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Search of human proteins with 53759148
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53759148 retinoblastoma binding protein 5 [Homo sapiens] 1093 0.0
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 75 2e-13
gi|23199987 WD repeat domain 5B [Homo sapiens] 68 2e-11
gi|16554629 WD repeat domain 5 [Homo sapiens] 67 3e-11
gi|16554627 WD repeat domain 5 [Homo sapiens] 67 3e-11
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 66 9e-11
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 65 1e-10
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 65 1e-10
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 65 1e-10
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 65 1e-10
gi|19913367 transducin beta-like 1Y [Homo sapiens] 65 2e-10
gi|19913365 transducin beta-like 1Y [Homo sapiens] 65 2e-10
gi|15150805 transducin beta-like 1Y [Homo sapiens] 65 2e-10
gi|199559532 Abelson helper integration site 1 isoform b [Homo s... 63 6e-10
gi|199559490 Abelson helper integration site 1 isoform a [Homo s... 63 6e-10
gi|199559438 Abelson helper integration site 1 isoform a [Homo s... 63 6e-10
gi|31542701 Abelson helper integration site 1 isoform a [Homo sa... 63 6e-10
gi|45238858 WD repeat domain 44 protein [Homo sapiens] 62 2e-09
gi|21071067 TBP-associated factor 5 [Homo sapiens] 57 6e-08
gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo ... 56 9e-08
gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens] 55 2e-07
gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo ... 55 2e-07
gi|32189425 WD repeat domain 69 [Homo sapiens] 53 6e-07
gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens] 53 8e-07
gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens] 53 8e-07
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 50 5e-06
gi|32483361 apoptotic peptidase activating factor 1 isoform d [H... 49 2e-05
gi|4502123 apoptotic peptidase activating factor 1 isoform b [Ho... 49 2e-05
gi|21541824 transducin-like enhancer protein 1 [Homo sapiens] 49 2e-05
gi|34915994 transducin-like enhancer protein 4 [Homo sapiens] 48 2e-05
>gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]
Length = 538
Score = 1093 bits (2828), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK 60
MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK
Sbjct: 1 MNLELLESFGQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAK 60
Query: 61 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ 120
IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ
Sbjct: 61 IISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQ 120
Query: 121 NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT 180
NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT
Sbjct: 121 NKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT 180
Query: 181 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE 240
DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE
Sbjct: 181 DSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE 240
Query: 241 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD 300
PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD
Sbjct: 241 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD 300
Query: 301 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS 360
VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS
Sbjct: 301 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPDFKELDENVEYEERESEFDIEDEDKS 360
Query: 361 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP 420
EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP
Sbjct: 361 EPEQTGADAAEDEEVDVTSVDPIAAFCSSDEELEDSKALLYLPIAPEVEDPEENPYGPPP 420
Query: 421 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK 480
DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK
Sbjct: 421 DAVQTSLMDEGASSEKKRQSSADGSQPPKKKPKTTNIELQGVPNDEVHPLLGVKGDGKSK 480
Query: 481 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL 538
KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL
Sbjct: 481 KKQAGRPKGSKGKEKDSPFKPKLYKGDRGLPLEGSAKGKVQAELSQPLTAGGAISELL 538
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 74.7 bits (182), Expect = 2e-13
Identities = 74/292 (25%), Positives = 123/292 (42%), Gaps = 22/292 (7%)
Query: 30 CTFNRWGTLLAVGCNDGRIVIWD-FLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDN 88
C F+ G+ LA D I++W+ + + H V L ++ DG L SASTD
Sbjct: 72 CKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTDGSMLFSASTDK 131
Query: 89 IVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVD 148
V+ WD +G+ +R + + + Y P + LVC + K +
Sbjct: 132 TVAVWDSETGERVKRLKGHTSFVNSCY-PARRGPQLVCTGSDDGTVKLWDIRKKAAIQTF 190
Query: 149 DDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFAR 208
++ + +F+ + I +G I V L + R + ++ + +
Sbjct: 191 QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR-----GHADSVTGLSLSS 245
Query: 209 KGSCFLINTADRIIRVYDGREILTCGR-----DGEPEPMQKLQDLVNRTPWKKCCFSGDG 263
+GS L N D +RV+D R R G +K +L+ +C +S DG
Sbjct: 246 EGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEK--NLL------RCSWSPDG 297
Query: 264 EYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISS 315
I AGSA +Y+W+ + ++ L G G + +VA+HP PII S SS
Sbjct: 298 SKIAAGSA-DRFVYVWDTTSRRILYKLPGHAGS-INEVAFHPDEPIIISASS 347
Score = 38.9 bits (89), Expect = 0.012
Identities = 22/68 (32%), Positives = 29/68 (42%)
Query: 28 LTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTD 87
L TFN + G D I +WD + + H V L S +G L+S + D
Sbjct: 197 LAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMD 256
Query: 88 NIVSQWDV 95
N V WDV
Sbjct: 257 NTVRVWDV 264
Score = 32.3 bits (72), Expect = 1.1
Identities = 16/60 (26%), Positives = 31/60 (51%)
Query: 28 LTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTD 87
L C+++ G+ +A G D + +WD +R I + H + + + D ++SAS+D
Sbjct: 289 LRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 67.8 bits (164), Expect = 2e-11
Identities = 78/332 (23%), Positives = 127/332 (38%), Gaps = 49/332 (14%)
Query: 14 PEEADGTLDCISMALT-----CTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHP 68
PE + L C + T F+ G LA D I+IW K + H
Sbjct: 26 PENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLE 85
Query: 69 VCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSP-ILKVQYHPRD-------- 119
+ + WS D +LVSAS D + WDV SG C + + S + ++P
Sbjct: 86 ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSF 145
Query: 120 QNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLK 179
V + +K+ + TLS V V + +++ S G A G+ L
Sbjct: 146 DETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTL 205
Query: 180 TDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEP 239
D + SF ++F+ G L T D ++++D + GR
Sbjct: 206 VDDDNPPVSF--------------VKFSPNGKYILTATLDNTLKLWD----YSRGR---- 243
Query: 240 EPMQKLQDLVNRTPWKKCCFSG----DGEYIVAGSARQHALYIWEKSIGNLVKILHGTRG 295
L+ K C F+ G++IV+GS + +YIW +V+ L G
Sbjct: 244 ----CLKTYTGHKNEKYCIFANFSVTGGKWIVSGS-EDNLVYIWNLQTKEIVQKLQG-HT 297
Query: 296 ELLLDVAWHPVRPIIASI---SSGVVSIWAQN 324
++++ A HP +IAS + + +W N
Sbjct: 298 DVVISAACHPTENLIASAALENDKTIKLWMSN 329
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/286 (24%), Positives = 116/286 (40%), Gaps = 25/286 (8%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
F+ G LA D I IW K IS H + + WS D + LVSAS D +
Sbjct: 53 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLK 112
Query: 92 QWDVLSGDCDQRFRFPSP-ILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDD 150
WDV SG C + + S + ++P Q+ ++V V + + + +
Sbjct: 113 IWDVSSGKCLKTLKGHSNYVFCCNFNP--QSNLIVSGSFDESVRIWDVKTGKCLKTLPAH 170
Query: 151 SDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKG 210
SD F+R G I + + G + T S + T + + ++F+ G
Sbjct: 171 SDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLK----TLIDDDNPPVSFVKFSPNG 226
Query: 211 SCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSG----DGEYI 266
L T D ++++D + + L+ K C F+ G++I
Sbjct: 227 KYILAATLDNTLKLWDYSK------------GKCLKTYTGHKNEKYCIFANFSVTGGKWI 274
Query: 267 VAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIAS 312
V+GS + +YIW +V+ L G ++++ A HP IIAS
Sbjct: 275 VSGS-EDNLVYIWNLQTKEIVQKLQG-HTDVVISTACHPTENIIAS 318
Score = 55.8 bits (133), Expect = 9e-08
Identities = 27/71 (38%), Positives = 37/71 (52%)
Query: 30 CTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNI 89
C FN L+ G D + IWD T K + AH PV ++ ++RDG +VS+S D +
Sbjct: 135 CNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGL 194
Query: 90 VSQWDVLSGDC 100
WD SG C
Sbjct: 195 CRIWDTASGQC 205
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 67.4 bits (163), Expect = 3e-11
Identities = 70/286 (24%), Positives = 116/286 (40%), Gaps = 25/286 (8%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
F+ G LA D I IW K IS H + + WS D + LVSAS D +
Sbjct: 53 FSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASDDKTLK 112
Query: 92 QWDVLSGDCDQRFRFPSP-ILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDD 150
WDV SG C + + S + ++P Q+ ++V V + + + +
Sbjct: 113 IWDVSSGKCLKTLKGHSNYVFCCNFNP--QSNLIVSGSFDESVRIWDVKTGKCLKTLPAH 170
Query: 151 SDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKG 210
SD F+R G I + + G + T S + T + + ++F+ G
Sbjct: 171 SDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLK----TLIDDDNPPVSFVKFSPNG 226
Query: 211 SCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSG----DGEYI 266
L T D ++++D + + L+ K C F+ G++I
Sbjct: 227 KYILAATLDNTLKLWDYSK------------GKCLKTYTGHKNEKYCIFANFSVTGGKWI 274
Query: 267 VAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIAS 312
V+GS + +YIW +V+ L G ++++ A HP IIAS
Sbjct: 275 VSGS-EDNLVYIWNLQTKEIVQKLQG-HTDVVISTACHPTENIIAS 318
Score = 55.8 bits (133), Expect = 9e-08
Identities = 27/71 (38%), Positives = 37/71 (52%)
Query: 30 CTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNI 89
C FN L+ G D + IWD T K + AH PV ++ ++RDG +VS+S D +
Sbjct: 135 CNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGL 194
Query: 90 VSQWDVLSGDC 100
WD SG C
Sbjct: 195 CRIWDTASGQC 205
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 65.9 bits (159), Expect = 9e-11
Identities = 82/326 (25%), Positives = 129/326 (39%), Gaps = 50/326 (15%)
Query: 10 GQNYPEEADGTLDCISMALTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPV 69
GQ+ P D T + +N GTLLA G DG IW +A + H P+
Sbjct: 219 GQDVPSNKDVT--------SLDWNSEGTLLATGSYDGFARIWT-KDGNLASTLGQHKGPI 269
Query: 70 CSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPS-PILKVQYHPRDQNKVLVCPM 128
+L W++ G+ ++SA D WD +G+ Q+F F S P L V + + N C
Sbjct: 270 FALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDW--QSNNTFASCST 327
Query: 129 KSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYI--YTGNAKGKILVLKTDS--QD 184
+ L + + +++N + +D G + + + KI +K D+ D
Sbjct: 328 DMCIHVCKLGQDRPIKTFQGHTNEVNAI-KWDPTGNLLASCSDDMTLKIWSMKQDNCVHD 386
Query: 185 LVASFR---------VTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGR 235
L A + GT+N A + A S + DR I ++
Sbjct: 387 LQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIH---------- 436
Query: 236 DGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRG 295
+ K Q+ P FS DG Y+ +GS ++IW G LV GT G
Sbjct: 437 -----TLTKHQE-----PVYSVAFSPDGRYLASGSF-DKCVHIWNTQTGALVHSYRGTGG 485
Query: 296 ELLLDVAWHPVRPII-ASISSGVVSI 320
+ +V W+ + AS S G V +
Sbjct: 486 --IFEVCWNAAGDKVGASASDGSVCV 509
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 65.5 bits (158), Expect = 1e-10
Identities = 76/300 (25%), Positives = 123/300 (41%), Gaps = 34/300 (11%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
+N GTLLA G DG IW +A + H P+ +L W+R G+ ++SA D
Sbjct: 245 WNTNGTLLATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTI 303
Query: 92 QWDVLSGDCDQRFRFPS-PILKVQYHPR-------DQNKVLVCPMK-SAPVMLTLSDSKH 142
WD +G+ Q+F F S P L V + + VC + PV +
Sbjct: 304 IWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNE 363
Query: 143 VVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIK 202
V D S + + + D I++ + I L+ ++++ TG + +
Sbjct: 364 VNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNS 423
Query: 203 SIEFARKGSCFLINTADRIIRVYD-GREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSG 261
+I A + D +R++D R + T EP+ + FS
Sbjct: 424 NIMLASA-------SFDSTVRLWDIERGVCTHTLTKHQEPVYSV------------AFSP 464
Query: 262 DGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPII-ASISSGVVSI 320
DG+Y+ +GS ++IW GNLV GT G + +V W+ + AS S G V +
Sbjct: 465 DGKYLASGSF-DKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCV 521
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 65.5 bits (158), Expect = 1e-10
Identities = 76/300 (25%), Positives = 123/300 (41%), Gaps = 34/300 (11%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
+N GTLLA G DG IW +A + H P+ +L W+R G+ ++SA D
Sbjct: 245 WNTNGTLLATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTI 303
Query: 92 QWDVLSGDCDQRFRFPS-PILKVQYHPR-------DQNKVLVCPMK-SAPVMLTLSDSKH 142
WD +G+ Q+F F S P L V + + VC + PV +
Sbjct: 304 IWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNE 363
Query: 143 VVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIK 202
V D S + + + D I++ + I L+ ++++ TG + +
Sbjct: 364 VNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNS 423
Query: 203 SIEFARKGSCFLINTADRIIRVYD-GREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSG 261
+I A + D +R++D R + T EP+ + FS
Sbjct: 424 NIMLASA-------SFDSTVRLWDIERGVCTHTLTKHQEPVYSV------------AFSP 464
Query: 262 DGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPII-ASISSGVVSI 320
DG+Y+ +GS ++IW GNLV GT G + +V W+ + AS S G V +
Sbjct: 465 DGKYLASGSF-DKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCV 521
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 65.5 bits (158), Expect = 1e-10
Identities = 76/300 (25%), Positives = 123/300 (41%), Gaps = 34/300 (11%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
+N GTLLA G DG IW +A + H P+ +L W+R G+ ++SA D
Sbjct: 296 WNTNGTLLATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTI 354
Query: 92 QWDVLSGDCDQRFRFPS-PILKVQYHPR-------DQNKVLVCPMK-SAPVMLTLSDSKH 142
WD +G+ Q+F F S P L V + + VC + PV +
Sbjct: 355 IWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNE 414
Query: 143 VVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIK 202
V D S + + + D I++ + I L+ ++++ TG + +
Sbjct: 415 VNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNS 474
Query: 203 SIEFARKGSCFLINTADRIIRVYD-GREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSG 261
+I A + D +R++D R + T EP+ + FS
Sbjct: 475 NIMLASA-------SFDSTVRLWDIERGVCTHTLTKHQEPVYSV------------AFSP 515
Query: 262 DGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPII-ASISSGVVSI 320
DG+Y+ +GS ++IW GNLV GT G + +V W+ + AS S G V +
Sbjct: 516 DGKYLASGSF-DKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCV 572
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 65.5 bits (158), Expect = 1e-10
Identities = 76/300 (25%), Positives = 123/300 (41%), Gaps = 34/300 (11%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
+N GTLLA G DG IW +A + H P+ +L W+R G+ ++SA D
Sbjct: 296 WNTNGTLLATGSYDGFARIWTE-DGNLASTLGQHKGPIFALKWNRKGNYILSAGVDKTTI 354
Query: 92 QWDVLSGDCDQRFRFPS-PILKVQYHPR-------DQNKVLVCPMK-SAPVMLTLSDSKH 142
WD +G+ Q+F F S P L V + + VC + PV +
Sbjct: 355 IWDAHTGEAKQQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKTFQGHTNE 414
Query: 143 VVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIK 202
V D S + + + D I++ + I L+ ++++ TG + +
Sbjct: 415 VNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNS 474
Query: 203 SIEFARKGSCFLINTADRIIRVYD-GREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSG 261
+I A + D +R++D R + T EP+ + FS
Sbjct: 475 NIMLASA-------SFDSTVRLWDIERGVCTHTLTKHQEPVYSV------------AFSP 515
Query: 262 DGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPII-ASISSGVVSI 320
DG+Y+ +GS ++IW GNLV GT G + +V W+ + AS S G V +
Sbjct: 516 DGKYLASGSF-DKCVHIWNTQSGNLVHSYRGTGG--IFEVCWNARGDKVGASASDGSVCV 572
>gi|19913367 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 64.7 bits (156), Expect = 2e-10
Identities = 73/299 (24%), Positives = 126/299 (42%), Gaps = 32/299 (10%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
+N GTLLA+G DG IW +A + H P+ +L W++ G+ ++SA D
Sbjct: 243 WNSDGTLLAMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTI 301
Query: 92 QWDVLSGDCDQRFRFPS-PILKVQYHPR-------DQNKVLVCPMKSAPVMLTLSDSKHV 143
WD +G+ Q+F F S P L V + + VC + + T +
Sbjct: 302 IWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNE 361
Query: 144 VLPVD-DDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIK 202
V + D S + + + D I++ + L+ S+++ TG + +
Sbjct: 362 VNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNS 421
Query: 203 SIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGD 262
SI A + D +R++D + + + K Q+ P FS D
Sbjct: 422 SIMLASA-------SFDSTVRLWDVEQGVC------THTLMKHQE-----PVYSVAFSPD 463
Query: 263 GEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPII-ASISSGVVSI 320
G+Y+ +GS ++ ++IW G+LV GT G + +V W+ + AS S G V +
Sbjct: 464 GKYLASGSFDKY-VHIWNTQSGSLVHSYQGTGG--IFEVCWNARGDKVGASASDGSVCV 519
>gi|19913365 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 64.7 bits (156), Expect = 2e-10
Identities = 73/299 (24%), Positives = 126/299 (42%), Gaps = 32/299 (10%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
+N GTLLA+G DG IW +A + H P+ +L W++ G+ ++SA D
Sbjct: 243 WNSDGTLLAMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTI 301
Query: 92 QWDVLSGDCDQRFRFPS-PILKVQYHPR-------DQNKVLVCPMKSAPVMLTLSDSKHV 143
WD +G+ Q+F F S P L V + + VC + + T +
Sbjct: 302 IWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNE 361
Query: 144 VLPVD-DDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIK 202
V + D S + + + D I++ + L+ S+++ TG + +
Sbjct: 362 VNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNS 421
Query: 203 SIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGD 262
SI A + D +R++D + + + K Q+ P FS D
Sbjct: 422 SIMLASA-------SFDSTVRLWDVEQGVC------THTLMKHQE-----PVYSVAFSPD 463
Query: 263 GEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPII-ASISSGVVSI 320
G+Y+ +GS ++ ++IW G+LV GT G + +V W+ + AS S G V +
Sbjct: 464 GKYLASGSFDKY-VHIWNTQSGSLVHSYQGTGG--IFEVCWNARGDKVGASASDGSVCV 519
>gi|15150805 transducin beta-like 1Y [Homo sapiens]
Length = 522
Score = 64.7 bits (156), Expect = 2e-10
Identities = 73/299 (24%), Positives = 126/299 (42%), Gaps = 32/299 (10%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
+N GTLLA+G DG IW +A + H P+ +L W++ G+ ++SA D
Sbjct: 243 WNSDGTLLAMGSYDGFARIWTE-NGNLASTLGQHKGPIFALKWNKKGNYVLSAGVDKTTI 301
Query: 92 QWDVLSGDCDQRFRFPS-PILKVQYHPR-------DQNKVLVCPMKSAPVMLTLSDSKHV 143
WD +G+ Q+F F S P L V + + VC + + T +
Sbjct: 302 IWDAHTGEAKQQFPFHSAPALDVDWQNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNE 361
Query: 144 VLPVD-DDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIK 202
V + D S + + + D I++ + L+ S+++ TG + +
Sbjct: 362 VNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNS 421
Query: 203 SIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGD 262
SI A + D +R++D + + + K Q+ P FS D
Sbjct: 422 SIMLASA-------SFDSTVRLWDVEQGVC------THTLMKHQE-----PVYSVAFSPD 463
Query: 263 GEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPII-ASISSGVVSI 320
G+Y+ +GS ++ ++IW G+LV GT G + +V W+ + AS S G V +
Sbjct: 464 GKYLASGSFDKY-VHIWNTQSGSLVHSYQGTGG--IFEVCWNARGDKVGASASDGSVCV 519
>gi|199559532 Abelson helper integration site 1 isoform b [Homo
sapiens]
Length = 1053
Score = 63.2 bits (152), Expect = 6e-10
Identities = 66/303 (21%), Positives = 126/303 (41%), Gaps = 29/303 (9%)
Query: 32 FNRWGTLLAVGC--NDGR-IVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDN 88
F+ G +LA C DG I++++ + + + H++ + L WS+D H ++++S+D
Sbjct: 617 FSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDG 676
Query: 89 IVSQW--DVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTL---SDSKHV 143
W ++ + + + PS + ++HP + V+ S + + DS +
Sbjct: 677 TARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAIL 736
Query: 144 VLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT-----DSQDLVASFRVTTGTSNT 198
V D FD G ++Y+G+ G I+V T D + V + + T
Sbjct: 737 VRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKET 796
Query: 199 ----TAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPW 254
I +E G LI+T D +R+ D R ++ G +K+ + TP
Sbjct: 797 EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTL--TPC 854
Query: 255 KKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGEL-LLDVAWHPVRPIIASI 313
F+G + IV Y+W G V + + + D+++HP ++A
Sbjct: 855 GTFLFAGSEDGIV---------YVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFC 905
Query: 314 SSG 316
+ G
Sbjct: 906 AFG 908
Score = 32.7 bits (73), Expect = 0.86
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 14/113 (12%)
Query: 36 GTLLAVGCNDGRIVIWDFLTRGIAKIISA-----HIHPVCSLCWSRDGHKLVSASTDNIV 90
G L + D + I D K + A IH + C G L + S D IV
Sbjct: 812 GKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPC----GTFLFAGSEDGIV 867
Query: 91 SQWDVLSGDCDQRFR---FPSPILKVQYHPRDQNKVLVCPM-KSAPVMLTLSD 139
W+ +G+ + F SPI + YHP +N V C ++ P++L + D
Sbjct: 868 YVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCAFGQNEPILLYIYD 919
>gi|199559490 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 63.2 bits (152), Expect = 6e-10
Identities = 66/303 (21%), Positives = 126/303 (41%), Gaps = 29/303 (9%)
Query: 32 FNRWGTLLAVGC--NDGR-IVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDN 88
F+ G +LA C DG I++++ + + + H++ + L WS+D H ++++S+D
Sbjct: 617 FSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDG 676
Query: 89 IVSQW--DVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTL---SDSKHV 143
W ++ + + + PS + ++HP + V+ S + + DS +
Sbjct: 677 TARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAIL 736
Query: 144 VLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT-----DSQDLVASFRVTTGTSNT 198
V D FD G ++Y+G+ G I+V T D + V + + T
Sbjct: 737 VRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKET 796
Query: 199 ----TAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPW 254
I +E G LI+T D +R+ D R ++ G +K+ + TP
Sbjct: 797 EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTL--TPC 854
Query: 255 KKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGEL-LLDVAWHPVRPIIASI 313
F+G + IV Y+W G V + + + D+++HP ++A
Sbjct: 855 GTFLFAGSEDGIV---------YVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFC 905
Query: 314 SSG 316
+ G
Sbjct: 906 AFG 908
Score = 32.7 bits (73), Expect = 0.86
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 14/113 (12%)
Query: 36 GTLLAVGCNDGRIVIWDFLTRGIAKIISA-----HIHPVCSLCWSRDGHKLVSASTDNIV 90
G L + D + I D K + A IH + C G L + S D IV
Sbjct: 812 GKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPC----GTFLFAGSEDGIV 867
Query: 91 SQWDVLSGDCDQRFR---FPSPILKVQYHPRDQNKVLVCPM-KSAPVMLTLSD 139
W+ +G+ + F SPI + YHP +N V C ++ P++L + D
Sbjct: 868 YVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCAFGQNEPILLYIYD 919
>gi|199559438 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 63.2 bits (152), Expect = 6e-10
Identities = 66/303 (21%), Positives = 126/303 (41%), Gaps = 29/303 (9%)
Query: 32 FNRWGTLLAVGC--NDGR-IVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDN 88
F+ G +LA C DG I++++ + + + H++ + L WS+D H ++++S+D
Sbjct: 617 FSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDG 676
Query: 89 IVSQW--DVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTL---SDSKHV 143
W ++ + + + PS + ++HP + V+ S + + DS +
Sbjct: 677 TARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAIL 736
Query: 144 VLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT-----DSQDLVASFRVTTGTSNT 198
V D FD G ++Y+G+ G I+V T D + V + + T
Sbjct: 737 VRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKET 796
Query: 199 ----TAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPW 254
I +E G LI+T D +R+ D R ++ G +K+ + TP
Sbjct: 797 EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTL--TPC 854
Query: 255 KKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGEL-LLDVAWHPVRPIIASI 313
F+G + IV Y+W G V + + + D+++HP ++A
Sbjct: 855 GTFLFAGSEDGIV---------YVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFC 905
Query: 314 SSG 316
+ G
Sbjct: 906 AFG 908
Score = 32.7 bits (73), Expect = 0.86
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 14/113 (12%)
Query: 36 GTLLAVGCNDGRIVIWDFLTRGIAKIISA-----HIHPVCSLCWSRDGHKLVSASTDNIV 90
G L + D + I D K + A IH + C G L + S D IV
Sbjct: 812 GKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPC----GTFLFAGSEDGIV 867
Query: 91 SQWDVLSGDCDQRFR---FPSPILKVQYHPRDQNKVLVCPM-KSAPVMLTLSD 139
W+ +G+ + F SPI + YHP +N V C ++ P++L + D
Sbjct: 868 YVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCAFGQNEPILLYIYD 919
>gi|31542701 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 63.2 bits (152), Expect = 6e-10
Identities = 66/303 (21%), Positives = 126/303 (41%), Gaps = 29/303 (9%)
Query: 32 FNRWGTLLAVGC--NDGR-IVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDN 88
F+ G +LA C DG I++++ + + + H++ + L WS+D H ++++S+D
Sbjct: 617 FSHNGRILAAACASRDGYPIILYEIPSGRFMRELCGHLNIIYDLSWSKDDHYILTSSSDG 676
Query: 89 IVSQW--DVLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTL---SDSKHV 143
W ++ + + + PS + ++HP + V+ S + + DS +
Sbjct: 677 TARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRELVVTGCYDSMIRIWKVEMREDSAIL 736
Query: 144 VLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKT-----DSQDLVASFRVTTGTSNT 198
V D FD G ++Y+G+ G I+V T D + V + + T
Sbjct: 737 VRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVWNTYVKINDLEHSVHHWTINKEIKET 796
Query: 199 ----TAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPW 254
I +E G LI+T D +R+ D R ++ G +K+ + TP
Sbjct: 797 EFKGIPISYLEIHPNGKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTL--TPC 854
Query: 255 KKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGEL-LLDVAWHPVRPIIASI 313
F+G + IV Y+W G V + + + D+++HP ++A
Sbjct: 855 GTFLFAGSEDGIV---------YVWNPETGEQVAMYSDLPFKSPIRDISYHPFENMVAFC 905
Query: 314 SSG 316
+ G
Sbjct: 906 AFG 908
Score = 32.7 bits (73), Expect = 0.86
Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 14/113 (12%)
Query: 36 GTLLAVGCNDGRIVIWDFLTRGIAKIISA-----HIHPVCSLCWSRDGHKLVSASTDNIV 90
G L + D + I D K + A IH + C G L + S D IV
Sbjct: 812 GKRLLIHTKDSTLRIMDLRILVARKFVGAANYREKIHSTLTPC----GTFLFAGSEDGIV 867
Query: 91 SQWDVLSGDCDQRFR---FPSPILKVQYHPRDQNKVLVCPM-KSAPVMLTLSD 139
W+ +G+ + F SPI + YHP +N V C ++ P++L + D
Sbjct: 868 YVWNPETGEQVAMYSDLPFKSPIRDISYHP-FENMVAFCAFGQNEPILLYIYD 919
>gi|45238858 WD repeat domain 44 protein [Homo sapiens]
Length = 913
Score = 61.6 bits (148), Expect = 2e-09
Identities = 75/316 (23%), Positives = 127/316 (40%), Gaps = 34/316 (10%)
Query: 65 HIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVL 124
H + L WS++ + L+S+S D V W + +C F+ + + +HPRD L
Sbjct: 606 HTADLLDLSWSKN-YFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFL 664
Query: 125 VCPMKSAPVMLTLSDSKHVVL-PVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQ 183
+ + + D K + VD + L A+F + G+Y G G+ + T+
Sbjct: 665 SGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHL 724
Query: 184 DLVASFRV--TTGTSNT-TAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE 240
V T G + I IE + L+ + D IR+YD R++
Sbjct: 725 KYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDL---------S 775
Query: 241 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD 300
K + VN + K FS D Y+V+GS ++ +YIW + +L K R +
Sbjct: 776 LSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKY-VYIW-STYHDLSKFTSVRRDR---N 830
Query: 301 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPD-FKELDENVEYEERESEFDIEDEDK 359
W ++ A N V + FAP+ L +V+ E+ E ED +
Sbjct: 831 DFWEGIK--------------AHNAVVTSAIFAPNPSLMLSLDVQSEKSEGNEKSEDAEV 876
Query: 360 SEPEQTGADAAEDEEV 375
+ +G ++ EV
Sbjct: 877 LDATPSGIMKTDNTEV 892
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 56.6 bits (135), Expect = 6e-08
Identities = 28/66 (42%), Positives = 36/66 (54%)
Query: 31 TFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIV 90
TF+ G LA G DGR+++WD + + H VCSL +SRDG L S S DN V
Sbjct: 676 TFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTV 735
Query: 91 SQWDVL 96
WD +
Sbjct: 736 RLWDAI 741
Score = 42.7 bits (99), Expect = 8e-04
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 28 LTCT-FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSAST 86
+ CT F+ +A G D + +WD L +I + H P+ SL +S +G L + +T
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689
Query: 87 DNIVSQWDVLSG 98
D V WD+ G
Sbjct: 690 DGRVLLWDIGHG 701
Score = 34.3 bits (77), Expect = 0.30
Identities = 50/233 (21%), Positives = 92/233 (39%), Gaps = 22/233 (9%)
Query: 50 IWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPS- 108
I D T KI+ H PV +S D + L+S+S D V W + + C ++ +
Sbjct: 527 IMDEKTASELKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNY 586
Query: 109 PILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRRGEYIYT 168
P+ Q+ P V + A + T + + + +D+N F Y+ T
Sbjct: 587 PVWDTQFSPYGYYFVSGGHDRVARLWAT-DHYQPLRIFAGHLADVN-CTRFHPNSNYVAT 644
Query: 169 GNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYD-G 227
G+A + + + + V F T + I S+ F+ G D + ++D G
Sbjct: 645 GSADRTVRLWDVLNGNCVRIF-----TGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIG 699
Query: 228 REILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWE 280
++ G + + L+ FS DGE + +GS + + +W+
Sbjct: 700 HGLMVGELKGHTDTVCSLR------------FSRDGEILASGS-MDNTVRLWD 739
>gi|109948304 smu-1 suppressor of mec-8 and unc-52 homolog [Homo
sapiens]
Length = 513
Score = 55.8 bits (133), Expect = 9e-08
Identities = 69/303 (22%), Positives = 124/303 (40%), Gaps = 26/303 (8%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHP--------VCSLCWSRDGHKLVS 83
F+ G L G DG I +W+F T I K + V +C+SRD L +
Sbjct: 222 FSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLAT 281
Query: 84 ASTDNIVSQWDVLSGDCDQRF-RFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKH 142
+ D + W + SG C +RF R S + +D +++L + L K
Sbjct: 282 GAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKT 341
Query: 143 VVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNT--TA 200
+ S +N A+F + G YI + ++ G + + + + +F+ T+ T T
Sbjct: 342 LKEFRGHSSFVN-EATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITV 400
Query: 201 IKSIEFARKGSCFLI-NTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCF 259
I + F++ N ++ ++ + +I+ G+ E D V C
Sbjct: 401 NSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREG----GDFV------CCAL 450
Query: 260 SGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASIS-SGVV 318
S GE+I LY + G L + L + ++ +A HP + +IA+ S G++
Sbjct: 451 SPRGEWIYC-VGEDFVLYCFSTVTGKLERTL-TVHEKDVIGIAHHPHQNLIATYSEDGLL 508
Query: 319 SIW 321
+W
Sbjct: 509 KLW 511
Score = 40.4 bits (93), Expect = 0.004
Identities = 39/172 (22%), Positives = 71/172 (41%), Gaps = 14/172 (8%)
Query: 28 LTCTFNRWGTLLAVGCNDGRIVIWDFLT-RGIAKIISAHIHPVCSLCWSRDGHKLVSAST 86
L F+R +LA G DG+I +W + + + + AH V L +S+D +++SAS
Sbjct: 268 LCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASF 327
Query: 87 DNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVL---------VCPMKSAPVMLTL 137
D + + SG + FR S + +D + ++ + MK+ T
Sbjct: 328 DQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTF 387
Query: 138 SDSKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASF 189
K + D +N V + E+ N ++++ Q +V SF
Sbjct: 388 ---KSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQ-IVRSF 435
Score = 35.0 bits (79), Expect = 0.17
Identities = 33/153 (21%), Positives = 63/153 (41%), Gaps = 11/153 (7%)
Query: 25 SMALTC-TFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVS 83
S +TC +F++ + + D I I + K H V +++DGH ++S
Sbjct: 307 SKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIIS 366
Query: 84 ASTDNIVSQWDVLSGDCDQRFR-------FPSPILKVQYHPRDQNKVLVCPMKSAPVMLT 136
AS+D V W++ + +C F+ + V P++ +VC + V++
Sbjct: 367 ASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMN 426
Query: 137 LSDS--KHVVLPVDDDSDLNVVASFDRRGEYIY 167
+ + + D V + RGE+IY
Sbjct: 427 MQGQIVRSFSSGKREGGDF-VCCALSPRGEWIY 458
>gi|48762926 PWP2 periodic tryptophan protein homolog [Homo sapiens]
Length = 919
Score = 55.1 bits (131), Expect = 2e-07
Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 19/191 (9%)
Query: 140 SKHVVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTT 199
S+ VL + V ++ G+YI TG GK+ V T ++ F T T +++
Sbjct: 362 SESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNT-----LSGFCFVTFTEHSS 416
Query: 200 AIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRTPWKKCCF 259
+ + F G + ++ D +R +D P P Q +
Sbjct: 417 GVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQ----------FSCVAV 466
Query: 260 SGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASIS-SGVV 318
GE + AG+ +++W G L+ +L G G + + ++P++ ++AS S V
Sbjct: 467 DASGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGP-ISGLCFNPMKSVLASASWDKTV 525
Query: 319 SIWAQNQVENW 329
+W + ++W
Sbjct: 526 RLW--DMFDSW 534
Score = 43.1 bits (100), Expect = 6e-04
Identities = 20/69 (28%), Positives = 36/69 (52%), Gaps = 1/69 (1%)
Query: 33 NRWGTLLAVGCND-GRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
N G +A GC+ G++++W++ + H + + +L +S DG +V+ D V
Sbjct: 339 NSSGDWIAFGCSGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVK 398
Query: 92 QWDVLSGDC 100
W+ LSG C
Sbjct: 399 VWNTLSGFC 407
Score = 40.4 bits (93), Expect = 0.004
Identities = 30/111 (27%), Positives = 49/111 (44%), Gaps = 6/111 (5%)
Query: 36 GTLLAVGCNDG-RIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWD 94
G +++ G D I +W T + ++S H P+ LC++ L SAS D V WD
Sbjct: 470 GEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNPMKSVLASASWDKTVRLWD 529
Query: 95 VL-SGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVV 144
+ S + S L V + P D ++ V + S +T D ++ V
Sbjct: 530 MFDSWRTKETLALTSDALAVTFRP-DGAELAVATLNS---QITFWDPENAV 576
Score = 31.6 bits (70), Expect = 1.9
Identities = 17/74 (22%), Positives = 35/74 (47%)
Query: 36 GTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDV 95
G + G +DG++ +W+ L+ + H V + ++ G+ +V++S D V +D+
Sbjct: 385 GQYIVTGGDDGKVKVWNTLSGFCFVTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDL 444
Query: 96 LSGDCDQRFRFPSP 109
+ F P P
Sbjct: 445 HRYRNFRTFTSPRP 458
>gi|18677720 WD repeat and SOCS box-containing 1 isoform 1 [Homo
sapiens]
Length = 421
Score = 54.7 bits (130), Expect = 2e-07
Identities = 66/285 (23%), Positives = 122/285 (42%), Gaps = 33/285 (11%)
Query: 8 SFGQNYPEEADGTLDCISMAL-TCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHI 66
+FG + PE+ C+++ F + LLA G N+GRI IWD T + + H
Sbjct: 114 AFGSSVPEKQSR---CVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHT 170
Query: 67 HPVCSLCWSRDGHK-LVSASTDNIVSQWDVL-SGDCDQRFR-FPSPILKVQYHPRDQNKV 123
V L ++ DG LVSAS D + WD+ G+ + R + + + P +
Sbjct: 171 EVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSP---DSS 227
Query: 124 LVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVA-SFDRRGEYIYTGNAKGKILVLKTDS 182
++C + ++ + + K+ ++ + +VVA F G + T + ++ + +
Sbjct: 228 MLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHN 287
Query: 183 QDLVASF--------RVTTGTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREILTCG 234
D++ F + G +N ++S+ F+ G D+++R +
Sbjct: 288 GDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHDGLHVASLADDKMVRFW--------- 338
Query: 235 RDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIW 279
R E P+Q + L N C FS DG + AG+ ++Y W
Sbjct: 339 RIDEDYPVQ-VAPLSNGL---CCAFSTDGSVLAAGT-HDGSVYFW 378
Score = 33.1 bits (74), Expect = 0.66
Identities = 19/65 (29%), Positives = 36/65 (55%), Gaps = 3/65 (4%)
Query: 259 FSGDGEYIVAGSARQHALYIWE-KSIGNLVKILHGTRGELLLDVAWHPVRPIIASI-SSG 316
F+ DG I+ ++R L +W+ K GN++K+L G + + A+ P ++ S+ +S
Sbjct: 178 FAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQ-NWVYSCAFSPDSSMLCSVGASK 236
Query: 317 VVSIW 321
V +W
Sbjct: 237 AVFLW 241
>gi|32189425 WD repeat domain 69 [Homo sapiens]
Length = 415
Score = 53.1 bits (126), Expect = 6e-07
Identities = 57/258 (22%), Positives = 101/258 (39%), Gaps = 36/258 (13%)
Query: 31 TFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIV 90
+FN TL+A G D +WD + H + SL ++ G ++++ S D+ V
Sbjct: 184 SFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGSFDHTV 243
Query: 91 SQWD--------VLSGDCDQRFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKH 142
WD +L G C + I ++ D + +L M + ++ K
Sbjct: 244 VVWDADTGRKVNILIGHC-------AEISSASFN-WDCSLILTGSMDKTCKLWDATNGKC 295
Query: 143 VVLPVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIK 202
V D ++ + + FD G+ I T +A G + ++ +A G I
Sbjct: 296 VATLTGHDDEI-LDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEG-----EIS 349
Query: 203 SIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPEPMQKLQDLVNRT-PWKKCCFSG 261
I F +G+ L ++D+ R++D + Q LQ L T C F+
Sbjct: 350 KISFNPQGNHLLTGSSDKTARIWDA------------QTGQCLQVLEGHTDEIFSCAFNY 397
Query: 262 DGEYIVAGSARQHALYIW 279
G ++ GS + + IW
Sbjct: 398 KGNIVITGS-KDNTCRIW 414
Score = 48.5 bits (114), Expect = 2e-05
Identities = 67/321 (20%), Positives = 124/321 (38%), Gaps = 39/321 (12%)
Query: 33 NRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRD-GHKLVSASTDNIVS 91
N+ G+ G D +WD + + H + V ++ ++ G K+ + S D
Sbjct: 101 NKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGSFDKTCK 160
Query: 92 QWDVLSGDCDQRFR-FPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDD 150
W V +G C FR + I+ + ++P+ V M + + + + + V
Sbjct: 161 LWSVETGKCYHTFRGHTAEIVCLSFNPQ-STLVATGSMDTTAKLWDIQNGEEVYTLRGHS 219
Query: 151 SDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQDLV------------ASFR-----VTT 193
+++ + SF+ G+ I TG+ ++V D+ V ASF + T
Sbjct: 220 AEI-ISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILT 278
Query: 194 GTSNTTAIKSIEFARKGSCFLINTA--DRIIRV---YDGREILTCGRDGEP--------E 240
G+ + T + A G C T D I+ Y G+ I T DG +
Sbjct: 279 GSMDKTC--KLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRK 336
Query: 241 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD 300
+ KL+ + K F+ G +++ GS+ + A IW+ G +++L G E+
Sbjct: 337 CIAKLEG--HEGEISKISFNPQGNHLLTGSSDKTA-RIWDAQTGQCLQVLEGHTDEIFSC 393
Query: 301 VAWHPVRPIIASISSGVVSIW 321
+ +I IW
Sbjct: 394 AFNYKGNIVITGSKDNTCRIW 414
Score = 37.0 bits (84), Expect = 0.046
Identities = 20/75 (26%), Positives = 33/75 (44%)
Query: 28 LTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTD 87
L F+ G L+A DG I+ TR + H + + ++ G+ L++ S+D
Sbjct: 307 LDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSD 366
Query: 88 NIVSQWDVLSGDCDQ 102
WD +G C Q
Sbjct: 367 KTARIWDAQTGQCLQ 381
Score = 30.8 bits (68), Expect = 3.3
Identities = 26/143 (18%), Positives = 56/143 (39%), Gaps = 3/143 (2%)
Query: 29 TCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDN 88
+ +FN +L+ G D +WD ++ H + C+ G + +AS D
Sbjct: 266 SASFNWDCSLILTGSMDKTCKLWDATNGKCVATLTGHDDEILDSCFDYTGKLIATASADG 325
Query: 89 IVSQWDVLSGDCDQRFR-FPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPV 147
+ + C + I K+ ++P+ + + K+A + + VL
Sbjct: 326 TARIFSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVL-- 383
Query: 148 DDDSDLNVVASFDRRGEYIYTGN 170
+ +D +F+ +G + TG+
Sbjct: 384 EGHTDEIFSCAFNYKGNIVITGS 406
>gi|124256480 APG16 autophagy 16-like isoform 1 [Homo sapiens]
Length = 607
Score = 52.8 bits (125), Expect = 8e-07
Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 12/106 (11%)
Query: 229 EILTCGRDGEPEPMQKLQDLVNRT----------PWKKCCFSGDGEYIVAGSARQHALYI 278
E+L+C RD + + + + +T W + FS DG Y+ AGSA + +LYI
Sbjct: 502 ELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSA-EGSLYI 560
Query: 279 WEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSI-WAQ 323
W G + K+L + VAW P + S+ G ++ WAQ
Sbjct: 561 WSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQ 606
Score = 33.9 bits (76), Expect = 0.39
Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Query: 3 LELLESFGQNYPEEADGTLDCISMALTCT-FNRWGTLLAVGCNDGRIVIWDFLTRGIAKI 61
++L E FG+ E G+L + +T F+ G+ L ND IW +
Sbjct: 346 VKLWEVFGEKC--EFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHT 403
Query: 62 ISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDC 100
++ H V S + D ++VS S D + WD+ S C
Sbjct: 404 LTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVC 442
>gi|124256478 APG16 autophagy 16-like isoform 2 [Homo sapiens]
Length = 588
Score = 52.8 bits (125), Expect = 8e-07
Identities = 32/106 (30%), Positives = 50/106 (47%), Gaps = 12/106 (11%)
Query: 229 EILTCGRDGEPEPMQKLQDLVNRT----------PWKKCCFSGDGEYIVAGSARQHALYI 278
E+L+C RD + + + + +T W + FS DG Y+ AGSA + +LYI
Sbjct: 483 ELLSCSRDDLLKVIDLRTNAIKQTFSAPGFKCGSDWTRVVFSPDGSYVAAGSA-EGSLYI 541
Query: 279 WEKSIGNLVKILHGTRGELLLDVAWHPVRPIIASISSGVVSI-WAQ 323
W G + K+L + VAW P + S+ G ++ WAQ
Sbjct: 542 WSVLTGKVEKVLSKQHSSSINAVAWSPSGSHVVSVDKGCKAVLWAQ 587
Score = 33.9 bits (76), Expect = 0.39
Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 3/99 (3%)
Query: 3 LELLESFGQNYPEEADGTLDCISMALTCT-FNRWGTLLAVGCNDGRIVIWDFLTRGIAKI 61
++L E FG+ E G+L + +T F+ G+ L ND IW +
Sbjct: 327 VKLWEVFGEKC--EFKGSLSGSNAGITSIEFDSAGSYLLAASNDFASRIWTVDDYRLRHT 384
Query: 62 ISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDC 100
++ H V S + D ++VS S D + WD+ S C
Sbjct: 385 LTGHSGKVLSAKFLLDNARIVSGSHDRTLKLWDLRSKVC 423
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 50.1 bits (118), Expect = 5e-06
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Query: 32 FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVS 91
F+ +G +A G D I +WD +G H V L +S DG L SA+ D+ V
Sbjct: 113 FHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVK 172
Query: 92 QWDVLSGDCDQRF-RFPSPILKVQYHPRD 119
WD+ +G F P+ V++HP +
Sbjct: 173 LWDLTAGKMMSEFPGHTGPVNVVEFHPNE 201
Score = 41.6 bits (96), Expect = 0.002
Identities = 49/246 (19%), Positives = 86/246 (34%), Gaps = 65/246 (26%)
Query: 38 LLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLS 97
L+ G G I +WD I + + H +CSL + G + S S D + WD+
Sbjct: 77 LIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRR 136
Query: 98 GDCDQRFRFPSPILK-VQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVV 156
C R+R S ++ +++ P D K + DD +
Sbjct: 137 KGCVFRYRGHSQAVRCLRFSP---------------------DGKWLASAADDHT----- 170
Query: 157 ASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTSNTTAIKSIEFARKGSCFLIN 216
DL A ++ +T + +EF
Sbjct: 171 -----------------------VKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASG 207
Query: 217 TADRIIRVYDGR--EILTCGRDGEPEPMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQH 274
++DR IR +D ++++C +GEP P++ + F+ DG + +G
Sbjct: 208 SSDRTIRFWDLEKFQVVSC-IEGEPGPVRSV------------LFNPDGCCLYSGCQDSL 254
Query: 275 ALYIWE 280
+Y WE
Sbjct: 255 RVYGWE 260
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/101 (23%), Positives = 43/101 (42%), Gaps = 14/101 (13%)
Query: 25 SMALTCT-FNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVS 83
S A+ C F+ G LA +D + +WD + H PV + + + + L S
Sbjct: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206
Query: 84 ASTDNIVSQWDVLSGDCDQRFRF-------PSPILKVQYHP 117
S+D + WD+ ++F+ P P+ V ++P
Sbjct: 207 GSSDRTIRFWDL------EKFQVVSCIEGEPGPVRSVLFNP 241
>gi|32483361 apoptotic peptidase activating factor 1 isoform d [Homo
sapiens]
Length = 1205
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/217 (21%), Positives = 93/217 (42%), Gaps = 20/217 (9%)
Query: 28 LTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSA--S 85
L C F+ +A D ++ IW+ +T + H V ++ H L+ A S
Sbjct: 661 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS 720
Query: 86 TDNIVSQWDVLSGDC-DQRFRFPSPILKVQYHPRDQ--------NKVLVCPMKSAPVMLT 136
+D + WD+ +C + F + + ++ P D+ + + SA +
Sbjct: 721 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 780
Query: 137 LSDSKHVVLPVDDDSDLNVV---ASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTT 193
++ + + D D+ V+ S+ G I AK KI + TDS+ VA R
Sbjct: 781 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVA-AKNKIFLWNTDSRSKVADCR--- 836
Query: 194 GTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREI 230
+ + + + F+ GS FL ++ D+ IR+++ +++
Sbjct: 837 --GHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKV 871
Score = 37.4 bits (85), Expect = 0.035
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 10/76 (13%)
Query: 37 TLLAVGCNDGRIVIWDFLTRGIAKI--------ISAHIHPVCSLCWSRDGHKLVSASTDN 88
TLLA G ++G I IW+ + + + H V LC+S DG L+SA
Sbjct: 1097 TLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--G 1154
Query: 89 IVSQWDVLSGDCDQRF 104
+ W+V++G+ Q F
Sbjct: 1155 YIKWWNVVTGESSQTF 1170
>gi|4502123 apoptotic peptidase activating factor 1 isoform b [Homo
sapiens]
Length = 1194
Score = 48.5 bits (114), Expect = 2e-05
Identities = 47/217 (21%), Positives = 93/217 (42%), Gaps = 20/217 (9%)
Query: 28 LTCTFNRWGTLLAVGCNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSA--S 85
L C F+ +A D ++ IW+ +T + H V ++ H L+ A S
Sbjct: 650 LCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNSSHHLLLATGS 709
Query: 86 TDNIVSQWDVLSGDC-DQRFRFPSPILKVQYHPRDQ--------NKVLVCPMKSAPVMLT 136
+D + WD+ +C + F + + ++ P D+ + + SA +
Sbjct: 710 SDCFLKLWDLNQKECRNTMFGHTNSVNHCRFSPDDKLLASCSADGTLKLWDATSANERKS 769
Query: 137 LSDSKHVVLPVDDDSDLNVV---ASFDRRGEYIYTGNAKGKILVLKTDSQDLVASFRVTT 193
++ + + D D+ V+ S+ G I AK KI + TDS+ VA R
Sbjct: 770 INVKQFFLNLEDPQEDMEVIVKCCSWSADGARIMVA-AKNKIFLWNTDSRSKVADCR--- 825
Query: 194 GTSNTTAIKSIEFARKGSCFLINTADRIIRVYDGREI 230
+ + + + F+ GS FL ++ D+ IR+++ +++
Sbjct: 826 --GHLSWVHGVMFSPDGSSFLTSSDDQTIRLWETKKV 860
Score = 37.4 bits (85), Expect = 0.035
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 10/76 (13%)
Query: 37 TLLAVGCNDGRIVIWDFLTRGIAKI--------ISAHIHPVCSLCWSRDGHKLVSASTDN 88
TLLA G ++G I IW+ + + + H V LC+S DG L+SA
Sbjct: 1086 TLLATGDDNGEIRIWNVSNGELLHLCAPLSEEGAATHGGWVTDLCFSPDGKMLISAG--G 1143
Query: 89 IVSQWDVLSGDCDQRF 104
+ W+V++G+ Q F
Sbjct: 1144 YIKWWNVVTGESSQTF 1159
>gi|21541824 transducin-like enhancer protein 1 [Homo sapiens]
Length = 770
Score = 48.5 bits (114), Expect = 2e-05
Identities = 45/189 (23%), Positives = 78/189 (41%), Gaps = 19/189 (10%)
Query: 43 CNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQ 102
C+DG I +WD + + + H + S DG KL + DN V WD+ G Q
Sbjct: 593 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 652
Query: 103 RFRFPSPILKVQYHPRDQNKVLVCPMKSAPVMLTLSDSKHVVLPVDDDSDLNVVASFDRR 162
+ F S I + Y P + L M+S+ V + HV P D L++ S
Sbjct: 653 QHDFTSQIFSLGYCP--TGEWLAVGMESSNV-----EVLHVNKP--DKYQLHLHESCVLS 703
Query: 163 GEYIYTGNAKGKILVLKTDSQDLVASFRVTTGTS-----NTTAIKSIEFARKGSCFLINT 217
++ Y G + T +L+ ++R G S ++++ S + + + +
Sbjct: 704 LKFAYCGK-----WFVSTGKDNLLNAWRTPYGASIFQSKESSSVLSCDISVDDKYIVTGS 758
Query: 218 ADRIIRVYD 226
D+ VY+
Sbjct: 759 GDKKATVYE 767
>gi|34915994 transducin-like enhancer protein 4 [Homo sapiens]
Length = 773
Score = 48.1 bits (113), Expect = 2e-05
Identities = 24/75 (32%), Positives = 34/75 (45%)
Query: 43 CNDGRIVIWDFLTRGIAKIISAHIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQ 102
C+DG I +WD + + + H + S DG KL + DN V WD+ G Q
Sbjct: 596 CSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWTGGLDNTVRSWDLREGRQLQ 655
Query: 103 RFRFPSPILKVQYHP 117
+ F S I + Y P
Sbjct: 656 QHDFTSQIFSLGYCP 670
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.133 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,658,548
Number of Sequences: 37866
Number of extensions: 1150977
Number of successful extensions: 6158
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 216
Number of HSP's successfully gapped in prelim test: 315
Number of HSP's that attempted gapping in prelim test: 4530
Number of HSP's gapped (non-prelim): 1551
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.