Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 56118219
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
(556 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|56118219 insulin-like growth factor 2 mRNA binding protein 2 ... 1097 0.0
gi|64085377 insulin-like growth factor 2 mRNA binding protein 2 ... 1077 0.0
gi|56237027 insulin-like growth factor 2 mRNA binding protein 1 ... 744 0.0
gi|30795212 insulin-like growth factor 2 mRNA binding protein 3 ... 719 0.0
gi|238624257 insulin-like growth factor 2 mRNA binding protein 1... 400 e-111
gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens] 88 2e-17
gi|100816392 far upstream element (FUSE) binding protein 3 [Homo... 86 9e-17
gi|17402900 far upstream element-binding protein [Homo sapiens] 78 2e-14
gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens] 77 3e-14
gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo ... 77 4e-14
gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens] 77 4e-14
gi|222352151 poly(rC) binding protein 1 [Homo sapiens] 76 7e-14
gi|154355000 KH-type splicing regulatory protein [Homo sapiens] 75 1e-13
gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo ... 74 4e-13
gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens] 74 4e-13
gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens] 74 4e-13
gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens] 74 4e-13
gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens] 74 4e-13
gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens] 74 4e-13
gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens] 74 4e-13
gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens] 74 4e-13
gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens] 73 8e-13
gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens] 73 8e-13
gi|4885409 high density lipoprotein binding protein [Homo sapiens] 69 1e-11
gi|42716280 high density lipoprotein binding protein [Homo sapiens] 69 1e-11
gi|145312259 tudor and KH domain containing isoform a [Homo sapi... 61 2e-09
gi|145312270 tudor and KH domain containing isoform a [Homo sapi... 61 2e-09
gi|145312256 tudor and KH domain containing isoform a [Homo sapi... 61 2e-09
gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a ... 54 3e-07
gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b ... 54 3e-07
>gi|56118219 insulin-like growth factor 2 mRNA binding protein 2
isoform b [Homo sapiens]
Length = 556
Score = 1097 bits (2838), Expect = 0.0
Identities = 556/556 (100%), Positives = 556/556 (100%)
Query: 1 MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG 60
MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG
Sbjct: 1 MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG 60
Query: 61 KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET 120
KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET
Sbjct: 61 KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET 120
Query: 121 AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG 180
AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG
Sbjct: 121 AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG 180
Query: 181 HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK 240
HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK
Sbjct: 181 HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK 240
Query: 241 PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI 300
PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI
Sbjct: 241 PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI 300
Query: 301 EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHS 360
EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHS
Sbjct: 301 EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHS 360
Query: 361 GYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKI 420
GYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKI
Sbjct: 361 GYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKI 420
Query: 421 APAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGR 480
APAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGR
Sbjct: 421 APAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGR 480
Query: 481 VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 540
VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK
Sbjct: 481 VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 540
Query: 541 QQEQKYPQGVASQRSK 556
QQEQKYPQGVASQRSK
Sbjct: 541 QQEQKYPQGVASQRSK 556
>gi|64085377 insulin-like growth factor 2 mRNA binding protein 2
isoform a [Homo sapiens]
Length = 599
Score = 1077 bits (2784), Expect = 0.0
Identities = 556/599 (92%), Positives = 556/599 (92%), Gaps = 43/599 (7%)
Query: 1 MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG 60
MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG
Sbjct: 1 MMNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSG 60
Query: 61 KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET 120
KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET
Sbjct: 61 KVELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTET 120
Query: 121 AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG 180
AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG
Sbjct: 121 AVVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQG 180
Query: 181 HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK 240
HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK
Sbjct: 181 HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEK 240
Query: 241 PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI 300
PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI
Sbjct: 241 PVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKI 300
Query: 301 EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN--- 357
EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN
Sbjct: 301 EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNQQA 360
Query: 358 ----------------------------------------THSGYFSSLYPHHQFGPFPH 377
THSGYFSSLYPHHQFGPFPH
Sbjct: 361 NLIPGLNLSALGIFSTGLSVLSPPAGPRGAPPAAPYHPFTTHSGYFSSLYPHHQFGPFPH 420
Query: 378 HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG 437
HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG
Sbjct: 421 HHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITG 480
Query: 438 PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS 497
PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS
Sbjct: 481 PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTS 540
Query: 498 AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 556
AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK
Sbjct: 541 AEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 599
>gi|56237027 insulin-like growth factor 2 mRNA binding protein 1
isoform 1 [Homo sapiens]
Length = 577
Score = 744 bits (1922), Expect = 0.0
Identities = 383/579 (66%), Positives = 458/579 (79%), Gaps = 26/579 (4%)
Query: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
MNKLYIGNL+ +VT DL ++F + K+ +GQ L+KSGYAFVD PD++WA++AIET SGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
VEL GK +E+++SV KK RSRKIQIRNIPP L+WEVLD LLAQYGTVEN EQVNT++ETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGH 181
VVNVTY+ RE+ + A+ KL+GHQ EN++ K+SYIPDE+++ P+ +RG SR Q
Sbjct: 121 VVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIAQG--PENGRRGGFGSRGQPR 178
Query: 182 -----APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSG 236
A G ++ +Q+D PLR+LVPTQ+VGAIIGKEG TI+NITKQTQS++D+HRKEN+G
Sbjct: 179 QGSPVAAGAPAKQQQVDIPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAG 238
Query: 237 AAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRN 296
AAEK +++H+TPEG S AC+MILEIM KEA +TK A+E+PLKILAHN VGRLIGKEGRN
Sbjct: 239 AAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRN 298
Query: 297 LKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAV 356
LKK+E +T TKITISSLQDL++YNPERTITVKG +E C AE EIMKK+REA+END+ A+
Sbjct: 299 LKKVEQDTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAM 358
Query: 357 NTHS-----------GYF---SSLYPHHQFG-----PFPHHHSYPEQEIVNLFIPTQAVG 397
+ S G F SS P P+ PEQE+V +FIP QAVG
Sbjct: 359 SLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVG 418
Query: 398 AIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEEN 457
AIIGKKG HIKQL+RFA ASIKIAP E PD RMVIITGPPEAQFKAQGRI+GKLKEEN
Sbjct: 419 AIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEEN 478
Query: 458 FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVR 517
FF PKEEVKLE HIRVP+S AGRVIGKGGKTVNELQNLT+AEV+VPRDQTPDEN++VIV+
Sbjct: 479 FFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVK 538
Query: 518 IIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 556
IIGHF+ASQ AQRKIR+I+ QVKQQ QK A R K
Sbjct: 539 IIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 577
>gi|30795212 insulin-like growth factor 2 mRNA binding protein 3
[Homo sapiens]
Length = 579
Score = 719 bits (1856), Expect = 0.0
Identities = 369/567 (65%), Positives = 445/567 (78%), Gaps = 24/567 (4%)
Query: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
MNKLYIGNLS DL +F D K+P++G L+K+GYAFVD PD++WA++AIE LSGK
Sbjct: 1 MNKLYIGNLSENAAPSDLESIFKDAKIPVSGPFLVKTGYAFVDCPDESWALKAIEALSGK 60
Query: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
+ELHGK +EV++SV K+ R RK+QIRNIPPHLQWEVLD LL QYG VE+ EQVNTD+ETA
Sbjct: 61 IELHGKPIEVEHSVPKRQRIRKLQIRNIPPHLQWEVLDSLLVQYGVVESCEQVNTDSETA 120
Query: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQ----RAQRGDHSSR 177
VVNVTY+++++A+ A++KL+G Q EN++ K++YIPDE + +P Q R G S
Sbjct: 121 VVNVTYSSKDQARQALDKLNGFQLENFTLKVAYIPDEMAAQQNPLQQPRGRRGLGQRGSS 180
Query: 178 EQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA 237
QG +PG S+ + D PLR+LVPTQFVGAIIGKEG TI+NITKQTQS++D+HRKEN+GA
Sbjct: 181 RQG-SPGSVSKQKPCDLPLRLLVPTQFVGAIIGKEGATIRNITKQTQSKIDVHRKENAGA 239
Query: 238 AEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNL 297
AEK +TI +TPEGTS AC+ ILEIM KEA + K EEIPLKILAHN VGRLIGKEGRNL
Sbjct: 240 AEKSITILSTPEGTSAACKSILEIMHKEAQDIKFTEEIPLKILAHNNFVGRLIGKEGRNL 299
Query: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
KKIE +T TKITIS LQ+L++YNPERTITVKG VE CA AE EIMKK+RE++END+ ++N
Sbjct: 300 KKIEQDTDTKITISPLQELTLYNPERTITVKGNVETCAKAEEEIMKKIRESYENDIASMN 359
Query: 358 THS-----------GYF---SSLYPHHQFGPFPHHHSYP-----EQEIVNLFIPTQAVGA 398
+ G F S + P P YP E E V+LFIP +VGA
Sbjct: 360 LQAHLIPGLNLNALGLFPPTSGMPPPTSGPPSAMTPPYPQFEQSETETVHLFIPALSVGA 419
Query: 399 IIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENF 458
IIGK+G HIKQL+RFAGASIKIAPAE PD RMVIITGPPEAQFKAQGRI+GK+KEENF
Sbjct: 420 IIGKQGQHIKQLSRFAGASIKIAPAEAPDAKVRMVIITGPPEAQFKAQGRIYGKIKEENF 479
Query: 459 FNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRI 518
+PKEEVKLEAHIRVPS AGRVIGKGGKTVNELQNL+SAEV+VPRDQTPDEN++V+V+I
Sbjct: 480 VSPKEEVKLEAHIRVPSFAAGRVIGKGGKTVNELQNLSSAEVVVPRDQTPDENDQVVVKI 539
Query: 519 IGHFFASQTAQRKIREIVQQVKQQEQK 545
GHF+A Q AQRKI+EI+ QVKQ +Q+
Sbjct: 540 TGHFYACQVAQRKIQEILTQVKQHQQQ 566
>gi|238624257 insulin-like growth factor 2 mRNA binding protein 1
isoform 2 [Homo sapiens]
Length = 438
Score = 400 bits (1029), Expect = e-111
Identities = 213/333 (63%), Positives = 249/333 (74%), Gaps = 19/333 (5%)
Query: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
T+ + +E+ ++ + ++T+ A+E+PLKILAHN VGRLIGKEGRNLKK+E
Sbjct: 106 TVENCEQVNTESETAVVNVTYSNREQTRQADEVPLKILAHNNFVGRLIGKEGRNLKKVEQ 165
Query: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHS-- 360
+T TKITISSLQDL++YNPERTITVKG +E C AE EIMKK+REA+END+ A++ S
Sbjct: 166 DTETKITISSLQDLTLYNPERTITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHL 225
Query: 361 ---------GYF---SSLYPHHQFG-----PFPHHHSYPEQEIVNLFIPTQAVGAIIGKK 403
G F SS P P+ PEQE+V +FIP QAVGAIIGKK
Sbjct: 226 IPGLNLAAVGLFPASSSAVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKK 285
Query: 404 GAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKE 463
G HIKQL+RFA ASIKIAP E PD RMVIITGPPEAQFKAQGRI+GKLKEENFF PKE
Sbjct: 286 GQHIKQLSRFASASIKIAPPETPDSKVRMVIITGPPEAQFKAQGRIYGKLKEENFFGPKE 345
Query: 464 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 523
EVKLE HIRVP+S AGRVIGKGGKTVNELQNLT+AEV+VPRDQTPDEN++VIV+IIGHF+
Sbjct: 346 EVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFY 405
Query: 524 ASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 556
ASQ AQRKIR+I+ QVKQQ QK A R K
Sbjct: 406 ASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 438
Score = 219 bits (559), Expect = 4e-57
Identities = 169/503 (33%), Positives = 241/503 (47%), Gaps = 144/503 (28%)
Query: 2 MNKLYIGNLSPAVTADDLRQLFGDRKLPLAGQVLLKSGYAFVDYPDQNWAIRAIETLSGK 61
MNKLYIGNL+ +VT DL ++F + K+ +GQ L+KSGYAFVD PD++WA++AIET SGK
Sbjct: 1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGK 60
Query: 62 VELHGKIMEVDYSVSKKLRSRKIQIRNIPPHLQWEVLDGLLAQYGTVENVEQVNTDTETA 121
VEL GK +E+++SV KK RSRKIQIRNIPP L+WEVLD LLAQYGTVEN EQVNT++ETA
Sbjct: 61 VELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETA 120
Query: 122 VVNVTYATREEAKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGH 181
VVNVTY S+REQ
Sbjct: 121 VVNVTY-----------------------------------------------SNREQ-- 131
Query: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGA--AE 239
T QA ++ PL+IL FVG +IGKEG +K + + T++++ I ++ E
Sbjct: 132 ----TRQADEV--PLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPE 185
Query: 240 KPVTIHATPEGTSEACRMILEIMQK--EADETKLA------EEIPLKILAHNGL------ 285
+ +T+ E CR EIM+K EA E +A IP LA GL
Sbjct: 186 RTITVKGAIE---NCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSS 242
Query: 286 -----------------------------------VGRLIGKEGRNLKKIEHETGTKITI 310
VG +IGK+G+++K++ I I
Sbjct: 243 AVPPPPSSVTGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKI 302
Query: 311 SSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHH 370
+ + + R + + G EA A+ I KL+E +
Sbjct: 303 APPETPD--SKVRMVIITGPPEAQFKAQGRIYGKLKE---------------------EN 339
Query: 371 QFGPFPHHHSYPEQEI---VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD 427
FG P++E+ ++ +P A G +IGK G + +L A + + + PD
Sbjct: 340 FFG--------PKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAEVVVPRDQTPD 391
Query: 428 VSERMVI-ITGPPEAQFKAQGRI 449
++++++ I G A AQ +I
Sbjct: 392 ENDQVIVKIIGHFYASQMAQRKI 414
>gi|194306633 poly(rC) binding protein 3 isoform 2 [Homo sapiens]
Length = 345
Score = 88.2 bits (217), Expect = 2e-17
Identities = 89/341 (26%), Positives = 153/341 (44%), Gaps = 50/341 (14%)
Query: 153 SYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKE 212
S +P +S+ S + Q G E + GG + + +R+L+ + VG+IIGK+
Sbjct: 11 SVLPHSTLSTLSHHPQPQFGRRM--ESKVSEGGLN----VTLTIRLLMHGKEVGSIIGKK 64
Query: 213 GLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL-----EIMQKEAD 267
G T+K + +++ +R++I E+ VTI + +A MI +I+ ++
Sbjct: 65 GETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
Query: 268 ETKLAE-EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
++ + L+++ G LIGK G +K+I TG ++ ++ D+ + ER +T
Sbjct: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVT 179
Query: 327 VKGTVEACASAEIEIMKKLREAF---------ENDMLAVNTHSGYFSSLYPHHQFGP--- 374
+ GT +A +I + EA+ D+ ++ + + P Q P
Sbjct: 180 ISGTPDAIIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFP 239
Query: 375 ---FPHHHSYPEQEIV---------------NLFIPTQAVGAIIGKKGAHIKQLARFAGA 416
P H S Q ++ L IP +G IIG++G I ++ + +GA
Sbjct: 240 GEKLPLHSSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGA 299
Query: 417 SIKIAPA-EGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 456
IKIA A EG SER + ITG P AQ I +L E
Sbjct: 300 QIKIANATEGS--SERQITITGTPANISLAQYLINARLTSE 338
Score = 76.3 bits (186), Expect = 7e-14
Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER+V ITGP +A FKA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPTDAIFKAF 104
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I K +E+ + N K +R VP+S G +IGKGG + E++ T A+V
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
Query: 502 VPRDQTPDENEEVI 515
V D P+ E +
Sbjct: 165 VAGDMLPNSTERAV 178
Score = 75.1 bits (183), Expect = 2e-13
Identities = 69/295 (23%), Positives = 119/295 (40%), Gaps = 82/295 (27%)
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M+ + E L + +++L H VG +IGK+G +KK+ E+G +I IS P
Sbjct: 33 MESKVSEGGLNVTLTIRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNC-----P 87
Query: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSY 381
ER +T+ G +A A I K FE D+ +N+ S ++ P
Sbjct: 88 ERIVTITGPTDAIFKAFAMIAYK----FEEDI--INSMSNSPATSKP------------- 128
Query: 382 PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
+ L +P G++IGK G+ IK++ GA +++A P+ +ER V I+G P+A
Sbjct: 129 --PVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAGDMLPNSTERAVTISGTPDA 186
Query: 442 ---------------------------------QFKAQGRIFGKLKEENFFNPKEEVKLE 468
Q Q F L + N P E++ L
Sbjct: 187 IIQCVKQICVVMLEAYTIQGQYAIPHPDLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLH 246
Query: 469 A-----------------------HIRVPSSTAGRVIGKGGKTVNELQNLTSAEV 500
+ + +P+ G +IG+ G +NE++ ++ A++
Sbjct: 247 SSEEAQNLMGQSSGLDASPPASTHELTIPNDLIGCIIGRQGTKINEIRQMSGAQI 301
>gi|100816392 far upstream element (FUSE) binding protein 3 [Homo
sapiens]
Length = 572
Score = 85.9 bits (211), Expect = 9e-17
Identities = 82/339 (24%), Positives = 146/339 (43%), Gaps = 50/339 (14%)
Query: 200 VPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL 259
VP + VG IIG+ G I I ++ ++ I E+SG E+P + TPE +A R++
Sbjct: 84 VPDKMVGFIIGRGGEQISRIQAESGCKIQI-ASESSGIPERPCVLTGTPESIEQAKRLLG 142
Query: 260 EIMQKEADETKLAEEIPL-----KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQ 314
+I+ + + +I +IL VG +IG+ G +K+++ TG K+ + +Q
Sbjct: 143 QIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGGETIKQLQERTGVKMVM--IQ 200
Query: 315 DLSI-YNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFG 373
D + ++ + + G A +++ +RE + D V G F+S
Sbjct: 201 DGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRGVR---GDFNSRMGGGS-- 255
Query: 374 PFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMV 433
+ + +P AVG +IG+ G IK++ AG I+ P +G ER
Sbjct: 256 -------------IEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKPDDGIS-PERAA 301
Query: 434 IITGPPEAQFKAQGRIFGKL----KEENFFNPKEEVK-----------------LEAHIR 472
+ GPP+ + + I +L +E + F + E
Sbjct: 302 QVMGPPD-RCQHAAHIISELILTAQERDGFGGLAAARGRGRGRGDWSVGAPGGVQEITYT 360
Query: 473 VPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN 511
VP+ G VIGKGG+ + + + A V + R+ P+ +
Sbjct: 361 VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSD 399
Score = 79.0 bits (193), Expect = 1e-14
Identities = 53/190 (27%), Positives = 97/190 (51%), Gaps = 10/190 (5%)
Query: 370 HQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 429
+Q G H + +E +P + VG IIG+ G I ++ +G I+IA +E +
Sbjct: 66 NQLGALVHQRTVITEEFK---VPDKMVGFIIGRGGEQISRIQAESGCKIQIA-SESSGIP 121
Query: 430 ERMVIITGPPEAQFKAQGRIFGKLKEE-----NFFNPKEEVKLEAHIRVPSSTAGRVIGK 484
ER ++TG PE+ +A+ R+ G++ + F N + I +P+S G VIG+
Sbjct: 122 ERPCVLTGTPESIEQAK-RLLGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGR 180
Query: 485 GGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
GG+T+ +LQ T ++++ +D + +RI G F Q A+ + EI+++ Q +
Sbjct: 181 GGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADF 240
Query: 545 KYPQGVASQR 554
+ +G + R
Sbjct: 241 RGVRGDFNSR 250
Score = 67.8 bits (164), Expect = 3e-11
Identities = 68/255 (26%), Positives = 113/255 (44%), Gaps = 21/255 (8%)
Query: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSR-VDIHRKENSGAAEKPVTIHATPEGTSEACR 256
IL+P VG +IG+ G TIK + ++T + V I A+KP+ I +A
Sbjct: 167 ILIPASKVGLVIGRGGETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQARE 226
Query: 257 MILEIMQK--EADETKLAEEI-------PLKILAHNGLVGRLIGKEGRNLKKIEHETGTK 307
M+LEI+++ +AD + + +++ VG +IG+ G +KKI+++ G +
Sbjct: 227 MVLEIIREKDQADFRGVRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVR 286
Query: 308 ITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLY 367
I +S PER V G + C A I + + A E D G ++
Sbjct: 287 IQFKPDDGIS---PERAAQVMGPPDRCQHAAHIISELILTAQERDGFG-----GLAAARG 338
Query: 368 PHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA--PAEG 425
G + QEI +P G +IGK G +IK + + +GA +++ P
Sbjct: 339 RGRGRGDWSVGAPGGVQEITYT-VPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPN 397
Query: 426 PDVSERMVIITGPPE 440
D + R I G P+
Sbjct: 398 SDPNLRRFTIRGVPQ 412
Score = 57.4 bits (137), Expect = 3e-08
Identities = 69/283 (24%), Positives = 119/283 (42%), Gaps = 42/283 (14%)
Query: 285 LVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKK 344
+VG +IG+ G + +I+ E+G KI I+S S PER + GT E+ IE K+
Sbjct: 88 MVGFIIGRGGEQISRIQAESGCKIQIASE---SSGIPERPCVLTGTPES-----IEQAKR 139
Query: 345 LREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKG 404
L + + GP H+ I + IP VG +IG+ G
Sbjct: 140 L-----------------LGQIVDRCRNGPGFHNDIDSNSTIQEILIPASKVGLVIGRGG 182
Query: 405 AHIKQLARFAGAS-IKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEEN---FFN 460
IKQL G + I P +++ + ITG +A+ + ++E++ F
Sbjct: 183 ETIKQLQERTGVKMVMIQDGPLPTGADKPLRITGDAFKVQQAREMVLEIIREKDQADFRG 242
Query: 461 PKEEVKLEA-----HIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDE--NEE 513
+ + + VP G VIG+ G+ + ++QN + PD+ + E
Sbjct: 243 VRGDFNSRMGGGSIEVSVPRFAVGIVIGRNGEMIKKIQNDAGVRI----QFKPDDGISPE 298
Query: 514 VIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGVASQRSK 556
+++G Q A I E++ + QE+ G+A+ R +
Sbjct: 299 RAAQVMGPPDRCQHAAHIISELI--LTAQERDGFGGLAAARGR 339
Score = 35.4 bits (80), Expect = 0.14
Identities = 25/81 (30%), Positives = 38/81 (46%), Gaps = 9/81 (11%)
Query: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRK--ENSGAAE 239
APGG + + VP G +IGK G IK+I +Q+ + V++ R NS
Sbjct: 350 APGGVQE-------ITYTVPADKCGLVIGKGGENIKSINQQSGAHVELQRNPPPNSDPNL 402
Query: 240 KPVTIHATPEGTSEACRMILE 260
+ TI P+ A ++I E
Sbjct: 403 RRFTIRGVPQQIEVARQLIDE 423
>gi|17402900 far upstream element-binding protein [Homo sapiens]
Length = 644
Score = 78.2 bits (191), Expect = 2e-14
Identities = 92/407 (22%), Positives = 163/407 (40%), Gaps = 60/407 (14%)
Query: 133 AKIAMEKLSGHQFENYSFKISYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQI 192
AKI + + +Y + P E+ P + A + D + P Q+R +
Sbjct: 43 AKIGGDAGTSLNSNDYGYGGQKRPLEDGDQPDAKKVAPQNDSFGTQL--PPMHQQQSRSV 100
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
VP VG IIG+ G I I +++ ++ I ++ G E+ + TPE
Sbjct: 101 -MTEEYKVPDGMVGFIIGRGGEQISRIQQESGCKIQI-APDSGGLPERSCMLTGTPESVQ 158
Query: 253 EACRMILEIMQKEADETKLAE-----EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTK 307
A R++ +I++K +I+ G +IGK G +K+++ G K
Sbjct: 159 SAKRLLDQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVK 218
Query: 308 ITISSLQDLSIYNPERT-----ITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGY 362
+ + +QD P+ T + + G A+ +++ +R+ G
Sbjct: 219 MVM--IQD----GPQNTGADKPLRITGDPYKVQQAKEMVLELIRD------------QGG 260
Query: 363 FSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAP 422
F + +++G E +++ IP AVG +IG+ G IK++ AG I+ P
Sbjct: 261 FREV--RNEYGS-----RIGGNEGIDVPIPRFAVGIVIGRNGEMIKKIQNDAGVRIQFKP 313
Query: 423 AEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNP--------------------K 462
+G ER+ ITGPP+ A I L+ NP
Sbjct: 314 DDG-TTPERIAQITGPPDRCQHAAEIITDLLRSVQAGNPGGPGPGGRGRGRGQGNWNMGP 372
Query: 463 EEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509
E + VP+ G +IGKGG+T+ + + A + + R+ P+
Sbjct: 373 PGGLQEFNFIVPTGKTGLIIGKGGETIKSISQQSGARIELQRNPPPN 419
Score = 75.5 bits (184), Expect = 1e-13
Identities = 68/272 (25%), Positives = 113/272 (41%), Gaps = 28/272 (10%)
Query: 180 GHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSR-VDIHRKENSGAA 238
G PG Q I++P G +IGK G TIK + ++ + V I + A
Sbjct: 180 GDGPGNAVQ--------EIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQDGPQNTGA 231
Query: 239 EKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGL--------VGRLI 290
+KP+ I P +A M+LE+++ + ++ E +I + G+ VG +I
Sbjct: 232 DKPLRITGDPYKVQQAKEMVLELIRDQGGFREVRNEYGSRIGGNEGIDVPIPRFAVGIVI 291
Query: 291 GKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFE 350
G+ G +KKI+++ G +I + PER + G + C A I LR
Sbjct: 292 GRNGEMIKKIQNDAGVRIQFKPDDGTT---PERIAQITGPPDRCQHAAEIITDLLRSVQA 348
Query: 351 NDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQL 410
+ + GP + N +PT G IIGK G IK +
Sbjct: 349 GNPGGPGPGGRGRGRGQGNWNMGPPGGLQEF------NFIVPTGKTGLIIGKGGETIKSI 402
Query: 411 ARFAGASIKIA--PAEGPDVSERMVIITGPPE 440
++ +GA I++ P D + ++ I G P+
Sbjct: 403 SQQSGARIELQRNPPPNADPNMKLFTIRGTPQ 434
Score = 71.2 bits (173), Expect = 2e-12
Identities = 45/152 (29%), Positives = 81/152 (53%), Gaps = 7/152 (4%)
Query: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIF 450
+P VG IIG+ G I ++ + +G I+IAP G + ER ++TG PE+ A+ R+
Sbjct: 107 VPDGMVGFIIGRGGEQISRIQQESGCKIQIAPDSG-GLPERSCMLTGTPESVQSAK-RLL 164
Query: 451 GKLKEEN-----FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRD 505
++ E+ F + I +P+S AG VIGKGG+T+ +LQ ++++ +D
Sbjct: 165 DQIVEKGRPAPGFHHGDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKMVMIQD 224
Query: 506 QTPDENEEVIVRIIGHFFASQTAQRKIREIVQ 537
+ + +RI G + Q A+ + E+++
Sbjct: 225 GPQNTGADKPLRITGDPYKVQQAKEMVLELIR 256
Score = 69.7 bits (169), Expect = 7e-12
Identities = 75/295 (25%), Positives = 128/295 (43%), Gaps = 55/295 (18%)
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M ++ + + EE + +G+VG +IG+ G + +I+ E+G KI I+ S P
Sbjct: 92 MHQQQSRSVMTEEYKVP----DGMVGFIIGRGGEQISRIQQESGCKIQIAPD---SGGLP 144
Query: 322 ERTITVKGTVEACASAEI---EIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHH 378
ER+ + GT E+ SA+ +I++K R A P HH
Sbjct: 145 ERSCMLTGTPESVQSAKRLLDQIVEKGRPA-------------------------PGFHH 179
Query: 379 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPD--VSERMVIIT 436
P + + IP G +IGK G IKQL AG + + +GP +++ + IT
Sbjct: 180 GDGPGNAVQEIMIPASKAGLVIGKGGETIKQLQERAGVKM-VMIQDGPQNTGADKPLRIT 238
Query: 437 GPPEAQFKAQGRIFGKLKEENFFNPKEEVKLE----------AHIRVPSSTAGRVIGKGG 486
G P +A+ + ++++ F EV+ E + +P G VIG+ G
Sbjct: 239 GDPYKVQQAKEMVLELIRDQGGF---REVRNEYGSRIGGNEGIDVPIPRFAVGIVIGRNG 295
Query: 487 KTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 540
+ + ++QN + P D T E I +I G Q A I ++++ V+
Sbjct: 296 EMIKKIQNDAGVRIQFKPDDGTTPER---IAQITGPPDRCQHAAEIITDLLRSVQ 347
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 15/108 (13%)
Query: 159 EVSSPSPPQRAQRGDHSSREQGH----APGGTSQARQIDFPLRILVPTQFVGAIIGKEGL 214
+ +P P RG R QG+ PGG + +VPT G IIGK G
Sbjct: 347 QAGNPGGPGPGGRG--RGRGQGNWNMGPPGGLQE-------FNFIVPTGKTGLIIGKGGE 397
Query: 215 TIKNITKQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260
TIK+I++Q+ +R+++ R N+ K TI TP+ A ++I E
Sbjct: 398 TIKSISQQSGARIELQRNPPPNADPNMKLFTIRGTPQQIDYARQLIEE 445
>gi|5902724 neuro-oncological ventral antigen 2 [Homo sapiens]
Length = 492
Score = 77.4 bits (189), Expect = 3e-14
Identities = 57/198 (28%), Positives = 93/198 (46%), Gaps = 13/198 (6%)
Query: 260 EIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIY 319
E++ + T E LK+L + G +IGK G+ + +++ ETG I +S +D
Sbjct: 18 EVVCTKRSNTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPG 77
Query: 320 NPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHH 379
ER V+GT EA + I +K+RE + T + L P P
Sbjct: 78 TTERVCLVQGTAEALNAVHSFIAEKVRE-----IPQAMTKPEVVNILQPQTTMNP----- 127
Query: 380 SYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGP 438
+ L +P G IIGK GA +K + +GA ++++ EG ++ ER+V ++G
Sbjct: 128 --DRAKQAKLIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPEGINLQERVVTVSGE 185
Query: 439 PEAQFKAQGRIFGKLKEE 456
PE KA I K++E+
Sbjct: 186 PEQVHKAVSAIVQKVQED 203
Score = 68.6 bits (166), Expect = 1e-11
Identities = 51/174 (29%), Positives = 86/174 (49%), Gaps = 19/174 (10%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEAQFK 444
+ + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ ++ G EA
Sbjct: 35 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEALNA 94
Query: 445 AQGRIFGKLKE----------ENFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGKTVN 490
I K++E N P+ + +A + VP+STAG +IGKGG TV
Sbjct: 95 VHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGATVK 154
Query: 491 ELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
+ + A V + + +E +V + G + + + IVQ+V++ Q
Sbjct: 155 AVMEQSGAWVQLSQKPEGINLQERVVTVSGE---PEQVHKAVSAIVQKVQEDPQ 205
Score = 58.5 bits (140), Expect = 2e-08
Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 18/172 (10%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEG 250
++ L++L+P+ G+IIGK G TI + K+T + + + + ++ G E+ + T E
Sbjct: 32 EYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLVQGTAEA 91
Query: 251 -------TSEACRMILEIMQKEADETKLAEEIPL--------KILAHNGLVGRLIGKEGR 295
+E R I + M K L + + K++ N G +IGK G
Sbjct: 92 LNAVHSFIAEKVREIPQAMTKPEVVNILQPQTTMNPDRAKQAKLIVPNSTAGLIIGKGGA 151
Query: 296 NLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
+K + ++G + +S + I ER +TV G E A I++K++E
Sbjct: 152 TVKAVMEQSGAWVQLSQKPE-GINLQERVVTVSGEPEQVHKAVSAIVQKVQE 202
Score = 42.7 bits (99), Expect = 9e-04
Identities = 38/115 (33%), Positives = 48/115 (41%), Gaps = 3/115 (2%)
Query: 437 GPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLT 496
GP A A G G L E E K I VP + G ++GKGGKT+ E Q LT
Sbjct: 379 GPLVAAAAAAGAAGGFLTAEKL--AAESAKELVEIAVPENLVGAILGKGGKTLVEYQELT 436
Query: 497 SAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQGV 550
A + I + + V I G A+Q AQ I + V + PQ V
Sbjct: 437 GARIQISKKGEFLPGTRNRRVTITGSPAATQAAQYLISQRVTYEQGVRASNPQKV 491
Score = 40.0 bits (92), Expect = 0.006
Identities = 24/65 (36%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
+E+V + +P VGAI+GK G + + GA I+I+ P R V ITG P A
Sbjct: 406 KELVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAA 465
Query: 442 QFKAQ 446
AQ
Sbjct: 466 TQAAQ 470
Score = 38.5 bits (88), Expect = 0.016
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 3/88 (3%)
Query: 460 NPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVR 517
N EE + + +PS AG +IGKGG+T+ +LQ T A + + +D P E V +
Sbjct: 26 NTGEEGEYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL- 84
Query: 518 IIGHFFASQTAQRKIREIVQQVKQQEQK 545
+ G A I E V+++ Q K
Sbjct: 85 VQGTAEALNAVHSFIAEKVREIPQAMTK 112
Score = 38.1 bits (87), Expect = 0.021
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253
+ I VP VGAI+GK G T+ + T +R+ I +K G + VTI +P T
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 254 ACRMI 258
A +I
Sbjct: 469 AQYLI 473
Score = 35.8 bits (81), Expect = 0.11
Identities = 23/81 (28%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336
++I LVG ++GK G+ L + + TG +I IS + R +T+ G+ A +
Sbjct: 409 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFLPGTRNRRVTITGSPAATQA 468
Query: 337 AEIEIMKKLREAFENDMLAVN 357
A+ I + R +E + A N
Sbjct: 469 AQYLISQ--RVTYEQGVRASN 487
>gi|56549651 neuro-oncological ventral antigen 1 isoform 2 [Homo
sapiens]
Length = 483
Score = 77.0 bits (188), Expect = 4e-14
Identities = 55/181 (30%), Positives = 90/181 (49%), Gaps = 13/181 (7%)
Query: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336
LK+L + G +IGK G+ + +++ ETG I +S +D ER ++GTVEA +
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 337 AEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAV 396
I +K+RE +N T S L P P + V + +P
Sbjct: 112 VHGFIAEKIREMPQN---VAKTEP--VSILQPQTTVNP-------DRIKQVKIIVPNSTA 159
Query: 397 GAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 455
G IIGK GA +K + +GA ++++ +G ++ ER+V ++G PE KA I K++E
Sbjct: 160 GLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKAVELIIQKIQE 219
Query: 456 E 456
+
Sbjct: 220 D 220
Score = 69.3 bits (168), Expect = 9e-12
Identities = 52/177 (29%), Positives = 88/177 (49%), Gaps = 19/177 (10%)
Query: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA
Sbjct: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Query: 442 QFKAQGRIFGKLKEE----------NFFNPKEEVK----LEAHIRVPSSTAGRVIGKGGK 487
G I K++E + P+ V + I VP+STAG +IGKGG
Sbjct: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNPDRIKQVKIIVPNSTAGLIIGKGGA 168
Query: 488 TVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
TV + + A V + + +E +V + G + ++ + I+Q++++ Q
Sbjct: 169 TVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE---PEQNRKAVELIIQKIQEDPQ 222
Score = 62.4 bits (150), Expect = 1e-09
Identities = 50/200 (25%), Positives = 87/200 (43%), Gaps = 19/200 (9%)
Query: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224
PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T
Sbjct: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
Query: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIMQKEADETKLAEEIPL----- 277
+ + + + ++ G E+ I T E + I E +++ E + +
Sbjct: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
Query: 278 ----------KILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327
KI+ N G +IGK G +K + ++G + +S D I ER +TV
Sbjct: 141 TVNPDRIKQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPD-GINLQERVVTV 199
Query: 328 KGTVEACASAEIEIMKKLRE 347
G E A I++K++E
Sbjct: 200 SGEPEQNRKAVELIIQKIQE 219
Score = 43.9 bits (102), Expect = 4e-04
Identities = 22/71 (30%), Positives = 42/71 (59%), Gaps = 1/71 (1%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENS-GAAEKPVTIHATPEGTSEA 254
++I+VP G IIGK G T+K + +Q+ + V + +K + E+ VT+ PE +A
Sbjct: 150 VKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGEPEQNRKA 209
Query: 255 CRMILEIMQKE 265
+I++ +Q++
Sbjct: 210 VELIIQKIQED 220
Score = 41.2 bits (95), Expect = 0.003
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)
Query: 405 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 464
A I+Q G I + P PD +R + PPEA G K N E+
Sbjct: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
Query: 465 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 522
+ + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G
Sbjct: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
Query: 523 FASQTAQ----RKIREIVQQVKQQE 543
A KIRE+ Q V + E
Sbjct: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253
+ I VP VGAI+GK G T+ + T +R+ I +K G + VTI TP T
Sbjct: 400 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 459
Query: 254 ACRMILE 260
A +I +
Sbjct: 460 AQYLITQ 466
Score = 39.7 bits (91), Expect = 0.007
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
+++V + +P VGAI+GK G + + GA I+I+ P R V ITG P A
Sbjct: 397 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 456
Query: 442 QFKAQGRIFGKLKEE 456
AQ I ++ E
Sbjct: 457 TQAAQYLITQRITYE 471
Score = 38.9 bits (89), Expect = 0.013
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 6/95 (6%)
Query: 263 QKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322
+K D +K EI + LVG ++GK G+ L + + TG +I IS +
Sbjct: 390 EKSTDGSKDVVEIAVP----ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 445
Query: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
R +T+ GT A +A+ I +++ +E + A N
Sbjct: 446 RKVTITGTPAATQAAQYLITQRI--TYEQGVRAAN 478
Score = 37.7 bits (86), Expect = 0.028
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 471 IRVPSSTAGRVIGKGGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQ 529
I VP + G ++GKGGKT+ E Q LT A + I + + V I G A+Q AQ
Sbjct: 402 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQ 461
Query: 530 RKIREIVQQVKQQEQKYPQGV 550
I + + + PQ V
Sbjct: 462 YLITQRITYEQGVRAANPQKV 482
>gi|194306631 poly(rC) binding protein 3 isoform 1 [Homo sapiens]
Length = 371
Score = 77.0 bits (188), Expect = 4e-14
Identities = 91/367 (24%), Positives = 153/367 (41%), Gaps = 76/367 (20%)
Query: 153 SYIPDEEVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKE 212
S +P +S+ S + Q G E + GG + + +R+L+ + VG+IIGK+
Sbjct: 11 SVLPHSTLSTLSHHPQPQFGRRM--ESKVSEGGLN----VTLTIRLLMHGKEVGSIIGKK 64
Query: 213 GLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMIL-----EIMQKEAD 267
G T+K + +++ +R++I E+ VTI + +A MI +I+ ++
Sbjct: 65 GETVKKMREESGARINI---SEGNCPERIVTITGPTDAIFKAFAMIAYKFEEDIINSMSN 121
Query: 268 ETKLAE-EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
++ + L+++ G LIGK G +K+I TG ++ ++ D+ + ER +T
Sbjct: 122 SPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQVAG--DMLPNSTERAVT 179
Query: 327 VKGTVEACASAEIEIMKKLREAFENDML-----------------AVNTHSGYFSSLYPH 369
+ GT +A +I + E+ T G ++ +P
Sbjct: 180 ISGTPDAIIQCVKQICVVMLESPPKGATIPYRPKPASTPVIFAGGQAYTIQGQYAIPHPD 239
Query: 370 -----HQFG----PFPH---------------HHSYPEQEIV---------------NLF 390
HQ PFP H S Q ++ L
Sbjct: 240 QLTKLHQLAMQQTPFPPLGQTNPAFPGEKLPLHSSEEAQNLMGQSSGLDASPPASTHELT 299
Query: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPA-EGPDVSERMVIITGPPEAQFKAQGRI 449
IP +G IIG++G I ++ + +GA IKIA A EG SER + ITG P AQ I
Sbjct: 300 IPNDLIGCIIGRQGTKINEIRQMSGAQIKIANATEGS--SERQITITGTPANISLAQYLI 357
Query: 450 FGKLKEE 456
+L E
Sbjct: 358 NARLTSE 364
Score = 76.3 bits (186), Expect = 7e-14
Identities = 49/134 (36%), Positives = 72/134 (53%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER+V ITGP +A FKA
Sbjct: 48 IRLLMHGKEVGSIIGKKGETVKKMREESGARINISEGNCP---ERIVTITGPTDAIFKAF 104
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I K +E+ + N K +R VP+S G +IGKGG + E++ T A+V
Sbjct: 105 AMIAYKFEEDIINSMSNSPATSKPPVTLRLVVPASQCGSLIGKGGSKIKEIRESTGAQVQ 164
Query: 502 VPRDQTPDENEEVI 515
V D P+ E +
Sbjct: 165 VAGDMLPNSTERAV 178
>gi|222352151 poly(rC) binding protein 1 [Homo sapiens]
Length = 356
Score = 76.3 bits (186), Expect = 7e-14
Identities = 54/168 (32%), Positives = 86/168 (51%), Gaps = 12/168 (7%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ +TGP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNCP---ERIITLTGPTNAIFKAF 72
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I KL+E+ + N + +R VP++ G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 502 VPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQG 549
V D P+ E I I G Q+ +++I + + + PQG
Sbjct: 133 VAGDMLPNSTERAIT-IAG---VPQSVTECVKQICLVMLETLSQSPQG 176
Score = 72.4 bits (176), Expect = 1e-12
Identities = 62/226 (27%), Positives = 102/226 (45%), Gaps = 28/226 (12%)
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M E+ L + +++L H VG +IGK+G ++K+I E+G +I IS P
Sbjct: 1 MDAGVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINISEGNC-----P 55
Query: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSY 381
ER IT+ G A A I+ KL E + M T+S S
Sbjct: 56 ERIITLTGPTNAIFKAFAMIIDKLEEDINSSM----TNSTAASR---------------- 95
Query: 382 PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
+ L +P G++IGK G IK++ GA +++A P+ +ER + I G P++
Sbjct: 96 -PPVTLRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQS 154
Query: 442 QFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 487
+ +I + E +P+ V + +P+S+ VI GG+
Sbjct: 155 VTECVKQICLVMLETLSQSPQGRVMTIPYQPMPASSP--VICAGGQ 198
Score = 60.5 bits (145), Expect = 4e-09
Identities = 68/275 (24%), Positives = 117/275 (42%), Gaps = 38/275 (13%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ +E
Sbjct: 100 LRLVVPATQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGVPQSVTECV 159
Query: 256 RMILEIMQKEADETKLAE--EIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
+ I +M + ++ IP + + + V G++ + G L
Sbjct: 160 KQICLVMLETLSQSPQGRVMTIPYQPMPASSPVICAGGQD-----RCSDAAGYPHATHDL 214
Query: 314 QDLSIYNPERTITVKG--TVEACASAEIEIMKKLREAFE-----NDMLAVNTHS----GY 362
+ P +++G T+ A++ + + + F +++ S GY
Sbjct: 215 EG----PPLDAYSIQGQHTISPLDLAKLNQVARQQSHFAMMHGGTGFAGIDSSSPEVKGY 270
Query: 363 FSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA- 421
++SL Q L IP +G IIG++GA+I ++ + +GA IKIA
Sbjct: 271 WASL-------------DASTQTTHELTIPNNLIGCIIGRQGANINEIRQMSGAQIKIAN 317
Query: 422 PAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 456
P EG S R V ITG + AQ I +L E
Sbjct: 318 PVEGS--SGRQVTITGSAASISLAQYLINARLSSE 350
Score = 58.5 bits (140), Expect = 2e-08
Identities = 37/156 (23%), Positives = 79/156 (50%), Gaps = 11/156 (7%)
Query: 184 GGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVT 243
G T + +R+L+ + VG+IIGK+G ++K I +++ +R++I E+ +T
Sbjct: 4 GVTESGLNVTLTIRLLMHGKEVGSIIGKKGESVKRIREESGARINI---SEGNCPERIIT 60
Query: 244 IHATPEGTSEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNL 297
+ +A MI++ ++++ + + + L+++ G LIGK G +
Sbjct: 61 LTGPTNAIFKAFAMIIDKLEEDINSSMTNSTAASRPPVTLRLVVPATQCGSLIGKGGCKI 120
Query: 298 KKIEHETGTKITISSLQDLSIYNPERTITVKGTVEA 333
K+I TG ++ ++ D+ + ER IT+ G ++
Sbjct: 121 KEIRESTGAQVQVAG--DMLPNSTERAITIAGVPQS 154
>gi|154355000 KH-type splicing regulatory protein [Homo sapiens]
Length = 711
Score = 75.5 bits (184), Expect = 1e-13
Identities = 88/391 (22%), Positives = 154/391 (39%), Gaps = 75/391 (19%)
Query: 158 EEVSSPSPPQRAQRGDHSSREQG--HAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLT 215
E+ P + A +GD S + G H P TS + VP VG IIG+ G
Sbjct: 113 EDGDQPESKKLASQGDSISSQLGPIHPPPRTSMTEEYR------VPDGMVGLIIGRGGEQ 166
Query: 216 IKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEA--------D 267
I I + + +V I ++ G E+ V++ PE +A M+ +I+ + D
Sbjct: 167 INKIQQDSGCKVQIS-PDSGGLPERSVSLTGAPESVQKAKMMLDDIVSRGRGGPPGQFHD 225
Query: 268 ETKLAEEIPLK-ILAHNGLVGRLIGKEGRNLKKIEHETGTKITI--SSLQDLSIYNPERT 324
+ ++ I+ G G +IGK G +K+++ G K+ + Q+ ++ P R
Sbjct: 226 NANGGQNGTVQEIMIPAGKAGLVIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRI 285
Query: 325 ITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQ 384
I V+ ++I++ E D + Y S +
Sbjct: 286 IGDPYKVQQACEMVMDILR------ERDQGGFGDRNEYGSRIGGG--------------- 324
Query: 385 EIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFK 444
+++ +P +VG +IG+ G IK++ AG I+ +G E++ I GPP+ + +
Sbjct: 325 --IDVPVPRHSVGVVIGRSGEMIKKIQNDAGVRIQFKQDDGTG-PEKIAHIMGPPD-RCE 380
Query: 445 AQGRIFGKLKEE--------------------------NFFNPKEEVKLEAHIRVPSSTA 478
RI L + N+ P E+ +P+
Sbjct: 381 HAARIINDLLQSLRSGPPGPPGGPGMPPGGRGRGRGQGNWGPPGGEMTFS----IPTHKC 436
Query: 479 GRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509
G VIG+GG+ V + T A V + R P+
Sbjct: 437 GLVIGRGGENVKAINQQTGAFVEISRQLPPN 467
Score = 71.2 bits (173), Expect = 2e-12
Identities = 52/181 (28%), Positives = 90/181 (49%), Gaps = 15/181 (8%)
Query: 371 QFGPFPHHHSYPEQEIVNLF-IPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVS 429
Q GP H P + + +P VG IIG+ G I ++ + +G ++I+P G +
Sbjct: 133 QLGPI---HPPPRTSMTEEYRVPDGMVGLIIGRGGEQINKIQQDSGCKVQISPDSG-GLP 188
Query: 430 ERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAH---------IRVPSSTAGR 480
ER V +TG PE+ KA+ + + P + A+ I +P+ AG
Sbjct: 189 ERSVSLTGAPESVQKAK-MMLDDIVSRGRGGPPGQFHDNANGGQNGTVQEIMIPAGKAGL 247
Query: 481 VIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQVK 540
VIGKGG+T+ +LQ ++I+ +D + + N + +RIIG + Q A + +I+++
Sbjct: 248 VIGKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQQACEMVMDILRERD 307
Query: 541 Q 541
Q
Sbjct: 308 Q 308
Score = 63.9 bits (154), Expect = 4e-10
Identities = 71/277 (25%), Positives = 123/277 (44%), Gaps = 36/277 (12%)
Query: 283 NGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIM 342
+G+VG +IG+ G + KI+ ++G K+ IS S PER++++ G E+ A++ +
Sbjct: 153 DGMVGLIIGRGGEQINKIQQDSGCKVQIS---PDSGGLPERSVSLTGAPESVQKAKMML- 208
Query: 343 KKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQE--IVNLFIPTQAVGAII 400
D + G P QF H ++ Q + + IP G +I
Sbjct: 209 ---------DDIVSRGRGG------PPGQF----HDNANGGQNGTVQEIMIPAGKAGLVI 249
Query: 401 GKKGAHIKQLARFAGASIKIAP--AEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE--E 456
GK G IKQL AG + + ++ +V + + II P + Q +A + L+E +
Sbjct: 250 GKGGETIKQLQERAGVKMILIQDGSQNTNVDKPLRIIGDPYKVQ-QACEMVMDILRERDQ 308
Query: 457 NFFNPKEE----VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENE 512
F + E + + VP + G VIG+ G+ + ++QN A V + Q
Sbjct: 309 GGFGDRNEYGSRIGGGIDVPVPRHSVGVVIGRSGEMIKKIQN--DAGVRIQFKQDDGTGP 366
Query: 513 EVIVRIIGHFFASQTAQRKIREIVQQVKQQEQKYPQG 549
E I I+G + A R I +++Q ++ P G
Sbjct: 367 EKIAHIMGPPDRCEHAARIINDLLQSLRSGPPGPPGG 403
Score = 33.1 bits (74), Expect = 0.69
Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 13/102 (12%)
Query: 163 PSPPQRAQRGDHSSREQGH--APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNIT 220
P P G R QG+ PGG + +PT G +IG+ G +K I
Sbjct: 401 PGGPGMPPGGRGRGRGQGNWGPPGGE---------MTFSIPTHKCGLVIGRGGENVKAIN 451
Query: 221 KQTQSRVDIHRK--ENSGAAEKPVTIHATPEGTSEACRMILE 260
+QT + V+I R+ N K I +P+ A ++I E
Sbjct: 452 QQTGAFVEISRQLPPNGDPNFKLFIIRGSPQQIDHAKQLIEE 493
>gi|56549653 neuro-oncological ventral antigen 1 isoform 1 [Homo
sapiens]
Length = 507
Score = 73.9 bits (180), Expect = 4e-13
Identities = 56/198 (28%), Positives = 91/198 (45%), Gaps = 23/198 (11%)
Query: 277 LKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACAS 336
LK+L + G +IGK G+ + +++ ETG I +S +D ER ++GTVEA +
Sbjct: 52 LKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEALNA 111
Query: 337 AEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEI---------- 386
I +K+RE +N T S L P P + P
Sbjct: 112 VHGFIAEKIREMPQN---VAKTEP--VSILQPQTTVNPDRIKQTLPSSPTTTKSSPSDPM 166
Query: 387 -------VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGP 438
V + +P G IIGK GA +K + +GA ++++ +G ++ ER+V ++G
Sbjct: 167 TTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE 226
Query: 439 PEAQFKAQGRIFGKLKEE 456
PE KA I K++E+
Sbjct: 227 PEQNRKAVELIIQKIQED 244
Score = 60.1 bits (144), Expect = 5e-09
Identities = 53/202 (26%), Positives = 90/202 (44%), Gaps = 45/202 (22%)
Query: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
Q + + IP+ A G+IIGK G I QL + GA+IK++ ++ P +ER+ +I G EA
Sbjct: 49 QYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCLIQGTVEA 108
Query: 442 QFKAQGRIFGKLKE----------------ENFFNPKEEVKL------------------ 467
G I K++E + NP + +K
Sbjct: 109 LNAVHGFIAEKIREMPQNVAKTEPVSILQPQTTVNP-DRIKQTLPSSPTTTKSSPSDPMT 167
Query: 468 -----EAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHF 522
+ I VP+STAG +IGKGG TV + + A V + + +E +V + G
Sbjct: 168 TSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERVVTVSGE- 226
Query: 523 FASQTAQRKIREIVQQVKQQEQ 544
+ ++ + I+Q++++ Q
Sbjct: 227 --PEQNRKAVELIIQKIQEDPQ 246
Score = 53.5 bits (127), Expect = 5e-07
Identities = 51/224 (22%), Positives = 90/224 (40%), Gaps = 43/224 (19%)
Query: 165 PPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQ 224
PP +R + E G T+ + L++L+P+ G+IIGK G TI + K+T
Sbjct: 22 PPDSRKRPLEAPPEAGSTKR-TNTGEDGQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETG 80
Query: 225 SRVDIHRKEN--SGAAEKPVTIHATPEGTSEACRMILEIM------------------QK 264
+ + + + ++ G E+ I T E + I E + Q
Sbjct: 81 ATIKLSKSKDFYPGTTERVCLIQGTVEALNAVHGFIAEKIREMPQNVAKTEPVSILQPQT 140
Query: 265 EADETKLAEEIP---------------------LKILAHNGLVGRLIGKEGRNLKKIEHE 303
+ ++ + +P +KI+ N G +IGK G +K + +
Sbjct: 141 TVNPDRIKQTLPSSPTTTKSSPSDPMTTSRANQVKIIVPNSTAGLIIGKGGATVKAVMEQ 200
Query: 304 TGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
+G + +S D I ER +TV G E A I++K++E
Sbjct: 201 SGAWVQLSQKPD-GINLQERVVTVSGEPEQNRKAVELIIQKIQE 243
Score = 47.0 bits (110), Expect = 5e-05
Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 5/84 (5%)
Query: 183 PGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRK-ENSGAAEKP 241
P TS+A Q+ +I+VP G IIGK G T+K + +Q+ + V + +K + E+
Sbjct: 165 PMTTSRANQV----KIIVPNSTAGLIIGKGGATVKAVMEQSGAWVQLSQKPDGINLQERV 220
Query: 242 VTIHATPEGTSEACRMILEIMQKE 265
VT+ PE +A +I++ +Q++
Sbjct: 221 VTVSGEPEQNRKAVELIIQKIQED 244
Score = 41.2 bits (95), Expect = 0.003
Identities = 45/145 (31%), Positives = 63/145 (43%), Gaps = 24/145 (16%)
Query: 405 AHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFFNPKEE 464
A I+Q G I + P PD +R + PPEA G K N E+
Sbjct: 5 APIQQNGTHTGVPIDLDP---PDSRKRP--LEAPPEA---------GSTKRTN---TGED 47
Query: 465 VKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV--PRDQTPDENEEVIVRIIGHF 522
+ + +PS AG +IGKGG+T+ +LQ T A + + +D P E V + I G
Sbjct: 48 GQYFLKVLIPSYAAGSIIGKGGQTIVQLQKETGATIKLSKSKDFYPGTTERVCL-IQGTV 106
Query: 523 FASQTAQ----RKIREIVQQVKQQE 543
A KIRE+ Q V + E
Sbjct: 107 EALNAVHGFIAEKIREMPQNVAKTE 131
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 2/67 (2%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKEN--SGAAEKPVTIHATPEGTSE 253
+ I VP VGAI+GK G T+ + T +R+ I +K G + VTI TP T
Sbjct: 424 VEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQA 483
Query: 254 ACRMILE 260
A +I +
Sbjct: 484 AQYLITQ 490
Score = 39.7 bits (91), Expect = 0.007
Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%)
Query: 384 QEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEG--PDVSERMVIITGPPEA 441
+++V + +P VGAI+GK G + + GA I+I+ P R V ITG P A
Sbjct: 421 KDVVEIAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAA 480
Query: 442 QFKAQGRIFGKLKEE 456
AQ I ++ E
Sbjct: 481 TQAAQYLITQRITYE 495
Score = 38.9 bits (89), Expect = 0.013
Identities = 27/95 (28%), Positives = 46/95 (48%), Gaps = 6/95 (6%)
Query: 263 QKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPE 322
+K D +K EI + LVG ++GK G+ L + + TG +I IS +
Sbjct: 414 EKSTDGSKDVVEIAVP----ENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRN 469
Query: 323 RTITVKGTVEACASAEIEIMKKLREAFENDMLAVN 357
R +T+ GT A +A+ I +++ +E + A N
Sbjct: 470 RKVTITGTPAATQAAQYLITQRI--TYEQGVRAAN 502
Score = 37.7 bits (86), Expect = 0.028
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 1/81 (1%)
Query: 471 IRVPSSTAGRVIGKGGKTVNELQNLTSAEV-IVPRDQTPDENEEVIVRIIGHFFASQTAQ 529
I VP + G ++GKGGKT+ E Q LT A + I + + V I G A+Q AQ
Sbjct: 426 IAVPENLVGAILGKGGKTLVEYQELTGARIQISKKGEFVPGTRNRKVTITGTPAATQAAQ 485
Query: 530 RKIREIVQQVKQQEQKYPQGV 550
I + + + PQ V
Sbjct: 486 YLITQRITYEQGVRAANPQKV 506
>gi|193083114 poly(rC) binding protein 2 isoform g [Homo sapiens]
Length = 318
Score = 73.9 bits (180), Expect = 4e-13
Identities = 73/307 (23%), Positives = 134/307 (43%), Gaps = 49/307 (15%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDML----------- 354
++ ++ D+ + ER IT+ G ++ +I + E+ +
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSP 186
Query: 355 ------AVNTHSGYFSSLYPH----HQF----GPFPHHH----------SYPEQEIVNLF 390
T G ++ P HQ FP H + + L
Sbjct: 187 VIFAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSAGLDASAQTTSHELT 246
Query: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQGRI 449
IP +G IIG++GA I ++ + +GA IKIA P EG ++R V ITG + AQ I
Sbjct: 247 IPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQYLI 304
Query: 450 FGKLKEE 456
+L E
Sbjct: 305 NVRLSSE 311
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 502 VPRDQTPDENEEVI 515
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
>gi|193083112 poly(rC) binding protein 2 isoform f [Homo sapiens]
Length = 335
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 502 VPRDQTPDENEEVI 515
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 70.9 bits (172), Expect = 3e-12
Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 29/213 (13%)
Query: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
Query: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
A I+ KL E + M T+S S + L +P
Sbjct: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
Query: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLK 454
G++IGK G IK++ GA +++A P+ +ER + I G P++ + +I +
Sbjct: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVML 167
Query: 455 EENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 487
E +P + V + P ++ VI GG+
Sbjct: 168 ETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/160 (23%), Positives = 82/160 (51%), Gaps = 15/160 (9%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKL 345
++ ++ D+ + ER IT+ G ++ IE +K++
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQI 162
Score = 45.1 bits (105), Expect = 2e-04
Identities = 29/69 (42%), Positives = 40/69 (57%), Gaps = 3/69 (4%)
Query: 389 LFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQG 447
L IP +G IIG++GA I ++ + +GA IKIA P EG ++R V ITG + AQ
Sbjct: 262 LTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITGSAASISLAQY 319
Query: 448 RIFGKLKEE 456
I +L E
Sbjct: 320 LINVRLSSE 328
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/67 (31%), Positives = 35/67 (52%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ E
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
Query: 256 RMILEIM 262
+ I +M
Sbjct: 160 KQICVVM 166
Score = 31.2 bits (69), Expect = 2.6
Identities = 17/63 (26%), Positives = 36/63 (57%), Gaps = 3/63 (4%)
Query: 283 NGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIM 342
N L+G +IG++G + +I +G +I I++ + S +R +T+ G+ + + A+ I
Sbjct: 266 NDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS---TDRQVTITGSAASISLAQYLIN 322
Query: 343 KKL 345
+L
Sbjct: 323 VRL 325
>gi|193083110 poly(rC) binding protein 2 isoform e [Homo sapiens]
Length = 361
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 502 VPRDQTPDENEEVI 515
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 68.9 bits (167), Expect = 1e-11
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 26/167 (15%)
Query: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
Query: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
A I+ KL E + M T+S S + L +P
Sbjct: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
Query: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
G++IGK G IK++ GA +++A P+ +ER + I G P++
Sbjct: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Score = 59.3 bits (142), Expect = 9e-09
Identities = 68/272 (25%), Positives = 113/272 (41%), Gaps = 28/272 (10%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ E
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
Query: 256 RMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKE----GRNLKKIEHETGTKITIS 311
+ I +M + + IP + + V G++ G + H T +
Sbjct: 160 KQICVVMLESPPK---GVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP 216
Query: 312 SLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQ 371
L+ P T++G A + ++ K + A + + + FS +
Sbjct: 217 DLEG----PPLEAYTIQGQY---AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSS- 268
Query: 372 FGPFPHHHSY------PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAE 424
P Y + L IP +G IIG++GA I ++ + +GA IKIA P E
Sbjct: 269 ----PEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVE 324
Query: 425 GPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 456
G ++R V ITG + AQ I +L E
Sbjct: 325 GS--TDRQVTITGSAASISLAQYLINVRLSSE 354
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/160 (23%), Positives = 82/160 (51%), Gaps = 15/160 (9%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKL 345
++ ++ D+ + ER IT+ G ++ IE +K++
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQI 162
>gi|193083108 poly(rC) binding protein 2 isoform d [Homo sapiens]
Length = 365
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 502 VPRDQTPDENEEVI 515
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 70.9 bits (172), Expect = 3e-12
Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 29/213 (13%)
Query: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
Query: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
A I+ KL E + M T+S S + L +P
Sbjct: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
Query: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLK 454
G++IGK G IK++ GA +++A P+ +ER + I G P++ + +I +
Sbjct: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVML 167
Query: 455 EENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 487
E +P + V + P ++ VI GG+
Sbjct: 168 ETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
Score = 59.7 bits (143), Expect = 7e-09
Identities = 68/273 (24%), Positives = 114/273 (41%), Gaps = 26/273 (9%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ E
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
Query: 256 RMILEIMQKEADETK-LAEEIPLKILAHNGLVGRLIGKE----GRNLKKIEHETGTKITI 310
+ I +M + ++ IP + + V G++ G + H T +
Sbjct: 160 KQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLN 219
Query: 311 SSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHH 370
L+ P T++G A + ++ K + A + + + FS +
Sbjct: 220 PDLEG----PPLEAYTIQGQY---AIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSS 272
Query: 371 QFGPFPHHHSY------PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PA 423
P Y + L IP +G IIG++GA I ++ + +GA IKIA P
Sbjct: 273 -----PEVKGYWGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPV 327
Query: 424 EGPDVSERMVIITGPPEAQFKAQGRIFGKLKEE 456
EG ++R V ITG + AQ I +L E
Sbjct: 328 EGS--TDRQVTITGSAASISLAQYLINVRLSSE 358
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/160 (23%), Positives = 82/160 (51%), Gaps = 15/160 (9%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKL 345
++ ++ D+ + ER IT+ G ++ IE +K++
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQI 162
>gi|14141166 poly(rC) binding protein 2 isoform b [Homo sapiens]
Length = 362
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 502 VPRDQTPDENEEVI 515
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 68.9 bits (167), Expect = 1e-11
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 26/167 (15%)
Query: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
Query: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
A I+ KL E + M T+S S + L +P
Sbjct: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
Query: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
G++IGK G IK++ GA +++A P+ +ER + I G P++
Sbjct: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Score = 61.2 bits (147), Expect = 2e-09
Identities = 67/266 (25%), Positives = 111/266 (41%), Gaps = 15/266 (5%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ E
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
Query: 256 RMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKE----GRNLKKIEHETGTKITIS 311
+ I +M + + IP + + V G++ G + H T +
Sbjct: 160 KQICVVMLESPPK---GVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLNP 216
Query: 312 SLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQ 371
L+ P T++G ++ + + M NT S P +
Sbjct: 217 DLEG----PPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVK 272
Query: 372 FGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSE 430
G + + + L IP +G IIG++GA I ++ + +GA IKIA P EG ++
Sbjct: 273 -GYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TD 329
Query: 431 RMVIITGPPEAQFKAQGRIFGKLKEE 456
R V ITG + AQ I +L E
Sbjct: 330 RQVTITGSAASISLAQYLINVRLSSE 355
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/160 (23%), Positives = 82/160 (51%), Gaps = 15/160 (9%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKL 345
++ ++ D+ + ER IT+ G ++ IE +K++
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQI 162
>gi|14141168 poly(rC) binding protein 2 isoform a [Homo sapiens]
Length = 366
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 502 VPRDQTPDENEEVI 515
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 70.9 bits (172), Expect = 3e-12
Identities = 58/213 (27%), Positives = 96/213 (45%), Gaps = 29/213 (13%)
Query: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
Query: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
A I+ KL E + M T+S S + L +P
Sbjct: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
Query: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLK 454
G++IGK G IK++ GA +++A P+ +ER + I G P++ + +I +
Sbjct: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVML 167
Query: 455 EENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGK 487
E +P + V + P ++ VI GG+
Sbjct: 168 ETLSQSPPKGVTIPYR---PKPSSSPVIFAGGQ 197
Score = 61.6 bits (148), Expect = 2e-09
Identities = 67/267 (25%), Positives = 112/267 (41%), Gaps = 13/267 (4%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
LR++VP G++IGK G IK I + T ++V + + E+ +TI P+ E
Sbjct: 100 LRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQSIIECV 159
Query: 256 RMILEIMQKEADETK-LAEEIPLKILAHNGLVGRLIGKE----GRNLKKIEHETGTKITI 310
+ I +M + ++ IP + + V G++ G + H T +
Sbjct: 160 KQICVVMLETLSQSPPKGVTIPYRPKPSSSPVIFAGGQDRYSTGSDSASFPHTTPSMCLN 219
Query: 311 SSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHH 370
L+ P T++G ++ + + M NT S P
Sbjct: 220 PDLEG----PPLEAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEV 275
Query: 371 QFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVS 429
+ G + + + L IP +G IIG++GA I ++ + +GA IKIA P EG +
Sbjct: 276 K-GYWAGLDASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--T 332
Query: 430 ERMVIITGPPEAQFKAQGRIFGKLKEE 456
+R V ITG + AQ I +L E
Sbjct: 333 DRQVTITGSAASISLAQYLINVRLSSE 359
Score = 55.5 bits (132), Expect = 1e-07
Identities = 37/160 (23%), Positives = 82/160 (51%), Gaps = 15/160 (9%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKL------AEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETG 305
+A MI++ ++++ + + L+++ G LIGK G +K+I TG
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 306 TKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKL 345
++ ++ D+ + ER IT+ G ++ IE +K++
Sbjct: 129 AQVQVAG--DMLPNSTERAITIAGIPQSI----IECVKQI 162
>gi|148833484 poly(rC) binding protein 2 isoform c [Homo sapiens]
Length = 331
Score = 73.9 bits (180), Expect = 4e-13
Identities = 47/134 (35%), Positives = 71/134 (52%), Gaps = 8/134 (5%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L + + VG+IIGKKG +K++ +GA I I+ P ER++ + GP A FKA
Sbjct: 16 IRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNCP---ERIITLAGPTNAIFKAF 72
Query: 447 GRIFGKLKEE---NFFNPKEEVKLEAHIR--VPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
I KL+E+ + N + +R VP+S G +IGKGG + E++ T A+V
Sbjct: 73 AMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTGAQVQ 132
Query: 502 VPRDQTPDENEEVI 515
V D P+ E I
Sbjct: 133 VAGDMLPNSTERAI 146
Score = 68.9 bits (167), Expect = 1e-11
Identities = 49/167 (29%), Positives = 78/167 (46%), Gaps = 26/167 (15%)
Query: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
+ +++L H VG +IGK+G ++KK+ E+G +I IS PER IT+ G A
Sbjct: 14 LTIRLLMHGKEVGSIIGKKGESVKKMREESGARINISEGNC-----PERIITLAGPTNAI 68
Query: 335 ASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQ 394
A I+ KL E + M T+S S + L +P
Sbjct: 69 FKAFAMIIDKLEEDISSSM----TNSTAASR-----------------PPVTLRLVVPAS 107
Query: 395 AVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
G++IGK G IK++ GA +++A P+ +ER + I G P++
Sbjct: 108 QCGSLIGKGGCKIKEIRESTGAQVQVAGDMLPNSTERAITIAGIPQS 154
Score = 56.6 bits (135), Expect = 6e-08
Identities = 70/319 (21%), Positives = 134/319 (42%), Gaps = 60/319 (18%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
+ +R+L+ + VG+IIGK+G ++K + +++ +R++I E+ +T+
Sbjct: 12 VTLTIRLLMHGKEVGSIIGKKGESVKKMREESGARINI---SEGNCPERIITLAGPTNAI 68
Query: 252 SEACRMILEIMQKEADETKLAEE------IPLKILAHNGLVGRLIGKEGRNLKK------ 299
+A MI++ ++++ + + L+++ G LIGK G +K+
Sbjct: 69 FKAFAMIIDKLEEDISSSMTNSTAASRPPVTLRLVVPASQCGSLIGKGGCKIKEIRESTG 128
Query: 300 ---------IEHETGTKITISSLQD-----------LSIYNPERTITVKGTVEACASAEI 339
+ + T ITI+ + + + +P + +T+ + +S I
Sbjct: 129 AQVQVAGDMLPNSTERAITIAGIPQSIIECVKQICVVMLESPPKGVTIPYRPKPSSSPVI 188
Query: 340 ------------------EIMKKLREAFEND---MLAVNTHSGYFSSLYPHHQFGPFPHH 378
++ K + A + M NT S P + G +
Sbjct: 189 FAGGQAYTIQGQYAIPQPDLTKLHQLAMQQSHFPMTHGNTGFSGIESSSPEVK-GYWAGL 247
Query: 379 HSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITG 437
+ + L IP +G IIG++GA I ++ + +GA IKIA P EG ++R V ITG
Sbjct: 248 DASAQTTSHELTIPNDLIGCIIGRQGAKINEIRQMSGAQIKIANPVEGS--TDRQVTITG 305
Query: 438 PPEAQFKAQGRIFGKLKEE 456
+ AQ I +L E
Sbjct: 306 SAASISLAQYLINVRLSSE 324
>gi|14670373 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 72.8 bits (177), Expect = 8e-13
Identities = 76/298 (25%), Positives = 130/298 (43%), Gaps = 54/298 (18%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
I LR+L+ + VG+IIGK+G T+K I +Q+ +R+ I + G+ + +T T G+
Sbjct: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSCPERIT---TITGS 68
Query: 252 SEACRMILEIMQKEADETKLA----------EEIPLKILAHNGLVGRLIGKEGRNLKKIE 301
+ A + ++ + DE A + L+++ G LIGK G +K+I
Sbjct: 69 TAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIR 128
Query: 302 HETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE-------------- 347
TG ++ ++ DL + ER +TV G +A +I + E
Sbjct: 129 ETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSL 186
Query: 348 AFENDMLAVN---THSGYFSSLYP---------HHQFGPFPHHHSYP------EQEIVNL 389
+ +L+ N + G + ++ P PF P +
Sbjct: 187 SLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEF 246
Query: 390 FIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQ 446
+P +G +IG++G+ I ++ + +GA IKI AEG ER V ITG P + AQ
Sbjct: 247 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEG--AGERHVTITGSPVSIALAQ 302
Score = 72.4 bits (176), Expect = 1e-12
Identities = 65/237 (27%), Positives = 105/237 (44%), Gaps = 36/237 (15%)
Query: 267 DETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
+E +L+ + L++L H VG +IGK+G +K+I ++ +ITIS PER T
Sbjct: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSC-----PERITT 64
Query: 327 VKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEI 386
+ G+ A A I KL E D+ A + G S
Sbjct: 65 ITGSTAAVFHAVSMIAFKLDE----DLCAAPANGGNVSR-----------------PPVT 103
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L IP G++IGK G IK++ GA +++A P+ +ER V ++G P+A
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCV 163
Query: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVI---GKGGKTVNELQNLTSAEV 500
+I + E +P + + H PS + G V+ +G + +T AEV
Sbjct: 164 RQICAVILE----SPPKGATIPYH---PSLSLGTVLLSANQGFSVQGQYGAVTPAEV 213
Score = 61.2 bits (147), Expect = 2e-09
Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 396 VGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 455
VG+IIGKKG +K++ + A I I+ P ER+ ITG A F A I KL E
Sbjct: 29 VGSIIGKKGETVKRIREQSSARITISEGSCP---ERITTITGSTAAVFHAVSMIAFKLDE 85
Query: 456 ENFFNPKE-----EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDE 510
+ P + + +P+S G +IGK G + E++ T A+V V D P+
Sbjct: 86 DLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNS 145
Query: 511 NEEVI 515
E +
Sbjct: 146 TERAV 150
Score = 43.5 bits (101), Expect = 5e-04
Identities = 49/226 (21%), Positives = 84/226 (37%), Gaps = 62/226 (27%)
Query: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKP 241
AP + LR+++P G++IGK G IK I + T ++V + + E+
Sbjct: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
Query: 242 VTIHATPEG----TSEACRMILEIMQK--------------------------------- 264
VT+ P+ + C +ILE K
Sbjct: 150 VTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVT 209
Query: 265 EADETKLAE----EIPL------------------KILAHNGLVGRLIGKEGRNLKKIEH 302
A+ TKL + +P + L N L+G +IG++G + +I
Sbjct: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQ 269
Query: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA 348
+G I I + + + ER +T+ G+ + A A+ I L A
Sbjct: 270 MSGAHIKIGNQAEGA---GERHVTITGSPVSIALAQYLITACLETA 312
Score = 30.8 bits (68), Expect = 3.4
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 451 GKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509
G L+EE P+ + L + + G +IGK G+TV ++ +SA + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
>gi|14670369 poly(rC) binding protein 4 isoform c [Homo sapiens]
Length = 403
Score = 72.8 bits (177), Expect = 8e-13
Identities = 76/298 (25%), Positives = 130/298 (43%), Gaps = 54/298 (18%)
Query: 192 IDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGT 251
I LR+L+ + VG+IIGK+G T+K I +Q+ +R+ I + G+ + +T T G+
Sbjct: 16 ITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITI----SEGSCPERIT---TITGS 68
Query: 252 SEACRMILEIMQKEADETKLA----------EEIPLKILAHNGLVGRLIGKEGRNLKKIE 301
+ A + ++ + DE A + L+++ G LIGK G +K+I
Sbjct: 69 TAAVFHAVSMIAFKLDEDLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIR 128
Query: 302 HETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE-------------- 347
TG ++ ++ DL + ER +TV G +A +I + E
Sbjct: 129 ETTGAQVQVAG--DLLPNSTERAVTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSL 186
Query: 348 AFENDMLAVN---THSGYFSSLYP---------HHQFGPFPHHHSYP------EQEIVNL 389
+ +L+ N + G + ++ P PF P +
Sbjct: 187 SLGTVLLSANQGFSVQGQYGAVTPAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEF 246
Query: 390 FIPTQAVGAIIGKKGAHIKQLARFAGASIKIA-PAEGPDVSERMVIITGPPEAQFKAQ 446
+P +G +IG++G+ I ++ + +GA IKI AEG ER V ITG P + AQ
Sbjct: 247 LVPNDLIGCVIGRQGSKISEIRQMSGAHIKIGNQAEG--AGERHVTITGSPVSIALAQ 302
Score = 72.4 bits (176), Expect = 1e-12
Identities = 65/237 (27%), Positives = 105/237 (44%), Gaps = 36/237 (15%)
Query: 267 DETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTIT 326
+E +L+ + L++L H VG +IGK+G +K+I ++ +ITIS PER T
Sbjct: 10 EEPELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSC-----PERITT 64
Query: 327 VKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEI 386
+ G+ A A I KL E D+ A + G S
Sbjct: 65 ITGSTAAVFHAVSMIAFKLDE----DLCAAPANGGNVSR-----------------PPVT 103
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ L IP G++IGK G IK++ GA +++A P+ +ER V ++G P+A
Sbjct: 104 LRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERAVTVSGVPDAIILCV 163
Query: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVI---GKGGKTVNELQNLTSAEV 500
+I + E +P + + H PS + G V+ +G + +T AEV
Sbjct: 164 RQICAVILE----SPPKGATIPYH---PSLSLGTVLLSANQGFSVQGQYGAVTPAEV 213
Score = 61.2 bits (147), Expect = 2e-09
Identities = 41/125 (32%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 396 VGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKE 455
VG+IIGKKG +K++ + A I I+ P ER+ ITG A F A I KL E
Sbjct: 29 VGSIIGKKGETVKRIREQSSARITISEGSCP---ERITTITGSTAAVFHAVSMIAFKLDE 85
Query: 456 ENFFNPKE-----EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDE 510
+ P + + +P+S G +IGK G + E++ T A+V V D P+
Sbjct: 86 DLCAAPANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNS 145
Query: 511 NEEVI 515
E +
Sbjct: 146 TERAV 150
Score = 43.5 bits (101), Expect = 5e-04
Identities = 49/226 (21%), Positives = 84/226 (37%), Gaps = 62/226 (27%)
Query: 182 APGGTSQARQIDFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKP 241
AP + LR+++P G++IGK G IK I + T ++V + + E+
Sbjct: 90 APANGGNVSRPPVTLRLVIPASQCGSLIGKAGTKIKEIRETTGAQVQVAGDLLPNSTERA 149
Query: 242 VTIHATPEG----TSEACRMILEIMQK--------------------------------- 264
VT+ P+ + C +ILE K
Sbjct: 150 VTVSGVPDAIILCVRQICAVILESPPKGATIPYHPSLSLGTVLLSANQGFSVQGQYGAVT 209
Query: 265 EADETKLAE----EIPL------------------KILAHNGLVGRLIGKEGRNLKKIEH 302
A+ TKL + +P + L N L+G +IG++G + +I
Sbjct: 210 PAEVTKLQQLSSHAVPFATPSVVPGLDPGTQTSSQEFLVPNDLIGCVIGRQGSKISEIRQ 269
Query: 303 ETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA 348
+G I I + + + ER +T+ G+ + A A+ I L A
Sbjct: 270 MSGAHIKIGNQAEGA---GERHVTITGSPVSIALAQYLITACLETA 312
Score = 30.8 bits (68), Expect = 3.4
Identities = 16/59 (27%), Positives = 29/59 (49%), Gaps = 4/59 (6%)
Query: 451 GKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPD 509
G L+EE P+ + L + + G +IGK G+TV ++ +SA + + P+
Sbjct: 6 GGLEEE----PELSITLTLRMLMHGKEVGSIIGKKGETVKRIREQSSARITISEGSCPE 60
>gi|4885409 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 68.6 bits (166), Expect = 1e-11
Identities = 87/398 (21%), Positives = 153/398 (38%), Gaps = 67/398 (16%)
Query: 146 ENYSFKISYIPDEEVSS----PSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVP 201
+ Y + PD E S+ PQ Q+ + RE R D +++
Sbjct: 463 DQYKVSVRIPPDSEKSNLIRIEGDPQGVQQ---AKRELLELASRMENERTKD----LIIE 515
Query: 202 TQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEI 261
+F IIG++G I+ I + ++ A + + P+ E C ++
Sbjct: 516 QRFHRTIIGQKGERIREIRDKFP---EVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQK 572
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M + E + +P+ H + IGK G N+KKI E+ TKI + + S
Sbjct: 573 MVADLVENSYSISVPIFKQFHKNI----IGKGGANIKKIREESNTKIDLPAENSNS---- 624
Query: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSY 381
TI + G C +A I+ + + D+ +
Sbjct: 625 -ETIIITGKRANCEAARSRIL-----SIQKDLANIAE----------------------- 655
Query: 382 PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
V + IP + ++IG KG I+ + G P EG V+I GP
Sbjct: 656 -----VEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGS--GSDTVVIRGPSSD 708
Query: 442 QFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
KA+ ++ +E K+ IR +IGKGG + ++++ T A VI
Sbjct: 709 VEKAKKQLLHLAEE------KQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVI 762
Query: 502 VPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQV 539
P + D++ ++ IIG A + AQ+++ ++Q +
Sbjct: 763 FPAAEDKDQD---LITIIGKEDAVREAQKELEALIQNL 797
Score = 55.1 bits (131), Expect = 2e-07
Identities = 82/388 (21%), Positives = 152/388 (39%), Gaps = 72/388 (18%)
Query: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRM 257
+ +P + +IGK G ++++ +T +++ I R ++ + I T EG +A
Sbjct: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS---NQIKITGTKEGIEKARHE 211
Query: 258 ILEIMQKEADETKLAEEIPLKILAHNGLVG---RLIGKEGRNLKKIEHETGTKITISSLQ 314
+L I ++ + + E + ++ H + G RL+G+ I ETGT+I I
Sbjct: 212 VLLISAEQ--DKRAVERLEVEKAFHPFIAGPYNRLVGE-------IMQETGTRINIPPP- 261
Query: 315 DLSIYNPERTITVKGTVEACASAEIEIMKKLREAFE----------------------ND 352
S+ E T G E A A I K E + N
Sbjct: 262 --SVNRTEIVFT--GEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
Query: 353 MLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQ---------------EIVNLFIPTQAVG 397
+ + +G + P PE+ + ++ P+
Sbjct: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHR 377
Query: 398 AIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEEN 457
IIGKKG ++ ++ + + I EG D + + GP E AQ +I G +K+
Sbjct: 378 FIIGKKGQNLAKITQQM-PKVHIEFTEGED----KITLEGPTEDVNVAQEQIEGMVKD-- 430
Query: 458 FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVR 517
N + V+ I + +IGK G +N +++ V +P PD + ++R
Sbjct: 431 LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP----PDSEKSNLIR 482
Query: 518 IIGHFFASQTAQRKIREIVQQVKQQEQK 545
I G Q A+R++ E+ +++ + K
Sbjct: 483 IEGDPQGVQQAKRELLELASRMENERTK 510
Score = 47.8 bits (112), Expect = 3e-05
Identities = 73/298 (24%), Positives = 106/298 (35%), Gaps = 79/298 (26%)
Query: 250 GTSEACRMILEIMQKEAD--ETKLAEEIPLKIL----------AHNGLVGRL-------- 289
G E ++ LEIMQ+ E LA++ L I+ A +V RL
Sbjct: 96 GEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATV 155
Query: 290 ----------IGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEI 339
IGK G L+ +E +T TKI I D P I + GT E A
Sbjct: 156 AIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD-----PSNQIKITGTKEGIEKARH 210
Query: 340 EIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAI 399
E+ L + E D AV L F PF I
Sbjct: 211 EV---LLISAEQDKRAV-------ERLEVEKAFHPF-----------------------I 237
Query: 400 IGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFF 459
G + ++ + G I I P P V+ ++ TG E +A RI + +
Sbjct: 238 AGPYNRLVGEIMQETGTRINIPP---PSVNRTEIVFTGEKEQLAQAVARI------KKIY 288
Query: 460 NPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVR 517
K++ + V S VIG G ++ E+ T V +P + +E VI+R
Sbjct: 289 EEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIP--PSDSISETVILR 344
Score = 42.7 bits (99), Expect = 9e-04
Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 14/171 (8%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
+ + +P + ++IG +G I++I ++ V IH G+ V I +A
Sbjct: 656 VEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVE-GSGSDTVVIRGPSSDVEKAK 713
Query: 256 RMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQD 315
+ +L + E K + + I A LIGK G ++K+ TG ++ + +D
Sbjct: 714 KQLLHLA-----EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAED 768
Query: 316 LSIYNPERTITVKGTVEACASAEIE---IMKKLREAFENDMLAVNTHSGYF 363
+ IT+ G +A A+ E +++ L E+ ML H +F
Sbjct: 769 ----KDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHF 815
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 188 QARQID-----FPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPV 242
QA Q D F L + V ++ IIG++G I I + + K++ + +
Sbjct: 1042 QAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQI 1101
Query: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
TI + T A IL I+ + E ++E++PL H R+IG G+ ++KI
Sbjct: 1102 TITGYEKNTEAARDAILRIVGEL--EQMVSEDVPLDHRVH----ARIIGARGKAIRKIMD 1155
Query: 303 E 303
E
Sbjct: 1156 E 1156
Score = 41.2 bits (95), Expect = 0.003
Identities = 69/340 (20%), Positives = 136/340 (40%), Gaps = 67/340 (19%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDI-HRKENSGAAEKPVTIHATPE----- 249
L +P +F +++G +G I+ IT+ ++ R+EN+ + +PV E
Sbjct: 876 LECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGR 935
Query: 250 -------GTSEACRMILEIMQKEADET-KLAEE----IPLKILAHNGLVGRLIGKEGRNL 297
G+ C +I+ +KE E K A E + +++ L +IG++G +
Sbjct: 936 EAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGI 995
Query: 298 KKI--EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA-FENDML 354
+K+ E E + LQ I + G A+ ++++++E E +
Sbjct: 996 RKMMDEFEVNIHVPAPELQS-------DIIAITGLAANLDRAKAGLLERVKELQAEQEDR 1048
Query: 355 AVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFA 414
A+ + +++ + + IIG+KGA I Q+
Sbjct: 1049 ALRSFK--------------------------LSVTVDPKYHPKIIGRKGAVITQIRLEH 1082
Query: 415 GASIKIAPAEGPDVSERMVIITG---PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHI 471
+I+ + + + + ITG EA A RI G+L++ E+V L+ +
Sbjct: 1083 DVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQM----VSEDVPLDHRV 1138
Query: 472 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN 511
R+IG GK + ++ + ++ P+ PD N
Sbjct: 1139 HA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1172
Score = 33.1 bits (74), Expect = 0.69
Identities = 59/288 (20%), Positives = 114/288 (39%), Gaps = 63/288 (21%)
Query: 208 IIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEAD 267
+IG +G +++ I ++T V+I S + + V + PE +A + E+ K
Sbjct: 310 VIGPKGNSLQEILERTGVSVEI---PPSDSISETVILRGEPEKLGQA---LTEVYAKANS 363
Query: 268 ETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327
T + + A + L +IGK+G+NL KI + K+ I + E IT+
Sbjct: 364 FTVSS------VAAPSWLHRFIIGKKGQNLAKITQQM-PKVHIEFTEG------EDKITL 410
Query: 328 KGTVEACASAEIEIMKKLREAFEN-DMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEI 386
+G E A+ +I +++ D + +N H+F H H
Sbjct: 411 EGPTEDVNVAQEQIEGMVKDLINRMDYVEINI----------DHKF----HRH------- 449
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+IGK GA+I ++ S++I P ++ I G P+ +A+
Sbjct: 450 ------------LIGKSGANINRIKDQYKVSVRIPP---DSEKSNLIRIEGDPQGVQQAK 494
Query: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQN 494
+ K+ + + R +IG+ G+ + E+++
Sbjct: 495 RELLELASRMENERTKDLIIEQRFHRT-------IIGQKGERIREIRD 535
>gi|42716280 high density lipoprotein binding protein [Homo sapiens]
Length = 1268
Score = 68.6 bits (166), Expect = 1e-11
Identities = 87/398 (21%), Positives = 153/398 (38%), Gaps = 67/398 (16%)
Query: 146 ENYSFKISYIPDEEVSS----PSPPQRAQRGDHSSREQGHAPGGTSQARQIDFPLRILVP 201
+ Y + PD E S+ PQ Q+ + RE R D +++
Sbjct: 463 DQYKVSVRIPPDSEKSNLIRIEGDPQGVQQ---AKRELLELASRMENERTKD----LIIE 515
Query: 202 TQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEI 261
+F IIG++G I+ I + ++ A + + P+ E C ++
Sbjct: 516 QRFHRTIIGQKGERIREIRDKFP---EVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQK 572
Query: 262 MQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNP 321
M + E + +P+ H + IGK G N+KKI E+ TKI + + S
Sbjct: 573 MVADLVENSYSISVPIFKQFHKNI----IGKGGANIKKIREESNTKIDLPAENSNS---- 624
Query: 322 ERTITVKGTVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSY 381
TI + G C +A I+ + + D+ +
Sbjct: 625 -ETIIITGKRANCEAARSRIL-----SIQKDLANIAE----------------------- 655
Query: 382 PEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEA 441
V + IP + ++IG KG I+ + G P EG V+I GP
Sbjct: 656 -----VEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGS--GSDTVVIRGPSSD 708
Query: 442 QFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVI 501
KA+ ++ +E K+ IR +IGKGG + ++++ T A VI
Sbjct: 709 VEKAKKQLLHLAEE------KQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVI 762
Query: 502 VPRDQTPDENEEVIVRIIGHFFASQTAQRKIREIVQQV 539
P + D++ ++ IIG A + AQ+++ ++Q +
Sbjct: 763 FPAAEDKDQD---LITIIGKEDAVREAQKELEALIQNL 797
Score = 55.1 bits (131), Expect = 2e-07
Identities = 82/388 (21%), Positives = 152/388 (39%), Gaps = 72/388 (18%)
Query: 198 ILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRM 257
+ +P + +IGK G ++++ +T +++ I R ++ + I T EG +A
Sbjct: 155 VAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPS---NQIKITGTKEGIEKARHE 211
Query: 258 ILEIMQKEADETKLAEEIPLKILAHNGLVG---RLIGKEGRNLKKIEHETGTKITISSLQ 314
+L I ++ + + E + ++ H + G RL+G+ I ETGT+I I
Sbjct: 212 VLLISAEQ--DKRAVERLEVEKAFHPFIAGPYNRLVGE-------IMQETGTRINIPPP- 261
Query: 315 DLSIYNPERTITVKGTVEACASAEIEIMKKLREAFE----------------------ND 352
S+ E T G E A A I K E + N
Sbjct: 262 --SVNRTEIVFT--GEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNS 317
Query: 353 MLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQ---------------EIVNLFIPTQAVG 397
+ + +G + P PE+ + ++ P+
Sbjct: 318 LQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHR 377
Query: 398 AIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEEN 457
IIGKKG ++ ++ + + I EG D + + GP E AQ +I G +K+
Sbjct: 378 FIIGKKGQNLAKITQQM-PKVHIEFTEGED----KITLEGPTEDVNVAQEQIEGMVKD-- 430
Query: 458 FFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVR 517
N + V+ I + +IGK G +N +++ V +P PD + ++R
Sbjct: 431 LINRMDYVE----INIDHKFHRHLIGKSGANINRIKDQYKVSVRIP----PDSEKSNLIR 482
Query: 518 IIGHFFASQTAQRKIREIVQQVKQQEQK 545
I G Q A+R++ E+ +++ + K
Sbjct: 483 IEGDPQGVQQAKRELLELASRMENERTK 510
Score = 47.8 bits (112), Expect = 3e-05
Identities = 73/298 (24%), Positives = 106/298 (35%), Gaps = 79/298 (26%)
Query: 250 GTSEACRMILEIMQKEAD--ETKLAEEIPLKIL----------AHNGLVGRL-------- 289
G E ++ LEIMQ+ E LA++ L I+ A +V RL
Sbjct: 96 GEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATV 155
Query: 290 ----------IGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEI 339
IGK G L+ +E +T TKI I D P I + GT E A
Sbjct: 156 AIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDD-----PSNQIKITGTKEGIEKARH 210
Query: 340 EIMKKLREAFENDMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAI 399
E+ L + E D AV L F PF I
Sbjct: 211 EV---LLISAEQDKRAV-------ERLEVEKAFHPF-----------------------I 237
Query: 400 IGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQGRIFGKLKEENFF 459
G + ++ + G I I P P V+ ++ TG E +A RI + +
Sbjct: 238 AGPYNRLVGEIMQETGTRINIPP---PSVNRTEIVFTGEKEQLAQAVARI------KKIY 288
Query: 460 NPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVR 517
K++ + V S VIG G ++ E+ T V +P + +E VI+R
Sbjct: 289 EEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIP--PSDSISETVILR 344
Score = 42.7 bits (99), Expect = 9e-04
Identities = 39/171 (22%), Positives = 73/171 (42%), Gaps = 14/171 (8%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
+ + +P + ++IG +G I++I ++ V IH G+ V I +A
Sbjct: 656 VEVSIPAKLHNSLIGTKGRLIRSIMEECGG-VHIHFPVE-GSGSDTVVIRGPSSDVEKAK 713
Query: 256 RMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQD 315
+ +L + E K + + I A LIGK G ++K+ TG ++ + +D
Sbjct: 714 KQLLHLA-----EEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAED 768
Query: 316 LSIYNPERTITVKGTVEACASAEIE---IMKKLREAFENDMLAVNTHSGYF 363
+ IT+ G +A A+ E +++ L E+ ML H +F
Sbjct: 769 ----KDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHF 815
Score = 41.6 bits (96), Expect = 0.002
Identities = 33/121 (27%), Positives = 55/121 (45%), Gaps = 11/121 (9%)
Query: 188 QARQID-----FPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPV 242
QA Q D F L + V ++ IIG++G I I + + K++ + +
Sbjct: 1042 QAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQI 1101
Query: 243 TIHATPEGTSEACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEH 302
TI + T A IL I+ + E ++E++PL H R+IG G+ ++KI
Sbjct: 1102 TITGYEKNTEAARDAILRIVGEL--EQMVSEDVPLDHRVH----ARIIGARGKAIRKIMD 1155
Query: 303 E 303
E
Sbjct: 1156 E 1156
Score = 41.2 bits (95), Expect = 0.003
Identities = 69/340 (20%), Positives = 136/340 (40%), Gaps = 67/340 (19%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDI-HRKENSGAAEKPVTIHATPE----- 249
L +P +F +++G +G I+ IT+ ++ R+EN+ + +PV E
Sbjct: 876 LECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGR 935
Query: 250 -------GTSEACRMILEIMQKEADET-KLAEE----IPLKILAHNGLVGRLIGKEGRNL 297
G+ C +I+ +KE E K A E + +++ L +IG++G +
Sbjct: 936 EAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGI 995
Query: 298 KKI--EHETGTKITISSLQDLSIYNPERTITVKGTVEACASAEIEIMKKLREA-FENDML 354
+K+ E E + LQ I + G A+ ++++++E E +
Sbjct: 996 RKMMDEFEVNIHVPAPELQS-------DIIAITGLAANLDRAKAGLLERVKELQAEQEDR 1048
Query: 355 AVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFA 414
A+ + +++ + + IIG+KGA I Q+
Sbjct: 1049 ALRSFK--------------------------LSVTVDPKYHPKIIGRKGAVITQIRLEH 1082
Query: 415 GASIKIAPAEGPDVSERMVIITG---PPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHI 471
+I+ + + + + ITG EA A RI G+L++ E+V L+ +
Sbjct: 1083 DVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQM----VSEDVPLDHRV 1138
Query: 472 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDEN 511
R+IG GK + ++ + ++ P+ PD N
Sbjct: 1139 HA------RIIGARGKAIRKIMDEFKVDIRFPQSGAPDPN 1172
Score = 33.1 bits (74), Expect = 0.69
Identities = 59/288 (20%), Positives = 114/288 (39%), Gaps = 63/288 (21%)
Query: 208 IIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEACRMILEIMQKEAD 267
+IG +G +++ I ++T V+I S + + V + PE +A + E+ K
Sbjct: 310 VIGPKGNSLQEILERTGVSVEI---PPSDSISETVILRGEPEKLGQA---LTEVYAKANS 363
Query: 268 ETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITV 327
T + + A + L +IGK+G+NL KI + K+ I + E IT+
Sbjct: 364 FTVSS------VAAPSWLHRFIIGKKGQNLAKITQQM-PKVHIEFTEG------EDKITL 410
Query: 328 KGTVEACASAEIEIMKKLREAFEN-DMLAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEI 386
+G E A+ +I +++ D + +N H+F H H
Sbjct: 411 EGPTEDVNVAQEQIEGMVKDLINRMDYVEINI----------DHKF----HRH------- 449
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+IGK GA+I ++ S++I P ++ I G P+ +A+
Sbjct: 450 ------------LIGKSGANINRIKDQYKVSVRIPP---DSEKSNLIRIEGDPQGVQQAK 494
Query: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQN 494
+ K+ + + R +IG+ G+ + E+++
Sbjct: 495 RELLELASRMENERTKDLIIEQRFHRT-------IIGQKGERIREIRD 535
>gi|145312259 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 2e-09
Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ + +P +AV IIG++GA+IKQL + GA I + + D ER+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
Query: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 506
I L E + + VP + GR+IG+GG+T+ + + A++ ++
Sbjct: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
Query: 507 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
E ++ R+I + I+++V + E+
Sbjct: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
D + + VP + V IIG++G IK + KQT +R+D+ ++ E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
Query: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312
+ C+ I Q + T ++E++ + VGR+IG+ G ++ I +G KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
+ ++ R I + GT + A+A+ I++K+ E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/223 (23%), Positives = 96/223 (43%), Gaps = 47/223 (21%)
Query: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
IL +E+ E +L ++I +++ V +IG++G N+K++ +TG +I +
Sbjct: 32 ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
Query: 314 QDLSIYNPERTITVKG-TVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQF 372
D ER + + G V+ C + +A + +L NT
Sbjct: 89 -DTEDVGDERVLLISGFPVQVCKA----------KAAIHQILTENT-------------- 123
Query: 373 GPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSER 431
P E L +P ++VG IIG+ G I+ + + +GA I +EG + R
Sbjct: 124 ---------PVSE--QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
Query: 432 MVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVP 474
++ I+G + A+ I K+ E+ ++ + A RVP
Sbjct: 173 LIKISGTQKEVAAAKHLILEKVSEDE--ELRKRIAHSAETRVP 213
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 464 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 523
E +E +RVP +IG+ G + +L+ T A + V T D +E ++ I G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
Query: 524 ASQTAQRKIREIVQQ 538
A+ I +I+ +
Sbjct: 107 QVCKAKAAIHQILTE 121
>gi|145312270 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 2e-09
Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ + +P +AV IIG++GA+IKQL + GA I + + D ER+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
Query: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 506
I L E + + VP + GR+IG+GG+T+ + + A++ ++
Sbjct: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
Query: 507 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
E ++ R+I + I+++V + E+
Sbjct: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
D + + VP + V IIG++G IK + KQT +R+D+ ++ E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
Query: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312
+ C+ I Q + T ++E++ + VGR+IG+ G ++ I +G KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
+ ++ R I + GT + A+A+ I++K+ E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/223 (23%), Positives = 96/223 (43%), Gaps = 47/223 (21%)
Query: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
IL +E+ E +L ++I +++ V +IG++G N+K++ +TG +I +
Sbjct: 32 ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
Query: 314 QDLSIYNPERTITVKG-TVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQF 372
D ER + + G V+ C + +A + +L NT
Sbjct: 89 -DTEDVGDERVLLISGFPVQVCKA----------KAAIHQILTENT-------------- 123
Query: 373 GPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSER 431
P E L +P ++VG IIG+ G I+ + + +GA I +EG + R
Sbjct: 124 ---------PVSE--QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
Query: 432 MVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVP 474
++ I+G + A+ I K+ E+ ++ + A RVP
Sbjct: 173 LIKISGTQKEVAAAKHLILEKVSEDE--ELRKRIAHSAETRVP 213
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 464 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 523
E +E +RVP +IG+ G + +L+ T A + V T D +E ++ I G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
Query: 524 ASQTAQRKIREIVQQ 538
A+ I +I+ +
Sbjct: 107 QVCKAKAAIHQILTE 121
>gi|145312256 tudor and KH domain containing isoform a [Homo
sapiens]
Length = 561
Score = 61.2 bits (147), Expect = 2e-09
Identities = 42/158 (26%), Positives = 79/158 (50%), Gaps = 13/158 (8%)
Query: 387 VNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPEAQFKAQ 446
+ + +P +AV IIG++GA+IKQL + GA I + + D ER+++I+G P KA+
Sbjct: 55 IEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFPVQVCKAK 112
Query: 447 GRIFGKLKEENFFNPKEEVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQ 506
I L E + + VP + GR+IG+GG+T+ + + A++ ++
Sbjct: 113 AAIHQIL--------TENTPVSEQLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKE- 163
Query: 507 TPDENEEVIVRIIGHFFASQTAQRKIREIVQQVKQQEQ 544
E ++ R+I + I+++V + E+
Sbjct: 164 --SEGTLLLSRLIKISGTQKEVAAAKHLILEKVSEDEE 199
Score = 59.7 bits (143), Expect = 7e-09
Identities = 43/155 (27%), Positives = 79/155 (50%), Gaps = 10/155 (6%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
D + + VP + V IIG++G IK + KQT +R+D+ ++ E+ + I P
Sbjct: 52 DIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDVDTEDVGD--ERVLLISGFP---V 106
Query: 253 EACRMILEIMQKEADETKLAEEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISS 312
+ C+ I Q + T ++E++ + VGR+IG+ G ++ I +G KIT
Sbjct: 107 QVCKAKAAIHQILTENTPVSEQLSVP----QRSVGRIIGRGGETIRSICKASGAKITCDK 162
Query: 313 LQDLSIYNPERTITVKGTVEACASAEIEIMKKLRE 347
+ ++ R I + GT + A+A+ I++K+ E
Sbjct: 163 ESEGTLL-LSRLIKISGTQKEVAAAKHLILEKVSE 196
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/223 (23%), Positives = 96/223 (43%), Gaps = 47/223 (21%)
Query: 258 ILEIMQKEADETKLA----EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSL 313
IL +E+ E +L ++I +++ V +IG++G N+K++ +TG +I +
Sbjct: 32 ILYRRYRESREERLTFVGEDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV--- 88
Query: 314 QDLSIYNPERTITVKG-TVEACASAEIEIMKKLREAFENDMLAVNTHSGYFSSLYPHHQF 372
D ER + + G V+ C + +A + +L NT
Sbjct: 89 -DTEDVGDERVLLISGFPVQVCKA----------KAAIHQILTENT-------------- 123
Query: 373 GPFPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSER 431
P E L +P ++VG IIG+ G I+ + + +GA I +EG + R
Sbjct: 124 ---------PVSE--QLSVPQRSVGRIIGRGGETIRSICKASGAKITCDKESEGTLLLSR 172
Query: 432 MVIITGPPEAQFKAQGRIFGKLKEENFFNPKEEVKLEAHIRVP 474
++ I+G + A+ I K+ E+ ++ + A RVP
Sbjct: 173 LIKISGTQKEVAAAKHLILEKVSEDE--ELRKRIAHSAETRVP 213
Score = 31.2 bits (69), Expect = 2.6
Identities = 20/75 (26%), Positives = 35/75 (46%), Gaps = 3/75 (4%)
Query: 464 EVKLEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFF 523
E +E +RVP +IG+ G + +L+ T A + V T D +E ++ I G
Sbjct: 50 EDDIEIEMRVPQEAVKLIIGRQGANIKQLRKQTGARIDV---DTEDVGDERVLLISGFPV 106
Query: 524 ASQTAQRKIREIVQQ 538
A+ I +I+ +
Sbjct: 107 QVCKAKAAIHQILTE 121
>gi|14165439 heterogeneous nuclear ribonucleoprotein K isoform a
[Homo sapiens]
Length = 464
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/169 (25%), Positives = 74/169 (43%), Gaps = 10/169 (5%)
Query: 273 EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVE 332
E + L+IL + G +IGK G+N+K + + +++ PER +++ +E
Sbjct: 41 EMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERILSISADIE 95
Query: 333 ACASAEIEIMKKLREAFENDM-LAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFI 391
EI+KK+ E + L T + + + H+ + L I
Sbjct: 96 TIG----EILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLI 151
Query: 392 PTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPE 440
G IIG KGA IK+L +IK+ P ++R+V+I G P+
Sbjct: 152 HQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPD 200
Score = 47.0 bits (110), Expect = 5e-05
Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 29/158 (18%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
LRIL+ ++ GA+IGK G IK + + V + +S E+ ++I A E E
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV---PDSSGPERILSISADIETIGEIL 101
Query: 256 RMILEIMQK---------------EADETKLAE---------EIPLKILAHNGLVGRLIG 291
+ I+ +++ E+D + + L++L H L G +IG
Sbjct: 102 KKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIG 161
Query: 292 KEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKG 329
+G +K++ T T TI Q+ ++ +R + + G
Sbjct: 162 VKGAKIKELRENTQT--TIKLFQECCPHSTDRVVLIGG 197
Score = 42.7 bits (99), Expect = 9e-04
Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSERMVIITGPPEAQFKAQGRI 449
IP G+IIGK G IKQ+ +GASIKI P EG + +R++ ITG + AQ +
Sbjct: 394 IPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSE--DRIITITGTQDQIQNAQYLL 451
Query: 450 FGKLKE 455
+K+
Sbjct: 452 QNSVKQ 457
Score = 39.3 bits (90), Expect = 0.010
Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 26/165 (15%)
Query: 375 FPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVI 434
F + E + + + ++ GA+IGK G +IK L AS+ + + GP ER++
Sbjct: 33 FKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILS 89
Query: 435 ITGPPEAQFKAQGRIFGKLKEE----------------------NFFNPK-EEVKLEAHI 471
I+ E + +I L+E N+ + K + E +
Sbjct: 90 ISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRL 149
Query: 472 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIV 516
+ S AG +IG G + EL+ T + + ++ P + V++
Sbjct: 150 LIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVL 194
Score = 39.3 bits (90), Expect = 0.010
Identities = 19/72 (26%), Positives = 39/72 (54%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
D LR+L+ G IIG +G IK + + TQ+ + + ++ + ++ V I P+
Sbjct: 144 DCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVV 203
Query: 253 EACRMILEIMQK 264
E ++IL+++ +
Sbjct: 204 ECIKIILDLISE 215
Score = 38.5 bits (88), Expect = 0.016
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
I ++ L G +IGK G+ +K+I HE+G I I + S +R IT+ GT +
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGS---EDRIITITGTQDQI 444
Query: 335 ASAEIEIMKKLRE 347
+A+ + +++
Sbjct: 445 QNAQYLLQNSVKQ 457
Score = 38.1 bits (87), Expect = 0.021
Identities = 20/77 (25%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Query: 467 LEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQ 526
+ + +P AG +IGKGG+ + ++++ + A + + D+ + +E+ I+ I G Q
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
Query: 527 TAQRKIREIVQQVKQQE 543
AQ ++ V+Q E
Sbjct: 446 NAQYLLQNSVKQYADVE 462
Score = 36.2 bits (82), Expect = 0.081
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 7/67 (10%)
Query: 450 FGK-----LKEENFFNPKEEVK--LEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV 502
FGK ++EE F +E I + S AG VIGKGGK + L+ +A V V
Sbjct: 19 FGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78
Query: 503 PRDQTPD 509
P P+
Sbjct: 79 PDSSGPE 85
Score = 35.4 bits (80), Expect = 0.14
Identities = 31/135 (22%), Positives = 56/135 (41%), Gaps = 10/135 (7%)
Query: 142 GHQFENYSFKISYIPDE------EVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFP 195
G + Y + + DE + SPS Q A S GG + P
Sbjct: 327 GRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGP 386
Query: 196 L---RILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
+ ++ +P G+IIGK G IK I ++ + + I + G+ ++ +TI T +
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID-EPLEGSEDRIITITGTQDQIQ 445
Query: 253 EACRMILEIMQKEAD 267
A ++ +++ AD
Sbjct: 446 NAQYLLQNSVKQYAD 460
>gi|14165435 heterogeneous nuclear ribonucleoprotein K isoform b
[Homo sapiens]
Length = 463
Score = 54.3 bits (129), Expect = 3e-07
Identities = 43/169 (25%), Positives = 74/169 (43%), Gaps = 10/169 (5%)
Query: 273 EEIPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVE 332
E + L+IL + G +IGK G+N+K + + +++ PER +++ +E
Sbjct: 41 EMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSS-----GPERILSISADIE 95
Query: 333 ACASAEIEIMKKLREAFENDM-LAVNTHSGYFSSLYPHHQFGPFPHHHSYPEQEIVNLFI 391
EI+KK+ E + L T + + + H+ + L I
Sbjct: 96 TIG----EILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLI 151
Query: 392 PTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVIITGPPE 440
G IIG KGA IK+L +IK+ P ++R+V+I G P+
Sbjct: 152 HQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPD 200
Score = 47.0 bits (110), Expect = 5e-05
Identities = 38/158 (24%), Positives = 70/158 (44%), Gaps = 29/158 (18%)
Query: 196 LRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTSEAC 255
LRIL+ ++ GA+IGK G IK + + V + +S E+ ++I A E E
Sbjct: 45 LRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV---PDSSGPERILSISADIETIGEIL 101
Query: 256 RMILEIMQK---------------EADETKLAE---------EIPLKILAHNGLVGRLIG 291
+ I+ +++ E+D + + L++L H L G +IG
Sbjct: 102 KKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRLLIHQSLAGGIIG 161
Query: 292 KEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKG 329
+G +K++ T T TI Q+ ++ +R + + G
Sbjct: 162 VKGAKIKELRENTQT--TIKLFQECCPHSTDRVVLIGG 197
Score = 42.7 bits (99), Expect = 9e-04
Identities = 27/66 (40%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 391 IPTQAVGAIIGKKGAHIKQLARFAGASIKI-APAEGPDVSERMVIITGPPEAQFKAQGRI 449
IP G+IIGK G IKQ+ +GASIKI P EG + +R++ ITG + AQ +
Sbjct: 394 IPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGSE--DRIITITGTQDQIQNAQYLL 451
Query: 450 FGKLKE 455
+K+
Sbjct: 452 QNSVKQ 457
Score = 39.3 bits (90), Expect = 0.010
Identities = 36/165 (21%), Positives = 68/165 (41%), Gaps = 26/165 (15%)
Query: 375 FPHHHSYPEQEIVNLFIPTQAVGAIIGKKGAHIKQLARFAGASIKIAPAEGPDVSERMVI 434
F + E + + + ++ GA+IGK G +IK L AS+ + + GP ER++
Sbjct: 33 FKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSVPDSSGP---ERILS 89
Query: 435 ITGPPEAQFKAQGRIFGKLKEE----------------------NFFNPK-EEVKLEAHI 471
I+ E + +I L+E N+ + K + E +
Sbjct: 90 ISADIETIGEILKKIIPTLEEGLQLPSPTATSQLPLESDAVECLNYQHYKGSDFDCELRL 149
Query: 472 RVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIV 516
+ S AG +IG G + EL+ T + + ++ P + V++
Sbjct: 150 LIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVL 194
Score = 39.3 bits (90), Expect = 0.010
Identities = 19/72 (26%), Positives = 39/72 (54%)
Query: 193 DFPLRILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
D LR+L+ G IIG +G IK + + TQ+ + + ++ + ++ V I P+
Sbjct: 144 DCELRLLIHQSLAGGIIGVKGAKIKELRENTQTTIKLFQECCPHSTDRVVLIGGKPDRVV 203
Query: 253 EACRMILEIMQK 264
E ++IL+++ +
Sbjct: 204 ECIKIILDLISE 215
Score = 38.5 bits (88), Expect = 0.016
Identities = 21/73 (28%), Positives = 38/73 (52%), Gaps = 3/73 (4%)
Query: 275 IPLKILAHNGLVGRLIGKEGRNLKKIEHETGTKITISSLQDLSIYNPERTITVKGTVEAC 334
I ++ L G +IGK G+ +K+I HE+G I I + S +R IT+ GT +
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKIDEPLEGS---EDRIITITGTQDQI 444
Query: 335 ASAEIEIMKKLRE 347
+A+ + +++
Sbjct: 445 QNAQYLLQNSVKQ 457
Score = 37.7 bits (86), Expect = 0.028
Identities = 19/72 (26%), Positives = 40/72 (55%), Gaps = 2/72 (2%)
Query: 467 LEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIVPRDQTPDENEEVIVRIIGHFFASQ 526
+ + +P AG +IGKGG+ + ++++ + A + + D+ + +E+ I+ I G Q
Sbjct: 388 ITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKI--DEPLEGSEDRIITITGTQDQIQ 445
Query: 527 TAQRKIREIVQQ 538
AQ ++ V+Q
Sbjct: 446 NAQYLLQNSVKQ 457
Score = 36.2 bits (82), Expect = 0.081
Identities = 24/67 (35%), Positives = 32/67 (47%), Gaps = 7/67 (10%)
Query: 450 FGK-----LKEENFFNPKEEVK--LEAHIRVPSSTAGRVIGKGGKTVNELQNLTSAEVIV 502
FGK ++EE F +E I + S AG VIGKGGK + L+ +A V V
Sbjct: 19 FGKRPAEDMEEEQAFKRSRNTDEMVELRILLQSKNAGAVIGKGGKNIKALRTDYNASVSV 78
Query: 503 PRDQTPD 509
P P+
Sbjct: 79 PDSSGPE 85
Score = 33.1 bits (74), Expect = 0.69
Identities = 29/122 (23%), Positives = 49/122 (40%), Gaps = 10/122 (8%)
Query: 142 GHQFENYSFKISYIPDE------EVSSPSPPQRAQRGDHSSREQGHAPGGTSQARQIDFP 195
G + Y + + DE + SPS Q A S GG + P
Sbjct: 327 GRPGDRYDGMVGFSADETWDSAIDTWSPSEWQMAYEPQGGSGYDYSYAGGRGSYGDLGGP 386
Query: 196 L---RILVPTQFVGAIIGKEGLTIKNITKQTQSRVDIHRKENSGAAEKPVTIHATPEGTS 252
+ ++ +P G+IIGK G IK I ++ + + I + G+ ++ +TI T +
Sbjct: 387 IITTQVTIPKDLAGSIIGKGGQRIKQIRHESGASIKID-EPLEGSEDRIITITGTQDQIQ 445
Query: 253 EA 254
A
Sbjct: 446 NA 447
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.132 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,683,124
Number of Sequences: 37866
Number of extensions: 923606
Number of successful extensions: 3081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 84
Number of HSP's successfully gapped in prelim test: 117
Number of HSP's that attempted gapping in prelim test: 2437
Number of HSP's gapped (non-prelim): 550
length of query: 556
length of database: 18,247,518
effective HSP length: 107
effective length of query: 449
effective length of database: 14,195,856
effective search space: 6373939344
effective search space used: 6373939344
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.