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Search of human proteins with 5453593
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5453593 adenylyl cyclase-associated protein 2 [Homo sapiens]
(477 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5453593 adenylyl cyclase-associated protein 2 [Homo sapiens] 959 0.0
gi|157649073 adenylyl cyclase-associated protein [Homo sapiens] 597 e-171
gi|5453595 adenylyl cyclase-associated protein [Homo sapiens] 597 e-171
gi|47132519 Ras association and pleckstrin homology domains 1 is... 45 1e-04
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap... 45 2e-04
gi|30425428 deltex homolog 3 [Homo sapiens] 44 3e-04
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens] 42 0.001
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 42 0.001
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 42 0.001
gi|126090663 zinc finger homeodomain 4 [Homo sapiens] 42 0.001
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 41 0.003
gi|148229134 ring finger and KH domain containing 2 [Homo sapiens] 41 0.003
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 40 0.004
gi|112363080 microtubule associated serine/threonine kinase 2 [H... 40 0.004
gi|158534059 formin binding protein 4 [Homo sapiens] 40 0.004
gi|40807465 zinc finger protein 341 [Homo sapiens] 40 0.004
gi|11386183 WAS protein family, member 2 [Homo sapiens] 40 0.005
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 40 0.005
gi|150170670 piccolo isoform 2 [Homo sapiens] 40 0.006
gi|150378539 piccolo isoform 1 [Homo sapiens] 40 0.006
gi|58331242 formin homology 2 domain containing 3 [Homo sapiens] 39 0.008
gi|194294554 SET binding protein 1 isoform a [Homo sapiens] 39 0.008
gi|13273315 homeobox B4 [Homo sapiens] 39 0.008
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens] 39 0.008
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 39 0.008
gi|33286436 gametogenetin [Homo sapiens] 39 0.008
gi|157168329 formin 1 [Homo sapiens] 39 0.010
gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein ... 39 0.010
gi|6382071 diaphanous 2 isoform 12C [Homo sapiens] 39 0.010
gi|5803003 diaphanous 2 isoform 156 [Homo sapiens] 39 0.010
>gi|5453593 adenylyl cyclase-associated protein 2 [Homo sapiens]
Length = 477
Score = 959 bits (2480), Expect = 0.0
Identities = 477/477 (100%), Positives = 477/477 (100%)
Query: 1 MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEF 60
MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEF
Sbjct: 1 MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEF 60
Query: 61 LKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTF 120
LKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTF
Sbjct: 61 LKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTF 120
Query: 121 RERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLR 180
RERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLR
Sbjct: 121 RERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLR 180
Query: 181 HVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPP 240
HVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPP
Sbjct: 181 HVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPP 240
Query: 241 PGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQ 300
PGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQ
Sbjct: 241 PGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQ 300
Query: 301 SPTKSHTPSPTSPKSYPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCE 360
SPTKSHTPSPTSPKSYPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCE
Sbjct: 301 SPTKSHTPSPTSPKSYPSQKHAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCE 360
Query: 361 KSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCH 420
KSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCH
Sbjct: 361 KSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTEGCH 420
Query: 421 IYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPIPEQFKTAWDGSKLITEPAEIMA 477
IYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPIPEQFKTAWDGSKLITEPAEIMA
Sbjct: 421 IYLSEDALDCEIVSAKSSEMNILIPQDGDYREFPIPEQFKTAWDGSKLITEPAEIMA 477
>gi|157649073 adenylyl cyclase-associated protein [Homo sapiens]
Length = 475
Score = 597 bits (1540), Expect = e-171
Identities = 307/479 (64%), Positives = 374/479 (78%), Gaps = 10/479 (2%)
Query: 1 MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEF 60
MA+MQ LVERLERAV RLE++S S G + AG AP V+AFD L+ VAE+
Sbjct: 1 MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSK--AGAAPYVQAFDSLLAGPVAEY 58
Query: 61 LKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTF 120
LK S+ + GDV+ HAEMVH+ + +RA L+ ASQ QQP EN ++ LL PISE+I+E+ TF
Sbjct: 59 LKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITF 118
Query: 121 RERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLR 180
RE+NRGS +FNHLSAVSESI ALGW+A++PKPGPYVKEMNDAA FYTNRVLK+YK D +
Sbjct: 119 REKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKK 178
Query: 181 HVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPP 240
HVDWVK+YL+IW+ELQAYIKE HTTGL WSKTGPVA +S L SGP PPP PP
Sbjct: 179 HVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSG---LPSGPSAGSGPPP-PP 234
Query: 241 PGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQ 300
PGPPP + + S SRSALFAQ+NQGE+IT L+HV+DD KT+KNP+L+AQ G +
Sbjct: 235 PGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVR 294
Query: 301 S-PTKSHTPSP-TSPKSYPSQKHAP-VLELEGKKWRVEYQEDRNDLVISETELKQVAYIF 357
S P P P TSP + K P VLELEGKKWRVE QE+ ++LVI +TELKQVAYI+
Sbjct: 295 SGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIY 354
Query: 358 KCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTE 417
KC +T+QIKGK+NSI +DNCKKLGLVFD+VVGIVE+INS+D+++QVMG+VPTISINKT+
Sbjct: 355 KCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTD 414
Query: 418 GCHIYLSEDALDCEIVSAKSSEMNILIP-QDGDYREFPIPEQFKTAWDGSKLITEPAEI 475
GCH YLS+++LDCEIVSAKSSEMN+LIP + GD+ EFP+PEQFKT W+G KL+T EI
Sbjct: 415 GCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEI 473
>gi|5453595 adenylyl cyclase-associated protein [Homo sapiens]
Length = 475
Score = 597 bits (1540), Expect = e-171
Identities = 307/479 (64%), Positives = 374/479 (78%), Gaps = 10/479 (2%)
Query: 1 MANMQGLVERLERAVSRLESLSAESHRPPGNCGEVNGVIAGVAPSVEAFDKLMDSMVAEF 60
MA+MQ LVERLERAV RLE++S S G + AG AP V+AFD L+ VAE+
Sbjct: 1 MADMQNLVERLERAVGRLEAVSHTSDMHRGYADSPSK--AGAAPYVQAFDSLLAGPVAEY 58
Query: 61 LKNSRILAGDVETHAEMVHSAFQAQRAFLLMASQYQQPHENDVAALLKPISEKIQEIQTF 120
LK S+ + GDV+ HAEMVH+ + +RA L+ ASQ QQP EN ++ LL PISE+I+E+ TF
Sbjct: 59 LKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPISEQIKEVITF 118
Query: 121 RERNRGSNMFNHLSAVSESIPALGWIAVSPKPGPYVKEMNDAATFYTNRVLKDYKHSDLR 180
RE+NRGS +FNHLSAVSESI ALGW+A++PKPGPYVKEMNDAA FYTNRVLK+YK D +
Sbjct: 119 REKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKDVDKK 178
Query: 181 HVDWVKSYLNIWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPP 240
HVDWVK+YL+IW+ELQAYIKE HTTGL WSKTGPVA +S L SGP PPP PP
Sbjct: 179 HVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSG---LPSGPSAGSGPPP-PP 234
Query: 241 PGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQ 300
PGPPP + + S SRSALFAQ+NQGE+IT L+HV+DD KT+KNP+L+AQ G +
Sbjct: 235 PGPPPPPVSTSSGSDESASRSALFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVR 294
Query: 301 S-PTKSHTPSP-TSPKSYPSQKHAP-VLELEGKKWRVEYQEDRNDLVISETELKQVAYIF 357
S P P P TSP + K P VLELEGKKWRVE QE+ ++LVI +TELKQVAYI+
Sbjct: 295 SGPKPFSAPKPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIY 354
Query: 358 KCEKSTIQIKGKVNSIIIDNCKKLGLVFDNVVGIVEVINSQDIQIQVMGRVPTISINKTE 417
KC +T+QIKGK+NSI +DNCKKLGLVFD+VVGIVE+INS+D+++QVMG+VPTISINKT+
Sbjct: 355 KCVNTTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTD 414
Query: 418 GCHIYLSEDALDCEIVSAKSSEMNILIP-QDGDYREFPIPEQFKTAWDGSKLITEPAEI 475
GCH YLS+++LDCEIVSAKSSEMN+LIP + GD+ EFP+PEQFKT W+G KL+T EI
Sbjct: 415 GCHAYLSKNSLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEI 473
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 45.1 bits (105), Expect = 1e-04
Identities = 28/104 (26%), Positives = 40/104 (38%)
Query: 214 PVASTVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAI 273
P V+ ++ P LPPPPPP PPP PPP +S+PS + + I
Sbjct: 611 PQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTI 670
Query: 274 TKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYP 317
T+ +K P+ Q+ P P+ P P
Sbjct: 671 TRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP 714
Score = 33.5 bits (75), Expect = 0.44
Identities = 29/97 (29%), Positives = 40/97 (41%), Gaps = 15/97 (15%)
Query: 232 PPPPP---PLPPPGPPPLFE-------NEGKK--EESSP--SRSALFAQLNQGEAITKGL 277
PPPPP P PPP PPP + GKK + SSP + Q N + G
Sbjct: 928 PPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGA 987
Query: 278 RHVTDDQKTYKN-PSLRAQGGQTQSPTKSHTPSPTSP 313
H + + + S ++ SP+K P P +P
Sbjct: 988 EHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAP 1024
Score = 32.0 bits (71), Expect = 1.3
Identities = 11/16 (68%), Positives = 12/16 (75%)
Query: 229 PGLPPPPPPLPPPGPP 244
P PPPPPP+P P PP
Sbjct: 760 PPTPPPPPPIPAPLPP 775
Score = 30.8 bits (68), Expect = 2.8
Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 1/58 (1%)
Query: 203 HTTGLTWSKTGPVASTVSAFSVLSSGP-GLPPPPPPLPPPGPPPLFENEGKKEESSPS 259
H+ L T PV + S + P G+ PPPPP PPP P + K +PS
Sbjct: 679 HSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPS 736
Score = 30.0 bits (66), Expect = 4.8
Identities = 31/111 (27%), Positives = 46/111 (41%), Gaps = 14/111 (12%)
Query: 212 TGPVASTVSAFSVLSSGPGLPPPPP----PLPPPGPPPLFENEGKKEESSPSRSALFAQL 267
+G +V F S PPPPP PLPP P +F +SP + + Q
Sbjct: 1054 SGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSG-----NTSPKVAVVNPQP 1108
Query: 268 NQGEAITKGLRHVTDDQKTYKNPSLR-AQGGQTQSPTKSHT--PSPTSPKS 315
Q ++ ++ + +N S R Q ++ PT + PTSPKS
Sbjct: 1109 QQWSKMS--VKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKS 1157
>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
sapiens]
Length = 505
Score = 44.7 bits (104), Expect = 2e-04
Identities = 35/103 (33%), Positives = 51/103 (49%), Gaps = 14/103 (13%)
Query: 223 SVLSSGPGLPPPPPPLPP---PGPPPLFENEGKKE--ESSPSRSALFAQLNQGEAITK-- 275
SVL GP PPPPPP PP P PPP ++G + ++ +++AL Q+ +G + K
Sbjct: 364 SVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQIREGAQLKKVE 423
Query: 276 -GLRHVTDDQKTYKNPSLRAQGGQTQSPTKSH-----TPSPTS 312
R V+ + +R QG Q +S TP+PTS
Sbjct: 424 QNSRPVSCSGRDALLDQIR-QGIQLKSVADGQESTPPTPAPTS 465
Score = 32.3 bits (72), Expect = 0.97
Identities = 23/78 (29%), Positives = 38/78 (48%), Gaps = 10/78 (12%)
Query: 178 DLRHVD-WVKSYLNIWSELQAYIKEHHTTGLTWS---KTGPVASTVSAFSVLSSGP---- 229
DL ++D +K+ ++ +A +K+ T+ + + KTG V + + + P
Sbjct: 224 DLNNLDPELKNLFDMCGISEAQLKDRETSKVIYDFIEKTGGVEAVKNELRRQAPPPPPPS 283
Query: 230 --GLPPPPPPLPPPGPPP 245
G PPPPPP GPPP
Sbjct: 284 RGGPPPPPPPPHNSGPPP 301
Score = 29.3 bits (64), Expect = 8.2
Identities = 12/17 (70%), Positives = 12/17 (70%), Gaps = 3/17 (17%)
Query: 232 PPPPPPLP---PPGPPP 245
PPPPP LP P GPPP
Sbjct: 344 PPPPPALPSSAPSGPPP 360
>gi|30425428 deltex homolog 3 [Homo sapiens]
Length = 347
Score = 43.9 bits (102), Expect = 3e-04
Identities = 18/29 (62%), Positives = 21/29 (72%)
Query: 230 GLPPPPPPLPPPGPPPLFENEGKKEESSP 258
GLPPPPPPLPPP PP L E ++E + P
Sbjct: 137 GLPPPPPPLPPPLPPRLREEAEEQESTCP 165
>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
Length = 374
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 12/73 (16%)
Query: 209 WSKTGPVASTVSAFSVLSSGPGLPPPPPP------------LPPPGPPPLFENEGKKEES 256
W+ G A+TV A + G PPPPP LPPP PPP ++E
Sbjct: 63 WTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEEAP 122
Query: 257 SPSRSALFAQLNQ 269
+P ++L A L Q
Sbjct: 123 APMGASLIADLEQ 135
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 42.4 bits (98), Expect = 0.001
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 12/73 (16%)
Query: 209 WSKTGPVASTVSAFSVLSSGPGLPPPPPP------------LPPPGPPPLFENEGKKEES 256
W+ G A+TV A + G PPPPP LPPP PPP ++E
Sbjct: 63 WTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEEAP 122
Query: 257 SPSRSALFAQLNQ 269
+P ++L A L Q
Sbjct: 123 APMGASLIADLEQ 135
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/109 (33%), Positives = 42/109 (38%), Gaps = 21/109 (19%)
Query: 217 STVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKG 276
ST SA + S P LPPPPPP P PP L EG E+SS A + G A T G
Sbjct: 292 STPSAGTPQSQPPPLPPPPPPAPGSAPPAL-PPEGPPEDSSQD----LAPNSVGAASTGG 346
Query: 277 LRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVL 325
G +PT + +P P PS P L
Sbjct: 347 ----------------GTGGTHPNTPTATTANNPLPPGGDPSSAPGPAL 379
>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
Length = 3571
Score = 42.0 bits (97), Expect = 0.001
Identities = 18/36 (50%), Positives = 21/36 (58%)
Query: 210 SKTGPVASTVSAFSVLSSGPGLPPPPPPLPPPGPPP 245
S GPV + + L + P PPPPPP PPP PPP
Sbjct: 1975 SSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPP 2010
Score = 38.5 bits (88), Expect = 0.014
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 214 PVASTVSAFSVLSSGPGLP---PPPPPLPPPGPPPLFENEGKKEESSPSRS 261
P ++T S LSS P P PPPP PPP PPP G++ E S
Sbjct: 3094 PTSATSSPALSLSSAPTKPLLQTPPPPPPPPPPPPSSSLSGQQTEQQNKES 3144
Score = 35.8 bits (81), Expect = 0.088
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PPP
Sbjct: 1999 PPPPPPPPPPPPPPPPP 2015
Score = 35.8 bits (81), Expect = 0.088
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PPP
Sbjct: 2000 PPPPPPPPPPPPPPPPP 2016
Score = 33.5 bits (75), Expect = 0.44
Identities = 12/17 (70%), Positives = 12/17 (70%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PP
Sbjct: 2004 PPPPPPPPPPPPPSAPP 2020
Score = 32.3 bits (72), Expect = 0.97
Identities = 12/17 (70%), Positives = 12/17 (70%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPPLPP P P
Sbjct: 1958 PPPPPPPPPLPPAPPQP 1974
Score = 32.0 bits (71), Expect = 1.3
Identities = 13/23 (56%), Positives = 15/23 (65%), Gaps = 1/23 (4%)
Query: 222 FSVLSSGPGLPPPPPPLPPPGPP 244
+ + S P PPPPPP PPP PP
Sbjct: 1948 YPISPSSPETPPPPPP-PPPLPP 1969
Score = 30.4 bits (67), Expect = 3.7
Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 13/69 (18%)
Query: 229 PGLPPPPPPLPPP--GPP----------PLFENEGKKEESSPSRSALFA-QLNQGEAITK 275
P PPPPPP PPP PP PLF + + P+ A QL Q +A++
Sbjct: 2003 PPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQLALQLPQMDALSA 2062
Query: 276 GLRHVTDDQ 284
L + Q
Sbjct: 2063 DLTQLCQQQ 2071
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 40.8 bits (94), Expect = 0.003
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 13/60 (21%)
Query: 229 PGLPPPPPPLPPPGP------------PPLFENEGKKEESSP-SRSALFAQLNQGEAITK 275
P PPPPPPLPPP P PP+ + + P RSAL A + QG + K
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
Score = 37.7 bits (86), Expect = 0.023
Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 14/92 (15%)
Query: 229 PGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYK 288
P +P PPPP PPP PPPL SSP ++ L ++ +TKG V
Sbjct: 169 PNVPAPPPPTPPPPPPPL---PPPLPSSSPIKTPL---VSPPGPLTKGNLPVVAPPVPCA 222
Query: 289 NPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQK 320
P P TP P P S S K
Sbjct: 223 PP--------PPPPPPPPTPPPLPPASVLSDK 246
Score = 30.0 bits (66), Expect = 4.8
Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 5/34 (14%)
Query: 229 PGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSA 262
P +PPP P LPP G P L K E +SP++ A
Sbjct: 258 PPIPPPLPLLPPCGYPGL-----KAEPASPAQDA 286
>gi|148229134 ring finger and KH domain containing 2 [Homo sapiens]
Length = 659
Score = 40.8 bits (94), Expect = 0.003
Identities = 42/138 (30%), Positives = 54/138 (39%), Gaps = 16/138 (11%)
Query: 220 SAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRH 279
SA L++ P P PPP PPP PPPL G E L + GL
Sbjct: 6 SAALALAAAPAPLPQPPPPPPPPPPPLPPPSGGPELEGD------GLLLRERLAALGL-- 57
Query: 280 VTDDQKTYK--NPSLRAQGGQTQSPTK---SHTPSPTSPKSYPSQKHAPVLELEGKKWRV 334
DD + P+LRA Q + +P +P P A LELE +
Sbjct: 58 --DDPSPAEPGAPALRAPAAAAQGQARRAAELSPEERAPPGRPGAPEAAELELEEDEEEG 115
Query: 335 EYQEDRNDLVISETELKQ 352
E E DL + E EL++
Sbjct: 116 EEAELDGDL-LEEEELEE 132
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 40.4 bits (93), Expect = 0.004
Identities = 15/17 (88%), Positives = 15/17 (88%)
Query: 229 PGLPPPPPPLPPPGPPP 245
PGLP PPPPLPPP PPP
Sbjct: 242 PGLPLPPPPLPPPPPPP 258
Score = 36.6 bits (83), Expect = 0.051
Identities = 15/18 (83%), Positives = 15/18 (83%), Gaps = 1/18 (5%)
Query: 229 PGLPPPPPPLPPPGPPPL 246
P LPPPPPP PPP PPPL
Sbjct: 249 PPLPPPPPP-PPPPPPPL 265
Score = 34.3 bits (77), Expect = 0.26
Identities = 30/116 (25%), Positives = 41/116 (35%), Gaps = 33/116 (28%)
Query: 207 LTWSKTGPVASTVSAFSVLSSGPGLPPPPP---------PLPPPGPPPLFENEGKKEESS 257
+T + T +T + P LPPPPP P PPP PPP S
Sbjct: 751 VTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPP-----------S 799
Query: 258 PSRSALFAQLNQGEAITKGLRHVTDDQK-TYKNPSLRAQGGQTQSPTKSHTPSPTS 312
P+ ++ K L V + QK Y+ PT ++P P S
Sbjct: 800 PA------------SLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPS 843
Score = 33.9 bits (76), Expect = 0.33
Identities = 14/21 (66%), Positives = 14/21 (66%)
Query: 225 LSSGPGLPPPPPPLPPPGPPP 245
L G LPPPP P PPP PPP
Sbjct: 240 LPPGLPLPPPPLPPPPPPPPP 260
Score = 31.2 bits (69), Expect = 2.2
Identities = 11/14 (78%), Positives = 11/14 (78%)
Query: 232 PPPPPPLPPPGPPP 245
PPPPPP PPP P P
Sbjct: 253 PPPPPPPPPPPPLP 266
Score = 29.6 bits (65), Expect = 6.3
Identities = 11/15 (73%), Positives = 11/15 (73%)
Query: 229 PGLPPPPPPLPPPGP 243
P PPPPPP PPP P
Sbjct: 252 PPPPPPPPPPPPPLP 266
Score = 29.3 bits (64), Expect = 8.2
Identities = 11/15 (73%), Positives = 11/15 (73%)
Query: 232 PPPPPPLPPPGPPPL 246
PPPPPP PPP P L
Sbjct: 254 PPPPPPPPPPPLPGL 268
>gi|112363080 microtubule associated serine/threonine kinase 2 [Homo
sapiens]
Length = 1798
Score = 40.4 bits (93), Expect = 0.004
Identities = 31/108 (28%), Positives = 45/108 (41%), Gaps = 11/108 (10%)
Query: 227 SGPGLPPPPPPLPPPGP-------PPLFENEG--KKEESSPSRSALFAQLNQGEAITKGL 277
SGPG P L P P P + G + SSPS S + G L
Sbjct: 1260 SGPGSPTHSHSLSPRSPTQGYRVTPDAVHSVGGNSSQSSSPSSSVPSSPAGSGHTRPSSL 1319
Query: 278 RHVTDD-QKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPV 324
+ Q+ Y++P ++ G SP +HTPSP P + P + +P+
Sbjct: 1320 HGLAPKLQRQYRSPRRKSAGSIPLSPL-AHTPSPPPPTASPQRSPSPL 1366
Score = 30.4 bits (67), Expect = 3.7
Identities = 20/65 (30%), Positives = 32/65 (49%), Gaps = 5/65 (7%)
Query: 249 NEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTP 308
+ GK + S RS+LF ++ + ++ R ++ N SL + SPT SH+
Sbjct: 1217 SRGKDGQESRKRSSLFRKITKQASLLHTSRSLSS-----LNRSLSSGESGPGSPTHSHSL 1271
Query: 309 SPTSP 313
SP SP
Sbjct: 1272 SPRSP 1276
>gi|158534059 formin binding protein 4 [Homo sapiens]
Length = 1017
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/94 (25%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 206 GLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLPPPG----PPPLFENEGKKEESSPSRS 261
G+T PV + + + P PPPPPP PPP PPP +G+K+++ S++
Sbjct: 882 GVTAPSLQPVQARGAVPTATIIEPPPPPPPPPPPPPPAPKMPPPEKTKKGRKDKAKKSKT 941
Query: 262 ALFAQLNQGEAITKGLRHVTDDQKTYKNPSLRAQ 295
+ + + + ++I + L + + ++ AQ
Sbjct: 942 KMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQ 975
Score = 34.3 bits (77), Expect = 0.26
Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 12/42 (28%)
Query: 229 PGLPPPPPPLPPPGPPP------------LFENEGKKEESSP 258
P PPPPP PPP PPP E+EG +E +P
Sbjct: 712 PPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAP 753
>gi|40807465 zinc finger protein 341 [Homo sapiens]
Length = 847
Score = 40.4 bits (93), Expect = 0.004
Identities = 19/34 (55%), Positives = 23/34 (67%), Gaps = 3/34 (8%)
Query: 214 PVASTVSAFSV---LSSGPGLPPPPPPLPPPGPP 244
PV S+++ SV L+ P PPPPPPLPPP PP
Sbjct: 161 PVQSSLNMHSVPSYLTQPPPPPPPPPPLPPPPPP 194
Score = 36.2 bits (82), Expect = 0.067
Identities = 13/16 (81%), Positives = 13/16 (81%)
Query: 229 PGLPPPPPPLPPPGPP 244
P LPPPPPP PPP PP
Sbjct: 186 PPLPPPPPPQPPPPPP 201
>gi|11386183 WAS protein family, member 2 [Homo sapiens]
Length = 498
Score = 40.0 bits (92), Expect = 0.005
Identities = 14/16 (87%), Positives = 14/16 (87%)
Query: 230 GLPPPPPPLPPPGPPP 245
G PPPPPP PPPGPPP
Sbjct: 389 GAPPPPPPPPPPGPPP 404
Score = 34.3 bits (77), Expect = 0.26
Identities = 16/33 (48%), Positives = 18/33 (54%), Gaps = 3/33 (9%)
Query: 229 PGLPPPPPP---LPPPGPPPLFENEGKKEESSP 258
P PPPPPP +PPP PP F + G SP
Sbjct: 320 PAPPPPPPPMIGIPPPPPPVGFGSPGTPPPPSP 352
Score = 33.1 bits (74), Expect = 0.57
Identities = 13/27 (48%), Positives = 16/27 (59%)
Query: 226 SSGPGLPPPPPPLPPPGPPPLFENEGK 252
+ G PPPPPP P P PPP +G+
Sbjct: 387 TGGAPPPPPPPPPPGPPPPPFTGADGQ 413
Score = 31.6 bits (70), Expect = 1.7
Identities = 14/24 (58%), Positives = 15/24 (62%), Gaps = 2/24 (8%)
Query: 225 LSSGPGLPP--PPPPLPPPGPPPL 246
L S PG P PPP PPP PPP+
Sbjct: 306 LGSPPGPKPGFAPPPAPPPPPPPM 329
Score = 29.3 bits (64), Expect = 8.2
Identities = 13/20 (65%), Positives = 13/20 (65%), Gaps = 1/20 (5%)
Query: 229 PGLPPPPPPL-PPPGPPPLF 247
P PPP PPL PPGP P F
Sbjct: 297 PSHPPPAPPLGSPPGPKPGF 316
Score = 29.3 bits (64), Expect = 8.2
Identities = 13/27 (48%), Positives = 13/27 (48%), Gaps = 10/27 (37%)
Query: 229 PGLPPPPPP----------LPPPGPPP 245
PG PPPP P PPP PPP
Sbjct: 344 PGTPPPPSPPSFPPHPDFAAPPPPPPP 370
>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
Length = 796
Score = 40.0 bits (92), Expect = 0.005
Identities = 30/103 (29%), Positives = 41/103 (39%), Gaps = 12/103 (11%)
Query: 218 TVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGL 277
T+SA + G PPPP PP GP N ES+P G + L
Sbjct: 580 TMSAGGFAAPGHAAGGPPPPPPPLGP---HSNRTTPPESAP---------QNGPSPMAAL 627
Query: 278 RHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQK 320
V D T +P + T + + ++ SP SP S P Q+
Sbjct: 628 MSVADTLGTAHSPKDGSSVHSTTASARRNSSSPVSPASVPGQR 670
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 39.7 bits (91), Expect = 0.006
Identities = 32/91 (35%), Positives = 38/91 (41%), Gaps = 6/91 (6%)
Query: 229 PGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYK 288
P PPPPPP PPP PPPL K P + A + T VT + T
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA--SPVTTATPLFDAVTTLETT-- 2465
Query: 289 NPSLRAQG-GQTQSPTKSHTPSPTSPKSYPS 318
LR+ G T+ T + P P P S PS
Sbjct: 2466 -AVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495
Score = 37.7 bits (86), Expect = 0.023
Identities = 14/26 (53%), Positives = 17/26 (65%)
Query: 220 SAFSVLSSGPGLPPPPPPLPPPGPPP 245
S+ + + P PPPPPP PPP PPP
Sbjct: 2397 SSLDISAQPPPPPPPPPPPPPPPPPP 2422
Score = 35.8 bits (81), Expect = 0.088
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PPP
Sbjct: 2407 PPPPPPPPPPPPPPPPP 2423
Score = 35.8 bits (81), Expect = 0.088
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PPP
Sbjct: 2408 PPPPPPPPPPPPPPPPP 2424
Score = 35.8 bits (81), Expect = 0.088
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PPP
Sbjct: 2409 PPPPPPPPPPPPPPPPP 2425
Score = 33.5 bits (75), Expect = 0.44
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 12/56 (21%)
Query: 202 HHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPP------------PPPLPPPGPPP 245
+ T+G T+ + P + S +SS P P P PPP PPP PPP
Sbjct: 2360 YFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP 2415
Score = 31.2 bits (69), Expect = 2.2
Identities = 30/118 (25%), Positives = 38/118 (32%), Gaps = 6/118 (5%)
Query: 212 TGPVASTVSAFSVLSSGPGLPPPPP-PLPPPGPPPLFENEGKKEESSPSRSALFAQLNQG 270
T P+A PG PP PL P PP K P AL G
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 271 EAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPT-----SPKSYPSQKHAP 323
+ + + P AQ QSP K+ P+ T P P+Q+ P
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP 456
Score = 31.2 bits (69), Expect = 2.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 277 LRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAP 323
++H++ +KTYK SL G QT++ + + +P S S P K P
Sbjct: 3550 IKHISAPEKTYKGGSL---GCQTEADSDTQSPQYLSATSPPKDKKRP 3593
Score = 29.3 bits (64), Expect = 8.2
Identities = 30/116 (25%), Positives = 40/116 (34%), Gaps = 12/116 (10%)
Query: 216 ASTVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITK 275
A V SV S P PP P PG PP + +K + P++ Q +TK
Sbjct: 286 ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA-----QPSGLTK 340
Query: 276 GLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKK 331
L K P G T+ P + P P + + P E G K
Sbjct: 341 PLAQQPGTVKPPVQPP-----GTTKPP--AQPLGPAKPPAQQTGSEKPSSEQPGPK 389
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 39.7 bits (91), Expect = 0.006
Identities = 32/91 (35%), Positives = 38/91 (41%), Gaps = 6/91 (6%)
Query: 229 PGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYK 288
P PPPPPP PPP PPPL K P + A + T VT + T
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA--SPVTTATPLFDAVTTLETT-- 2465
Query: 289 NPSLRAQG-GQTQSPTKSHTPSPTSPKSYPS 318
LR+ G T+ T + P P P S PS
Sbjct: 2466 -AVLRSNGLPVTRICTTAPPPVPPKPSSIPS 2495
Score = 37.7 bits (86), Expect = 0.023
Identities = 14/26 (53%), Positives = 17/26 (65%)
Query: 220 SAFSVLSSGPGLPPPPPPLPPPGPPP 245
S+ + + P PPPPPP PPP PPP
Sbjct: 2397 SSLDISAQPPPPPPPPPPPPPPPPPP 2422
Score = 35.8 bits (81), Expect = 0.088
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PPP
Sbjct: 2407 PPPPPPPPPPPPPPPPP 2423
Score = 35.8 bits (81), Expect = 0.088
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PPP
Sbjct: 2408 PPPPPPPPPPPPPPPPP 2424
Score = 35.8 bits (81), Expect = 0.088
Identities = 13/17 (76%), Positives = 13/17 (76%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPP PPP
Sbjct: 2409 PPPPPPPPPPPPPPPPP 2425
Score = 33.5 bits (75), Expect = 0.44
Identities = 19/56 (33%), Positives = 25/56 (44%), Gaps = 12/56 (21%)
Query: 202 HHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPP------------PPPLPPPGPPP 245
+ T+G T+ + P + S +SS P P P PPP PPP PPP
Sbjct: 2360 YFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP 2415
Score = 31.2 bits (69), Expect = 2.2
Identities = 30/118 (25%), Positives = 38/118 (32%), Gaps = 6/118 (5%)
Query: 212 TGPVASTVSAFSVLSSGPGLPPPPP-PLPPPGPPPLFENEGKKEESSPSRSALFAQLNQG 270
T P+A PG PP PL P PP K P AL G
Sbjct: 339 TKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVG 398
Query: 271 EAITKGLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPT-----SPKSYPSQKHAP 323
+ + + P AQ QSP K+ P+ T P P+Q+ P
Sbjct: 399 KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGP 456
Score = 31.2 bits (69), Expect = 2.2
Identities = 16/47 (34%), Positives = 26/47 (55%), Gaps = 3/47 (6%)
Query: 277 LRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAP 323
++H++ +KTYK SL G QT++ + + +P S S P K P
Sbjct: 3550 IKHISAPEKTYKGGSL---GCQTEADSDTQSPQYLSATSPPKDKKRP 3593
Score = 29.3 bits (64), Expect = 8.2
Identities = 30/116 (25%), Positives = 40/116 (34%), Gaps = 12/116 (10%)
Query: 216 ASTVSAFSVLSSGPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITK 275
A V SV S P PP P PG PP + +K + P++ Q +TK
Sbjct: 286 ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPA-----QPSGLTK 340
Query: 276 GLRHVTDDQKTYKNPSLRAQGGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKK 331
L K P G T+ P + P P + + P E G K
Sbjct: 341 PLAQQPGTVKPPVQPP-----GTTKPP--AQPLGPAKPPAQQTGSEKPSSEQPGPK 389
>gi|58331242 formin homology 2 domain containing 3 [Homo sapiens]
Length = 1439
Score = 39.3 bits (90), Expect = 0.008
Identities = 23/66 (34%), Positives = 31/66 (46%), Gaps = 8/66 (12%)
Query: 191 IWSELQAYIKEHHTTGLTWSKTGPVASTVSAFSV---LSSGPGLPPPPPP----LPPPGP 243
IW +L A +E + ++ G + V PG PPPPPP LPPP P
Sbjct: 804 IWDQLMANPRELRIQDMDFTDLGE-EDDIDVLDVDLGHREAPGPPPPPPPTFLGLPPPPP 862
Query: 244 PPLFEN 249
PPL ++
Sbjct: 863 PPLLDS 868
Score = 30.0 bits (66), Expect = 4.8
Identities = 15/31 (48%), Positives = 17/31 (54%), Gaps = 13/31 (41%)
Query: 230 GLPPPPPP-----LPPP--------GPPPLF 247
GLPPPPPP +PPP PPP+F
Sbjct: 856 GLPPPPPPPLLDSIPPPPVPGNLLVPPPPVF 886
>gi|194294554 SET binding protein 1 isoform a [Homo sapiens]
Length = 1596
Score = 39.3 bits (90), Expect = 0.008
Identities = 14/15 (93%), Positives = 14/15 (93%)
Query: 232 PPPPPPLPPPGPPPL 246
PPPPPPLPPP PPPL
Sbjct: 1524 PPPPPPLPPPPPPPL 1538
Score = 36.6 bits (83), Expect = 0.051
Identities = 14/23 (60%), Positives = 16/23 (69%)
Query: 232 PPPPPPLPPPGPPPLFENEGKKE 254
PPPPPPLPPP P P GK++
Sbjct: 1532 PPPPPPLPPPPPLPKTPRGGKRK 1554
Score = 30.0 bits (66), Expect = 4.8
Identities = 13/33 (39%), Positives = 18/33 (54%)
Query: 214 PVASTVSAFSVLSSGPGLPPPPPPLPPPGPPPL 246
P AS + + + + + PPLPPP PPPL
Sbjct: 1498 PAASQDTIMATIEAVIHMAREAPPLPPPPPPPL 1530
>gi|13273315 homeobox B4 [Homo sapiens]
Length = 251
Score = 39.3 bits (90), Expect = 0.008
Identities = 17/30 (56%), Positives = 19/30 (63%), Gaps = 1/30 (3%)
Query: 216 ASTVSAFSVLSSGPGLPPPPPPLPPPGPPP 245
A TV ++ PG PPPPPP PPP PPP
Sbjct: 59 ACTVQRYAACRD-PGPPPPPPPPPPPPPPP 87
Score = 33.1 bits (74), Expect = 0.57
Identities = 15/38 (39%), Positives = 18/38 (47%)
Query: 232 PPPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQ 269
P PPPP PPP PPP + + P AL + Q
Sbjct: 71 PGPPPPPPPPPPPPPPPGLSPRAPAPPPAGALLPEPGQ 108
Score = 32.0 bits (71), Expect = 1.3
Identities = 12/17 (70%), Positives = 12/17 (70%)
Query: 229 PGLPPPPPPLPPPGPPP 245
P PPPPPP PPPG P
Sbjct: 75 PPPPPPPPPPPPPGLSP 91
>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
Length = 1303
Score = 39.3 bits (90), Expect = 0.008
Identities = 18/34 (52%), Positives = 20/34 (58%), Gaps = 1/34 (2%)
Query: 213 GPVASTVSAFSVLSSGPGLPPPPPPLPPPGPPPL 246
GP A T + GP PPPPPP PPPGPP +
Sbjct: 525 GPQAPTSPNGRPMQGGPP-PPPPPPPPPPGPPQM 557
Score = 33.5 bits (75), Expect = 0.44
Identities = 13/23 (56%), Positives = 15/23 (65%), Gaps = 2/23 (8%)
Query: 225 LSSGPGLPPPPP--PLPPPGPPP 245
+ + PG PPPPP PPP PPP
Sbjct: 1 MEAAPGTPPPPPSESPPPPSPPP 23
>gi|21071077 dishevelled-associated activator of morphogenesis 1
[Homo sapiens]
Length = 1078
Score = 39.3 bits (90), Expect = 0.008
Identities = 15/18 (83%), Positives = 15/18 (83%)
Query: 228 GPGLPPPPPPLPPPGPPP 245
G LPPPPPPLPP GPPP
Sbjct: 559 GGMLPPPPPPLPPGGPPP 576
Score = 34.3 bits (77), Expect = 0.26
Identities = 18/28 (64%), Positives = 18/28 (64%), Gaps = 7/28 (25%)
Query: 226 SSGPGL---PPPPPPLP----PPGPPPL 246
SS PG PPPPPPLP PP PPPL
Sbjct: 542 SSVPGSLLPPPPPPPLPGGMLPPPPPPL 569
>gi|33286436 gametogenetin [Homo sapiens]
Length = 652
Score = 39.3 bits (90), Expect = 0.008
Identities = 32/106 (30%), Positives = 39/106 (36%), Gaps = 20/106 (18%)
Query: 229 PGLPPPP-----PPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDD 283
P P PP PPLPPP PPP + + P L T GL H
Sbjct: 426 PMRPGPPGLQELPPLPPPTPPPTLQPPALQPTPLPVAPPL----------TPGLGHKESA 475
Query: 284 QKTYKNPSLRAQGGQTQSPTKSHTPSPT-----SPKSYPSQKHAPV 324
P+L Q+P S P+PT P S P+ AP+
Sbjct: 476 LAPTAAPALPPALAADQAPAPSPAPAPTVAEPSPPVSAPAPAAAPI 521
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 38.9 bits (89), Expect = 0.010
Identities = 16/21 (76%), Positives = 18/21 (85%), Gaps = 1/21 (4%)
Query: 225 LSSGPGLPPPPPPLPPPGPPP 245
+S+GP LPPPPPP PPP PPP
Sbjct: 674 VSAGPPLPPPPPP-PPPLPPP 693
Score = 36.2 bits (82), Expect = 0.067
Identities = 16/36 (44%), Positives = 18/36 (50%)
Query: 228 GPGLPPPPPPLPPPGPPPLFENEGKKEESSPSRSAL 263
GP PPPP L PP PP LF G P + A+
Sbjct: 718 GPPPAPPPPGLAPPPPPGLFFGLGSSSSQCPRKPAI 753
Score = 35.4 bits (80), Expect = 0.11
Identities = 16/27 (59%), Positives = 17/27 (62%), Gaps = 7/27 (25%)
Query: 226 SSGPGLPPPPPPLP-------PPGPPP 245
S+GP PPPPPPLP P GPPP
Sbjct: 695 SAGPPPPPPPPPLPNSPAPPNPGGPPP 721
>gi|4885193 AT rich interactive domain 3A (BRIGHT- like) protein
[Homo sapiens]
Length = 593
Score = 38.9 bits (89), Expect = 0.010
Identities = 33/119 (27%), Positives = 48/119 (40%), Gaps = 6/119 (5%)
Query: 233 PPPPPLPPPGPPPLFENEGKKEESSPSRSALFAQLNQGEAITKGLRHVTDDQKTYKNPSL 292
PP PP PPG +E ++ ES+ + A A L A GL H + P
Sbjct: 28 PPDPPAAPPGRARAAPDEDREPESARMQRAQMAALAAMRAAAAGLGHPASPGGSEDGP-- 85
Query: 293 RAQGGQTQSPTKSHTP-SPTSPKSYPSQKH-APVLELEGKKWRVEYQEDRNDLVISETE 349
G + + + TP SP + P ++H + E K + E +E DL E E
Sbjct: 86 --PGSEEEDAAREGTPGSPGRGREGPGEEHFEDMASDEDMKPKWEEEEMEEDLGEDEEE 142
>gi|6382071 diaphanous 2 isoform 12C [Homo sapiens]
Length = 1096
Score = 38.9 bits (89), Expect = 0.010
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
Query: 194 ELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLP-----PPGPPPL 246
EL+A I++ T S + + +A + GP PPP PPLP PP PPPL
Sbjct: 527 ELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPL 584
Score = 36.6 bits (83), Expect = 0.051
Identities = 17/28 (60%), Positives = 17/28 (60%), Gaps = 6/28 (21%)
Query: 225 LSSGPGLPPPPPPLP------PPGPPPL 246
L G LPPPPPPLP PP PPPL
Sbjct: 571 LPGGAPLPPPPPPLPGMMGIPPPPPPPL 598
Score = 30.4 bits (67), Expect = 3.7
Identities = 13/18 (72%), Positives = 13/18 (72%), Gaps = 3/18 (16%)
Query: 232 PPPPPPL---PPPGPPPL 246
PPPPPPL PP PPPL
Sbjct: 592 PPPPPPLLFGGPPPPPPL 609
Score = 29.3 bits (64), Expect = 8.2
Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 21/148 (14%)
Query: 230 GLPPPPPPL---PPPGPPPLFENEGKKEESSPSRSALFAQLN----QGEAITKGLRHVTD 282
G PPPPPPL PPP L G K++ ++N + +++ +
Sbjct: 601 GGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWLRV 660
Query: 283 DQKTYKNPSLRAQ---GGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKK-------- 331
+ ++NP L A+ TQ + + + K+ P++K L + K
Sbjct: 661 KEDKFENPDLFAKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIF 720
Query: 332 ---WRVEYQEDRNDLVISETELKQVAYI 356
+R+ Y++ RN ++ ++ A I
Sbjct: 721 LGSYRMPYEDIRNVILEVNEDMLSEALI 748
>gi|5803003 diaphanous 2 isoform 156 [Homo sapiens]
Length = 1101
Score = 38.9 bits (89), Expect = 0.010
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 5/58 (8%)
Query: 194 ELQAYIKEHHTTGLTWSKTGPVASTVSAFSVLSSGPGLPPPPPPLP-----PPGPPPL 246
EL+A I++ T S + + +A + GP PPP PPLP PP PPPL
Sbjct: 527 ELEAEIQQLRTQAQVLSSSSGIPGPPAAPPLPGVGPPPPPPAPPLPGGAPLPPPPPPL 584
Score = 36.6 bits (83), Expect = 0.051
Identities = 17/28 (60%), Positives = 17/28 (60%), Gaps = 6/28 (21%)
Query: 225 LSSGPGLPPPPPPLP------PPGPPPL 246
L G LPPPPPPLP PP PPPL
Sbjct: 571 LPGGAPLPPPPPPLPGMMGIPPPPPPPL 598
Score = 30.4 bits (67), Expect = 3.7
Identities = 13/18 (72%), Positives = 13/18 (72%), Gaps = 3/18 (16%)
Query: 232 PPPPPPL---PPPGPPPL 246
PPPPPPL PP PPPL
Sbjct: 592 PPPPPPLLFGGPPPPPPL 609
Score = 29.3 bits (64), Expect = 8.2
Identities = 32/148 (21%), Positives = 60/148 (40%), Gaps = 21/148 (14%)
Query: 230 GLPPPPPPL---PPPGPPPLFENEGKKEESSPSRSALFAQLN----QGEAITKGLRHVTD 282
G PPPPPPL PPP L G K++ ++N + +++ +
Sbjct: 601 GGPPPPPPLGGVPPPPGISLNLPYGMKQKKMYKPEVSMKRINWSKIEPTELSENCFWLRV 660
Query: 283 DQKTYKNPSLRAQ---GGQTQSPTKSHTPSPTSPKSYPSQKHAPVLELEGKK-------- 331
+ ++NP L A+ TQ + + + K+ P++K L + K
Sbjct: 661 KEDKFENPDLFAKLALNFATQIKVQKNAEALEEKKTGPTKKKVKELRILDPKTAQNLSIF 720
Query: 332 ---WRVEYQEDRNDLVISETELKQVAYI 356
+R+ Y++ RN ++ ++ A I
Sbjct: 721 LGSYRMPYEDIRNVILEVNEDMLSEALI 748
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,054,526
Number of Sequences: 37866
Number of extensions: 1139277
Number of successful extensions: 21706
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 411
Number of HSP's successfully gapped in prelim test: 354
Number of HSP's that attempted gapping in prelim test: 11692
Number of HSP's gapped (non-prelim): 6409
length of query: 477
length of database: 18,247,518
effective HSP length: 106
effective length of query: 371
effective length of database: 14,233,722
effective search space: 5280710862
effective search space used: 5280710862
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.