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Search of human proteins with 55770882
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55770882 keratin 37 [Homo sapiens]
(449 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55770882 keratin 37 [Homo sapiens] 905 0.0
gi|15431318 keratin 38 [Homo sapiens] 820 0.0
gi|14917115 keratin 31 [Homo sapiens] 476 e-134
gi|14917117 keratin 33A [Homo sapiens] 470 e-132
gi|14917119 keratin 34 [Homo sapiens] 466 e-131
gi|10337581 type I hair keratin 3B [Homo sapiens] 465 e-131
gi|116488398 keratin 32 [Homo sapiens] 454 e-127
gi|4504927 keratin 36 [Homo sapiens] 449 e-126
gi|94538345 keratin 35 [Homo sapiens] 442 e-124
gi|125490370 type I hair keratin KA36 [Homo sapiens] 404 e-113
gi|148277620 type I hair keratin KA35 [Homo sapiens] 385 e-107
gi|4557701 keratin 17 [Homo sapiens] 323 3e-88
gi|24430190 keratin 15 [Homo sapiens] 317 2e-86
gi|15431310 keratin 14 [Homo sapiens] 316 2e-86
gi|131412225 keratin 13 isoform a [Homo sapiens] 313 3e-85
gi|24430192 keratin 16 [Homo sapiens] 311 6e-85
gi|131412228 keratin 13 isoform b [Homo sapiens] 309 3e-84
gi|24234699 keratin 19 [Homo sapiens] 305 7e-83
gi|195972866 keratin 10 [Homo sapiens] 292 5e-79
gi|4557699 keratin 12 [Homo sapiens] 281 8e-76
gi|27894337 keratin 20 [Homo sapiens] 278 9e-75
gi|114431246 keratin 25D [Homo sapiens] 265 8e-71
gi|153945736 keratin 27 [Homo sapiens] 256 2e-68
gi|192807292 keratin 24 [Homo sapiens] 254 9e-68
gi|31559829 keratin 25 [Homo sapiens] 249 5e-66
gi|40354195 keratin 18 [Homo sapiens] 249 5e-66
gi|4557888 keratin 18 [Homo sapiens] 249 5e-66
gi|27894339 keratin 23 [Homo sapiens] 246 3e-65
gi|31559815 keratin 26 [Homo sapiens] 242 4e-64
gi|55956899 keratin 9 [Homo sapiens] 239 3e-63
>gi|55770882 keratin 37 [Homo sapiens]
Length = 449
Score = 905 bits (2339), Expect = 0.0
Identities = 449/449 (100%), Positives = 449/449 (100%)
Query: 1 MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGST 60
MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGST
Sbjct: 1 MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGST 60
Query: 61 PLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLE 120
PLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLE
Sbjct: 61 PLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLE 120
Query: 121 KVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQID 180
KVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQID
Sbjct: 121 KVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQID 180
Query: 181 NAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
NAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS
Sbjct: 181 NAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
Query: 241 NHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSE 300
NHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSE
Sbjct: 241 NHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSE 300
Query: 301 GISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELA 360
GISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELA
Sbjct: 301 GISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELA 360
Query: 361 QMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPC 420
QMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPC
Sbjct: 361 QMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPC 420
Query: 421 STPASCTSCPSCGPVTGGSPSGHGASMGR 449
STPASCTSCPSCGPVTGGSPSGHGASMGR
Sbjct: 421 STPASCTSCPSCGPVTGGSPSGHGASMGR 449
>gi|15431318 keratin 38 [Homo sapiens]
Length = 456
Score = 820 bits (2119), Expect = 0.0
Identities = 412/453 (90%), Positives = 423/453 (93%), Gaps = 5/453 (1%)
Query: 1 MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGST 60
MTS YS+SSCPLGCTMAPGARNV VSPID+GCQP AEAN A MCLLANVAHANRVRVGST
Sbjct: 1 MTSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANIAPMCLLANVAHANRVRVGST 60
Query: 61 PLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLE 120
PLGRPSLCLPPT HTACPLPGTCHIPGNIGICGAYG+NTLNGHEKETM+FLNDRLANYLE
Sbjct: 61 PLGRPSLCLPPTCHTACPLPGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANYLE 120
Query: 121 KVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQID 180
KVRQLEQENAELE TLLERSKCHESTVCPDYQSYF TIEELQQKILCSKAENARLIVQID
Sbjct: 121 KVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHTIEELQQKILCSKAENARLIVQID 180
Query: 181 NAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
NAKLAADDFRIKLESERSL QLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS
Sbjct: 181 NAKLAADDFRIKLESERSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
Query: 241 NHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSE 300
NHEQEVKILRSQLGEK RIELDIEPTIDLNRVLGEMRAQYEAM+ETN QDVEQWFQAQSE
Sbjct: 241 NHEQEVKILRSQLGEKLRIELDIEPTIDLNRVLGEMRAQYEAMLETNRQDVEQWFQAQSE 300
Query: 301 GISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELA 360
GISLQ MSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDR+GTELA
Sbjct: 301 GISLQDMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRFGTELA 360
Query: 361 QMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPC 420
QMQSLISN+EEQLSEIRADLERQNQEYQVLLDVK RLENEIATYRNLLESEDCKLPCNPC
Sbjct: 361 QMQSLISNVEEQLSEIRADLERQNQEYQVLLDVKTRLENEIATYRNLLESEDCKLPCNPC 420
Query: 421 STPASCTSC-----PSCGPVTGGSPSGHGASMG 448
ST SC + PSCGP T P+ ++ G
Sbjct: 421 STSPSCVTAPCAPRPSCGPCTTCGPTCGASTTG 453
>gi|14917115 keratin 31 [Homo sapiens]
Length = 416
Score = 476 bits (1226), Expect = e-134
Identities = 242/391 (61%), Positives = 301/391 (76%), Gaps = 25/391 (6%)
Query: 68 CLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQ 127
C+PP+ H+ C LPG C+IP N+ C + + + NG EKETM+FLNDRLA+YLEKVRQLE+
Sbjct: 21 CVPPSCHS-CTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
Query: 128 ENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAAD 187
+NAELE + ERS+ E +CP YQSYF+TIEELQQKILC+K+ENARL+VQIDNAKLAAD
Sbjct: 80 DNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCTKSENARLVVQIDNAKLAAD 139
Query: 188 DFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247
DFR K ++E SL QLVE+D G +++LD+ TL K+DLEAQ ESLKEE L LKSNHEQEV
Sbjct: 140 DFRTKYQTELSLRQLVESDINGLRRILDELTLCKSDLEAQVESLKEELLCLKSNHEQEVN 199
Query: 248 ILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAM 307
LR QLG++ +E+D PT+DLNRVL E R+QYEA+VETN ++VEQWF Q+E ++ Q +
Sbjct: 200 TLRCQLGDRLNVEVDAAPTVDLNRVLNETRSQYEALVETNRREVEQWFTTQTEELNKQVV 259
Query: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLIS 367
S SE+LQ Q+EI+ELR TVNALE+E QAQH L+D L+N+L E+E RY ++L+Q+QSLI+
Sbjct: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQSLIT 319
Query: 368 NLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCST----- 422
N+E QL+EIR+DLERQNQEYQVLLDV+ARLE EI TYR+LLESEDC LP NPC+T
Sbjct: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCNLPSNPCATTNACS 379
Query: 423 ----------------PASCTSC---PSCGP 434
PA CT C P CGP
Sbjct: 380 KPIGPCLSNPCTSCVPPAPCTPCAPRPRCGP 410
>gi|14917117 keratin 33A [Homo sapiens]
Length = 404
Score = 470 bits (1209), Expect = e-132
Identities = 239/381 (62%), Positives = 299/381 (78%), Gaps = 4/381 (1%)
Query: 68 CLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQ 127
C+PP+ H C LPG C+IP N+ C + + + NG EKETM+FLNDRLA+YLEKVRQLE+
Sbjct: 21 CVPPSCH-GCTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
Query: 128 ENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAAD 187
+NAELE + ERS+ E VC YQSYF+TIEELQQKILCSK+ENARL+VQIDNAKLA+D
Sbjct: 80 DNAELENLIRERSQQQEPLVCASYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLASD 139
Query: 188 DFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247
DFR K E+E SL QLVE+D G +++LD+ TL ++DLEAQ ESLKEE L LK NHEQEV
Sbjct: 140 DFRTKYETELSLRQLVESDINGLRRILDELTLCRSDLEAQVESLKEELLCLKQNHEQEVN 199
Query: 248 ILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAM 307
LR QLG++ +E+D PT+DLN+VL E R+QYEA+VETN ++VEQWF Q+E ++ Q +
Sbjct: 200 TLRCQLGDRLNVEVDAAPTVDLNQVLNETRSQYEALVETNRREVEQWFATQTEELNKQVV 259
Query: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLIS 367
S SE+LQ Q+EI+ELR TVNALE+E QAQH L+D L+N+L E+E RY ++L+Q+Q LI+
Sbjct: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEARYSSQLSQVQRLIT 319
Query: 368 NLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPASCT 427
N+E QL+EIR+DLERQNQEYQVLLDV+ARLE EI TYR+LLESEDCKLP NPC+T +C
Sbjct: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACD 379
Query: 428 SCPSCGPVTGGSPSGHGASMG 448
S GP +P G A G
Sbjct: 380 K--STGPCI-SNPCGLRARCG 397
>gi|14917119 keratin 34 [Homo sapiens]
Length = 436
Score = 466 bits (1200), Expect = e-131
Identities = 231/367 (62%), Positives = 294/367 (80%), Gaps = 2/367 (0%)
Query: 68 CLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQ 127
C+PP+ H LPG C+IP N+ C + + + NG EKETM+FLNDRLA+YLEKVRQLE+
Sbjct: 63 CVPPSCH-GYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 121
Query: 128 ENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAAD 187
+NAELE + ERS+ E +CP YQSYF+TIEELQQKILC+KAENARL+V IDNAKLA+D
Sbjct: 122 DNAELEKLIQERSQQQEPLLCPSYQSYFKTIEELQQKILCAKAENARLVVNIDNAKLASD 181
Query: 188 DFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247
DFR K ++E+SL LVE+D +++LD+ TL K+DLE+Q ESL+EE + LK NHE+EV
Sbjct: 182 DFRSKYQTEQSLRLLVESDINSIRRILDELTLCKSDLESQVESLREELICLKKNHEEEVN 241
Query: 248 ILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAM 307
LRSQLG++ +E+D PT+DLN+VL E R+QYEA+VE N ++VEQWF Q+E ++ Q +
Sbjct: 242 TLRSQLGDRLNVEVDTAPTVDLNQVLNETRSQYEALVEINRREVEQWFATQTEELNKQVV 301
Query: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLIS 367
S SE+LQ CQ+EI+ELR TVNALE+E QAQH L+D L+N+L E+E Y ++L+Q+QSLI+
Sbjct: 302 SSSEQLQSCQAEIIELRRTVNALEIELQAQHNLRDSLENTLTESEAHYSSQLSQVQSLIT 361
Query: 368 NLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTP-ASC 426
N+E QL+EIR DLERQNQEYQVLLDV+ARLE EI TYR+LLESEDCKLPCNPC+T AS
Sbjct: 362 NVESQLAEIRCDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPCNPCATTNASG 421
Query: 427 TSCPSCG 433
SC CG
Sbjct: 422 NSCGPCG 428
>gi|10337581 type I hair keratin 3B [Homo sapiens]
Length = 404
Score = 465 bits (1196), Expect = e-131
Identities = 235/373 (63%), Positives = 296/373 (79%), Gaps = 7/373 (1%)
Query: 68 CLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQ 127
C+PP+ H LPG C+IP N+ C + + + NG EKETM+FLNDRLA+YLEKVRQLE+
Sbjct: 21 CVPPSCH-GYTLPGACNIPANVSNCNWFCEGSFNGSEKETMQFLNDRLASYLEKVRQLER 79
Query: 128 ENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAAD 187
+NAELE + ERS+ E +CP YQSYF+TIEELQQKILCSK+ENARL+VQIDNAKLAAD
Sbjct: 80 DNAELENLIRERSQQQEPLLCPSYQSYFKTIEELQQKILCSKSENARLVVQIDNAKLAAD 139
Query: 188 DFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVK 247
DFR K ++E+SL QLVE+D +++LD+ TL ++DLEAQ ESLKEE LSLK NHEQEV
Sbjct: 140 DFRTKYQTEQSLRQLVESDINSLRRILDELTLCRSDLEAQMESLKEELLSLKQNHEQEVN 199
Query: 248 ILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAM 307
LR QLG++ +E+D P +DLN+VL E R QYEA+VETN ++VEQWF Q+E ++ Q +
Sbjct: 200 TLRCQLGDRLNVEVDAAPAVDLNQVLNETRNQYEALVETNRREVEQWFATQTEELNKQVV 259
Query: 308 SCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLIS 367
S SE+LQ Q+EI+ELR TVNALE+E QAQH L+ L+N+L E+E RY ++L+Q+QSLI+
Sbjct: 260 SSSEQLQSYQAEIIELRRTVNALEIELQAQHNLRYSLENTLTESEARYSSQLSQVQSLIT 319
Query: 368 NLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPASCT 427
N+E QL+EIR+DLERQNQEYQVLLDV+ARLE EI TYR+LLESEDCKLP NPC+T +C
Sbjct: 320 NVESQLAEIRSDLERQNQEYQVLLDVRARLECEINTYRSLLESEDCKLPSNPCATTNACE 379
Query: 428 ----SCPS--CGP 434
SC + CGP
Sbjct: 380 KPIGSCVTNPCGP 392
>gi|116488398 keratin 32 [Homo sapiens]
Length = 448
Score = 454 bits (1167), Expect = e-127
Identities = 243/393 (61%), Positives = 295/393 (75%), Gaps = 18/393 (4%)
Query: 65 PSLCLPPTSHTACPLPGT-----CH----IPGNIGICGAYGKNTLNGHEKETMKFLNDRL 115
PS+CLP T A L T C I G++G Y + NG+EKETM+FLNDRL
Sbjct: 48 PSVCLPTTFRPASCLSKTYLSSSCQAASGISGSMGPGSWYSEGAFNGNEKETMQFLNDRL 107
Query: 116 ANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARL 175
A+YL +VRQLEQENAELE+ + E S T+ PDYQS+FRTIEELQQKILC+KAENAR+
Sbjct: 108 ASYLTRVRQLEQENAELESRIQEASHSQVLTMTPDYQSHFRTIEELQQKILCTKAENARM 167
Query: 176 IVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQ 235
+V IDNAKLAADDFR K E+E ++ QLVEAD G +++LDD TL KADLEAQ ESLKEE
Sbjct: 168 VVNIDNAKLAADDFRAKYEAELAMRQLVEADINGLRRILDDLTLCKADLEAQVESLKEEL 227
Query: 236 LSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWF 295
+ LK NHE+EV LR QLG++ IE+D P +DL RVL EMR QYEAMVE N +DVE+WF
Sbjct: 228 MCLKKNHEEEVGSLRCQLGDRLNIEVDAAPPVDLTRVLEEMRCQYEAMVEANRRDVEEWF 287
Query: 296 QAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRY 355
Q E ++ Q + SE+LQ QS+I++LR TVN LE+E QAQH+L+D L+N+L E+E RY
Sbjct: 288 NMQMEELNQQVATSSEQLQNYQSDIIDLRRTVNTLEIELQAQHSLRDSLENTLTESEARY 347
Query: 356 GTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKL 415
++LAQMQ +I+N+E QL+EIRADLERQNQEYQVLLDV+ARLE EI TYR+LLE+EDCKL
Sbjct: 348 SSQLAQMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLEGEINTYRSLLENEDCKL 407
Query: 416 PCNPCSTPASCTSC-PS-------CGPVTGGSP 440
PCNPCSTP SCT+C PS C P T G P
Sbjct: 408 PCNPCSTP-SCTTCVPSPCVPRTVCVPRTVGMP 439
>gi|4504927 keratin 36 [Homo sapiens]
Length = 467
Score = 449 bits (1155), Expect = e-126
Identities = 237/410 (57%), Positives = 299/410 (72%), Gaps = 13/410 (3%)
Query: 31 GCQPVAEANAASMCLLANVAHA----NRVRVGSTPLGRPSLCLPPTSHTACPLPGTCHIP 86
G V+ + C + ++A A + R G + LG CLP + L CH
Sbjct: 24 GISRVSSIRSVGSCRVPSLAGAAGYISSARSGLSGLGS---CLPGSY-----LSSECHTS 75
Query: 87 GNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHEST 146
G +G G + + + NG EKETM+FLNDRLANYLEKVRQLE+ENAELE+ + E +
Sbjct: 76 GFVGSGGWFCEGSFNGSEKETMQFLNDRLANYLEKVRQLERENAELESRIQEWYEFQIPY 135
Query: 147 VCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEAD 206
+CPDYQSYF+TIE+ QQKIL +K+ENARL++QIDNAKLAADDFR K E+E SL QLVEAD
Sbjct: 136 ICPDYQSYFKTIEDFQQKILLTKSENARLVLQIDNAKLAADDFRTKYETELSLRQLVEAD 195
Query: 207 KCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPT 266
G +++LD+ TL KADLEAQ ESLKEE + LK NHE+EV +LR QLG++ +E+D P
Sbjct: 196 INGLRRILDELTLCKADLEAQVESLKEELMCLKKNHEEEVSVLRCQLGDRLNVEVDAAPP 255
Query: 267 IDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCT 326
+DLN++L +MR QYEA+VE N +DVE WF Q+E ++ Q +S SE+LQCCQ+EI+ELR T
Sbjct: 256 VDLNKILEDMRCQYEALVENNRRDVEAWFNTQTEELNQQVVSSSEQLQCCQTEIIELRRT 315
Query: 327 VNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQE 386
VNALE+E QAQH++++ L+++L E E RY ++LAQMQ LISN+E QLSEIR DLERQNQE
Sbjct: 316 VNALEIELQAQHSMRNSLESTLAETEARYSSQLAQMQCLISNVEAQLSEIRCDLERQNQE 375
Query: 387 YQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPAS-CTSCPSCGPV 435
YQVLLDVKARLE EIATYR+LLE EDCKLP PC+T PS PV
Sbjct: 376 YQVLLDVKARLEGEIATYRHLLEGEDCKLPPQPCATACKPVIRVPSVPPV 425
>gi|94538345 keratin 35 [Homo sapiens]
Length = 455
Score = 442 bits (1137), Expect = e-124
Identities = 245/441 (55%), Positives = 304/441 (68%), Gaps = 41/441 (9%)
Query: 1 MTSFYSTSSCPLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGST 60
+++ YS+SSC L +++P AR+ + +G + A+ CL
Sbjct: 28 VSAMYSSSSCKLP-SLSPVARSFSACSVGLG----RSSYRATSCL--------------- 67
Query: 61 PLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYLE 120
P+LCLP T + G G +G+ L G+EKETM+ LNDRLA YLE
Sbjct: 68 ----PALCLPAGGFA------TSYSGGG----GWFGEGILTGNEKETMQSLNDRLAGYLE 113
Query: 121 KVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQID 180
KVRQLEQENA LE+ + E + +CPDYQSYFRTIEELQ+K LCSKAENARL+V+ID
Sbjct: 114 KVRQLEQENASLESRIREWCEQQVPYMCPDYQSYFRTIEELQKKTLCSKAENARLVVEID 173
Query: 181 NAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKS 240
NAKLAADDFR K E+E SL QLVE+D G +++LDD TL K+DLEAQ ESLKEE L LK
Sbjct: 174 NAKLAADDFRTKYETEVSLRQLVESDINGLRRILDDLTLCKSDLEAQVESLKEELLCLKK 233
Query: 241 NHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSE 300
NHE+EV LR QLG++ +E+D P +DLNRVL EMR QYE +VE N +D E W QSE
Sbjct: 234 NHEEEVNSLRCQLGDRLNVEVDAAPPVDLNRVLEEMRCQYETLVENNRRDAEDWLDTQSE 293
Query: 301 GISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELA 360
++ Q +S SE+LQ CQ+EI+ELR TVNALE+E QAQH+++D L+++L E E RY ++LA
Sbjct: 294 ELNQQVVSSSEQLQSCQAEIIELRRTVNALEIELQAQHSMRDALESTLAETEARYSSQLA 353
Query: 361 QMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPC 420
QMQ +I+N+E QL+EIRADLERQNQEYQVLLDV+ARLE EI TYR LLESED KLPCNPC
Sbjct: 354 QMQCMITNVEAQLAEIRADLERQNQEYQVLLDVRARLECEINTYRGLLESEDSKLPCNPC 413
Query: 421 ----STPASCTSC---PSCGP 434
S SC C SCGP
Sbjct: 414 APDYSPSKSCLPCLPAASCGP 434
>gi|125490370 type I hair keratin KA36 [Homo sapiens]
Length = 431
Score = 404 bits (1038), Expect = e-113
Identities = 222/435 (51%), Positives = 285/435 (65%), Gaps = 19/435 (4%)
Query: 1 MTSFYSTSSC-PLGCTMAPGARNVFVSPIDVGCQPVAEANAASMCLLANVAHANRVRVGS 59
MTS S++ C P C A G ++ C P A S C + +R G
Sbjct: 1 MTSDCSSTHCSPESCGTASGCAPASSCSVETACLP--GTCATSRCQTPSFLSRSRGLTG- 57
Query: 60 TPLGRPSLCLPPTSHTACPLPGTCHIPGNIGICGAYGKNTLNGHEKETMKFLNDRLANYL 119
CL P C G+C+ P +G C +EKETM+FLNDRLA+YL
Sbjct: 58 --------CLLP-----CYFTGSCNSPCLVGNCAWCEDGVFTSNEKETMQFLNDRLASYL 104
Query: 120 EKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQI 179
EKVR LE+ NAELE+ + E+ + VCPDYQ YF TIE+LQQKILC+KAEN+RL VQ+
Sbjct: 105 EKVRSLEETNAELESRIQEQCEQDIPMVCPDYQRYFNTIEDLQQKILCTKAENSRLAVQL 164
Query: 180 DNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLK 239
DN KLA DDF+ K ESE SL QL+EAD +L++ TL K+DLEA ESLKE+ L LK
Sbjct: 165 DNCKLATDDFKSKYESELSLRQLLEADISSLHGILEELTLCKSDLEAHVESLKEDLLCLK 224
Query: 240 SNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQS 299
NHE+EV +LR QLG++ +ELD PT+DLNRVL EMR Q E ++ N ++ E+W Q+
Sbjct: 225 KNHEEEVNLLREQLGDRLSVELDTAPTLDLNRVLDEMRCQCETVLANNRREAEEWLAVQT 284
Query: 300 EGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTEL 359
E ++ Q +S +E+LQ CQ EILEL+ T +ALE+E QAQ +L + L+ ++ E E +Y ++L
Sbjct: 285 EELNQQQLSSAEQLQGCQMEILELKRTASALEIELQAQQSLTESLECTVAETEAQYSSQL 344
Query: 360 AQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNP 419
AQ+Q LI NLE QL+EIR DLERQNQEYQVLLDVKARLE EI TY LL+SED +L C+P
Sbjct: 345 AQIQCLIDNLENQLAEIRCDLERQNQEYQVLLDVKARLEGEINTYWGLLDSEDSRLSCSP 404
Query: 420 CSTPASCTSCPSCGP 434
CST +CTS +C P
Sbjct: 405 CST--TCTSSNTCEP 417
>gi|148277620 type I hair keratin KA35 [Homo sapiens]
Length = 491
Score = 385 bits (990), Expect = e-107
Identities = 204/353 (57%), Positives = 259/353 (73%), Gaps = 5/353 (1%)
Query: 92 CGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDY 151
C YG+ +N +EKETM+ LN+RLANYL+KVR LE+ENAELE+ + E S +CPDY
Sbjct: 85 CSWYGEG-INSNEKETMQILNERLANYLQKVRMLERENAELESKIQEESNKELPVLCPDY 143
Query: 152 QSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQ 211
SY+ TIEELQQKILC+KAEN+RL+ QIDN KL ADD R K E+E SL QLVE+D G +
Sbjct: 144 LSYYTTIEELQQKILCTKAENSRLVSQIDNTKLTADDLRAKYEAEVSLRQLVESDANGLK 203
Query: 212 KLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNR 271
++L+ TL KADLEAQ +SLKEE L LK+NH++E+ L+ QLGE+ IE+ P+ DLN+
Sbjct: 204 QILNVLTLGKADLEAQVQSLKEELLCLKNNHKEEINSLQCQLGERLDIEVTAAPSADLNQ 263
Query: 272 VLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALE 331
VL EMR QYE ++ETN +DVEQWF Q E ++ Q ++ S++ QCCQ EI+ELR +VN LE
Sbjct: 264 VLQEMRCQYEPIMETNRKDVEQWFNTQIEELNQQVVTSSQQQQCCQKEIIELRRSVNTLE 323
Query: 332 VERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLL 391
VE QAQH ++D + L E E RY L Q+QSLI NLE QL+EIR LERQNQEY++LL
Sbjct: 324 VELQAQHRMRDSQECILTETEARYTALLTQIQSLIDNLEAQLAEIRCALERQNQEYEILL 383
Query: 392 DVKARLENEIATYRNLLESEDCKLPCNPCST---PASCTSCPSCGPVTGGSPS 441
DVK+RLE EI TYR+LLES D K PC P +T P+ TSC S G + +P+
Sbjct: 384 DVKSRLECEITTYRSLLESSDGKRPCYPRATKCEPSPWTSCKS-GAIESTAPA 435
>gi|4557701 keratin 17 [Homo sapiens]
Length = 432
Score = 323 bits (827), Expect = 3e-88
Identities = 179/391 (45%), Positives = 254/391 (64%), Gaps = 17/391 (4%)
Query: 31 GCQPVAEANAASMCLLANVAHANRVRVGSTPLGRPSLCLPPTSHTACPLPGTCHIPGNIG 90
G + ++ + C L+ A R+GS G L +S+++C + G
Sbjct: 16 GSSGLGGGSSRTSCRLSGGLGAGSCRLGSA--GGLGSTLGGSSYSSCY---------SFG 64
Query: 91 ICGAYGKN------TLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHE 144
G YG + L G EK TM+ LNDRLA+YL+KVR LE+ N ELE + + +
Sbjct: 65 SGGGYGSSFGGVDGLLAGGEKATMQNLNDRLASYLDKVRALEEANTELEVKIRDWYQRQA 124
Query: 145 STVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVE 204
DY Y+RTIEELQ KIL + +NA +++QIDNA+LAADDFR K E+E++L VE
Sbjct: 125 PGPARDYSQYYRTIEELQNKILTATVDNANILLQIDNARLAADDFRTKFETEQALRLSVE 184
Query: 205 ADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIE 264
AD G +++LD+ TLA+ADLE Q E+LKEE LK NHE+E+ LR Q+G + +E+D
Sbjct: 185 ADINGLRRVLDELTLARADLEMQIENLKEELAYLKKNHEEEMNALRGQVGGEINVEMDAA 244
Query: 265 PTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELR 324
P +DL+R+L EMR QYE M E N +D E WF +++E ++ + + SE +Q +SEI ELR
Sbjct: 245 PGVDLSRILNEMRDQYEKMAEKNRKDAEDWFFSKTEELNREVATNSELVQSGKSEISELR 304
Query: 325 CTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQN 384
T+ ALE+E Q+Q ++K L+ +L E E+RY +L+Q+Q LI ++EEQL+++R ++E+QN
Sbjct: 305 RTMQALEIELQSQLSMKASLEGNLAETENRYCVQLSQIQGLIGSVEEQLAQLRCEMEQQN 364
Query: 385 QEYQVLLDVKARLENEIATYRNLLESEDCKL 415
QEY++LLDVK RLE EIATYR LLE ED L
Sbjct: 365 QEYKILLDVKTRLEQEIATYRRLLEGEDAHL 395
>gi|24430190 keratin 15 [Homo sapiens]
Length = 456
Score = 317 bits (811), Expect = 2e-86
Identities = 169/331 (51%), Positives = 234/331 (70%), Gaps = 6/331 (1%)
Query: 90 GICGAYGKNT---LNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLE--RSKCHE 144
G G +G L+G+EK TM+ LNDRLA+YL+KVR LE+ NA+LE + + + +
Sbjct: 88 GFGGGFGGGDGGLLSGNEKITMQNLNDRLASYLDKVRALEEANADLEVKIHDWYQKQTPT 147
Query: 145 STVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVE 204
S C DY YF+TIEEL+ KI+ + +N+R+I++IDNA+LAADDFR+K E+E +L Q VE
Sbjct: 148 SPEC-DYSQYFKTIEELRDKIMATTIDNSRVILEIDNARLAADDFRLKYENELALRQGVE 206
Query: 205 ADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIE 264
AD G +++LD+ TLA+ DLE Q E L EE LK NHE+E+K SQL + +E+D
Sbjct: 207 ADINGLRRVLDELTLARTDLEMQIEGLNEELAYLKKNHEEEMKEFSSQLAGQVNVEMDAA 266
Query: 265 PTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELR 324
P +DL RVL EMR QYEAM E N +DVE WF +++E ++ + S +E +Q ++EI +LR
Sbjct: 267 PGVDLTRVLAEMREQYEAMAEKNRRDVEAWFFSKTEELNKEVASNTEMIQTSKTEITDLR 326
Query: 325 CTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQN 384
T+ LE+E Q+Q ++K L+NSL E E RY T+L Q+Q LI LE QLSE+R ++E QN
Sbjct: 327 RTMQELEIELQSQLSMKAGLENSLAETECRYATQLQQIQGLIGGLEAQLSELRCEMEAQN 386
Query: 385 QEYQVLLDVKARLENEIATYRNLLESEDCKL 415
QEY++LLD+K RLE EIATYR+LLE +D K+
Sbjct: 387 QEYKMLLDIKTRLEQEIATYRSLLEGQDAKM 417
>gi|15431310 keratin 14 [Homo sapiens]
Length = 472
Score = 316 bits (810), Expect = 2e-86
Identities = 168/336 (50%), Positives = 232/336 (69%)
Query: 87 GNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHEST 146
G G A G L G EK TM+ LNDRLA+YL+KVR LE+ NA+LE + + +
Sbjct: 98 GGFGGGFAGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPA 157
Query: 147 VCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEAD 206
DY YF+TIE+L+ KIL + +NA +++QIDNA+LAADDFR K E+E +L VEAD
Sbjct: 158 EIKDYSPYFKTIEDLRNKILTATVDNANVLLQIDNARLAADDFRTKYETELNLRMSVEAD 217
Query: 207 KCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPT 266
G +++LD+ TLA+ADLE Q ESLKEE LK NHE+E+ LR Q+G +E+D P
Sbjct: 218 INGLRRVLDELTLARADLEMQIESLKEELAYLKKNHEEEMNALRGQVGGDVNVEMDAAPG 277
Query: 267 IDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCT 326
+DL+R+L EMR QYE M E N +D E+WF ++E ++ + + SE +Q +SEI ELR T
Sbjct: 278 VDLSRILNEMRDQYEKMAEKNRKDAEEWFFTKTEELNREVATNSELVQSGKSEISELRRT 337
Query: 327 VNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQE 386
+ LE+E Q+Q ++K L+NSL E + RY +LAQ+Q +I ++EEQL+++R ++E+QNQE
Sbjct: 338 MQNLEIELQSQLSMKASLENSLEETKGRYCMQLAQIQEMIGSVEEQLAQLRCEMEQQNQE 397
Query: 387 YQVLLDVKARLENEIATYRNLLESEDCKLPCNPCST 422
Y++LLDVK RLE EIATYR LLE ED L + S+
Sbjct: 398 YKILLDVKTRLEQEIATYRRLLEGEDAHLSSSQFSS 433
>gi|131412225 keratin 13 isoform a [Homo sapiens]
Length = 458
Score = 313 bits (801), Expect = 3e-85
Identities = 174/362 (48%), Positives = 241/362 (66%), Gaps = 9/362 (2%)
Query: 93 GAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCP--D 150
GA L G+EK TM+ LNDRLA+YLEKVR LE+ NA+LE + + +S P D
Sbjct: 93 GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWH-LKQSPASPERD 151
Query: 151 YQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGT 210
Y Y++TIEEL+ KIL + EN R+I++IDNA+LAADDFR+K E+E +L Q VEAD G
Sbjct: 152 YSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGL 211
Query: 211 QKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLN 270
+++LD+ TL+K DLE Q ESL EE +K NHE+E+K +Q+ + +E+D P IDL
Sbjct: 212 RRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLT 271
Query: 271 RVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNAL 330
RVL EMR QYEAM E N +D E+WF A+S ++ + + + +Q ++EI ELR T+ L
Sbjct: 272 RVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGL 331
Query: 331 EVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVL 390
E+E Q+Q ++K L+N++ E E RY +L Q+Q LIS++E QLSE+R+++E QNQEY++L
Sbjct: 332 EIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKML 391
Query: 391 LDVKARLENEIATYRNLLESEDCKLPCNPCST------PASCTSCPSCGPVTGGSPSGHG 444
LD+K RLE EIATYR+LLE +D K+ P S S T+ S T + SG
Sbjct: 392 LDIKTRLEQEIATYRSLLEGQDAKMIGFPSSAGSVSPRSTSVTTTSSASVTTTSNASGRR 451
Query: 445 AS 446
S
Sbjct: 452 TS 453
>gi|24430192 keratin 16 [Homo sapiens]
Length = 473
Score = 311 bits (798), Expect = 6e-85
Identities = 164/328 (50%), Positives = 225/328 (68%)
Query: 94 AYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQS 153
A G L G EK TM+ LNDRLA+YL+KVR LE+ NA+LE + + + + DY
Sbjct: 107 AGGDGLLVGSEKVTMQNLNDRLASYLDKVRALEEANADLEVKIRDWYQRQRPSEIKDYSP 166
Query: 154 YFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKL 213
YF+TIE+L+ KI+ + ENA+ I+QIDNA+LAADDFR K E E +L Q VEAD G +++
Sbjct: 167 YFKTIEDLRNKIIAATIENAQPILQIDNARLAADDFRTKYEHELALRQTVEADVNGLRRV 226
Query: 214 LDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVL 273
LD+ TLA+ DLE Q E LKEE L+ NHE+E+ LR Q G +E+D P +DL+R+L
Sbjct: 227 LDELTLARTDLEMQIEGLKEELAYLRKNHEEEMLALRGQTGGDVNVEMDAAPGVDLSRIL 286
Query: 274 GEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVE 333
EMR QYE M E N +D E WF +++E ++ + S SE +Q +SE+ ELR + LE+E
Sbjct: 287 NEMRDQYEQMAEKNRRDAETWFLSKTEELNKEVASNSELVQSSRSEVTELRRVLQGLEIE 346
Query: 334 RQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDV 393
Q+Q ++K L+NSL E + RY +L+Q+Q LI ++EEQL+++R ++E+Q+QEYQ+LLDV
Sbjct: 347 LQSQLSMKASLENSLEETKGRYCMQLSQIQGLIGSVEEQLAQLRCEMEQQSQEYQILLDV 406
Query: 394 KARLENEIATYRNLLESEDCKLPCNPCS 421
K RLE EIATYR LLE ED L S
Sbjct: 407 KTRLEQEIATYRRLLEGEDAHLSSQQAS 434
>gi|131412228 keratin 13 isoform b [Homo sapiens]
Length = 420
Score = 309 bits (792), Expect = 3e-84
Identities = 165/324 (50%), Positives = 229/324 (70%), Gaps = 3/324 (0%)
Query: 93 GAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCP--D 150
GA L G+EK TM+ LNDRLA+YLEKVR LE+ NA+LE + + +S P D
Sbjct: 93 GACDGGLLTGNEKITMQNLNDRLASYLEKVRALEEANADLEVKIRDWH-LKQSPASPERD 151
Query: 151 YQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGT 210
Y Y++TIEEL+ KIL + EN R+I++IDNA+LAADDFR+K E+E +L Q VEAD G
Sbjct: 152 YSPYYKTIEELRDKILTATIENNRVILEIDNARLAADDFRLKYENELALRQSVEADINGL 211
Query: 211 QKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLN 270
+++LD+ TL+K DLE Q ESL EE +K NHE+E+K +Q+ + +E+D P IDL
Sbjct: 212 RRVLDELTLSKTDLEMQIESLNEELAYMKKNHEEEMKEFSNQVVGQVNVEMDATPGIDLT 271
Query: 271 RVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNAL 330
RVL EMR QYEAM E N +D E+WF A+S ++ + + + +Q ++EI ELR T+ L
Sbjct: 272 RVLAEMREQYEAMAERNRRDAEEWFHAKSAELNKEVSTNTAMIQTSKTEITELRRTLQGL 331
Query: 331 EVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVL 390
E+E Q+Q ++K L+N++ E E RY +L Q+Q LIS++E QLSE+R+++E QNQEY++L
Sbjct: 332 EIELQSQLSMKAGLENTVAETECRYALQLQQIQGLISSIEAQLSELRSEMECQNQEYKML 391
Query: 391 LDVKARLENEIATYRNLLESEDCK 414
LD+K RLE EIATYR+LLE +D K
Sbjct: 392 LDIKTRLEQEIATYRSLLEGQDAK 415
>gi|24234699 keratin 19 [Homo sapiens]
Length = 400
Score = 305 bits (780), Expect = 7e-83
Identities = 154/313 (49%), Positives = 222/313 (70%)
Query: 100 LNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIE 159
L G+EK TM+ LNDRLA+YL+KVR LE N ELE + + + DY Y+ TI+
Sbjct: 76 LAGNEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQ 135
Query: 160 ELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATL 219
+L+ KIL + EN+R+++QIDNA+LAADDFR K E+E++L VEAD G +++LD+ TL
Sbjct: 136 DLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTL 195
Query: 220 AKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGEMRAQ 279
A+ DLE Q E LKEE LK NHE+E+ LR Q+G + +E+D P DL ++L +MR+Q
Sbjct: 196 ARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVGGQVSVEVDSAPGTDLAKILSDMRSQ 255
Query: 280 YEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHT 339
YE M E N +D E WF +++E ++ + +E+LQ +SE+ +LR T+ LE+E Q+Q +
Sbjct: 256 YEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLS 315
Query: 340 LKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLEN 399
+K L+++L E E R+G +LA +Q+LIS +E QL ++RAD ERQNQEYQ L+D+K+RLE
Sbjct: 316 MKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQ 375
Query: 400 EIATYRNLLESED 412
EIATYR+LLE ++
Sbjct: 376 EIATYRSLLEGQE 388
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 292 bits (747), Expect = 5e-79
Identities = 170/364 (46%), Positives = 234/364 (64%), Gaps = 13/364 (3%)
Query: 90 GICGAYGKN--TLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHEST- 146
G G +G + L+G+EK TM+ LNDRLA+YL+KVR LE+ N ELE + E + H ++
Sbjct: 130 GFGGGFGGDGGLLSGNEKVTMQNLNDRLASYLDKVRALEESNYELEGKIKEWYEKHGNSH 189
Query: 147 --VCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVE 204
DY Y++TI++L+ +IL +NA +++QIDNA+LAADDFR+K E+E +L Q VE
Sbjct: 190 QGEPRDYSKYYKTIDDLKNQILNLTTDNANILLQIDNARLAADDFRLKYENEVALRQSVE 249
Query: 205 ADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIE 264
AD G +++LD+ TL KADLE Q ESL EE LK NHE+E+K LR+ +E++
Sbjct: 250 ADINGLRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNVEMNAA 309
Query: 265 PTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELR 324
P +DL ++L MR+QYE + E N +D E WF +S+ ++ + + E++ +SEI ELR
Sbjct: 310 PGVDLTQLLNNMRSQYEQLAEQNRKDAEAWFNEKSKELTTEIDNNIEQISSYKSEITELR 369
Query: 325 CTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQN 384
V ALE+E Q+Q LK L+ SL E E RY +L+Q+Q+ IS LEEQL +IRA+ E QN
Sbjct: 370 RNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISALEEQLQQIRAETECQN 429
Query: 385 QEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPASCTSCPSCGPVTGGSPSGHG 444
EYQ LLD+K RLENEI TYR+LLE E S+ S G GG SG G
Sbjct: 430 TEYQQLLDIKIRLENEIQTYRSLLEGEG--------SSGGGGRGGGSFGGGYGGGSSGGG 481
Query: 445 ASMG 448
+S G
Sbjct: 482 SSGG 485
>gi|4557699 keratin 12 [Homo sapiens]
Length = 494
Score = 281 bits (719), Expect = 8e-76
Identities = 155/329 (47%), Positives = 215/329 (65%), Gaps = 4/329 (1%)
Query: 87 GNIGICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLE----RSKC 142
G++GI L+G EKETM+ LNDRLA+YL+KVR LE+ N ELE + E R
Sbjct: 108 GSLGILSGNDGGLLSGSEKETMQNLNDRLASYLDKVRALEEANTELENKIREWYETRGTG 167
Query: 143 HESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQL 202
DY Y+ IE+L+ KI+ + NA+L++QIDNA+LAA+DFR+K E+E +L Q
Sbjct: 168 TADASQSDYSKYYPLIEDLRNKIISASIGNAQLLLQIDNARLAAEDFRMKYENELALRQG 227
Query: 203 VEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELD 262
VEAD G +++LD+ TL + DLE Q ESL EE +K NHE E++ R + +E+D
Sbjct: 228 VEADINGLRRVLDELTLTRTDLEMQIESLNEELAYMKKNHEDELQSFRVGGPGEVSVEMD 287
Query: 263 IEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILE 322
P +DL R+L +MRAQYE + E N +D E WF +S + + + +E+LQ +SE+ +
Sbjct: 288 AAPGVDLTRLLNDMRAQYETIAEQNRKDAEAWFIEKSGELRKEISTNTEQLQSSKSEVTD 347
Query: 323 LRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLER 382
LR LE+E Q+Q +K L++SL EAE Y +L+Q+Q LISNLE QL ++RAD ER
Sbjct: 348 LRRAFQNLEIELQSQLAMKKSLEDSLAEAEGDYCAQLSQVQQLISNLEAQLLQVRADAER 407
Query: 383 QNQEYQVLLDVKARLENEIATYRNLLESE 411
QN ++Q LL+VKARLE EI TYR LL+ E
Sbjct: 408 QNVDHQRLLNVKARLELEIETYRRLLDGE 436
>gi|27894337 keratin 20 [Homo sapiens]
Length = 424
Score = 278 bits (710), Expect = 9e-75
Identities = 145/319 (45%), Positives = 213/319 (66%)
Query: 96 GKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYF 155
G + G+EK M+ LNDRLA+YLEKVR LEQ N++LE + + + + DY +Y+
Sbjct: 62 GGDLFVGNEKMAMQNLNDRLASYLEKVRTLEQSNSKLEVQIKQWYETNAPRAGRDYSAYY 121
Query: 156 RTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLD 215
R IEEL+ +I ++ +NAR ++QIDNAKLAA+DFR+K E+ER + VEAD G K+ D
Sbjct: 122 RQIEELRSQIKDAQLQNARCVLQIDNAKLAAEDFRLKYETERGIRLTVEADLQGLNKVFD 181
Query: 216 DATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLGE 275
D TL K DLE Q E L ++ LK H++EV L LG +E+D P ++L ++ E
Sbjct: 182 DLTLHKTDLEIQIEELNKDLALLKKEHQEEVDGLHKHLGNTVNVEVDAAPGLNLGVIMNE 241
Query: 276 MRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQ 335
MR +YE M + N Q+ ++ F+ Q+ + Q +EEL+ + ++ ELR T +LE+E Q
Sbjct: 242 MRQKYEVMAQKNLQEAKEQFERQTAVLQQQVTVNTEELKGTEVQLTELRRTSQSLEIELQ 301
Query: 336 AQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKA 395
+ ++K+ L+++L E + RY ++LA +QSL+S+LE QL +IR+++ERQN EY +LLD+K
Sbjct: 302 SHLSMKESLEHTLEETKARYSSQLANLQSLLSSLEAQLMQIRSNMERQNNEYHILLDIKT 361
Query: 396 RLENEIATYRNLLESEDCK 414
RLE EIATYR LLE ED K
Sbjct: 362 RLEQEIATYRRLLEGEDVK 380
>gi|114431246 keratin 25D [Homo sapiens]
Length = 464
Score = 265 bits (676), Expect = 8e-71
Identities = 152/352 (43%), Positives = 209/352 (59%), Gaps = 14/352 (3%)
Query: 79 LPGTCHIPGNIGICGAYG-----KNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELE 133
+PG H G +G G L+G+EK TM+ LNDRLA+YL+ VR LE+ NAELE
Sbjct: 56 VPGGSHAGGALGNAACIGFAGSEGGLLSGNEKVTMQNLNDRLASYLDNVRALEEANAELE 115
Query: 134 TTLLERSKCHESTVCP----DYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDF 189
+ + + C DY Y TIE+L+ KI+ S NA +I+QIDNA+LAADDF
Sbjct: 116 RKIKGWYEKYGPGSCRGLDHDYSRYHLTIEDLKNKIISSTTTNANVILQIDNARLAADDF 175
Query: 190 RIKLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKIL 249
R+K E+E +LHQ VEAD G +++LD+ TL + D E Q ESL EE LK NHE+E+K L
Sbjct: 176 RLKYENELTLHQNVEADINGLRRVLDELTLCRTDQELQYESLSEEMTYLKKNHEEEMKAL 235
Query: 250 RSQLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSC 309
+ G +E++ P +DL +L MRA+YEA+ E N +D E WF +S + Q
Sbjct: 236 QCAAGGNVNVEMNAAPGVDLAVLLNNMRAEYEALAEQNRKDAEAWFNEKSASLQQQISHD 295
Query: 310 SEELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNL 369
S +S++ E+R T+ LE++ Q+ K L+ SL E E Y T+LAQ+Q+ I L
Sbjct: 296 SGAATFARSQLTEMRRTLQTLEIQLQSLMATKHSLECSLTETESNYCTQLAQIQAQIGAL 355
Query: 370 EEQLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESEDCKLPCNPCS 421
EEQL ++R + E Q EY+ LLDVK LE EI TY L++ + N CS
Sbjct: 356 EEQLHQVRTETEGQKLEYEHLLDVKVHLEKEIETYCRLIDGDG-----NSCS 402
>gi|153945736 keratin 27 [Homo sapiens]
Length = 459
Score = 256 bits (655), Expect = 2e-68
Identities = 141/333 (42%), Positives = 202/333 (60%), Gaps = 7/333 (2%)
Query: 87 GNIGICGAYGKNT---LNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCH 143
G C A+ N L+G+EK TM+ LNDRLA+YLE VR LE+ NA+LE + +
Sbjct: 64 GGSASCAAFTGNEHGLLSGNEKVTMQNLNDRLASYLENVRALEEANADLEQKIKGWYEKF 123
Query: 144 ESTVCP----DYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSL 199
C DY YF I+EL+ +I+ + NA +++Q DNA+L ADDFR+K E+E +L
Sbjct: 124 GPGSCRGLDHDYSRYFPIIDELKNQIISATTSNAHVVLQNDNARLTADDFRLKFENELAL 183
Query: 200 HQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRI 259
HQ VEAD G +++LD+ TL + DLE Q E+L EE LK NHE+E+K L+ G +
Sbjct: 184 HQSVEADINGLRRVLDELTLCRTDLEIQLETLSEELAYLKKNHEEEMKALQCAAGGNVNV 243
Query: 260 ELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSE 319
E++ P +DL +L MRA+YEA+ E N +D E WF +S + Q + ++E
Sbjct: 244 EMNAAPGVDLTVLLNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNE 303
Query: 320 ILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRAD 379
++E++ T+ LE+E Q+ K L+ SL E E Y +LAQ+Q+ I LEEQL ++R +
Sbjct: 304 LIEMKRTLQTLEIELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTE 363
Query: 380 LERQNQEYQVLLDVKARLENEIATYRNLLESED 412
E Q EY+ LLD+K LE EI TY L++ ED
Sbjct: 364 TEGQKLEYEQLLDIKVHLEKEIETYCLLIDGED 396
>gi|192807292 keratin 24 [Homo sapiens]
Length = 525
Score = 254 bits (650), Expect = 9e-68
Identities = 140/328 (42%), Positives = 208/328 (63%), Gaps = 6/328 (1%)
Query: 90 GICGAYGKNTL-NGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCH----- 143
G+ G G L +G EK+TM+ LNDRLANYL+KVR LE+ N +LE + E +
Sbjct: 125 GMGGGVGDGGLFSGGEKQTMQNLNDRLANYLDKVRALEEANTDLENKIKEWYDKYGPGSG 184
Query: 144 ESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLV 203
+ DY Y+ IE+L+ +I+ + ENA +I+ IDNA+LAADDFR+K E+E L Q V
Sbjct: 185 DGGSGRDYSKYYSIIEDLRNQIIAATVENAGIILHIDNARLAADDFRLKYENELCLRQSV 244
Query: 204 EADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDI 263
EAD G +K+LDD T+ ++DLE Q ES EE L+ NHE+E+K ++ G + +E++
Sbjct: 245 EADINGLRKVLDDLTMTRSDLEMQIESFTEELAYLRKNHEEEMKNMQGSSGGEVTVEMNA 304
Query: 264 EPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILEL 323
P DL ++L +MRAQYE + E N ++ E+ F QS + Q + + ++EI EL
Sbjct: 305 APGTDLTKLLNDMRAQYEELAEQNRREAEERFNKQSASLQAQISTDAGAATSAKNEITEL 364
Query: 324 RCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQ 383
+ T+ ALE+E Q+Q +K L+ +L + E Y +L+++Q+ IS LEE++ +I + + Q
Sbjct: 365 KRTLQALEIELQSQLAMKSSLEGTLADTEAGYVAQLSEIQTQISALEEEICQIWGETKCQ 424
Query: 384 NQEYQVLLDVKARLENEIATYRNLLESE 411
N EY+ LLD+K RLE EI TYR LL+ E
Sbjct: 425 NAEYKQLLDIKTRLEVEIETYRRLLDGE 452
>gi|31559829 keratin 25 [Homo sapiens]
Length = 450
Score = 249 bits (635), Expect = 5e-66
Identities = 135/324 (41%), Positives = 197/324 (60%), Gaps = 6/324 (1%)
Query: 97 KNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCP----DYQ 152
+ L+G+EK TM+ LNDRLA+YL+ V LE+ NA+LE + + C DY
Sbjct: 72 RGLLSGNEKVTMQNLNDRLASYLDSVHALEEANADLEQKIKGWYEKFGPGSCRGLDHDYS 131
Query: 153 SYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQK 212
YF I++L+ +I+ S NA ++QIDNA+L ADDFR+K E+E +LHQ VEAD G ++
Sbjct: 132 RYFPIIDDLKNQIIASTTSNANAVLQIDNARLTADDFRLKYENELALHQSVEADVNGLRR 191
Query: 213 LLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRV 272
+LD+ TL + DLE Q E+L EE LK NH++E+++L+ G +E++ P +DL +
Sbjct: 192 VLDEITLCRTDLEIQYETLSEEMTYLKKNHKEEMQVLQCAAGGNVNVEMNAAPGVDLTVL 251
Query: 273 LGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEV 332
L MRA+YEA+ E N +D E WF +S + Q ++E+ E++ T+ LE+
Sbjct: 252 LNNMRAEYEALAEQNRRDAEAWFNEKSASLQQQISEDVGATTSARNELTEMKRTLQTLEI 311
Query: 333 ERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLD 392
E Q+ K L+ SL E E Y +LAQ+Q+ I LEEQL ++R + E Q EY+ LLD
Sbjct: 312 ELQSLLATKHSLECSLTETESNYCAQLAQIQAQIGALEEQLHQVRTETEGQKLEYEQLLD 371
Query: 393 VKARLENEIATYRNLLESED--CK 414
+K LE EI TY L+ +D CK
Sbjct: 372 IKLHLEKEIETYCLLIGGDDGACK 395
>gi|40354195 keratin 18 [Homo sapiens]
Length = 430
Score = 249 bits (635), Expect = 5e-66
Identities = 131/315 (41%), Positives = 209/315 (66%), Gaps = 3/315 (0%)
Query: 103 HEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQ 162
+EKETM+ LNDRLA+YL++VR LE EN LE+ + E + V D+ YF+ IE+L+
Sbjct: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
Query: 163 QKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKA 222
+I + +NAR+++QIDNA+LAADDFR+K E+E ++ Q VE D G +K++DD + +
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
Query: 223 DLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEK-FRIELDIEPTIDLNRVLGEMRAQYE 281
LE + E+LKEE L +K NHE+EVK L++Q+ +E+D + DL +++ ++RAQY+
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
Query: 282 AMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLK 341
+ N +++++++ Q E + + S E+ ++ + ELR TV +LE++ + LK
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
Query: 342 DCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEI 401
L+NSL E E RY ++ Q+ ++ +LE +L++ RA+ +RQ QEY+ LL++K +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
Query: 402 ATYRNLLE-SEDCKL 415
ATYR LLE ED L
Sbjct: 378 ATYRRLLEDGEDFNL 392
>gi|4557888 keratin 18 [Homo sapiens]
Length = 430
Score = 249 bits (635), Expect = 5e-66
Identities = 131/315 (41%), Positives = 209/315 (66%), Gaps = 3/315 (0%)
Query: 103 HEKETMKFLNDRLANYLEKVRQLEQENAELETTLLERSKCHESTVCPDYQSYFRTIEELQ 162
+EKETM+ LNDRLA+YL++VR LE EN LE+ + E + V D+ YF+ IE+L+
Sbjct: 79 NEKETMQSLNDRLASYLDRVRSLETENRRLESKIREHLEKKGPQV-RDWSHYFKIIEDLR 137
Query: 163 QKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLLDDATLAKA 222
+I + +NAR+++QIDNA+LAADDFR+K E+E ++ Q VE D G +K++DD + +
Sbjct: 138 AQIFANTVDNARIVLQIDNARLAADDFRVKYETELAMRQSVENDIHGLRKVIDDTNITRL 197
Query: 223 DLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEK-FRIELDIEPTIDLNRVLGEMRAQYE 281
LE + E+LKEE L +K NHE+EVK L++Q+ +E+D + DL +++ ++RAQY+
Sbjct: 198 QLETEIEALKEELLFMKKNHEEEVKGLQAQIASSGLTVEVDAPKSQDLAKIMADIRAQYD 257
Query: 282 AMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVERQAQHTLK 341
+ N +++++++ Q E + + S E+ ++ + ELR TV +LE++ + LK
Sbjct: 258 ELARKNREELDKYWSQQIEESTTVVTTQSAEVGAAETTLTELRRTVQSLEIDLDSMRNLK 317
Query: 342 DCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVKARLENEI 401
L+NSL E E RY ++ Q+ ++ +LE +L++ RA+ +RQ QEY+ LL++K +LE EI
Sbjct: 318 ASLENSLREVEARYALQMEQLNGILLHLESELAQTRAEGQRQAQEYEALLNIKVKLEAEI 377
Query: 402 ATYRNLLE-SEDCKL 415
ATYR LLE ED L
Sbjct: 378 ATYRRLLEDGEDFNL 392
>gi|27894339 keratin 23 [Homo sapiens]
Length = 422
Score = 246 bits (628), Expect = 3e-65
Identities = 135/340 (39%), Positives = 208/340 (61%), Gaps = 16/340 (4%)
Query: 76 ACPLPGTCHIPGNIGICGAYGKNT----LNGHEKETMKFLNDRLANYLEKVRQLEQENAE 131
+CP PG G++G L G+ K TM+ LNDRLA+YLEKVR LE+ N +
Sbjct: 51 SCPPPG-----------GSWGSGRSSPLLGGNGKATMQNLNDRLASYLEKVRALEEANMK 99
Query: 132 LETTLLERSKCHESTVCPDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRI 191
LE+ +L+ + + DY Y I LQ++I+ K NA++I+ IDNA++A DDF +
Sbjct: 100 LESRILKWHQQRDPGSKKDYSQYEENITHLQEQIVDGKMTNAQIILLIDNARMAVDDFNL 159
Query: 192 KLESERSLHQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRS 251
K E+E S + +E + G ++ LD+ T+ DLE + E +++E + +K +HEQE++
Sbjct: 160 KYENEHSFKKDLEIEVEGLRRTLDNLTIVTTDLEQEVEGMRKELILMKKHHEQEMEKHHV 219
Query: 252 QLGEKFRIELDIEPTIDLNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSE 311
+++D P DL +VL +MR +YE +++ H+D++ W++ QS +S +A S
Sbjct: 220 PSDFNVNVKVDTGPREDLIKVLEDMRQEYELIIKKKHRDLDTWYKEQSAAMSQEAAS-PA 278
Query: 312 ELQCCQSEILELRCTVNALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEE 371
+Q Q +I EL+ T ALE++ Q Q++ K L+N L E + RY +L MQ +IS+ EE
Sbjct: 279 TVQSRQGDIHELKRTFQALEIDLQTQYSTKSALENMLSETQSRYSCKLQDMQEIISHYEE 338
Query: 372 QLSEIRADLERQNQEYQVLLDVKARLENEIATYRNLLESE 411
+L+++R +LERQN EYQVLL +K LE EI TYR LLE E
Sbjct: 339 ELTQLRHELERQNNEYQVLLGIKTHLEKEITTYRRLLEGE 378
>gi|31559815 keratin 26 [Homo sapiens]
Length = 468
Score = 242 bits (618), Expect = 4e-64
Identities = 149/405 (36%), Positives = 223/405 (55%), Gaps = 24/405 (5%)
Query: 52 ANRVRVGSTPLGRPSLCLPPTSHTA--CPLPGT------CHIPGNIG--ICGAYGKNT-- 99
+ R+ G T ++C+ + ++ C L G C+ G +G C + N
Sbjct: 18 SGRLSGGGTGFVAGNVCVGSGARSSFSCTLEGISSGGSFCNSGGGLGSGACAGFLGNEHS 77
Query: 100 -LNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLER-SKCHESTVCP---DYQSY 154
L+G+EK TM+ LNDRLA+YL+ V LE+ NA+LE + R KC + DY Y
Sbjct: 78 LLSGNEKVTMQNLNDRLASYLDHVHALEEANADLEQKIKGRYEKCEPGSSREHDHDYSRY 137
Query: 155 FRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKCGTQKLL 214
F IE+L+++I + NA +++Q DNA+L ADDFR+K E+E +LH VEAD G +++L
Sbjct: 138 FSVIEDLKRQITSATICNASIVLQNDNARLTADDFRLKYENELALHHSVEADTSGLRRVL 197
Query: 215 DDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTIDLNRVLG 274
D+ TL DLE Q E+L EE LK +HE+E+++L+ G +E++ P +DL +L
Sbjct: 198 DELTLCTTDLEIQCETLSEELTYLKKSHEEEMEVLQYTAGGNVNVEMNATPGVDLTVLLN 257
Query: 275 EMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVNALEVER 334
MRA+YE + E N +D E WF +S + Q ++E+ EL+ + LE+E
Sbjct: 258 NMRAEYEDLAEQNRKDAEAWFNERSATLQQQISDHEGAATAARNELTELKRNLQTLEIEL 317
Query: 335 QAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQVLLDVK 394
Q+ +K + SL E E Y +L Q+Q I +EEQL +IR + E Q EY+ LLDVK
Sbjct: 318 QSLMAVKHSYECSLAETEGNYCNQLQQIQDQIGVMEEQLQQIRTETEGQKLEYEQLLDVK 377
Query: 395 ARLENEIATYRNLLESEDCKLPCNPCSTPASCTSCPSCGPVTGGS 439
LE EI Y NLL+ E+ K + ++C PV G+
Sbjct: 378 IFLEKEIDIYCNLLDGEERK-------SKSTCYKSKGYRPVNSGN 415
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 239 bits (611), Expect = 3e-63
Identities = 134/360 (37%), Positives = 209/360 (58%), Gaps = 1/360 (0%)
Query: 90 GICGAYGKNTLNGHEKETMKFLNDRLANYLEKVRQLEQENAELETTLLE-RSKCHESTVC 148
G G L +EK TM+ LN RLA+YL+KV+ LE+ N +LE + + K + +
Sbjct: 139 GGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLENKIQDWYDKKGPAAIQ 198
Query: 149 PDYQSYFRTIEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESERSLHQLVEADKC 208
+Y Y+ TI++L+ +I+ N + ++ IDN ++ DDFRIK E E++L Q V+AD
Sbjct: 199 KNYSPYYNTIDDLKDQIVDLTVGNNKTLLDIDNTRMTLDDFRIKFEMEQNLRQGVDADIN 258
Query: 209 GTQKLLDDATLAKADLEAQQESLKEEQLSLKSNHEQEVKILRSQLGEKFRIELDIEPTID 268
G +++LD+ T+ K+DLE Q E+L+EE ++LK NH++E+ L Q +E+++ P D
Sbjct: 259 GLRQVLDNLTMEKSDLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKD 318
Query: 269 LNRVLGEMRAQYEAMVETNHQDVEQWFQAQSEGISLQAMSCSEELQCCQSEILELRCTVN 328
L + L +MR +YE ++ N +D+E ++ Q I + S +E+Q E+ +LR V
Sbjct: 319 LTKTLNDMRQEYEQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQ 378
Query: 329 ALEVERQAQHTLKDCLQNSLCEAEDRYGTELAQMQSLISNLEEQLSEIRADLERQNQEYQ 388
LE+E Q+Q + K L+ SL + ++RY +L +Q ISNLE Q++++R ++E QNQEY
Sbjct: 379 ELEIELQSQLSKKAALEKSLEDTKNRYCGQLQMIQEQISNLEAQITDVRQEIECQNQEYS 438
Query: 389 VLLDVKARLENEIATYRNLLESEDCKLPCNPCSTPASCTSCPSCGPVTGGSPSGHGASMG 448
+LL +K RLE EI TY NLLE + S G GS G G S G
Sbjct: 439 LLLSIKMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYG 498
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,042,403
Number of Sequences: 37866
Number of extensions: 778405
Number of successful extensions: 6439
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 176
Number of HSP's successfully gapped in prelim test: 477
Number of HSP's that attempted gapping in prelim test: 4733
Number of HSP's gapped (non-prelim): 1643
length of query: 449
length of database: 18,247,518
effective HSP length: 106
effective length of query: 343
effective length of database: 14,233,722
effective search space: 4882166646
effective search space used: 4882166646
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.