PGSRGE 681 Query: 958 DSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGP-----HPDFPDD 1012 D P GP + G P E+G G G P R+GP P FP Sbjct: 682 DGPEGPKGRTGPTGD-----PGPPGLMGEKGKL-GVPGLPGYPGRQGPKGSLGFPGFPGA 735 Query: 1013 FSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARG 1072 R G+ GP RG GP P R G+ A+G Sbjct: 736 SGEKG-----------ARGLSGKSGP--------RGERGPTGPRGQRGPRGATGKSGAKG 776 Query: 1073 PPGAWEGRRPGDERFPRDPEDPRF----RGRREESFRRGAP--PRHEGRAPPRGRDGFPG 1126 G P ER P+ P +G + G P P G +G+ G PG Sbjct: 777 TSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 836 Query: 1127 PED-FGPEENFDASEEAARGRDLRGRGRGTPRG--GRKGLL-----------PTPDEFPR 1172 P GP+ A E G RG P G G +GL P P P Sbjct: 837 PPGVVGPQG--AAGETGPMGE----RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890 Query: 1173 FEGGRKPDSWDGNRE-PG-PGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPP 1230 +G + G R PG G + P PP SP R + S + P Sbjct: 891 KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS-----GGPIGP 945 Query: 1231 RKRPWHDG-PGTSEHREMEAPGGPSEDRGGKGRGGP-------GPAQRVPKSGRSSSLDG 1282 RP G PG + + + GP G G GP GP + G + Sbjct: 946 PGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGD 1005 Query: 1283 EHHDGYHRDEPFGGPPGS-------GTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 G ++ GPPG G P G G RG + G +RG Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1061 Score = 191 bits (484), Expect = 5e-48 Identities = 142/385 (36%), Positives = 169/385 (43%), Gaps = 54/385 (14%) Query: 599 QGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP 658 QG P + ++ MGPPGP G P GP G GPQGPP G GP G G G Sbjct: 1072 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1131 Query: 659 QGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGH 716 G P QG P + G +G + G G GP GP GP G GP+G+ GP G PG G Sbjct: 1132 SGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1191 Query: 717 IGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHP---HGIQGGPGSQGIQGPVSQ 773 G GP G G G +G G G G PGP G GPP P G G PGS+G QG Sbjct: 1192 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG---- 1247 Query: 774 GPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH-GPQEMRGPQE 832 +G +G PG +G P + GP P G G GP +RG Sbjct: 1248 -------GKGAKGDPG------------AIGAPGK--TGPVGPAGPAGKPGPDGLRGLPG 1286 Query: 833 IRGMQGPPPQGSMLGPPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQNPA 890 G QG P GPP + GPPG +G +G G P G+ GPPG QG++ Sbjct: 1287 SVGQQGRPGATGQAGPPGPV-GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1345 Query: 891 RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG-LGQQGAQGRIPPLNPG 949 P P P + P GP P G PP +PG G +GA+G Sbjct: 1346 GLPGPQGSPGQKGEMGIP-GASGPIGP--------GGPPGLPGPAGPKGAKG-------A 1389 Query: 950 QGPGPNKGDS--RGPPNHHMGPMSE 972 GPG KG+ +GPP H GP E Sbjct: 1390 TGPGGPKGEKGVQGPPG-HPGPPGE 1413 Score = 148 bits (373), Expect = 4e-35 Identities = 122/354 (34%), Positives = 143/354 (40%), Gaps = 86/354 (24%) Query: 584 GPQPFPGQ-GPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPP 641 GP FPG GP + P+G + Q G PGP G+ PPGP G+ GP G P Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240 Query: 642 LHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGP 701 G +G G +G +G P G G GP GP GP G PGP G G Sbjct: 1241 ------GSEGRQGGKGAKGDP----------GAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1284 Query: 702 QGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGG 761 G +G QG PG G GP GP GP G G +G G +G +G PG G+ GPP G QG Sbjct: 1285 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP---GEQGE 1341 Query: 762 PGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG-PAPQGMIMGHPPQEMRGPHPPGGLL 820 G +G+ GP QG PG + G P G I GP P GL Sbjct: 1342 KGDRGLPGP--------------QGSPGQKGEMGIPGASGPI---------GPGGPPGLP 1378 Query: 821 GHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGP 880 G GP+ +G GP GP G + QGPP G GP Sbjct: 1379 GPA-----GPKGAKGATGP-------------GGPKGEKGVQGPP----------GHPGP 1410 Query: 881 PGPQGQQNPARGPHPSQGPIPFQQ-QKTPLLGDGPRAPFNQEGQSTGPPPLIPG 933 PG Q P+P Q +KT DG R E TG P PG Sbjct: 1411 PGEVIQ------------PLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 237 bits (605), Expect = 5e-62 Identities = 253/801 (31%), Positives = 312/801 (38%), Gaps = 127/801 (15%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 G PGP G+ G G++GP+G P G GP+G +GP+GP G P G P + M GPQG Sbjct: 473 GLPGPPGEDGERGDDGEIGPRGLP---GESGPRGLLGPKGPPGIP-GPPGVRGMDGPQGP 528 Query: 678 QRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGT 737 + G GP G GPPG QG+ G QG GPQG GP G GPQG PG G G GPPG Sbjct: 529 K---GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 585 Query: 738 QGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-------------------PVSQGPLMG 778 G +GPPG +G QGP P G G PG +G++G P +G + Sbjct: 586 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 645 Query: 779 LNPRGMQGPPGPRENQGP-APQGMI--MGHP-PQEMRGPHPPGGLLG-HGPQEMRGPQEI 833 RG G PG R GP P+G G P P + G G+ G G +GP+ Sbjct: 646 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 705 Query: 834 RGMQGPPPQGSMLGP--------PQELRGPPGSQSQQGP-----PQGSLGPPPQGGMQGP 880 G G P G P+ RGP G + Q+GP G+ G G GP Sbjct: 706 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP 765 Query: 881 PGPQGQQNPARGPHPSQGP--IPFQQQKTPLLG-DGPRAPFNQEGQSTGPPPLIPGLGQQ 937 PG +G P +GP+ GP P K L G G R +G+ TGPP +G Q Sbjct: 766 PGERGLPGP-QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK-TGPPGPPGVVGPQ 823 Query: 938 GAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGG-QDC 996 GA G P+ PGP GPP P + + G P GP P + G Sbjct: 824 GAAGETGPMGERGHPGP-----PGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDGPAGL 876 Query: 997 RGPPDRRGPHPDFPDDFSRP-------DDFHPDKRFGHRLREFEGRGGPL---------- 1039 RG P RG P P P R G GGP+ Sbjct: 877 RGFPGERG----LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 932 Query: 1040 PQEEKWRRGGPGP--PFPPDHREFSEGD-GRGAARGPPGAWEGRRPGDERFPRDPEDPRF 1096 P +G PG P P R+ +G G GPPG GD+ DP Sbjct: 933 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV--AGEDGDKGEVGDPGQKGT 990 Query: 1097 RGRREESFRRGAPPRHEGRAPPRGRDGFPG----PEDFGPEENFDA-SEEAARG------ 1145 +G + E PP G P G+ G G P GP+ +F A +E RG Sbjct: 991 KGNKGEH----GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1046 Query: 1146 ----RDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRP 1201 + L G G G + P P G P+ DG + P PG P Sbjct: 1047 PIGLQGLPGPSGEKGETGDVGPMGPPGP-PGPRGPAGPNGADGPQGP-PGGVGNLGPPGE 1104 Query: 1202 DHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKG 1261 P + SP +QG P +R G P GP+ D G KG Sbjct: 1105 KGEPGESGSP-------GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1157 Query: 1262 R-------GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWG 1314 G PGP P G DG D EP G PGS P+ G +G Sbjct: 1158 NPGPVGFPGDPGP----PGEGGPRGQDGAKGDRGEDGEP--GQPGSPGPT--GENGPPGP 1209 Query: 1315 RGSNMNSGPPRRGASRGGGRG 1335 G +G P R GG+G Sbjct: 1210 LGKRGPAGSP-GSEGRQGGKG 1229 Score = 231 bits (588), Expect = 5e-60 Identities = 263/849 (30%), Positives = 327/849 (38%), Gaps = 161/849 (18%) Query: 583 LGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQG--- 639 +GP+ PG+ P+G P +P GPPG +G P GP+G +GPQG Sbjct: 490 IGPRGLPGESG----PRGLLGPKGPPGIP------GPPGVRGMDGPQGPKGSLGPQGEPG 539 Query: 640 PPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSS 699 PP QG G QG GPQG GP G PQ G GM GP G G +GPPG +G+ Sbjct: 540 PPGQQGTPGTQGLPGPQGAIGP-HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 598 Query: 700 GPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP---------------------PGTQ 738 GP G GP G PGP+G G G G +GH G +G PG++ Sbjct: 599 GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR 658 Query: 739 GMQGPPGPRGMQGP---PHPHGIQGGPGSQGIQG----PVSQGPLMGLN----------- 780 G GP GP+G GP P P G+ G G G+ G P QGP L Sbjct: 659 GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 718 Query: 781 ----------PRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMR 828 PRG +GP GPR +GP G GPH P G G GPQ Sbjct: 719 GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 778 Query: 829 GPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQ 886 G +G GPP + + G P + RG G Q + GPP G +GP G GP G +G Sbjct: 779 GFPGPKGPPGPPGKDGLPGHPGQ-RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837 Query: 887 QNPARGPHPSQGPIPFQQQKTPLLGDG--PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIP 944 P GP QG +P K GD P AP GP L G++G +P Sbjct: 838 PGPP-GPPGEQG-LPGTAGKEGTKGDPGPPGAPGKD-----GPAGLRGFPGERG----LP 886 Query: 945 PLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP-----EHGPERGPFRGGQDCRGP 999 G G N+G S GPP P ER SGGP GP+ P G+ +G Sbjct: 887 GTAGGPGLKGNEGPS-GPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGE--KGV 942 Query: 1000 PDRRGPHPDFPDD-----FSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPF 1054 P +GP D P P G + E G P + K +G GPP Sbjct: 943 PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV-GDPGQKGTKGNKGEHGPPG 1001 Query: 1055 PPD------HREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDP-RFRGRREESFRRG 1107 PP + DG ARGP G + + R P P +G S +G Sbjct: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1061 Query: 1108 -----------APPRHEGRAPPRGRDGFPGPE----DFGPE-ENFDASEEAARGRDLRGR 1151 PP G A P G DG GP + GP E + E + G ++G Sbjct: 1062 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG--IQGE 1119 Query: 1152 -GRGTPRG--GRKGLLPTPDEFPRFEGGRKPDSWDGNR-EPGPGHEHFRDTPRPDHPPHD 1207 G PRG G KG P E P G + P DG + PGP P PP + Sbjct: 1120 PGVKGPRGERGEKGESGQPGE-PGPPGPKGPTGDDGPKGNPGPV-----GFPGDPGPPGE 1173 Query: 1208 GHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGP-G 1266 G P ++ + +G D E PG P G G GP G Sbjct: 1174 G-GPRGQDGAKGDRGED--------------------GEPGQPGSP----GPTGENGPPG 1208 Query: 1267 PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS----GTPSRGGRSGSNWGRGSNMNSG 1322 P + +G S + G D G PG G G+ G + RG + G Sbjct: 1209 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1268 Query: 1323 PPRRGASRG 1331 R + G Sbjct: 1269 QQGRPGATG 1277 Score = 229 bits (583), Expect = 2e-59 Identities = 235/775 (30%), Positives = 294/775 (37%), Gaps = 162/775 (20%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQ 675 G GP+G+ P GP+GQ GP+G G G +G G GP GPP +GLP PQ +G Sbjct: 725 GKSGPRGERGPTGPRGQRGPRGAT---GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781 Query: 676 GMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPG---PQGHIGPQGPPGPQGHLGPQ 732 G + PGP G G G PG +G G QG GP GPPG PQG G GP G +GH GP Sbjct: 782 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841 Query: 733 GPPGTQGM---------QGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN-PR 782 GPPG QG+ +G PGP G G P G++G PG +G+ G L G P Sbjct: 842 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 901 Query: 783 GMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH----GPQEMRGPQEIRGMQG 838 G GP G +G A G +G P + GP P G G G + GP G+QG Sbjct: 902 GPPGPAGSPGERGAAGSGGPIGPPGRP--GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG 959 Query: 839 PPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNP--------- 889 P GPP + G G + + G P G G G GPPGP G P Sbjct: 960 PVGLPGPAGPPG-VAGEDGDKGEVGDP-GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1017 Query: 890 -----ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG-LGQQGAQGRI 943 ARGP QG + + +GP P +G +PG G++G G + Sbjct: 1018 DGEPGARGP---QGHFGAKGDEGTRGFNGPPGPIGLQG--------LPGPSGEKGETGDV 1066 Query: 944 PPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRR 1003 P+ P PGP RGP GP + GP+ P GG GPP + Sbjct: 1067 GPMGPPGPPGP-----RGPA----GPNG------ADGPQGPP------GGVGNLGPPGEK 1105 Query: 1004 GPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQE-EKWRRGGPGPPFPPDHREFS 1062 G P + P ++ G GP + EK G PG P PP + + Sbjct: 1106 GE----PGESGSPG-----------IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150 Query: 1063 EGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRG-----APPRHEGRAP 1117 DG GP G FP DP P G R + +G P G Sbjct: 1151 GDDGPKGNPGPVG-----------FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1199 Query: 1118 PRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGR 1177 P G +G PGP SE G+ +G G+ G P P + G Sbjct: 1200 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG--PVGPAGPAGKPG- 1256 Query: 1178 KPDSWDG-----NREPGPGHEHFRDTPRPDHPP-------------HDGH-------SPA 1212 PD G ++ PG P P PP GH P Sbjct: 1257 -PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP 1315 Query: 1213 SRERSSSLQGMDMASLPPRKR-----PWHDGP-GTSEHREMEAPGGPSEDRGGKGRGG-- 1264 + +G+ P ++ P GP G + P GP +G G GG Sbjct: 1316 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1375 Query: 1265 -----------PGPAQRV--------PKSGRSSSLDGEHHDGYHRDEPFGGPPGS 1300 PGP V PK R S+DG P GG PGS Sbjct: 1376 GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTR-RSVDGSRLMQEDEAIPTGGAPGS 1429 Score = 220 bits (560), Expect = 8e-57 Identities = 204/638 (31%), Positives = 246/638 (38%), Gaps = 115/638 (18%) Query: 574 PPPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632 PP G P GP FPG P+G P +P + Q G G QG+ PPGP Sbjct: 765 PPGERGLPGPQGPNGFPG-------PKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 817 Query: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQ 690 G +GPQG G GP G G GP GPP QGLP G +G + PGP G G Sbjct: 818 GVVGPQGAA---GETGPMGERGHPGPPGPPGEQGLPGTA---GKEGTKGDPGPPGAPGKD 871 Query: 691 GPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQ 750 GP G +G G +G G G PG +G+ GP GPPGP G G +G G+ G GPPG G Q Sbjct: 872 GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 931 Query: 751 GPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQE- 809 GPP G +G PG +G GP + + G P G+ GP GP G +G P Q+ Sbjct: 932 GPPGAAGEKGVPGEKGPIGPTGRDGVQG--PVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 989 Query: 810 ------MRGPHPPGGLLG----------------HGPQE---MRGPQEIRGMQGPP---- 840 GP P G +G GPQ +G + RG GPP Sbjct: 990 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1049 Query: 841 ------PQGSM--------LGPP-----QELRGPPGSQSQQGPPQG--SLGPPPQGGMQG 879 P G +GPP + GP G+ QGPP G +LGPP + G G Sbjct: 1050 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109 Query: 880 PPGPQGQQNP--ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPL-IPG--- 933 G G Q +GP +G Q GP+ P +G P P+ PG Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1169 Query: 934 -------LGQQGAQG-RIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGP 985 GQ GA+G R PGQ P GPP GP+ +R S G E Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP----GPLGKRGPAGSPGSEGRQ 1225 Query: 986 ERGPFRGGQDCRGPPDRRGP-HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEK 1044 +G G P + GP P P PD LR G G + Sbjct: 1226 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG----------LRGLPGSVGQQGRPGA 1275 Query: 1045 WRRGGPGPPFPPDHREFSEGDGRGAAR----------GPPGAWEGRRPGDERFPRDPEDP 1094 + GP P P GD GPPG E GD P P Sbjct: 1276 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG--EQGEKGDRGLPGPQGSP 1333 Query: 1095 RFRGRR-----EESFRRGAPPRHEGRAPPRGRDGFPGP 1127 +G G PP G A P+G G GP Sbjct: 1334 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGP 1371 Score = 218 bits (555), Expect = 3e-56 Identities = 259/883 (29%), Positives = 332/883 (37%), Gaps = 154/883 (17%) Query: 538 QAEIEQEMATLQYTNPQLLEQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQI 597 Q E+E E Q PQ + + +R Q+Q ++ P + PQ GP Sbjct: 223 QKELECEGG--QRERPQNQQPHRAQRSPQQQPSRLHRPQNQE-----PQSQAAHGPRGL- 274 Query: 598 PQGFQQPHPSQQMPMNMAQMGPPGPQGQ---FRPPGPQGQMGPQGPPLHQGGGGPQGFMG 654 +G ++ P+ P M GPPGP+G PPG QG GP G P +G G G G Sbjct: 275 -KG-EKGEPAVLEP-GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPG 331 Query: 655 PQGPQGPP-QGLPRP-----------------------------QDMHGPQGMQRHPGPH 684 G GPP L P + GP G + G Sbjct: 332 SDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRP 391 Query: 685 GPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHL---GPQGPPGTQGMQ 741 GPLG G PG +G S G +GPQGP GPQG GP G G +G G +G PG G++ Sbjct: 392 GPLGQPGSPGLKGES---GDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 448 Query: 742 GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMG----LNPRGMQGPPGPRENQGPA 797 G G G+ G P G +G G+QG+ GP + G + PRG+ G GPR GP Sbjct: 449 GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 508 Query: 798 PQGMIMGHP-PQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQG----PPPQGSMLGPPQEL 852 I G P + M GP P G L GPQ GP +G G P PQG+ +GP E Sbjct: 509 GPPGIPGPPGVRGMDGPQGPKGSL--GPQGEPGPPGQQGTPGTQGLPGPQGA-IGPHGE- 564 Query: 853 RGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD 912 +GP G G P GS GPP G +GPPG +G Q P+ GP QGP+ + + D Sbjct: 565 KGPQGKPGLPGMP-GSDGPPGHPGKEGPPGTKGNQGPS-GP---QGPLGYPGPRGVKGVD 619 Query: 913 GPRAPFNQEGQ--STGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPM 970 G R +G+ G P +G +G +G + PG D P GP Sbjct: 620 GIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGV------PGSRGEDGPEGPKGRTGPT 673 Query: 971 SERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGP-----HPDFPDDFSRPDDFHPDKRF 1025 + G P E+G G G P R+GP P FP Sbjct: 674 GD-----PGPPGLMGEKGKL-GVPGLPGYPGRQGPKGSLGFPGFPGASGEKG-------- 719 Query: 1026 GHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDE 1085 R G+ GP RG GP P R G+ A+G G P E Sbjct: 720 ---ARGLSGKSGP--------RGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 768 Query: 1086 RFPRDPEDPRF----RGRREESFRRGAP--PRHEGRAPPRGRDGFPGPED-FGPEENFDA 1138 R P+ P +G + G P P G +G+ G PGP GP+ A Sbjct: 769 RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG--AA 826 Query: 1139 SEEAARGRDLRGRGRGTPRG--GRKGLL-----------PTPDEFPRFEGGRKPDSWDGN 1185 E G RG P G G +GL P P P +G + G Sbjct: 827 GETGPMGE----RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGE 882 Query: 1186 RE-PG-PGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDG-PGTS 1242 R PG G + P PP SP R + S + P RP G PG + Sbjct: 883 RGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS-----GGPIGPPGRPGPQGPPGAA 937 Query: 1243 EHREMEAPGGPSEDRGGKGRGGP-------GPAQRVPKSGRSSSLDGEHHDGYHRDEPFG 1295 + + GP G G GP GP + G + G ++ Sbjct: 938 GEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEH 997 Query: 1296 GPPGS-------GTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 GPPG G P G G RG + G +RG Sbjct: 998 GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRG 1040 Score = 191 bits (484), Expect = 5e-48 Identities = 142/385 (36%), Positives = 169/385 (43%), Gaps = 54/385 (14%) Query: 599 QGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP 658 QG P + ++ MGPPGP G P GP G GPQGPP G GP G G G Sbjct: 1051 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1110 Query: 659 QGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGH 716 G P QG P + G +G + G G GP GP GP G GP+G+ GP G PG G Sbjct: 1111 SGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1170 Query: 717 IGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHP---HGIQGGPGSQGIQGPVSQ 773 G GP G G G +G G G G PGP G GPP P G G PGS+G QG Sbjct: 1171 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG---- 1226 Query: 774 GPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH-GPQEMRGPQE 832 +G +G PG +G P + GP P G G GP +RG Sbjct: 1227 -------GKGAKGDPG------------AIGAPGK--TGPVGPAGPAGKPGPDGLRGLPG 1265 Query: 833 IRGMQGPPPQGSMLGPPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQNPA 890 G QG P GPP + GPPG +G +G G P G+ GPPG QG++ Sbjct: 1266 SVGQQGRPGATGQAGPPGPV-GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1324 Query: 891 RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG-LGQQGAQGRIPPLNPG 949 P P P + P GP P G PP +PG G +GA+G Sbjct: 1325 GLPGPQGSPGQKGEMGIP-GASGPIGP--------GGPPGLPGPAGPKGAKG-------A 1368 Query: 950 QGPGPNKGDS--RGPPNHHMGPMSE 972 GPG KG+ +GPP H GP E Sbjct: 1369 TGPGGPKGEKGVQGPPG-HPGPPGE 1392 Score = 148 bits (373), Expect = 4e-35 Identities = 122/354 (34%), Positives = 143/354 (40%), Gaps = 86/354 (24%) Query: 584 GPQPFPGQ-GPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPP 641 GP FPG GP + P+G + Q G PGP G+ PPGP G+ GP G P Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219 Query: 642 LHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGP 701 G +G G +G +G P G G GP GP GP G PGP G G Sbjct: 1220 ------GSEGRQGGKGAKGDP----------GAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1263 Query: 702 QGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGG 761 G +G QG PG G GP GP GP G G +G G +G +G PG G+ GPP G QG Sbjct: 1264 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP---GEQGE 1320 Query: 762 PGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG-PAPQGMIMGHPPQEMRGPHPPGGLL 820 G +G+ GP QG PG + G P G I GP P GL Sbjct: 1321 KGDRGLPGP--------------QGSPGQKGEMGIPGASGPI---------GPGGPPGLP 1357 Query: 821 GHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGP 880 G GP+ +G GP GP G + QGPP G GP Sbjct: 1358 GPA-----GPKGAKGATGP-------------GGPKGEKGVQGPP----------GHPGP 1389 Query: 881 PGPQGQQNPARGPHPSQGPIPFQQ-QKTPLLGDGPRAPFNQEGQSTGPPPLIPG 933 PG Q P+P Q +KT DG R E TG P PG Sbjct: 1390 PGEVIQ------------PLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 237 bits (605), Expect = 5e-62 Identities = 253/801 (31%), Positives = 312/801 (38%), Gaps = 127/801 (15%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 G PGP G+ G G++GP+G P G GP+G +GP+GP G P G P + M GPQG Sbjct: 580 GLPGPPGEDGERGDDGEIGPRGLP---GESGPRGLLGPKGPPGIP-GPPGVRGMDGPQGP 635 Query: 678 QRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGT 737 + G GP G GPPG QG+ G QG GPQG GP G GPQG PG G G GPPG Sbjct: 636 K---GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 692 Query: 738 QGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-------------------PVSQGPLMG 778 G +GPPG +G QGP P G G PG +G++G P +G + Sbjct: 693 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 752 Query: 779 LNPRGMQGPPGPRENQGP-APQGMI--MGHP-PQEMRGPHPPGGLLG-HGPQEMRGPQEI 833 RG G PG R GP P+G G P P + G G+ G G +GP+ Sbjct: 753 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 812 Query: 834 RGMQGPPPQGSMLGP--------PQELRGPPGSQSQQGP-----PQGSLGPPPQGGMQGP 880 G G P G P+ RGP G + Q+GP G+ G G GP Sbjct: 813 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGP 872 Query: 881 PGPQGQQNPARGPHPSQGP--IPFQQQKTPLLG-DGPRAPFNQEGQSTGPPPLIPGLGQQ 937 PG +G P +GP+ GP P K L G G R +G+ TGPP +G Q Sbjct: 873 PGERGLPGP-QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK-TGPPGPPGVVGPQ 930 Query: 938 GAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGG-QDC 996 GA G P+ PGP GPP P + + G P GP P + G Sbjct: 931 GAAGETGPMGERGHPGP-----PGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDGPAGL 983 Query: 997 RGPPDRRGPHPDFPDDFSRP-------DDFHPDKRFGHRLREFEGRGGPL---------- 1039 RG P RG P P P R G GGP+ Sbjct: 984 RGFPGERG----LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 1039 Query: 1040 PQEEKWRRGGPGP--PFPPDHREFSEGD-GRGAARGPPGAWEGRRPGDERFPRDPEDPRF 1096 P +G PG P P R+ +G G GPPG GD+ DP Sbjct: 1040 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGV--AGEDGDKGEVGDPGQKGT 1097 Query: 1097 RGRREESFRRGAPPRHEGRAPPRGRDGFPG----PEDFGPEENFDA-SEEAARG------ 1145 +G + E PP G P G+ G G P GP+ +F A +E RG Sbjct: 1098 KGNKGEH----GPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPG 1153 Query: 1146 ----RDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRP 1201 + L G G G + P P G P+ DG + P PG P Sbjct: 1154 PIGLQGLPGPSGEKGETGDVGPMGPPGP-PGPRGPAGPNGADGPQGP-PGGVGNLGPPGE 1211 Query: 1202 DHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKG 1261 P + SP +QG P +R G P GP+ D G KG Sbjct: 1212 KGEPGESGSP-------GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG 1264 Query: 1262 R-------GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWG 1314 G PGP P G DG D EP G PGS P+ G +G Sbjct: 1265 NPGPVGFPGDPGP----PGEGGPRGQDGAKGDRGEDGEP--GQPGSPGPT--GENGPPGP 1316 Query: 1315 RGSNMNSGPPRRGASRGGGRG 1335 G +G P R GG+G Sbjct: 1317 LGKRGPAGSP-GSEGRQGGKG 1336 Score = 231 bits (588), Expect = 5e-60 Identities = 263/849 (30%), Positives = 327/849 (38%), Gaps = 161/849 (18%) Query: 583 LGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQG--- 639 +GP+ PG+ P+G P +P GPPG +G P GP+G +GPQG Sbjct: 597 IGPRGLPGESG----PRGLLGPKGPPGIP------GPPGVRGMDGPQGPKGSLGPQGEPG 646 Query: 640 PPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSS 699 PP QG G QG GPQG GP G PQ G GM GP G G +GPPG +G+ Sbjct: 647 PPGQQGTPGTQGLPGPQGAIGP-HGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 705 Query: 700 GPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP---------------------PGTQ 738 GP G GP G PGP+G G G G +GH G +G PG++ Sbjct: 706 GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR 765 Query: 739 GMQGPPGPRGMQGP---PHPHGIQGGPGSQGIQG----PVSQGPLMGLN----------- 780 G GP GP+G GP P P G+ G G G+ G P QGP L Sbjct: 766 GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 825 Query: 781 ----------PRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMR 828 PRG +GP GPR +GP G GPH P G G GPQ Sbjct: 826 GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 885 Query: 829 GPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQ 886 G +G GPP + + G P + RG G Q + GPP G +GP G GP G +G Sbjct: 886 GFPGPKGPPGPPGKDGLPGHPGQ-RGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944 Query: 887 QNPARGPHPSQGPIPFQQQKTPLLGDG--PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIP 944 P GP QG +P K GD P AP GP L G++G +P Sbjct: 945 PGPP-GPPGEQG-LPGTAGKEGTKGDPGPPGAPGKD-----GPAGLRGFPGERG----LP 993 Query: 945 PLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP-----EHGPERGPFRGGQDCRGP 999 G G N+G S GPP P ER SGGP GP+ P G+ +G Sbjct: 994 GTAGGPGLKGNEGPS-GPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGE--KGV 1049 Query: 1000 PDRRGPHPDFPDD-----FSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPF 1054 P +GP D P P G + E G P + K +G GPP Sbjct: 1050 PGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV-GDPGQKGTKGNKGEHGPPG 1108 Query: 1055 PPD------HREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDP-RFRGRREESFRRG 1107 PP + DG ARGP G + + R P P +G S +G Sbjct: 1109 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKG 1168 Query: 1108 -----------APPRHEGRAPPRGRDGFPGPE----DFGPE-ENFDASEEAARGRDLRGR 1151 PP G A P G DG GP + GP E + E + G ++G Sbjct: 1169 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPG--IQGE 1226 Query: 1152 -GRGTPRG--GRKGLLPTPDEFPRFEGGRKPDSWDGNR-EPGPGHEHFRDTPRPDHPPHD 1207 G PRG G KG P E P G + P DG + PGP P PP + Sbjct: 1227 PGVKGPRGERGEKGESGQPGE-PGPPGPKGPTGDDGPKGNPGPV-----GFPGDPGPPGE 1280 Query: 1208 GHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGP-G 1266 G P ++ + +G D E PG P G G GP G Sbjct: 1281 G-GPRGQDGAKGDRGED--------------------GEPGQPGSP----GPTGENGPPG 1315 Query: 1267 PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS----GTPSRGGRSGSNWGRGSNMNSG 1322 P + +G S + G D G PG G G+ G + RG + G Sbjct: 1316 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1375 Query: 1323 PPRRGASRG 1331 R + G Sbjct: 1376 QQGRPGATG 1384 Score = 229 bits (583), Expect = 2e-59 Identities = 235/775 (30%), Positives = 294/775 (37%), Gaps = 162/775 (20%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQ 675 G GP+G+ P GP+GQ GP+G G G +G G GP GPP +GLP PQ +G Sbjct: 832 GKSGPRGERGPTGPRGQRGPRGAT---GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888 Query: 676 GMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPG---PQGHIGPQGPPGPQGHLGPQ 732 G + PGP G G G PG +G G QG GP GPPG PQG G GP G +GH GP Sbjct: 889 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 948 Query: 733 GPPGTQGM---------QGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLN-PR 782 GPPG QG+ +G PGP G G P G++G PG +G+ G L G P Sbjct: 949 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 1008 Query: 783 GMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH----GPQEMRGPQEIRGMQG 838 G GP G +G A G +G P + GP P G G G + GP G+QG Sbjct: 1009 GPPGPAGSPGERGAAGSGGPIGPPGRP--GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG 1066 Query: 839 PPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNP--------- 889 P GPP + G G + + G P G G G GPPGP G P Sbjct: 1067 PVGLPGPAGPPG-VAGEDGDKGEVGDP-GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1124 Query: 890 -----ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG-LGQQGAQGRI 943 ARGP QG + + +GP P +G +PG G++G G + Sbjct: 1125 DGEPGARGP---QGHFGAKGDEGTRGFNGPPGPIGLQG--------LPGPSGEKGETGDV 1173 Query: 944 PPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRR 1003 P+ P PGP RGP GP + GP+ P GG GPP + Sbjct: 1174 GPMGPPGPPGP-----RGPA----GPNG------ADGPQGPP------GGVGNLGPPGEK 1212 Query: 1004 GPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQE-EKWRRGGPGPPFPPDHREFS 1062 G P + P ++ G GP + EK G PG P PP + + Sbjct: 1213 GE----PGESGSPG-----------IQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1257 Query: 1063 EGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRG-----APPRHEGRAP 1117 DG GP G FP DP P G R + +G P G Sbjct: 1258 GDDGPKGNPGPVG-----------FPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1306 Query: 1118 PRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGR 1177 P G +G PGP SE G+ +G G+ G P P + G Sbjct: 1307 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG--PVGPAGPAGKPG- 1363 Query: 1178 KPDSWDG-----NREPGPGHEHFRDTPRPDHPP-------------HDGH-------SPA 1212 PD G ++ PG P P PP GH P Sbjct: 1364 -PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP 1422 Query: 1213 SRERSSSLQGMDMASLPPRKR-----PWHDGP-GTSEHREMEAPGGPSEDRGGKGRGG-- 1264 + +G+ P ++ P GP G + P GP +G G GG Sbjct: 1423 GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPK 1482 Query: 1265 -----------PGPAQRV--------PKSGRSSSLDGEHHDGYHRDEPFGGPPGS 1300 PGP V PK R S+DG P GG PGS Sbjct: 1483 GEKGVQGPPGHPGPPGEVIQPLPIQMPKKTR-RSVDGSRLMQEDEAIPTGGAPGS 1536 Score = 220 bits (560), Expect = 8e-57 Identities = 204/638 (31%), Positives = 246/638 (38%), Gaps = 115/638 (18%) Query: 574 PPPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632 PP G P GP FPG P+G P +P + Q G G QG+ PPGP Sbjct: 872 PPGERGLPGPQGPNGFPG-------PKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 924 Query: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQ 690 G +GPQG G GP G G GP GPP QGLP G +G + PGP G G Sbjct: 925 GVVGPQGAA---GETGPMGERGHPGPPGPPGEQGLPGTA---GKEGTKGDPGPPGAPGKD 978 Query: 691 GPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQ 750 GP G +G G +G G G PG +G+ GP GPPGP G G +G G+ G GPPG G Q Sbjct: 979 GPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQ 1038 Query: 751 GPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQE- 809 GPP G +G PG +G GP + + G P G+ GP GP G +G P Q+ Sbjct: 1039 GPPGAAGEKGVPGEKGPIGPTGRDGVQG--PVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1096 Query: 810 ------MRGPHPPGGLLG----------------HGPQE---MRGPQEIRGMQGPP---- 840 GP P G +G GPQ +G + RG GPP Sbjct: 1097 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1156 Query: 841 ------PQGSM--------LGPP-----QELRGPPGSQSQQGPPQG--SLGPPPQGGMQG 879 P G +GPP + GP G+ QGPP G +LGPP + G G Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216 Query: 880 PPGPQGQQNP--ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPL-IPG--- 933 G G Q +GP +G Q GP+ P +G P P+ PG Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1276 Query: 934 -------LGQQGAQG-RIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGP 985 GQ GA+G R PGQ P GPP GP+ +R S G E Sbjct: 1277 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPP----GPLGKRGPAGSPGSEGRQ 1332 Query: 986 ERGPFRGGQDCRGPPDRRGP-HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEK 1044 +G G P + GP P P PD LR G G + Sbjct: 1333 GGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG----------LRGLPGSVGQQGRPGA 1382 Query: 1045 WRRGGPGPPFPPDHREFSEGDGRGAAR----------GPPGAWEGRRPGDERFPRDPEDP 1094 + GP P P GD GPPG E GD P P Sbjct: 1383 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG--EQGEKGDRGLPGPQGSP 1440 Query: 1095 RFRGRR-----EESFRRGAPPRHEGRAPPRGRDGFPGP 1127 +G G PP G A P+G G GP Sbjct: 1441 GQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGP 1478 Score = 215 bits (547), Expect = 3e-55 Identities = 239/800 (29%), Positives = 299/800 (37%), Gaps = 140/800 (17%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-QGLPRP-------- 668 GP GP G PPG QG GP G P +G G G G G GPP L P Sbjct: 402 GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 461 Query: 669 ---------------------QDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGP 707 + GP G + G GPLG G PG +G S G +GP Sbjct: 462 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES---GDLGP 518 Query: 708 QGPPGPQGHIGPQGPPGPQGHL---GPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGS 764 QGP GPQG GP G G +G G +G PG G++G G G+ G P G +G G+ Sbjct: 519 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 578 Query: 765 QGIQGPVSQGPLMG----LNPRGMQGPPGPRENQGPAPQGMIMGHP-PQEMRGPHPPGGL 819 QG+ GP + G + PRG+ G GPR GP I G P + M GP P G Sbjct: 579 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 638 Query: 820 LGHGPQEMRGPQEIRGMQG----PPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQG 875 L GPQ GP +G G P PQG+ +GP E +GP G G P GS GPP Sbjct: 639 L--GPQGEPGPPGQQGTPGTQGLPGPQGA-IGPHGE-KGPQGKPGLPGMP-GSDGPPGHP 693 Query: 876 GMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ--STGPPPLIPG 933 G +GPPG +G Q P+ GP QGP+ + + DG R +G+ G P Sbjct: 694 GKEGPPGTKGNQGPS-GP---QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGD 749 Query: 934 LGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGG 993 +G +G +G + PG D P GP + G P E+G G Sbjct: 750 IGVKGDRGEVGV------PGSRGEDGPEGPKGRTGPTGD-----PGPPGLMGEKGKL-GV 797 Query: 994 QDCRGPPDRRGP-----HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRG 1048 G P R+GP P FP R G+ GP RG Sbjct: 798 PGLPGYPGRQGPKGSLGFPGFPGASGEKG-----------ARGLSGKSGP--------RG 838 Query: 1049 GPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRF----RGRREESF 1104 GP P R G+ A+G G P ER P+ P +G Sbjct: 839 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 898 Query: 1105 RRGAP--PRHEGRAPPRGRDGFPGPED-FGPEENFDASEEAARGRDLRGRGRGTPRG--G 1159 + G P P G +G+ G PGP GP+ A E G RG P G G Sbjct: 899 KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG--AAGETGPMGE----RGHPGPPGPPG 952 Query: 1160 RKGLL-----------PTPDEFPRFEGGRKPDSWDGNRE-PG-PGHEHFRDTPRPDHPPH 1206 +GL P P P +G + G R PG G + P PP Sbjct: 953 EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 1012 Query: 1207 DGHSPASRERSSSLQGMDMASLPPRKRPWHDG-PGTSEHREMEAPGGPSEDRGGKGRGGP 1265 SP R + S + P RP G PG + + + GP G G GP Sbjct: 1013 PAGSPGERGAAGS-----GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGP 1067 Query: 1266 -------GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS-------GTPSRGGRSGS 1311 GP + G + G ++ GPPG G P G G Sbjct: 1068 VGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGE 1127 Query: 1312 NWGRGSNMNSGPPRRGASRG 1331 RG + G +RG Sbjct: 1128 PGARGPQGHFGAKGDEGTRG 1147 Score = 191 bits (484), Expect = 5e-48 Identities = 142/385 (36%), Positives = 169/385 (43%), Gaps = 54/385 (14%) Query: 599 QGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGP 658 QG P + ++ MGPPGP G P GP G GPQGPP G GP G G G Sbjct: 1158 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1217 Query: 659 QGPP--QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGH 716 G P QG P + G +G + G G GP GP GP G GP+G+ GP G PG G Sbjct: 1218 SGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGP 1277 Query: 717 IGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHP---HGIQGGPGSQGIQGPVSQ 773 G GP G G G +G G G G PGP G GPP P G G PGS+G QG Sbjct: 1278 PGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG---- 1333 Query: 774 GPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH-GPQEMRGPQE 832 +G +G PG +G P + GP P G G GP +RG Sbjct: 1334 -------GKGAKGDPG------------AIGAPGK--TGPVGPAGPAGKPGPDGLRGLPG 1372 Query: 833 IRGMQGPPPQGSMLGPPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQNPA 890 G QG P GPP + GPPG +G +G G P G+ GPPG QG++ Sbjct: 1373 SVGQQGRPGATGQAGPPGPV-GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDR 1431 Query: 891 RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG-LGQQGAQGRIPPLNPG 949 P P P + P GP P G PP +PG G +GA+G Sbjct: 1432 GLPGPQGSPGQKGEMGIP-GASGPIGP--------GGPPGLPGPAGPKGAKG-------A 1475 Query: 950 QGPGPNKGDS--RGPPNHHMGPMSE 972 GPG KG+ +GPP H GP E Sbjct: 1476 TGPGGPKGEKGVQGPPG-HPGPPGE 1499 Score = 148 bits (373), Expect = 4e-35 Identities = 122/354 (34%), Positives = 143/354 (40%), Gaps = 86/354 (24%) Query: 584 GPQPFPGQ-GPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPP 641 GP FPG GP + P+G + Q G PGP G+ PPGP G+ GP G P Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326 Query: 642 LHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGP 701 G +G G +G +G P G G GP GP GP G PGP G G Sbjct: 1327 ------GSEGRQGGKGAKGDP----------GAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1370 Query: 702 QGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGG 761 G +G QG PG G GP GP GP G G +G G +G +G PG G+ GPP G QG Sbjct: 1371 PGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPP---GEQGE 1427 Query: 762 PGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG-PAPQGMIMGHPPQEMRGPHPPGGLL 820 G +G+ GP QG PG + G P G I GP P GL Sbjct: 1428 KGDRGLPGP--------------QGSPGQKGEMGIPGASGPI---------GPGGPPGLP 1464 Query: 821 GHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGP 880 G GP+ +G GP GP G + QGPP G GP Sbjct: 1465 GPA-----GPKGAKGATGP-------------GGPKGEKGVQGPP----------GHPGP 1496 Query: 881 PGPQGQQNPARGPHPSQGPIPFQQ-QKTPLLGDGPRAPFNQEGQSTGPPPLIPG 933 PG Q P+P Q +KT DG R E TG P PG Sbjct: 1497 PGEVIQ------------PLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 234 bits (597), Expect = 4e-61 Identities = 248/759 (32%), Positives = 299/759 (39%), Gaps = 137/759 (18%) Query: 616 QMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHG 673 Q+GPPG G PG G GPQGPP G +GF G G G P G P G Sbjct: 1267 QVGPPGDPGL---PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPG 1323 Query: 674 PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGH-MGPQGP--PGPQGHIGPQGPPGPQGHL- 729 +G PGP G G +GP GP+G G G +G +GP PG +G GP GPPGP+G L Sbjct: 1324 LKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLG 1383 Query: 730 --GPQGPPGTQG--MQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-PVSQGPLMGLNPRGM 784 GP+GPPG G M+G G RG +GPP P PG G+ G P S G P+G Sbjct: 1384 DPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG------PQGP 1437 Query: 785 QGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGS 844 GPPG + +G + G G P Q P PG GP GP+ RG GP + Sbjct: 1438 VGPPGKKGEKGDSEDG-APGLPGQ----PGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAG 1492 Query: 845 MLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQ----NPARGPHPS---- 896 G RGPPG +G P G G P G +GPPGP G+Q P R P+ Sbjct: 1493 EKGE----RGPPGPAGSRGLP-GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGP 1547 Query: 897 --QGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG----------LGQQGAQGRIP 944 GP + +K + GPR +G+ P ++PG G G GR Sbjct: 1548 AVAGP---KGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAG 1604 Query: 945 PLNPG-QGPGPNKGD--SRGPPNHHMGPMSERRHEQSGGP--EHGPERGP----FRGGQD 995 P PG GP KGD GPP GP+ R + G + GP P G + Sbjct: 1605 P--PGDSGPPGEKGDPGRPGPP----GPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERG 1658 Query: 996 CRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGR-GGPLPQEEKWRRGGPGPPF 1054 RG P RGP + D +D GR G P K RG PGPP Sbjct: 1659 LRGAPGVRGPVGEKGDQGDPGED---------------GRNGSPGSSGPKGDRGEPGPPG 1703 Query: 1055 PPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEG 1114 PP GR G PGA E PGD R E P RG + + GAP Sbjct: 1704 PP---------GRLVDTG-PGAREKGEPGD----RGQEGP--RGPKGDPGLPGAPGE--- 1744 Query: 1115 RAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTP-RGGRKGLLPTPDEF-PR 1172 RG +GF GP GP+ + RG RG P GR GL P P Sbjct: 1745 ----RGIEGFRGPP--GPQ-----GDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPS 1793 Query: 1173 FEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRK 1232 G + D R+ PG + P P PP P + L G + P + Sbjct: 1794 GPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKP-GEDGKPGLNGKNGEPGDPGE 1852 Query: 1233 RPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDE 1292 G S E GP +RG G GP +P Sbjct: 1853 DGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP------------------ 1894 Query: 1293 PFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 GPPG G P G +G RG + G RG Sbjct: 1895 --VGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERG 1931 Score = 218 bits (555), Expect = 3e-56 Identities = 267/882 (30%), Positives = 334/882 (37%), Gaps = 152/882 (17%) Query: 571 QIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG 630 Q+ PP G P P P P S +G + + P + + G PG G G Sbjct: 1267 QVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKG 1326 Query: 631 PQGQMGPQGPPLHQGGGGPQGFMGPQGP--QGPPQGLPRPQDMHGPQGMQRHPGPHGPL- 687 G GP+G P +G GP+G G G G GLP + GP G PGP GPL Sbjct: 1327 SPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSG---PPGPRGPLG 1383 Query: 688 --GPQGPPGPQGSS--GPQGHMGPQGPPGP-QGHIGP--------QGPPGPQGHLGP--- 731 GP+GPPG G++ G +G G +GPPGP +G I P G PGPQG +GP Sbjct: 1384 DPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGK 1443 Query: 732 -----------------QGPPGTQGMQGPP---GPRGMQGPPHPHGIQGGPGSQGIQGPV 771 G PG QG +GPP GP+G +G P P G G G +G GP Sbjct: 1444 KGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPA 1503 Query: 772 SQGPLMGL----NPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH-GPQE 826 L G+ +G +GPPGP QG + G P P G G GP Sbjct: 1504 GSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAG 1563 Query: 827 MRGPQEIRGMQGPPPQGSML-------GPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQG 879 RG ++G +GPP G +L G P + RGP G + GPP G GPP + G G Sbjct: 1564 PRGATGVQGERGPP--GLVLPGDPGPKGDPGD-RGPIGLTGRAGPP-GDSGPPGEKGDPG 1619 Query: 880 PPGPQGQQNPAR-----GPHPSQGP-----IPFQQQKTPLLG-DGPRAPFNQEGQSTGPP 928 PGP G P G +GP +P + + L G G R P ++G P Sbjct: 1620 RPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPG 1679 Query: 929 PLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSR----GPPNHHMGPMSERRHEQSGGPEHG 984 G+ G+ G P PGP R GP G +R E GP+ Sbjct: 1680 E----DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGD 1735 Query: 985 P-------ERG--PFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGR 1035 P ERG FRG +G P RGP + D P D R G L G Sbjct: 1736 PGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGD--RGPPGL--DGRSG--LDGKPGA 1789 Query: 1036 GGPL-PQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPG----AWEGRRPGDERFPRD 1090 GP P + G PG P R G GPPG E +PG + Sbjct: 1790 AGPSGPNGAAGKAGDPGRDGLPGLR---GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGE 1846 Query: 1091 PEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPG----------PEDFGPE-ENF--- 1136 P DP GR+ E GA R EGR P+G G PG P GP + F Sbjct: 1847 PGDPGEDGRKGEKGDSGASGR-EGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV 1905 Query: 1137 --DASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFE-----GGRKP-------DSW 1182 + RG +G P G +GL P P + G K ++W Sbjct: 1906 PGGTGPKGDRGETGSKGEQGLP--GERGLRGEPGSVPNVDRLLETAGIKASALREIVETW 1963 Query: 1183 D---GNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGP 1239 D G+ P P + P P L+G R P GP Sbjct: 1964 DESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG-------DRGDPGPQGP 2016 Query: 1240 GTSEHREMEAPGGPSEDRGGKGRGG----PGPAQRVPKSGRSSSLDGEHHDGYHRDEPFG 1295 E P GPS G G+ G PG A V ++GR G ++ Sbjct: 2017 PGLALGE-RGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRD 2075 Query: 1296 GPPG-SGTPSRGGRSG-----SNWGRGSNMNSGPPRRGASRG 1331 GPPG GTP G G G G + GPP ++G Sbjct: 2076 GPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKG 2117 Score = 211 bits (538), Expect = 3e-54 Identities = 257/813 (31%), Positives = 319/813 (39%), Gaps = 140/813 (17%) Query: 610 MPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQG---PPQGLP 666 +P+ + GP G G+ PPG +G P G P +G G +G GPQGP G +G P Sbjct: 1971 LPVPERRRGPKGDSGEQGPPGKEG---PIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027 Query: 667 RPQDMHGPQG---MQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQG---PPGPQGHIGPQ 720 P + G G + PG G +G G PG +G G +G G QG PPG G GP Sbjct: 2028 GPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPP 2087 Query: 721 GPPGPQ--------GHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVS 772 GPPGP+ G G QGPPG +G +G PG G QGP G+ G G +G GP Sbjct: 2088 GPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG 2147 Query: 773 QGPLMGL-NPRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGP 830 Q GL RGM GP G QGP P G + GH P PPG GP +GP Sbjct: 2148 QDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD-----PGPPGAPGLAGPAGPQGP 2202 Query: 831 QEIRGMQGP--PPQGSMLGPPQE--LRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQ 886 ++G G PP + GP L GPPG GP QGS G P Q G G PG G+ Sbjct: 2203 SGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGP-QGSPGLPGQVGETGKPGAPGR 2261 Query: 887 QNPARGPHPSQGP--IPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGL----GQQGAQ 940 A G +G +P +P L GP P + G + P + GL G++GA Sbjct: 2262 DG-ASGKDGDRGSPGVP----GSPGL-PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAP 2315 Query: 941 GRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSER----RHEQSGGPEHGPERGP-----FR 991 G + G+ PG KGD RG P GP E+ R + G P ++G F+ Sbjct: 2316 GGLAGDLVGE-PGA-KGD-RGLP----GPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFK 2368 Query: 992 G--GQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGG 1049 G G G P GP P D P G F G+ GP RG Sbjct: 2369 GDPGVGVPGSPGPPGP-PGVKGDLGLPGLPGAPGVVG-----FPGQTGP--------RGE 2414 Query: 1050 PGPPFPPDHREFSEGDGRGAARGPPGA----WEGRRPGDERFPRDPEDPRF-----RGRR 1100 G P P R + GR GP G PG D DP RG R Sbjct: 2415 MGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGER 2474 Query: 1101 EESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENF--DASEEAARGRDLRGRGRGTPRG 1158 E RG R G+ PRG G PG E+ A + +G G PRG Sbjct: 2475 GEPGIRGEDGR-PGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRG 2533 Query: 1159 --------GRKGLLPTPDEFPRFEGGRKPDSWDGNREPG-------PGHEHF---RDTPR 1200 G +GL D+ PR + G P EPG PG + P Sbjct: 2534 AKGDMGERGPRGL--DGDKGPRGDNG-DPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPG 2590 Query: 1201 PDHPPHDGHSPASRERSSSLQGM--DMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRG 1258 P D SP ++ ++G D+ + PR G R ++ G ++G Sbjct: 2591 AAGIPGDPGSPG-KDGVPGIRGEKGDVGFMGPR--------GLKGERGVKGACGLDGEKG 2641 Query: 1259 GKGRGGP----------GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS-------- 1300 KG GP G G+S + E G D F G PG Sbjct: 2642 DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKG 2701 Query: 1301 --GTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 GTP GG G + GS GPP RG Sbjct: 2702 ERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRG 2734 Score = 167 bits (423), Expect = 6e-41 Identities = 148/464 (31%), Positives = 189/464 (40%), Gaps = 76/464 (16%) Query: 575 PPSSGTPLLGPQPFPGQGPMSQIPQ-----GFQQPHPSQQMPMN-MAQMGPPGPQGQFRP 628 P S G P GP G + +P GF P Q P M Q GP G +G P Sbjct: 2376 PGSPGPP--GPPGVKGDLGLPGLPGAPGVVGF----PGQTGPRGEMGQPGPSGERGLAGP 2429 Query: 629 PGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQ-GLPRPQDMHGPQGMQRH---PGPH 684 PG +G GP GPP G GP G G +G +G P GLP P+ G G++ PG Sbjct: 2430 PGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQE 2489 Query: 685 GPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGH----IGPQGPPGPQGHLGPQGPPGTQGM 740 GP G GPPG +G G +G +G G G +G +GP GP G +G +G +GP G G Sbjct: 2490 GPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGD 2549 Query: 741 QGP------PGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGL----NPRGMQGPPGP 790 +GP PG +G +G P G G PG +G+ GP Q G+ G G PG Sbjct: 2550 KGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGI 2609 Query: 791 RENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQ 850 R +G MG P+ ++G G G + G + +G GPP + + G Sbjct: 2610 RGEKGDVG---FMG--PRGLKGERGVKGACG-----LDGEKGDKGEAGPPGRPGLAGHKG 2659 Query: 851 ELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTP 908 E+ G PG Q G P +G +GP G G PGP+G Q G +G TP Sbjct: 2660 EM-GEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQ----GEKGERG--------TP 2706 Query: 909 LLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMG 968 +G P G G G P P GP + G Sbjct: 2707 GIGGFP--------------------GPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERG 2746 Query: 969 PMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDD 1012 P ER G P ERG +G GP +G DD Sbjct: 2747 PPGERVVGAPGVPGAPGERGE-QGRPGPAGPRGEKGEAALTEDD 2789 Score = 157 bits (398), Expect = 5e-38 Identities = 132/403 (32%), Positives = 172/403 (42%), Gaps = 65/403 (16%) Query: 574 PPPSSGTP-LLGPQPFPGQ-GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP 631 PP G P LGP PG GP + P +P + G PG +G+ PG Sbjct: 2429 PPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQ 2488 Query: 632 QGQMGPQGPPLHQGGGGPQGFMGPQGPQGP------------PQGLPRPQDMHGPQGMQR 679 +G G GPP +G G +G +G G +G P+G GP+G+ Sbjct: 2489 EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLD- 2547 Query: 680 HPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG 739 G GP G G PG +GS G G G G PG +G +GPQG PG G G G PG G Sbjct: 2548 --GDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG 2605 Query: 740 MQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQ 799 + G G +G G P G++ G +G++G G+ G G + GP + Sbjct: 2606 VPGIRGEKGDVGFMGPRGLK---GERGVKGAC-----------GLDGEKGDKGEAGPPGR 2651 Query: 800 GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQ 859 + GH EM P PG G + + GP+ RG G P GP +G G + Sbjct: 2652 PGLAGH-KGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQP------GP----KGDQGEK 2700 Query: 860 SQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAP 917 ++G P G GP G GPPGP G P RGP QG QK G R P Sbjct: 2701 GERGTPGIGGFPGPSGNDGSAGPPGPPGSVGP-RGPEGLQG------QK------GERGP 2747 Query: 918 FNQEGQSTGPPPLIPGL-GQQGAQGRIPPLNPGQGPGPNKGDS 959 G+ P +PG G++G QGR P GP KG++ Sbjct: 2748 ---PGERVVGAPGVPGAPGERGEQGRPGP----AGPRGEKGEA 2783 Score = 143 bits (360), Expect = 1e-33 Identities = 190/627 (30%), Positives = 233/627 (37%), Gaps = 74/627 (11%) Query: 718 GPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ--GP 775 G +G PG G G GPPG G+ PG G GP P G G +G G + P Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPGL---PGRTGAPGPQGPPGSATAKGERGFPGADGRPGSP 1310 Query: 776 LMGLNPRGMQGPPGPRENQG-PAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIR 834 NP G G PG + + G P P+G P E RGP P G E P ++ Sbjct: 1311 GRAGNP-GTPGAPGLKGSPGLPGPRG-----DPGE-RGPRGPKG-------EPGAPGQVI 1356 Query: 835 GMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPP--PQGGMQGPPGPQGQQNPARG 892 G +GP G P GPPG + G P G GPP P M+G G +G++ P Sbjct: 1357 GGEGPGLPGRKGDPGPS--GPPGPRGPLGDP-GPRGPPGLPGTAMKGDKGDRGERGP--- 1410 Query: 893 PHPSQGPIPFQQQKTPLL-----GDGPRAPFNQEGQSTGPPPLIPGL-GQQGAQGRIPPL 946 P P +G I + P L GP P ++G+ PGL GQ G+ G P Sbjct: 1411 PGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPR 1470 Query: 947 NPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPH 1006 P GP KGD RG P GP+ E + GP P RG G P +GP Sbjct: 1471 GPPGAIGP-KGD-RGFP----GPLGEAGEKGERGP---PGPAGSRGLPGVAGRPGAKGPE 1521 Query: 1007 PDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDG 1066 P R + R G GP K +G GP P G Sbjct: 1522 GP-PGPTGRQGEKGEPGRPGD-----PAVVGPAVAGPKGEKGDVGPAGP------RGATG 1569 Query: 1067 RGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPG 1126 RGPPG PGD P DP RG + R G PP G +G G PG Sbjct: 1570 VQGERGPPGL---VLPGD---PGPKGDPGDRGPIGLTGRAG-PPGDSGPPGEKGDPGRPG 1622 Query: 1127 PE-DFGPEENFDASEEAARGRDLRGRGRGTP-RGGRKGLLPTPD-EFPRFEGGRKPDSWD 1183 P GP E +G + G P + G +GL P P E G + D + Sbjct: 1623 PPGPVGPRGR--DGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGE 1680 Query: 1184 GNREPGPGH---EHFRDTPRPDHPPHD--GHSPASRERSSSLQGMDMASLPPRKRPWHDG 1238 R PG + R P P PP P +RE+ P+ P G Sbjct: 1681 DGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPG 1740 Query: 1239 -PGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGP 1297 PG P GP D G +G G + P S LDG+ P G Sbjct: 1741 APGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGK-PGAAGPSGPNGAA 1799 Query: 1298 PGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 +G P R G G +G SGPP Sbjct: 1800 GKAGDPGRDGLPGLRGEQGLPGPSGPP 1826 Score = 82.4 bits (202), Expect = 3e-15 Identities = 149/535 (27%), Positives = 189/535 (35%), Gaps = 102/535 (19%) Query: 839 PPPQGSMLGPPQELRGPPGS---QSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHP 895 P P+ + P+ +G PG + Q GPP G G P + G GP GP G A+G Sbjct: 1242 PRPEPCPVYCPKGQKGEPGEMGLRGQVGPP-GDPGLPGRTGAPGPQGPPGSAT-AKGERG 1299 Query: 896 SQGPIPFQQQKTPLLGDG-PRAPFNQEGQSTGP-PPLIPGL-GQQGAQGRIPPLNPGQ-G 951 G DG P +P G++ P P PGL G G G P +PG+ G Sbjct: 1300 FPG------------ADGRPGSP----GRAGNPGTPGAPGLKGSPGLPG--PRGDPGERG 1341 Query: 952 PGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPD 1011 P KG+ G P +G + G P GP P G + G P RGP P P Sbjct: 1342 PRGPKGEP-GAPGQVIGGEGPGLPGRKGDP--GPSGPP--GPRGPLGDPGPRGP-PGLPG 1395 Query: 1012 DFSRPDDFHPDKRFGHRLREFEGRGGPLPQEE--KWRRGGPGP--PFPPDHREFSEGDGR 1067 + D D+ G R G GG P E G PGP P P ++ +GD Sbjct: 1396 TAMKGDK--GDR--GERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSE 1451 Query: 1068 GAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGP 1127 A G PG P P +G R PP G P+G GFPGP Sbjct: 1452 DGAPGLPG--------------QPGSPGEQGPR-------GPP---GAIGPKGDRGFPGP 1487 Query: 1128 EDFGPEENFDASEEAARGRDLRG-RGRGTPRGGRKGLLPTPDEFPRFEGGRKPD-SWDGN 1185 E+ A R L G GR +G PT + + E GR D + G Sbjct: 1488 LGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGP 1547 Query: 1186 REPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLP-PRKRPWHDGP-GTSE 1243 GP E + D P + G+ + P P+ P GP G + Sbjct: 1548 AVAGPKGE------KGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTG 1601 Query: 1244 HREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS--- 1300 GP ++G GR PGP V GR + + +G D G G Sbjct: 1602 RAGPPGDSGPPGEKGDPGR--PGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGL 1659 Query: 1301 ----------------GTPSRGGRSGS------NWGRGSNMNSGPPRRGASRGGG 1333 G P GR+GS RG GPP R G G Sbjct: 1660 RGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPG 1714 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 233 bits (594), Expect = 9e-61 Identities = 275/873 (31%), Positives = 341/873 (39%), Gaps = 171/873 (19%) Query: 574 PPPSSGTP----LLGPQPFPGQ-GPMSQI-PQGFQQPHPSQQMPMNMAQMGPPGPQGQFR 627 PP G P L GP PG G + + P G+ P G G G Sbjct: 800 PPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPK------------GMKGLMGSVG 847 Query: 628 PPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----QGLPRPQDMHGPQGMQRHPG 682 PG +G G QG P G G GF G +G QG P +G P P G +G PG Sbjct: 848 EPGLKGDKGEQGVP---GVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPG 904 Query: 683 PHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQG 742 P GP G G GP G +GP+G +G PG +G GP+G GP+G GP GPPG G++G Sbjct: 905 PPGPEGFPGDIGPPGDNGPEGM---KGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEG 961 Query: 743 PPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGL-------------NPRGMQGPPG 789 PG +G G P G++G PG G GPV + MG RGM GPPG Sbjct: 962 QPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPG 1021 Query: 790 PRENQGPAPQGMIMGHP-------------PQEMRGPHPPGGLLG-------HGPQEMRG 829 P P+G MGHP PQ G P G+ G GP G Sbjct: 1022 V-----PGPKGS-MGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAG 1075 Query: 830 PQEIRGMQGPP-PQGSMLGPPQE----LRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQ 884 Q RG++GPP PQG P Q+ RG GS+ G P G GPP G+ G PGPQ Sbjct: 1076 EQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIP-GPSGPPGTKGLPGEPGPQ 1134 Query: 885 GQQNPARGPHPSQGP--IPFQQQKTPLLGD-GPRAPFNQEGQSTGPPPLIPGLGQQGAQG 941 G Q P GP GP P + L G+ G + G + G LI G+ G +G Sbjct: 1135 GPQGPI-GPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLG-TPGEQGLIGQRGEPGLEG 1192 Query: 942 RIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP-------EHGPERGPFRGGQ 994 P+ P G ++GD GP H E + G P GPE + G+ Sbjct: 1193 DSGPMGP-DGLKGDRGDP-GPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGE 1250 Query: 995 DCR----------------GPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGP 1038 R G P GP P P P G +G P Sbjct: 1251 KGRTGAKGAKGYQGQLGEMGVPGDPGP-PGTPGPKGSRGSLGPTGAPG----RMGAQGEP 1305 Query: 1039 LPQEEKWRRGGPGPPFPPDHR-EFSEGDGRGAARGPPGAWEGRRPGDERFPR-DPEDPRF 1096 +G GP PP + E E G A GPPG R P +R R +P DP + Sbjct: 1306 GLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGY 1365 Query: 1097 RGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRG----RG 1152 G+ RG P + +G+ G G+PGP+ E + A RG +G Sbjct: 1366 PGQEGVQGLRGKPGQ-QGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQG 1424 Query: 1153 RGTPRG--GRKGL--LPTPDEFPRFEG--GRKPDSWDGNREPGP-GHEHFRDTPRPDHPP 1205 PRG GR+GL + PD P +G G++ + D + +PGP G R P P Sbjct: 1425 LPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGD-DGDPGPMGPAGKRGNPGVAGLP 1483 Query: 1206 HDGHSPASRERSSSLQGMDMASLPPRKR--------PWHDG-PGT----SEHREMEAPG- 1251 P + S G+ PP KR P + G PG+ + EM PG Sbjct: 1484 GAQGPPGFKGES----GLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGM 1539 Query: 1252 -------GPSEDRGGKGRGGP-GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTP 1303 GP D G KG GP GP + K G P G SG P Sbjct: 1540 AGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG--------------PLGILGPSGLP 1585 Query: 1304 SRGGRSGSNWGRGSNMNSGPPRRGASRGGGRGR 1336 G GS G GPP G RGR Sbjct: 1586 GPKGDKGSRGDWGLQGPRGPP-------GPRGR 1611 Score = 206 bits (523), Expect = 2e-52 Identities = 258/848 (30%), Positives = 313/848 (36%), Gaps = 156/848 (18%) Query: 573 QPPPSSGTP---LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPP 629 QP PS T +L P F P G+ H + P + MGPPGP+G P Sbjct: 579 QPQPSQQTTPALVLAPAQFLSSSPRPT-SSGYSIFHLAGSTPFPLL-MGPPGPKGDCGLP 636 Query: 630 GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGP 689 GP G G G P G +GP+GPP GP G +PG GP G Sbjct: 637 GPPGLPGLPGIP------------GARGPRGPP----------GPYG---NPGLPGPPGA 671 Query: 690 QGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGM 749 +G G G S + H G +G G G G GPPG +GH G GP G G QG PGP G Sbjct: 672 KGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGS 731 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMGL----------NPRGMQGPPGPRENQG-PAP 798 G G QG PG G GP +GL RG+ G PG R G P Sbjct: 732 PGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGF 791 Query: 799 QGMI--MGHP-----PQEMRGPHPPG--GLLGH----GPQEMRGPQEIRGMQGPPPQGSM 845 G+ G P P E+ P PPG GL+G GP GP+ ++G+ G + + Sbjct: 792 PGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGL 851 Query: 846 LGPPQE-----LRGPPGSQSQQGP--------------PQGSLGPPPQGGMQGPPGPQGQ 886 G E + G PG Q +G P G +G G GPPGP+G Sbjct: 852 KGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGF 911 Query: 887 QNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGP--PPLIPGL-GQQGAQGRI 943 GP GP + + GPR EG GP PP PGL GQ G +G Sbjct: 912 PGDI-GPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDE-GPMGPPGAPGLEGQPGRKGF- 968 Query: 944 PPLNPG-QGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDR 1002 P PG G GD P GP+ E+ G P +G + GPP Sbjct: 969 -PGRPGLDGVKGEPGDPGRP-----GPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022 Query: 1003 RGP-----HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPD 1057 GP HP P P + P G RG P + K RRG GP P Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGPPG-------SRGPPGMRGAKGRRGPRGPDGPAG 1075 Query: 1058 HREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAP--PRHEGR 1115 + G +GPPG +GR P P G R RG P P G Sbjct: 1076 EQ------GSRGLKGPPGP-QGR-------PGRPGQQGVAGERGHLGSRGFPGIPGPSGP 1121 Query: 1116 APPRGRDGFPGPE----------DFGPEENFDASEEAARGRDLRGRGRGTPRG--GRKGL 1163 +G G PGP+ + GP+ A E + +G P G G +GL Sbjct: 1122 PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181 Query: 1164 LPTPDEFPRFEGGRKPDSWDGNR----EPGPGHEHFRDTPR----PDHPPHDGHSPASR- 1214 + E P EG P DG + +PGP EH D PP R Sbjct: 1182 IGQRGE-PGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRG 1240 Query: 1215 -ERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPG--GPSEDRGGKG-RGGPGPAQR 1270 E S QG + + + G EM PG GP G KG RG GP Sbjct: 1241 PEGKSGKQGEKGRTGAKGAKGYQGQLG-----EMGVPGDPGPPGTPGPKGSRGSLGPTGA 1295 Query: 1271 VPKSGRSSSLDGEHHDGYHRDEPFGGPPG-SGTPSRGGRSGSNWGRGSNMNSGPPRRGAS 1329 + G +DG+ GPPG G G G GPP Sbjct: 1296 PGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGK--------AEGPPGPPGD 1347 Query: 1330 RG--GGRG 1335 RG G RG Sbjct: 1348 RGPVGDRG 1355 Score = 202 bits (515), Expect = 1e-51 Identities = 227/747 (30%), Positives = 288/747 (38%), Gaps = 160/747 (21%) Query: 584 GPQPFPGQ--GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP---------- 631 GP+ FPG P P+G + ++ +P Q+GP G +G PPG Sbjct: 907 GPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRK 966 Query: 632 --------QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--------QGLPRPQDMHGPQ 675 G G G P G G QGFMG G G P +G+ P + GP+ Sbjct: 967 GFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPK 1026 Query: 676 GMQRHPG------------PHGP---------------LGPQGPPGPQGSSGPQGHMGPQ 708 G HPG P GP GP+GP GP G G +G GP Sbjct: 1027 GSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPP 1086 Query: 709 GPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQ 768 GP G G G QG G +GHLG +G PG G GPPG +G+ G P P G QG G G Sbjct: 1087 GPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEM 1146 Query: 769 GPVSQGPLMGLNPRGMQGPPGPRENQG----PAPQGMI--MGHPPQE-MRGPHPPGGLLG 821 GP +GP + G+ G G + + G P QG+I G P E GP P GL G Sbjct: 1147 GP--KGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKG 1204 Query: 822 -------HGPQEMRGPQEIRGMQGPPPQGSMLGPP--QELRGPPGSQSQQGPP------- 865 G +G + + G GPP GPP +RGP G +QG Sbjct: 1205 DRGDPGPDGEHGEKGQEGLMGEDGPP------GPPGVTGVRGPEGKSGKQGEKGRTGAKG 1258 Query: 866 ----QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLG--DGPRAPFN 919 QG LG G GPPG G + P+ P Q P L DG + Sbjct: 1259 AKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVG 1318 Query: 920 QEGQSTGPPPLIPGLGQQGAQGRI--PPLNPG-QGPGPNKGDSRGPPNHHMGPMSE---- 972 GPP G+QG G+ PP PG +GP ++GD RG P P E Sbjct: 1319 ----PLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGD-RGEPGDPGYPGQEGVQG 1373 Query: 973 --RRHEQSGGPEH-GPERGPF-RGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHR 1028 + Q G P H GP P +G + GP ++G + P R Sbjct: 1374 LRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433 Query: 1029 LREFEGRGGP--LP--------QEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWE 1078 + EG GP LP Q E+ G PGP P R G A+GPPG Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGF-- 1491 Query: 1079 GRRPGDERFPRDPEDPRFRGRREESFRRGAP-----PRHEGRAPPRGRDGFPGPED-FGP 1132 G+ P P G+R R G P P +G+ G GFPG FGP Sbjct: 1492 ---KGESGLPGQLGPP---GKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGP 1545 Query: 1133 EENFDASEEAARGRDLRGRGRGTPRG-----GRKGLL-------PTPDEFPRFEGGRKPD 1180 + D+ +G PRG G++G++ P+ P+ + G + D Sbjct: 1546 K---------GPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGD 1596 Query: 1181 -SWDGNR-EPGPGHEHFRDTPRPDHPP 1205 G R PGP R P P PP Sbjct: 1597 WGLQGPRGPPGP-----RGRPGPPGPP 1618 Score = 195 bits (495), Expect = 3e-49 Identities = 197/632 (31%), Positives = 241/632 (38%), Gaps = 158/632 (25%) Query: 582 LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP------QGQM 635 ++GP PG P+G HP MP M G PGPQG GP +G+ Sbjct: 1016 MMGPPGVPG-------PKG-SMGHPG--MPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRR 1065 Query: 636 GPQGPPLHQGGGGPQGFMGPQGPQGPP--------------------QGLPRPQDMHGPQ 675 GP+GP G G +G GP GPQG P G+P P G + Sbjct: 1066 GPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTK 1125 Query: 676 GMQRHPGPHGPLGPQGPPGPQGSSGP---------------QGHMGPQGPPGPQGHIGPQ 720 G+ PGP GP GP GPPG G GP +G +GP G PG QG IG + Sbjct: 1126 GLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQR 1185 Query: 721 GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGG------PGSQGIQGPVSQG 774 G PG +G GP GP G +G +G PGP G G G+ G PG G++GP + Sbjct: 1186 GEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKS 1245 Query: 775 PLMG----------------LNPRGMQGPPGPRENQGPAPQGMIMGHP--PQEMRGPHPP 816 G L G+ G PGP GP +G P M P Sbjct: 1246 GKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEP 1305 Query: 817 G--GLLGH----GPQEMRGPQEIRGMQGPPPQGSMLGPPQEL--RGPPGSQSQQGPP--- 865 G G GH GP GP+ +G QG G GPP RGP G + +G P Sbjct: 1306 GLAGYDGHKGIVGPLGPPGPKGEKGEQGE--DGKAEGPPGPPGDRGPVGDRGDRGEPGDP 1363 Query: 866 --------QGSLGPPPQGGMQGPPGPQGQQNP-----ARGPHPSQGPI--PFQQQKTPLL 910 QG G P Q G G PGP+G P A GP QG P ++ L Sbjct: 1364 GYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQ 1423 Query: 911 G-DGPRAPFNQEG-QSTGPPPLIPGL-------GQQGAQGRIPPL-------NPG----- 949 G GPR ++G + P +PG G+QG G P+ NPG Sbjct: 1424 GLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLP 1483 Query: 950 --QGPGPNKGDS-----------------RGPPNHHMGPMSERRHEQSG----------- 979 QGP KG+S G P + P S+ + SG Sbjct: 1484 GAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLF 1543 Query: 980 GPEHGPERGPFRGGQDCRGPPDRRGPHPDF-PDDFSRPDDFHPDKRFGHRLREFEGRGGP 1038 GP+ P F+G Q RGPP G P P P + R G GP Sbjct: 1544 GPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGL-PGPKGDKGSRGDWGLQGP 1602 Query: 1039 LPQEEKWRRGGPGPPFPPDHREFSEGDGRGAA 1070 + RG PGPP PP + D GAA Sbjct: 1603 --RGPPGPRGRPGPPGPPGGPIQLQQDDLGAA 1632 Score = 164 bits (416), Expect = 4e-40 Identities = 159/464 (34%), Positives = 190/464 (40%), Gaps = 102/464 (21%) Query: 574 PPPSSGTPLLGPQPFPG-QGPMSQI----PQGFQQPHPSQQMPMNMAQMGPPGPQGQ--- 625 P P T + GP+ G QG + +G+Q +P + G PGP+G Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289 Query: 626 FRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP------------QGLPRPQDMHG 673 P G G+MG QG P G G +G +GP GP GP +G P P G Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRG 1349 Query: 674 P------QGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQG 727 P +G PG G G QG G G G GH GP+G PGP+G G +GP G QG Sbjct: 1350 PVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQG 1409 Query: 728 HLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGP 787 G G G QG+QG PGPRG+ G GI G G G G Q +G QG Sbjct: 1410 KAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQ--------QGEQGD 1461 Query: 788 PGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLG 847 G P P G P RG GL G +GP +G G P Q LG Sbjct: 1462 DG-----DPGPMG------PAGKRGNPGVAGLPG-----AQGPPGFKGESGLPGQ---LG 1502 Query: 848 PP--QELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQ 905 PP + G G QG P GS G P G G PG G P +GP G I F+ Sbjct: 1503 PPGKRGTEGRTGLPGNQGEP-GSKGQPGDSGEMGFPGMAGLFGP-KGP---PGDIGFKGI 1557 Query: 906 KTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDS------ 959 + GPR GPP L +G++G G + L P PGP KGD Sbjct: 1558 Q------GPR----------GPPGL---MGKEGIVGPLGILGPSGLPGP-KGDKGSRGDW 1597 Query: 960 -----RGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRG 998 RGPP GP + G P GP GP + QD G Sbjct: 1598 GLQGPRGPP----GPRG-----RPGPP--GPPGGPIQLQQDDLG 1630 Score = 47.4 bits (111), Expect = 9e-05 Identities = 169/742 (22%), Positives = 221/742 (29%), Gaps = 189/742 (25%) Query: 741 QGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGL-----NPRGMQGPPGPRENQG 795 Q P GP Q P Q G++ + P +G PRG P P + Q Sbjct: 243 QSPLGPLFSQDSGRPFTFQSDLALLGLENLTTATPALGSLPAGRGPRGTVAPATPTKPQR 302 Query: 796 PAP----QGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQE 851 +P Q M +G P Q P P L + P + G P Sbjct: 303 TSPTNPHQHMAVGGPAQT---PLLPAKLSASNALDPMLPASVGGSTRTPR---------- 349 Query: 852 LRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQ---------GPIPF 902 P +Q Q + P+ P P P + PHP+Q +P Sbjct: 350 ---PAAAQPSQKITATKI---PKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPT 403 Query: 903 QQQKTPLLGDGP-------RAPFNQEGQSTGPPP---------------LIPGLGQQGAQ 940 Q+Q P P P + PPP IP L + A+ Sbjct: 404 QKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAK 463 Query: 941 ---------------GRIPPLNP-GQGPGPNKGDSRG--PPNHHMGPMS----------- 971 + PP P P G +R PP + P S Sbjct: 464 ITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAV 523 Query: 972 --------------ERRHEQSGGPEHGPERG-PFRGGQDCRGPP-----DRRGPHPDFPD 1011 + GP+ P + P R G+ R P R P P Sbjct: 524 PTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPS 583 Query: 1012 DFSRPDDFHPDKRF----------GHRLREFEGRGG-PLPQEEKWRRGGPGPPFPPDHRE 1060 + P +F G+ + G PL +G G P PP Sbjct: 584 QQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPG 643 Query: 1061 FSEGDGRGAARGPPGAW-EGRRPGDERFPRDPEDPRFR-GRREESFR--RGAPPRHEGRA 1116 G RGPPG + PG DP G+ + + G P Sbjct: 644 LPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPG 703 Query: 1117 PP--RGRDGFPGPEDFGPEENFDASEEAARGRDLRGR-------GRGTPRGGRKGLLPTP 1167 PP +G G+PGP E+ E + + GR G P+G R G + P Sbjct: 704 PPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSR-GYIGLP 762 Query: 1168 DEF--PRFEGGRKPDSWDGNR----EPG-PGHEHFRDTPRPDHPPHDGHSPASRERSSSL 1220 F P +G R G R PG PG R P D P + P + Sbjct: 763 GLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPG----PPGV 818 Query: 1221 QGM--DMASLPPRKRPWHDG----------PG-TSEHREMEAPG-----GPSEDRGGKG- 1261 G+ D+ L P P G PG + E PG G D+G +G Sbjct: 819 PGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGL 878 Query: 1262 ------RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG-SGTPSRGGRSGSNWG 1314 RG PGP +V G F GPPG G P G G N Sbjct: 879 PGFPGARGKPGPLGKVGDKGSIG---------------FPGPPGPEGFPGDIGPPGDNGP 923 Query: 1315 RGSNMNSGPPRRGASRGGGRGR 1336 G M P RG G RG+ Sbjct: 924 EG--MKGKPGARGLP--GPRGQ 941 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 232 bits (592), Expect = 2e-60 Identities = 242/802 (30%), Positives = 308/802 (38%), Gaps = 139/802 (17%) Query: 583 LGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPG---PQGQFRPPGPQGQMGPQG 639 +GP PG P G Q H SQ +P +G PG P G PG G GP G Sbjct: 631 VGPPGEPG-------PPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLG 683 Query: 640 PPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSS 699 P H+G G +G GP G GPP G P P+ + G G + G G G G PG +G Sbjct: 684 HPGHEGPTGEKGAQGPPGSAGPP-GYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDV 742 Query: 700 GPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQ 759 G +G G G PGP+G GP+GP G G G +GPPG+ G +G G G+ G P G + Sbjct: 743 GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPK 802 Query: 760 GGPGSQGIQGPVSQGPLMGLNPR----GMQGPPGPRENQG-------PAPQGMI------ 802 G G G GP+ + G + G +GPPG R +G P P+G + Sbjct: 803 GSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAP 862 Query: 803 -----MGHP----PQEMRGPHPPGGLLGH----GPQEMRGPQEIRGMQGPPPQGSMLGPP 849 G P P GP P G G G RG +G GPP +LGP Sbjct: 863 GIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGP- 921 Query: 850 QELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHP--SQGPIPFQQQKT 907 Q G G ++GPP G GPP + G+ G G +G + P P +GP + Sbjct: 922 QGKTGEVGPLGERGPP-GPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPG 980 Query: 908 PLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPG-PNKGDSRGPPNHH 966 P G G P +G P P+ G G+ G PL P G G P + S GP Sbjct: 981 PKGGPGDPGPTGLKGDKGPPGPV----GANGSPGERGPLGPAGGIGLPGQSGSEGP---- 1032 Query: 967 MGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPD--DFSRPDDFHPDKR 1024 +GP ++ GP + G GPP GP + D D P Sbjct: 1033 VGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAP-------- 1084 Query: 1025 FGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGD 1084 GH+ + + +G P + RG G P PP DG RGPPG + Sbjct: 1085 -GHKGSKGD-KGDAGPPGQPGIRGPAGHPGPPG------ADGAQGRRGPPGLF------- 1129 Query: 1085 ERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAAR 1144 G++ + RG G P G G PGP P E + + + Sbjct: 1130 -------------GQKGDDGVRG----FVGVIGPPGLQGLPGP----PGEKGEVGDVGSM 1168 Query: 1145 GRDLRGRGRGTPRG--GRKGLLPTPDEFPRFEG-----GRKPDSWDGNREPGPGHEHFRD 1197 G G PRG G G TP P G G K + D +PGP Sbjct: 1169 GP----HGAPGPRGPQGPTGSEGTPG-LPGGVGQPGAVGEKGERGDAG-DPGP------- 1215 Query: 1198 TPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKR--PWHDGP-GTSEHREMEAPGGPS 1254 P P G E+ S G A+ PP K+ P DG G+ + GP Sbjct: 1216 ---PGAPGIPGPKGDIGEKGDS--GPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPP 1270 Query: 1255 EDRGGKG-RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPS----RGGRS 1309 D G G G PG + G + G G + GPPG PS R GR Sbjct: 1271 GDPGVSGIDGSPG------EKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGRE 1324 Query: 1310 GSNWGRGSNMNSGPPRRGASRG 1331 G +G GPP R G Sbjct: 1325 GEKGAKGEPGPDGPPGRTGPMG 1346 Score = 229 bits (585), Expect = 1e-59 Identities = 259/860 (30%), Positives = 331/860 (38%), Gaps = 128/860 (14%) Query: 569 VEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQM-GPPGPQGQFR 627 ++ I+ PP GT ++ P F G G P FQQ + M GPPGP G Sbjct: 432 IDGIRGPP--GTVIMMPFQFAG-GSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTG 488 Query: 628 PPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--------------QGLPRPQDMHG 673 PGP G G G +G GPQG G QGP GPP +GLP G Sbjct: 489 RPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKG 548 Query: 674 PQGMQRHPG------PHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQG 727 +G PG G G G PGP G G +G GP GP G G GP+G GP+G Sbjct: 549 DRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRG 608 Query: 728 HLGPQGPPGTQGMQGPPGPRGMQGP---PHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGM 784 GP G PG G+ G PG +G GP P P G QG GSQG+ GP QG L+G G Sbjct: 609 SPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGP--QG-LIG--TPGE 663 Query: 785 QGPPGPRENQGPAPQGMIMGHP----PQEMRGPHPPGGLLG----HGPQEMRGPQEIRGM 836 +GPPG G +GHP P +G P G G GP+ ++G RG+ Sbjct: 664 KGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGL 723 Query: 837 QGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPS 896 QG + G P +G G + QG P G P G GP GP+GQ A P Sbjct: 724 QGEKGEKGEDGFP-GFKGDVGLKGDQGKP----GAPGPRGEDGPEGPKGQAGQAGEEGPP 778 Query: 897 QGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRI--PPLNPGQGPGP 954 + P L P P +G P PL P +G++G G+ P L +GP Sbjct: 779 GSAGEKGKLGVPGLPGYPGRP-GPKGSIGFPGPLGP-IGEKGKSGKTGQPGLEGERGPPG 836 Query: 955 NKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFS 1014 ++G+ RG P P + Q G P G +G P +GP P FP Sbjct: 837 SRGE-RGQPGATGQPGPKGDVGQDGAP----------GIPGEKGLPGLQGP-PGFPGPKG 884 Query: 1015 RPDDFHPDKRFGHRLRE----FEGRGGPL-------PQEEK------WRRGGPGPPFPPD 1057 P D R GH + F+G+ GP PQ + RG PGPP PP Sbjct: 885 PPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPG 944 Query: 1058 HREFSEGDGRGAAR---GPPG--AWEGRR-----PGDERFPRDPEDPRFRGRREESFRRG 1107 + +GR A+ GPPG EG PG + P DP +G + G Sbjct: 945 EQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVG 1004 Query: 1108 A--PPRHEGRAPPRGRDGFPGPE-DFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLL 1164 A P G P G G PG GP A ++ +RG RG P K + Sbjct: 1005 ANGSPGERGPLGPAGGIGLPGQSGSEGPVG--PAGKKGSRGE------RGPPGPTGKDGI 1056 Query: 1165 PTPDEFPRFEGGRKPDSWDGNREP--GPGHEHFRDTPRPDHPP----------HDGHSPA 1212 P P G P +G++ PGH+ + PP H G A Sbjct: 1057 PGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGA 1116 Query: 1213 -------------SRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGG 1259 ++ ++G PP + PG GP G Sbjct: 1117 DGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGP 1176 Query: 1260 KGRGGPGPAQRVP-KSGRSSSLDGEHHDGYHRDEPFGGPPGS-GTPSRGGRSGSNWGRGS 1317 +G GP ++ P G G D GPPG+ G P G G G Sbjct: 1177 RGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGP 1236 Query: 1318 NMNSGPPRRGASRG--GGRG 1335 + +GPP + G G +G Sbjct: 1237 SGAAGPPGKKGPPGEDGAKG 1256 Score = 218 bits (556), Expect = 2e-56 Identities = 225/632 (35%), Positives = 264/632 (41%), Gaps = 131/632 (20%) Query: 578 SGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMG 636 +G P L G + PG P QP P + + A G PG +G GP G G Sbjct: 823 TGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAP-GIPGEKGLPGLQGPPGFPG 881 Query: 637 PQGPPLHQGGGGPQGFMGPQGPQG--PPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPG 694 P+GPP HQG G G G +G G G P P + GPQG G GPLG +GPPG Sbjct: 882 PKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKT---GEVGPLGERGPPG 938 Query: 695 PQGSSGPQGHMGPQGPPGPQGHIGPQGP------------PGPQGHLGPQGPPGTQGMQG 742 P G G QG G +G G +G +GP GP PGP+G G GP G +G +G Sbjct: 939 PPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKG 998 Query: 743 PPGPRGMQGPP---HPHGIQGG---PGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG- 795 PPGP G G P P G GG PG G +GPV GP RG +GPPGP G Sbjct: 999 PPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPV--GPAGKKGSRGERGPPGPTGKDGI 1056 Query: 796 PAPQGMIMGHPPQEMRGPHPPGGLLGH-GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRG 854 P P G + P GP G G G +G + +G GPP Q + GP G Sbjct: 1057 PGPLGPL---GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH-PG 1112 Query: 855 PP---GSQSQQGPP--------------QGSLGPPPQGGMQGPPGPQGQQNP--ARGPHP 895 PP G+Q ++GPP G +GPP G+ GPPG +G+ + GPH Sbjct: 1113 PPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHG 1172 Query: 896 SQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRI----------PP 945 + GP GP+ P E G P L G+GQ GA G PP Sbjct: 1173 APGP------------RGPQGPTGSE----GTPGLPGGVGQPGAVGEKGERGDAGDPGPP 1216 Query: 946 LNPGQGPGP-----NKGDS-----RGPPNHHMGPMSERRHEQSGGP-----EHGPERGPF 990 PG PGP KGDS GPP GP E + S GP + GP P Sbjct: 1217 GAPGI-PGPKGDIGEKGDSGPSGAAGPPG-KKGPPGEDGAKGSVGPTGLPGDLGPPGDPG 1274 Query: 991 RGGQDCR-----GPPDRRGPHPDFPDDFSRPD-DFHPDKR--FGHRLREFEGRGGPLPQE 1042 G D P D GP P P P P KR GH R EGR G Sbjct: 1275 VSGIDGSPGEKGDPGDVGGPGP--PGASGEPGAPGPPGKRGPSGHMGR--EGREG----- 1325 Query: 1043 EKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREE 1102 EK +G PGP PP G ARGPPG R G E P G E Sbjct: 1326 EKGAKGEPGPDGPPGR------TGPMGARGPPG-----RVGPEGLRGIP------GPVGE 1368 Query: 1103 SFRRGAPPRHEGRAPPRGRDGFPGPE-DFGPE 1133 GAP + G P G G PG + D GP+ Sbjct: 1369 PGLLGAPGQ-MGPPGPLGPSGLPGLKGDTGPK 1399 Score = 217 bits (553), Expect = 5e-56 Identities = 205/634 (32%), Positives = 258/634 (40%), Gaps = 97/634 (15%) Query: 575 PPSSGTP-LLGPQPFPG-QGPMSQIPQGFQQPHPSQQMPMNM-AQMGPPGPQGQFRPPGP 631 P G P L GP FPG +GP + + HP Q+ + Q GPPGP G P G Sbjct: 865 PGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGK 924 Query: 632 QGQMGP---------QGPPLHQGGGGPQGFMGPQGPQGPPQGLPRP-----QDMHGPQGM 677 G++GP GPP QG G +G G +G GPP L + + GP+G Sbjct: 925 TGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGG 984 Query: 678 QRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGP------PGPQGHIGPQGPPGPQGHLGP 731 PGP G G +GPPGP G++G G GP GP PG G GP GP G +G G Sbjct: 985 PGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGE 1044 Query: 732 QGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPR 791 +GPPG G G PGP G GPP G G G +G G + G +G GPPG Sbjct: 1045 RGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG--APGHKGSKGDKGDAGPPGQP 1102 Query: 792 ENQGPAPQGMIMGHP----PQEMRGPHPPGGLLGH-GPQEMRG------PQEIRGMQGPP 840 +GPA GHP +G P GL G G +RG P ++G+ GPP Sbjct: 1103 GIRGPA------GHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPP 1156 Query: 841 PQGSMLGPPQEL--RGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPS 896 + +G + G PG + QGP +G+ G P G G G +G++ A P P Sbjct: 1157 GEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPP 1216 Query: 897 QGP-IPFQQQKTPLLGD----------GPRAPFNQEGQ--STGP--------PPLIPGL- 934 P IP + GD G + P ++G S GP PP PG+ Sbjct: 1217 GAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS 1276 Query: 935 ------GQQGAQGRI----PPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHG 984 G++G G + PP G+ P RGP H MG R E+ E G Sbjct: 1277 GIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGH-MG-REGREGEKGAKGEPG 1334 Query: 985 PERGPFRGG-QDCRGPPDRRGPHP--------DFPDDFSRPDDFHPDKRFGHR-LREFEG 1034 P+ P R G RGPP R GP P P P G L +G Sbjct: 1335 PDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKG 1394 Query: 1035 RGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPG-AWEGRRPGDERFPRDPED 1093 GP + EK G G PP G +GPPG + PG P Sbjct: 1395 DTGP--KGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGP 1452 Query: 1094 PRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGP 1127 P G + +G+P G PRG G GP Sbjct: 1453 PGVAGPLGQKGSKGSP----GSMGPRGDTGPAGP 1482 Score = 180 bits (457), Expect = 7e-45 Identities = 132/366 (36%), Positives = 168/366 (45%), Gaps = 45/366 (12%) Query: 617 MGPPGPQGQFRPPGPQGQ------MGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQD 670 +GPPG QG PPG +G+ MGP G P G GPQG G +G G P G+ +P Sbjct: 1144 IGPPGLQGLPGPPGEKGEVGDVGSMGPHGAP---GPRGPQGPTGSEGTPGLPGGVGQPGA 1200 Query: 671 MHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG 730 + G +G + G GP G G PGP+G G +G GP G GP G GP G G +G +G Sbjct: 1201 V-GEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVG 1259 Query: 731 PQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGL-NPRGMQGPPG 789 P G PG G G PG G+ G P G +G PG G GP G P G +GP G Sbjct: 1260 PTGLPGDLGPPGDPGVSGIDGSP---GEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSG 1316 Query: 790 PRENQGPAPQGMIMGHPPQEMRGPHPPGGLLG----HGPQEMRGPQEIRGMQGPPPQGSM 845 +G + G P GP P G G GP GP+ +RG+ GP + + Sbjct: 1317 HMGREGREGEKGAKGEP-----GPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGL 1371 Query: 846 LGPPQELRGPPGSQSQQGPP--QGSLGPPPQGG------MQGPPGPQGQQNPARGPHPSQ 897 LG P ++ GPPG G P +G GP + G + GPPG G++ +G Q Sbjct: 1372 LGAPGQM-GPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGD-QGLPGVQ 1429 Query: 898 GPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKG 957 GP P GP P G GPP + LGQ+G++G + P GP Sbjct: 1430 GP------PGPKGDPGPPGPIGSLGHP-GPPGVAGPLGQKGSKGSPGSMGPRGDTGP--- 1479 Query: 958 DSRGPP 963 GPP Sbjct: 1480 --AGPP 1483 Score = 176 bits (445), Expect = 2e-43 Identities = 231/794 (29%), Positives = 287/794 (36%), Gaps = 139/794 (17%) Query: 654 GPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGP 713 G +G +G P + + Q GP G G GP GP GPPG G GP G G G PG Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGI 432 Query: 714 QGHIGP---------------------------------------QGPPGPQGHLGPQGP 734 G GP +GPPGP G G GP Sbjct: 433 DGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGP 492 Query: 735 ---------PGTQGMQGPPGPRGMQGPPHPH---GIQGGPGSQGIQG-PVSQGPLMGLNP 781 G +G +GP GPRG+QGP P G G PG+ G +G P GP Sbjct: 493 VGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGF 552 Query: 782 RGMQGPPGPRENQG-------PAPQGM-----IMGHP-PQEMRGPHPPGGLLG-HGPQEM 827 G+ G PG + +G P P G G P P G P GLLG G Sbjct: 553 DGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGP 612 Query: 828 RGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGP-----PQGSLGPP----PQG--- 875 G + G+ G P +GPP E GPPG Q G PQG +G P P G Sbjct: 613 TGRPGVTGIDGAPGAKGNVGPPGE-PGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPG 671 Query: 876 -----GMQGPPGPQGQQNP-----ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ-- 923 G GP G G + P A+GP S GP + + G R ++G+ Sbjct: 672 IPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKG 731 Query: 924 STGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEH 983 G P +G +G QG+ PG PGP D P G E G P Sbjct: 732 EDGFPGFKGDVGLKGDQGK-----PG-APGPRGEDGPEGPKGQAGQAGE-----EGPPGS 780 Query: 984 GPERGPFRGGQDCRGPPDRRGPHPD--FPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQ 1041 E+G G G P R GP FP + + G E E RG P + Sbjct: 781 AGEKGKL-GVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGE-RGPPGSR 838 Query: 1042 EEKWRRGGPGPPFPPDHREFSEGD-GRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRR 1100 E+ + G G P P +GD G+ A G PG E PG + P P G + Sbjct: 839 GERGQPGATGQPGP-------KGDVGQDGAPGIPG--EKGLPGLQGPPGFPGPKGPPGHQ 889 Query: 1101 EESFRRGAPPRHEGRAPPRGRDGFPGPED-FGPE----ENFDASEEAARGRDLRGRGRGT 1155 + R G P + G +G+ G PGP GP+ E E G +G Sbjct: 890 GKDGRPGHPGQ-RGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGL 948 Query: 1156 P----RGGRKGLLPTPDEFPRFEGGRKPDSWDGNR-EPG-PGHEHFRDTPRPDHPPHDGH 1209 P R G KG L P + EG + G + PG PG + P P Sbjct: 949 PGLEGREGAKGELGPPGPLGK-EGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANG 1007 Query: 1210 SPASRERSSSLQGMDMASLPPRKRPWHDGP-GTSEHREMEAPGGPSEDRGGKG----RGG 1264 SP R G+ + + P GP G R P GP+ G G G Sbjct: 1008 SPGERGPLGPAGGIGLPGQSGSEGP--VGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGP 1065 Query: 1265 PGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS-GTPSRGGRSGSNWGRGSNMNSGP 1323 PG A + G + H G D+ GPPG G G G G+ GP Sbjct: 1066 PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP 1125 Query: 1324 PRRGASRG--GGRG 1335 P +G G RG Sbjct: 1126 PGLFGQKGDDGVRG 1139 Score = 174 bits (440), Expect = 7e-43 Identities = 127/340 (37%), Positives = 156/340 (45%), Gaps = 41/340 (12%) Query: 583 LGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFR---------PPGPQG 633 +GP PG P+G Q P S+ P +G PG G+ PPG G Sbjct: 1168 MGPHGAPG-------PRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPG 1220 Query: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPP 693 GP+G +G GP G GP G +GPP G + GP G+ GP G G G Sbjct: 1221 IPGPKGDIGEKGDSGPSGAAGPPGKKGPP-GEDGAKGSVGPTGLPGDLGPPGDPGVSGID 1279 Query: 694 GPQGSSGPQGHMGPQGPPGPQGHIGPQGPPG---PQGHLGPQGPPGTQGMQGPPGPRGMQ 750 G G G G +G GPPG G G GPPG P GH+G +G G +G +G PGP G Sbjct: 1280 GSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPP 1339 Query: 751 GPPHPHGIQGGPGS------QGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMG 804 G P G +G PG +GI GPV + L+G G GPPGP GP+ + G Sbjct: 1340 GRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAP--GQMGPPGPL---GPSGLPGLKG 1394 Query: 805 HP-PQEMRGPHPPGGLLGH-GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQ 862 P+ +G GL+G G +G Q + G+QGPP GPP GP GS Sbjct: 1395 DTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPP----GPIGSLGHP 1450 Query: 863 GPPQGSLGPPPQGGMQGPPG---PQGQQNPARGPHPSQGP 899 GPP G GP Q G +G PG P+G PA P P P Sbjct: 1451 GPP-GVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489 Score = 155 bits (392), Expect = 2e-37 Identities = 101/263 (38%), Positives = 122/263 (46%), Gaps = 34/263 (12%) Query: 574 PPPSSGTP-------LLGPQPFPGQ-GPMSQIPQGFQQPHPSQQM-PMNMAQMGPPGPQG 624 PP G P +GP PG GP P ++ P ++ GPPG G Sbjct: 1242 PPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASG 1301 Query: 625 QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----QGLPRPQDMHGPQGMQR 679 + PGP G+ GP G +G G +G G GP GPP G P GP+G++ Sbjct: 1302 EPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRG 1361 Query: 680 HPGPHGPLG------PQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQG 733 PGP G G GPPGP G SG G G GP G +GHIG G GP G G +G Sbjct: 1362 IPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKG 1421 Query: 734 PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPV----SQGPLMGLNPRGMQGPPG 789 G G+QGPPGP+G GPP P G G PG G+ GP+ S+G + PRG GP G Sbjct: 1422 DQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAG 1481 Query: 790 PRENQGPAPQGMIMGHPPQEMRG 812 P P P G P E+ G Sbjct: 1482 P-----PGPPG-----APAELHG 1494 Score = 72.8 bits (177), Expect = 2e-12 Identities = 153/559 (27%), Positives = 187/559 (33%), Gaps = 112/559 (20%) Query: 823 GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPG 882 G GP + R + P + P +G G + Q GPP G QG G Sbjct: 346 GDDSTMGP-DFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVG 404 Query: 883 PQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRA--------PFNQEGQSTGPPPLIPGL 934 P G P P P P P + DG R PF G S PP+ Sbjct: 405 PSGPPGPPGFPGDPGPPGPAGLPGIPGI-DGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQ 463 Query: 935 GQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQ 994 Q A + L+ PGP R P G + E + GP+ GP RG Q Sbjct: 464 AQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQ-GP-----RGLQ 517 Query: 995 DCRGPPDRRGP--HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRR--GGP 1050 GPP R G P P D P R F+G G LP E+ R G Sbjct: 518 GPHGPPGRVGKMGRPGADGARGLPGDTGPKGD-----RGFDGLPG-LPGEKGQRGDFGHV 571 Query: 1051 GPPFPPDHREFSEGDGRGAARGPPG-AWEGRRPGDERFPRDPEDPRFRGRREESFRRGAP 1109 G P PP DG A GPPG + PG PR PR Sbjct: 572 GQPGPPGE------DGERGAEGPPGPTGQAGEPG----PRGLLGPR------------GS 609 Query: 1110 PRHEGRAPPRGRDGFPGPE-DFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPD 1168 P GR G DG PG + + GP E G+ +G P G +GL+ TP Sbjct: 610 PGPTGRPGVTGIDGAPGAKGNVGP-----PGEPGPPGQQGNHGSQGLP--GPQGLIGTP- 661 Query: 1169 EFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHP-PHDGHSPASRERSSSLQGMDMAS 1227 G + P PG+ P D P H GH + E+ + QG ++ Sbjct: 662 ---------------GEKGP-PGNPGIPGLPGSDGPLGHPGHEGPTGEKGA--QGPPGSA 703 Query: 1228 LPPRKRPWHDGPGTSEHREME----------------------------APGGPSED--R 1257 PP GTS +R ++ APG ED Sbjct: 704 GPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPE 763 Query: 1258 GGKGRGGPGPAQRVPKS-GRSSSLDGEHHDGY-HRDEPFG--GPPGS-GTPSRGGRSGSN 1312 G KG+ G + P S G L GY R P G G PG G G+SG Sbjct: 764 GPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKT 823 Query: 1313 WGRGSNMNSGPPRRGASRG 1331 G GPP RG Sbjct: 824 GQPGLEGERGPPGSRGERG 842 Score = 55.1 bits (131), Expect = 5e-07 Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 7/98 (7%) Query: 582 LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPP 641 L+GP G+ +P G Q P P GPPGP G PGP G GP G Sbjct: 1410 LIGPPGEAGEKGDQGLP-GVQGP------PGPKGDPGPPGPIGSLGHPGPPGVAGPLGQK 1462 Query: 642 LHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQR 679 +G G G G GP GPP P ++HG + +R Sbjct: 1463 GSKGSPGSMGPRGDTGPAGPPGPPGAPAELHGLRRRRR 1500 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 221 bits (562), Expect = 5e-57 Identities = 254/797 (31%), Positives = 304/797 (38%), Gaps = 122/797 (15%) Query: 574 PPPSSGTP----LLGPQPFPG-QGPMSQIPQGFQQPHPSQQ--MPMNMAQMGPPGPQGQF 626 PP + GTP L GP PG GP + GF P P +P +GP G +G Sbjct: 723 PPGAPGTPGRIGLEGPPGPPGFPGPKGE--PGFALPGPPGPPGLPGFKGALGPKGDRGFP 780 Query: 627 RPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP----QGLPRPQDMHGPQGMQRHPG 682 PPGP G+ G G P +G GP G GP GP G P QG P P + GP G PG Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ---PG 837 Query: 683 PHGPLGPQGPPGPQGSS--GPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG- 739 HG G +G PGP G GP G G G PG G IGP G PG G G G PGT+G Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 897 Query: 740 --MQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-PVSQGPLMGLNPRGMQGPPGPRENQGP 796 M GPPGP G G P G+ G G G+QG P GP +G G PGP P Sbjct: 898 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP-----P 952 Query: 797 APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPP 856 P + E P PG + GP+ +G+ G P Q + G P L GPP Sbjct: 953 GPMDPNLLGSKGEKGEPGLPG------IPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPP 1005 Query: 857 GSQSQQGPP--QGSLGPPPQGGMQGP---PGPQGQQNPARGPHPSQGPIPFQQQKTPLLG 911 G + G P G +GPP G G PGPQG + P P +P Q L G Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP-----PGPSGVPGQPGSPGLPG 1060 Query: 912 DGPRAPFNQEGQSTGPPPLIPGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPM 970 Q+G P GL G G +G P PG P S G P P Sbjct: 1061 --------QKGDKGDPGISSIGLPGLPGPKGE--PGLPGYPGNPGIKGSVGDPGLPGLPG 1110 Query: 971 SERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLR 1030 + Q G P GP G + GPP G P + P GH Sbjct: 1111 TPGAKGQPGLPGFPGTPGP-PGPKGISGPPGNPG----------LPGEPGPVGGGGHP-- 1157 Query: 1031 EFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPG--AWEGRRPGDERFP 1088 G P P EK + G G P P + G G GPPG G++ GD P Sbjct: 1158 -----GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLSGQK-GDGGLP 1210 Query: 1089 RDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDL 1148 P +P G + E G P G P G G PGP GP+ N + GR Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFP----GVQGPPGPPGSPGPALEGPKGN--PGPQGPPGRPG 1264 Query: 1149 RGRGRGTP----RGGRKGLLPTPDE-----FPRFEGGRKPDSWDGNREPG-PGHEHFRDT 1198 G P GG KG P + P +G + P GN PG PG + Sbjct: 1265 LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN--PGRPGLNGMKGD 1322 Query: 1199 PR-PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSE---HREMEAPGGPS 1254 P P P G S S+ + + P P GP + PG P Sbjct: 1323 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1382 Query: 1255 EDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWG 1314 + G KG GP Q +P GPPG P R G G + Sbjct: 1383 QP-GLKGLPGPQGPQGLPGPT--------------------GPPGD--PGRNGLPGFDGA 1419 Query: 1315 RGSNMNSGPPRRGASRG 1331 G + G P + +RG Sbjct: 1420 GGRKGDPGLPGQPGTRG 1436 Score = 209 bits (532), Expect = 1e-53 Identities = 246/791 (31%), Positives = 303/791 (38%), Gaps = 114/791 (14%) Query: 616 QMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQG--PPQGLPRPQDMHG 673 + G PG +G PG G GP+GPP +G G G GP GP+G P GLP Sbjct: 49 ERGFPGLEGH---PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP------- 98 Query: 674 PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQG 733 G PG G G G PGPQG G G G +G PG G G QGPPGP G G +G Sbjct: 99 --GFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 734 PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVS-QGPLMGLNPRGMQGPPGPRE 792 PG+ M PGP+G G P P GIQG PG GI GP+ GP + P G G PGP+ Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 793 NQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEM-----RGPQEIRGMQGPPPQGSMLG 847 N G QG Q ++GP P G + + + +G Q + G +GPP + G Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 848 PPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG-QQNPARGPHPSQGPIPFQQQK 906 PP G G + +QG P G G P + G G PG G +P P + Q+ Sbjct: 277 PPGPPGGEKGEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335 Query: 907 T-PLLGDGPRAPFNQEGQSTGPPPLI--PGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGP 962 T P G P G + G I PGL G++G +G P PGP GP Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395 Query: 963 PNHHMGPMSERRHEQSGGPEHGPERGP-----FRGGQDCRGPPDRRGPHPDFPDDFSRPD 1017 P P ER + GP GP G GPP GPH D+ P Sbjct: 396 PGPPGFP-GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454 Query: 1018 DFHPDKRFGHRLREFE---------------GRGGPLPQEEKWRRGGPGPP----FPPDH 1058 P G + + E G G P + G PGPP FP Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514 Query: 1059 REFSEGDGRG--AARGPPGAWEGRRPGDERFP---RDPED----PRFRGRREESFRRGAP 1109 E + G G PGA PG FP +P D P +G + E GAP Sbjct: 515 GEKGQAGATGPKGLPGIPGA-----PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 1110 --PRHEGRAPPRGRDGFPGPE----------DFGPEENFDASEEAARGRDLRGRGRGTP- 1156 P G G G PGP+ + GP N + G G P Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 1157 ---RGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPG-------PGHEHFRDTPRPDHPPH 1206 G +G+ P + P G K D +PG PG + D P P Sbjct: 630 PVGEKGIQGVAGNPGQ-PGIP-GPKGDPGQTITQPGKPGLPGNPGRD--GDVGLPGDPGL 685 Query: 1207 DGHS-----PASRERSSSLQGMDMASLP-PRKRPWHDG----PGTSEHREMEAPGGPSED 1256 G P S+ + G+ + P P+ P G PGT +E P GP Sbjct: 686 PGQPGLPGIPGSK-GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744 Query: 1257 RGGKGRGG---PGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNW 1313 G KG G PGP G +L G D F GPP G P R G G Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGAL------GPKGDRGFPGPP--GPPGRTGLDGLPG 796 Query: 1314 GRGSNMNSGPP 1324 +G +G P Sbjct: 797 PKGDVGPNGQP 807 Score = 208 bits (529), Expect = 3e-53 Identities = 211/662 (31%), Positives = 254/662 (38%), Gaps = 108/662 (16%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP-- 631 PP G+P + P P P S G M MGPPGP G PG Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917 Query: 632 ----------QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHP 681 QGQ G GP +G G G GP GP P L + G G+ P Sbjct: 918 VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP--NLLGSKGEKGEPGLPGIP 975 Query: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQ 741 G GP G QG PG G G G G GPPGP+G+ G PG G +GP G GT G Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN---PGLPGQPGLIGPPGLKGTIGDM 1032 Query: 742 GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGM 801 G PGP+G++GPP P G+ G PGS G+ G G++ G+ G PGP+ G Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPG------ 1086 Query: 802 IMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQ 861 + G+P PG G + G G +G P G P GPPG Sbjct: 1087 LPGYPGN-------PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP----GPPG---- 1131 Query: 862 QGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQE 921 P+G GPP G+ G PGP G G HP Q P ++ K DG P Q+ Sbjct: 1132 ---PKGISGPPGNPGLPGEPGPVG-----GGGHPGQPGPPGEKGKPG--QDGIPGPAGQK 1181 Query: 922 GQSTGP------PPLIPGLGQQGAQGRIP--PLNPGQGPGPNKGDSRGPPNHHMGPMSER 973 G+ P PP +PGL Q G +P P NPG PGP +G P H P + Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL-PGP-----KGEPGFHGFPGVQG 1235 Query: 974 RHEQSGGPEHGPERGPFRGGQDCRGPPDRRG-PHPDFPDDFSRPDDFHPDKRFGHRLREF 1032 G P GP +G +GPP R G P P+ P Sbjct: 1236 PPGPPGSP--GPALEGPKGNPGPQGPPGRPGLPGPEGPPG-------------------L 1274 Query: 1033 EGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRD-- 1090 G GG K +G PG P P G +G PG RPG D Sbjct: 1275 PGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG-----RPGLNGMKGDPG 1324 Query: 1091 -PEDPRFRGRREESFRRGA--PPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGR- 1146 P P F G + S G+ P G P G G PGP DA G+ Sbjct: 1325 LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQP 1384 Query: 1147 DLRG-RGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWD--GNREPGPGHEHFRDTPRPDH 1203 L+G G P+G LP P P G +D G R+ PG T D Sbjct: 1385 GLKGLPGPQGPQG-----LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDG 1439 Query: 1204 PP 1205 PP Sbjct: 1440 PP 1441 Score = 194 bits (492), Expect = 6e-49 Identities = 253/853 (29%), Positives = 306/853 (35%), Gaps = 205/853 (24%) Query: 618 GPPGPQGQFRPPG------PQGQMGPQGPPLHQGGGGPQ------------------GFM 653 GPPGP+G PPG G G G H G GPQ GF Sbjct: 84 GPPGPKGIRGPPGLPGFPGTPGLPGMPG---HDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 654 GPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGP 713 G QGP GPP G+P + G M PGP G G GPPG QG GP G GP GPPGP Sbjct: 141 GLQGPPGPP-GIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 714 QGHIGPQGP---PGPQGHL-----GPQGPPGTQGMQGPPGP----------------RGM 749 G +GP GP PGP+G++ GP+G G QG+QGPPGP +G Sbjct: 200 PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGD 259 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMG-LNPRGMQGPPGPR-------ENQGPAPQGM 801 QG P G +G PG GI+GP GP G +G QG PG R EN P G+ Sbjct: 260 QGLP---GDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314 Query: 802 --IMGHPPQEMR----------GPHPPGGLL----GHG--------------PQEMRGPQ 831 G+P + R GP P GL+ G G P E +G + Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGER 373 Query: 832 EIRGMQGP-----PPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQ 886 G+QGP PP +++GPP GPPG ++G +G GPP + GPPG GQ Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPP----GPPGFPGERG-QKGDEGPPGI-SIPGPPGLDGQ 427 Query: 887 QNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPL 946 P P GP GP P + E GPP G +G QG Sbjct: 428 PGAPGLPGP-PGPA------------GPHIPPSDEICEPGPPGPPGSPGDKGLQGE---- 470 Query: 947 NPGQGPGPNKGDS---------RGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCR 997 QG +KGD+ GPP P G P E+G G + Sbjct: 471 ---QGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ-AGATGPK 526 Query: 998 GPPDRRGP--HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFP 1055 G P G P FP P D + F G G +K G PG P Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGD----------ILTFPGMKG-----DKGELGSPGAPGL 571 Query: 1056 PDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAP------ 1109 P DG GP G G ER P P +P G G P Sbjct: 572 PGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP--PGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 1110 ----PRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLP 1165 +G A G+ G PGP+ + + G R G P G G LP Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP--GDPG-LP 686 Query: 1166 TPDEFPRFEGGRKPDSWDGNREPG-PGHEHFRDTPRP------------DHPPHDGHSPA 1212 P G + G PG PG + F P P + PP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 1213 SRERSS----------SLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGR 1262 + L G A P R + PG ++ GP D G G+ Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ 806 Query: 1263 GGPGPAQRVPKSGRSS-----------SLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGS 1311 GP +P G G H + +P GPPG P G GS Sbjct: 807 PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP--GPPGLDVPGPPGERGS 864 Query: 1312 NWGRGSNMNSGPP 1324 G+ GPP Sbjct: 865 PGIPGAPGPIGPP 877 Score = 180 bits (456), Expect = 9e-45 Identities = 140/365 (38%), Positives = 170/365 (46%), Gaps = 56/365 (15%) Query: 575 PPSSGTPLLGPQP----FPGQGPMSQIPQGFQQPHPSQQMPM---------NMAQMGPPG 621 P GTP QP FPG P P+G P + +P + Q GPPG Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGT-PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 622 PQG---QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQG 676 +G Q PGP GQ G G P G GP G G G +G G+P + GP+G Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223 Query: 677 MQRHPGPHGPLGPQGPPGPQGS-----SGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGP 731 PG HG G QGPPGP GS GP+G+ GPQGPPG G GP+GPPG G+ G Sbjct: 1224 ---EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGI 1280 Query: 732 QGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNP-RGMQGPPGP 790 +G G G G PG G++G P G+QG PG G+ G L G+ GM+GP G Sbjct: 1281 KGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGV 1340 Query: 791 RENQGPAPQGMIMGHP-PQEMRGPH-----------PPG-----GLLG-HGPQEMRGPQE 832 + GP + ++G P P + GP PPG GL G GPQ GPQ Sbjct: 1341 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ---GPQG 1397 Query: 833 IRGMQGPPPQGSMLGPPQ-----ELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQ 887 + G GPP G P +G PG Q G +G GPP G+QGPPGP G Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT-RGLDGPPGPDGLQGPPGPPGTS 1456 Query: 888 NPARG 892 + A G Sbjct: 1457 SVAHG 1461 Score = 173 bits (439), Expect = 9e-43 Identities = 236/779 (30%), Positives = 281/779 (36%), Gaps = 122/779 (15%) Query: 618 GPPGPQGQFRPPGPQGQMG---PQGPPLHQGGGGPQGFMGPQGPQGPPQGLP----RPQD 670 GPPG G PGP G +G +G G GP+G G G G P G P P D Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP-GFPGSKGEPGD 549 Query: 671 MHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHI---GPQGPPGPQG 727 + GM+ G G G G PG G+ G G G GP G G I G +GPPG G Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609 Query: 728 ------HLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGP-------VSQG 774 ++GP GPPG GPPGP G +G G+ G PG GI GP ++Q Sbjct: 610 LPGLPGNIGPMGPPGF----GPPGPVGEKG---IQGVAGNPGQPGIPGPKGDPGQTITQP 662 Query: 775 PLMGL--NPR-----GMQGPPGPRENQG----PAPQGMIMGHPPQEMRGPHPPGGLLG-H 822 GL NP G+ G PG G P +G G P + GP P G G Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE-PGIPGIGLPGPPGPKGFPGIP 721 Query: 823 GPQEMRGPQEIRGMQGPPPQGSMLGPPQE----LRGPPGSQSQQGPPQGSLGPPPQGGMQ 878 GP G G++GPP GP E L GPPG G +G+LGP G Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPG-FKGALGPKGDRGFP 780 Query: 879 GPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEG---QSTGPPPLIPG-L 934 GPPGP G+ P P P Q GP P G Q PP IPG + Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQ-------PGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 935 GQQGAQGRIPPLNPGQ--GPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHG--PERGPF 990 GQ G G PG+ PGP D GPP P G P P + Sbjct: 834 GQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888 Query: 991 RGGQDCRGPPDRRGPHPDFPDDFSRPD-DFHPDKRFGHRLREFEGRGGPLPQE-EKWRRG 1048 G +G GP P P P P + L+ G GP ++ K G Sbjct: 889 SGFPGTKGEMGMMGP-PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG 947 Query: 1049 GPGPPFPPDHREF-SEGD-GRGAARGPPG-----AWEGRRPGDERFPRDPEDPRFRGRRE 1101 PGPP P D S+G+ G G PG ++G PGD P P G Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQG-LPGDPGQPGLSGQPGLPGPPG 1006 Query: 1102 ESFRRGAPPRHEGRAPPR-----GRDGFPGPE--DFGPEENFDASEEAARGRDLRGRGRG 1154 G P + PP G GFPGP+ + P + + + G + +G Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 1155 TPRGGRKGL--LPTPDEFPRFEGGRKPDSWDGNREPG-------PGHEHFRDTPRPDHPP 1205 P GL LP P P G + GN PG PG TP P Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPG------YPGN--PGIKGSVGDPGLPGLPGTPGAKGQP 1118 Query: 1206 HDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGP 1265 L G PP + PG PG P GG G P Sbjct: 1119 -------------GLPGFPGTPGPPGPKGISGPPGNP-----GLPGEPGPVGGGGHPGQP 1160 Query: 1266 GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 GP K G+ G FG P G P G+ G G N G P Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219 Score = 164 bits (414), Expect = 7e-40 Identities = 228/736 (30%), Positives = 281/736 (38%), Gaps = 163/736 (22%) Query: 699 SGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGI 758 SG +G G +G PG +GH G G PGP+G GP+G G G+ GPPGP+G++GPP G Sbjct: 41 SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100 Query: 759 QGGPGSQGIQG----PVSQGPLMGLNPR-------------GMQGPPGPRENQG--PAPQ 799 G PG G+ G P QG + G N G+QGPPGP G P Sbjct: 101 PGTPGLPGMPGHDGAPGPQG-IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPG 159 Query: 800 GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQ 859 +IM P P PG G Q + GP I G GPP ++GPP GPPG Sbjct: 160 SIIMSSLPGPKGNPGYPG---PPGIQGLPGPTGIPGPIGPPGPPGLMGPP----GPPGLP 212 Query: 860 SQQGPP----QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD-GP 914 +G QG G + G+QGPPGP GQ + + P + FQ+ L GD GP Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI----DVEFQKGDQGLPGDRGP 268 Query: 915 RAPFNQEGQSTGPPPLIPG--LGQQGAQG----RIPPLNPGQGPGPNKGDSRGPPNHHMG 968 P G PP PG G++G QG R P G+ P G P + Sbjct: 269 PGPPGIRG-----PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323 Query: 969 PMSERRHEQSG--GPEHGP--------------ERGPF-----------RGGQDCRGPPD 1001 P + Q G GP P E+G RG +GPP Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383 Query: 1002 RRGP----------HPDFPDDFSRPDDFHP-----------DKRFG-HRLREFEGRGGP- 1038 GP P FP + + D P D + G L G GP Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH 443 Query: 1039 -LPQEEKWRRGGPGPPFPPDHREFS-----EGD---------GRGAARGPPGAWEGRRPG 1083 P +E G PGPP P + +GD G G + GPPG +PG Sbjct: 444 IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS-GPPG-----QPG 497 Query: 1084 DERFPRDPEDPRFRGRREESFRRGA--PPRHEGRAPPRGRDGFPG----PEDF--GPEEN 1135 P P F G++ E + GA P G G GFPG P D P Sbjct: 498 LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK 557 Query: 1136 FDASEEAARGRDLRGRGRGTPRGGRKGL--LPTPDEFP---RFEGGRKPDSWDGNREPGP 1190 D E + G GTP G+ GL LP P P F+G R P GN P Sbjct: 558 GDKGELGSPGAPGLPGLPGTP--GQDGLPGLPGPKGEPGGITFKGERGP---PGN----P 608 Query: 1191 GHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAP 1250 G P PP G P +QG +A P +P GP + + P Sbjct: 609 GLPGLPGNIGPMGPP--GFGPPGPVGEKGIQG--VAGNP--GQPGIPGPKGDPGQTITQP 662 Query: 1251 GGPSEDRGGKGRGG----PG----PAQ----RVPKSGRSSSLDGEHHDGYHRDEPF---G 1295 G P G GR G PG P Q +P S + G G + F Sbjct: 663 GKPGLP-GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721 Query: 1296 GPPGS-GTPSRGGRSG 1310 GPPG+ GTP R G G Sbjct: 722 GPPGAPGTPGRIGLEG 737 Score = 130 bits (326), Expect = 1e-29 Identities = 91/244 (37%), Positives = 105/244 (43%), Gaps = 30/244 (12%) Query: 574 PPPSSGTPLLGPQPFPG-QGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQ 632 PP S G L GP+ PG QGP + G P +P N G G GQ PG Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGR--PGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP 1296 Query: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGP 692 G G QGPP QG G G G +G G P G+P M GP G+ GP G G GP Sbjct: 1297 GLKGDQGPPGLQGNPGRPGLNGMKGDPGLP-GVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1355 Query: 693 PGPQGSSGPQGH-------------------------MGPQGPPGPQGHIGPQGPPGPQG 727 PGP G GP G GPQG PGP G G G G G Sbjct: 1356 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1415 Query: 728 HLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGP 787 G G G G+ G PG RG+ GPP P G+QG PG G V+ G L+ + + P Sbjct: 1416 FDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS-VAHGFLITRHSQTTDAP 1474 Query: 788 PGPR 791 P+ Sbjct: 1475 QCPQ 1478 Score = 53.5 bits (127), Expect = 1e-06 Identities = 127/498 (25%), Positives = 160/498 (32%), Gaps = 94/498 (18%) Query: 844 SMLGPPQELRG----PPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP 899 S+ G P E PGS+ +G G G++G PG G P Sbjct: 18 SLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGP---------- 67 Query: 900 IPFQQQKTPLLGDGPRAPFNQEGQS--TGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKG 957 +GP P Q+G GPP G +G +G PP PG P Sbjct: 68 ------------EGPPGPRGQKGDDGIPGPP------GPKGIRG--PPGLPG---FPGTP 104 Query: 958 DSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPD 1017 G P H P GP+ G C G RG FP P Sbjct: 105 GLPGMPGHDGAP----------GPQ---------GIPGCNGTKGERG----FPGSPGFPG 141 Query: 1018 DFHPDKRFGHRLREFEGRGGPLPQEE-KWRRGGPGPPFPPDHREFSEGDGRGAARGPPGA 1076 P G + +G G + +G PG P PP + G GPPG Sbjct: 142 LQGPPGPPG--IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 1077 WEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENF 1136 PG P P P +G +F+ P +G +G G PGP E+ Sbjct: 200 -----PGLMGPPGPPGLPGPKGNMGLNFQ--GPKGEKGE---QGLQGPPGPPGQISEQKR 249 Query: 1137 DASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFR 1196 E +G RG P G G+ P P E G K + + + PG + Sbjct: 250 PIDVEFQKGDQGLPGDRGPP--GPPGIRGPPGP-PGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 1197 DTPRPDHPPHDGHSPA--SRERSSSLQGMDMASLPPRKRPWHDGPGTS--EHREMEAPGG 1252 P P D P R+ +G PP G G + E + PG Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 1253 PSE--DRGGKG-RGGPG----PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSR 1305 P E +RG G +G PG P V GE G DE GPPG P Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER--GQKGDE---GPPGISIPGP 421 Query: 1306 GGRSGSNWGRGSNMNSGP 1323 G G G GP Sbjct: 422 PGLDGQPGAPGLPGPPGP 439 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 219 bits (557), Expect = 2e-56 Identities = 268/872 (30%), Positives = 327/872 (37%), Gaps = 179/872 (20%) Query: 584 GPQPFPGQ-GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPL 642 GP FPG GP +I N GP GP+G+ PG G +GP G P Sbjct: 253 GPPGFPGAPGPKGEIGA-----------VGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPG 301 Query: 643 HQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQ 702 G G +G G G G P GLP P+ + GP G G G +G GP G +G SG + Sbjct: 302 ANGLTGAKGAAGLPGVAGAP-GLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNK 360 Query: 703 GHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGP 762 G G GP GP G G +G GP G G GPPG G++G PG RG+ G G+ G P Sbjct: 361 GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420 Query: 763 GSQGIQGPVS-QGP-----------LMGLNPRGMQGPP---GPRENQGPAPQGMIMGHP- 806 GS+G GP +GP LMG PRG+ G P GP +GP I G P Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGEPGLMG--PRGLPGSPGNIGPAGKEGPVGLPGIDGRPG 478 Query: 807 ---PQEMRG-------PHPPG--------GLLGH----GPQEMRGPQEIRGMQGPP-PQG 843 P RG P P G G GH G + GP G QGPP PQG Sbjct: 479 PIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQG 538 Query: 844 -----SMLGPPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQ------GPPGPQGQQNPA 890 GPP GPPG Q GP P G +G P + G+ GP GP+G++ P Sbjct: 539 VQGGKGEQGPP----GPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPP 594 Query: 891 RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ-------STGPPPLIPGL-GQQGAQGR 942 G + GP + P GP P +G+ T P GL G++GA G Sbjct: 595 -GESGAAGPTGPIGSRGP---SGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAG- 649 Query: 943 IP--------PLNPGQGPGPNKGDSRGPPN-----HHMGPMSERRHEQSGGPEHGPERGP 989 IP P G+ P + +RG P G +R + GP GP GP Sbjct: 650 IPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPA-GP-AGP 707 Query: 990 FRGGQDCRGPPDRRGP-HPDFPDDFSRPDDF--HPDKRFGHRLREFEGRGGPLPQEEKWR 1046 RG P RG P P+ F+ P P + + +G G + Sbjct: 708 -------RGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVG 760 Query: 1047 RGGPGPPFPPDHREFSEGDGRGAARGPPG-------AWEGRRPGDERFPRDPEDPRFRGR 1099 GP P P S GDG GPPG A PG P P G+ Sbjct: 761 AAGPAGPNGPPGPAGSRGDG-----GPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGK 815 Query: 1100 REESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGG 1159 E R P +G G G GP F A E+ G GTP G Sbjct: 816 --EGLR--GPRGDQGPVGRTGEVGAVGPPGF-------AGEKGPSGEAGTAGPPGTP--G 862 Query: 1160 RKGLLPTPD--EFPRFEGGR-KPDSWDGNREPGP----GHEHFRDTP------------- 1199 +GLL P P G R P EPGP G R P Sbjct: 863 PQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPG 922 Query: 1200 ---RPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGP-GTSEHREMEAPGGPSE 1255 R +P +DG P R+ +G R P + GP G + P GP+ Sbjct: 923 EAGRDGNPGNDG--PPGRDGQPGHKG-------ERGYPGNIGPVGAAGAPGPHGPVGPAG 973 Query: 1256 DRGGKGRGGP----GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG-------SGTPS 1304 G +G GP GPA V G S G ++ G PG G P Sbjct: 974 KHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPG 1033 Query: 1305 RGGRSGSNWGRGSNMNSGPPRRGASRGGGRGR 1336 G G GS +G PR A G G+ Sbjct: 1034 IAGHHGDQGAPGSVGPAG-PRGPAGPSGPAGK 1064 Score = 216 bits (549), Expect = 2e-55 Identities = 250/826 (30%), Positives = 303/826 (36%), Gaps = 124/826 (15%) Query: 598 PQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGG-------GPQ 650 P G + P + P + G GP G PPGP G G G Q G GP Sbjct: 34 PAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPM 93 Query: 651 GFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGP 710 G MGP+GP G G P PQ GP G PG GP G +GP GP G +G GH G G Sbjct: 94 GLMGPRGPPG-AAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGR 152 Query: 711 PGPQGHIGPQ------GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGS 764 PG +G +GPQ G PG G G +G G G++G PG G++G P G G PG Sbjct: 153 PGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQ 212 Query: 765 QGIQG-PVSQGPLMGLNPRGMQGPPGPRENQGPA-PQGMIMGHPPQEMRGPHPPGGLLGH 822 G +G P +G + P G +G G GPA P G PP P P G + Sbjct: 213 TGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIG--SAGPPGFPGAPGPKGEIGAV 270 Query: 823 GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPG 882 G GP RG G P +GPP G PG+ G +G+ G P G G PG Sbjct: 271 GNAGPAGPAGPRGEVGLPGLSGPVGPP----GNPGANGLTG-AKGAAGLPGVAGAPGLPG 325 Query: 883 PQGQQNPA--------------RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ----- 923 P+G P GP S+G + + GP P +EG+ Sbjct: 326 PRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNG 385 Query: 924 --STGPPPLIPGL-------GQQGAQGRIPPLNP-----GQGP----GPNKGDSRGPPNH 965 + PP PGL G GA GR + P GP GPN R Sbjct: 386 EAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPG 445 Query: 966 HMGPMSERRHEQSGGP--EHGP--------ERGPFRGGQDCRGPPDRRG-PHPDFP--DD 1012 MGP + GP + GP GP G RG P G P P P D Sbjct: 446 LMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPI-GPAGARGEPGNIGFPGPKGPTGDP 504 Query: 1013 FSRPDDFHPDKRFGHRLREFEGRGG----PLPQEEKWRRGGPGPPFPPDHREFSEGDGRG 1068 D H +G G P PQ + +G GPP PP + G Sbjct: 505 GKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPA 564 Query: 1069 AARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPE 1128 G PG E G+ P P P RG R PP G A P G G GP Sbjct: 565 GEVGKPG--ERGLHGEFGLP-GPAGP--RGER-------GPPGESGAAGPTGPIGSRGPS 612 Query: 1129 -DFGPEENFDASEEAARGRDLRGRGRGTPRG--GRKGLLPTPDEFPRFEGGRKPDSWDGN 1185 GP+ N E G + G P G G +G P GG+ G Sbjct: 613 GPPGPDGN--KGEPGVVGA-VGTAGPSGPSGLPGERGAAGIP-------GGKGEKGEPGL 662 Query: 1186 REP--GPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGP-GTS 1242 R PG + R P P G + A+ +R + PR P G G + Sbjct: 663 RGEIGNPGRDGARGAPGAVGAP--GPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPA 720 Query: 1243 EHREMEAPGGPSEDRGGKGRGGP----------GPAQRVPKSGRSSSLDGEHHDGYHRDE 1292 P G + G KG G GP V +G + G D Sbjct: 721 GPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGD- 779 Query: 1293 PFGGPPG-SGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG--GGRG 1335 GGPPG +G P GR+G G + GPP G G RG Sbjct: 780 --GGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRG 823 Score = 215 bits (547), Expect = 3e-55 Identities = 227/739 (30%), Positives = 274/739 (37%), Gaps = 115/739 (15%) Query: 610 MPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQ 669 +P + +GP G +G PG G+ GP GP +G G GF GP+GP G P G + Sbjct: 452 LPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDP-GKNGDK 510 Query: 670 DMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGP------- 722 G G + PGP G G QGPPGPQG G +G GP GPPG QG GP GP Sbjct: 511 GHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKP 570 Query: 723 -----------PGPQGHLGPQGPPGTQGMQGPPGP---RGMQGPPHPHGIQGGPGSQGIQ 768 PGP G G +GPPG G GP GP RG GPP P G +G PG G Sbjct: 571 GERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAV 630 Query: 769 GPVSQGPLMGL-NPRGMQGPPGPRENQG-PAPQGMIMGHP--------PQEMRGPHPPGG 818 G GL RG G PG + +G P +G I G+P P + P P G Sbjct: 631 GTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEI-GNPGRDGARGAPGAVGAPGPAGA 689 Query: 819 LLGHGPQEMRGPQEIRGMQGPPPQGSMLGP--PQELRGPPGSQSQQGPP--QGSLGPPPQ 874 G GP G +G P + +GP P GP G+ Q G +G+ GP + Sbjct: 690 TGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGE 749 Query: 875 GGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGL 934 G+ GP GP G PA GP+ GP + GDG GPP + Sbjct: 750 NGVVGPTGPVGAAGPA-GPNGPPGPAGSR-------GDG------------GPPGMT--- 786 Query: 935 GQQGAQGRIPPLNPGQ------GPGPNKGDSRGPPNHHMGPMSERRHEQSGGPE-HGPER 987 G GA GR P P PGP + P GP+ + GP E+ Sbjct: 787 GFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEK 846 Query: 988 GPFRGGQDCRGPPDRRGPHP--DFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKW 1045 GP G GPP GP P P R G G + Sbjct: 847 GP-SGEAGTAGPPGTPGPQGLLGAPGILGLPGS--------RGERGLPGVAGAV------ 891 Query: 1046 RRGGPGP---PFPPDHREFSEGDGRGAARGPPG-AWEGRRPGDERFPRDPEDPRFRGRRE 1101 G PGP PP R G G PG A PG++ P P +G R Sbjct: 892 --GEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGER- 948 Query: 1102 ESFRRGAPPRHEGRAPPRGRDGFPGPED-FGPEENFDASEEAARGRDLRGRGRGTPRG-- 1158 G P G P G G PGP GP E + G PRG Sbjct: 949 -----GYP----GNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPS 999 Query: 1159 GRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSS 1218 G +G+ E G + P G + GH + P D +P S + Sbjct: 1000 GPQGIRGDKGE----PGEKGPRGLPGLK----GHNGLQGLPGIAGHHGDQGAPGSVGPAG 1051 Query: 1219 SLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSS 1278 +G S P K PGT + P G G G GP V G Sbjct: 1052 P-RGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDF 1110 Query: 1279 SLDGEHHDGYHRDEPFGGP 1297 DG D Y D+P P Sbjct: 1111 GYDG---DFYRADQPRSAP 1126 Score = 211 bits (538), Expect = 3e-54 Identities = 212/674 (31%), Positives = 262/674 (38%), Gaps = 120/674 (17%) Query: 572 IQPPPSSGTPLLGPQPFPG-QGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPG 630 I P + G P G FPG +GP + + H G PGP G G Sbjct: 480 IGPAGARGEP--GNIGFPGPKGPTGDPGKNGDKGHAGLA-----GARGAPGPDGNNGAQG 532 Query: 631 PQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQ--GLPRPQDMHGPQGMQRHPGPHGPLG 688 P G G QG QG GP GF G GP GP G P + +HG G+ PGP GP G Sbjct: 533 PPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGL---PGPAGPRG 589 Query: 689 PQGPPGPQGSSGPQGHMG---PQGPPGPQGH------------IGPQGPPGPQGHLGPQG 733 +GPPG G++GP G +G P GPPGP G+ GP GP G G G G Sbjct: 590 ERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAG 649 Query: 734 PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPREN 793 PG +G +G PG RG G P G +G PG+ G GP G G GP GP Sbjct: 650 IPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA--GATGDRGEAGAAGPAGPAGP 707 Query: 794 QG-PAPQGMIMGHPPQEMRGPHPPGGLLG-HGPQEMRGPQEIRGMQGPPPQGSMLGP--P 849 +G P +G + P GP G G G + +GP+ G+ GP GP P Sbjct: 708 RGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGP 767 Query: 850 QELRGPPGSQSQQGPP--------QGSLGPPPQGGMQGPPGPQGQ--QNPARGPHPSQGP 899 GP GS+ GPP G GPP G+ GPPGP G + RGP QGP Sbjct: 768 NGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGP 827 Query: 900 IPFQQQKTPLLGD-GPRAPFNQEGQS----TGPPPLIPG----------LGQQGAQGR-- 942 + +T +G GP ++G S T PP PG LG G++G Sbjct: 828 VG----RTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERG 883 Query: 943 IPPLNPGQG-PGPNKGDSRGPPNHHMGPMSERRHEQSGGP-EHGPERGPFRGGQDCRGPP 1000 +P + G PGP GPP P + +G P E G + P G D GPP Sbjct: 884 LPGVAGAVGEPGPL--GIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNP---GND--GPP 936 Query: 1001 DRRGPHPDFPDDFSRPDDFHPDKRFG-------------HRLREFEGRGGPL-------- 1039 R G P + P + P G H R G GP+ Sbjct: 937 GRDG-QPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGP 995 Query: 1040 -----PQEEKWRRGGPGPPFP------PDHREFSEGDGRGAARGPPGAWEGRRPGDERFP 1088 PQ + +G PG P H G G GA P R P Sbjct: 996 RGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGP 1055 Query: 1089 RDPEDPRFR-GRREESFRRG-----APPRHEGRAPPRGRDGFPGPE-------DFGPEEN 1135 P P + GR G P H+G A P G G PGP DFG + + Sbjct: 1056 AGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGD 1115 Query: 1136 FDASEEAARGRDLR 1149 F +++ LR Sbjct: 1116 FYRADQPRSAPSLR 1129 Score = 43.1 bits (100), Expect = 0.002 Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 2/62 (3%) Query: 611 PMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLP--RP 668 P + G GPQG P GP G GP GPP GGG G+ G P+ P RP Sbjct: 1071 PGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRP 1130 Query: 669 QD 670 +D Sbjct: 1131 KD 1132 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 218 bits (556), Expect = 2e-56 Identities = 253/801 (31%), Positives = 303/801 (37%), Gaps = 124/801 (15%) Query: 574 PPPSSGTP----LLGPQPFPG-QGPMSQIPQGFQQPHPSQQ--MPMNMAQMGPPGPQGQF 626 PP + GTP L GP PG GP + GF P P +P +GP G +G Sbjct: 723 PPGAPGTPGRIGLEGPPGPPGFPGPKGE--PGFALPGPPGPPGLPGFKGALGPKGDRGFP 780 Query: 627 RPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP----QGLPRPQDMHGPQGMQRHPG 682 PPGP G+ G G P +G GP G GP GP G P QG P P + GP G PG Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ---PG 837 Query: 683 PHGPLGPQGPPGPQGSS--GPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG- 739 HG G +G PGP G GP G G G PG G IGP G PG G G G PGT+G Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 897 Query: 740 --MQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-PVSQGPLMGLNPRGMQGPPGPRENQGP 796 M GPPGP G G P G+ G G G+QG P GP +G G PGP P Sbjct: 898 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP-----P 952 Query: 797 APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPP 856 P + E P PG + GP+ +G+ G P Q + G P L GPP Sbjct: 953 GPMDPNLLGSKGEKGEPGLPG------IPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPP 1005 Query: 857 GSQSQQGPP--QGSLGPPPQGGMQGP---PGPQGQQNPARGPHPSQGPIPFQQQKTPLLG 911 G + G P G +GPP G G PGPQG + P P +P Q L G Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP-----PGPSGVPGQPGSPGLPG 1060 Query: 912 DGPRAPFNQEGQSTGPPPLIPGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPM 970 Q+G P GL G G +G P PG P S G P P Sbjct: 1061 --------QKGDKGDPGISSIGLPGLPGPKGE--PGLPGYPGNPGIKGSVGDPGLPGLPG 1110 Query: 971 SERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLR 1030 + Q G P GP G + GPP G P + P GH Sbjct: 1111 TPGAKGQPGLPGFPGTPGP-PGPKGISGPPGNPG----------LPGEPGPVGGGGHP-- 1157 Query: 1031 EFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPG--AWEGRRPGDERFP 1088 G P P EK + G G P P + G G GPPG G++ GD P Sbjct: 1158 -----GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLSGQK-GDGGLP 1210 Query: 1089 RDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDL 1148 P +P G + E G P G P G G PGP GP+ N R Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFP----GVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPT 1266 Query: 1149 RGRGRGTPRG--------GRKGLLPTPDE-----FPRFEGGRKPDSWDGNREPG-PGHEH 1194 +G P G G KG P + P +G + P GN PG PG Sbjct: 1267 GFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN--PGRPGLNG 1324 Query: 1195 FRDTPR-PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSE---HREMEAP 1250 + P P P G S S+ + + P P GP + P Sbjct: 1325 MKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPP 1384 Query: 1251 GGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSG 1310 G P + G KG GP Q +P GPPG P R G G Sbjct: 1385 GIPGQP-GLKGLPGPQGPQGLPGPT--------------------GPPGD--PGRNGLPG 1421 Query: 1311 SNWGRGSNMNSGPPRRGASRG 1331 + G + G P + +RG Sbjct: 1422 FDGAGGRKGDPGLPGQPGTRG 1442 Score = 209 bits (532), Expect = 1e-53 Identities = 246/791 (31%), Positives = 303/791 (38%), Gaps = 114/791 (14%) Query: 616 QMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQG--PPQGLPRPQDMHG 673 + G PG +G PG G GP+GPP +G G G GP GP+G P GLP Sbjct: 49 ERGFPGLEGH---PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP------- 98 Query: 674 PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQG 733 G PG G G G PGPQG G G G +G PG G G QGPPGP G G +G Sbjct: 99 --GFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 734 PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVS-QGPLMGLNPRGMQGPPGPRE 792 PG+ M PGP+G G P P GIQG PG GI GP+ GP + P G G PGP+ Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 793 NQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEM-----RGPQEIRGMQGPPPQGSMLG 847 N G QG Q ++GP P G + + + +G Q + G +GPP + G Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 848 PPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG-QQNPARGPHPSQGPIPFQQQK 906 PP G G + +QG P G G P + G G PG G +P P + Q+ Sbjct: 277 PPGPPGGEKGEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335 Query: 907 T-PLLGDGPRAPFNQEGQSTGPPPLI--PGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGP 962 T P G P G + G I PGL G++G +G P PGP GP Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395 Query: 963 PNHHMGPMSERRHEQSGGPEHGPERGP-----FRGGQDCRGPPDRRGPHPDFPDDFSRPD 1017 P P ER + GP GP G GPP GPH D+ P Sbjct: 396 PGPPGFP-GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454 Query: 1018 DFHPDKRFGHRLREFE---------------GRGGPLPQEEKWRRGGPGPP----FPPDH 1058 P G + + E G G P + G PGPP FP Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514 Query: 1059 REFSEGDGRG--AARGPPGAWEGRRPGDERFP---RDPED----PRFRGRREESFRRGAP 1109 E + G G PGA PG FP +P D P +G + E GAP Sbjct: 515 GEKGQAGATGPKGLPGIPGA-----PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 1110 --PRHEGRAPPRGRDGFPGPE----------DFGPEENFDASEEAARGRDLRGRGRGTP- 1156 P G G G PGP+ + GP N + G G P Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 1157 ---RGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPG-------PGHEHFRDTPRPDHPPH 1206 G +G+ P + P G K D +PG PG + D P P Sbjct: 630 PVGEKGIQGVAGNPGQ-PGIP-GPKGDPGQTITQPGKPGLPGNPGRD--GDVGLPGDPGL 685 Query: 1207 DGHS-----PASRERSSSLQGMDMASLP-PRKRPWHDG----PGTSEHREMEAPGGPSED 1256 G P S+ + G+ + P P+ P G PGT +E P GP Sbjct: 686 PGQPGLPGIPGSK-GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744 Query: 1257 RGGKGRGG---PGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNW 1313 G KG G PGP G +L G D F GPP G P R G G Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGAL------GPKGDRGFPGPP--GPPGRTGLDGLPG 796 Query: 1314 GRGSNMNSGPP 1324 +G +G P Sbjct: 797 PKGDVGPNGQP 807 Score = 207 bits (527), Expect = 5e-53 Identities = 211/663 (31%), Positives = 253/663 (38%), Gaps = 104/663 (15%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP-- 631 PP G+P + P P P S G M MGPPGP G PG Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917 Query: 632 ----------QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHP 681 QGQ G GP +G G G GP GP P L + G G+ P Sbjct: 918 VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP--NLLGSKGEKGEPGLPGIP 975 Query: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQ 741 G GP G QG PG G G G G GPPGP+G+ G PG G +GP G GT G Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN---PGLPGQPGLIGPPGLKGTIGDM 1032 Query: 742 GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGM 801 G PGP+G++GPP P G+ G PGS G+ G G++ G+ G PGP+ G Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPG------ 1086 Query: 802 IMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQ 861 + G+P PG G + G G +G P G P GPPG Sbjct: 1087 LPGYPGN-------PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP----GPPG---- 1131 Query: 862 QGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQE 921 P+G GPP G+ G PGP G G HP Q P ++ K DG P Q+ Sbjct: 1132 ---PKGISGPPGNPGLPGEPGPVG-----GGGHPGQPGPPGEKGKPG--QDGIPGPAGQK 1181 Query: 922 GQSTGP------PPLIPGLGQQGAQGRIP--PLNPGQGPGPNKGDSRGPPNHHMGPMSER 973 G+ P PP +PGL Q G +P P NPG PGP +G P H P + Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL-PGP-----KGEPGFHGFPGVQG 1235 Query: 974 RHEQSGGPEHGPERGPFRGGQDCRGPPDRRGP--HPDFPDDFSRPDDFHPDKRFGHRLRE 1031 G P GP +G +GPP R GP P P Sbjct: 1236 PPGPPGSP--GPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPG-------------- 1279 Query: 1032 FEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRD- 1090 G GG K +G PG P P G +G PG RPG D Sbjct: 1280 LPGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG-----RPGLNGMKGDP 1329 Query: 1091 --PEDPRFRGRREESFRRGA--PPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGR 1146 P P F G + S G+ P G P G G PGP DA G+ Sbjct: 1330 GLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ 1389 Query: 1147 -DLRG-RGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWD--GNREPGPGHEHFRDTPRPD 1202 L+G G P+G LP P P G +D G R+ PG T D Sbjct: 1390 PGLKGLPGPQGPQG-----LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLD 1444 Query: 1203 HPP 1205 PP Sbjct: 1445 GPP 1447 Score = 194 bits (492), Expect = 6e-49 Identities = 253/853 (29%), Positives = 306/853 (35%), Gaps = 205/853 (24%) Query: 618 GPPGPQGQFRPPG------PQGQMGPQGPPLHQGGGGPQ------------------GFM 653 GPPGP+G PPG G G G H G GPQ GF Sbjct: 84 GPPGPKGIRGPPGLPGFPGTPGLPGMPG---HDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 654 GPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGP 713 G QGP GPP G+P + G M PGP G G GPPG QG GP G GP GPPGP Sbjct: 141 GLQGPPGPP-GIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 714 QGHIGPQGP---PGPQGHL-----GPQGPPGTQGMQGPPGP----------------RGM 749 G +GP GP PGP+G++ GP+G G QG+QGPPGP +G Sbjct: 200 PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGD 259 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMG-LNPRGMQGPPGPR-------ENQGPAPQGM 801 QG P G +G PG GI+GP GP G +G QG PG R EN P G+ Sbjct: 260 QGLP---GDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314 Query: 802 --IMGHPPQEMR----------GPHPPGGLL----GHG--------------PQEMRGPQ 831 G+P + R GP P GL+ G G P E +G + Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGER 373 Query: 832 EIRGMQGP-----PPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQ 886 G+QGP PP +++GPP GPPG ++G +G GPP + GPPG GQ Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPP----GPPGFPGERG-QKGDEGPPGI-SIPGPPGLDGQ 427 Query: 887 QNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPL 946 P P GP GP P + E GPP G +G QG Sbjct: 428 PGAPGLPGP-PGPA------------GPHIPPSDEICEPGPPGPPGSPGDKGLQGE---- 470 Query: 947 NPGQGPGPNKGDS---------RGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCR 997 QG +KGD+ GPP P G P E+G G + Sbjct: 471 ---QGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ-AGATGPK 526 Query: 998 GPPDRRGP--HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFP 1055 G P G P FP P D + F G G +K G PG P Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGD----------ILTFPGMKG-----DKGELGSPGAPGL 571 Query: 1056 PDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAP------ 1109 P DG GP G G ER P P +P G G P Sbjct: 572 PGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP--PGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 1110 ----PRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLP 1165 +G A G+ G PGP+ + + G R G P G G LP Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP--GDPG-LP 686 Query: 1166 TPDEFPRFEGGRKPDSWDGNREPG-PGHEHFRDTPRP------------DHPPHDGHSPA 1212 P G + G PG PG + F P P + PP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 1213 SRERSS----------SLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGR 1262 + L G A P R + PG ++ GP D G G+ Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ 806 Query: 1263 GGPGPAQRVPKSGRSS-----------SLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGS 1311 GP +P G G H + +P GPPG P G GS Sbjct: 807 PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP--GPPGLDVPGPPGERGS 864 Query: 1312 NWGRGSNMNSGPP 1324 G+ GPP Sbjct: 865 PGIPGAPGPIGPP 877 Score = 190 bits (483), Expect = 7e-48 Identities = 245/811 (30%), Positives = 310/811 (38%), Gaps = 154/811 (18%) Query: 575 PPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 P G P L GP+ PG +G + P + +P +GP GP G F PPGP G Sbjct: 578 PGQDGLPGLPGPKGEPGGITF----KGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVG 632 Query: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPP 693 + G QG G G G GP+G G Q + +P G G+ +PG G +G G P Sbjct: 633 EKGIQGVA---GNPGQPGIPGPKGDPG--QTITQP----GKPGLPGNPGRDGDVGLPGDP 683 Query: 694 GPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG------MQGPPGPR 747 G G G G G +G PG G IG GPPGP+G G GPPG G ++GPPGP Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742 Query: 748 GMQGPPHPHG--IQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG----PAPQGM 801 G GP G + G PG G+ G +G L RG GPPGP G P P+G Sbjct: 743 GFPGPKGEPGFALPGPPGPPGLPG--FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGD 800 Query: 802 IMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP--------------PQGSMLG 847 + P GP P GL G G Q GP I G G P P + G Sbjct: 801 V---GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG 857 Query: 848 PPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP--IPFQ 903 PP E RG PG GP P GS G P + G G PG +G+ GP GP IP + Sbjct: 858 PPGE-RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG-MMGPPGPPGPLGIPGR 915 Query: 904 QQKTPLLGD----------GPRAPFNQEGQS--TGPP-PLIPGL-GQQGAQGRIPPLNPG 949 L GD GP +G+ GPP P+ P L G +G +G P PG Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE--PGLPG 973 Query: 950 QGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP----EHGPERGPFRGGQD-CRGPPDRRG 1004 PG + GP + P + SG P GP+ P GQ GPP +G Sbjct: 974 I-PGVS-----GPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKG 1027 Query: 1005 PHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEG 1064 D F P G P P + G PG P ++ +G Sbjct: 1028 TIGDM--GFPGPQGVE---------------GPPGPSGVPGQPGSPGLP----GQKGDKG 1066 Query: 1065 DGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGF 1124 D ++ G PG + G+ P P +P +G + G P + P G GF Sbjct: 1067 DPGISSIGLPGLPGPK--GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP-GLPGF 1123 Query: 1125 PG-PEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWD 1183 PG P GP+ L G GG G P E + + G+ Sbjct: 1124 PGTPGPPGPK----GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE--KGKPGQDGIPGP 1177 Query: 1184 GNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMD-MASLP-PRKRP-WHDGPG 1240 ++ PG F + P P G ++ L G+ LP P+ P +H PG Sbjct: 1178 AGQKGEPGQPGFGNPGPPGLPGLSG-----QKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232 Query: 1241 TSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS 1300 ++ P GP G PGPA PK G P Sbjct: 1233 ------VQGPPGPP--------GSPGPALEGPK---------------------GNPGPQ 1257 Query: 1301 GTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 G P R G +G G G P G +G Sbjct: 1258 GPPGRPGPTGFQGLPGPEGPPGLPGNGGIKG 1288 Score = 190 bits (483), Expect = 7e-48 Identities = 183/553 (33%), Positives = 222/553 (40%), Gaps = 97/553 (17%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 PP LLG + G+ + IP G P Q +P + Q G G G PPGP+G Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIP-GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009 Query: 634 ------QMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----------QGLPRPQDMHGPQG 676 Q G GPP +G G GF GPQG +GPP GLP + G G Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069 Query: 677 MQRH--PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP 734 + PG GP G G PG G+ G +G +G G PG G G +G PG G G GP Sbjct: 1070 ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP 1129 Query: 735 PGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGL-NPRGMQGPPGPREN 793 PG +G+ GPPG G+ G P P G G PG G G + G+ P G +G PG Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 794 QGPAPQGMIMGHPPQEMRGPHP--PGGLLGHGPQEMRGPQEIRGMQGPP-PQGSMLGPPQ 850 P P G+ G Q+ G P PG GP+ G G+QGPP P GS P Sbjct: 1190 GNPGPPGL-PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS---PGP 1245 Query: 851 ELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG----------QQNPARGPHPSQGPI 900 L GP G+ QGPP G GP G+ GP GP G + NP + P + Sbjct: 1246 ALEGPKGNPGPQGPP-GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1304 Query: 901 PFQQQKTPLLGDGPRAPFNQEGQSTGPP--PLIPGL----------GQQGAQGRIPPLNP 948 Q L G+ R N G P P PG+ G +G G I P P Sbjct: 1305 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1364 Query: 949 GQGPGPN------KGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDR 1002 PGP+ KGD+ GPP G P G Q +G P Sbjct: 1365 PGLPGPSGQSIIIKGDA-GPP----------------GIPGQPGLKGLPGPQGPQGLPGP 1407 Query: 1003 RGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFS 1062 GP P D R + L F+G GG R+G PG P P R Sbjct: 1408 TGP----PGDPGR-----------NGLPGFDGAGG--------RKGDPGLPGQPGTRGLD 1444 Query: 1063 EGDGRGAARGPPG 1075 G +GPPG Sbjct: 1445 GPPGPDGLQGPPG 1457 Score = 176 bits (445), Expect = 2e-43 Identities = 143/374 (38%), Positives = 172/374 (45%), Gaps = 68/374 (18%) Query: 575 PPSSGTPLLGPQP----FPGQGPMSQIPQGFQQPHPSQQMPM---------NMAQMGPPG 621 P GTP QP FPG P P+G P + +P + Q GPPG Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGT-PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 622 PQG---QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQG 676 +G Q PGP GQ G G P G GP G G G +G G+P + GP+G Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223 Query: 677 MQRHPGPHGPLGPQGPPGPQGS-----SGPQGHMGPQGPPGPQGHIGPQGPPGPQGH--- 728 PG HG G QGPPGP GS GP+G+ GPQGPPG G G QG PGP+G Sbjct: 1224 ---EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGL 1280 Query: 729 ------LGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNP- 781 G +G PG G+ G PG +G QGPP G+QG PG G+ G L G+ Sbjct: 1281 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP---GLQGNPGRPGLNGMKGDPGLPGVPGF 1337 Query: 782 RGMQGPPGPRENQGPAPQGMIMGHP-PQEMRGPH-----------PPG-----GLLG-HG 823 GM+GP G + GP + ++G P P + GP PPG GL G G Sbjct: 1338 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1397 Query: 824 PQEMRGPQEIRGMQGPPPQGSMLGPPQ-----ELRGPPGSQSQQGPPQGSLGPPPQGGMQ 878 PQ GPQ + G GPP G P +G PG Q G +G GPP G+Q Sbjct: 1398 PQ---GPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT-RGLDGPPGPDGLQ 1453 Query: 879 GPPGPQGQQNPARG 892 GPPGP G + A G Sbjct: 1454 GPPGPPGTSSVAHG 1467 Score = 173 bits (439), Expect = 9e-43 Identities = 236/779 (30%), Positives = 281/779 (36%), Gaps = 122/779 (15%) Query: 618 GPPGPQGQFRPPGPQGQMG---PQGPPLHQGGGGPQGFMGPQGPQGPPQGLP----RPQD 670 GPPG G PGP G +G +G G GP+G G G G P G P P D Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP-GFPGSKGEPGD 549 Query: 671 MHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHI---GPQGPPGPQG 727 + GM+ G G G G PG G+ G G G GP G G I G +GPPG G Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609 Query: 728 ------HLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGP-------VSQG 774 ++GP GPPG GPPGP G +G G+ G PG GI GP ++Q Sbjct: 610 LPGLPGNIGPMGPPGF----GPPGPVGEKG---IQGVAGNPGQPGIPGPKGDPGQTITQP 662 Query: 775 PLMGL--NPR-----GMQGPPGPRENQG----PAPQGMIMGHPPQEMRGPHPPGGLLG-H 822 GL NP G+ G PG G P +G G P + GP P G G Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE-PGIPGIGLPGPPGPKGFPGIP 721 Query: 823 GPQEMRGPQEIRGMQGPPPQGSMLGPPQE----LRGPPGSQSQQGPPQGSLGPPPQGGMQ 878 GP G G++GPP GP E L GPPG G +G+LGP G Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPG-FKGALGPKGDRGFP 780 Query: 879 GPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEG---QSTGPPPLIPG-L 934 GPPGP G+ P P P Q GP P G Q PP IPG + Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQ-------PGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 935 GQQGAQGRIPPLNPGQ--GPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHG--PERGPF 990 GQ G G PG+ PGP D GPP P G P P + Sbjct: 834 GQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888 Query: 991 RGGQDCRGPPDRRGPHPDFPDDFSRPD-DFHPDKRFGHRLREFEGRGGPLPQE-EKWRRG 1048 G +G GP P P P P + L+ G GP ++ K G Sbjct: 889 SGFPGTKGEMGMMGP-PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG 947 Query: 1049 GPGPPFPPDHREF-SEGD-GRGAARGPPG-----AWEGRRPGDERFPRDPEDPRFRGRRE 1101 PGPP P D S+G+ G G PG ++G PGD P P G Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQG-LPGDPGQPGLSGQPGLPGPPG 1006 Query: 1102 ESFRRGAPPRHEGRAPPR-----GRDGFPGPE--DFGPEENFDASEEAARGRDLRGRGRG 1154 G P + PP G GFPGP+ + P + + + G + +G Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 1155 TPRGGRKGL--LPTPDEFPRFEGGRKPDSWDGNREPG-------PGHEHFRDTPRPDHPP 1205 P GL LP P P G + GN PG PG TP P Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPG------YPGN--PGIKGSVGDPGLPGLPGTPGAKGQP 1118 Query: 1206 HDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGP 1265 L G PP + PG PG P GG G P Sbjct: 1119 -------------GLPGFPGTPGPPGPKGISGPPGNP-----GLPGEPGPVGGGGHPGQP 1160 Query: 1266 GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 GP K G+ G FG P G P G+ G G N G P Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219 Score = 164 bits (414), Expect = 7e-40 Identities = 228/736 (30%), Positives = 281/736 (38%), Gaps = 163/736 (22%) Query: 699 SGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGI 758 SG +G G +G PG +GH G G PGP+G GP+G G G+ GPPGP+G++GPP G Sbjct: 41 SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100 Query: 759 QGGPGSQGIQG----PVSQGPLMGLNPR-------------GMQGPPGPRENQG--PAPQ 799 G PG G+ G P QG + G N G+QGPPGP G P Sbjct: 101 PGTPGLPGMPGHDGAPGPQG-IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPG 159 Query: 800 GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQ 859 +IM P P PG G Q + GP I G GPP ++GPP GPPG Sbjct: 160 SIIMSSLPGPKGNPGYPG---PPGIQGLPGPTGIPGPIGPPGPPGLMGPP----GPPGLP 212 Query: 860 SQQGPP----QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD-GP 914 +G QG G + G+QGPPGP GQ + + P + FQ+ L GD GP Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI----DVEFQKGDQGLPGDRGP 268 Query: 915 RAPFNQEGQSTGPPPLIPG--LGQQGAQG----RIPPLNPGQGPGPNKGDSRGPPNHHMG 968 P G PP PG G++G QG R P G+ P G P + Sbjct: 269 PGPPGIRG-----PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323 Query: 969 PMSERRHEQSG--GPEHGP--------------ERGPF-----------RGGQDCRGPPD 1001 P + Q G GP P E+G RG +GPP Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383 Query: 1002 RRGP----------HPDFPDDFSRPDDFHP-----------DKRFG-HRLREFEGRGGP- 1038 GP P FP + + D P D + G L G GP Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH 443 Query: 1039 -LPQEEKWRRGGPGPPFPPDHREFS-----EGD---------GRGAARGPPGAWEGRRPG 1083 P +E G PGPP P + +GD G G + GPPG +PG Sbjct: 444 IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS-GPPG-----QPG 497 Query: 1084 DERFPRDPEDPRFRGRREESFRRGA--PPRHEGRAPPRGRDGFPG----PEDF--GPEEN 1135 P P F G++ E + GA P G G GFPG P D P Sbjct: 498 LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK 557 Query: 1136 FDASEEAARGRDLRGRGRGTPRGGRKGL--LPTPDEFP---RFEGGRKPDSWDGNREPGP 1190 D E + G GTP G+ GL LP P P F+G R P GN P Sbjct: 558 GDKGELGSPGAPGLPGLPGTP--GQDGLPGLPGPKGEPGGITFKGERGP---PGN----P 608 Query: 1191 GHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAP 1250 G P PP G P +QG +A P +P GP + + P Sbjct: 609 GLPGLPGNIGPMGPP--GFGPPGPVGEKGIQG--VAGNP--GQPGIPGPKGDPGQTITQP 662 Query: 1251 GGPSEDRGGKGRGG----PG----PAQ----RVPKSGRSSSLDGEHHDGYHRDEPF---G 1295 G P G GR G PG P Q +P S + G G + F Sbjct: 663 GKPGLP-GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721 Query: 1296 GPPGS-GTPSRGGRSG 1310 GPPG+ GTP R G G Sbjct: 722 GPPGAPGTPGRIGLEG 737 Score = 131 bits (329), Expect = 5e-30 Identities = 94/248 (37%), Positives = 108/248 (43%), Gaps = 32/248 (12%) Query: 574 PPPSSGTPLLGPQPFPG-QGPMSQI-PQGFQQ---PHPSQQMPMNMAQMGPPGPQGQFRP 628 PP S G L GP+ PG QGP + P GFQ P +P N G G GQ Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1298 Query: 629 PGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLG 688 PG G G QGPP QG G G G +G G P G+P M GP G+ GP G G Sbjct: 1299 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP-GVPGFPGMKGPSGVPGSAGPEGEPG 1357 Query: 689 PQGPPGPQGSSGPQGH-------------------------MGPQGPPGPQGHIGPQGPP 723 GPPGP G GP G GPQG PGP G G G Sbjct: 1358 LIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN 1417 Query: 724 GPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRG 783 G G G G G G+ G PG RG+ GPP P G+QG PG G V+ G L+ + + Sbjct: 1418 GLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS-VAHGFLITRHSQT 1476 Query: 784 MQGPPGPR 791 P P+ Sbjct: 1477 TDAPQCPQ 1484 Score = 53.5 bits (127), Expect = 1e-06 Identities = 127/498 (25%), Positives = 160/498 (32%), Gaps = 94/498 (18%) Query: 844 SMLGPPQELRG----PPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP 899 S+ G P E PGS+ +G G G++G PG G P Sbjct: 18 SLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGP---------- 67 Query: 900 IPFQQQKTPLLGDGPRAPFNQEGQS--TGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKG 957 +GP P Q+G GPP G +G +G PP PG P Sbjct: 68 ------------EGPPGPRGQKGDDGIPGPP------GPKGIRG--PPGLPG---FPGTP 104 Query: 958 DSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPD 1017 G P H P GP+ G C G RG FP P Sbjct: 105 GLPGMPGHDGAP----------GPQ---------GIPGCNGTKGERG----FPGSPGFPG 141 Query: 1018 DFHPDKRFGHRLREFEGRGGPLPQEE-KWRRGGPGPPFPPDHREFSEGDGRGAARGPPGA 1076 P G + +G G + +G PG P PP + G GPPG Sbjct: 142 LQGPPGPPG--IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 1077 WEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENF 1136 PG P P P +G +F+ P +G +G G PGP E+ Sbjct: 200 -----PGLMGPPGPPGLPGPKGNMGLNFQ--GPKGEKGE---QGLQGPPGPPGQISEQKR 249 Query: 1137 DASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFR 1196 E +G RG P G G+ P P E G K + + + PG + Sbjct: 250 PIDVEFQKGDQGLPGDRGPP--GPPGIRGPPGP-PGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 1197 DTPRPDHPPHDGHSPA--SRERSSSLQGMDMASLPPRKRPWHDGPGTS--EHREMEAPGG 1252 P P D P R+ +G PP G G + E + PG Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 1253 PSE--DRGGKG-RGGPG----PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSR 1305 P E +RG G +G PG P V GE G DE GPPG P Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER--GQKGDE---GPPGISIPGP 421 Query: 1306 GGRSGSNWGRGSNMNSGP 1323 G G G GP Sbjct: 422 PGLDGQPGAPGLPGPPGP 439 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 218 bits (555), Expect = 3e-56 Identities = 254/803 (31%), Positives = 305/803 (37%), Gaps = 131/803 (16%) Query: 574 PPPSSGTP----LLGPQPFPG-QGPMSQIPQGFQQPHPSQQ--MPMNMAQMGPPGPQGQF 626 PP + GTP L GP PG GP + GF P P +P +GP G +G Sbjct: 723 PPGAPGTPGRIGLEGPPGPPGFPGPKGE--PGFALPGPPGPPGLPGFKGALGPKGDRGFP 780 Query: 627 RPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP----QGLPRPQDMHGPQGMQRHPG 682 PPGP G+ G G P +G GP G GP GP G P QG P P + GP G PG Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQ---PG 837 Query: 683 PHGPLGPQGPPGPQGSS--GPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQG- 739 HG G +G PGP G GP G G G PG G IGP G PG G G G PGT+G Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGE 897 Query: 740 --MQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-PVSQGPLMGLNPRGMQGPPGPRENQGP 796 M GPPGP G G P G+ G G G+QG P GP +G G PGP P Sbjct: 898 MGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGP-----P 952 Query: 797 APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPP 856 P + E P PG + GP+ +G+ G P Q + G P L GPP Sbjct: 953 GPMDPNLLGSKGEKGEPGLPG------IPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPP 1005 Query: 857 GSQSQQGPP--QGSLGPPPQGGMQGP---PGPQGQQNPARGPHPSQGPIPFQQQKTPLLG 911 G + G P G +GPP G G PGPQG + P P +P Q L G Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP-----PGPSGVPGQPGSPGLPG 1060 Query: 912 DGPRAPFNQEGQSTGPPPLIPGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPM 970 Q+G P GL G G +G P PG P S G P P Sbjct: 1061 --------QKGDKGDPGISSIGLPGLPGPKGE--PGLPGYPGNPGIKGSVGDPGLPGLPG 1110 Query: 971 SERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLR 1030 + Q G P GP G + GPP G P + P GH Sbjct: 1111 TPGAKGQPGLPGFPGTPGP-PGPKGISGPPGNPG----------LPGEPGPVGGGGHP-- 1157 Query: 1031 EFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPG--AWEGRRPGDERFP 1088 G P P EK + G G P P + G G GPPG G++ GD P Sbjct: 1158 -----GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP-GPPGLPGLSGQK-GDGGLP 1210 Query: 1089 RDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDL 1148 P +P G + E G P G P G G PGP GP+ N +G Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFP----GVQGPPGPPGSPGPALEGPKGN-----PGPQGPPG 1261 Query: 1149 RGRGRGTP----------RGGRKGLLPTPDE-----FPRFEGGRKPDSWDGNREPG-PGH 1192 R +G P GG KG P + P +G + P GN PG PG Sbjct: 1262 RPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN--PGRPGL 1319 Query: 1193 EHFRDTPR-PDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSE---HREME 1248 + P P P G S S+ + + P P GP + Sbjct: 1320 NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAG 1379 Query: 1249 APGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGR 1308 PG P + G KG GP Q +P GPPG P R G Sbjct: 1380 PPGIPGQP-GLKGLPGPQGPQGLPGPT--------------------GPPGD--PGRNGL 1416 Query: 1309 SGSNWGRGSNMNSGPPRRGASRG 1331 G + G + G P + +RG Sbjct: 1417 PGFDGAGGRKGDPGLPGQPGTRG 1439 Score = 209 bits (532), Expect = 1e-53 Identities = 246/791 (31%), Positives = 303/791 (38%), Gaps = 114/791 (14%) Query: 616 QMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQG--PPQGLPRPQDMHG 673 + G PG +G PG G GP+GPP +G G G GP GP+G P GLP Sbjct: 49 ERGFPGLEGH---PGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP------- 98 Query: 674 PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQG 733 G PG G G G PGPQG G G G +G PG G G QGPPGP G G +G Sbjct: 99 --GFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKG 156 Query: 734 PPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVS-QGPLMGLNPRGMQGPPGPRE 792 PG+ M PGP+G G P P GIQG PG GI GP+ GP + P G G PGP+ Sbjct: 157 EPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKG 216 Query: 793 NQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEM-----RGPQEIRGMQGPPPQGSMLG 847 N G QG Q ++GP P G + + + +G Q + G +GPP + G Sbjct: 217 NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 848 PPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG-QQNPARGPHPSQGPIPFQQQK 906 PP G G + +QG P G G P + G G PG G +P P + Q+ Sbjct: 277 PPGPPGGEKGEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335 Query: 907 T-PLLGDGPRAPFNQEGQSTGPPPLI--PGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGP 962 T P G P G + G I PGL G++G +G P PGP GP Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395 Query: 963 PNHHMGPMSERRHEQSGGPEHGPERGP-----FRGGQDCRGPPDRRGPHPDFPDDFSRPD 1017 P P ER + GP GP G GPP GPH D+ P Sbjct: 396 PGPPGFP-GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPG 454 Query: 1018 DFHPDKRFGHRLREFE---------------GRGGPLPQEEKWRRGGPGPP----FPPDH 1058 P G + + E G G P + G PGPP FP Sbjct: 455 PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQK 514 Query: 1059 REFSEGDGRG--AARGPPGAWEGRRPGDERFP---RDPED----PRFRGRREESFRRGAP 1109 E + G G PGA PG FP +P D P +G + E GAP Sbjct: 515 GEKGQAGATGPKGLPGIPGA-----PGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 1110 --PRHEGRAPPRGRDGFPGPE----------DFGPEENFDASEEAARGRDLRGRGRGTP- 1156 P G G G PGP+ + GP N + G G P Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 1157 ---RGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPG-------PGHEHFRDTPRPDHPPH 1206 G +G+ P + P G K D +PG PG + D P P Sbjct: 630 PVGEKGIQGVAGNPGQ-PGIP-GPKGDPGQTITQPGKPGLPGNPGRD--GDVGLPGDPGL 685 Query: 1207 DGHS-----PASRERSSSLQGMDMASLP-PRKRPWHDG----PGTSEHREMEAPGGPSED 1256 G P S+ + G+ + P P+ P G PGT +E P GP Sbjct: 686 PGQPGLPGIPGSK-GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGF 744 Query: 1257 RGGKGRGG---PGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNW 1313 G KG G PGP G +L G D F GPP G P R G G Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGAL------GPKGDRGFPGPP--GPPGRTGLDGLPG 796 Query: 1314 GRGSNMNSGPP 1324 +G +G P Sbjct: 797 PKGDVGPNGQP 807 Score = 207 bits (526), Expect = 7e-53 Identities = 211/665 (31%), Positives = 254/665 (38%), Gaps = 111/665 (16%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP-- 631 PP G+P + P P P S G M MGPPGP G PG Sbjct: 858 PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917 Query: 632 ----------QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHP 681 QGQ G GP +G G G GP GP P L + G G+ P Sbjct: 918 VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDP--NLLGSKGEKGEPGLPGIP 975 Query: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQ 741 G GP G QG PG G G G G GPPGP+G+ G PG G +GP G GT G Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN---PGLPGQPGLIGPPGLKGTIGDM 1032 Query: 742 GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGM 801 G PGP+G++GPP P G+ G PGS G+ G G++ G+ G PGP+ G Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPG------ 1086 Query: 802 IMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQ 861 + G+P PG G + G G +G P G P GPPG Sbjct: 1087 LPGYPGN-------PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP----GPPG---- 1131 Query: 862 QGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQE 921 P+G GPP G+ G PGP G G HP Q P ++ K DG P Q+ Sbjct: 1132 ---PKGISGPPGNPGLPGEPGPVG-----GGGHPGQPGPPGEKGKPG--QDGIPGPAGQK 1181 Query: 922 GQSTGP------PPLIPGLGQQGAQGRIP--PLNPGQGPGPNKGDSRGPPNHHMGPMSER 973 G+ P PP +PGL Q G +P P NPG PGP +G P H P + Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL-PGP-----KGEPGFHGFPGVQG 1235 Query: 974 RHEQSGGPEHGPERGPFRGGQDCRGPPDRRG----PHPDFPDDFSRPDDFHPDKRFGHRL 1029 G P GP +G +GPP R G P P+ P Sbjct: 1236 PPGPPGSP--GPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPG----------------- 1276 Query: 1030 REFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPR 1089 G GG K +G PG P P G +G PG RPG Sbjct: 1277 --LPGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG-----RPGLNGMKG 1324 Query: 1090 D---PEDPRFRGRREESFRRGA--PPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAAR 1144 D P P F G + S G+ P G P G G PGP DA Sbjct: 1325 DPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIP 1384 Query: 1145 GR-DLRG-RGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWD--GNREPGPGHEHFRDTPR 1200 G+ L+G G P+G LP P P G +D G R+ PG T Sbjct: 1385 GQPGLKGLPGPQGPQG-----LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRG 1439 Query: 1201 PDHPP 1205 D PP Sbjct: 1440 LDGPP 1444 Score = 194 bits (492), Expect = 6e-49 Identities = 253/853 (29%), Positives = 306/853 (35%), Gaps = 205/853 (24%) Query: 618 GPPGPQGQFRPPG------PQGQMGPQGPPLHQGGGGPQ------------------GFM 653 GPPGP+G PPG G G G H G GPQ GF Sbjct: 84 GPPGPKGIRGPPGLPGFPGTPGLPGMPG---HDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 654 GPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGP 713 G QGP GPP G+P + G M PGP G G GPPG QG GP G GP GPPGP Sbjct: 141 GLQGPPGPP-GIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 714 QGHIGPQGP---PGPQGHL-----GPQGPPGTQGMQGPPGP----------------RGM 749 G +GP GP PGP+G++ GP+G G QG+QGPPGP +G Sbjct: 200 PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGD 259 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMG-LNPRGMQGPPGPR-------ENQGPAPQGM 801 QG P G +G PG GI+GP GP G +G QG PG R EN P G+ Sbjct: 260 QGLP---GDRGPPGPPGIRGP--PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGL 314 Query: 802 --IMGHPPQEMR----------GPHPPGGLL----GHG--------------PQEMRGPQ 831 G+P + R GP P GL+ G G P E +G + Sbjct: 315 PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE-KGER 373 Query: 832 EIRGMQGP-----PPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQ 886 G+QGP PP +++GPP GPPG ++G +G GPP + GPPG GQ Sbjct: 374 GFPGIQGPPGLPGPPGAAVMGPP----GPPGFPGERG-QKGDEGPPGI-SIPGPPGLDGQ 427 Query: 887 QNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPL 946 P P GP GP P + E GPP G +G QG Sbjct: 428 PGAPGLPGP-PGPA------------GPHIPPSDEICEPGPPGPPGSPGDKGLQGE---- 470 Query: 947 NPGQGPGPNKGDS---------RGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCR 997 QG +KGD+ GPP P G P E+G G + Sbjct: 471 ---QGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ-AGATGPK 526 Query: 998 GPPDRRGP--HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFP 1055 G P G P FP P D + F G G +K G PG P Sbjct: 527 GLPGIPGAPGAPGFPGSKGEPGD----------ILTFPGMKG-----DKGELGSPGAPGL 571 Query: 1056 PDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAP------ 1109 P DG GP G G ER P P +P G G P Sbjct: 572 PGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP--PGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 1110 ----PRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLP 1165 +G A G+ G PGP+ + + G R G P G G LP Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLP--GDPG-LP 686 Query: 1166 TPDEFPRFEGGRKPDSWDGNREPG-PGHEHFRDTPRP------------DHPPHDGHSPA 1212 P G + G PG PG + F P P + PP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 1213 SRERSS----------SLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGR 1262 + L G A P R + PG ++ GP D G G+ Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ 806 Query: 1263 GGPGPAQRVPKSGRSS-----------SLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGS 1311 GP +P G G H + +P GPPG P G GS Sbjct: 807 PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP--GPPGLDVPGPPGERGS 864 Query: 1312 NWGRGSNMNSGPP 1324 G+ GPP Sbjct: 865 PGIPGAPGPIGPP 877 Score = 189 bits (480), Expect = 2e-47 Identities = 182/549 (33%), Positives = 223/549 (40%), Gaps = 92/549 (16%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 PP LLG + G+ + IP G P Q +P + Q G G G PPGP+G Sbjct: 951 PPGPMDPNLLGSKGEKGEPGLPGIP-GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009 Query: 634 ------QMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----------QGLPRPQDMHGPQG 676 Q G GPP +G G GF GPQG +GPP GLP + G G Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069 Query: 677 MQRH--PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP 734 + PG GP G G PG G+ G +G +G G PG G G +G PG G G GP Sbjct: 1070 ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP 1129 Query: 735 PGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGL-NPRGMQGPPGPREN 793 PG +G+ GPPG G+ G P P G G PG G G + G+ P G +G PG Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189 Query: 794 QGPAPQGMIMGHPPQEMRGPHP--PGGLLGHGPQEMRGPQEIRGMQGPP-PQGSMLGPPQ 850 P P G+ G Q+ G P PG GP+ G G+QGPP P GS P Sbjct: 1190 GNPGPPGL-PGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS---PGP 1245 Query: 851 ELRGPPGSQSQQGPP-----QGSLGPPPQGGMQGPPGPQGQQ-NPARGPHPSQGPIPFQQ 904 L GP G+ QGPP QG GP G+ G G +G++ NP + P + Q Sbjct: 1246 ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305 Query: 905 QKTPLLGDGPRAPFNQEGQSTGPP--PLIPGL----------GQQGAQGRIPPLNPGQGP 952 L G+ R N G P P PG+ G +G G I P P P Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1365 Query: 953 GPN------KGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPH 1006 GP+ KGD+ GPP G P G Q +G P GP Sbjct: 1366 GPSGQSIIIKGDA-GPP----------------GIPGQPGLKGLPGPQGPQGLPGPTGP- 1407 Query: 1007 PDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDG 1066 P D R + L F+G GG R+G PG P P R G Sbjct: 1408 ---PGDPGR-----------NGLPGFDGAGG--------RKGDPGLPGQPGTRGLDGPPG 1445 Query: 1067 RGAARGPPG 1075 +GPPG Sbjct: 1446 PDGLQGPPG 1454 Score = 177 bits (448), Expect = 8e-44 Identities = 141/368 (38%), Positives = 171/368 (46%), Gaps = 59/368 (16%) Query: 575 PPSSGTPLLGPQP----FPGQGPMSQIPQGFQQPHPSQQMPM---------NMAQMGPPG 621 P GTP QP FPG P P+G P + +P + Q GPPG Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGT-PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 622 PQG---QFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQG 676 +G Q PGP GQ G G P G GP G G G +G G+P + GP+G Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223 Query: 677 MQRHPGPHGPLGPQGPPGPQGS-----SGPQGHMGPQGPPGP---QGHIGPQGPPGPQGH 728 PG HG G QGPPGP GS GP+G+ GPQGPPG QG GP+GPPG G+ Sbjct: 1224 ---EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGN 1280 Query: 729 LGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNP-RGMQGP 787 G +G G G G PG G++G P G+QG PG G+ G L G+ GM+GP Sbjct: 1281 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1340 Query: 788 PGPRENQGPAPQGMIMGHP-PQEMRGPH-----------PPG-----GLLG-HGPQEMRG 829 G + GP + ++G P P + GP PPG GL G GPQ G Sbjct: 1341 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ---G 1397 Query: 830 PQEIRGMQGPPPQGSMLGPPQ-----ELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQ 884 PQ + G GPP G P +G PG Q G +G GPP G+QGPPGP Sbjct: 1398 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT-RGLDGPPGPDGLQGPPGPP 1456 Query: 885 GQQNPARG 892 G + A G Sbjct: 1457 GTSSVAHG 1464 Score = 173 bits (439), Expect = 9e-43 Identities = 236/779 (30%), Positives = 281/779 (36%), Gaps = 122/779 (15%) Query: 618 GPPGPQGQFRPPGPQGQMG---PQGPPLHQGGGGPQGFMGPQGPQGPPQGLP----RPQD 670 GPPG G PGP G +G +G G GP+G G G G P G P P D Sbjct: 491 GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAP-GFPGSKGEPGD 549 Query: 671 MHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHI---GPQGPPGPQG 727 + GM+ G G G G PG G+ G G G GP G G I G +GPPG G Sbjct: 550 ILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609 Query: 728 ------HLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGP-------VSQG 774 ++GP GPPG GPPGP G +G G+ G PG GI GP ++Q Sbjct: 610 LPGLPGNIGPMGPPGF----GPPGPVGEKG---IQGVAGNPGQPGIPGPKGDPGQTITQP 662 Query: 775 PLMGL--NPR-----GMQGPPGPRENQG----PAPQGMIMGHPPQEMRGPHPPGGLLG-H 822 GL NP G+ G PG G P +G G P + GP P G G Sbjct: 663 GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE-PGIPGIGLPGPPGPKGFPGIP 721 Query: 823 GPQEMRGPQEIRGMQGPPPQGSMLGPPQE----LRGPPGSQSQQGPPQGSLGPPPQGGMQ 878 GP G G++GPP GP E L GPPG G +G+LGP G Sbjct: 722 GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPG-FKGALGPKGDRGFP 780 Query: 879 GPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEG---QSTGPPPLIPG-L 934 GPPGP G+ P P P Q GP P G Q PP IPG + Sbjct: 781 GPPGPPGRTGLDGLPGPKGDVGPNGQ-------PGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 935 GQQGAQGRIPPLNPGQ--GPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHG--PERGPF 990 GQ G G PG+ PGP D GPP P G P P + Sbjct: 834 GQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888 Query: 991 RGGQDCRGPPDRRGPHPDFPDDFSRPD-DFHPDKRFGHRLREFEGRGGPLPQE-EKWRRG 1048 G +G GP P P P P + L+ G GP ++ K G Sbjct: 889 SGFPGTKGEMGMMGP-PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG 947 Query: 1049 GPGPPFPPDHREF-SEGD-GRGAARGPPG-----AWEGRRPGDERFPRDPEDPRFRGRRE 1101 PGPP P D S+G+ G G PG ++G PGD P P G Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQG-LPGDPGQPGLSGQPGLPGPPG 1006 Query: 1102 ESFRRGAPPRHEGRAPPR-----GRDGFPGPE--DFGPEENFDASEEAARGRDLRGRGRG 1154 G P + PP G GFPGP+ + P + + + G + +G Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 1155 TPRGGRKGL--LPTPDEFPRFEGGRKPDSWDGNREPG-------PGHEHFRDTPRPDHPP 1205 P GL LP P P G + GN PG PG TP P Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPG------YPGN--PGIKGSVGDPGLPGLPGTPGAKGQP 1118 Query: 1206 HDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGP 1265 L G PP + PG PG P GG G P Sbjct: 1119 -------------GLPGFPGTPGPPGPKGISGPPGNP-----GLPGEPGPVGGGGHPGQP 1160 Query: 1266 GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 GP K G+ G FG P G P G+ G G N G P Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLP 1219 Score = 164 bits (414), Expect = 7e-40 Identities = 228/736 (30%), Positives = 281/736 (38%), Gaps = 163/736 (22%) Query: 699 SGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGI 758 SG +G G +G PG +GH G G PGP+G GP+G G G+ GPPGP+G++GPP G Sbjct: 41 SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100 Query: 759 QGGPGSQGIQG----PVSQGPLMGLNPR-------------GMQGPPGPRENQG--PAPQ 799 G PG G+ G P QG + G N G+QGPPGP G P Sbjct: 101 PGTPGLPGMPGHDGAPGPQG-IPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPG 159 Query: 800 GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQ 859 +IM P P PG G Q + GP I G GPP ++GPP GPPG Sbjct: 160 SIIMSSLPGPKGNPGYPG---PPGIQGLPGPTGIPGPIGPPGPPGLMGPP----GPPGLP 212 Query: 860 SQQGPP----QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD-GP 914 +G QG G + G+QGPPGP GQ + + P + FQ+ L GD GP Sbjct: 213 GPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPI----DVEFQKGDQGLPGDRGP 268 Query: 915 RAPFNQEGQSTGPPPLIPG--LGQQGAQG----RIPPLNPGQGPGPNKGDSRGPPNHHMG 968 P G PP PG G++G QG R P G+ P G P + Sbjct: 269 PGPPGIRG-----PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323 Query: 969 PMSERRHEQSG--GPEHGP--------------ERGPF-----------RGGQDCRGPPD 1001 P + Q G GP P E+G RG +GPP Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383 Query: 1002 RRGP----------HPDFPDDFSRPDDFHP-----------DKRFG-HRLREFEGRGGP- 1038 GP P FP + + D P D + G L G GP Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH 443 Query: 1039 -LPQEEKWRRGGPGPPFPPDHREFS-----EGD---------GRGAARGPPGAWEGRRPG 1083 P +E G PGPP P + +GD G G + GPPG +PG Sbjct: 444 IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS-GPPG-----QPG 497 Query: 1084 DERFPRDPEDPRFRGRREESFRRGA--PPRHEGRAPPRGRDGFPG----PEDF--GPEEN 1135 P P F G++ E + GA P G G GFPG P D P Sbjct: 498 LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMK 557 Query: 1136 FDASEEAARGRDLRGRGRGTPRGGRKGL--LPTPDEFP---RFEGGRKPDSWDGNREPGP 1190 D E + G GTP G+ GL LP P P F+G R P GN P Sbjct: 558 GDKGELGSPGAPGLPGLPGTP--GQDGLPGLPGPKGEPGGITFKGERGP---PGN----P 608 Query: 1191 GHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAP 1250 G P PP G P +QG +A P +P GP + + P Sbjct: 609 GLPGLPGNIGPMGPP--GFGPPGPVGEKGIQG--VAGNP--GQPGIPGPKGDPGQTITQP 662 Query: 1251 GGPSEDRGGKGRGG----PG----PAQ----RVPKSGRSSSLDGEHHDGYHRDEPF---G 1295 G P G GR G PG P Q +P S + G G + F Sbjct: 663 GKPGLP-GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721 Query: 1296 GPPGS-GTPSRGGRSG 1310 GPPG+ GTP R G G Sbjct: 722 GPPGAPGTPGRIGLEG 737 Score = 130 bits (328), Expect = 6e-30 Identities = 92/245 (37%), Positives = 106/245 (43%), Gaps = 29/245 (11%) Query: 574 PPPSSGTPLLGPQPFPG-QGPMSQIP-QGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP 631 PP S G L GP+ PG QGP + QG P +P N G G GQ PG Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1298 Query: 632 QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQG 691 G G QGPP QG G G G +G G P G+P M GP G+ GP G G G Sbjct: 1299 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP-GVPGFPGMKGPSGVPGSAGPEGEPGLIG 1357 Query: 692 PPGPQGSSGPQGH-------------------------MGPQGPPGPQGHIGPQGPPGPQ 726 PPGP G GP G GPQG PGP G G G G Sbjct: 1358 PPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1417 Query: 727 GHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQG 786 G G G G G+ G PG RG+ GPP P G+QG PG G V+ G L+ + + Sbjct: 1418 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS-VAHGFLITRHSQTTDA 1476 Query: 787 PPGPR 791 P P+ Sbjct: 1477 PQCPQ 1481 Score = 53.5 bits (127), Expect = 1e-06 Identities = 127/498 (25%), Positives = 160/498 (32%), Gaps = 94/498 (18%) Query: 844 SMLGPPQELRG----PPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP 899 S+ G P E PGS+ +G G G++G PG G P Sbjct: 18 SLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGP---------- 67 Query: 900 IPFQQQKTPLLGDGPRAPFNQEGQS--TGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKG 957 +GP P Q+G GPP G +G +G PP PG P Sbjct: 68 ------------EGPPGPRGQKGDDGIPGPP------GPKGIRG--PPGLPG---FPGTP 104 Query: 958 DSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPD 1017 G P H P GP+ G C G RG FP P Sbjct: 105 GLPGMPGHDGAP----------GPQ---------GIPGCNGTKGERG----FPGSPGFPG 141 Query: 1018 DFHPDKRFGHRLREFEGRGGPLPQEE-KWRRGGPGPPFPPDHREFSEGDGRGAARGPPGA 1076 P G + +G G + +G PG P PP + G GPPG Sbjct: 142 LQGPPGPPG--IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199 Query: 1077 WEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENF 1136 PG P P P +G +F+ P +G +G G PGP E+ Sbjct: 200 -----PGLMGPPGPPGLPGPKGNMGLNFQ--GPKGEKGE---QGLQGPPGPPGQISEQKR 249 Query: 1137 DASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFR 1196 E +G RG P G G+ P P E G K + + + PG + Sbjct: 250 PIDVEFQKGDQGLPGDRGPP--GPPGIRGPPGP-PGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 1197 DTPRPDHPPHDGHSPA--SRERSSSLQGMDMASLPPRKRPWHDGPGTS--EHREMEAPGG 1252 P P D P R+ +G PP G G + E + PG Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 1253 PSE--DRGGKG-RGGPG----PAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSR 1305 P E +RG G +G PG P V GE G DE GPPG P Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGER--GQKGDE---GPPGISIPGP 421 Query: 1306 GGRSGSNWGRGSNMNSGP 1323 G G G GP Sbjct: 422 PGLDGQPGAPGLPGPPGP 439 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 215 bits (548), Expect = 2e-55 Identities = 249/857 (29%), Positives = 313/857 (36%), Gaps = 169/857 (19%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--------------- 662 GPPGP G PGP G+ GP+G P G G G GP+GP+G P Sbjct: 495 GPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQ 554 Query: 663 --QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQ 720 GL P M G +G++ HPG G G QG PG G+ G G+ G QG GP+G+ GP+ Sbjct: 555 GLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPK 614 Query: 721 ------GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPP------HPHGIQGGPGSQGIQ 768 G PG G LGP+G G G++G G +G QG P P G+ G PG G Sbjct: 615 GAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGT 674 Query: 769 GPV-------SQGPLMGLNPRGMQGPPGPRENQG----------------------PAPQ 799 GP S GP+ + P G+ GP G N+G P + Sbjct: 675 GPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDK 734 Query: 800 GMIMGHPPQEMRGPHPPGGLLG----HGPQEMRGPQEIRGMQGPPPQGSMLGPPQEL--R 853 G + P MRG P G G GP GP+ G G P Q GP L R Sbjct: 735 GAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNR 794 Query: 854 GPP------GSQSQQGP--PQGSLGP---PPQGGMQGPPGPQGQQNPAR-----GPHPSQ 897 GPP G+Q ++GP G LGP P Q G G PGP+G + G Sbjct: 795 GPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGET 854 Query: 898 GPI--PFQQQKTPLLGD-------GPRAPFNQEGQSTGP-PPLIPG-LGQQGAQGRIPPL 946 GP+ P + T +G+ GP P ++G P PP +PG +G G G + Sbjct: 855 GPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGAR 914 Query: 947 NP--GQGPGPNKGDSRGP-----PNHHMGPMSERRHEQSGGPEHG-------PERGPFRG 992 P QGP +G SRGP G E+ + GP HG P F+G Sbjct: 915 GPPGSQGPKGQRG-SRGPDGLLGEQGIQGAKGEKGDQGKRGP-HGLIGKTGNPGERGFQG 972 Query: 993 GQDCRGPPDRRGPH--PDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGP 1050 +G P G P P D P G G P + E +G P Sbjct: 973 KPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGM-------EGPPGTEGESGLQGEP 1025 Query: 1051 GPPFPPDHREFSEGDGRGAARGPPGA-WEGRRPGDERFPRDPEDPRFRGRREESFRRGAP 1109 G G G RG PGA E G + P G E G P Sbjct: 1026 GAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLP 1085 Query: 1110 PRHEGRAPPRGRD---GFPGPEDF--------GPEENFDASEEAARGR-DLRGRGRGTPR 1157 G P GR G PGPE P + D + G RG + Sbjct: 1086 ----GIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGK 1141 Query: 1158 GGRKGLLPTPDEFPRFEGGRKPDSWDGNREPG-PGHEHFRDTPRPDHPPHDGHSPASRER 1216 G KG T G PD EPG PG+ + P P P Sbjct: 1142 SGPKGARGTRGAVGHL-GLMGPDG-----EPGIPGYRGHQGQPGPSGLPGPKGEKGYPGE 1195 Query: 1217 SSSLQGMDMASLPP--------RKRPWHDG-------PGTSEHREMEAPGGPSEDRGGKG 1261 S++ G P R P +G PG + P G D+G +G Sbjct: 1196 DSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQG 1255 Query: 1262 -------------RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS-GTPSRGG 1307 +G PGP+ + G L + GYH + G PG G P + G Sbjct: 1256 LKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQG 1315 Query: 1308 RSGSNWGRGSNMNSGPP 1324 G G G +G P Sbjct: 1316 LPGIRGGPGRTGLAGAP 1332 Score = 206 bits (523), Expect = 2e-52 Identities = 244/855 (28%), Positives = 316/855 (36%), Gaps = 189/855 (22%) Query: 583 LGPQPFPGQGPMSQ---IPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQG 639 +GP PG +S +P G + Q + + G PG +G PGP G G G Sbjct: 692 IGPAGIPGPMGLSGNKGLP-GIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSG 750 Query: 640 PPLHQGGGGPQGFMGPQGPQGPPQ--GLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQG 697 P G G QG GP GP+G P G+P GP+G+ + GP GP G +G G +G Sbjct: 751 PSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEG 810 Query: 698 SSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP------------PGTQGMQGPPG 745 G G +GP+G PG +G+ G GP G +G +G QG PG GM G G Sbjct: 811 PIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIG 870 Query: 746 PRGMQGPPHPHGIQGGPGSQGIQGPVS-QGPLMGLNPRGMQGPPGPRENQGPAPQGMIMG 804 +G +G P P G QG G G GP GP+ L G G GP +QGP Q Sbjct: 871 EKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQ----- 925 Query: 805 HPPQEMRGPHPPGGLLGH----------GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRG 854 RG P GLLG G Q RGP + G G P + G P L+G Sbjct: 926 ------RGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKP-GLQG 978 Query: 855 PPGSQSQQGPP--------QGSLGPPPQGGMQGPPGPQGQ-----QNPARGPHPSQGPI- 900 PGS +G P QG +GPP + GM+GPPG +G+ + A+G + G + Sbjct: 979 LPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVG 1038 Query: 901 -------------PFQ---QQKTPLLG-DGPRAPFNQEGQ--STGPPPLIPGLGQQGAQG 941 P + Q K L G G R ++G+ G P +I LG+ G G Sbjct: 1039 GTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTG 1098 Query: 942 RIPPLN----PGQGPGP-NKGD-----------SRGPPNH--HMGPMSER------RHEQ 977 P PGQ P KGD SRGPP GP R H Sbjct: 1099 LPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLG 1158 Query: 978 SGGPEHGPERGPFRGGQDCRGPPDRRGPHPD--FPDDFSRPDDFHPDKRFGHRLREFEGR 1035 GP+ P +RG Q GP GP + +P + S L R Sbjct: 1159 LMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTV------------LGPPGPR 1206 Query: 1036 GGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPR 1095 G P P ++ RG PG H G +GPPG PGD+ + Sbjct: 1207 GEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPG-----EPGDQ------GEQG 1255 Query: 1096 FRGRREESFRRGAPPRHEGRAPPRGRDGFPGPED-FGPEENFDASEEAARGRDLRGRGRG 1154 +G R +G +G P G+ G PG + GP + ++G Sbjct: 1256 LKGERGSEGNKG----KKGAPGPSGKPGIPGLQGLLGP-------------KGIQGYHGA 1298 Query: 1155 TPRGGRKGLLPTPDE--FPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPA 1212 G G + P + P G GPG P P Sbjct: 1299 DGISGNPGKIGPPGKQGLPGIRG-------------GPGRTGLAGAP----------GPP 1335 Query: 1213 SRERSSSLQGMDMASLPPRKRPWHDGPGTS---EHREMEAPGGPSEDRGGKGRGG----- 1264 + SS L G P ++ PG HR + GP D G KG+ G Sbjct: 1336 GVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQ 1395 Query: 1265 --------PGP------AQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG-SGTPSRGGRS 1309 PGP A V SG + + G E GP G +G G Sbjct: 1396 GLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFR 1455 Query: 1310 GSNWGRGSNMNSGPP 1324 G +G GPP Sbjct: 1456 GETGPQGPRGQPGPP 1470 Score = 178 bits (451), Expect = 4e-44 Identities = 140/404 (34%), Positives = 181/404 (44%), Gaps = 39/404 (9%) Query: 582 LLGPQPFPGQ----GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGP 637 ++GP GQ GP + Q+ P ++ + Q+GP G G PPG G+ GP Sbjct: 1087 IIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKG--DKGQIGPTGEVGSRGPPGKIGKSGP 1144 Query: 638 QGPPLHQGGGGPQGFMGPQGPQGPP-----QGLPRPQDMHGPQGMQRHPGPHGPLGPQGP 692 +G +G G G MGP G G P QG P P + GP+G + +PG + GP Sbjct: 1145 KGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTV--LGP 1202 Query: 693 PGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGP 752 PGP+G GP G G +G PG +G+ G G PG +G G QGPPG G QG G +G +G Sbjct: 1203 PGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGS 1262 Query: 753 PHPHGIQGGPGSQGIQG-PVSQGPLMGLNPRGMQGPPGPRENQG----PAPQGMIMGHPP 807 G +G PG G G P QG L +G G G N G P QG+ P Sbjct: 1263 EGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGL-----P 1317 Query: 808 QEMRGPHPPGGLLGHGPQEMRGPQEIRG---MQGPPPQGSMLGPP--QELRGPPGSQSQQ 862 GP G GP ++G + G +QGP + + G P Q RG G+Q Q Sbjct: 1318 GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ 1377 Query: 863 GP--PQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQ 920 GP G G P + G+QG G QG P +GP G + K P+ G P + Sbjct: 1378 GPCGDPGLKGQPGEYGVQGLTGFQGFPGP-KGPEGDAGIVGISGPKGPIGHRGNTGPLGR 1436 Query: 921 EG-----QSTGP---PPLIPGLGQQGAQGRIPPLNPGQGPGPNK 956 EG TGP G QG +G+ P P PGP K Sbjct: 1437 EGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRK 1480 Score = 167 bits (423), Expect = 6e-41 Identities = 222/721 (30%), Positives = 268/721 (37%), Gaps = 118/721 (16%) Query: 669 QDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGH 728 +D++ M+ GP G GP GPPGP G GP G GP+G PGP G+ G G PGP+G Sbjct: 476 EDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGP 535 Query: 729 LGP---------QGPPGTQGMQGPPGPRGMQGPP----HPHGIQGGPGSQGIQGPVSQGP 775 G G G QG+ G GP GMQG HP G+ G PG QGI G G Sbjct: 536 KGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHP-GLPGLPGEQGIPG--FAGN 592 Query: 776 LMGLNPRGMQGPPGPRENQGP-APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIR 834 + G QG GP N GP QG I GP G+ G +RG + + Sbjct: 593 IGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPG-----IRGKKGFK 647 Query: 835 GMQGPPPQGSMLGPPQELRGPPGSQSQQGPP-----QGSLGPPPQGGMQGPPGPQGQQN- 888 G QG P G P L G PG GPP +GS+GP G G PGP G Sbjct: 648 GRQGFPGDFGDRG-PAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGN 706 Query: 889 ----PARGPHPSQGP--------IPFQQQKTPLLG-DGPRAPFNQEGQSTGPPPLIPGLG 935 +G QG P + L G G R GQ TG P L G Sbjct: 707 KGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQ-TGDPGLQGPSG 765 Query: 936 QQGAQGRIPPLN-PGQ-GPGPNKG--DSRGPPNHHMGPMSERRHEQSGGP-----EHGPE 986 G +G + PGQ GP KG +RGPP GP + + GP E GP Sbjct: 766 PPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPP----GPPGLKGTQGEEGPIGAFGELGPR 821 Query: 987 RGPFRGGQDCRGPPDRRGPHPDFPDD-----------FSRPDDFHPDKRFGHRLREFEGR 1035 P G + G P G + D P + G + G Sbjct: 822 GKP--GQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGE--RGS 877 Query: 1036 GGPL-PQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPE-- 1092 GPL PQ EK G PGPP P G ARGPPG+ + P +R R P+ Sbjct: 878 PGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGS---QGPKGQRGSRGPDGL 934 Query: 1093 --DPRFRGRREESFRRGAPPRH-----EGRAPPRGRDGFPGPEDFGPEENFDASEEAARG 1145 + +G + E +G H G RG G PG + P D G Sbjct: 935 LGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGL-PGSTGDRGLPGEPG 993 Query: 1146 RDLRGRGRGTPRGGRKGLLPTP----DEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRP 1201 LRG G G+ P + + E G K D G G R P Sbjct: 994 --LRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRG--EP 1049 Query: 1202 DHPPHDGHSPASRERSSSLQGMDMASLPP--RKRPWHDGPGTSEHREMEAPG--GPSEDR 1257 P +G LQG D P R P DG E EM PG GP Sbjct: 1050 GAPGEEG-----------LQGKDGLKGVPGGRGLPGEDG----EKGEMGLPGIIGPLGRS 1094 Query: 1258 GGKGRGGPGPAQRVP-KSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRG 1316 G G GP +P + GR + G P G G P + G+SG RG Sbjct: 1095 GQTGLPGPEGIVGIPGQRGRPGKKGDKGQIG-----PTGEVGSRGPPGKIGKSGPKGARG 1149 Query: 1317 S 1317 + Sbjct: 1150 T 1150 Score = 167 bits (422), Expect = 8e-41 Identities = 118/341 (34%), Positives = 156/341 (45%), Gaps = 36/341 (10%) Query: 582 LLGPQPFPG----QGPMSQI-PQGFQQPHPSQQMP-MNMAQMGPPGPQGQFRPPGPQGQM 635 L+GP PG +G Q P G P + P + +GPPGP+G+ P G QG+ Sbjct: 1159 LMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGER 1218 Query: 636 GPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGP 695 G G ++G G G G G QGPP G P Q G QG++ G G G +G PGP Sbjct: 1219 GEPGAEGYKGHVGVPGLRGATGQQGPP-GEPGDQ---GEQGLKGERGSEGNKGKKGAPGP 1274 Query: 696 QGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHP 755 G G G G GP G QG+ G G G G +GP G G G++G PG G+ G P P Sbjct: 1275 SGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGP 1334 Query: 756 HGIQGG---PGSQGIQGPVSQGPLMGL-NPRGMQGPPGPRENQGPAPQGMIMGHPPQEMR 811 G++G PGS GIQGP + L G +G +G G + +QGP + G P + Sbjct: 1335 PGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGE--- 1391 Query: 812 GPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGP------- 864 +G Q + G Q G +GP ++G +GP G + GP Sbjct: 1392 ----------YGVQGLTGFQGFPGPKGPEGDAGIVGISGP-KGPIGHRGNTGPLGREGII 1440 Query: 865 -PQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQ 904 P G GP + G +G GPQG + P P P P +Q Sbjct: 1441 GPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQ 1481 Score = 166 bits (421), Expect = 1e-40 Identities = 149/463 (32%), Positives = 188/463 (40%), Gaps = 73/463 (15%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 G PG G+ G G +GP G G GP+G +G G +G P G + GP G Sbjct: 1071 GLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRP-GKKGDKGQIGPTGE 1129 Query: 678 QRHPGPHGPLGPQGPPGPQGSSGPQGH---MGPQGPPGPQGHIGPQGPPGPQGHLGPQGP 734 GP G +G GP G +G+ G GH MGP G PG G+ G QG PGP G GP+G Sbjct: 1130 VGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGE 1189 Query: 735 PGTQG----MQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGP 790 G G + GPPGPRG GP G +G PG++G +G V L G G QGPPG Sbjct: 1190 KGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGAT--GQQGPPGE 1247 Query: 791 RENQGPAPQGMIMGHPPQEMRG----PHPPGGLLGHGPQEMRGPQEIRGMQGPPP---QG 843 +QG QG+ + +G P P G G Q + GP+ I+G G Sbjct: 1248 PGDQGE--QGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNP 1305 Query: 844 SMLGPPQE-----LRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQG 898 +GPP + +RG PG G P GPP G G PG G Q P +G G Sbjct: 1306 GKIGPPGKQGLPGIRGGPGRTGLAGAP----GPPGVKGSSGLPGSPGIQGP-KGEQGLPG 1360 Query: 899 PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQG-PGPNKG 957 Q ++ G + P G P G+ G QG L QG PGP Sbjct: 1361 QPGIQGKRGHRGAQGDQGPCGDPGLKGQP-------GEYGVQG----LTGFQGFPGPKGP 1409 Query: 958 DSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPD 1017 + GP H + GP G + GP R GP + Sbjct: 1410 EGDAGIVGISGPKGPIGHRGNTGP---------LGREGIIGPTGRTGPRGE--------- 1451 Query: 1018 DFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHRE 1060 + F G GP Q + + G PGPP P R+ Sbjct: 1452 ------------KGFRGETGP--QGPRGQPGPPGPPGAPGPRK 1480 >gi|119829187 alpha 1 type XVII collagen [Homo sapiens] Length = 1497 Score = 213 bits (543), Expect = 8e-55 Identities = 189/567 (33%), Positives = 233/567 (41%), Gaps = 112/567 (19%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 G PGP+G PGP+G G G P G GP G GPQGP+G + P M GP G Sbjct: 567 GSPGPKGDMGSPGPKGDRGFPGTP---GIPGPLGHPGPQGPKGQKGSVGDP-GMEGPMGQ 622 Query: 678 QRHPGPHGPLGPQGPP--GPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPP 735 + GP GP G GPP G +G G G GP GPPG G +GP+G G G GP GP Sbjct: 623 RGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPV 682 Query: 736 GTQGMQ---------------GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ-GPLMGL 779 G QG++ GPPGP+G QG P G+ G PG +G+ G V + G + Sbjct: 683 GLQGLRGEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAM 742 Query: 780 NPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGP 839 P G G GPR QG I G PP P PG GPQ + G G++G Sbjct: 743 GPAGPDGHQGPRGEQGLTGMPGIRG-PPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGE 801 Query: 840 P--------PQGSML----GPPQELRGPPGSQSQQGPPQGSLGPPPQGG---------MQ 878 P +GS + GPP GPPG+ GPP G+ GP G +Q Sbjct: 802 PGAPGKIVTSEGSSMLTVPGPP----GPPGAMGPPGPP-GAPGPAGPAGLPGHQEVLNLQ 856 Query: 879 GPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQG 938 GPPGP G + P P PS IP GP P G+ PP PG Sbjct: 857 GPPGPPGPRGP---PGPS---IP-----------GPPGPRGPPGEGLPGPPGPPGSFLSN 899 Query: 939 AQGRI--PPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDC 996 ++ + PP PG PGP KGD +GPP GP R H+ G G G + Sbjct: 900 SETFLSGPPGPPGP-PGP-KGD-QGPP----GP---RGHQGEQGLPGFSTSGSSSFGLNL 949 Query: 997 RGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPP 1056 +GPP GP + D P + GG + G PGPP PP Sbjct: 950 QGPPGPPGPQG------PKGDKGDPGVPGALGIPSGPSEGG--SSSTMYVSGPPGPPGPP 1001 Query: 1057 DHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRA 1116 GPPG+ +++ + + +S R G Sbjct: 1002 ---------------GPPGSISSSGQEIQQYISE-------YMQSDSIRSYL----SGVQ 1035 Query: 1117 PPRGRDGFPGPEDFGPEENFDASEEAA 1143 P G G PGP E FD SE A+ Sbjct: 1036 GPPGPPGPPGPVTTITGETFDYSELAS 1062 Score = 212 bits (539), Expect = 2e-54 Identities = 175/504 (34%), Positives = 211/504 (41%), Gaps = 76/504 (15%) Query: 579 GTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNM-AQMGPPGPQGQFRPPGP------ 631 GTP + P P GP Q P + PM + GP GP+G+ PPG Sbjct: 588 GTPGI-PGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGER 646 Query: 632 --QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGP 689 G+ GP GPP G GP+G G GPQGP P P + G +G PG G GP Sbjct: 647 GAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGP----PGPVGLQGLRGEVGLPGVKGDKGP 702 Query: 690 QGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGM 749 GPPGP+G G +G G G PG +G G G PG +G +GP GP G QG +G G GM Sbjct: 703 MGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGM 762 Query: 750 QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPR-GMQGPPGPR----ENQG------PAP 798 G P G G PG G+ GP L G R G++G PG ++G P P Sbjct: 763 PGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGP 822 Query: 799 QGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGS 858 G PP M P PPG GP + G QE+ +QGPP GPP RGPPG Sbjct: 823 PG-----PPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPP------GPPGP-RGPPG- 869 Query: 859 QSQQGPPQGSLGPPPQGGMQGPPGPQG-----QQNPARGPHPSQGPIPFQQQKTPLLGDG 913 S GPP G GPP + G+ GPPGP G + GP GP P G Sbjct: 870 PSIPGPP-GPRGPPGE-GLPGPPGPPGSFLSNSETFLSGPPGPPGP------PGPKGDQG 921 Query: 914 PRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPG-QGPGPNKGDSRGPPNHHMGPMSE 972 P P +G+ P G G + PP PG QGP +KGD P G + Sbjct: 922 PPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVP-----GAL-- 974 Query: 973 RRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREF 1032 G GP G GPP GP P P S G ++++ Sbjct: 975 -------GIPSGPSEGGSSSTMYVSGPPGPPGP-PGPPGSISSS---------GQEIQQY 1017 Query: 1033 EGRGGPLPQEEKWRRGGPGPPFPP 1056 + G GPP PP Sbjct: 1018 ISEYMQSDSIRSYLSGVQGPPGPP 1041 Score = 175 bits (443), Expect = 3e-43 Identities = 138/374 (36%), Positives = 154/374 (41%), Gaps = 91/374 (24%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 P P GP+ G+ M +P +P MGP GP G P G QG Sbjct: 706 PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAK-------GAMGPAGPDGHQGPRGEQG 758 Query: 634 QMGP---QGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQG------------MQ 678 G +GPP G G G GPQGPQG P G P + G G M Sbjct: 759 LTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLP-GTPGRPGIKGEPGAPGKIVTSEGSSML 817 Query: 679 RHPGPHGPLGPQGPPGPQGSSGPQGH------------MGPQGPPGPQGHIGPQ--GPPG 724 PGP GP G GPPGP G+ GP G GP GPPGP+G GP GPPG Sbjct: 818 TVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPG 877 Query: 725 P-----QGHLGPQGPPGT------------QGMQGPPGPRGMQGPPHPHGIQGGPGSQGI 767 P +G GP GPPG+ G GPPGP+G QGPP P G QG G G Sbjct: 878 PRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGF 937 Query: 768 QGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGL-LGHGPQE 826 S GLN +QGPPGP P PQG P + P PG L + GP E Sbjct: 938 S--TSGSSSFGLN---LQGPPGP-----PGPQG-----PKGDKGDPGVPGALGIPSGPSE 982 Query: 827 --MRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP---------QGSLGPPPQG 875 + G GPP GPP GPPGS S G Q Sbjct: 983 GGSSSTMYVSGPPGPP------GPP----GPPGSISSSGQEIQQYISEYMQSDSIRSYLS 1032 Query: 876 GMQGPPGPQGQQNP 889 G+QGPPGP G P Sbjct: 1033 GVQGPPGPPGPPGP 1046 Score = 111 bits (277), Expect = 5e-24 Identities = 175/592 (29%), Positives = 206/592 (34%), Gaps = 159/592 (26%) Query: 732 QGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPR 791 +G PG +G G PGP+G +G P GI G G G QGP Q +G GM+GP G R Sbjct: 566 RGSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVG--DPGMEGPMGQR 623 Query: 792 ENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQE 851 +GP GP G G G + RG G GPP +GP Sbjct: 624 GREGPM--------------GPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGP--- 666 Query: 852 LRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLG 911 +G GS QGPP G +G G G PG +G + P P GP Q +K Sbjct: 667 -KGSSGSPGPQGPP-GPVGLQGLRGEVGLPGVKGDKGPMGPP----GPKGDQGEK----- 715 Query: 912 DGPRAPFNQEGQSTGPPPL--IPG-LGQQGAQGRIPPLNPG--QGPGPNKGDS-----RG 961 GPR TG P + +PG +G+ GA+G + P P QGP +G + RG Sbjct: 716 -GPRG-------LTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRG 767 Query: 962 PPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRG--PHPDFPDDFSRPDDF 1019 PP GP SG P GP +G Q G P R G P P Sbjct: 768 PP----GP--------SGDPGKPGLTGP-QGPQGLPGTPGRPGIKGEPGAP--------- 805 Query: 1020 HPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEG 1079 G + E PGPP PP G GPPGA Sbjct: 806 ----------------GKIVTSEGSSMLTVPGPPGPP---------GAMGPPGPPGA--- 837 Query: 1080 RRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDAS 1139 PG P P +E PP P G G PGP GP Sbjct: 838 --PG-------PAGPAGLPGHQEVLNLQGPPG------PPGPRGPPGPSIPGPP------ 876 Query: 1140 EEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTP 1199 RG G G P G L + F G P PGP + P Sbjct: 877 --GPRGPP--GEGLPGPPGPPGSFLSNSETF--LSGPPGPPG-----PPGPKGDQGPPGP 925 Query: 1200 RPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGG 1259 R H G S SSS G+++ P GP P GP D+G Sbjct: 926 R-GHQGEQGLPGFSTSGSSSF-GLNLQGPP--------GP--------PGPQGPKGDKGD 967 Query: 1260 KGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG-SGTPSRGGRSG 1310 G G P G SSS Y P GPPG G P SG Sbjct: 968 PGVPGALGIPSGPSEGGSSS------TMYVSGPP--GPPGPPGPPGSISSSG 1011 Score = 99.0 bits (245), Expect = 3e-20 Identities = 109/382 (28%), Positives = 141/382 (36%), Gaps = 93/382 (24%) Query: 584 GPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLH 643 GP G G + + M + +G PGP G PPG G + L Sbjct: 1112 GPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPG---PPGLPGTSYEELLSLL 1168 Query: 644 QGGGGPQGFMGPQGPQGPPQGLP-------RPQDMHG---PQGMQRHPGPHGPLGPQGPP 693 +G +G +GP GP GPP G+P +D+ G+ PGP GP GP GP Sbjct: 1169 RGSEF-RGIVGPPGPPGPP-GIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPR 1226 Query: 694 GPQGSSGPQGHMGPQGPPGPQGHI-----GPQ------GPPGPQGHLGPQGPPGTQGMQG 742 GP G SG + + + P GPPGP GPQGPPG + Sbjct: 1227 GPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPP---GPQGPPGDSRLLS 1283 Query: 743 PPG--PRGMQGPPHPHGIQ-------------GGPGSQGIQGPVSQGPLMGLNPRGMQGP 787 RG H ++ GG GS G G + RG G Sbjct: 1284 TDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGE----AAGDRGPYGT 1339 Query: 788 P-GPRENQGPAPQ-GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQE-----IRGMQGPP 840 GP G A + GM G+ GGLLG + G + +R + Sbjct: 1340 DIGPGGGYGAAAEGGMYAGN-----------GGLLG---ADFAGDLDYNELAVRVSESMQ 1385 Query: 841 PQGSMLGPPQELRGPPGSQSQQGPP----------------------QGSL-GPPPQGGM 877 QG + G ++GPPG QGPP G++ GPP Q G Sbjct: 1386 RQGLLQGMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGE 1445 Query: 878 QGPPGPQGQQNPARGPHPSQGP 899 G PGP+G + PA GP GP Sbjct: 1446 MGTPGPKGDRGPA-GPPGHPGP 1466 Score = 79.3 bits (194), Expect = 2e-14 Identities = 122/449 (27%), Positives = 148/449 (32%), Gaps = 161/449 (35%) Query: 617 MGPPGPQGQFRPPGPQG----------QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLP 666 MGP GP G PPG G ++ + G G GP GP G P G Sbjct: 1105 MGPRGPPG---PPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLP-GTS 1160 Query: 667 RPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSG----------------PQGHMGPQGP 710 + + +G + G +GP GPPGP G G G GP Sbjct: 1161 YEELLSLLRGSEFR----GIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGP 1216 Query: 711 PGPQGHIGPQGPPGPQGHLGPQ--------------------------GPPGTQGMQGPP 744 PGP G GP+GPPG G L GPPG G QGPP Sbjct: 1217 PGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPP 1276 Query: 745 GP-----------RGMQGPPHPHGIQ-------------GGPGSQGIQGPVSQGPLMGLN 780 G RG H ++ GG GS G G + Sbjct: 1277 GDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSSSMSTGGGGAGSLGAGGAFGEAA----G 1332 Query: 781 PRGMQGPP-GPRENQGPAPQG-MIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQE-----I 833 RG G GP G A +G M G+ GGLLG + G + + Sbjct: 1333 DRGPYGTDIGPGGGYGAAAEGGMYAGN-----------GGLLG---ADFAGDLDYNELAV 1378 Query: 834 RGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGP 893 R + QG + G ++GPPG Q G QGPPG Sbjct: 1379 RVSESMQRQGLLQGMAYTVQGPPG----------------QPGPQGPPGI---------- 1412 Query: 894 HPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPG 953 S+ + L+ F G GPP GQ+G G PG Sbjct: 1413 --SKVFSAYSNVTADLMDF-----FQTYGAIQGPP------GQKGEMGT---------PG 1450 Query: 954 PNKGDSRGP--PNHHMGPMSERRHEQSGG 980 P KGD RGP P H GP R H+ G Sbjct: 1451 P-KGD-RGPAGPPGHPGPPGPRGHKGEKG 1477 Score = 63.2 bits (152), Expect = 2e-09 Identities = 50/154 (32%), Positives = 61/154 (39%), Gaps = 21/154 (13%) Query: 633 GQMGPQGPPLHQGGG-GPQGFMGPQGPQGPPQGLPRPQDM-------HGPQGMQRH---- 680 G GP G + GGG G G G G D+ + MQR Sbjct: 1332 GDRGPYGTDIGPGGGYGAAAEGGMYAGNGGLLGADFAGDLDYNELAVRVSESMQRQGLLQ 1391 Query: 681 ------PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP 734 GP G GPQGPPG ++ Q + QGPPG +G +G GP Sbjct: 1392 GMAYTVQGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGP 1451 Query: 735 PGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQ 768 G +G GPPG GPP P G +G G +G Q Sbjct: 1452 KGDRGPAGPPG---HPGPPGPRGHKGEKGDKGDQ 1482 Score = 63.2 bits (152), Expect = 2e-09 Identities = 35/88 (39%), Positives = 42/88 (47%), Gaps = 5/88 (5%) Query: 648 GPQGFMGPQGPQGPPQGLPRPQDMHGP-----QGMQRHPGPHGPLGPQGPPGPQGSSGPQ 702 GP G GPQGP G + ++ Q GP G G G PGP+G GP Sbjct: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA 1458 Query: 703 GHMGPQGPPGPQGHIGPQGPPGPQGHLG 730 G G GPPGP+GH G +G G Q + G Sbjct: 1459 GPPGHPGPPGPRGHKGEKGDKGDQVYAG 1486 Score = 62.8 bits (151), Expect = 2e-09 Identities = 38/95 (40%), Positives = 48/95 (50%), Gaps = 8/95 (8%) Query: 650 QGFMGPQGPQGPPQGLPRPQDMHG--PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGP 707 QG G GPQGPP G+ + + + +G + QGPPG +G G G G Sbjct: 1398 QGPPGQPGPQGPP-GISKVFSAYSNVTADLMDFFQTYGAI--QGPPGQKGEMGTPGPKGD 1454 Query: 708 QGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQG 742 +GP GP GH GPPGP+GH G +G G Q G Sbjct: 1455 RGPAGPPGH---PGPPGPRGHKGEKGDKGDQVYAG 1486 Score = 57.4 bits (137), Expect = 9e-08 Identities = 37/106 (34%), Positives = 51/106 (48%), Gaps = 9/106 (8%) Query: 557 EQLKIERLAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQ--MPMNM 614 E ++ + L Q +Q PP G P GPQ PG +S++ + Sbjct: 1382 ESMQRQGLLQGMAYTVQGPP--GQP--GPQGPPG---ISKVFSAYSNVTADLMDFFQTYG 1434 Query: 615 AQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQG 660 A GPPG +G+ PGP+G GP GPP H G GP+G G +G +G Sbjct: 1435 AIQGPPGQKGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480 Score = 53.5 bits (127), Expect = 1e-06 Identities = 90/341 (26%), Positives = 113/341 (33%), Gaps = 60/341 (17%) Query: 1036 GGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPR 1095 G P P+ ++ G PG P P H G+ + G PG EG P +R P PR Sbjct: 576 GSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGM-EG--PMGQRGREGPMGPR 632 Query: 1096 FRGRREESFRRG-----------APPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAAR 1144 S +G PP G P+G G PGP+ GP + R Sbjct: 633 GEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQ--GPPG--PVGLQGLR 688 Query: 1145 GR----DLRG-------------RGRGTPRG--GRKGL--LPTPDEFPRFEGGRKPDSWD 1183 G ++G +G PRG G G+ LP P +G P D Sbjct: 689 GEVGLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPD 748 Query: 1184 GNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRK--RPWHDGPG- 1240 G++ P G + P PP P + + P R + PG Sbjct: 749 GHQGPR-GEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGK 807 Query: 1241 --TSEHREMEAPGGPSEDRGGKGR----GGPGPAQRVPKSGRSSSLDGEHHDGYHRDE-- 1292 TSE M GP G G G PGPA G L+ + G Sbjct: 808 IVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGP 867 Query: 1293 -------PFG--GPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324 P G GPPG G P G GS SGPP Sbjct: 868 PGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPP 908 Score = 41.6 bits (96), Expect = 0.005 Identities = 25/68 (36%), Positives = 28/68 (41%), Gaps = 25/68 (36%) Query: 630 GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGP 689 GP GQ G G P GP+G GP GP G HPGP GP G Sbjct: 1438 GPPGQKGEMGTP------GPKGDRGPAGPPG-------------------HPGPPGPRGH 1472 Query: 690 QGPPGPQG 697 +G G +G Sbjct: 1473 KGEKGDKG 1480 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 210 bits (535), Expect = 6e-54 Identities = 242/836 (28%), Positives = 291/836 (34%), Gaps = 145/836 (17%) Query: 583 LGPQPFPGQGPMS--QIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRP------PGPQGQ 634 LG PG+ M Q P G P P + G G +G+ PG G Sbjct: 556 LGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGD 615 Query: 635 MGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPG 694 G QG P G GPQG G GP GPP G +G Q PGP G G GPPG Sbjct: 616 TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675 Query: 695 PQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPH 754 +G GP+G GP G G +G G GPPG G LG QGPPG G+ GPPGP G G P Sbjct: 676 ARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPG 735 Query: 755 PHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPH 814 G G PG G GP + P G GPPG + G + + G P Sbjct: 736 EIGFPGKPGPPGPTGPPGKD-----GPNGPPGPPGTKGEPGERGEDGLPGKP-------- 782 Query: 815 PPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQ 874 GL G G Q + G G + + G P G PG + ++G QG G Sbjct: 783 ---GLRGE-----IGEQGLAGRPGEKGEAGLPGAP----GFPGVRGEKG-DQGEKGELGL 829 Query: 875 GGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPG- 933 G++G G +G+ PA GP P T L PR P Q + P +PG Sbjct: 830 PGLKGDRGEKGEAGPA-GP-------PGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE 881 Query: 934 LGQQGAQGRIPPLNPGQGPG----------PNKGDSRGPPNH------HMGPMSERRHEQ 977 G QG G + P P PG P + G P H P S Sbjct: 882 PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGL 941 Query: 978 SGGPEHGPERGPFRGGQDCRGPPDRRGPH-----PDFPDDFSRPDDFHPDKRFGHRLREF 1032 G P ERG +G G P GP P P + D P LR Sbjct: 942 RGTPGKDGERGE-KGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPG------LRGS 994 Query: 1033 EGRGGPL------------------PQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPP 1074 G GPL Q K RG PG P P S GD GPP Sbjct: 995 PGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG----SRGDPGIGVAGPP 1050 Query: 1075 GAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAP----------------- 1117 G PGD+ P P F G + + R GAP R P Sbjct: 1051 G--PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINL 1108 Query: 1118 ---------PRGRDGFPGPEDFGPEENFDA--SEEAARGRDLRGRGRGTPRGGRKGLLPT 1166 P G G PG F ++ E G+ +G P G LP Sbjct: 1109 LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGK----KGEAGPPG-----LPG 1159 Query: 1167 PDEFPRFEGGRKPDSWDG-----NREPGPGHEHFRDTP-RPDHPPHDGHSPASRERSSSL 1220 P +G + DG + PG F P P P DG + A+ + Sbjct: 1160 PPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA--GPPGI 1217 Query: 1221 QGMDMASLPPRKRPWHDGPGTSEHREMEA----PGGPSEDRGGKGRGGPGP-AQRVPKSG 1275 QG PP + PG E PG P E G PGP R P Sbjct: 1218 QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 1277 Query: 1276 RSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 + + D G P G P + G +G +G GPP + S G Sbjct: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 1333 Score = 195 bits (496), Expect = 2e-49 Identities = 200/643 (31%), Positives = 242/643 (37%), Gaps = 158/643 (24%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFR------ 627 PP SG P G + PG + P G Q P P N + GPPG G Sbjct: 1049 PPGPSGPP--GDKGSPGSRGLPGFP-GPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGD 1105 Query: 628 ------------PPGP---------QGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLP 666 PPGP +G G G P +G G +G GP G GPP G+ Sbjct: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP-GIA 1164 Query: 667 RPQDMHGPQGM---------QRHPGPHGPLGPQGPPGPQGSSGPQGHMGP---------Q 708 PQ G +G Q HPG G +GP G PGP G+ G G GP + Sbjct: 1165 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224 Query: 709 GPPGPQGHIGPQGPPGPQGHLG------PQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGP 762 GPPGPQG G G PG +G G P G PG G G PGP G +GPP G +G Sbjct: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPP---GFKGHT 1281 Query: 763 GSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPA-PQGMIMGHPPQEMRGPHPPGGLLG 821 G G GP + MGL G +G PG + GP PQG PQ RGP G G Sbjct: 1282 GDSGAPGPRGESGAMGLP--GQEGLPGKDGDTGPTGPQG------PQGPRGPPGKNGSPG 1333 Query: 822 H----GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP-----QGSLGPP 872 GP G + +G G P LGP RGPPG ++G P G G P Sbjct: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGP----RGPPGEPGEKGVPGKEGVPGKPGEP 1389 Query: 873 PQGGMQGPPGPQGQQNPARGP-HPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLI 931 G +G PG +G + P G P IP + T L+G N GPP Sbjct: 1390 GFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPP--- 1446 Query: 932 PGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERR-----------HEQSGG 980 GQ G G +G P+ R +G E R + +S Sbjct: 1447 ---GQPGFPGL-------RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQ 1496 Query: 981 PEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPL- 1039 GP P G+D G P R GP + RP EG GP+ Sbjct: 1497 GRPGPPGPP---GKD--GLPGRAGPM----GEPGRPGQ-----------GGLEGPSGPIG 1536 Query: 1040 PQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGR 1099 P+ E+ +G PG P G G GPPG P P +P + Sbjct: 1537 PKGERGAKGDPGAP----------GVGLRGEMGPPG-----------IPGQPGEPGYA-- 1573 Query: 1100 REESFRRGAP--PRHEGRAPPRGRDGFPGPEDFGPEENFDASE 1140 + G P P +G P G G PGP GP D S+ Sbjct: 1574 -----KDGLPGIPGPQGETGPAGHPGLPGPP--GPPGQCDPSQ 1609 Score = 195 bits (495), Expect = 3e-49 Identities = 247/809 (30%), Positives = 301/809 (37%), Gaps = 154/809 (19%) Query: 569 VEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRP 628 V + PPP P P PG + GF + +MG GP G P Sbjct: 448 VTEPPPPPPPQRP-----PTPGSEQI-----GFLKTINCSCPAGEKGEMGVAGPMGLPGP 497 Query: 629 PGPQGQMGPQGPPLHQGGGGPQGFMGP--QGPQGPPQ--GLPRPQDMHGPQGMQRHPGPH 684 G G +GP G P +G G G +GP QG +G GLP P G +GM+ PG Sbjct: 498 KGDIGAIGPVGAPGPKGEKGDVG-IGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL 556 Query: 685 GPLGPQGPPGPQGSSGPQGHMGPQ---GPPGPQGHIGPQGPPGPQGHLGPQ---GPPGTQ 738 G G G G +G GP G GP G PG QG G +G G +G G G PG Sbjct: 557 GEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDT 616 Query: 739 GMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG-PA 797 G QG PGP G+ GP G G G G+ G V Q GL +G QG PGPR +QG P Sbjct: 617 GQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQE--GL--KGEQGAPGPRGHQGAPG 672 Query: 798 PQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPG 857 P G RGP P G GP ++G + +G GPP +LG L+GPPG Sbjct: 673 PPG---------ARGPIGPEG--RDGPPGLQGLRGKKGDMGPPGIPGLLG----LQGPPG 717 Query: 858 SQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPR 915 GP P GS G P + G G PGP G P P+ P P + P G R Sbjct: 718 PPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEP----GER 773 Query: 916 APFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRH 975 E G P L +G+QG GR PG+ + G P + Sbjct: 774 G----EDGLPGKPGLRGEIGEQGLAGR-----PGEKGEAGLPGAPGFPGVRGEKGDQGEK 824 Query: 976 EQSGGPEHGPERGPFRGGQDCRGPPDRRG------PHPDFPDDFSRPDDFHPDKRFGHRL 1029 + G P +RG +G GPP G PHP P + + G Sbjct: 825 GELGLPGLKGDRGE-KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE-- 881 Query: 1030 REFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGA-WEGRRPGDERFP 1088 +GR G L G GP PP + G A G PGA PG P Sbjct: 882 PGLQGRPGEL--------GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPP 933 Query: 1089 RDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDA---SEEAARG 1145 P RG + RG +G A G +G PGP GP + A +G Sbjct: 934 GSVGAPGLRGTPGKDGERG----EKGAA---GEEGSPGP--VGPRGDPGAPGLPGPPGKG 984 Query: 1146 RDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRK-----------------PDSWDGNREP 1188 +D RG+P G G L T + G P S +P Sbjct: 985 KDGEPGLRGSP--GLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDP 1042 Query: 1189 GPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREME 1248 G G P P PP D SP SR L G P GP + Sbjct: 1043 GIG---VAGPPGPSGPPGDKGSPGSR----GLPGF----------PGPQGPAGRD----G 1081 Query: 1249 APGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG--------- 1299 APG P E RG PG K G SS L + +D PPG Sbjct: 1082 APGNPGE------RGPPG------KPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPG 1129 Query: 1300 ----SGTPSRGGRSGSNWGRGSNMNSGPP 1324 G P + GR G+ +G +GPP Sbjct: 1130 FKGDKGVPGKPGREGTEGKKG---EAGPP 1155 Score = 190 bits (482), Expect = 9e-48 Identities = 248/866 (28%), Positives = 318/866 (36%), Gaps = 189/866 (21%) Query: 556 LEQLKIERLAQKQVEQIQPPPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNM 614 L LK +R + + PP GT L P P + P Q P+G + P Sbjct: 829 LPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHP---RMPGEQGPKGEKGDPGLPGEPGLQ 885 Query: 615 AQMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP--------QGLP 666 + G GPQG PPG +GQ G G P G G G +G GP GPP +G P Sbjct: 886 GRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTP 945 Query: 667 RPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGH--------MGPQGPPGPQGH-- 716 G +G G GP+GP+G PG G GP G G G PGP G Sbjct: 946 GKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKA 1005 Query: 717 --------------------------------------IGPQGPPGPQGHLGPQGPPGTQ 738 IG GPPGP G G +G PG++ Sbjct: 1006 ACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSR 1065 Query: 739 GMQG---PPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGL----------NPRGMQ 785 G+ G P GP G G P G +G PG G+ +S G + L P G+ Sbjct: 1066 GLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLP 1125 Query: 786 GPPGPRENQGPAPQGMIMGHPPQE----MRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPP 841 G PG + ++G + G P +E +G P GL GP + GPQ +G +G Sbjct: 1126 GLPGFKGDKG------VPGKPGREGTEGKKGEAGPPGL--PGPPGIAGPQGSQGERGADG 1177 Query: 842 QGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQG-QQNPAR-GPHPSQGP 899 + G +G PG GPP G+ GPP G+ G GP G Q +P + GP QGP Sbjct: 1178 EVGQKGD----QGHPGVPGFMGPP-GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGP 1232 Query: 900 -----IPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGL-GQQGAQGRIPPLNPGQGPG 953 IP ++ K DG P + G++ P GL G +GA+G PP G Sbjct: 1233 SGLPGIPGEEGKEGR--DGKPGPPGEPGKAGEP-----GLPGPEGARG--PPGFKG---- 1279 Query: 954 PNKGDSRGP-PNHHMGPMSERRHEQSGGPEHGPERGPF--RGGQDCRGPPDRRGPHPDFP 1010 + GDS P P G M Q G P + GP +G Q RGPP + G Sbjct: 1280 -HTGDSGAPGPRGESGAMG--LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP---- 1332 Query: 1011 DDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAA 1070 P + P G P + K G PG P G Sbjct: 1333 ---GSPGEPGPS-------------GTPGQKGSKGENGSPGLP------------GFLGP 1364 Query: 1071 RGPPGA-WEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPP--------RGR 1121 RGPPG E PG E P P +P F+G R + +G G+ P +G Sbjct: 1365 RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 1424 Query: 1122 DGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDS 1181 G GP+ P EN G+ G P G +G P+ + R Sbjct: 1425 TGLMGPQGL-PGENGPVGPPGPPGQP------GFP--GLRGESPSMETLRRLI------- 1468 Query: 1182 WDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGT 1241 E G E PP S R G D LP R P + PG Sbjct: 1469 ---QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKD--GLPGRAGPMGE-PGR 1522 Query: 1242 SEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSS--SLDGEHHD-GYHRDEPFGGPP 1298 +E P GP +G +G G A V G + G+ + GY +D G P Sbjct: 1523 PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD----GLP 1578 Query: 1299 GSGTPSRGGRSGSNWGRGSNMNSGPP 1324 G P G +G G GPP Sbjct: 1579 --GIPGPQGETGPAGHPGLPGPPGPP 1602 Score = 184 bits (468), Expect = 4e-46 Identities = 166/485 (34%), Positives = 204/485 (42%), Gaps = 90/485 (18%) Query: 562 ERLAQKQVEQIQPPPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPP 620 ER A +V Q G P +GP PG P + G P Q P + GPP Sbjct: 1172 ERGADGEVGQKGDQGHPGVPGFMGPPGNPGP-PGADGIAGAAGPPGIQGSP---GKEGPP 1227 Query: 621 GPQGQFRPPGPQGQMGPQG------PPLHQGGGGPQGFMGPQGPQGPP------------ 662 GPQG PG G+ G +G PP G G G GP+G +GPP Sbjct: 1228 GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAP 1287 Query: 663 --------QGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQ 714 GLP + + G G GP GP GP+GPPG GS G G GP G PG + Sbjct: 1288 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQK 1347 Query: 715 GHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQG 774 G G G PG G LGP+GPPG G +G PG G+ G P G +G G GI+G +G Sbjct: 1348 GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKG--DKG 1405 Query: 775 PLMGLNPRGMQGPPGPRENQG-PAPQGMIMGHPPQEMRGPHPPG-----GLLGHGPQE-- 826 P G G G PG + + G PQG+ + P + P PPG GL G P Sbjct: 1406 PPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP--VGPPGPPGQPGFPGLRGESPSMET 1463 Query: 827 -MRGPQEIRGMQGPPPQGSMLG--PPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGP 883 R QE G Q +L PP ++ SQ + GPP GPP + G+ G GP Sbjct: 1464 LRRLIQEELGKQLETRLAYLLAQMPPAYMK---SSQGRPGPP----GPPGKDGLPGRAGP 1516 Query: 884 QGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ-STGPPPLIPGLGQQGAQGR 942 G+ P R P QG + +GP P +G+ P PG+G +G G Sbjct: 1517 MGE--PGR---PGQGGL-----------EGPSGPIGPKGERGAKGDPGAPGVGLRGEMG- 1559 Query: 943 IPPLNPGQ--GPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPP 1000 PP PGQ PG K G P GP E +G H GP GPP Sbjct: 1560 -PPGIPGQPGEPGYAKDGLPGIP----GPQGE-----TGPAGHPGLPGP-------PGPP 1602 Query: 1001 DRRGP 1005 + P Sbjct: 1603 GQCDP 1607 Score = 117 bits (294), Expect = 6e-26 Identities = 177/654 (27%), Positives = 221/654 (33%), Gaps = 129/654 (19%) Query: 731 PQGPPGTQGMQGPPGPRGMQGPPHPHGIQ-------------GGPGSQGIQGPVS----Q 773 P GP + PP P Q PP P Q G G G+ GP+ + Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498 Query: 774 GPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPG-----GLLGH----GP 824 G + + P G GP G + + G P G + P PPG G+ G G Sbjct: 499 GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558 Query: 825 QEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQ 884 + G +RG QGPP + GPP + G PG Q ++G +G+ G + G+ G PG Sbjct: 559 PGLPGEVGMRGPQGPP---GLPGPPGRV-GAPGLQGERG-EKGTRGEKGERGLDGFPGKP 613 Query: 885 GQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGP--PPLIPGL-----GQQ 937 G P PS G P ++G GP PP +PG G + Sbjct: 614 GDTGQQGRPGPS----------------GVAGPQGEKG-DVGPAGPPGVPGSVVQQEGLK 656 Query: 938 GAQGRIPPLNPGQGPGPNKGDSRGP--PNHHMGPMSERRHEQSGGPEHGPERGPFRGGQD 995 G QG P PGP +RGP P GP + G P G Q Sbjct: 657 GEQGAPGPRGHQGAPGP--PGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQG 714 Query: 996 CRGPPDRRGP-----HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGP 1050 GPP GP P P + F G+ GP P Sbjct: 715 PPGPPGVPGPPGPGGSPGLPGEIG-----------------FPGKPGP-----------P 746 Query: 1051 GPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPP 1110 GP PP DG GPPG PG+ P P RG E G P Sbjct: 747 GPTGPPGK------DGPNGPPGPPGT--KGEPGERGEDGLPGKPGLRGEIGEQGLAGR-P 797 Query: 1111 RHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARG-----RDLRGRGRGTPRG--GRKGL 1163 +G A G GFPG E D E+ G D +G P G G G Sbjct: 798 GEKGEAGLPGAPGFPGVRG----EKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT 853 Query: 1164 LPTPDEFPRFEGGRKPDSWDGNREPG-PGHEHFRDTPRPDHPPHDGHSPASRERSSSLQG 1222 PR G + P G +PG PG + P + P P + G Sbjct: 854 TSLFTPHPRMPGEQGPKGEKG--DPGLPGEPGLQGRP-GELGPQGPTGPPGAKGQEGAHG 910 Query: 1223 MDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKG-RGGPGPAQRVPKSGRSSSLD 1281 A+ PG H P GP G G RG PG + G + + Sbjct: 911 APGAA---------GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE-E 960 Query: 1282 GEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRG 1335 G R +P G PG P G+ G RGS GP A+ G RG Sbjct: 961 GSPGPVGPRGDP--GAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRG 1012 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 206 bits (525), Expect = 9e-53 Identities = 245/816 (30%), Positives = 307/816 (37%), Gaps = 136/816 (16%) Query: 616 QMGPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQ 675 + G PG QG PG QG GPQGPP +G G G G +G +GPP P G Sbjct: 50 ERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP----GNP 105 Query: 676 GMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQ-------GH 728 G+ PG GP GP G PG G+ G +G +GP G PG G+ GP G PG + GH Sbjct: 106 GLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGH 165 Query: 729 L------GPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPR 782 + G +G PG G GPPG G+QGP P G G PG G GP + MGL+ Sbjct: 166 VPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLS-- 223 Query: 783 GMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQ 842 QGP G + +QG + + G + +G G G +G +GM G + Sbjct: 224 -FQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKG-----QKGEPGFQGMPGVGEK 277 Query: 843 GSMLGP-PQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHP-----S 896 G P P+ G G + ++G P G G P G+ G GPQG++ A P P Sbjct: 278 GEPGKPGPRGKPGKDGDKGEKGSP-GFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIG 336 Query: 897 QGPIPFQQQKTPLLGDGPRAPFNQEGQSTGP----PPLIPGLGQQGAQGRIPPLNPGQGP 952 GP+ + ++ GPR +G P PP +P GQ GA G G Sbjct: 337 TGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPG-------FPGE 389 Query: 953 GPNKGDSRGPPNHHMGPMS-ERRHEQSGGPEHGPERGPFRGGQDCR-GPPDRRGPHPDFP 1010 KGD P GP + G P + G G +C+ GPP +GP P P Sbjct: 390 RGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGP-PGIP 448 Query: 1011 DDFSRPDDFHPDKRFGHR--LREFEG-RGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGR 1067 + + G + + +G RG P PQ G PG P R DG Sbjct: 449 GQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGV 508 Query: 1068 GAARGPPGA-------WEGRRPG----DERFPRDPEDPRFRGRREESFRRGAPPR--HEG 1114 GP G PG D R D DP F G+ + R G+P R H G Sbjct: 509 AGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPG 568 Query: 1115 ----------------RAPP--------RGRDGFPGPEDFGPEENFDASEEAARGRDLRG 1150 R PP RG G PGP +GP +A Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGS 628 Query: 1151 RGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGP-GHEHFRDTP-RPDHPPHDG 1208 G P+G ++P P P EG + PGP G F TP RP P G Sbjct: 629 PGLPGPKGEPGKIVPLPGP-PGAEGLPGSPGF-----PGPQGDRGFPGTPGRPGLPGEKG 682 Query: 1209 ---------HSPASRERSSSLQGMDMASLPPRKRPWHDG----PGTSEHREMEAPGGPSE 1255 P + L G DM RP +G PG + G P Sbjct: 683 AVGQPGIGFPGPPGPKGVDGLPG-DMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLP-- 739 Query: 1256 DRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYH-----------RDEPFGGPPG----- 1299 G KG G P G S+ G H R EP GPPG Sbjct: 740 --GLKGLPGLPGIPGTP--GEKGSIGVPGVPGEHGAIGPPGLQGIRGEP--GPPGLPGSV 793 Query: 1300 --SGTPSRG--GRSGSNWGRGSNMNSGPPRRGASRG 1331 G P G G G G+G SGPP +G Sbjct: 794 GSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKG 829 Score = 191 bits (486), Expect = 3e-48 Identities = 255/841 (30%), Positives = 305/841 (36%), Gaps = 143/841 (17%) Query: 582 LLGPQPFPG-QGPMS-QIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQG 639 L G FPG QGP Q P G + +P GPPG G PG G G G Sbjct: 56 LQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDG 115 Query: 640 PPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPL------------ 687 PP G G G G +GP GPP GLP GP G+ G G + Sbjct: 116 PPGPPGIPGCNGTKGERGPLGPP-GLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGE 174 Query: 688 ----GPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHL-----GPQGPPGTQ 738 G G PGP G G QG +GP G GP G GP GPPG +G + GP+G G Q Sbjct: 175 RGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQ 234 Query: 739 GMQGPPG--------PRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGP 790 G+ GPPG +G G +G PG QG+ G +G PRG G G Sbjct: 235 GVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGD 294 Query: 791 RENQG-------PAPQGMIMGHPPQEMRG----PHPPGGLLGHGPQEMRGPQEIRGMQGP 839 + +G P G+I PQ +G P PPG ++G GP +G RG G Sbjct: 295 KGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGE---RGYPGT 351 Query: 840 PPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGP 899 P GP +G PG Q GPP L P Q G G PG +G++ P S Sbjct: 352 PGPRGEPGP----KGFPGLPGQPGPP--GLPVPGQAGAPGFPGERGEKGDRGFPGTS--- 402 Query: 900 IPFQQQKTPLLG-DGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQ-------G 951 +P + L G G P Q G + G P G G QG PP PGQ G Sbjct: 403 LPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQP--GPPGDQG--PPGIPGQPGFIGEIG 458 Query: 952 PGPNKGDS---------RGPPNHHMGPMSERRHEQSG--GPEHGPERGPFRGGQDCRGPP 1000 KG+S RGPP P Q G G P R G +G P Sbjct: 459 EKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTP 518 Query: 1001 DRRGPHPDFPDDFSRPDDFHPDKRFGHRLRE--FEGRGG----------------PLPQE 1042 G P P +F+ D R + F G+ G P P+ Sbjct: 519 GLIGQ----PGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKG 574 Query: 1043 EKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDE---RFPRDPEDPRFRGR 1099 G G PP F G GPPG GD+ FP P P G Sbjct: 575 SPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGP 634 Query: 1100 REESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGG 1159 + E + P G G GFPGP+ D GR G P G Sbjct: 635 KGEPGKIVPLPGPPGAEGLPGSPGFPGPQG-------DRGFPGTPGRP------GLP--G 679 Query: 1160 RKGLLPTPD-EFPRFEGGRKPDSWDGNREP--GPGHEHFRDTPRPDHPPHDGHSPASRER 1216 KG + P FP G + D G+ P PG F P +P G Sbjct: 680 EKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGL--PGNPGVQGQKGEPGVG 737 Query: 1217 SSSLQGMDMASLPPRKRPWHDGPGT-SEHREMEAPGGPSEDRGGKG-------RGGPGPA 1268 L+G + LP PGT E + PG P E G G RG PGP Sbjct: 738 LPGLKG--LPGLP-------GIPGTPGEKGSIGVPGVPGE-HGAIGPPGLQGIRGEPGP- 786 Query: 1269 QRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG-SGTPSRGGRSGSNWGRGSNMNSGPPRRG 1327 +P S S + G G GPPG SG P G G G +M +G Sbjct: 787 PGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG 846 Query: 1328 A 1328 A Sbjct: 847 A 847 Score = 187 bits (476), Expect = 4e-47 Identities = 245/809 (30%), Positives = 307/809 (37%), Gaps = 118/809 (14%) Query: 575 PPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 P G P L GP+ PG + +G + P P + GPPGP G + P GP G Sbjct: 561 PGRDGHPGLPGPKGSPGSVGL----KGERGPPGGVGFPGSRGDTGPPGPPG-YGPAGPIG 615 Query: 634 QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPP 693 G G P GG G G GP+G G LP P G G PGP G G G P Sbjct: 616 DKGQAGFP---GGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTP 672 Query: 694 GPQGSSGPQGHMGPQG-----PPGPQG------HIGPQGPPGPQGHLGPQGPPGTQGMQG 742 G G G +G +G G PPGP+G +GP G PG G G G PG QG +G Sbjct: 673 GRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKG 732 Query: 743 PPGPR--GMQGPPHPHGIQGGPGSQGIQG----PVSQGPLMGLNPRGMQGPPGPRENQGP 796 PG G++G P GI G PG +G G P G + +G++G PGP G Sbjct: 733 EPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGS 792 Query: 797 APQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPP 856 + G P RGP PGG GP + GP I+G +G P P ++ GP Sbjct: 793 VGSPGVPGIGPPGARGP--PGG---QGPPGLSGPPGIKGEKGFPGF-----PGLDMPGPK 842 Query: 857 GSQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRA 916 G + QG P G Q G+ G PG QG P P + + ++G Sbjct: 843 GDKGAQGLP----GITGQSGLPGLPGQQGA--------PGIPGFPGSKGEMGVMGT---- 886 Query: 917 PFNQEGQSTGPPPL-IPGL-GQQGAQGRIPPLNPGQGPG--PNKGDSR--GPPNH----H 966 GQ P P+ PGL G++G G P PG +KGD G P Sbjct: 887 ----PGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVD 942 Query: 967 MGPMSERRHEQSGGPEHGP--ERG----------PFRGGQDCRGPPDRRGPH--PDFPDD 1012 MG M ++ +Q + GP E+G P + GQ G P + GP P Sbjct: 943 MGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQ--AGQPGQPGPKGDPGISGT 1000 Query: 1013 FSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARG 1072 P P G G G P EK G PGP P G G Sbjct: 1001 PGAPGLPGPKGSVG-------GMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAG 1053 Query: 1073 PPGAW-EGRR--PGDERFPRDPEDPRFRGRREESFRRGAP--PRHEGRAPPRGRDGFPG- 1126 PPG G R GD+ P P +G + G P P +G G G PG Sbjct: 1054 PPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGL 1113 Query: 1127 PEDFGPE--ENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDG 1184 P + G + D L G T G+KG P D P G + G Sbjct: 1114 PGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGE-PGSDGIPGSAGEKGEPGLPG 1172 Query: 1185 NREPG-PGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSE 1243 PG PG + + + P SP S QG M P+ +P PG+ Sbjct: 1173 RGFPGFPGAKGDKGSKGEVGFPGLAGSPGI-PGSKGEQGF-MGPPGPQGQPGL--PGSPG 1228 Query: 1244 HREMEAPGGPSEDRGGKGRGG----PGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG 1299 H A GP DRG +G+ G PGP G + + G+ GP G Sbjct: 1229 H----ATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKG 1284 Query: 1300 S----GTPSRGGRSGSNWGRGSNMNSGPP 1324 G P GG G GS + GPP Sbjct: 1285 DPGFQGMPGIGGSPGIT---GSKGDMGPP 1310 Score = 184 bits (468), Expect = 4e-46 Identities = 251/854 (29%), Positives = 309/854 (36%), Gaps = 145/854 (16%) Query: 575 PPSSGTPLLGPQPFPG-QGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 P GTP GP PG QGP+ P GF GPPGP G PPG +G Sbjct: 178 PGIPGTP--GPPGLPGLQGPVG--PPGFT---------------GPPGPPGPPGPPGEKG 218 Query: 634 QMG-----PQGPPLHQGGGGPQGF--------------MGPQGPQGPP--QGLPRPQDMH 672 QMG P+G QG GP G G +G +G P QG+P + Sbjct: 219 QMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKG 278 Query: 673 GP--QGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG 730 P G + PG G G +G PG G G G +G QGP G +G GP GPPG G Sbjct: 279 EPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTG 338 Query: 731 PQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQG---------------- 774 P G G +G G PGPRG GP G+ G PG G+ P G Sbjct: 339 PLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGF 398 Query: 775 PLMGL-NPRGMQGPPGPRENQGPAPQ-----GMI--MGHPPQEMRGPHPPG--GLLGH-G 823 P L P G G PGP + GP Q G++ PP + P PG G +G G Sbjct: 399 PGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIG 458 Query: 824 PQEMRGPQ----EIRGMQGPP-PQGSMLGPPQEL--RGPPGSQSQQGPP--QGSLG-PPP 873 + +G +I G +GPP PQ GPP E+ G PG++ +G P G G P P Sbjct: 459 EKGQKGESCLICDIDGYRGPPGPQ----GPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGP 514 Query: 874 QG--GMQGPPGPQGQQNP------ARGPHPSQGPIPFQQQKTPLLGD----------GPR 915 QG G+ G PG +G+ +G G P Q T G GP+ Sbjct: 515 QGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPG-FPGQPGMTGRAGSPGRDGHPGLPGPK 573 Query: 916 APFNQEG--QSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSER 973 G GPP + G +G G PP PG GP GD +G GP S Sbjct: 574 GSPGSVGLKGERGPPGGVGFPGSRGDTG--PPGPPGYGPAGPIGD-KGQAGFPGGPGSPG 630 Query: 974 RHEQSGGP-EHGPERGPFRGGQDCRGPPDRRGPHPD--FPDDFSRPDDFHPDKRFGHRLR 1030 G P + P GP G + G P GP D FP RP P ++ Sbjct: 631 LPGPKGEPGKIVPLPGP-PGAEGLPGSPGFPGPQGDRGFPGTPGRPG--LPGEKGAVGQP 687 Query: 1031 EFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRD 1090 G P P+ G GPP P F+ G +G G PG + P Sbjct: 688 GIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGL 747 Query: 1091 PEDPRFRGRREESFRRGAPPRHEGRAPP-----RGRDGFPG-PEDFGPEENFDASEEAAR 1144 P P G + G P H PP RG G PG P G AR Sbjct: 748 PGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGAR 807 Query: 1145 GRDLRGRGRGTPRGGRKGLLPTPDEFPRFEG----GRKPDSWDGNREPGPGHEHFRDTPR 1200 G G+G P + FP F G G K D G P Sbjct: 808 GPP---GGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPG 864 Query: 1201 PDHPPHDGHSPASRERSSSLQGMDMASLP--------PRKRPWHDGPGTSEHREMEAPGG 1252 P P S+ + P P ++ H PG+S R G Sbjct: 865 QQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPR---GDPG 921 Query: 1253 PSEDRGGKG-RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDE--PFGGPPGSGTPSRGGRS 1309 D+G G G PG +V S+ G+ D + + P G G P G Sbjct: 922 LKGDKGDVGLPGKPGSMDKVD----MGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVP 977 Query: 1310 GSNWGRGSNMNSGP 1323 G + G GP Sbjct: 978 GKDGQAGQPGQPGP 991 Score = 183 bits (465), Expect = 8e-46 Identities = 229/727 (31%), Positives = 267/727 (36%), Gaps = 136/727 (18%) Query: 654 GPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGP 713 G +G +G +GLP Q + G GMQ GP GP GP G G G G G G +GPPG Sbjct: 43 GVKGQKGE-RGLPGLQGVIGFPGMQ---GPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGA 98 Query: 714 QGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ 773 G+ G G PG G GP GPPG G G G RG GPP G G PG G+ Sbjct: 99 SGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLP----- 153 Query: 774 GPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHP--PQEMRGPHPPGGLLGHGPQEMRGPQ 831 GM+G PG E G P ++ G P P PPG GP GP Sbjct: 154 ---------GMKGDPG--EILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPV---GPP 199 Query: 832 EIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP-QGSLGPPPQGGMQGPPGPQGQQN-- 888 G GPP GPP GPPG + Q G QG G G+ GPPG GQ Sbjct: 200 GFTGPPGPP------GPP----GPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQ 249 Query: 889 -----PARGPHPSQGPIPFQQQKTPLLGD-------GPRAPFNQEGQ-----STGPP--P 929 +G +G FQ P +G+ GPR ++G S G P P Sbjct: 250 EKGDFATKGEKGQKGEPGFQGM--PGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEP 307 Query: 930 LIPGL-GQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGP--EHGPE 986 PGL G+QG QG P PG G GP +G ER + + GP E GP+ Sbjct: 308 GYPGLIGRQGPQGEKGEAGPPGPPGIVIG--TGP----LGEKGERGYPGTPGPRGEPGPK 361 Query: 987 RGPFRGGQDCRGPPDRRGP----HPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQE 1042 P GQ GPP P P FP + D R F G P P Sbjct: 362 GFPGLPGQP--GPPGLPVPGQAGAPGFPGERGEKGD-----------RGFPGTSLPGPSG 408 Query: 1043 EKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREE 1102 G PG P PP G G PG PGD+ P P P F G E Sbjct: 409 RDGLPGPPGSPGPPG----QPGYTNGIVECQPGP-----PGDQGPPGIPGQPGFIGEIGE 459 Query: 1103 SFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGR----GRGTPRG 1158 ++G G G PGP+ E F A R L GR G P+G Sbjct: 460 KGQKGESCL---ICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQG 516 Query: 1159 -----GRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHS--P 1211 G+ G P EF F+ K D D PG T R P DGH P Sbjct: 517 TPGLIGQPGAKGEPGEF-YFDLRLKGDKGDPGFPGQPGM-----TGRAGSPGRDGHPGLP 570 Query: 1212 ASRERSSSLQGMDMASLP-----PRKRPWHDGPGTSEHREMEAPGGPSEDRGGKG-RGGP 1265 + S+ P P R PG + P GP D+G G GGP Sbjct: 571 GPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY----GPAGPIGDKGQAGFPGGP 626 Query: 1266 GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS-GTPSRGGRSGSNWGRGSNMNSGPP 1324 G G + P GPPG+ G P G G RG G P Sbjct: 627 GSPGLPGPKGEPGKI-----------VPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRP 675 Query: 1325 RRGASRG 1331 +G Sbjct: 676 GLPGEKG 682 Score = 167 bits (423), Expect = 6e-41 Identities = 197/653 (30%), Positives = 248/653 (37%), Gaps = 126/653 (19%) Query: 574 PPPSSGTP-LLGPQPFPGQGPMSQIPQGFQQPHP-----SQQMPMNMAQMGPPGPQGQFR 627 PP G P L GP G+ P G P P +Q +P Q G PG GQ Sbjct: 809 PPGGQGPPGLSGPPGIKGEKGFPGFP-GLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQG 867 Query: 628 PPG------PQGQMGPQGPPLHQGGGGP------------QGFMGPQGPQGPPQ------ 663 PG +G+MG G P G GP GF G GP+G P Sbjct: 868 APGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKG 927 Query: 664 --GLP-RPQDMH-----------GPQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQG 709 GLP +P M G QG + GP G G +G PG G G G G G Sbjct: 928 DVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPG 987 Query: 710 PPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQG 769 PGP+G G G PG G GP+G G G+ G PG +G+ G P P G G PG +G +G Sbjct: 988 QPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKG 1047 Query: 770 PVSQGPLMGLNPRGMQGPPGPRENQG----PAPQGM-----IMGHP--------PQEMRG 812 Q G+ G++G G + G P +G I G P P + Sbjct: 1048 EKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1107 Query: 813 PHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPP 872 P PG G + + G I G++G + + G P GP G Q+G P GS G P Sbjct: 1108 PGSPGLPGEKGDKGLPGLDGIPGVKG---EAGLPGTP----GPTGPAGQKGEP-GSDGIP 1159 Query: 873 PQGGMQGPPGPQGQQNP----ARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPP 928 G +G PG G+ P A+G S+G + F P L P P ++ Q P Sbjct: 1160 GSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF-----PGLAGSPGIPGSKGEQGFMGP 1214 Query: 929 PLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERG 988 P G QG G P +PG KGD RGP P G P +G Sbjct: 1215 P-----GPQGQPGL--PGSPGHATEGPKGD-RGPQGQPGLPGLPGPMGPPGLPGIDGVKG 1266 Query: 989 PFRGGQDCRGPPDRRGPHPD-----------FPDDFSRPDDFHPDKRFGHR----LREFE 1033 +G G P GP D P D P G + L + Sbjct: 1267 D-KGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQ 1325 Query: 1034 G-RGGPLPQEEKWRRGGPGPPFPPDHREFSEGD-GRGAARGPPGAWEGRR--PGDE---- 1085 G +G Q +G PGPP PP + +G+ G GPPG +G + PG + Sbjct: 1326 GIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGL-KGLQGLPGPKGQQG 1384 Query: 1086 -----RFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPE 1133 P P P F G + G A P G GFPGP GP+ Sbjct: 1385 VTGLVGIPGPPGIPGFDGAPGQKGEMGP-------AGPTGPRGFPGPP--GPD 1428 Score = 163 bits (412), Expect = 1e-39 Identities = 135/374 (36%), Positives = 165/374 (44%), Gaps = 66/374 (17%) Query: 575 PPSSGTP-LLGPQPFPGQ-GPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRP--PG 630 P G P + G PG GP P G + S +P + + G PG G+ P PG Sbjct: 1123 PGLDGIPGVKGEAGLPGTPGPTG--PAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPG 1180 Query: 631 PQGQMGPQGP---------PLHQGGGGPQGFMGPQGPQGPPQGLPR--------PQDMHG 673 +G G +G P G G QGFMGP GPQG P GLP P+ G Sbjct: 1181 AKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQP-GLPGSPGHATEGPKGDRG 1239 Query: 674 PQGMQRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQG 733 PQG PG GP+GP G PG G G +G+ G G PG G P+G PG QG G G Sbjct: 1240 PQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPG---PKGDPGFQGMPGIGG 1296 Query: 734 PPG---TQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGP 790 PG ++G GPPG G QGP G+QG G QG QG +G+ GPPGP Sbjct: 1297 SPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGA--------KGLPGPPGP 1348 Query: 791 RENQGPAPQGMIMGHPPQEMRGPHPPGGLLG----HGPQEMRGPQEIRGMQGPPPQGSML 846 P P +I G P + GP P GL G GP+ +G + G+ GPP Sbjct: 1349 -----PGPYDIIKGEPG--LPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPP------ 1395 Query: 847 GPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQ---GQQNPARGPHPSQGPIPFQ 903 G P G PG + + GP GP G GPPGP G P P G + + Sbjct: 1396 GIPG-FDGAPGQKGEMGPA----GPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTR 1450 Query: 904 QQKTPLLGDGPRAP 917 +T D P+ P Sbjct: 1451 HSQTI---DDPQCP 1461 Score = 123 bits (308), Expect = 1e-27 Identities = 93/252 (36%), Positives = 111/252 (44%), Gaps = 39/252 (15%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQG-------QF 626 PP G P L P G ++ P+G + P +P MGPPG G + Sbjct: 1214 PPGPQGQPGLPGSP----GHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKG 1269 Query: 627 RP--PGPQGQMGPQGPPLHQGG---GGPQGFMGPQGPQGPP--------QGLPRPQDMHG 673 P PG G GP+G P QG GG G G +G GPP +GLP Q + G Sbjct: 1270 NPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKG 1329 Query: 674 PQGMQRHPGPHGPLGPQGPPGP-------------QGSSGPQGHMGPQGPPGPQGHIGPQ 720 QG Q PG G GP GPPGP +G G +G G GP G QG G Sbjct: 1330 DQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLV 1389 Query: 721 GPPGPQGHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQG--PVSQGPLMG 778 G PGP G G G PG +G GP GP G +G P P G G PGS G G V G L+ Sbjct: 1390 GIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVT 1449 Query: 779 LNPRGMQGPPGP 790 + + + P P Sbjct: 1450 RHSQTIDDPQCP 1461 Score = 60.8 bits (146), Expect = 8e-09 Identities = 122/459 (26%), Positives = 152/459 (33%), Gaps = 96/459 (20%) Query: 882 GPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQG 941 G +GQ+ RG QG I F + P +GP+ P Q+G TG P L G +G G Sbjct: 43 GVKGQKGE-RGLPGLQGVIGFPGMQGP---EGPQGPPGQKGD-TGEPGLPGTKGTRGPPG 97 Query: 942 RIP-PLNPGQGPGPNKGDSRGPPNHH--MGPMSERRHEQSGGPEHGPERGPFRGGQDCRG 998 P NPG P + GPP G ER GP P F G G Sbjct: 98 ASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGER------GPLGPPGLPGFAGNP---G 148 Query: 999 PPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDH 1058 PP G D P + GH G L + E+ G PG P PP Sbjct: 149 PPGLPGMKGD------------PGEILGHV-------PGMLLKGERGFPGIPGTPGPPGL 189 Query: 1059 REFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPP 1118 G GPPG P P P +G+ SF+ P +G Sbjct: 190 PGLQGPVGPPGFTGPPGP-----------PGPPGPPGEKGQMGLSFQ--GPKGDKGDQGV 236 Query: 1119 RGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRK 1178 G G PG +E D + + +G+ +G P G KG P PR + G+ Sbjct: 237 SGPPGVPGQAQV--QEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPG--PRGKPGKD 292 Query: 1179 PDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDG 1238 D + PG P +P G E+ + PP G Sbjct: 293 GDKGEKGSPGFPGE--------PGYPGLIGRQGPQGEKGEAG--------PPGPPGIVIG 336 Query: 1239 PGT-SEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGP 1297 G E E PG P RG PGP G+ GP Sbjct: 337 TGPLGEKGERGYPGTPGP------RGEPGPKGFPGLPGQP------------------GP 372 Query: 1298 PGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRGR 1336 PG P + G G RG + G P G S G GR Sbjct: 373 PGLPVPGQAGAPGFPGERGEKGDRGFP--GTSLPGPSGR 409 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 206 bits (525), Expect = 9e-53 Identities = 257/812 (31%), Positives = 306/812 (37%), Gaps = 116/812 (14%) Query: 584 GPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPLH 643 GP F G P+GF P + + + G PG G PGP G G G P Sbjct: 677 GPPGFDGPPG----PKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDP-- 730 Query: 644 QGGGGPQGF--MGPQGPQGPP-----QGLPR-PQDMH----GPQGMQRHPGPHGPLGPQG 691 G GG +G +GP GP G P +G+P P H G +G+ PG GP G G Sbjct: 731 -GFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPG 789 Query: 692 PPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQG 751 PG +G +G G +G +GP G +GH G G PGP GH +G PG G G PG G G Sbjct: 790 CPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPG 849 Query: 752 PPHPHGIQGGPGSQGIQGPVSQGPLMGLNPR-GMQGPPGPRENQGPAPQGMIMGHPPQEM 810 P G +G PG G GP L GL R G GPPG GP + G P Sbjct: 850 AP---GGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPP---- 902 Query: 811 RGPHPPGGLLGH----GPQEMRGPQEIRGMQGPPPQGSMLGPPQE--LRG------PPGS 858 GP P GL G G + G + G +G P + M G P + LRG PPG Sbjct: 903 -GPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGD 961 Query: 859 Q------SQQGPPQGSLGPPPQGGMQGPPGPQGQ--QNPARGPHPSQGPIPFQQQKTPLL 910 + SQ+G P G GPP G G G +G RG GP F + + Sbjct: 962 EGEMAIISQKGTP-GEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEK 1020 Query: 911 GD-GPRAPFNQEGQSTGPPPLI--PGL-GQQGAQGRIPP-----LNPGQGPGPNKGDSRG 961 G GP P G STG I PGL G QG G P ++ +GP NKGD Sbjct: 1021 GQPGPPGPPGPPG-STGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGD--- 1076 Query: 962 PPNHHMGPMSERRHEQSGG-PEHGPERGP--FRGGQDCRGPPDRRGPH-----PDFPDDF 1013 P H GP + S G P H G G Q RG P R GP P P D Sbjct: 1077 -PASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDH 1135 Query: 1014 SRPDDFHPDKRFGHRLREFEGR-GGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARG 1072 P LR G G P P + +G PG P PP + S G G Sbjct: 1136 GMPG-----------LRGQPGEMGDPGP---RGLQGDPGIPGPPGIKGPSGSPGLNGLHG 1181 Query: 1073 PPG--AWEGRRPGDERFPRDPED-PRFRGRREESFRRGAPPRHEGRAPPRGRDGFPGPED 1129 G +G + P P P +G R + G P PRG+ G PGP Sbjct: 1182 LKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISP-----PGPRGKKGPPGP-- 1234 Query: 1130 FGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRK--PDSWDGNRE 1187 P + A GR + P G + P PD PR G P S D R Sbjct: 1235 --PGSSGPPGPAGATGRAPKDIPDPGPPGDQGP--PGPDG-PRGAPGPPGLPGSVDLLRG 1289 Query: 1188 PGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLP---PRKRPWHDGPGTSEH 1244 PG P P PP P + G D P P + H PG Sbjct: 1290 E-PGDCGLPGPPGPPGPP----GPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGE 1344 Query: 1245 REMEAPGGPSEDRGGKG-RGGPGPAQRVPKSGRSSSLDG----EHHDGYHRDEPFGGPPG 1299 + + P G G G RG PGP V R L G +G GP G Sbjct: 1345 KGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSG 1404 Query: 1300 SGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 G G G G + GPP R G Sbjct: 1405 PGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTG 1436 Score = 205 bits (522), Expect = 2e-52 Identities = 207/618 (33%), Positives = 247/618 (39%), Gaps = 140/618 (22%) Query: 575 PPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQ 634 P + G P G + PG+ MS +P + + +GPPG +G+ +G Sbjct: 923 PGAEGCP--GAKGEPGEKGMSGLPG-------DRGLRGAKGAIGPPGDEGEMAIISQKGT 973 Query: 635 MGPQGPPLHQGGGGPQGFMGPQGPQGPP--QGLPRPQDMHGPQGMQR-HPGPHGPLGPQG 691 G GPP G GF G +G +G P QG +GP G R PG G GP G Sbjct: 974 PGEPGPP------GDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPG 1027 Query: 692 PPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQ----GPPGPR 747 PPGP GS+G +G +G G PG QG G GPPG G G +GP G +G GPPGP+ Sbjct: 1028 PPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPK 1087 Query: 748 GMQGPPHPHGIQGGPGSQG---IQGPVSQGPLMGLNPRGMQGPPG-------------PR 791 G G P G G G QG IQGP G P G GPPG P Sbjct: 1088 GEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPG--PPGSSGPPGCPGDHGMPGLRGQPG 1145 Query: 792 ENQGPAPQGMIMGHP----PQEMRGPHPPGGLLG-HGPQEMRGPQEIRGMQ--GPPPQGS 844 E P P+G+ G P P ++GP GL G HG + +G + G+ GPP Sbjct: 1146 EMGDPGPRGL-QGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVG 1204 Query: 845 MLGPPQELRGPPGSQSQQGP-PQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQ 903 + G E RG PGS P P+G GPP G GPPGP G A P GP Q Sbjct: 1205 IPGLKGE-RGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQ 1263 Query: 904 QQKTPLLGDGPRAPFNQEGQSTGPPPLIPGL-----GQQGAQGRIPPLNPGQGPGPNKGD 958 P DGPR + GPP L PG G+ G G P P PGP Sbjct: 1264 GPPGP---DGPRG-------APGPPGL-PGSVDLLRGEPGDCGLPGPPGP---PGPP--- 1306 Query: 959 SRGPPNHHMGPMSERRHEQSG-----GPEHGPERGPFRGGQD-CRGPPDRRGPHPDFPDD 1012 GPP + P + + Q G GP+ GP P G+ GPP R+GP Sbjct: 1307 --GPPGYKGFPGCDGKDGQKGPVGFPGPQ-GPHGFPGPPGEKGLPGPPGRKGP------- 1356 Query: 1013 FSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEG-DGRGAAR 1071 G GP RG PGPP D G G R Sbjct: 1357 --------------------TGLPGP--------RGEPGPPADVDDCPRIPGLPGAPGMR 1388 Query: 1072 GPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAP-----PRHEGRAPPRGRDGFPG 1126 GP GA PG R P P +G RRG P GR G DG+PG Sbjct: 1389 GPEGAMG--LPG----MRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPG 1442 Query: 1127 ------------PEDFGP 1132 P+ FGP Sbjct: 1443 GPGPPGPIGDPGPKGFGP 1460 Score = 203 bits (516), Expect = 1e-51 Identities = 261/872 (29%), Positives = 314/872 (36%), Gaps = 219/872 (25%) Query: 584 GPQPFPGQGPM---SQIPQGFQQPHPSQQMPMNMAQMGPPGPQG---------QFRPPGP 631 GPQ FPG + + IP P + G PG QG PGP Sbjct: 408 GPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGP 467 Query: 632 QGQMGPQGPPLHQGGGGPQGFMG----------PQGPQGPPQGLPRPQDMHGPQGMQRHP 681 QG G GPP GG GP+G G P GP GPP GLP Q G G+ P Sbjct: 468 QGIKGKVGPP---GGRGPKGEKGNEGLCACEPGPMGPPGPP-GLPGRQGSKGDLGL---P 520 Query: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP------- 734 G G G GPPG +G G G G GPPG +G G +GH G +GP Sbjct: 521 GWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFP 580 Query: 735 --PGTQGMQGPPGPRGMQGPP--HPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGP 790 PG+ G G G +G GPP H GG G G GP + +G G GPPG Sbjct: 581 GQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGE 640 Query: 791 RENQGPAPQGMIMG---------------------HPPQEMRGPHPPGGLLG-------- 821 R + G + G H P GP P G G Sbjct: 641 RGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLS 700 Query: 822 -----------HGPQEMRGPQEIRGMQGPPPQG-----SMLGPPQELRGPPGSQSQQG-- 863 G E+ GP RG G P G S +GPP GPPGS G Sbjct: 701 GSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPP----GPPGSPGVNGQK 756 Query: 864 -----PPQGSLGPPPQGGMQGPPGPQGQQNP-----ARGPHPSQGPIPFQQQKTPLLGDG 913 P G LGPP + G+ G PG +G + A GP G + G Sbjct: 757 GIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFL------------G 804 Query: 914 PRAPFNQEGQS-----TGPP--------PLIPGLGQQGAQGRIPPLNPGQGPGPNKGDSR 960 + P +EG + GPP P IP GQ G G P +PG G + Sbjct: 805 LKGPKGREGHAGFPGVPGPPGHSCERGAPGIP--GQPGLPGY--PGSPGAPGGKGQPGDV 860 Query: 961 GPPNHHMGPMSERRHEQSGG--PEHGPE-----RGPFRGGQDCRGPPDRRGPH-----PD 1008 GPP GP + G HGP GPF G GPP +GP P Sbjct: 861 GPP----GPAGMKGLPGLPGRPGAHGPPGLPGIPGPF-GDDGLPGPPGPKGPRGLPGFPG 915 Query: 1009 FPDDFSRPD-DFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPP-DHREFSEGDG 1066 FP + +P + P + + G G ++ RG G PP D E + Sbjct: 916 FPGERGKPGAEGCPGAKGEPGEKGMSGLPG-----DRGLRGAKGAIGPPGDEGEMAIISQ 970 Query: 1067 RGAARGPPGAWEGRRPGDERFPRDPED---PRFRGRREESFRRGAPPRHEGRAPPRGRDG 1123 +G G PG PGD+ FP + D P +GRR E R G P H G +G+ G Sbjct: 971 KGTP-GEPGP-----PGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPG 1024 Query: 1124 FPGPEDFGPEENFDASEEAARGRDLRG--RGRGTPRGGRKGLLPTPDEFPRFEGGRKPDS 1181 PGP GP + LRG G P + P P F +G R P Sbjct: 1025 PPGPP--GPPGS----------TGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKG 1072 Query: 1182 WDGN-----REPGPGHEHFRDTPRPDHPPHDGHSPASRERS-SSLQGMDMASLPPRKRPW 1235 G+ PGP E P P GH AS E+ +QG PR P Sbjct: 1073 NKGDPASHFGPPGPKGE-------PGSPGCPGHFGASGEQGLPGIQG-------PRGSPG 1118 Query: 1236 HDGPGTSEHREMEAPGGPSEDRGGKG-RGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPF 1294 GP S P G D G G RG PG + G D Sbjct: 1119 RPGPPGS-----SGPPGCPGDHGMPGLRGQPG------------EMGDPGPRGLQGDPGI 1161 Query: 1295 GGPPG----SGTPSRGGRSGSNWGRGSNMNSG 1322 GPPG SG+P G G +G+ SG Sbjct: 1162 PGPPGIKGPSGSPGLNGLHGLKGQKGTKGASG 1193 Score = 193 bits (490), Expect = 1e-48 Identities = 249/865 (28%), Positives = 311/865 (35%), Gaps = 210/865 (24%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 GPPGP PGPQG +GP G P G G G G +G +GPP G + GP G+ Sbjct: 65 GPPGP------PGPQGPIGPLGAP---GPIGLSGEKGMRGDRGPP-GAAGDKGDKGPTGV 114 Query: 678 QRHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGP--- 734 PG G G GPPGP+G G GH G +G PG G G GP GP GH G +G Sbjct: 115 PGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGN 174 Query: 735 -----------------------PGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQG-- 769 PG+ G GP GP G G P G G PG G++G Sbjct: 175 SVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNP 234 Query: 770 ----------------PVSQGPLMGLNPR------------------GMQGPPGPRENQG 795 S GP + + P G+ GPPG + G Sbjct: 235 GVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG 294 Query: 796 PAPQGM--IMGHP-----PQEMRGPHPPG-----GLLGH-GPQEMRGPQEIRGMQG-PPP 841 +G I G P P P PG GL+G G + GP+ G +G P P Sbjct: 295 IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354 Query: 842 QGSMLGPPQELRGPPGSQSQQG--PPQGSLGPP-PQG----------GMQGPPGPQGQQN 888 G ++ PP L+GPPG G G +GPP P G GM GPPGPQG Sbjct: 355 PGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQG--F 412 Query: 889 PARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPL--IPGL----------GQ 936 P P + IP + P P +P G P L +PG G Sbjct: 413 PGLPGLPGEAGIPGRPDSAPGKPGKPGSP-----GLPGAPGLQGLPGSSVIYCSVGNPGP 467 Query: 937 QGAQGRIPPLNPGQGPGPNKGDS---------RGPPNHHMGPMSERRHEQSGGPEHGPER 987 QG +G++ P G+GP KG+ GPP P + G P + Sbjct: 468 QGIKGKVGPPG-GRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTK 526 Query: 988 GPFRGGQDCRGPPDRRGPH--PDFPDDFSRPDDFHPDKRFGHRLRE-------FEGRGGP 1038 G G GPP G H P + D + GH+ F G+ G Sbjct: 527 GD-PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGS 585 Query: 1039 LPQE-EKWRRGGPGPPFPPDHREFSEG----------DGRGAARGPPGAWEGRRPGDERF 1087 ++ +G PGP P DH + + G G+ GPPG PG+ Sbjct: 586 HGRDGHAGEKGDPGP--PGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGH 643 Query: 1088 PRDPEDPRFRGRREESFRRG----APPRHEGRAPPRGRDGFPGPEDF-GPEENFDASEEA 1142 P P P RG ++G + GR P G DG PGP+ F GP + Sbjct: 644 PGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGP--------QG 695 Query: 1143 ARGRDLRGRGRGTPRGGRKGLLPTPDEF------PRFEGGRKPDSWDGNREPGPGHEHFR 1196 A G +G P +P P F P F GG K S G PGP Sbjct: 696 APGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGF-GGEKGSSPVG--PPGP------ 746 Query: 1197 DTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSED 1256 P P +G + + G PP KR PG GP D Sbjct: 747 ----PGSPGVNGQKGIPGDPAFGHLG------PPGKRGLSGVPGIK---------GPRGD 787 Query: 1257 RGGKGRGGP----------GPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRG 1306 G G GP GP R +G + G R P G P G P Sbjct: 788 PGCPGAEGPAGIPGFLGLKGPKGREGHAG-FPGVPGPPGHSCERGAP-GIPGQPGLPGYP 845 Query: 1307 GRSGSNWGRGSNMNSGPPRRGASRG 1331 G G+ G+G + GPP +G Sbjct: 846 GSPGAPGGKGQPGDVGPPGPAGMKG 870 Score = 193 bits (490), Expect = 1e-48 Identities = 250/839 (29%), Positives = 301/839 (35%), Gaps = 174/839 (20%) Query: 582 LLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPP 641 L+GP+ PG +G P P + + GPPG G G G +GP GPP Sbjct: 339 LIGPKGDPGN-------RGHPGP-PGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPP 390 Query: 642 --LHQGGGGPQGFMGPQGPQGPP--QGLP-------RPQDMHGPQGMQRHPGPHGPLGPQ 690 L + G G +GP GPQG P GLP RP G G PG G G Q Sbjct: 391 GLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQ 450 Query: 691 GPPGPQ------GSSGPQGHMGPQGPPGPQG-------------HIGPQGPPGP------ 725 G PG G+ GPQG G GPPG +G GP GPPGP Sbjct: 451 GLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGR 510 Query: 726 QGHLGPQGPPGTQGMQGPPGPRGMQGPPH---PHGIQGGPGSQGIQGPVSQGPLMGLNPR 782 QG G G PG G +G PGP G +GPP HG G PG++G +G + + G + Sbjct: 511 QGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKG--HK 568 Query: 783 GMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGP--QEMRGPQEIRGMQGP- 839 G +GP GP G GH E P PPG P + GP G GP Sbjct: 569 GERGPDGPPGFPGQPGSHGRDGHAG-EKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPV 627 Query: 840 -PPQGSMLGPPQE-----------LRGPPGSQSQQGPP-------QGSLGPPPQGGMQGP 880 PP GPP E +RGP G + Q+G G GPP G GP Sbjct: 628 GPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPP---GFDGP 684 Query: 881 PGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQ 940 PGP+G P P S + TP + P P + PG G + Sbjct: 685 PGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGD------PGFGGEKGS 738 Query: 941 GRIPPLNPGQGPGPN--KGDSRGPPNHHMGPMSERRHEQSGGPE-HGPERGPFRGGQD-- 995 + P P PG N KG P H+GP +R SG P GP P G + Sbjct: 739 SPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRG--LSGVPGIKGPRGDPGCPGAEGP 796 Query: 996 --------CRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGR----GGPLPQEE 1043 +GP R G H FP P H +R + G G P Sbjct: 797 AGIPGFLGLKGPKGREG-HAGFPGVPGPPG--HSCERGAPGIPGQPGLPGYPGSPGAPGG 853 Query: 1044 KWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRP-GDERFPRDPEDPRFRGRREE 1102 K + G GPP P + GR A GPPG P GD+ P Sbjct: 854 KGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLP-------------- 899 Query: 1103 SFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKG 1162 PP +G PRG GFPG P E E G +G P G KG Sbjct: 900 -----GPPGPKG---PRGLPGFPG----FPGERGKPGAEGCPG------AKGEP--GEKG 939 Query: 1163 LLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASR--ERSSSL 1220 + P + R G K E + TP PP D P R + + + Sbjct: 940 MSGLPGD--RGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGM 997 Query: 1221 QGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSL 1280 QG R P GP PG + G KG+ GP P S Sbjct: 998 QGR-------RGEPGRYGP----------PGFHRGEPGEKGQPGPPGPPGPPGSTGLRGF 1040 Query: 1281 DGEHHDGYHRDEPFGGPPGS----GTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGRG 1335 G F G PG G+P G SG + RG N G P G +G Sbjct: 1041 IG-----------FPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKG 1088 Score = 189 bits (479), Expect = 2e-47 Identities = 219/681 (32%), Positives = 255/681 (37%), Gaps = 121/681 (17%) Query: 574 PPPSS---GTPLLGPQP-FPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPP 629 PP S G P + QP PG P G QP +GPPGP G P Sbjct: 823 PPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQP----------GDVGPPGPAGMKGLP 872 Query: 630 GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGP--PQGLPRPQDMHGPQGMQRHPGPHGPL 687 G G+ G GPP G GP G G GP GP P+GLP G +G PG G Sbjct: 873 GLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGK---PGAEGCP 929 Query: 688 GPQGPPGPQGSSGPQGHMGPQG------PPGPQGHI---------GPQGPPGPQGHLGPQ 732 G +G PG +G SG G G +G PPG +G + G GPPG G G + Sbjct: 930 GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989 Query: 733 GPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ-GPLMGLNPRGMQGPPGPR 791 G GT GMQG G G GPP H +G PG +G GP GP RG G PG Sbjct: 990 GDKGTPGMQGRRGEPGRYGPPGFH--RGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLP 1047 Query: 792 ENQG----PAPQGMI-----------MGHPPQEMRGPHPPG-----GLLGHGPQEMRGPQ 831 +QG P P G G P P P G G GH G Q Sbjct: 1048 GDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGAS--GEQ 1105 Query: 832 EIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP-----QGSLGPPPQGGMQGPPGPQGQ 886 + G+QGP GPP GPPG G P G +G P G+QG PG G Sbjct: 1106 GLPGIQGPRGSPGRPGPPGS-SGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGP 1164 Query: 887 QNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEG-QSTGPP-PL-IPGL----GQQGA 939 +GP S G K G + G GPP P+ IPGL G G+ Sbjct: 1165 PG-IKGPSGSPGLNGLHGLK------GQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGS 1217 Query: 940 QGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGP 999 G PP G+ P S GPP GP P+ GP P Sbjct: 1218 PGISPPGPRGKKGPPGPPGSSGPP----GPAGATGRAPKDIPDPGP-------------P 1260 Query: 1000 PDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHR 1059 D+ P PD P P LR G G LP G PGPP PP ++ Sbjct: 1261 GDQGPPGPDGPRGAPGPPGLPGSVDL---LRGEPGDCG-LPGPP----GPPGPPGPPGYK 1312 Query: 1060 EFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRAPPR 1119 F DG+ +GP G + G + G FP P + G G P PP Sbjct: 1313 GFPGCDGKDGQKGPVG-FPGPQ-GPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPA 1370 Query: 1120 GRD------GFPG-PEDFGPEENFDASEEAARGRDLRGRGRGTPRGGRKGLLPTPDEFPR 1172 D G PG P GPE RG G GR+G+ D P Sbjct: 1371 DVDDCPRIPGLPGAPGMRGPEGAMGL--PGMRGPSGPGCKGEPGLDGRRGV----DGVPG 1424 Query: 1173 FEG--GRKPDSWDGNREPGPG 1191 G GRK D+ + GPG Sbjct: 1425 SPGPPGRKGDTGEDGYPGGPG 1445 Score = 185 bits (470), Expect = 2e-46 Identities = 171/508 (33%), Positives = 205/508 (40%), Gaps = 88/508 (17%) Query: 574 PPPSSGTP-LLGPQPFPG-QG----PMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFR 627 PP G P G + PG QG P P GF + P ++ Q GPPGP G Sbjct: 979 PPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEK-----GQPGPPGPPGPPG 1033 Query: 628 PPGPQGQMGPQGPPLHQG---GGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGP- 683 G +G +G G P QG GP GF G G +GP P GP G + PG Sbjct: 1034 STGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSP 1093 Query: 684 -----HGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQ 738 G G QG PG QG G G GP G GP G G G PG +G G G PG + Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR 1153 Query: 739 GMQGPPG---PRGMQGPPHP------HGIQGGPGSQGIQGPVSQGP-----LMGL----- 779 G+QG PG P G++GP HG++G G++G G GP + GL Sbjct: 1154 GLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERG 1213 Query: 780 ----------NPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRG 829 PRG +GPPGP + GP G P+++ P PPG GP G Sbjct: 1214 DPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPG---DQGPP---G 1267 Query: 830 PQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGP--PQGSLGPPPQGGMQGPPGPQGQQ 887 P RG GPP + G LRG PG GP P G GPP G G G GQ+ Sbjct: 1268 PDGPRGAPGPP---GLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQK 1324 Query: 888 NPA-----RGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGPP------PLIPGL-- 934 P +GPH GP + P GP G+ GPP P IPGL Sbjct: 1325 GPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGE-PGPPADVDDCPRIPGLPG 1383 Query: 935 -----GQQGAQGRIPPLNPGQGPG----PNKGDSRGPPNHHMGPMSERRHEQSGGPEHGP 985 G +GA G +P + GPG P RG P R +G E G Sbjct: 1384 APGMRGPEGAMG-LPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTG--EDGY 1440 Query: 986 ERGPFRGGQDCRGPPDRRGPHPDFPDDF 1013 GP G G P +G P + F Sbjct: 1441 PGGP--GPPGPIGDPGPKGFGPGYLGGF 1466 Score = 121 bits (303), Expect = 5e-27 Identities = 93/268 (34%), Positives = 106/268 (39%), Gaps = 71/268 (26%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQG 633 PP SSG P GP G+ P P P GPPG QG P GP+G Sbjct: 1234 PPGSSGPP--GPAGATGRAPKDI-------PDP-----------GPPGDQGPPGPDGPRG 1273 Query: 634 QMGPQGPP----LHQGGGGPQGFMGPQGPQGPP-----QGLPRPQDMHGPQGMQRHPGPH 684 GP G P L +G G G GP GP GPP +G P G +G PGP Sbjct: 1274 APGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQ 1333 Query: 685 GPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQ----------GPPGPQGHLGPQGP 734 GP G GPPG +G GP G GP G PGP+G GP G PG G GP+G Sbjct: 1334 GPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGA 1393 Query: 735 PGTQGMQGPPGPR--------------------------------GMQGPPHPHGIQGGP 762 G GM+GP GP G G P P G G P Sbjct: 1394 MGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDP 1453 Query: 763 GSQGIQGPVSQGPLMGLNPRGMQGPPGP 790 G +G G L+ L+ + Q P P Sbjct: 1454 GPKGFGPGYLGGFLLVLHSQTDQEPTCP 1481 Score = 50.4 bits (119), Expect = 1e-05 Identities = 136/552 (24%), Positives = 171/552 (30%), Gaps = 137/552 (24%) Query: 864 PPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQ 923 P +GS GPP G QGP GP G + GPI +K GP +G Sbjct: 59 PEKGSRGPPGPPGPQGPIGPLG----------APGPIGLSGEKGMRGDRGPPGAAGDKGD 108 Query: 924 STGPPPLIPGL-GQQGAQGRIPPLNPGQGPG-PNKGDSRGPPNH-----HMGPMSERRHE 976 P +PG G G G P P PG SRG P +GP H Sbjct: 109 K--GPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHP 166 Query: 977 QSGGPEHGPE---RGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFE 1033 G E G G +G Q RG P P P + Sbjct: 167 GEKG-EKGNSVFILGAVKGIQGDRGDPGL----PGLPGSW-------------------- 201 Query: 1034 GRGGPL-PQEEKWRRGGPGPPFPPDHREFSEGDGRG--AARGPPG-AWEGRRPGDERFPR 1089 G GGP P G GPP P G G G PG + PG Sbjct: 202 GAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVE 261 Query: 1090 DPEDPRFRGRREESFRRG-----APPRHEGRA-----PPRGRDGFPGPE----DFGPEEN 1135 P+ ++G + G PP +G + +G GFPGP +G Sbjct: 262 PPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGF 321 Query: 1136 FDASEEAARGRDLRGRGRGTPRG--------GRKGLLPT-------PDEFPRFEG----- 1175 E D G P+G G G+L T P P F G Sbjct: 322 PGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGET 381 Query: 1176 ------------GRKPDSWDGNREPGPGHEHFRDTP----------RPDHPPHDGHSPAS 1213 GR ++ G P PG + F P RPD P P S Sbjct: 382 GDVGPPGPPGLLGRPGEACAGMIGP-PGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGS 440 Query: 1214 --RERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGR--------- 1262 + LQG+ P + G + ++ GP RG KG Sbjct: 441 PGLPGAPGLQGL------PGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCAC 494 Query: 1263 --GGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGS-GTPSRGGRSGSNWGRGSNM 1319 G GP GR S G+ + GPPG+ G P G+ G+ Sbjct: 495 EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGA-------- 546 Query: 1320 NSGPPRRGASRG 1331 SGPP ++G Sbjct: 547 -SGPPGNKGAKG 557 >gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] Length = 416 Score = 205 bits (521), Expect = 3e-52 Identities = 175/457 (38%), Positives = 201/457 (43%), Gaps = 79/457 (17%) Query: 565 AQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQG 624 AQ E + S PQ P QG PQG P Q GPP PQG Sbjct: 16 AQNLNEDVSQEESPSLIAGNPQGAPPQG--GNKPQGPPSPPGKPQ--------GPP-PQG 64 Query: 625 QFRPPGPQGQMG-PQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGP 683 +P GP G PQGPP QGG PQG P PQGPP + + P G + P P Sbjct: 65 GNQPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 123 Query: 684 HGPLGPQGPPGPQG---SSGPQGHMGPQGPPGPQGHIGPQGPPGPQG---HLGPQGPPGT 737 G PQGPP P G PQG PQGPP P PQGPP PQG + PPG Sbjct: 124 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG---KPQGPP-PQGDNKSRSSRSPPGK 179 Query: 738 QGMQGPP--GPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQG 795 QGPP G QGPP P G GP QG P QGPP P + QG Sbjct: 180 P--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP--------------QGPPPPGKPQG 223 Query: 796 PAPQG----MIMGHPPQEMRGPHPPGGLLGHGPQEMRG------PQEIRGMQGPPPQGSM 845 P PQG PP + +GP P GG GP G PQ QGPPP G Sbjct: 224 PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 283 Query: 846 LGPPQELRGPPGSQSQQGPPQGSLGPPPQGG--MQGPPGPQGQQNPARGPHPSQGPIPFQ 903 GPP + G S+S + PP GPPPQGG QGPP P G+ +GP P G P Sbjct: 284 QGPPPQ--GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK---PQGPPPQGGNKP-- 336 Query: 904 QQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPGQGPGPNKGDS-RGP 962 GP P G+ GPP P G + R PP P QGP +G++ +GP Sbjct: 337 --------QGPPPP----GKPQGPP---PQGGSKSRSARSPPGKP-QGPPQQEGNNPQGP 380 Query: 963 PNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGP 999 P G + + +G P+ GP R P +GG+ R P Sbjct: 381 PPPAGGNPQQPQAPPAGQPQ-GPPRPP-QGGRPSRPP 415 Score = 177 bits (448), Expect = 8e-44 Identities = 162/445 (36%), Positives = 193/445 (43%), Gaps = 88/445 (19%) Query: 695 PQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGM-QGPP--GPRGMQG 751 PQG+ PQG PQGPP P G PQGPP PQG PQGPP G QGPP G QG Sbjct: 36 PQGAP-PQGGNKPQGPPSPPGK--PQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 91 Query: 752 PPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMR 811 PP P QG P QG S+ P + PPG + QGP PQG G+ PQ Sbjct: 92 PPPPGKPQGPPP----QGDKSRSP---------RSPPG--KPQGPPPQG---GNQPQGP- 132 Query: 812 GPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGP 871 P PPG G PQ PQ GPPP G GPP + G S+S + PP GP Sbjct: 133 -PPPPGKPQGPPPQGGNKPQ------GPPPPGKPQGPPPQ--GDNKSRSSRSPPGKPQGP 183 Query: 872 PPQGGMQ--GPPGPQG--QQNPARGPHPSQGPIP-FQQQKTPLLGDGP-RAPFNQEGQST 925 PPQGG Q GPP P G Q P +G + QGP P + Q P GD ++ + G+ Sbjct: 184 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQ 243 Query: 926 GPPPLIPGLGQQGAQGRIPPLNPG--QGPGP---NKGDSRGPPNHHMGPMSE--RRHEQS 978 GPPP Q G Q + PP PG QGP P NK PP GP + + S Sbjct: 244 GPPP------QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSS 297 Query: 979 GGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGP 1038 P P+ P +GG +GPP G +P P +GG Sbjct: 298 RSPPGKPQGPPPQGGNQPQGPPPPPG----------KPQGPPP-------------QGGN 334 Query: 1039 LPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRG 1098 PQ GP PP P G +AR PPG +G + P+ P P Sbjct: 335 KPQ-------GPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGN 387 Query: 1099 RREESFRRGAPPRHEGRAPPRGRDG 1123 ++ APP + + PPR G Sbjct: 388 PQQPQ----APPAGQPQGPPRPPQG 408 Score = 160 bits (404), Expect = 1e-38 Identities = 138/365 (37%), Positives = 153/365 (41%), Gaps = 80/365 (21%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPH----------PSQQMPMNMAQMGPPG-- 621 PPP G GP P PG+ P PQG +P P Q + + PPG Sbjct: 60 PPPQGGNQPQGPPPPPGK-PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKP 118 Query: 622 ----PQGQFRPPGPQGQMG-PQGPPLHQGGGGPQGFMGPQGPQGPP-QGLPRPQDMHGPQ 675 PQG +P GP G PQGPP QGG PQG P PQGPP QG + + P Sbjct: 119 QGPPPQGGNQPQGPPPPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPP 177 Query: 676 GMQRHPGPHGPLGPQGPPGPQGSSG---PQGHMGPQGPPGPQGHIGP------------- 719 G + P P G PQGPP P G PQG PQGPP P GP Sbjct: 178 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237 Query: 720 -----QGPPGPQGHLGPQGPPGTQGM-QGPP--GPRGMQGPPHPHGIQGGPGSQGIQGPV 771 QGPP PQG PQGPP G QGPP G QGPP P QG P G + Sbjct: 238 PPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296 Query: 772 SQGPLMGLNPRGMQGPP--GPRENQGPAPQ-GMIMGHPPQ---EMRGPHPPGGLLGHGPQ 825 S+ P P QGPP G + QGP P G G PPQ + +GP PPG G PQ Sbjct: 297 SRSP-----PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 351 Query: 826 -------------EMRGP--QEIRGMQGPPP---------QGSMLGPPQELRGPPGSQSQ 861 + +GP QE QGPPP Q G PQ PP Sbjct: 352 GGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 411 Query: 862 QGPPQ 866 PPQ Sbjct: 412 SRPPQ 416 Score = 127 bits (320), Expect = 5e-29 Identities = 144/489 (29%), Positives = 186/489 (38%), Gaps = 135/489 (27%) Query: 841 PQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQ--GPPGPQG--QQNPARGPHPS 896 PQG+ PPQ P G S G PQG PPPQGG Q GPP P G Q P +G + Sbjct: 36 PQGA---PPQGGNKPQGPPSPPGKPQG---PPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 89 Query: 897 QGPIP-FQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGLGQQGAQGRIPPLNPG--QGPG 953 QGP P + Q P GD R+P + G+ GPPP Q G Q + PP PG QGP Sbjct: 90 QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP------QGGNQPQGPPPPPGKPQGPP 143 Query: 954 P---NKGDSRGPPNHHMGP--MSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPD 1008 P NK PP GP + + S P P+ P +GG +GPP G Sbjct: 144 PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG---- 199 Query: 1009 FPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRG 1068 +P P +GG PQ GP PP P +GD + Sbjct: 200 ------KPQGPPP-------------QGGNKPQ-------GPPPPGKPQGPP-PQGDNKS 232 Query: 1069 -AARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHEGRA---PPRGRDGF 1124 +AR PPG +G P P+ P P + + G PP+ + PP G+ Sbjct: 233 QSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-------GPPPQGGNKPQGPPPPGKPQG 285 Query: 1125 PGPEDFGPEENFDASEEAARGRDLRGRGRGTP-RGGRKGLLPTPD----EFPRFEGGRKP 1179 P P+ ++ R G+ +G P +GG + P P + P +GG KP Sbjct: 286 PPPQ---------GGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 336 Query: 1180 DSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDMASLPPRKRPWHDGP 1239 P PG +P PP G S + RS PP K Sbjct: 337 QG-----PPPPG--------KPQGPPPQGGSKSRSARS-----------PPGK------- 365 Query: 1240 GTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHHDGYHRDEPFGGPPG 1299 P GP + G +G P PA P+ ++ P G P G Sbjct: 366 ----------PQGPPQQEGNNPQGPPPPAGGNPQQPQA--------------PPAGQPQG 401 Query: 1300 SGTPSRGGR 1308 P +GGR Sbjct: 402 PPRPPQGGR 410 Score = 73.6 bits (179), Expect = 1e-12 Identities = 110/419 (26%), Positives = 141/419 (33%), Gaps = 97/419 (23%) Query: 919 NQEGQSTGPPPLIPGLGQQGAQGRIPPL--NPGQGPGPNKGDSRGPPNHHMGPMSERRHE 976 N++ P LI G QGA PP N QGP G +GPP P + + Sbjct: 20 NEDVSQEESPSLIAG-NPQGA----PPQGGNKPQGPPSPPGKPQGPP-----PQGGNQPQ 69 Query: 977 QSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPD-DFSRPDDFHPDKRFGHRLREFEGR 1035 P P+ P +GG +GPP P P D SR P K G + Sbjct: 70 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP-----PPQ 124 Query: 1036 GGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPR 1095 GG PQ GPP PP G +GPP G +P P P+ P Sbjct: 125 GGNQPQ---------GPPPPP-----------GKPQGPPPQG-GNKPQGPPPPGKPQGPP 163 Query: 1096 FRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGT 1155 +G + R P + +G PP+G + GP G Sbjct: 164 PQGDNKSRSSRSPPGKPQG-PPPQGGNQPQGPPP----------------------PPGK 200 Query: 1156 PRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRE 1215 P+G P P +GG KP P P + P+ D+ SP + Sbjct: 201 PQG------PPP------QGGNKPQG------PPPPGKPQGPPPQGDNKSQSARSPPGKP 242 Query: 1216 RSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPA--QRVPK 1273 + QG + PP PG P GP G K +G P P Q P Sbjct: 243 QGPPPQGGNQPQGPPPP------PGK--------PQGPPPQGGNKPQGPPPPGKPQGPPP 288 Query: 1274 SGRSSSLDGEHHDGYHRDEP-FGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 G S S G + P GG G P G+ +G N GPP G +G Sbjct: 289 QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 347 Score = 60.1 bits (144), Expect = 1e-08 Identities = 93/409 (22%), Positives = 136/409 (33%), Gaps = 113/409 (27%) Query: 934 LGQQGAQGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGG 993 L AQ ++ + P G+ +G P P + + P P+ P +GG Sbjct: 11 LALSSAQNLNEDVSQEESPSLIAGNPQGAP-----PQGGNKPQGPPSPPGKPQGPPPQGG 65 Query: 994 QDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPP 1053 +GPP G +P P +GG PQ GP PP Sbjct: 66 NQPQGPPPPPG----------KPQGPPP-------------QGGNKPQ-------GPPPP 95 Query: 1054 FPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRGAPPRHE 1113 P +GD + R PPG +G P P+ P P + + G PP+ Sbjct: 96 GKPQGPP-PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ-------GPPPQGG 147 Query: 1114 GRA---PPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTP-RGGRKGLLPTPD- 1168 + PP G+ P P+ ++ R G+ +G P +GG + P P Sbjct: 148 NKPQGPPPPGKPQGPPPQ---------GDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPP 198 Query: 1169 ---EFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASRERSSSLQGMDM 1225 + P +GG KP P PG +P PP G + + RS Sbjct: 199 GKPQGPPPQGGNKPQG-----PPPPG--------KPQGPPPQGDNKSQSARS-------- 237 Query: 1226 ASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPKSGRSSSLDGEHH 1285 PP K P GP G + +G P P + G Sbjct: 238 ---PPGK-----------------PQGPPPQGGNQPQGPPPPPGKP---------QGPPP 268 Query: 1286 DGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRGGGR 1334 G ++ + GPP G P G + R S G P+ +GG + Sbjct: 269 QGGNKPQ---GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQ 314 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 204 bits (520), Expect = 4e-52 Identities = 277/903 (30%), Positives = 340/903 (37%), Gaps = 199/903 (22%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP-Q 632 PP G+P P P GP PQG +Q +P G GP+G+ P Sbjct: 597 PPGDPGSPG-SPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP 655 Query: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGP 692 G GP GPP H G GP G G G G P GLP P G G+ PGP GP G QG Sbjct: 656 GPPGPPGPPGHPGPQGPPGIPGSLGKCGDP-GLPGPDGEPGIPGIG-FPGPPGPKGDQGF 713 Query: 693 PGPQGSSGPQGHMGPQGPPGPQGHIG---------PQGP-----PGPQGHLGPQGP---- 734 PG +GS G G MG G PG G G P GP PG +G+ G G Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLP 773 Query: 735 -----PGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPG 789 PGT G +G GPRG G P P G QG PG + I+GP L GLN G++G G Sbjct: 774 GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLN--GLKGQQG 830 Query: 790 PRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH----GPQEMRGPQEIRGMQGPPPQGS- 844 R GP I G G G+ GH GP RG G+ GPP + Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGV 890 Query: 845 --MLGPPQELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQ--- 897 M+G P + GPPG G P +GS G P G +G PG +G+Q P PS+ Sbjct: 891 IGMMGFPGAI-GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 898 ----------------------GPIPFQQQKTPLLG-DGPRAPFNQEGQ--STGPPPL-- 930 +P L G GP P G STG P Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 931 ---IPG----LGQQGAQGR--------------IPPLNPGQG----PGPNKGDSRGPPNH 965 IPG +G G++G+ +P ++ QG PG ++G GPP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 966 --------HMGPMSERRHEQSGGPEH----GPERGPFRGGQDCRGPPDRRGPHPDFPDDF 1013 MG E Q G P H GPE P G G P + GPH D Sbjct: 1070 TGDPGLPGDMGKKGEMG--QPGPPGHLGPAGPEGAP--GSPGSPGLPGKPGPHGDLGFKG 1125 Query: 1014 SRPDDFHPDKRFGHRLREFEGRGGPLP-QEEKWRRGGPGPPFPPDHREFSEGDGRGAARG 1072 + P R L F G GP+ + ++ R G PGP E G R Sbjct: 1126 IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA--------GEKGETGLLRA 1177 Query: 1073 PPG-----AWEGRRPGDERFPRDPEDPRFRGRREESFRRG--------APPRHEG----- 1114 PPG +G + GD P P P +G ++ RG PP G Sbjct: 1178 PPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236 Query: 1115 ----RAPP--RGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRG---------- 1158 R PP RG G PGP GP + + +G G P+G Sbjct: 1237 QTGNRGPPGSRGSPGAPGPP--GPPGSHVIGIKGDKG----SMGHPGPKGPPGTAGDMGP 1290 Query: 1159 -GRKGL-----LPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPA 1212 GR G LP P P F+G GN PG F + P P P Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGN----PG---FLGSIGPPGPIGPKGPPG 1343 Query: 1213 SRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGP-GPAQRV 1271 R +L+ + SLP P PGT M+ GP G G GP GP + Sbjct: 1344 VRGDPGTLK---IISLPGSPGP----PGTPGEPGMQGEPGPP---GPPGNLGPCGPRGKP 1393 Query: 1272 PKSGRSSSLD--GEHHDGYHRDEPFGGPPGS-GTPSRGGRSGSNWGRGSNMNSGPPRRGA 1328 K G+ + GE + + EP GP GS G P G+ G +SG P Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEP--GPAGSDGLPGLKGKRG---------DSGSPATWT 1442 Query: 1329 SRG 1331 +RG Sbjct: 1443 TRG 1445 Score = 200 bits (509), Expect = 7e-51 Identities = 234/774 (30%), Positives = 284/774 (36%), Gaps = 162/774 (20%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 G PGP+G+ G +G GP G P G G GP GP GPP +GPQG Sbjct: 578 GLPGPKGELALSGEKGDQGPPGDP------GSPGSPGPAGPAGPPG--------YGPQG- 622 Query: 678 QRHPGPHGPLGPQGPPGPQGSSGPQGHM-------GPQGPPGPQGHIGPQGPPGPQGHLG 730 PG G G G PGP G +GP+G + GP GPPGP GH GPQGPPG G LG Sbjct: 623 --EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680 Query: 731 PQGPPGTQGMQGPPGPRGM--QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPP 788 G PG G G PG G+ GPP P G QG PG++G G + GL G G P Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLP--GKPGLP 738 Query: 789 GPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP--PQGSML 846 G + A G GP PG G G + G+ G P P L Sbjct: 739 GAKGEPAVAMPG-----------GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 847 GPPQELRGPPGSQSQQGPP-------QGSLGPPPQGGMQGPPGPQGQQNPARGPHP---S 896 P+ G PG +QGPP +G+ G P G++G G +G+ P P Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 897 QGPIPFQQQKTPLLG-DGPRAPFNQEGQSTGP----PPLIPG-LGQQGAQGRI----PPL 946 + P + + G G P Q G P PP G +G G G I PP Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 947 NPGQ-----GPG-PNKGDSRGPP-----------------NHHMGPMSERRHEQ-SGGPE 982 NPG PG P RG P +H +G E + +G P Sbjct: 908 NPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 983 HGPERGP--FRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLP 1040 RG G + +G P GP D S + P LR G G + Sbjct: 968 EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG------LRGIPGSMGNMG 1021 Query: 1041 QE-EKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGR 1099 K +RG G P G +G PG EG RPG DP P G+ Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 1100 REESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRG- 1158 + E + G PP H G A P G G PG G+ P G Sbjct: 1082 KGEMGQPG-PPGHLGPAGPEGAPGSPGSPGLP--------------------GKPGPHGD 1120 Query: 1159 ----GRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASR 1214 G KGLL P G R P PG F +P P D Sbjct: 1121 LGFKGIKGLLGPP----------------GIRGP-PGLPGFPGSPGPMGIRGD------- 1156 Query: 1215 ERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPK- 1273 QG D P ++ E + AP GP + G +G G A P Sbjct: 1157 ------QGRDGIPGPAGEK--------GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202 Query: 1274 SGRSSSLDGEHHDGYHRDEPFGGPPG---SGTPSRGGRSGSNWGRGSNMNSGPP 1324 GR ++ G E F GPPG + P + G G RGS GPP Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Score = 179 bits (455), Expect = 1e-44 Identities = 175/553 (31%), Positives = 218/553 (39%), Gaps = 82/553 (14%) Query: 567 KQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQF 626 +Q ++ P PS + ++G + PG + P G + MP G PGP G Sbjct: 935 EQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP-GEKGNRGVPGMPGLKGLKGLPGPAG-- 991 Query: 627 RPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----------QGLPRPQDMHGPQ 675 PPGP+G +G G P G G G MG G G G P +HG Q Sbjct: 992 -PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 676 GMQRHPGPH-----GPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG 730 G + PG GP GP G PG G G +G MG GPPG G GP+G PG G G Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 731 PQGPPGTQG---------------MQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGP 775 G PG G ++GPPG G G P P GI+G G GI GP + Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 776 LMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRG 835 GL ++ PPGPR N G G P P PG G RGP I G Sbjct: 1171 ETGL----LRAPPGPRGNPGAQGAKGDRGAPGF----PGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 836 MQGPPPQGSMLGPPQE-LRGPPGSQSQQGPPQGSLGPPPQG--GMQGPPGPQGQQNPARG 892 GPP + P Q RGPPGS+ G P G GPP G++G G G P +G Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP-GPPGPPGSHVIGIKGDKGSMGHPGP-KG 1280 Query: 893 PHPSQG----PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGL-GQQGAQGRIPPLN 947 P + G P TP L GPR +G PG+ G++G G + + Sbjct: 1281 PPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQG--------FPGVKGEKGNPGFLGSIG 1331 Query: 948 PGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHP 1007 P GP +GPP P + + G P GP P G +G P GP Sbjct: 1332 PPGPIGP-----KGPPGVRGDPGTLKIISLPGSP--GPPGTPGEPGM--QGEPGPPGP-- 1380 Query: 1008 DFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGR 1067 P + P G ++ + G P P EK +G G P P G+ Sbjct: 1381 --------PGNLGPCGPRGKPGKDGKP-GTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGK 1431 Query: 1068 GAARGPPGAWEGR 1080 G P W R Sbjct: 1432 RGDSGSPATWTTR 1444 Score = 179 bits (454), Expect = 2e-44 Identities = 256/916 (27%), Positives = 318/916 (34%), Gaps = 185/916 (20%) Query: 547 TLQYTNPQLLEQLKIERLAQKQVEQIQ-----PPPSSGTPLLGPQPFPGQGPMSQIPQGF 601 TL Y LK ++ A + E I+ P G P GPQ PG P GF Sbjct: 140 TLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP--GPQGLPG-------PPGF 190 Query: 602 QQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPL-----HQGGGGPQGFMGPQ 656 P +GPPGP G F PG G GP+G H+G G +G GP Sbjct: 191 PGP------------VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 238 Query: 657 GPQGP-------------------------------PQGLP-----RPQDMHGPQGMQRH 680 GP G P GLP + G G+Q Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGK 298 Query: 681 PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGM 740 PG G G G G +G+ G G MG G G +G IGP G GP + G +G Sbjct: 299 PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358 Query: 741 QGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGP--LMGL-NPRGMQGPPGPRENQGPA 797 GPPGPRG +GP P G G PGS G P +G GL +G +G PG P Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418 Query: 798 PQGMIMGHP--PQEMRGPHPPGGLL-------GHGPQEMRGPQEIRGMQGPPPQGSML-- 846 G G P P P PPG ++ HG G I G+ GP + +L Sbjct: 419 SPG-CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 847 ------GPPQELRGPPGSQSQQGPP--------QGSLGPPPQGGMQGPPG-PQGQQNPAR 891 GPP L G PG +G P +GS G P G+ G PG P Q +P Sbjct: 478 QCPYIPGPP-GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536 Query: 892 GPHPSQGPIPFQQQKTPLLGD-GPRAPFNQEGQSTGP-PPLIPGL----------GQQGA 939 + P Q P GD G R ++G P P + GL G++G Sbjct: 537 KGEKGETLQPEGQVGVP--GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594 Query: 940 QGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQS-------GGPEHGPERG---- 988 QG PP +PG P GPP + GP E + + G P RG Sbjct: 595 QG--PPGDPGSPGSPGPAGPAGPPGY--GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV 650 Query: 989 --PFRGGQDCRGPPDRRGPH--PDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEK 1044 P G GPP GP P P + D G GP + Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD--------------PGLPGPDGEPGI 696 Query: 1045 WRRGGPGPPFPPDHREF--SEGD-------GRGAARGPPGAWEGRRPGDERFPRDPEDPR 1095 G PGPP P + F ++G G G PG + P P P Sbjct: 697 PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756 Query: 1096 FRGRREESFRRG-----------APPRHEGRAPPRGRDGFPGPE-DFGPEENFDASEEAA 1143 F G R S G P +EG PRG G PGP + GP A Sbjct: 757 FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816 Query: 1144 RGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPG-PGHE-HFRDTPRP 1201 +G L G + GR+G P P G + PG PGH+ + Sbjct: 817 QG--LPGLNGLKGQQGRRG-KTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873 Query: 1202 DHPPHDG-HSPASRERSSSLQGMDMASLPPRKRPWHDG-------PGTSEHREMEAPGGP 1253 +P + G P + + G A PP P + G PG + G Sbjct: 874 GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP-PGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 1254 SEDRGGKGRGGPGPAQRVPKSGRSSSLDG-EHHDGYHRDEPFGGPPG----SGTPSRGGR 1308 ++G KG GP V L G + G + G PG G P G Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 1309 SGSNWGRGSNMNSGPP 1324 G GS N G P Sbjct: 993 PGPRGDLGSTGNPGEP 1008 Score = 164 bits (416), Expect = 4e-40 Identities = 229/811 (28%), Positives = 290/811 (35%), Gaps = 175/811 (21%) Query: 630 GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----------QGLPRPQDMHGPQGMQ 678 G +G GP G P +G GP+G GPQGP+G P +G+ G G+ Sbjct: 49 GEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLP 108 Query: 679 RHPGPHGPLGPQGPPGPQGSSGPQGH------MGPQGPPGPQGHIGPQGPPGPQ------ 726 PG GP G G PG GS G QG +G G PG G G +G P + Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168 Query: 727 --GHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ------GPLMG 778 G G G PG QG+ GPPG G GPP P G G PG+ G +GP G Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGE 228 Query: 779 LNPRGMQGPPGPREN-----QGPAPQGMIMGHPPQE--MRGPHPPG--GLLGHGPQEMRG 829 +G+ GPPGP GP + + G + M P PPG GL G +G Sbjct: 229 RGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKG 288 Query: 830 PQEIRGMQGPPPQGSMLGPP-----QELRGPPGSQSQQG--PPQGSLGPP---------- 872 G+QG P + + G P + RG PG + G +G +GPP Sbjct: 289 APGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYD 348 Query: 873 -----PQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGP 927 G GPPGP+G ARGP GP P +P + G Sbjct: 349 TYQEKGDEGTPGPPGPRG----ARGPQGPSGP-----------PGVPGSPGSSRPGLRGA 393 Query: 928 PPLIPGL-GQQGAQGRI------PPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGG 980 P PGL G +G +GR P +PG P S GPP GP + + Sbjct: 394 PGW-PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP----GPPGDIVFRKGPP 448 Query: 981 PEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLP 1040 +HG G G P GP +G G L Sbjct: 449 GDHG-----LPGYLGSPGIPGVDGP---------------------------KGEPGLLC 476 Query: 1041 QEEKWRRGGPGPPFPPDHREFSEGDGR-GAA--RGPPGA-WEGRRPGDERFPRDPEDPRF 1096 + + G PG P P GR GAA +G PG+ PG FP DP Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536 Query: 1097 RGRREESFRR----GAP--PRHEGRAPPRGRDGFPGPEDF----GPEENFDAS-EEAARG 1145 +G + E+ + G P P G+ +G DG PG GP+ S E+ +G Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596 Query: 1146 RDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRK-----PDSWDGNREPGPGHEHFRDTPR 1200 G+P G G P P+ E G + P + E GP E TP Sbjct: 597 PPGDPGSPGSP--GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654 Query: 1201 PDHPPHDGHSPASRERSSSLQGM--DMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRG 1258 P P G P G+ + P DG P GP D+G Sbjct: 655 PGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 Query: 1259 GKGRGG----PG-------------------PAQRVPKSGRSSSLDGEH-HDGYHRDEPF 1294 G G PG PA +P + GE + G H + Sbjct: 713 FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772 Query: 1295 GGPPG-SGTPSRGGRSGSNWGRGSNMNSGPP 1324 G PG GTP G G + RG GPP Sbjct: 773 PGLPGLPGTP---GNEGLDGPRGDPGQPGPP 800 Score = 146 bits (369), Expect = 1e-34 Identities = 207/719 (28%), Positives = 257/719 (35%), Gaps = 100/719 (13%) Query: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQ 741 G G G +G PGP GS G +G GP+G PGPQG G G PG G G +G G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 742 GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMG-LNPRGMQGPPGPRENQG-PAPQ 799 G PG G G P+G+ G PG G +G L G L G+ G G + +G PA + Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 800 GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQEL--RGPPG 857 I E+ PG GPQ + GP G GPP G P + RGP G Sbjct: 163 EDI------ELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216 Query: 858 SQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD-GPRA 916 ++ G G G+ GPPGP G ++ + ++ +G+ GP Sbjct: 217 HMGER--VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Query: 917 PFNQEGQSTGP---PPLIPGL-------------GQQGAQGR--IPPLNPGQGPGPNKGD 958 P G+S G P PGL G +G +G P L G KGD Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334 Query: 959 SRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDD 1018 GPP GP Q G E P GP G + RGP GP P P P Sbjct: 335 I-GPPGFR-GPTEYYDTYQEKGDEGTP--GP-PGPRGARGPQGPSGP-PGVP---GSPGS 385 Query: 1019 FHPDKRFGHRLREFEGR---------------GGPLPQEEKWRRGGPGPPFPPDHREFSE 1063 P R +G G P G PGPP PP F + Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445 Query: 1064 G----------------DGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRG 1107 G G +G PG + P P P P G + R+G Sbjct: 446 GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505 Query: 1108 APPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGR-GTP-----RG--G 1159 A P G G PG F P D + +G L+ G+ G P RG G Sbjct: 506 AAGLKGSPGSP-GNTGLPGFPGF-PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563 Query: 1160 RKGL-----LPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPP-HDGHSPAS 1213 RKGL P P +G G++ P PG +P P P G+ P Sbjct: 564 RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQG 622 Query: 1214 RERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPK 1273 QG+ A PP + GP PG P G G GP +P Sbjct: 623 EPGLQGTQGVPGAPGPPGEA----GPRGELSVSTPVPGPPGPP-GPPGHPGPQGPPGIPG 677 Query: 1274 S-GRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 S G+ DG EP G PG G P G G G+ + G P + G Sbjct: 678 SLGKCGDPGLPGPDG----EP--GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 204 bits (520), Expect = 4e-52 Identities = 277/903 (30%), Positives = 340/903 (37%), Gaps = 199/903 (22%) Query: 574 PPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQFRPPGP-Q 632 PP G+P P P GP PQG +Q +P G GP+G+ P Sbjct: 597 PPGDPGSPG-SPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP 655 Query: 633 GQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGMQRHPGPHGPLGPQGP 692 G GP GPP H G GP G G G G P GLP P G G+ PGP GP G QG Sbjct: 656 GPPGPPGPPGHPGPQGPPGIPGSLGKCGDP-GLPGPDGEPGIPGIG-FPGPPGPKGDQGF 713 Query: 693 PGPQGSSGPQGHMGPQGPPGPQGHIG---------PQGP-----PGPQGHLGPQGP---- 734 PG +GS G G MG G PG G G P GP PG +G+ G G Sbjct: 714 PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLP 773 Query: 735 -----PGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPG 789 PGT G +G GPRG G P P G QG PG + I+GP L GLN G++G G Sbjct: 774 GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLN--GLKGQQG 830 Query: 790 PRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGH----GPQEMRGPQEIRGMQGPPPQGS- 844 R GP I G G G+ GH GP RG G+ GPP + Sbjct: 831 RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGV 890 Query: 845 --MLGPPQELRGPPGSQSQQGPP--QGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQ--- 897 M+G P + GPPG G P +GS G P G +G PG +G+Q P PS+ Sbjct: 891 IGMMGFPGAI-GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 898 ----------------------GPIPFQQQKTPLLG-DGPRAPFNQEGQ--STGPPPL-- 930 +P L G GP P G STG P Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 931 ---IPG----LGQQGAQGR--------------IPPLNPGQG----PGPNKGDSRGPPNH 965 IPG +G G++G+ +P ++ QG PG ++G GPP Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069 Query: 966 --------HMGPMSERRHEQSGGPEH----GPERGPFRGGQDCRGPPDRRGPHPDFPDDF 1013 MG E Q G P H GPE P G G P + GPH D Sbjct: 1070 TGDPGLPGDMGKKGEMG--QPGPPGHLGPAGPEGAP--GSPGSPGLPGKPGPHGDLGFKG 1125 Query: 1014 SRPDDFHPDKRFGHRLREFEGRGGPLP-QEEKWRRGGPGPPFPPDHREFSEGDGRGAARG 1072 + P R L F G GP+ + ++ R G PGP E G R Sbjct: 1126 IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPA--------GEKGETGLLRA 1177 Query: 1073 PPG-----AWEGRRPGDERFPRDPEDPRFRGRREESFRRG--------APPRHEG----- 1114 PPG +G + GD P P P +G ++ RG PP G Sbjct: 1178 PPGPRGNPGAQGAK-GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236 Query: 1115 ----RAPP--RGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRG---------- 1158 R PP RG G PGP GP + + +G G P+G Sbjct: 1237 QTGNRGPPGSRGSPGAPGPP--GPPGSHVIGIKGDKG----SMGHPGPKGPPGTAGDMGP 1290 Query: 1159 -GRKGL-----LPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPA 1212 GR G LP P P F+G GN PG F + P P P Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGN----PG---FLGSIGPPGPIGPKGPPG 1343 Query: 1213 SRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGP-GPAQRV 1271 R +L+ + SLP P PGT M+ GP G G GP GP + Sbjct: 1344 VRGDPGTLK---IISLPGSPGP----PGTPGEPGMQGEPGPP---GPPGNLGPCGPRGKP 1393 Query: 1272 PKSGRSSSLD--GEHHDGYHRDEPFGGPPGS-GTPSRGGRSGSNWGRGSNMNSGPPRRGA 1328 K G+ + GE + + EP GP GS G P G+ G +SG P Sbjct: 1394 GKDGKPGTPGPAGEKGNKGSKGEP--GPAGSDGLPGLKGKRG---------DSGSPATWT 1442 Query: 1329 SRG 1331 +RG Sbjct: 1443 TRG 1445 Score = 200 bits (509), Expect = 7e-51 Identities = 234/774 (30%), Positives = 284/774 (36%), Gaps = 162/774 (20%) Query: 618 GPPGPQGQFRPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGLPRPQDMHGPQGM 677 G PGP+G+ G +G GP G P G G GP GP GPP +GPQG Sbjct: 578 GLPGPKGELALSGEKGDQGPPGDP------GSPGSPGPAGPAGPPG--------YGPQG- 622 Query: 678 QRHPGPHGPLGPQGPPGPQGSSGPQGHM-------GPQGPPGPQGHIGPQGPPGPQGHLG 730 PG G G G PGP G +GP+G + GP GPPGP GH GPQGPPG G LG Sbjct: 623 --EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLG 680 Query: 731 PQGPPGTQGMQGPPGPRGM--QGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPP 788 G PG G G PG G+ GPP P G QG PG++G G + GL G G P Sbjct: 681 KCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLP--GKPGLP 738 Query: 789 GPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPP--PQGSML 846 G + A G GP PG G G + G+ G P P L Sbjct: 739 GAKGEPAVAMPG-----------GPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 847 GPPQELRGPPGSQSQQGPP-------QGSLGPPPQGGMQGPPGPQGQQNPARGPHP---S 896 P+ G PG +QGPP +G+ G P G++G G +G+ P P Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 897 QGPIPFQQQKTPLLG-DGPRAPFNQEGQSTGP----PPLIPG-LGQQGAQGRI----PPL 946 + P + + G G P Q G P PP G +G G G I PP Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 947 NPGQ-----GPG-PNKGDSRGPP-----------------NHHMGPMSERRHEQ-SGGPE 982 NPG PG P RG P +H +G E + +G P Sbjct: 908 NPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 983 HGPERGP--FRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLP 1040 RG G + +G P GP D S + P LR G G + Sbjct: 968 EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG------LRGIPGSMGNMG 1021 Query: 1041 QE-EKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGR 1099 K +RG G P G +G PG EG RPG DP P G+ Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGK 1081 Query: 1100 REESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPRG- 1158 + E + G PP H G A P G G PG G+ P G Sbjct: 1082 KGEMGQPG-PPGHLGPAGPEGAPGSPGSPGLP--------------------GKPGPHGD 1120 Query: 1159 ----GRKGLLPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPPHDGHSPASR 1214 G KGLL P G R P PG F +P P D Sbjct: 1121 LGFKGIKGLLGPP----------------GIRGP-PGLPGFPGSPGPMGIRGD------- 1156 Query: 1215 ERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPK- 1273 QG D P ++ E + AP GP + G +G G A P Sbjct: 1157 ------QGRDGIPGPAGEK--------GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202 Query: 1274 SGRSSSLDGEHHDGYHRDEPFGGPPG---SGTPSRGGRSGSNWGRGSNMNSGPP 1324 GR ++ G E F GPPG + P + G G RGS GPP Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Score = 179 bits (455), Expect = 1e-44 Identities = 175/553 (31%), Positives = 218/553 (39%), Gaps = 82/553 (14%) Query: 567 KQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQF 626 +Q ++ P PS + ++G + PG + P G + MP G PGP G Sbjct: 935 EQGDKGNPGPSEISHVIGDKGEPGLKGFAGNP-GEKGNRGVPGMPGLKGLKGLPGPAG-- 991 Query: 627 RPPGPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----------QGLPRPQDMHGPQ 675 PPGP+G +G G P G G G MG G G G P +HG Q Sbjct: 992 -PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQ 1050 Query: 676 GMQRHPGPH-----GPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLG 730 G + PG GP GP G PG G G +G MG GPPG G GP+G PG G G Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110 Query: 731 PQGPPGTQG---------------MQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGP 775 G PG G ++GPPG G G P P GI+G G GI GP + Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170 Query: 776 LMGLNPRGMQGPPGPRENQGPAPQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRG 835 GL ++ PPGPR N G G P P PG G RGP I G Sbjct: 1171 ETGL----LRAPPGPRGNPGAQGAKGDRGAPGF----PGLPGRKGAMGDAGPRGPTGIEG 1222 Query: 836 MQGPPPQGSMLGPPQE-LRGPPGSQSQQGPPQGSLGPPPQG--GMQGPPGPQGQQNPARG 892 GPP + P Q RGPPGS+ G P G GPP G++G G G P +G Sbjct: 1223 FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP-GPPGPPGSHVIGIKGDKGSMGHPGP-KG 1280 Query: 893 PHPSQG----PIPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGL-GQQGAQGRIPPLN 947 P + G P TP L GPR +G PG+ G++G G + + Sbjct: 1281 PPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQG--------FPGVKGEKGNPGFLGSIG 1331 Query: 948 PGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHP 1007 P GP +GPP P + + G P GP P G +G P GP Sbjct: 1332 PPGPIGP-----KGPPGVRGDPGTLKIISLPGSP--GPPGTPGEPGM--QGEPGPPGP-- 1380 Query: 1008 DFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEKWRRGGPGPPFPPDHREFSEGDGR 1067 P + P G ++ + G P P EK +G G P P G+ Sbjct: 1381 --------PGNLGPCGPRGKPGKDGKP-GTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGK 1431 Query: 1068 GAARGPPGAWEGR 1080 G P W R Sbjct: 1432 RGDSGSPATWTTR 1444 Score = 179 bits (454), Expect = 2e-44 Identities = 256/916 (27%), Positives = 318/916 (34%), Gaps = 185/916 (20%) Query: 547 TLQYTNPQLLEQLKIERLAQKQVEQIQ-----PPPSSGTPLLGPQPFPGQGPMSQIPQGF 601 TL Y LK ++ A + E I+ P G P GPQ PG P GF Sbjct: 140 TLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP--GPQGLPG-------PPGF 190 Query: 602 QQPHPSQQMPMNMAQMGPPGPQGQFRPPGPQGQMGPQGPPL-----HQGGGGPQGFMGPQ 656 P +GPPGP G F PG G GP+G H+G G +G GP Sbjct: 191 PGP------------VGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 238 Query: 657 GPQGP-------------------------------PQGLP-----RPQDMHGPQGMQRH 680 GP G P GLP + G G+Q Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGK 298 Query: 681 PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGM 740 PG G G G G +G+ G G MG G G +G IGP G GP + G +G Sbjct: 299 PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358 Query: 741 QGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGP--LMGL-NPRGMQGPPGPRENQGPA 797 GPPGPRG +GP P G G PGS G P +G GL +G +G PG P Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418 Query: 798 PQGMIMGHP--PQEMRGPHPPGGLL-------GHGPQEMRGPQEIRGMQGPPPQGSML-- 846 G G P P P PPG ++ HG G I G+ GP + +L Sbjct: 419 SPG-CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 847 ------GPPQELRGPPGSQSQQGPP--------QGSLGPPPQGGMQGPPG-PQGQQNPAR 891 GPP L G PG +G P +GS G P G+ G PG P Q +P Sbjct: 478 QCPYIPGPP-GLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536 Query: 892 GPHPSQGPIPFQQQKTPLLGD-GPRAPFNQEGQSTGP-PPLIPGL----------GQQGA 939 + P Q P GD G R ++G P P + GL G++G Sbjct: 537 KGEKGETLQPEGQVGVP--GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594 Query: 940 QGRIPPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQS-------GGPEHGPERG---- 988 QG PP +PG P GPP + GP E + + G P RG Sbjct: 595 QG--PPGDPGSPGSPGPAGPAGPPGY--GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV 650 Query: 989 --PFRGGQDCRGPPDRRGPH--PDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQEEK 1044 P G GPP GP P P + D G GP + Sbjct: 651 STPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGD--------------PGLPGPDGEPGI 696 Query: 1045 WRRGGPGPPFPPDHREF--SEGD-------GRGAARGPPGAWEGRRPGDERFPRDPEDPR 1095 G PGPP P + F ++G G G PG + P P P Sbjct: 697 PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756 Query: 1096 FRGRREESFRRG-----------APPRHEGRAPPRGRDGFPGPE-DFGPEENFDASEEAA 1143 F G R S G P +EG PRG G PGP + GP A Sbjct: 757 FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816 Query: 1144 RGRDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRKPDSWDGNREPG-PGHE-HFRDTPRP 1201 +G L G + GR+G P P G + PG PGH+ + Sbjct: 817 QG--LPGLNGLKGQQGRRG-KTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQR 873 Query: 1202 DHPPHDG-HSPASRERSSSLQGMDMASLPPRKRPWHDG-------PGTSEHREMEAPGGP 1253 +P + G P + + G A PP P + G PG + G Sbjct: 874 GYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP-PGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 1254 SEDRGGKGRGGPGPAQRVPKSGRSSSLDG-EHHDGYHRDEPFGGPPG----SGTPSRGGR 1308 ++G KG GP V L G + G + G PG G P G Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 1309 SGSNWGRGSNMNSGPP 1324 G GS N G P Sbjct: 993 PGPRGDLGSTGNPGEP 1008 Score = 164 bits (416), Expect = 4e-40 Identities = 229/811 (28%), Positives = 290/811 (35%), Gaps = 175/811 (21%) Query: 630 GPQGQMGPQGPPLHQGGGGPQGFMGPQGPQGPP-----------QGLPRPQDMHGPQGMQ 678 G +G GP G P +G GP+G GPQGP+G P +G+ G G+ Sbjct: 49 GEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLP 108 Query: 679 RHPGPHGPLGPQGPPGPQGSSGPQGH------MGPQGPPGPQGHIGPQGPPGPQ------ 726 PG GP G G PG GS G QG +G G PG G G +G P + Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168 Query: 727 --GHLGPQGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQ------GPLMG 778 G G G PG QG+ GPPG G GPP P G G PG+ G +GP G Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGE 228 Query: 779 LNPRGMQGPPGPREN-----QGPAPQGMIMGHPPQE--MRGPHPPG--GLLGHGPQEMRG 829 +G+ GPPGP GP + + G + M P PPG GL G +G Sbjct: 229 RGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKG 288 Query: 830 PQEIRGMQGPPPQGSMLGPP-----QELRGPPGSQSQQG--PPQGSLGPP---------- 872 G+QG P + + G P + RG PG + G +G +GPP Sbjct: 289 APGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYD 348 Query: 873 -----PQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGDGPRAPFNQEGQSTGP 927 G GPPGP+G ARGP GP P +P + G Sbjct: 349 TYQEKGDEGTPGPPGPRG----ARGPQGPSGP-----------PGVPGSPGSSRPGLRGA 393 Query: 928 PPLIPGL-GQQGAQGRI------PPLNPGQGPGPNKGDSRGPPNHHMGPMSERRHEQSGG 980 P PGL G +G +GR P +PG P S GPP GP + + Sbjct: 394 PGW-PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP----GPPGDIVFRKGPP 448 Query: 981 PEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLP 1040 +HG G G P GP +G G L Sbjct: 449 GDHG-----LPGYLGSPGIPGVDGP---------------------------KGEPGLLC 476 Query: 1041 QEEKWRRGGPGPPFPPDHREFSEGDGR-GAA--RGPPGA-WEGRRPGDERFPRDPEDPRF 1096 + + G PG P P GR GAA +G PG+ PG FP DP Sbjct: 477 TQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGL 536 Query: 1097 RGRREESFRR----GAP--PRHEGRAPPRGRDGFPGPEDF----GPEENFDAS-EEAARG 1145 +G + E+ + G P P G+ +G DG PG GP+ S E+ +G Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596 Query: 1146 RDLRGRGRGTPRGGRKGLLPTPDEFPRFEGGRK-----PDSWDGNREPGPGHEHFRDTPR 1200 G+P G G P P+ E G + P + E GP E TP Sbjct: 597 PPGDPGSPGSP--GPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654 Query: 1201 PDHPPHDGHSPASRERSSSLQGM--DMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRG 1258 P P G P G+ + P DG P GP D+G Sbjct: 655 PGPPGPPG--PPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 Query: 1259 GKGRGG----PG-------------------PAQRVPKSGRSSSLDGEH-HDGYHRDEPF 1294 G G PG PA +P + GE + G H + Sbjct: 713 FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772 Query: 1295 GGPPG-SGTPSRGGRSGSNWGRGSNMNSGPP 1324 G PG GTP G G + RG GPP Sbjct: 773 PGLPGLPGTP---GNEGLDGPRGDPGQPGPP 800 Score = 146 bits (369), Expect = 1e-34 Identities = 207/719 (28%), Positives = 257/719 (35%), Gaps = 100/719 (13%) Query: 682 GPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQ 741 G G G +G PGP GS G +G GP+G PGPQG G G PG G G +G G G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 742 GPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMG-LNPRGMQGPPGPRENQG-PAPQ 799 G PG G G P+G+ G PG G +G L G L G+ G G + +G PA + Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162 Query: 800 GMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQEL--RGPPG 857 I E+ PG GPQ + GP G GPP G P + RGP G Sbjct: 163 EDI------ELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216 Query: 858 SQSQQGPPQGSLGPPPQGGMQGPPGPQGQQNPARGPHPSQGPIPFQQQKTPLLGD-GPRA 916 ++ G G G+ GPPGP G ++ + ++ +G+ GP Sbjct: 217 HMGER--VIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Query: 917 PFNQEGQSTGP---PPLIPGL-------------GQQGAQGR--IPPLNPGQGPGPNKGD 958 P G+S G P PGL G +G +G P L G KGD Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334 Query: 959 SRGPPNHHMGPMSERRHEQSGGPEHGPERGPFRGGQDCRGPPDRRGPHPDFPDDFSRPDD 1018 GPP GP Q G E P GP G + RGP GP P P P Sbjct: 335 I-GPPGFR-GPTEYYDTYQEKGDEGTP--GP-PGPRGARGPQGPSGP-PGVP---GSPGS 385 Query: 1019 FHPDKRFGHRLREFEGR---------------GGPLPQEEKWRRGGPGPPFPPDHREFSE 1063 P R +G G P G PGPP PP F + Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445 Query: 1064 G----------------DGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESFRRG 1107 G G +G PG + P P P P G + R+G Sbjct: 446 GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505 Query: 1108 APPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGR-GTP-----RG--G 1159 A P G G PG F P D + +G L+ G+ G P RG G Sbjct: 506 AAGLKGSPGSP-GNTGLPGFPGF-PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563 Query: 1160 RKGL-----LPTPDEFPRFEGGRKPDSWDGNREPGPGHEHFRDTPRPDHPP-HDGHSPAS 1213 RKGL P P +G G++ P PG +P P P G+ P Sbjct: 564 RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP-PGDPGSPGSPGPAGPAGPPGYGPQG 622 Query: 1214 RERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPAQRVPK 1273 QG+ A PP + GP PG P G G GP +P Sbjct: 623 EPGLQGTQGVPGAPGPPGEA----GPRGELSVSTPVPGPPGPP-GPPGHPGPQGPPGIPG 677 Query: 1274 S-GRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPPRRGASRG 1331 S G+ DG EP G PG G P G G G+ + G P + G Sbjct: 678 SLGKCGDPGLPGPDG----EP--GIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.139 0.452 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,222,498 Number of Sequences: 37866 Number of extensions: 7102307 Number of successful extensions: 123720 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 674 Number of HSP's successfully gapped in prelim test: 2152 Number of HSP's that attempted gapping in prelim test: 22519 Number of HSP's gapped (non-prelim): 20110 length of query: 1336 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1222 effective length of database: 13,930,794 effective search space: 17023430268 effective search space used: 17023430268 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.