Search of human proteins with 53829365

Search of human proteins with 53829365

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|53829365 potassium channel tetramerisation domain containing
2 [Homo sapiens]
         (263 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|53829365 potassium channel tetramerisation domain containing ...   540   e-154
gi|9506651 potassium channel tetramerisation domain containing 5...   333   7e-92
gi|169234778 potassium channel tetramerisation domain containing...   287   6e-78
gi|39753959 potassium channel tetramerisation domain containing ...    95   5e-20
gi|169184031 PREDICTED: similar to potassium channel tetramerisa...    86   3e-17
gi|169179790 PREDICTED: similar to potassium channel tetramerisa...    86   3e-17
gi|169180181 PREDICTED: similar to potassium channel tetramerisa...    86   3e-17
gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]                  83   2e-16
gi|46255026 potassium channel tetramerisation domain containing ...    76   3e-14
gi|142356950 potassium channel tetramerisation domain containing...    62   5e-10
gi|19923973 potassium channel tetramerisation domain containing ...    62   7e-10
gi|38198663 potassium channel tetramerisation domain containing ...    61   9e-10
gi|146198864 potassium channel tetramerisation domain containing...    61   9e-10
gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo...    60   1e-09
gi|24497460 Shaw-related voltage-gated potassium channel protein...    59   3e-09
gi|13994353 potassium channel tetramerisation domain containing ...    58   7e-09
gi|55926200 potassium channel tetramerisation domain containing ...    58   7e-09
gi|189571693 potassium channel tetramerisation domain containing...    55   6e-08
gi|189571691 potassium channel tetramerisation domain containing...    55   6e-08
gi|30578412 potassium channel tetramerisation domain containing ...    55   6e-08
gi|71143104 potassium channel tetramerisation domain containing ...    54   1e-07
gi|194018443 potassium channel tetramerisation domain containing...    54   2e-07
gi|194018441 potassium channel tetramerisation domain containing...    54   2e-07
gi|194018439 potassium channel tetramerisation domain containing...    54   2e-07
gi|27436981 potassium voltage-gated channel, Shal-related subfam...    51   9e-07
gi|23308551 potassium channel tetramerisation domain containing ...    51   1e-06
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    50   2e-06
gi|9789987 potassium voltage-gated channel, Shal-related subfami...    50   3e-06
gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]       50   3e-06
gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]       50   3e-06

>gi|53829365 potassium channel tetramerisation domain containing 2
           [Homo sapiens]
          Length = 263

 Score =  540 bits (1391), Expect = e-154
 Identities = 263/263 (100%), Positives = 263/263 (100%)

Query: 1   MAELQLDPAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPG 60
           MAELQLDPAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPG
Sbjct: 1   MAELQLDPAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPG 60

Query: 61  PPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYL 120
           PPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYL
Sbjct: 61  PPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYL 120

Query: 121 IDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQ 180
           IDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQ
Sbjct: 121 IDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQ 180

Query: 181 GPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNN 240
           GPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNN
Sbjct: 181 GPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNN 240

Query: 241 STNGIVIEPSEKAKILQERGSRM 263
           STNGIVIEPSEKAKILQERGSRM
Sbjct: 241 STNGIVIEPSEKAKILQERGSRM 263


>gi|9506651 potassium channel tetramerisation domain containing 5
           [Homo sapiens]
          Length = 234

 Score =  333 bits (855), Expect = 7e-92
 Identities = 161/196 (82%), Positives = 181/196 (92%), Gaps = 1/196 (0%)

Query: 68  GGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTY 127
           G  ++WVRLNVGGTYF+TTRQTL R+PKSFL RLC Q DP+LDSDKDETGAYLIDRDPTY
Sbjct: 40  GSVSKWVRLNVGGTYFLTTRQTLCRDPKSFLYRLC-QADPDLDSDKDETGAYLIDRDPTY 98

Query: 128 FGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPVKHVY 187
           FGP+LNYLRHGKL+I K+LAEEGVLEEAEFYNI SL++LVK++IR+ +++TSQ PVKHVY
Sbjct: 99  FGPVLNYLRHGKLVINKDLAEEGVLEEAEFYNITSLIKLVKDKIRERDSKTSQVPVKHVY 158

Query: 188 RVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQAEFLCVVSRELNNSTNGIVI 247
           RVLQCQEEELTQMVSTMSDGWKFEQL+SIGSSYNYGNEDQAEFLCVVS+EL+N+  G   
Sbjct: 159 RVLQCQEEELTQMVSTMSDGWKFEQLVSIGSSYNYGNEDQAEFLCVVSKELHNTPYGTAS 218

Query: 248 EPSEKAKILQERGSRM 263
           EPSEKAKILQERGSRM
Sbjct: 219 EPSEKAKILQERGSRM 234


>gi|169234778 potassium channel tetramerisation domain containing 17
           [Homo sapiens]
          Length = 297

 Score =  287 bits (735), Expect = 6e-78
 Identities = 144/212 (67%), Positives = 172/212 (81%), Gaps = 6/212 (2%)

Query: 52  AQPLEPGPG-PPERAGG---GGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP 107
           A  +E G   PP  AGG   GG  +WVRLNVGGT F+TTRQTL RE KSFL RLC  E  
Sbjct: 7   AMRMEAGEAAPPAGAGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGE-- 64

Query: 108 ELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLV 167
           EL SD+DETGAYLIDRDPTYFGPILN+LRHGKL++ K++AEEGVLEEAEFYNI  L+R++
Sbjct: 65  ELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRII 124

Query: 168 KERIRDNENRTSQGPVKHVYRVLQCQEEELTQMVSTMSDGWKFEQLISIGSSYNYGNEDQ 227
           K+R+ + +   +Q P KHVYRVLQCQEEELTQMVSTMSDGW+FEQL++IGSSYNYG+EDQ
Sbjct: 125 KDRMEEKDYTVTQVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQLVNIGSSYNYGSEDQ 184

Query: 228 AEFLCVVSRELNNSTNGIVIEPSEKAKILQER 259
           AEFLCVVS+EL+++ NG+  E S K K  +E+
Sbjct: 185 AEFLCVVSKELHSTPNGLSSESSRKTKSTEEQ 216


>gi|39753959 potassium channel tetramerisation domain containing 9
           [Homo sapiens]
          Length = 389

 Score = 95.1 bits (235), Expect = 5e-20
 Identities = 50/112 (44%), Positives = 70/112 (62%), Gaps = 2/112 (1%)

Query: 73  WVRLNVGGTYFVTTRQTL-GREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPI 131
           W+ LNVGG YF TTR TL  +EP S L  +  ++     + +D  GA+LIDR P YF PI
Sbjct: 90  WLTLNVGGRYFTTTRSTLVNKEPDSMLAHMF-KDKGVWGNKQDHRGAFLIDRSPEYFEPI 148

Query: 132 LNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPV 183
           LNYLRHG+LI+   +   GVLEEA F+ I SL+  ++  I++++      P+
Sbjct: 149 LNYLRHGQLIVNDGINLLGVLEEARFFGIDSLIEHLEVAIKNSQPPEDHSPI 200


>gi|169184031 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 47/112 (41%), Positives = 68/112 (60%), Gaps = 2/112 (1%)

Query: 73  WVRLNVGGTYFVTTRQTL-GREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPI 131
           W+ L+VGG YF TT  TL  +EP   L  +  ++     + +D  GA+LID+ P YF PI
Sbjct: 90  WLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF-KDKGVWGNKQDHRGAFLIDQSPEYFEPI 148

Query: 132 LNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPV 183
           LNYLRHG+LI+   +   GVLEEA F+ I SL+  +K  I++++      P+
Sbjct: 149 LNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPI 200


>gi|169179790 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 47/112 (41%), Positives = 68/112 (60%), Gaps = 2/112 (1%)

Query: 73  WVRLNVGGTYFVTTRQTL-GREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPI 131
           W+ L+VGG YF TT  TL  +EP   L  +  ++     + +D  GA+LID+ P YF PI
Sbjct: 90  WLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF-KDKGVWGNKQDHRGAFLIDQSPEYFEPI 148

Query: 132 LNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPV 183
           LNYLRHG+LI+   +   GVLEEA F+ I SL+  +K  I++++      P+
Sbjct: 149 LNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPI 200


>gi|169180181 PREDICTED: similar to potassium channel
           tetramerisation domain containing 9 [Homo sapiens]
          Length = 261

 Score = 86.3 bits (212), Expect = 3e-17
 Identities = 47/112 (41%), Positives = 68/112 (60%), Gaps = 2/112 (1%)

Query: 73  WVRLNVGGTYFVTTRQTL-GREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPI 131
           W+ L+VGG YF TT  TL  +EP   L  +  ++     + +D  GA+LID+ P YF PI
Sbjct: 90  WLTLHVGGQYFTTTWSTLVNKEPDIMLAHMF-KDKGVWGNKQDHRGAFLIDQSPEYFEPI 148

Query: 132 LNYLRHGKLIITKELAEEGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPV 183
           LNYLRHG+LI+   +   GVLEEA F+ I SL+  +K  I++++      P+
Sbjct: 149 LNYLRHGQLIVNDGIDLLGVLEEARFFGIDSLIEHLKVAIKNSQPPEDHLPI 200


>gi|223005950 SH3KBP1 binding protein 1 [Homo sapiens]
          Length = 707

 Score = 83.2 bits (204), Expect = 2e-16
 Identities = 61/141 (43%), Positives = 74/141 (52%), Gaps = 24/141 (17%)

Query: 48  AAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP 107
           AAA A    P  GPP           + LNVGG  F T+RQTL   P SF   L      
Sbjct: 3   AAATAAEGVPSRGPPGEV--------IHLNVGGKRFSTSRQTLTWIPDSFFSSLL---SG 51

Query: 108 ELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGV-----LEEAEFYNIAS 162
            + + KDETGA  IDRDPT F PILN+LR      TKEL   GV     L EA+FY +  
Sbjct: 52  RISTLKDETGAIFIDRDPTVFAPILNFLR------TKELDPRGVHGSSLLHEAQFYGLTP 105

Query: 163 LVRLVKERIRDNENRTSQGPV 183
           LVR  + ++R+  +R+S G V
Sbjct: 106 LVR--RLQLREELDRSSCGNV 124


>gi|46255026 potassium channel tetramerisation domain containing 3
           [Homo sapiens]
          Length = 815

 Score = 76.3 bits (186), Expect = 3e-14
 Identities = 51/106 (48%), Positives = 58/106 (54%), Gaps = 14/106 (13%)

Query: 65  AGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRD 124
           A   G+   V+LNVGGT F T+RQTL   P SF   L       + + +DETGA  IDRD
Sbjct: 11  AAAAGSGEIVQLNVGGTRFSTSRQTLMWIPDSFFSSLL---SGRISTLRDETGAIFIDRD 67

Query: 125 PTYFGPILNYLRHGKLIITKELAEEGV-----LEEAEFYNIASLVR 165
           P  F PILN+LR      TKEL   GV       EAEFY I  LVR
Sbjct: 68  PAAFAPILNFLR------TKELDLRGVSINVLRHEAEFYGITPLVR 107


>gi|142356950 potassium channel tetramerisation domain containing 14
           [Homo sapiens]
          Length = 255

 Score = 62.0 bits (149), Expect = 5e-10
 Identities = 45/125 (36%), Positives = 62/125 (49%), Gaps = 12/125 (9%)

Query: 45  GRPAAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQ 104
           GR  +    P  P P  P  +        V LNVGG +  TT  TL + P S L  +   
Sbjct: 12  GRMTSQTPLPQSPRPRRPTMS------TVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSS 65

Query: 105 EDPELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLV 164
                 +  D  G + IDR  TYF PIL+YLR G+ + T+ + E  V  EA+FY I  LV
Sbjct: 66  L---AKASTDAEGRFFIDRPSTYFRPILDYLRTGQ-VPTQHIPE--VYREAQFYEIKPLV 119

Query: 165 RLVKE 169
           +L+++
Sbjct: 120 KLLED 124


>gi|19923973 potassium channel tetramerisation domain containing 12
           [Homo sapiens]
          Length = 325

 Score = 61.6 bits (148), Expect = 7e-10
 Identities = 42/120 (35%), Positives = 60/120 (50%), Gaps = 15/120 (12%)

Query: 60  GPPERAGGGGAARW-------------VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQED 106
           G P   GGGG +               V LNVGG  +VT R T+   P S L R+  Q+ 
Sbjct: 9   GLPNGGGGGGGSGSSSSSAEPPLFPDIVELNVGGQVYVTRRCTVVSVPDSLLWRMFTQQQ 68

Query: 107 PELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLE-EAEFYNIASLVR 165
           P+ +  +D  G + +DRD   F  IL+YLR  +L++     E   L+ EAE++ +  LVR
Sbjct: 69  PQ-ELARDSKGRFFLDRDGFLFRYILDYLRDLQLVLPDYFPERSRLQREAEYFELPELVR 127


>gi|38198663 potassium channel tetramerisation domain containing 8
           [Homo sapiens]
          Length = 473

 Score = 61.2 bits (147), Expect = 9e-10
 Identities = 50/174 (28%), Positives = 71/174 (40%), Gaps = 27/174 (15%)

Query: 15  GGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGGGGAARWV 74
           G GGS +      V    SP          G  AAA   P  P P P            V
Sbjct: 7   GSGGSTILPISEMVSSSSSP----------GASAAAAPGPCAPSPFPEV----------V 46

Query: 75  RLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDS------DKDETGAYLIDRDPTYF 128
            LNVGG  +VT   TL   P S L  +     P   +       +D    + IDRD   F
Sbjct: 47  ELNVGGQVYVTKHSTLLSVPDSTLASMFSPSSPRGGARRRGELPRDSRARFFIDRDGFLF 106

Query: 129 GPILNYLRHGKLIITKELAE-EGVLEEAEFYNIASLVRLVKERIRDNENRTSQG 181
             +L+YLR  +L + +   E E +L EAE++ +  LV+L+  ++    +   +G
Sbjct: 107 RYVLDYLRDKQLALPEHFPEKERLLREAEYFQLTDLVKLLSPKVTKQNSLNDEG 160


>gi|146198864 potassium channel tetramerisation domain containing 4
           [Homo sapiens]
          Length = 259

 Score = 61.2 bits (147), Expect = 9e-10
 Identities = 36/96 (37%), Positives = 56/96 (58%), Gaps = 4/96 (4%)

Query: 76  LNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILNYL 135
           LNVGG  ++T +QTL + P +FL  +    + ++    D  G Y IDRD   F  +LN+L
Sbjct: 37  LNVGGYLYITQKQTLTKYPDTFLEGIV---NGKILCPFDADGHYFIDRDGLLFRHVLNFL 93

Query: 136 RHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKER 170
           R+G+L++ +   E  +L +EAEF+ +  L   VK R
Sbjct: 94  RNGELLLPEGFRENQLLAQEAEFFQLKGLAEEVKSR 129


>gi|10863937 tumor necrosis factor, alpha-induced protein 1 [Homo
           sapiens]
          Length = 316

 Score = 60.5 bits (145), Expect = 1e-09
 Identities = 42/132 (31%), Positives = 70/132 (53%), Gaps = 7/132 (5%)

Query: 66  GGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDP 125
           GGG   ++V+LNVGG+ + TT + L R        L       ++   D+ G  LIDR  
Sbjct: 22  GGGLGNKYVQLNVGGSLYYTTVRALTRHDTM----LKAMFSGRMEVLTDKEGWILIDRCG 77

Query: 126 TYFGPILNYLRHGKLIITKELAE-EGVLEEAEFYNIASLVRLVKERIRDNENRTSQGPVK 184
            +FG ILNYLR   + + +   E + ++ EA++Y I  LV + +  ++D ++  S  PV 
Sbjct: 78  KHFGTILNYLRDDTITLPQNRQEIKELMAEAKYYLIQGLVNMCQSALQDKKD--SYQPVC 135

Query: 185 HVYRVLQCQEEE 196
           ++  +   +EEE
Sbjct: 136 NIPIITSLKEEE 147


>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
           [Homo sapiens]
          Length = 757

 Score = 59.3 bits (142), Expect = 3e-09
 Identities = 52/143 (36%), Positives = 66/143 (46%), Gaps = 18/143 (12%)

Query: 27  PVRGPPSPRPAGP-TPRGHGRPAAAVAQPLEPGPGPPERA-----GGGGAARWVRLNVGG 80
           P +  P+  PAGP  PRG G   A      EP PG P  A     GGGG +  + +NVGG
Sbjct: 43  PAQPGPAASPAGPPAPRGPGDRRA------EPCPGLPAAAMGRHGGGGGDSGKIVINVGG 96

Query: 81  TYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKD-ETGA--YLIDRDPTYFGPILNYLRH 137
               T R TL   P +   RL    +PE  +  D + GA  +  DR P  F  +LNY R 
Sbjct: 97  VRHETYRSTLRTLPGT---RLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRT 153

Query: 138 GKLIITKELAEEGVLEEAEFYNI 160
           GKL    ++      EE  F+ I
Sbjct: 154 GKLHCPADVCGPLFEEELGFWGI 176


>gi|13994353 potassium channel tetramerisation domain containing 10
           [Homo sapiens]
          Length = 313

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 46/151 (30%), Positives = 73/151 (48%), Gaps = 16/151 (10%)

Query: 47  PAAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQED 106
           PAAA       G  P        ++++V+LNVGG  + TT QTL ++          + +
Sbjct: 15  PAAATRTTSFKGTSP--------SSKYVKLNVGGALYYTTMQTLTKQDTMLKAMFSGRME 66

Query: 107 PELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAE-EGVLEEAEFYNIASLVR 165
              DS+    G  LIDR   +FG ILNYLR G + + +   E E +L EA++Y +  LV 
Sbjct: 67  VLTDSE----GWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAKYYLVQGLVE 122

Query: 166 LVKERIRDNENRTSQGPVKHVYRVLQCQEEE 196
             +  +   +N+ +  P   V  +   +EE+
Sbjct: 123 ECQAAL---QNKDTYEPFCKVPVITSSKEEQ 150


>gi|55926200 potassium channel tetramerisation domain containing 16
           [Homo sapiens]
          Length = 428

 Score = 58.2 bits (139), Expect = 7e-09
 Identities = 36/96 (37%), Positives = 53/96 (55%), Gaps = 2/96 (2%)

Query: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCC-QEDPELDSDKDETGAYLIDRDPTYFGPIL 132
           V LNVGG  + T   TL   P S L ++   + D   D  KD  G + IDRD   F  IL
Sbjct: 27  VELNVGGQVYFTRHSTLISIPHSLLWKMFSPKRDTANDLAKDSKGRFFIDRDGFLFRYIL 86

Query: 133 NYLRHGKLIITKELAEEGVLE-EAEFYNIASLVRLV 167
           +YLR  ++++     E+G L+ EAE++ +  LV+L+
Sbjct: 87  DYLRDRQVVLPDHFPEKGRLKREAEYFQLPDLVKLL 122


>gi|189571693 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 4/97 (4%)

Query: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILN 133
           V LNVGG  + T+  TL R P S L  +   + P   + +D  G Y IDRD   F  +LN
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFP---TARDPQGNYFIDRDGPLFRYVLN 70

Query: 134 YLRHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKE 169
           +LR  +L +  +  E  +L +EA+FY I  L++ + +
Sbjct: 71  FLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLND 107


>gi|189571691 potassium channel tetramerisation domain containing 6
           [Homo sapiens]
          Length = 237

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 4/97 (4%)

Query: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILN 133
           V LNVGG  + T+  TL R P S L  +   + P   + +D  G Y IDRD   F  +LN
Sbjct: 14  VTLNVGGHLYTTSLTTLTRYPDSMLGAMFGGDFP---TARDPQGNYFIDRDGPLFRYVLN 70

Query: 134 YLRHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKE 169
           +LR  +L +  +  E  +L +EA+FY I  L++ + +
Sbjct: 71  FLRTSELTLPLDFKEFDLLRKEADFYQIEPLIQCLND 107


>gi|30578412 potassium channel tetramerisation domain containing 13
           [Homo sapiens]
          Length = 329

 Score = 55.1 bits (131), Expect = 6e-08
 Identities = 50/167 (29%), Positives = 80/167 (47%), Gaps = 27/167 (16%)

Query: 33  SPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGR 92
           +P+P+G  P     PAA   +PL P             +++V+LNVGG+   TT +TL  
Sbjct: 18  APKPSGLEPG----PAAYGLKPLTPN------------SKYVKLNVGGSLHYTTLRTLTG 61

Query: 93  EPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILNYLRHGKLII---TKELAEE 149
           +       L       ++   D  G  LIDR   +FG ILNYLR G + +   T+EL E 
Sbjct: 62  QDTM----LKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGE- 116

Query: 150 GVLEEAEFYNIASLVRLVKERIRDNENRTSQGPVKHVYRVLQCQEEE 196
            +L EA +Y +  L+   +  ++  + R +  P+  +  V   +EE+
Sbjct: 117 -LLGEARYYLVQGLIEDCQLALQ--QKRETLSPLCLIPMVTSPREEQ 160


>gi|71143104 potassium channel tetramerisation domain containing 21
           [Homo sapiens]
          Length = 260

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 34/98 (34%), Positives = 52/98 (53%), Gaps = 4/98 (4%)

Query: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILN 133
           + LNVGG  + T+  TL   P S L  +   + P   + +D  G   IDRD   F  ILN
Sbjct: 5   ITLNVGGKLYTTSLATLTSFPDSMLGAMFSGKMP---TKRDSQGNCFIDRDGKVFRYILN 61

Query: 134 YLRHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKER 170
           +LR   L + ++  E G+L  EA+FY +  L+  ++E+
Sbjct: 62  FLRTSHLDLPEDFQEMGLLRREADFYQVQPLIEALQEK 99


>gi|194018443 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 21/172 (12%)

Query: 8   PAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGG 67
           P+ + L   G +G  +GG   R   +  P  P         AA   PL      P +   
Sbjct: 8   PSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPL--------AAQGIPL------PAQLTK 53

Query: 68  GGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP-ELDSDKDETGAYLIDRDPT 126
             A   V ++VGG  + ++  TL + P S + RL    +P  LDS K     Y IDRD  
Sbjct: 54  SNAP--VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGE 108

Query: 127 YFGPILNYLRHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKERIRDNENR 177
            F  +L++LR  KL++  +  +  +L EEA +Y +  +VR ++   ++ E R
Sbjct: 109 IFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQR 160


>gi|194018441 potassium channel tetramerisation domain containing 15
           isoform 2 [Homo sapiens]
          Length = 283

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 21/172 (12%)

Query: 8   PAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGG 67
           P+ + L   G +G  +GG   R   +  P  P         AA   PL      P +   
Sbjct: 8   PSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPL--------AAQGIPL------PAQLTK 53

Query: 68  GGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP-ELDSDKDETGAYLIDRDPT 126
             A   V ++VGG  + ++  TL + P S + RL    +P  LDS K     Y IDRD  
Sbjct: 54  SNAP--VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGE 108

Query: 127 YFGPILNYLRHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKERIRDNENR 177
            F  +L++LR  KL++  +  +  +L EEA +Y +  +VR ++   ++ E R
Sbjct: 109 IFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQR 160


>gi|194018439 potassium channel tetramerisation domain containing 15
           isoform 1 [Homo sapiens]
          Length = 234

 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 50/172 (29%), Positives = 79/172 (45%), Gaps = 21/172 (12%)

Query: 8   PAMAGLGGGGGSGVGDGGGPVRGPPSPRPAGPTPRGHGRPAAAVAQPLEPGPGPPERAGG 67
           P+ + L   G +G  +GG   R   +  P  P         AA   PL      P +   
Sbjct: 8   PSGSSLHTHGSTGTAEGGNMSRLSLTRSPVSPL--------AAQGIPL------PAQLTK 53

Query: 68  GGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDP-ELDSDKDETGAYLIDRDPT 126
             A   V ++VGG  + ++  TL + P S + RL    +P  LDS K     Y IDRD  
Sbjct: 54  SNAP--VHIDVGGHMYTSSLATLTKYPDSRISRLFNGTEPIVLDSLKQH---YFIDRDGE 108

Query: 127 YFGPILNYLRHGKLIITKELAEEGVL-EEAEFYNIASLVRLVKERIRDNENR 177
            F  +L++LR  KL++  +  +  +L EEA +Y +  +VR ++   ++ E R
Sbjct: 109 IFRYVLSFLRTSKLLLPDDFKDFSLLYEEARYYQLQPMVRELERWQQEQEQR 160


>gi|27436981 potassium voltage-gated channel, Shal-related
           subfamily, member 1 [Homo sapiens]
          Length = 647

 Score = 51.2 bits (121), Expect = 9e-07
 Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 9/108 (8%)

Query: 53  QPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSD 112
           QPL P PG     G       + +NV G  F T + TL R P + L       + E   D
Sbjct: 25  QPLPPAPGVKASRGD----EVLVVNVSGRRFETWKNTLDRYPDTLLG----SSEKEFFYD 76

Query: 113 KDETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNI 160
            D +G Y  DRDP  F  +LN+ R G+L   ++   +   EE  FY +
Sbjct: 77  AD-SGEYFFDRDPDMFRHVLNFYRTGRLHCPRQECIQAFDEELAFYGL 123


>gi|23308551 potassium channel tetramerisation domain containing 7
           [Homo sapiens]
          Length = 289

 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 35/99 (35%), Positives = 47/99 (47%), Gaps = 21/99 (21%)

Query: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDS--------DKDETGAYLIDRDP 125
           V LN+GG +F T   TL            C ED  L +          D  G Y IDRD 
Sbjct: 53  VPLNIGGAHFTTRLSTLR-----------CYEDTMLAAMFSGRHYIPTDSEGRYFIDRDG 101

Query: 126 TYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLV 164
           T+FG +LN+LR G L   + +    V +EA++Y I  L+
Sbjct: 102 THFGDVLNFLRSGDLPPRERV--RAVYKEAQYYAIGPLL 138


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 41/130 (31%), Positives = 60/130 (46%), Gaps = 12/130 (9%)

Query: 36  PAGPTPRGHGRPAAAVAQPLEPGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPK 95
           PAG T  G  R  +++       P P E       +R VRLNVGG       +TL R P+
Sbjct: 2   PAGMTKHG-SRSTSSLP------PEPMEIVRSKACSRRVRLNVGGLAHEVLWRTLDRLPR 54

Query: 96  SFLCRL--CCQEDPELDSDKD---ETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEG 150
           + L +L  C   D  L+   D   +   Y  DR P  F  ILN+ R G+L + +E+    
Sbjct: 55  TRLGKLRDCNTHDSLLEVCDDYSLDDNEYFFDRHPGAFTSILNFYRTGRLHMMEEMCALS 114

Query: 151 VLEEAEFYNI 160
             +E +++ I
Sbjct: 115 FSQELDYWGI 124


>gi|9789987 potassium voltage-gated channel, Shal-related subfamily,
           member 2 [Homo sapiens]
          Length = 630

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 21/132 (15%)

Query: 57  PGPGPPERAGGGGAARWVRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKD-- 114
           P P PP +         + LNV GT F T + TL R P + L            S++D  
Sbjct: 26  PMPAPPRQERKRTQDALIVLNVSGTRFQTWQDTLERYPDTLLG----------SSERDFF 75

Query: 115 ---ETGAYLIDRDPTYFGPILNYLRHGKLIITKELAEEGVLEEAEFYNIASLV------R 165
              ET  Y  DRDP  F  ILN+ R GKL   +        EE  F+ +   +       
Sbjct: 76  YHPETQQYFFDRDPDIFRHILNFYRTGKLHYPRHECISAYDEELAFFGLIPEIIGDCCYE 135

Query: 166 LVKERIRDNENR 177
             K+R R+N  R
Sbjct: 136 EYKDRRRENAER 147


>gi|40807368 potassium channel regulator isoform 2 [Homo sapiens]
          Length = 229

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILN 133
           V LNVGG  F T   T+ + P S L R+    D E    K   G   +DRD   F  IL+
Sbjct: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEF---KMVGGQIFVDRDGDLFSFILD 63

Query: 134 YLRHGKLIITKELAEEGVLE-EAEFYNIASLVRLV 167
           +LR  +L++  E ++   L+ EA FY + SLV L+
Sbjct: 64  FLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98


>gi|27734697 potassium channel regulator isoform 1 [Homo sapiens]
          Length = 272

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 36/95 (37%), Positives = 50/95 (52%), Gaps = 4/95 (4%)

Query: 74  VRLNVGGTYFVTTRQTLGREPKSFLCRLCCQEDPELDSDKDETGAYLIDRDPTYFGPILN 133
           V LNVGG  F T   T+ + P S L R+    D E    K   G   +DRD   F  IL+
Sbjct: 7   VTLNVGGKIFTTRFSTIKQFPASRLARMLDGRDQEF---KMVGGQIFVDRDGDLFSFILD 63

Query: 134 YLRHGKLIITKELAEEGVLE-EAEFYNIASLVRLV 167
           +LR  +L++  E ++   L+ EA FY + SLV L+
Sbjct: 64  FLRTHQLLLPTEFSDYLRLQREALFYELRSLVDLL 98


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.137    0.411 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,143,593
Number of Sequences: 37866
Number of extensions: 883072
Number of successful extensions: 11944
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 350
Number of HSP's successfully gapped in prelim test: 663
Number of HSP's that attempted gapping in prelim test: 7407
Number of HSP's gapped (non-prelim): 3961
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.