Guide to the Human Genome
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Search of human proteins with 5453545

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5453545 STAM binding protein [Homo sapiens]
         (424 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47132534 STAM binding protein [Homo sapiens]                       855   0.0  
gi|42519912 STAM binding protein [Homo sapiens]                       855   0.0  
gi|5453545 STAM binding protein [Homo sapiens]                        855   0.0  
gi|33147080 STAM binding protein-like 1 [Homo sapiens]                489   e-138
gi|116174778 centrosome spindle pole associated protein 1 isofor...    47   4e-05
gi|116174789 centrosome spindle pole associated protein 1 isofor...    47   4e-05
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       46   7e-05
gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]             45   1e-04
gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]             45   1e-04
gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]             45   1e-04
gi|22035606 mitogen-activated protein kinase kinase kinase kinas...    45   2e-04
gi|22035602 mitogen-activated protein kinase kinase kinase kinas...    45   2e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    44   2e-04
gi|215982794 myosin VA isoform 2 [Homo sapiens]                        44   2e-04
gi|215982791 myosin VA isoform 1 [Homo sapiens]                        44   2e-04
gi|22035604 mitogen-activated protein kinase kinase kinase kinas...    44   3e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          44   4e-04
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]        44   4e-04
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    43   5e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             43   5e-04
gi|148746195 trichohyalin [Homo sapiens]                               43   6e-04
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ...    43   6e-04
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    41   0.002
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    41   0.002
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    41   0.002
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    41   0.002
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    41   0.002
gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo...    41   0.002
gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo...    41   0.002
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    41   0.002

>gi|47132534 STAM binding protein [Homo sapiens]
          Length = 424

 Score =  855 bits (2208), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60
           MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF
Sbjct: 1   MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60

Query: 61  ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120
           ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE
Sbjct: 61  ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120

Query: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
           YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK
Sbjct: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180

Query: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240
           IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG
Sbjct: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240

Query: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300
           ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL
Sbjct: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300

Query: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360
           IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP
Sbjct: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360

Query: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420
           ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI
Sbjct: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420

Query: 421 TDLR 424
           TDLR
Sbjct: 421 TDLR 424


>gi|42519912 STAM binding protein [Homo sapiens]
          Length = 424

 Score =  855 bits (2208), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60
           MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF
Sbjct: 1   MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60

Query: 61  ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120
           ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE
Sbjct: 61  ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120

Query: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
           YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK
Sbjct: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180

Query: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240
           IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG
Sbjct: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240

Query: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300
           ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL
Sbjct: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300

Query: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360
           IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP
Sbjct: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360

Query: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420
           ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI
Sbjct: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420

Query: 421 TDLR 424
           TDLR
Sbjct: 421 TDLR 424


>gi|5453545 STAM binding protein [Homo sapiens]
          Length = 424

 Score =  855 bits (2208), Expect = 0.0
 Identities = 424/424 (100%), Positives = 424/424 (100%)

Query: 1   MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60
           MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF
Sbjct: 1   MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60

Query: 61  ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120
           ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE
Sbjct: 61  ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120

Query: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
           YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK
Sbjct: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180

Query: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240
           IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG
Sbjct: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240

Query: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300
           ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL
Sbjct: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300

Query: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360
           IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP
Sbjct: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360

Query: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420
           ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI
Sbjct: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420

Query: 421 TDLR 424
           TDLR
Sbjct: 421 TDLR 424


>gi|33147080 STAM binding protein-like 1 [Homo sapiens]
          Length = 436

 Score =  489 bits (1260), Expect = e-138
 Identities = 240/430 (55%), Positives = 314/430 (73%), Gaps = 15/430 (3%)

Query: 1   MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60
           M DH DVSL PE+RVRALS+LG  + ++EDI PRRYFRSGVE+ RMAS+Y EEGN+E+AF
Sbjct: 16  MPDHTDVSLSPEERVRALSKLGCNITISEDITPRRYFRSGVEMERMASVYLEEGNLENAF 75

Query: 61  ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120
           +LYNK+ITLF+EKLP HRDY+   +PEK+D +KKLKEIAFP+ +ELK +LLK+Y  EY E
Sbjct: 76  VLYNKFITLFVEKLPNHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKNDLLKKYNVEYQE 135

Query: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
           Y + K K   E+ + +  Q+ +E E++R+AQ +QQQLE EQF  FE+ ++ QEL + +++
Sbjct: 136 YLQSKNKYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFFEDQLKKQELARGQMR 195

Query: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPT------LTVSSIQPSDCHTTVRPAKPPVVD 234
             Q  G         L   ++  +L  F T      L V + QP+    T   +  P V+
Sbjct: 196 SQQTSG---------LSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYASHSPPVN 246

Query: 235 RSLKPGALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEF 294
           R+L P A  ++     ++GLR VV+P  LC +FLQLA +NT RG+ETCGILCGKL  NEF
Sbjct: 247 RALTPAATLSAVQNLVVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGKLTHNEF 306

Query: 295 TITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCS 354
           TITHV++PKQSAG DYC+ EN EELF +QDQ  L+TLGWIHTHPTQTAFLSSVDLHTHCS
Sbjct: 307 TITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVDLHTHCS 366

Query: 355 YQMMLPESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVV 414
           YQ+MLPE++AIVCSPK ++TG F+LT+ G+ E+S+C++KGFHPH+K+P LF  C HV V 
Sbjct: 367 YQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSICKHVLVK 426

Query: 415 DRAVTITDLR 424
           D  + + DLR
Sbjct: 427 DIKIIVLDLR 436


>gi|116174778 centrosome spindle pole associated protein 1 isoform b
           [Homo sapiens]
          Length = 1221

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 12/172 (6%)

Query: 69  LFIEKLPKHRDYKSAVIPEKKDTVKKLKE---IAFPKAEELKAELLKRYTKEYTEYNEEK 125
           L I++   ++++    I EKK   +  +E   IA  K E   AE   R  +EY E  E+K
Sbjct: 727 LQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKK 786

Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEF 185
           +++ EE          L +E+Q+ A++K+++ E++     +       L  E  K +++ 
Sbjct: 787 REKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQP 846

Query: 186 GKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCH--TTVRPAKPPVVDR 235
             + P L   +   L++P        +V SI  S  H  +  R   PPV  R
Sbjct: 847 SPIVPALQNKIASKLQRPP-------SVDSIIRSFIHESSMSRAQSPPVPAR 891


>gi|116174789 centrosome spindle pole associated protein 1 isoform a
           [Homo sapiens]
          Length = 1256

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 12/172 (6%)

Query: 69  LFIEKLPKHRDYKSAVIPEKKDTVKKLKE---IAFPKAEELKAELLKRYTKEYTEYNEEK 125
           L I++   ++++    I EKK   +  +E   IA  K E   AE   R  +EY E  E+K
Sbjct: 762 LQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKK 821

Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEF 185
           +++ EE          L +E+Q+ A++K+++ E++     +       L  E  K +++ 
Sbjct: 822 REKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQP 881

Query: 186 GKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCH--TTVRPAKPPVVDR 235
             + P L   +   L++P        +V SI  S  H  +  R   PPV  R
Sbjct: 882 SPIVPALQNKIASKLQRPP-------SVDSIIRSFIHESSMSRAQSPPVPAR 926


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 7/105 (6%)

Query: 87  EKKDTVKKLKEIAFPKAEE---LKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE 143
           E++D  +   E A  +AEE   +KAE  K+   E      E+K  A+E  R  A ++E  
Sbjct: 258 EEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERM 317

Query: 144 KEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEK----ERLKIVQE 184
           +E+++ A +++Q++++E+  A EE  R +E EK    ER +I +E
Sbjct: 318 REEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEE 362



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 26/93 (27%), Positives = 58/93 (62%), Gaps = 9/93 (9%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           E+++ +++ ++ A  + + +K E  KR  +E     EE+K+ AEE       +Q +++E+
Sbjct: 312 EERERMREEEKRAAEERQRIKEEE-KRAAEERQRIKEEEKRAAEE-------RQRIKEEE 363

Query: 147 QRVAQQKQQ-QLEQEQFHAFEEMIRNQELEKER 178
           +R A+++Q+ + E+E+    EE  RN++LE+++
Sbjct: 364 KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK 396



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 29/113 (25%), Positives = 63/113 (55%), Gaps = 9/113 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           E+  K  D ++ +  E+K   ++ +     + E ++ E  KR  +E     EE+K+ AEE
Sbjct: 283 EQDKKIADERARIEAEEKAAAQERERREAEERERMREEE-KRAAEERQRIKEEEKRAAEE 341

Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
                  +Q +++E++R A+++ Q++++E+  A EE  R +  E+E+ K+ ++
Sbjct: 342 -------RQRIKEEEKRAAEER-QRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/92 (30%), Positives = 54/92 (58%), Gaps = 6/92 (6%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           E++  +K+ ++ A  + + +K E  KR  +E     EE+K+ AEE  R  A     E+EK
Sbjct: 326 EERQRIKEEEKRAAEERQRIKEEE-KRAAEERQRIKEEEKRAAEERQRARAE----EEEK 380

Query: 147 QRVAQQKQQQLEQEQFHAFEE-MIRNQELEKE 177
            +V +QK+ +  +E+ HA +E  I+ +++E++
Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQK 412



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 5/113 (4%)

Query: 79  DYKSAVIPEKKDTVKKLKEIAFPKAEELKAEL--LKRYTKEYTEYNEEKKKEAEELARNM 136
           D K A    + +  K+L+E+   + E    E   LK+  +E     EE KK+ EE  R  
Sbjct: 520 DTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE--RRK 577

Query: 137 AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVD 189
            +++E ++ KQ  A +K ++ E+E+    EE+ R +    E+ + + E G  D
Sbjct: 578 VLEEEEQRRKQEEADRKLRE-EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSD 629



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 20/90 (22%), Positives = 47/90 (52%), Gaps = 3/90 (3%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           ++L + R  +     E+ + +K+ ++ A  + EELK    KR  +      EE++++ EE
Sbjct: 534 KRLEELRRRRGETESEEFEKLKQKQQEAALELEELKK---KREERRKVLEEEEQRRKQEE 590

Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161
             R +  ++E  + K+ + +++ +  E+ Q
Sbjct: 591 ADRKLREEEEKRRLKEEIERRRAEAAEKRQ 620



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 24/119 (20%), Positives = 56/119 (47%), Gaps = 6/119 (5%)

Query: 71  IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK---- 126
           + K  +  D++ A   +K+D  K+ +E   PK   +    ++   +E T  ++E+     
Sbjct: 168 VTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMS 227

Query: 127 -KEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
            K  +  +     ++E E+    ++  ++ + E+++  A  E  R +  E+ER+K  Q+
Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKME-EEDKERAEAERARLEAEERERIKAEQD 285



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 21/107 (19%), Positives = 56/107 (52%), Gaps = 13/107 (12%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           EK       ++  + EKK  +++ K     K E+++ ++  ++  E         K+A+E
Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQETKI----KGEKVEQKIEGKWVNE---------KKAQE 425

Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
                A+ ++  +EK    Q K+++L++++    +E I++++++K++
Sbjct: 426 DKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 472


>gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 12/135 (8%)

Query: 17  ALSQLGSAVEVN-EDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLF--IEK 73
           +L  L    EV  E I  + Y  S ++I + A     + + E A++LY KY+T++  I+K
Sbjct: 16  SLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKK 75

Query: 74  LP---KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
            P   + +DY  +++      +KK    A  +AE L   L  RY +       E+K   E
Sbjct: 76  RPDFKQQQDYFHSIL--GPGNIKK----AVEEAERLSESLKLRYEEAEVRKKLEEKDRQE 129

Query: 131 ELARNMAIQQELEKE 145
           E  R    +QE  +E
Sbjct: 130 EAQRLQQKRQETGRE 144



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 7/122 (5%)

Query: 84  VIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE-L 142
           VIP++       K + F     L  E   R   E     E+ K+E E   R    Q+E L
Sbjct: 440 VIPDRST-----KPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKL 494

Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLEK 202
            KE+Q    +K+Q+ E+ +    ++  + +E+EK+  +  ++  K      G  +  +++
Sbjct: 495 RKEEQEQKAKKKQEAEENEITEKQQKAK-EEMEKKESEQAKKEDKETSAKRGKEITGVKR 553

Query: 203 PS 204
            S
Sbjct: 554 QS 555


>gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 12/135 (8%)

Query: 17  ALSQLGSAVEVN-EDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLF--IEK 73
           +L  L    EV  E I  + Y  S ++I + A     + + E A++LY KY+T++  I+K
Sbjct: 16  SLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKK 75

Query: 74  LP---KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
            P   + +DY  +++      +KK    A  +AE L   L  RY +       E+K   E
Sbjct: 76  RPDFKQQQDYFHSIL--GPGNIKK----AVEEAERLSESLKLRYEEAEVRKKLEEKDRQE 129

Query: 131 ELARNMAIQQELEKE 145
           E  R    +QE  +E
Sbjct: 130 EAQRLQQKRQETGRE 144



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 7/122 (5%)

Query: 84  VIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE-L 142
           VIP++       K + F     L  E   R   E     E+ K+E E   R    Q+E L
Sbjct: 440 VIPDRST-----KPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKL 494

Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLEK 202
            KE+Q    +K+Q+ E+ +    ++  + +E+EK+  +  ++  K      G  +  +++
Sbjct: 495 RKEEQEQKAKKKQEAEENEITEKQQKAK-EEMEKKESEQAKKEDKETSAKRGKEITGVKR 553

Query: 203 PS 204
            S
Sbjct: 554 QS 555


>gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens]
          Length = 1118

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 12/135 (8%)

Query: 17  ALSQLGSAVEVN-EDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLF--IEK 73
           +L  L    EV  E I  + Y  S ++I + A     + + E A++LY KY+T++  I+K
Sbjct: 16  SLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKK 75

Query: 74  LP---KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
            P   + +DY  +++      +KK    A  +AE L   L  RY +       E+K   E
Sbjct: 76  RPDFKQQQDYFHSIL--GPGNIKK----AVEEAERLSESLKLRYEEAEVRKKLEEKDRQE 129

Query: 131 ELARNMAIQQELEKE 145
           E  R    +QE  +E
Sbjct: 130 EAQRLQQKRQETGRE 144



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 7/122 (5%)

Query: 84  VIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE-L 142
           VIP++       K + F     L  E   R   E     E+ K+E E   R    Q+E L
Sbjct: 440 VIPDRST-----KPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKL 494

Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLEK 202
            KE+Q    +K+Q+ E+ +    ++  + +E+EK+  +  ++  K      G  +  +++
Sbjct: 495 RKEEQEQKAKKKQEAEENEITEKQQKAK-EEMEKKESEQAKKEDKETSAKRGKEITGVKR 553

Query: 203 PS 204
            S
Sbjct: 554 QS 555


>gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 3 [Homo sapiens]
          Length = 1212

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 29/116 (25%), Positives = 66/116 (56%), Gaps = 10/116 (8%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIA--FPKAEELKAELLKRYTKEYTEYNEEKKKEA 129
           ++L +  +YK  ++ E++  +++ KE      + +  + E  ++  +E     +E+K+  
Sbjct: 379 QQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRL 438

Query: 130 EELARNMAIQQE---LEKEKQRVAQQKQ---QQLEQEQFHAFEEMIRNQELEKERL 179
           EEL R    ++E    E+EK+RV ++++   +QLE+EQ H   E+++ Q L+++ +
Sbjct: 439 EELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL--EVLQQQLLQEQAM 492



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 8/95 (8%)

Query: 95  LKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQ 154
           L+E    + EE K +LL    K   +  E++++  E        QQ  E+E +R  +++Q
Sbjct: 376 LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE--------QQRREREARRQQEREQ 427

Query: 155 QQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVD 189
           ++ EQE+    EE+ R ++ E+ER +  +E  +V+
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/113 (19%), Positives = 56/113 (49%), Gaps = 8/113 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           E++P+     S+++    ++  +   +   +  + ++E L+R         E++ +E EE
Sbjct: 331 EEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQL----LQEQQLREQEE 386

Query: 132 LARNMAIQQ----ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
             R +  ++    E +KE++R  +++Q++  + +     E  R ++ EK RL+
Sbjct: 387 YKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439


>gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 1 [Homo sapiens]
          Length = 1166

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 29/116 (25%), Positives = 66/116 (56%), Gaps = 10/116 (8%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIA--FPKAEELKAELLKRYTKEYTEYNEEKKKEA 129
           ++L +  +YK  ++ E++  +++ KE      + +  + E  ++  +E     +E+K+  
Sbjct: 379 QQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRL 438

Query: 130 EELARNMAIQQE---LEKEKQRVAQQKQ---QQLEQEQFHAFEEMIRNQELEKERL 179
           EEL R    ++E    E+EK+RV ++++   +QLE+EQ H   E+++ Q L+++ +
Sbjct: 439 EELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL--EVLQQQLLQEQAM 492



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 8/95 (8%)

Query: 95  LKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQ 154
           L+E    + EE K +LL    K   +  E++++  E        QQ  E+E +R  +++Q
Sbjct: 376 LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE--------QQRREREARRQQEREQ 427

Query: 155 QQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVD 189
           ++ EQE+    EE+ R ++ E+ER +  +E  +V+
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/113 (19%), Positives = 56/113 (49%), Gaps = 8/113 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           E++P+     S+++    ++  +   +   +  + ++E L+R         E++ +E EE
Sbjct: 331 EEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQL----LQEQQLREQEE 386

Query: 132 LARNMAIQQ----ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
             R +  ++    E +KE++R  +++Q++  + +     E  R ++ EK RL+
Sbjct: 387 YKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 9/104 (8%)

Query: 72  EKLPKHRDYKSAVIPEKK--DTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEA 129
           E++ K R+ K     EKK  D  +K++E      E ++    K   +E T   +E+K + 
Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQE-----EERIREREKKMREEEETMREQEEKMQK 475

Query: 130 EELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173
           +E   NM  Q+E E ++QR+ +QK++  EQE+    EE I  QE
Sbjct: 476 QE--ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 26/114 (22%), Positives = 55/114 (48%), Gaps = 1/114 (0%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           EKLP     KS +    K+  +KL+   F   +     L +   ++  E  E++KK  ++
Sbjct: 232 EKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ 291

Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQE-QFHAFEEMIRNQELEKERLKIVQE 184
             +    ++ L +++ ++ +Q+++   QE +    E+ +R QE E    K ++E
Sbjct: 292 EEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 26/105 (24%), Positives = 58/105 (55%), Gaps = 7/105 (6%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK-----KEAEELARNMAIQQE 141
           E++  ++K +E  + + E L+ +  K   +E   + +EK+     KE  E  + +  Q+E
Sbjct: 283 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE 342

Query: 142 LEKEKQRVAQQKQQQLEQEQ--FHAFEEMIRNQELEKERLKIVQE 184
           L ++++++ +Q+++  EQE+      E+M R +E   E+ K ++E
Sbjct: 343 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 387



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 25/120 (20%), Positives = 59/120 (49%), Gaps = 3/120 (2%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEI---AFPKAEELKAELLKRYTKEYTEYNEEKKKE 128
           E+  K RD +  +  +++   KK +E     + + E+++ E   R  ++     EE  +E
Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607

Query: 129 AEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188
            EE  +    + + ++EK    ++K Q+ E++ +   E+M   +E   E+ ++ ++  K+
Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 31/114 (27%), Positives = 62/114 (54%), Gaps = 7/114 (6%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           E+  K R+ +  +  ++K   ++ KE+   + +EL+ +   R  +E  +  EEK  E EE
Sbjct: 304 EQEGKMREQEEKMWRQEKRLREQEKELR-EQEKELREQKELREQEEQMQEQEEKMWEQEE 362

Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQ-FHAFEEMIRNQELEKERLKIVQE 184
             R    ++++ ++++R+ +Q++Q  EQEQ     EE +  Q+   ERL+  +E
Sbjct: 363 KMREQ--EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD---ERLREKEE 411



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 23/98 (23%), Positives = 53/98 (54%), Gaps = 2/98 (2%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           EK++ +++ +E  + + E+++ E   +  ++ T   EEK +E EE  R    +   E+E 
Sbjct: 408 EKEERMRE-QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEET 465

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
            R  ++K Q+ E+  +   E+  + Q L +++ K+ ++
Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 28/118 (23%), Positives = 66/118 (55%), Gaps = 14/118 (11%)

Query: 85  IPEKKDTV---KKLKEIAFPKAEELKA---ELLKRYTKEYTE--YNEEKKKEAE---ELA 133
           +PE+K+ +   +K++E    + +E K    E +++ T+E  +  +++EK +E E   E  
Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719

Query: 134 RNMAIQQEL---EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188
           + M  ++E+   ++EK +  ++K Q+ E+E +   E+M   +E   E+ ++ ++  K+
Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 10/111 (9%)

Query: 71  IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
           +EK  + ++ K+    EK    ++++E      EE   E + R  +E  +  EEK +E E
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREE---EEMMREQEEKMQEQEEKMQEQE 623

Query: 131 ELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181
           E  +    +++++++++++ +Q+++  EQE     E+M   Q L +++ K+
Sbjct: 624 E--KMWEQEEKMQEQEEKMWEQEEKMWEQE-----EKMWEQQRLPEQKEKL 667



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 23/96 (23%), Positives = 55/96 (57%), Gaps = 4/96 (4%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           E+++ +++ +E    + E+++ +  K + +E  E  +E++++  E    M  Q+E   E+
Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQE--EKMQEQEEKMWEQEEKMWEQEEKMWEQ 657

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE--LEKERLK 180
           QR+ +QK++  E E+    E+M   +E   E+E+++
Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 13/96 (13%)

Query: 89  KDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQR 148
           ++  KK++E      EE+  E  ++  +E  E  +E+++E  E    M  Q+E   E+QR
Sbjct: 716 REREKKMRE-----EEEMMREQEEKM-QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769

Query: 149 VAQQK------QQQLEQEQFHAFEEMIRNQELEKER 178
           + +QK      ++  EQE+    EE +R+QE EK R
Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE-EKMR 804



 Score = 32.3 bits (72), Expect = 0.84
 Identities = 23/93 (24%), Positives = 53/93 (56%), Gaps = 9/93 (9%)

Query: 87  EKKDTVKKLKEIAFPKAEE------LKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQ 140
           E+++ ++K +E  + + E+      L  +  K + +E  +  EEK  E EE  R+   Q+
Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD---QE 524

Query: 141 ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173
           E+  +++++ +Q++ + +++Q    EE +R+QE
Sbjct: 525 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 27/119 (22%), Positives = 57/119 (47%), Gaps = 12/119 (10%)

Query: 76  KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARN 135
           + ++++   +PE+K+  K  ++    + EE   E  ++   +   + +EKK   +E  R 
Sbjct: 484 EEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541

Query: 136 MAIQQELEKEKQRVAQQ----------KQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
              Q   ++EK R  +Q          K+ Q ++++    EE +R +E  +ER K ++E
Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 20/102 (19%), Positives = 47/102 (46%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           EK+ +  D       + +D  +K+ +      ++ + +  K + +E     EE+ +E E+
Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596

Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173
             R        ++EK +  ++K Q+ E++ +   E+M   +E
Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 24/103 (23%), Positives = 54/103 (52%), Gaps = 3/103 (2%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           E++  +++ KE+   + +  + E      +E     EEK    EE  R    ++++ +++
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE--RLWEQEKQMREQE 389

Query: 147 QRVAQQKQQQLEQ-EQFHAFEEMIRNQELEKERLKIVQEFGKV 188
           Q++  Q+++  EQ E+    EE +R QE   E+++ ++E  K+
Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 14/111 (12%)

Query: 82  SAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE 141
           SAV    K   + ++E+     +E  A  L+ Y    T  NEE KK+  EL   + + + 
Sbjct: 186 SAVSTRHKKADRYIEELT----KERDALSLELYRNTIT--NEELKKKNAELQEKLPLAES 239

Query: 142 LEKEKQRVAQQKQQQLEQEQF--------HAFEEMIRNQELEKERLKIVQE 184
            + E Q   ++ +++LE+ +F           EEM R +E  +E+ K +++
Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 290



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 19/100 (19%), Positives = 55/100 (55%), Gaps = 6/100 (6%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYT--EYNEEKKKEAEELARNMAIQQELEK 144
           E+++ + + +E  + + ++++ +  K   +E    E +E  +++ E +     + +++EK
Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425

Query: 145 EKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
            ++    Q+Q++  ++Q    EE ++ +E  +ER K ++E
Sbjct: 426 MREEKKMQEQEKKTRDQ----EEKMQEEERIREREKKMRE 461



 Score = 28.9 bits (63), Expect = 9.2
 Identities = 18/87 (20%), Positives = 47/87 (54%), Gaps = 3/87 (3%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           E+++ +++ +E  + + E++  +  K + ++     +EK  E E++     I ++ EK +
Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE 173
               Q+++ + ++E+    EE +R QE
Sbjct: 798 D---QEEKMRGQEEKMRGQEEKMRGQE 821


>gi|215982794 myosin VA isoform 2 [Homo sapiens]
          Length = 1828

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 14/133 (10%)

Query: 82   SAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE 141
            S+ I E +D   + +E +  K   L   L  +  K  TE  +EK+           +Q E
Sbjct: 1127 SSEIAEMEDIPSRTEEPSEKKVP-LDMSLFLKLQKRVTELEQEKQ----------VMQDE 1175

Query: 142  LEKEKQRVAQQKQQQLEQEQFHAFE---EMIRNQELEKERLKIVQEFGKVDPGLGGPLVP 198
            L++++++V + K ++ E+ Q    E   E ++ QELE E  K+  E  ++   L     P
Sbjct: 1176 LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAP 1235

Query: 199  DLEKPSLDVFPTL 211
            ++  P    +  L
Sbjct: 1236 EVTAPGAPAYRVL 1248



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 21/79 (26%), Positives = 41/79 (51%), Gaps = 9/79 (11%)

Query: 120  EYNEEKKKEAEELARNM-----AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQ-E 173
            E+ +  K+E E+L  N+      ++QE E    R+ QQ ++  E  +    EE  + + +
Sbjct: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELD 1070

Query: 174  LEKERLK---IVQEFGKVD 189
            L  ERL+   ++ EF +++
Sbjct: 1071 LNDERLRYQNLLNEFSRLE 1089


>gi|215982791 myosin VA isoform 1 [Homo sapiens]
          Length = 1855

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 14/133 (10%)

Query: 82   SAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE 141
            S+ I E +D   + +E +  K   L   L  +  K  TE  +EK+           +Q E
Sbjct: 1127 SSEIAEMEDIPSRTEEPSEKKVP-LDMSLFLKLQKRVTELEQEKQ----------VMQDE 1175

Query: 142  LEKEKQRVAQQKQQQLEQEQFHAFE---EMIRNQELEKERLKIVQEFGKVDPGLGGPLVP 198
            L++++++V + K ++ E+ Q    E   E ++ QELE E  K+  E  ++   L     P
Sbjct: 1176 LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAP 1235

Query: 199  DLEKPSLDVFPTL 211
            ++  P    +  L
Sbjct: 1236 EVTAPGAPAYRVL 1248



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 21/79 (26%), Positives = 41/79 (51%), Gaps = 9/79 (11%)

Query: 120  EYNEEKKKEAEELARNM-----AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQ-E 173
            E+ +  K+E E+L  N+      ++QE E    R+ QQ ++  E  +    EE  + + +
Sbjct: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELD 1070

Query: 174  LEKERLK---IVQEFGKVD 189
            L  ERL+   ++ EF +++
Sbjct: 1071 LNDERLRYQNLLNEFSRLE 1089


>gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4
           isoform 2 [Homo sapiens]
          Length = 1320

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 8/95 (8%)

Query: 95  LKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQ 154
           L+E    + EE K +LL    K   +  E++++  E        QQ  E+E +R  +++Q
Sbjct: 376 LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE--------QQRREREARRQQEREQ 427

Query: 155 QQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVD 189
           ++ EQE+    EE+ R ++ E+ER +  +E  +V+
Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462



 Score = 35.4 bits (80), Expect = 0.099
 Identities = 33/140 (23%), Positives = 65/140 (46%), Gaps = 28/140 (20%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIA--FPKAEELKAELLKRYTKEYTEYNEEKKKEA 129
           ++L +  +YK  ++ E++  +++ KE      + +  + E  ++  +E     +E+K+  
Sbjct: 379 QQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRL 438

Query: 130 EELARNMA---------------------IQQELEKEKQRVAQQKQQQLEQEQFHAFE-- 166
           EEL R                        I+++LE E+QR  +  QQQL QEQ    E  
Sbjct: 439 EELERRRKEEEERRRAEEEKRRVEREQEYIRRQLE-EEQRHLEVLQQQLLQEQAMLLECR 497

Query: 167 --EMIRNQELEKERLKIVQE 184
             EM  +++ E+ + ++ QE
Sbjct: 498 WREMEEHRQAERLQRQLQQE 517



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 11/86 (12%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYN----EEKKKEAEELARNMAIQQEL 142
           E+K  +++L+     + E  +AE  KR  +   EY     EE+++  E L + +  +Q +
Sbjct: 433 EEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492

Query: 143 -------EKEKQRVAQQKQQQLEQEQ 161
                  E E+ R A++ Q+QL+QEQ
Sbjct: 493 LLECRWREMEEHRQAERLQRQLQQEQ 518



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 22/113 (19%), Positives = 56/113 (49%), Gaps = 8/113 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           E++P+     S+++    ++  +   +   +  + ++E L+R         E++ +E EE
Sbjct: 331 EEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQL----LQEQQLREQEE 386

Query: 132 LARNMAIQQ----ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
             R +  ++    E +KE++R  +++Q++  + +     E  R ++ EK RL+
Sbjct: 387 YKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 41/171 (23%), Positives = 77/171 (45%), Gaps = 18/171 (10%)

Query: 72  EKLPKHRDYKSAVIPE-----KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK 126
           E+ PK  + K  V  E     KK+  K++K+   PK  E+K E+ K   KE  +  +E K
Sbjct: 672 EEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPK--EVKKEVKKEEKKEVKKEEKEPK 729

Query: 127 KEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFG 186
           KE ++L ++         E ++ A  K +  ++E+    + +   +  EK ++K++++ G
Sbjct: 730 KEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEG 789

Query: 187 KVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSL 237
           K             E  +  V    T +++  +     + PAK    +RSL
Sbjct: 790 KA-----------AEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSL 829



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 22/87 (25%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 76  KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEK--KKEAEELA 133
           K  D K      KK+  KK  +    K E+ K E +K+  K+  +  E+K  KKE ++  
Sbjct: 645 KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704

Query: 134 RNMAIQQELEKEKQRVAQQKQQQLEQE 160
               +++E++KE+++  ++++++ ++E
Sbjct: 705 PPKEVKKEVKKEEKKEVKKEEKEPKKE 731



 Score = 32.7 bits (73), Expect = 0.64
 Identities = 39/167 (23%), Positives = 75/167 (44%), Gaps = 19/167 (11%)

Query: 86  PEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE-YNEEKKKEAEELAR---NMAIQQE 141
           P K +  +K      PKA   K + +K+ TK   E   EEK+K  +E+A+      I++E
Sbjct: 615 PVKAEVAEKQATDVKPKAA--KEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKE 672

Query: 142 LEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLE 201
            + +K+ V ++ ++++++E+    ++ ++ +   KE  K V++  K +       V   E
Sbjct: 673 EKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKE-------VKKEE 725

Query: 202 KPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPGALSNSESI 248
           K      P   +  + P D   +  P        +LKP      ES+
Sbjct: 726 KE-----PKKEIKKL-PKDAKKSSTPLSEAKKPAALKPKVPKKEESV 766



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 1/131 (0%)

Query: 75  PKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELAR 134
           PK    K+     K     K +E   PK E  K E      KE     EE KKE ++  +
Sbjct: 630 PKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIK 689

Query: 135 NMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGG 194
               ++E +KE ++    K+ + E ++    E     +E +KE  K+ ++  K    L  
Sbjct: 690 KEE-KKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSE 748

Query: 195 PLVPDLEKPSL 205
              P   KP +
Sbjct: 749 AKKPAALKPKV 759


>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
          Length = 495

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 40/149 (26%), Positives = 73/149 (48%), Gaps = 9/149 (6%)

Query: 38  RSGVEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKE 97
           R  +E +R   +Y EE     A I  +K      +KL K ++ K     E++  +K+L  
Sbjct: 313 REDLEQVRQ-ELYQEE----QAEIYKSKLKEEAEKKLRKQKEMKQDF--EEQMALKELVL 365

Query: 98  IAFPKAEE--LKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQ 155
            A  + EE   K  L K    +  E    +K+  ++L    A+++ +E+ +Q+    KQ+
Sbjct: 366 QAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLIEERRQQFLADKQR 425

Query: 156 QLEQEQFHAFEEMIRNQELEKERLKIVQE 184
           +LE+ Q     +   N  +E+ERLK+++E
Sbjct: 426 ELEEWQLQQRRQGFINAIIEEERLKLLKE 454



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 34/130 (26%), Positives = 70/130 (53%), Gaps = 17/130 (13%)

Query: 72  EKLPKHRDYKSAVIPEK---KDTVKKL-KEIAFPKAEEL-KAELLKRYTKEYTE----YN 122
           E+  K ++    ++ EK    + V+K+ +E    K ++L K   ++RY +E+ +    + 
Sbjct: 197 EQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWR 256

Query: 123 EEKKKEAEELARNMA----IQQELEKEKQRVAQQKQQ---QLEQEQFHAFEEMIRNQE-L 174
           ++K++E EE  R +     +QQ+ E+++    Q+ ++   QL+       EEM+R +E L
Sbjct: 257 KKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDL 316

Query: 175 EKERLKIVQE 184
           E+ R ++ QE
Sbjct: 317 EQVRQELYQE 326



 Score = 35.4 bits (80), Expect = 0.099
 Identities = 27/104 (25%), Positives = 55/104 (52%), Gaps = 11/104 (10%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           +K +  K+LKE+   + E+L  EL K    ++    +EK +  +++  N    +ELEK+ 
Sbjct: 74  QKAEENKRLKELQLKQEEKLAMELAK---LKHESLKDEKMR--QQVRENSIELRELEKKL 128

Query: 147 QRVAQQKQQ--QLEQEQFHAFEEMIRNQELEK----ERLKIVQE 184
           +     K++  Q+ ++    +E+M R+ E+ K    E  +I++E
Sbjct: 129 KAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKE 172



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 32/125 (25%), Positives = 61/125 (48%), Gaps = 15/125 (12%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           E++ +  +    ++ E K  +K+ +  A  K  + KA+      K+  E  E+KK+EA E
Sbjct: 150 EQMKRDAEIAKTMMEEHKRIIKE-ENAAEDKRNKAKAQYYLDLEKQLEEQ-EKKKQEAYE 207

Query: 132 --LARNMAIQQELEKEKQRVAQQKQQQLEQ--------EQFHAFEEMIR---NQELEKER 178
             L   + I + + K  +    +KQQ+LE+        E+F   + + R    +E+E+E 
Sbjct: 208 QLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEEN 267

Query: 179 LKIVQ 183
            KI++
Sbjct: 268 RKIIE 272


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 23/112 (20%), Positives = 65/112 (58%), Gaps = 10/112 (8%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEEL----------ARNM 136
           EK++ +++L+E+ + K E+++    K + +E     EEK++E E++          A+  
Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419

Query: 137 AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188
             ++++ ++++++ +Q+++   QE+    +E IR +E  +E+ ++ ++  K+
Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 22/87 (25%), Positives = 49/87 (56%), Gaps = 3/87 (3%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           EK++ +++ +E+ + K E+++      + KE      E+K   +E  R    Q+E  +E+
Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE---QEEKRQEE 402

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE 173
           +++ +Q+++Q ++ +    EE IR QE
Sbjct: 403 EKIREQEKRQEQEAKMWRQEEKIREQE 429



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 24/109 (22%), Positives = 62/109 (56%), Gaps = 8/109 (7%)

Query: 88  KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK-KEAEELARNM-----AIQQE 141
           +++ ++K +E  + + E++  +  K   +E   + +E+K +E EE  R         ++ 
Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545

Query: 142 LEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE--LEKERLKIVQEFGKV 188
           ++++++++ +Q+++  EQE+    EE IR QE  + +++ KI ++  K+
Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 33/130 (25%), Positives = 64/130 (49%), Gaps = 12/130 (9%)

Query: 71  IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKA-ELLKRYTKEYTEYNEEKK-KE 128
           +E++   ++ K   + EK    +K++E    + EE K  E  KR  +E   + +E+K +E
Sbjct: 368 LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427

Query: 129 AEELARNMAI----------QQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
            EE  R              +QE  +E+++  +Q++   ++E+    EE+ R +E   E+
Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487

Query: 179 LKIVQEFGKV 188
            KI ++  KV
Sbjct: 488 EKIRKQEEKV 497



 Score = 35.4 bits (80), Expect = 0.099
 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 19/158 (12%)

Query: 43  IIRMASIYSEEGNIEHAF---ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIA 99
           I R+   +   G +E A        K    +IE+L K RD  S  +     T ++LKE  
Sbjct: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223

Query: 100 FPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE-------KEKQRVAQQ 152
               E+L+   L    K   + N ++ K   E A+ +  QQ+L+       KE Q V+ +
Sbjct: 224 AKLQEKLQ---LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280

Query: 153 KQQQLEQEQF------HAFEEMIRNQELEKERLKIVQE 184
            Q Q+E+ +          E+M R +E  +E  + +QE
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318



 Score = 35.4 bits (80), Expect = 0.099
 Identities = 19/51 (37%), Positives = 32/51 (62%), Gaps = 4/51 (7%)

Query: 123 EEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173
           EEK++E EE+ R    Q+E  +E++ + +QK++  EQE+    EE +  QE
Sbjct: 455 EEKRQEQEEMWR----QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE 501



 Score = 35.0 bits (79), Expect = 0.13
 Identities = 22/90 (24%), Positives = 50/90 (55%), Gaps = 10/90 (11%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEK 144
           I E+++ +++ +E+   + E++  +  K   +E     EEK +E EE         ++ +
Sbjct: 532 IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE---------KIRE 582

Query: 145 EKQRVAQQKQQQLEQEQ-FHAFEEMIRNQE 173
           +K+++ +Q+++  EQE+     EEM++ QE
Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQE 612



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 5/63 (7%)

Query: 112 KRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-FHAFEEMIR 170
           KR  +E     EEK +E EE+ R    Q+E   E++++ +Q+++   QE+  H  EE IR
Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWR----QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR 512

Query: 171 NQE 173
            QE
Sbjct: 513 EQE 515



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 21/94 (22%), Positives = 49/94 (52%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEK 144
           I E+++ +++ +E    + E+++ +   R  +E     EEK +E +E  R    +   ++
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598

Query: 145 EKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
           EK R  ++  Q+ E++ +   E+M   +E  +E+
Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 23/103 (22%), Positives = 58/103 (56%), Gaps = 6/103 (5%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145
           ++++ +++ +E    + E+++ +  K R  +E     EEK +E EE+ +    ++  E+E
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE-EKMWEQE 619

Query: 146 KQRVAQQKQQQLEQEQFHAFEEMIRNQEL----EKERLKIVQE 184
           ++   Q+++ Q ++E+    EE +  QE+    ++E+++  QE
Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 20/87 (22%), Positives = 51/87 (58%), Gaps = 4/87 (4%)

Query: 88  KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147
           +++ +++ +EI   K +  + E +++  +E     EEK  + EE  R    ++++ ++++
Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEKIRKQ-EEKVWRQEEKMHDQEEKIREQ--EEKMWRQEE 523

Query: 148 RVAQQKQQQLEQEQ-FHAFEEMIRNQE 173
           ++ +Q+++  EQE+     EEM++ QE
Sbjct: 524 KIREQEEKIREQEEKIREQEEMMQEQE 550



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 18/87 (20%), Positives = 49/87 (56%), Gaps = 3/87 (3%)

Query: 88  KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147
           +++ +++ +E    + E+++ +      +E     +E+K + +E  R    ++++ ++++
Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ--EEKIREQEE 578

Query: 148 RVAQQKQQQLEQEQ-FHAFEEMIRNQE 173
           ++ +QK++  EQE+     EE IR QE
Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQE 605



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 21/89 (23%), Positives = 44/89 (49%), Gaps = 6/89 (6%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEK 144
           I E+K+ +++ +E  + + E+++ +      +E  +  EEK  E EE       + + ++
Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQ------EEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633

Query: 145 EKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173
           EK R  ++K  + E       E+M  +QE
Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 28/131 (21%), Positives = 68/131 (51%), Gaps = 13/131 (9%)

Query: 67  ITLFIEKLPKHRDYKSAVIPEKKDTV------KKLKEIAFP-KAEELKAELLKRYTKEYT 119
           I L +++L +  +    ++P+++         K+L+ ++   +A+  + EL  R  ++  
Sbjct: 240 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 299

Query: 120 EY---NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQEL-- 174
           E     EEK +E EE  +    +   ++EK R  ++K ++ E+  +   E+M R +E+  
Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359

Query: 175 -EKERLKIVQE 184
            ++E+++ ++E
Sbjct: 360 EKEEKMRRLEE 370



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 9/75 (12%)

Query: 116 KEYTEYNEEKKKEAEELARN----MAIQQEL--EKEKQRVAQQKQQQLEQEQFHAFEEMI 169
           +E  +  EEK +E EE  R     M  Q+E+  EKE++   Q++    ++E+    EEM+
Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372

Query: 170 RNQELEKERLKIVQE 184
             +E   E+++ ++E
Sbjct: 373 WEKE---EKIRELEE 384


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 32/127 (25%), Positives = 68/127 (53%), Gaps = 8/127 (6%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
           EKL K  D K  ++ EK+ + ++++E    K  E + EL K   +E  +  E+ ++  +E
Sbjct: 483 EKL-KRLDEKLGIL-EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE 540

Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQ------ELEKERLKIVQEF 185
             + +  +QE ++E ++  +Q++++  + Q    +E+ + +      ELEKER K+ ++ 
Sbjct: 541 KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600

Query: 186 GKVDPGL 192
              +P L
Sbjct: 601 EPREPNL 607



 Score = 39.3 bits (90), Expect = 0.007
 Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 6/110 (5%)

Query: 76  KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARN 135
           K R+ +  +  E++   +K +E    + +E + EL K   K+     E K+++ +EL R 
Sbjct: 511 KEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER- 569

Query: 136 MAIQQELEKEKQRV-AQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
              Q+E EKE Q++  Q+K+ +LE+E+    EE I  +E   E +   QE
Sbjct: 570 ---QKEKEKELQKMKEQEKECELEKER-EKLEEKIEPREPNLEPMVEKQE 615



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 29/113 (25%), Positives = 58/113 (51%), Gaps = 7/113 (6%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELK----AELLKRYTKEYTEYNEEKKK 127
           +++ K R  + + I    +  +K +E    + EE +    AE LKR  ++      EK+ 
Sbjct: 442 DEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIL--EKQP 499

Query: 128 EAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
             EE+ R    ++E E+EK+   +Q+Q++ ++ +     +  + +ELEKE+ K
Sbjct: 500 SPEEI-REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEK 551



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 7/98 (7%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           EK+   +K KE+   K +E + + +K   KE     E +K E +   R   ++  +EK  
Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK-- 613

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
               Q+ +    +E+   F     N+  EKE   +V E
Sbjct: 614 ----QESENSCNKEEEPVFTRQDSNRS-EKEATPVVHE 646


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 23/79 (29%), Positives = 47/79 (59%), Gaps = 2/79 (2%)

Query: 104 EELKAELLKRYTKEYTEY--NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161
           EE + +LLKR  ++  E    E++ K  +E  R+  +++E E+ +QR+ ++++++LEQ  
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602

Query: 162 FHAFEEMIRNQELEKERLK 180
                E +  +E  ++RLK
Sbjct: 603 KREEVERLEQEERREQRLK 621



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 23/97 (23%), Positives = 55/97 (56%), Gaps = 4/97 (4%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE----YNEEKKKEAEELARNMAIQQEL 142
           E++D +K+ +E    + E  K +L +   +E  E      EE+++E +E       +++ 
Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512

Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERL 179
           E+ +QR+ +Q++++  Q++  + +++ R QE  +E+L
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 23/92 (25%), Positives = 55/92 (59%), Gaps = 3/92 (3%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           E+++   KL+E    + +E + + L+R  +E  E   ++++E E L + +  +Q+L +E+
Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
           +   ++++Q L++E+    E+  R Q L++E+
Sbjct: 543 E---ERREQLLKREEEKRLEQERREQRLKREQ 571



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 26/109 (23%), Positives = 58/109 (53%), Gaps = 8/109 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLK--EIAFPKAEELKAELLKRYTKEYTEYNEEKKKEA 129
           EKL +    +   + E+++ ++KL+  E+   + EE + +   R  ++     EE+++E 
Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317

Query: 130 EELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
           +E  R    ++E ++E+      ++QQL +EQ    E+ +R ++ E+ R
Sbjct: 318 QEERREQQERREQQEER------REQQLRREQEERREQQLRREQEEERR 360



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 22/76 (28%), Positives = 46/76 (60%), Gaps = 3/76 (3%)

Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQE-QF 162
           EE + + L+R  +E  E  ++ ++E EE  R   +++E E+E++    +++QQL +E Q 
Sbjct: 332 EERREQQLRREQEERRE--QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389

Query: 163 HAFEEMIRNQELEKER 178
              +++ R Q+L +E+
Sbjct: 390 RREQQLRREQQLRREQ 405



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 18/122 (14%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKK-EAE 130
           EK  + R+ +  V  E+++   + +E    K EE   E   +  +E  E  E+ +K E +
Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284

Query: 131 ELARNMAIQQELEKEKQRVA--------------QQKQQQLEQEQFHAFEEMIRNQELEK 176
           EL R    +QE E+++QR+               +Q++++ EQ++    +E  R Q+L +
Sbjct: 285 ELRRE---RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341

Query: 177 ER 178
           E+
Sbjct: 342 EQ 343



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 18/92 (19%), Positives = 50/92 (54%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           E+++  ++ +E    + +E + E   R  +E     ++ ++E EE  R   +++E +  +
Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
           ++  +++QQ   ++Q    +++ R Q+L +E+
Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQ 417



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 2/100 (2%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQEL-EKE 145
           E+ +   K +E+   + EE + + LKR   E     +  K E +E  R   +++E  E+ 
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655

Query: 146 KQRVAQQKQQQ-LEQEQFHAFEEMIRNQELEKERLKIVQE 184
           +QR+ ++++++ LEQ      EE  R QEL +E  +  +E
Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695



 Score = 38.1 bits (87), Expect = 0.015
 Identities = 22/114 (19%), Positives = 62/114 (54%), Gaps = 12/114 (10%)

Query: 76   KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEK---------K 126
            + R  +     E+++  ++ +++   + E+ + + L+R  +E  E  +E+         K
Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160

Query: 127  KEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
            +  +EL R    ++EL++E++++ +++Q++  QE+   + E    +EL++++ K
Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE---EEELQRQKRK 1211



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFH 163
           EE K      Y K   +  E+ +KE + L       Q  E+EK+R  +Q++Q  E+EQ  
Sbjct: 880 EERKRRRHTLYAKPALQ--EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937

Query: 164 AFEEMIRNQELEKER 178
             EE +  +E EK R
Sbjct: 938 QEEEQLLREEREKRR 952



 Score = 37.7 bits (86), Expect = 0.020
 Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 5/100 (5%)

Query: 84   VIPEKKDTVKKLK-EIAFPKAEELKAE----LLKRYTKEYTEYNEEKKKEAEELARNMAI 138
            ++ E+++T ++ + E  + K EEL+ E    L +   K   +  E + +E EEL +    
Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122

Query: 139  QQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
                E+EK+R  + ++Q  E+E+    EE +  +E EK R
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 18/89 (20%), Positives = 49/89 (55%)

Query: 71  IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
           +E+L +    +  +  E+ +  ++ + +   + EE + + L+R  +E  E   ++++E E
Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666

Query: 131 ELARNMAIQQELEKEKQRVAQQKQQQLEQ 159
            L + +  + E E+ +Q +A+++Q+Q  +
Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARE 695



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 29/112 (25%), Positives = 56/112 (50%), Gaps = 5/112 (4%)

Query: 71  IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE--YNEEKKKE 128
           +E+  K R +     P  ++ ++K +++   + EEL+ E  ++  ++  E  Y EE++ +
Sbjct: 878 LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937

Query: 129 AEE---LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKE 177
            EE   L      ++  E+E+Q    +K QQ E++      E  R QE EK+
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989



 Score = 37.0 bits (84), Expect = 0.034
 Identities = 27/93 (29%), Positives = 54/93 (58%), Gaps = 14/93 (15%)

Query: 96  KEIAFPKAEELKAELLKRYTKEYTEYNEEKKK--------EAEELARNMAIQQELEKEKQ 147
           +E    + +E + + LKR  +E TE +E++++        E E   R + +++E  +E+Q
Sbjct: 443 REQRLKREQEERRDWLKR--EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500

Query: 148 RVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
              ++++QQL +EQ    E+ ++ QE E+ERL+
Sbjct: 501 ---ERREQQLRREQEERREQRLKRQE-EEERLQ 529



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 16/86 (18%), Positives = 49/86 (56%)

Query: 93  KKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQ 152
           +K +E    + EE + +  +R  +E     + ++++ E   + +  +QE E+ +Q++ ++
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367

Query: 153 KQQQLEQEQFHAFEEMIRNQELEKER 178
           ++++  ++Q    +++ R Q+L +E+
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQ 393



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 4/94 (4%)

Query: 87   EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
            E++   +K K++   + + L  E  KR  +E     E+K +E EEL +        E+EK
Sbjct: 955  ERERQYRKDKKLQQKEEQLLGEEPEKRRRQE----REKKYREEEELQQEEEQLLREEREK 1010

Query: 147  QRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
            +R  + ++Q  ++++    EE +  +E EK RL+
Sbjct: 1011 RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 25/98 (25%), Positives = 54/98 (55%), Gaps = 4/98 (4%)

Query: 87   EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEY---NEEKKKEAEELARNMAIQQELE 143
            E++   ++ +E+   + + L+ E  KR  +E+       +E ++E E+L R    ++ L+
Sbjct: 985  EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044

Query: 144  KEKQRVAQQKQQQLEQEQFHAFE-EMIRNQELEKERLK 180
            + +++  ++++ Q E+EQ    E E  R QELE++  K
Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 5/86 (5%)

Query: 100  FPKAEELKAELLKRYTKEYTEYNEEK---KKEAEELARNMAIQQELEKEKQRVAQQKQQQ 156
            FP+ E+L+ E  K   +   +  EEK   ++E EE  R     ++  +E+Q + ++++Q 
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352

Query: 157  L-EQEQFHAF-EEMIRNQELEKERLK 180
            L  QE+   F EE +R+QE  ++ L+
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLE 1378



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 10/125 (8%)

Query: 72   EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAEL-------LKRYTKEYTEYNEE 124
            E+  + ++ +   + E++   ++  E  F + E+L+ E         +RY K   E    
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756

Query: 125  KKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAF--EEMIRNQELEKERLKIV 182
             ++E ++L R    ++  E+E+ R  +++QQ   QE    F  EE +R QE E+++L+  
Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR-QEREEQQLRPQ 1815

Query: 183  QEFGK 187
            Q  GK
Sbjct: 1816 QRDGK 1820



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 17/86 (19%), Positives = 50/86 (58%), Gaps = 2/86 (2%)

Query: 93  KKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQ 152
           ++ +++   + EE + + L+R  +E  E  E++ +  ++L R   +++E +  +++  ++
Sbjct: 346 RREQQLRREQEEERREQQLRREQEE--ERREQQLRREQQLRREQQLRREQQLRREQQLRR 403

Query: 153 KQQQLEQEQFHAFEEMIRNQELEKER 178
           +QQ   ++Q    +++ R Q+L +E+
Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQ 429



 Score = 35.8 bits (81), Expect = 0.076
 Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 7/127 (5%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIA----FPKAEELKAELLKRYTKEYTEYNEEKKK 127
           E+L K  + K      ++  +K+ +E        + EE + + LKR  +E  E    K++
Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE-QRLKRE 605

Query: 128 EAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRN--QELEKERLKIVQEF 185
           E E L +    +Q L++E+    +++Q    +EQ    ++ +R   QE  ++RLK  +E 
Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665

Query: 186 GKVDPGL 192
            +++  L
Sbjct: 666 ERLEQRL 672



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 6/88 (6%)

Query: 96   KEIAFPKAEELKAE---LL--KRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVA 150
            +E  + + EEL+ E   LL  +R T+   E   + +KE EEL +        E EK+R  
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE-EELQQEEEQLLREEPEKRRRQ 1104

Query: 151  QQKQQQLEQEQFHAFEEMIRNQELEKER 178
            ++++Q  E+E+    EE +  +E EK R
Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRR 1132



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 2/90 (2%)

Query: 88   KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147
            KKD +++ +E      EE +   L+   ++Y E  E +++E + L      ++  E E+Q
Sbjct: 1022 KKDELQQEEEQLL--REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079

Query: 148  RVAQQKQQQLEQEQFHAFEEMIRNQELEKE 177
               +++ QQ E++      E  R QE E++
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQ 1109



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 19/77 (24%), Positives = 40/77 (51%)

Query: 102 KAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161
           +  +L+AE  ++  + +    EEK++   +        Q LE+E+Q   +++ QQL++E+
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853

Query: 162 FHAFEEMIRNQELEKER 178
               E+  R +  E+ R
Sbjct: 854 DGLQEDQERRRSQEQRR 870



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 20/78 (25%), Positives = 46/78 (58%), Gaps = 5/78 (6%)

Query: 105  ELKAELLKRYTKEYTEYNEEKK-KEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-- 161
            E + +L ++  ++   ++ ++K +E E+L +    QQ   +E+ R  ++++QQL +++  
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706

Query: 162  --FHAFEEMIRNQELEKE 177
              F   E+ +R QELE++
Sbjct: 1707 RKFLQEEQQLRRQELERK 1724



 Score = 33.9 bits (76), Expect = 0.29
 Identities = 22/79 (27%), Positives = 44/79 (55%), Gaps = 7/79 (8%)

Query: 113  RYTKEYTEYNEEKKKEAEELARN------MAIQQELEKEKQRVAQQKQQQLEQEQFHAF- 165
            R+ +E  +  E++++  +E  R        A Q++  +E+Q + Q+++Q+  QE+     
Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881

Query: 166  EEMIRNQELEKERLKIVQE 184
            EE IR Q+ E++R + V E
Sbjct: 1882 EEHIRRQQKEEQRHRQVGE 1900



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 31/125 (24%), Positives = 63/125 (50%), Gaps = 21/125 (16%)

Query: 72   EKLPKHRDYKSA----VIPEKKDTVKKLKEI--AFPKAEEL----------KAELLKRYT 115
            +K  K RD KS     ++ E+++  ++ +E    F + E+L          + E  +++ 
Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363

Query: 116  KEYTEYNEEKKKEAEELARNMAIQQE---LEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQ 172
            +E   + E+ +K  EE  R    ++E   L++E+Q   Q+++QQL Q++   F E    Q
Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE--EEQ 1421

Query: 173  ELEKE 177
            +L ++
Sbjct: 1422 QLSRQ 1426



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 20/85 (23%), Positives = 45/85 (52%), Gaps = 4/85 (4%)

Query: 104  EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-- 161
            +E   + L+   +   +  E K  + E+  R    +Q+L +++ R  ++++QQL +++  
Sbjct: 1370 QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429

Query: 162  --FHAFEEMIRNQELEKERLKIVQE 184
              F   E+ +R QE E++ L+  Q+
Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQ 1454



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 1/88 (1%)

Query: 93   KKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQ 152
            K LKE    + +E + +L +   +++ E  ++  ++  +       QQ   +E++R   +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450

Query: 153  KQQQLEQEQFHAF-EEMIRNQELEKERL 179
            ++QQL QE+   F EE    QE E+++L
Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQL 1478



 Score = 32.3 bits (72), Expect = 0.84
 Identities = 28/118 (23%), Positives = 62/118 (52%), Gaps = 5/118 (4%)

Query: 72   EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEE---KKKE 128
            ++L + RD K     ++    ++ ++    + +  + E  +++ +E  +  +E   K +E
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1465

Query: 129  AEELARNMAIQQELEKEKQRVAQQKQQQL-EQEQFHAF-EEMIRNQELEKERLKIVQE 184
             E+L +    QQ   +E+ R   +++QQL  QE+   F E+ +R+QE E++ L+  Q+
Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQ 1523



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 24/97 (24%), Positives = 51/97 (52%), Gaps = 16/97 (16%)

Query: 100 FPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKE---KQRVAQQKQQQ 156
           FP  E+L+   L    ++  E  +++++E ++       Q+E EKE   ++ V ++++++
Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEKEWRKRETVLRKEEEK 259

Query: 157 LEQE------QFHAFEEMIR---NQELEKERLKIVQE 184
           L++E      +    EE +R    QEL +ER +  Q+
Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 20/85 (23%), Positives = 48/85 (56%), Gaps = 4/85 (4%)

Query: 104 EELKAELLKRYTKEYTEY--NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161
           +E + + LKR  +E  ++   EE+ +  E+  R   ++++ E+E++    + +++  +EQ
Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499

Query: 162 FHAFEEMIRNQELEK--ERLKIVQE 184
               E+ +R ++ E+  +RLK  +E
Sbjct: 500 QERREQQLRREQEERREQRLKRQEE 524



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 4/86 (4%)

Query: 97   EIAFPKAEELKAE----LLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQ 152
            E  + K +EL+ E    L +   K   +  E + +E EEL +        E+E +R  + 
Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076

Query: 153  KQQQLEQEQFHAFEEMIRNQELEKER 178
            ++Q  ++E+    EE +  +E EK R
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRR 1102



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 23/106 (21%), Positives = 53/106 (50%), Gaps = 19/106 (17%)

Query: 87   EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQ------ 140
            E++   ++ ++  F + E+L+ E  ++  +  ++ ++ K +E E+L +    QQ      
Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLR--SQESDRKFREEEQLRQEREEQQLRPQQR 1817

Query: 141  -----------ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELE 175
                       +LE+++QR+ Q++ +Q   E+  A +E  R +E E
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 22/101 (21%), Positives = 55/101 (54%), Gaps = 6/101 (5%)

Query: 88  KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAI--QQELEKE 145
           +++  ++ +E    + ++L+ E  ++  +E     E++ +  ++L R   +  +Q+L +E
Sbjct: 365 RREQEEERREQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422

Query: 146 KQRVAQQKQQQLEQ--EQFHAFEEMIRNQELEKERLKIVQE 184
           +Q   +Q++++ EQ  EQ    + + R QE  ++ LK  +E
Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEE 463



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 24/98 (24%), Positives = 50/98 (51%), Gaps = 4/98 (4%)

Query: 87   EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYT-EYNEEKK---KEAEELARNMAIQQEL 142
            E++   ++ +++   + + L+ E  KR  +E   +Y ++KK   KE + L      ++  
Sbjct: 925  EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984

Query: 143  EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
            E+EK+   +++ QQ E++      E  R QE E++  K
Sbjct: 985  EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 4/79 (5%)

Query: 104  EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-- 161
            +E + + L R  ++     EE++   +E  R    Q+   +E +R   +++QQL ++Q  
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530

Query: 162  --FHAFEEMIRNQELEKER 178
              F   E+ +R QE  ++R
Sbjct: 1531 RKFLQEEQQLRRQERGQQR 1549



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 8/75 (10%)

Query: 104  EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFH 163
            +E + + L R  ++     EE+K   +E  R       +E E+Q   Q+ QQQL QE+  
Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKF-----MEDEQQLRRQEGQQQLRQERDR 1619

Query: 164  AFEEMIRNQELEKER 178
             F E   +++L +ER
Sbjct: 1620 KFRE---DEQLLQER 1631



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 23/102 (22%), Positives = 53/102 (51%), Gaps = 5/102 (4%)

Query: 87   EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
            +++D   +  E    + EE +    +R  K   E  + +++E E+  R+    ++  +E+
Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR-DRKFREEE 1673

Query: 147  QRVAQQKQQQLEQEQ----FHAFEEMIRNQELEKERLKIVQE 184
            Q + + ++QQL +++    F   E+ +R QE E++ L+  Q+
Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQ 1715



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 18/117 (15%)

Query: 72   EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
            E+L +  +      PEK+   ++ ++    + EEL+ E      ++      EK++  +E
Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCR--EEEELQQE-----EEQLLREEREKRRR-QE 1135

Query: 132  LARNMAIQQEL----------EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
            L R    ++E+          E EK+R  + ++Q  E+E+    EE +  +E EK R
Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR 1192



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 12/56 (21%), Positives = 37/56 (66%), Gaps = 5/56 (8%)

Query: 123  EEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
            E++++  ++  R+   +++LE+E+Q+ A+++ ++ ++E+     +++R +  EK R
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK-----QLLREEREEKRR 1330



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 26/119 (21%), Positives = 63/119 (52%), Gaps = 14/119 (11%)

Query: 70   FIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEA 129
            F+E+ P+ R        E++  ++  ++  F + E+L  E  ++  +   +  + K +E 
Sbjct: 1645 FLEEEPQLRRQ------EREQQLRHDRDRKFREEEQLLQEGEEQQLRR--QERDRKFREE 1696

Query: 130  EELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188
            E+  R    +++  +E+Q++ +Q+ ++  +E     EE +R QE E+E+L+  + + K+
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFRE-----EEQLR-QETEQEQLRRQERYRKI 1749



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 22/99 (22%), Positives = 53/99 (53%), Gaps = 12/99 (12%)

Query: 96  KEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK---QRVAQQ 152
           +E    + ++L+ E  ++  +E     E++ +  ++L R   +++E E+E+   +   ++
Sbjct: 385 REQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442

Query: 153 KQQQLEQEQFHAFEEMIRNQELE-------KERLKIVQE 184
           ++Q+L++EQ    + + R +E E       K++LK  QE
Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 3/84 (3%)

Query: 104  EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQE--- 160
            EE +    +R  K   E  + +++E  +  R    ++  E+E+ R  +++QQ   QE   
Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR 1579

Query: 161  QFHAFEEMIRNQELEKERLKIVQE 184
            +F   E+ +R QE E++ ++  Q+
Sbjct: 1580 KFRLEEQKVRRQEQERKFMEDEQQ 1603



 Score = 28.9 bits (63), Expect = 9.2
 Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 8/102 (7%)

Query: 76   KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARN 135
            + R Y+     +KK   K+ + +     +  + E  K+Y +E     EE++   EE  + 
Sbjct: 956  RERQYRK----DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011

Query: 136  MAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKE 177
               + E +  K+   QQ+++QL +E+     E  R QE E++
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREE----REKRRLQERERQ 1049



 Score = 28.9 bits (63), Expect = 9.2
 Identities = 25/106 (23%), Positives = 56/106 (52%), Gaps = 5/106 (4%)

Query: 72   EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEE---LKAELLKRYTKEYTEYNEEK-KK 127
            E+L + R+ +  + P+++D   + +E      E+   L+ E  ++Y  E     +EK ++
Sbjct: 1801 EQLRQERE-EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR 1859

Query: 128  EAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173
            E +EL +    ++  E+E++   +  ++Q ++EQ H     I++QE
Sbjct: 1860 EEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905


>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
           sapiens]
          Length = 482

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 30/117 (25%), Positives = 62/117 (52%), Gaps = 9/117 (7%)

Query: 70  FIEKLPKHRDYKSAVIPEKK----DTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEK 125
           F EK P H+ Y++A+  EK+      + +L++    + EE +   ++    E  +  E +
Sbjct: 9   FPEK-PSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERE 67

Query: 126 KKEAEE--LARNMAIQQE--LEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
           ++   E  L R    Q+E  ++KEK+  A+++Q++ E++    +EE  R +  E+E+
Sbjct: 68  RQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124



 Score = 32.7 bits (73), Expect = 0.64
 Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 6/67 (8%)

Query: 92  VKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQ 151
           +KK KE A  K +E +   LK       ++ E+++KE EE  +    ++E E+  Q++  
Sbjct: 88  IKKEKEEAAKKRQEEQERKLKE------QWEEQQRKEREEEEQKRQEKKEKEEALQKMLD 141

Query: 152 QKQQQLE 158
           Q + +LE
Sbjct: 142 QAENELE 148


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 29/102 (28%), Positives = 59/102 (57%), Gaps = 10/102 (9%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE--- 143
           EK++ +++ +E+ + K E+++    K + +E     EEK++E EE  R    +QE E   
Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKM 479

Query: 144 -KEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
            ++++++ +Q+++  EQE     E+M R +E   E+ KI +E
Sbjct: 480 WRQEEKIREQEEKIREQE-----EKMWRQEEKIHEQEKIREE 516



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 22/87 (25%), Positives = 50/87 (57%), Gaps = 3/87 (3%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           EK++ +++ +E+ + K E+++ +    + KE      E+K   +E  R    Q+E  +E+
Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE---QEEKRQEE 463

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE 173
           +++ +Q+++Q ++ +    EE IR QE
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQE 490



 Score = 38.9 bits (89), Expect = 0.009
 Identities = 34/123 (27%), Positives = 65/123 (52%), Gaps = 6/123 (4%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKA-ELLKRYTKEYTEYNEEKK-KEA 129
           E++   ++ K   + EK    +K++E    + EE K  E  KR  +E   + +E+K +E 
Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489

Query: 130 EELARNMAIQQELEKEK---QRVAQQKQQQLEQEQFHAFEEMIRNQ-ELEKERLKIVQEF 185
           EE  R    +   ++EK   Q   ++++++ EQE+    EE IR Q E+ +++ KI ++ 
Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549

Query: 186 GKV 188
            K+
Sbjct: 550 EKI 552



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 25/95 (26%), Positives = 54/95 (56%), Gaps = 9/95 (9%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKA-----ELLKRYTKEYTEYNEEKKKEAEELARNMAIQ 139
           I E+++ +++ +E  + + E++       E  KR  +E     EEK +E EE+ R    +
Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ---K 542

Query: 140 QELEKEKQRVAQQKQQQLEQEQ-FHAFEEMIRNQE 173
           +++ ++++++ +Q+++   QE+  H  EE IR QE
Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577



 Score = 35.4 bits (80), Expect = 0.099
 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 19/158 (12%)

Query: 43  IIRMASIYSEEGNIEHAF---ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIA 99
           I R+   +   G +E A        K    +IE+L K RD  S  +     T ++LKE  
Sbjct: 225 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 284

Query: 100 FPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE-------KEKQRVAQQ 152
               E+L+   L    K   + N ++ K   E A+ +  QQ+L+       KE Q V+ +
Sbjct: 285 AKLQEKLQ---LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 341

Query: 153 KQQQLEQEQF------HAFEEMIRNQELEKERLKIVQE 184
            Q Q+E+ +          E+M R +E  +E  + +QE
Sbjct: 342 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 379



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 28/92 (30%), Positives = 54/92 (58%), Gaps = 6/92 (6%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQE-L 142
           I E+++ V + +E    + E+++ +  K R  +E T+  EEK  E EE    M  Q+E +
Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE---KMCEQEEKM 629

Query: 143 EKEKQRVAQQKQQQLEQE-QFHAFEEMIRNQE 173
           +++++++ +Q+++  EQE +    EE IR QE
Sbjct: 630 QEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661



 Score = 34.3 bits (77), Expect = 0.22
 Identities = 20/98 (20%), Positives = 58/98 (59%), Gaps = 13/98 (13%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           ++++ +++ +E  + + E+++ +      +E     EEK +E EE+ +    ++++ +++
Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQ------EEKIREQEEKIREQEEMTQEQ--EEKMGEQE 619

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
           +++ +Q+++  EQE     E+M R +E  +E+ K ++E
Sbjct: 620 EKMCEQEEKMQEQE-----EKMRRQEEKIREQEKKIRE 652



 Score = 32.7 bits (73), Expect = 0.64
 Identities = 21/95 (22%), Positives = 49/95 (51%), Gaps = 1/95 (1%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYT-EYNEEKKKEAEELARNMAIQQELE 143
           I E+++ +++ +E+   + E++  +  K   +E   +  EEK +  EE  R    +   +
Sbjct: 594 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ 653

Query: 144 KEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178
           +EK R  ++  Q+ E++ +   E+M   +E  +E+
Sbjct: 654 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 6/82 (7%)

Query: 113 RYTKEYTEYNEEKKKEAEEL----ARNMAIQQEL--EKEKQRVAQQKQQQLEQEQFHAFE 166
           R  +E     EEK +  EE+       M  Q+E+  EKE++   Q++    ++E+    E
Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444

Query: 167 EMIRNQELEKERLKIVQEFGKV 188
           E +  QE  +E+ +  QE  K+
Sbjct: 445 EKMHEQEKIREQEEKRQEEEKI 466



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 16/71 (22%), Positives = 41/71 (57%), Gaps = 1/71 (1%)

Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-F 162
           EE   E  ++  ++  +  E++KK  E+  +    ++ ++++++++ +Q+++  EQE+  
Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685

Query: 163 HAFEEMIRNQE 173
              EE +R QE
Sbjct: 686 QEQEEKMRRQE 696



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 17/90 (18%), Positives = 52/90 (57%), Gaps = 3/90 (3%)

Query: 88  KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK-KEAEELARNMAIQQELEKEK 146
           +++ + + KE    + E+++ +  K + +E   +++E+K +E EE       ++++ +++
Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ--EEKIREQE 591

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEK 176
           +++ +Q+++  EQE+    +E    ++ EK
Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEK 621



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 31/130 (23%), Positives = 64/130 (49%), Gaps = 12/130 (9%)

Query: 67  ITLFIEKLPKHRDYKSAVIPEKKDTV------KKLKEIAFP-KAEELKAELLKRYTKEYT 119
           I L +++L +  +    ++P+++         K+L+ ++   +A+  + EL  R  ++  
Sbjct: 301 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 360

Query: 120 EY---NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQEL-- 174
           E     EEK +E EE  +    +   ++EK R  ++K ++ E+  +   E+M R +E+  
Sbjct: 361 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420

Query: 175 EKERLKIVQE 184
           EKE     QE
Sbjct: 421 EKEEKMRRQE 430



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 21/87 (24%), Positives = 48/87 (55%), Gaps = 3/87 (3%)

Query: 88  KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147
           +++ +++ +EI   K +  + E   R  +E     EEK  + EE  R    ++++ ++++
Sbjct: 528 QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ--EEKVWRQEE 585

Query: 148 RVAQQKQQQLEQEQ-FHAFEEMIRNQE 173
           ++ +Q+++  EQE+     EEM + QE
Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQE 612



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 6/80 (7%)

Query: 109 ELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEM 168
           E ++   K+  E  EEK +E EE+ +    ++  E+E++   Q+++ Q ++E+    EE 
Sbjct: 641 EKIREQEKKIRE-QEEKIREQEEMMQEQE-EKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698

Query: 169 IRNQEL----EKERLKIVQE 184
           +  QE+    ++E+++  QE
Sbjct: 699 MWEQEVRLRQQEEKMQEHQE 718


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
           sapiens]
          Length = 1972

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 10/101 (9%)

Query: 88  KKDTVKKLKEIAFPKAEELKAEL-LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           K+D ++K KE       + KAE  LK   +++++  EEK    E+L     +  E E+ +
Sbjct: 857 KEDELQKTKE------RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910

Query: 147 QRVAQQKQQQ---LEQEQFHAFEEMIRNQELEKERLKIVQE 184
            R+A +KQ+    L + +    EE  R Q+L+ ER K+ Q+
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNE------EK 125
           ++L K ++ +     E K+  +K  ++   K   L  E L+  T+ Y E  E       K
Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEEK--NLLQEQLQAETELYAEAEEMRVRLAAK 916

Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181
           K+E EE+   M  + E E+++ +  Q +++++ Q+     EE +  +E  +++L++
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD-LEEQLEEEEAARQKLQL 971



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%)

Query: 71   IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
            +E     RD   A   E +   K L+       E+L A    R   +      EK++ AE
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL-----EKEELAE 1715

Query: 131  ELARNMAIQQELEKEKQRV---AQQKQQQLEQEQ--FHAFEEMIRNQELEKERL 179
            ELA +++ +  L+ EK+R+     Q +++LE+EQ    A  + +R    + E+L
Sbjct: 1716 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%)

Query: 72   EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
            E++ +    K A     K   KKLKEI       L+ E  ++  ++Y E  E+     ++
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEIL------LQVEDERKMAEQYKEQAEKGNARVKQ 1881

Query: 132  LARNMAIQQELEKEKQRV--AQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
            L R +   +E E+E QR+   ++K Q+   E   + E M R     K +L+
Sbjct: 1882 LKRQL---EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 117 EYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLE-----QEQFHAFEEMIRN 171
           + T   EE + + +EL +    QQ+ E E + + Q+  Q  E     QEQ  A  E+   
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905

Query: 172 QELEKERL 179
            E  + RL
Sbjct: 906 AEEMRVRL 913


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
           sapiens]
          Length = 1979

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 10/101 (9%)

Query: 88  KKDTVKKLKEIAFPKAEELKAEL-LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           K+D ++K KE       + KAE  LK   +++++  EEK    E+L     +  E E+ +
Sbjct: 864 KEDELQKTKE------RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917

Query: 147 QRVAQQKQQQ---LEQEQFHAFEEMIRNQELEKERLKIVQE 184
            R+A +KQ+    L + +    EE  R Q+L+ ER K+ Q+
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNE------EK 125
           ++L K ++ +     E K+  +K  ++   K   L  E L+  T+ Y E  E       K
Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEEK--NLLQEQLQAETELYAEAEEMRVRLAAK 923

Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181
           K+E EE+   M  + E E+++ +  Q +++++ Q+     EE +  +E  +++L++
Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD-LEEQLEEEEAARQKLQL 978



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%)

Query: 71   IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
            +E     RD   A   E +   K L+       E+L A    R   +      EK++ AE
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL-----EKEELAE 1722

Query: 131  ELARNMAIQQELEKEKQRV---AQQKQQQLEQEQ--FHAFEEMIRNQELEKERL 179
            ELA +++ +  L+ EK+R+     Q +++LE+EQ    A  + +R    + E+L
Sbjct: 1723 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1776



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%)

Query: 72   EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
            E++ +    K A     K   KKLKEI       L+ E  ++  ++Y E  E+     ++
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEIL------LQVEDERKMAEQYKEQAEKGNARVKQ 1888

Query: 132  LARNMAIQQELEKEKQRV--AQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
            L R +   +E E+E QR+   ++K Q+   E   + E M R     K +L+
Sbjct: 1889 LKRQL---EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 117 EYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLE-----QEQFHAFEEMIRN 171
           + T   EE + + +EL +    QQ+ E E + + Q+  Q  E     QEQ  A  E+   
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912

Query: 172 QELEKERL 179
            E  + RL
Sbjct: 913 AEEMRVRL 920


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
           sapiens]
          Length = 1945

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 10/101 (9%)

Query: 88  KKDTVKKLKEIAFPKAEELKAEL-LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           K+D ++K KE       + KAE  LK   +++++  EEK    E+L     +  E E+ +
Sbjct: 864 KEDELQKTKE------RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917

Query: 147 QRVAQQKQQQ---LEQEQFHAFEEMIRNQELEKERLKIVQE 184
            R+A +KQ+    L + +    EE  R Q+L+ ER K+ Q+
Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNE------EK 125
           ++L K ++ +     E K+  +K  ++   K   L  E L+  T+ Y E  E       K
Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEEK--NLLQEQLQAETELYAEAEEMRVRLAAK 923

Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181
           K+E EE+   M  + E E+++ +  Q +++++ Q+     EE +  +E  +++L++
Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD-LEEQLEEEEAARQKLQL 978



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%)

Query: 71   IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
            +E     RD   A   E +   K L+       E+L A    R   +      EK++ AE
Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL-----EKEELAE 1722

Query: 131  ELARNMAIQQELEKEKQRV---AQQKQQQLEQEQ--FHAFEEMIRNQELEKERL 179
            ELA +++ +  L+ EK+R+     Q +++LE+EQ    A  + +R    + E+L
Sbjct: 1723 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1776



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%)

Query: 72   EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
            E++ +    K A     K   KKLKEI       L+ E  ++  ++Y E  E+     ++
Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEIL------LQVEDERKMAEQYKEQAEKGNARVKQ 1888

Query: 132  LARNMAIQQELEKEKQRV--AQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
            L R +   +E E+E QR+   ++K Q+   E   + E M R     K +L+
Sbjct: 1889 LKRQL---EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 117 EYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLE-----QEQFHAFEEMIRN 171
           + T   EE + + +EL +    QQ+ E E + + Q+  Q  E     QEQ  A  E+   
Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912

Query: 172 QELEKERL 179
            E  + RL
Sbjct: 913 AEEMRVRL 920


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
           sapiens]
          Length = 1938

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 10/101 (9%)

Query: 88  KKDTVKKLKEIAFPKAEELKAEL-LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           K+D ++K KE       + KAE  LK   +++++  EEK    E+L     +  E E+ +
Sbjct: 857 KEDELQKTKE------RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910

Query: 147 QRVAQQKQQQ---LEQEQFHAFEEMIRNQELEKERLKIVQE 184
            R+A +KQ+    L + +    EE  R Q+L+ ER K+ Q+
Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951



 Score = 36.6 bits (83), Expect = 0.044
 Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNE------EK 125
           ++L K ++ +     E K+  +K  ++   K   L  E L+  T+ Y E  E       K
Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEEK--NLLQEQLQAETELYAEAEEMRVRLAAK 916

Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181
           K+E EE+   M  + E E+++ +  Q +++++ Q+     EE +  +E  +++L++
Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD-LEEQLEEEEAARQKLQL 971



 Score = 34.7 bits (78), Expect = 0.17
 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%)

Query: 71   IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130
            +E     RD   A   E +   K L+       E+L A    R   +      EK++ AE
Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL-----EKEELAE 1715

Query: 131  ELARNMAIQQELEKEKQRV---AQQKQQQLEQEQ--FHAFEEMIRNQELEKERL 179
            ELA +++ +  L+ EK+R+     Q +++LE+EQ    A  + +R    + E+L
Sbjct: 1716 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769



 Score = 33.1 bits (74), Expect = 0.49
 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%)

Query: 72   EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131
            E++ +    K A     K   KKLKEI       L+ E  ++  ++Y E  E+     ++
Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEIL------LQVEDERKMAEQYKEQAEKGNARVKQ 1881

Query: 132  LARNMAIQQELEKEKQRV--AQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
            L R +   +E E+E QR+   ++K Q+   E   + E M R     K +L+
Sbjct: 1882 LKRQL---EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%)

Query: 117 EYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLE-----QEQFHAFEEMIRN 171
           + T   EE + + +EL +    QQ+ E E + + Q+  Q  E     QEQ  A  E+   
Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905

Query: 172 QELEKERL 179
            E  + RL
Sbjct: 906 AEEMRVRL 913


>gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform
           b [Homo sapiens]
          Length = 1524

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 26/105 (24%), Positives = 60/105 (57%), Gaps = 5/105 (4%)

Query: 80  YKSAVIPEKKDTVKK--LKEIAFPKAE--ELKAELLKRYTKEYTEYNEEKKKEAEELARN 135
           Y+S    E+   +K+  +K +AF KA+    KA+ L+   KE  E  E+K++E +++   
Sbjct: 300 YRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKE-KEDKEKKREELKKIVEE 358

Query: 136 MAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
             ++++ EKE+ +V ++K+++  +E+   + E ++     +E ++
Sbjct: 359 ERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDME 403



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 15/55 (27%), Positives = 38/55 (69%), Gaps = 2/55 (3%)

Query: 109 ELLKRYTKEYTEYN-EEKKKEAEELARNMAIQQELE-KEKQRVAQQKQQQLEQEQ 161
           ++L++  +E+ E   E+ +KE EE A  +  ++E + KE+++  ++KQ++L++++
Sbjct: 607 DILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDE 661


>gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform
           a [Homo sapiens]
          Length = 1556

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 26/105 (24%), Positives = 60/105 (57%), Gaps = 5/105 (4%)

Query: 80  YKSAVIPEKKDTVKK--LKEIAFPKAE--ELKAELLKRYTKEYTEYNEEKKKEAEELARN 135
           Y+S    E+   +K+  +K +AF KA+    KA+ L+   KE  E  E+K++E +++   
Sbjct: 300 YRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKE-KEDKEKKREELKKIVEE 358

Query: 136 MAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180
             ++++ EKE+ +V ++K+++  +E+   + E ++     +E ++
Sbjct: 359 ERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDME 403



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 15/55 (27%), Positives = 38/55 (69%), Gaps = 2/55 (3%)

Query: 109 ELLKRYTKEYTEYN-EEKKKEAEELARNMAIQQELE-KEKQRVAQQKQQQLEQEQ 161
           ++L++  +E+ E   E+ +KE EE A  +  ++E + KE+++  ++KQ++L++++
Sbjct: 639 DILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDE 693


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 22/112 (19%), Positives = 64/112 (57%), Gaps = 10/112 (8%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEEL----------ARNM 136
           EK++ +++ +E+ + K E+++    K + +E     EEK++E E++          A+  
Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433

Query: 137 AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188
             ++++ ++++++ +Q+++   QE+    +E IR +E  +E+ ++ ++  K+
Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 22/87 (25%), Positives = 50/87 (57%), Gaps = 3/87 (3%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           EK++ +++ +E+ + K E+++ +    + KE      E+K   +E  R    Q+E  +E+
Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE---QEEKRQEE 416

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE 173
           +++ +Q+++Q ++ +    EE IR QE
Sbjct: 417 EKIREQEKRQEQEAKMWRQEEKIREQE 443



 Score = 37.4 bits (85), Expect = 0.026
 Identities = 23/88 (26%), Positives = 53/88 (60%), Gaps = 5/88 (5%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145
           E+++ ++K +E  + + E+++ +  K R  +E     EEK +E EE+ R    ++E   E
Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR----EEEKMHE 555

Query: 146 KQRVAQQKQQQLEQEQFHAFEEMIRNQE 173
           ++++ +++++Q ++++    EE IR QE
Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQE 583



 Score = 36.2 bits (82), Expect = 0.058
 Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 13/130 (10%)

Query: 72  EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKA-ELLKRYTKEYTEYNEEKK-KEA 129
           E++   ++ K   + EK    +K++E    + EE K  E  KR  +E   + +E+K +E 
Sbjct: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442

Query: 130 EELARN----MAIQQEL--EKEKQRVAQQKQQQLE----QEQFHAFEEMIRNQE-LEKER 178
           EE  R     M  Q+E   E+EK R  +++Q+Q E    +E+ H  EE+ R +E + ++ 
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502

Query: 179 LKIVQEFGKV 188
            KI ++  KV
Sbjct: 503 EKIRKQEEKV 512



 Score = 35.4 bits (80), Expect = 0.099
 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 19/158 (12%)

Query: 43  IIRMASIYSEEGNIEHAF---ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIA 99
           I R+   +   G +E A        K    +IE+L K RD  S  +     T ++LKE  
Sbjct: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223

Query: 100 FPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE-------KEKQRVAQQ 152
               E+L+   L    K   + N ++ K   E A+ +  QQ+L+       KE Q V+ +
Sbjct: 224 AKLQEKLQ---LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280

Query: 153 KQQQLEQEQF------HAFEEMIRNQELEKERLKIVQE 184
            Q Q+E+ +          E+M R +E  +E  + +QE
Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 20/101 (19%), Positives = 56/101 (55%), Gaps = 2/101 (1%)

Query: 88  KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147
           +++ + + +EI   K +  + E   R  +E     EEK +E EE  R    ++++ ++++
Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ--EEKMWRQEE 538

Query: 148 RVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188
           ++ +Q++   E+E+ H  E++   ++ +++  K+ ++  K+
Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 25/89 (28%), Positives = 47/89 (52%), Gaps = 3/89 (3%)

Query: 102 KAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161
           + EE   E  K + +E  +  E+K    EE  R    +   ++EK R  ++K+Q+ E++ 
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607

Query: 162 FHAFEEMIRNQE--LEKERLKIVQEFGKV 188
           +   EE IR QE  ++++  KI ++  K+
Sbjct: 608 WKQ-EEKIREQEEKIQEQEEKIREQEEKI 635



 Score = 33.5 bits (75), Expect = 0.38
 Identities = 23/101 (22%), Positives = 59/101 (58%), Gaps = 8/101 (7%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQELE 143
           I E+++  ++ +E  + + E+++ +  K +  +E     EEK +E EE+ +    ++++ 
Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ--EEKMG 650

Query: 144 KEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184
           ++++++ +Q+++  EQE     E M R +E  +E+ K ++E
Sbjct: 651 EQEEKMCEQEEKMQEQE-----ETMWRQEEKIREQEKKIRE 686



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 28/111 (25%), Positives = 56/111 (50%), Gaps = 7/111 (6%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEEL----ARNMAIQ 139
           I E ++ +++ +E    + E+++ +  K R  +E     EEK +  EE+       M  Q
Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368

Query: 140 QEL--EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188
           +E+  EKE++   Q++    ++E+    EE +  QE  +E+ +  QE  K+
Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 22/90 (24%), Positives = 50/90 (55%), Gaps = 6/90 (6%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145
           ++++ +++ +E    + E+++ +  K R  +E T+  EEK  E EE    M  Q+E  +E
Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE---KMCEQEEKMQE 665

Query: 146 KQRVAQQKQQQLEQEQ--FHAFEEMIRNQE 173
           ++    ++++++ +++      EE IR QE
Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQE 695



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 6/87 (6%)

Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNM-----AIQQELEKEKQRVAQQKQQQLE 158
           EE+  +  K + +E     +EK  E EE  R         ++++ ++++++ +Q+++   
Sbjct: 476 EEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR 535

Query: 159 QEQ-FHAFEEMIRNQELEKERLKIVQE 184
           QE+     EEM R +E   E+ KI +E
Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEE 562



 Score = 30.4 bits (67), Expect = 3.2
 Identities = 18/62 (29%), Positives = 37/62 (59%), Gaps = 3/62 (4%)

Query: 113 RYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQ-QLEQEQFHAFEEMIRN 171
           R  +E     EEK +E EE  +    ++++ K+++++ +Q+++ Q ++E+    EE IR 
Sbjct: 580 REQEEKVWRQEEKIREQEE--KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637

Query: 172 QE 173
           QE
Sbjct: 638 QE 639



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 22/98 (22%), Positives = 53/98 (54%), Gaps = 11/98 (11%)

Query: 85  IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK--------KEAEELARNM 136
           I E+++  ++ +E    + E++  +  K   +E T + +E+K        +E EE  R  
Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694

Query: 137 AIQQELEKEKQRVAQQKQQQLEQEQ-FHAFEEMIRNQE 173
             ++ ++++++++ +Q+++  EQE+     EE +R QE
Sbjct: 695 --EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 31/130 (23%), Positives = 64/130 (49%), Gaps = 12/130 (9%)

Query: 67  ITLFIEKLPKHRDYKSAVIPEKKDTV------KKLKEIAFP-KAEELKAELLKRYTKEYT 119
           I L +++L +  +    ++P+++         K+L+ ++   +A+  + EL  R  ++  
Sbjct: 240 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 299

Query: 120 EY---NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQEL-- 174
           E     EEK +E EE  +    +   ++EK R  ++K ++ E+  +   E+M R +E+  
Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359

Query: 175 EKERLKIVQE 184
           EKE     QE
Sbjct: 360 EKEEKMRRQE 369



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 17/88 (19%), Positives = 53/88 (60%), Gaps = 4/88 (4%)

Query: 88  KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK-KEAEELARNMAIQQELEKEK 146
           +++ +++ +E  + + E+++ +  KR  +E   + +E+K +E EE  +    ++++ +++
Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQ--EEKIREQE 632

Query: 147 QRVAQQKQQ-QLEQEQFHAFEEMIRNQE 173
           +++ +Q++  Q ++E+    EE +  QE
Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQE 660



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 6/83 (7%)

Query: 112 KRYTKEYTEYNEEKKKEAEELARNMAIQQELE----KEKQRVAQQKQQQLEQEQF--HAF 165
           KR  +E     EEK  E EE+ R      E E    K++++V +Q+++  EQE+      
Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530

Query: 166 EEMIRNQELEKERLKIVQEFGKV 188
           E+M R +E  +E+ ++ +E  K+
Sbjct: 531 EKMWRQEEKIREQEEMWREEEKM 553



 Score = 29.3 bits (64), Expect = 7.1
 Identities = 19/88 (21%), Positives = 48/88 (54%), Gaps = 7/88 (7%)

Query: 87  EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146
           E+++ +++ +E  + + E+++ +  K          EEK +E EE+ +    ++  E+E+
Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKK------IREQEEKIREQEEMMQEQE-EKMWEQEE 710

Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQEL 174
           +   Q+++ Q ++E+    EE +  QE+
Sbjct: 711 KMCEQEEKMQEQEEKMRRQEEKMWEQEV 738


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.388 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,250,894
Number of Sequences: 37866
Number of extensions: 828468
Number of successful extensions: 12826
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 277
Number of HSP's successfully gapped in prelim test: 610
Number of HSP's that attempted gapping in prelim test: 6238
Number of HSP's gapped (non-prelim): 4354
length of query: 424
length of database: 18,247,518
effective HSP length: 105
effective length of query: 319
effective length of database: 14,271,588
effective search space: 4552636572
effective search space used: 4552636572
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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