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Search of human proteins with 54112119
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|54112119 splicing factor 3b, subunit 1 isoform 2 [Homo
sapiens]
(144 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|54112119 splicing factor 3b, subunit 1 isoform 2 [Homo sapiens] 293 4e-80
gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens] 283 4e-77
gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens] 30 0.70
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 29 1.2
gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Hom... 29 1.2
gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Hom... 29 1.2
gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo sapiens] 28 2.7
gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo sapiens] 28 2.7
gi|226246554 hypothetical protein LOC643677 [Homo sapiens] 28 3.5
gi|27262659 colony stimulating factor 1 receptor precursor [Homo... 28 3.5
gi|12083581 phosphoinositide-specific phospholipase C beta 1 iso... 28 3.5
gi|33356544 phosphoinositide-specific phospholipase C beta 1 iso... 28 3.5
gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sap... 28 3.5
gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sap... 28 3.5
gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sap... 28 3.5
gi|32483399 p21-activated kinase 2 [Homo sapiens] 27 4.5
gi|239754744 PREDICTED: similar to hCG2043257 [Homo sapiens] 27 4.5
gi|38788260 bromodomain PHD finger transcription factor isoform ... 27 4.5
gi|38788274 bromodomain PHD finger transcription factor isoform ... 27 4.5
gi|216548564 hypothetical protein LOC51093 isoform 2 [Homo sapiens] 27 4.5
gi|216548560 hypothetical protein LOC51093 isoform 1 [Homo sapiens] 27 4.5
gi|61676195 zinc finger protein 320 [Homo sapiens] 27 4.5
gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 famil... 27 5.9
gi|239747524 PREDICTED: similar to serum response factor-related... 27 5.9
gi|5174409 CD2 antigen (cytoplasmic tail) binding protein 2 [Hom... 27 5.9
gi|24308039 hypothetical protein LOC23376 [Homo sapiens] 27 7.7
>gi|54112119 splicing factor 3b, subunit 1 isoform 2 [Homo sapiens]
Length = 144
Score = 293 bits (749), Expect = 4e-80
Identities = 144/144 (100%), Positives = 144/144 (100%)
Query: 1 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA 60
MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
Sbjct: 1 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA 60
Query: 61 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK 120
TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
Sbjct: 61 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK 120
Query: 121 KHRRTMIISPERLDPFADGFYSAA 144
KHRRTMIISPERLDPFADGFYSAA
Sbjct: 121 KHRRTMIISPERLDPFADGFYSAA 144
>gi|54112117 splicing factor 3b, subunit 1 isoform 1 [Homo sapiens]
Length = 1304
Score = 283 bits (724), Expect = 4e-77
Identities = 139/139 (100%), Positives = 139/139 (100%)
Query: 1 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA 60
MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA
Sbjct: 1 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA 60
Query: 61 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK 120
TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK
Sbjct: 61 TELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYK 120
Query: 121 KHRRTMIISPERLDPFADG 139
KHRRTMIISPERLDPFADG
Sbjct: 121 KHRRTMIISPERLDPFADG 139
>gi|187937179 apoptosis-associated tyrosine kinase [Homo sapiens]
Length = 1374
Score = 30.0 bits (66), Expect = 0.70
Identities = 22/69 (31%), Positives = 31/69 (44%), Gaps = 4/69 (5%)
Query: 46 GSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALL----NDIPQSTEQY 101
G D AG S AT +DDD D S++ SL + G+ PV + + P+ +
Sbjct: 542 GHDPDCAGCAPSPPATADQDDDSDGSTAASLAMEPLLGHGPPVDVPWGRGDHYPRRSLAR 601
Query: 102 DPFAEHRPP 110
DP R P
Sbjct: 602 DPLCPSRSP 610
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 29.3 bits (64), Expect = 1.2
Identities = 17/56 (30%), Positives = 27/56 (48%), Gaps = 6/56 (10%)
Query: 32 GLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAP 87
GL+ Y +YG + R G V+++ T ++D D+ S T +PG AP
Sbjct: 2468 GLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPT------EPGTEAP 2517
Score = 26.9 bits (58), Expect = 5.9
Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 6/69 (8%)
Query: 14 QIREIQGKKAAL------DEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDD 67
Q ++ QG+ A+ +E GLD Y +YG + G + +A T ++D
Sbjct: 1294 QYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDV 1353
Query: 68 DDYSSSTSL 76
D+ S T L
Sbjct: 1354 DETPSPTEL 1362
Score = 26.9 bits (58), Expect = 5.9
Identities = 14/48 (29%), Positives = 23/48 (47%)
Query: 32 GLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQ 79
GL+ Y +YG + R G V+++ T E++ D + LGQ
Sbjct: 2152 GLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQ 2199
>gi|189217915 syntaxin binding protein 5 (tomosyn) isoform b [Homo
sapiens]
Length = 1151
Score = 29.3 bits (64), Expect = 1.2
Identities = 13/42 (30%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 101 YDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGFYS 142
Y+P+ EH P+ D +++ KK RR + +SP ++ Y+
Sbjct: 875 YEPWREHNVPEEKDEKEKLKK-RRPVSVSPSSSQEISENQYA 915
>gi|189217897 syntaxin binding protein 5 (tomosyn) isoform a [Homo
sapiens]
Length = 1115
Score = 29.3 bits (64), Expect = 1.2
Identities = 13/42 (30%), Positives = 24/42 (57%), Gaps = 1/42 (2%)
Query: 101 YDPFAEHRPPKIADREDEYKKHRRTMIISPERLDPFADGFYS 142
Y+P+ EH P+ D +++ KK RR + +SP ++ Y+
Sbjct: 839 YEPWREHNVPEEKDEKEKLKK-RRPVSVSPSSSQEISENQYA 879
>gi|61742777 leucyl/cystinyl aminopeptidase isoform 1 [Homo
sapiens]
Length = 1025
Score = 28.1 bits (61), Expect = 2.7
Identities = 11/24 (45%), Positives = 16/24 (66%)
Query: 55 VTSIAATELEDDDDDYSSSTSLLG 78
V + E+E+D++DY SS LLG
Sbjct: 55 VRGLGEHEMEEDEEDYESSAKLLG 78
>gi|61742775 leucyl/cystinyl aminopeptidase isoform 2 [Homo
sapiens]
Length = 1011
Score = 28.1 bits (61), Expect = 2.7
Identities = 11/24 (45%), Positives = 16/24 (66%)
Query: 55 VTSIAATELEDDDDDYSSSTSLLG 78
V + E+E+D++DY SS LLG
Sbjct: 41 VRGLGEHEMEEDEEDYESSAKLLG 64
>gi|226246554 hypothetical protein LOC643677 [Homo sapiens]
Length = 7081
Score = 27.7 bits (60), Expect = 3.5
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 64 EDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQ---YDPFAEHRPPKIADREDEYK 120
EDD+ S+ ++ + G A AL D+P +T++ D A+ + + + E++ K
Sbjct: 4156 EDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGK 4215
Query: 121 KHRR 124
+ RR
Sbjct: 4216 EDRR 4219
>gi|27262659 colony stimulating factor 1 receptor precursor [Homo
sapiens]
Length = 972
Score = 27.7 bits (60), Expect = 3.5
Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 2/41 (4%)
Query: 103 PFAEHRP-PKIADREDEYKKHRRTMIISPERLDPFADGFYS 142
PF++H+P PK+A+ + +R T +S RL P G YS
Sbjct: 341 PFSDHQPEPKLANATTK-DTYRHTFTLSLPRLKPSEAGRYS 380
>gi|12083581 phosphoinositide-specific phospholipase C beta 1
isoform a [Homo sapiens]
Length = 1216
Score = 27.7 bits (60), Expect = 3.5
Identities = 22/86 (25%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA 60
M KI ++ + E GKK ++A DS+ ++ G + A
Sbjct: 459 MYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGE----------AD 508
Query: 61 TELEDDDDDYSSSTSLLGQKKPGYHA 86
TE +DDDDD S + + G A
Sbjct: 509 TESDDDDDDDDCKKSSMDEGTAGSEA 534
>gi|33356544 phosphoinositide-specific phospholipase C beta 1
isoform b [Homo sapiens]
Length = 1173
Score = 27.7 bits (60), Expect = 3.5
Identities = 22/86 (25%), Positives = 34/86 (39%), Gaps = 10/86 (11%)
Query: 1 MAKIAKTHEDIEAQIREIQGKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAA 60
M KI ++ + E GKK ++A DS+ ++ G + A
Sbjct: 459 MYKILVKNKKKSHKSSEGSGKKKLSEQASNTYSDSSSMFEPSSPGAGE----------AD 508
Query: 61 TELEDDDDDYSSSTSLLGQKKPGYHA 86
TE +DDDDD S + + G A
Sbjct: 509 TESDDDDDDDDCKKSSMDEGTAGSEA 534
>gi|239756039 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
Length = 6929
Score = 27.7 bits (60), Expect = 3.5
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 64 EDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQ---YDPFAEHRPPKIADREDEYK 120
EDD+ S+ ++ + G A AL D+P +T++ D A+ + + + E++ K
Sbjct: 4085 EDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGK 4144
Query: 121 KHRR 124
+ RR
Sbjct: 4145 EDRR 4148
>gi|239750569 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
Length = 6929
Score = 27.7 bits (60), Expect = 3.5
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 64 EDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQ---YDPFAEHRPPKIADREDEYK 120
EDD+ S+ ++ + G A AL D+P +T++ D A+ + + + E++ K
Sbjct: 4085 EDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGK 4144
Query: 121 KHRR 124
+ RR
Sbjct: 4145 EDRR 4148
>gi|239744870 PREDICTED: hypothetical protein LOC643677 [Homo sapiens]
Length = 6929
Score = 27.7 bits (60), Expect = 3.5
Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 64 EDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQ---YDPFAEHRPPKIADREDEYK 120
EDD+ S+ ++ + G A AL D+P +T++ D A+ + + + E++ K
Sbjct: 4085 EDDEVKISAKKDIMHPEDKGLKAKKALSQDLPLNTKEPGKMDQEAQEQGKEDREGEEQGK 4144
Query: 121 KHRR 124
+ RR
Sbjct: 4145 EDRR 4148
>gi|32483399 p21-activated kinase 2 [Homo sapiens]
Length = 524
Score = 27.3 bits (59), Expect = 4.5
Identities = 21/65 (32%), Positives = 26/65 (40%), Gaps = 9/65 (13%)
Query: 66 DDDDYSSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRRT 125
+ D + S T L K G AP + TE+ D E PP IA R D K
Sbjct: 146 EKDGFPSGTPALNAK--GTEAPAVV-------TEEEDDDEETAPPVIAPRPDHTKSIYTR 196
Query: 126 MIISP 130
+I P
Sbjct: 197 SVIDP 201
>gi|239754744 PREDICTED: similar to hCG2043257 [Homo sapiens]
Length = 132
Score = 27.3 bits (59), Expect = 4.5
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 20 GKKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQ 79
GKK L+ +Q +G D +Y Q+ G + Y + +TE D SS S + +
Sbjct: 35 GKKITLECSQTMGHDKMYWYQQD--PGMELHLIHYSYGVNSTEKGD-----LSSESTVSR 87
Query: 80 KKPGYHAPVALLNDIPQSTEQY 101
+ H P+ L + P T QY
Sbjct: 88 IRT-EHFPLTLESARPSHTSQY 108
>gi|38788260 bromodomain PHD finger transcription factor isoform 2
[Homo sapiens]
Length = 2903
Score = 27.3 bits (59), Expect = 4.5
Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 14/48 (29%)
Query: 62 ELEDDDDD-----------YSSSTSLLGQKKPGYH---APVALLNDIP 95
E+EDDDDD +S+ +S G++KP H +P+ DIP
Sbjct: 178 EMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIP 225
>gi|38788274 bromodomain PHD finger transcription factor isoform 1
[Homo sapiens]
Length = 2920
Score = 27.3 bits (59), Expect = 4.5
Identities = 17/48 (35%), Positives = 25/48 (52%), Gaps = 14/48 (29%)
Query: 62 ELEDDDDD-----------YSSSTSLLGQKKPGYH---APVALLNDIP 95
E+EDDDDD +S+ +S G++KP H +P+ DIP
Sbjct: 178 EMEDDDDDASYCTESSFRSHSTYSSTPGRRKPRVHRPRSPILEEKDIP 225
>gi|216548564 hypothetical protein LOC51093 isoform 2 [Homo sapiens]
Length = 277
Score = 27.3 bits (59), Expect = 4.5
Identities = 13/41 (31%), Positives = 21/41 (51%)
Query: 71 SSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPK 111
S++ +L + PG+ P L + QS+ PF +H PK
Sbjct: 93 STACALAFTRMPGFQTPSEFLENPSQSSRLTAPFRKHVRPK 133
>gi|216548560 hypothetical protein LOC51093 isoform 1 [Homo sapiens]
Length = 475
Score = 27.3 bits (59), Expect = 4.5
Identities = 13/41 (31%), Positives = 21/41 (51%)
Query: 71 SSSTSLLGQKKPGYHAPVALLNDIPQSTEQYDPFAEHRPPK 111
S++ +L + PG+ P L + QS+ PF +H PK
Sbjct: 93 STACALAFTRMPGFQTPSEFLENPSQSSRLTAPFRKHVRPK 133
>gi|61676195 zinc finger protein 320 [Homo sapiens]
Length = 509
Score = 27.3 bits (59), Expect = 4.5
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 4/94 (4%)
Query: 33 LDSTGYYDQE-IYGGSDSRFAGY-VTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVAL 90
L STG + E I+ G+ R A Y + + + E+E D D+ + + AP+
Sbjct: 58 LSSTGQGNTEVIHTGTLQRQASYHIGAFCSQEIEKDIHDFVFQWQ--EDETNDHEAPMTE 115
Query: 91 LNDIPQSTEQYDPFAEHRPPKIADREDEYKKHRR 124
+ + ST++YD P E + H R
Sbjct: 116 IKKLTSSTDRYDQRHAGNKPIKGQLESRFHLHLR 149
>gi|5453880 acidic (leucine-rich) nuclear phosphoprotein 32 family,
member A [Homo sapiens]
Length = 249
Score = 26.9 bits (58), Expect = 5.9
Identities = 17/80 (21%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 39 YDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPGYHAPVALLNDIPQST 98
YD++ DS GYV + E ++D+++Y ++ ++ D+ S
Sbjct: 148 YDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYDEDAQVVEDEEDEDEEEEGEEEDV--SG 205
Query: 99 EQYDPFAEHRPPKIADREDE 118
E+ + + ++ D EDE
Sbjct: 206 EEEEDEEGYNDGEVDDEEDE 225
>gi|239747524 PREDICTED: similar to serum response factor-related
protein C4 [Homo sapiens]
Length = 434
Score = 26.9 bits (58), Expect = 5.9
Identities = 16/56 (28%), Positives = 26/56 (46%)
Query: 28 AQGVGLDSTGYYDQEIYGGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQKKPG 83
+QG G +G Y+ GG S G +S + +D +Y++ +S G K G
Sbjct: 83 SQGSGYGGSGSYNSYNNGGGGSFGGGSGSSFGGSGSYNDFGNYNNQSSNFGPTKGG 138
>gi|5174409 CD2 antigen (cytoplasmic tail) binding protein 2 [Homo
sapiens]
Length = 341
Score = 26.9 bits (58), Expect = 5.9
Identities = 16/36 (44%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 45 GGSDSRFAGYVTSIAATELEDDDDDYSSSTSLLGQK 80
GG SRF G S+ + E EDDDD SS +L +
Sbjct: 35 GGPGSRFKG-KHSLDSDEEEDDDDGGSSKYDILASE 69
>gi|24308039 hypothetical protein LOC23376 [Homo sapiens]
Length = 794
Score = 26.6 bits (57), Expect = 7.7
Identities = 23/81 (28%), Positives = 36/81 (44%), Gaps = 10/81 (12%)
Query: 7 THEDIEAQIREIQG----KKAALDEAQGVGLDSTGYYDQEIYGGSDSRFAGY-VTSIAAT 61
T ED++ QI ++ KK DE + + +G + GG Y + +
Sbjct: 397 TEEDLK-QISTLESVSTSKKDKKDERRRKATEGSG----SMRGGGGGNAREYKIKKVKKK 451
Query: 62 ELEDDDDDYSSSTSLLGQKKP 82
+DDD D S +S G+KKP
Sbjct: 452 GRKDDDSDDESQSSHTGKKKP 472
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,772,950
Number of Sequences: 37866
Number of extensions: 254262
Number of successful extensions: 649
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 629
Number of HSP's gapped (non-prelim): 38
length of query: 144
length of database: 18,247,518
effective HSP length: 92
effective length of query: 52
effective length of database: 14,763,846
effective search space: 767719992
effective search space used: 767719992
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.