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Search of human proteins with 134133292
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|134133292 WD repeat domain 27 [Homo sapiens]
(857 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|134133292 WD repeat domain 27 [Homo sapiens] 1734 0.0
gi|23199987 WD repeat domain 5B [Homo sapiens] 84 4e-16
gi|16554629 WD repeat domain 5 [Homo sapiens] 80 1e-14
gi|16554627 WD repeat domain 5 [Homo sapiens] 80 1e-14
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 74 4e-13
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 65 3e-10
gi|21071067 TBP-associated factor 5 [Homo sapiens] 63 1e-09
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 60 7e-09
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 60 7e-09
gi|169403944 WD repeat domain 26 isoform b [Homo sapiens] 59 1e-08
gi|55743153 WD repeat domain 26 isoform a [Homo sapiens] 59 1e-08
gi|241896935 WD repeat domain 25 [Homo sapiens] 57 1e-07
gi|241896933 WD repeat domain 25 [Homo sapiens] 57 1e-07
gi|19913367 transducin beta-like 1Y [Homo sapiens] 57 1e-07
gi|19913365 transducin beta-like 1Y [Homo sapiens] 57 1e-07
gi|15150805 transducin beta-like 1Y [Homo sapiens] 57 1e-07
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 55 3e-07
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 54 5e-07
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 54 5e-07
gi|189571685 WD repeat, sterile alpha motif and U-box domain con... 54 5e-07
gi|189571683 WD repeat, sterile alpha motif and U-box domain con... 54 5e-07
gi|189571681 WD repeat, sterile alpha motif and U-box domain con... 54 5e-07
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 53 1e-06
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 53 1e-06
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 53 1e-06
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 53 1e-06
gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo sapi... 52 2e-06
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 52 3e-06
gi|113865883 WD repeat domain 38 [Homo sapiens] 51 4e-06
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 51 5e-06
>gi|134133292 WD repeat domain 27 [Homo sapiens]
Length = 857
Score = 1734 bits (4491), Expect = 0.0
Identities = 857/857 (100%), Positives = 857/857 (100%)
Query: 1 MENPQDIFSSNGGCLSDIVIEKYLVESKESVSHVQLACSMQDCAFPLDGTELCIWNTKDP 60
MENPQDIFSSNGGCLSDIVIEKYLVESKESVSHVQLACSMQDCAFPLDGTELCIWNTKDP
Sbjct: 1 MENPQDIFSSNGGCLSDIVIEKYLVESKESVSHVQLACSMQDCAFPLDGTELCIWNTKDP 60
Query: 61 SHQLLILRGHHQPITAMAFGNKVNPLLICSASLDYVIMWNLDECREKVLQGLVPRGTVMG 120
SHQLLILRGHHQPITAMAFGNKVNPLLICSASLDYVIMWNLDECREKVLQGLVPRGTVMG
Sbjct: 61 SHQLLILRGHHQPITAMAFGNKVNPLLICSASLDYVIMWNLDECREKVLQGLVPRGTVMG 120
Query: 121 SLLGKVLCLQLSLDDHVVAVCAGNKIFMLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTF 180
SLLGKVLCLQLSLDDHVVAVCAGNKIFMLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTF
Sbjct: 121 SLLGKVLCLQLSLDDHVVAVCAGNKIFMLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTF 180
Query: 181 SQTQAVRAELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYP 240
SQTQAVRAELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYP
Sbjct: 181 SQTQAVRAELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYP 240
Query: 241 LLSLFIDAESRQLVTGCADGQLWIFSLMDGHHYRRVARVDLRKKTETFSTRRVKSGLCSQ 300
LLSLFIDAESRQLVTGCADGQLWIFSLMDGHHYRRVARVDLRKKTETFSTRRVKSGLCSQ
Sbjct: 241 LLSLFIDAESRQLVTGCADGQLWIFSLMDGHHYRRVARVDLRKKTETFSTRRVKSGLCSQ 300
Query: 301 PEESQLPSTSALGKGEQVEVTFPVLRLAPCDLSLIPNSACGCLSSENTRCVWIGSSVGLF 360
PEESQLPSTSALGKGEQVEVTFPVLRLAPCDLSLIPNSACGCLSSENTRCVWIGSSVGLF
Sbjct: 301 PEESQLPSTSALGKGEQVEVTFPVLRLAPCDLSLIPNSACGCLSSENTRCVWIGSSVGLF 360
Query: 361 VFNLANLEVEAALYYKDFQSLSILLAGSCALRNRTADQKVLCLLASLFGGKIAVLEINPA 420
VFNLANLEVEAALYYKDFQSLSILLAGSCALRNRTADQKVLCLLASLFGGKIAVLEINPA
Sbjct: 361 VFNLANLEVEAALYYKDFQSLSILLAGSCALRNRTADQKVLCLLASLFGGKIAVLEINPA 420
Query: 421 ALVRAQQCPSMGQSLSVPASSCVLPTSPLYLGIAKEKSTKAASEQRRAARNVMKDQRLVF 480
ALVRAQQCPSMGQSLSVPASSCVLPTSPLYLGIAKEKSTKAASEQRRAARNVMKDQRLVF
Sbjct: 421 ALVRAQQCPSMGQSLSVPASSCVLPTSPLYLGIAKEKSTKAASEQRRAARNVMKDQRLVF 480
Query: 481 HSKVRSSGYASAPHVTMFSPKTNIKSEGKGSSRSRSSCAREAYPVECAVPTKPGPQVAAA 540
HSKVRSSGYASAPHVTMFSPKTNIKSEGKGSSRSRSSCAREAYPVECAVPTKPGPQVAAA
Sbjct: 481 HSKVRSSGYASAPHVTMFSPKTNIKSEGKGSSRSRSSCAREAYPVECAVPTKPGPQVAAA 540
Query: 541 PTCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWL 600
PTCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWL
Sbjct: 541 PTCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWL 600
Query: 601 LSAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHID 660
LSAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHID
Sbjct: 601 LSAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHID 660
Query: 661 TCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAG 720
TCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAG
Sbjct: 661 TCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAG 720
Query: 721 CSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFE 780
CSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFE
Sbjct: 721 CSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFE 780
Query: 781 GHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAP 840
GHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAP
Sbjct: 781 GHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAP 840
Query: 841 QLATATLDGKLQLFLAE 857
QLATATLDGKLQLFLAE
Sbjct: 841 QLATATLDGKLQLFLAE 857
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 84.3 bits (207), Expect = 4e-16
Identities = 74/306 (24%), Positives = 129/306 (42%), Gaps = 34/306 (11%)
Query: 546 VCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAAR 605
V +++S +G+WLA A+ L++++ A GH+ ++ V WS D L+SA+
Sbjct: 44 VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103
Query: 606 DGTLRMWSARGAE-LALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCKD 664
D TL++W R + L L G + + P L+ I D
Sbjct: 104 DKTLKLWDVRSGKCLKTLKGHSNY--------------VFCCNFNPPSNLI---ISGSFD 146
Query: 665 EIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGR-NRTVEVFDLNAGCSA 723
E + + K + LS +SAV+ S ++ +G + ++D +G
Sbjct: 147 ETVKIWEVKTGKCLKTLSAHS----DPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCL 202
Query: 724 AVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHP 783
+ + + PV SF P LT + + ++LWD RC + + GH
Sbjct: 203 KTLVDDDNPPV---------SFVKFSPNG-KYILTATLDNTLKLWDYSRGRCLKTYTGHK 252
Query: 784 TRGYPCGIAFSPCG-RFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQL 842
Y FS G ++ G+ED Y++ + + +L GHTD V A +P+ +
Sbjct: 253 NEKYCIFANFSVTGGKWIVSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISAACHPTENLI 312
Query: 843 ATATLD 848
A+A L+
Sbjct: 313 ASAALE 318
Score = 47.0 bits (110), Expect = 8e-05
Identities = 23/90 (25%), Positives = 46/90 (51%), Gaps = 2/90 (2%)
Query: 765 MRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLA 824
++LWD+R+ +C + +GH + C F+P G+ D ++E+ + L+
Sbjct: 107 LKLWDVRSGKCLKTLKGHSNYVFCCN--FNPPSNLIISGSFDETVKIWEVKTGKCLKTLS 164
Query: 825 GHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
H+D V+ V FN S + + + DG +++
Sbjct: 165 AHSDPVSAVHFNCSGSLIVSGSYDGLCRIW 194
Score = 38.5 bits (88), Expect = 0.027
Identities = 32/153 (20%), Positives = 70/153 (45%), Gaps = 14/153 (9%)
Query: 703 VLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIG 762
+++A ++T++++D+ +G + + HS V N S NL ++ +
Sbjct: 98 LVSASDDKTLKLWDVRSGKCLKTL-KGHSNYVFCCNFNPPS----------NLIISGSFD 146
Query: 763 DGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHR 822
+ +++W+++T +C + H + F+ G G+ D +++ S
Sbjct: 147 ETVKIWEVKTGKCLKTLSAHSDP--VSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKT 204
Query: 823 LAGHTDT-VTGVAFNPSAPQLATATLDGKLQLF 854
L + V+ V F+P+ + TATLD L+L+
Sbjct: 205 LVDDDNPPVSFVKFSPNGKYILTATLDNTLKLW 237
Score = 32.7 bits (73), Expect = 1.5
Identities = 17/64 (26%), Positives = 33/64 (51%)
Query: 791 IAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGK 850
+ FSP G + A + DR ++ + L GH ++ VA++ + +L +A+ D
Sbjct: 47 VKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASDDKT 106
Query: 851 LQLF 854
L+L+
Sbjct: 107 LKLW 110
Score = 31.6 bits (70), Expect = 3.3
Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Query: 190 LQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFIDAE 249
L+GH V F P + +IS S D K+W+ TG + + S S P+ ++ +
Sbjct: 121 LKGHSNYVFCCNFNP-PSNLIISGSFDETVKIWEVKTGKCLKTLSAHSD-PVSAVHFNCS 178
Query: 250 SRQLVTGCADGQLWIFSLMDG 270
+V+G DG I+ G
Sbjct: 179 GSLIVSGSYDGLCRIWDAASG 199
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 79.7 bits (195), Expect = 1e-14
Identities = 80/348 (22%), Positives = 141/348 (40%), Gaps = 38/348 (10%)
Query: 505 KSEGKGSSRSRSSCAREAYPVECAVPTKPGPQV--AAAPTCTRVCCIQYSGDGQWLACGL 562
++E + + SS A ++ P P KP + A V +++S +G+WLA
Sbjct: 9 ETEAARAQPTPSSSATQSKPT----PVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSS 64
Query: 563 ANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWS-ARGAELAL 621
A+ L+ ++ A SGH ++ V WS D L+SA+ D TL++W + G L
Sbjct: 65 ADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKT 124
Query: 622 LLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLICRL 681
L G + + P+ L+ + DE R K C
Sbjct: 125 LKGHSNY--------------VFCCNFNPQSNLI---VSGSFDESVRIWDVKTGK--CLK 165
Query: 682 STTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNK 741
+ D S N S +++++ + ++D +G + + + PV
Sbjct: 166 TLPAHSDPVSAVHFNRDGS-LIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV------- 217
Query: 742 GSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCG-RFA 800
SF P L + + ++LWD +C + + GH Y FS G ++
Sbjct: 218 --SFVKFSPNG-KYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWI 274
Query: 801 ACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLD 848
G+ED Y++ + + +L GHTD V A +P+ +A+A L+
Sbjct: 275 VSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALE 322
Score = 44.3 bits (103), Expect = 5e-04
Identities = 21/101 (20%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
Query: 754 NLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYE 813
NL ++ + +++WD+ + +C + +GH + C F+P G+ D +++
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCN--FNPQSNLIVSGSFDESVRIWD 157
Query: 814 MGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
+ + L H+D V+ V FN + +++ DG +++
Sbjct: 158 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 41.6 bits (96), Expect = 0.003
Identities = 35/156 (22%), Positives = 75/156 (48%), Gaps = 14/156 (8%)
Query: 700 SHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTT 759
S+++++A ++T++++D+++G + + HS V C N PQ+ NL ++
Sbjct: 99 SNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYV--FCCNFN-------PQS-NLIVSG 147
Query: 760 AIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTF 819
+ + +R+WD++T +C + H + F+ G + D +++ S
Sbjct: 148 SFDESVRIWDVKTGKCLKTLPAHSDP--VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQC 205
Query: 820 SHRLAGHTDT-VTGVAFNPSAPQLATATLDGKLQLF 854
L + V+ V F+P+ + ATLD L+L+
Sbjct: 206 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW 241
Score = 31.2 bits (69), Expect = 4.3
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 210 LISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFIDAESRQLVTGCADGQLWIFSLMD 269
L+SAS+D+ K+WD +G + + S Y F + +S +V+G D + I+ +
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNF-NPQSNLIVSGSFDESVRIWDVKT 160
Query: 270 G 270
G
Sbjct: 161 G 161
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 79.7 bits (195), Expect = 1e-14
Identities = 80/348 (22%), Positives = 141/348 (40%), Gaps = 38/348 (10%)
Query: 505 KSEGKGSSRSRSSCAREAYPVECAVPTKPGPQV--AAAPTCTRVCCIQYSGDGQWLACGL 562
++E + + SS A ++ P P KP + A V +++S +G+WLA
Sbjct: 9 ETEAARAQPTPSSSATQSKPT----PVKPNYALKFTLAGHTKAVSSVKFSPNGEWLASSS 64
Query: 563 ANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWS-ARGAELAL 621
A+ L+ ++ A SGH ++ V WS D L+SA+ D TL++W + G L
Sbjct: 65 ADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKT 124
Query: 622 LLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLICRL 681
L G + + P+ L+ + DE R K C
Sbjct: 125 LKGHSNY--------------VFCCNFNPQSNLI---VSGSFDESVRIWDVKTGK--CLK 165
Query: 682 STTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNK 741
+ D S N S +++++ + ++D +G + + + PV
Sbjct: 166 TLPAHSDPVSAVHFNRDGS-LIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPV------- 217
Query: 742 GSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCG-RFA 800
SF P L + + ++LWD +C + + GH Y FS G ++
Sbjct: 218 --SFVKFSPNG-KYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWI 274
Query: 801 ACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLD 848
G+ED Y++ + + +L GHTD V A +P+ +A+A L+
Sbjct: 275 VSGSEDNLVYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALE 322
Score = 44.3 bits (103), Expect = 5e-04
Identities = 21/101 (20%), Positives = 49/101 (48%), Gaps = 2/101 (1%)
Query: 754 NLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYE 813
NL ++ + +++WD+ + +C + +GH + C F+P G+ D +++
Sbjct: 100 NLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCN--FNPQSNLIVSGSFDESVRIWD 157
Query: 814 MGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
+ + L H+D V+ V FN + +++ DG +++
Sbjct: 158 VKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198
Score = 41.6 bits (96), Expect = 0.003
Identities = 35/156 (22%), Positives = 75/156 (48%), Gaps = 14/156 (8%)
Query: 700 SHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTT 759
S+++++A ++T++++D+++G + + HS V C N PQ+ NL ++
Sbjct: 99 SNLLVSASDDKTLKIWDVSSGKCLKTL-KGHSNYV--FCCNFN-------PQS-NLIVSG 147
Query: 760 AIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTF 819
+ + +R+WD++T +C + H + F+ G + D +++ S
Sbjct: 148 SFDESVRIWDVKTGKCLKTLPAHSDP--VSAVHFNRDGSLIVSSSYDGLCRIWDTASGQC 205
Query: 820 SHRLAGHTDT-VTGVAFNPSAPQLATATLDGKLQLF 854
L + V+ V F+P+ + ATLD L+L+
Sbjct: 206 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLW 241
Score = 31.2 bits (69), Expect = 4.3
Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Query: 210 LISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFIDAESRQLVTGCADGQLWIFSLMD 269
L+SAS+D+ K+WD +G + + S Y F + +S +V+G D + I+ +
Sbjct: 102 LVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNF-NPQSNLIVSGSFDESVRIWDVKT 160
Query: 270 G 270
G
Sbjct: 161 G 161
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 74.3 bits (181), Expect = 4e-13
Identities = 82/356 (23%), Positives = 149/356 (41%), Gaps = 45/356 (12%)
Query: 508 GKGSSRSRSSCAREAYPVECAVPTKPGPQVAAAPTCTRVCCIQYSGDGQWLACGLANHLL 567
G G ++ +A P C+ + P + + V C ++ +G LA + L+
Sbjct: 33 GAGQQQATPGALLQAGPPRCS--SLQAPIMLLSGHEGEVYCCKFHPNGSTLASAGFDRLI 90
Query: 568 LVFDA-SLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMW-SARGAELALLLGK 625
L+++ A GH GAV + ++ D L SA+ D T+ +W S G + L G
Sbjct: 91 LLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGH 150
Query: 626 DMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCKDE--IKRYKQKSKSKLICRLST 683
F A+ GP+ + T D+ +K + + K+ + +T
Sbjct: 151 TSFVNSCYPAR-----------RGPQL------VCTGSDDGTVKLWDIRKKAAIQTFQNT 193
Query: 684 TGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGS 743
+ +T ND I+ + G + ++V+DL H+ V + +
Sbjct: 194 YQVLAVT----FNDTSDQII-SGGIDNDIKVWDLRQN-KLTYTMRGHADSVTGLSLSSEG 247
Query: 744 SFTTQQPQAYNLFLTTAIGDGMRLWDLRTL----RCERHFEG--HPTRGYPCGIAFSPCG 797
S+ L+ A+ + +R+WD+R RC + F+G H ++SP G
Sbjct: 248 SY----------LLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDG 297
Query: 798 RFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQL 853
A G+ DR YV++ S ++L GH ++ VAF+P P + +A+ D +L +
Sbjct: 298 SKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSDKRLYM 353
Score = 33.9 bits (76), Expect = 0.66
Identities = 20/97 (20%), Positives = 44/97 (45%), Gaps = 4/97 (4%)
Query: 759 TAIGDG-MRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSS 817
T DG ++LWD+R + F+ + F+ G D V+++ +
Sbjct: 169 TGSDDGTVKLWDIRKKAAIQTFQN---TYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQN 225
Query: 818 TFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
++ + GH D+VTG++ + L + +D ++++
Sbjct: 226 KLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVW 262
Score = 31.6 bits (70), Expect = 3.3
Identities = 30/84 (35%), Positives = 38/84 (45%), Gaps = 15/84 (17%)
Query: 188 AELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLI-----YSSSVLSAYPLL 242
A L+GH G V + + L SAS D+ VWD TG + ++S V S YP
Sbjct: 103 ATLKGHSGAVMELHYNT-DGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPA- 160
Query: 243 SLFIDAESRQLV-TGCADG--QLW 263
QLV TG DG +LW
Sbjct: 161 -----RRGPQLVCTGSDDGTVKLW 179
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 64.7 bits (156), Expect = 3e-10
Identities = 32/101 (31%), Positives = 55/101 (54%), Gaps = 2/101 (1%)
Query: 754 NLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYE 813
N T + +RLW + R F GH RG +AFSP G++ A ED+ +++
Sbjct: 439 NYLATGSTDKTVRLWSAQQGNSVRLFTGH--RGPVLSLAFSPNGKYLASAGEDQRLKLWD 496
Query: 814 MGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
+ S T L GHTD +T + F+P + +A+A++D ++++
Sbjct: 497 LASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVW 537
Score = 42.7 bits (99), Expect = 0.001
Identities = 48/217 (22%), Positives = 87/217 (40%), Gaps = 64/217 (29%)
Query: 546 VCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAAR 605
V C+++ + +LA G + + ++ A + +F+GH G V ++ +S + ++L SA
Sbjct: 429 VDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGE 488
Query: 606 DGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCKDE 665
D L++W L+SG ++ LR H D
Sbjct: 489 DQRLKLWD--------------------------------LASGTLYKELRGHTD----- 511
Query: 666 IKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDL-NAGCSAA 724
++TSL+ D S ++ +A + +V V+D+ N CSA
Sbjct: 512 ----------------------NITSLTFSPD--SGLIASASMDNSVRVWDIRNTYCSAP 547
Query: 725 VIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAI 761
A+ S + + + S+ + Q A NL L T I
Sbjct: 548 --ADGSSSELVGVYTGQMSNVLSVQFMACNLLLVTGI 582
Score = 41.2 bits (95), Expect = 0.004
Identities = 28/94 (29%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 765 MRLWDLRTLRCERHFEGHPTRGYPC-GIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRL 823
+R WDL + ++GH YP + SP + A G+ DR A ++ +
Sbjct: 366 IRYWDLGSFTNTVLYQGH---AYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYPLRIY 422
Query: 824 AGHTDTVTGVAFNPSAPQLATATLDGKLQLFLAE 857
AGH V V F+P++ LAT + D ++L+ A+
Sbjct: 423 AGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQ 456
Score = 40.0 bits (92), Expect = 0.009
Identities = 28/80 (35%), Positives = 39/80 (48%), Gaps = 8/80 (10%)
Query: 190 LQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWD--HCTGSLIYSSSVLSAYPLLSLFID 247
L+GH GPV + F +G L+S SED + WD T +++Y AYP+ L I
Sbjct: 338 LRGHCGPVYSTRFLADSSG-LLSCSEDMSIRYWDLGSFTNTVLYQG---HAYPVWDLDIS 393
Query: 248 AESRQLVTGCAD--GQLWIF 265
S +G D +LW F
Sbjct: 394 PYSLYFASGSHDRTARLWSF 413
Score = 38.9 bits (89), Expect = 0.021
Identities = 34/153 (22%), Positives = 63/153 (41%), Gaps = 15/153 (9%)
Query: 703 VLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIG 762
+L+ + ++ +DL + + V+ + H+ PV + Y+L+ +
Sbjct: 357 LLSCSEDMSIRYWDLGSFTNT-VLYQGHAYPVWDL-----------DISPYSLYFASGSH 404
Query: 763 DGM-RLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSH 821
D RLW R + GH C + F P + A G+ D+ ++
Sbjct: 405 DRTARLWSFDRTYPLRIYAGH-LADVDC-VKFHPNSNYLATGSTDKTVRLWSAQQGNSVR 462
Query: 822 RLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
GH V +AF+P+ LA+A D +L+L+
Sbjct: 463 LFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLW 495
Score = 36.2 bits (82), Expect = 0.13
Identities = 53/212 (25%), Positives = 79/212 (37%), Gaps = 33/212 (15%)
Query: 31 VSHVQLACSM---QDCAFPLDGTELCIWNTKDPSHQLLILRGHHQPITAMAFGNKVNPLL 87
VS + LAC + +D GTE+ ILRGH P+ + F + LL
Sbjct: 311 VSRIHLACDILEEEDDEDDNAGTEM------------KILRGHCGPVYSTRFLADSSGLL 358
Query: 88 ICSASLDYVIMWNLDECREKVLQGLVPRGTVMGSLLGKVLCLQLSLDDHVVAVCAGNKIF 147
CS + + W+L VL + L D + + ++ +
Sbjct: 359 SCSEDMS-IRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTY 417
Query: 148 MLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTFSQTQAVRAE----------LQGHLGPV 197
L R ++ D H P +L T S + VR GH GPV
Sbjct: 418 PL----RIYAGHLADVDCVKFH--PNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPV 471
Query: 198 TAVEFCPWRAGTLISASEDRGFKVWDHCTGSL 229
++ F P L SA ED+ K+WD +G+L
Sbjct: 472 LSLAFSP-NGKYLASAGEDQRLKLWDLASGTL 502
Score = 33.5 bits (75), Expect = 0.86
Identities = 20/52 (38%), Positives = 29/52 (55%), Gaps = 5/52 (9%)
Query: 189 ELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWD----HCTGSLIYSSSVL 236
EL+GH +T++ F P +G + SAS D +VWD +C+ SSS L
Sbjct: 505 ELRGHTDNITSLTFSP-DSGLIASASMDNSVRVWDIRNTYCSAPADGSSSEL 555
Score = 32.7 bits (73), Expect = 1.5
Identities = 27/129 (20%), Positives = 54/129 (41%), Gaps = 11/129 (8%)
Query: 487 SGYASAPHVTMFSPKTNIKSEGKGSSRSRSSCAREAYPVECAVPTKPGPQVAAAPTCTRV 546
+G+ + F P +N + G R A++ V + GP ++ A
Sbjct: 423 AGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHR-GPVLSLA------ 475
Query: 547 CCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARD 606
+S +G++LA + L ++D + GH + ++ +S D + SA+ D
Sbjct: 476 ----FSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMD 531
Query: 607 GTLRMWSAR 615
++R+W R
Sbjct: 532 NSVRVWDIR 540
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 63.2 bits (152), Expect = 1e-09
Identities = 40/132 (30%), Positives = 62/132 (46%), Gaps = 2/132 (1%)
Query: 723 AAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGH 782
A + A H +P+ + T+ N T + +RLWD+ C R F GH
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGH 668
Query: 783 PTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQL 842
+G + FSP GRF A GA D ++++G L GHTDTV + F+ L
Sbjct: 669 --KGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEIL 726
Query: 843 ATATLDGKLQLF 854
A+ ++D ++L+
Sbjct: 727 ASGSMDNTVRLW 738
Score = 52.4 bits (124), Expect = 2e-06
Identities = 64/256 (25%), Positives = 93/256 (36%), Gaps = 54/256 (21%)
Query: 569 VFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGAELALLLGKDMF 628
+ D + GH G V +S DR +LLS++ DGT+R+WS + L+G
Sbjct: 527 IMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQ--TFTCLVGYKGH 584
Query: 629 SKPIQSAQF----YYI-----DAFILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLIC 679
+ P+ QF YY D L + +Q LR D
Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLAD--------------- 629
Query: 680 RLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFD-LNAGCSAAVIAEAHSRPVHQIC 738
V+ T S+ V +RTV ++D LN C I H P+H +
Sbjct: 630 -------VNCTRFHP----NSNYVATGSADRTVRLWDVLNGNC--VRIFTGHKGPIHSL- 675
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDG-MRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCG 797
T P FL T DG + LWD+ +GH C + FS G
Sbjct: 676 --------TFSPN--GRFLATGATDGRVLLWDIGHGLMVGELKGHTDT--VCSLRFSRDG 723
Query: 798 RFAACGAEDRHAYVYE 813
A G+ D +++
Sbjct: 724 EILASGSMDNTVRLWD 739
Score = 49.7 bits (117), Expect = 1e-05
Identities = 38/130 (29%), Positives = 60/130 (46%), Gaps = 14/130 (10%)
Query: 726 IAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTR 785
I HS PV+ G+SF+ + N L+++ +RLW L+T C ++GH
Sbjct: 538 ILYGHSGPVY------GASFSPDR----NYLLSSSEDGTVRLWSLQTFTCLVGYKGH--- 584
Query: 786 GYPC-GIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLAT 844
YP FSP G + G DR A ++ AGH V F+P++ +AT
Sbjct: 585 NYPVWDTQFSPYGYYFVSGGHDRVARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVAT 644
Query: 845 ATLDGKLQLF 854
+ D ++L+
Sbjct: 645 GSADRTVRLW 654
Score = 40.4 bits (93), Expect = 0.007
Identities = 17/67 (25%), Positives = 38/67 (56%)
Query: 546 VCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAAR 605
V C ++ + ++A G A+ + ++D +F+GH G ++++ +S + R+L + A
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689
Query: 606 DGTLRMW 612
DG + +W
Sbjct: 690 DGRVLLW 696
Score = 36.2 bits (82), Expect = 0.13
Identities = 19/66 (28%), Positives = 35/66 (53%)
Query: 549 IQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGT 608
+ +S +G++LA G + +L++D GH V ++ +S+D L S + D T
Sbjct: 675 LTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNT 734
Query: 609 LRMWSA 614
+R+W A
Sbjct: 735 VRLWDA 740
Score = 35.4 bits (80), Expect = 0.23
Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 6/81 (7%)
Query: 192 GHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAY--PLLSLFIDAE 249
GHL V F P + + + S DR ++WD G+ + + + + P+ SL
Sbjct: 625 GHLADVNCTRFHP-NSNYVATGSADRTVRLWDVLNGNCV---RIFTGHKGPIHSLTFSPN 680
Query: 250 SRQLVTGCADGQLWIFSLMDG 270
R L TG DG++ ++ + G
Sbjct: 681 GRFLATGATDGRVLLWDIGHG 701
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 60.5 bits (145), Expect = 7e-09
Identities = 61/311 (19%), Positives = 125/311 (40%), Gaps = 36/311 (11%)
Query: 546 VCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAAR 605
V C+ +S + + LA G + L+V+ F+GH AV V +S L S +R
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 606 DGTLRMW--SARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCK 663
D T+R+W + +G + ++S F S G F +
Sbjct: 82 DKTVRIWVPNVKGESTVFRA----HTATVRSVHF--------CSDGQSF------VTASD 123
Query: 664 DEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSA 723
D+ + + K + LS ++ + + ++++A ++TV+++D
Sbjct: 124 DKTVKVWATHRQKFLFSLSQH--INWVRCAKFSPD-GRLIVSASDDKTVKLWD------- 173
Query: 724 AVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHP 783
++ VH C++ G + + + +++WD+RT R +H++ H
Sbjct: 174 ----KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS 229
Query: 784 TRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLA 843
G++F P G + + D + ++ + L GH T VAF+ + A
Sbjct: 230 AAVN--GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
Query: 844 TATLDGKLQLF 854
+ D ++ ++
Sbjct: 288 SGGSDEQVMVW 298
Score = 44.3 bits (103), Expect = 5e-04
Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 776 ERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAF 835
ERHF+GH R + FS + A G+ D V+ M + ++R GH D VT V F
Sbjct: 12 ERHFKGH--RDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNF 69
Query: 836 NPSAPQLATATLDGKLQLFL 855
+PS LA+ + D +++++
Sbjct: 70 SPSGHLLASGSRDKTVRIWV 89
Score = 32.0 bits (71), Expect = 2.5
Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 26/179 (14%)
Query: 68 RGHHQPITAMAFGNKVNPLLICSASLDYVIM-WNLDECREKVLQGLVPRGTVMGSLLGKV 126
+GH +T + F +N + S S+D +M W++ Q R T V
Sbjct: 16 KGHRDAVTCVDFS--INTKQLASGSMDSCLMVWHMKP------QSRAYRFT---GHKDAV 64
Query: 127 LCLQLSLDDHVVAVCAGNK---IFMLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTFSQT 183
C+ S H++A + +K I++ +++ +V V + H T S
Sbjct: 65 TCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDD 124
Query: 184 QAVRA----------ELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYS 232
+ V+ L H+ V +F P ++SAS+D+ K+WD + ++S
Sbjct: 125 KTVKVWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHS 182
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 60.5 bits (145), Expect = 7e-09
Identities = 61/311 (19%), Positives = 125/311 (40%), Gaps = 36/311 (11%)
Query: 546 VCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAAR 605
V C+ +S + + LA G + L+V+ F+GH AV V +S L S +R
Sbjct: 22 VTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSR 81
Query: 606 DGTLRMW--SARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCK 663
D T+R+W + +G + ++S F S G F +
Sbjct: 82 DKTVRIWVPNVKGESTVFRA----HTATVRSVHF--------CSDGQSF------VTASD 123
Query: 664 DEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSA 723
D+ + + K + LS ++ + + ++++A ++TV+++D
Sbjct: 124 DKTVKVWATHRQKFLFSLSQH--INWVRCAKFSPD-GRLIVSASDDKTVKLWD------- 173
Query: 724 AVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHP 783
++ VH C++ G + + + +++WD+RT R +H++ H
Sbjct: 174 ----KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS 229
Query: 784 TRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLA 843
G++F P G + + D + ++ + L GH T VAF+ + A
Sbjct: 230 AAVN--GLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFA 287
Query: 844 TATLDGKLQLF 854
+ D ++ ++
Sbjct: 288 SGGSDEQVMVW 298
Score = 44.3 bits (103), Expect = 5e-04
Identities = 27/80 (33%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Query: 776 ERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAF 835
ERHF+GH R + FS + A G+ D V+ M + ++R GH D VT V F
Sbjct: 12 ERHFKGH--RDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNF 69
Query: 836 NPSAPQLATATLDGKLQLFL 855
+PS LA+ + D +++++
Sbjct: 70 SPSGHLLASGSRDKTVRIWV 89
Score = 32.0 bits (71), Expect = 2.5
Identities = 39/179 (21%), Positives = 72/179 (40%), Gaps = 26/179 (14%)
Query: 68 RGHHQPITAMAFGNKVNPLLICSASLDYVIM-WNLDECREKVLQGLVPRGTVMGSLLGKV 126
+GH +T + F +N + S S+D +M W++ Q R T V
Sbjct: 16 KGHRDAVTCVDFS--INTKQLASGSMDSCLMVWHMKP------QSRAYRFT---GHKDAV 64
Query: 127 LCLQLSLDDHVVAVCAGNK---IFMLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTFSQT 183
C+ S H++A + +K I++ +++ +V V + H T S
Sbjct: 65 TCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDD 124
Query: 184 QAVRA----------ELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYS 232
+ V+ L H+ V +F P ++SAS+D+ K+WD + ++S
Sbjct: 125 KTVKVWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHS 182
>gi|169403944 WD repeat domain 26 isoform b [Homo sapiens]
Length = 498
Score = 59.3 bits (142), Expect = 1e-08
Identities = 70/320 (21%), Positives = 122/320 (38%), Gaps = 41/320 (12%)
Query: 543 CTRVCCIQYSGDGQWLACGLANHLLLVF----DASLTGTPAVFSGHDGAVNAVCWSQDRR 598
C V ++S DG LA G + ++++ D L GH V+ + WS D
Sbjct: 192 CNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDN 251
Query: 599 WLLSAARD--GTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLR 656
+L++ D L +W+ + EL + + A + D ++ G Q +
Sbjct: 252 YLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVA--WNPDGKRFVTGGQRGQFYQ 309
Query: 657 YHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFD 716
+D L + V + L ++D VLA+ ++ + ++
Sbjct: 310 CDLDGNL-----------------LDSWEGVRVQCLWCLSD--GKTVLASDTHQRIRGYN 350
Query: 717 LNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCE 776
++ E H P+ +K L L G+ LWDL+
Sbjct: 351 FEDLTDRNIVQEDH--PIMSFTISKNG----------RLALLNVATQGVHLWDLQDRVLV 398
Query: 777 RHFEGHPTRGYPCGIAFSPCGR-FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAF 835
R ++G Y F F A G+ED Y++ S L GHT TV V++
Sbjct: 399 RKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSW 458
Query: 836 NPSAP-QLATATLDGKLQLF 854
NP P +A+A+ DG ++++
Sbjct: 459 NPQIPSMMASASDDGTVRIW 478
>gi|55743153 WD repeat domain 26 isoform a [Homo sapiens]
Length = 514
Score = 59.3 bits (142), Expect = 1e-08
Identities = 70/320 (21%), Positives = 122/320 (38%), Gaps = 41/320 (12%)
Query: 543 CTRVCCIQYSGDGQWLACGLANHLLLVF----DASLTGTPAVFSGHDGAVNAVCWSQDRR 598
C V ++S DG LA G + ++++ D L GH V+ + WS D
Sbjct: 208 CNEVWFCKFSNDGTKLATGSKDTTVIIWQVDPDTHLLKLLKTLEGHAYGVSYIAWSPDDN 267
Query: 599 WLLSAARD--GTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLR 656
+L++ D L +W+ + EL + + A + D ++ G Q +
Sbjct: 268 YLVACGPDDCSELWLWNVQTGELRTKMSQSHEDSLTSVA--WNPDGKRFVTGGQRGQFYQ 325
Query: 657 YHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFD 716
+D L + V + L ++D VLA+ ++ + ++
Sbjct: 326 CDLDGNL-----------------LDSWEGVRVQCLWCLSD--GKTVLASDTHQRIRGYN 366
Query: 717 LNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCE 776
++ E H P+ +K L L G+ LWDL+
Sbjct: 367 FEDLTDRNIVQEDH--PIMSFTISKNG----------RLALLNVATQGVHLWDLQDRVLV 414
Query: 777 RHFEGHPTRGYPCGIAFSPCGR-FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAF 835
R ++G Y F F A G+ED Y++ S L GHT TV V++
Sbjct: 415 RKYQGVTQGFYTIHSCFGGHNEDFIASGSEDHKVYIWHKRSELPIAELTGHTRTVNCVSW 474
Query: 836 NPSAP-QLATATLDGKLQLF 854
NP P +A+A+ DG ++++
Sbjct: 475 NPQIPSMMASASDDGTVRIW 494
>gi|241896935 WD repeat domain 25 [Homo sapiens]
Length = 544
Score = 56.6 bits (135), Expect = 1e-07
Identities = 75/314 (23%), Positives = 121/314 (38%), Gaps = 38/314 (12%)
Query: 556 QWLACGLANHLLLV--FDASLTGTPAVFSGH--------DGAVNAVCWSQDRRWLLSAAR 605
QW +H+LL D + AV SGH AV A W+ R +LS
Sbjct: 253 QWCPVLSKSHMLLSTSMDKTFKVWNAVDSGHCLQTYSLHTEAVRAARWAPCGRRILSGGF 312
Query: 606 DGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCKDE 665
D L + L G+ F I + +F+ D I L G ++ + I T K
Sbjct: 313 DFALHLTDLETGT-QLFSGRSDFR--ITTLKFHPKDHNIFLCGGFSSEMKAWDIRTGK-V 368
Query: 666 IKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAV 725
++ YK + L G+ ++S A +RT+ +D
Sbjct: 369 MRSYKATIQQTLDILFLREGSEFLSSTDAST--------RDSADRTIIAWDFRTS----- 415
Query: 726 IAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRL----WDLRTLRCERHFEG 781
A+ ++ H+ + ++P +FL G+ + L W R R R +EG
Sbjct: 416 -AKISNQIFHERFTCPSLALHPREP----VFLAQTNGNYLALFSTVWPYRMSR-RRRYEG 469
Query: 782 HPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQ 841
H GY G SP G G+ D +Y +++ + L GHT G ++P P
Sbjct: 470 HKVEGYSVGCECSPGGDLLVTGSADGRVLMYSFRTASRACTLQGHTQACVGTTYHPVLPS 529
Query: 842 -LATATLDGKLQLF 854
LAT + G ++++
Sbjct: 530 VLATCSWGGDMKIW 543
Score = 38.5 bits (88), Expect = 0.027
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 190 LQGHLGPVTAVEFCP--WRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFID 247
L+GH GPV +++CP ++ L+S S D+ FKVW + + S L Y L + +
Sbjct: 242 LRGHRGPVNTIQWCPVLSKSHMLLSTSMDKTFKVW-----NAVDSGHCLQTYSLHTEAVR 296
Query: 248 AE-----SRQLVTGCADGQLWIFSLMDGHHYRRVARVDLRKKTETFSTRRVKSGLC 298
A R++++G D L + L G R D R T F + LC
Sbjct: 297 AARWAPCGRRILSGGFDFALHLTDLETGTQLFS-GRSDFRITTLKFHPKDHNIFLC 351
>gi|241896933 WD repeat domain 25 [Homo sapiens]
Length = 544
Score = 56.6 bits (135), Expect = 1e-07
Identities = 75/314 (23%), Positives = 121/314 (38%), Gaps = 38/314 (12%)
Query: 556 QWLACGLANHLLLV--FDASLTGTPAVFSGH--------DGAVNAVCWSQDRRWLLSAAR 605
QW +H+LL D + AV SGH AV A W+ R +LS
Sbjct: 253 QWCPVLSKSHMLLSTSMDKTFKVWNAVDSGHCLQTYSLHTEAVRAARWAPCGRRILSGGF 312
Query: 606 DGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCKDE 665
D L + L G+ F I + +F+ D I L G ++ + I T K
Sbjct: 313 DFALHLTDLETGT-QLFSGRSDFR--ITTLKFHPKDHNIFLCGGFSSEMKAWDIRTGK-V 368
Query: 666 IKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAV 725
++ YK + L G+ ++S A +RT+ +D
Sbjct: 369 MRSYKATIQQTLDILFLREGSEFLSSTDAST--------RDSADRTIIAWDFRTS----- 415
Query: 726 IAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRL----WDLRTLRCERHFEG 781
A+ ++ H+ + ++P +FL G+ + L W R R R +EG
Sbjct: 416 -AKISNQIFHERFTCPSLALHPREP----VFLAQTNGNYLALFSTVWPYRMSR-RRRYEG 469
Query: 782 HPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQ 841
H GY G SP G G+ D +Y +++ + L GHT G ++P P
Sbjct: 470 HKVEGYSVGCECSPGGDLLVTGSADGRVLMYSFRTASRACTLQGHTQACVGTTYHPVLPS 529
Query: 842 -LATATLDGKLQLF 854
LAT + G ++++
Sbjct: 530 VLATCSWGGDMKIW 543
Score = 38.5 bits (88), Expect = 0.027
Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 13/116 (11%)
Query: 190 LQGHLGPVTAVEFCP--WRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFID 247
L+GH GPV +++CP ++ L+S S D+ FKVW + + S L Y L + +
Sbjct: 242 LRGHRGPVNTIQWCPVLSKSHMLLSTSMDKTFKVW-----NAVDSGHCLQTYSLHTEAVR 296
Query: 248 AE-----SRQLVTGCADGQLWIFSLMDGHHYRRVARVDLRKKTETFSTRRVKSGLC 298
A R++++G D L + L G R D R T F + LC
Sbjct: 297 AARWAPCGRRILSGGFDFALHLTDLETGTQLFS-GRSDFRITTLKFHPKDHNIFLC 351
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 56.6 bits (135), Expect = 1e-07
Identities = 74/375 (19%), Positives = 148/375 (39%), Gaps = 45/375 (12%)
Query: 488 GYASAPHVTMFSPKTNIKSEGKGSSRSR------SSCAREAYPVECAVPTKPGPQVAAAP 541
G+ S + ++P +++ + G G S +R +S V + G V P
Sbjct: 177 GHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV---P 233
Query: 542 TCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLL 601
+ V + ++ DG LA G + ++ + + H G + A+ W++ ++L
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIWTEN-GNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 602 SAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYID-----AFILLSSGPEFQLLR 656
SA D T +W A E K F P SA +D F S+ + R
Sbjct: 293 SAGVDKTTIIWDAHTGE-----AKQQF--PFHSAPALDVDWQNNMTFASCSTDMCIHVCR 345
Query: 657 YHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFD 716
C +K ++ + + +G + L++ +D + T++++
Sbjct: 346 LG---CDHPVKTFQGHTNEVNAIKWDPSGML----LASCSD-----------DMTLKIWS 387
Query: 717 LNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCE 776
+ + +AHS+ ++ I + T P + + + + +RLWD+ C
Sbjct: 388 MKQDACVHDL-QAHSKEIYTIKWSPTGP-ATSNPNSSIMLASASFDSTVRLWDVEQGVCT 445
Query: 777 RHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFN 836
H Y +AFSP G++ A G+ D++ +++ S + H G T + V +N
Sbjct: 446 HTLMKHQEPVY--SVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWN 502
Query: 837 PSAPQLATATLDGKL 851
++ + DG +
Sbjct: 503 ARGDKVGASASDGSV 517
Score = 36.2 bits (82), Expect = 0.13
Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 3/116 (2%)
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGR 798
Q+KG F + + N L+ + +WD T ++ F H + +
Sbjct: 274 QHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD--VDWQNNMT 331
Query: 799 FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
FA+C D +V +G GHT+ V + ++PS LA+ + D L+++
Sbjct: 332 FASCST-DMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 386
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 56.6 bits (135), Expect = 1e-07
Identities = 74/375 (19%), Positives = 148/375 (39%), Gaps = 45/375 (12%)
Query: 488 GYASAPHVTMFSPKTNIKSEGKGSSRSR------SSCAREAYPVECAVPTKPGPQVAAAP 541
G+ S + ++P +++ + G G S +R +S V + G V P
Sbjct: 177 GHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV---P 233
Query: 542 TCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLL 601
+ V + ++ DG LA G + ++ + + H G + A+ W++ ++L
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIWTEN-GNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 602 SAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYID-----AFILLSSGPEFQLLR 656
SA D T +W A E K F P SA +D F S+ + R
Sbjct: 293 SAGVDKTTIIWDAHTGE-----AKQQF--PFHSAPALDVDWQNNMTFASCSTDMCIHVCR 345
Query: 657 YHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFD 716
C +K ++ + + +G + L++ +D + T++++
Sbjct: 346 LG---CDHPVKTFQGHTNEVNAIKWDPSGML----LASCSD-----------DMTLKIWS 387
Query: 717 LNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCE 776
+ + +AHS+ ++ I + T P + + + + +RLWD+ C
Sbjct: 388 MKQDACVHDL-QAHSKEIYTIKWSPTGP-ATSNPNSSIMLASASFDSTVRLWDVEQGVCT 445
Query: 777 RHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFN 836
H Y +AFSP G++ A G+ D++ +++ S + H G T + V +N
Sbjct: 446 HTLMKHQEPVY--SVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWN 502
Query: 837 PSAPQLATATLDGKL 851
++ + DG +
Sbjct: 503 ARGDKVGASASDGSV 517
Score = 36.2 bits (82), Expect = 0.13
Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 3/116 (2%)
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGR 798
Q+KG F + + N L+ + +WD T ++ F H + +
Sbjct: 274 QHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD--VDWQNNMT 331
Query: 799 FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
FA+C D +V +G GHT+ V + ++PS LA+ + D L+++
Sbjct: 332 FASCST-DMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 386
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 56.6 bits (135), Expect = 1e-07
Identities = 74/375 (19%), Positives = 148/375 (39%), Gaps = 45/375 (12%)
Query: 488 GYASAPHVTMFSPKTNIKSEGKGSSRSR------SSCAREAYPVECAVPTKPGPQVAAAP 541
G+ S + ++P +++ + G G S +R +S V + G V P
Sbjct: 177 GHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV---P 233
Query: 542 TCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLL 601
+ V + ++ DG LA G + ++ + + H G + A+ W++ ++L
Sbjct: 234 SNKDVTSLDWNSDGTLLAMGSYDGFARIWTEN-GNLASTLGQHKGPIFALKWNKKGNYVL 292
Query: 602 SAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYID-----AFILLSSGPEFQLLR 656
SA D T +W A E K F P SA +D F S+ + R
Sbjct: 293 SAGVDKTTIIWDAHTGE-----AKQQF--PFHSAPALDVDWQNNMTFASCSTDMCIHVCR 345
Query: 657 YHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFD 716
C +K ++ + + +G + L++ +D + T++++
Sbjct: 346 LG---CDHPVKTFQGHTNEVNAIKWDPSGML----LASCSD-----------DMTLKIWS 387
Query: 717 LNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCE 776
+ + +AHS+ ++ I + T P + + + + +RLWD+ C
Sbjct: 388 MKQDACVHDL-QAHSKEIYTIKWSPTGP-ATSNPNSSIMLASASFDSTVRLWDVEQGVCT 445
Query: 777 RHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFN 836
H Y +AFSP G++ A G+ D++ +++ S + H G T + V +N
Sbjct: 446 HTLMKHQEPVY--SVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG-TGGIFEVCWN 502
Query: 837 PSAPQLATATLDGKL 851
++ + DG +
Sbjct: 503 ARGDKVGASASDGSV 517
Score = 36.2 bits (82), Expect = 0.13
Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 3/116 (2%)
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGR 798
Q+KG F + + N L+ + +WD T ++ F H + +
Sbjct: 274 QHKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD--VDWQNNMT 331
Query: 799 FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
FA+C D +V +G GHT+ V + ++PS LA+ + D L+++
Sbjct: 332 FASCST-DMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 386
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/99 (32%), Positives = 51/99 (51%), Gaps = 3/99 (3%)
Query: 757 LTTAIGDG-MRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMG 815
L T+ GD ++LWDL C FEGH + C + CG F A + D+ + ++++
Sbjct: 409 LATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSC--TWHSCGNFVASSSLDKTSKIWDVN 466
Query: 816 SSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
S L GHTD+V + F P + L T++ D L ++
Sbjct: 467 SERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIW 505
Score = 35.8 bits (81), Expect = 0.17
Identities = 29/144 (20%), Positives = 56/144 (38%), Gaps = 13/144 (9%)
Query: 711 TVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDL 770
TV+++DL G + E HSR V + +F ++++ ++WD+
Sbjct: 417 TVKLWDLCKG-DCILTFEGHSRAVWSCTWHSCGNFVA----------SSSLDKTSKIWDV 465
Query: 771 RTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTV 830
+ RC GH I F P + D+ +++ + L GH ++
Sbjct: 466 NSERCRCTLYGHTDSVN--SIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHSI 523
Query: 831 TGVAFNPSAPQLATATLDGKLQLF 854
F+P +A+ G +L+
Sbjct: 524 NDAIFDPRGHMIASCDACGVTKLW 547
Score = 35.8 bits (81), Expect = 0.17
Identities = 16/45 (35%), Positives = 27/45 (60%), Gaps = 1/45 (2%)
Query: 183 TQAVRAELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTG 227
++ R L GH V ++EF P+ + TL+++S D+ +WD TG
Sbjct: 467 SERCRCTLYGHTDSVNSIEFFPF-SNTLLTSSADKTLSIWDARTG 510
Score = 34.7 bits (78), Expect = 0.39
Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 1/65 (1%)
Query: 549 IQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGT 608
+ + G+ LA N ++ + D +G GH+ + V +S D L S DGT
Sbjct: 568 VNFDSSGRVLAQASGNGVIHLLDLK-SGEIHKLMGHENEAHTVVFSHDGEILFSGGSDGT 626
Query: 609 LRMWS 613
+R WS
Sbjct: 627 VRTWS 631
Score = 32.7 bits (73), Expect = 1.5
Identities = 32/129 (24%), Positives = 53/129 (41%), Gaps = 15/129 (11%)
Query: 500 PKTNIKSEGKGSSRSRSSCAREAYPVECAVPTKPGPQ-VAAAPTCTRVCCIQYSGDGQ-- 556
PK N+ G G + S C +P + T G V C C + + G +
Sbjct: 382 PKCNVLLTGFGHTDWLSDCC--FHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAV 439
Query: 557 ----WLACG--LANHLL----LVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARD 606
W +CG +A+ L ++D + GH +VN++ + LL+++ D
Sbjct: 440 WSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSAD 499
Query: 607 GTLRMWSAR 615
TL +W AR
Sbjct: 500 KTLSIWDAR 508
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 54.3 bits (129), Expect = 5e-07
Identities = 66/309 (21%), Positives = 122/309 (39%), Gaps = 47/309 (15%)
Query: 554 DGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWS 613
D + G A+ ++VFD S A GH V +V + + + SA+ D T+R+WS
Sbjct: 233 DTNKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWS 292
Query: 614 ARGAELALLLGKDMFSKPIQSAQFYYIDAFILLSSGPEFQLLRYHIDTCKDEIKRYKQKS 673
A ++ + +SA + L ++G Y + + D+ +
Sbjct: 293 VPNASCVQVV------RAHESA----VTGLSLHATGD------YLLSSSDDQYWAFSDIQ 336
Query: 674 KSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAG-RNRTVEVFDLNAGCSAAVIAEAHSR 732
+++ ++ T SL+ ++ G + ++++DL + A HS
Sbjct: 337 TGRVLTKV--TDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANF-PGHSG 393
Query: 733 PVHQICQNKGSSFTTQQPQAYNLFLTTAIGD-GMRLWDLR------TLRCERHFEGHPTR 785
P+ I ++ +L TA D ++LWDLR TL+ + +FE
Sbjct: 394 PITSIAFSEN-----------GYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVK--- 439
Query: 786 GYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATA 845
+ F G + A G D Y+ + + H+ TGVAF A +A+
Sbjct: 440 ----SLIFDQSGTYLALGGTDVQIYICKQWTEIL--HFTEHSGLTTGVAFGHHAKFIAST 493
Query: 846 TLDGKLQLF 854
+D L+ +
Sbjct: 494 GMDRSLKFY 502
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/68 (26%), Positives = 35/68 (51%)
Query: 548 CIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDG 607
C Q+ DG G + + ++D A F GH G + ++ +S++ +L +AA D
Sbjct: 355 CAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAADDS 414
Query: 608 TLRMWSAR 615
++++W R
Sbjct: 415 SVKLWDLR 422
Score = 34.3 bits (77), Expect = 0.51
Identities = 21/77 (27%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 188 AELQGHLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFID 247
A GH GP+T++ F L +A++D K+WD + + + + + SL D
Sbjct: 386 ANFPGHSGPITSIAFSE-NGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIFD 444
Query: 248 AESRQLVTGCADGQLWI 264
L G D Q++I
Sbjct: 445 QSGTYLALGGTDVQIYI 461
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 54.3 bits (129), Expect = 5e-07
Identities = 78/376 (20%), Positives = 150/376 (39%), Gaps = 47/376 (12%)
Query: 488 GYASAPHVTMFSPKTNIKSEGKGSSRSR------SSCAREAYPVECAVPTKPGPQVAAAP 541
G+ S + ++P +++ + G G S +R +S + V + G V P
Sbjct: 167 GHESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDV---P 223
Query: 542 TCTRVCCIQYSGDGQWLACGLANHLLLVF--DASLTGTPAVFSGHDGAVNAVCWSQDRRW 599
+ V + ++ +G LA G + ++ D +L T H G + A+ W++ +
Sbjct: 224 SNKDVTSLDWNSEGTLLATGSYDGFARIWTKDGNLAST---LGQHKGPIFALKWNKKGNF 280
Query: 600 LLSAARDGTLRMWSARGAELALLLGKDMF---SKPIQSAQFYYIDAFILLSSGPEFQLLR 656
+LSA D T +W A E K F S P + + F S+ + +
Sbjct: 281 ILSAGVDKTTIIWDAHTGE-----AKQQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCK 335
Query: 657 YHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFD 716
D IK ++ + + TG +++ + + T++++
Sbjct: 336 LGQDR---PIKTFQGHTNEVNAIKWDPTG---------------NLLASCSDDMTLKIWS 377
Query: 717 LNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDG-MRLWDLRTLRC 775
+ + +AH++ ++ I + T P A NL L +A D +RLWD+ C
Sbjct: 378 MKQD-NCVHDLQAHNKEIYTIKWSPTGP-GTNNPNA-NLMLASASFDSTVRLWDVDRGIC 434
Query: 776 ERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAF 835
H Y +AFSP GR+ A G+ D+ +++ + H G T + V +
Sbjct: 435 IHTLTKHQEPVY--SVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG-TGGIFEVCW 491
Query: 836 NPSAPQLATATLDGKL 851
N + ++ + DG +
Sbjct: 492 NAAGDKVGASASDGSV 507
Score = 38.5 bits (88), Expect = 0.027
Identities = 26/116 (22%), Positives = 51/116 (43%), Gaps = 3/116 (2%)
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGR 798
Q+KG F + + N L+ + +WD T ++ F H + +
Sbjct: 264 QHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPA--LDVDWQSNNT 321
Query: 799 FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
FA+C + D +V ++G GHT+ V + ++P+ LA+ + D L+++
Sbjct: 322 FASC-STDMCIHVCKLGQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTLKIW 376
>gi|189571685 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 54.3 bits (129), Expect = 5e-07
Identities = 63/283 (22%), Positives = 109/283 (38%), Gaps = 39/283 (13%)
Query: 584 HDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAF 643
H AV+ C+S L S + DGT +W+ ++ ++ + S P++ QF D+
Sbjct: 53 HTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGS-PVRVCQFSP-DST 110
Query: 644 ILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIV 703
L S + ++ ++ + K + K S C S G+ +T S +
Sbjct: 111 CLASGAADGTVVLWNAQSYK-LYRCGSVKDGSLAACAFSPNGSFFVTGSSCGD------- 162
Query: 704 LAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQI---CQNKGSSFTTQQPQAYNLFLTTA 760
+ V+D C HS H + C + S + Q F +
Sbjct: 163 --------LTVWDDKMRC-------LHSEKAHDLGITCCDFSSQPVSDGEQGLQFFRLAS 207
Query: 761 IGDG--MRLWDLR-------TLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYV 811
G +++W + L+ + GH C AFS G+ G+ D+ V
Sbjct: 208 CGQDCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLAC--AFSHDGQMLVSGSVDKSVIV 265
Query: 812 YEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
Y+ + H L HT VT AF P+ LAT ++D + ++
Sbjct: 266 YDTNTENILHTLTQHTRYVTTCAFAPNTLLLATGSMDKTVNIW 308
Score = 42.0 bits (97), Expect = 0.002
Identities = 68/290 (23%), Positives = 113/290 (38%), Gaps = 34/290 (11%)
Query: 33 HVQLACSMQDCAFPLDGTELCIWNTKDPSHQLLILRGHHQPITAMAFGNKVNPLLICSAS 92
H+ +CS DGT + +WNT++ ++ + P+ F + L A+
Sbjct: 67 HILASCST-------DGTTV-LWNTENGQMLAVMEQPSGSPVRVCQFSPD-STCLASGAA 117
Query: 93 LDYVIMWNLDECR----EKVLQGLV------PRGT--VMGSLLG-------KVLCLQLS- 132
V++WN + V G + P G+ V GS G K+ CL
Sbjct: 118 DGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLHSEK 177
Query: 133 LDDHVVAVCAGNKIFMLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTFSQTQAVRAELQG 192
D + C + + D EQ + + + K+ +F H ++ L G
Sbjct: 178 AHDLGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIWIVSFTHILGFELKYKSTLSG 237
Query: 193 HLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFIDAESRQ 252
H PV A F L+S S D+ V+D T +++++ + + Y F +
Sbjct: 238 HCAPVLACAF-SHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFA-PNTLL 295
Query: 253 LVTGCADG--QLWIFSLMDGHHYRRVARVDLRKKTETFSTRRVKSGLCSQ 300
L TG D +W F L RR L++ TE +S V + LC+Q
Sbjct: 296 LATGSMDKTVNIWQFDLETLCQARRTEH-QLKQFTEDWSEEDVSTWLCAQ 344
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/70 (22%), Positives = 30/70 (42%)
Query: 543 CTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLS 602
C V +S DGQ L G + ++V+D + + H V ++ + L +
Sbjct: 239 CAPVLACAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLAT 298
Query: 603 AARDGTLRMW 612
+ D T+ +W
Sbjct: 299 GSMDKTVNIW 308
Score = 31.6 bits (70), Expect = 3.3
Identities = 43/181 (23%), Positives = 75/181 (41%), Gaps = 20/181 (11%)
Query: 481 HSKVRSSGYASAPHVTMFSPKTNIKSEGKGSSRSRSSCAREAYPVECAVPTKPGPQVAAA 540
HS ++ YA H FSP +I + SC+ + V V
Sbjct: 47 HSPLKFHTYAV--HCCCFSPSGHILA----------SCSTDGTTVLWNTENGQMLAVMEQ 94
Query: 541 PTCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWL 600
P+ + V Q+S D LA G A+ +++++A S DG++ A +S + +
Sbjct: 95 PSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFF 154
Query: 601 LSAARDGTLRMWSAR----GAELALLLG---KDMFSKPIQSAQFYYIDAFILLSSGPEFQ 653
++ + G L +W + +E A LG D S+P+ + + F L S G + Q
Sbjct: 155 VTGSSCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQPVSDGE-QGLQFFRLASCGQDCQ 213
Query: 654 L 654
+
Sbjct: 214 V 214
>gi|189571683 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 54.3 bits (129), Expect = 5e-07
Identities = 63/283 (22%), Positives = 109/283 (38%), Gaps = 39/283 (13%)
Query: 584 HDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAF 643
H AV+ C+S L S + DGT +W+ ++ ++ + S P++ QF D+
Sbjct: 53 HTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGS-PVRVCQFSP-DST 110
Query: 644 ILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIV 703
L S + ++ ++ + K + K S C S G+ +T S +
Sbjct: 111 CLASGAADGTVVLWNAQSYK-LYRCGSVKDGSLAACAFSPNGSFFVTGSSCGD------- 162
Query: 704 LAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQI---CQNKGSSFTTQQPQAYNLFLTTA 760
+ V+D C HS H + C + S + Q F +
Sbjct: 163 --------LTVWDDKMRC-------LHSEKAHDLGITCCDFSSQPVSDGEQGLQFFRLAS 207
Query: 761 IGDG--MRLWDLR-------TLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYV 811
G +++W + L+ + GH C AFS G+ G+ D+ V
Sbjct: 208 CGQDCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLAC--AFSHDGQMLVSGSVDKSVIV 265
Query: 812 YEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
Y+ + H L HT VT AF P+ LAT ++D + ++
Sbjct: 266 YDTNTENILHTLTQHTRYVTTCAFAPNTLLLATGSMDKTVNIW 308
Score = 42.0 bits (97), Expect = 0.002
Identities = 68/290 (23%), Positives = 113/290 (38%), Gaps = 34/290 (11%)
Query: 33 HVQLACSMQDCAFPLDGTELCIWNTKDPSHQLLILRGHHQPITAMAFGNKVNPLLICSAS 92
H+ +CS DGT + +WNT++ ++ + P+ F + L A+
Sbjct: 67 HILASCST-------DGTTV-LWNTENGQMLAVMEQPSGSPVRVCQFSPD-STCLASGAA 117
Query: 93 LDYVIMWNLDECR----EKVLQGLV------PRGT--VMGSLLG-------KVLCLQLS- 132
V++WN + V G + P G+ V GS G K+ CL
Sbjct: 118 DGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLHSEK 177
Query: 133 LDDHVVAVCAGNKIFMLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTFSQTQAVRAELQG 192
D + C + + D EQ + + + K+ +F H ++ L G
Sbjct: 178 AHDLGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIWIVSFTHILGFELKYKSTLSG 237
Query: 193 HLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFIDAESRQ 252
H PV A F L+S S D+ V+D T +++++ + + Y F +
Sbjct: 238 HCAPVLACAF-SHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFA-PNTLL 295
Query: 253 LVTGCADG--QLWIFSLMDGHHYRRVARVDLRKKTETFSTRRVKSGLCSQ 300
L TG D +W F L RR L++ TE +S V + LC+Q
Sbjct: 296 LATGSMDKTVNIWQFDLETLCQARRTEH-QLKQFTEDWSEEDVSTWLCAQ 344
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/70 (22%), Positives = 30/70 (42%)
Query: 543 CTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLS 602
C V +S DGQ L G + ++V+D + + H V ++ + L +
Sbjct: 239 CAPVLACAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLAT 298
Query: 603 AARDGTLRMW 612
+ D T+ +W
Sbjct: 299 GSMDKTVNIW 308
Score = 31.6 bits (70), Expect = 3.3
Identities = 43/181 (23%), Positives = 75/181 (41%), Gaps = 20/181 (11%)
Query: 481 HSKVRSSGYASAPHVTMFSPKTNIKSEGKGSSRSRSSCAREAYPVECAVPTKPGPQVAAA 540
HS ++ YA H FSP +I + SC+ + V V
Sbjct: 47 HSPLKFHTYAV--HCCCFSPSGHILA----------SCSTDGTTVLWNTENGQMLAVMEQ 94
Query: 541 PTCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWL 600
P+ + V Q+S D LA G A+ +++++A S DG++ A +S + +
Sbjct: 95 PSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFF 154
Query: 601 LSAARDGTLRMWSAR----GAELALLLG---KDMFSKPIQSAQFYYIDAFILLSSGPEFQ 653
++ + G L +W + +E A LG D S+P+ + + F L S G + Q
Sbjct: 155 VTGSSCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQPVSDGE-QGLQFFRLASCGQDCQ 213
Query: 654 L 654
+
Sbjct: 214 V 214
>gi|189571681 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 54.3 bits (129), Expect = 5e-07
Identities = 63/283 (22%), Positives = 109/283 (38%), Gaps = 39/283 (13%)
Query: 584 HDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYIDAF 643
H AV+ C+S L S + DGT +W+ ++ ++ + S P++ QF D+
Sbjct: 53 HTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGS-PVRVCQFSP-DST 110
Query: 644 ILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYSHIV 703
L S + ++ ++ + K + K S C S G+ +T S +
Sbjct: 111 CLASGAADGTVVLWNAQSYK-LYRCGSVKDGSLAACAFSPNGSFFVTGSSCGD------- 162
Query: 704 LAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQI---CQNKGSSFTTQQPQAYNLFLTTA 760
+ V+D C HS H + C + S + Q F +
Sbjct: 163 --------LTVWDDKMRC-------LHSEKAHDLGITCCDFSSQPVSDGEQGLQFFRLAS 207
Query: 761 IGDG--MRLWDLR-------TLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYV 811
G +++W + L+ + GH C AFS G+ G+ D+ V
Sbjct: 208 CGQDCQVKIWIVSFTHILGFELKYKSTLSGHCAPVLAC--AFSHDGQMLVSGSVDKSVIV 265
Query: 812 YEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
Y+ + H L HT VT AF P+ LAT ++D + ++
Sbjct: 266 YDTNTENILHTLTQHTRYVTTCAFAPNTLLLATGSMDKTVNIW 308
Score = 42.0 bits (97), Expect = 0.002
Identities = 68/290 (23%), Positives = 113/290 (38%), Gaps = 34/290 (11%)
Query: 33 HVQLACSMQDCAFPLDGTELCIWNTKDPSHQLLILRGHHQPITAMAFGNKVNPLLICSAS 92
H+ +CS DGT + +WNT++ ++ + P+ F + L A+
Sbjct: 67 HILASCST-------DGTTV-LWNTENGQMLAVMEQPSGSPVRVCQFSPD-STCLASGAA 117
Query: 93 LDYVIMWNLDECR----EKVLQGLV------PRGT--VMGSLLG-------KVLCLQLS- 132
V++WN + V G + P G+ V GS G K+ CL
Sbjct: 118 DGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFFVTGSSCGDLTVWDDKMRCLHSEK 177
Query: 133 LDDHVVAVCAGNKIFMLDIEQRFSVTYIERPDVNNRHKVPPPTFLHTFSQTQAVRAELQG 192
D + C + + D EQ + + + K+ +F H ++ L G
Sbjct: 178 AHDLGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIWIVSFTHILGFELKYKSTLSG 237
Query: 193 HLGPVTAVEFCPWRAGTLISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFIDAESRQ 252
H PV A F L+S S D+ V+D T +++++ + + Y F +
Sbjct: 238 HCAPVLACAF-SHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFA-PNTLL 295
Query: 253 LVTGCADG--QLWIFSLMDGHHYRRVARVDLRKKTETFSTRRVKSGLCSQ 300
L TG D +W F L RR L++ TE +S V + LC+Q
Sbjct: 296 LATGSMDKTVNIWQFDLETLCQARRTEH-QLKQFTEDWSEEDVSTWLCAQ 344
Score = 32.0 bits (71), Expect = 2.5
Identities = 16/70 (22%), Positives = 30/70 (42%)
Query: 543 CTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLS 602
C V +S DGQ L G + ++V+D + + H V ++ + L +
Sbjct: 239 CAPVLACAFSHDGQMLVSGSVDKSVIVYDTNTENILHTLTQHTRYVTTCAFAPNTLLLAT 298
Query: 603 AARDGTLRMW 612
+ D T+ +W
Sbjct: 299 GSMDKTVNIW 308
Score = 31.6 bits (70), Expect = 3.3
Identities = 43/181 (23%), Positives = 75/181 (41%), Gaps = 20/181 (11%)
Query: 481 HSKVRSSGYASAPHVTMFSPKTNIKSEGKGSSRSRSSCAREAYPVECAVPTKPGPQVAAA 540
HS ++ YA H FSP +I + SC+ + V V
Sbjct: 47 HSPLKFHTYAV--HCCCFSPSGHILA----------SCSTDGTTVLWNTENGQMLAVMEQ 94
Query: 541 PTCTRVCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWL 600
P+ + V Q+S D LA G A+ +++++A S DG++ A +S + +
Sbjct: 95 PSGSPVRVCQFSPDSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGSLAACAFSPNGSFF 154
Query: 601 LSAARDGTLRMWSAR----GAELALLLG---KDMFSKPIQSAQFYYIDAFILLSSGPEFQ 653
++ + G L +W + +E A LG D S+P+ + + F L S G + Q
Sbjct: 155 VTGSSCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQPVSDGE-QGLQFFRLASCGQDCQ 213
Query: 654 L 654
+
Sbjct: 214 V 214
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 52.8 bits (125), Expect = 1e-06
Identities = 87/419 (20%), Positives = 158/419 (37%), Gaps = 57/419 (13%)
Query: 454 AKEKSTKAASEQRRA--ARNVMKDQRLVFHSKVRSS------GYASAPHVTMFSPKTNIK 505
+K + E+ RA N K + ++ SS G+ S + ++P +++
Sbjct: 137 SKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLL 196
Query: 506 SEGKGSSRSR------SSCAREAYPVECAVPTKPGPQVAAAPTCTRVCCIQYSGDGQWLA 559
+ G G S +R +S V + G V P+ V + ++ +G LA
Sbjct: 197 ASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV---PSNKDVTSLDWNTNGTLLA 253
Query: 560 CGLANHLLLVF--DASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGA 617
G + ++ D +L T H G + A+ W++ ++LSA D T +W A
Sbjct: 254 TGSYDGFARIWTEDGNLAST---LGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTG 310
Query: 618 ELALLLGKDMFSKPIQSAQFYYID-----AFILLSSGPEFQLLRYHIDTCKDEIKRYKQK 672
E K F P SA +D F S+ + R C +K ++
Sbjct: 311 E-----AKQQF--PFHSAPALDVDWQNNTTFASCSTDMCIHVCRLG---CDRPVKTFQGH 360
Query: 673 SKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSR 732
+ + +G M S +D I + V + DL +AH++
Sbjct: 361 TNEVNAIKWDPSG---MLLASCSDDMTLKIW---SMKQEVCIHDL----------QAHNK 404
Query: 733 PVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIA 792
++ I + T P + + + + +RLWD+ C H Y +A
Sbjct: 405 EIYTIKWSPTGP-ATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVY--SVA 461
Query: 793 FSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKL 851
FSP G++ A G+ D+ +++ S H G T + V +N ++ + DG +
Sbjct: 462 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 519
Score = 37.4 bits (85), Expect = 0.060
Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 3/116 (2%)
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGR 798
Q+KG F + + N L+ + +WD T ++ F H + +
Sbjct: 276 QHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD--VDWQNNTT 333
Query: 799 FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
FA+C D +V +G GHT+ V + ++PS LA+ + D L+++
Sbjct: 334 FASCST-DMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 388
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 52.8 bits (125), Expect = 1e-06
Identities = 87/419 (20%), Positives = 158/419 (37%), Gaps = 57/419 (13%)
Query: 454 AKEKSTKAASEQRRA--ARNVMKDQRLVFHSKVRSS------GYASAPHVTMFSPKTNIK 505
+K + E+ RA N K + ++ SS G+ S + ++P +++
Sbjct: 137 SKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLL 196
Query: 506 SEGKGSSRSR------SSCAREAYPVECAVPTKPGPQVAAAPTCTRVCCIQYSGDGQWLA 559
+ G G S +R +S V + G V P+ V + ++ +G LA
Sbjct: 197 ASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV---PSNKDVTSLDWNTNGTLLA 253
Query: 560 CGLANHLLLVF--DASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGA 617
G + ++ D +L T H G + A+ W++ ++LSA D T +W A
Sbjct: 254 TGSYDGFARIWTEDGNLAST---LGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTG 310
Query: 618 ELALLLGKDMFSKPIQSAQFYYID-----AFILLSSGPEFQLLRYHIDTCKDEIKRYKQK 672
E K F P SA +D F S+ + R C +K ++
Sbjct: 311 E-----AKQQF--PFHSAPALDVDWQNNTTFASCSTDMCIHVCRLG---CDRPVKTFQGH 360
Query: 673 SKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSR 732
+ + +G M S +D I + V + DL +AH++
Sbjct: 361 TNEVNAIKWDPSG---MLLASCSDDMTLKIW---SMKQEVCIHDL----------QAHNK 404
Query: 733 PVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIA 792
++ I + T P + + + + +RLWD+ C H Y +A
Sbjct: 405 EIYTIKWSPTGP-ATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVY--SVA 461
Query: 793 FSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKL 851
FSP G++ A G+ D+ +++ S H G T + V +N ++ + DG +
Sbjct: 462 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 519
Score = 37.4 bits (85), Expect = 0.060
Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 3/116 (2%)
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGR 798
Q+KG F + + N L+ + +WD T ++ F H + +
Sbjct: 276 QHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD--VDWQNNTT 333
Query: 799 FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
FA+C D +V +G GHT+ V + ++PS LA+ + D L+++
Sbjct: 334 FASCST-DMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 388
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 52.8 bits (125), Expect = 1e-06
Identities = 87/419 (20%), Positives = 158/419 (37%), Gaps = 57/419 (13%)
Query: 454 AKEKSTKAASEQRRA--ARNVMKDQRLVFHSKVRSS------GYASAPHVTMFSPKTNIK 505
+K + E+ RA N K + ++ SS G+ S + ++P +++
Sbjct: 188 SKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLL 247
Query: 506 SEGKGSSRSR------SSCAREAYPVECAVPTKPGPQVAAAPTCTRVCCIQYSGDGQWLA 559
+ G G S +R +S V + G V P+ V + ++ +G LA
Sbjct: 248 ASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV---PSNKDVTSLDWNTNGTLLA 304
Query: 560 CGLANHLLLVF--DASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGA 617
G + ++ D +L T H G + A+ W++ ++LSA D T +W A
Sbjct: 305 TGSYDGFARIWTEDGNLAST---LGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTG 361
Query: 618 ELALLLGKDMFSKPIQSAQFYYID-----AFILLSSGPEFQLLRYHIDTCKDEIKRYKQK 672
E K F P SA +D F S+ + R C +K ++
Sbjct: 362 E-----AKQQF--PFHSAPALDVDWQNNTTFASCSTDMCIHVCRLG---CDRPVKTFQGH 411
Query: 673 SKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSR 732
+ + +G M S +D I + V + DL +AH++
Sbjct: 412 TNEVNAIKWDPSG---MLLASCSDDMTLKIW---SMKQEVCIHDL----------QAHNK 455
Query: 733 PVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIA 792
++ I + T P + + + + +RLWD+ C H Y +A
Sbjct: 456 EIYTIKWSPTGP-ATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVY--SVA 512
Query: 793 FSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKL 851
FSP G++ A G+ D+ +++ S H G T + V +N ++ + DG +
Sbjct: 513 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 570
Score = 37.4 bits (85), Expect = 0.060
Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 3/116 (2%)
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGR 798
Q+KG F + + N L+ + +WD T ++ F H + +
Sbjct: 327 QHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD--VDWQNNTT 384
Query: 799 FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
FA+C D +V +G GHT+ V + ++PS LA+ + D L+++
Sbjct: 385 FASCST-DMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 439
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 52.8 bits (125), Expect = 1e-06
Identities = 87/419 (20%), Positives = 158/419 (37%), Gaps = 57/419 (13%)
Query: 454 AKEKSTKAASEQRRA--ARNVMKDQRLVFHSKVRSS------GYASAPHVTMFSPKTNIK 505
+K + E+ RA N K + ++ SS G+ S + ++P +++
Sbjct: 188 SKNREATVNGEENRAHSVNNHAKPMEIDGEVEIPSSKATVLRGHESEVFICAWNPVSDLL 247
Query: 506 SEGKGSSRSR------SSCAREAYPVECAVPTKPGPQVAAAPTCTRVCCIQYSGDGQWLA 559
+ G G S +R +S V + G V P+ V + ++ +G LA
Sbjct: 248 ASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDV---PSNKDVTSLDWNTNGTLLA 304
Query: 560 CGLANHLLLVF--DASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGA 617
G + ++ D +L T H G + A+ W++ ++LSA D T +W A
Sbjct: 305 TGSYDGFARIWTEDGNLAST---LGQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTG 361
Query: 618 ELALLLGKDMFSKPIQSAQFYYID-----AFILLSSGPEFQLLRYHIDTCKDEIKRYKQK 672
E K F P SA +D F S+ + R C +K ++
Sbjct: 362 E-----AKQQF--PFHSAPALDVDWQNNTTFASCSTDMCIHVCRLG---CDRPVKTFQGH 411
Query: 673 SKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSR 732
+ + +G M S +D I + V + DL +AH++
Sbjct: 412 TNEVNAIKWDPSG---MLLASCSDDMTLKIW---SMKQEVCIHDL----------QAHNK 455
Query: 733 PVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIA 792
++ I + T P + + + + +RLWD+ C H Y +A
Sbjct: 456 EIYTIKWSPTGP-ATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVY--SVA 512
Query: 793 FSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKL 851
FSP G++ A G+ D+ +++ S H G T + V +N ++ + DG +
Sbjct: 513 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRG-TGGIFEVCWNARGDKVGASASDGSV 570
Score = 37.4 bits (85), Expect = 0.060
Identities = 27/116 (23%), Positives = 49/116 (42%), Gaps = 3/116 (2%)
Query: 739 QNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGR 798
Q+KG F + + N L+ + +WD T ++ F H + +
Sbjct: 327 QHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALD--VDWQNNTT 384
Query: 799 FAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
FA+C D +V +G GHT+ V + ++PS LA+ + D L+++
Sbjct: 385 FASCST-DMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIW 439
>gi|24431950 PRP4 pre-mRNA processing factor 4 homolog [Homo
sapiens]
Length = 522
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/72 (40%), Positives = 37/72 (51%), Gaps = 2/72 (2%)
Query: 766 RLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAG 825
R+WDLRT RC EGH Y GI FSP G A G+ D V+++ + +
Sbjct: 390 RVWDLRTGRCIMFLEGHLKEIY--GINFSPNGYHIATGSGDNTCKVWDLRQRRCVYTIPA 447
Query: 826 HTDTVTGVAFNP 837
H + VTGV F P
Sbjct: 448 HQNLVTGVKFEP 459
Score = 47.8 bits (112), Expect = 4e-05
Identities = 41/146 (28%), Positives = 64/146 (43%), Gaps = 16/146 (10%)
Query: 714 VFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGM-RLWDLRT 772
V+DL G + E H + ++ G +F+ P Y++ T GD ++WDLR
Sbjct: 391 VWDLRTG-RCIMFLEGHLKEIY------GINFS---PNGYHI--ATGSGDNTCKVWDLRQ 438
Query: 773 LRCERHFEGHPTRGYPCGIAFSPC-GRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVT 831
RC H + G+ F P G F GA D A ++ + LAGH V
Sbjct: 439 RRCVYTIPAH--QNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLAGHEGKVM 496
Query: 832 GVAFNPSAPQLATATLDGKLQLFLAE 857
G+ + +AT + D +L++AE
Sbjct: 497 GLDISSDGQLIATCSYDRTFKLWMAE 522
Score = 44.7 bits (104), Expect = 4e-04
Identities = 29/97 (29%), Positives = 42/97 (43%), Gaps = 2/97 (2%)
Query: 758 TTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSS 817
TT RLWDL H EGH Y IAF G A G D V+++ +
Sbjct: 340 TTCYDRSWRLWDLEAQEEILHQEGHSMGVYD--IAFHQDGSLAGTGGLDAFGRVWDLRTG 397
Query: 818 TFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
L GH + G+ F+P+ +AT + D +++
Sbjct: 398 RCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVW 434
Score = 32.7 bits (73), Expect = 1.5
Identities = 27/105 (25%), Positives = 42/105 (40%), Gaps = 3/105 (2%)
Query: 744 SFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACG 803
S + P+ NL A G ++LW L + EGH R + + P GRF
Sbjct: 285 STVSLDPKDVNLASCAADGS-VKLWSLDSDEPVADIEGHTVR--VARVMWHPSGRFLGTT 341
Query: 804 AEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLD 848
DR ++++ + GH+ V +AF+ T LD
Sbjct: 342 CYDRSWRLWDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTGGLD 386
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 51.6 bits (122), Expect = 3e-06
Identities = 53/276 (19%), Positives = 110/276 (39%), Gaps = 36/276 (13%)
Query: 581 FSGHDGAVNAVCWSQDRRWLLSAARDGTLRMW--SARGAELALLLGKDMFSKPIQSAQFY 638
F+GH AV V +S L S +RD T+R+W + +G + ++S F
Sbjct: 19 FTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRA----HTATVRSVHF- 73
Query: 639 YIDAFILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDF 698
S G F + D+ + + K + LS ++ + +
Sbjct: 74 -------CSDGQSF------VTASDDKTVKVWATHRQKFLFSLSQH--INWVRCAKFSPD 118
Query: 699 YSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLT 758
++++A ++TV+++D ++ VH C++ G +
Sbjct: 119 -GRLIVSASDDKTVKLWD-----------KSSRECVHSYCEHGGFVTYVDFHPSGTCIAA 166
Query: 759 TAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSST 818
+ + +++WD+RT R +H++ H G++F P G + + D + ++
Sbjct: 167 AGMDNTVKVWDVRTHRLLQHYQLHSAAVN--GLSFHPSGNYLITASSDSTLKILDLMEGR 224
Query: 819 FSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
+ L GH T VAF+ + A+ D ++ ++
Sbjct: 225 LLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVW 260
Score = 32.3 bits (72), Expect = 1.9
Identities = 15/45 (33%), Positives = 27/45 (60%)
Query: 811 VYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLFL 855
V+ M + ++R GH D VT V F+PS LA+ + D +++++
Sbjct: 7 VWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWV 51
Score = 31.2 bits (69), Expect = 4.3
Identities = 22/90 (24%), Positives = 36/90 (40%), Gaps = 2/90 (2%)
Query: 765 MRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLA 824
+ +W ++ F GH C + FSP G A G+ D+ ++ S
Sbjct: 5 LMVWHMKPQSRAYRFTGHKD-AVTC-VNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFR 62
Query: 825 GHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
HT TV V F TA+ D ++++
Sbjct: 63 AHTATVRSVHFCSDGQSFVTASDDKTVKVW 92
>gi|113865883 WD repeat domain 38 [Homo sapiens]
Length = 314
Score = 51.2 bits (121), Expect = 4e-06
Identities = 28/101 (27%), Positives = 50/101 (49%), Gaps = 2/101 (1%)
Query: 754 NLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYE 813
+LF + + +RLWD+ +C R +GH ++FSP R A G D+ +++
Sbjct: 76 HLFASASCDCTVRLWDVARAKCLRVLKGHQRSVET--VSFSPDSRQLASGGWDKRVMLWD 133
Query: 814 MGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQLF 854
+ S L GH D++ F+P+ LAT + D + ++
Sbjct: 134 VQSGQMLRLLVGHRDSIQSSDFSPTVNCLATGSWDSTVHIW 174
Score = 47.8 bits (112), Expect = 4e-05
Identities = 57/268 (21%), Positives = 112/268 (41%), Gaps = 36/268 (13%)
Query: 581 FSGHDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGAELALLLGKDMFSKPIQSAQFYYI 640
F H G VN+ +S D + LL+ + DG + W R +L LG + P++ +F
Sbjct: 17 FGQHGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGH--TGPVKFCRF--- 71
Query: 641 DAFILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYS 700
P+ L + +C ++ + L +V+ S S S
Sbjct: 72 --------SPDGHL--FASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPD----S 117
Query: 701 HIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTA 760
+ + G ++ V ++D+ +G + + + ++ S ++ N T +
Sbjct: 118 RQLASGGWDKRVMLWDVQSG-----------QMLRLLVGHRDSIQSSDFSPTVNCLATGS 166
Query: 761 IGDGMRLWDLRTLR---CERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSS 817
+ +WDLR + + EGH + C + +S G A+ G+ D+ ++++ +S
Sbjct: 167 WDSTVHIWDLRMVTPAVSHQALEGH-SANISC-LCYSASGLLAS-GSWDKTIHIWKPTTS 223
Query: 818 TFSHRLAGHTDTVTGVAFNPSAPQLATA 845
+ +L GH V +AF+P LA+A
Sbjct: 224 SLLIQLKGHVTWVKSIAFSPDELWLASA 251
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/63 (36%), Positives = 32/63 (50%)
Query: 792 AFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKL 851
AFSP G+ G+ED Y +E S RL GHT V F+P A+A+ D +
Sbjct: 28 AFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDCTV 87
Query: 852 QLF 854
+L+
Sbjct: 88 RLW 90
Score = 35.8 bits (81), Expect = 0.17
Identities = 26/89 (29%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 550 QYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAARDGTL 609
++S DG A + + ++D + V GH +V V +S D R L S D +
Sbjct: 70 RFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRV 129
Query: 610 RMWSAR-GAELALLLGKDMFSKPIQSAQF 637
+W + G L LL+G IQS+ F
Sbjct: 130 MLWDVQSGQMLRLLVG---HRDSIQSSDF 155
Score = 32.3 bits (72), Expect = 1.9
Identities = 23/87 (26%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 768 WDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHT 827
W+ R+ + GH C FSP G A + D ++++ + L GH
Sbjct: 48 WETRSGQLLWRLGGHTGPVKFC--RFSPDGHLFASASCDCTVRLWDVARAKCLRVLKGHQ 105
Query: 828 DTVTGVAFNPSAPQLATATLDGKLQLF 854
+V V+F+P + QLA+ D ++ L+
Sbjct: 106 RSVETVSFSPDSRQLASGGWDKRVMLW 132
Score = 31.2 bits (69), Expect = 4.3
Identities = 17/67 (25%), Positives = 31/67 (46%), Gaps = 1/67 (1%)
Query: 546 VCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAAR 605
+ C+ YS G LA G + + ++ + + GH V ++ +S D WL SA
Sbjct: 195 ISCLCYSASGL-LASGSWDKTIHIWKPTTSSLLIQLKGHVTWVKSIAFSPDELWLASAGY 253
Query: 606 DGTLRMW 612
+++W
Sbjct: 254 SRMVKVW 260
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 50.8 bits (120), Expect = 5e-06
Identities = 41/182 (22%), Positives = 78/182 (42%), Gaps = 14/182 (7%)
Query: 673 SKSKLICRLSTTGAVDMTSLSAVNDFYSHIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSR 732
S +K C +S TG +N +++A ++ ++ V+DL A + H
Sbjct: 49 SINKPNCIMSLTGHTSPVESVRLNT-PEELIVAGSQSGSIRVWDLEAAKILRTLM-GHKA 106
Query: 733 PVHQICQNKGSSFTTQQPQAYNLFLTTAIGDGMRLWDLRTLRCERHFEGHPTRGYPCGIA 792
+ + + F Q N+ +LWD+R C + GH ++ C +
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNI----------KLWDIRRKGCVFRYRGH-SQAVRC-LR 154
Query: 793 FSPCGRFAACGAEDRHAYVYEMGSSTFSHRLAGHTDTVTGVAFNPSAPQLATATLDGKLQ 852
FSP G++ A A+D ++++ + GHT V V F+P+ LA+ + D ++
Sbjct: 155 FSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSSDRTIR 214
Query: 853 LF 854
+
Sbjct: 215 FW 216
Score = 48.9 bits (115), Expect = 2e-05
Identities = 23/67 (34%), Positives = 37/67 (55%)
Query: 546 VCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAAR 605
V C+++S DG+WLA +H + ++D + + F GH G VN V + + L S +
Sbjct: 150 VRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGSS 209
Query: 606 DGTLRMW 612
D T+R W
Sbjct: 210 DRTIRFW 216
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/117 (26%), Positives = 57/117 (48%), Gaps = 14/117 (11%)
Query: 546 VCCIQYSGDGQWLACGLANHLLLVFDASLTGTPAVFSGHDGAVNAVCWSQDRRWLLSAAR 605
+C + + G+++A G + + ++D G + GH AV + +S D +WL SAA
Sbjct: 108 ICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAAD 167
Query: 606 DGTLRMWSARGAELALLLGKDM-----FSKPIQSAQFYYIDAFILLSSGPEFQLLRY 657
D T+++W L GK M + P+ +F+ + LL+SG + +R+
Sbjct: 168 DHTVKLWD-------LTAGKMMSEFPGHTGPVNVVEFHPNE--YLLASGSSDRTIRF 215
Score = 37.0 bits (84), Expect = 0.078
Identities = 55/229 (24%), Positives = 93/229 (40%), Gaps = 34/229 (14%)
Query: 48 DGTELCIWNTKDPSHQLLILRGHHQPITAMAFGNKVNPLLICSASLDYVIMWNLDECREK 107
D + +W+ P+ ++ L GH P+ ++ N L++ + + +W+L+ K
Sbjct: 41 DDCRVNLWSINKPNC-IMSLTGHTSPVESVRL-NTPEELIVAGSQSGSIRVWDLEAA--K 96
Query: 108 VLQGLVPRGTVMGSLLGKVLCLQLSLDDHVVA--VCAGNK---IFMLDIEQRFSVTYIER 162
+L+ T+MG +C SLD H V +G++ I + DI ++ V
Sbjct: 97 ILR------TLMGHKAN--IC---SLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRG 145
Query: 163 PD--VNNRHKVPPPTFLHTFSQTQAVR----------AELQGHLGPVTAVEFCPWRAGTL 210
V P +L + + V+ +E GH GPV VEF P L
Sbjct: 146 HSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP-NEYLL 204
Query: 211 ISASEDRGFKVWDHCTGSLIYSSSVLSAYPLLSLFIDAESRQLVTGCAD 259
S S DR + WD + S P+ S+ + + L +GC D
Sbjct: 205 ASGSSDRTIRFWD-LEKFQVVSCIEGEPGPVRSVLFNPDGCCLYSGCQD 252
Score = 36.6 bits (83), Expect = 0.10
Identities = 50/226 (22%), Positives = 90/226 (39%), Gaps = 34/226 (15%)
Query: 582 SGHDGAVNAVCWSQDRRWLLSAARDGTLRMWSARGAE-LALLLGKDMFSKPIQSAQFYYI 640
+GH V +V + +++ ++ G++R+W A+ L L+G I S F+
Sbjct: 60 TGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMG---HKANICSLDFHPY 116
Query: 641 DAFILLSSGPEFQLLRYHIDTCKDEIKRYKQKSKSKLICRLSTTGAVDMTSLSAVNDFYS 700
F+ +SG + ++ K + RY+ S++ R S G
Sbjct: 117 GEFV--ASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDG--------------- 159
Query: 701 HIVLAAGRNRTVEVFDLNAGCSAAVIAEAHSRPVHQICQNKGSSFTTQQPQAYNLFLTTA 760
+ +A + TV+++DL AG + H+ PV+ + P Y L + +
Sbjct: 160 KWLASAADDHTVKLWDLTAGKMMSEF-PGHTGPVNVV---------EFHPNEY-LLASGS 208
Query: 761 IGDGMRLWDLRTLRCERHFEGHPTRGYPCGIAFSPCGRFAACGAED 806
+R WDL + EG P G + F+P G G +D
Sbjct: 209 SDRTIRFWDLEKFQVVSCIEGEP--GPVRSVLFNPDGCCLYSGCQD 252
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.134 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,906,783
Number of Sequences: 37866
Number of extensions: 1464328
Number of successful extensions: 5420
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 3892
Number of HSP's gapped (non-prelim): 1423
length of query: 857
length of database: 18,247,518
effective HSP length: 111
effective length of query: 746
effective length of database: 14,044,392
effective search space: 10477116432
effective search space used: 10477116432
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.