Guide to the Human Genome
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Search of human proteins with 56181387

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
sapiens]
         (303 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|56181387 STIP1 homology and U-box containing protein 1 [Homo ...   617   e-177
gi|24308141 small glutamine-rich tetratricopeptide repeat (TPR)-...    75   7e-14
gi|29725607 smooth muscle cell associated protein-1 isoform 2 [H...    69   5e-12
gi|21361356 translocase of outer mitochondrial membrane 34 [Homo...    68   9e-12
gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]          67   1e-11
gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]       67   3e-11
gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]          66   4e-11
gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizi...    64   1e-10
gi|54607135 translocase of outer mitochondrial membrane 70 homol...    64   1e-10
gi|89179321 smooth muscle cell associated protein-1 isoform 3 [H...    64   1e-10
gi|27262638 sperm associated antigen 1 [Homo sapiens]                  64   1e-10
gi|27262636 sperm associated antigen 1 [Homo sapiens]                  64   1e-10
gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]     64   2e-10
gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform...    63   4e-10
gi|225735593 RNA polymerase II associated protein 3 isoform 2 [H...    59   4e-09
gi|225735591 RNA polymerase II associated protein 3 isoform 1 [H...    59   4e-09
gi|73747840 LON peptidase N-terminal domain and ring finger 3 is...    59   4e-09
gi|225735595 RNA polymerase II associated protein 3 isoform 3 [H...    59   7e-09
gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform...    59   7e-09
gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]       58   9e-09
gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]       58   9e-09
gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Hom...    57   2e-08
gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]     57   2e-08
gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]          55   1e-07
gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]          55   1e-07
gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]            55   1e-07
gi|4503729 FK506 binding protein 52 [Homo sapiens]                     53   3e-07
gi|37622896 LON peptidase N-terminal domain and ring finger 3 is...    52   6e-07
gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]           51   1e-06
gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]           51   1e-06

>gi|56181387 STIP1 homology and U-box containing protein 1 [Homo
           sapiens]
          Length = 303

 Score =  617 bits (1590), Expect = e-177
 Identities = 303/303 (100%), Positives = 303/303 (100%)

Query: 1   MKGKEEKEGGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVA 60
           MKGKEEKEGGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVA
Sbjct: 1   MKGKEEKEGGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVA 60

Query: 61  VYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRA 120
           VYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRA
Sbjct: 61  VYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRA 120

Query: 121 YSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEEC 180
           YSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEEC
Sbjct: 121 YSLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEEC 180

Query: 181 QRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELM 240
           QRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELM
Sbjct: 181 QRNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELM 240

Query: 241 REPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWV 300
           REPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWV
Sbjct: 241 REPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGWV 300

Query: 301 EDY 303
           EDY
Sbjct: 301 EDY 303


>gi|24308141 small glutamine-rich tetratricopeptide repeat
           (TPR)-containing, beta [Homo sapiens]
          Length = 304

 Score = 75.1 bits (183), Expect = 7e-14
 Identities = 42/126 (33%), Positives = 65/126 (51%), Gaps = 5/126 (3%)

Query: 20  PEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQA 79
           PE    A +LK++GN       Y  A  CY +AI  +P  AVYY NRA    K+  +  A
Sbjct: 79  PEDVGKADQLKDEGNNHMKEENYAAAVDCYTQAIELDPNNAVYYCNRAAAQSKLGHYTDA 138

Query: 80  LADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSAL 139
           + DC +A+ +D +  KA+  +G     +  ++EA+ + Q+A  L  E      D   S L
Sbjct: 139 IKDCEKAIAIDSKYSKAYGRMGLALTALNKFEEAVTSYQKALDLDPE-----NDSYKSNL 193

Query: 140 RIAKKK 145
           +IA++K
Sbjct: 194 KIAEQK 199


>gi|29725607 smooth muscle cell associated protein-1 isoform 2 [Homo
           sapiens]
          Length = 944

 Score = 68.9 bits (167), Expect = 5e-12
 Identities = 48/157 (30%), Positives = 82/157 (52%), Gaps = 19/157 (12%)

Query: 15  AGGGSPEKSP------SAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLV---AVYYTN 65
           +G G+PE  P      S ++L+++GN LF    Y  A A Y +A+  +      AV + N
Sbjct: 4   SGPGTPEPRPATPGASSVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRN 63

Query: 66  RALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAK 125
           RA C+LK++ +++A  +  +A+E DG  VKA +   Q   ++   D+A+ +LQR  SL  
Sbjct: 64  RAACHLKLEDYDKAETEASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEP 123

Query: 126 EQRLNFGDDIPSALR-----IAKKKRWNSIEERRIHQ 157
           + ++        ALR     I +K R+ S  + ++ Q
Sbjct: 124 KNKV-----FQEALRNIGGQIQEKVRYMSSTDAKVEQ 155


>gi|21361356 translocase of outer mitochondrial membrane 34 [Homo
           sapiens]
          Length = 309

 Score = 68.2 bits (165), Expect = 9e-12
 Identities = 33/92 (35%), Positives = 56/92 (60%)

Query: 26  AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRR 85
           A+ LKE+GN L     + +A   Y  ++  + L +  Y+NRALCYL ++Q+ +A+ DC  
Sbjct: 193 ARVLKEEGNELVKKGNHKKAIEKYSESLLCSNLESATYSNRALCYLVLKQYTEAVKDCTE 252

Query: 86  ALELDGQSVKAHFFLGQCQLEMESYDEAIANL 117
           AL+LDG++VKA +   Q    ++ Y  + A++
Sbjct: 253 ALKLDGKNVKAFYRRAQAHKALKDYKSSFADI 284



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 51/170 (30%), Positives = 73/170 (42%), Gaps = 33/170 (19%)

Query: 19  SPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAI-------TRNP-LVAVYYTNRALCY 70
           +P+   S +EL+  GN  F   +Y EA+A YGRA+       + +P   +V Y+NRA C+
Sbjct: 2   APKFPDSVEELRAAGNESFRNGQYAEASALYGRALRVLQAQGSSDPEEESVLYSNRAACH 61

Query: 71  LKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYD------------------- 111
           LK       + DC  AL L   S+K           +E Y                    
Sbjct: 62  LKDGNCRDCIKDCTSALALVPFSIKPLLRRASAYEALEKYPMAYVDYKTVLQIDDNVTSA 121

Query: 112 -EAIANLQRAY--SLAKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQE 158
            E I  + RA   SL  E RL     IP  + ++ +KRWNS+     H+E
Sbjct: 122 VEGINRMTRALMDSLGPEWRLKL-PSIP-LVPVSAQKRWNSLPSEN-HKE 168


>gi|90669931 tetratricopeptide repeat domain 12 [Homo sapiens]
          Length = 705

 Score = 67.4 bits (163), Expect = 1e-11
 Identities = 33/90 (36%), Positives = 50/90 (55%)

Query: 21  EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQAL 80
           E    A  LKE+GN  F    Y  A   Y   + +   + V YTNRA  Y+K++ +E+AL
Sbjct: 101 ENKVLADALKEKGNEAFAEGNYETAILRYSEGLEKLKDMKVLYTNRAQAYMKLEDYEKAL 160

Query: 81  ADCRRALELDGQSVKAHFFLGQCQLEMESY 110
            DC  AL+ D +  KA+F +G+  L +++Y
Sbjct: 161 VDCEWALKCDEKCTKAYFHMGKANLALKNY 190


>gi|4506921 small glutamine-rich tetratricopeptide [Homo sapiens]
          Length = 313

 Score = 66.6 bits (161), Expect = 3e-11
 Identities = 42/127 (33%), Positives = 63/127 (49%), Gaps = 5/127 (3%)

Query: 19  SPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQ 78
           S E S  A+ LK +GN       +  A   YG+AI  NP  AVY+ NRA  Y K+  +  
Sbjct: 84  SEEDSAEAERLKTEGNEQMKVENFEAAVHFYGKAIELNPANAVYFCNRAAAYSKLGNYAG 143

Query: 79  ALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSA 138
           A+ DC RA+ +D    KA+  +G     +  + EA+A  ++A  L  +      +   S 
Sbjct: 144 AVQDCERAICIDPAYSKAYGRMGLALSSLNKHVEAVAYYKKALELDPD-----NETYKSN 198

Query: 139 LRIAKKK 145
           L+IA+ K
Sbjct: 199 LKIAELK 205


>gi|22095349 WD and tetratricopeptide repeats 1 [Homo sapiens]
          Length = 676

 Score = 65.9 bits (159), Expect = 4e-11
 Identities = 43/130 (33%), Positives = 68/130 (52%), Gaps = 14/130 (10%)

Query: 21  EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQ---QHE 77
           E  P  + +K+Q N  F  +++ +A   Y +A+ R P  A+ Y NRA  Y+K +    H 
Sbjct: 356 ELPPYLERVKQQANEAFACQQWTQAIQLYSKAVQRAPHNAMLYGNRAAAYMKRKWDGDHY 415

Query: 78  QALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANL--------QRAYSLAKEQRL 129
            AL DC +A+ L+   +KAHF L +C  E++   EA+  L        ++A+S A +   
Sbjct: 416 DALRDCLKAISLNPCHLKAHFRLARCLFELKYVAEALECLDDFKGKFPEQAHSSACDA-- 473

Query: 130 NFGDDIPSAL 139
             G DI +AL
Sbjct: 474 -LGRDITAAL 482


>gi|5803181 stress-induced-phosphoprotein 1 (Hsp70/Hsp90-organizing
           protein) [Homo sapiens]
          Length = 543

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 47/157 (29%), Positives = 74/157 (47%), Gaps = 8/157 (5%)

Query: 26  AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRR 85
           A E K +GN  F    YP+A   Y  AI RNP  A  Y+NRA CY K+ + + AL DC  
Sbjct: 360 ALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYSNRAACYTKLLEFQLALKDCEE 419

Query: 86  ALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKK 145
            ++L+   +K +         M+ Y +A+   Q+A  L  +       D      +A+  
Sbjct: 420 CIQLEPTFIKGYTRKAAALEAMKDYTKAMDVYQKALDL--DSSCKEAADGYQRCMMAQYN 477

Query: 146 RWNSIEE--RRIHQESELHSYLS----RLIAAERERE 176
           R +S E+  RR   + E+   +S    RLI  + +++
Sbjct: 478 RHDSPEDVKRRAMADPEVQQIMSDPAMRLILEQMQKD 514



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 47/167 (28%), Positives = 73/167 (43%), Gaps = 14/167 (8%)

Query: 28  ELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRAL 87
           ELKE+GN+        +A  CY  AI  +P   V Y+NR+  Y K   +++A  D  + +
Sbjct: 6   ELKEKGNKALSVGNIDDALQCYSEAIKLDPHNHVLYSNRSAAYAKKGDYQKAYEDGCKTV 65

Query: 88  EL-----DGQSVKAHF--FLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALR 140
           +L      G S KA    FL + +    +Y+E + +      L KE   N         R
Sbjct: 66  DLKPDWGKGYSRKAAALEFLNRFEEAKRTYEEGLKHEANNPQL-KEGLQNM------EAR 118

Query: 141 IAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEECQRNHEGD 187
           +A++K  N      ++Q+ E       L++    REL E  RN   D
Sbjct: 119 LAERKFMNPFNMPNLYQKLESDPRTRTLLSDPTYRELIEQLRNKPSD 165



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 40/168 (23%), Positives = 71/168 (42%), Gaps = 23/168 (13%)

Query: 20  PEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQA 79
           PE    A + KE GN  +  + +  A   Y +A   +P    Y TN+A  Y +   + + 
Sbjct: 219 PENKKQALKEKELGNDAYKKKDFDTALKHYDKAKELDPTNMTYITNQAAVYFEKGDYNKC 278

Query: 80  LADCRRALELD-------GQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFG 132
              C +A+E+         Q  KA+  +G    + E Y +AI    +  SLA+ +     
Sbjct: 279 RELCEKAIEVGRENREDYRQIAKAYARIGNSYFKEEKYKDAIHFYNK--SLAEHR----- 331

Query: 133 DDIPSALRIAKKKRWNSIEERRIHQESELHSYLSRLIAAERERELEEC 180
              P  L+  +       +  +I +E E  +Y++  +A E + +  EC
Sbjct: 332 --TPDVLKKCQ-------QAEKILKEQERLAYINPDLALEEKNKGNEC 370


>gi|54607135 translocase of outer mitochondrial membrane 70 homolog
           A [Homo sapiens]
          Length = 608

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 55/234 (23%), Positives = 104/234 (44%), Gaps = 27/234 (11%)

Query: 4   KEEKEGGARLGAGGGSPEKSPS---------AQELKEQGNRLFVGRKYPEAAACYGRAIT 54
           ++  EG A    G G PE   +         AQ  K +GN+ F   KY +A  CY  AI+
Sbjct: 83  RKTPEGRASPAPGSGHPEGPGAHLDMNSLDRAQAAKNKGNKYFKAGKYEQAIQCYTEAIS 142

Query: 55  -----RNPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMES 109
                +N  ++ +Y NRA  + ++Q+ ++   DC +A+EL+ + VKA F   +   ++++
Sbjct: 143 LCPTEKNVDLSTFYQNRAAAFEQLQKWKEVAQDCTKAVELNPKYVKALFRRAKAHEKLDN 202

Query: 110 YDEAIANLQRAYSL---AKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYLS 166
             E + ++     L     +Q +   D +   L   K K      E  +     + SY S
Sbjct: 203 KKECLEDVTAVCILEGFQNQQSMLLADKVLKLLGKEKAKEKYKNREPLMPSPQFIKSYFS 262

Query: 167 R-----LIAAERERELEECQRNHEGD-----EDDSHVRAQQACIEAKHDKYMAD 210
                 +     + E  +  ++ EG+     E+  +++A+Q   E  +DK +++
Sbjct: 263 SFTDDIISQPMLKGEKSDEDKDKEGEALEVKENSGYLKAKQYMEEENYDKIISE 316



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 21/89 (23%), Positives = 47/89 (52%), Gaps = 1/89 (1%)

Query: 40  RKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQH-EQALADCRRALELDGQSVKAHF 98
           +++ +A   Y + I   P  A  Y ++ L  L+ +Q  ++ L    +A+E+D +   A+ 
Sbjct: 490 QQFGKADEMYDKCIDLEPDNATTYVHKGLLQLQWKQDLDRGLELISKAIEIDNKCDFAYE 549

Query: 99  FLGQCQLEMESYDEAIANLQRAYSLAKEQ 127
            +G  +++  + ++AI    +A +LAK +
Sbjct: 550 TMGTIEVQRGNMEKAIDMFNKAINLAKSE 578


>gi|89179321 smooth muscle cell associated protein-1 isoform 3 [Homo
           sapiens]
          Length = 929

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 43/141 (30%), Positives = 75/141 (53%), Gaps = 13/141 (9%)

Query: 25  SAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLV---AVYYTNRALCYLKMQQHEQALA 81
           S ++L+++GN LF    Y  A A Y +A+  +      AV + NRA C+LK++ +++A  
Sbjct: 5   SVEQLRKEGNELFKCGDYGGALAAYTQALGLDATPQDQAVLHRNRAACHLKLEDYDKAET 64

Query: 82  DCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALR- 140
           +  +A+E DG  VKA +   Q   ++   D+A+ +LQR  SL  + ++        ALR 
Sbjct: 65  EASKAIEKDGGDVKALYRRSQALEKLGRLDQAVLDLQRCVSLEPKNKV-----FQEALRN 119

Query: 141 ----IAKKKRWNSIEERRIHQ 157
               I +K R+ S  + ++ Q
Sbjct: 120 IGGQIQEKVRYMSSTDAKVEQ 140


>gi|27262638 sperm associated antigen 1 [Homo sapiens]
          Length = 926

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 33/95 (34%), Positives = 53/95 (55%)

Query: 29  LKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALE 88
           LKE+GN+    + Y +A + Y   +  N      YTNRALCYLK+ Q E+A  DC +AL+
Sbjct: 626 LKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQ 685

Query: 89  LDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
           L   +VKA +        +++Y +++ +L +   L
Sbjct: 686 LADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILL 720



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 41/113 (36%), Positives = 54/113 (47%), Gaps = 10/113 (8%)

Query: 9   GGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITR-NPL-------VA 60
           GGA    GGG   ++P+   LK QGN LF   ++ EAA  Y  AI    P        ++
Sbjct: 430 GGATGHPGGGQGAENPAG--LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLS 487

Query: 61  VYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEA 113
           + Y+NRA CYLK       + DC RALEL   S+K           +E Y +A
Sbjct: 488 ILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKA 540



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 60/211 (28%), Positives = 81/211 (38%), Gaps = 26/211 (12%)

Query: 15  AGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQ 74
           AG    EK   A   KE+GN  F    Y EA   Y R+I+  P V V Y NRA   +K+Q
Sbjct: 198 AGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPTV-VAYNNRAQAEIKLQ 256

Query: 75  QHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDD 134
               A  DC + LEL+  +VKA               EA  +L +   +  +  L     
Sbjct: 257 NWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDL----- 311

Query: 135 IPSALRIAKKKRWNSIEERRIHQE--SELHSYLSRLIAAERERELEE---CQRNHE---G 186
                    KK  + +E    + E  SE  +   R++  E E   +E     R HE   G
Sbjct: 312 --------AKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGG 363

Query: 187 D----EDDSHVRAQQACIEAKHDKYMADMDE 213
           D    E     RA Q C+     K +    E
Sbjct: 364 DKKPAEPAGAARAAQPCVMGNIQKKLTGKAE 394


>gi|27262636 sperm associated antigen 1 [Homo sapiens]
          Length = 926

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 33/95 (34%), Positives = 53/95 (55%)

Query: 29  LKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALE 88
           LKE+GN+    + Y +A + Y   +  N      YTNRALCYLK+ Q E+A  DC +AL+
Sbjct: 626 LKEEGNQCVNDKNYKDALSKYSECLKINNKECAIYTNRALCYLKLCQFEEAKQDCDQALQ 685

Query: 89  LDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
           L   +VKA +        +++Y +++ +L +   L
Sbjct: 686 LADGNVKAFYRRALAHKGLKNYQKSLIDLNKVILL 720



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 41/113 (36%), Positives = 54/113 (47%), Gaps = 10/113 (8%)

Query: 9   GGARLGAGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITR-NPL-------VA 60
           GGA    GGG   ++P+   LK QGN LF   ++ EAA  Y  AI    P        ++
Sbjct: 430 GGATGHPGGGQGAENPAG--LKSQGNELFRSGQFAEAAGKYSAAIALLEPAGSEIADDLS 487

Query: 61  VYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEA 113
           + Y+NRA CYLK       + DC RALEL   S+K           +E Y +A
Sbjct: 488 ILYSNRAACYLKEGNCSGCIQDCNRALELHPFSMKPLLRRAMAYETLEQYGKA 540



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 60/211 (28%), Positives = 81/211 (38%), Gaps = 26/211 (12%)

Query: 15  AGGGSPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQ 74
           AG    EK   A   KE+GN  F    Y EA   Y R+I+  P V V Y NRA   +K+Q
Sbjct: 198 AGLTEKEKDFLATREKEKGNEAFNSGDYEEAVMYYTRSISALPTV-VAYNNRAQAEIKLQ 256

Query: 75  QHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDD 134
               A  DC + LEL+  +VKA               EA  +L +   +  +  L     
Sbjct: 257 NWNSAFQDCEKVLELEPGNVKALLRRATTYKHQNKLREATEDLSKVLDVEPDNDL----- 311

Query: 135 IPSALRIAKKKRWNSIEERRIHQE--SELHSYLSRLIAAERERELEE---CQRNHE---G 186
                    KK  + +E    + E  SE  +   R++  E E   +E     R HE   G
Sbjct: 312 --------AKKTLSEVERDLKNSEAASETQTKGKRMVIQEIENSEDEEGKSGRKHEDGGG 363

Query: 187 D----EDDSHVRAQQACIEAKHDKYMADMDE 213
           D    E     RA Q C+     K +    E
Sbjct: 364 DKKPAEPAGAARAAQPCVMGNIQKKLTGKAE 394


>gi|5453958 protein phosphatase 5, catalytic subunit [Homo sapiens]
          Length = 499

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 34/96 (35%), Positives = 52/96 (54%), Gaps = 7/96 (7%)

Query: 26  AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRR 85
           A+ELK Q N  F  + Y  A   Y +AI  NP  A+YY NR+L YL+ + +  AL D  R
Sbjct: 28  AEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATR 87

Query: 86  ALELDGQSVKAHF-------FLGQCQLEMESYDEAI 114
           A+ELD + +K ++        LG+ +  +  Y+  +
Sbjct: 88  AIELDKKYIKGYYRRAASNMALGKFRAALRDYETVV 123


>gi|221219053 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 1
           [Homo sapiens]
          Length = 494

 Score = 62.8 bits (151), Expect = 4e-10
 Identities = 35/103 (33%), Positives = 52/103 (50%)

Query: 21  EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQAL 80
           E    A+  KEQGN  +  + Y EA   Y +AI   P  A YY NRA   + + +  +AL
Sbjct: 23  EAKREAETFKEQGNAYYAKKDYNEAYNYYTKAIDMCPKNASYYGNRAATLMMLGRFREAL 82

Query: 81  ADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
            D ++++ LD   V+ H   G+C L + +   A  + QRA  L
Sbjct: 83  GDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRSFQRALEL 125



 Score = 59.7 bits (143), Expect = 3e-09
 Identities = 48/200 (24%), Positives = 88/200 (44%), Gaps = 20/200 (10%)

Query: 30  KEQGNRLFVGRKYPEAAACYGRAITRNP----LVAVYYTNRALCYLKMQQHEQALADCRR 85
           KE GN+ F    Y  A   Y  A+  +P      A  Y NR     K+++ + A+ DC  
Sbjct: 260 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 319

Query: 86  ALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAK-EQRLNFGDDIPSALRIAKK 144
           A++LD   +KA+    QC ++ E Y+EA+ + ++ Y   K ++      +    LR +K+
Sbjct: 320 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELRKSKR 379

Query: 145 KRWNSIEERRIHQESELHSYLSRLIAAERERELEECQRNHEGDEDDSHVRAQQACIEAKH 204
           K +  I         + ++    +  A R+R L      H G           A ++ + 
Sbjct: 380 KDYYKI------LGVDKNASEDEIKKAYRKRALMHHPDRHSG---------ASAEVQKEE 424

Query: 205 DKYMADMDELFSQVDEKRKK 224
           +K   ++ E F+ + + +KK
Sbjct: 425 EKKFKEVGEAFTILSDPKKK 444


>gi|225735593 RNA polymerase II associated protein 3 isoform 2 [Homo
           sapiens]
          Length = 631

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 33/101 (32%), Positives = 52/101 (51%)

Query: 23  SPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALAD 82
           S  A  LKE+GN+ F   KY EA  CY + +  +P   V  TNRA  Y ++++   A +D
Sbjct: 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESD 189

Query: 83  CRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
           C  A+ L+    KA+   G  +  ++  +EA  + +R   L
Sbjct: 190 CNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLEL 230



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 32/84 (38%), Positives = 46/84 (54%)

Query: 30  KEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALEL 89
           K++GN  F   KY  A  CY R I  +   A+   NRA+ YLK+Q++E+A  DC +A+ L
Sbjct: 286 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 345

Query: 90  DGQSVKAHFFLGQCQLEMESYDEA 113
           DG   KA    G  +  +   +EA
Sbjct: 346 DGSYSKAFARRGTARTFLGKLNEA 369


>gi|225735591 RNA polymerase II associated protein 3 isoform 1 [Homo
           sapiens]
          Length = 665

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 33/101 (32%), Positives = 52/101 (51%)

Query: 23  SPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALAD 82
           S  A  LKE+GN+ F   KY EA  CY + +  +P   V  TNRA  Y ++++   A +D
Sbjct: 130 SQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESD 189

Query: 83  CRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
           C  A+ L+    KA+   G  +  ++  +EA  + +R   L
Sbjct: 190 CNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLEL 230



 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 32/84 (38%), Positives = 46/84 (54%)

Query: 30  KEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALEL 89
           K++GN  F   KY  A  CY R I  +   A+   NRA+ YLK+Q++E+A  DC +A+ L
Sbjct: 286 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 345

Query: 90  DGQSVKAHFFLGQCQLEMESYDEA 113
           DG   KA    G  +  +   +EA
Sbjct: 346 DGSYSKAFARRGTARTFLGKLNEA 369


>gi|73747840 LON peptidase N-terminal domain and ring finger 3
           isoform 1 [Homo sapiens]
          Length = 759

 Score = 59.3 bits (142), Expect = 4e-09
 Identities = 70/299 (23%), Positives = 113/299 (37%), Gaps = 36/299 (12%)

Query: 26  AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRR 85
           A +L+ +GNRL+  R+   A   Y  A+   P   + Y+NR+  Y  ++ HE AL D   
Sbjct: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302

Query: 86  ALELDGQSVKAHFFLGQCQLEMESYDEAIA----------------------NLQRAYSL 123
           A +L     KAHF   Q    +   +EA+                       NL+  +  
Sbjct: 303 ACKLRPMGFKAHFRKAQALATLGKVEEALREFLYCVSLDGKNKRARCEAQRDNLELPHCS 362

Query: 124 AKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSY--LSRLIAAERERELEECQ 181
           ++E+    GD   S+L    K + +  +     QE E   +   S   A+ +  + +E +
Sbjct: 363 SQEEAAARGDG--SSLMDPAKVKGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKK 420

Query: 182 RNHEGDEDDSHVRAQQACIEAKHDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMR 241
           R H   E            +        D   L   +       D  D  C  +   L  
Sbjct: 421 RKHCQIESQEETGMPNKASKQDPPTDQGDKPALSLPL----ASFDASDLECA-LCMRLFY 475

Query: 242 EPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQ----EQLIPNLAMKEVIDAFISE 296
           EP  TP G T+  K +E  L       P+ +  L+Q     +   N+ M+E+I  F+ E
Sbjct: 476 EPVTTPCGHTFCLKCLERCLDHNAKC-PLCKDGLSQCLASRKYSKNVIMEELIAKFLPE 533


>gi|225735595 RNA polymerase II associated protein 3 isoform 3 [Homo
           sapiens]
          Length = 506

 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 32/84 (38%), Positives = 46/84 (54%)

Query: 30  KEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALEL 89
           K++GN  F   KY  A  CY R I  +   A+   NRA+ YLK+Q++E+A  DC +A+ L
Sbjct: 127 KDRGNGFFKEGKYERAIECYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILL 186

Query: 90  DGQSVKAHFFLGQCQLEMESYDEA 113
           DG   KA    G  +  +   +EA
Sbjct: 187 DGSYSKAFARRGTARTFLGKLNEA 210



 Score = 35.0 bits (79), Expect = 0.082
 Identities = 19/68 (27%), Positives = 34/68 (50%)

Query: 56  NPLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIA 115
           +P   V  TNRA  Y ++++   A +DC  A+ L+    KA+   G  +  ++  +EA  
Sbjct: 4   DPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKK 63

Query: 116 NLQRAYSL 123
           + +R   L
Sbjct: 64  DYERVLEL 71


>gi|221219056 DnaJ (Hsp40) homolog, subfamily C, member 7 isoform 2
           [Homo sapiens]
          Length = 438

 Score = 58.5 bits (140), Expect = 7e-09
 Identities = 47/200 (23%), Positives = 88/200 (44%), Gaps = 20/200 (10%)

Query: 30  KEQGNRLFVGRKYPEAAACYGRAITRNP----LVAVYYTNRALCYLKMQQHEQALADCRR 85
           KE GN+ F    Y  A   Y  A+  +P      A  Y NR     K+++ + A+ DC  
Sbjct: 204 KEDGNKAFKEGNYKLAYELYTEALGIDPNNIKTNAKLYCNRGTVNSKLRKLDDAIEDCTN 263

Query: 86  ALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAK-EQRLNFGDDIPSALRIAKK 144
           A++LD   +KA+    QC ++ E Y+EA+ + ++ Y   K ++      +    L+ +K+
Sbjct: 264 AVKLDDTYIKAYLRRAQCYMDTEQYEEAVRDYEKVYQTEKTKEHKQLLKNAQLELKKSKR 323

Query: 145 KRWNSIEERRIHQESELHSYLSRLIAAERERELEECQRNHEGDEDDSHVRAQQACIEAKH 204
           K +  I         + ++    +  A R+R L      H G           A ++ + 
Sbjct: 324 KDYYKI------LGVDKNASEDEIKKAYRKRALMHHPDRHSG---------ASAEVQKEE 368

Query: 205 DKYMADMDELFSQVDEKRKK 224
           +K   ++ E F+ + + +KK
Sbjct: 369 EKKFKEVGEAFTILSDPKKK 388



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 22/67 (32%), Positives = 35/67 (52%)

Query: 57  PLVAVYYTNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIAN 116
           P  A YY NRA   + + +  +AL D ++++ LD   V+ H   G+C L + +   A  +
Sbjct: 3   PKNASYYGNRAATLMMLGRFREALGDAQQSVRLDDSFVRGHLREGKCHLSLGNAMAACRS 62

Query: 117 LQRAYSL 123
            QRA  L
Sbjct: 63  FQRALEL 69


>gi|75750484 cardiomyopathy associated 4 isoform 2 [Homo sapiens]
          Length = 929

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 3/101 (2%)

Query: 26  AQELKEQGNRLFVGRKYPEAAACYGRAITRNP---LVAVYYTNRALCYLKMQQHEQALAD 82
           A +LKE+GNR F  + Y  A   Y +A+       L+A  Y NRA C LK + + QA +D
Sbjct: 6   AVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASD 65

Query: 83  CRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
             RA++++   +KA +   Q    +   D+A  ++QR  +L
Sbjct: 66  ASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATL 106


>gi|27477061 cardiomyopathy associated 4 isoform 1 [Homo sapiens]
          Length = 931

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 34/101 (33%), Positives = 54/101 (53%), Gaps = 3/101 (2%)

Query: 26  AQELKEQGNRLFVGRKYPEAAACYGRAITRNP---LVAVYYTNRALCYLKMQQHEQALAD 82
           A +LKE+GNR F  + Y  A   Y +A+       L+A  Y NRA C LK + + QA +D
Sbjct: 6   AVQLKEEGNRHFQLQDYKAATNSYSQALKLTKDKALLATLYRNRAACGLKTESYVQAASD 65

Query: 83  CRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
             RA++++   +KA +   Q    +   D+A  ++QR  +L
Sbjct: 66  ASRAIDINSSDIKALYRRCQALEHLGKLDQAFKDVQRCATL 106


>gi|75677570 dyslexia susceptibility 1 candidate 1 isoform a [Homo
           sapiens]
          Length = 420

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 36/117 (30%), Positives = 58/117 (49%), Gaps = 10/117 (8%)

Query: 21  EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQAL 80
           EK+P  + LK++GN+LF    Y  A   Y  AI  N  + + Y NRA C+LK++   +A+
Sbjct: 287 EKNP--EWLKDKGNKLFATENYLAAINAYNLAIRLNNKMPLLYLNRAACHLKLKNLHKAI 344

Query: 81  ADCRRALEL--------DGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRL 129
            D  +ALEL            +KAH   G    ++E Y E + + + A  +    ++
Sbjct: 345 EDSSKALELLMPPVTDNANARMKAHVRRGTAFCQLELYVEGLQDYEAALKIDPSNKI 401


>gi|19923193 heat shock 70kD protein binding protein [Homo sapiens]
          Length = 369

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 44/176 (25%), Positives = 82/176 (46%), Gaps = 19/176 (10%)

Query: 21  EKSPSAQELKEQGNRLFVGR-------KYPEAAACYGRAITRNPLVAVYYTNRALCYLKM 73
           E +   +E+ +Q N   V         +  +A   +  AI  NP +A+ Y  RA  ++K+
Sbjct: 102 ENAEITEEMMDQANDKKVAAIEALNDGELQKAIDLFTDAIKLNPRLAILYAKRASVFVKL 161

Query: 74  QQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGD 133
           Q+   A+ DC RA+E++  S + + + G+    +  ++EA      A+ LA   +L++ +
Sbjct: 162 QKPNAAIRDCDRAIEINPDSAQPYKWRGKAHRLLGHWEEA------AHDLALACKLDYDE 215

Query: 134 DIPSALRIAKKKRWNSIEERRIH----QESELHSYLSRLIAAERERELEECQRNHE 185
           D  + L+  + +     E RR +    +E E+   + R+  A  E   E  QR  E
Sbjct: 216 DASAMLKEVQPRAQKIAEHRRKYERKREEREIKERIERVKKAREEH--ERAQREEE 269


>gi|224809329 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/154 (24%), Positives = 73/154 (47%), Gaps = 25/154 (16%)

Query: 21  EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAIT---------------RNPLVAVYYTN 65
           EK   A  +KE+G   F G KY +A   YG+ ++                   +   + N
Sbjct: 263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLN 322

Query: 66  RALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAK 125
            A+CYLK++++ +A+  C +AL LD  + K  +  G+ QL M  ++ A  + ++   +  
Sbjct: 323 LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382

Query: 126 EQRLNFGDDIPSALRIA---KKKRWNSIEERRIH 156
           + +        + L+I+   KK + ++  +RRI+
Sbjct: 383 QNK-------AARLQISMCQKKAKEHNERDRRIY 409


>gi|224809327 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/154 (24%), Positives = 73/154 (47%), Gaps = 25/154 (16%)

Query: 21  EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAIT---------------RNPLVAVYYTN 65
           EK   A  +KE+G   F G KY +A   YG+ ++                   +   + N
Sbjct: 263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLN 322

Query: 66  RALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAK 125
            A+CYLK++++ +A+  C +AL LD  + K  +  G+ QL M  ++ A  + ++   +  
Sbjct: 323 LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382

Query: 126 EQRLNFGDDIPSALRIA---KKKRWNSIEERRIH 156
           + +        + L+I+   KK + ++  +RRI+
Sbjct: 383 QNK-------AARLQISMCQKKAKEHNERDRRIY 409


>gi|4758384 FK506 binding protein 5 isoform 1 [Homo sapiens]
          Length = 457

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/154 (24%), Positives = 73/154 (47%), Gaps = 25/154 (16%)

Query: 21  EKSPSAQELKEQGNRLFVGRKYPEAAACYGRAIT---------------RNPLVAVYYTN 65
           EK   A  +KE+G   F G KY +A   YG+ ++                   +   + N
Sbjct: 263 EKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKESKASESFLLAAFLN 322

Query: 66  RALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAK 125
            A+CYLK++++ +A+  C +AL LD  + K  +  G+ QL M  ++ A  + ++   +  
Sbjct: 323 LAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNP 382

Query: 126 EQRLNFGDDIPSALRIA---KKKRWNSIEERRIH 156
           + +        + L+I+   KK + ++  +RRI+
Sbjct: 383 QNK-------AARLQISMCQKKAKEHNERDRRIY 409


>gi|4503729 FK506 binding protein 52 [Homo sapiens]
          Length = 459

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 47/206 (22%), Positives = 87/206 (42%), Gaps = 31/206 (15%)

Query: 19  SPEKSPSAQELKEQGNRLFVGRKYPEAAACYGRAIT---------------RNPLVAVYY 63
           S EK   +  +KE+G   F   KY +A   Y + ++                  L    +
Sbjct: 263 SEEKLEQSTIVKERGTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASH 322

Query: 64  TNRALCYLKMQQHEQALADCRRALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSL 123
            N A+C+LK+Q    A+  C +ALELD  + K  F  G+  L +  ++ A A+ Q+   L
Sbjct: 323 LNLAMCHLKLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQL 382

Query: 124 AKEQRLNFGDDIPSALRIAKKKRWNSIEERRIHQESELHSYL-SRLIAAERERELEECQR 182
               +        + L + +++       R++ +E +L++ +  RL   E + + E    
Sbjct: 383 YPNNKA-----AKTQLAVCQQR-----IRRQLAREKKLYANMFERLAEEENKAKAEASSG 432

Query: 183 NHEGD-----EDDSHVRAQQACIEAK 203
           +H  D     E  S+    Q+ +E +
Sbjct: 433 DHPTDTEMKEEQKSNTAGSQSQVETE 458


>gi|37622896 LON peptidase N-terminal domain and ring finger 3
           isoform 2 [Homo sapiens]
          Length = 718

 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 67/277 (24%), Positives = 104/277 (37%), Gaps = 33/277 (11%)

Query: 26  AQELKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRR 85
           A +L+ +GNRL+  R+   A   Y  A+   P   + Y+NR+  Y  ++ HE AL D   
Sbjct: 243 ASQLRHEGNRLYRERQVEAALLKYNEAVKLAPNDHLLYSNRSQIYFTLESHENALHDAEI 302

Query: 86  ALELDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKKK 145
           A +L     K +  L  C     S +EA A                GD   S+L    K 
Sbjct: 303 ACKLRPMGFKDNLELPHC----SSQEEAAAR---------------GDG--SSLMDPAKV 341

Query: 146 RWNSIEERRIHQESELHSY--LSRLIAAERERELEECQRNHEGDEDDSHVRAQQACIEAK 203
           + +  +     QE E   +   S   A+ +  + +E +R H   E            +  
Sbjct: 342 KGDGQQHHMKDQEEEEEKWDATSPKAASSKTGKCQEKKRKHCQIESQEETGMPNKASKQD 401

Query: 204 HDKYMADMDELFSQVDEKRKKRDIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQR 263
                 D   L   +       D  D  C  +   L  EP  TP G T+  K +E  L  
Sbjct: 402 PPTDQGDKPALSLPL----ASFDASDLECA-LCMRLFYEPVTTPCGHTFCLKCLERCLDH 456

Query: 264 VGHFDPVTRSPLTQ----EQLIPNLAMKEVIDAFISE 296
                P+ +  L+Q     +   N+ M+E+I  F+ E
Sbjct: 457 NAKC-PLCKDGLSQCLASRKYSKNVIMEELIAKFLPE 492


>gi|49640011 tetratricopeptide repeat domain 3 [Homo sapiens]
          Length = 2025

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 35/116 (30%), Positives = 51/116 (43%)

Query: 29  LKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALE 88
           +K +GN  F   ++  A   Y RAI   P   + Y NRALC+L+  Q   AL D +RA  
Sbjct: 234 MKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATI 293

Query: 89  LDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKK 144
           L     K H+        +  YD A+    +A  L K       D I   +++ K+
Sbjct: 294 LKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQ 349


>gi|49640009 tetratricopeptide repeat domain 3 [Homo sapiens]
          Length = 2025

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 35/116 (30%), Positives = 51/116 (43%)

Query: 29  LKEQGNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQHEQALADCRRALE 88
           +K +GN  F   ++  A   Y RAI   P   + Y NRALC+L+  Q   AL D +RA  
Sbjct: 234 MKMKGNEEFSKERFDIAIIYYTRAIEYRPENYLLYGNRALCFLRTGQFRNALGDGKRATI 293

Query: 89  LDGQSVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKEQRLNFGDDIPSALRIAKK 144
           L     K H+        +  YD A+    +A  L K       D I   +++ K+
Sbjct: 294 LKNTWPKGHYRYCDALSMLGEYDWALQANIKAQKLCKNDPEGIKDLIQQHVKLQKQ 349


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,138,928
Number of Sequences: 37866
Number of extensions: 569936
Number of successful extensions: 2756
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 2437
Number of HSP's gapped (non-prelim): 401
length of query: 303
length of database: 18,247,518
effective HSP length: 102
effective length of query: 201
effective length of database: 14,385,186
effective search space: 2891422386
effective search space used: 2891422386
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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