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Search of human proteins with 55926200
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55926200 potassium channel tetramerisation domain containing
16 [Homo sapiens]
(428 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55926200 potassium channel tetramerisation domain containing ... 884 0.0
gi|38198663 potassium channel tetramerisation domain containing ... 495 e-140
gi|19923973 potassium channel tetramerisation domain containing ... 315 7e-86
gi|71143104 potassium channel tetramerisation domain containing ... 92 7e-19
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens] 82 9e-16
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens] 82 9e-16
gi|189571693 potassium channel tetramerisation domain containing... 80 4e-15
gi|189571691 potassium channel tetramerisation domain containing... 80 4e-15
gi|142356950 potassium channel tetramerisation domain containing... 71 2e-12
gi|146198864 potassium channel tetramerisation domain containing... 71 2e-12
gi|218505694 potassium channel tetramerisation domain containing... 70 5e-12
gi|209969708 potassium channel tetramerisation domain containing... 70 5e-12
gi|40217617 potassium channel tetramerisation domain containing ... 70 5e-12
gi|194018443 potassium channel tetramerisation domain containing... 69 1e-11
gi|194018441 potassium channel tetramerisation domain containing... 69 1e-11
gi|194018439 potassium channel tetramerisation domain containing... 69 1e-11
gi|9506651 potassium channel tetramerisation domain containing 5... 65 9e-11
gi|45387953 potassium channel tetramerization domain containing ... 64 3e-10
gi|23308551 potassium channel tetramerisation domain containing ... 64 3e-10
gi|53829365 potassium channel tetramerisation domain containing ... 58 1e-08
gi|46255026 potassium channel tetramerisation domain containing ... 56 5e-08
gi|13994353 potassium channel tetramerisation domain containing ... 55 9e-08
gi|30578412 potassium channel tetramerisation domain containing ... 55 9e-08
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo... 54 3e-07
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens] 54 3e-07
gi|169234778 potassium channel tetramerisation domain containing... 53 6e-07
gi|39753959 potassium channel tetramerisation domain containing ... 53 6e-07
gi|51036594 potassium channel tetramerisation domain containing ... 49 7e-06
gi|169184031 PREDICTED: similar to potassium channel tetramerisa... 48 1e-05
gi|169179790 PREDICTED: similar to potassium channel tetramerisa... 48 1e-05
>gi|55926200 potassium channel tetramerisation domain containing 16
[Homo sapiens]
Length = 428
Score = 884 bits (2284), Expect = 0.0
Identities = 428/428 (100%), Positives = 428/428 (100%)
Query: 1 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 60
MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD
Sbjct: 1 MALSGNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRD 60
Query: 61 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 120
TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK
Sbjct: 61 TANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 120
Query: 121 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 180
LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG
Sbjct: 121 LLTPDEIKQSPDEFCHSDFEDASQGSDTRICPPSSLLPADRKWGFITVGYRGSCTLGREG 180
Query: 181 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 240
QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML
Sbjct: 181 QADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFKHLERAFDML 240
Query: 241 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE 300
SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE
Sbjct: 241 SECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSRWSPSHCDCCCKNGKGDKE 300
Query: 301 GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR 360
GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR
Sbjct: 301 GESGTSCNDLSTSSCDSQSEASSPQETVICGPVTRQTNIQTLDRPIKKGPVQLIQQSEMR 360
Query: 361 RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS 420
RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS
Sbjct: 361 RKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKIPDRFPERKHPWQS 420
Query: 421 ELLRKYHL 428
ELLRKYHL
Sbjct: 421 ELLRKYHL 428
>gi|38198663 potassium channel tetramerisation domain containing 8
[Homo sapiens]
Length = 473
Score = 495 bits (1274), Expect = e-140
Identities = 270/441 (61%), Positives = 317/441 (71%), Gaps = 30/441 (6%)
Query: 16 GSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTAN-----DLAKDSK 70
G P+ FPEVVELNVGGQVY T+HSTL+S+P S L MFSP +L +DS+
Sbjct: 35 GPCAPSPFPEVVELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSR 94
Query: 71 GRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQS 130
RFFIDRDGFLFRY+LDYLRD+Q+ LP+HFPEK RL REAEYFQL DLVKLL+P KQ+
Sbjct: 95 ARFFIDRDGFLFRYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQN 154
Query: 131 P--DEFCHSDFED-ASQGSDTRIC--PPSSLLPA--------------DRKWGFITVGYR 171
DE C SD ED SQGS + ++ +P+ D++ GF+T+GYR
Sbjct: 155 SLNDEGCQSDLEDNVSQGSSDALLLRGAAAAVPSGPGAHGGGGGGGAQDKRSGFLTLGYR 214
Query: 172 GSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAPERYTSRFYLKFK 231
GS T R+ QADAKFRRV RI+VCGRI+LAKEVFG+TLNESRDPDR PE+YTSRFYLKF
Sbjct: 215 GSYTTVRDNQADAKFRRVARIMVCGRIALAKEVFGDTLNESRDPDRQPEKYTSRFYLKFT 274
Query: 232 HLERAFDMLSECGFHMVACNSSVTASFINQYTDDKIWSSYTEYVFYREPSR-WSPSHCDC 290
+LE+AFD LSE GFHMVACNSS TA+F+NQY DDKIWSSYTEY+F+R P + SP
Sbjct: 275 YLEQAFDRLSEAGFHMVACNSSGTAAFVNQYRDDKIWSSYTEYIFFRPPQKIVSPKQEHE 334
Query: 291 CCKNGK-GDKEGESGTSCNDLSTSSCDSQSEASSPQETVICG--PVTRQTNIQTLDRPIK 347
K+ K DK ESGTSCN+LSTSSCDS SEAS+PQ+ Q N TLDRP K
Sbjct: 335 DRKHDKVTDKGSESGTSCNELSTSSCDSHSEASTPQDNPSSAQQATAHQPNTLTLDRPSK 394
Query: 348 KGPVQLIQQSEMRRKSDLLRTLTSGSRESNMSSKKKAVKEKLSIEEELEKCIQDFLKIKI 407
K PVQ I + RR S+L +TL S SRE+N+S KK V EKLS+EEE++KCIQDF KI I
Sbjct: 395 KAPVQWIPPPDKRRNSELFQTLISKSRETNLSKKK--VCEKLSVEEEMKKCIQDFKKIHI 452
Query: 408 PDRFPERKHPWQSELLRKYHL 428
PD FPERK WQSELL+KY L
Sbjct: 453 PDYFPERKRQWQSELLQKYGL 473
>gi|19923973 potassium channel tetramerisation domain containing 12
[Homo sapiens]
Length = 325
Score = 315 bits (806), Expect = 7e-86
Identities = 167/302 (55%), Positives = 207/302 (68%), Gaps = 41/302 (13%)
Query: 17 SAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFID 76
SA P FP++VELNVGGQVY TR T++S+P SLLW+MF+ ++ +LA+DSKGRFF+D
Sbjct: 26 SAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQP--QELARDSKGRFFLD 83
Query: 77 RDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL-TPDEIKQSP---- 131
RDGFLFRYILDYLRD Q+VLPD+FPE+ RL+REAEYF+LP+LV+ L P + P
Sbjct: 84 RDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVRRLGAPQQPGPGPPPSR 143
Query: 132 ----------DEFCHSDFEDASQ----------------------GSDTRICPPSSLLPA 159
DE + + Q G+ + PS L
Sbjct: 144 RGVHKEGSLGDELLPLGYSEPEQQEGASAGAPSPTLELASRSPSGGAAGPLLTPSQSLDG 203
Query: 160 DRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVFGETLNESRDPDRAP 219
R+ G+IT+GYRGS T+GR+ QADAKFRRV RI VCG+ SLAKEVFG+TLNESRDPDR P
Sbjct: 204 SRRSGYITIGYRGSYTIGRDAQADAKFRRVARITVCGKTSLAKEVFGDTLNESRDPDRPP 263
Query: 220 ERYTSRFYLKFKHLERAFDMLSECGFHMVACNSSVTASFIN--QYTDDKIWSSYTEYVFY 277
ERYTSR+YLKF LE+AFD LSE GFHMVAC+S+ T +F + ++DKIW+SYTEYVF
Sbjct: 264 ERYTSRYYLKFNFLEQAFDKLSESGFHMVACSSTGTCAFASSTDQSEDKIWTSYTEYVFC 323
Query: 278 RE 279
RE
Sbjct: 324 RE 325
>gi|71143104 potassium channel tetramerisation domain containing 21
[Homo sapiens]
Length = 260
Score = 92.4 bits (228), Expect = 7e-19
Identities = 49/107 (45%), Positives = 70/107 (65%), Gaps = 4/107 (3%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
+ LNVGG++Y T +TL S P S+L MFS K T +DS+G FIDRDG +FRYIL
Sbjct: 5 ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMPTK----RDSQGNCFIDRDGKVFRYIL 60
Query: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDE 133
++LR + LP+ F E G L+REA+++Q+ L++ L E++ S E
Sbjct: 61 NFLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEKEVELSKAE 107
>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
Length = 229
Score = 82.0 bits (201), Expect = 9e-16
Identities = 47/110 (42%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 22 SFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFL 81
S E+V LNVGG+++ TR ST+ P S L +M D + K G+ F+DRDG L
Sbjct: 2 SSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----DGRDQEFKMVGGQIFVDRDGDL 57
Query: 82 FRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSP 131
F +ILD+LR Q++LP F + RL+REA +++L LV LL P ++ P
Sbjct: 58 FSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRP 107
>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
Length = 272
Score = 82.0 bits (201), Expect = 9e-16
Identities = 47/110 (42%), Positives = 67/110 (60%), Gaps = 4/110 (3%)
Query: 22 SFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFL 81
S E+V LNVGG+++ TR ST+ P S L +M D + K G+ F+DRDG L
Sbjct: 2 SSQELVTLNVGGKIFTTRFSTIKQFPASRLARML----DGRDQEFKMVGGQIFVDRDGDL 57
Query: 82 FRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSP 131
F +ILD+LR Q++LP F + RL+REA +++L LV LL P ++ P
Sbjct: 58 FSFILDFLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLLNPYLLQPRP 107
>gi|189571693 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 80.1 bits (196), Expect = 4e-15
Identities = 48/123 (39%), Positives = 70/123 (56%), Gaps = 9/123 (7%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
V LNVGG +Y T +TL P S+L MF TA +D +G +FIDRDG LFRY+L
Sbjct: 14 VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTA----RDPQGNYFIDRDGPLFRYVL 69
Query: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGS 146
++LR ++ LP F E L++EA+++Q+ L++ L + D FE+ + S
Sbjct: 70 NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMD-----TFEEVVELS 124
Query: 147 DTR 149
TR
Sbjct: 125 STR 127
>gi|189571691 potassium channel tetramerisation domain containing 6
[Homo sapiens]
Length = 237
Score = 80.1 bits (196), Expect = 4e-15
Identities = 48/123 (39%), Positives = 70/123 (56%), Gaps = 9/123 (7%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
V LNVGG +Y T +TL P S+L MF TA +D +G +FIDRDG LFRY+L
Sbjct: 14 VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFPTA----RDPQGNYFIDRDGPLFRYVL 69
Query: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQGS 146
++LR ++ LP F E L++EA+++Q+ L++ L + D FE+ + S
Sbjct: 70 NFLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLNDPKPLYPMD-----TFEEVVELS 124
Query: 147 DTR 149
TR
Sbjct: 125 STR 127
>gi|142356950 potassium channel tetramerisation domain containing 14
[Homo sapiens]
Length = 255
Score = 71.2 bits (173), Expect = 2e-12
Identities = 46/97 (47%), Positives = 58/97 (59%), Gaps = 8/97 (8%)
Query: 26 VVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYI 85
VVELNVGG+ + T TL P S L +MFS + D ++GRFFIDR FR I
Sbjct: 34 VVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTD----AEGRFFIDRPSTYFRPI 89
Query: 86 LDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
LDYLR QV H PE + REA+++++ LVKLL
Sbjct: 90 LDYLRTGQVP-TQHIPE---VYREAQFYEIKPLVKLL 122
>gi|146198864 potassium channel tetramerisation domain containing 4
[Homo sapiens]
Length = 259
Score = 70.9 bits (172), Expect = 2e-12
Identities = 38/95 (40%), Positives = 59/95 (62%), Gaps = 4/95 (4%)
Query: 26 VVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYI 85
++ LNVGG +Y T+ TL P + L + + K D + G +FIDRDG LFR++
Sbjct: 34 LMTLNVGGYLYITQKQTLTKYPDTFLEGIVNGKILCPFD----ADGHYFIDRDGLLFRHV 89
Query: 86 LDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 120
L++LR+ +++LP+ F E L +EAE+FQL L +
Sbjct: 90 LNFLRNGELLLPEGFRENQLLAQEAEFFQLKGLAE 124
>gi|218505694 potassium channel tetramerisation domain containing 1
isoform b [Homo sapiens]
Length = 865
Score = 69.7 bits (169), Expect = 5e-12
Identities = 70/245 (28%), Positives = 109/245 (44%), Gaps = 52/245 (21%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDS-KGRFFIDRDGFLFRYI 85
V ++VGG +Y + +TL P S + ++F D + DS K +FIDRDG +FRYI
Sbjct: 640 VHIDVGGHMYTSSLATLTKYPESRIGRLF----DGTEPIVLDSLKQHYFIDRDGQMFRYI 695
Query: 86 LDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQG 145
L++LR ++++PD F + L EA+YFQL + LL + KQ D G
Sbjct: 696 LNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM--LLEMERWKQ-----------DRETG 742
Query: 146 SDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVF 205
+R C + R + LG RI + G SL +EVF
Sbjct: 743 RFSRPCE--------------CLVVRVAPDLGE------------RITLSGDKSLIEEVF 776
Query: 206 GETLNESRDPDRAPERYTSRFYLKFK-----HLE--RAFDMLSECGFHMV-ACNSSVTAS 257
E + + A + S ++F HL + + L + GF +V +C V +S
Sbjct: 777 PEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSS 836
Query: 258 FINQY 262
++Y
Sbjct: 837 QFSEY 841
>gi|209969708 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 69.7 bits (169), Expect = 5e-12
Identities = 70/245 (28%), Positives = 109/245 (44%), Gaps = 52/245 (21%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDS-KGRFFIDRDGFLFRYI 85
V ++VGG +Y + +TL P S + ++F D + DS K +FIDRDG +FRYI
Sbjct: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLF----DGTEPIVLDSLKQHYFIDRDGQMFRYI 87
Query: 86 LDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQG 145
L++LR ++++PD F + L EA+YFQL + LL + KQ D G
Sbjct: 88 LNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM--LLEMERWKQ-----------DRETG 134
Query: 146 SDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVF 205
+R C + R + LG RI + G SL +EVF
Sbjct: 135 RFSRPCE--------------CLVVRVAPDLGE------------RITLSGDKSLIEEVF 168
Query: 206 GETLNESRDPDRAPERYTSRFYLKFK-----HLE--RAFDMLSECGFHMV-ACNSSVTAS 257
E + + A + S ++F HL + + L + GF +V +C V +S
Sbjct: 169 PEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSS 228
Query: 258 FINQY 262
++Y
Sbjct: 229 QFSEY 233
>gi|40217617 potassium channel tetramerisation domain containing 1
isoform a [Homo sapiens]
Length = 257
Score = 69.7 bits (169), Expect = 5e-12
Identities = 70/245 (28%), Positives = 109/245 (44%), Gaps = 52/245 (21%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDS-KGRFFIDRDGFLFRYI 85
V ++VGG +Y + +TL P S + ++F D + DS K +FIDRDG +FRYI
Sbjct: 32 VHIDVGGHMYTSSLATLTKYPESRIGRLF----DGTEPIVLDSLKQHYFIDRDGQMFRYI 87
Query: 86 LDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQSPDEFCHSDFEDASQG 145
L++LR ++++PD F + L EA+YFQL + LL + KQ D G
Sbjct: 88 LNFLRTSKLLIPDDFKDYTLLYEEAKYFQLQPM--LLEMERWKQ-----------DRETG 134
Query: 146 SDTRICPPSSLLPADRKWGFITVGYRGSCTLGREGQADAKFRRVPRILVCGRISLAKEVF 205
+R C + R + LG RI + G SL +EVF
Sbjct: 135 RFSRPCE--------------CLVVRVAPDLGE------------RITLSGDKSLIEEVF 168
Query: 206 GETLNESRDPDRAPERYTSRFYLKFK-----HLE--RAFDMLSECGFHMV-ACNSSVTAS 257
E + + A + S ++F HL + + L + GF +V +C V +S
Sbjct: 169 PEIGDVMCNSVNAGWNHDSTHVIRFPLNGYCHLNSVQVLERLQQRGFEIVGSCGGGVDSS 228
Query: 258 FINQY 262
++Y
Sbjct: 229 QFSEY 233
>gi|194018443 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 68.6 bits (166), Expect = 1e-11
Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
V ++VGG +Y + +TL P S + ++F+ D K +FIDRDG +FRY+L
Sbjct: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQ---HYFIDRDGEIFRYVL 114
Query: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
+LR +++LPD F + L EA Y+QL +V+ L
Sbjct: 115 SFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL 150
>gi|194018441 potassium channel tetramerisation domain containing 15
isoform 2 [Homo sapiens]
Length = 283
Score = 68.6 bits (166), Expect = 1e-11
Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
V ++VGG +Y + +TL P S + ++F+ D K +FIDRDG +FRY+L
Sbjct: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQ---HYFIDRDGEIFRYVL 114
Query: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
+LR +++LPD F + L EA Y+QL +V+ L
Sbjct: 115 SFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL 150
>gi|194018439 potassium channel tetramerisation domain containing 15
isoform 1 [Homo sapiens]
Length = 234
Score = 68.6 bits (166), Expect = 1e-11
Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 3/96 (3%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
V ++VGG +Y + +TL P S + ++F+ D K +FIDRDG +FRY+L
Sbjct: 58 VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQ---HYFIDRDGEIFRYVL 114
Query: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
+LR +++LPD F + L EA Y+QL +V+ L
Sbjct: 115 SFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVREL 150
>gi|9506651 potassium channel tetramerisation domain containing 5
[Homo sapiens]
Length = 234
Score = 65.5 bits (158), Expect = 9e-11
Identities = 40/110 (36%), Positives = 62/110 (56%), Gaps = 4/110 (3%)
Query: 20 PNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDG 79
P S + V LNVGG + T TL P S L+++ D +D KD G + IDRD
Sbjct: 39 PGSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLCQADPDLDSD--KDETGAYLIDRDP 96
Query: 80 FLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLLTPDEIKQ 129
F +L+YLR ++V+ E+G L+ EAE++ + L+KL+ D+I++
Sbjct: 97 TYFGPVLNYLRHGKLVINKDLAEEGVLE-EAEFYNITSLIKLV-KDKIRE 144
>gi|45387953 potassium channel tetramerization domain containing 18
[Homo sapiens]
Length = 426
Score = 63.9 bits (154), Expect = 3e-10
Identities = 44/136 (32%), Positives = 65/136 (47%), Gaps = 18/136 (13%)
Query: 15 QGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFF 74
+G +V+ LNVGG +Y R +L S+L MFS + L D G
Sbjct: 2 EGHKAEEEVLDVLRLNVGGCIYTARRESLCRFKDSMLASMFSGRFP----LKTDESGACV 57
Query: 75 IDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLP-------------DLVKL 121
IDRDG LF+Y+LDYL +V +P + L+ EA+YF +P + L
Sbjct: 58 IDRDGRLFKYLLDYLHG-EVQIPTDEQTRIALQEEADYFGIPYPYSLSDHLANEMETYSL 116
Query: 122 LTPDEIKQSPDEFCHS 137
+ E+K++ +FC S
Sbjct: 117 RSNIELKKALTDFCDS 132
>gi|23308551 potassium channel tetramerisation domain containing 7
[Homo sapiens]
Length = 289
Score = 63.9 bits (154), Expect = 3e-10
Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 13/107 (12%)
Query: 19 VPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRD 78
+P FPEVV LN+GG + TR STL ++L MFS + + + DS+GR+FIDRD
Sbjct: 45 LPQEFPEVVPLNIGGAHFTTRLSTLRCYEDTMLAAMFSGR----HYIPTDSEGRYFIDRD 100
Query: 79 GFLFRYILDYLRDRQVVLPDHFPEKGRLK---REAEYFQLPDLVKLL 122
G F +L++LR + P + R++ +EA+Y+ + L++ L
Sbjct: 101 GTHFGDVLNFLRSGDL------PPRERVRAVYKEAQYYAIGPLLEQL 141
>gi|53829365 potassium channel tetramerisation domain containing 2
[Homo sapiens]
Length = 263
Score = 58.2 bits (139), Expect = 1e-08
Identities = 36/96 (37%), Positives = 53/96 (55%), Gaps = 2/96 (2%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
V LNVGG + T TL P S L ++ + D D KD G + IDRD F IL
Sbjct: 74 VRLNVGGTYFVTTRQTLGREPKSFLCRLCC-QEDPELDSDKDETGAYLIDRDPTYFGPIL 132
Query: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
+YLR ++++ E+G L+ EAE++ + LV+L+
Sbjct: 133 NYLRHGKLIITKELAEEGVLE-EAEFYNIASLVRLV 167
>gi|46255026 potassium channel tetramerisation domain containing 3
[Homo sapiens]
Length = 815
Score = 56.2 bits (134), Expect = 5e-08
Identities = 42/127 (33%), Positives = 65/127 (51%), Gaps = 13/127 (10%)
Query: 5 GNCSRYYPREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTAND 64
G+C + GS E+V+LNVGG + T TL+ IP S + S + T
Sbjct: 4 GHCGSFPAAAAGSG------EIVQLNVGGTRFSTSRQTLMWIPDSFFSSLLSGRIST--- 54
Query: 65 LAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLV-KLLT 123
+D G FIDRD F IL++LR +++ L L+ EAE++ + LV +LL
Sbjct: 55 -LRDETGAIFIDRDPAAFAPILNFLRTKELDL--RGVSINVLRHEAEFYGITPLVRRLLL 111
Query: 124 PDEIKQS 130
+E+++S
Sbjct: 112 CEELERS 118
>gi|13994353 potassium channel tetramerisation domain containing 10
[Homo sapiens]
Length = 313
Score = 55.5 bits (132), Expect = 9e-08
Identities = 38/94 (40%), Positives = 52/94 (55%), Gaps = 5/94 (5%)
Query: 27 VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86
V+LNVGG +Y+T TL ++L MFS + + D S+G IDR G F IL
Sbjct: 34 VKLNVGGALYYTTMQTLTK-QDTMLKAMFSGRMEVLTD----SEGWILIDRCGKHFGTIL 88
Query: 87 DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 120
+YLRD V LP+ E L EA+Y+ + LV+
Sbjct: 89 NYLRDGAVPLPESRREIEELLAEAKYYLVQGLVE 122
>gi|30578412 potassium channel tetramerisation domain containing 13
[Homo sapiens]
Length = 329
Score = 55.5 bits (132), Expect = 9e-08
Identities = 39/101 (38%), Positives = 54/101 (53%), Gaps = 7/101 (6%)
Query: 20 PNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDG 79
PNS + V+LNVGG +++T TL ++L MFS + + D G IDR G
Sbjct: 38 PNS--KYVKLNVGGSLHYTTLRTLTG-QDTMLKAMFSGRVEVLTDAG----GWVLIDRSG 90
Query: 80 FLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVK 120
F IL+YLRD V LP+ E G L EA Y+ + L++
Sbjct: 91 RHFGTILNYLRDGSVPLPESTRELGELLGEARYYLVQGLIE 131
>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
sapiens]
Length = 316
Score = 53.9 bits (128), Expect = 3e-07
Identities = 38/113 (33%), Positives = 56/113 (49%), Gaps = 20/113 (17%)
Query: 15 QGSAVPNSFPEVVELNVGGQVYFT------RHSTLISIPHSLLWKMFSPKRDTANDLAKD 68
+G + N + V+LNVGG +Y+T RH T++ MFS + + D
Sbjct: 21 KGGGLGNKY---VQLNVGGSLYYTTVRALTRHDTMLKA-------MFSGRMEVLTD---- 66
Query: 69 SKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKL 121
+G IDR G F IL+YLRD + LP + E L EA+Y+ + LV +
Sbjct: 67 KEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNM 119
>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
Length = 707
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/106 (36%), Positives = 54/106 (50%), Gaps = 8/106 (7%)
Query: 19 VPNSFP--EVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFID 76
VP+ P EV+ LNVGG+ + T TL IP S + S + T KD G FID
Sbjct: 11 VPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRIST----LKDETGAIFID 66
Query: 77 RDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
RD +F IL++LR ++ L L EA+++ L LV+ L
Sbjct: 67 RDPTVFAPILNFLRTKE--LDPRGVHGSSLLHEAQFYGLTPLVRRL 110
>gi|169234778 potassium channel tetramerisation domain containing 17
[Homo sapiens]
Length = 297
Score = 52.8 bits (125), Expect = 6e-07
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 4/111 (3%)
Query: 12 PREQGSAVPNSFPEVVELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKG 71
P G + + V LNVGG V+ T TL S L ++ + ++ +D G
Sbjct: 18 PAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGEELQSD---RDETG 74
Query: 72 RFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
+ IDRD F IL++LR ++VL E+G L+ EAE++ + L++++
Sbjct: 75 AYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLE-EAEFYNIGPLIRII 124
>gi|39753959 potassium channel tetramerisation domain containing 9
[Homo sapiens]
Length = 389
Score = 52.8 bits (125), Expect = 6e-07
Identities = 37/95 (38%), Positives = 53/95 (55%), Gaps = 4/95 (4%)
Query: 29 LNVGGQVYFTRHSTLISI-PHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILD 87
LNVGG+ + T STL++ P S+L MF K N +D +G F IDR F IL+
Sbjct: 93 LNVGGRYFTTTRSTLVNKEPDSMLAHMFKDKGVWGNK--QDHRGAFLIDRSPEYFEPILN 150
Query: 88 YLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
YLR Q+++ D G L+ EA +F + L++ L
Sbjct: 151 YLRHGQLIVNDGINLLGVLE-EARFFGIDSLIEHL 184
>gi|51036594 potassium channel tetramerisation domain containing 11
[Homo sapiens]
Length = 232
Score = 49.3 bits (116), Expect = 7e-06
Identities = 28/80 (35%), Positives = 43/80 (53%)
Query: 50 LLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILDYLRDRQVVLPDHFPEKGRLKRE 109
+L MF +L G +FIDRDG FR+IL++LR ++ LP + E L+ E
Sbjct: 1 MLGAMFRAGTPMPPNLNSQGGGHYFIDRDGKAFRHILNFLRLGRLDLPRGYGETALLRAE 60
Query: 110 AEYFQLPDLVKLLTPDEIKQ 129
A+++Q+ L+ L E Q
Sbjct: 61 ADFYQIRPLLDALRELEASQ 80
>gi|169184031 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 48.1 bits (113), Expect = 1e-05
Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 4/95 (4%)
Query: 29 LNVGGQVYFTRHSTLISI-PHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILD 87
L+VGGQ + T STL++ P +L MF K N +D +G F ID+ F IL+
Sbjct: 93 LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNK--QDHRGAFLIDQSPEYFEPILN 150
Query: 88 YLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
YLR Q+++ D G L+ EA +F + L++ L
Sbjct: 151 YLRHGQLIVNDGIDLLGVLE-EARFFGIDSLIEHL 184
>gi|169179790 PREDICTED: similar to potassium channel
tetramerisation domain containing 9 [Homo sapiens]
Length = 261
Score = 48.1 bits (113), Expect = 1e-05
Identities = 35/95 (36%), Positives = 52/95 (54%), Gaps = 4/95 (4%)
Query: 29 LNVGGQVYFTRHSTLISI-PHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYILD 87
L+VGGQ + T STL++ P +L MF K N +D +G F ID+ F IL+
Sbjct: 93 LHVGGQYFTTTWSTLVNKEPDIMLAHMFKDKGVWGNK--QDHRGAFLIDQSPEYFEPILN 150
Query: 88 YLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122
YLR Q+++ D G L+ EA +F + L++ L
Sbjct: 151 YLRHGQLIVNDGIDLLGVLE-EARFFGIDSLIEHL 184
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,513,995
Number of Sequences: 37866
Number of extensions: 817290
Number of successful extensions: 2678
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 57
Number of HSP's that attempted gapping in prelim test: 2579
Number of HSP's gapped (non-prelim): 112
length of query: 428
length of database: 18,247,518
effective HSP length: 105
effective length of query: 323
effective length of database: 14,271,588
effective search space: 4609722924
effective search space used: 4609722924
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.