Search of human proteins with 5454014

Search of human proteins with 5454014

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5454014 tripartite motif-containing 38 [Homo sapiens]
         (465 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5454014 tripartite motif-containing 38 [Homo sapiens]              967   0.0  
gi|15208660 tripartite motif protein 21 [Homo sapiens]                350   2e-96
gi|112421127 tripartite motif-containing 58 [Homo sapiens]            350   2e-96
gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]   327   1e-89
gi|21630277 tripartite motif-containing 11 [Homo sapiens]             315   7e-86
gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]   313   3e-85
gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]    295   5e-80
gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]    295   5e-80
gi|37622899 ring finger protein 137 [Homo sapiens]                    294   1e-79
gi|5730009 ret finger protein [Homo sapiens]                          287   1e-77
gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]   262   4e-70
gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]    262   4e-70
gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]      256   2e-68
gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]      256   2e-68
gi|51477690 tripartite motif-containing 6 and tripartite motif-c...   256   2e-68
gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo s...   256   4e-68
gi|117938316 tripartite motif-containing 22 [Homo sapiens]            247   1e-65
gi|157426898 tripartite motif-containing 10 isoform 1 [Homo sapi...   240   2e-63
gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo sa...   234   1e-61
gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]   234   2e-61
gi|22749269 ring finger protein 129 [Homo sapiens]                    230   2e-60
gi|157743261 tripartite motif-containing 75 [Homo sapiens]            228   7e-60
gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]    227   2e-59
gi|149193331 tripartite motif protein 15 [Homo sapiens]               222   6e-58
gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo s...   220   2e-57
gi|31542779 tripartite motif family-like 1 [Homo sapiens]             217   2e-56
gi|4508005 tripartite motif-containing 26 [Homo sapiens]              211   1e-54
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]   205   8e-53
gi|4557743 Mediterranean fever protein [Homo sapiens]                 197   2e-50
gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]   193   2e-49

>gi|5454014 tripartite motif-containing 38 [Homo sapiens]
          Length = 465

 Score =  967 bits (2501), Expect = 0.0
 Identities = 465/465 (100%), Positives = 465/465 (100%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP
Sbjct: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQ 120
           QCRAPFHMDSLRPNKQLGSLIEALKETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQ
Sbjct: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQ 120

Query: 121 HKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIR 180
           HKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIR
Sbjct: 121 HKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIR 180

Query: 181 SDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGS 240
           SDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGS
Sbjct: 181 SDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGS 240

Query: 241 AQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDT 300
           AQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDT
Sbjct: 241 AQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDT 300

Query: 301 AHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWD 360
           AHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWD
Sbjct: 301 AHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWD 360

Query: 361 LGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEA 420
           LGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEA
Sbjct: 361 LGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEA 420

Query: 421 GVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD 465
           GVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD
Sbjct: 421 GVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPGD 465


>gi|15208660 tripartite motif protein 21 [Homo sapiens]
          Length = 475

 Score =  350 bits (898), Expect = 2e-96
 Identities = 194/458 (42%), Positives = 272/458 (59%), Gaps = 20/458 (4%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           MAS      M EE TC ICL     PVSI CGHS+C  CI+   K             CP
Sbjct: 1   MASAARLTMMWEEVTCPICLDPFVEPVSIECGHSFCQECISQVGKGGGS--------VCP 52

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICW 113
            CR  F + +LRPN+QL +++  LKE  QE         C  HGE+ HLFCE +G+ +CW
Sbjct: 53  VCRQRFLLKNLRPNRQLANMVNNLKEISQEAREGTQGERCAVHGERLHLFCEKDGKALCW 112

Query: 114 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ 173
            C ++ +H+ H    +E+  Q Y+EKLQ A+ +L++ ++   + ++  A++   WK+ V+
Sbjct: 113 VCAQSRKHRDHAMVPLEEAAQEYQEKLQVALGELRRKQELAEKLEVEIAIKRADWKKTVE 172

Query: 174 IQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILEL 233
            Q+ +I ++F   + FL EEE+  L  LEK+E++ L  L + EA L  +S  L+  I EL
Sbjct: 173 TQKSRIHAEFVQQKNFLVEEEQRQLQELEKDEREQLRILGEKEAKLAQQSQALQELISEL 232

Query: 234 EEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVS 293
           + +C  SA +LLQ V   L RS +  L+  +  S EL ++C+V  L    KKMLR+  V 
Sbjct: 233 DRRCHSSALELLQEVIIVLERSESWNLKDLDITSPELRSVCHVPGL----KKMLRTCAVH 288

Query: 294 VTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDV 353
           +TLDPDTA+  LILSEDRRQV  G TQ++   +  RF ++P VLG + F SG+ Y+EVDV
Sbjct: 289 ITLDPDTANPWLILSEDRRQVRLGDTQQSIPGNEERFDSYPMVLGAQHFHSGKHYWEVDV 348

Query: 354 GEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVG 413
                WDLGVC ++V+R        +SGFWT+ L  K+ Y A T P T LHL   P  VG
Sbjct: 349 TGKEAWDLGVCRDSVRRKGHFLLSSKSGFWTIWLWNKQKYEAGTYPQTPLHLQVPPCQVG 408

Query: 414 IFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYF 450
           IFLDYEAG+VSFYN  + G  I++F + +F+  LRP+F
Sbjct: 409 IFLDYEAGMVSFYNITDHGSLIYSFSECAFTGPLRPFF 446


>gi|112421127 tripartite motif-containing 58 [Homo sapiens]
          Length = 486

 Score =  350 bits (898), Expect = 2e-96
 Identities = 190/468 (40%), Positives = 268/468 (57%), Gaps = 14/468 (2%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           MA     +++ E+A C +CL  +  PVS++CGHS+C  CI++F +     Q     + CP
Sbjct: 1   MAWAPPGERLREDARCPVCLDFLQEPVSVDCGHSFCLRCISEFCEKSDGAQ--GGVYACP 58

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS-----CEEHGEQFHLFCEDEGQLICWRC 115
           QCR PF     RPN+QL  L+E+++            C  HGE    FCE++   +CW C
Sbjct: 59  QCRGPFRPSGFRPNRQLAGLVESVRRLGLGAGPGARRCARHGEDLSRFCEEDEAALCWVC 118

Query: 116 ERAPQHKGHTTALVEDVCQGYKEKLQKAVTKL-KQLEDRCTEQKLSTAMRITKWKEKVQI 174
           +  P+H+ H TA +++    Y+ KLQ A+  + K+LED  T Q+ +   +   WKEKV++
Sbjct: 119 DAGPEHRTHRTAPLQEAAGSYQVKLQMALELMRKELEDALT-QEANVGKKTVIWKEKVEM 177

Query: 175 QRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELE 234
           QRQ+ R +F+  + FL +EE+  L RLE EE+ TL RLR+ ++ L  +S  LK    EL+
Sbjct: 178 QRQRFRLEFEKHRGFLAQEEQRQLRRLEAEERATLQRLRESKSRLVQQSKALKELADELQ 237

Query: 235 EKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSV 294
           E+CQ  A  LL+ V   LSRS AV    +E + +EL T C +       +++LR  QV V
Sbjct: 238 ERCQRPALGLLEGVRGVLSRSKAVTRLEAENIPMELKTACCIPGR----RELLRKFQVDV 293

Query: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVG 354
            LDP TAH  L+L+ D R V  G    +   +  RF  +PC+LG + F+SGR Y+EV VG
Sbjct: 294 KLDPATAHPSLLLTADLRSVQDGEPWRDVPNNPERFDTWPCILGLQSFSSGRHYWEVLVG 353

Query: 355 EGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGI 414
           EG  W LGVC + + R       P++G W L L K   Y+ L SP   L   E P  +GI
Sbjct: 354 EGAEWGLGVCQDTLPRKGETTPSPENGVWALWLLKGNEYMVLASPSVPLLQLESPRCIGI 413

Query: 415 FLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPP 462
           FLDYEAG +SFYN   G +I+TF +  FS  LRPYF +   +PL LPP
Sbjct: 414 FLDYEAGEISFYNVTDGSYIYTFNQL-FSGLLRPYFFICDATPLILPP 460


>gi|25777698 tripartite motif-containing 39 isoform 2 [Homo sapiens]
          Length = 488

 Score =  327 bits (838), Expect = 1e-89
 Identities = 192/483 (39%), Positives = 271/483 (56%), Gaps = 26/483 (5%)

Query: 2   ASTTSTKKMME----EATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETF 57
           AS  ST   +E    EA+CS+CL  +  PV I CGH++C  CIT ++++       +  F
Sbjct: 11  ASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWED------LERDF 64

Query: 58  CCPQCRAPFHMDSLRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQL 110
            CP CR      SLRPN+QLGS++E  K+          E  C +H E   LFC ++ + 
Sbjct: 65  PCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEA 124

Query: 111 ICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKE 170
           +C  C  +  H+ HT   ++D  Q YKEKLQK +  L+Q     T  K S   +  + K 
Sbjct: 125 VCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKR 184

Query: 171 KVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHI 230
            V+ +RQ+I  +F+ L   L EE++  L RLE+EEQ  L RLR+  A LG K  +L    
Sbjct: 185 LVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLA 244

Query: 231 LELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELH-TMCNVSKLYFDVKKMLRS 289
            E+E KC  S  ++L++V  TL +   VK     +VS+EL     N  + YF ++K+L+ 
Sbjct: 245 AEVEGKCLQSGFEMLKDVKSTLEKCEKVKTMEVTSVSIELEKNFSNFPRQYFALRKILKQ 304

Query: 290 HQVSVTLDPDTAHHELILSEDRRQVTRGYTQ-ENQDTSSRRFTAFPCVLGCEGFTSGRRY 348
               VTLDP+TAH  L+LSEDR+ V    T+  +   + RRFT +PCVL  EGFTSGR Y
Sbjct: 305 LIADVTLDPETAHPNLVLSEDRKSVKFVETRLRDLPDTPRRFTFYPCVLATEGFTSGRHY 364

Query: 349 FEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQ 408
           +EV+VG+ T W +GVC ++V R   +   P++G+W +RL     Y A T+P T LH+  +
Sbjct: 365 WEVEVGDKTHWAVGVCRDSVSRKGELTPLPETGYWRVRLWNGDKYAATTTPFTPLHIKVK 424

Query: 409 PLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQV------YQYSPLFLPP 462
           P  VGIFLDYEAG +SFYN     HI+TF   +F++ L P F           +PL + P
Sbjct: 425 PKRVGIFLDYEAGTLSFYNVTDRSHIYTFTD-TFTEKLWPLFYPGIRAGRKNAAPLTIRP 483

Query: 463 PGD 465
           P D
Sbjct: 484 PTD 486


>gi|21630277 tripartite motif-containing 11 [Homo sapiens]
          Length = 468

 Score =  315 bits (806), Expect = 7e-86
 Identities = 189/463 (40%), Positives = 253/463 (54%), Gaps = 20/463 (4%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           MA+   +  + EEATC+ICL   T+PV  +CGH++C  CI   +  P      +  + CP
Sbjct: 1   MAAPDLSTNLQEEATCAICLDYFTDPVMTDCGHNFCRECIRRCWGQP------EGPYACP 54

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS-----CEEHGEQFHLFCEDEGQLICWRC 115
           +CR      +LRPN+ L  + E  +            C  H E    FC DE +L+C  C
Sbjct: 55  ECRELSPQRNLRPNRPLAKMAEMARRLHPPSPVPQGVCPAHREPLAAFCGDELRLLCAAC 114

Query: 116 ERAPQHKGHTTALVEDVCQGYKEKLQKAVTKL-KQLEDRCTEQKLSTAMRITKWKEKVQI 174
           ER+ +H  H    ++D  +  K KL+K++  L KQ++D    Q  +    +  W++ V+ 
Sbjct: 115 ERSGEHWAHRVRPLQDAAEDLKAKLEKSLEHLRKQMQDALLFQAQADETCVL-WQKMVES 173

Query: 175 QRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELE 234
           QRQ +  +F+ L+  L EEE+  L RLE+EE + L RLR+  A LG +S  L   I ELE
Sbjct: 174 QRQNVLGEFERLRRLLAEEEQQLLQRLEEEELEVLPRLREGAAHLGQQSAHLAELIAELE 233

Query: 235 EKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVSV 294
            +CQ  A  LLQ++ D L R   VKL+  E V +EL T+C V  L     + LR  +  V
Sbjct: 234 GRCQLPALGLLQDIKDALRRVQDVKLQPPEVVPMELRTVCRVPGLV----ETLRRFRGDV 289

Query: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVG 354
           TLDPDTA+ ELILSEDRR V RG  ++    S  RF   PCVLG E FTSGR Y+EV+VG
Sbjct: 290 TLDPDTANPELILSEDRRSVQRGDLRQALPDSPERFDPGPCVLGQERFTSGRHYWEVEVG 349

Query: 355 EGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGI 414
           + T W LGVC ENV R    +    +GFW L      G    +S      L + P  VGI
Sbjct: 350 DRTSWALGVCRENVNRKEKGELSAGNGFWILVFL---GSYYNSSERALAPLRDPPRRVGI 406

Query: 415 FLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSP 457
           FLDYEAG +SFY+   G  +F FP+  FS TLRP F     SP
Sbjct: 407 FLDYEAGHLSFYSATDGSLLFIFPEIPFSGTLRPLFSPLSSSP 449


>gi|25777696 tripartite motif-containing 39 isoform 1 [Homo sapiens]
          Length = 518

 Score =  313 bits (801), Expect = 3e-85
 Identities = 193/513 (37%), Positives = 275/513 (53%), Gaps = 56/513 (10%)

Query: 2   ASTTSTKKMME----EATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETF 57
           AS  ST   +E    EA+CS+CL  +  PV I CGH++C  CIT ++++       +  F
Sbjct: 11  ASAASTAAALENLQVEASCSVCLEYLKEPVIIECGHNFCKACITRWWED------LERDF 64

Query: 58  CCPQCRAPFHMDSLRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQL 110
            CP CR      SLRPN+QLGS++E  K+          E  C +H E   LFC ++ + 
Sbjct: 65  PCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQAVKRKIRDESLCPQHHEALSLFCYEDQEA 124

Query: 111 ICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKE 170
           +C  C  +  H+ HT   ++D  Q YKEKLQK +  L+Q     T  K S   +  + K 
Sbjct: 125 VCLICAISHTHRAHTVVPLDDATQEYKEKLQKCLEPLEQKLQEITRCKSSEEKKPGELKR 184

Query: 171 KVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHI 230
            V+ +RQ+I  +F+ L   L EE++  L RLE+EEQ  L RLR+  A LG K  +L    
Sbjct: 185 LVESRRQQILREFEELHRRLDEEQQVLLSRLEEEEQDILQRLRENAAHLGDKRRDLAHLA 244

Query: 231 LELEEKCQGSAQKLLQNVNDTLSRSW----------------------------AVKLET 262
            E+E KC  S  ++L++V  TL ++                               K++T
Sbjct: 245 AEVEGKCLQSGFEMLKDVKSTLEKNIPRKFGGSLSTICPRDHKALLGLVKEINRCEKVKT 304

Query: 263 SE--AVSLELH-TMCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYT 319
            E  +VS+EL     N  + YF ++K+L+     VTLDP+TAH  L+LSEDR+ V    T
Sbjct: 305 MEVTSVSIELEKNFSNFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVET 364

Query: 320 Q-ENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEP 378
           +  +   + RRFT +PCVL  EGFTSGR Y+EV+VG+ T W +GVC ++V R   +   P
Sbjct: 365 RLRDLPDTPRRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTPLP 424

Query: 379 QSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFP 438
           ++G+W +RL     Y A T+P T LH+  +P  VGIFLDYEAG +SFYN     HI+TF 
Sbjct: 425 ETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHIYTFT 484

Query: 439 KASFSDTLRPYFQV------YQYSPLFLPPPGD 465
             +F++ L P F           +PL + PP D
Sbjct: 485 D-TFTEKLWPLFYPGIRAGRKNAAPLTIRPPTD 516


>gi|18079262 tripartite motif-containing 6 isoform 2 [Homo sapiens]
          Length = 488

 Score =  295 bits (756), Expect = 5e-80
 Identities = 177/471 (37%), Positives = 263/471 (55%), Gaps = 41/471 (8%)

Query: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE-TFCCPQCRAPFHMDS 70
           EE TC ICL L+T P+SI+CGHS+C  CIT    N  +  + QE    CP C+  +   +
Sbjct: 11  EEVTCPICLELLTEPLSIDCGHSFCQACITP---NGRESVIGQEGERSCPVCQTSYQPGN 67

Query: 71  LRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKG 123
           LRPN+ L +++  L+E         + + C +HGE+  LFC+++G++ICW CER+ +H+G
Sbjct: 68  LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 127

Query: 124 HTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183
           H T LVE+V Q Y+EK Q+++ KLK  E    +       + T WK +++ +R +I+++F
Sbjct: 128 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 187

Query: 184 KNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQK 243
             L+  L   E+  L +LE+EE++ L  + + E  L  ++  L+  I +LE +CQGS  +
Sbjct: 188 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 247

Query: 244 LLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLR---------SHQVSV 294
           LLQ+V+D   RS    L   EA+  +L +M        D+K+MLR         S+ V V
Sbjct: 248 LLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAP----DLKRMLRVCRELTDVQSYWVDV 303

Query: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC-VLGCEGFTSGRRYFEVDV 353
           TL+P TA+  L+L+++RRQV   +        S     + C VLG + F+SG+ Y+EVDV
Sbjct: 304 TLNPHTANLNLVLAKNRRQVR--FVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDV 361

Query: 354 GEGTGWDLGVCMENV-----------QRGTGMKQEPQSGFWTLRLCKKKGYVAL--TSPP 400
            + T W LGVC  ++                 + +PQSG+W + L     Y A   +SP 
Sbjct: 362 AKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPS 421

Query: 401 TSLHLHEQPLLVGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYF 450
             L +   P  VG+FLDYEAG VSFYN  N G  I+TF K  F  TL PYF
Sbjct: 422 LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 472


>gi|51477692 tripartite motif-containing 6 isoform 1 [Homo sapiens]
          Length = 516

 Score =  295 bits (756), Expect = 5e-80
 Identities = 177/471 (37%), Positives = 263/471 (55%), Gaps = 41/471 (8%)

Query: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE-TFCCPQCRAPFHMDS 70
           EE TC ICL L+T P+SI+CGHS+C  CIT    N  +  + QE    CP C+  +   +
Sbjct: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITP---NGRESVIGQEGERSCPVCQTSYQPGN 95

Query: 71  LRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKG 123
           LRPN+ L +++  L+E         + + C +HGE+  LFC+++G++ICW CER+ +H+G
Sbjct: 96  LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155

Query: 124 HTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183
           H T LVE+V Q Y+EK Q+++ KLK  E    +       + T WK +++ +R +I+++F
Sbjct: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215

Query: 184 KNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQK 243
             L+  L   E+  L +LE+EE++ L  + + E  L  ++  L+  I +LE +CQGS  +
Sbjct: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275

Query: 244 LLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLR---------SHQVSV 294
           LLQ+V+D   RS    L   EA+  +L +M        D+K+MLR         S+ V V
Sbjct: 276 LLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAP----DLKRMLRVCRELTDVQSYWVDV 331

Query: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC-VLGCEGFTSGRRYFEVDV 353
           TL+P TA+  L+L+++RRQV   +        S     + C VLG + F+SG+ Y+EVDV
Sbjct: 332 TLNPHTANLNLVLAKNRRQVR--FVGAKVSGPSCLEKHYDCSVLGSQHFSSGKHYWEVDV 389

Query: 354 GEGTGWDLGVCMENV-----------QRGTGMKQEPQSGFWTLRLCKKKGYVAL--TSPP 400
            + T W LGVC  ++                 + +PQSG+W + L     Y A   +SP 
Sbjct: 390 AKKTAWILGVCSNSLGPTFSFNHFAQNHSAYSRYQPQSGYWVIGLQHNHEYRAYEDSSPS 449

Query: 401 TSLHLHEQPLLVGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYF 450
             L +   P  VG+FLDYEAG VSFYN  N G  I+TF K  F  TL PYF
Sbjct: 450 LLLSMTVPPRRVGVFLDYEAGTVSFYNVTNHGFPIYTFSKYYFPTTLCPYF 500


>gi|37622899 ring finger protein 137 [Homo sapiens]
          Length = 485

 Score =  294 bits (753), Expect = 1e-79
 Identities = 165/468 (35%), Positives = 262/468 (55%), Gaps = 24/468 (5%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           M  T   + ++EE  C IC++ +  P+SI+CGHS+CH C++  ++ P + Q     + CP
Sbjct: 1   MDPTALVEAIVEEVACPICMTFLREPMSIDCGHSFCHSCLSGLWEIPGESQ--NWGYTCP 58

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICW 113
            CRAP    +LRPN QL +++E ++              CE HGE+  +FC+++  ++C 
Sbjct: 59  LCRAPVQPRNLRPNWQLANVVEKVRLLRLHPGMGLKGDLCERHGEKLKMFCKEDVLIMCE 118

Query: 114 RCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQ 173
            C ++P+H+ H+   +EDV   YK +L +A+  LK+ ++   + ++    R   WK +V+
Sbjct: 119 ACSQSPEHEAHSVVPMEDVAWEYKWELHEALEHLKKEQEEAWKLEVGERKRTATWKIQVE 178

Query: 174 IQRQKIRSDFKNLQCFLHEEEKSY----------LWRLEKEEQQTLSRLRDYEAGLGLKS 223
            ++Q I  +F+  Q  L +++  +          L  L++E  +T+ +L    + L  +S
Sbjct: 179 TRKQSIVWEFEKYQRLLEKKQPPHRQLGAEVAAALASLQREAAETMQKLELNHSELIQQS 238

Query: 224 NELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDV 283
             L   I EL+E+ Q   + +LQ++ + L+RS +  L+  E +SLEL T C V  L    
Sbjct: 239 QVLWRMIAELKERSQRPVRWMLQDIQEVLNRSKSWSLQQPEPISLELKTDCRVLGL---- 294

Query: 284 KKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFT 343
           +++L+++   V LDPDTA+  LI+SEDR++V  G T +    +  RF  +  VLG +  +
Sbjct: 295 REILKTYAADVRLDPDTAYSRLIVSEDRKRVHYGDTNQKLPDNPERFYRYNIVLGSQCIS 354

Query: 344 SGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSL 403
           SGR Y+EV+VG+ + W LGVC +NV R   +   P  GFW +RL K   Y A T     L
Sbjct: 355 SGRHYWEVEVGDRSEWGLGVCKQNVDRKEVVYLSPHYGFWVIRLRKGNEYRAGTDEYPIL 414

Query: 404 HLHEQPLLVGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYF 450
            L   P  VGIF+DYEA  +SFYN  + G HIFTFP+  F   L PYF
Sbjct: 415 SLPVPPRRVGIFVDYEAHDISFYNVTDCGSHIFTFPRYPFPGRLLPYF 462


>gi|5730009 ret finger protein [Homo sapiens]
          Length = 513

 Score =  287 bits (735), Expect = 1e-77
 Identities = 167/482 (34%), Positives = 255/482 (52%), Gaps = 36/482 (7%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           MAS +  + + +E TC +CL     P+ ++CGH+ C  C+   +         +    CP
Sbjct: 1   MASGSVAECLQQETTCPVCLQYFAEPMMLDCGHNICCACLARCWGTA------ETNVSCP 54

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS---------CEEHGEQFHLFCEDEGQLI 111
           QCR  F    +RPN+ L ++ + +K+   E           CE+H E   L+CE++   I
Sbjct: 55  QCRETFPQRHMRPNRHLANVTQLVKQLRTERPSGPGGEMGVCEKHREPLKLYCEEDQMPI 114

Query: 112 CWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEK 171
           C  C+R+ +H+GH+   +E+  +G+KE++Q  +  LK+++D    ++        +    
Sbjct: 115 CVVCDRSREHRGHSVLPLEEAVEGFKEQIQNQLDHLKRVKDLKKRRRAQGEQARAELLSL 174

Query: 172 VQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHIL 231
            Q++R+KI  +F+ L   L E E   L RLE+ +    + +           + L S I 
Sbjct: 175 TQMEREKIVWEFEQLYHSLKEHEYRLLARLEELDLAIYNSINGAITQFSCNISHLSSLIA 234

Query: 232 ELEEKCQGSAQKLLQNVNDTLSRSWAVKLE----TSEAVSLELHTMCN------------ 275
           +LEEK Q   ++LLQ++ DTLSR+  +++     T   +  ++H                
Sbjct: 235 QLEEKQQQPTRELLQDIGDTLSRAERIRIPEPWITPPDLQEKIHIFAQKCLFLTESLKQF 294

Query: 276 VSKLYFDVKKM--LRSHQ---VSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRF 330
             K+  D++K+  LR  Q   V VTLDPDTA+  LILS++ RQV   Y Q++   +  RF
Sbjct: 295 TEKMQSDMEKIQELREAQLYSVDVTLDPDTAYPSLILSDNLRQVRYSYLQQDLPDNPERF 354

Query: 331 TAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKK 390
             FPCVLG   F +GR Y+EV+VG+   W +GVC ++V R  G+   PQ+GFW + L   
Sbjct: 355 NLFPCVLGSPCFIAGRHYWEVEVGDKAKWTIGVCEDSVCRKGGVTSAPQNGFWAVSLWYG 414

Query: 391 KGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450
           K Y ALTSP T+L L      VGIFLDY+AG VSFYN    CH FTF  A+F   +RPYF
Sbjct: 415 KEYWALTSPMTALPLRTPLQRVGIFLDYDAGEVSFYNVTERCHTFTFSHATFCGPVRPYF 474

Query: 451 QV 452
            +
Sbjct: 475 SL 476


>gi|68160933 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  262 bits (670), Expect = 4e-70
 Identities = 156/460 (33%), Positives = 253/460 (55%), Gaps = 14/460 (3%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE---TF 57
           M +    +K+ EEATCSICL   T+PV   CGH++C  CI   ++    K+ R++   +F
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 58  CCPQCRAPFHMDSLRPNKQLGSLIEALKE---TDQEMSCEEHGEQFHLFCEDEGQLICWR 114
            CP+CR      +L PN+ L  + E  ++     ++  C+EH E   LFC+ +   IC  
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVV 120

Query: 115 CERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQI 174
           C  + +H+ H     E+  QGYK KL++ +  L++   R    +      + +W+ KV+ 
Sbjct: 121 CRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKE 180

Query: 175 QRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELE 234
           +R++I  +F+ +  +L EEE+  L  LE EE++T SRLR+  A L  + + L+  +L+LE
Sbjct: 181 RRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLE 240

Query: 235 EKCQGSAQKLLQNVNDTLSRSWAVKLETSE-AVSLELHTMCNVSKLYFDVKKMLRSHQVS 293
           E+      ++LQ++ + LSR   V ++  E A      T+C V        ++LR     
Sbjct: 241 ERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLED 296

Query: 294 VTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSR-RFTAFPCVLGCEGFTSGRRYFEV- 351
           V  D  +A+  L+L E R++   G + E     S+ RF A+PC +G   F+SGR Y+EV 
Sbjct: 297 VVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVG 356

Query: 352 -DVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPL 410
            ++     W LGVC +NV R   + + P++GFW ++L K   Y++  S  T + L E P 
Sbjct: 357 MNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPS 416

Query: 411 LVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450
            +GIFLD+EAG VSFY+ + G H+ T+ +A+F   L+P+F
Sbjct: 417 HMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFF 456


>gi|7705825 tripartite motif-containing 17 isoform 1 [Homo sapiens]
          Length = 477

 Score =  262 bits (670), Expect = 4e-70
 Identities = 156/460 (33%), Positives = 253/460 (55%), Gaps = 14/460 (3%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE---TF 57
           M +    +K+ EEATCSICL   T+PV   CGH++C  CI   ++    K+ R++   +F
Sbjct: 1   MEAVELARKLQEEATCSICLDYFTDPVMTTCGHNFCRACIQLSWEKARGKKGRRKRKGSF 60

Query: 58  CCPQCRAPFHMDSLRPNKQLGSLIEALKE---TDQEMSCEEHGEQFHLFCEDEGQLICWR 114
            CP+CR      +L PN+ L  + E  ++     ++  C+EH E   LFC+ +   IC  
Sbjct: 61  PCPECREMSPQRNLLPNRLLTKVAEMAQQHPGLQKQDLCQEHHEPLKLFCQKDQSPICVV 120

Query: 115 CERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQI 174
           C  + +H+ H     E+  QGYK KL++ +  L++   R    +      + +W+ KV+ 
Sbjct: 121 CRESREHRLHRVLPAEEAVQGYKLKLEEDMEYLREQITRTGNLQAREEQSLAEWQGKVKE 180

Query: 175 QRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELE 234
           +R++I  +F+ +  +L EEE+  L  LE EE++T SRLR+  A L  + + L+  +L+LE
Sbjct: 181 RRERIVLEFEKMNLYLVEEEQRLLQALETEEEETASRLRESVACLDRQGHSLELLLLQLE 240

Query: 235 EKCQGSAQKLLQNVNDTLSRSWAVKLETSE-AVSLELHTMCNVSKLYFDVKKMLRSHQVS 293
           E+      ++LQ++ + LSR   V ++  E A      T+C V        ++LR     
Sbjct: 241 ERSTQGPLQMLQDMKEPLSRKNNVSVQCPEVAPPTRPRTVCRVPGQI----EVLRGFLED 296

Query: 294 VTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSR-RFTAFPCVLGCEGFTSGRRYFEV- 351
           V  D  +A+  L+L E R++   G + E     S+ RF A+PC +G   F+SGR Y+EV 
Sbjct: 297 VVPDATSAYPYLLLYESRQRRYLGSSPEGSGFCSKDRFVAYPCAVGQTAFSSGRHYWEVG 356

Query: 352 -DVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPL 410
            ++     W LGVC +NV R   + + P++GFW ++L K   Y++  S  T + L E P 
Sbjct: 357 MNITGDALWALGVCRDNVSRKDRVPKCPENGFWVVQLSKGTKYLSTFSALTPVMLMEPPS 416

Query: 411 LVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450
            +GIFLD+EAG VSFY+ + G H+ T+ +A+F   L+P+F
Sbjct: 417 HMGIFLDFEAGEVSFYSVSDGSHLHTYSQATFPGPLQPFF 456


>gi|51477687 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  256 bits (655), Expect = 2e-68
 Identities = 166/491 (33%), Positives = 256/491 (52%), Gaps = 50/491 (10%)

Query: 10  MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69
           + EE TC ICL L+T P+S++CGHS C  CIT   K        + +  CP C   +  +
Sbjct: 9   VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSS--CPVCGISYSFE 66

Query: 70  SLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICWRCERAPQHK 122
            L+ N+ L +++E LKE             C+ HGE+  LFC+++ ++ICW CER+ +H+
Sbjct: 67  HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 126

Query: 123 GHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSD 182
           GH T L E+V +  +EKLQ  + +LK+ E+   + +       T WK +VQ +RQ+I+++
Sbjct: 127 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 186

Query: 183 FKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQ 242
           F  L+  L+ EE+  L RLE+EE++TL +  + E  L  +   ++  I ++E + Q S  
Sbjct: 187 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 246

Query: 243 KLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKL-----YFDVKKMLRSHQVSVTLD 297
           +LLQ+++  +  S   +L+  + VS +L T+ +   L      F     +R + V VTL+
Sbjct: 247 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 306

Query: 298 PDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC----VLGCEGFTSGRRYFEVDV 353
               +  L+LSED+RQV            S     F C    VLG + F+SG+ Y+EVDV
Sbjct: 307 SVNLNLNLVLSEDQRQVI-----------SVPIWPFQCYNYGVLGSQYFSSGKHYWEVDV 355

Query: 354 GEGTGWDLGVCMENVQR-------------GTGMKQEPQSGFWTLRLCKKKGY----VAL 396
            + T W LGV      R                 K  P  G+W + L  K  Y     +L
Sbjct: 356 SKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESL 415

Query: 397 TSPP--TSLHLHEQPLLVGIFLDYEAGVVSFYNGNT-GCHIFTFPKASFSDTLRPYFQVY 453
           +S P   +L +   P  VG+FLDYEAG+VSF+N  + G  I+ F K  FS  + PYF  +
Sbjct: 416 SSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPW 475

Query: 454 QY-SPLFLPPP 463
              +P+ L PP
Sbjct: 476 NCPAPMTLCPP 486


>gi|18087807 tripartite motif protein 34 isoform 1 [Homo sapiens]
          Length = 488

 Score =  256 bits (655), Expect = 2e-68
 Identities = 166/491 (33%), Positives = 256/491 (52%), Gaps = 50/491 (10%)

Query: 10  MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69
           + EE TC ICL L+T P+S++CGHS C  CIT   K        + +  CP C   +  +
Sbjct: 9   VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSS--CPVCGISYSFE 66

Query: 70  SLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICWRCERAPQHK 122
            L+ N+ L +++E LKE             C+ HGE+  LFC+++ ++ICW CER+ +H+
Sbjct: 67  HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 126

Query: 123 GHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSD 182
           GH T L E+V +  +EKLQ  + +LK+ E+   + +       T WK +VQ +RQ+I+++
Sbjct: 127 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 186

Query: 183 FKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQ 242
           F  L+  L+ EE+  L RLE+EE++TL +  + E  L  +   ++  I ++E + Q S  
Sbjct: 187 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 246

Query: 243 KLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKL-----YFDVKKMLRSHQVSVTLD 297
           +LLQ+++  +  S   +L+  + VS +L T+ +   L      F     +R + V VTL+
Sbjct: 247 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 306

Query: 298 PDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC----VLGCEGFTSGRRYFEVDV 353
               +  L+LSED+RQV            S     F C    VLG + F+SG+ Y+EVDV
Sbjct: 307 SVNLNLNLVLSEDQRQVI-----------SVPIWPFQCYNYGVLGSQYFSSGKHYWEVDV 355

Query: 354 GEGTGWDLGVCMENVQR-------------GTGMKQEPQSGFWTLRLCKKKGY----VAL 396
            + T W LGV      R                 K  P  G+W + L  K  Y     +L
Sbjct: 356 SKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESL 415

Query: 397 TSPP--TSLHLHEQPLLVGIFLDYEAGVVSFYNGNT-GCHIFTFPKASFSDTLRPYFQVY 453
           +S P   +L +   P  VG+FLDYEAG+VSF+N  + G  I+ F K  FS  + PYF  +
Sbjct: 416 SSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPW 475

Query: 454 QY-SPLFLPPP 463
              +P+ L PP
Sbjct: 476 NCPAPMTLCPP 486


>gi|51477690 tripartite motif-containing 6 and tripartite
           motif-containing 34 [Homo sapiens]
          Length = 842

 Score =  256 bits (655), Expect = 2e-68
 Identities = 166/491 (33%), Positives = 256/491 (52%), Gaps = 50/491 (10%)

Query: 10  MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69
           + EE TC ICL L+T P+S++CGHS C  CIT   K        + +  CP C   +  +
Sbjct: 363 VQEEVTCPICLELLTEPLSLDCGHSLCRACITVSNKEAVTSMGGKSS--CPVCGISYSFE 420

Query: 70  SLRPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICWRCERAPQHK 122
            L+ N+ L +++E LKE             C+ HGE+  LFC+++ ++ICW CER+ +H+
Sbjct: 421 HLQANQHLANIVERLKEVKLSPDNGKKRDLCDHHGEKLLLFCKEDRKVICWLCERSQEHR 480

Query: 123 GHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSD 182
           GH T L E+V +  +EKLQ  + +LK+ E+   + +       T WK +VQ +RQ+I+++
Sbjct: 481 GHHTVLTEEVFKECQEKLQAVLKRLKKEEEEAEKLEADIREEKTSWKYQVQTERQRIQTE 540

Query: 183 FKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQ 242
           F  L+  L+ EE+  L RLE+EE++TL +  + E  L  +   ++  I ++E + Q S  
Sbjct: 541 FDQLRSILNNEEQRELQRLEEEEKKTLDKFAEAEDELVQQKQLVRELISDVECRSQWSTM 600

Query: 243 KLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKL-----YFDVKKMLRSHQVSVTLD 297
           +LLQ+++  +  S   +L+  + VS +L T+ +   L      F     +R + V VTL+
Sbjct: 601 ELLQDMSGIMKWSEIWRLKKPKMVSKKLKTVFHAPDLSRMLQMFRELTAVRCYWVDVTLN 660

Query: 298 PDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPC----VLGCEGFTSGRRYFEVDV 353
               +  L+LSED+RQV            S     F C    VLG + F+SG+ Y+EVDV
Sbjct: 661 SVNLNLNLVLSEDQRQVI-----------SVPIWPFQCYNYGVLGSQYFSSGKHYWEVDV 709

Query: 354 GEGTGWDLGVCMENVQR-------------GTGMKQEPQSGFWTLRLCKKKGY----VAL 396
            + T W LGV      R                 K  P  G+W + L  K  Y     +L
Sbjct: 710 SKKTAWILGVYCRTYSRHMKYVVRRCANRQNLYTKYRPLFGYWVIGLQNKCKYGVFEESL 769

Query: 397 TSPP--TSLHLHEQPLLVGIFLDYEAGVVSFYNGNT-GCHIFTFPKASFSDTLRPYFQVY 453
           +S P   +L +   P  VG+FLDYEAG+VSF+N  + G  I+ F K  FS  + PYF  +
Sbjct: 770 SSDPEVLTLSMAVPPCRVGVFLDYEAGIVSFFNVTSHGSLIYKFSKCCFSQPVYPYFNPW 829

Query: 454 QY-SPLFLPPP 463
              +P+ L PP
Sbjct: 830 NCPAPMTLCPP 840



 Score =  199 bits (507), Expect = 3e-51
 Identities = 106/285 (37%), Positives = 168/285 (58%), Gaps = 15/285 (5%)

Query: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQE-TFCCPQCRAPFHMDS 70
           EE TC ICL L+T P+SI+CGHS+C  CIT    N  +  + QE    CP C+  +   +
Sbjct: 39  EEVTCPICLELLTEPLSIDCGHSFCQACITP---NGRESVIGQEGERSCPVCQTSYQPGN 95

Query: 71  LRPNKQLGSLIEALKETD-------QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKG 123
           LRPN+ L +++  L+E         + + C +HGE+  LFC+++G++ICW CER+ +H+G
Sbjct: 96  LRPNRHLANIVRRLREVVLGPGKQLKAVLCADHGEKLQLFCQEDGKVICWLCERSQEHRG 155

Query: 124 HTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183
           H T LVE+V Q Y+EK Q+++ KLK  E    +       + T WK +++ +R +I+++F
Sbjct: 156 HHTFLVEEVAQEYQEKFQESLKKLKNEEQEAEKLTAFIREKKTSWKNQMEPERCRIQTEF 215

Query: 184 KNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQK 243
             L+  L   E+  L +LE+EE++ L  + + E  L  ++  L+  I +LE +CQGS  +
Sbjct: 216 NQLRNILDRVEQRELKKLEQEEKKGLRIIEEAENDLVHQTQSLRELISDLERRCQGSTME 275

Query: 244 LLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLR 288
           LLQ+V+D   RS    L   EA+  +L +M        D+K+MLR
Sbjct: 276 LLQDVSDVTERSEFWTLRKPEALPTKLRSMFRAP----DLKRMLR 316


>gi|14719418 tripartite motif protein TRIM5 isoform alpha [Homo
           sapiens]
          Length = 493

 Score =  256 bits (653), Expect = 4e-68
 Identities = 159/478 (33%), Positives = 243/478 (50%), Gaps = 52/478 (10%)

Query: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSL 71
           EE TC ICL L+T P+S++CGHS+C  C+T    N  +  L +    CP CR  +  +++
Sbjct: 11  EEVTCPICLELLTQPLSLDCGHSFCQACLT---ANHKKSMLDKGESSCPVCRISYQPENI 67

Query: 72  RPNKQLGSLIEALKETDQEMS------CEEHGEQFHLFCEDEGQLICWRCERAPQHKGHT 125
           RPN+ + +L+E L+E            C  HGE+  LFC+++G++ICW CER+ +H+GH 
Sbjct: 68  RPNRHVANLVEKLREVKLSPEGQKVDHCARHGEKLLLFCQEDGKVICWLCERSQEHRGHH 127

Query: 126 TALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKN 185
           T   E+V Q Y+ KLQ A+  L+Q +    E +         WK ++Q  +  + +DF+ 
Sbjct: 128 TFPTEEVAQEYQVKLQAALEMLRQKQQEAEELEADIREEKASWKTQIQYDKTNVLADFEQ 187

Query: 186 LQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLL 245
           L+  L  EE + L  LEKEE+  L  L + E  +  ++  L+  I +LE + QGS  +LL
Sbjct: 188 LRDILDWEESNELQNLEKEEEDILKSLTNSETEMVQQTQSLRELISDLEHRLQGSVMELL 247

Query: 246 QNVNDTLSRSWAVKLETSEAV---------SLELHTMCNVSKLYFDVKKMLRSHQVSVTL 296
           Q V+  + R+  V L+  E           + +L  M  V +   DV    R + V VT+
Sbjct: 248 QGVDGVIKRTENVTLKKPETFPKNQRRVFRAPDLKGMLEVFRELTDV----RRYWVDVTV 303

Query: 297 DPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAF------PCVLGCEGFTSGRRYFE 350
            P+      ++SED+RQV+    Q        R+  F        +LG +  TSG+ Y+E
Sbjct: 304 APNNISC-AVISEDKRQVSSPKPQIIYGARGTRYQTFVNFNYCTGILGSQSITSGKHYWE 362

Query: 351 VDVGEGTGWDLGVC-------MENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSL 403
           VDV + T W LGVC       M N+++      +P+ G+W + L  ++G        +S 
Sbjct: 363 VDVSKKTAWILGVCAGFQPDAMCNIEKNE--NYQPKYGYWVIGL--EEGVKCSAFQDSSF 418

Query: 404 HLHEQPLL-----------VGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPY 449
           H    P +           VG+FLDYEA  VSF+N  N G  I+ F   SFS  + PY
Sbjct: 419 HTPSVPFIVPLSVIICPDRVGVFLDYEACTVSFFNITNHGFLIYKFSHCSFSQPVFPY 476


>gi|117938316 tripartite motif-containing 22 [Homo sapiens]
          Length = 498

 Score =  247 bits (631), Expect = 1e-65
 Identities = 159/489 (32%), Positives = 252/489 (51%), Gaps = 40/489 (8%)

Query: 12  EEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSL 71
           +E TC ICL L+T P+S++CGHS+C  CIT   K      + +    CP C+  F   +L
Sbjct: 11  KEVTCPICLELLTEPLSLDCGHSFCQACITAKIKE--SVIISRGESSCPVCQTRFQPGNL 68

Query: 72  RPNKQLGSLIEALKETDQEMS-------CEEHGEQFHLFCEDEGQLICWRCERAPQHKGH 124
           RPN+ L +++E +KE             CE HG++  +FC+++G++ICW CE + +H+GH
Sbjct: 69  RPNRHLANIVERVKEVKMSPQEGQKRDVCEHHGKKLQIFCKEDGKVICWVCELSQEHQGH 128

Query: 125 TTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFK 184
            T  + +V +  +EKLQ A+ +L + +    + +       T WK  +QI+RQKI   F 
Sbjct: 129 QTFRINEVVKECQEKLQVALQRLIKEDQEAEKLEDDIRQERTAWKNYIQIERQKILKGFN 188

Query: 185 NLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKL 244
            ++  L  EE+  L +LE+ E   L  L      L  +  +  + I +L+ + +GS+ ++
Sbjct: 189 EMRVILDNEEQRELQKLEEGEVNVLDNLAAATDQLVQQRQDASTLISDLQRRLRGSSVEM 248

Query: 245 LQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKL--YFDVKKMLRSHQ---VSVTLDPD 299
           LQ+V D + RS +  L+  ++VS +L ++  V  L     V K L   Q   V V L+P 
Sbjct: 249 LQDVIDVMKRSESWTLKKPKSVSKKLKSVFRVPDLSGMLQVLKELTDVQYYWVDVMLNPG 308

Query: 300 TAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGW 359
           +A   + +S D+RQV    T   ++++   F+AF  V GC+ F+SG+ Y+EVDV     W
Sbjct: 309 SATSNVAISVDQRQVKTVRTCTFKNSNPCDFSAFG-VFGCQYFSSGKYYWEVDVSGKIAW 367

Query: 360 DLGVCME----NVQRGTGM-------------KQEPQSGFWTLRLCKKKGYVALTSPPTS 402
            LGV  +    N ++ +G              +  PQ G+W + L     Y A     +S
Sbjct: 368 ILGVHSKISSLNKRKSSGFAFDPSVNYSKVYSRYRPQYGYWVIGLQNTCEYNAFEDSSSS 427

Query: 403 ------LHLHEQPLLVGIFLDYEAGVVSFYN-GNTGCHIFTFPKASFSDTLRPYFQVYQ- 454
                 L +   P  +G+FLDYEAG+VSF+N  N G  I+ F    FS    PYF  +  
Sbjct: 428 DPKVLTLFMAVPPCRIGVFLDYEAGIVSFFNVTNHGALIYKFSGCRFSRPAYPYFNPWNC 487

Query: 455 YSPLFLPPP 463
             P+ + PP
Sbjct: 488 LVPMTVCPP 496


>gi|157426898 tripartite motif-containing 10 isoform 1 [Homo
           sapiens]
          Length = 481

 Score =  240 bits (612), Expect = 2e-63
 Identities = 154/480 (32%), Positives = 243/480 (50%), Gaps = 36/480 (7%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           MAS  S   + +E  C IC   +  PV+I+CGH++C  C+T + + P      +E+  CP
Sbjct: 1   MASAASVTSLADEVNCPICQGTLREPVTIDCGHNFCRACLTRYCEIPGPDL--EESPTCP 58

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETD--------QEMSCEEHGEQFHLFCEDEGQLIC 112
            C+ PF   S RPN QL +++E ++           +E  C+EHGE+ + FCED+   +C
Sbjct: 59  LCKEPFRPGSFRPNWQLANVVENIERLQLVSTLGLGEEDVCQEHGEKIYFFCEDDEMQLC 118

Query: 113 WRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKV 172
             C  A +H  HT   +ED    Y+E++ K +  L++  +   E +     R+     +V
Sbjct: 119 VVCREAGEHATHTMRFLEDAAAPYREQIHKCLKCLRKEREEIQEIQSRENKRMQVLLTQV 178

Query: 173 QIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILE 232
             +RQ++ S+F +L+ FL E++   L +LE ++   L +  +++  +  +     + I E
Sbjct: 179 STKRQQVISEFAHLRKFLEEQQSILLAQLESQDGDILRQRDEFDLLVAGEICRFSALIEE 238

Query: 233 LEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCN----------------V 276
           LEEK +  A++LL ++  TL R    K     AVS EL                     +
Sbjct: 239 LEEKNERPARELLTDIRSTLIRCETRKCRKPVAVSPELGQRIRDFPQQALPLQREMKMFL 298

Query: 277 SKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCV 336
            KL F+    L      ++LDP T+H +L+LSED ++    Y  +N   + +RF    CV
Sbjct: 299 EKLCFE----LDYEPAHISLDPQTSHPKLLLSEDHQRAQFSYKWQNSPDNPQRFDRATCV 354

Query: 337 LGCEGFTSGRRYF--EVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYV 394
           L   G T GR  +   +D+  G    +GV  E+VQR   ++  P+ G W +RL    G+V
Sbjct: 355 LAHTGITGGRHTWVVSIDLAHGGSCTVGVVSEDVQRKGELRLRPEEGVWAVRLA--WGFV 412

Query: 395 -ALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVY 453
            AL S PT L L EQP  V + LDYE G V+F N  T   I+TF  ASF+  + P+F ++
Sbjct: 413 SALGSFPTRLTLKEQPRQVRVSLDYEVGWVTFTNAVTREPIYTF-TASFTRKVIPFFGLW 471


>gi|15011941 tripartite motif protein TRIM4 isoform beta [Homo
           sapiens]
          Length = 474

 Score =  234 bits (597), Expect = 1e-61
 Identities = 161/481 (33%), Positives = 232/481 (48%), Gaps = 39/481 (8%)

Query: 10  MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69
           + EE TC ICL    +PVSI CGH++C  C+   +            F CP+CR P    
Sbjct: 6   IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP------FPCPECRHPSAPA 59

Query: 70  SLRPNKQLGSLIEALKETD----QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHT 125
           +LRPN  L  L E  +           C  H E   LFCED+ + +C  C  + +H+ H 
Sbjct: 60  ALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119

Query: 126 TALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKN 185
            A +++  + Y+EKL K+   L     +    +       T+WK+K++ QR +I ++F  
Sbjct: 120 MAPIDEAFESYREKLLKSQRNLVAKMKKVMHLQDVEVKNATQWKDKIKSQRMRISTEFSK 179

Query: 186 LQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLL 245
           L  FL EEE  +L RL KEE++T  +L +    L      LK  ILE+ EK Q    +LL
Sbjct: 180 LHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKLNQTIASLKKLILEVGEKSQAPTLELL 239

Query: 246 QNVNDTLSRSWAVKLETS-EAVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHE 304
           QN  + L+RS    +  S EAV ++  T+C +  +    K+ML+  QV+V L  DTAH +
Sbjct: 240 QNPKEVLTRSEIQDVNYSLEAVKVK--TVCQIPLM----KEMLKRFQVAVNLAEDTAHPK 293

Query: 305 LILSEDRRQVTR------------------GYTQENQDTSSRRFTAFPCVLGCEGFTSGR 346
           L+ S++ R V                    G+    +     RF   PCVLG   FTSG+
Sbjct: 294 LVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRNPQKTAFVERFQHLPCVLGKNVFTSGK 353

Query: 347 RYFEVDVGEGTGWDLGVCMENVQRGTG-MKQEPQSGFWTLRLCKKKGYVALTSPPTSLHL 405
            Y+EV+  +     +GVC E+V   T   K  P  G W +      GY  L   P +   
Sbjct: 354 HYWEVESRDSLEVAVGVCREDVMGITDRSKMSPDVGIWAI-YWSAAGYWPLIGFPGTPTQ 412

Query: 406 HEQPL-LVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQYSPLFLPPPG 464
            E  L  VG++LD   G VSFY+   G H+ TF  +S S  LRP+F +   + L +PP  
Sbjct: 413 QEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFSCSSVS-RLRPFFWLSPLASLVIPPVT 471

Query: 465 D 465
           D
Sbjct: 472 D 472


>gi|68160935 tripartite motif-containing 17 isoform 2 [Homo sapiens]
          Length = 450

 Score =  234 bits (596), Expect = 2e-61
 Identities = 142/430 (33%), Positives = 235/430 (54%), Gaps = 14/430 (3%)

Query: 31  CGHSYCHLCITDFFKNPSQKQLRQE---TFCCPQCRAPFHMDSLRPNKQLGSLIEALKE- 86
           CGH++C  CI   ++    K+ R++   +F CP+CR      +L PN+ L  + E  ++ 
Sbjct: 4   CGHNFCRACIQLSWEKARGKKGRRKRKGSFPCPECREMSPQRNLLPNRLLTKVAEMAQQH 63

Query: 87  --TDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAV 144
               ++  C+EH E   LFC+ +   IC  C  + +H+ H     E+  QGYK KL++ +
Sbjct: 64  PGLQKQDLCQEHHEPLKLFCQKDQSPICVVCRESREHRLHRVLPAEEAVQGYKLKLEEDM 123

Query: 145 TKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKE 204
             L++   R    +      + +W+ KV+ +R++I  +F+ +  +L EEE+  L  LE E
Sbjct: 124 EYLREQITRTGNLQAREEQSLAEWQGKVKERRERIVLEFEKMNLYLVEEEQRLLQALETE 183

Query: 205 EQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSE 264
           E++T SRLR+  A L  + + L+  +L+LEE+      ++LQ++ + LSR   V ++  E
Sbjct: 184 EEETASRLRESVACLDRQGHSLELLLLQLEERSTQGPLQMLQDMKEPLSRKNNVSVQCPE 243

Query: 265 -AVSLELHTMCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQ 323
            A      T+C V        ++LR     V  D  +A+  L+L E R++   G + E  
Sbjct: 244 VAPPTRPRTVCRVPGQI----EVLRGFLEDVVPDATSAYPYLLLYESRQRRYLGSSPEGS 299

Query: 324 DTSSR-RFTAFPCVLGCEGFTSGRRYFEV--DVGEGTGWDLGVCMENVQRGTGMKQEPQS 380
              S+ RF A+PC +G   F+SGR Y+EV  ++     W LGVC +NV R   + + P++
Sbjct: 300 GFCSKDRFVAYPCAVGQTAFSSGRHYWEVGMNITGDALWALGVCRDNVSRKDRVPKCPEN 359

Query: 381 GFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKA 440
           GFW ++L K   Y++  S  T + L E P  +GIFLD+EAG VSFY+ + G H+ T+ +A
Sbjct: 360 GFWVVQLSKGTKYLSTFSALTPVMLMEPPSHMGIFLDFEAGEVSFYSVSDGSHLHTYSQA 419

Query: 441 SFSDTLRPYF 450
           +F   L+P+F
Sbjct: 420 TFPGPLQPFF 429


>gi|22749269 ring finger protein 129 [Homo sapiens]
          Length = 471

 Score =  230 bits (586), Expect = 2e-60
 Identities = 142/460 (30%), Positives = 235/460 (51%), Gaps = 18/460 (3%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           M   T+   + EE++C ICL  + +PV+INCGH++C  C++  +K+        +TF CP
Sbjct: 1   MEFVTALVNLQEESSCPICLEYLKDPVTINCGHNFCRSCLSVSWKD------LDDTFPCP 54

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMS----------CEEHGEQFHLFCEDEGQL 110
            CR  F   S R N QL +L E  K+     S          CE+H +   LFC  + ++
Sbjct: 55  VCRFCFPYKSFRRNPQLRNLTEIAKQLQIRRSKRKRQKENAMCEKHNQFLTLFCVKDLEI 114

Query: 111 ICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKE 170
           +C +C  + +H+ H    ++     ++E L+ ++  L+   +R  +  +    +  + K+
Sbjct: 115 LCTQCSFSTKHQKHYICPIKKAASYHREILEGSLEPLRNNIERVEKVIILQGSKSVELKK 174

Query: 171 KVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHI 230
           KV+ +R++I S+F+ ++ FL  E++  L +++ EE   L++L +    L    + LK  +
Sbjct: 175 KVEYKREEINSEFEQIRLFLQNEQEMILRQIQDEEMNILAKLNENLVELSDYVSTLKHLL 234

Query: 231 LELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSH 290
            E+E K   S  +LL        +   +K     +  L  +   ++   Y  + ++++  
Sbjct: 235 REVEGKSVQSNLELLTQAKSMHHKYQNLKCPELFSFRLTKYGF-SLPPQYSGLDRIIKPF 293

Query: 291 QVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFE 350
           QV V LD +TAH +L++SEDR+ V     + N     RRF   P VLG + F+SGR Y+E
Sbjct: 294 QVDVILDLNTAHPQLLVSEDRKAVRYERKKRNICYDPRRFYVCPAVLGSQRFSSGRHYWE 353

Query: 351 VDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPL 410
           V+VG    W LGVC + + R    +     GFW +    K GYVA     T L    +P 
Sbjct: 354 VEVGNKPKWILGVCQDCLLRNWQDQPSVLGGFWAIGRYMKSGYVASGPKTTQLLPVVKPS 413

Query: 411 LVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450
            +GIFLDYE G +SFYN N    ++TF    F++ + PYF
Sbjct: 414 KIGIFLDYELGDLSFYNMNDRSILYTF-NDCFTEAVWPYF 452


>gi|157743261 tripartite motif-containing 75 [Homo sapiens]
          Length = 468

 Score =  228 bits (582), Expect = 7e-60
 Identities = 146/467 (31%), Positives = 242/467 (51%), Gaps = 30/467 (6%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           MA   +   +  EA CSICL  +++PV+I CGH++C  CI   + +       QE F CP
Sbjct: 1   MAVAAALTGLQAEAKCSICLDYLSDPVTIECGHNFCRSCIQQSWLD------LQELFPCP 54

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALK----------ETDQEMSCEEHGEQFHLFCEDEGQL 110
            CR        R N QLG +IE  K          + ++   CE+H +   +FC+++  +
Sbjct: 55  VCRHQCQEGHFRSNTQLGRMIEIAKLLQSTKSNKRKQEETTLCEKHNQPLSVFCKEDLMV 114

Query: 111 ICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLK-QLEDRCTEQKLST-AMRITKW 168
           +C  C + P H+GH    +E     Y+++    +  LK QL D   ++ +ST + +  + 
Sbjct: 115 LCPLCTQPPDHQGHHVRPIEKAAIHYRKRFCSYIQPLKKQLAD--LQKLISTQSKKPLEL 172

Query: 169 KEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKS 228
           +E V+ QRQ++ S+F++L  FL  E+++ L RL +EE+    +L          S  LKS
Sbjct: 173 REMVENQRQELSSEFEHLNQFLDREQQAVLSRLAEEEKDNQQKLSANITAFSNYSATLKS 232

Query: 229 HILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTM---CNVSKLYFDVKK 285
            + ++ E  + S  +LL  +       +  + E+S ++   +H     C+    Y  +++
Sbjct: 233 QLSKVVELSELSELELLSQIKIF----YESENESSPSI-FSIHLKRDGCSFPPQYSALQR 287

Query: 286 MLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSG 345
           +++  +V + LDP+TAH  LI+SED+++V     ++      +RFT  P VLG   F SG
Sbjct: 288 IIKKFKVEIILDPETAHPNLIVSEDKKRVRFTKRKQKVPGFPKRFTVKPVVLGFPYFHSG 347

Query: 346 RRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHL 405
           R ++E++VG+ + W +G+C +++          Q   W + L +  GY A  + PT L L
Sbjct: 348 RHFWEIEVGDKSEWAIGICKDSLPTKARRPSSAQQECWRIEL-QDDGYHAPGAFPTPLLL 406

Query: 406 HEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQV 452
             +   +GIFLDYE G +SFYN     HI TF   +F+  LRPYF V
Sbjct: 407 EVKARAIGIFLDYEMGEISFYNMAEKSHICTFTD-TFTGPLRPYFYV 452


>gi|44680122 tripartite motif-containing 7 isoform 1 [Homo sapiens]
          Length = 511

 Score =  227 bits (579), Expect = 2e-59
 Identities = 160/486 (32%), Positives = 238/486 (48%), Gaps = 49/486 (10%)

Query: 9   KMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFC------CPQC 62
           ++  EATCSICL L   PVS+ CGHS+C  CI   ++ P    +   T        CPQC
Sbjct: 22  ELQGEATCSICLELFREPVSVECGHSFCRACIGRCWERPGAGSVGAATRAPPFPLPCPQC 81

Query: 63  RAPFHMDSLRPNKQLGSLIEALKETDQEMS------------------CEEHGEQFHLFC 104
           R P     LRPN+QL ++   L+      +                  C +HGE F L+C
Sbjct: 82  REPARPSQLRPNRQLAAVATLLRRFSLPAAAPGEHGSQAAAARAAAARCGQHGEPFKLYC 141

Query: 105 EDEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKL-KQLED----RCTEQKL 159
           +D+G+ IC  C+RA +H+ H    +++  Q  KE L+  +  L K+LED    R TE+K 
Sbjct: 142 QDDGRAICVVCDRAREHREHAVLPLDEAVQEAKELLESRLRVLKKELEDCEVFRSTEKKE 201

Query: 160 STAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGL 219
           S  +      +++  +++K+ ++F+ L+ FL E+E   L RLE+  ++   +  +  A L
Sbjct: 202 SKEL-----LKQMAAEQEKVGAEFQALRAFLVEQEGRLLGRLEELSREVAQKQNENLAQL 256

Query: 220 GLKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLEL-HTMCNVSK 278
           G++  +L     +++E  Q      LQ    TLSR   V       VS E+ + + NVS 
Sbjct: 257 GVEITQLSKLSSQIQETAQKPDLDFLQEFKSTLSRCSNVPGPKPTTVSSEMKNKVWNVSL 316

Query: 279 LYFDVKKML------------RSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTS 326
             F +K ML            +  +V +TLDPDTA+  LILS D + V  G   ++    
Sbjct: 317 KTFVLKGMLKKFKEDLRGELEKEEKVELTLDPDTANPRLILSLDLKGVRLGERAQDLPNH 376

Query: 327 SRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLR 386
             RF     VL   GF+SGR ++EV+VG   GW  GV  E+V+R       P+ G W L+
Sbjct: 377 PCRFDTNTRVLASCGFSSGRHHWEVEVGSKDGWAFGVARESVRRKGLTPFTPEEGVWALQ 436

Query: 387 LCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTL 446
           L     Y A+TSP  S         V + LD E G VSFY      H++TF + +F + +
Sbjct: 437 L-NGGQYWAVTSPERSPLSCGHLSRVRVALDLEVGAVSFYAVEDMRHLYTF-RVNFQERV 494

Query: 447 RPYFQV 452
            P F V
Sbjct: 495 FPLFSV 500


>gi|149193331 tripartite motif protein 15 [Homo sapiens]
          Length = 465

 Score =  222 bits (565), Expect = 6e-58
 Identities = 145/468 (30%), Positives = 235/468 (50%), Gaps = 26/468 (5%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           M +T S K + E   C++C   + + V+I CGH++C LC+    +  +Q     +   CP
Sbjct: 1   MPATPSLKVVHELPACTLCAGPLEDAVTIPCGHTFCRLCLPALSQMGAQSS--GKILLCP 58

Query: 61  QCRAPFHMDSLRPNKQLGSLIEALKETDQEMSCEEHGEQFHLFCEDEGQLICWRCERAPQ 120
            C+     ++      LG L E          CEEHGE+ + FCE++ + +C  C   P 
Sbjct: 59  LCQEEEQAETPMAPVPLGPLGETY--------CEEHGEKIYFFCENDAEFLCVFCREGPT 110

Query: 121 HKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIR 180
           H+ HT   +++  Q Y+++L+  +  L    D   + K     ++     +++ ++ ++ 
Sbjct: 111 HQAHTVGFLDEAIQPYRDRLRSRLEALSTERDEIEDVKCQEDQKLQVLLTQIESKKHQVE 170

Query: 181 SDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQGS 240
           + F+ LQ  L ++    L RL + EQQ      +Y   +  +   L + + ELEEKCQ  
Sbjct: 171 TAFERLQQELEQQRCLLLARLRELEQQIWKERDEYITKVSEEVTRLGAQVKELEEKCQQP 230

Query: 241 AQKLLQNVNDTLSRSWAVKLETSEAVSLEL-HTMCNVSKLYFDVKKMLR------SHQVS 293
           A +LLQ+V    SR       + EA+S +L   + +  +    + +M+R      +H + 
Sbjct: 231 ASELLQDVRVNQSRCEMKTFVSPEAISPDLVKKIRDFHRKILTLPEMMRMFSENLAHHLE 290

Query: 294 -----VTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRY 348
                +TLDP TA   L+LSEDR+ V     +++   S  RF   P VLG  GF+SGR  
Sbjct: 291 IDSGVITLDPQTASRSLVLSEDRKSVRYTRQKKSLPDSPLRFDGLPAVLGFPGFSSGRHR 350

Query: 349 FEVD--VGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLH 406
           ++VD  +G+G G  +GV  E V+R   M    + G W + +  ++ + A TSP T L L 
Sbjct: 351 WQVDLQLGDGGGCTVGVAGEGVRRKGEMGLSAEDGVWAVIISHQQCW-ASTSPGTDLPLS 409

Query: 407 EQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYFQVYQ 454
           E P  V + LDYEAG V+ +N  T   IFTF  ASFS  + P+F V++
Sbjct: 410 EIPRGVRVALDYEAGQVTLHNAQTQEPIFTF-TASFSGKVFPFFAVWK 456


>gi|14670266 tripartite motif protein TRIM4 isoform alpha [Homo
           sapiens]
          Length = 500

 Score =  220 bits (560), Expect = 2e-57
 Identities = 161/507 (31%), Positives = 232/507 (45%), Gaps = 65/507 (12%)

Query: 10  MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMD 69
           + EE TC ICL    +PVSI CGH++C  C+   +            F CP+CR P    
Sbjct: 6   IQEELTCPICLDYFQDPVSIECGHNFCRGCLHRNWAPGGGP------FPCPECRHPSAPA 59

Query: 70  SLRPNKQLGSLIEALKETD----QEMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHT 125
           +LRPN  L  L E  +           C  H E   LFCED+ + +C  C  + +H+ H 
Sbjct: 60  ALRPNWALARLTEKTQRRRLGPVPPGLCGRHWEPLRLFCEDDQRPVCLVCRESQEHQTHA 119

Query: 126 TALVEDVCQGYK--------------------------EKLQKAVTKLKQLEDRCTEQKL 159
            A +++  + Y+                          EKL K+   L     +    + 
Sbjct: 120 MAPIDEAFESYRTGNFDIHVDEWKRRLIRLLLYHSKQEEKLLKSQRNLVAKMKKVMHLQD 179

Query: 160 STAMRITKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGL 219
                 T+WK+K++ QR +I ++F  L  FL EEE  +L RL KEE++T  +L +    L
Sbjct: 180 VEVKNATQWKDKIKSQRMRISTEFSKLHNFLVEEEDLFLQRLNKEEEETKKKLNENTLKL 239

Query: 220 GLKSNELKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETS-EAVSLELHTMCNVSK 278
                 LK  ILE+ EK Q    +LLQN  + L+RS    +  S EAV ++  T+C +  
Sbjct: 240 NQTIASLKKLILEVGEKSQAPTLELLQNPKEVLTRSEIQDVNYSLEAVKVK--TVCQIPL 297

Query: 279 LYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTR------------------GYTQ 320
           +    K+ML+  QV+V L  DTAH +L+ S++ R V                    G+  
Sbjct: 298 M----KEMLKRFQVAVNLAEDTAHPKLVFSQEGRYVKNTASASSWPVFSSAWNYFAGWRN 353

Query: 321 ENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTG-MKQEPQ 379
             +     RF   PCVLG   FTSG+ Y+EV+  +     +GVC E+V   T   K  P 
Sbjct: 354 PQKTAFVERFQHLPCVLGKNVFTSGKHYWEVESRDSLEVAVGVCREDVMGITDRSKMSPD 413

Query: 380 SGFWTLRLCKKKGYVALTSPPTSLHLHEQPL-LVGIFLDYEAGVVSFYNGNTGCHIFTFP 438
            G W +      GY  L   P +    E  L  VG++LD   G VSFY+   G H+ TF 
Sbjct: 414 VGIWAI-YWSAAGYWPLIGFPGTPTQQEPALHRVGVYLDRGTGNVSFYSAVDGVHLHTFS 472

Query: 439 KASFSDTLRPYFQVYQYSPLFLPPPGD 465
            +S S  LRP+F +   + L +PP  D
Sbjct: 473 CSSVS-RLRPFFWLSPLASLVIPPVTD 498


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score =  217 bits (553), Expect = 2e-56
 Identities = 140/461 (30%), Positives = 230/461 (49%), Gaps = 27/461 (5%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           M++    + + EE TC ICL   ++PV+  CGHS+C +C+   ++             CP
Sbjct: 1   MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEE------HNTPLSCP 54

Query: 61  QCRAPFHMDSLRPNKQLGSLI--------EALKETDQEMSCEEHGEQFHLFCEDE--GQL 110
           +C         + N++LG L         + L+  D++ S            +DE  G  
Sbjct: 55  ECWRTLEGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSA 114

Query: 111 ICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKE 170
                  A  H  +   L  +  + ++EKLQ+ +  L+               R+   +E
Sbjct: 115 FV-----AQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQE 169

Query: 171 KVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHI 230
           + +  +Q + S++  +  FL EEE+  L  LE+EE++ + +LR+ E  L  +   L   I
Sbjct: 170 ETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMI 229

Query: 231 LELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSH 290
            ++E   Q SA + L+ V   L RS  + L+  EA + EL ++C ++ +    K+MLR  
Sbjct: 230 AQIESSSQSSAFESLEEVRGALERSEPLLLQCPEATTTEL-SLCRITGM----KEMLRKF 284

Query: 291 QVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFE 350
              +TLDP TA+  L+LSED + V  G +++    +  RF     VLG + FTSGR Y+E
Sbjct: 285 STEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWE 344

Query: 351 VDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGY-VALTSPPTSLHLHEQP 409
           V+VG  T W++G+C ++V R   + + P   F  + L     Y + ++SP    H+ E  
Sbjct: 345 VEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPV 404

Query: 410 LLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450
             VG+FLDYE+G ++FYNG     I++FP+ASF + LRP F
Sbjct: 405 CKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIF 445


>gi|4508005 tripartite motif-containing 26 [Homo sapiens]
          Length = 539

 Score =  211 bits (537), Expect = 1e-54
 Identities = 162/534 (30%), Positives = 243/534 (45%), Gaps = 94/534 (17%)

Query: 1   MASTTSTKKMMEEATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCP 60
           MA++   + + EE TCSICL  + +PV+I+CGH +C  C TD       + +      CP
Sbjct: 1   MATSAPLRSLEEEVTCSICLDYLRDPVTIDCGHVFCRSCTTDVRPISGSRPV------CP 54

Query: 61  QCRAPFHMDSLRPNKQLGSLIEAL---------------KETDQEMSCEEHGEQFHLFCE 105
            C+ PF  +++RP  QL SL+E +               +E      CE H E+ H +CE
Sbjct: 55  LCKKPFKKENIRPVWQLASLVENIERLKVDKGRQPGEVTREQQDAKLCERHREKLHYYCE 114

Query: 106 DEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRI 165
           D+G+L+C  C  + +H+ HT  L+E   Q ++EK+   ++ L++  D+    +      I
Sbjct: 115 DDGKLLCVMCRESREHRPHTAVLMEKAAQPHREKILNHLSTLRRDRDKIQGFQAKGEADI 174

Query: 166 TKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQ-TLSRLRDYEAGLGLKSN 224
               +K+Q QRQ I ++F+    FL E E+  L +L K EQ+ T  R +    G+G +  
Sbjct: 175 LAALKKLQDQRQYIVAEFEQGHQFLREREEHLLEQLAKLEQELTEGREKFKSRGVG-ELA 233

Query: 225 ELKSHILELEEKCQGSAQKLLQNVNDTLSR------------SWAVKLETSEAVSLELHT 272
            L   I ELE K Q  A +L+Q+  D L+R            +  VK +T E     L  
Sbjct: 234 RLALVISELEGKAQQPAAELMQDTRDFLNRYPRKKFWVGKPIARVVKKKTGEFSDKLLSL 293

Query: 273 MCNVSKLYFDVKKMLRSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTA 332
              + +    + + L    VSVTLDP +A   L LSED + VT     ++     ++F  
Sbjct: 294 QRGLREFQGKLLRDLEYKTVSVTLDPQSASGYLQLSEDWKCVTYTSLYKSAYLHPQQFDC 353

Query: 333 FPCVLGCEGFTSGRRYFEVDV---------------------------GEGTGWD----- 360
            P VLG +GFT G+ Y+EV+V                           G G G+D     
Sbjct: 354 EPGVLGSKGFTWGKVYWEVEVEREGWSEDEEEGDEEEEGEEEEEEEEAGYGDGYDDWETD 413

Query: 361 -------------------------LGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVA 395
                                    +GV  ++V+R   +   P+ G W LRL    G  A
Sbjct: 414 EDEESLGDEEEEEEEEEEEVLESCMVGVARDSVKRKGDLSLRPEDGVWALRL-SSSGIWA 472

Query: 396 LTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPY 449
            TSP   L    +P  VGI LDYE G V+F N  +   I+TF  A+F+  L P+
Sbjct: 473 NTSPEAELFPALRPRRVGIALDYEGGTVTFTNAESQELIYTF-TATFTRRLVPF 525


>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
          Length = 630

 Score =  205 bits (521), Expect = 8e-53
 Identities = 140/443 (31%), Positives = 215/443 (48%), Gaps = 51/443 (11%)

Query: 57  FCCPQCRAPFHMDSLRPNKQLGSLIEALKE-----------TDQEMSCEEHGEQFHLFCE 105
           F CPQCR  F   S RPN QL ++++ +++           TDQ + C +H E   LFCE
Sbjct: 181 FTCPQCRKSFPRRSFRPNLQLANMVQVIRQMHPTPGRGSRVTDQGI-CPKHQEALKLFCE 239

Query: 106 DEGQLICWRCERAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRI 165
            + + IC  C  +  HK H+   +E+V Q YK KLQ  V  L++  +   + K     R+
Sbjct: 240 VDEEAICVVCRESRSHKQHSVVPLEEVVQEYKAKLQGHVEPLRKHLEAVQKMKAKEERRV 299

Query: 166 TKWKEKVQIQRQKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNE 225
           T+ K +++ +   + S+F  L  FL EE+     RL +  +  L R     + L  ++ +
Sbjct: 300 TELKSQMKSELAAVASEFGRLTRFLAEEQAGLERRLREMHEAQLGRAGAAASRLAEQAAQ 359

Query: 226 LKSHILELEEKCQGSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYF---- 281
           L   + E +E+ Q    +LLQ++ +T +R   V+L+  E  S +    C      F    
Sbjct: 360 LSRLLAEAQERSQQGGLRLLQDIKETFNRCEEVQLQPPEVWSPD---PCQPHSHDFLTDA 416

Query: 282 DVKKMLR----SHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVL 337
            V+KM R    + +V +TLDPDTAH  L+LS DRR V     ++      +RF+A  CVL
Sbjct: 417 IVRKMSRMFCQAARVDLTLDPDTAHPALMLSPDRRGVRLAERRQEVADHPKRFSADCCVL 476

Query: 338 GCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQR-----------GTG------------- 373
           G +GF SGR Y+EV+VG   GW +G   E+              G+G             
Sbjct: 477 GAQGFRSGRHYWEVEVGGRRGWAVGAARESTHHKEKVGPGGSSVGSGDASSSRHHHRRRR 536

Query: 374 --MKQEP--QSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGN 429
             + Q+P  Q   W +    K+     ++  T L   E+P   G++LDYEAG + FYN  
Sbjct: 537 LHLPQQPLLQREVWCVGTNGKRYQAQSSTEQTLLSPSEKPRRFGVYLDYEAGRLGFYNAE 596

Query: 430 TGCHIFTFPKASFSDTLRPYFQV 452
           T  H+ TF  A   + + P+F+V
Sbjct: 597 TLAHVHTFSAAFLGERVFPFFRV 619



 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 18/35 (51%), Positives = 26/35 (74%)

Query: 10 MMEEATCSICLSLMTNPVSINCGHSYCHLCITDFF 44
          + EEA C+ICL   T+PVSI CGH++C +C+T  +
Sbjct: 14 LQEEAVCAICLDYFTDPVSIGCGHNFCRVCVTQLW 48


>gi|4557743 Mediterranean fever protein [Homo sapiens]
          Length = 781

 Score =  197 bits (500), Expect = 2e-50
 Identities = 131/417 (31%), Positives = 208/417 (49%), Gaps = 37/417 (8%)

Query: 59  CPQCRAPFHMDSLRPNKQLGSLIEALKETDQEM-SCEEHGEQFHL-FCEDEGQLICWRCE 116
           CP+C+     DS    K  GSL      + Q +  C+ H +Q  L FCED  + IC  C 
Sbjct: 352 CPRCQ-----DS-HERKSPGSL------SPQPLPQCKRHLKQVQLLFCEDHDEPICLICS 399

Query: 117 RAPQHKGHTTALVEDVCQGYKEKLQKAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQR 176
            + +H+GH    +E+V   +K+K+QK +  LK+L     EQ+     +   + ++ +  +
Sbjct: 400 LSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALK 459

Query: 177 QKIRSDFKNLQCFLHEEEKSYLWRLEKEEQQTLSRLRDYEAGLGLKSNELKSHILELEEK 236
           Q+++   + +  FL ++E  ++  LE   Q      + Y+  +      L + I ELE K
Sbjct: 460 QRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAK 519

Query: 237 CQGSAQKLLQNVNDTLSRSWAV----KLETSEAVSLELHTMCNVSKLY------------ 280
              S  +LLQ++ D L R+  V    K  T + +  ++  +   S+              
Sbjct: 520 ECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLR 579

Query: 281 -----FDVKKML--RSHQVSVTLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAF 333
                F+V +++  ++H V+V LD +TA+  LI S+D + V  G   E      +RF + 
Sbjct: 580 SEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSC 639

Query: 334 PCVLGCEGFTSGRRYFEVDVGEGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGY 393
             VLG   F SGRRY+EV+VG+ T W LG C  ++ R   M   P++G+W + + K+  Y
Sbjct: 640 IIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEY 699

Query: 394 VALTSPPTSLHLHEQPLLVGIFLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450
            A + PPT L + E P  VGIF+DY  G +SFYN     HI+TF   SFS  L+P F
Sbjct: 700 QASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIF 756


>gi|88999601 tripartite motif-containing 69 isoform a [Homo sapiens]
          Length = 500

 Score =  193 bits (491), Expect = 2e-49
 Identities = 144/456 (31%), Positives = 222/456 (48%), Gaps = 31/456 (6%)

Query: 13  EATCSICLSLMTNPVSINCGHSYCHLCITDFFKNPSQKQLRQETFCCPQCRAPFHMDSLR 72
           E  C +C     +P+ ++CGH++C  CI DF++  ++     ETFC P+C+     ++  
Sbjct: 38  ELHCPLCNDWFRDPLMLSCGHNFCEACIQDFWRLQAK-----ETFC-PECKMLCQYNNCT 91

Query: 73  PNKQLGSLIEALKETDQ---EMSCEEHGEQFHLFCEDEGQLICWRCERAPQHKGHTTALV 129
            N  L  L+E +K+         C EHGE   LF + +G+LIC++C+ A    G +   +
Sbjct: 92  FNPVLDKLVEKIKKLPLLKGHPQCPEHGENLKLFSKPDGKLICFQCKDARLSVGQSKEFL 151

Query: 130 E--DVCQGYKEKLQ----KAVTKLKQLEDRCTEQKLSTAMRITKWKEKVQIQRQKIRSDF 183
           +  D    + E+L     +  T LK+L+     QK + A      KE     +Q +  +F
Sbjct: 152 QISDAVHFFTEELAIQQGQLETTLKELQTLRNMQKEAIAAH----KENKLHLQQHVSMEF 207

Query: 184 KNLQCFLHEEEKSYLWRLEKE-----EQQTLSRLRDYEAGLGLKSNELKSHILELEEKCQ 238
             L  FLH +EK  L  L +E     E+  L+  +  E  L L  + L S   + E++  
Sbjct: 208 LKLHQFLHSKEKDILTELREEGKALNEEMELNLSQLQEQCL-LAKDMLVSIQAKTEQQNS 266

Query: 239 GSAQKLLQNVNDTLSRSWAVKLETSEAVSLELHTMCNVSKLYFDVKKMLRSHQVS----V 294
               K +  +  +L +   V L T E +S +L+       + + V + ++         +
Sbjct: 267 FDFLKDITTLLHSLEQGMKV-LATRELISRKLNLGQYKGPIQYMVWREMQDTLCPGLSPL 325

Query: 295 TLDPDTAHHELILSEDRRQVTRGYTQENQDTSSRRFTAFPCVLGCEGFTSGRRYFEVDVG 354
           TLDP TAH  L+LS+ +  V  G  ++       RF +   VLG  GFTSG+ Y+EV+V 
Sbjct: 326 TLDPKTAHPNLVLSKSQTSVWHGDIKKIMPDDPERFDSSVAVLGSRGFTSGKWYWEVEVA 385

Query: 355 EGTGWDLGVCMENVQRGTGMKQEPQSGFWTLRLCKKKGYVALTSPPTSLHLHEQPLLVGI 414
           + T W +GV  E++ R       P+ GFW LRL  +    AL  P  SL L      VGI
Sbjct: 386 KKTKWTVGVVRESIIRKGSCPLTPEQGFWLLRLRNQTDLKALDLPSFSLTLTNNLDKVGI 445

Query: 415 FLDYEAGVVSFYNGNTGCHIFTFPKASFSDTLRPYF 450
           +LDYE G +SFYN  T  HI+TF   +F + L PYF
Sbjct: 446 YLDYEGGQLSFYNAKTMTHIYTFSN-TFMEKLYPYF 480


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.133    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,356,620
Number of Sequences: 37866
Number of extensions: 917948
Number of successful extensions: 4384
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 229
Number of HSP's successfully gapped in prelim test: 298
Number of HSP's that attempted gapping in prelim test: 3276
Number of HSP's gapped (non-prelim): 899
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.