Guide to the Human Genome
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Search of human proteins with 52627149

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52627149 telomeric repeat binding factor 2, interacting
protein [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52627149 telomeric repeat binding factor 2, interacting prote...   793   0.0  
gi|17975763 myelin transcription factor 1 [Homo sapiens]               47   4e-05
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    45   1e-04
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    45   1e-04
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ...    45   1e-04
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ...    45   1e-04
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)...    45   2e-04
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    44   3e-04
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           43   6e-04
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           43   6e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     42   7e-04
gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo sapi...    42   0.001
gi|30795188 Williams Beuren syndrome chromosome region 19 protei...    42   0.001
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         42   0.001
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    42   0.001
gi|194595492 speedy homolog E5 [Homo sapiens]                          42   0.001
gi|226246595 speedy homolog E6 [Homo sapiens]                          41   0.002
gi|239743297 PREDICTED: speedy homolog E6 [Homo sapiens]               41   0.002
gi|239508980 PREDICTED: speedy homolog E6 (Xenopus laevis) [Homo...    41   0.002
gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 famil...    41   0.002
gi|55956788 nucleolin [Homo sapiens]                                   41   0.002
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    41   0.002
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa...    41   0.002
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    40   0.003
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    40   0.003
gi|195976782 Paf1/RNA polymerase II complex component [Homo sapi...    40   0.003
gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]         40   0.003
gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]     40   0.004
gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]     40   0.004
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ...    40   0.005

>gi|52627149 telomeric repeat binding factor 2, interacting protein
           [Homo sapiens]
          Length = 399

 Score =  793 bits (2048), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MAEAMDLGKDPNGPTHSSTLFVRDDGSSMSFYVRPSPAKRRLSTLILHGGGTVCRVQEPG 60
           MAEAMDLGKDPNGPTHSSTLFVRDDGSSMSFYVRPSPAKRRLSTLILHGGGTVCRVQEPG
Sbjct: 1   MAEAMDLGKDPNGPTHSSTLFVRDDGSSMSFYVRPSPAKRRLSTLILHGGGTVCRVQEPG 60

Query: 61  AVLLAQPGEALAEASGDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGALAE 120
           AVLLAQPGEALAEASGDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGALAE
Sbjct: 61  AVLLAQPGEALAEASGDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGALAE 120

Query: 121 GAAEPEPQRHAGRIAFTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQSL 180
           GAAEPEPQRHAGRIAFTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQSL
Sbjct: 121 GAAEPEPQRHAGRIAFTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQSL 180

Query: 181 KDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVK 240
           KDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVK
Sbjct: 181 KDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVK 240

Query: 241 EEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEE 300
           EEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEE
Sbjct: 241 EEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEE 300

Query: 301 EEEEKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGYP 360
           EEEEKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGYP
Sbjct: 301 EEEEKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGYP 360

Query: 361 IWSRQDDIDLQKDDEDTREALVKKFGAQNVARRIEFRKK 399
           IWSRQDDIDLQKDDEDTREALVKKFGAQNVARRIEFRKK
Sbjct: 361 IWSRQDDIDLQKDDEDTREALVKKFGAQNVARRIEFRKK 399


>gi|17975763 myelin transcription factor 1 [Homo sapiens]
          Length = 1121

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 55/262 (20%), Positives = 103/262 (39%), Gaps = 46/262 (17%)

Query: 68  GEALAEASGDFISTQYILDCVERNERLELEAYRLGPASAADTGSEAKPGA--------LA 119
           G A A + G + S Q I+        L L           D G  AKPG          A
Sbjct: 147 GSATASSKGSYSSYQGII----ATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAA 202

Query: 120 EGAAEPEPQRHAGRIAFTDADDVAILTYVKENARSPSSVTGNALWKAMEKSSLTQHSWQS 179
           EGAA  E ++    I   DA++V  +T  +     P S+   A  ++ ++  +  H  + 
Sbjct: 203 EGAASEEGEKGLF-IQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEED 261

Query: 180 LKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYV 239
            ++                        ++ + + EED E  +  E + +   +  EEE  
Sbjct: 262 EEE------------------------EEEEEEEEEDEEEEEEEEEEEEEEEEEEEEEEE 297

Query: 240 KEEIQENEEAVKKMLVE------ATREFEEVVVDESP---PDFEIHITMCDDDPPTPEED 290
           +EE +E EEA   ++ +      + ++  E+   ESP   P++ + + +  DD    +  
Sbjct: 298 EEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSVIVEVRSDDDKDEDTH 357

Query: 291 SETQPDEEEEEEEEKVSQPEVG 312
           S      +E E ++ +++  +G
Sbjct: 358 SRKSTVTDESEMQDMMTRGNLG 379


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 54/210 (25%), Positives = 92/210 (43%), Gaps = 28/210 (13%)

Query: 149  KENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQK 208
            K+N  +P    G+   K    S     S +S K RY   L    HK  + D   S   +K
Sbjct: 1267 KQNEENP----GDEEAKNQVNSESDSDSEESKKPRYRHRLL--RHKLTVSDGE-SGEEKK 1319

Query: 209  LKRKAEEDPEAADSGEPQNKRTPDLP-EEEYVKEEIQENEE--------AVKKMLVEATR 259
             K K  ++ +  +  +  ++ + D   +E  V EE+ E+E+        A K  L E  R
Sbjct: 1320 TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQR 1379

Query: 260  EFEEV-------VVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVG 312
             +++        V ++S  + + +    +++    EE+ E + +EEEEEE+E       G
Sbjct: 1380 SYKQKKKRRRIKVQEDSSSENKSN---SEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1436

Query: 313  AAIKIIRQLMEKFNLDLSTVTQAFLKNSGE 342
               K IR++++  +  L T TQ  LK   E
Sbjct: 1437 KGRKKIRKILK--DDKLRTETQNALKEEEE 1464


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 54/210 (25%), Positives = 92/210 (43%), Gaps = 28/210 (13%)

Query: 149  KENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQK 208
            K+N  +P    G+   K    S     S +S K RY   L    HK  + D   S   +K
Sbjct: 1305 KQNEENP----GDEEAKNQVNSESDSDSEESKKPRYRHRLL--RHKLTVSDGE-SGEEKK 1357

Query: 209  LKRKAEEDPEAADSGEPQNKRTPDLP-EEEYVKEEIQENEE--------AVKKMLVEATR 259
             K K  ++ +  +  +  ++ + D   +E  V EE+ E+E+        A K  L E  R
Sbjct: 1358 TKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQR 1417

Query: 260  EFEEV-------VVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVG 312
             +++        V ++S  + + +    +++    EE+ E + +EEEEEE+E       G
Sbjct: 1418 SYKQKKKRRRIKVQEDSSSENKSN---SEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1474

Query: 313  AAIKIIRQLMEKFNLDLSTVTQAFLKNSGE 342
               K IR++++  +  L T TQ  LK   E
Sbjct: 1475 KGRKKIRKILK--DDKLRTETQNALKEEEE 1502


>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
           sapiens]
          Length = 788

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 48/207 (23%), Positives = 81/207 (39%), Gaps = 13/207 (6%)

Query: 150 ENARSPSSVTGNAL---------WKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDA 200
           E AR  + V GNAL          +  E  SL +++  ++ +   + LR Q +  +    
Sbjct: 97  ELARMENGVLGNALEGVHVEEEEGEKTEDESLVENN-DNIDEEAREELREQVYDAMGEKE 155

Query: 201 PVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATRE 260
               +  K   K E D E     E   +   D+ +     EE QE  +     L E + E
Sbjct: 156 EAKKTEDKSLAKPETDKEQDSEMEKGGREDMDISKSA---EEPQEKVDLTLDWLTETSEE 212

Query: 261 FEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQ 320
            +     E P + E+     + + P  EE+      + +EE  EK  Q + G  I  I +
Sbjct: 213 AKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEE 272

Query: 321 LMEKFNLDLSTVTQAFLKNSGELEATS 347
             ++ + +   VT      + E+EA S
Sbjct: 273 KPKEVSEEQPVVTLEKQGTAVEVEAES 299



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 25/117 (21%), Positives = 51/117 (43%), Gaps = 13/117 (11%)

Query: 196 LLGD-APVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKML 254
           ++GD  P+ P +   +    +D     SG  +  R   +P +E  K  ++E+E A   + 
Sbjct: 385 VVGDQTPIEPQTSIERLTETKD----GSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVD 440

Query: 255 VEATREFEEVVVDESPPDFEIHITMCDDDPPTPE---EDSETQPDEEEEEEEEKVSQ 308
            +  +        E  P+ ++ I   ++     E   E  ET+  EE+++E +K  +
Sbjct: 441 TKVAQG-----ATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEE 492


>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
           sapiens]
          Length = 790

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 48/207 (23%), Positives = 81/207 (39%), Gaps = 13/207 (6%)

Query: 150 ENARSPSSVTGNAL---------WKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDA 200
           E AR  + V GNAL          +  E  SL +++  ++ +   + LR Q +  +    
Sbjct: 99  ELARMENGVLGNALEGVHVEEEEGEKTEDESLVENN-DNIDEEAREELREQVYDAMGEKE 157

Query: 201 PVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATRE 260
               +  K   K E D E     E   +   D+ +     EE QE  +     L E + E
Sbjct: 158 EAKKTEDKSLAKPETDKEQDSEMEKGGREDMDISKSA---EEPQEKVDLTLDWLTETSEE 214

Query: 261 FEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQ 320
            +     E P + E+     + + P  EE+      + +EE  EK  Q + G  I  I +
Sbjct: 215 AKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSVSGTDVQEECREKGGQEKQGEVIVSIEE 274

Query: 321 LMEKFNLDLSTVTQAFLKNSGELEATS 347
             ++ + +   VT      + E+EA S
Sbjct: 275 KPKEVSEEQPVVTLEKQGTAVEVEAES 301



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 25/117 (21%), Positives = 51/117 (43%), Gaps = 13/117 (11%)

Query: 196 LLGD-APVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKML 254
           ++GD  P+ P +   +    +D     SG  +  R   +P +E  K  ++E+E A   + 
Sbjct: 387 VVGDQTPIEPQTSIERLTETKD----GSGLEEKVRAKLVPSQEETKLSVEESEAAGDGVD 442

Query: 255 VEATREFEEVVVDESPPDFEIHITMCDDDPPTPE---EDSETQPDEEEEEEEEKVSQ 308
            +  +        E  P+ ++ I   ++     E   E  ET+  EE+++E +K  +
Sbjct: 443 TKVAQG-----ATEKSPEDKVQIAANEETQEREEQMKEGEETEGSEEDDKENDKTEE 494


>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
            [Homo sapiens]
          Length = 2073

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 22/170 (12%)

Query: 148  VKENAR-SPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSS 206
            +KE ++ +P  +    +W    K  L++  W+  K+R       + + Y   + P+ P  
Sbjct: 1231 LKEGSKDNPEPLKCKQVWPKGTKRGLSK--WRQNKERKTGF---KLNLYTPPETPMEPDE 1285

Query: 207  QKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVV 266
            Q    + +E  E   S  P             ++EE++E  EA   +L +     EE   
Sbjct: 1286 QVTVEEQKETSEGKTSPSPIR-----------IEEEVKETGEA---LLPQEENRREETCA 1331

Query: 267  DESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIK 316
              SP          +DD   PEE+ E + +EEEEEEEE+  + E G  ++
Sbjct: 1332 PVSPNTSPGEKP--EDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVE 1379



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 38/162 (23%), Positives = 66/162 (40%), Gaps = 20/162 (12%)

Query: 204  PSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEE 263
            PS  +     +ED    +S E + +   +LP E +  +E+ EN+E    + V+      E
Sbjct: 1418 PSHNEDHDADDEDDSHMESAEVEKE---ELPRESF--KEVLENQETFLDLNVQPGHSNPE 1472

Query: 264  VVVD---------ESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAA 314
            V++D          S P       +  D    PE D E  P E+ +++++K S+ EV   
Sbjct: 1473 VLMDCGVDLTASCNSEPK-----ELAGDPEAVPESDEEPPPGEQAQKQDQKNSK-EVDTE 1526

Query: 315  IKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRA 356
             K       + + +     Q+  + S E + T    A  Q A
Sbjct: 1527 FKEGNPATMEIDSETVQAVQSLTQESSEQDDTFQDCAETQEA 1568



 Score = 36.2 bits (82), Expect = 0.054
 Identities = 33/101 (32%), Positives = 44/101 (43%), Gaps = 7/101 (6%)

Query: 207  QKLKRKAEEDPEAADSGEPQNKRTPDL--PEEEYVKEEIQENEEAVKKMLVEATREFEEV 264
            Q+  R+ E     + +  P  K   DL  PEEE  +EE +E EE       E   E E  
Sbjct: 1321 QEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEE-----EEGEEEEGG 1375

Query: 265  VVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEK 305
               E  PD        + +  T +EDS    D EEEEEE++
Sbjct: 1376 GNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDE 1416



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 31/127 (24%), Positives = 55/127 (43%), Gaps = 25/127 (19%)

Query: 196  LLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKR-------TPDLPEEEYVKEEIQENEE 248
            L+ +A VS   ++ +++AE   E A   E + +        +   P +   K +   + E
Sbjct: 991  LISNAAVSEEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPE 1050

Query: 249  A-----VKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEE 303
            +      +  L+E ++E  E   +E             +D    EE+ E + DEEEEEEE
Sbjct: 1051 SRPVTGERGQLLELSKESSEEEEEE-------------EDEEEEEEEEEEEEDEEEEEEE 1097

Query: 304  EKVSQPE 310
            E+  + E
Sbjct: 1098 EEEEEEE 1104



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 32/115 (27%), Positives = 49/115 (42%), Gaps = 14/115 (12%)

Query: 200  APVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEA-- 257
            APVSP++        E PE  D  +P+ +   +  EEE  +EE  E EE    +  +   
Sbjct: 1331 APVSPNTSP-----GEKPED-DLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDG 1384

Query: 258  --TREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
              ++E EE  +     D        DD     EED E   +E+ + ++E  S  E
Sbjct: 1385 AKSQEKEEPEISTEKEDS----ARLDDHEEEEEEDEEPSHNEDHDADDEDDSHME 1435



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 14/42 (33%), Positives = 23/42 (54%)

Query: 210  KRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVK 251
            K  +EE+ E  D  E + +   +  EEE  +EE +E EE ++
Sbjct: 1066 KESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQ 1107


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 35/146 (23%), Positives = 66/146 (45%), Gaps = 12/146 (8%)

Query: 163 LWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADS 222
           +W+  EK    +  W+  K +       QE K    +  +    +K+ R+ E+  E  + 
Sbjct: 546 MWREEEKMHEQEKIWEEEKRQE------QEDKMWRQEEKIREQEEKVWRQEEKIREQEEK 599

Query: 223 GEPQNKRTPDLPEEEYVKEE---IQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITM 279
            + Q ++     +EE ++E+   IQE EE +++   E  RE EE+  ++     E    M
Sbjct: 600 RQEQEEKM--WKQEEKIREQEEKIQEQEEKIREQ-EEKIREQEEMTQEQEEKMGEQEEKM 656

Query: 280 CDDDPPTPEEDSETQPDEEEEEEEEK 305
           C+ +    E++      EE+  E+EK
Sbjct: 657 CEQEEKMQEQEETMWRQEEKIREQEK 682



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 34/153 (22%), Positives = 72/153 (47%), Gaps = 12/153 (7%)

Query: 163 LWKAMEKSSLTQHSWQSLKDRYLKH---LRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEA 219
           +W+  EK    +   Q  +++  K    +R QE K    +  +    +K++ + E   E 
Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ 645

Query: 220 ADS-GEPQNK---RTPDLPEEEYV----KEEIQENEEAVKKMLVEATREFEEVVVDESPP 271
            +  GE + K   +   + E+E      +E+I+E E+ +++   E  RE EE++ ++   
Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKIREQ-EEKIREQEEMMQEQEEK 704

Query: 272 DFEIHITMCDDDPPTPEEDSETQPDEEEEEEEE 304
            +E    MC+ +    E++ + +  EE+  E+E
Sbjct: 705 MWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQE 737



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 34/161 (21%), Positives = 65/161 (40%), Gaps = 16/161 (9%)

Query: 151 NARSPSSVTGNALWKAMEKSSLTQHSWQSLK-DRYLKHLRGQEHKYLLGDAPVSPSSQKL 209
           +A+  + V  N LW  + +    +   Q  K   + + ++ QE K    +  +    +K+
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337

Query: 210 KRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDES 269
           +R+ E   E  +    Q        E  + KEE    +E +     E  R  EE++ ++ 
Sbjct: 338 RRQEEMMWEKEEKMRRQE-------EMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 390

Query: 270 PPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
               E+   M         E  + +  EE+ +EEEK+ + E
Sbjct: 391 EKIRELEEKM--------HEQEKIREQEEKRQEEEKIREQE 423



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 30/151 (19%), Positives = 66/151 (43%), Gaps = 16/151 (10%)

Query: 163 LWKAMEKSSLTQHS-WQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAAD 221
           +W+  EK    +   W+  K+  ++ L  + H+            ++ + K +E+ +  +
Sbjct: 372 MWEKEEKMRRQEEMMWE--KEEKIRELEEKMHE--------QEKIREQEEKRQEEEKIRE 421

Query: 222 SGEPQNKRTPDLPEEEYVKEEIQENEEAVKKM--LVEATREFEEVVVDESPPDFEIHITM 279
             + Q +      +EE ++E+ ++  E  KKM    E   E E++  +E   + E    M
Sbjct: 422 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQE---EM 478

Query: 280 CDDDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
              +    E++   +  E+  E+EEK+ + E
Sbjct: 479 WRQEEKIHEQEEIWRQKEKMHEQEEKIRKQE 509


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 47/174 (27%), Positives = 68/174 (39%), Gaps = 36/174 (20%)

Query: 190 GQEHKYLLGDAPVSPSSQKLKRKAEE-----DPEAADSGEPQNKRTPDLPEEEYVKEEIQ 244
           G E   L  D   S SSQ  K +        D E   SG    +      EEE V+E+++
Sbjct: 151 GSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVE 210

Query: 245 ENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEE 304
           E+EE                 V+E            ++D    E+  E + +EEEEEEEE
Sbjct: 211 EDEE-----------------VEED----------AEEDEEVDEDGEEEEEEEEEEEEEE 243

Query: 305 KVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADG 358
           +  + E     +  R   E+ N D  T ++A    S  +  T   + SG   DG
Sbjct: 244 EEEEEEYE---QDERDQKEEGN-DYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 47/174 (27%), Positives = 68/174 (39%), Gaps = 36/174 (20%)

Query: 190 GQEHKYLLGDAPVSPSSQKLKRKAEE-----DPEAADSGEPQNKRTPDLPEEEYVKEEIQ 244
           G E   L  D   S SSQ  K +        D E   SG    +      EEE V+E+++
Sbjct: 151 GSERIGLEVDRRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQGNNTENEEEGVEEDVE 210

Query: 245 ENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEE 304
           E+EE                 V+E            ++D    E+  E + +EEEEEEEE
Sbjct: 211 EDEE-----------------VEED----------AEEDEEVDEDGEEEEEEEEEEEEEE 243

Query: 305 KVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADG 358
           +  + E     +  R   E+ N D  T ++A    S  +  T   + SG   DG
Sbjct: 244 EEEEEEYE---QDERDQKEEGN-DYDTRSEASDSGSESVSFTDGSVRSGSGTDG 293


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 44/188 (23%), Positives = 80/188 (42%), Gaps = 31/188 (16%)

Query: 148 VKENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQ 207
           VKE A+SP         K+ EK+          K    +  R    K+   +   SP  +
Sbjct: 740 VKEEAKSPEKA------KSPEKAKTLDVKSPEAKTPAKEEARSPADKF--PEKAKSPVKE 791

Query: 208 KLKRKAEEDPEAADSGEPQNKRTPD--LPEEEYVKEEIQENEEAVKKMLVEATREFEEVV 265
           ++K      PE A S   ++ + P+  +P++E VK  ++E E+  +  + E  ++ EE  
Sbjct: 792 EVK-----SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEK 846

Query: 266 VDESPPDFEIHITMCDDDP----PTPEEDSETQP------------DEEEEEEEEKVSQP 309
              +P   E   +  ++ P    P P+ + + +P             +EE E+++KV  P
Sbjct: 847 APATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTP 906

Query: 310 EVGAAIKI 317
           E  A  K+
Sbjct: 907 EKEAPAKV 914



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 49/216 (22%), Positives = 88/216 (40%), Gaps = 14/216 (6%)

Query: 107 ADTGSEAKPGALAEGAAEPEPQRHAGRIAFTDADDVAILTYVKENARSPSSVTGNALWKA 166
           A T  +AK   + E A  PE  +   +    D       T  KE ARSP+          
Sbjct: 730 AKTPEKAK-SPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP 788

Query: 167 MEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVS----PSSQKLK---RKAEED--P 217
           +++   +    +S      K    +  K     +PV     P   K+K   +KAEE+  P
Sbjct: 789 VKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAP 848

Query: 218 EAADSGEPQNKRTPDLPEEEYVKEEIQENEEAV----KKMLVEATREFEEVVVDESPPDF 273
               + E ++ +  + P++E  K +++E +E      K+  VEA +E  E       P+ 
Sbjct: 849 ATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEK 908

Query: 274 EIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQP 309
           E    +   +   P+E +E    E ++ + ++ S+P
Sbjct: 909 EAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKP 944



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 29/121 (23%), Positives = 58/121 (47%), Gaps = 11/121 (9%)

Query: 200 APVSPSSQKLKRKAEEDPEAADSGEP--QNKRTP--DLPEEEYVKEEIQENEEAVKKMLV 255
           AP +P +++ K   +E+    ++ +P  + K+ P  + P+E  V+ + +E E+  K    
Sbjct: 847 APATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTP 906

Query: 256 EATREFEEVVVDESPPDFEIHITMCDDD------PPTPEEDSETQPDEEEEEEEEKVSQP 309
           E     +  V +++ P  +  +   + D      P  P E  E  P E+++ +EEK  +P
Sbjct: 907 EKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAP-EKKDTKEEKAKKP 965

Query: 310 E 310
           E
Sbjct: 966 E 966



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 37/136 (27%), Positives = 62/136 (45%), Gaps = 12/136 (8%)

Query: 184 YLKHLRGQEHKYLLGDAPVS--------PS-SQKLKRKAEEDPEAADSGEPQNKRTPDLP 234
           Y K L G+E +   G  P S        PS S  +K K+EE  +  +  E +     +  
Sbjct: 402 YRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQT 461

Query: 235 EEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQ 294
           EE  V EE+ E EE  K+   E  +E E    +E+    E   +   ++  +PE+++++ 
Sbjct: 462 EETQVTEEVTEEEE--KEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS- 518

Query: 295 PDEEEEEEEEKVSQPE 310
           P +EE +   +   PE
Sbjct: 519 PVKEEAKSPAEAKSPE 534


>gi|211904182 DDB1 and CUL4 associated factor 8-like 2 [Homo
           sapiens]
          Length = 631

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 2/97 (2%)

Query: 218 EAADSGEPQNKRTPDLP-EEEYVKEEIQ-ENEEAVKKMLVEATREFEEVVVDESPPDFEI 275
           ++ D G P +  T +   ++E   E+I+ E+ E  +  L+     F   +V E   + E 
Sbjct: 56  DSRDGGFPNDASTENRSSDQESASEDIELESLEDFEHFLMSGESLFHYPLVGEEETEREE 115

Query: 276 HITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVG 312
                 ++    EE+ E + +EEEEEEEE+  QP  G
Sbjct: 116 EDEEIQEEGGEEEEEEEEEEEEEEEEEEEEEEQPRAG 152


>gi|30795188 Williams Beuren syndrome chromosome region 19 protein
           [Homo sapiens]
          Length = 336

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 64/240 (26%), Positives = 102/240 (42%), Gaps = 56/240 (23%)

Query: 203 SPSSQKL--KRKAEEDPEAADSGEPQNKRTPDLPEEEYVKE-----EIQENEEAVKKMLV 255
           SP  + L  KRK E   E+ +  EP+ +  P+ PEE +V E     +++  ++ V  +L+
Sbjct: 20  SPPCRSLGWKRKREWSDESEE--EPEKELAPE-PEETWVVETLCGLKMKLKQQRVSPILL 76

Query: 256 EATREFEEVV---VDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPE-- 310
           E  ++F   +   VD SPP    H + C        +       EE EEE  KV  PE  
Sbjct: 77  EHHKDFNSQLAPGVDPSPP----HRSFC-----WKRKMEWWDKSEESEEEPRKVLAPEPE 127

Query: 311 --------VGAAIKIIRQLM--------EKFNLDLST-VTQAFLKNSGELEATSAFL--- 350
                    G  +K+ R+ +        E FN  L   V + FL    +L  +  +L   
Sbjct: 128 EIWVAEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAM 187

Query: 351 --ASGQRADGYPIWSRQD---------DIDLQKDDEDTREALVKKFGAQNVARRIEFRKK 399
             A   RA G+P W  Q            D+++DDED+++ +      +N +R    RK+
Sbjct: 188 VIAYFSRA-GFPSWQYQRLHFFLALYLANDMEEDDEDSKQNIFHFLYGKNRSRIPLLRKR 246


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 16/115 (13%)

Query: 207 QKLKRKAEEDPEAADSGEPQNKRTPDLPEE----EYVKEEIQENE-------EAVKKMLV 255
           Q+++ K EE+ E  +S + Q+ +  ++ +     E VK  I + E       E+V+    
Sbjct: 360 QEMEVKMEEETEVRESEKQQDSQPEEVMDVLEMVENVKHVIADQEVMETNRVESVEPSEN 419

Query: 256 EATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
           EA++E E  +  E  PD E     C    P  E  S    ++E EE+EEK S+P+
Sbjct: 420 EASKELEPEMEFEIEPDKE-----CKSLSPGKENVSALDMEKESEEKEEKESEPQ 469



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 36/157 (22%), Positives = 69/157 (43%), Gaps = 27/157 (17%)

Query: 174 QHSWQSLKDRYLKHLRGQEHKYLLG-DAPVSPSSQKLKRKAEEDPEAADSG------EPQ 226
           Q  W     + +K++R +   +L      + P++QKL  +++    A   G      E  
Sbjct: 219 QEEWNEHNAKIIKYIRTKTKPHLFYIPGRMCPATQKLIEESQRKMNALFEGRRIEFAEQI 278

Query: 227 NK-----RTPDLPEEEY--VKEEIQENEEAVKKM------LVEATREFEEVVVDESPPDF 273
           NK     R   + E+E+  V+ E Q+ E+   K+      L E   +  +V ++E+  + 
Sbjct: 279 NKMEARPRRQSMKEKEHQVVRNEEQKAEQEEGKVAQREEELEETGNQHNDVEIEEAGEEE 338

Query: 274 EIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
           E  I +          D+E + +EEE+++E +V   E
Sbjct: 339 EKEIAIV-------HSDAEKEQEEEEQKQEMEVKMEE 368


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 45/184 (24%), Positives = 69/184 (37%), Gaps = 43/184 (23%)

Query: 218 EAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFE--- 274
           E  + G P+ + TP   E E    E ++ E+A          ++E +  DE     E   
Sbjct: 474 EVMEQGVPEKEETPPPVEPE----EEEDTEDA-------GLDDWEAMASDEETEKVEGNK 522

Query: 275 IHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQ 334
           +HI + ++     EE+ E + DEE EEEEE+  + E                        
Sbjct: 523 VHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGS---------------------- 560

Query: 335 AFLKNSGELEATSAFLASGQRADGYPIWSRQDDIDLQKDDEDTREALVKKFGAQNVARRI 394
              +   E E  S    SG+  D  P      D +   DD+ T+E    +       RRI
Sbjct: 561 ---EGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE----ERAYDKAKRRI 613

Query: 395 EFRK 398
           E R+
Sbjct: 614 EKRR 617



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 38/185 (20%), Positives = 77/185 (41%), Gaps = 12/185 (6%)

Query: 206 SQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVV 265
           +QK   K E + +  D  + + ++  +  E E  K++  + +E+ +K   E  +    V 
Sbjct: 229 AQKKAEKKERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVD 288

Query: 266 VDESPPDFEIHITMC----DDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQL 321
               P   E   T      D++    ++D + +  E+EE+E+EK   P   A +K +++ 
Sbjct: 289 TGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPS-KATVKAMQEA 347

Query: 322 MEKFNLDLSTVTQAFLKNSGELEATSAFLASGQRADGYPIWSRQDDIDLQKDDEDTREAL 381
           + K   +     +   +    LE   A     +R +       Q+  + +K  E  R+  
Sbjct: 348 LAKLKEEEERQKREEEERIKRLEELEAKRKEEERLE-------QEKRERKKQKEKERKER 400

Query: 382 VKKFG 386
           +KK G
Sbjct: 401 LKKEG 405



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 20/93 (21%), Positives = 44/93 (47%)

Query: 213 AEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPD 272
           ++E+ E  +  +   +   +  EEE  +EE +E+EE+ ++   E   E  E   ++    
Sbjct: 511 SDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVS 570

Query: 273 FEIHITMCDDDPPTPEEDSETQPDEEEEEEEEK 305
            E       D  P+ E  S+++ D +++  +E+
Sbjct: 571 DEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEE 603


>gi|194595492 speedy homolog E5 [Homo sapiens]
          Length = 337

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 64/236 (27%), Positives = 104/236 (44%), Gaps = 47/236 (19%)

Query: 203 SPSSQKL--KRKAEEDPEAADSGEPQNKRTPDLPEEEYVKE-----EIQENEEAVKKMLV 255
           SP  + L  KRK E   E+A+  EP+ +  P+ PEE +V E     +++  ++ V  +L 
Sbjct: 20  SPPCRSLGWKRKREWSDESAE--EPEKELAPE-PEETWVVEMLCGLKMKLKQQRVSPILP 76

Query: 256 EATREFEEVV---VDESPPDFEIHITMCDDDPPTPEEDSETQPDEEE------EEEEEKV 306
           E  + F   +   VD SPP    H + C        ++SE   +EE       E EE  V
Sbjct: 77  EHHKGFNSQLAPGVDPSPP----HRSFCWKRKMEWWDESEESLEEEPRKVLAPEPEEIWV 132

Query: 307 SQPEVGAAIKIIRQLM--------EKFNLDLST-VTQAFLKNSGELEATSAFL-----AS 352
           ++   G  +K+ R+ +        E FN  L   V + FL    +L  +  +L     A 
Sbjct: 133 AEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAY 192

Query: 353 GQRADGYPIWSRQD---------DIDLQKDDEDTREALVKKFGAQNVARRIEFRKK 399
             RA G+P W  Q            D+++DDED+++ +      +N +R    RK+
Sbjct: 193 FSRA-GFPSWQYQRIHFFLALYLANDMEEDDEDSKQNIFHFLYGKNRSRIPLLRKR 247


>gi|226246595 speedy homolog E6 [Homo sapiens]
          Length = 402

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 63/236 (26%), Positives = 104/236 (44%), Gaps = 47/236 (19%)

Query: 203 SPSSQKL--KRKAEEDPEAADSGEPQNKRTPDLPEEEYVKE-----EIQENEEAVKKMLV 255
           SP  + L  KRK E   E+ +  EP+ +  P+ PEE +V E     +++  ++ V  +L 
Sbjct: 60  SPPCRSLGWKRKREWSDESEE--EPEKELAPE-PEETWVVEMLCGLKMKLKQQRVSSILP 116

Query: 256 EATREFEEVV---VDESPPDFEIHITMCDDDPPTPEEDSETQPDEEE------EEEEEKV 306
           E  ++F   +   VD SPP    H + C        ++SE   +EE       E EE  V
Sbjct: 117 EHHKDFNSQLAPGVDPSPP----HRSFCWKRKMEWWDESEESLEEEPRKVLAPEPEEIWV 172

Query: 307 SQPEVGAAIKIIRQLM--------EKFNLDLST-VTQAFLKNSGELEATSAFL-----AS 352
           ++   G  +K+ R+ +        E FN  L   V + FL    +L  +  +L     A 
Sbjct: 173 AEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAY 232

Query: 353 GQRADGYPIWSRQD---------DIDLQKDDEDTREALVKKFGAQNVARRIEFRKK 399
             RA G+P W  Q            D+++DDED+++ +      +N +R    RK+
Sbjct: 233 FSRA-GFPSWQYQRIHFFLALYLANDMEEDDEDSKQNIFHFLYRKNRSRIPLLRKR 287


>gi|239743297 PREDICTED: speedy homolog E6 [Homo sapiens]
          Length = 402

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 63/236 (26%), Positives = 104/236 (44%), Gaps = 47/236 (19%)

Query: 203 SPSSQKL--KRKAEEDPEAADSGEPQNKRTPDLPEEEYVKE-----EIQENEEAVKKMLV 255
           SP  + L  KRK E   E+ +  EP+ +  P+ PEE +V E     +++  ++ V  +L 
Sbjct: 60  SPPCRSLGWKRKREWSDESEE--EPEKELAPE-PEETWVVEMLCGLKMKLKQQRVSSILP 116

Query: 256 EATREFEEVV---VDESPPDFEIHITMCDDDPPTPEEDSETQPDEEE------EEEEEKV 306
           E  ++F   +   VD SPP    H + C        ++SE   +EE       E EE  V
Sbjct: 117 EHHKDFNSQLAPGVDPSPP----HRSFCWKRKMEWWDESEESLEEEPRKVLAPEPEEIWV 172

Query: 307 SQPEVGAAIKIIRQLM--------EKFNLDLST-VTQAFLKNSGELEATSAFL-----AS 352
           ++   G  +K+ R+ +        E FN  L   V + FL    +L  +  +L     A 
Sbjct: 173 AEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAY 232

Query: 353 GQRADGYPIWSRQD---------DIDLQKDDEDTREALVKKFGAQNVARRIEFRKK 399
             RA G+P W  Q            D+++DDED+++ +      +N +R    RK+
Sbjct: 233 FSRA-GFPSWQYQRIHFFLALYLANDMEEDDEDSKQNIFHFLYRKNRSRIPLLRKR 287


>gi|239508980 PREDICTED: speedy homolog E6 (Xenopus laevis) [Homo
           sapiens]
          Length = 402

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 63/236 (26%), Positives = 104/236 (44%), Gaps = 47/236 (19%)

Query: 203 SPSSQKL--KRKAEEDPEAADSGEPQNKRTPDLPEEEYVKE-----EIQENEEAVKKMLV 255
           SP  + L  KRK E   E+ +  EP+ +  P+ PEE +V E     +++  ++ V  +L 
Sbjct: 60  SPPCRSLGWKRKREWSDESEE--EPEKELAPE-PEETWVVEMLCGLKMKLKQQRVSSILP 116

Query: 256 EATREFEEVV---VDESPPDFEIHITMCDDDPPTPEEDSETQPDEEE------EEEEEKV 306
           E  ++F   +   VD SPP    H + C        ++SE   +EE       E EE  V
Sbjct: 117 EHHKDFNSQLAPGVDPSPP----HRSFCWKRKMEWWDESEESLEEEPRKVLAPEPEEIWV 172

Query: 307 SQPEVGAAIKIIRQLM--------EKFNLDLST-VTQAFLKNSGELEATSAFL-----AS 352
           ++   G  +K+ R+ +        E FN  L   V + FL    +L  +  +L     A 
Sbjct: 173 AEMLCGLKMKLKRRRVSLVLPEHHEAFNRLLEDPVIKRFLAWDKDLRVSDKYLLAMVIAY 232

Query: 353 GQRADGYPIWSRQD---------DIDLQKDDEDTREALVKKFGAQNVARRIEFRKK 399
             RA G+P W  Q            D+++DDED+++ +      +N +R    RK+
Sbjct: 233 FSRA-GFPSWQYQRIHFFLALYLANDMEEDDEDSKQNIFHFLYRKNRSRIPLLRKR 287


>gi|5454088 acidic (leucine-rich) nuclear phosphoprotein 32 family,
           member B [Homo sapiens]
          Length = 251

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 13/106 (12%)

Query: 215 EDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFE 274
           ED EA DS    +    +  +EE   EE +++E+  ++   E   E E+V  DE      
Sbjct: 151 EDQEAPDSDAEVDGVDEEEEDEEGEDEEDEDDEDGEEEEFDEEDDEDEDVEGDE------ 204

Query: 275 IHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQ 320
                  DD    EE+ E   DEE+E+E+E   + E G   K  R+
Sbjct: 205 -------DDDEVSEEEEEFGLDEEDEDEDEDEEEEEGGKGEKRKRE 243


>gi|55956788 nucleolin [Homo sapiens]
          Length = 710

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 33/117 (28%), Positives = 54/117 (46%), Gaps = 14/117 (11%)

Query: 202 VSPSSQKLKRKA----EEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEA 257
           + P++ K    A    +ED E  +  E  +    D  EEE ++    + ++A K + V+A
Sbjct: 170 IEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKA 229

Query: 258 TREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAA 314
               E+   +E   D +      DDD    +ED E   DE++EEEEE+  +  V  A
Sbjct: 230 KNVAEDEDEEEDDEDED------DDD----DEDDEDDDDEDDEEEEEEEEEEPVKEA 276



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 28/99 (28%), Positives = 47/99 (47%), Gaps = 7/99 (7%)

Query: 281 DDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNS 340
           DDD    EED E   DE+E+E+E + +  +  AA        ++ + D         ++ 
Sbjct: 150 DDDS---EEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDED-DEDDDDDEEDD 205

Query: 341 GELEATSAFLASGQR-ADGYPIWSRQ--DDIDLQKDDED 376
            E EA     A G++ A   P+ ++   +D D ++DDED
Sbjct: 206 SEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDED 244


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 30/88 (34%), Positives = 43/88 (48%), Gaps = 1/88 (1%)

Query: 227 NKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPT 286
           N  + D  EEE  +EE +E EE  ++   E   E EE   +E   + E      +++   
Sbjct: 882 NINSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGE 941

Query: 287 PEEDSETQPDEEEEEEEEKVSQPEVGAA 314
            EE+ E + +EEEEE EE V   E G A
Sbjct: 942 LEEEEEEEDEEEEEELEE-VEDLEFGTA 968



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 15/36 (41%), Positives = 23/36 (63%)

Query: 270 PPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEK 305
           PP  E  +T+ + +    EE+ E + +EEEEEEEE+
Sbjct: 871 PPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEE 906



 Score = 32.7 bits (73), Expect = 0.59
 Identities = 33/146 (22%), Positives = 61/146 (41%), Gaps = 3/146 (2%)

Query: 210  KRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDES 269
            + + EED E  +  E +     +  EEE+ +EE +E E  +++   E   E EE + +  
Sbjct: 903  EEEEEEDFEEEEEDEEEYFEEEEEEEEEF-EEEFEEEEGELEEEEEEEDEEEEEELEEVE 961

Query: 270  PPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQ-LMEKFNLD 328
              +F       ++  P P       P  E   + +   +PE G  +++      E+   D
Sbjct: 962  DLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGAD 1021

Query: 329  LS-TVTQAFLKNSGELEATSAFLASG 353
             + T+    L + GE+E      A+G
Sbjct: 1022 TAPTLAPEALPSQGEVEREGESPAAG 1047



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 33/134 (24%), Positives = 51/134 (38%), Gaps = 19/134 (14%)

Query: 199  DAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEAT 258
            D       ++ + + EE+ E  D  E +        EEE  +EE +E  E  +  L E  
Sbjct: 887  DEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEE 946

Query: 259  REFEEVVVDESPPDFEIHITMCDDD-------PPT-------PEEDSETQPDEEEE---- 300
             E +E   +E     ++       +       PPT       PE   + QP+ E E    
Sbjct: 947  EEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPPESPPKVQPEPEPEPGLL 1006

Query: 301  -EEEEKVSQPEVGA 313
             E EE  ++ E GA
Sbjct: 1007 LEVEEPGTEEERGA 1020



 Score = 30.8 bits (68), Expect = 2.3
 Identities = 30/98 (30%), Positives = 41/98 (41%), Gaps = 17/98 (17%)

Query: 217 PEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIH 276
           P+    G P     P L EE+     I  ++E  ++   E   E EE   +E   DFE  
Sbjct: 858 PQLVPEGTPGGGGPPAL-EEDLTVININSSDEEEEE---EEEEEEEEEEEEEEEEDFE-- 911

Query: 277 ITMCDDDPPTPEEDSET--QPDEEEEEEEEKVSQPEVG 312
                      EED E   + +EEEEEE E+  + E G
Sbjct: 912 ---------EEEEDEEEYFEEEEEEEEEFEEEFEEEEG 940


>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
           sapiens]
          Length = 1710

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 51/261 (19%), Positives = 97/261 (37%), Gaps = 56/261 (21%)

Query: 102 GPASAADTGSEAKPGALAEGAAEPEPQRHAGRIAFTDADDVAILTYVKENA--RSPSSVT 159
           G  S + +GS +   +   G+++ +    +G  + +++D        +EN     P  V 
Sbjct: 29  GSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDTS------RENKVQAKPPKVD 82

Query: 160 GNALWK------AMEKSSLT---QHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLK 210
           G   WK      A+++S++    Q   Q  + +   +   +E      D+  S S  K K
Sbjct: 83  GAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSDDSSSEVKRK 142

Query: 211 RKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAV-------------------- 250
           +  +ED + + SG P    +    EEE  K    E E                       
Sbjct: 143 KHKDEDWQMSGSGSPSQSGSDSESEEEREKSSCDETESDYEPKNKVKSRKPQNRSKSKNG 202

Query: 251 KKMLVEATREFEEVVVDESPPDFE-----------IHITMCDDDPPTPEED--------S 291
           KK+L +  R+ +    D+   D++           ++++  +D+    + D         
Sbjct: 203 KKILGQKKRQIDSSEEDDDEEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLEVCGED 262

Query: 292 ETQPDEEEEEEEEKVSQPEVG 312
             QP+EEE E  E+     +G
Sbjct: 263 VPQPEEEEFETIERFMDCRIG 283


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 8/149 (5%)

Query: 163 LWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADS 222
           +W+  EK    +   + ++++  K  R QE K    D  +    +++ R+ E+  E  + 
Sbjct: 348 MWRQEEK---IREQEEKIREQEEKMWR-QEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403

Query: 223 GEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDD 282
            + +  R      E+   E+I+E EE + +   E  RE EE++ D+     E+   M ++
Sbjct: 404 RQEKMWRQEKKMREQ--DEKIREQEEEMWRQ-EEKIRELEEMMQDQEEKLREVEEKMQEE 460

Query: 283 DPPTPEEDSETQPDEEE-EEEEEKVSQPE 310
           +    E++ + Q  EE+ +E+EEK  + E
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 33/152 (21%), Positives = 69/152 (45%), Gaps = 7/152 (4%)

Query: 163 LWKAMEKSSLTQHSWQSLKDRYLKH---LRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEA 219
           +W+  EK    +   +  +D+  +    +R QE K    +  +    +K++   E+D + 
Sbjct: 327 MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR---EQDEKI 383

Query: 220 ADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITM 279
            +  E   ++   + E+E  ++E    +E   +   E  RE EE +  +     E+   M
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443

Query: 280 CDDDPPTPEEDSETQPDEEE-EEEEEKVSQPE 310
            D +    E + + Q +EE+ +E+EEK+ + E
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 29/149 (19%), Positives = 67/149 (44%), Gaps = 16/149 (10%)

Query: 163 LWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADS 222
           +W+  EK    +   Q    R  K +R Q+ K       +    +++ R+ E+  E  + 
Sbjct: 390 MWRQEEKIREQEEKRQEKMWRQEKKMREQDEK-------IREQEEEMWRQEEKIRELEEM 442

Query: 223 GEPQNKRTPDLPEEEYVKEE-IQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCD 281
            + Q ++  ++ E+   +EE +QE EE +++         EE + ++    +     +  
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ--------EEKIQEQEEKTWRQEKLLKQ 494

Query: 282 DDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
           ++    +E+   + +E+  E+EEK+ + E
Sbjct: 495 EEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 7/134 (5%)

Query: 191 QEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAV 250
           QE K    +  +    +K+    E++ +  +  E   ++   + E+E   E+I+E E+ +
Sbjct: 295 QEEKMWRQEEKIQEQEEKM---CEQELKIREQEEKMWRQEEKMHEQE---EKIREQEDKM 348

Query: 251 KKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
            +   E  RE EE + ++    +     + + D    E++ E    EE+  E+E+  Q +
Sbjct: 349 WRQ-EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407

Query: 311 VGAAIKIIRQLMEK 324
           +    K +R+  EK
Sbjct: 408 MWRQEKKMREQDEK 421


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 36/149 (24%), Positives = 72/149 (48%), Gaps = 8/149 (5%)

Query: 163 LWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADS 222
           +W+  EK    +   + ++++  K  R QE K    D  +    +++ R+ E+  E  + 
Sbjct: 348 MWRQEEK---IREQEEKIREQEEKMWR-QEEKIREQDEKIQEQEEEMWRQEEKIREQEEK 403

Query: 223 GEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDD 282
            + +  R      E+   E+I+E EE + +   E  RE EE++ D+     E+   M ++
Sbjct: 404 RQEKMWRQEKKMREQ--DEKIREQEEEMWRQ-EEKIRELEEMMQDQEEKLREVEEKMQEE 460

Query: 283 DPPTPEEDSETQPDEEE-EEEEEKVSQPE 310
           +    E++ + Q  EE+ +E+EEK  + E
Sbjct: 461 EEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 33/152 (21%), Positives = 69/152 (45%), Gaps = 7/152 (4%)

Query: 163 LWKAMEKSSLTQHSWQSLKDRYLKH---LRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEA 219
           +W+  EK    +   +  +D+  +    +R QE K    +  +    +K++   E+D + 
Sbjct: 327 MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIR---EQDEKI 383

Query: 220 ADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITM 279
            +  E   ++   + E+E  ++E    +E   +   E  RE EE +  +     E+   M
Sbjct: 384 QEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMM 443

Query: 280 CDDDPPTPEEDSETQPDEEE-EEEEEKVSQPE 310
            D +    E + + Q +EE+ +E+EEK+ + E
Sbjct: 444 QDQEEKLREVEEKMQEEEEKMQEQEEKIQRQE 475



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 29/149 (19%), Positives = 67/149 (44%), Gaps = 16/149 (10%)

Query: 163 LWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADS 222
           +W+  EK    +   Q    R  K +R Q+ K       +    +++ R+ E+  E  + 
Sbjct: 390 MWRQEEKIREQEEKRQEKMWRQEKKMREQDEK-------IREQEEEMWRQEEKIRELEEM 442

Query: 223 GEPQNKRTPDLPEEEYVKEE-IQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCD 281
            + Q ++  ++ E+   +EE +QE EE +++         EE + ++    +     +  
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ--------EEKIQEQEEKTWRQEKLLKQ 494

Query: 282 DDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
           ++    +E+   + +E+  E+EEK+ + E
Sbjct: 495 EEKIWEQEEKMWRQEEKMWEQEEKMQEQE 523



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 29/134 (21%), Positives = 61/134 (45%), Gaps = 7/134 (5%)

Query: 191 QEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAV 250
           QE K    +  +    +K+    E++ +  +  E   ++   + E+E   E+I+E E+ +
Sbjct: 295 QEEKMWRQEEKIQEQEEKM---CEQELKIREQEEKMWRQEEKMHEQE---EKIREQEDKM 348

Query: 251 KKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQPE 310
            +   E  RE EE + ++    +     + + D    E++ E    EE+  E+E+  Q +
Sbjct: 349 WRQ-EEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEK 407

Query: 311 VGAAIKIIRQLMEK 324
           +    K +R+  EK
Sbjct: 408 MWRQEKKMREQDEK 421


>gi|195976782 Paf1/RNA polymerase II complex component [Homo
           sapiens]
          Length = 710

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 54/261 (20%), Positives = 102/261 (39%), Gaps = 23/261 (8%)

Query: 89  ERNERLELEAYRLGPASAADTGSEAKPGALAEGAAEPEPQRHAGRIAFTDADDVAILTYV 148
           +++   E  A   G  S +D+ S +        + + E     G     D +D A L  +
Sbjct: 140 DKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGEDLMGDEEDRARLEQM 199

Query: 149 KENARSPSSVTGNALWKAMEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQK 208
            E  R         L+  +EK  + +  ++  K   LK  + +E K            +K
Sbjct: 200 TEKEREQE------LFNRIEKREVLKRRFEIKKK--LKTAKKKEKKEKKKKQEEEQEKKK 251

Query: 209 LKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDE 268
           L +  +E    + + E ++KR   L ++    EE++   E  K    E   + + +   E
Sbjct: 252 LTQ-IQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRKNRTAELLAKKQPLKTSE 310

Query: 269 SPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEK--------VSQPEVGAAIKIIRQ 320
              D E      +DD  + + D  ++    +EEEE++        VS PE    +++ R 
Sbjct: 311 VYSDDEEEE---EDDKSSEKSDRSSRTSSSDEEEEKEEIPPKSQPVSLPEELNRVRLSRH 367

Query: 321 LMEKF---NLDLSTVTQAFLK 338
            +E++        TVT  F++
Sbjct: 368 KLERWCHMPFFAKTVTGCFVR 388



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 46/217 (21%), Positives = 91/217 (41%), Gaps = 20/217 (9%)

Query: 168 EKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQN 227
           ++++ T  S  S KD   +    +E +    D+  S SS      +E++      GE   
Sbjct: 128 KQANKTASSGSSDKDSSAESSAPEEGEVSDSDSNSSSSSSDSDSSSEDEEFHDGYGE--- 184

Query: 228 KRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPPDFEIHITMCDDDPPTP 287
               DL  +E  +  +++  E  ++  +    E  EV+       FEI   +        
Sbjct: 185 ----DLMGDEEDRARLEQMTEKEREQELFNRIEKREVLKRR----FEIKKKL---KTAKK 233

Query: 288 EEDSETQPDEEEEEEEEKVSQPEVGAAIKIIRQLMEKFNLDLSTVTQAFLKNSGELE--- 344
           +E  E +  +EEE+E++K++Q +        ++   K +  L   +QA  +   E E   
Sbjct: 234 KEKKEKKKKQEEEQEKKKLTQIQESQVTSHNKERRSKRDEKLDKKSQAMEELKAEREKRK 293

Query: 345 -ATSAFLASGQRADGYPIWSRQDDIDLQKDDEDTREA 380
             T+  LA  Q      ++S  DD + ++DD+ + ++
Sbjct: 294 NRTAELLAKKQPLKTSEVYS--DDEEEEEDDKSSEKS 328


>gi|154759293 cysteine-rich hydrophobic domain 1 [Homo sapiens]
          Length = 224

 Score = 40.4 bits (93), Expect = 0.003
 Identities = 20/50 (40%), Positives = 26/50 (52%)

Query: 260 EFEEVVVDESPPDFEIHITMCDDDPPTPEEDSETQPDEEEEEEEEKVSQP 309
           E EE     S P     ++  DDD    EE+ E + +EEEEEEEE+   P
Sbjct: 21  EEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAP 70



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 18/58 (31%), Positives = 27/58 (46%), Gaps = 7/58 (12%)

Query: 214 EEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPP 271
           EE+  A  S  P +  +   P+++   EE +E EE       E   E EE   +E+PP
Sbjct: 21  EEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEE-------EEEEEEEEEEEEEAPP 71


>gi|33946282 hypothetical protein LOC25962 isoform 1 [Homo sapiens]
          Length = 1812

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 8/107 (7%)

Query: 212 KAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPP 271
           K E+ P   D  EP +     +P+E    +E +  EE  +    E   + ++V V+E   
Sbjct: 207 KEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQE----EGEEDEDDVDVEEEED 262

Query: 272 DFEIHITMCDDDPPTPEEDSETQPDEEEEEE----EEKVSQPEVGAA 314
           + E      D  P   EED E + +E+EE E     E++S  E G A
Sbjct: 263 EDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIA 309


>gi|33946280 hypothetical protein LOC25962 isoform 2 [Homo sapiens]
          Length = 1147

 Score = 40.0 bits (92), Expect = 0.004
 Identities = 31/107 (28%), Positives = 48/107 (44%), Gaps = 8/107 (7%)

Query: 212 KAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVVDESPP 271
           K E+ P   D  EP +     +P+E    +E +  EE  +    E   + ++V V+E   
Sbjct: 207 KEEDAPHREDYFEPISPDRNSVPQEGQYSDEGEVEEEQQE----EGEEDEDDVDVEEEED 262

Query: 272 DFEIHITMCDDDPPTPEEDSETQPDEEEEEE----EEKVSQPEVGAA 314
           + E      D  P   EED E + +E+EE E     E++S  E G A
Sbjct: 263 EDEDDRRTVDSIPEEEEEDEEEEGEEDEEGEGDDGYEQISSDEDGIA 309


>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
           sapiens]
          Length = 482

 Score = 39.7 bits (91), Expect = 0.005
 Identities = 26/112 (23%), Positives = 53/112 (47%), Gaps = 8/112 (7%)

Query: 167 MEKSSLTQHSWQSLKDRYLKHLRGQEHKYLLGDAPVSPSSQKLKRKAEEDPEAADSGEPQ 226
           +E+  L +   Q L + +L   +  + ++      +    ++  +K +E+ E     + +
Sbjct: 58  LEEEKLLERERQRLHEEWLLREQKAQEEFR-----IKKEKEEAAKKRQEEQERKLKEQWE 112

Query: 227 NKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVV---DESPPDFEI 275
            ++  +  EEE  ++E +E EEA++KML +A  E E        E P DF +
Sbjct: 113 EQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRV 164



 Score = 28.9 bits (63), Expect = 8.6
 Identities = 26/117 (22%), Positives = 50/117 (42%), Gaps = 20/117 (17%)

Query: 207 QKLKRKAEEDPEAADSGEPQNKRTPDLPEEEYVKEEIQENEEAVKKMLVEATREFEEVVV 266
           +K K++ +E     DSG  Q +      E+ +++E+  E E+ +++   E  R  EE ++
Sbjct: 25  EKRKKRRQELARLRDSGLSQKEEE----EDTFIEEQQLEEEKLLER---ERQRLHEEWLL 77

Query: 267 DESPPDFEIHITMCDDDPPTP-------------EEDSETQPDEEEEEEEEKVSQPE 310
            E     E  I    ++                 EE    + +EEE++ +EK  + E
Sbjct: 78  REQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEE 134


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.128    0.358 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,562,195
Number of Sequences: 37866
Number of extensions: 919147
Number of successful extensions: 13100
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 177
Number of HSP's successfully gapped in prelim test: 451
Number of HSP's that attempted gapping in prelim test: 7933
Number of HSP's gapped (non-prelim): 2913
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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