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Search of human proteins with 53692189
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|53692189 adipocyte enhancer binding protein 1 precursor
[Homo sapiens]
(1158 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo... 2420 0.0
gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sap... 781 0.0
gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens] 660 0.0
gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sap... 350 6e-96
gi|4503009 carboxypeptidase E preproprotein [Homo sapiens] 343 7e-94
gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens] 342 1e-93
gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens] 342 1e-93
gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens] 342 1e-93
gi|22202611 carboxypeptidase D precursor [Homo sapiens] 310 4e-84
gi|53832021 carboxypeptidase M precursor [Homo sapiens] 216 1e-55
gi|38327526 carboxypeptidase M precursor [Homo sapiens] 216 1e-55
gi|6631081 carboxypeptidase M precursor [Homo sapiens] 216 1e-55
gi|10518506 coagulation factor VIII isoform b precursor [Homo sa... 102 2e-21
gi|4503647 coagulation factor VIII isoform a precursor [Homo sap... 102 2e-21
gi|31317224 EGF-like repeats and discoidin I-like domains-contai... 102 2e-21
gi|66864913 neuropilin 1 isoform c [Homo sapiens] 96 3e-19
gi|66912178 neuropilin 1 isoform b [Homo sapiens] 96 3e-19
gi|182508169 neuropilin 1 isoform a [Homo sapiens] 96 3e-19
gi|105990535 coagulation factor V precursor [Homo sapiens] 93 1e-18
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens] 93 1e-18
gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens] 93 1e-18
gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens] 93 1e-18
gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens] 93 1e-18
gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens] 93 1e-18
gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens] 93 1e-18
gi|110349719 titin isoform N2-A [Homo sapiens] 92 4e-18
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 90 1e-17
gi|62420886 discoidin domain receptor family, member 2 precursor... 88 4e-17
gi|62420884 discoidin domain receptor family, member 2 precursor... 88 4e-17
gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Ho... 87 7e-17
>gi|53692189 adipocyte enhancer binding protein 1 precursor [Homo
sapiens]
Length = 1158
Score = 2420 bits (6272), Expect = 0.0
Identities = 1158/1158 (100%), Positives = 1158/1158 (100%)
Query: 1 MAAVRGAPLLSCLLALLALCPGGRPQTVLTDDEIEEFLEGFLSELEPEPREDDVEAPPPP 60
MAAVRGAPLLSCLLALLALCPGGRPQTVLTDDEIEEFLEGFLSELEPEPREDDVEAPPPP
Sbjct: 1 MAAVRGAPLLSCLLALLALCPGGRPQTVLTDDEIEEFLEGFLSELEPEPREDDVEAPPPP 60
Query: 61 EPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKG 120
EPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKG
Sbjct: 61 EPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKG 120
Query: 121 KEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLE 180
KEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLE
Sbjct: 121 KEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLE 180
Query: 181 WPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIE 240
WPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIE
Sbjct: 181 WPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIE 240
Query: 241 REDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPP 300
REDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPP
Sbjct: 241 REDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPP 300
Query: 301 DYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPKEETDKWAVEK 360
DYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPKEETDKWAVEK
Sbjct: 301 DYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPKEETDKWAVEK 360
Query: 361 GKDHKEPRKGEELEEEWTPTEKVKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQ 420
GKDHKEPRKGEELEEEWTPTEKVKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQ
Sbjct: 361 GKDHKEPRKGEELEEEWTPTEKVKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQ 420
Query: 421 TGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSN 480
TGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSN
Sbjct: 421 TGATEDDYYDGAWCAEDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSN 480
Query: 481 DSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGC 540
DSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGC
Sbjct: 481 DSQTWVMYTNGYEEMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGC 540
Query: 541 SVAPVYSYYAQNEVVATDDLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIY 600
SVAPVYSYYAQNEVVATDDLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIY
Sbjct: 541 SVAPVYSYYAQNEVVATDDLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIY 600
Query: 601 AMEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDT 660
AMEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDT
Sbjct: 601 AMEISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDT 660
Query: 661 RIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPY 720
RIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPY
Sbjct: 661 RIHLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPY 720
Query: 721 RVPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPT 780
RVPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPT
Sbjct: 721 RVPNNNLPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPT 780
Query: 781 QEQLLAAAMAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYT 840
QEQLLAAAMAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYT
Sbjct: 781 QEQLLAAAMAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYT 840
Query: 841 GGMGIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTF 900
GGMGIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTF
Sbjct: 841 GGMGIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTF 900
Query: 901 MEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGY 960
MEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGY
Sbjct: 901 MEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGY 960
Query: 961 TPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQ 1020
TPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQ
Sbjct: 961 TPSAKTCNVDYDIGATQCNFILARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQ 1020
Query: 1021 RRLQHRLRLRAQMRLRRLNATTTLGPHTVPPTLPPAPATTLSTTIEPWGLIPPTTAGWEE 1080
RRLQHRLRLRAQMRLRRLNATTTLGPHTVPPTLPPAPATTLSTTIEPWGLIPPTTAGWEE
Sbjct: 1021 RRLQHRLRLRAQMRLRRLNATTTLGPHTVPPTLPPAPATTLSTTIEPWGLIPPTTAGWEE 1080
Query: 1081 SETETYTEVVTEFGTEVEPEFGTKVEPEFETQLEPEFETQLEPEFEEEEEEEKEEEIATG 1140
SETETYTEVVTEFGTEVEPEFGTKVEPEFETQLEPEFETQLEPEFEEEEEEEKEEEIATG
Sbjct: 1081 SETETYTEVVTEFGTEVEPEFGTKVEPEFETQLEPEFETQLEPEFEEEEEEEKEEEIATG 1140
Query: 1141 QAFPFTTVETYTVNFGDF 1158
QAFPFTTVETYTVNFGDF
Sbjct: 1141 QAFPFTTVETYTVNFGDF 1158
>gi|223005864 carboxypeptidase X (M14 family), member 2 [Homo sapiens]
Length = 756
Score = 781 bits (2017), Expect = 0.0
Identities = 396/762 (51%), Positives = 512/762 (67%), Gaps = 51/762 (6%)
Query: 267 ERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPPPQKP 326
+ +W P P EP ++ PPLP G+ + + P + P
Sbjct: 38 QEIWSREPYYARP--------EPELETFSPPLPAGPGEEWERRPQEPRPPKRATKPKKAP 89
Query: 327 DAERQTDEE----KEELKKPKKEDSSPKEETDKWAVEKGKDHKEPRKGEELEEEWTPTEK 382
E+ E K KK + SS K D DH E++ E
Sbjct: 90 KREKSAPEPPPPGKHSNKKVMRTKSSEKAAND--------DHSVRVAREDVRES------ 135
Query: 383 VKCPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQ 442
CPP+G+E+ +I D Q+ AS++ R+GLGA RGRLN+Q G E+D+YDGAWCA + Q
Sbjct: 136 --CPPLGLETLKITDFQLHASTVKRYGLGAHRGRLNIQAGINENDFYDGAWCAGRNDLQQ 193
Query: 443 WIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVD 502
WIEVD RR TRFTGVITQGR+S D+VT++ V SNDS TWV NG +M F GN +
Sbjct: 194 WIEVDARRLTRFTGVITQGRNSLWLSDWVTSYKVMVSNDSHTWVTVKNGSGDMIFEGNSE 253
Query: 503 KDTPVLSELPEPVVARFIRIYPLTW--NGSLCMRLEVLGCSVAPVYSYY-AQNEVVATDD 559
K+ PVL+ELP P+VAR+IRI P +W NGS+CMR+E+LGC + +YY +NE+ TDD
Sbjct: 254 KEIPVLNELPVPMVARYIRINPQSWFDNGSICMRMEILGCPLPDPNNYYHRRNEMTTTDD 313
Query: 560 LDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFR 619
LDF+HH+YK+MRQLMKVVNE CP ITR Y++GKS +GLK+YA+EISD+PGEHE+GEPEF
Sbjct: 314 LDFKHHNYKEMRQLMKVVNEMCPNITRIYNIGKSHQGLKLYAVEISDHPGEHEVGEPEFH 373
Query: 620 YTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQM 679
Y AG HGNEVLGRELLLLL+Q++C+EY N R+ LV++TRIH++PSLNPDGYE A +
Sbjct: 374 YIAGAHGNEVLGRELLLLLVQFVCQEYLARNARIVHLVEETRIHVLPSLNPDGYEKAYEG 433
Query: 680 GSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDAT 739
GSE G W+LG WT +G DI +FPDLN++LW AE+R+ VP +VPN+ + IPE +LS +AT
Sbjct: 434 GSELGGWSLGRWTHDGIDINNNFPDLNTLLWEAEDRQNVPRKVPNHYIAIPEWFLSENAT 493
Query: 740 VSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDE 799
V+ E RA+IAWMEK PFVLG NL GGE +V+YPYD+ R+P + Q
Sbjct: 494 VAAETRAVIAWMEKIPFVLGGNLQGGELVVAYPYDLVRSPWKTQ---------------- 537
Query: 800 VSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTIN 859
E TPD +FRWLA S+AS H +T+ R C +D+ G VNGA W+ G++N
Sbjct: 538 --EHTPTPDDHVFRWLAYSYASTHRLMTDARRRVCHTEDFQKEEGTVNGASWHTVAGSLN 595
Query: 860 DFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIP 919
DFSYLHTNC ELS Y+GCDK+PHES+LP EWENN+E+L+ FMEQVHRGIKG+V D G
Sbjct: 596 DFSYLHTNCFELSIYVGCDKYPHESQLPEEWENNRESLIVFMEQVHRGIKGLVRDSHGKG 655
Query: 920 IANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGATQCN 979
I NA ISV GINH ++TA+ GDYWR+LNPGEY VTA AEG+T S K C V YD+GAT+C+
Sbjct: 656 IPNAIISVEGINHDIRTANDGDYWRLLNPGEYVVTAKAEGFTASTKNCMVGYDMGATRCD 715
Query: 980 FILARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQR 1021
F L+++N RIREIM G +P+ P+R + + ++ +QR
Sbjct: 716 FTLSKTNMARIREIMEKFGKQPVSL--PARRLKLRGQKRRQR 755
Score = 34.7 bits (78), Expect = 0.54
Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 5/61 (8%)
Query: 103 PKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATK 162
P P E E P+ P+ PPK KPK+ P + P+ PP K K+++
Sbjct: 62 PAGPGEEWERRPQEPR-----PPKRATKPKKAPKREKSAPEPPPPGKHSNKKVMRTKSSE 116
Query: 163 K 163
K
Sbjct: 117 K 117
>gi|9994201 carboxypeptidase X, member 1 precursor [Homo sapiens]
Length = 734
Score = 660 bits (1702), Expect = 0.0
Identities = 330/631 (52%), Positives = 429/631 (67%), Gaps = 26/631 (4%)
Query: 379 PTEKVK--CPPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAE 436
P EK + CPP+G+ES R+ D+++ ASS GLG RGRLN+Q+G + D YDGAWCAE
Sbjct: 107 PAEKQETGCPPLGLESLRVSDSRLEASSSQSFGLGPHRGRLNIQSGLEDGDLYDGAWCAE 166
Query: 437 DDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEM- 495
+ W +VD TRF+GVITQGR+S D+VT++ V FSNDS+TW N M
Sbjct: 167 EQDADPWFQVDAGHPTRFSGVITQGRNSVWRYDWVTSYKVQFSNDSRTWWGSRNHSSGMD 226
Query: 496 -TFHGNVDKDTPVLSELPEPVVARFIRIYPLTW--NGSLCMRLEVLGCSVAPVYSYYAQN 552
F N D +TPVL+ LPEP VARFIR+ P TW G+ C+R E+L C V+ + +
Sbjct: 227 AVFPANSDPETPVLNLLPEPQVARFIRLLPQTWLQGGAPCLRAEILACPVSDPNDLFLEA 286
Query: 553 EVVATDD-LDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEH 611
+ D LDF+HH+YK MR+LMK V E+CP ITR YS+GKS +GLK+Y ME+SD PGEH
Sbjct: 287 PASGSSDPLDFQHHNYKAMRKLMKQVQEQCPNITRIYSIGKSYQGLKLYVMEMSDKPGEH 346
Query: 612 ELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPD 671
ELGEPE RY AG+HGNE LGRELLLLLMQ+LC E+ GNPRV L+ + RIHL+PS+NPD
Sbjct: 347 ELGEPEVRYVAGMHGNEALGRELLLLLMQFLCHEFLRGNPRVTRLLSEMRIHLLPSMNPD 406
Query: 672 GYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPE 731
GYE+A GSE WA G W + D+ +F DLN+ LW A++ VP+ VPN++LP+P
Sbjct: 407 GYEIAYHRGSELVGWAEGRWNNQSIDLNHNFADLNTPLWEAQDDGKVPHIVPNHHLPLPT 466
Query: 732 RYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAA 791
Y P+ATV+ E RA+I WM++ PFVL ANL+GGE +VSYP+DM RTP A
Sbjct: 467 YYTLPNATVAPETRAVIKWMKRIPFVLSANLHGGELVVSYPFDMTRTPW----------A 516
Query: 792 ARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKW 851
AR E TPD A+FRWL+ +A ++L + + R C +QD++ I+NGA W
Sbjct: 517 AR--------ELTPTPDDAVFRWLSTVYAGSNLAMQDTSRRPCHSQDFSVHGNIINGADW 568
Query: 852 NPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGV 911
+ G++NDFSYLHTNC E++ L CDKFPHE+ELP+EWENNK+ALLT++EQV GI GV
Sbjct: 569 HTVPGSMNDFSYLHTNCFEVTVELSCDKFPHENELPQEWENNKDALLTYLEQVRMGIAGV 628
Query: 912 VTD-EQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVD 970
V D + + IA+A I+V GINH V TA GGDYWR+L PG+Y VTA AEGY + C V
Sbjct: 629 VRDKDTELGIADAVIAVDGINHDVTTAWGGDYWRLLTPGDYMVTASAEGYHSVTRNCRVT 688
Query: 971 YDIGATQCNFILARSNWKRIREIMAMNGNRP 1001
++ G CNF+L ++ +R+RE++A P
Sbjct: 689 FEEGPFPCNFVLTKTPKQRLRELLAAGAKVP 719
>gi|4503011 carboxypeptidase N, polypeptide 1 precursor [Homo sapiens]
Length = 458
Score = 350 bits (897), Expect = 6e-96
Identities = 200/477 (41%), Positives = 272/477 (57%), Gaps = 46/477 (9%)
Query: 562 FRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYT 621
FRHH Y D+ + + V ECP ITR YS+G+S G +Y +E SD+PG HE EPE +Y
Sbjct: 23 FRHHRYDDLVRTLYKVQNECPGITRVYSIGRSVEGRHLYVLEFSDHPGIHEPLEPEVKYV 82
Query: 622 AGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGS 681
+HGNE LGREL+L L ++LC E+R+ N R+ L+QDTRIH++PS+NPDGYEVAA G
Sbjct: 83 GNMHGNEALGRELMLQLSEFLCEEFRNRNQRIVQLIQDTRIHILPSMNPDGYEVAAAQGP 142
Query: 682 EFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVS 741
+ +G G D+ +FPDLN+ ++ E+ Y PN++LP+P+ + S V
Sbjct: 143 NKPGYLVGRNNANGVDLNRNFPDLNTYIYYNEK-----YGGPNHHLPLPDNWKS---QVE 194
Query: 742 TEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEVS 801
E RA+I WM FVL ANL+GG + +YPYD + + A
Sbjct: 195 PETRAVIRWMHSFNFVLSANLHGGAVVANYPYDKSFEHRVRGVRRTA------------- 241
Query: 802 EAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDF 861
+ TPD +F+ LA ++ AH + + + G D GI NGA W + + DF
Sbjct: 242 -STPTPDDKLFQKLAKVYSYAHGWMFQGWNCGDYFPD-----GITNGASWYSLSKGMQDF 295
Query: 862 SYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIA 921
+YLHTNC E++ L CDKFP E EL REW N+EAL+ F+EQVH+GIKG+V DE +A
Sbjct: 296 NYLHTNCFEITLELSCDKFPPEEELQREWLGNREALIQFLEQVHQGIKGMVLDENYNNLA 355
Query: 922 NATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGATQCNFI 981
NA ISVSGINH V + GDY+R+L PG Y V+A A GY P T V T NF
Sbjct: 356 NAVISVSGINHDVTSGDHGDYFRLLLPGIYTVSATAPGYDPETVTVTVG-PAEPTLVNFH 414
Query: 982 LARSNWKRIREIMAMNGNRPIPHIDPSRPMTPQQRRLQQRRLQHRLRLRAQMRLRRL 1038
L RS IP + P R P +R + ++Q + R + +M +R+L
Sbjct: 415 LKRS----------------IPQVSPVR-RAPSRRHGVRAKVQPQAR-KKEMEMRQL 453
>gi|4503009 carboxypeptidase E preproprotein [Homo sapiens]
Length = 476
Score = 343 bits (879), Expect = 7e-94
Identities = 174/436 (39%), Positives = 256/436 (58%), Gaps = 27/436 (6%)
Query: 543 APVYSYYAQNEVVATDDLDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAM 602
AP + + D + F +H Y ++R+ + V +C I+R Y++G+S G ++ +
Sbjct: 32 APAAGMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGRELLVI 91
Query: 603 EISDNPGEHELGEPEFRYTAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRI 662
E+SDNPG HE GEPEF+Y +HGNE +GRELL+ L QYLC EY+ GN + +L+ TRI
Sbjct: 92 ELSDNPGVHEPGEPEFKYIGNMHGNEAVGRELLIFLAQYLCNEYQKGNETIVNLIHSTRI 151
Query: 663 HLVPSLNPDGYEVAAQMGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRV 722
H++PSLNPDG+E AA E +W +G +G D+ +FPDL+ +++ E+
Sbjct: 152 HIMPSLNPDGFEKAASQPGELKDWFVGRSNAQGIDLNRNFPDLDRIVYVNEKEGG----- 206
Query: 723 PNNN-LPIPERYLSPDATVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQ 781
PNN+ L ++ + + ++ E +A+I W+ PFVL ANL+GG+ + +YPYD R+
Sbjct: 207 PNNHLLKNMKKIVDQNTKLAPETKAVIHWIMDIPFVLSANLHGGDLVANYPYDETRS--- 263
Query: 782 EQLLAAAMAAARGEDEDEVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTG 841
E +PD AIF+ LA +++S + +++P R C+ D
Sbjct: 264 ----------------GSAHEYSSSPDDAIFQSLARAYSSFNPAMSDPNRPPCRKNDDDS 307
Query: 842 GM--GIVNGAKWNPRTGTINDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLT 899
G NG W G + DF+YL +NC E++ L C+KFP E L WE+NK +L++
Sbjct: 308 SFVDGTTNGGAWYSVPGGMQDFNYLSSNCFEITVELSCEKFPPEETLKTYWEDNKNSLIS 367
Query: 900 FMEQVHRGIKGVVTDEQGIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEG 959
++EQ+HRG+KG V D QG PIANATISV GI+H V +A GDYWR+L PG Y++TA A G
Sbjct: 368 YLEQIHRGVKGFVRDLQGNPIANATISVEGIDHDVTSAKDGDYWRLLIPGNYKLTASAPG 427
Query: 960 YTPSAKTCNVDYDIGA 975
Y K V Y A
Sbjct: 428 YLAITKKVAVPYSPAA 443
>gi|62388879 carboxypeptidase Z isoform 3 [Homo sapiens]
Length = 515
Score = 342 bits (877), Expect = 1e-93
Identities = 175/404 (43%), Positives = 243/404 (60%), Gaps = 25/404 (6%)
Query: 562 FRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYT 621
F HHSY M ++++ C + RTYS+G+S G ++ +E S PG+HEL EPE +
Sbjct: 48 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 107
Query: 622 AGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGS 681
IHGNEV GRE+L+ L QYLC EY GNPR++ L+ TRIHL+PS+NPDGYEVAA G+
Sbjct: 108 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 167
Query: 682 EFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVS 741
+ W G + D+ +FPDL S + E + ++++PIP+ Y V+
Sbjct: 168 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETR----GARSDHIPIPQHYWW--GKVA 221
Query: 742 TEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEVS 801
E +AI+ WM+ PFVL A+L+GG+ +VSYP+D ++ P +E++ +
Sbjct: 222 PETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFS--------------- 266
Query: 802 EAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDF 861
TPD +F+ L+ ++A H + + C G I+NGA W TG ++DF
Sbjct: 267 ---PTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRG-SIINGADWYSFTGGMSDF 322
Query: 862 SYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIA 921
+YLHTNC E++ LGC KFP E L W++NKE+LL F+E VHRGIKGVVTD+ G P+
Sbjct: 323 NYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVK 382
Query: 922 NATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAK 965
NA ISV GI H + TA GDYWR+L PG + V A A GY K
Sbjct: 383 NARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIK 426
>gi|62388875 carboxypeptidase Z isoform 2 precursor [Homo sapiens]
Length = 641
Score = 342 bits (877), Expect = 1e-93
Identities = 175/404 (43%), Positives = 243/404 (60%), Gaps = 25/404 (6%)
Query: 562 FRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYT 621
F HHSY M ++++ C + RTYS+G+S G ++ +E S PG+HEL EPE +
Sbjct: 174 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 233
Query: 622 AGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGS 681
IHGNEV GRE+L+ L QYLC EY GNPR++ L+ TRIHL+PS+NPDGYEVAA G+
Sbjct: 234 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 293
Query: 682 EFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVS 741
+ W G + D+ +FPDL S + E + ++++PIP+ Y V+
Sbjct: 294 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETR----GARSDHIPIPQHYWW--GKVA 347
Query: 742 TEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEVS 801
E +AI+ WM+ PFVL A+L+GG+ +VSYP+D ++ P +E++ +
Sbjct: 348 PETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFS--------------- 392
Query: 802 EAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDF 861
TPD +F+ L+ ++A H + + C G I+NGA W TG ++DF
Sbjct: 393 ---PTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRG-SIINGADWYSFTGGMSDF 448
Query: 862 SYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIA 921
+YLHTNC E++ LGC KFP E L W++NKE+LL F+E VHRGIKGVVTD+ G P+
Sbjct: 449 NYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVK 508
Query: 922 NATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAK 965
NA ISV GI H + TA GDYWR+L PG + V A A GY K
Sbjct: 509 NARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIK 552
>gi|62388877 carboxypeptidase Z isoform 1 [Homo sapiens]
Length = 652
Score = 342 bits (877), Expect = 1e-93
Identities = 175/404 (43%), Positives = 243/404 (60%), Gaps = 25/404 (6%)
Query: 562 FRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYT 621
F HHSY M ++++ C + RTYS+G+S G ++ +E S PG+HEL EPE +
Sbjct: 185 FSHHSYAQMVRVLRRTASRCAHVARTYSIGRSFDGRELLVIEFSSRPGQHELMEPEVKLI 244
Query: 622 AGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGS 681
IHGNEV GRE+L+ L QYLC EY GNPR++ L+ TRIHL+PS+NPDGYEVAA G+
Sbjct: 245 GNIHGNEVAGREMLIYLAQYLCSEYLLGNPRIQRLLNTTRIHLLPSMNPDGYEVAAAEGA 304
Query: 682 EFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVS 741
+ W G + D+ +FPDL S + E + ++++PIP+ Y V+
Sbjct: 305 GYNGWTSGRQNAQNLDLNRNFPDLTSEYYRLAETR----GARSDHIPIPQHYWW--GKVA 358
Query: 742 TEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEVS 801
E +AI+ WM+ PFVL A+L+GG+ +VSYP+D ++ P +E++ +
Sbjct: 359 PETKAIMKWMQTIPFVLSASLHGGDLVVSYPFDFSKHPQEEKMFS--------------- 403
Query: 802 EAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTINDF 861
TPD +F+ L+ ++A H + + C G I+NGA W TG ++DF
Sbjct: 404 ---PTPDEKMFKLLSRAYADVHPMMMDRSENRCGGNFLKRG-SIINGADWYSFTGGMSDF 459
Query: 862 SYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPIA 921
+YLHTNC E++ LGC KFP E L W++NKE+LL F+E VHRGIKGVVTD+ G P+
Sbjct: 460 NYLHTNCFEITVELGCVKFPPEEALYTLWQHNKESLLNFVETVHRGIKGVVTDKFGKPVK 519
Query: 922 NATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAK 965
NA ISV GI H + TA GDYWR+L PG + V A A GY K
Sbjct: 520 NARISVKGIRHDITTAPDGDYWRLLPPGIHIVIAQAPGYAKVIK 563
>gi|22202611 carboxypeptidase D precursor [Homo sapiens]
Length = 1380
Score = 310 bits (795), Expect = 4e-84
Identities = 175/430 (40%), Positives = 241/430 (56%), Gaps = 59/430 (13%)
Query: 561 DFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRY 620
DF HH + DM ++ E P ITR YSLGKS ++Y MEISDNPG HE GEPEF+Y
Sbjct: 500 DFHHHHFPDMEIFLRRFANEYPNITRLYSLGKSVESRELYVMEISDNPGVHEPGEPEFKY 559
Query: 621 TAGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMG 680
+HGNEV+GRELLL L++YLC+ + +P V LV +TRIHL+PS+NPDGYE +Q G
Sbjct: 560 IGNMHGNEVVGRELLLNLIEYLCKNFGT-DPEVTDLVHNTRIHLMPSMNPDGYE-KSQEG 617
Query: 681 SEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATV 740
+G FD+ +FPD +++
Sbjct: 618 DSIS--VIGRNNSNNFDLNRNFPD---------------------------QFVQITDPT 648
Query: 741 STEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEV 800
E A+++WM+ PFVL ANL+GG +V+YP+D +DE +
Sbjct: 649 QPETIAVMSWMKSYPFVLSANLHGGSLVVNYPFD--------------------DDEQGL 688
Query: 801 SEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGM---GIVNGAKWNPRTGT 857
+ ++PD A+F+ +A+S++ + ++ ++G Y GI NGA W G
Sbjct: 689 ATYSKSPDDAVFQQIALSYSKEN---SQMFQGRPCKNMYPNEYFPHGITNGASWYNVPGG 745
Query: 858 INDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTD-EQ 916
+ D++YL TNC E++ LGC K+P E ELP WE N+ +L+ FM+QVH+G++G V D
Sbjct: 746 MQDWNYLQTNCFEVTIELGCVKYPLEKELPNFWEQNRRSLIQFMKQVHQGVRGFVLDATD 805
Query: 917 GIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
G I NATISV+ INH V T GDYWR+L PG Y++TA A GY P K V + GA
Sbjct: 806 GRGILNATISVAEINHPVTTYKTGDYWRLLVPGTYKITASARGYNPVTKNVTVKSE-GAI 864
Query: 977 QCNFILARSN 986
Q NF L RS+
Sbjct: 865 QVNFTLVRSS 874
Score = 216 bits (549), Expect = 1e-55
Identities = 150/486 (30%), Positives = 226/486 (46%), Gaps = 78/486 (16%)
Query: 531 LCMRLEVLGCSVAPVYSYYAQNEVVATD--------DLDFRHHSYKDMRQLMKVVNEECP 582
L M L +LG S + A+ T D +H + L + P
Sbjct: 18 LLMCLLLLGSSARAAHIKKAEATTTTTSAGAEAAEGQFDRYYHEEELESALREAAAAGLP 77
Query: 583 TITRTYSLGKSSRGLKIYAMEIS-------------------DNPGEHELGEPEFRYTAG 623
+ R +S+G+S G ++ + ++ D G G P+ +
Sbjct: 78 GLARLFSIGRSVEGRPLWVLRLTAGLGSLIPEGDAGPDAAGPDAAGPLLPGRPQVKLVGN 137
Query: 624 IHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGSEF 683
+HG+E + R++L+ L + L YR G+PR+ L+ T ++L+PSLNPDG+E A + F
Sbjct: 138 MHGDETVSRQVLIYLARELAAGYRRGDPRLVRLLNTTDVYLLPSLNPDGFERAREGDCGF 197
Query: 684 GNW----ALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDAT 739
G+ A G G D+ FPD S P
Sbjct: 198 GDGGPSGASGRDNSRGRDLNRSFPDQFST------------------------GEPPALD 233
Query: 740 VSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDE 799
EVRA+I W+ +N FVL NL+GG + SYP+D + +
Sbjct: 234 EVPEVRALIEWIRRNKFVLSGNLHGGSVVASYPFDDS------------------PEHKA 275
Query: 800 VSEAQETPDHAIFRWLAISFASAH--LTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGT 857
+T D +F++LA ++AS H + EP+ G +D T GI NGA W G
Sbjct: 276 TGIYSKTSDDEVFKYLAKAYASNHPIMKTGEPHCPG--DEDETFKDGITNGAHWYDVEGG 333
Query: 858 INDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDE-Q 916
+ D++Y+ NC E++ L C K+P S+L +EWENN+E+L+T +E+VH G+KG V D
Sbjct: 334 MQDYNYVWANCFEITLELSCCKYPPASQLRQEWENNRESLITLIEKVHIGVKGFVKDSIT 393
Query: 917 GIPIANATISVSGINHGVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
G + NATISV+GINH + T GD++R+L PG Y +T GY P T V + AT
Sbjct: 394 GSGLENATISVAGINHNITTGRFGDFYRLLVPGTYNLTVVLTGYMPLTVTNVVVKEGPAT 453
Query: 977 QCNFIL 982
+ +F L
Sbjct: 454 EVDFSL 459
Score = 191 bits (485), Expect = 3e-48
Identities = 135/418 (32%), Positives = 200/418 (47%), Gaps = 69/418 (16%)
Query: 562 FRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFRYT 621
+R+HSYKD+ + ++ + P IT +LG+S+ I+++EIS+ P E EP+ R+
Sbjct: 931 YRYHSYKDLSEFLRGLVMNYPHITNLTNLGQSTEYRHIWSLEISNKPNVSEPEEPKIRFV 990
Query: 622 AGIHGNEVLGRELLLLLMQYLCREYRDGNPRVRSLVQDTRIHLVPSLNPDGYEVAAQMGS 681
AGIHGN +G ELLL L ++LC Y+ NP V LV TRI +VPSLNPDG E A +
Sbjct: 991 AGIHGNAPVGTELLLALAEFLCLNYKK-NPAVTQLVDRTRIVIVPSLNPDGRERAQEKDC 1049
Query: 682 EFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDATVS 741
+G G D+ DF NN P
Sbjct: 1050 ---TSKIGQTNARGKDLDTDF---------------------TNNASQP----------- 1074
Query: 742 TEVRAIIA-WMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDEDEV 800
E +AII ++K F L L+GG LV+YPYD P Q
Sbjct: 1075 -ETKAIIENLIQKQDFSLSVALDGGSMLVTYPYD---KPVQ------------------T 1112
Query: 801 SEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTIND 860
E +ET H LA +A+ H ++ D G++ GA+W+ G++ D
Sbjct: 1113 VENKETLKH-----LASLYANNHPSMHMGQPSCPNKSDENIPGGVMRGAEWHSHLGSMKD 1167
Query: 861 FSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGIPI 920
+S + +C E++ Y C FP + LP W +NK +LL+ + +VH+G+ G V D+ G PI
Sbjct: 1168 YSVTYGHCPEITVYTSCCYFPSAARLPSLWADNKRSLLSMLVEVHKGVHGFVKDKTGKPI 1227
Query: 921 ANATISVSGINHGVK--TASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
+ A I +N G+K T GG + +L PG + + A A+GY V +D ++
Sbjct: 1228 SKAVIV---LNEGIKVQTKEGGYFHVLLAPGVHNIIAIADGYQQQHSQVFVHHDAASS 1282
>gi|53832021 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 216 bits (550), Expect = 1e-55
Identities = 137/465 (29%), Positives = 221/465 (47%), Gaps = 69/465 (14%)
Query: 560 LDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFR 619
LDF +H + M +K V + ++T +S+GKS +G ++ + + P EH +G PEF+
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 620 YTAGIHGNEVLGRELLLLLMQYLCREYRDG-NPRVRSLVQDTRIHLVPSLNPDGYEVAAQ 678
Y A +HG+E +GRELLL L+ YL DG +P + +L+ TRIH++PS+NPDG+E +
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTS--DGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
Query: 679 MGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDA 738
+ ++G +D+ +FPD NN+
Sbjct: 136 PDCYY---SIGRENYNQYDLNRNFPDAFEY----------------NNV----------- 165
Query: 739 TVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDED 798
+ E A++ W++ FVL ANL+GG + SYP+D T
Sbjct: 166 SRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQAT-----------------G 208
Query: 799 EVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTI 858
+ TPD +F++LA ++AS + + +G G+ NG W P G +
Sbjct: 209 ALYSRSLTPDDDVFQYLAHTYASRNPNMK---KGDECKNKMNFPNGVTNGYSWYPLQGGM 265
Query: 859 NDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGI 918
D++Y+ C E++ L C K+P E +LP W NNK +L+ +++QVH G+KG V D+ G
Sbjct: 266 QDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGN 325
Query: 919 PIANATISVSGINH--GVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
P+ N + V H +T G+Y+ +L PG Y + G+ P T
Sbjct: 326 PLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPH-----------IT 374
Query: 977 QCNFILARSNWKRIRE--IMAMNGN-RPIPHIDPSRPMTPQQRRL 1018
+ N+ +++ ++ G IP +PS PM P R L
Sbjct: 375 KVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNL 419
>gi|38327526 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 216 bits (550), Expect = 1e-55
Identities = 137/465 (29%), Positives = 221/465 (47%), Gaps = 69/465 (14%)
Query: 560 LDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFR 619
LDF +H + M +K V + ++T +S+GKS +G ++ + + P EH +G PEF+
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 620 YTAGIHGNEVLGRELLLLLMQYLCREYRDG-NPRVRSLVQDTRIHLVPSLNPDGYEVAAQ 678
Y A +HG+E +GRELLL L+ YL DG +P + +L+ TRIH++PS+NPDG+E +
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTS--DGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
Query: 679 MGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDA 738
+ ++G +D+ +FPD NN+
Sbjct: 136 PDCYY---SIGRENYNQYDLNRNFPDAFEY----------------NNV----------- 165
Query: 739 TVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDED 798
+ E A++ W++ FVL ANL+GG + SYP+D T
Sbjct: 166 SRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQAT-----------------G 208
Query: 799 EVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTI 858
+ TPD +F++LA ++AS + + +G G+ NG W P G +
Sbjct: 209 ALYSRSLTPDDDVFQYLAHTYASRNPNMK---KGDECKNKMNFPNGVTNGYSWYPLQGGM 265
Query: 859 NDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGI 918
D++Y+ C E++ L C K+P E +LP W NNK +L+ +++QVH G+KG V D+ G
Sbjct: 266 QDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGN 325
Query: 919 PIANATISVSGINH--GVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
P+ N + V H +T G+Y+ +L PG Y + G+ P T
Sbjct: 326 PLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPH-----------IT 374
Query: 977 QCNFILARSNWKRIRE--IMAMNGN-RPIPHIDPSRPMTPQQRRL 1018
+ N+ +++ ++ G IP +PS PM P R L
Sbjct: 375 KVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNL 419
>gi|6631081 carboxypeptidase M precursor [Homo sapiens]
Length = 443
Score = 216 bits (550), Expect = 1e-55
Identities = 137/465 (29%), Positives = 221/465 (47%), Gaps = 69/465 (14%)
Query: 560 LDFRHHSYKDMRQLMKVVNEECPTITRTYSLGKSSRGLKIYAMEISDNPGEHELGEPEFR 619
LDF +H + M +K V + ++T +S+GKS +G ++ + + P EH +G PEF+
Sbjct: 18 LDFNYHRQEGMEAFLKTVAQNYSSVTHLHSIGKSVKGRNLWVLVVGRFPKEHRIGIPEFK 77
Query: 620 YTAGIHGNEVLGRELLLLLMQYLCREYRDG-NPRVRSLVQDTRIHLVPSLNPDGYEVAAQ 678
Y A +HG+E +GRELLL L+ YL DG +P + +L+ TRIH++PS+NPDG+E +
Sbjct: 78 YVANMHGDETVGRELLLHLIDYLVTS--DGKDPEITNLINSTRIHIMPSMNPDGFEAVKK 135
Query: 679 MGSEFGNWALGLWTEEGFDIFEDFPDLNSVLWGAEERKWVPYRVPNNNLPIPERYLSPDA 738
+ ++G +D+ +FPD NN+
Sbjct: 136 PDCYY---SIGRENYNQYDLNRNFPDAFEY----------------NNV----------- 165
Query: 739 TVSTEVRAIIAWMEKNPFVLGANLNGGERLVSYPYDMARTPTQEQLLAAAMAAARGEDED 798
+ E A++ W++ FVL ANL+GG + SYP+D T
Sbjct: 166 SRQPETVAVMKWLKTETFVLSANLHGGALVASYPFDNGVQAT-----------------G 208
Query: 799 EVSEAQETPDHAIFRWLAISFASAHLTLTEPYRGGCQAQDYTGGMGIVNGAKWNPRTGTI 858
+ TPD +F++LA ++AS + + +G G+ NG W P G +
Sbjct: 209 ALYSRSLTPDDDVFQYLAHTYASRNPNMK---KGDECKNKMNFPNGVTNGYSWYPLQGGM 265
Query: 859 NDFSYLHTNCLELSFYLGCDKFPHESELPREWENNKEALLTFMEQVHRGIKGVVTDEQGI 918
D++Y+ C E++ L C K+P E +LP W NNK +L+ +++QVH G+KG V D+ G
Sbjct: 266 QDYNYIWAQCFEITLELSCCKYPREEKLPSFWNNNKASLIEYIKQVHLGVKGQVFDQNGN 325
Query: 919 PIANATISVSGINH--GVKTASGGDYWRILNPGEYRVTAHAEGYTPSAKTCNVDYDIGAT 976
P+ N + V H +T G+Y+ +L PG Y + G+ P T
Sbjct: 326 PLPNVIVEVQDRKHICPYRTNKYGEYYLLLLPGSYIINVTVPGHDPH-----------IT 374
Query: 977 QCNFILARSNWKRIRE--IMAMNGN-RPIPHIDPSRPMTPQQRRL 1018
+ N+ +++ ++ G IP +PS PM P R L
Sbjct: 375 KVIIPEKSQNFSALKKDILLPFQGQLDSIPVSNPSCPMIPLYRNL 419
>gi|10518506 coagulation factor VIII isoform b precursor [Homo
sapiens]
Length = 216
Score = 102 bits (255), Expect = 2e-21
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 10/163 (6%)
Query: 387 PIGMESHRIEDNQIRASSMLRHGLGA---QRGRLNMQTGATEDDYYDGAWCAEDDARTQW 443
P+GMES I D QI ASS + + RL++Q + AW + + +W
Sbjct: 61 PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSN-------AWRPQVNNPKEW 113
Query: 444 IEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDK 503
++VD ++T + TGV TQG S + +V F + S D W ++ + F GN D
Sbjct: 114 LQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDS 173
Query: 504 DTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVAPVY 546
TPV++ L P++ R++RI+P +W + +R+EVLGC +Y
Sbjct: 174 FTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY 216
Score = 36.2 bits (82), Expect = 0.19
Identities = 15/46 (32%), Positives = 28/46 (60%)
Query: 497 FHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F GNVD + P++AR+IR++P ++ +R+E++GC +
Sbjct: 10 FFGNVDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDL 55
>gi|4503647 coagulation factor VIII isoform a precursor [Homo sapiens]
Length = 2351
Score = 102 bits (255), Expect = 2e-21
Identities = 54/163 (33%), Positives = 86/163 (52%), Gaps = 10/163 (6%)
Query: 387 PIGMESHRIEDNQIRASSMLRHGLGA---QRGRLNMQTGATEDDYYDGAWCAEDDARTQW 443
P+GMES I D QI ASS + + RL++Q + AW + + +W
Sbjct: 2196 PLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSN-------AWRPQVNNPKEW 2248
Query: 444 IEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNVDK 503
++VD ++T + TGV TQG S + +V F + S D W ++ + F GN D
Sbjct: 2249 LQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDS 2308
Query: 504 DTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVAPVY 546
TPV++ L P++ R++RI+P +W + +R+EVLGC +Y
Sbjct: 2309 FTPVVNSLDPPLLTRYLRIHPQSWVHQIALRMEVLGCEAQDLY 2351
Score = 63.9 bits (154), Expect = 8e-10
Identities = 46/162 (28%), Positives = 75/162 (46%), Gaps = 13/162 (8%)
Query: 384 KCP-PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQ 442
KC P+GM S I D QI AS ++G A + +G+ AW ++
Sbjct: 2039 KCQTPLGMASGHIRDFQITASG--QYGQWAPKLARLHYSGSIN------AWSTKEPF--S 2088
Query: 443 WIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEE--MTFHGN 500
WI+VD G+ TQG +++ F + +S D + W Y M F GN
Sbjct: 2089 WIKVDLLAPMIIHGIKTQGARQKFSSLYISQFIIMYSLDGKKWQTYRGNSTGTLMVFFGN 2148
Query: 501 VDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
VD + P++AR+IR++P ++ +R+E++GC +
Sbjct: 2149 VDSSGIKHNIFNPPIIARYIRLHPTHYSIRSTLRMELMGCDL 2190
>gi|31317224 EGF-like repeats and discoidin I-like
domains-containing protein 3 [Homo sapiens]
Length = 480
Score = 102 bits (254), Expect = 2e-21
Identities = 59/170 (34%), Positives = 92/170 (54%), Gaps = 19/170 (11%)
Query: 384 KCP-PIGMESHRIEDNQIRASSMLRHGLGAQR-----GRLNMQTGATEDDYYDGAWCAED 437
KC P+G+E I + QI ASS R G Q+ RLN + AW A +
Sbjct: 157 KCSGPLGIEGGIISNQQITASSTHRALFGLQKWYPYYARLNKKG-------LINAWTAAE 209
Query: 438 DARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMY----TNGYE 493
+ R WI+++ +R R TGVITQG +++ ++ + +SND +TW MY TN E
Sbjct: 210 NDRWPWIQINLQRKMRVTGVITQGAKRIGSPEYIKSYKIAYSNDGKTWAMYKVKGTN--E 267
Query: 494 EMTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSVA 543
+M F GN+D +TP + P+ A+++R+YP +R+E+LGC ++
Sbjct: 268 DMVFRGNIDNNTPYANSFTPPIKAQYVRLYPQVCRRHCTLRMELLGCELS 317
Score = 98.6 bits (244), Expect = 3e-20
Identities = 54/157 (34%), Positives = 85/157 (54%), Gaps = 3/157 (1%)
Query: 387 PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEV 446
P+GM+S I+D QI ASS+ R L + + AW + + ++QW++V
Sbjct: 322 PLGMKSGHIQDYQITASSIFRT-LNMDMFTWEPRKARLDKQGKVNAWTSGHNDQSQWLQV 380
Query: 447 DTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYE--EMTFHGNVDKD 504
D T+ TG+ITQG H FV ++ + +SND + W +Y + + + F GN D D
Sbjct: 381 DLLVPTKVTGIITQGAKDFGHVQFVGSYKLAYSNDGEHWTVYQDEKQRKDKVFQGNFDND 440
Query: 505 TPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCS 541
T + + P+ AR IRI P +W G + +R E+LGC+
Sbjct: 441 THRKNVIDPPIYARHIRILPWSWYGRITLRSELLGCT 477
>gi|66864913 neuropilin 1 isoform c [Homo sapiens]
Length = 609
Score = 95.5 bits (236), Expect = 3e-19
Identities = 55/166 (33%), Positives = 82/166 (49%), Gaps = 12/166 (7%)
Query: 380 TEKVKC-PPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDD 438
+E KC +GMES I +QI ASS A+R RLN Y + W +D
Sbjct: 270 SEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLN---------YPENGWTPGED 320
Query: 439 ARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEMT 496
+ +WI+VD T V TQG S +V T+ + S++ + W+ G + +
Sbjct: 321 SYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVL 380
Query: 497 FHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F GN + V++ P+P++ RF+RI P TW + MR EV GC +
Sbjct: 381 FQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKI 426
Score = 62.4 bits (150), Expect = 2e-09
Identities = 36/104 (34%), Positives = 56/104 (53%), Gaps = 4/104 (3%)
Query: 442 QWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTW--VMYTNGYEEMTFHG 499
+W+++D G+I QG + F+ F +G+SN+ W +M + + +F G
Sbjct: 483 EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEG 542
Query: 500 NVDKDTPVLSELPEPVVARFIRIYP-LTWNGSLCMRLEVLGCSV 542
N + DTP L P + RFIRIYP +G L +R+E+LGC V
Sbjct: 543 NNNYDTPELRTFP-ALSTRFIRIYPERATHGGLGLRMELLGCEV 585
>gi|66912178 neuropilin 1 isoform b [Homo sapiens]
Length = 644
Score = 95.5 bits (236), Expect = 3e-19
Identities = 55/166 (33%), Positives = 82/166 (49%), Gaps = 12/166 (7%)
Query: 380 TEKVKC-PPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDD 438
+E KC +GMES I +QI ASS A+R RLN Y + W +D
Sbjct: 270 SEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLN---------YPENGWTPGED 320
Query: 439 ARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEMT 496
+ +WI+VD T V TQG S +V T+ + S++ + W+ G + +
Sbjct: 321 SYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVL 380
Query: 497 FHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F GN + V++ P+P++ RF+RI P TW + MR EV GC +
Sbjct: 381 FQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKI 426
Score = 62.4 bits (150), Expect = 2e-09
Identities = 36/104 (34%), Positives = 56/104 (53%), Gaps = 4/104 (3%)
Query: 442 QWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTW--VMYTNGYEEMTFHG 499
+W+++D G+I QG + F+ F +G+SN+ W +M + + +F G
Sbjct: 483 EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEG 542
Query: 500 NVDKDTPVLSELPEPVVARFIRIYP-LTWNGSLCMRLEVLGCSV 542
N + DTP L P + RFIRIYP +G L +R+E+LGC V
Sbjct: 543 NNNYDTPELRTFP-ALSTRFIRIYPERATHGGLGLRMELLGCEV 585
>gi|182508169 neuropilin 1 isoform a [Homo sapiens]
Length = 923
Score = 95.5 bits (236), Expect = 3e-19
Identities = 55/166 (33%), Positives = 82/166 (49%), Gaps = 12/166 (7%)
Query: 380 TEKVKC-PPIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDD 438
+E KC +GMES I +QI ASS A+R RLN Y + W +D
Sbjct: 270 SEDFKCMEALGMESGEIHSDQITASSQYSTNWSAERSRLN---------YPENGWTPGED 320
Query: 439 ARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEMT 496
+ +WI+VD T V TQG S +V T+ + S++ + W+ G + +
Sbjct: 321 SYREWIQVDLGLLRFVTAVGTQGAISKETKKKYYVKTYKIDVSSNGEDWITIKEGNKPVL 380
Query: 497 FHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F GN + V++ P+P++ RF+RI P TW + MR EV GC +
Sbjct: 381 FQGNTNPTDVVVAVFPKPLITRFVRIKPATWETGISMRFEVYGCKI 426
Score = 62.4 bits (150), Expect = 2e-09
Identities = 36/104 (34%), Positives = 56/104 (53%), Gaps = 4/104 (3%)
Query: 442 QWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTW--VMYTNGYEEMTFHG 499
+W+++D G+I QG + F+ F +G+SN+ W +M + + +F G
Sbjct: 483 EWLQIDLGEEKIVRGIIIQGGKHRENKVFMRKFKIGYSNNGSDWKMIMDDSKRKAKSFEG 542
Query: 500 NVDKDTPVLSELPEPVVARFIRIYP-LTWNGSLCMRLEVLGCSV 542
N + DTP L P + RFIRIYP +G L +R+E+LGC V
Sbjct: 543 NNNYDTPELRTFP-ALSTRFIRIYPERATHGGLGLRMELLGCEV 585
>gi|105990535 coagulation factor V precursor [Homo sapiens]
Length = 2224
Score = 93.2 bits (230), Expect = 1e-18
Identities = 53/162 (32%), Positives = 83/162 (51%), Gaps = 13/162 (8%)
Query: 387 PIGMESHRIEDNQIRASSMLRHGLGAQ----RGRLNMQTGATEDDYYDGAWCAEDDARTQ 442
P+GME+ +IE+ QI ASS + G R RLN Q AW A+ + Q
Sbjct: 2069 PLGMENGKIENKQITASSFKKSWWGDYWEPFRARLNAQGRVN-------AWQAKANNNKQ 2121
Query: 443 WIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYT--NGYEEMTFHGN 500
W+E+D + + T +ITQG S + +V ++ + +S W Y + + F GN
Sbjct: 2122 WLEIDLLKIKKITAIITQGCKSLSSEMYVKSYTIHYSEQGVEWKPYRLKSSMVDKIFEGN 2181
Query: 501 VDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
+ V + P+++RFIR+ P TWN S+ +RLE+ GC +
Sbjct: 2182 TNTKGHVKNFFNPPIISRFIRVIPKTWNQSIALRLELFGCDI 2223
Score = 74.7 bits (182), Expect = 5e-13
Identities = 48/158 (30%), Positives = 75/158 (47%), Gaps = 6/158 (3%)
Query: 387 PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEV 446
P+G+ + I D+QI+AS L G RL + + A + A WI+V
Sbjct: 1910 PMGLSTGIISDSQIKASEFL----GYWEPRLARLNNGGSYNAWSVEKLAAEFASKPWIQV 1965
Query: 447 DTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGYEE--MTFHGNVDKD 504
D ++ TG+ TQG + + T F+V +S++ W ++ M F+GN D
Sbjct: 1966 DMQKEVIITGIQTQGAKHYLKSCYTTEFYVAYSSNQINWQIFKGNSTRNVMYFNGNSDAS 2025
Query: 505 TPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
T ++ P+VAR+IRI P +RLE+ GC V
Sbjct: 2026 TIKENQFDPPIVARYIRISPTRAYNRPTLRLELQGCEV 2063
>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
Length = 909
Score = 93.2 bits (230), Expect = 1e-18
Identities = 56/167 (33%), Positives = 84/167 (50%), Gaps = 11/167 (6%)
Query: 379 PTEKVKCP-PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAED 437
P E +C P+GMES RI + QI ASS G R Q D D W
Sbjct: 271 PLENFQCNVPLGMESGRIANEQISASSTYSDG------RWTPQQSRLHGD--DNGWTPNL 322
Query: 438 DARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEM 495
D+ ++++VD R T T + TQG S + +V ++ + S + + W++Y +G
Sbjct: 323 DSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHK 382
Query: 496 TFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F N D VL++L P++ RF+RI P TW+ + +RLE+ GC V
Sbjct: 383 VFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 429
Score = 57.4 bits (137), Expect = 8e-08
Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 16/162 (9%)
Query: 388 IGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVD 447
+GM S I D+QI ASS + RL ++ ++ A+ +W++VD
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLV----SSRSGWFPRIPQAQPGE--EWLQVD 491
Query: 448 TRRTTRFTGVITQGR---DSSIHDD---FVTTFFVGFSNDSQTW--VMYTNGYEEMTFHG 499
GVI QG DS + FV F V +S + + W + + F G
Sbjct: 492 LGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEG 551
Query: 500 NVDKDTPVLSELPEPVVARFIRIYPLTWN-GSLCMRLEVLGC 540
N+ DTP + +P+ A+++R+YP W+ + MRLEVLGC
Sbjct: 552 NMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGC 592
>gi|41872567 neuropilin 2 isoform 5 precursor [Homo sapiens]
Length = 901
Score = 93.2 bits (230), Expect = 1e-18
Identities = 56/167 (33%), Positives = 84/167 (50%), Gaps = 11/167 (6%)
Query: 379 PTEKVKCP-PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAED 437
P E +C P+GMES RI + QI ASS G R Q D D W
Sbjct: 271 PLENFQCNVPLGMESGRIANEQISASSTYSDG------RWTPQQSRLHGD--DNGWTPNL 322
Query: 438 DARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEM 495
D+ ++++VD R T T + TQG S + +V ++ + S + + W++Y +G
Sbjct: 323 DSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHK 382
Query: 496 TFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F N D VL++L P++ RF+RI P TW+ + +RLE+ GC V
Sbjct: 383 VFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 429
Score = 57.4 bits (137), Expect = 8e-08
Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 16/162 (9%)
Query: 388 IGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVD 447
+GM S I D+QI ASS + RL ++ ++ A+ +W++VD
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLV----SSRSGWFPRIPQAQPGE--EWLQVD 491
Query: 448 TRRTTRFTGVITQGR---DSSIHDD---FVTTFFVGFSNDSQTW--VMYTNGYEEMTFHG 499
GVI QG DS + FV F V +S + + W + + F G
Sbjct: 492 LGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEG 551
Query: 500 NVDKDTPVLSELPEPVVARFIRIYPLTWN-GSLCMRLEVLGC 540
N+ DTP + +P+ A+++R+YP W+ + MRLEVLGC
Sbjct: 552 NMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGC 592
>gi|41872562 neuropilin 2 isoform 1 precursor [Homo sapiens]
Length = 931
Score = 93.2 bits (230), Expect = 1e-18
Identities = 56/167 (33%), Positives = 84/167 (50%), Gaps = 11/167 (6%)
Query: 379 PTEKVKCP-PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAED 437
P E +C P+GMES RI + QI ASS G R Q D D W
Sbjct: 271 PLENFQCNVPLGMESGRIANEQISASSTYSDG------RWTPQQSRLHGD--DNGWTPNL 322
Query: 438 DARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEM 495
D+ ++++VD R T T + TQG S + +V ++ + S + + W++Y +G
Sbjct: 323 DSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHK 382
Query: 496 TFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F N D VL++L P++ RF+RI P TW+ + +RLE+ GC V
Sbjct: 383 VFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 429
Score = 57.4 bits (137), Expect = 8e-08
Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 16/162 (9%)
Query: 388 IGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVD 447
+GM S I D+QI ASS + RL ++ ++ A+ +W++VD
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLV----SSRSGWFPRIPQAQPGE--EWLQVD 491
Query: 448 TRRTTRFTGVITQGR---DSSIHDD---FVTTFFVGFSNDSQTW--VMYTNGYEEMTFHG 499
GVI QG DS + FV F V +S + + W + + F G
Sbjct: 492 LGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEG 551
Query: 500 NVDKDTPVLSELPEPVVARFIRIYPLTWN-GSLCMRLEVLGC 540
N+ DTP + +P+ A+++R+YP W+ + MRLEVLGC
Sbjct: 552 NMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGC 592
>gi|41872557 neuropilin 2 isoform 6 precursor [Homo sapiens]
Length = 555
Score = 93.2 bits (230), Expect = 1e-18
Identities = 56/167 (33%), Positives = 84/167 (50%), Gaps = 11/167 (6%)
Query: 379 PTEKVKCP-PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAED 437
P E +C P+GMES RI + QI ASS G R Q D D W
Sbjct: 271 PLENFQCNVPLGMESGRIANEQISASSTYSDG------RWTPQQSRLHGD--DNGWTPNL 322
Query: 438 DARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEM 495
D+ ++++VD R T T + TQG S + +V ++ + S + + W++Y +G
Sbjct: 323 DSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHK 382
Query: 496 TFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F N D VL++L P++ RF+RI P TW+ + +RLE+ GC V
Sbjct: 383 VFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 429
>gi|41872544 neuropilin 2 isoform 4 precursor [Homo sapiens]
Length = 906
Score = 93.2 bits (230), Expect = 1e-18
Identities = 56/167 (33%), Positives = 84/167 (50%), Gaps = 11/167 (6%)
Query: 379 PTEKVKCP-PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAED 437
P E +C P+GMES RI + QI ASS G R Q D D W
Sbjct: 271 PLENFQCNVPLGMESGRIANEQISASSTYSDG------RWTPQQSRLHGD--DNGWTPNL 322
Query: 438 DARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEM 495
D+ ++++VD R T T + TQG S + +V ++ + S + + W++Y +G
Sbjct: 323 DSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHK 382
Query: 496 TFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F N D VL++L P++ RF+RI P TW+ + +RLE+ GC V
Sbjct: 383 VFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 429
Score = 57.4 bits (137), Expect = 8e-08
Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 16/162 (9%)
Query: 388 IGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVD 447
+GM S I D+QI ASS + RL ++ ++ A+ +W++VD
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLV----SSRSGWFPRIPQAQPGE--EWLQVD 491
Query: 448 TRRTTRFTGVITQGR---DSSIHDD---FVTTFFVGFSNDSQTW--VMYTNGYEEMTFHG 499
GVI QG DS + FV F V +S + + W + + F G
Sbjct: 492 LGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEG 551
Query: 500 NVDKDTPVLSELPEPVVARFIRIYPLTWN-GSLCMRLEVLGC 540
N+ DTP + +P+ A+++R+YP W+ + MRLEVLGC
Sbjct: 552 NMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGC 592
>gi|41872533 neuropilin 2 isoform 2 precursor [Homo sapiens]
Length = 926
Score = 93.2 bits (230), Expect = 1e-18
Identities = 56/167 (33%), Positives = 84/167 (50%), Gaps = 11/167 (6%)
Query: 379 PTEKVKCP-PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAED 437
P E +C P+GMES RI + QI ASS G R Q D D W
Sbjct: 271 PLENFQCNVPLGMESGRIANEQISASSTYSDG------RWTPQQSRLHGD--DNGWTPNL 322
Query: 438 DARTQWIEVDTRRTTRFTGVITQGRDSSIHDD--FVTTFFVGFSNDSQTWVMYTNGYEEM 495
D+ ++++VD R T T + TQG S + +V ++ + S + + W++Y +G
Sbjct: 323 DSNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWMVYRHGKNHK 382
Query: 496 TFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F N D VL++L P++ RF+RI P TW+ + +RLE+ GC V
Sbjct: 383 VFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLELFGCRV 429
Score = 57.4 bits (137), Expect = 8e-08
Identities = 49/162 (30%), Positives = 76/162 (46%), Gaps = 16/162 (9%)
Query: 388 IGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEVD 447
+GM S I D+QI ASS + RL ++ ++ A+ +W++VD
Sbjct: 438 LGMLSGLIADSQISASSTQEYLWSPSAARLV----SSRSGWFPRIPQAQPGE--EWLQVD 491
Query: 448 TRRTTRFTGVITQGR---DSSIHDD---FVTTFFVGFSNDSQTW--VMYTNGYEEMTFHG 499
GVI QG DS + FV F V +S + + W + + F G
Sbjct: 492 LGTPKTVKGVIIQGARGGDSITAVEARAFVRKFKVSYSLNGKDWEYIQDPRTQQPKLFEG 551
Query: 500 NVDKDTPVLSELPEPVVARFIRIYPLTWN-GSLCMRLEVLGC 540
N+ DTP + +P+ A+++R+YP W+ + MRLEVLGC
Sbjct: 552 NMHYDTPDIRRF-DPIPAQYVRVYPERWSPAGIGMRLEVLGC 592
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 91.7 bits (226), Expect = 4e-18
Identities = 103/388 (26%), Positives = 161/388 (41%), Gaps = 50/388 (12%)
Query: 25 PQTVLTDDEIEEFLEGFLSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAE 84
P+ V ++E+ +E +L E E E ++ E E P + P K P +
Sbjct: 9905 PEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVI--------PVKVPEVPRK 9956
Query: 85 VPPEKTKD----KGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATK 140
PE+ K K K+ K P+VPK+ E P K KEKPP A K P +
Sbjct: 9957 PVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPK-KEKPPPAKVPEVPKKPVPEE 10015
Query: 141 KPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGA 200
K PK + P K P+ KKP K+ P+ AP + P P P ++
Sbjct: 10016 KVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPT 10075
Query: 201 PLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQI--EREDYEDFEYIRRQKQPRP 258
P+ + P + + RE P P ++ + + ++I E E + E + +++
Sbjct: 10076 PVPKKVEAPPPKV-PKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVL 10134
Query: 259 PPSRRRRPERVWPEPPEEKAPAP----------APEERIEPPVKPLLP-PLP-PDY---- 302
P PE P EE+ P PEE + P VKP +P P P P+
Sbjct: 10135 PEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKV 10194
Query: 303 -GDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPKEETDKWAVEKG 361
VIP ++ PP + P+ ++ +E++ L PK+E+ P E T+
Sbjct: 10195 TEKKVVIPKKEE------APPAKVPEVPKKVEEKRIIL--PKEEEVLPVEVTE------- 10239
Query: 362 KDHKEPRKGEELEEEWTPTEKVK--CPP 387
+ +EP EE+ EE E+V+ PP
Sbjct: 10240 EPEEEPISEEEIPEEPPSIEEVEEVAPP 10267
Score = 82.8 bits (203), Expect = 2e-15
Identities = 106/398 (26%), Positives = 153/398 (38%), Gaps = 73/398 (18%)
Query: 33 EIEEFLEGFLSELEPEPR------------EDDVEAPPPPEPTPRVRKAQAGGKPGKRPG 80
E+EEF++ +E E R ++VE P+ P+ + P K+P
Sbjct: 10397 EVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPP 10456
Query: 81 TAA---EVPPEKTKDKGKKGKKDKGPKVPKESLEGSPR-PPKKGKEK-PPKATKKPKEKP 135
T + PP K + KK ++ +VP+E PR PP K E PPK K+ P
Sbjct: 10457 TKVVPRKEPPAKVPEVPKKIVVEEKVRVPEE-----PRVPPTKVPEVLPPKEVVPEKKVP 10511
Query: 136 PKATKKPKEKPPKATKKPKE---------KPPKATKKPPS--GKRPPILAPSETLEWPLP 184
KKP+ PPK + PKE PPK + PP+ + P P + + +P
Sbjct: 10512 VPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIP 10571
Query: 185 PPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDY 244
P P P E+P+ AP +E E + P++ P +
Sbjct: 10572 PKPESPPPEVPE---AP---------KEVVPEKKVPAAPPKKPEVTPV--------KVPE 10611
Query: 245 EDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPPDYGD 304
E + +K P PPP + P PE P+ P E I P KP PP P + +
Sbjct: 10612 APKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPP--KPESPP-PEVFEE 10668
Query: 305 GYVIPNYDDMDYYFGPP----------PPQKPDAERQTD---EEKEELKKPKKEDSSPKE 351
+ + P PP+KP E++ +K EL P K PKE
Sbjct: 10669 PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPEL-PPVKVPEVPKE 10727
Query: 352 ---ETDKWAVEKGKDHKEPRKGEELEEEWTPTEKVKCP 386
E V K P K E+ +E P +KV P
Sbjct: 10728 VVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765
Score = 80.9 bits (198), Expect = 7e-15
Identities = 114/391 (29%), Positives = 150/391 (38%), Gaps = 109/391 (27%)
Query: 25 PQTVLTDDEIEEFLEGFLSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAE 84
P+ V ++ E +E EPEP PP +P P +KA A K+P E
Sbjct: 10669 PEEVALEEPPAEVVE------EPEPAAPPQVTVPPKKPVPE-KKAPA--VVAKKP----E 10715
Query: 85 VPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKE 144
+PP K P+VPKE + P KK P KKP+ P K + PKE
Sbjct: 10716 LPPVKV------------PEVPKEVV-----PEKK---VPLVVPKKPEAPPAKVPEVPKE 10755
Query: 145 -------KPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEEL-PQ 196
PK + P K P+ KKP ++P + P E E P PP PEE+ P+
Sbjct: 10756 VVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP-ERAESP-PPEVYEEPEEIAPE 10813
Query: 197 EGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQP 256
E AP E +P P E E+P +
Sbjct: 10814 EEIAP----------------EEEKPVPVAEEEEPEV----------------------- 10834
Query: 257 RPPPSRRRRPERVWPE-------PPEEKAP-APAPEERIE-PPVKPLLPPLPPDYGDGYV 307
PPP+ P+++ PE PE P P PE+ IE P +KP PP PP
Sbjct: 10835 -PPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPP------A 10887
Query: 308 IPNYDDMDYYFG-PPPPQKPDAERQTDEEKEEL---------KKPKKEDSSPKEETDKWA 357
P D + F P+K E+ EK EL KK +K K E +
Sbjct: 10888 PPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEV 10947
Query: 358 VEKGKDHKEPRKGEELEEEWTPTEKVKCPPI 388
V K K P + EE + E EKVK P +
Sbjct: 10948 VLKSVLRKRPEE-EEPKVEPKKLEKVKKPAV 10977
Score = 78.6 bits (192), Expect = 3e-14
Identities = 105/408 (25%), Positives = 149/408 (36%), Gaps = 97/408 (23%)
Query: 44 ELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAA--EVPPEKTKDKGKKGKKDK 101
E+ PE + V P P +V + P K+ EVPP K + KK ++
Sbjct: 10727 EVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEE 10786
Query: 102 GPKVPKESLEGSPRP----------------PKKGKEKPPKATKKPKEKPPKATKKPK-- 143
P VP SP P P++ K P ++P+ PP ++PK
Sbjct: 10787 KPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKI 10846
Query: 144 --EKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEEL------- 194
EK KKP+ PPK + P P L P P PPPP+P E++
Sbjct: 10847 IPEKKVPVIKKPEAPPPKEPE-PEKVIEKPKLKPR-----PPPPPPAPPKEDVKEKIFQL 10900
Query: 195 --------PQEGGAPLS---NNWQNPGEETHVEAR--EHQPEPEEETEQPTLDYNDQIER 241
P++ P + PG E V E +PEP+EE ++ E
Sbjct: 10901 KAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEE 10960
Query: 242 E---DYEDFEYIRRQKQPRPPPSRR---------RRPERVWPEP---PEEK--APAPAPE 284
E + + E +++ P PPP + + ER PEP PE K P PAPE
Sbjct: 10961 EPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPE 11020
Query: 285 ERIEP-----PVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPPPQKPDAERQTDEEKEEL 339
+ +P +KP PP+ P+ P P +K E
Sbjct: 11021 PKPKPEAEVKTIKP--PPVEPE-------------------PTPIAAPVTVPVVGKKAEA 11059
Query: 340 KKPKKEDSSPKEETDKWAVEKGKDHKEPRKGEELEEEWTPTEKVKCPP 387
K PK+E + PK KG K P E + P + PP
Sbjct: 11060 KAPKEEAAKPKGPI------KGVPKKTPSPIEAERRKLRPGSGGEKPP 11101
Score = 73.9 bits (180), Expect = 8e-13
Identities = 97/401 (24%), Positives = 153/401 (38%), Gaps = 95/401 (23%)
Query: 44 ELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGP 103
E+ EP E+ + PE P + + + EV P + P
Sbjct: 10236 EVTEEPEEEPISEEEIPEEPPSIEEVE-------------EVAPPRV------------P 10270
Query: 104 KVPKESLEGSPRP-PKKGKEKPPKATKK-PKEKPPKATKKPKEKPPKATKKPKEKPPKAT 161
+V K+++ +P P PKK + P K +KK P+EK P +K + P K + PK+ P K
Sbjct: 10271 EVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKV 10330
Query: 162 KKPPSGKRPPI-----------------LAPSETLEWPLPPPPSPGPEELPQEGGAPLSN 204
P PP + E LE + EE+P+E
Sbjct: 10331 LVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEV---VEAEVEEIPEEEEFHEVE 10387
Query: 205 NWQNPGE----ETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPP 260
+ GE E ++ +H+ E E E+ + E E+ E FE +P+ PP
Sbjct: 10388 EYFEEGEFHEVEEFIKLEQHRVEEEHRVEK-VHRVIEVFEAEEVEVFE------KPKAPP 10440
Query: 261 SRRRRPERVWP--EPPEEKAPAPAP-------------EERIEPPVKPLLPP--LPPDYG 303
E++ P +PP + P P EE++ P +P +PP +P
Sbjct: 10441 KGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLP 10500
Query: 304 DGYVIPNYDDMDYYFGP------PPPQKPDAERQ-TDEEKEELKKPKKEDSSPKE--ETD 354
V+P + P PPP+ P+A ++ E+K + PKK + P + E
Sbjct: 10501 PKEVVP---EKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVP 10557
Query: 355 KWAVEK--------GKDHKEPRKGEELEEEWTPTEKVKCPP 387
K AV + K P + E +E P +KV P
Sbjct: 10558 KAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAP 10598
Score = 72.4 bits (176), Expect = 2e-12
Identities = 103/426 (24%), Positives = 160/426 (37%), Gaps = 79/426 (18%)
Query: 34 IEEFLEGFLSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDK 93
+EE L +E EP E P++ P K P ++ PEK K
Sbjct: 9536 VEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEK-KVP 9594
Query: 94 GKKGKKDK--GPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKK---------- 141
KK+K PKVP+E P+ P K+ PPK K + P K T++
Sbjct: 9595 APVPKKEKVPPPKVPEE-----PKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKV 9649
Query: 142 -----PKEKPPKA-------TKKPKEK----PPKATKKPPSG----KRPPILAPSETLEW 181
KE PPKA P+EK PK ++PP+ ++ + ++E
Sbjct: 9650 LVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEA 9709
Query: 182 PL--PPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYN--D 237
P P P +E L + E E E E E +PT +Y+ +
Sbjct: 9710 PKREPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYE 9769
Query: 238 QIEREDYEDF----EYIRRQKQPRP---------PPSRRRRPERVWPEP-PEEKAPAPAP 283
+ E +YE + EYI ++P P P + P +V + PEEK P P P
Sbjct: 9770 EYEEREYERYEEHEEYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIP 9829
Query: 284 EERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPP----PQKPD---AERQTDEEK 336
++ PP P +P P + + + + P P KP AE + +
Sbjct: 9830 KKLKPPP--PKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPR 9887
Query: 337 EELKKPKKEDSSPKE--------------ETDKWAVEKGKDHKEPRKGEELEEEWTPTEK 382
+E+ P + PKE +++ VE+ +++ + EEE P
Sbjct: 9888 KEVAPPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIP 9947
Query: 383 VKCPPI 388
VK P +
Sbjct: 9948 VKVPEV 9953
Score = 69.7 bits (169), Expect = 2e-11
Identities = 100/398 (25%), Positives = 155/398 (38%), Gaps = 56/398 (14%)
Query: 49 PREDDVEAPPPPE---PTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKG--- 102
P+ +V P PE P P +K +A P K P V E+ + ++
Sbjct: 9342 PKVPEVPKKPVPEEKIPVPVAKKKEA--PPAKVPEVQKGVVTEEKITIVTQREESPPPAV 9399
Query: 103 PKVPKESLEGSPRP-PKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKAT 161
P++PK+ + +P P+K +E PP K P +K P A K P PP+A
Sbjct: 9400 PEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKKAP---PPRAE 9456
Query: 162 KKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNPGEETHVEAREH- 220
+ E L + +P E+ E W EE V +
Sbjct: 9457 VSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAE------EEWSYSEEEEGVSISVYR 9510
Query: 221 QPEPEEETEQPTLDYNDQIEREDY---------------EDFEYIRRQK-----QPRPPP 260
+ E EEE E +Y E E+Y E E RQ+ +P+ P
Sbjct: 9511 EEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIVLKPKIPA 9570
Query: 261 SRRRRPERVWPEP-----PEEKAPAPAP-EERIEPPVKPLLPPLPPDYGDGYVIPNYDDM 314
P PE PE+K PAP P +E++ PP P P P + V P M
Sbjct: 9571 KIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKP--VPEKKVPPKVIKM 9628
Query: 315 DYYFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPK---EETDKWAVEKGKDHK-EPRKG 370
+ P P + + Q +E++ L K+++ PK E K AV + K K +P++
Sbjct: 9629 E---EPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKVLKLKPKRE 9685
Query: 371 EELEEEWTPTEK--VKCPPIGMESHRIEDNQIRASSML 406
EE + T K VK + +E+ + E I+ +++
Sbjct: 9686 EEPPAKVTEFRKRVVKEEKVSIEAPKREPQPIKEVTIM 9723
Score = 61.6 bits (148), Expect = 4e-09
Identities = 73/325 (22%), Positives = 121/325 (37%), Gaps = 72/325 (22%)
Query: 79 PGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKA 138
P E+ E+ + + PKVP+ L P P + PK + P K P+
Sbjct: 9262 PEVQKEIVTEEKIHVAISKRVEPPPKVPE--LPEKPAPEEVAPVPIPKKVEPPAPKVPEV 9319
Query: 139 TKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEG 198
KKP + K PK++P K P K+P P E + P+ P ++P
Sbjct: 9320 PKKPVPEEKKPVPVPKKEPAAPPKVPEVPKKP---VPEEKIPVPVAKKKEAPPAKVP--- 9373
Query: 199 GAPLSNNWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRP 258
E ++ E+ T I Q++ P
Sbjct: 9374 -----------------EVQKGVVTEEKIT---------------------IVTQREESP 9395
Query: 259 PPSRRRRPERVWPEPPEEKAPAPAPEERIEPPVK-PLLPPLP-PDYGDGYVIPNYDDMDY 316
PP+ P++ + PEE+ P P EE + PP K P LP P P+ +P
Sbjct: 9396 PPAVPEIPKK---KVPEERKPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVPVAKK--- 9449
Query: 317 YFGPPPPQKPDAERQTDEEKEELKKPKKEDSSPK---------EETDKWAVEKGKD---- 363
PPP+ +++ EEK + + K + P+ ++W+ + ++
Sbjct: 9450 ---APPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWSYSEEEEGVSI 9506
Query: 364 --HKEPRKGEELEEEWTPTEKVKCP 386
++E + EE E E T E ++ P
Sbjct: 9507 SVYREEEREEEEEAEVTEYEVMEEP 9531
Score = 56.6 bits (135), Expect = 1e-07
Identities = 72/267 (26%), Positives = 98/267 (36%), Gaps = 52/267 (19%)
Query: 54 VEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGS 113
+ A PP E P V A P P + PP K + KK K KV + E +
Sbjct: 8949 IRAVPPEEIPPVV----APPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMT 9004
Query: 114 PRPPKKGKEKPPKATKKPKEKP---PKATKKPKEKPPKATKK---PKEKPPKATKKPPSG 167
PR + K+ PP T P + P ++K + K T+K KEK KK
Sbjct: 9005 PR-EEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRKKEVQKEKEAVYEKKQAVH 9063
Query: 168 KRPPILAPS--------------ETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNPGEE- 212
K + S E E P P EE+ E + W+ EE
Sbjct: 9064 KEKRVFIESFEEPYDELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKKEVHEEWEEDFEEG 9123
Query: 213 -THVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWP 271
+ E E E EEE E E Y++ E I+ QK+ V+
Sbjct: 9124 QEYYEREEGYDEGEEEWE------------EAYQEREVIQVQKE-------------VYE 9158
Query: 272 EPPEEKAPAPAPEERIEPPVKPLLPPL 298
E E K PA PE++ PP K + P+
Sbjct: 9159 ESHERKVPAKVPEKKAPPPPKVIKKPV 9185
Score = 55.5 bits (132), Expect = 3e-07
Identities = 87/372 (23%), Positives = 150/372 (40%), Gaps = 45/372 (12%)
Query: 34 IEEFLEGFLSELEPEPREDDVEAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKD- 92
IE F E + ELE EP + E P EP + + K EV E +D
Sbjct: 9070 IESFEEPY-DELEVEPYTEPFEQPYYEEPDEDYEEIKVEAKK--------EVHEEWEEDF 9120
Query: 93 -KGKKG-KKDKGPKVPKESLEGSPRPPKKGK-EKPPKATKKPKEKPPKATKKPKEKPPKA 149
+G++ ++++G +E E + + + + +K ++ P K +K PPK
Sbjct: 9121 EEGQEYYEREEGYDEGEEEWEEAYQEREVIQVQKEVYEESHERKVPAKVPEKKAPPPPKV 9180
Query: 150 TKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGP-EELPQEGGAPLSNNWQN 208
KKP + + T + ++ + E + +P PS P +E E P + +
Sbjct: 9181 IKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKM 9240
Query: 209 PGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPER 268
E + H EEE + +I E+ ++ K+ PPP PE+
Sbjct: 9241 VISEEKMFFASH---TEEEVSVTVPEVQKEIVTEEK---IHVAISKRVEPPPKVPELPEK 9294
Query: 269 VWPEPPEEKAPAPAPEERIEPPVKPLLPPLP----PDYGDGYVIPNYDDMDYYFGPPPPQ 324
PEE AP P P +++EPP P +P +P P+ +P + PP+
Sbjct: 9295 ---PAPEEVAPVPIP-KKVEPPA-PKVPEVPKKPVPEEKKPVPVPKKEP------AAPPK 9343
Query: 325 KPDA-ERQTDEEKEELKKPKKEDSSPKE--ETDKWAVEKGK-------DHKEPRKGEELE 374
P+ ++ EEK + KK+++ P + E K V + K + P E+
Sbjct: 9344 VPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIP 9403
Query: 375 EEWTPTEKVKCP 386
++ P E+ P
Sbjct: 9404 KKKVPEERKPVP 9415
Score = 44.3 bits (103), Expect = 7e-04
Identities = 49/178 (27%), Positives = 71/178 (39%), Gaps = 38/178 (21%)
Query: 35 EEFLEGFLSELEPEPREDDV----------EAPPPPEPTP--RVRKAQAGGKPGKRPGTA 82
E+ + L E +PEP+E+ V E P EP +V+K P +P
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEE 10988
Query: 83 AEVPPEKTKDKGKKGKKDKGPKV----PKESLEGSPRPPKKGKE-KPPKATKKP------ 131
EVP TK + K + K P++ P + E P+P + K KPP +P
Sbjct: 10989 VEVPTV-TKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPIAAP 11047
Query: 132 -------KEKPPKATKKPKEKP-------PKATKKPKEKPPKATKKPPSGKRPPILAP 175
K+ KA K+ KP PK T P E + + G++PP AP
Sbjct: 11048 VTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAP 11105
Score = 41.6 bits (96), Expect = 0.004
Identities = 52/234 (22%), Positives = 93/234 (39%), Gaps = 27/234 (11%)
Query: 145 KPPKATKKPKEKPPKATKKPPSGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAPLSN 204
KPP P + P + PP++AP L P P P P+ + A
Sbjct: 8933 KPPDIPDSRVPIPTMPIRAVPPEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKK- 8991
Query: 205 NWQNPGEETHVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRR 264
+ V A+ + P EE + I + E + + ++ + R+
Sbjct: 8992 ------DAKKVVAKPKEMTPREEIVKKPPPPTTLIPAKAPEIIDVSSKAEEVKIMTITRK 9045
Query: 265 RPERVWPEPPEEKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPPPQ 324
+ + E EK A E+R+ + + + P YD+++ P +
Sbjct: 9046 KEVQKEKEAVYEKKQAVHKEKRV--------------FIESFEEP-YDELEVEPYTEPFE 9090
Query: 325 KPDAERQTDEEKEELKKPKKEDSSPKEETDKWAVEKGKDHKEPRKG-EELEEEW 377
+P E + DE+ EE+K K++ + E D E+G+++ E +G +E EEEW
Sbjct: 9091 QPYYE-EPDEDYEEIKVEAKKEVHEEWEED---FEEGQEYYEREEGYDEGEEEW 9140
Score = 34.7 bits (78), Expect = 0.54
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 3/70 (4%)
Query: 115 RPPKKGKEKPPKA-TKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGK--RPP 171
R +K PP+ + +P+ K P+A K PK PK P TK P+ K P
Sbjct: 32654 RVTEKAVTSPPRVKSPEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLP 32713
Query: 172 ILAPSETLEW 181
+ AP + ++
Sbjct: 32714 VSAPPKITQF 32723
Score = 34.3 bits (77), Expect = 0.71
Identities = 23/56 (41%), Positives = 26/56 (46%), Gaps = 7/56 (12%)
Query: 113 SPRPPKKGKE--KPPKATKKPKEKPPKATKKPKEKPPKATKK----PKEKPPKATK 162
SP P K E K PK K P+ PKA P E P T+K P PPK T+
Sbjct: 32668 SPEPRVKSPEAVKSPKRVKSPEPSHPKAV-SPTETKPTPTEKVQHLPVSAPPKITQ 32722
Score = 33.9 bits (76), Expect = 0.92
Identities = 36/140 (25%), Positives = 55/140 (39%), Gaps = 18/140 (12%)
Query: 61 EPTPRV---RKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGP-KVPKESLEGSPRP 116
EP P V RK Q + T + + T + D+G V E+ EG
Sbjct: 32587 EPVPTVTWLRKGQVLSTSARHQVTTTKY--KSTFEISSVQASDEGNYSVVVENSEGKQEA 32644
Query: 117 PKKGKEKPPKATKKPKEKPPKA-TKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPILAP 175
+ + T+K PP+ + +P+ K P+A K PK K P P ++P
Sbjct: 32645 EFTLTIQKARVTEKAVTSPPRVKSPEPRVKSPEAVKSPKR------VKSPEPSHPKAVSP 32698
Query: 176 SETLEWPLPPPPSPGPEELP 195
+ET P P+ + LP
Sbjct: 32699 TET-----KPTPTEKVQHLP 32713
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 90.1 bits (222), Expect = 1e-17
Identities = 78/281 (27%), Positives = 104/281 (37%), Gaps = 40/281 (14%)
Query: 55 EAPPPPEPTPRVRKAQAGGKPGKRPGTAAEVPPEKTKDKGKKGKKDKGPKVPKESLEGSP 114
+ PPPP P+ Q G KP P PP K + +G K + P+ P +G P
Sbjct: 69 QGPPPPPGKPQGPPPQGGNKPQGPP------PPGKPQGPPPQGDKSRSPRSPPGKPQGPP 122
Query: 115 RPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGKRPPIL- 173
+ PP KP+ PP+ KP+ PP KP+ PP+ K S + PP
Sbjct: 123 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGDNKSRSSRSPPGKP 180
Query: 174 --APSETLEWPLPPPPSPG-PEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEETEQ 230
P + P PPP PG P+ P +GG N Q P P + +
Sbjct: 181 QGPPPQGGNQPQGPPPPPGKPQGPPPQGG----NKPQGP-----------PPPGKPQGPP 225
Query: 231 PTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPAPEERIEPP 290
P D Q R K PPP +P+ P P + + P P + + P
Sbjct: 226 PQGDNKSQSARSP--------PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGP 277
Query: 291 VKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPP-----PQKP 326
P P PP G + GPPP PQ P
Sbjct: 278 PPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP 318
Score = 78.2 bits (191), Expect = 4e-14
Identities = 79/303 (26%), Positives = 110/303 (36%), Gaps = 58/303 (19%)
Query: 55 EAPPPPEPTPRVRKAQAGGKP-GKRPGTAAEVPPEKTKDKGKKGKKDKG-----PKVPKE 108
+ PPPP P+ Q G KP G P + PP + +K + + G P
Sbjct: 130 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGN 189
Query: 109 SLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGK 168
+G P PP K + PP+ KP+ PP KP+ PP+ K ++ + PP
Sbjct: 190 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGDNK-----SQSARSPPGKP 242
Query: 169 RPPILAPSETLEWPLPPPPSPG-PEELPQEG-----GAPLSNNWQNPGEETHVEAREHQP 222
+ P P + P PPP PG P+ P +G G P Q P + ++R +
Sbjct: 243 QGP---PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299
Query: 223 EPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRP-----ERVWPEPPEEK 277
P + P N + + P PPP + + P + PP K
Sbjct: 300 PPGKPQGPPPQGGN---------------QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK 344
Query: 278 APAPAPE------ERIEPPVKPLLPPL---------PPDYGDGYVIPNYDDMDYYFGPP- 321
P P+ PP KP PP PP G P GPP
Sbjct: 345 PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 404
Query: 322 PPQ 324
PPQ
Sbjct: 405 PPQ 407
Score = 71.2 bits (173), Expect = 5e-12
Identities = 69/260 (26%), Positives = 101/260 (38%), Gaps = 53/260 (20%)
Query: 55 EAPPPPEPTPRVRKAQAGGKP-GKRPGTAAEVPPEKTKDKGKKGKKDKG-----PKVPKE 108
+ PPPP P+ Q G KP G P + PP + +K + + G P
Sbjct: 192 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 109 SLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPPSGK 168
+G P PP K + PP+ KP+ PP KP+ PP+ K ++++ PP
Sbjct: 252 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGGSK-----SRSSRSPPGKP 304
Query: 169 RPPILAPSETLEWPLPPPPSPG-PEELPQEGGAPLSNNWQNPGEETHVEAREHQPEPEEE 227
+ P P + P PPP PG P+ P +GG N Q P P P +
Sbjct: 305 QGP---PPQGGNQPQGPPPPPGKPQGPPPQGG----NKPQGP------------PPPGKP 345
Query: 228 TEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWPEPPEEKAPAPA---PE 284
P + + + R PP + + P + P + P PA P+
Sbjct: 346 QGPPPQGGS---------------KSRSARSPPGKPQGPPQQEGNNP-QGPPPPAGGNPQ 389
Query: 285 ERIEPPV-KPLLPPLPPDYG 303
+ PP +P PP PP G
Sbjct: 390 QPQAPPAGQPQGPPRPPQGG 409
Score = 70.9 bits (172), Expect = 7e-12
Identities = 66/238 (27%), Positives = 86/238 (36%), Gaps = 33/238 (13%)
Query: 97 GKKDKGPKVPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEK 156
G K +GP P +G P + PP KP+ PP+ KP+ PP KP+
Sbjct: 44 GNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGP 101
Query: 157 PPKATKK--PPSGKRPPILAPSETLEWPLPPPPSPG-PEELPQEGGAPLSNNWQNPGEET 213
PP+ K P S P P + P PPP PG P+ P +GG N Q P
Sbjct: 102 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG----NKPQGP---- 153
Query: 214 HVEAREHQPEPEEETEQPTLDYNDQIEREDYEDFEYIRRQKQPRPPPSRRRRPERVWPEP 273
P + + P D + R K PPP +P+ P P
Sbjct: 154 -------PPPGKPQGPPPQGDNKSRSSRSP--------PGKPQGPPPQGGNQPQGPPPPP 198
Query: 274 PEEKAPAPAPEERIEPPVKPLLPPLPPDYGDGYVIPNYDDMDYYFGPPP-----PQKP 326
+ + P P + + P P P PP GD GPPP PQ P
Sbjct: 199 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP 256
Score = 63.5 bits (153), Expect = 1e-09
Identities = 46/160 (28%), Positives = 64/160 (40%), Gaps = 15/160 (9%)
Query: 55 EAPPPPEPTPRVRKAQAGGKP-GKRPGTAAEVPPEKTKDKGKKGKKDKG-----PKVPKE 108
+ PPPP P+ Q G KP G P + PP + K + + G P
Sbjct: 254 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313
Query: 109 SLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPK--EKPPKATKKPP- 165
+G P PP K + PP+ KP+ PP KP+ PP+ K + PP + PP
Sbjct: 314 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGGSKSRSARSPPGKPQGPPQ 371
Query: 166 ----SGKRPPILAPSETLEWPLPPPPSPGPEELPQEGGAP 201
+ + PP A + PP P P +GG P
Sbjct: 372 QEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 411
Score = 63.2 bits (152), Expect = 1e-09
Identities = 50/168 (29%), Positives = 68/168 (40%), Gaps = 15/168 (8%)
Query: 47 PEPREDDVEAPPPPEP-TPRVRKAQAGGKP-GKRPGTAAEVPPEKTKDKGKKGKKDKGPK 104
P P+ + PPP P P+ Q G KP G P + PP + G K + +
Sbjct: 245 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP------QGGSKSRSSR 298
Query: 105 VPKESLEGSPRPPKKGKEKPPKATKKPKEKPPKATKKPKEKPPKATKKPKEKPPKATKKP 164
P +G P + PP KP+ PP+ KP+ PP KP+ PP+ K
Sbjct: 299 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG--KPQGPPPQGGSKS 356
Query: 165 PSGKRPPIL---APSETLEWPLPPPPSPGPEELPQEGGAPLSNNWQNP 209
S + PP P + P PPP G PQ+ AP + Q P
Sbjct: 357 RSARSPPGKPQGPPQQEGNNPQGPPPPAGGN--PQQPQAPPAGQPQGP 402
>gi|62420886 discoidin domain receptor family, member 2 precursor
[Homo sapiens]
Length = 855
Score = 88.2 bits (217), Expect = 4e-17
Identities = 52/160 (32%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Query: 387 PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWC----AEDDARTQ 442
P+GM +I D I ASS A+ GRL+ + G DGAWC E D +
Sbjct: 33 PLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEG-------DGAWCPEIPVEPDDLKE 85
Query: 443 WIEVDTRRTTRFTGVITQGRDSSIHD-DFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNV 501
++++D T V TQGR + H +F + + +S D W+ + N + + GN
Sbjct: 86 FLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNS 145
Query: 502 DKDTPVLSELPEPVVARFIRIYPLTWNG-SLCMRLEVLGC 540
+ L +L P+VARF+R P+T + ++CMR+E+ GC
Sbjct: 146 NPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGC 185
>gi|62420884 discoidin domain receptor family, member 2 precursor
[Homo sapiens]
Length = 855
Score = 88.2 bits (217), Expect = 4e-17
Identities = 52/160 (32%), Positives = 81/160 (50%), Gaps = 13/160 (8%)
Query: 387 PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWC----AEDDARTQ 442
P+GM +I D I ASS A+ GRL+ + G DGAWC E D +
Sbjct: 33 PLGMSGGQIPDEDITASSQWSESTAAKYGRLDSEEG-------DGAWCPEIPVEPDDLKE 85
Query: 443 WIEVDTRRTTRFTGVITQGRDSSIHD-DFVTTFFVGFSNDSQTWVMYTNGYEEMTFHGNV 501
++++D T V TQGR + H +F + + +S D W+ + N + + GN
Sbjct: 86 FLQIDLHTLHFITLVGTQGRHAGGHGIEFAPMYKINYSRDGTRWISWRNRHGKQVLDGNS 145
Query: 502 DKDTPVLSELPEPVVARFIRIYPLTWNG-SLCMRLEVLGC 540
+ L +L P+VARF+R P+T + ++CMR+E+ GC
Sbjct: 146 NPYDIFLKDLEPPIVARFVRFIPVTDHSMNVCMRVELYGC 185
>gi|167830475 milk fat globule-EGF factor 8 protein isoform a [Homo
sapiens]
Length = 387
Score = 87.4 bits (215), Expect = 7e-17
Identities = 50/156 (32%), Positives = 77/156 (49%), Gaps = 3/156 (1%)
Query: 387 PIGMESHRIEDNQIRASSMLRHGLGAQRGRLNMQTGATEDDYYDGAWCAEDDARTQWIEV 446
P+G++++ I D QI ASS + G N + AW A QW++V
Sbjct: 233 PLGLKNNSIPDKQITASSSYKTW-GLHLFSWNPSYARLDKQGNFNAWVAGSYGNDQWLQV 291
Query: 447 DTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFSNDSQTWVMYTNGY--EEMTFHGNVDKD 504
D + TG+ITQG + FV ++ V +SNDS W Y + F GN D
Sbjct: 292 DLGSSKEVTGIITQGARNFGSVQFVASYKVAYSNDSANWTEYQDPRTGSSKIFPGNWDNH 351
Query: 505 TPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGC 540
+ + P++AR++RI P+ W+ + +RLE+LGC
Sbjct: 352 SHKKNLFETPILARYVRILPVAWHNRIALRLELLGC 387
Score = 68.6 bits (166), Expect = 3e-11
Identities = 49/168 (29%), Positives = 83/168 (49%), Gaps = 14/168 (8%)
Query: 382 KVKC-PPIGMESHRIEDNQIRASSMLRHGLGAQR-----GRLNMQTGATEDDYYDGAWCA 435
+ KC P+G+E+ I ++QI ASS+ LG Q RLN + G AW
Sbjct: 67 ETKCVEPLGLENGNIANSQIAASSVRVTFLGLQHWVPELARLN-RAGMVN------AWTP 119
Query: 436 EDDARTQWIEVDTRRTTRFTGVITQGRDSSIHDDFVTTFFVGFS-NDSQTWVMYTNGYEE 494
+ WI+V+ R TGV+TQG +++ F V +S N + ++ +
Sbjct: 120 SSNDDNPWIQVNLLRRMWVTGVVTQGASRLASHEYLKAFKVAYSLNGHEFDFIHDVNKKH 179
Query: 495 MTFHGNVDKDTPVLSELPEPVVARFIRIYPLTWNGSLCMRLEVLGCSV 542
F GN +K+ ++ PV A+++R+YP + + + +R E+LGC +
Sbjct: 180 KEFVGNWNKNAVHVNLFETPVEAQYVRLYPTSCHTACTLRFELLGCEL 227
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.134 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,840,612
Number of Sequences: 37866
Number of extensions: 3859784
Number of successful extensions: 56128
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 511
Number of HSP's successfully gapped in prelim test: 1700
Number of HSP's that attempted gapping in prelim test: 25125
Number of HSP's gapped (non-prelim): 18763
length of query: 1158
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1045
effective length of database: 13,968,660
effective search space: 14597249700
effective search space used: 14597249700
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.