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Search of human proteins with 54112397
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
subunit [Homo sapiens]
(1091 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3 ... 2199 0.0
gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subun... 1354 0.0
gi|54112394 calcium channel, voltage-dependent, alpha 2/delta su... 431 e-120
gi|54112392 calcium channel, voltage-dependent, alpha 2/delta su... 426 e-119
gi|54112390 calcium channel, voltage-dependent, alpha 2/delta su... 401 e-111
gi|110578649 cache domain containing 1 [Homo sapiens] 91 5e-18
gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo ... 59 3e-08
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] 54 6e-07
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens] 52 4e-06
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 48 4e-05
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ... 47 8e-05
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor... 47 8e-05
gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor... 47 8e-05
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens] 44 8e-04
gi|71061468 centromere protein E [Homo sapiens] 35 0.39
gi|4557353 branched chain keto acid dehydrogenase E1 beta precur... 34 0.86
gi|34101272 branched chain keto acid dehydrogenase E1 beta precu... 34 0.86
gi|11321565 matrilin 3 precursor [Homo sapiens] 32 2.5
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ... 32 2.5
gi|194306644 BCSC-1 isoform 1 [Homo sapiens] 32 3.3
gi|38195080 BCSC-1 isoform 1 [Homo sapiens] 32 3.3
gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo... 32 4.3
gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo... 31 5.6
gi|40548332 coiled-coil domain containing 137 [Homo sapiens] 31 5.6
gi|56711320 hypothetical protein LOC145407 [Homo sapiens] 31 5.6
gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens] 31 7.3
gi|13375985 zinc finger, AN1-type domain 1 [Homo sapiens] 31 7.3
gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 30 9.5
gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 30 9.5
gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens] 30 9.5
>gi|54112397 calcium channel, voltage-dependent, alpha 2/delta 3
subunit [Homo sapiens]
Length = 1091
Score = 2199 bits (5697), Expect = 0.0
Identities = 1091/1091 (100%), Positives = 1091/1091 (100%)
Query: 1 MAGPGSPRRASRGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKY 60
MAGPGSPRRASRGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKY
Sbjct: 1 MAGPGSPRRASRGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKY 60
Query: 61 SGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKH 120
SGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKH
Sbjct: 61 SGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKH 120
Query: 121 EFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYN 180
EFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYN
Sbjct: 121 EFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYN 180
Query: 181 KDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFD 240
KDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFD
Sbjct: 181 KDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFD 240
Query: 241 CRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEE 300
CRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEE
Sbjct: 241 CRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEE 300
Query: 301 LHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSI 360
LHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSI
Sbjct: 301 LHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSI 360
Query: 361 CSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQ 420
CSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQ
Sbjct: 361 CSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQ 420
Query: 421 ISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVA 480
ISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVA
Sbjct: 421 ISTLADVQENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVA 480
Query: 481 MPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELR 540
MPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELR
Sbjct: 481 MPVFSKQNETRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELR 540
Query: 541 LLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVM 600
LLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVM
Sbjct: 541 LLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVM 600
Query: 601 TNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDL 660
TNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDL
Sbjct: 601 TNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDL 660
Query: 661 HPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSD 720
HPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSD
Sbjct: 661 HPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSD 720
Query: 721 KGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGS 780
KGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGS
Sbjct: 721 KGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGS 780
Query: 781 FVYSIPFSTGPVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCAS 840
FVYSIPFSTGPVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCAS
Sbjct: 781 FVYSIPFSTGPVNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCAS 840
Query: 841 LDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITL 900
LDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITL
Sbjct: 841 LDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITL 900
Query: 901 YDYQAMCRANKESSDGAHGLLDPYNAFLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQ 960
YDYQAMCRANKESSDGAHGLLDPYNAFLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQ
Sbjct: 901 YDYQAMCRANKESSDGAHGLLDPYNAFLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQ 960
Query: 961 KLKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCE 1020
KLKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCE
Sbjct: 961 KLKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCE 1020
Query: 1021 SVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSLQAQTVLL 1080
SVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSLQAQTVLL
Sbjct: 1021 SVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSLQAQTVLL 1080
Query: 1081 LLPLLLMLFSR 1091
LLPLLLMLFSR
Sbjct: 1081 LLPLLLMLFSR 1091
>gi|132566536 voltage-gated calcium channel alpha(2)delta-4 subunit
[Homo sapiens]
Length = 1137
Score = 1354 bits (3505), Expect = 0.0
Identities = 648/1083 (59%), Positives = 842/1083 (77%), Gaps = 20/1083 (1%)
Query: 15 SALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAKYSGSQLLQKKYKEYE 74
SALL LL +L + +IPL VKLWA FGG++ + KYSGS LLQKKYK+ E
Sbjct: 51 SALLWLLLLGTSLSPAW-GQAKIPLETVKLWADTFGGDLYNTVTKYSGSLLLQKKYKDVE 109
Query: 75 KDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADLQYEYFNAV 134
+ IEE+DGL+LV+K +++ME M +K EAV+ LVEAAEEA L HEF+ L ++Y+N+V
Sbjct: 110 SSLKIEEVDGLELVRKFSEDMENMLRRKVEAVQNLVEAAEEADLNHEFNESLVFDYYNSV 169
Query: 135 LINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSDVQVPTNMYNKDPAIVNGVYWSES 194
LINERD+ GNF+ELG EF+L N HF+NLPVN S+S VQ+PTN+YNKDP I+NGVY SE+
Sbjct: 170 LINERDEKGNFVELGAEFLLESNAHFSNLPVNTSISSVQLPTNVYNKDPDILNGVYMSEA 229
Query: 195 LNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSP 254
LN VFV+NF RDP+L WQYFGSA GFFR YPGIKW PDENGVI FDCRNR WYIQAATSP
Sbjct: 230 LNAVFVENFQRDPTLTWQYFGSATGFFRIYPGIKWTPDENGVITFDCRNRGWYIQAATSP 289
Query: 255 KDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQ 314
KD+VILVDVSGSMKGLR+TIAK T+++ILDTLG++DF NIIAYN+ +HY+EPC G LVQ
Sbjct: 290 KDIVILVDVSGSMKGLRMTIAKHTITTILDTLGENDFINIIAYNDYVHYIEPCFKGILVQ 349
Query: 315 ADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQAIMLITDGAVD 374
ADR N+EHF+ +++L KG+G++D AL EAF IL F QGS+C+QAIMLI+DGAV+
Sbjct: 350 ADRDNREHFKLLVEELMVKGVGVVDQALREAFQILKQFQEAKQGSLCNQAIMLISDGAVE 409
Query: 375 TYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADVQENVMEY 434
Y+ +F KYNWPD KVR+FTYLIGRE +FAD +KW+AC NKG++TQISTLAD QENVMEY
Sbjct: 410 DYEPVFEKYNWPDCKVRVFTYLIGREVSFADRMKWIACNNKGYYTQISTLADTQENVMEY 469
Query: 435 LHVLSRPKVIDQEHDVVWTEAYIDSTL--PQAQKLTDDQGPVLMTTVAMPVFSKQNETRS 492
LHVLSRP VI+ +HD++WTEAY+DS L QAQ LT L+TTVAMPVFSK+NETRS
Sbjct: 470 LHVLSRPMVINHDHDIIWTEAYMDSKLLSSQAQSLT------LLTTVAMPVFSKKNETRS 523
Query: 493 KGILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLYEEGKK-RRK 551
GILLGVVG+DV ++EL+K P+YKLG+HGYAF TNNGYIL+HP+LR LY EGKK + K
Sbjct: 524 HGILLGVVGSDVALRELMKLAPRYKLGVHGYAFLNTNNGYILSHPDLRPLYREGKKLKPK 583
Query: 552 PNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKG 611
PNY+SVDLSEVEWED+ + LR AM+NR+TG SM+VK +DKGKRVL +TNDY++TDI
Sbjct: 584 PNYNSVDLSEVEWEDQAESLRTAMINRETGTLSMDVKVPMDKGKRVLFLTNDYFFTDISD 643
Query: 612 TPFSLGVALSRGHGKYFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLE 671
TPFSLGV LSRGHG+Y GN ++EEGLHDL HPD++LA +W YC TD+ P+HR LSQLE
Sbjct: 644 TPFSLGVVLSRGHGEYILLGNTSVEEGLHDLLHPDLALAGDWIYCITDIDPDHRKLSQLE 703
Query: 672 AIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTR 731
A+ +L K+P L+CD+EL++EVLFDAVV+AP+EAYWT+LALN SE S+ V++AFLGTR
Sbjct: 704 AMIRFLTRKDPDLECDEELVREVLFDAVVTAPMEAYWTALALNMSEESEHVVDMAFLGTR 763
Query: 732 TGLSRINLFVGAEQLTNQDFLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGP 791
GL R +LFVG+E+++++ FL D+ ++F D FPLWYR+A+E GSFV+++ ++ GP
Sbjct: 764 AGLLRSSLFVGSEKVSDRKFLTPEDEASVFTLDRFPLWYRQASEHPAGSFVFNLRWAEGP 823
Query: 792 --VNKSNVVTASTSIQLLDERKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISC 849
+ VVTAST++ + ++++ + AA G+QMKLEF QRKFW A+RQC+++DG C+ SC
Sbjct: 824 ESAGEPMVVTASTAVAVTVDKRTAIAAAAGVQMKLEFLQRKFWAATRQCSTVDGPCTQSC 883
Query: 850 DDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRA 909
+D ++C++IDNNGFIL+S+ +TG F GE++GAV+ +LL+MG F ++T+YDYQAMC+
Sbjct: 884 EDSDLDCFVIDNNGFILISKRSRETGRFLGEVDGAVLTQLLSMGVFSQVTMYDYQAMCKP 943
Query: 910 NKESSDGAHGLLDPYNAFLSAVKWIMTELVLFLVEFNLC-SWWHSDMTAKA-------QK 961
+ A L+ P +AFL+A +W++ ELVLFL+E+++ SW+ AK+ K
Sbjct: 944 SSHHHSAAQPLVSPISAFLTATRWLLQELVLFLLEWSVWGSWYDRGAEAKSVFHHSHKHK 1003
Query: 962 LKQTLEPCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCES 1021
+ L+PCDTEYP FV + I+E G + C C K FV+QQIP+SNL ++V D +C C
Sbjct: 1004 KQDPLQPCDTEYPVFVYQPAIREANGIVECGPCQKVFVVQQIPNSNLLLLVTDPTCDCSI 1063
Query: 1022 VAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSLQAQTVLLL 1081
P+ E++YN S+KC+R+++QK+RRRP+SCH FHPEENA++CGGA A LLL
Sbjct: 1064 FPPVLQEATEVKYNASVKCDRMRSQKLRRRPDSCHAFHPEENAQDCGGASDTSASPPLLL 1123
Query: 1082 LPL 1084
LP+
Sbjct: 1124 LPV 1126
>gi|54112394 calcium channel, voltage-dependent, alpha 2/delta subunit
2 isoform b [Homo sapiens]
Length = 1143
Score = 431 bits (1108), Expect = e-120
Identities = 339/1148 (29%), Positives = 560/1148 (48%), Gaps = 114/1148 (9%)
Query: 3 GPGSPRRAS---RGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAK 59
GPG+ R S R LL L AA G S Q ++ WA E+ +
Sbjct: 30 GPGTRRPTSGPPRPLWLLLPLLPLLAAPGASAYSFPQ--QHTMQHWARRLEQEVDGVMRI 87
Query: 60 YSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLK 119
+ G Q L++ YK+ ++E + +LV+K+A ++E + +K +A++RL +AAE
Sbjct: 88 FGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKA 147
Query: 120 HEFDADLQYE---YFNAVLINERDK-DGNFLELGK-------EFILAPNDHFNNLPVNIS 168
H + +++ E Y++A E D + +E G +FI PN F N VN S
Sbjct: 148 HRWQDNIKEEDIVYYDAKADAELDDPESEDVERGSKASTLRLDFIEDPN--FKN-KVNYS 204
Query: 169 LSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIK 228
+ VQ+PT++Y I+N + W+E+L VF++N +DP+L+WQ FGSA G R YP
Sbjct: 205 YAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGSATGVTRYYPATP 264
Query: 229 WEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGD 288
W + + +D R R WYIQ A+SPKD+VI+VDVSGS+ GL L + K +V +LDTL D
Sbjct: 265 WRAPKK-IDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSD 323
Query: 289 DDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNI 348
DD+ N+ ++NE+ V C LVQA+ NK+ F+E + + AKG AF+
Sbjct: 324 DDYVNVASFNEKAQPVS-CFTH-LVQANVRNKKVFKEAVQGMVAKGTTGYKAGFEYAFDQ 381
Query: 349 LSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLK 408
L + N T C++ IM+ TDG D +F KYNWP+R VR+FT+ +G+ L+
Sbjct: 382 LQNSNITRAN--CNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQ 439
Query: 409 WMACANKGFFTQISTLADVQENVMEYLHVLSRPKVI--DQEHDVVWTEAYIDSTLPQAQK 466
WMACANKG++ +I ++ ++ N EYL VL RP V+ + V WT Y D+
Sbjct: 440 WMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDAL------ 493
Query: 467 LTDDQGPVLMTTVAMPVFSKQNE---TRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGY 523
G L+ T +PVF+ + + ++LGV+G DV + ++ + P Y LG +GY
Sbjct: 494 -----GLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGY 548
Query: 524 AFAITNNGYILTHPELRLLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKF 583
FAI NGY+L HP L+ + R+P +E+E E+++++ R+ + K K
Sbjct: 549 VFAIDLNGYVLLHPNLK---PQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKGHKQ 605
Query: 584 SMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLE 643
+ K++D+ + + +T +Y + I+ T +SLG+ L + ++ + N + + + ++
Sbjct: 606 IRTLVKSLDE-RYIDEVTRNYTWVPIRSTNYSLGLVLP-PYSTFYLQAN--LSDQILQVK 661
Query: 644 HPDVSLADEW-----------SYCNTDLHPEHRHLSQLE-AIKLYLKGKEPLLQCDKELI 691
+ + L + YC DL+ + L+ I+L K QC+ L+
Sbjct: 662 YFEFLLPSSFESEGHVFIAPREYCK-DLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLL 720
Query: 692 QEVLFD-AVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQD 750
++ D + +E W LN + F T G++R+ AE T
Sbjct: 721 HNLILDTGITQQLVERVWRDQDLN-----TYSLLAVFAATDGGITRVFPNKAAEDWT--- 772
Query: 751 FLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGPV------NKSNVVTASTSI 804
+ FNA +YRR+ + +V+ P + N + + ST++
Sbjct: 773 -----ENPEPFNAS----FYRRSLDN--HGYVFKPPHQDALLRPLELENDTVGILVSTAV 821
Query: 805 QLLDERKSPVVAAVGIQMKLEFFQRKFWTASR--------QCASLDGKCSISCD--DETV 854
+L R++ A VG+++ LE + KF + Q + C + C+ +E +
Sbjct: 822 ELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPNSHCEMDCEVNNEDL 881
Query: 855 NCYLIDNNGFILVS---EDYTQTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRANK 911
C LID+ GF+++S + Q G FF E++ +M L + R YDYQA C
Sbjct: 882 LCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQP 941
Query: 912 ESSDGA--HGLLDPYNA-------FLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQKL 962
+ GA G+ P A + SA W + + +L+ + ++ SW+ +D A+A+
Sbjct: 942 PGNLGAAPRGVFVPTVADFLNLAWWTSAAAWSLFQQLLYGLIYH--SWFQAD-PAEAEGS 998
Query: 963 KQTLE-PCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSSCLCES 1021
+T E C + + I C +CS+ F Q++ ++NL VV + LC
Sbjct: 999 PETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKP-LCSQ 1057
Query: 1022 VAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECG-GAPSLQAQTVLL 1080
+ E + +CE ++ + RR P C ++ E+ +CG GA + VL+
Sbjct: 1058 CEAGRLLQKETHSDGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVLV 1117
Query: 1081 LLPLLLML 1088
L LLL+L
Sbjct: 1118 SLQLLLLL 1125
>gi|54112392 calcium channel, voltage-dependent, alpha 2/delta subunit
2 isoform a [Homo sapiens]
Length = 1145
Score = 426 bits (1095), Expect = e-119
Identities = 337/1149 (29%), Positives = 558/1149 (48%), Gaps = 114/1149 (9%)
Query: 3 GPGSPRRAS---RGASALLAAALLYAALGDVVRSEQQIPLSVVKLWASAFGGEIKSIAAK 59
GPG+ R S R LL L AA G S Q ++ WA E+ +
Sbjct: 30 GPGTRRPTSGPPRPLWLLLPLLPLLAAPGASAYSFPQ--QHTMQHWARRLEQEVDGVMRI 87
Query: 60 YSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLK 119
+ G Q L++ YK+ ++E + +LV+K+A ++E + +K +A++RL +AAE
Sbjct: 88 FGGVQQLREIYKDNRNLFEVQENEPQKLVEKVAGDIESLLDRKVQALKRLADAAENFQKA 147
Query: 120 HEFDADLQYE---YFNAVLINERDK-DGNFLELGK-------EFILAPNDHFNNLPVNIS 168
H + +++ E Y++A E D + +E G +FI PN F N VN S
Sbjct: 148 HRWQDNIKEEDIVYYDAKADAELDDPESEDVERGSKASTLRLDFIEDPN--FKN-KVNYS 204
Query: 169 LSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIK 228
+ VQ+PT++Y I+N + W+E+L VF++N +DP+L+WQ FGSA G R YP
Sbjct: 205 YAAVQIPTDIYKGSTVILNELNWTEALENVFMENRRQDPTLLWQVFGSATGVTRYYPATP 264
Query: 229 WEPDENGVIAFDCRNRKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGD 288
W + + +D R R WYIQ A+SPKD+VI+VDVSGS+ GL L + K +V +LDTL D
Sbjct: 265 WRAPKK-IDLYDVRRRPWYIQGASSPKDMVIIVDVSGSVSGLTLKLMKTSVCEMLDTLSD 323
Query: 289 DDFFNIIAYNEELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNI 348
DD+ N+ ++NE+ V C LVQA+ NK+ F+E + + AKG AF+
Sbjct: 324 DDYVNVASFNEKAQPVS-CFTH-LVQANVRNKKVFKEAVQGMVAKGTTGYKAGFEYAFDQ 381
Query: 349 LSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLK 408
L + N T C++ IM+ TDG D +F KYNWP+R VR+FT+ +G+ L+
Sbjct: 382 LQNSNITRAN--CNKMIMMFTDGGEDRVQDVFEKYNWPNRTVRVFTFSVGQHNYDVTPLQ 439
Query: 409 WMACANKGFFTQISTLADVQENVMEYLHVLSRPKVI--DQEHDVVWTEAYIDSTLPQAQK 466
WMACANKG++ +I ++ ++ N EYL VL RP V+ + V WT Y D+
Sbjct: 440 WMACANKGYYFEIPSIGAIRINTQEYLDVLGRPMVLAGKEAKQVQWTNVYEDAL------ 493
Query: 467 LTDDQGPVLMTTVAMPVFSKQNE---TRSKGILLGVVGTDVPVKELLKTIPKYKLGIHGY 523
G L+ T +PVF+ + + ++LGV+G DV + ++ + P Y LG +GY
Sbjct: 494 -----GLGLVVTGTLPVFNLTQDGPGEKKNQLILGVMGIDVALNDIKRLTPNYTLGANGY 548
Query: 524 AFAITNNGYILTHPELRLLYEEGKKRRKPNYSSVDLSEVEWEDRDDVLRNAMVNRKTGKF 583
FAI NGY+L HP L+ + R+P +E+E E+++++ R+ + K K
Sbjct: 549 VFAIDLNGYVLLHPNLK---PQTTNFREPVTLDFLDAELEDENKEEIRRSMIDGNKGHKQ 605
Query: 584 SMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFFRGNVTIEEGLHDLE 643
+ K++D+ + + +T +Y + I+ T +SLG+ L + ++ + N + + + ++
Sbjct: 606 IRTLVKSLDE-RYIDEVTRNYTWVPIRSTNYSLGLVLP-PYSTFYLQAN--LSDQILQVK 661
Query: 644 HPDVSLADEW-----------SYCNTDLHPEHRHLSQLE-AIKLYLKGKEPLLQCDKELI 691
+ + L + YC DL+ + L+ I+L K QC+ L+
Sbjct: 662 YFEFLLPSSFESEGHVFIAPREYCK-DLNASDNNTEFLKNFIELMEKVTPDSKQCNNFLL 720
Query: 692 QEVLFD-AVVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQD 750
++ D + +E W LN + F T G++R+ AE T
Sbjct: 721 HNLILDTGITQQLVERVWRDQDLN-----TYSLLAVFAATDGGITRVFPNKAAEDWT--- 772
Query: 751 FLKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPFSTGPV------NKSNVVTASTSI 804
+ FNA +YRR+ + +V+ P + N + + ST++
Sbjct: 773 -----ENPEPFNAS----FYRRSLDN--HGYVFKPPHQDALLRPLELENDTVGILVSTAV 821
Query: 805 QLLDERKSPVVAAVGIQMKLEFFQRKFWTASR--------QCASLDGKCSISCD--DETV 854
+L R++ A VG+++ LE + KF + Q + C + C+ +E +
Sbjct: 822 ELSLGRRTLRPAVVGVKLDLEAWAEKFKVLASNRTHQDQPQKCGPNSHCEMDCEVNNEDL 881
Query: 855 NCYLIDNNGFILVS---EDYTQTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRANK 911
C LID+ GF+++S + Q G FF E++ +M L + R YDYQA C
Sbjct: 882 LCVLIDDGGFLVLSNQNHQWDQVGRFFSEVDANLMLALYNNSFYTRKESYDYQAACAPQP 941
Query: 912 ESSDGA--HGLLDPYNA-------FLSAVKWIMTELVLFLVEFNLCSWWHSDMTAKAQKL 962
+ GA G+ P A + SA W + + +L+ + ++ SW+ +D A+A+
Sbjct: 942 PGNLGAAPRGVFVPTVADFLNLAWWTSAAAWSLFQQLLYGLIYH--SWFQAD-PAEAEGS 998
Query: 963 KQTLE-PCDTEYPAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDSS-CLCE 1020
+T E C + + I C +CS+ F Q++ ++NL VV + C
Sbjct: 999 PETRESSCVMKQTQYYFGSVNASYNAIIDCGNCSRLFHAQRLTNTNLLFVVAEKPLCSQC 1058
Query: 1021 SVAPITMAPIEIRYNESLKCERLKAQKIRRRPESCHGFHPEENARECG-GAPSLQAQTVL 1079
+ + +CE ++ + RR P C ++ E+ +CG GA + VL
Sbjct: 1059 EAGRLLQKETHCPADGPEQCELVQRPRYRRGPHICFDYNATEDTSDCGRGASFPPSLGVL 1118
Query: 1080 LLLPLLLML 1088
+ L LLL+L
Sbjct: 1119 VSLQLLLLL 1127
>gi|54112390 calcium channel, voltage-dependent, alpha 2/delta subunit
1 [Homo sapiens]
Length = 1091
Score = 401 bits (1030), Expect = e-111
Identities = 319/1122 (28%), Positives = 546/1122 (48%), Gaps = 121/1122 (10%)
Query: 14 ASALLAAAL-LYAALGDVVRSEQQIPLSV-VKLWASAFGGEIKSIAAKYSGSQLLQKKYK 71
A LLA L L+ +L SE+ P +V +K W ++ ++A SG L Y+
Sbjct: 3 AGCLLALTLTLFQSLLIGPSSEEPFPSAVTIKSWVDKMQEDLVTLAKTASGVNQLVDIYE 62
Query: 72 EYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAVRRLVEAAEEAHLKHEFDADL---QY 128
+Y+ +E + QLV+ A+++E++ +S+A+ RL AE+ H++ D +
Sbjct: 63 KYQDLYTVEPNNARQLVEIAARDIEKLLSNRSKALVRLALEAEKVQAAHQWREDFASNEV 122
Query: 129 EYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNISLSD--VQVPTNMYNKDPAIV 186
Y+NA ++ D + N E G + I N IS V +PT++Y ++
Sbjct: 123 VYYNAK--DDLDPEKNDSEPGSQRIKPVFIEDANFGRQISYQHAAVHIPTDIYEGSTIVL 180
Query: 187 NGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIKWEPDE---NGVIAFDCRN 243
N + W+ +L++VF N + DPSL+WQ FGSA G R YP W + N + +D R
Sbjct: 181 NELNWTSALDEVFKKNREEDPSLLWQVFGSATGLARYYPASPWVDNSRTPNKIDLYDVRR 240
Query: 244 RKWYIQAATSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHY 303
R WYIQ A SPKD++ILVDVSGS+ GL L + + +VS +L+TL DDDF N+ ++N
Sbjct: 241 RPWYIQGAASPKDMLILVDVSGSVSGLTLKLIRTSVSEMLETLSDDDFVNVASFNSNAQD 300
Query: 304 VEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICSQ 363
V C LVQA+ NK+ ++ ++ + AKGI + AF L ++N + C++
Sbjct: 301 VS-CFQ-HLVQANVRNKKVLKDAVNNITAKGITDYKKGFSFAFEQLLNYNVSRAN--CNK 356
Query: 364 AIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQIST 423
IML TDG + IF KYN D+KVR+FT+ +G+ ++WMAC NKG++ +I +
Sbjct: 357 IIMLFTDGGEERAQEIFNKYN-KDKKVRVFTFSVGQHNYDRGPIQWMACENKGYYYEIPS 415
Query: 424 LADVQENVMEYLHVLSRPKVI--DQEHDVVWTEAYIDSTLPQAQKLTDDQGPVLMTTVAM 481
+ ++ N EYL VL RP V+ D+ V WT Y+D+ + G L+ T +
Sbjct: 416 IGAIRINTQEYLDVLGRPMVLAGDKAKQVQWTNVYLDAL---------ELG--LVITGTL 464
Query: 482 PVFS----KQNETRSKG-ILLGVVGTDVPVKELLKTIPKYKLGIHGYAFAITNNGYILTH 536
PVF+ +N+T K ++LGV+G DV ++++ + P++ L +GY FAI NGY+L H
Sbjct: 465 PVFNITGQFENKTNLKNQLILGVMGVDVSLEDIKRLTPRFTLCPNGYYFAIDPNGYVLLH 524
Query: 537 PELRLLYEEGKKRRKPNYSSVDLSEVEWEDRDDV-LRNAMVNRKTGKFSMEV------KK 589
P L+ + K ++P ++D + E E+ V +RN M++ ++G+ + ++
Sbjct: 525 PNLQ---PKNPKSQEP--VTLDFLDAELENDIKVEIRNKMIDGESGEKTFRTLVKSQDER 579
Query: 590 TVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGKYFF--------------RGNVTI 635
+DKG R Y +T + GT +SL + L + Y+ +G +
Sbjct: 580 YIDKGNRT------YTWTPVNGTDYSLALVLPT-YSFYYIKAKLEETITQARSKKGKMKD 632
Query: 636 EEGL--HDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEP-LLQCDKELIQ 692
E L + E + YCN DL + L ++ K P C+ +LI
Sbjct: 633 SETLKPDNFEESGYTFIAPRDYCN-DLKISDNNTEFLLNFNEFIDRKTPNNPSCNADLIN 691
Query: 693 EVLFDA-VVSAPIEAYWTSLALNKSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDF 751
VL DA + ++ YW+ + + KGV+ F+ T G++R+
Sbjct: 692 RVLLDAGFTNELVQNYWS------KQKNIKGVKARFVVTDGGITRVYP------------ 733
Query: 752 LKAGDKENIFNADHFPLWYRRAAEQIPGSFVYSIPF--STGPVNKSNVVTASTSIQLLDE 809
+AG+ + +Y+R+ + ++V++ P+ +GP + + S ++++ +
Sbjct: 734 KEAGENWQENPETYEDSFYKRSLDN--DNYVFTAPYFNKSGPGAYESGIMVSKAVEIYIQ 791
Query: 810 RKSPVVAAVGIQMKLEFFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVS- 868
K A VGI++ + + F S + C + + ++C ++D+ GF+L++
Sbjct: 792 GKLLKPAVVGIKIDVNSWIENFTKTSIRDPCAGPVCDCKRNSDVMDCVILDDGGFLLMAN 851
Query: 869 -EDYT-QTGDFFGEIEGAVMNKLLTMGSFKRITLYDYQAMCRANKESSDGA--HGLLDPY 924
+DYT Q G FFGEI+ ++M L+ + + YDYQ++C GA P
Sbjct: 852 HDDYTNQIGRFFGEIDPSLMRHLVNISVYAFNKSYDYQSVCEPGAAPKQGAGHRSAYVPS 911
Query: 925 NAFLSAVKWIMTELVLFLVEFNLCS-----------WWHSDMTAKAQKLKQTLEPCDTEY 973
A + + W T +++ L S D TA K + C TE
Sbjct: 912 VADILQIGWWATAAAWSILQQFLLSLTFPRLLEAVEMEDDDFTASLSK-----QSCITEQ 966
Query: 974 PAFVSERTIKETTGNIACEDCSKSFVIQQIPSSNLFMVVVDS--SCLCESVAPITMAPIE 1031
+ + K +G + C +CS+ F +++ ++NL ++V+S +C C++ I
Sbjct: 967 TQYFFDNDSKSFSGVLDCGNCSRIFHGEKLMNTNLIFIMVESKGTCPCDTRLLIQAEQTS 1026
Query: 1032 IRYNESLKCERLKAQKIRRRPESCHGFHPEENARECGGAPSL 1073
N C+ +K + R+ P+ C + E+ +CGG L
Sbjct: 1027 DGPN---PCDMVKQPRYRKGPDVCFDNNVLEDYTDCGGVSGL 1065
>gi|110578649 cache domain containing 1 [Homo sapiens]
Length = 1223
Score = 91.3 bits (225), Expect = 5e-18
Identities = 113/521 (21%), Positives = 209/521 (40%), Gaps = 76/521 (14%)
Query: 53 IKSIAAKYSGSQLLQKKYKEYEKDVAIEEI-DGLQLVKKLAKNMEEMFHKKSEAVRR--- 108
++ +AA+ G +Q+ + + V E+I +G V++LAK + E F++ + V R
Sbjct: 1 MRRLAAEELGVVTMQRIFNSF---VYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQ 57
Query: 109 LVEAAEEAHLKHEFDADLQYEYFNAVLINERDKDGNFLELGKEFILAPNDHFNNLPVNIS 168
+VEA+ AHL A + + + + DGNF N+ IS
Sbjct: 58 VVEASYTAHLTSPLTA---IQDCCTIPPSMMEFDGNFN--------------TNVSRTIS 100
Query: 169 LSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYPGIK 228
+ N +P LN V DN +P + WQYF S +G F +P K
Sbjct: 101 CDRLSTTVNSRAFNPG--------RDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHK 152
Query: 229 WEPDENGVIAFDCRNRKWYIQAAT-SPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLG 287
+ + ++ R+R Y+ K +V+++D S+ +L IAK IL +
Sbjct: 153 FRCKGS----YEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAID 208
Query: 288 DDDFFNIIAYNEELHY--VEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLD-IALNE 344
+ D +++ + + ++ C L A K + + + + +
Sbjct: 209 EHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQK 268
Query: 345 AFNILSDFNHTGQGSICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFA 404
AF ++ N+ + + +++ + + D+ + D+K + +I E +F
Sbjct: 269 AFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDS-----SEEDKKATL--QVINEENSFL 321
Query: 405 DN---LKWMACANKGF--FTQISTLADVQENVMEYLHVLSRPK---------VIDQEHDV 450
+N + A N G +++ L D+ E V R V++Q ++
Sbjct: 322 NNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNL 381
Query: 451 VWTEAYIDSTLPQAQ--------KLTDDQGPVLMTTVAMPVFSKQNETRSKGILLGVVGT 502
T + LP +D+ G L+ TV+ P + +LLG+VG
Sbjct: 382 ETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGN-------LLLGIVGV 434
Query: 503 DVPVKELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLY 543
DV + +L+ + Y+ + Y F I + GY L HP L Y
Sbjct: 435 DVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPY 475
Score = 30.8 bits (68), Expect = 7.3
Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 11/76 (14%)
Query: 209 LIWQYFGSAKGFFRQYPGIKWEPDENGVIAFDCRNRKWYIQAATSPKDVVI---LVDVSG 265
++ +Y + G R YPG + AFD R+WY+ A +P + + +DV G
Sbjct: 677 IVRRYIATPNGVLRIYPGSLMDK------AFDPTRRQWYLHAVANPGLISLTGPYLDVGG 730
Query: 266 SMKGLRLTIAKQTVSS 281
+ G +TI+ SS
Sbjct: 731 A--GYVVTISHTIHSS 744
>gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
sapiens]
Length = 946
Score = 58.5 bits (140), Expect = 3e-08
Identities = 48/195 (24%), Positives = 96/195 (49%), Gaps = 13/195 (6%)
Query: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313
PK+++ ++DVSGSM G+++ + + +ILD L +D F++I +N+ + L+
Sbjct: 308 PKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLRAEDHFSVIDFNQNIR----TWRNDLI 363
Query: 314 QADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGSICS-QAIMLITDGA 372
A +T + +++K+ G ++ AL A IL++ N+ G S I+L++DG
Sbjct: 364 SATKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGD 423
Query: 373 VDTYDTIFAKY------NWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLAD 426
+ +K N D + +F+ +G + + D LK ++ N G +I D
Sbjct: 424 PTVGELKLSKIQKNVKENIQD-NISLFSLGMGFDVDY-DFLKRLSNENHGIAQRIYGNQD 481
Query: 427 VQENVMEYLHVLSRP 441
+ ++ + +S P
Sbjct: 482 TSSQLKKFYNQVSTP 496
>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
Length = 1313
Score = 54.3 bits (129), Expect = 6e-07
Identities = 52/199 (26%), Positives = 95/199 (47%), Gaps = 12/199 (6%)
Query: 255 KDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQ 314
K+VV ++DVS SM G ++ K ++ IL L +D+FNII++++ ++ + G +Q
Sbjct: 282 KNVVFVIDVSSSMFGTKMEQTKTAMNVILSDLQANDYFNIISFSDTVNVWKA---GGSIQ 338
Query: 315 ADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFN-HTGQGSICSQ--AIMLITDG 371
A N +++L + A G ++ AL A ++L+ N G+G + I+ +TDG
Sbjct: 339 ATIQNVHSAKDYLHCMEADGWTDVNSALLAAASVLNHSNQEPGRGPSVGRIPLIIFLTDG 398
Query: 372 ----AVDTYDTIFAKYNWP-DRKVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLAD 426
V T I + +V +F+ G +A F L+ ++ N+G +I D
Sbjct: 399 EPTAGVTTPSVILSNVRQALGHRVSLFSLAFGDDADFT-LLRRLSLENRGIARRIYEDTD 457
Query: 427 VQENVMEYLHVLSRPKVID 445
+ +S P + D
Sbjct: 458 AALQLKGLYEEISMPLLAD 476
>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
Length = 930
Score = 51.6 bits (122), Expect = 4e-06
Identities = 39/123 (31%), Positives = 60/123 (48%), Gaps = 9/123 (7%)
Query: 252 TSPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGT 311
T PK+VV ++D SGSM G ++ ++ + ILD L D FN+I ++ E P +
Sbjct: 270 TMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRP----S 325
Query: 312 LVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFN---HTGQGSICSQAIMLI 368
LV A N R + A G ++ A+ A +L N +GS+ I+L+
Sbjct: 326 LVPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSV--SLIILL 383
Query: 369 TDG 371
TDG
Sbjct: 384 TDG 386
>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
[Homo sapiens]
Length = 890
Score = 48.1 bits (113), Expect = 4e-05
Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 17/197 (8%)
Query: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313
PK+V ++D+SGSM G +L K+ + IL+ + ++D+ N I ++ ++ LV
Sbjct: 282 PKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDV----STWKEHLV 337
Query: 314 QADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQ-GSICSQAIMLITDGA 372
QA N + R + + KG+ ++ L ++L+ + + ++++TDG
Sbjct: 338 QATPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHRIPERSTSIVIMLTDGD 397
Query: 373 VDTYDTIFAKYNWPDRKV---RIFTYLIGREAAFADNLKW-----MACANKGFFTQISTL 424
+ ++ K R + Y +G F +NL + MA N GF +I
Sbjct: 398 ANVGESRPEKIQENVRNAIGGKFPLYNLG----FGNNLNYNFLENMALENHGFARRIYED 453
Query: 425 ADVQENVMEYLHVLSRP 441
+D + + ++ P
Sbjct: 454 SDADLQLQGFYEEVANP 470
>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 3 [Homo sapiens]
Length = 702
Score = 47.4 bits (111), Expect = 8e-05
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 17/219 (7%)
Query: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313
PK+VV ++D S SM G +L K + +IL L D F+II ++ + + L
Sbjct: 293 PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTP 352
Query: 314 QADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDF-NHTGQGSICSQAIMLITDGA 372
+ R K ++ + G ++ AL A +L+ + H+G G I+ +TDG
Sbjct: 353 DSIRDGK----VYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGK 408
Query: 373 VDTYDTIFAKYNWPDR-----KVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADV 427
+T K R +V IFT IG + F L+ ++ N G ++ D
Sbjct: 409 PTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFR-LLEKLSLENCGLTRRVHEEEDA 467
Query: 428 QENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQK 466
++ + + P + D D Y S++ QA K
Sbjct: 468 GSQLIGFYDEIRTPLLSDIRID------YPPSSVVQATK 500
>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 1 [Homo sapiens]
Length = 956
Score = 47.4 bits (111), Expect = 8e-05
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 17/219 (7%)
Query: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313
PK+VV ++D S SM G +L K + +IL L D F+II ++ + + L
Sbjct: 293 PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTP 352
Query: 314 QADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDF-NHTGQGSICSQAIMLITDGA 372
+ R K ++ + G ++ AL A +L+ + H+G G I+ +TDG
Sbjct: 353 DSIRDGK----VYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGK 408
Query: 373 VDTYDTIFAKYNWPDR-----KVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADV 427
+T K R +V IFT IG + F L+ ++ N G ++ D
Sbjct: 409 PTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFR-LLEKLSLENCGLTRRVHEEEDA 467
Query: 428 QENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQK 466
++ + + P + D D Y S++ QA K
Sbjct: 468 GSQLIGFYDEIRTPLLSDIRID------YPPSSVVQATK 500
>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 2 [Homo sapiens]
Length = 742
Score = 47.4 bits (111), Expect = 8e-05
Identities = 55/219 (25%), Positives = 93/219 (42%), Gaps = 17/219 (7%)
Query: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313
PK+VV ++D S SM G +L K + +IL L D F+II ++ + + L
Sbjct: 79 PKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQDRFSIIGFSNRIKVWKDHLISVTP 138
Query: 314 QADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDF-NHTGQGSICSQAIMLITDGA 372
+ R K ++ + G ++ AL A +L+ + H+G G I+ +TDG
Sbjct: 139 DSIRDGK----VYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGK 194
Query: 373 VDTYDTIFAKYNWPDR-----KVRIFTYLIGREAAFADNLKWMACANKGFFTQISTLADV 427
+T K R +V IFT IG + F L+ ++ N G ++ D
Sbjct: 195 PTVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFR-LLEKLSLENCGLTRRVHEEEDA 253
Query: 428 QENVMEYLHVLSRPKVIDQEHDVVWTEAYIDSTLPQAQK 466
++ + + P + D D Y S++ QA K
Sbjct: 254 GSQLIGFYDEIRTPLLSDIRID------YPPSSVVQATK 286
>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
Length = 911
Score = 43.9 bits (102), Expect = 8e-04
Identities = 45/203 (22%), Positives = 87/203 (42%), Gaps = 23/203 (11%)
Query: 255 KDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLVQ 314
K+VV ++D+SGSM+G ++ K+ + IL + D+F+++ + + G+LVQ
Sbjct: 291 KNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQ----SWKGSLVQ 346
Query: 315 ADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQ-----GSICSQAIMLI- 368
A N + ++ F +G LD A N +L Q + + A +LI
Sbjct: 347 ASEANLQAAQD-----FVRGFS-LDEATNLNGGLLRGIEILNQVQESLPELSNHASILIM 400
Query: 369 ------TDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFTQIS 422
T+G D + N + ++ G F + L+ M+ N G +I
Sbjct: 401 LTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDF-NFLEVMSMENNGRAQRIY 459
Query: 423 TLADVQENVMEYLHVLSRPKVID 445
D + + + +++P ++D
Sbjct: 460 EDHDATQQLQGFYSQVAKPLLVD 482
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 35.0 bits (79), Expect = 0.39
Identities = 27/101 (26%), Positives = 50/101 (49%), Gaps = 10/101 (9%)
Query: 52 EIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEM--FHKKSEAVRRL 109
++ K S + L+K+ K+ ++ EI+ L L +KL +N+EEM K+ + +RR+
Sbjct: 1838 DVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRV 1897
Query: 110 VEA--AEEAHLKHEF------DADLQYEYFNAVLINERDKD 142
E E LK D ++Q E A ++++ K+
Sbjct: 1898 EETLKLERDQLKESLQETKARDLEIQQELKTARMLSKEHKE 1938
>gi|4557353 branched chain keto acid dehydrogenase E1 beta precursor
[Homo sapiens]
Length = 392
Score = 33.9 bits (76), Expect = 0.86
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 22/123 (17%)
Query: 770 YRRAAEQIPGSFVYSIPFSTGPVNKSN----VVTASTSIQLLDERKSPVVAAVGIQMKLE 825
YR AAE++P Y+IP S V + +V T + ++ E S +G+
Sbjct: 244 YRAAAEEVPIE-PYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVS---- 298
Query: 826 FFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAV 885
C +D + I D +T+ C + G +L+S + TG F EI V
Sbjct: 299 ------------CEVIDLRTIIPWDVDTI-CKSVIKTGRLLISHEAPLTGGFASEISSTV 345
Query: 886 MNK 888
+
Sbjct: 346 QEE 348
>gi|34101272 branched chain keto acid dehydrogenase E1 beta
precursor [Homo sapiens]
Length = 392
Score = 33.9 bits (76), Expect = 0.86
Identities = 31/123 (25%), Positives = 50/123 (40%), Gaps = 22/123 (17%)
Query: 770 YRRAAEQIPGSFVYSIPFSTGPVNKSN----VVTASTSIQLLDERKSPVVAAVGIQMKLE 825
YR AAE++P Y+IP S V + +V T + ++ E S +G+
Sbjct: 244 YRAAAEEVPIE-PYNIPLSQAEVIQEGSDVTLVAWGTQVHVIREVASMAKEKLGVS---- 298
Query: 826 FFQRKFWTASRQCASLDGKCSISCDDETVNCYLIDNNGFILVSEDYTQTGDFFGEIEGAV 885
C +D + I D +T+ C + G +L+S + TG F EI V
Sbjct: 299 ------------CEVIDLRTIIPWDVDTI-CKSVIKTGRLLISHEAPLTGGFASEISSTV 345
Query: 886 MNK 888
+
Sbjct: 346 QEE 348
>gi|11321565 matrilin 3 precursor [Homo sapiens]
Length = 486
Score = 32.3 bits (72), Expect = 2.5
Identities = 40/164 (24%), Positives = 73/164 (44%), Gaps = 16/164 (9%)
Query: 254 PKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNIIAYNEELHYVEPCLNGTLV 313
P D+V ++D S S++ L T K VS I+DTL +A ++Y +
Sbjct: 81 PLDLVFIIDSSRSVRPLEFTKVKTFVSRIIDTLDIGPADTRVAV---VNYASTVKIEFQL 137
Query: 314 QADRTNKEHFREHLDKLFAKGIG-----MLDIALNEAFNILSDFNHTGQGSICSQAIMLI 368
QA T+K+ ++ + ++ G + A++EAF + + S + +++
Sbjct: 138 QA-YTDKQSLKQAVGRITPLSTGTMSGLAIQTAMDEAFTV--EAGAREPSSNIPKVAIIV 194
Query: 369 TDG-AVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMA 411
TDG D + + A+ + I Y +G + A +LK MA
Sbjct: 195 TDGRPQDQVNEVAAR----AQASGIELYAVGVDRADMASLKMMA 234
>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
transmembrane signal), 1 [Homo sapiens]
Length = 3259
Score = 32.3 bits (72), Expect = 2.5
Identities = 31/97 (31%), Positives = 45/97 (46%), Gaps = 8/97 (8%)
Query: 29 DVVRSEQQIPLSVVKL-WASAFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQL 87
+ V++E Q L + K A A K+ A S LL E + +A D L+L
Sbjct: 2046 EFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLA----DNLKL 2101
Query: 88 VKKLAKNMEEM---FHKKSEAVRRLVEAAEEAHLKHE 121
K+L N E + +K E + R +E AEE HLK +
Sbjct: 2102 KKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEK 2138
>gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
Length = 786
Score = 32.0 bits (71), Expect = 3.3
Identities = 49/206 (23%), Positives = 84/206 (40%), Gaps = 20/206 (9%)
Query: 249 QAATSPKDVVILVDVSGSMKG---------LRLTIAKQTVSSILDTLGDDDFFNIIAYNE 299
Q + + + + L+D SGSM+ LR+ AK+T+ +L +L +FNI +
Sbjct: 274 QPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGS 333
Query: 300 ELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGS 359
E C ++ +T +E KL +G +I L NI + G
Sbjct: 334 S---YEACFPESVKYTQQTMEEALGR--VKLMQADLGGTEI-LAPLQNIYRGPSIPGH-- 385
Query: 360 ICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFT 419
+ + TDG V ++ + +K R F++ IG E +K +A A+ G
Sbjct: 386 --PLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIG-EGTSTSLIKGIARASGGTSE 442
Query: 420 QISTLADVQENVMEYLHVLSRPKVID 445
I+ +Q + L +P V D
Sbjct: 443 FITGKDRMQSKALRTLKRSLQPVVED 468
>gi|38195080 BCSC-1 isoform 1 [Homo sapiens]
Length = 786
Score = 32.0 bits (71), Expect = 3.3
Identities = 49/206 (23%), Positives = 84/206 (40%), Gaps = 20/206 (9%)
Query: 249 QAATSPKDVVILVDVSGSMKG---------LRLTIAKQTVSSILDTLGDDDFFNIIAYNE 299
Q + + + + L+D SGSM+ LR+ AK+T+ +L +L +FNI +
Sbjct: 274 QPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGS 333
Query: 300 ELHYVEPCLNGTLVQADRTNKEHFREHLDKLFAKGIGMLDIALNEAFNILSDFNHTGQGS 359
E C ++ +T +E KL +G +I L NI + G
Sbjct: 334 S---YEACFPESVKYTQQTMEEALGR--VKLMQADLGGTEI-LAPLQNIYRGPSIPGH-- 385
Query: 360 ICSQAIMLITDGAVDTYDTIFAKYNWPDRKVRIFTYLIGREAAFADNLKWMACANKGFFT 419
+ + TDG V ++ + +K R F++ IG E +K +A A+ G
Sbjct: 386 --PLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIG-EGTSTSLIKGIARASGGTSE 442
Query: 420 QISTLADVQENVMEYLHVLSRPKVID 445
I+ +Q + L +P V D
Sbjct: 443 FITGKDRMQSKALRTLKRSLQPVVED 468
>gi|112789550 poly (ADP-ribose) polymerase family, member 4 [Homo
sapiens]
Length = 1724
Score = 31.6 bits (70), Expect = 4.3
Identities = 20/64 (31%), Positives = 30/64 (46%), Gaps = 4/64 (6%)
Query: 253 SPKDVVILVDVSGSMKGLRLTIAKQTVSSILDTLGDDDFFNII----AYNEELHYVEPCL 308
S +V+I +D S SM+G+ AKQ L +G+ NII Y E Y +
Sbjct: 873 SESEVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQKVNIIQFGTGYKELFSYPKHIT 932
Query: 309 NGTL 312
+ T+
Sbjct: 933 SNTM 936
>gi|156523968 poly (ADP-ribose) polymerase family, member 1 [Homo
sapiens]
Length = 1014
Score = 31.2 bits (69), Expect = 5.6
Identities = 38/189 (20%), Positives = 70/189 (37%), Gaps = 11/189 (5%)
Query: 507 KELLKTIPKYKLGIHGYAFAITNNGYILTHPELRLLYEEGKKRRKPNYSSVDLSEVEWED 566
K+ ++IPK L + + +G + ++ G R P+ SE+ W+D
Sbjct: 22 KKCSESIPKDSLRMAIMVQSPMFDGKVPHWYHFSCFWKVGHSIRHPDVEVDGFSELRWDD 81
Query: 567 RDDVLRNAMVNRKTGKFSMEVKKTVDKGKRVLVMTNDYYYTDIKGTPFSLGVALSRGHGK 626
+ V + A TGK + +K D+ K + +G +
Sbjct: 82 QQKVKKTAEAGGVTGKGQDGIGSKAEK------TLGDFAAEYAKSNR-----STCKGCME 130
Query: 627 YFFRGNVTIEEGLHDLEHPDVSLADEWSYCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQC 686
+G V + + + D E P + + D W + + + E LKG L
Sbjct: 131 KIEKGQVRLSKKMVDPEKPQLGMIDRWYHPGCFVKNREELGFRPEYSASQLKGFSLLATE 190
Query: 687 DKELIQEVL 695
DKE +++ L
Sbjct: 191 DKEALKKQL 199
>gi|40548332 coiled-coil domain containing 137 [Homo sapiens]
Length = 289
Score = 31.2 bits (69), Expect = 5.6
Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 28/134 (20%)
Query: 2 AGPGSPRRASRGASALLAAALLYAALGDVVRS--------------EQQIPLSVVKLWAS 47
AGPGSPRRA RG + A +RS EQ+IP + ++ S
Sbjct: 15 AGPGSPRRA-RGRQQVQPLGKQRPAPWPGLRSKEKKKVNCKPKNQDEQEIPFRLREIMRS 73
Query: 48 ------AFGGEIKSIAAKYSGSQLLQKKYKEYEKDVAIE-------EIDGLQLVKKLAKN 94
+ + AA+ + + L+K+ K E D+A+ E DG + + +
Sbjct: 74 RQEMKNPISNKKRKKAAQVTFRKTLEKEAKGEEPDIAVPKFKQRKGESDGAYIHRMQQEA 133
Query: 95 MEEMFHKKSEAVRR 108
+F K++A+R+
Sbjct: 134 QHVLFLSKNQAIRQ 147
>gi|56711320 hypothetical protein LOC145407 [Homo sapiens]
Length = 774
Score = 31.2 bits (69), Expect = 5.6
Identities = 22/71 (30%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 166 NISLSDVQVPTNMYNKDPAIVNGVYWSESLNKVFVDNFDRDPSLIWQYFGSAKGFFRQYP 225
N S++ Q P + ++DP +++ V + SLNK F N + P G A + P
Sbjct: 57 NSSVTSKQTPQLVVSEDPMMMSAVPSATSLNKAFSINKETQP-------GQAGLMQTERP 109
Query: 226 GIKWEPDENGV 236
G+ P E+GV
Sbjct: 110 GVS-TPTESGV 119
>gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]
Length = 340
Score = 30.8 bits (68), Expect = 7.3
Identities = 17/52 (32%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 55 SIAAKYSGSQLLQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEEMFHKKSEAV 106
+++ S L+KK ++ EK+V E + L+LV +L ++ EEM K E +
Sbjct: 257 NVSGTLVSSSTLEKKIEDLEKEVVRERQENLRLV-RLMQDKEEMIGKLKEEI 307
>gi|13375985 zinc finger, AN1-type domain 1 [Homo sapiens]
Length = 268
Score = 30.8 bits (68), Expect = 7.3
Identities = 24/104 (23%), Positives = 44/104 (42%), Gaps = 8/104 (7%)
Query: 655 YCNTDLHPEHRHLSQLEAIKLYLKGKEPLLQCDKELIQEVLFDAVVSAPIEAYWTSLALN 714
YC + HRH S E KL + +P + ++L+++++ D+ W
Sbjct: 81 YCEKNFCLRHRHQSDHECEKLEI--PKPRMAATQKLVKDII-DSKTGETASKRWKG---- 133
Query: 715 KSENSDKGVEVAFLGTRTGLSRINLFVGAEQLTNQDFLKAGDKE 758
++NS+ +VA + + E++ Q FL G KE
Sbjct: 134 -AKNSETAAKVALMKLKMHADGDKSLPQTERIYFQVFLPKGSKE 176
>gi|239755047 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 30.4 bits (67), Expect = 9.5
Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 66 LQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEE---MFHKKSEAVRRLV---EAAEEAHLK 119
+Q+K ++ EKD + E + L L + K+M E + KSE R V E EE HL+
Sbjct: 891 VQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQ 950
Query: 120 HEFDADLQYEYFN 132
+ + + Q E N
Sbjct: 951 KQAEYEKQLEQLN 963
>gi|239749578 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1002
Score = 30.4 bits (67), Expect = 9.5
Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 66 LQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEE---MFHKKSEAVRRLV---EAAEEAHLK 119
+Q+K ++ EKD + E + L L + K+M E + KSE R V E EE HL+
Sbjct: 784 VQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQ 843
Query: 120 HEFDADLQYEYFN 132
+ + + Q E N
Sbjct: 844 KQAEYEKQLEQLN 856
>gi|239743724 PREDICTED: ankyrin repeat domain 18A [Homo sapiens]
Length = 1415
Score = 30.4 bits (67), Expect = 9.5
Identities = 24/73 (32%), Positives = 37/73 (50%), Gaps = 6/73 (8%)
Query: 66 LQKKYKEYEKDVAIEEIDGLQLVKKLAKNMEE---MFHKKSEAVRRLV---EAAEEAHLK 119
+Q+K ++ EKD + E + L L + K+M E + KSE R V E EE HL+
Sbjct: 891 VQEKCEKLEKDKKMLEEEVLNLKTHMEKDMVELGKLQEYKSELDERAVQEIEKLEEIHLQ 950
Query: 120 HEFDADLQYEYFN 132
+ + + Q E N
Sbjct: 951 KQAEYEKQLEQLN 963
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,371,042
Number of Sequences: 37866
Number of extensions: 1720697
Number of successful extensions: 4509
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 4443
Number of HSP's gapped (non-prelim): 50
length of query: 1091
length of database: 18,247,518
effective HSP length: 113
effective length of query: 978
effective length of database: 13,968,660
effective search space: 13661349480
effective search space used: 13661349480
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.