BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5453545 STAM binding protein [Homo sapiens] (424 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47132534 STAM binding protein [Homo sapiens] 855 0.0 gi|42519912 STAM binding protein [Homo sapiens] 855 0.0 gi|5453545 STAM binding protein [Homo sapiens] 855 0.0 gi|33147080 STAM binding protein-like 1 [Homo sapiens] 489 e-138 gi|116174778 centrosome spindle pole associated protein 1 isofor... 47 4e-05 gi|116174789 centrosome spindle pole associated protein 1 isofor... 47 4e-05 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 46 7e-05 gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] 45 1e-04 gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] 45 1e-04 gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] 45 1e-04 gi|22035606 mitogen-activated protein kinase kinase kinase kinas... 45 2e-04 gi|22035602 mitogen-activated protein kinase kinase kinase kinas... 45 2e-04 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 44 2e-04 gi|215982794 myosin VA isoform 2 [Homo sapiens] 44 2e-04 gi|215982791 myosin VA isoform 1 [Homo sapiens] 44 2e-04 gi|22035604 mitogen-activated protein kinase kinase kinase kinas... 44 3e-04 gi|153945728 microtubule-associated protein 1B [Homo sapiens] 44 4e-04 gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 44 4e-04 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 43 5e-04 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 43 5e-04 gi|148746195 trichohyalin [Homo sapiens] 43 6e-04 gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 43 6e-04 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 41 0.002 gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 41 0.002 gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 41 0.002 gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 41 0.002 gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 41 0.002 gi|32967605 bromodomain adjacent to zinc finger domain, 1A isofo... 41 0.002 gi|32967603 bromodomain adjacent to zinc finger domain, 1A isofo... 41 0.002 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 41 0.002 >gi|47132534 STAM binding protein [Homo sapiens] Length = 424 Score = 855 bits (2208), Expect = 0.0 Identities = 424/424 (100%), Positives = 424/424 (100%) Query: 1 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF Sbjct: 1 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60 Query: 61 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE Sbjct: 61 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120 Query: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK Sbjct: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 Query: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG Sbjct: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240 Query: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL Sbjct: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300 Query: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP Sbjct: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360 Query: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI Sbjct: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420 Query: 421 TDLR 424 TDLR Sbjct: 421 TDLR 424 >gi|42519912 STAM binding protein [Homo sapiens] Length = 424 Score = 855 bits (2208), Expect = 0.0 Identities = 424/424 (100%), Positives = 424/424 (100%) Query: 1 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF Sbjct: 1 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60 Query: 61 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE Sbjct: 61 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120 Query: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK Sbjct: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 Query: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG Sbjct: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240 Query: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL Sbjct: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300 Query: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP Sbjct: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360 Query: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI Sbjct: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420 Query: 421 TDLR 424 TDLR Sbjct: 421 TDLR 424 >gi|5453545 STAM binding protein [Homo sapiens] Length = 424 Score = 855 bits (2208), Expect = 0.0 Identities = 424/424 (100%), Positives = 424/424 (100%) Query: 1 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF Sbjct: 1 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60 Query: 61 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE Sbjct: 61 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120 Query: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK Sbjct: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 Query: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG Sbjct: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPG 240 Query: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL Sbjct: 241 ALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEFTITHVL 300 Query: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP Sbjct: 301 IPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCSYQMMLP 360 Query: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI Sbjct: 361 ESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVVDRAVTI 420 Query: 421 TDLR 424 TDLR Sbjct: 421 TDLR 424 >gi|33147080 STAM binding protein-like 1 [Homo sapiens] Length = 436 Score = 489 bits (1260), Expect = e-138 Identities = 240/430 (55%), Positives = 314/430 (73%), Gaps = 15/430 (3%) Query: 1 MSDHGDVSLPPEDRVRALSQLGSAVEVNEDIPPRRYFRSGVEIIRMASIYSEEGNIEHAF 60 M DH DVSL PE+RVRALS+LG + ++EDI PRRYFRSGVE+ RMAS+Y EEGN+E+AF Sbjct: 16 MPDHTDVSLSPEERVRALSKLGCNITISEDITPRRYFRSGVEMERMASVYLEEGNLENAF 75 Query: 61 ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE 120 +LYNK+ITLF+EKLP HRDY+ +PEK+D +KKLKEIAFP+ +ELK +LLK+Y EY E Sbjct: 76 VLYNKFITLFVEKLPNHRDYQQCAVPEKQDIMKKLKEIAFPRTDELKNDLLKKYNVEYQE 135 Query: 121 YNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 Y + K K E+ + + Q+ +E E++R+AQ +QQQLE EQF FE+ ++ QEL + +++ Sbjct: 136 YLQSKNKYKAEILKKLEHQRLIEAERKRIAQMRQQQLESEQFLFFEDQLKKQELARGQMR 195 Query: 181 IVQEFGKVDPGLGGPLVPDLEKPSLDVFPT------LTVSSIQPSDCHTTVRPAKPPVVD 234 Q G L ++ +L F T L V + QP+ T + P V+ Sbjct: 196 SQQTSG---------LSEQIDGSALSCFSTHQNNSLLNVFADQPNKSDATNYASHSPPVN 246 Query: 235 RSLKPGALSNSESIPTIDGLRHVVVPGRLCPQFLQLASANTARGVETCGILCGKLMRNEF 294 R+L P A ++ ++GLR VV+P LC +FLQLA +NT RG+ETCGILCGKL NEF Sbjct: 247 RALTPAATLSAVQNLVVEGLRCVVLPEDLCHKFLQLAESNTVRGIETCGILCGKLTHNEF 306 Query: 295 TITHVLIPKQSAGSDYCNTENEEELFLIQDQQGLITLGWIHTHPTQTAFLSSVDLHTHCS 354 TITHV++PKQSAG DYC+ EN EELF +QDQ L+TLGWIHTHPTQTAFLSSVDLHTHCS Sbjct: 307 TITHVIVPKQSAGPDYCDMENVEELFNVQDQHDLLTLGWIHTHPTQTAFLSSVDLHTHCS 366 Query: 355 YQMMLPESVAIVCSPKFQETGFFKLTDHGLEEISSCRQKGFHPHSKDPPLFCSCSHVTVV 414 YQ+MLPE++AIVCSPK ++TG F+LT+ G+ E+S+C++KGFHPH+K+P LF C HV V Sbjct: 367 YQLMLPEAIAIVCSPKHKDTGIFRLTNAGMLEVSACKKKGFHPHTKEPRLFSICKHVLVK 426 Query: 415 DRAVTITDLR 424 D + + DLR Sbjct: 427 DIKIIVLDLR 436 >gi|116174778 centrosome spindle pole associated protein 1 isoform b [Homo sapiens] Length = 1221 Score = 46.6 bits (109), Expect = 4e-05 Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 12/172 (6%) Query: 69 LFIEKLPKHRDYKSAVIPEKKDTVKKLKE---IAFPKAEELKAELLKRYTKEYTEYNEEK 125 L I++ ++++ I EKK + +E IA K E AE R +EY E E+K Sbjct: 727 LQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKK 786 Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEF 185 +++ EE L +E+Q+ A++K+++ E++ + L E K +++ Sbjct: 787 REKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQP 846 Query: 186 GKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCH--TTVRPAKPPVVDR 235 + P L + L++P +V SI S H + R PPV R Sbjct: 847 SPIVPALQNKIASKLQRPP-------SVDSIIRSFIHESSMSRAQSPPVPAR 891 >gi|116174789 centrosome spindle pole associated protein 1 isoform a [Homo sapiens] Length = 1256 Score = 46.6 bits (109), Expect = 4e-05 Identities = 44/172 (25%), Positives = 77/172 (44%), Gaps = 12/172 (6%) Query: 69 LFIEKLPKHRDYKSAVIPEKKDTVKKLKE---IAFPKAEELKAELLKRYTKEYTEYNEEK 125 L I++ ++++ I EKK + +E IA K E AE R +EY E E+K Sbjct: 762 LQIKQQELYKNFLRFQIEEKKQREEAERERLRIAEEKEERRLAEQRARIQQEYEEEQEKK 821 Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEF 185 +++ EE L +E+Q+ A++K+++ E++ + L E K +++ Sbjct: 822 REKEEEQRLKNEEHIRLAEERQKEAERKKKEEEEKYNLQLQHYCERDNLIGEETKHMRQP 881 Query: 186 GKVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCH--TTVRPAKPPVVDR 235 + P L + L++P +V SI S H + R PPV R Sbjct: 882 SPIVPALQNKIASKLQRPP-------SVDSIIRSFIHESSMSRAQSPPVPAR 926 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 45.8 bits (107), Expect = 7e-05 Identities = 34/105 (32%), Positives = 59/105 (56%), Gaps = 7/105 (6%) Query: 87 EKKDTVKKLKEIAFPKAEE---LKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE 143 E++D + E A +AEE +KAE K+ E E+K A+E R A ++E Sbjct: 258 EEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERM 317 Query: 144 KEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEK----ERLKIVQE 184 +E+++ A +++Q++++E+ A EE R +E EK ER +I +E Sbjct: 318 REEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEE 362 Score = 42.4 bits (98), Expect = 8e-04 Identities = 26/93 (27%), Positives = 58/93 (62%), Gaps = 9/93 (9%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E+++ +++ ++ A + + +K E KR +E EE+K+ AEE +Q +++E+ Sbjct: 312 EERERMREEEKRAAEERQRIKEEE-KRAAEERQRIKEEEKRAAEE-------RQRIKEEE 363 Query: 147 QRVAQQKQQ-QLEQEQFHAFEEMIRNQELEKER 178 +R A+++Q+ + E+E+ EE RN++LE+++ Sbjct: 364 KRAAEERQRARAEEEEKAKVEEQKRNKQLEEKK 396 Score = 41.6 bits (96), Expect = 0.001 Identities = 29/113 (25%), Positives = 63/113 (55%), Gaps = 9/113 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E+ K D ++ + E+K ++ + + E ++ E KR +E EE+K+ AEE Sbjct: 283 EQDKKIADERARIEAEEKAAAQERERREAEERERMREEE-KRAAEERQRIKEEEKRAAEE 341 Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 +Q +++E++R A+++ Q++++E+ A EE R + E+E+ K+ ++ Sbjct: 342 -------RQRIKEEEKRAAEER-QRIKEEEKRAAEERQRARAEEEEKAKVEEQ 386 Score = 40.8 bits (94), Expect = 0.002 Identities = 28/92 (30%), Positives = 54/92 (58%), Gaps = 6/92 (6%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E++ +K+ ++ A + + +K E KR +E EE+K+ AEE R A E+EK Sbjct: 326 EERQRIKEEEKRAAEERQRIKEEE-KRAAEERQRIKEEEKRAAEERQRARAE----EEEK 380 Query: 147 QRVAQQKQQQLEQEQFHAFEE-MIRNQELEKE 177 +V +QK+ + +E+ HA +E I+ +++E++ Sbjct: 381 AKVEEQKRNKQLEEKKHAMQETKIKGEKVEQK 412 Score = 34.7 bits (78), Expect = 0.17 Identities = 32/113 (28%), Positives = 56/113 (49%), Gaps = 5/113 (4%) Query: 79 DYKSAVIPEKKDTVKKLKEIAFPKAEELKAEL--LKRYTKEYTEYNEEKKKEAEELARNM 136 D K A + + K+L+E+ + E E LK+ +E EE KK+ EE R Sbjct: 520 DTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREE--RRK 577 Query: 137 AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVD 189 +++E ++ KQ A +K ++ E+E+ EE+ R + E+ + + E G D Sbjct: 578 VLEEEEQRRKQEEADRKLRE-EEEKRRLKEEIERRRAEAAEKRQKMPEDGLSD 629 Score = 31.6 bits (70), Expect = 1.4 Identities = 20/90 (22%), Positives = 47/90 (52%), Gaps = 3/90 (3%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 ++L + R + E+ + +K+ ++ A + EELK KR + EE++++ EE Sbjct: 534 KRLEELRRRRGETESEEFEKLKQKQQEAALELEELKK---KREERRKVLEEEEQRRKQEE 590 Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161 R + ++E + K+ + +++ + E+ Q Sbjct: 591 ADRKLREEEEKRRLKEEIERRRAEAAEKRQ 620 Score = 29.6 bits (65), Expect = 5.4 Identities = 24/119 (20%), Positives = 56/119 (47%), Gaps = 6/119 (5%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK---- 126 + K + D++ A +K+D K+ +E PK + ++ +E T ++E+ Sbjct: 168 VTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMS 227 Query: 127 -KEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 K + + ++E E+ ++ ++ + E+++ A E R + E+ER+K Q+ Sbjct: 228 LKNGQISSEEPKQEEEREQGSDEISHHEKME-EEDKERAEAERARLEAEERERIKAEQD 285 Score = 29.3 bits (64), Expect = 7.1 Identities = 21/107 (19%), Positives = 56/107 (52%), Gaps = 13/107 (12%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 EK ++ + EKK +++ K K E+++ ++ ++ E K+A+E Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQETKI----KGEKVEQKIEGKWVNE---------KKAQE 425 Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 A+ ++ +EK Q K+++L++++ +E I++++++K++ Sbjct: 426 DKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKIKKDK 472 >gi|190684694 ubiquitin specific peptidase 8 [Homo sapiens] Length = 1118 Score = 45.1 bits (105), Expect = 1e-04 Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 12/135 (8%) Query: 17 ALSQLGSAVEVN-EDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLF--IEK 73 +L L EV E I + Y S ++I + A + + E A++LY KY+T++ I+K Sbjct: 16 SLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKK 75 Query: 74 LP---KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 P + +DY +++ +KK A +AE L L RY + E+K E Sbjct: 76 RPDFKQQQDYFHSIL--GPGNIKK----AVEEAERLSESLKLRYEEAEVRKKLEEKDRQE 129 Query: 131 ELARNMAIQQELEKE 145 E R +QE +E Sbjct: 130 EAQRLQQKRQETGRE 144 Score = 30.0 bits (66), Expect = 4.1 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 7/122 (5%) Query: 84 VIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE-L 142 VIP++ K + F L E R E E+ K+E E R Q+E L Sbjct: 440 VIPDRST-----KPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKL 494 Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLEK 202 KE+Q +K+Q+ E+ + ++ + +E+EK+ + ++ K G + +++ Sbjct: 495 RKEEQEQKAKKKQEAEENEITEKQQKAK-EEMEKKESEQAKKEDKETSAKRGKEITGVKR 553 Query: 203 PS 204 S Sbjct: 554 QS 555 >gi|190684692 ubiquitin specific peptidase 8 [Homo sapiens] Length = 1118 Score = 45.1 bits (105), Expect = 1e-04 Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 12/135 (8%) Query: 17 ALSQLGSAVEVN-EDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLF--IEK 73 +L L EV E I + Y S ++I + A + + E A++LY KY+T++ I+K Sbjct: 16 SLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKK 75 Query: 74 LP---KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 P + +DY +++ +KK A +AE L L RY + E+K E Sbjct: 76 RPDFKQQQDYFHSIL--GPGNIKK----AVEEAERLSESLKLRYEEAEVRKKLEEKDRQE 129 Query: 131 ELARNMAIQQELEKE 145 E R +QE +E Sbjct: 130 EAQRLQQKRQETGRE 144 Score = 30.0 bits (66), Expect = 4.1 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 7/122 (5%) Query: 84 VIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE-L 142 VIP++ K + F L E R E E+ K+E E R Q+E L Sbjct: 440 VIPDRST-----KPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKL 494 Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLEK 202 KE+Q +K+Q+ E+ + ++ + +E+EK+ + ++ K G + +++ Sbjct: 495 RKEEQEQKAKKKQEAEENEITEKQQKAK-EEMEKKESEQAKKEDKETSAKRGKEITGVKR 553 Query: 203 PS 204 S Sbjct: 554 QS 555 >gi|190684690 ubiquitin specific peptidase 8 [Homo sapiens] Length = 1118 Score = 45.1 bits (105), Expect = 1e-04 Identities = 39/135 (28%), Positives = 63/135 (46%), Gaps = 12/135 (8%) Query: 17 ALSQLGSAVEVN-EDIPPRRYFRSGVEIIRMASIYSEEGNIEHAFILYNKYITLF--IEK 73 +L L EV E I + Y S ++I + A + + E A++LY KY+T++ I+K Sbjct: 16 SLKDLNKKTEVKPEKISTKSYVHSALKIFKTAEECRLDRDEERAYVLYMKYVTVYNLIKK 75 Query: 74 LP---KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 P + +DY +++ +KK A +AE L L RY + E+K E Sbjct: 76 RPDFKQQQDYFHSIL--GPGNIKK----AVEEAERLSESLKLRYEEAEVRKKLEEKDRQE 129 Query: 131 ELARNMAIQQELEKE 145 E R +QE +E Sbjct: 130 EAQRLQQKRQETGRE 144 Score = 30.0 bits (66), Expect = 4.1 Identities = 29/122 (23%), Positives = 54/122 (44%), Gaps = 7/122 (5%) Query: 84 VIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE-L 142 VIP++ K + F L E R E E+ K+E E R Q+E L Sbjct: 440 VIPDRST-----KPVVFSPTLMLTDEEKARIHAETALLMEKNKQEKELRERQQEEQKEKL 494 Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLEK 202 KE+Q +K+Q+ E+ + ++ + +E+EK+ + ++ K G + +++ Sbjct: 495 RKEEQEQKAKKKQEAEENEITEKQQKAK-EEMEKKESEQAKKEDKETSAKRGKEITGVKR 553 Query: 203 PS 204 S Sbjct: 554 QS 555 >gi|22035606 mitogen-activated protein kinase kinase kinase kinase 4 isoform 3 [Homo sapiens] Length = 1212 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/116 (25%), Positives = 66/116 (56%), Gaps = 10/116 (8%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIA--FPKAEELKAELLKRYTKEYTEYNEEKKKEA 129 ++L + +YK ++ E++ +++ KE + + + E ++ +E +E+K+ Sbjct: 379 QQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRL 438 Query: 130 EELARNMAIQQE---LEKEKQRVAQQKQ---QQLEQEQFHAFEEMIRNQELEKERL 179 EEL R ++E E+EK+RV ++++ +QLE+EQ H E+++ Q L+++ + Sbjct: 439 EELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL--EVLQQQLLQEQAM 492 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 8/95 (8%) Query: 95 LKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQ 154 L+E + EE K +LL K + E++++ E QQ E+E +R +++Q Sbjct: 376 LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE--------QQRREREARRQQEREQ 427 Query: 155 QQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVD 189 ++ EQE+ EE+ R ++ E+ER + +E +V+ Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462 Score = 32.0 bits (71), Expect = 1.1 Identities = 22/113 (19%), Positives = 56/113 (49%), Gaps = 8/113 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E++P+ S+++ ++ + + + + ++E L+R E++ +E EE Sbjct: 331 EEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQL----LQEQQLREQEE 386 Query: 132 LARNMAIQQ----ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 R + ++ E +KE++R +++Q++ + + E R ++ EK RL+ Sbjct: 387 YKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439 >gi|22035602 mitogen-activated protein kinase kinase kinase kinase 4 isoform 1 [Homo sapiens] Length = 1166 Score = 44.7 bits (104), Expect = 2e-04 Identities = 29/116 (25%), Positives = 66/116 (56%), Gaps = 10/116 (8%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIA--FPKAEELKAELLKRYTKEYTEYNEEKKKEA 129 ++L + +YK ++ E++ +++ KE + + + E ++ +E +E+K+ Sbjct: 379 QQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRL 438 Query: 130 EELARNMAIQQE---LEKEKQRVAQQKQ---QQLEQEQFHAFEEMIRNQELEKERL 179 EEL R ++E E+EK+RV ++++ +QLE+EQ H E+++ Q L+++ + Sbjct: 439 EELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHL--EVLQQQLLQEQAM 492 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 8/95 (8%) Query: 95 LKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQ 154 L+E + EE K +LL K + E++++ E QQ E+E +R +++Q Sbjct: 376 LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE--------QQRREREARRQQEREQ 427 Query: 155 QQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVD 189 ++ EQE+ EE+ R ++ E+ER + +E +V+ Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462 Score = 32.0 bits (71), Expect = 1.1 Identities = 22/113 (19%), Positives = 56/113 (49%), Gaps = 8/113 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E++P+ S+++ ++ + + + + ++E L+R E++ +E EE Sbjct: 331 EEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQL----LQEQQLREQEE 386 Query: 132 LARNMAIQQ----ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 R + ++ E +KE++R +++Q++ + + E R ++ EK RL+ Sbjct: 387 YKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 44.3 bits (103), Expect = 2e-04 Identities = 34/104 (32%), Positives = 55/104 (52%), Gaps = 9/104 (8%) Query: 72 EKLPKHRDYKSAVIPEKK--DTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEA 129 E++ K R+ K EKK D +K++E E ++ K +E T +E+K + Sbjct: 421 EQVEKMREEKKMQEQEKKTRDQEEKMQE-----EERIREREKKMREEEETMREQEEKMQK 475 Query: 130 EELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173 +E NM Q+E E ++QR+ +QK++ EQE+ EE I QE Sbjct: 476 QE--ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQE 517 Score = 37.0 bits (84), Expect = 0.034 Identities = 26/114 (22%), Positives = 55/114 (48%), Gaps = 1/114 (0%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 EKLP KS + K+ +KL+ F + L + ++ E E++KK ++ Sbjct: 232 EKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQ 291 Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQE-QFHAFEEMIRNQELEKERLKIVQE 184 + ++ L +++ ++ +Q+++ QE + E+ +R QE E K ++E Sbjct: 292 EEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELRE 345 Score = 37.0 bits (84), Expect = 0.034 Identities = 26/105 (24%), Positives = 58/105 (55%), Gaps = 7/105 (6%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK-----KEAEELARNMAIQQE 141 E++ ++K +E + + E L+ + K +E + +EK+ KE E + + Q+E Sbjct: 283 EQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKE 342 Query: 142 LEKEKQRVAQQKQQQLEQEQ--FHAFEEMIRNQELEKERLKIVQE 184 L ++++++ +Q+++ EQE+ E+M R +E E+ K ++E Sbjct: 343 LREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 387 Score = 35.0 bits (79), Expect = 0.13 Identities = 25/120 (20%), Positives = 59/120 (49%), Gaps = 3/120 (2%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEI---AFPKAEELKAELLKRYTKEYTEYNEEKKKE 128 E+ K RD + + +++ KK +E + + E+++ E R ++ EE +E Sbjct: 548 EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMRE 607 Query: 129 AEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188 EE + + + ++EK ++K Q+ E++ + E+M +E E+ ++ ++ K+ Sbjct: 608 QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKL 667 Score = 34.7 bits (78), Expect = 0.17 Identities = 31/114 (27%), Positives = 62/114 (54%), Gaps = 7/114 (6%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E+ K R+ + + ++K ++ KE+ + +EL+ + R +E + EEK E EE Sbjct: 304 EQEGKMREQEEKMWRQEKRLREQEKELR-EQEKELREQKELREQEEQMQEQEEKMWEQEE 362 Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQ-FHAFEEMIRNQELEKERLKIVQE 184 R ++++ ++++R+ +Q++Q EQEQ EE + Q+ ERL+ +E Sbjct: 363 KMREQ--EEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQD---ERLREKEE 411 Score = 34.7 bits (78), Expect = 0.17 Identities = 23/98 (23%), Positives = 53/98 (54%), Gaps = 2/98 (2%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 EK++ +++ +E + + E+++ E + ++ T EEK +E EE R + E+E Sbjct: 408 EKEERMRE-QEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQE-EERIREREKKMREEEET 465 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 R ++K Q+ E+ + E+ + Q L +++ K+ ++ Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503 Score = 33.9 bits (76), Expect = 0.29 Identities = 28/118 (23%), Positives = 66/118 (55%), Gaps = 14/118 (11%) Query: 85 IPEKKDTV---KKLKEIAFPKAEELKA---ELLKRYTKEYTE--YNEEKKKEAE---ELA 133 +PE+K+ + +K++E + +E K E +++ T+E + +++EK +E E E Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719 Query: 134 RNMAIQQEL---EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188 + M ++E+ ++EK + ++K Q+ E+E + E+M +E E+ ++ ++ K+ Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKL 777 Score = 33.5 bits (75), Expect = 0.38 Identities = 26/111 (23%), Positives = 60/111 (54%), Gaps = 10/111 (9%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 +EK + ++ K+ EK ++++E EE E + R +E + EEK +E E Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREE---EEMMREQEEKMQEQEEKMQEQE 623 Query: 131 ELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181 E + +++++++++++ +Q+++ EQE E+M Q L +++ K+ Sbjct: 624 E--KMWEQEEKMQEQEEKMWEQEEKMWEQE-----EKMWEQQRLPEQKEKL 667 Score = 33.1 bits (74), Expect = 0.49 Identities = 23/96 (23%), Positives = 55/96 (57%), Gaps = 4/96 (4%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E+++ +++ +E + E+++ + K + +E E +E++++ E M Q+E E+ Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQE--EKMQEQEEKMWEQEEKMWEQEEKMWEQ 657 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE--LEKERLK 180 QR+ +QK++ E E+ E+M +E E+E+++ Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKME 693 Score = 33.1 bits (74), Expect = 0.49 Identities = 30/96 (31%), Positives = 51/96 (53%), Gaps = 13/96 (13%) Query: 89 KDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQR 148 ++ KK++E EE+ E ++ +E E +E+++E E M Q+E E+QR Sbjct: 716 REREKKMRE-----EEEMMREQEEKM-QEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769 Query: 149 VAQQK------QQQLEQEQFHAFEEMIRNQELEKER 178 + +QK ++ EQE+ EE +R+QE EK R Sbjct: 770 LPEQKEKLWEHEKMQEQEKIWEQEEKMRDQE-EKMR 804 Score = 32.3 bits (72), Expect = 0.84 Identities = 23/93 (24%), Positives = 53/93 (56%), Gaps = 9/93 (9%) Query: 87 EKKDTVKKLKEIAFPKAEE------LKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQ 140 E+++ ++K +E + + E+ L + K + +E + EEK E EE R+ Q+ Sbjct: 468 EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRD---QE 524 Query: 141 ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173 E+ +++++ +Q++ + +++Q EE +R+QE Sbjct: 525 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQE 557 Score = 31.2 bits (69), Expect = 1.9 Identities = 27/119 (22%), Positives = 57/119 (47%), Gaps = 12/119 (10%) Query: 76 KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARN 135 + ++++ +PE+K+ K ++ + EE E ++ + + +EKK +E R Sbjct: 484 EEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMRE 541 Query: 136 MAIQQELEKEKQRVAQQ----------KQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 Q ++EK R +Q K+ Q ++++ EE +R +E +ER K ++E Sbjct: 542 QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600 Score = 31.2 bits (69), Expect = 1.9 Identities = 20/102 (19%), Positives = 47/102 (46%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 EK+ + D + +D +K+ + ++ + + K + +E EE+ +E E+ Sbjct: 537 EKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREK 596 Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173 R ++EK + ++K Q+ E++ + E+M +E Sbjct: 597 KMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638 Score = 30.0 bits (66), Expect = 4.1 Identities = 24/103 (23%), Positives = 54/103 (52%), Gaps = 3/103 (2%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E++ +++ KE+ + + + E +E EEK EE R ++++ +++ Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE--RLWEQEKQMREQE 389 Query: 147 QRVAQQKQQQLEQ-EQFHAFEEMIRNQELEKERLKIVQEFGKV 188 Q++ Q+++ EQ E+ EE +R QE E+++ ++E K+ Sbjct: 390 QKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKM 432 Score = 29.3 bits (64), Expect = 7.1 Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 14/111 (12%) Query: 82 SAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE 141 SAV K + ++E+ +E A L+ Y T NEE KK+ EL + + + Sbjct: 186 SAVSTRHKKADRYIEELT----KERDALSLELYRNTIT--NEELKKKNAELQEKLPLAES 239 Query: 142 LEKEKQRVAQQKQQQLEQEQF--------HAFEEMIRNQELEKERLKIVQE 184 + E Q ++ +++LE+ +F EEM R +E +E+ K +++ Sbjct: 240 EKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 290 Score = 29.3 bits (64), Expect = 7.1 Identities = 19/100 (19%), Positives = 55/100 (55%), Gaps = 6/100 (6%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYT--EYNEEKKKEAEELARNMAIQQELEK 144 E+++ + + +E + + ++++ + K +E E +E +++ E + + +++EK Sbjct: 366 EQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEK 425 Query: 145 EKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 ++ Q+Q++ ++Q EE ++ +E +ER K ++E Sbjct: 426 MREEKKMQEQEKKTRDQ----EEKMQEEERIREREKKMRE 461 Score = 28.9 bits (63), Expect = 9.2 Identities = 18/87 (20%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E+++ +++ +E + + E++ + K + ++ +EK E E++ I ++ EK + Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE 173 Q+++ + ++E+ EE +R QE Sbjct: 798 D---QEEKMRGQEEKMRGQEEKMRGQE 821 >gi|215982794 myosin VA isoform 2 [Homo sapiens] Length = 1828 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 14/133 (10%) Query: 82 SAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE 141 S+ I E +D + +E + K L L + K TE +EK+ +Q E Sbjct: 1127 SSEIAEMEDIPSRTEEPSEKKVP-LDMSLFLKLQKRVTELEQEKQ----------VMQDE 1175 Query: 142 LEKEKQRVAQQKQQQLEQEQFHAFE---EMIRNQELEKERLKIVQEFGKVDPGLGGPLVP 198 L++++++V + K ++ E+ Q E E ++ QELE E K+ E ++ L P Sbjct: 1176 LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAP 1235 Query: 199 DLEKPSLDVFPTL 211 ++ P + L Sbjct: 1236 EVTAPGAPAYRVL 1248 Score = 30.0 bits (66), Expect = 4.1 Identities = 21/79 (26%), Positives = 41/79 (51%), Gaps = 9/79 (11%) Query: 120 EYNEEKKKEAEELARNM-----AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQ-E 173 E+ + K+E E+L N+ ++QE E R+ QQ ++ E + EE + + + Sbjct: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELD 1070 Query: 174 LEKERLK---IVQEFGKVD 189 L ERL+ ++ EF +++ Sbjct: 1071 LNDERLRYQNLLNEFSRLE 1089 >gi|215982791 myosin VA isoform 1 [Homo sapiens] Length = 1855 Score = 44.3 bits (103), Expect = 2e-04 Identities = 33/133 (24%), Positives = 60/133 (45%), Gaps = 14/133 (10%) Query: 82 SAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQE 141 S+ I E +D + +E + K L L + K TE +EK+ +Q E Sbjct: 1127 SSEIAEMEDIPSRTEEPSEKKVP-LDMSLFLKLQKRVTELEQEKQ----------VMQDE 1175 Query: 142 LEKEKQRVAQQKQQQLEQEQFHAFE---EMIRNQELEKERLKIVQEFGKVDPGLGGPLVP 198 L++++++V + K ++ E+ Q E E ++ QELE E K+ E ++ L P Sbjct: 1176 LDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAP 1235 Query: 199 DLEKPSLDVFPTL 211 ++ P + L Sbjct: 1236 EVTAPGAPAYRVL 1248 Score = 30.0 bits (66), Expect = 4.1 Identities = 21/79 (26%), Positives = 41/79 (51%), Gaps = 9/79 (11%) Query: 120 EYNEEKKKEAEELARNM-----AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQ-E 173 E+ + K+E E+L N+ ++QE E R+ QQ ++ E + EE + + + Sbjct: 1011 EHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELD 1070 Query: 174 LEKERLK---IVQEFGKVD 189 L ERL+ ++ EF +++ Sbjct: 1071 LNDERLRYQNLLNEFSRLE 1089 >gi|22035604 mitogen-activated protein kinase kinase kinase kinase 4 isoform 2 [Homo sapiens] Length = 1320 Score = 43.9 bits (102), Expect = 3e-04 Identities = 27/95 (28%), Positives = 51/95 (53%), Gaps = 8/95 (8%) Query: 95 LKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQ 154 L+E + EE K +LL K + E++++ E QQ E+E +R +++Q Sbjct: 376 LQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE--------QQRREREARRQQEREQ 427 Query: 155 QQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVD 189 ++ EQE+ EE+ R ++ E+ER + +E +V+ Sbjct: 428 RRREQEEKRRLEELERRRKEEEERRRAEEEKRRVE 462 Score = 35.4 bits (80), Expect = 0.099 Identities = 33/140 (23%), Positives = 65/140 (46%), Gaps = 28/140 (20%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIA--FPKAEELKAELLKRYTKEYTEYNEEKKKEA 129 ++L + +YK ++ E++ +++ KE + + + E ++ +E +E+K+ Sbjct: 379 QQLREQEEYKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRL 438 Query: 130 EELARNMA---------------------IQQELEKEKQRVAQQKQQQLEQEQFHAFE-- 166 EEL R I+++LE E+QR + QQQL QEQ E Sbjct: 439 EELERRRKEEEERRRAEEEKRRVEREQEYIRRQLE-EEQRHLEVLQQQLLQEQAMLLECR 497 Query: 167 --EMIRNQELEKERLKIVQE 184 EM +++ E+ + ++ QE Sbjct: 498 WREMEEHRQAERLQRQLQQE 517 Score = 33.1 bits (74), Expect = 0.49 Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 11/86 (12%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYN----EEKKKEAEELARNMAIQQEL 142 E+K +++L+ + E +AE KR + EY EE+++ E L + + +Q + Sbjct: 433 EEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQLEEEQRHLEVLQQQLLQEQAM 492 Query: 143 -------EKEKQRVAQQKQQQLEQEQ 161 E E+ R A++ Q+QL+QEQ Sbjct: 493 LLECRWREMEEHRQAERLQRQLQQEQ 518 Score = 32.0 bits (71), Expect = 1.1 Identities = 22/113 (19%), Positives = 56/113 (49%), Gaps = 8/113 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E++P+ S+++ ++ + + + + ++E L+R E++ +E EE Sbjct: 331 EEVPEQEGEPSSIVNVPGESTLRRDFLRLQQENKERSEALRRQQL----LQEQQLREQEE 386 Query: 132 LARNMAIQQ----ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 R + ++ E +KE++R +++Q++ + + E R ++ EK RL+ Sbjct: 387 YKRQLLAERQKRIEQQKEQRRRLEEQQRREREARRQQEREQRRREQEEKRRLE 439 >gi|153945728 microtubule-associated protein 1B [Homo sapiens] Length = 2468 Score = 43.5 bits (101), Expect = 4e-04 Identities = 41/171 (23%), Positives = 77/171 (45%), Gaps = 18/171 (10%) Query: 72 EKLPKHRDYKSAVIPE-----KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK 126 E+ PK + K V E KK+ K++K+ PK E+K E+ K KE + +E K Sbjct: 672 EEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPK--EVKKEVKKEEKKEVKKEEKEPK 729 Query: 127 KEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFG 186 KE ++L ++ E ++ A K + ++E+ + + + EK ++K++++ G Sbjct: 730 KEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEG 789 Query: 187 KVDPGLGGPLVPDLEKPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSL 237 K E + V T +++ + + PAK +RSL Sbjct: 790 KA-----------AEAVAAAVGTGATTAAVMAAAGIAAIGPAKELEAERSL 829 Score = 36.6 bits (83), Expect = 0.044 Identities = 22/87 (25%), Positives = 48/87 (55%), Gaps = 2/87 (2%) Query: 76 KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEK--KKEAEELA 133 K D K KK+ KK + K E+ K E +K+ K+ + E+K KKE ++ Sbjct: 645 KPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKET 704 Query: 134 RNMAIQQELEKEKQRVAQQKQQQLEQE 160 +++E++KE+++ ++++++ ++E Sbjct: 705 PPKEVKKEVKKEEKKEVKKEEKEPKKE 731 Score = 32.7 bits (73), Expect = 0.64 Identities = 39/167 (23%), Positives = 75/167 (44%), Gaps = 19/167 (11%) Query: 86 PEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE-YNEEKKKEAEELAR---NMAIQQE 141 P K + +K PKA K + +K+ TK E EEK+K +E+A+ I++E Sbjct: 615 PVKAEVAEKQATDVKPKAA--KEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKE 672 Query: 142 LEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGGPLVPDLE 201 + +K+ V ++ ++++++E+ ++ ++ + KE K V++ K + V E Sbjct: 673 EKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKE-------VKKEE 725 Query: 202 KPSLDVFPTLTVSSIQPSDCHTTVRPAKPPVVDRSLKPGALSNSESI 248 K P + + P D + P +LKP ES+ Sbjct: 726 KE-----PKKEIKKL-PKDAKKSSTPLSEAKKPAALKPKVPKKEESV 766 Score = 29.6 bits (65), Expect = 5.4 Identities = 33/131 (25%), Positives = 53/131 (40%), Gaps = 1/131 (0%) Query: 75 PKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELAR 134 PK K+ K K +E PK E K E KE EE KKE ++ + Sbjct: 630 PKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIK 689 Query: 135 NMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKVDPGLGG 194 ++E +KE ++ K+ + E ++ E +E +KE K+ ++ K L Sbjct: 690 KEE-KKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSE 748 Query: 195 PLVPDLEKPSL 205 P KP + Sbjct: 749 AKKPAALKPKV 759 >gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] Length = 495 Score = 43.5 bits (101), Expect = 4e-04 Identities = 40/149 (26%), Positives = 73/149 (48%), Gaps = 9/149 (6%) Query: 38 RSGVEIIRMASIYSEEGNIEHAFILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKE 97 R +E +R +Y EE A I +K +KL K ++ K E++ +K+L Sbjct: 313 REDLEQVRQ-ELYQEE----QAEIYKSKLKEEAEKKLRKQKEMKQDF--EEQMALKELVL 365 Query: 98 IAFPKAEE--LKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQ 155 A + EE K L K + E +K+ ++L A+++ +E+ +Q+ KQ+ Sbjct: 366 QAAKEEEENFRKTMLAKFAEDDRIELMNAQKQRMKQLEHRRAVEKLIEERRQQFLADKQR 425 Query: 156 QLEQEQFHAFEEMIRNQELEKERLKIVQE 184 +LE+ Q + N +E+ERLK+++E Sbjct: 426 ELEEWQLQQRRQGFINAIIEEERLKLLKE 454 Score = 37.4 bits (85), Expect = 0.026 Identities = 34/130 (26%), Positives = 70/130 (53%), Gaps = 17/130 (13%) Query: 72 EKLPKHRDYKSAVIPEK---KDTVKKL-KEIAFPKAEEL-KAELLKRYTKEYTE----YN 122 E+ K ++ ++ EK + V+K+ +E K ++L K ++RY +E+ + + Sbjct: 197 EQEKKKQEAYEQLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWR 256 Query: 123 EEKKKEAEELARNMA----IQQELEKEKQRVAQQKQQ---QLEQEQFHAFEEMIRNQE-L 174 ++K++E EE R + +QQ+ E+++ Q+ ++ QL+ EEM+R +E L Sbjct: 257 KKKREEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQKLEEMLRQREDL 316 Query: 175 EKERLKIVQE 184 E+ R ++ QE Sbjct: 317 EQVRQELYQE 326 Score = 35.4 bits (80), Expect = 0.099 Identities = 27/104 (25%), Positives = 55/104 (52%), Gaps = 11/104 (10%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 +K + K+LKE+ + E+L EL K ++ +EK + +++ N +ELEK+ Sbjct: 74 QKAEENKRLKELQLKQEEKLAMELAK---LKHESLKDEKMR--QQVRENSIELRELEKKL 128 Query: 147 QRVAQQKQQ--QLEQEQFHAFEEMIRNQELEK----ERLKIVQE 184 + K++ Q+ ++ +E+M R+ E+ K E +I++E Sbjct: 129 KAAYMNKERAAQIAEKDAIKYEQMKRDAEIAKTMMEEHKRIIKE 172 Score = 33.9 bits (76), Expect = 0.29 Identities = 32/125 (25%), Positives = 61/125 (48%), Gaps = 15/125 (12%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E++ + + ++ E K +K+ + A K + KA+ K+ E E+KK+EA E Sbjct: 150 EQMKRDAEIAKTMMEEHKRIIKE-ENAAEDKRNKAKAQYYLDLEKQLEEQ-EKKKQEAYE 207 Query: 132 --LARNMAIQQELEKEKQRVAQQKQQQLEQ--------EQFHAFEEMIR---NQELEKER 178 L + I + + K + +KQQ+LE+ E+F + + R +E+E+E Sbjct: 208 QLLKEKLMIDEIVRKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKREEMEEEN 267 Query: 179 LKIVQ 183 KI++ Sbjct: 268 RKIIE 272 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 43.1 bits (100), Expect = 5e-04 Identities = 23/112 (20%), Positives = 65/112 (58%), Gaps = 10/112 (8%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEEL----------ARNM 136 EK++ +++L+E+ + K E+++ K + +E EEK++E E++ A+ Sbjct: 360 EKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 419 Query: 137 AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188 ++++ ++++++ +Q+++ QE+ +E IR +E +E+ ++ ++ K+ Sbjct: 420 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 471 Score = 38.5 bits (88), Expect = 0.012 Identities = 22/87 (25%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 EK++ +++ +E+ + K E+++ + KE E+K +E R Q+E +E+ Sbjct: 346 EKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIRE---QEEKRQEE 402 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE 173 +++ +Q+++Q ++ + EE IR QE Sbjct: 403 EKIREQEKRQEQEAKMWRQEEKIREQE 429 Score = 36.6 bits (83), Expect = 0.044 Identities = 24/109 (22%), Positives = 62/109 (56%), Gaps = 8/109 (7%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK-KEAEELARNM-----AIQQE 141 +++ ++K +E + + E++ + K +E + +E+K +E EE R ++ Sbjct: 486 EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEM 545 Query: 142 LEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE--LEKERLKIVQEFGKV 188 ++++++++ +Q+++ EQE+ EE IR QE + +++ KI ++ K+ Sbjct: 546 MQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594 Score = 36.2 bits (82), Expect = 0.058 Identities = 33/130 (25%), Positives = 64/130 (49%), Gaps = 12/130 (9%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKA-ELLKRYTKEYTEYNEEKK-KE 128 +E++ ++ K + EK +K++E + EE K E KR +E + +E+K +E Sbjct: 368 LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 427 Query: 129 AEELARNMAI----------QQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 EE R +QE +E+++ +Q++ ++E+ EE+ R +E E+ Sbjct: 428 QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487 Query: 179 LKIVQEFGKV 188 KI ++ KV Sbjct: 488 EKIRKQEEKV 497 Score = 35.4 bits (80), Expect = 0.099 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 19/158 (12%) Query: 43 IIRMASIYSEEGNIEHAF---ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIA 99 I R+ + G +E A K +IE+L K RD S + T ++LKE Sbjct: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223 Query: 100 FPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE-------KEKQRVAQQ 152 E+L+ L K + N ++ K E A+ + QQ+L+ KE Q V+ + Sbjct: 224 AKLQEKLQ---LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280 Query: 153 KQQQLEQEQF------HAFEEMIRNQELEKERLKIVQE 184 Q Q+E+ + E+M R +E +E + +QE Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318 Score = 35.4 bits (80), Expect = 0.099 Identities = 19/51 (37%), Positives = 32/51 (62%), Gaps = 4/51 (7%) Query: 123 EEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173 EEK++E EE+ R Q+E +E++ + +QK++ EQE+ EE + QE Sbjct: 455 EEKRQEQEEMWR----QEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQE 501 Score = 35.0 bits (79), Expect = 0.13 Identities = 22/90 (24%), Positives = 50/90 (55%), Gaps = 10/90 (11%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEK 144 I E+++ +++ +E+ + E++ + K +E EEK +E EE ++ + Sbjct: 532 IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEE---------KIRE 582 Query: 145 EKQRVAQQKQQQLEQEQ-FHAFEEMIRNQE 173 +K+++ +Q+++ EQE+ EEM++ QE Sbjct: 583 QKEKIREQEEKIWEQEEKIREQEEMMQEQE 612 Score = 34.7 bits (78), Expect = 0.17 Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 5/63 (7%) Query: 112 KRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-FHAFEEMIR 170 KR +E EEK +E EE+ R Q+E E++++ +Q+++ QE+ H EE IR Sbjct: 457 KRQEQEEMWRQEEKIREQEEIWR----QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIR 512 Query: 171 NQE 173 QE Sbjct: 513 EQE 515 Score = 33.5 bits (75), Expect = 0.38 Identities = 21/94 (22%), Positives = 49/94 (52%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEK 144 I E+++ +++ +E + E+++ + R +E EEK +E +E R + ++ Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQE 598 Query: 145 EKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 EK R ++ Q+ E++ + E+M +E +E+ Sbjct: 599 EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 632 Score = 30.8 bits (68), Expect = 2.4 Identities = 23/103 (22%), Positives = 58/103 (56%), Gaps = 6/103 (5%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145 ++++ +++ +E + E+++ + K R +E EEK +E EE+ + ++ E+E Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE-EKMWEQE 619 Query: 146 KQRVAQQKQQQLEQEQFHAFEEMIRNQEL----EKERLKIVQE 184 ++ Q+++ Q ++E+ EE + QE+ ++E+++ QE Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662 Score = 30.4 bits (67), Expect = 3.2 Identities = 20/87 (22%), Positives = 51/87 (58%), Gaps = 4/87 (4%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147 +++ +++ +EI K + + E +++ +E EEK + EE R ++++ ++++ Sbjct: 467 QEEKIREQEEIWRQKEKMHEQEKIRKQ-EEKVWRQEEKMHDQEEKIREQ--EEKMWRQEE 523 Query: 148 RVAQQKQQQLEQEQ-FHAFEEMIRNQE 173 ++ +Q+++ EQE+ EEM++ QE Sbjct: 524 KIREQEEKIREQEEKIREQEEMMQEQE 550 Score = 30.4 bits (67), Expect = 3.2 Identities = 18/87 (20%), Positives = 49/87 (56%), Gaps = 3/87 (3%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147 +++ +++ +E + E+++ + +E +E+K + +E R ++++ ++++ Sbjct: 521 QEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQ--EEKIREQEE 578 Query: 148 RVAQQKQQQLEQEQ-FHAFEEMIRNQE 173 ++ +QK++ EQE+ EE IR QE Sbjct: 579 KIREQKEKIREQEEKIWEQEEKIREQE 605 Score = 30.4 bits (67), Expect = 3.2 Identities = 21/89 (23%), Positives = 44/89 (49%), Gaps = 6/89 (6%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEK 144 I E+K+ +++ +E + + E+++ + +E + EEK E EE + + ++ Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQ------EEMMQEQEEKMWEQEEKMCEQEEKMQEQE 633 Query: 145 EKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173 EK R ++K + E E+M +QE Sbjct: 634 EKMRRQEEKMWEQEVRLRQQEEKMQEHQE 662 Score = 30.0 bits (66), Expect = 4.1 Identities = 28/131 (21%), Positives = 68/131 (51%), Gaps = 13/131 (9%) Query: 67 ITLFIEKLPKHRDYKSAVIPEKKDTV------KKLKEIAFP-KAEELKAELLKRYTKEYT 119 I L +++L + + ++P+++ K+L+ ++ +A+ + EL R ++ Sbjct: 240 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 299 Query: 120 EY---NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQEL-- 174 E EEK +E EE + + ++EK R ++K ++ E+ + E+M R +E+ Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359 Query: 175 -EKERLKIVQE 184 ++E+++ ++E Sbjct: 360 EKEEKMRRLEE 370 Score = 29.3 bits (64), Expect = 7.1 Identities = 22/75 (29%), Positives = 41/75 (54%), Gaps = 9/75 (12%) Query: 116 KEYTEYNEEKKKEAEELARN----MAIQQEL--EKEKQRVAQQKQQQLEQEQFHAFEEMI 169 +E + EEK +E EE R M Q+E+ EKE++ Q++ ++E+ EEM+ Sbjct: 313 EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMM 372 Query: 170 RNQELEKERLKIVQE 184 +E E+++ ++E Sbjct: 373 WEKE---EKIRELEE 384 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 43.1 bits (100), Expect = 5e-04 Identities = 32/127 (25%), Positives = 68/127 (53%), Gaps = 8/127 (6%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 EKL K D K ++ EK+ + ++++E K E + EL K +E + E+ ++ +E Sbjct: 483 EKL-KRLDEKLGIL-EKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQE 540 Query: 132 LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQ------ELEKERLKIVQEF 185 + + +QE ++E ++ +Q++++ + Q +E+ + + ELEKER K+ ++ Sbjct: 541 KEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKI 600 Query: 186 GKVDPGL 192 +P L Sbjct: 601 EPREPNL 607 Score = 39.3 bits (90), Expect = 0.007 Identities = 33/110 (30%), Positives = 58/110 (52%), Gaps = 6/110 (5%) Query: 76 KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARN 135 K R+ + + E++ +K +E + +E + EL K K+ E K+++ +EL R Sbjct: 511 KEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER- 569 Query: 136 MAIQQELEKEKQRV-AQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 Q+E EKE Q++ Q+K+ +LE+E+ EE I +E E + QE Sbjct: 570 ---QKEKEKELQKMKEQEKECELEKER-EKLEEKIEPREPNLEPMVEKQE 615 Score = 33.5 bits (75), Expect = 0.38 Identities = 29/113 (25%), Positives = 58/113 (51%), Gaps = 7/113 (6%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELK----AELLKRYTKEYTEYNEEKKK 127 +++ K R + + I + +K +E + EE + AE LKR ++ EK+ Sbjct: 442 DEIWKQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLDEKLGIL--EKQP 499 Query: 128 EAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 EE+ R ++E E+EK+ +Q+Q++ ++ + + + +ELEKE+ K Sbjct: 500 SPEEI-REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEK 551 Score = 29.6 bits (65), Expect = 5.4 Identities = 25/98 (25%), Positives = 43/98 (43%), Gaps = 7/98 (7%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 EK+ +K KE+ K +E + + +K KE E +K E + R ++ +EK Sbjct: 556 EKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEK-- 613 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 Q+ + +E+ F N+ EKE +V E Sbjct: 614 ----QESENSCNKEEEPVFTRQDSNRS-EKEATPVVHE 646 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 42.7 bits (99), Expect = 6e-04 Identities = 23/79 (29%), Positives = 47/79 (59%), Gaps = 2/79 (2%) Query: 104 EELKAELLKRYTKEYTEY--NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161 EE + +LLKR ++ E E++ K +E R+ +++E E+ +QR+ ++++++LEQ Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602 Query: 162 FHAFEEMIRNQELEKERLK 180 E + +E ++RLK Sbjct: 603 KREEVERLEQEERREQRLK 621 Score = 42.4 bits (98), Expect = 8e-04 Identities = 23/97 (23%), Positives = 55/97 (56%), Gaps = 4/97 (4%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE----YNEEKKKEAEELARNMAIQQEL 142 E++D +K+ +E + E K +L + +E E EE+++E +E +++ Sbjct: 453 ERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE 512 Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERL 179 E+ +QR+ +Q++++ Q++ + +++ R QE +E+L Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549 Score = 42.4 bits (98), Expect = 8e-04 Identities = 23/92 (25%), Positives = 55/92 (59%), Gaps = 3/92 (3%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E+++ KL+E + +E + + L+R +E E ++++E E L + + +Q+L +E+ Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 + ++++Q L++E+ E+ R Q L++E+ Sbjct: 543 E---ERREQLLKREEEKRLEQERREQRLKREQ 571 Score = 41.6 bits (96), Expect = 0.001 Identities = 26/109 (23%), Positives = 58/109 (53%), Gaps = 8/109 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLK--EIAFPKAEELKAELLKRYTKEYTEYNEEKKKEA 129 EKL + + + E+++ ++KL+ E+ + EE + + R ++ EE+++E Sbjct: 258 EKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317 Query: 130 EELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 +E R ++E ++E+ ++QQL +EQ E+ +R ++ E+ R Sbjct: 318 QEERREQQERREQQEER------REQQLRREQEERREQQLRREQEEERR 360 Score = 38.9 bits (89), Expect = 0.009 Identities = 22/76 (28%), Positives = 46/76 (60%), Gaps = 3/76 (3%) Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQE-QF 162 EE + + L+R +E E ++ ++E EE R +++E E+E++ +++QQL +E Q Sbjct: 332 EERREQQLRREQEERRE--QQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389 Query: 163 HAFEEMIRNQELEKER 178 +++ R Q+L +E+ Sbjct: 390 RREQQLRREQQLRREQ 405 Score = 38.1 bits (87), Expect = 0.015 Identities = 31/122 (25%), Positives = 60/122 (49%), Gaps = 18/122 (14%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKK-EAE 130 EK + R+ + V E+++ + +E K EE E + +E E E+ +K E + Sbjct: 225 EKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ 284 Query: 131 ELARNMAIQQELEKEKQRVA--------------QQKQQQLEQEQFHAFEEMIRNQELEK 176 EL R +QE E+++QR+ +Q++++ EQ++ +E R Q+L + Sbjct: 285 ELRRE---RQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341 Query: 177 ER 178 E+ Sbjct: 342 EQ 343 Score = 38.1 bits (87), Expect = 0.015 Identities = 18/92 (19%), Positives = 50/92 (54%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E+++ ++ +E + +E + E R +E ++ ++E EE R +++E + + Sbjct: 326 ERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRR 385 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 ++ +++QQ ++Q +++ R Q+L +E+ Sbjct: 386 EQQLRREQQLRREQQLRREQQLRREQQLRREQ 417 Score = 38.1 bits (87), Expect = 0.015 Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 2/100 (2%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQEL-EKE 145 E+ + K +E+ + EE + + LKR E + K E +E R +++E E+ Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655 Query: 146 KQRVAQQKQQQ-LEQEQFHAFEEMIRNQELEKERLKIVQE 184 +QR+ ++++++ LEQ EE R QEL +E + +E Sbjct: 656 EQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695 Score = 38.1 bits (87), Expect = 0.015 Identities = 22/114 (19%), Positives = 62/114 (54%), Gaps = 12/114 (10%) Query: 76 KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEK---------K 126 + R + E+++ ++ +++ + E+ + + L+R +E E +E+ K Sbjct: 1101 RRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEK 1160 Query: 127 KEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 + +EL R ++EL++E++++ +++Q++ QE+ + E +EL++++ K Sbjct: 1161 RRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE---EEELQRQKRK 1211 Score = 37.7 bits (86), Expect = 0.020 Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 2/75 (2%) Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFH 163 EE K Y K + E+ +KE + L Q E+EK+R +Q++Q E+EQ Sbjct: 880 EERKRRRHTLYAKPALQ--EQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937 Query: 164 AFEEMIRNQELEKER 178 EE + +E EK R Sbjct: 938 QEEEQLLREEREKRR 952 Score = 37.7 bits (86), Expect = 0.020 Identities = 28/100 (28%), Positives = 52/100 (52%), Gaps = 5/100 (5%) Query: 84 VIPEKKDTVKKLK-EIAFPKAEELKAE----LLKRYTKEYTEYNEEKKKEAEELARNMAI 138 ++ E+++T ++ + E + K EEL+ E L + K + E + +E EEL + Sbjct: 1063 LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122 Query: 139 QQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 E+EK+R + ++Q E+E+ EE + +E EK R Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162 Score = 37.4 bits (85), Expect = 0.026 Identities = 18/89 (20%), Positives = 49/89 (55%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 +E+L + + + E+ + ++ + + + EE + + L+R +E E ++++E E Sbjct: 607 VERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEE 666 Query: 131 ELARNMAIQQELEKEKQRVAQQKQQQLEQ 159 L + + + E E+ +Q +A+++Q+Q + Sbjct: 667 RLEQRLKREHEEERREQELAEEEQEQARE 695 Score = 37.4 bits (85), Expect = 0.026 Identities = 29/112 (25%), Positives = 56/112 (50%), Gaps = 5/112 (4%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTE--YNEEKKKE 128 +E+ K R + P ++ ++K +++ + EEL+ E ++ ++ E Y EE++ + Sbjct: 878 LEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQ 937 Query: 129 AEE---LARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKE 177 EE L ++ E+E+Q +K QQ E++ E R QE EK+ Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKK 989 Score = 37.0 bits (84), Expect = 0.034 Identities = 27/93 (29%), Positives = 54/93 (58%), Gaps = 14/93 (15%) Query: 96 KEIAFPKAEELKAELLKRYTKEYTEYNEEKKK--------EAEELARNMAIQQELEKEKQ 147 +E + +E + + LKR +E TE +E++++ E E R + +++E +E+Q Sbjct: 443 REQRLKREQEERRDWLKR--EEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500 Query: 148 RVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 ++++QQL +EQ E+ ++ QE E+ERL+ Sbjct: 501 ---ERREQQLRREQEERREQRLKRQE-EEERLQ 529 Score = 36.6 bits (83), Expect = 0.044 Identities = 16/86 (18%), Positives = 49/86 (56%) Query: 93 KKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQ 152 +K +E + EE + + +R +E + ++++ E + + +QE E+ +Q++ ++ Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367 Query: 153 KQQQLEQEQFHAFEEMIRNQELEKER 178 ++++ ++Q +++ R Q+L +E+ Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQ 393 Score = 36.6 bits (83), Expect = 0.044 Identities = 26/94 (27%), Positives = 49/94 (52%), Gaps = 4/94 (4%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E++ +K K++ + + L E KR +E E+K +E EEL + E+EK Sbjct: 955 ERERQYRKDKKLQQKEEQLLGEEPEKRRRQE----REKKYREEEELQQEEEQLLREEREK 1010 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 +R + ++Q ++++ EE + +E EK RL+ Sbjct: 1011 RRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044 Score = 36.6 bits (83), Expect = 0.044 Identities = 25/98 (25%), Positives = 54/98 (55%), Gaps = 4/98 (4%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEY---NEEKKKEAEELARNMAIQQELE 143 E++ ++ +E+ + + L+ E KR +E+ +E ++E E+L R ++ L+ Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ 1044 Query: 144 KEKQRVAQQKQQQLEQEQFHAFE-EMIRNQELEKERLK 180 + +++ ++++ Q E+EQ E E R QELE++ K Sbjct: 1045 ERERQYREEEELQQEEEQLLGEERETRRRQELERQYRK 1082 Score = 36.6 bits (83), Expect = 0.044 Identities = 26/86 (30%), Positives = 48/86 (55%), Gaps = 5/86 (5%) Query: 100 FPKAEELKAELLKRYTKEYTEYNEEK---KKEAEELARNMAIQQELEKEKQRVAQQKQQQ 156 FP+ E+L+ E K + + EEK ++E EE R ++ +E+Q + ++++Q Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352 Query: 157 L-EQEQFHAF-EEMIRNQELEKERLK 180 L QE+ F EE +R+QE ++ L+ Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLE 1378 Score = 36.6 bits (83), Expect = 0.044 Identities = 32/125 (25%), Positives = 62/125 (49%), Gaps = 10/125 (8%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAEL-------LKRYTKEYTEYNEE 124 E+ + ++ + + E++ ++ E F + E+L+ E +RY K E Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756 Query: 125 KKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAF--EEMIRNQELEKERLKIV 182 ++E ++L R ++ E+E+ R +++QQ QE F EE +R QE E+++L+ Sbjct: 1757 PEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLR-QEREEQQLRPQ 1815 Query: 183 QEFGK 187 Q GK Sbjct: 1816 QRDGK 1820 Score = 36.2 bits (82), Expect = 0.058 Identities = 17/86 (19%), Positives = 50/86 (58%), Gaps = 2/86 (2%) Query: 93 KKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQ 152 ++ +++ + EE + + L+R +E E E++ + ++L R +++E + +++ ++ Sbjct: 346 RREQQLRREQEEERREQQLRREQEE--ERREQQLRREQQLRREQQLRREQQLRREQQLRR 403 Query: 153 KQQQLEQEQFHAFEEMIRNQELEKER 178 +QQ ++Q +++ R Q+L +E+ Sbjct: 404 EQQLRREQQLRREQQLRREQQLRREQ 429 Score = 35.8 bits (81), Expect = 0.076 Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 7/127 (5%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIA----FPKAEELKAELLKRYTKEYTEYNEEKKK 127 E+L K + K ++ +K+ +E + EE + + LKR +E E K++ Sbjct: 547 EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLE-QRLKRE 605 Query: 128 EAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRN--QELEKERLKIVQEF 185 E E L + +Q L++E+ +++Q +EQ ++ +R QE ++RLK +E Sbjct: 606 EVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEE 665 Query: 186 GKVDPGL 192 +++ L Sbjct: 666 ERLEQRL 672 Score = 34.7 bits (78), Expect = 0.17 Identities = 28/88 (31%), Positives = 46/88 (52%), Gaps = 6/88 (6%) Query: 96 KEIAFPKAEELKAE---LL--KRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVA 150 +E + + EEL+ E LL +R T+ E + +KE EEL + E EK+R Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKE-EELQQEEEQLLREEPEKRRRQ 1104 Query: 151 QQKQQQLEQEQFHAFEEMIRNQELEKER 178 ++++Q E+E+ EE + +E EK R Sbjct: 1105 ERERQCREEEELQQEEEQLLREEREKRR 1132 Score = 34.3 bits (77), Expect = 0.22 Identities = 23/90 (25%), Positives = 45/90 (50%), Gaps = 2/90 (2%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147 KKD +++ +E EE + L+ ++Y E E +++E + L ++ E E+Q Sbjct: 1022 KKDELQQEEEQLL--REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079 Query: 148 RVAQQKQQQLEQEQFHAFEEMIRNQELEKE 177 +++ QQ E++ E R QE E++ Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQ 1109 Score = 33.9 bits (76), Expect = 0.29 Identities = 19/77 (24%), Positives = 40/77 (51%) Query: 102 KAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161 + +L+AE ++ + + EEK++ + Q LE+E+Q +++ QQL++E+ Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853 Query: 162 FHAFEEMIRNQELEKER 178 E+ R + E+ R Sbjct: 854 DGLQEDQERRRSQEQRR 870 Score = 33.9 bits (76), Expect = 0.29 Identities = 20/78 (25%), Positives = 46/78 (58%), Gaps = 5/78 (6%) Query: 105 ELKAELLKRYTKEYTEYNEEKK-KEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-- 161 E + +L ++ ++ ++ ++K +E E+L + QQ +E+ R ++++QQL +++ Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERE 1706 Query: 162 --FHAFEEMIRNQELEKE 177 F E+ +R QELE++ Sbjct: 1707 RKFLQEEQQLRRQELERK 1724 Score = 33.9 bits (76), Expect = 0.29 Identities = 22/79 (27%), Positives = 44/79 (55%), Gaps = 7/79 (8%) Query: 113 RYTKEYTEYNEEKKKEAEELARN------MAIQQELEKEKQRVAQQKQQQLEQEQFHAF- 165 R+ +E + E++++ +E R A Q++ +E+Q + Q+++Q+ QE+ Sbjct: 1822 RWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLR 1881 Query: 166 EEMIRNQELEKERLKIVQE 184 EE IR Q+ E++R + V E Sbjct: 1882 EEHIRRQQKEEQRHRQVGE 1900 Score = 33.5 bits (75), Expect = 0.38 Identities = 31/125 (24%), Positives = 63/125 (50%), Gaps = 21/125 (16%) Query: 72 EKLPKHRDYKSA----VIPEKKDTVKKLKEI--AFPKAEEL----------KAELLKRYT 115 +K K RD KS ++ E+++ ++ +E F + E+L + E +++ Sbjct: 1304 QKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFR 1363 Query: 116 KEYTEYNEEKKKEAEELARNMAIQQE---LEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQ 172 +E + E+ +K EE R ++E L++E+Q Q+++QQL Q++ F E Q Sbjct: 1364 EEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFRE--EEQ 1421 Query: 173 ELEKE 177 +L ++ Sbjct: 1422 QLSRQ 1426 Score = 33.1 bits (74), Expect = 0.49 Identities = 20/85 (23%), Positives = 45/85 (52%), Gaps = 4/85 (4%) Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-- 161 +E + L+ + + E K + E+ R +Q+L +++ R ++++QQL +++ Sbjct: 1370 QEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429 Query: 162 --FHAFEEMIRNQELEKERLKIVQE 184 F E+ +R QE E++ L+ Q+ Sbjct: 1430 RKFREEEQQVRRQERERKFLEEEQQ 1454 Score = 33.1 bits (74), Expect = 0.49 Identities = 23/88 (26%), Positives = 46/88 (52%), Gaps = 1/88 (1%) Query: 93 KKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQ 152 K LKE + +E + +L + +++ E ++ ++ + QQ +E++R + Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450 Query: 153 KQQQLEQEQFHAF-EEMIRNQELEKERL 179 ++QQL QE+ F EE QE E+++L Sbjct: 1451 EEQQLRQERHRKFREEEQLLQEREEQQL 1478 Score = 32.3 bits (72), Expect = 0.84 Identities = 28/118 (23%), Positives = 62/118 (52%), Gaps = 5/118 (4%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEE---KKKE 128 ++L + RD K ++ ++ ++ + + + E +++ +E + +E K +E Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFRE 1465 Query: 129 AEELARNMAIQQELEKEKQRVAQQKQQQL-EQEQFHAF-EEMIRNQELEKERLKIVQE 184 E+L + QQ +E+ R +++QQL QE+ F E+ +R+QE E++ L+ Q+ Sbjct: 1466 EEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQ 1523 Score = 32.0 bits (71), Expect = 1.1 Identities = 24/97 (24%), Positives = 51/97 (52%), Gaps = 16/97 (16%) Query: 100 FPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKE---KQRVAQQKQQQ 156 FP E+L+ L ++ E +++++E ++ Q+E EKE ++ V ++++++ Sbjct: 204 FPDEEQLRRRELLELRRKGREEKQQQRRERQD----RVFQEEEEKEWRKRETVLRKEEEK 259 Query: 157 LEQE------QFHAFEEMIR---NQELEKERLKIVQE 184 L++E + EE +R QEL +ER + Q+ Sbjct: 260 LQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296 Score = 31.6 bits (70), Expect = 1.4 Identities = 20/85 (23%), Positives = 48/85 (56%), Gaps = 4/85 (4%) Query: 104 EELKAELLKRYTKEYTEY--NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161 +E + + LKR +E ++ EE+ + E+ R ++++ E+E++ + +++ +EQ Sbjct: 440 QERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQ 499 Query: 162 FHAFEEMIRNQELEK--ERLKIVQE 184 E+ +R ++ E+ +RLK +E Sbjct: 500 QERREQQLRREQEERREQRLKRQEE 524 Score = 31.6 bits (70), Expect = 1.4 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 4/86 (4%) Query: 97 EIAFPKAEELKAE----LLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQ 152 E + K +EL+ E L + K + E + +E EEL + E+E +R + Sbjct: 1017 ERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQEL 1076 Query: 153 KQQQLEQEQFHAFEEMIRNQELEKER 178 ++Q ++E+ EE + +E EK R Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRR 1102 Score = 31.6 bits (70), Expect = 1.4 Identities = 23/106 (21%), Positives = 53/106 (50%), Gaps = 19/106 (17%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQ------ 140 E++ ++ ++ F + E+L+ E ++ + ++ ++ K +E E+L + QQ Sbjct: 1760 EEQQLRRQERDRKFREEEQLRQEREEQQLR--SQESDRKFREEEQLRQEREEQQLRPQQR 1817 Query: 141 -----------ELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELE 175 +LE+++QR+ Q++ +Q E+ A +E R +E E Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863 Score = 30.8 bits (68), Expect = 2.4 Identities = 22/101 (21%), Positives = 55/101 (54%), Gaps = 6/101 (5%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAI--QQELEKE 145 +++ ++ +E + ++L+ E ++ +E E++ + ++L R + +Q+L +E Sbjct: 365 RREQEEERREQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422 Query: 146 KQRVAQQKQQQLEQ--EQFHAFEEMIRNQELEKERLKIVQE 184 +Q +Q++++ EQ EQ + + R QE ++ LK +E Sbjct: 423 QQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEE 463 Score = 30.8 bits (68), Expect = 2.4 Identities = 24/98 (24%), Positives = 50/98 (51%), Gaps = 4/98 (4%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYT-EYNEEKK---KEAEELARNMAIQQEL 142 E++ ++ +++ + + L+ E KR +E +Y ++KK KE + L ++ Sbjct: 925 EQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQ 984 Query: 143 EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 E+EK+ +++ QQ E++ E R QE E++ K Sbjct: 985 EREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK 1022 Score = 30.8 bits (68), Expect = 2.4 Identities = 20/79 (25%), Positives = 40/79 (50%), Gaps = 4/79 (5%) Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-- 161 +E + + L R ++ EE++ +E R Q+ +E +R +++QQL ++Q Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQ 1530 Query: 162 --FHAFEEMIRNQELEKER 178 F E+ +R QE ++R Sbjct: 1531 RKFLQEEQQLRRQERGQQR 1549 Score = 30.4 bits (67), Expect = 3.2 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 8/75 (10%) Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFH 163 +E + + L R ++ EE+K +E R +E E+Q Q+ QQQL QE+ Sbjct: 1565 QEREEQQLSRQERDRKFRLEEQKVRRQEQERKF-----MEDEQQLRRQEGQQQLRQERDR 1619 Query: 164 AFEEMIRNQELEKER 178 F E +++L +ER Sbjct: 1620 KFRE---DEQLLQER 1631 Score = 30.4 bits (67), Expect = 3.2 Identities = 23/102 (22%), Positives = 53/102 (51%), Gaps = 5/102 (4%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 +++D + E + EE + +R K E + +++E E+ R+ ++ +E+ Sbjct: 1615 QERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR-DRKFREEE 1673 Query: 147 QRVAQQKQQQLEQEQ----FHAFEEMIRNQELEKERLKIVQE 184 Q + + ++QQL +++ F E+ +R QE E++ L+ Q+ Sbjct: 1674 QLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQ 1715 Score = 30.0 bits (66), Expect = 4.1 Identities = 28/117 (23%), Positives = 54/117 (46%), Gaps = 18/117 (15%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E+L + + PEK+ ++ ++ + EEL+ E ++ EK++ +E Sbjct: 1084 EELQQEEEQLLREEPEKRRRQERERQCR--EEEELQQE-----EEQLLREEREKRRR-QE 1135 Query: 132 LARNMAIQQEL----------EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 L R ++E+ E EK+R + ++Q E+E+ EE + +E EK R Sbjct: 1136 LERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRR 1192 Score = 30.0 bits (66), Expect = 4.1 Identities = 12/56 (21%), Positives = 37/56 (66%), Gaps = 5/56 (8%) Query: 123 EEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 E++++ ++ R+ +++LE+E+Q+ A+++ ++ ++E+ +++R + EK R Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEK-----QLLREEREEKRR 1330 Score = 29.6 bits (65), Expect = 5.4 Identities = 26/119 (21%), Positives = 63/119 (52%), Gaps = 14/119 (11%) Query: 70 FIEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEA 129 F+E+ P+ R E++ ++ ++ F + E+L E ++ + + + K +E Sbjct: 1645 FLEEEPQLRRQ------EREQQLRHDRDRKFREEEQLLQEGEEQQLRR--QERDRKFREE 1696 Query: 130 EELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188 E+ R +++ +E+Q++ +Q+ ++ +E EE +R QE E+E+L+ + + K+ Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFRE-----EEQLR-QETEQEQLRRQERYRKI 1749 Score = 29.3 bits (64), Expect = 7.1 Identities = 22/99 (22%), Positives = 53/99 (53%), Gaps = 12/99 (12%) Query: 96 KEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK---QRVAQQ 152 +E + ++L+ E ++ +E E++ + ++L R +++E E+E+ + ++ Sbjct: 385 REQQLRREQQLRRE--QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQER 442 Query: 153 KQQQLEQEQFHAFEEMIRNQELE-------KERLKIVQE 184 ++Q+L++EQ + + R +E E K++LK QE Sbjct: 443 REQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQE 481 Score = 29.3 bits (64), Expect = 7.1 Identities = 21/84 (25%), Positives = 43/84 (51%), Gaps = 3/84 (3%) Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQE--- 160 EE + +R K E + +++E + R ++ E+E+ R +++QQ QE Sbjct: 1520 EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDR 1579 Query: 161 QFHAFEEMIRNQELEKERLKIVQE 184 +F E+ +R QE E++ ++ Q+ Sbjct: 1580 KFRLEEQKVRRQEQERKFMEDEQQ 1603 Score = 28.9 bits (63), Expect = 9.2 Identities = 25/102 (24%), Positives = 48/102 (47%), Gaps = 8/102 (7%) Query: 76 KHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARN 135 + R Y+ +KK K+ + + + + E K+Y +E EE++ EE + Sbjct: 956 RERQYRK----DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKR 1011 Query: 136 MAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKE 177 + E + K+ QQ+++QL +E+ E R QE E++ Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREE----REKRRLQERERQ 1049 Score = 28.9 bits (63), Expect = 9.2 Identities = 25/106 (23%), Positives = 56/106 (52%), Gaps = 5/106 (4%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEE---LKAELLKRYTKEYTEYNEEK-KK 127 E+L + R+ + + P+++D + +E E+ L+ E ++Y E +EK ++ Sbjct: 1801 EQLRQERE-EQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRR 1859 Query: 128 EAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQE 173 E +EL + ++ E+E++ + ++Q ++EQ H I++QE Sbjct: 1860 EEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQE 1905 >gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo sapiens] Length = 482 Score = 42.7 bits (99), Expect = 6e-04 Identities = 30/117 (25%), Positives = 62/117 (52%), Gaps = 9/117 (7%) Query: 70 FIEKLPKHRDYKSAVIPEKK----DTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEK 125 F EK P H+ Y++A+ EK+ + +L++ + EE + ++ E + E + Sbjct: 9 FPEK-PSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERE 67 Query: 126 KKEAEE--LARNMAIQQE--LEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 ++ E L R Q+E ++KEK+ A+++Q++ E++ +EE R + E+E+ Sbjct: 68 RQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124 Score = 32.7 bits (73), Expect = 0.64 Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 6/67 (8%) Query: 92 VKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQ 151 +KK KE A K +E + LK ++ E+++KE EE + ++E E+ Q++ Sbjct: 88 IKKEKEEAAKKRQEEQERKLKE------QWEEQQRKEREEEEQKRQEKKEKEEALQKMLD 141 Query: 152 QKQQQLE 158 Q + +LE Sbjct: 142 QAENELE 148 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 41.2 bits (95), Expect = 0.002 Identities = 29/102 (28%), Positives = 59/102 (57%), Gaps = 10/102 (9%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE--- 143 EK++ +++ +E+ + K E+++ K + +E EEK++E EE R +QE E Sbjct: 421 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE-EEKIREQEKRQEQEAKM 479 Query: 144 -KEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 ++++++ +Q+++ EQE E+M R +E E+ KI +E Sbjct: 480 WRQEEKIREQEEKIREQE-----EKMWRQEEKIHEQEKIREE 516 Score = 40.4 bits (93), Expect = 0.003 Identities = 22/87 (25%), Positives = 50/87 (57%), Gaps = 3/87 (3%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 EK++ +++ +E+ + K E+++ + + KE E+K +E R Q+E +E+ Sbjct: 407 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE---QEEKRQEE 463 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE 173 +++ +Q+++Q ++ + EE IR QE Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQE 490 Score = 38.9 bits (89), Expect = 0.009 Identities = 34/123 (27%), Positives = 65/123 (52%), Gaps = 6/123 (4%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKA-ELLKRYTKEYTEYNEEKK-KEA 129 E++ ++ K + EK +K++E + EE K E KR +E + +E+K +E Sbjct: 430 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 489 Query: 130 EELARNMAIQQELEKEK---QRVAQQKQQQLEQEQFHAFEEMIRNQ-ELEKERLKIVQEF 185 EE R + ++EK Q ++++++ EQE+ EE IR Q E+ +++ KI ++ Sbjct: 490 EEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549 Query: 186 GKV 188 K+ Sbjct: 550 EKI 552 Score = 36.6 bits (83), Expect = 0.044 Identities = 25/95 (26%), Positives = 54/95 (56%), Gaps = 9/95 (9%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKA-----ELLKRYTKEYTEYNEEKKKEAEELARNMAIQ 139 I E+++ +++ +E + + E++ E KR +E EEK +E EE+ R + Sbjct: 486 IREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQ---K 542 Query: 140 QELEKEKQRVAQQKQQQLEQEQ-FHAFEEMIRNQE 173 +++ ++++++ +Q+++ QE+ H EE IR QE Sbjct: 543 EKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQE 577 Score = 35.4 bits (80), Expect = 0.099 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 19/158 (12%) Query: 43 IIRMASIYSEEGNIEHAF---ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIA 99 I R+ + G +E A K +IE+L K RD S + T ++LKE Sbjct: 225 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 284 Query: 100 FPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE-------KEKQRVAQQ 152 E+L+ L K + N ++ K E A+ + QQ+L+ KE Q V+ + Sbjct: 285 AKLQEKLQ---LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 341 Query: 153 KQQQLEQEQF------HAFEEMIRNQELEKERLKIVQE 184 Q Q+E+ + E+M R +E +E + +QE Sbjct: 342 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 379 Score = 34.7 bits (78), Expect = 0.17 Identities = 28/92 (30%), Positives = 54/92 (58%), Gaps = 6/92 (6%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQE-L 142 I E+++ V + +E + E+++ + K R +E T+ EEK E EE M Q+E + Sbjct: 573 IREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE---KMCEQEEKM 629 Query: 143 EKEKQRVAQQKQQQLEQE-QFHAFEEMIRNQE 173 +++++++ +Q+++ EQE + EE IR QE Sbjct: 630 QEQEEKMRRQEEKIREQEKKIREQEEKIREQE 661 Score = 34.3 bits (77), Expect = 0.22 Identities = 20/98 (20%), Positives = 58/98 (59%), Gaps = 13/98 (13%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 ++++ +++ +E + + E+++ + +E EEK +E EE+ + ++++ +++ Sbjct: 568 DQEEKIREQEEKVWRQEEKIREQ------EEKIREQEEKIREQEEMTQEQ--EEKMGEQE 619 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 +++ +Q+++ EQE E+M R +E +E+ K ++E Sbjct: 620 EKMCEQEEKMQEQE-----EKMRRQEEKIREQEKKIRE 652 Score = 32.7 bits (73), Expect = 0.64 Identities = 21/95 (22%), Positives = 49/95 (51%), Gaps = 1/95 (1%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYT-EYNEEKKKEAEELARNMAIQQELE 143 I E+++ +++ +E+ + E++ + K +E + EEK + EE R + + Sbjct: 594 IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQ 653 Query: 144 KEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKER 178 +EK R ++ Q+ E++ + E+M +E +E+ Sbjct: 654 EEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 688 Score = 30.4 bits (67), Expect = 3.2 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 6/82 (7%) Query: 113 RYTKEYTEYNEEKKKEAEEL----ARNMAIQQEL--EKEKQRVAQQKQQQLEQEQFHAFE 166 R +E EEK + EE+ M Q+E+ EKE++ Q++ ++E+ E Sbjct: 385 REQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444 Query: 167 EMIRNQELEKERLKIVQEFGKV 188 E + QE +E+ + QE K+ Sbjct: 445 EKMHEQEKIREQEEKRQEEEKI 466 Score = 30.4 bits (67), Expect = 3.2 Identities = 16/71 (22%), Positives = 41/71 (57%), Gaps = 1/71 (1%) Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ-F 162 EE E ++ ++ + E++KK E+ + ++ ++++++++ +Q+++ EQE+ Sbjct: 626 EEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 685 Query: 163 HAFEEMIRNQE 173 EE +R QE Sbjct: 686 QEQEEKMRRQE 696 Score = 30.0 bits (66), Expect = 4.1 Identities = 17/90 (18%), Positives = 52/90 (57%), Gaps = 3/90 (3%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK-KEAEELARNMAIQQELEKEK 146 +++ + + KE + E+++ + K + +E +++E+K +E EE ++++ +++ Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ--EEKIREQE 591 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQELEK 176 +++ +Q+++ EQE+ +E ++ EK Sbjct: 592 EKIREQEEKIREQEEMTQEQEEKMGEQEEK 621 Score = 29.6 bits (65), Expect = 5.4 Identities = 31/130 (23%), Positives = 64/130 (49%), Gaps = 12/130 (9%) Query: 67 ITLFIEKLPKHRDYKSAVIPEKKDTV------KKLKEIAFP-KAEELKAELLKRYTKEYT 119 I L +++L + + ++P+++ K+L+ ++ +A+ + EL R ++ Sbjct: 301 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 360 Query: 120 EY---NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQEL-- 174 E EEK +E EE + + ++EK R ++K ++ E+ + E+M R +E+ Sbjct: 361 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420 Query: 175 EKERLKIVQE 184 EKE QE Sbjct: 421 EKEEKMRRQE 430 Score = 29.6 bits (65), Expect = 5.4 Identities = 21/87 (24%), Positives = 48/87 (55%), Gaps = 3/87 (3%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147 +++ +++ +EI K + + E R +E EEK + EE R ++++ ++++ Sbjct: 528 QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ--EEKVWRQEE 585 Query: 148 RVAQQKQQQLEQEQ-FHAFEEMIRNQE 173 ++ +Q+++ EQE+ EEM + QE Sbjct: 586 KIREQEEKIREQEEKIREQEEMTQEQE 612 Score = 29.6 bits (65), Expect = 5.4 Identities = 21/80 (26%), Positives = 45/80 (56%), Gaps = 6/80 (7%) Query: 109 ELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEM 168 E ++ K+ E EEK +E EE+ + ++ E+E++ Q+++ Q ++E+ EE Sbjct: 641 EKIREQEKKIRE-QEEKIREQEEMMQEQE-EKMWEQEEKMCEQEEKMQEQEEKMRRQEEK 698 Query: 169 IRNQEL----EKERLKIVQE 184 + QE+ ++E+++ QE Sbjct: 699 MWEQEVRLRQQEEKMQEHQE 718 >gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo sapiens] Length = 1972 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 10/101 (9%) Query: 88 KKDTVKKLKEIAFPKAEELKAEL-LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 K+D ++K KE + KAE LK +++++ EEK E+L + E E+ + Sbjct: 857 KEDELQKTKE------RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910 Query: 147 QRVAQQKQQQ---LEQEQFHAFEEMIRNQELEKERLKIVQE 184 R+A +KQ+ L + + EE R Q+L+ ER K+ Q+ Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951 Score = 36.6 bits (83), Expect = 0.044 Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNE------EK 125 ++L K ++ + E K+ +K ++ K L E L+ T+ Y E E K Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEEK--NLLQEQLQAETELYAEAEEMRVRLAAK 916 Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181 K+E EE+ M + E E+++ + Q +++++ Q+ EE + +E +++L++ Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD-LEEQLEEEEAARQKLQL 971 Score = 34.7 bits (78), Expect = 0.17 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 +E RD A E + K L+ E+L A R + EK++ AE Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL-----EKEELAE 1715 Query: 131 ELARNMAIQQELEKEKQRV---AQQKQQQLEQEQ--FHAFEEMIRNQELEKERL 179 ELA +++ + L+ EK+R+ Q +++LE+EQ A + +R + E+L Sbjct: 1716 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769 Score = 33.1 bits (74), Expect = 0.49 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E++ + K A K KKLKEI L+ E ++ ++Y E E+ ++ Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEIL------LQVEDERKMAEQYKEQAEKGNARVKQ 1881 Query: 132 LARNMAIQQELEKEKQRV--AQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 L R + +E E+E QR+ ++K Q+ E + E M R K +L+ Sbjct: 1882 LKRQL---EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929 Score = 29.3 bits (64), Expect = 7.1 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 117 EYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLE-----QEQFHAFEEMIRN 171 + T EE + + +EL + QQ+ E E + + Q+ Q E QEQ A E+ Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905 Query: 172 QELEKERL 179 E + RL Sbjct: 906 AEEMRVRL 913 >gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo sapiens] Length = 1979 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 10/101 (9%) Query: 88 KKDTVKKLKEIAFPKAEELKAEL-LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 K+D ++K KE + KAE LK +++++ EEK E+L + E E+ + Sbjct: 864 KEDELQKTKE------RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917 Query: 147 QRVAQQKQQQ---LEQEQFHAFEEMIRNQELEKERLKIVQE 184 R+A +KQ+ L + + EE R Q+L+ ER K+ Q+ Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958 Score = 36.6 bits (83), Expect = 0.044 Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNE------EK 125 ++L K ++ + E K+ +K ++ K L E L+ T+ Y E E K Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEEK--NLLQEQLQAETELYAEAEEMRVRLAAK 923 Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181 K+E EE+ M + E E+++ + Q +++++ Q+ EE + +E +++L++ Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD-LEEQLEEEEAARQKLQL 978 Score = 34.7 bits (78), Expect = 0.17 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 +E RD A E + K L+ E+L A R + EK++ AE Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL-----EKEELAE 1722 Query: 131 ELARNMAIQQELEKEKQRV---AQQKQQQLEQEQ--FHAFEEMIRNQELEKERL 179 ELA +++ + L+ EK+R+ Q +++LE+EQ A + +R + E+L Sbjct: 1723 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1776 Score = 33.1 bits (74), Expect = 0.49 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E++ + K A K KKLKEI L+ E ++ ++Y E E+ ++ Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEIL------LQVEDERKMAEQYKEQAEKGNARVKQ 1888 Query: 132 LARNMAIQQELEKEKQRV--AQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 L R + +E E+E QR+ ++K Q+ E + E M R K +L+ Sbjct: 1889 LKRQL---EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936 Score = 29.3 bits (64), Expect = 7.1 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 117 EYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLE-----QEQFHAFEEMIRN 171 + T EE + + +EL + QQ+ E E + + Q+ Q E QEQ A E+ Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912 Query: 172 QELEKERL 179 E + RL Sbjct: 913 AEEMRVRL 920 >gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo sapiens] Length = 1945 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 10/101 (9%) Query: 88 KKDTVKKLKEIAFPKAEELKAEL-LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 K+D ++K KE + KAE LK +++++ EEK E+L + E E+ + Sbjct: 864 KEDELQKTKE------RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 917 Query: 147 QRVAQQKQQQ---LEQEQFHAFEEMIRNQELEKERLKIVQE 184 R+A +KQ+ L + + EE R Q+L+ ER K+ Q+ Sbjct: 918 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958 Score = 36.6 bits (83), Expect = 0.044 Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNE------EK 125 ++L K ++ + E K+ +K ++ K L E L+ T+ Y E E K Sbjct: 866 DELQKTKERQQKAENELKELEQKHSQLTEEK--NLLQEQLQAETELYAEAEEMRVRLAAK 923 Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181 K+E EE+ M + E E+++ + Q +++++ Q+ EE + +E +++L++ Sbjct: 924 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD-LEEQLEEEEAARQKLQL 978 Score = 34.7 bits (78), Expect = 0.17 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 +E RD A E + K L+ E+L A R + EK++ AE Sbjct: 1668 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL-----EKEELAE 1722 Query: 131 ELARNMAIQQELEKEKQRV---AQQKQQQLEQEQ--FHAFEEMIRNQELEKERL 179 ELA +++ + L+ EK+R+ Q +++LE+EQ A + +R + E+L Sbjct: 1723 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1776 Score = 33.1 bits (74), Expect = 0.49 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E++ + K A K KKLKEI L+ E ++ ++Y E E+ ++ Sbjct: 1835 EQVEQEAREKQAATKSLKQKDKKLKEIL------LQVEDERKMAEQYKEQAEKGNARVKQ 1888 Query: 132 LARNMAIQQELEKEKQRV--AQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 L R + +E E+E QR+ ++K Q+ E + E M R K +L+ Sbjct: 1889 LKRQL---EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936 Score = 29.3 bits (64), Expect = 7.1 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 117 EYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLE-----QEQFHAFEEMIRN 171 + T EE + + +EL + QQ+ E E + + Q+ Q E QEQ A E+ Sbjct: 853 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 912 Query: 172 QELEKERL 179 E + RL Sbjct: 913 AEEMRVRL 920 >gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo sapiens] Length = 1938 Score = 41.2 bits (95), Expect = 0.002 Identities = 31/101 (30%), Positives = 53/101 (52%), Gaps = 10/101 (9%) Query: 88 KKDTVKKLKEIAFPKAEELKAEL-LKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 K+D ++K KE + KAE LK +++++ EEK E+L + E E+ + Sbjct: 857 KEDELQKTKE------RQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMR 910 Query: 147 QRVAQQKQQQ---LEQEQFHAFEEMIRNQELEKERLKIVQE 184 R+A +KQ+ L + + EE R Q+L+ ER K+ Q+ Sbjct: 911 VRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951 Score = 36.6 bits (83), Expect = 0.044 Identities = 27/116 (23%), Positives = 58/116 (50%), Gaps = 9/116 (7%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNE------EK 125 ++L K ++ + E K+ +K ++ K L E L+ T+ Y E E K Sbjct: 859 DELQKTKERQQKAENELKELEQKHSQLTEEK--NLLQEQLQAETELYAEAEEMRVRLAAK 916 Query: 126 KKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKI 181 K+E EE+ M + E E+++ + Q +++++ Q+ EE + +E +++L++ Sbjct: 917 KQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD-LEEQLEEEEAARQKLQL 971 Score = 34.7 bits (78), Expect = 0.17 Identities = 31/114 (27%), Positives = 53/114 (46%), Gaps = 10/114 (8%) Query: 71 IEKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAE 130 +E RD A E + K L+ E+L A R + EK++ AE Sbjct: 1661 LEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADL-----EKEELAE 1715 Query: 131 ELARNMAIQQELEKEKQRV---AQQKQQQLEQEQ--FHAFEEMIRNQELEKERL 179 ELA +++ + L+ EK+R+ Q +++LE+EQ A + +R + E+L Sbjct: 1716 ELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQL 1769 Score = 33.1 bits (74), Expect = 0.49 Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 11/111 (9%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEE 131 E++ + K A K KKLKEI L+ E ++ ++Y E E+ ++ Sbjct: 1828 EQVEQEAREKQAATKSLKQKDKKLKEIL------LQVEDERKMAEQYKEQAEKGNARVKQ 1881 Query: 132 LARNMAIQQELEKEKQRV--AQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 L R + +E E+E QR+ ++K Q+ E + E M R K +L+ Sbjct: 1882 LKRQL---EEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929 Score = 29.3 bits (64), Expect = 7.1 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 117 EYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLE-----QEQFHAFEEMIRN 171 + T EE + + +EL + QQ+ E E + + Q+ Q E QEQ A E+ Sbjct: 846 QVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAE 905 Query: 172 QELEKERL 179 E + RL Sbjct: 906 AEEMRVRL 913 >gi|32967605 bromodomain adjacent to zinc finger domain, 1A isoform b [Homo sapiens] Length = 1524 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/105 (24%), Positives = 60/105 (57%), Gaps = 5/105 (4%) Query: 80 YKSAVIPEKKDTVKK--LKEIAFPKAE--ELKAELLKRYTKEYTEYNEEKKKEAEELARN 135 Y+S E+ +K+ +K +AF KA+ KA+ L+ KE E E+K++E +++ Sbjct: 300 YRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKE-KEDKEKKREELKKIVEE 358 Query: 136 MAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 ++++ EKE+ +V ++K+++ +E+ + E ++ +E ++ Sbjct: 359 ERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDME 403 Score = 29.6 bits (65), Expect = 5.4 Identities = 15/55 (27%), Positives = 38/55 (69%), Gaps = 2/55 (3%) Query: 109 ELLKRYTKEYTEYN-EEKKKEAEELARNMAIQQELE-KEKQRVAQQKQQQLEQEQ 161 ++L++ +E+ E E+ +KE EE A + ++E + KE+++ ++KQ++L++++ Sbjct: 607 DILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDE 661 >gi|32967603 bromodomain adjacent to zinc finger domain, 1A isoform a [Homo sapiens] Length = 1556 Score = 41.2 bits (95), Expect = 0.002 Identities = 26/105 (24%), Positives = 60/105 (57%), Gaps = 5/105 (4%) Query: 80 YKSAVIPEKKDTVKK--LKEIAFPKAE--ELKAELLKRYTKEYTEYNEEKKKEAEELARN 135 Y+S E+ +K+ +K +AF KA+ KA+ L+ KE E E+K++E +++ Sbjct: 300 YRSKATKERDKLLKQEEMKSLAFEKAKLKREKADALEAKKKE-KEDKEKKREELKKIVEE 358 Query: 136 MAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLK 180 ++++ EKE+ +V ++K+++ +E+ + E ++ +E ++ Sbjct: 359 ERLKKKEEKERLKVEREKEREKLREEKRKYVEYLKQWSKPREDME 403 Score = 29.6 bits (65), Expect = 5.4 Identities = 15/55 (27%), Positives = 38/55 (69%), Gaps = 2/55 (3%) Query: 109 ELLKRYTKEYTEYN-EEKKKEAEELARNMAIQQELE-KEKQRVAQQKQQQLEQEQ 161 ++L++ +E+ E E+ +KE EE A + ++E + KE+++ ++KQ++L++++ Sbjct: 639 DILRQAKQEFRELKAEQHRKEREEAAARIRKRKEEKLKEQEQKMKEKQEKLKEDE 693 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 40.8 bits (94), Expect = 0.002 Identities = 22/112 (19%), Positives = 64/112 (57%), Gaps = 10/112 (8%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEEL----------ARNM 136 EK++ +++ +E+ + K E+++ K + +E EEK++E E++ A+ Sbjct: 374 EKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMW 433 Query: 137 AIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188 ++++ ++++++ +Q+++ QE+ +E IR +E +E+ ++ ++ K+ Sbjct: 434 RQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKI 485 Score = 40.4 bits (93), Expect = 0.003 Identities = 22/87 (25%), Positives = 50/87 (57%), Gaps = 3/87 (3%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 EK++ +++ +E+ + K E+++ + + KE E+K +E R Q+E +E+ Sbjct: 360 EKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE---QEEKRQEE 416 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQE 173 +++ +Q+++Q ++ + EE IR QE Sbjct: 417 EKIREQEKRQEQEAKMWRQEEKIREQE 443 Score = 37.4 bits (85), Expect = 0.026 Identities = 23/88 (26%), Positives = 53/88 (60%), Gaps = 5/88 (5%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145 E+++ ++K +E + + E+++ + K R +E EEK +E EE+ R ++E E Sbjct: 500 EQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR----EEEKMHE 555 Query: 146 KQRVAQQKQQQLEQEQFHAFEEMIRNQE 173 ++++ +++++Q ++++ EE IR QE Sbjct: 556 QEKIWEEEKRQEQEDKMWRQEEKIREQE 583 Score = 36.2 bits (82), Expect = 0.058 Identities = 39/130 (30%), Positives = 68/130 (52%), Gaps = 13/130 (10%) Query: 72 EKLPKHRDYKSAVIPEKKDTVKKLKEIAFPKAEELKA-ELLKRYTKEYTEYNEEKK-KEA 129 E++ ++ K + EK +K++E + EE K E KR +E + +E+K +E Sbjct: 383 EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQ 442 Query: 130 EELARN----MAIQQEL--EKEKQRVAQQKQQQLE----QEQFHAFEEMIRNQE-LEKER 178 EE R M Q+E E+EK R +++Q+Q E +E+ H EE+ R +E + ++ Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQE 502 Query: 179 LKIVQEFGKV 188 KI ++ KV Sbjct: 503 EKIRKQEEKV 512 Score = 35.4 bits (80), Expect = 0.099 Identities = 42/158 (26%), Positives = 69/158 (43%), Gaps = 19/158 (12%) Query: 43 IIRMASIYSEEGNIEHAF---ILYNKYITLFIEKLPKHRDYKSAVIPEKKDTVKKLKEIA 99 I R+ + G +E A K +IE+L K RD S + T ++LKE Sbjct: 164 ISRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEKN 223 Query: 100 FPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELE-------KEKQRVAQQ 152 E+L+ L K + N ++ K E A+ + QQ+L+ KE Q V+ + Sbjct: 224 AKLQEKLQ---LVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAK 280 Query: 153 KQQQLEQEQF------HAFEEMIRNQELEKERLKIVQE 184 Q Q+E+ + E+M R +E +E + +QE Sbjct: 281 LQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQE 318 Score = 33.5 bits (75), Expect = 0.38 Identities = 20/101 (19%), Positives = 56/101 (55%), Gaps = 2/101 (1%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQ 147 +++ + + +EI K + + E R +E EEK +E EE R ++++ ++++ Sbjct: 481 QEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ--EEKMWRQEE 538 Query: 148 RVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188 ++ +Q++ E+E+ H E++ ++ +++ K+ ++ K+ Sbjct: 539 KIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579 Score = 33.5 bits (75), Expect = 0.38 Identities = 25/89 (28%), Positives = 47/89 (52%), Gaps = 3/89 (3%) Query: 102 KAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQ 161 + EE E K + +E + E+K EE R + ++EK R ++K+Q+ E++ Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607 Query: 162 FHAFEEMIRNQE--LEKERLKIVQEFGKV 188 + EE IR QE ++++ KI ++ K+ Sbjct: 608 WKQ-EEKIREQEEKIQEQEEKIREQEEKI 635 Score = 33.5 bits (75), Expect = 0.38 Identities = 23/101 (22%), Positives = 59/101 (58%), Gaps = 8/101 (7%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQELE 143 I E+++ ++ +E + + E+++ + K + +E EEK +E EE+ + ++++ Sbjct: 593 IREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ--EEKMG 650 Query: 144 KEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQE 184 ++++++ +Q+++ EQE E M R +E +E+ K ++E Sbjct: 651 EQEEKMCEQEEKMQEQE-----ETMWRQEEKIREQEKKIRE 686 Score = 32.0 bits (71), Expect = 1.1 Identities = 28/111 (25%), Positives = 56/111 (50%), Gaps = 7/111 (6%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEEL----ARNMAIQ 139 I E ++ +++ +E + E+++ + K R +E EEK + EE+ M Q Sbjct: 309 IQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ 368 Query: 140 QEL--EKEKQRVAQQKQQQLEQEQFHAFEEMIRNQELEKERLKIVQEFGKV 188 +E+ EKE++ Q++ ++E+ EE + QE +E+ + QE K+ Sbjct: 369 EEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKI 419 Score = 31.6 bits (70), Expect = 1.4 Identities = 22/90 (24%), Positives = 50/90 (55%), Gaps = 6/90 (6%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLK-RYTKEYTEYNEEKKKEAEELARNMAIQQELEKE 145 ++++ +++ +E + E+++ + K R +E T+ EEK E EE M Q+E +E Sbjct: 609 KQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEE---KMCEQEEKMQE 665 Query: 146 KQRVAQQKQQQLEQEQ--FHAFEEMIRNQE 173 ++ ++++++ +++ EE IR QE Sbjct: 666 QEETMWRQEEKIREQEKKIREQEEKIREQE 695 Score = 30.4 bits (67), Expect = 3.2 Identities = 22/87 (25%), Positives = 45/87 (51%), Gaps = 6/87 (6%) Query: 104 EELKAELLKRYTKEYTEYNEEKKKEAEELARNM-----AIQQELEKEKQRVAQQKQQQLE 158 EE+ + K + +E +EK E EE R ++++ ++++++ +Q+++ Sbjct: 476 EEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR 535 Query: 159 QEQ-FHAFEEMIRNQELEKERLKIVQE 184 QE+ EEM R +E E+ KI +E Sbjct: 536 QEEKIREQEEMWREEEKMHEQEKIWEE 562 Score = 30.4 bits (67), Expect = 3.2 Identities = 18/62 (29%), Positives = 37/62 (59%), Gaps = 3/62 (4%) Query: 113 RYTKEYTEYNEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQ-QLEQEQFHAFEEMIRN 171 R +E EEK +E EE + ++++ K+++++ +Q+++ Q ++E+ EE IR Sbjct: 580 REQEEKVWRQEEKIREQEE--KRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637 Query: 172 QE 173 QE Sbjct: 638 QE 639 Score = 30.0 bits (66), Expect = 4.1 Identities = 22/98 (22%), Positives = 53/98 (54%), Gaps = 11/98 (11%) Query: 85 IPEKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK--------KEAEELARNM 136 I E+++ ++ +E + E++ + K +E T + +E+K +E EE R Sbjct: 635 IREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIREQ 694 Query: 137 AIQQELEKEKQRVAQQKQQQLEQEQ-FHAFEEMIRNQE 173 ++ ++++++++ +Q+++ EQE+ EE +R QE Sbjct: 695 --EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQE 730 Score = 29.6 bits (65), Expect = 5.4 Identities = 31/130 (23%), Positives = 64/130 (49%), Gaps = 12/130 (9%) Query: 67 ITLFIEKLPKHRDYKSAVIPEKKDTV------KKLKEIAFP-KAEELKAELLKRYTKEYT 119 I L +++L + + ++P+++ K+L+ ++ +A+ + EL R ++ Sbjct: 240 IQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQE 299 Query: 120 EY---NEEKKKEAEELARNMAIQQELEKEKQRVAQQKQQQLEQEQFHAFEEMIRNQEL-- 174 E EEK +E EE + + ++EK R ++K ++ E+ + E+M R +E+ Sbjct: 300 EKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 359 Query: 175 EKERLKIVQE 184 EKE QE Sbjct: 360 EKEEKMRRQE 369 Score = 29.6 bits (65), Expect = 5.4 Identities = 17/88 (19%), Positives = 53/88 (60%), Gaps = 4/88 (4%) Query: 88 KKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKK-KEAEELARNMAIQQELEKEK 146 +++ +++ +E + + E+++ + KR +E + +E+K +E EE + ++++ +++ Sbjct: 575 QEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQ--EEKIREQE 632 Query: 147 QRVAQQKQQ-QLEQEQFHAFEEMIRNQE 173 +++ +Q++ Q ++E+ EE + QE Sbjct: 633 EKIREQEEMTQEQEEKMGEQEEKMCEQE 660 Score = 29.3 bits (64), Expect = 7.1 Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 6/83 (7%) Query: 112 KRYTKEYTEYNEEKKKEAEELARNMAIQQELE----KEKQRVAQQKQQQLEQEQF--HAF 165 KR +E EEK E EE+ R E E K++++V +Q+++ EQE+ Sbjct: 471 KRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQE 530 Query: 166 EEMIRNQELEKERLKIVQEFGKV 188 E+M R +E +E+ ++ +E K+ Sbjct: 531 EKMWRQEEKIREQEEMWREEEKM 553 Score = 29.3 bits (64), Expect = 7.1 Identities = 19/88 (21%), Positives = 48/88 (54%), Gaps = 7/88 (7%) Query: 87 EKKDTVKKLKEIAFPKAEELKAELLKRYTKEYTEYNEEKKKEAEELARNMAIQQELEKEK 146 E+++ +++ +E + + E+++ + K EEK +E EE+ + ++ E+E+ Sbjct: 658 EQEEKMQEQEETMWRQEEKIREQEKK------IREQEEKIREQEEMMQEQE-EKMWEQEE 710 Query: 147 QRVAQQKQQQLEQEQFHAFEEMIRNQEL 174 + Q+++ Q ++E+ EE + QE+ Sbjct: 711 KMCEQEEKMQEQEEKMRRQEEKMWEQEV 738 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,250,894 Number of Sequences: 37866 Number of extensions: 828468 Number of successful extensions: 12826 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 277 Number of HSP's successfully gapped in prelim test: 610 Number of HSP's that attempted gapping in prelim test: 6238 Number of HSP's gapped (non-prelim): 4354 length of query: 424 length of database: 18,247,518 effective HSP length: 105 effective length of query: 319 effective length of database: 14,271,588 effective search space: 4552636572 effective search space used: 4552636572 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.