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Search of human proteins with 56119108
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56119108 schlafen family member 13 [Homo sapiens]
(897 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56119108 schlafen family member 13 [Homo sapiens] 1808 0.0
gi|157388965 schlafen family member 11 [Homo sapiens] 1350 0.0
gi|157388963 schlafen family member 11 [Homo sapiens] 1350 0.0
gi|157388961 schlafen family member 11 [Homo sapiens] 1350 0.0
gi|157388959 schlafen family member 11 [Homo sapiens] 1350 0.0
gi|157388957 schlafen family member 11 [Homo sapiens] 1350 0.0
gi|145580600 schlafen family member 5 [Homo sapiens] 852 0.0
gi|193788705 schlafen family member 14 [Homo sapiens] 697 0.0
gi|157388955 schlafen family member 12 [Homo sapiens] 377 e-104
gi|222537745 schlafen family member 12-like [Homo sapiens] 371 e-102
gi|45267821 schlafen-like 1 [Homo sapiens] 38 0.037
gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens] 35 0.24
gi|223890153 DSN1, MIND kinetochore complex component, homolog i... 33 0.91
gi|223890149 DSN1, MIND kinetochore complex component, homolog i... 33 0.91
gi|223890147 DSN1, MIND kinetochore complex component, homolog i... 33 0.91
gi|223972618 DSN1, MIND kinetochore complex component, homolog i... 33 0.91
gi|32307166 Rho guanine exchange factor 15 [Homo sapiens] 33 0.91
gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [H... 32 2.0
gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens] 32 2.0
gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens] 32 2.0
gi|194018490 ATPase family, AAA domain containing 3C [Homo sapiens] 32 2.6
gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens] 31 5.9
>gi|56119108 schlafen family member 13 [Homo sapiens]
Length = 897
Score = 1808 bits (4682), Expect = 0.0
Identities = 897/897 (100%), Positives = 897/897 (100%)
Query: 1 MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV 60
MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV
Sbjct: 1 MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV 60
Query: 61 IQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKD 120
IQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKD
Sbjct: 61 IQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKD 120
Query: 121 GSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVY 180
GSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVY
Sbjct: 121 GSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVY 180
Query: 181 QNISESNPAYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANT 240
QNISESNPAYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANT
Sbjct: 181 QNISESNPAYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANT 240
Query: 241 EGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVE 300
EGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVE
Sbjct: 241 EGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVE 300
Query: 301 VFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPD 360
VFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPD
Sbjct: 301 VFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPD 360
Query: 361 FAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQH 420
FAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQH
Sbjct: 361 FAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQH 420
Query: 421 EGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD 480
EGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD
Sbjct: 421 EGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD 480
Query: 481 AEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYS 540
AEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYS
Sbjct: 481 AEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYS 540
Query: 541 LAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGL 600
LAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGL
Sbjct: 541 LAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGL 600
Query: 601 PGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRETFLREKFE 660
PGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRETFLREKFE
Sbjct: 601 PGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRETFLREKFE 660
Query: 661 HIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHSGLPPLSA 720
HIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHSGLPPLSA
Sbjct: 661 HIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHSGLPPLSA 720
Query: 721 QYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGVPGNTKII 780
QYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGVPGNTKII
Sbjct: 721 QYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGVPGNTKII 780
Query: 781 KNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKKMVVQLSD 840
KNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKKMVVQLSD
Sbjct: 781 KNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKKMVVQLSD 840
Query: 841 ACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHLYIFL 897
ACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHLYIFL
Sbjct: 841 ACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHLYIFL 897
>gi|157388965 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 1350 bits (3493), Expect = 0.0
Identities = 693/903 (76%), Positives = 757/903 (83%), Gaps = 14/903 (1%)
Query: 1 MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV 60
MEAN C L V PSYPDLVI+VGEVTLGEENRKKLQK QRDQE+ RV+RAACALLNSGGGV
Sbjct: 1 MEANQCPLVVEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGV 60
Query: 61 IQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKD 120
I+M A + E P EMGLDLE+SLR+LIQ LQAFFETKQ GRCFYIFVKSWS PF +D
Sbjct: 61 IRM--AKKVEHPVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPED 118
Query: 121 GSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVY 180
S R+CSLSSSLY RS TSV M+SR+AF FLKTK K ++ EG P KI K VY
Sbjct: 119 RSVKPRLCSLSSSLYRRSETSVRSMDSREAFCFLKTKR---KPKILEEG-PFHKIHKGVY 174
Query: 181 QNISESNPAYE-------VFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEY 233
Q + S+PA +FQ D +EYGEIL FPES +EFKQFSTKH Q+YV+ IPEY
Sbjct: 175 QELPNSDPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEY 234
Query: 234 ISAFANTEGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVE 293
+ AFANT GGYLFIGVDDKSR+VLGCAKE VDPDSL+ I +AI KLP VHFC + +
Sbjct: 235 VPAFANTGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPIT 294
Query: 294 YSTKIVEVFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDA 353
++ KIV V ELYGY C+I+V FCC VFSEAP SW+V +KY+ LTTE+WV M D
Sbjct: 295 FTLKIVNVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDT 354
Query: 354 DPEFPPDFAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLW 413
DP+ +E FE QLSLS P L RPVYSKKGLEHK +LQQ LF VPPG+L TPESLW
Sbjct: 355 DPDLL-QLSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLW 413
Query: 414 KELSLQHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
++L +H GL+ELI+KQM+PF +GI+I SRSWAVDLNLQEKPGVICDALLIAQNSTPILY
Sbjct: 414 RDLISEHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
Query: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM
Sbjct: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
Query: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR
Sbjct: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
Query: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRET 653
ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETR+T
Sbjct: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKT 653
Query: 654 FLREKFEHIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHS 713
FLRE FEHIQHIVIDEAQNFRTEDGDWY KAK+IT+R K PG+LWIFLDYFQTSHL S
Sbjct: 654 FLRENFEHIQHIVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCS 713
Query: 714 GLPPLSAQYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGV 773
GLPPLS QYPREELTR+VRNAD IA+Y+Q+EMQ+I NP NIP G L + EA+W GV
Sbjct: 714 GLPPLSDQYPREELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGV 773
Query: 774 PGNTKIIKNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKK 833
G +I K T+EQI+T VADTCR FF+RGYSPKDVAVLVST EVE Y+ +LLKAMRKK
Sbjct: 774 QGTLRIKKYLTVEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKK 833
Query: 834 MVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHL 893
VVQLSDACDMLG HIVLDSVRRFSGLERSIVFGIHPRTADPAILPN+LICLASRAKQHL
Sbjct: 834 RVVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHL 893
Query: 894 YIF 896
YIF
Sbjct: 894 YIF 896
>gi|157388963 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 1350 bits (3493), Expect = 0.0
Identities = 693/903 (76%), Positives = 757/903 (83%), Gaps = 14/903 (1%)
Query: 1 MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV 60
MEAN C L V PSYPDLVI+VGEVTLGEENRKKLQK QRDQE+ RV+RAACALLNSGGGV
Sbjct: 1 MEANQCPLVVEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGV 60
Query: 61 IQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKD 120
I+M A + E P EMGLDLE+SLR+LIQ LQAFFETKQ GRCFYIFVKSWS PF +D
Sbjct: 61 IRM--AKKVEHPVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPED 118
Query: 121 GSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVY 180
S R+CSLSSSLY RS TSV M+SR+AF FLKTK K ++ EG P KI K VY
Sbjct: 119 RSVKPRLCSLSSSLYRRSETSVRSMDSREAFCFLKTKR---KPKILEEG-PFHKIHKGVY 174
Query: 181 QNISESNPAYE-------VFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEY 233
Q + S+PA +FQ D +EYGEIL FPES +EFKQFSTKH Q+YV+ IPEY
Sbjct: 175 QELPNSDPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEY 234
Query: 234 ISAFANTEGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVE 293
+ AFANT GGYLFIGVDDKSR+VLGCAKE VDPDSL+ I +AI KLP VHFC + +
Sbjct: 235 VPAFANTGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPIT 294
Query: 294 YSTKIVEVFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDA 353
++ KIV V ELYGY C+I+V FCC VFSEAP SW+V +KY+ LTTE+WV M D
Sbjct: 295 FTLKIVNVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDT 354
Query: 354 DPEFPPDFAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLW 413
DP+ +E FE QLSLS P L RPVYSKKGLEHK +LQQ LF VPPG+L TPESLW
Sbjct: 355 DPDLL-QLSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLW 413
Query: 414 KELSLQHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
++L +H GL+ELI+KQM+PF +GI+I SRSWAVDLNLQEKPGVICDALLIAQNSTPILY
Sbjct: 414 RDLISEHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
Query: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM
Sbjct: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
Query: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR
Sbjct: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
Query: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRET 653
ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETR+T
Sbjct: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKT 653
Query: 654 FLREKFEHIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHS 713
FLRE FEHIQHIVIDEAQNFRTEDGDWY KAK+IT+R K PG+LWIFLDYFQTSHL S
Sbjct: 654 FLRENFEHIQHIVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCS 713
Query: 714 GLPPLSAQYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGV 773
GLPPLS QYPREELTR+VRNAD IA+Y+Q+EMQ+I NP NIP G L + EA+W GV
Sbjct: 714 GLPPLSDQYPREELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGV 773
Query: 774 PGNTKIIKNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKK 833
G +I K T+EQI+T VADTCR FF+RGYSPKDVAVLVST EVE Y+ +LLKAMRKK
Sbjct: 774 QGTLRIKKYLTVEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKK 833
Query: 834 MVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHL 893
VVQLSDACDMLG HIVLDSVRRFSGLERSIVFGIHPRTADPAILPN+LICLASRAKQHL
Sbjct: 834 RVVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHL 893
Query: 894 YIF 896
YIF
Sbjct: 894 YIF 896
>gi|157388961 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 1350 bits (3493), Expect = 0.0
Identities = 693/903 (76%), Positives = 757/903 (83%), Gaps = 14/903 (1%)
Query: 1 MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV 60
MEAN C L V PSYPDLVI+VGEVTLGEENRKKLQK QRDQE+ RV+RAACALLNSGGGV
Sbjct: 1 MEANQCPLVVEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGV 60
Query: 61 IQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKD 120
I+M A + E P EMGLDLE+SLR+LIQ LQAFFETKQ GRCFYIFVKSWS PF +D
Sbjct: 61 IRM--AKKVEHPVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPED 118
Query: 121 GSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVY 180
S R+CSLSSSLY RS TSV M+SR+AF FLKTK K ++ EG P KI K VY
Sbjct: 119 RSVKPRLCSLSSSLYRRSETSVRSMDSREAFCFLKTKR---KPKILEEG-PFHKIHKGVY 174
Query: 181 QNISESNPAYE-------VFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEY 233
Q + S+PA +FQ D +EYGEIL FPES +EFKQFSTKH Q+YV+ IPEY
Sbjct: 175 QELPNSDPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEY 234
Query: 234 ISAFANTEGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVE 293
+ AFANT GGYLFIGVDDKSR+VLGCAKE VDPDSL+ I +AI KLP VHFC + +
Sbjct: 235 VPAFANTGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPIT 294
Query: 294 YSTKIVEVFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDA 353
++ KIV V ELYGY C+I+V FCC VFSEAP SW+V +KY+ LTTE+WV M D
Sbjct: 295 FTLKIVNVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDT 354
Query: 354 DPEFPPDFAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLW 413
DP+ +E FE QLSLS P L RPVYSKKGLEHK +LQQ LF VPPG+L TPESLW
Sbjct: 355 DPDLL-QLSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLW 413
Query: 414 KELSLQHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
++L +H GL+ELI+KQM+PF +GI+I SRSWAVDLNLQEKPGVICDALLIAQNSTPILY
Sbjct: 414 RDLISEHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
Query: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM
Sbjct: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
Query: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR
Sbjct: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
Query: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRET 653
ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETR+T
Sbjct: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKT 653
Query: 654 FLREKFEHIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHS 713
FLRE FEHIQHIVIDEAQNFRTEDGDWY KAK+IT+R K PG+LWIFLDYFQTSHL S
Sbjct: 654 FLRENFEHIQHIVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCS 713
Query: 714 GLPPLSAQYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGV 773
GLPPLS QYPREELTR+VRNAD IA+Y+Q+EMQ+I NP NIP G L + EA+W GV
Sbjct: 714 GLPPLSDQYPREELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGV 773
Query: 774 PGNTKIIKNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKK 833
G +I K T+EQI+T VADTCR FF+RGYSPKDVAVLVST EVE Y+ +LLKAMRKK
Sbjct: 774 QGTLRIKKYLTVEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKK 833
Query: 834 MVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHL 893
VVQLSDACDMLG HIVLDSVRRFSGLERSIVFGIHPRTADPAILPN+LICLASRAKQHL
Sbjct: 834 RVVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHL 893
Query: 894 YIF 896
YIF
Sbjct: 894 YIF 896
>gi|157388959 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 1350 bits (3493), Expect = 0.0
Identities = 693/903 (76%), Positives = 757/903 (83%), Gaps = 14/903 (1%)
Query: 1 MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV 60
MEAN C L V PSYPDLVI+VGEVTLGEENRKKLQK QRDQE+ RV+RAACALLNSGGGV
Sbjct: 1 MEANQCPLVVEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGV 60
Query: 61 IQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKD 120
I+M A + E P EMGLDLE+SLR+LIQ LQAFFETKQ GRCFYIFVKSWS PF +D
Sbjct: 61 IRM--AKKVEHPVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPED 118
Query: 121 GSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVY 180
S R+CSLSSSLY RS TSV M+SR+AF FLKTK K ++ EG P KI K VY
Sbjct: 119 RSVKPRLCSLSSSLYRRSETSVRSMDSREAFCFLKTKR---KPKILEEG-PFHKIHKGVY 174
Query: 181 QNISESNPAYE-------VFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEY 233
Q + S+PA +FQ D +EYGEIL FPES +EFKQFSTKH Q+YV+ IPEY
Sbjct: 175 QELPNSDPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEY 234
Query: 234 ISAFANTEGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVE 293
+ AFANT GGYLFIGVDDKSR+VLGCAKE VDPDSL+ I +AI KLP VHFC + +
Sbjct: 235 VPAFANTGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPIT 294
Query: 294 YSTKIVEVFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDA 353
++ KIV V ELYGY C+I+V FCC VFSEAP SW+V +KY+ LTTE+WV M D
Sbjct: 295 FTLKIVNVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDT 354
Query: 354 DPEFPPDFAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLW 413
DP+ +E FE QLSLS P L RPVYSKKGLEHK +LQQ LF VPPG+L TPESLW
Sbjct: 355 DPDLL-QLSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLW 413
Query: 414 KELSLQHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
++L +H GL+ELI+KQM+PF +GI+I SRSWAVDLNLQEKPGVICDALLIAQNSTPILY
Sbjct: 414 RDLISEHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
Query: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM
Sbjct: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
Query: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR
Sbjct: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
Query: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRET 653
ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETR+T
Sbjct: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKT 653
Query: 654 FLREKFEHIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHS 713
FLRE FEHIQHIVIDEAQNFRTEDGDWY KAK+IT+R K PG+LWIFLDYFQTSHL S
Sbjct: 654 FLRENFEHIQHIVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCS 713
Query: 714 GLPPLSAQYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGV 773
GLPPLS QYPREELTR+VRNAD IA+Y+Q+EMQ+I NP NIP G L + EA+W GV
Sbjct: 714 GLPPLSDQYPREELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGV 773
Query: 774 PGNTKIIKNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKK 833
G +I K T+EQI+T VADTCR FF+RGYSPKDVAVLVST EVE Y+ +LLKAMRKK
Sbjct: 774 QGTLRIKKYLTVEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKK 833
Query: 834 MVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHL 893
VVQLSDACDMLG HIVLDSVRRFSGLERSIVFGIHPRTADPAILPN+LICLASRAKQHL
Sbjct: 834 RVVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHL 893
Query: 894 YIF 896
YIF
Sbjct: 894 YIF 896
>gi|157388957 schlafen family member 11 [Homo sapiens]
Length = 901
Score = 1350 bits (3493), Expect = 0.0
Identities = 693/903 (76%), Positives = 757/903 (83%), Gaps = 14/903 (1%)
Query: 1 MEANHCSLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGV 60
MEAN C L V PSYPDLVI+VGEVTLGEENRKKLQK QRDQE+ RV+RAACALLNSGGGV
Sbjct: 1 MEANQCPLVVEPSYPDLVINVGEVTLGEENRKKLQKIQRDQEKERVMRAACALLNSGGGV 60
Query: 61 IQMEMANRDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKD 120
I+M A + E P EMGLDLE+SLR+LIQ LQAFFETKQ GRCFYIFVKSWS PF +D
Sbjct: 61 IRM--AKKVEHPVEMGLDLEQSLRELIQSSDLQAFFETKQQGRCFYIFVKSWSSGPFPED 118
Query: 121 GSFNSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVY 180
S R+CSLSSSLY RS TSV M+SR+AF FLKTK K ++ EG P KI K VY
Sbjct: 119 RSVKPRLCSLSSSLYRRSETSVRSMDSREAFCFLKTKR---KPKILEEG-PFHKIHKGVY 174
Query: 181 QNISESNPAYE-------VFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEY 233
Q + S+PA +FQ D +EYGEIL FPES +EFKQFSTKH Q+YV+ IPEY
Sbjct: 175 QELPNSDPADPNSDPADLIFQKDYLEYGEILPFPESQLVEFKQFSTKHFQEYVKRTIPEY 234
Query: 234 ISAFANTEGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVE 293
+ AFANT GGYLFIGVDDKSR+VLGCAKE VDPDSL+ I +AI KLP VHFC + +
Sbjct: 235 VPAFANTGGGYLFIGVDDKSREVLGCAKENVDPDSLRRKIEQAIYKLPCVHFCQPQRPIT 294
Query: 294 YSTKIVEVFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDA 353
++ KIV V ELYGY C+I+V FCC VFSEAP SW+V +KY+ LTTE+WV M D
Sbjct: 295 FTLKIVNVLKRGELYGYACMIRVNPFCCAVFSEAPNSWIVEDKYVCSLTTEKWVGMMTDT 354
Query: 354 DPEFPPDFAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLW 413
DP+ +E FE QLSLS P L RPVYSKKGLEHK +LQQ LF VPPG+L TPESLW
Sbjct: 355 DPDLL-QLSEDFECQLSLSSGPPLSRPVYSKKGLEHKKELQQLLFSVPPGYLRYTPESLW 413
Query: 414 KELSLQHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
++L +H GL+ELI+KQM+PF +GI+I SRSWAVDLNLQEKPGVICDALLIAQNSTPILY
Sbjct: 414 RDLISEHRGLEELINKQMQPFFRGILIFSRSWAVDLNLQEKPGVICDALLIAQNSTPILY 473
Query: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM
Sbjct: 474 TILREQDAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPM 533
Query: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR
Sbjct: 534 DYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNR 593
Query: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRET 653
ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETR+T
Sbjct: 594 ELFVHGLPGSGKTIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRKT 653
Query: 654 FLREKFEHIQHIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHS 713
FLRE FEHIQHIVIDEAQNFRTEDGDWY KAK+IT+R K PG+LWIFLDYFQTSHL S
Sbjct: 654 FLRENFEHIQHIVIDEAQNFRTEDGDWYGKAKSITRRAKGGPGILWIFLDYFQTSHLDCS 713
Query: 714 GLPPLSAQYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGV 773
GLPPLS QYPREELTR+VRNAD IA+Y+Q+EMQ+I NP NIP G L + EA+W GV
Sbjct: 714 GLPPLSDQYPREELTRIVRNADPIAKYLQKEMQVIRSNPSFNIPTGCLEVFPEAEWSQGV 773
Query: 774 PGNTKIIKNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKK 833
G +I K T+EQI+T VADTCR FF+RGYSPKDVAVLVST EVE Y+ +LLKAMRKK
Sbjct: 774 QGTLRIKKYLTVEQIMTCVADTCRRFFDRGYSPKDVAVLVSTAKEVEHYKYELLKAMRKK 833
Query: 834 MVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHL 893
VVQLSDACDMLG HIVLDSVRRFSGLERSIVFGIHPRTADPAILPN+LICLASRAKQHL
Sbjct: 834 RVVQLSDACDMLGDHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNVLICLASRAKQHL 893
Query: 894 YIF 896
YIF
Sbjct: 894 YIF 896
>gi|145580600 schlafen family member 5 [Homo sapiens]
Length = 891
Score = 852 bits (2200), Expect = 0.0
Identities = 455/902 (50%), Positives = 609/902 (67%), Gaps = 34/902 (3%)
Query: 8 LGVYPSYPDLVIDVGEVTLGEENRKKLQKTQRDQERARVIRAACALLNSGGGVIQMEMAN 67
+ V ++P+ V+D G+VTLG + R+++ R+++ ++RA CALLNSGGG+I+ E+ N
Sbjct: 5 IDVDTNFPECVVDAGKVTLGTQQRQEMDPRLREKQNEIILRAVCALLNSGGGIIKAEIEN 64
Query: 68 RDERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKDGSFNSRI 127
+ G+ L+ P ++ + Q F IFVKSW+ + + +
Sbjct: 65 KGYNYERHGVGLDVP-------PIFRSHLDKMQKENHFLIFVKSWNTEAGVP-------L 110
Query: 128 CSLSSSLYCRSGTSVLHMNSRQAFDFLKTK-ERQSKYNLINEGSPPSKIMKAVYQ-NISE 185
+L S+LY R TS M+S++A FLK + + + N+ N P + Y+ NI+
Sbjct: 111 ATLCSNLYHRERTSTDVMDSQEALAFLKCRTQTPTNINVSNSLGPQAAQGSVQYEGNINV 170
Query: 186 SNPAYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANTEGGYL 245
S A +F ++Y E L+ PES +EF FST + V++ +P+ +SAFANTEGGY+
Sbjct: 171 SAAA--LFDRKRLQYLEKLNLPESTHVEFVMFSTD-VSHCVKDRLPKCVSAFANTEGGYV 227
Query: 246 FIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVEVFCGK 305
F GV D++ +V+GC KE++D SL+ I I KLP+ HFC+ +P ++Y +EV
Sbjct: 228 FFGVHDETCQVIGCEKEKIDLTSLRASIDGCIKKLPVHHFCTQRPEIKYVLNFLEVHDKG 287
Query: 306 ELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPDFAEAF 365
L GY+C IKV+ FCC VF++ P SW V++ +R L T EW MM+ADP+
Sbjct: 288 ALRGYVCAIKVEKFCCAVFAKVPSSWQVKDNRVRQLPTREWTAWMMEADPDLSR--CPEM 345
Query: 366 ESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQHEGLKE 425
QLSLS + +PV K E + Q+ FPV + TPESL+KEL QH+GL++
Sbjct: 346 VLQLSLSSATPRSKPVCIHKNSECLKEQQKRYFPVFSDRVVYTPESLYKELFSQHKGLRD 405
Query: 426 LIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEGQD 485
LI+ +MRPFSQGI+I S+SWAVDL LQEK GVICDALLI+QN+TPILYTI + DA +
Sbjct: 406 LINTEMRPFSQGILIFSQSWAVDLGLQEKQGVICDALLISQNNTPILYTIFSKWDAGCKG 465
Query: 486 YCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQ 545
Y A++LKQKLVN GGYTG++C+ V L+ + A+++ ++ + YP SY+ Q
Sbjct: 466 YSMIVAYSLKQKLVNKGGYTGRLCITPLVCVLNSDRKAQSVYSSYLQI-YPESYNFMTPQ 524
Query: 546 HMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGK 605
HMEALLQSLVIVLLGF+S LS++LG EVLNLLT +QYE+ S++LRK RELFVHGLPGSGK
Sbjct: 525 HMEALLQSLVIVLLGFKSFLSEELGSEVLNLLTNKQYELLSKNLRKTRELFVHGLPGSGK 584
Query: 606 TIMAMKIMEKIRNVFHCEAHRILYVCENQPLRNFIS--DRNICRAETRETFLREKFEHIQ 663
TI+A++IMEKIRNVFHCE ILY+CENQPL+ +S +NIC+ TR+TF++ FEHIQ
Sbjct: 585 TILALRIMEKIRNVFHCEPANILYICENQPLKKLVSFSKKNICQPVTRKTFMKNNFEHIQ 644
Query: 664 HIVIDEAQNFRTEDGDWYRKAKTITQREKDCPGVLWIFLDYFQTSHLGHSGLPPLSAQYP 723
HI+ID+AQNFRTEDGDWY KAK ITQ +D PGVLWIFLDYFQT HL SGLPP S QYP
Sbjct: 645 HIIIDDAQNFRTEDGDWYGKAKFITQTARDGPGVLWIFLDYFQTYHLSCSGLPPPSDQYP 704
Query: 724 REELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILSEAKWVPGVPGNTKIIKNF 783
REE+ RVVRNA IA Y+QQ MQ +NPP N+P G L +L E KW GVPGN +II++
Sbjct: 705 REEINRVVRNAGPIANYLQQVMQEARQNPPPNLPPGSLVMLYEPKWAQGVPGNLEIIEDL 764
Query: 784 TLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAMRKK---------- 833
LE+I+ YVA+ CR GYSPKD+AVL + +EVE+Y+ +LL AMRK+
Sbjct: 765 NLEEILIYVANKCRFLLRNGYSPKDIAVLFTKASEVEKYKDRLLTAMRKRKLSQLHEESD 824
Query: 834 MVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAKQHL 893
+++Q+ DA D+L HIVLDSV RFSGLER+IVFGI+P A PA N+L+CLASRAK+HL
Sbjct: 825 LLLQIGDASDVLTDHIVLDSVCRFSGLERNIVFGINPGVAPPAGAYNLLLCLASRAKRHL 884
Query: 894 YI 895
YI
Sbjct: 885 YI 886
>gi|193788705 schlafen family member 14 [Homo sapiens]
Length = 912
Score = 697 bits (1798), Expect = 0.0
Identities = 396/905 (43%), Positives = 556/905 (61%), Gaps = 35/905 (3%)
Query: 14 YPDLVIDVGEVTLGEENRKKLQKT-QRDQERARVIRAACALLNSGGGVIQMEMANR--DE 70
YP++++DVG V GEENRKK+ + + E +R+IRA CALLNSGGGVI+ E+ ++
Sbjct: 12 YPEVIVDVGRVIFGEENRKKMTNSCLKRSENSRIIRAICALLNSGGGVIKAEIDDKTYSY 71
Query: 71 RPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKDGSFNSRICSL 130
+ +G DLE S +KL+ Q + + Q G IFVKSWS D F S RICSL
Sbjct: 72 QCHGLGQDLETSFQKLLPSGS-QKYLDYMQQGHNLLIFVKSWSPDVF----SLPLRICSL 126
Query: 131 SSSLYCRSGTSVLHMNSRQAFDFLKTK--ERQSKYNLINEGSPPSKIMKAVYQNISESNP 188
S+LY R TS +++++ A + L+ K Q + + P + + + +
Sbjct: 127 RSNLYRRDVTSAINLSASSALELLREKGFRAQRGRPRVKKLHPQQVLNRCIQEEEDMRIL 186
Query: 189 AYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANTEGGYLFIG 248
A E F+ D + Y E L+F ES +EFK+F+TK + ++ ++P Y+SAFANT+GGY+ IG
Sbjct: 187 ASEFFKKDKLMYKEKLNFTESTHVEFKRFTTKKVIPRIKEMLPHYVSAFANTQGGYVLIG 246
Query: 249 VDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVEVFCGKELY 308
VDDKS++V+GC E+V+PD LK I I KLP HFC KP+V ++TKI+ V+ L
Sbjct: 247 VDDKSKEVVGCKWEKVNPDLLKKEIENCIEKLPTFHFCCEKPKVNFTTKILNVYQKDVLD 306
Query: 309 GYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPDFAEAFESQ 368
GY+CVI+V+ FCCVVF+EAP SW++++ + LT E+WV M+D PP + S
Sbjct: 307 GYVCVIQVEPFCCVVFAEAPDSWIMKDNSVTRLTAEQWVVMMLDTQ-SAPPSLVTDYNSC 365
Query: 369 LSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQHEGLKELIH 428
L S S + P Y K + K LQ+HLFPV ++ PESL K+L H+ L+ L+
Sbjct: 366 LISSASSARKSPGYPIKVHKFKEALQRHLFPVTQEEVQFKPESLCKKLFSDHKELEGLMK 425
Query: 429 KQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQD-AEGQDYC 487
+ P SQGIVI SRSWA D+ +++ V+CDALLIA NS +LYTIL + + G +Y
Sbjct: 426 TLIHPCSQGIVIFSRSWAGDVGFRKEQNVLCDALLIAVNSPVVLYTILIDPNWPGGLEYA 485
Query: 488 TRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQHM 547
TA LKQKL +GGYTGKVC+ +++ LS S P+ YP SY LA + M
Sbjct: 486 RNTAHQLKQKLQTVGGYTGKVCIIPRLIHLSSTQS----RPGEIPLRYPRSYRLADEEEM 541
Query: 548 EALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFSRSLRKNRELFVHGLPGSGKTI 607
E LLQ+LV+V L RSLLSDQ+GCE NLL +Q ++ S SL+K RELF++ PG KT
Sbjct: 542 EDLLQALVVVSLSSRSLLSDQMGCEFFNLLIMEQSQLLSESLQKTRELFIYCFPGVRKTA 601
Query: 608 MAMKIMEKIRNVFHCEAHRILYVCENQPLRNFISDRNICRAETRETFLREKFEHIQHIVI 667
+A+KIMEKI+++FHC+ ILYVCE+ L++F++ + C+A TR+TF++ +F I+HIV+
Sbjct: 602 LAIKIMEKIKDLFHCKPKEILYVCESDSLKDFVTQQTTCQAVTRKTFMQGEFLKIKHIVM 661
Query: 668 DEAQNFRTEDGDWYRKAKTITQ-------REKDCPGVLWIFLDYFQTSHLGHSGLPPLSA 720
DE +NF ++ G+WY KAK IT E G+LW+FLD FQ H +GLPP SA
Sbjct: 662 DETENFCSKYGNWYMKAKNITHPKAKGTGSENLHHGILWLFLDPFQIHHADVNGLPPPSA 721
Query: 721 QYPREELTRVVRNADEIAEYIQQEMQLIIENPPINIPHGYLAILS-----EAKWVPGVPG 775
Q+PR+ +T + A EIA+ +++EM+ I ENPP N+ LA+ S EA +PG
Sbjct: 722 QFPRKTITSGIHCALEIAKVMKEEMKRIKENPPSNMSPDTLALFSETAYEEATCAQALPG 781
Query: 776 NTKIIKNFTLEQIVTYVADTCRCFFERGYSPKDVAVLVSTVTEVEQYQSKLLKAM----- 830
+ N T EQI YVA C F+ GY PKD+A+L + +Y+ LLKAM
Sbjct: 782 VCETKTNLTTEQIANYVARKCHSLFQCGYLPKDIAILCRRGEDRGRYRLALLKAMELIET 841
Query: 831 RKKMVVQLSDACDMLGVHIVLDSVRRFSGLERSIVFGIHPRTADPAILPNILICLASRAK 890
+ V S A + G HIVLDS+++FSGLER++VFG+ P +C ASRA
Sbjct: 842 HRPSEVVFSPATGVWGSHIVLDSIQQFSGLERTVVFGLSPECDQSEEFHK--LCFASRAI 899
Query: 891 QHLYI 895
+HLY+
Sbjct: 900 KHLYL 904
>gi|157388955 schlafen family member 12 [Homo sapiens]
Length = 578
Score = 377 bits (967), Expect = e-104
Identities = 227/565 (40%), Positives = 334/565 (59%), Gaps = 31/565 (5%)
Query: 7 SLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQ-RDQERARVIRAACALLNSGGGVIQMEM 65
S+ + +Y +LV+DVG VTLGE +RKK++ + R ++ V RA CALLNSGGGVI+ E+
Sbjct: 4 SVDLETNYAELVLDVGRVTLGENSRKKMKDCKLRKKQNESVSRAMCALLNSGGGVIKAEI 63
Query: 66 ANRDERPTE--MGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKDGSF 123
N D T+ +GLDLE S ++ + + + + Q+G F IFVKSWS + +
Sbjct: 64 ENEDYSYTKDGIGLDLENSFSNILLF--VPEYLDFMQNGNYFLIFVKSWSLN------TS 115
Query: 124 NSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVYQNI 183
RI +LSS+LY R TS MN+ A +FLK ++ + P + K +I
Sbjct: 116 GLRITTLSSNLYKRDITSAKVMNATAALEFLKDMKKTRGRLYLR----PELLAKRPCVDI 171
Query: 184 SESNP----AYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFAN 239
E N A F ++ E L+F ES +E K FST+ + Q ++ I+P+Y+SAFAN
Sbjct: 172 QEENNMKALAGVFFDRTELDRKEKLTFTESTHVEIKNFSTEKLLQRIKEILPQYVSAFAN 231
Query: 240 TEGGYLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIV 299
T+GGYLFIG+++ ++++G E D D L+ I ++I K+P+ HFC K ++ YS K +
Sbjct: 232 TDGGYLFIGLNE-DKEIIGFKAEMSDLDDLEREIEKSIRKMPVHHFCMEKKKINYSCKFL 290
Query: 300 EVFCGKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPP 359
V+ L GY+C ++V+ FCC VF++ P SW V++ + LT +EW++ M++A+P+F
Sbjct: 291 GVYDKGSLCGYVCALRVERFCCAVFAKEPDSWHVKDNRVMQLTRKEWIQFMVEAEPKFSS 350
Query: 360 DFAEAFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQ 419
+ E SQ++ S P+ LE + Q+H P G + TPE+L ++L LQ
Sbjct: 351 SYEEVI-SQINTSLPAPHSWPL-----LEWQR--QRHHCPGLSGRITYTPENLCRKLFLQ 402
Query: 420 HEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQ 479
HEGLK+LI ++M +G +I SRSW+VDL LQE V+CDALLI+Q+S P+LYT Q
Sbjct: 403 HEGLKQLICEEMDSVRKGSLIFSRSWSVDLGLQENHKVLCDALLISQDSPPVLYTFHMVQ 462
Query: 480 DAEGQDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASY 539
D E + Y T+TA TLKQKL +GGYT KVCV K+ LSPE S + YP SY
Sbjct: 463 DEEFKGYSTQTALTLKQKLAKIGGYTKKVCVMTKIFYLSPEGMTSCQYDLRSQVIYPESY 522
Query: 540 SLAGTQHMEALLQSLVIVLLGFRSL 564
++ LL++L L +SL
Sbjct: 523 YFTRRKY---LLKALFKALKRLKSL 544
>gi|222537745 schlafen family member 12-like [Homo sapiens]
Length = 617
Score = 371 bits (953), Expect = e-102
Identities = 216/555 (38%), Positives = 320/555 (57%), Gaps = 19/555 (3%)
Query: 7 SLGVYPSYPDLVIDVGEVTLGEENRKKLQKTQ-RDQERARVIRAACALLNSGGGVIQMEM 65
S+ + +Y +LV++VG VTLGE NRKK++ Q R Q+ V RA CALLNSGGGVI+ E+
Sbjct: 51 SIDLDTNYAELVLNVGRVTLGENNRKKMKDCQLRKQQNENVSRAVCALLNSGGGVIKAEV 110
Query: 66 ANR--DERPTEMGLDLEESLRKLIQYPYLQAFFETKQHGRCFYIFVKSWSGDPFLKDGSF 123
N+ + +GLDLE S ++ P++ F + Q+G F+IFVKSWS + +
Sbjct: 111 ENKGYSYKKDGIGLDLENSFSNML--PFVPNFLDFMQNGNYFHIFVKSWSLE------TS 162
Query: 124 NSRICSLSSSLYCRSGTSVLHMNSRQAFDFLKTKERQSKYNLINEGSPPSKIMKAVYQNI 183
+I +LSSSLY R TS MN+ A +FLK E+ + P + V +
Sbjct: 163 GPQIATLSSSLYKRDVTSAKVMNASAALEFLKDMEKTGGRAYLRPEFPAKRACVDVQEES 222
Query: 184 SESNPAYEVFQTDTIEYGEILSFPESPSIEFKQFSTKHIQQYVENIIPEYISAFANTEGG 243
+ A + F + Y E L+F ES +E K FST+ + Q + I+P+Y+SAFANT+GG
Sbjct: 223 NMEALAADFFNRTELGYKEKLTFTESTHVEIKNFSTEKLLQRITEILPQYVSAFANTDGG 282
Query: 244 YLFIGVDDKSRKVLGCAKEQVDPDSLKNVIARAISKLPIVHFCSSKPRVEYSTKIVEVFC 303
YLF+G+++ ++V+G E+ L+ V +I KLP+ HFC K + Y K + V+
Sbjct: 283 YLFVGLNE-DKEVIGFKAEKSYLTKLEEVTKNSIGKLPVHHFCVEKGTINYLCKFLGVYD 341
Query: 304 GKELYGYLCVIKVKAFCCVVFSEAPKSWMVREKYIRPLTTEEWVEKMMDADPEFPPDFAE 363
L GY+ ++V+ FCC VF++ P SW V++ ++ LT +EW++ M+D++P E
Sbjct: 342 KGRLCGYVYALRVERFCCAVFAKKPDSWHVKDNRVKQLTEKEWIQFMVDSEP-----VCE 396
Query: 364 AFESQLSLSDSPSLCRPVYSKKGLEHKADLQQHLFPVPPGHLECTPESLWKELSLQHEGL 423
S S S S P+ ++ + K ++ P + C P++ + L QHEGL
Sbjct: 397 ELPSPASTSSPVSQSYPL--REYINFKIQPLRYHLPGLSEKITCAPKTFCRNLFSQHEGL 454
Query: 424 KELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILREQDAEG 483
K+LI ++M ++G +I SRSW++DL LQE V+CDALLI+Q+ P+LYT QD E
Sbjct: 455 KQLICEEMGSVNKGSLIFSRSWSLDLGLQENHKVLCDALLISQDKPPVLYTFHMVQDEEF 514
Query: 484 QDYCTRTAFTLKQKLVNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAG 543
+DY T+TA TLKQKL +GGYT KVCV K+ LSPE S + YP SY
Sbjct: 515 KDYSTQTAQTLKQKLAKIGGYTKKVCVMTKIFYLSPEGKTSCQYDLNSQVIYPESYYWTT 574
Query: 544 TQHMEALLQSLVIVL 558
Q M+ L ++L +L
Sbjct: 575 AQTMKDLEKALSNIL 589
Score = 66.6 bits (161), Expect = 1e-10
Identities = 30/33 (90%), Positives = 32/33 (96%)
Query: 608 MAMKIMEKIRNVFHCEAHRILYVCENQPLRNFI 640
MAMKIMEKIRNVFHCEAHRILY+CE+Q LRNFI
Sbjct: 1 MAMKIMEKIRNVFHCEAHRILYICESQFLRNFI 33
>gi|45267821 schlafen-like 1 [Homo sapiens]
Length = 407
Score = 38.1 bits (87), Expect = 0.037
Identities = 16/44 (36%), Positives = 30/44 (68%)
Query: 208 ESPSIEFKQFSTKHIQQYVENIIPEYISAFANTEGGYLFIGVDD 251
E+ ++EFK+ S +++ ++ + Y+ AF N+EGG L +GV+D
Sbjct: 221 ETRNMEFKRGSGEYLSLAFKHHVRRYVCAFLNSEGGSLLVGVED 264
>gi|122937434 Rho-guanine nucleotide exchange factor [Homo sapiens]
Length = 1651
Score = 35.4 bits (80), Expect = 0.24
Identities = 18/51 (35%), Positives = 25/51 (49%)
Query: 499 VNMGGYTGKVCVRAKVLCLSPESSAEALEAAVSPMDYPASYSLAGTQHMEA 549
+N+ G T ++ L P+SS L SP YP S ++ GT H EA
Sbjct: 391 INIEGITATTSPESRGCTLWPQSSKHTLPTETSPSVYPLSENVEGTAHTEA 441
>gi|223890153 DSN1, MIND kinetochore complex component, homolog
isoform 3 [Homo sapiens]
Length = 340
Score = 33.5 bits (75), Expect = 0.91
Identities = 65/269 (24%), Positives = 109/269 (40%), Gaps = 39/269 (14%)
Query: 366 ESQLSLSDSPSLCRPVYSKKG----LEHKADLQQ---HLFPVPPGHLECTPESLWKELSL 418
E ++ L SP KKG L H+ LQ HL P W+ S+
Sbjct: 34 EERIHLGSSP--------KKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASM 85
Query: 419 QHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
+ ++ +H P QGI LSRS +VDL ++ G C L Q S L LR+
Sbjct: 86 KETNRRKSLH----PIHQGITELSRSISVDLAESKRLG--CLLLSSFQFSIQKLEPFLRD 139
Query: 479 QDAEGQDYCTRTAFTLKQKLVNMG-GYTGKVCVRAKVLCLSPESSAEALEAAVSPM-DYP 536
+ A +L ++L + G ++ + ++S +LEA+V+ M +Y
Sbjct: 140 TKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYI 199
Query: 537 ASYSLAGTQHMEALL----QSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFS-----R 587
+SL + LL ++ I+ G ++ E + L + Q E+ + +
Sbjct: 200 TKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQ 259
Query: 588 SLRKNR-------ELFVHGLPGSGKTIMA 609
+ +N+ EL + L GS K + A
Sbjct: 260 KILQNQSKVFDCMELVMDELQGSVKQLQA 288
>gi|223890149 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 33.5 bits (75), Expect = 0.91
Identities = 65/269 (24%), Positives = 109/269 (40%), Gaps = 39/269 (14%)
Query: 366 ESQLSLSDSPSLCRPVYSKKG----LEHKADLQQ---HLFPVPPGHLECTPESLWKELSL 418
E ++ L SP KKG L H+ LQ HL P W+ S+
Sbjct: 50 EERIHLGSSP--------KKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASM 101
Query: 419 QHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
+ ++ +H P QGI LSRS +VDL ++ G C L Q S L LR+
Sbjct: 102 KETNRRKSLH----PIHQGITELSRSISVDLAESKRLG--CLLLSSFQFSIQKLEPFLRD 155
Query: 479 QDAEGQDYCTRTAFTLKQKLVNMG-GYTGKVCVRAKVLCLSPESSAEALEAAVSPM-DYP 536
+ A +L ++L + G ++ + ++S +LEA+V+ M +Y
Sbjct: 156 TKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYI 215
Query: 537 ASYSLAGTQHMEALL----QSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFS-----R 587
+SL + LL ++ I+ G ++ E + L + Q E+ + +
Sbjct: 216 TKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQ 275
Query: 588 SLRKNR-------ELFVHGLPGSGKTIMA 609
+ +N+ EL + L GS K + A
Sbjct: 276 KILQNQSKVFDCMELVMDELQGSVKQLQA 304
>gi|223890147 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 33.5 bits (75), Expect = 0.91
Identities = 65/269 (24%), Positives = 109/269 (40%), Gaps = 39/269 (14%)
Query: 366 ESQLSLSDSPSLCRPVYSKKG----LEHKADLQQ---HLFPVPPGHLECTPESLWKELSL 418
E ++ L SP KKG L H+ LQ HL P W+ S+
Sbjct: 50 EERIHLGSSP--------KKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASM 101
Query: 419 QHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
+ ++ +H P QGI LSRS +VDL ++ G C L Q S L LR+
Sbjct: 102 KETNRRKSLH----PIHQGITELSRSISVDLAESKRLG--CLLLSSFQFSIQKLEPFLRD 155
Query: 479 QDAEGQDYCTRTAFTLKQKLVNMG-GYTGKVCVRAKVLCLSPESSAEALEAAVSPM-DYP 536
+ A +L ++L + G ++ + ++S +LEA+V+ M +Y
Sbjct: 156 TKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYI 215
Query: 537 ASYSLAGTQHMEALL----QSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFS-----R 587
+SL + LL ++ I+ G ++ E + L + Q E+ + +
Sbjct: 216 TKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQ 275
Query: 588 SLRKNR-------ELFVHGLPGSGKTIMA 609
+ +N+ EL + L GS K + A
Sbjct: 276 KILQNQSKVFDCMELVMDELQGSVKQLQA 304
>gi|223972618 DSN1, MIND kinetochore complex component, homolog
isoform 1 [Homo sapiens]
Length = 356
Score = 33.5 bits (75), Expect = 0.91
Identities = 65/269 (24%), Positives = 109/269 (40%), Gaps = 39/269 (14%)
Query: 366 ESQLSLSDSPSLCRPVYSKKG----LEHKADLQQ---HLFPVPPGHLECTPESLWKELSL 418
E ++ L SP KKG L H+ LQ HL P W+ S+
Sbjct: 50 EERIHLGSSP--------KKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASM 101
Query: 419 QHEGLKELIHKQMRPFSQGIVILSRSWAVDLNLQEKPGVICDALLIAQNSTPILYTILRE 478
+ ++ +H P QGI LSRS +VDL ++ G C L Q S L LR+
Sbjct: 102 KETNRRKSLH----PIHQGITELSRSISVDLAESKRLG--CLLLSSFQFSIQKLEPFLRD 155
Query: 479 QDAEGQDYCTRTAFTLKQKLVNMG-GYTGKVCVRAKVLCLSPESSAEALEAAVSPM-DYP 536
+ A +L ++L + G ++ + ++S +LEA+V+ M +Y
Sbjct: 156 TKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYI 215
Query: 537 ASYSLAGTQHMEALL----QSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIFS-----R 587
+SL + LL ++ I+ G ++ E + L + Q E+ + +
Sbjct: 216 TKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQ 275
Query: 588 SLRKNR-------ELFVHGLPGSGKTIMA 609
+ +N+ EL + L GS K + A
Sbjct: 276 KILQNQSKVFDCMELVMDELQGSVKQLQA 304
>gi|32307166 Rho guanine exchange factor 15 [Homo sapiens]
Length = 841
Score = 33.5 bits (75), Expect = 0.91
Identities = 35/151 (23%), Positives = 64/151 (42%), Gaps = 18/151 (11%)
Query: 277 ISKLPIVHFCSSKPRVEYSTKIVEVFCGKELYGYLCVIKVKAFCCVVFSEA-----PKSW 331
+ LP+V S R+E+ ++ E+ C + + + C ++FS+ PKS
Sbjct: 623 VKALPLV---SWSRRLEFQGELTELGCRRGGVLFASRPRFTPLCLLLFSDLLLITQPKSG 679
Query: 332 MVREKYIRPLTTEEWVEKMMDADPEFPPDFAEAFESQLSLSDSPSLCRPVYSKKGLEHKA 391
+ + V+ DP PP F +LSL + RP + +
Sbjct: 680 --QRLQVLDYAHRSLVQAQQVPDPSGPPTF------RLSLLSNHQ-GRPTHRLLQASSLS 730
Query: 392 DLQQHLFPVP-PGHLECTPESLWKELSLQHE 421
D+Q+ L P PG L C+P++++++ E
Sbjct: 731 DMQRWLGAFPTPGPLPCSPDTIYEDCDCSQE 761
>gi|114205399 cyclic nucleotide gated channel beta 1 isoform a [Homo
sapiens]
Length = 1251
Score = 32.3 bits (72), Expect = 2.0
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 6/94 (6%)
Query: 806 PKDVAVLVSTVTEVEQYQSKLLKAMRKKMVVQLSDACDM-LGVHI---VLDSVRRFSGLE 861
PK V V T E + +L +++VQL D + L + + ++ V F G +
Sbjct: 910 PKSVQNRVKTWYEYTWHSQGMLD--ESELMVQLPDKMRLDLAIDVNYNIVSKVALFQGCD 967
Query: 862 RSIVFGIHPRTADPAILPNILICLASRAKQHLYI 895
R ++F + R LPN +C + +YI
Sbjct: 968 RQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYI 1001
>gi|28144897 adenylate kinase 5 isoform 1 [Homo sapiens]
Length = 562
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 526 LEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIF 585
+ AV +P + AG+ ++ + ++ S DQ G + LN+ F
Sbjct: 311 ISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQ-GDDQLNVFGEDTMGGF 369
Query: 586 SRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
LRK + +F+ G PGSGK K++EK
Sbjct: 370 MEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 399
Score = 30.4 bits (67), Expect = 7.7
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 580 QQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
++YE+F + + + + V G PGSGK ++KI E+
Sbjct: 120 EEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAER 155
>gi|28144899 adenylate kinase 5 isoform 2 [Homo sapiens]
Length = 536
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/90 (27%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 526 LEAAVSPMDYPASYSLAGTQHMEALLQSLVIVLLGFRSLLSDQLGCEVLNLLTAQQYEIF 585
+ AV +P + AG+ ++ + ++ S DQ G + LN+ F
Sbjct: 285 ISMAVDNKLFPNKEAAAGSSDLDPSMILDTGEIIDTGSDYEDQ-GDDQLNVFGEDTMGGF 343
Query: 586 SRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
LRK + +F+ G PGSGK K++EK
Sbjct: 344 MEDLRKCKIIFIIGGPGSGKGTQCEKLVEK 373
Score = 30.4 bits (67), Expect = 7.7
Identities = 13/36 (36%), Positives = 23/36 (63%)
Query: 580 QQYEIFSRSLRKNRELFVHGLPGSGKTIMAMKIMEK 615
++YE+F + + + + V G PGSGK ++KI E+
Sbjct: 94 EEYEVFDPTRPRPKIILVIGGPGSGKGTQSLKIAER 129
>gi|194018490 ATPase family, AAA domain containing 3C [Homo sapiens]
Length = 411
Score = 32.0 bits (71), Expect = 2.6
Identities = 15/33 (45%), Positives = 23/33 (69%), Gaps = 4/33 (12%)
Query: 584 IFSRSLRKNRELFVH----GLPGSGKTIMAMKI 612
I +R+++KNR L+ H G PG+GKT+ A K+
Sbjct: 158 IMTRNIKKNRGLYRHILLYGPPGTGKTLFAKKL 190
>gi|33667040 NLR family, pyrin domain containing 8 [Homo sapiens]
Length = 1048
Score = 30.8 bits (68), Expect = 5.9
Identities = 17/38 (44%), Positives = 25/38 (65%), Gaps = 3/38 (7%)
Query: 590 RKNRELFVHGLPGSGKTIMAMKIM-EKIRNVFHCEAHR 626
R+ + + + G PG GKTI+A K+M E RN F+ AH+
Sbjct: 201 RQPKTVAIQGAPGIGKTILAKKVMFEWARNKFY--AHK 236
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.406
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,640,852
Number of Sequences: 37866
Number of extensions: 1549117
Number of successful extensions: 3904
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 3832
Number of HSP's gapped (non-prelim): 26
length of query: 897
length of database: 18,247,518
effective HSP length: 111
effective length of query: 786
effective length of database: 14,044,392
effective search space: 11038892112
effective search space used: 11038892112
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.