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Search of human proteins with 52485941
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
(1035 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|52485941 integrin, alpha 9 precursor [Homo sapiens] 2097 0.0
gi|67191027 integrin alpha 4 precursor [Homo sapiens] 795 0.0
gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens] 321 3e-87
gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens] 320 4e-87
gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [... 315 1e-85
gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [... 313 4e-85
gi|56237029 integrin alpha 5 precursor [Homo sapiens] 303 6e-82
gi|49170034 integrin, alpha 8 [Homo sapiens] 300 5e-81
gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens] 277 3e-74
gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens] 275 1e-73
gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens] 270 4e-72
gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens] 270 5e-72
gi|52485853 integrin, alpha 11 precursor [Homo sapiens] 250 6e-66
gi|223468595 integrin alpha-V isoform 2 [Homo sapiens] 249 7e-66
gi|88758615 integrin alpha 2b preproprotein [Homo sapiens] 249 9e-66
gi|31657142 integrin, alpha 1 precursor [Homo sapiens] 246 1e-64
gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens] 240 6e-63
gi|38569398 integrin, alpha 10 precursor [Homo sapiens] 235 1e-61
gi|34452173 integrin alpha X precursor [Homo sapiens] 216 9e-56
gi|116295258 integrin alpha 2 precursor [Homo sapiens] 216 1e-55
gi|167466217 integrin alpha L isoform b precursor [Homo sapiens] 216 1e-55
gi|167466215 integrin alpha L isoform a precursor [Homo sapiens] 213 8e-55
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 213 1e-54
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 209 8e-54
gi|148728188 integrin, alpha E precursor [Homo sapiens] 207 3e-53
gi|62548866 integrin, alpha D precursor [Homo sapiens] 201 3e-51
gi|29171717 glycosylphosphatidylinositol specific phospholipase ... 59 3e-08
gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo ... 56 2e-07
gi|171184408 solute carrier family 6 (neurotransmitter transport... 36 0.21
gi|171184406 solute carrier family 6 (neurotransmitter transport... 36 0.21
>gi|52485941 integrin, alpha 9 precursor [Homo sapiens]
Length = 1035
Score = 2097 bits (5434), Expect = 0.0
Identities = 1035/1035 (100%), Positives = 1035/1035 (100%)
Query: 1 MGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNT 60
MGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNT
Sbjct: 1 MGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNT 60
Query: 61 RWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDR 120
RWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDR
Sbjct: 61 RWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDR 120
Query: 121 DDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCY 180
DDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCY
Sbjct: 121 DDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCY 180
Query: 181 EEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIM 240
EEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIM
Sbjct: 181 EEYKKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIM 240
Query: 241 NRRYTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKM 300
NRRYTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKM
Sbjct: 241 NRRYTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKM 300
Query: 301 GSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAY 360
GSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAY
Sbjct: 301 GSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAY 360
Query: 361 NAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKIN 420
NAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKIN
Sbjct: 361 NAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKIN 420
Query: 421 PVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAP 480
PVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAP
Sbjct: 421 PVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAP 480
Query: 481 QCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMG 540
QCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMG
Sbjct: 481 QCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMG 540
Query: 541 QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVL 600
QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVL
Sbjct: 541 QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVL 600
Query: 601 RWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNIS 660
RWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNIS
Sbjct: 601 RWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNIS 660
Query: 661 ISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYE 720
ISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYE
Sbjct: 661 ISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYE 720
Query: 721 FSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPT 780
FSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPT
Sbjct: 721 FSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPT 780
Query: 781 SFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEM 840
SFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEM
Sbjct: 781 SFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEM 840
Query: 841 FHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLT 900
FHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLT
Sbjct: 841 FHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLT 900
Query: 901 AHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPE 960
AHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPE
Sbjct: 901 AHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPE 960
Query: 961 EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKN 1020
EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKN
Sbjct: 961 EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKN 1020
Query: 1021 RKENEDSWDWVQKNQ 1035
RKENEDSWDWVQKNQ
Sbjct: 1021 RKENEDSWDWVQKNQ 1035
>gi|67191027 integrin alpha 4 precursor [Homo sapiens]
Length = 1032
Score = 795 bits (2054), Expect = 0.0
Identities = 432/1036 (41%), Positives = 632/1036 (61%), Gaps = 32/1036 (3%)
Query: 7 PRGAGRLRALLLALVVAGIPAGA-YNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLV 65
PR A +R ++ L+ G+P G YN+D + + +QGP ++ FGY+V+ H H RW+LV
Sbjct: 11 PRRAA-VRETVMLLLCLGVPTGRPYNVDTESALLYQGPHNTLFGYSVVLHSHGANRWLLV 69
Query: 66 GAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWM 125
GAP A+ + SV +PGA+++CR+ NP + C +L + G G CGKTC E+RD++W+
Sbjct: 70 GAPTANWLANASVINPGAIYRCRIGKNPGQTCEQLQL--GSPNGEPCGKTCLEERDNQWL 127
Query: 126 GVSLARQPKADGRVLACAHRWKNIYY-EADHILPHGFCYIIPSNLQAK-GRTLIPCYEEY 183
GV+L+RQP +G ++ C HRWKNI+Y + ++ LP G CY +P +L+ + + + PCY++Y
Sbjct: 128 GVTLSRQPGENGSIVTCGHRWKNIFYIKNENKLPTGGCYGVPPDLRTELSKRIAPCYQDY 187
Query: 184 KKKYGEEHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRR 243
KK+GE SCQAGI+ F+T++L+VMGAPGS YW G++ V N+T N Y D+ +
Sbjct: 188 VKKFGENFASCQAGISSFYTKDLIVMGAPGSSYWTGSLFVYNITTNKYKAFLDKQNQVKF 247
Query: 244 YTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSY 303
+YLGY+V AGHF T +VVGGAPQ + IGK YIF D + ++ + GKK+GSY
Sbjct: 248 GSYLGYSVGAGHFRSQHTTEVVGGAPQHEQIGKAYIFSIDEKELNILH--EMKGKKLGSY 305
Query: 304 FGSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGALEEQLA--LTGDGAYN 361
FG+S+CAVDLN DG SDLLVGAPM S IR+EG+V VYIN G+GA+ + L G Y
Sbjct: 306 FGASVCAVDLNADGFSDLLVGAPMQSTIREEGRVFVYINSGSGAVMNAMETNLVGSDKYA 365
Query: 362 AHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINP 421
A FGESI +L D+DNDGF DVAIGAP+EDD GA+YIY+G A GI +S ++ G +I+
Sbjct: 366 ARFGESIVNLGDIDNDGFEDVAIGAPQEDDLQGAIYIYNGRADGISSTFSQRIEGLQISK 425
Query: 422 VLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSIFLPGSINITAPQ 481
L MFGQSISG ID D NGY DV VGAF SDS VLLR RPV+ VD S+ P S+N T
Sbjct: 426 SLSMFGQSISGQIDADNNGYVDVAVGAFRSDSAVLLRTRPVVIVDASLSHPESVNRTKFD 485
Query: 482 CHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQ 541
C + P C+++T CFS+ GK VPG I L Y + DV +K + PR YF G T
Sbjct: 486 CVENGWPSVCIDLTLCFSYKGKEVPGYIVLFYNMSLDVNRKAESP-PRFYFSSNG-TSDV 543
Query: 542 VTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEE-RELPPLTPVL 600
+T +Q++ E CR + A +++ V+D+++PI EAAY L HV + E PPL P+L
Sbjct: 544 ITGSIQVSSREANCRTHQAFMRKDVRDILTPIQIEAAYHLGPHVISKRSTEEFPPLQPIL 603
Query: 601 RWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNIS 660
+ KK + I +K F R C E+C+ADLQ+ K+ E YLA+G++K + LN+S
Sbjct: 604 QQKKEKDIMKKTIN-FARFCAHENCSADLQVSAKIGFLKPHENKTYLAVGSMKTLMLNVS 662
Query: 661 ISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESD---FLKCSVGFPFMRSKS 717
+ N GDDAY+ + + L+FI + + EE I+CE+ ++ L CS+G+ ++ S
Sbjct: 663 LFNAGDDAYETTLHVKLPVGLYFIKILELEEKQINCEVTDNSGVVQLDCSIGYIYVDHLS 722
Query: 718 KYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIM 777
+ + S + D S LS EE LS V A N E ++L + + + +PL +EV ++ G +
Sbjct: 723 RIDISFLLDVSSLSRAEEDLSITVHATCENEEEMDNLKHSRVTVAIPLKYEVKLTVHGFV 782
Query: 778 SPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGG 837
+PTSFVYG + + + C + +N+T V NTG S P SV I PN S
Sbjct: 783 NPTSFVYGSNDEN------EPETCMVEKMNLTFHVINTGNSMAPNVSVEIMVPNSFSPQT 836
Query: 838 AEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQE--NIFHTIFAFFTKSGRKVLDCEKPG 895
++F++ + V G C F+ C + Q++ I F +K+ +++L C K
Sbjct: 837 DKLFNILD--VQTTTGECHFENYQRVCALEQQKSAMQTLKGIVRFLSKTDKRLLYCIKAD 894
Query: 896 ISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIA 955
CL CNF + + ++ I + IL+ D +S ++F RA +P RV+E+
Sbjct: 895 PHCLNFLCNFGKMESGKEASVHIQLEGRPSILEMDETSALKFEIRATGFPEPNPRVIEL- 953
Query: 956 HGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEII 1015
+ + V+ E LH+ P+ Y II+ SLL+G+++ LL++ ++WK GFF+R+YK I+
Sbjct: 954 NKDENVAHVLLEGLHHQRPKRYFTIVIISSSLLLGLIVLLLISYVMWKAGFFKRQYKSIL 1013
Query: 1016 EAEKNRKENEDSWDWV 1031
+ E R DSW ++
Sbjct: 1014 QEENRR----DSWSYI 1025
>gi|222418611 integrin alpha 7 isoform 2 precursor [Homo sapiens]
Length = 1137
Score = 321 bits (822), Expect = 3e-87
Identities = 311/1108 (28%), Positives = 524/1108 (47%), Gaps = 154/1108 (13%)
Query: 7 PRGAGRLRALLLALVVAGI--PAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTR--- 61
P GA + L +L+V + A A+NLD + +G S FG++V H R
Sbjct: 9 PWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQS 68
Query: 62 WVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRD 121
W+LVGAP+A + G +F C + + C +D+ +G + +E ++
Sbjct: 69 WLLVGAPQALALPGQQANRTGGLFACPLSLE-ETDCYRVDIDQGADMQ-------KESKE 120
Query: 122 DEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPH----GFCYIIPSNLQAK----G 173
++W+GVS+ Q G+++ CAHR++ D IL G C+++ +L + G
Sbjct: 121 NQWLGVSVRSQGPG-GKIVTCAHRYE-ARQRVDQILETRDMIGRCFVLSQDLAIRDELDG 178
Query: 174 RTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEE--LVVMGAPGSFYWAGTIKVLNLT---- 227
C E + + E+ G CQ G A F+ + ++ GAPG++ W G + V N+
Sbjct: 179 GEWKFC--EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGLLFVTNIDSSDP 236
Query: 228 DNTYLKLND----------EVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIGK 276
D K D ++ +N +YLG+++ +G + V GAP+ G
Sbjct: 237 DQLVYKTLDPADRLPGPAGDLALN---SYLGFSIDSGKGLVRAEELSFVAGAPRANHKGA 293
Query: 277 VYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE-- 334
V I R D S L+ SG+++ S FG SL DLN DG DL+VGAP F E ++E
Sbjct: 294 VVILRKDSAS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELG 352
Query: 335 GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAG 394
G V VY+N+G G L G+ ++ FG S+A L DL+ DGFPD+A+GAP + D G
Sbjct: 353 GAVYVYLNQG-GHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--G 409
Query: 395 AVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSV 454
V+IYHG + G+V + S L G+ + ++ FG S+SG +DMDGN YPD+ VG+ ++D+
Sbjct: 410 KVFIYHGSSLGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGS-LADTA 466
Query: 455 VLLRARPVITV--DVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGE---- 508
VL RARP++ V +VSI P SI++ P C G C+++ CFS+ VP
Sbjct: 467 VLFRARPILHVSHEVSI-APRSIDLEQPNCAGGHSV--CVDLRVCFSYIA--VPSSYSPT 521
Query: 509 IGLNYVLMADVAKKEKGQMPRVYFVL--LGETMGQVTEKLQLTYM-EETCRHYVAHVKRR 565
+ L+YVL AD ++ +GQ+PRV F+ L E Q + + L + + C + ++
Sbjct: 522 VALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQEN 581
Query: 566 VQDVISPIVFEAAYSLSEHVTGEEE--RELPPLTPVLRWKKGQKIAQKNQTVFERNCRSE 623
V+D + IV +YSL + + LPP+ P+L Q Q+ + F + E
Sbjct: 582 VKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPIL--NAHQPSTQRAEIHFLKQGCGE 639
Query: 624 D--CAADLQL------------QGKLLLSSMDEKTLYLALGAVKNISLNISISNL----- 664
D C ++LQL + + L +D T AL I L + ++NL
Sbjct: 640 DKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPA 699
Query: 665 -----GDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLESDFLKCSVGFPFMRSKS 717
GDDA++A + + L + + E + + ++C +G P M+ +
Sbjct: 700 QPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGA 758
Query: 718 KYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIM 777
+ F +I TS +S E L + + + + + V + E+ SI G+
Sbjct: 759 QVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI-----ELPLSIAGMA 813
Query: 778 SPTSFVYGESVDAANFIQLD-DLECHFQPINITLQVYNTGPS--TLPGSSVSISFPNRLS 834
P + V +Q + D+ + + V N G S TL + ++I +P+ ++
Sbjct: 814 IPQQLFFSGVVRGERAMQSERDVG---SKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIA 870
Query: 835 SGGAEMFHVQ-EMVVGQ---EKGNCSFQKNPTPCII----------------PQEQE--- 871
+G ++ +Q E+ GQ +KG CS P P I+ P++QE
Sbjct: 871 NGKWLLYPMQVELEGGQGPGQKGLCS----PRPNILHLDVDSRDRRRRELEPPEQQEPGE 926
Query: 872 ----NIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIY-MLLNTEI 926
++ + K LDC + +C+ C + + + + ++ L N+
Sbjct: 927 RQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSF--DRAAVLHVWGRLWNSTF 984
Query: 927 LKKDSS-SVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVV----GW 981
L++ S+ ++ + RA + V +++ + + + + V + L+P V W
Sbjct: 985 LEEYSAVKSLEVIVRANITVKSSIKNLML-----RDASTVIPVMVYLDPMAVVAEGVPWW 1039
Query: 982 IIAISLLVGILIFLLLAVLLWKMGFFRR 1009
+I +++L G+L+ LL +LLWKMGFF+R
Sbjct: 1040 VILLAVLAGLLVLALLVLLLWKMGFFKR 1067
>gi|222418613 integrin alpha 7 isoform 1 precursor [Homo sapiens]
Length = 1141
Score = 320 bits (820), Expect = 4e-87
Identities = 310/1109 (27%), Positives = 523/1109 (47%), Gaps = 152/1109 (13%)
Query: 7 PRGAGRLRALLLALVVAGI--PAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTR--- 61
P GA + L +L+V + A A+NLD + +G S FG++V H R
Sbjct: 9 PWGASGICYLFGSLLVELLFSRAVAFNLDVMGALRKEGEPGSLFGFSVALHRQLQPRPQS 68
Query: 62 WVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRD 121
W+LVGAP+A + G +F C + + C +D+ +G + +E ++
Sbjct: 69 WLLVGAPQALALPGQQANRTGGLFACPLSLE-ETDCYRVDIDQGADMQ-------KESKE 120
Query: 122 DEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPH----GFCYIIPSNLQAK----G 173
++W+GVS+ Q G+++ CAHR++ D IL G C+++ +L + G
Sbjct: 121 NQWLGVSVRSQGPG-GKIVTCAHRYE-ARQRVDQILETRDMIGRCFVLSQDLAIRDELDG 178
Query: 174 RTLIPCYEEYKKKYGEEHGSCQAGIAGFFTEE--LVVMGAPGSFYWAGTIKV-------- 223
C E + + E+ G CQ G A F+ + ++ GAPG++ W GT +V
Sbjct: 179 GEWKFC--EGRPQGHEQFGFCQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSA 236
Query: 224 --LNLTDNTY-----LKLNDEVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIG 275
+L D Y + + +I +Y G+++ +G + V GAP+ G
Sbjct: 237 DLAHLDDGPYEAGGEKEQDPRLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKG 296
Query: 276 KVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE- 334
V I R D S L+ SG+++ S FG SL DLN DG DL+VGAP F E ++E
Sbjct: 297 AVVILRKDSAS-RLVPEVMLSGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEEL 355
Query: 335 -GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFA 393
G V VY+N+G G L G+ ++ FG S+A L DL+ DGFPD+A+GAP + D
Sbjct: 356 GGAVYVYLNQG-GHWAGISPLRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD-- 412
Query: 394 GAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDS 453
G V+IYHG + G+V + S L G+ + ++ FG S+SG +DMDGN YPD+ VG+ ++D+
Sbjct: 413 GKVFIYHGSSLGVVAKPSQVLEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGS-LADT 469
Query: 454 VVLLRARPVITV--DVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGE--- 508
VL RARP++ V +VSI P SI++ P C G C+++ CFS+ VP
Sbjct: 470 AVLFRARPILHVSHEVSI-APRSIDLEQPNCAGGHSV--CVDLRVCFSYIA--VPSSYSP 524
Query: 509 -IGLNYVLMADVAKKEKGQMPRVYFVL--LGETMGQVTEKLQLTYM-EETCRHYVAHVKR 564
+ L+YVL AD ++ +GQ+PRV F+ L E Q + + L + + C + ++
Sbjct: 525 TVALDYVLDADTDRRLRGQVPRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQE 584
Query: 565 RVQDVISPIVFEAAYSLSEHVTGEEE--RELPPLTPVLRWKKGQKIAQKNQTVFERNCRS 622
V+D + IV +YSL + + LPP+ P+L Q Q+ + F +
Sbjct: 585 NVKDKLRAIVVTLSYSLQTPRLRRQAPGQGLPPVAPIL--NAHQPSTQRAEIHFLKQGCG 642
Query: 623 ED--CAADLQL------------QGKLLLSSMDEKTLYLALGAVKNISLNISISNL---- 664
ED C ++LQL + + L +D T AL I L + ++NL
Sbjct: 643 EDKICQSNLQLVRARFCTRVSDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDP 702
Query: 665 ------GDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLESDFLKCSVGFPFMRSK 716
GDDA++A + + L + + E + + ++C +G P M+
Sbjct: 703 AQPQADGDDAHEAQLLVMLPDSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRG 761
Query: 717 SKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGI 776
++ F +I TS +S E L + + + + + V + E+ SI G+
Sbjct: 762 AQVTFYLILSTSGISIETTELEVELLLATISEQELHPVSARARVFI-----ELPLSIAGM 816
Query: 777 MSPTSFVYGESVDAANFIQLD-DLECHFQPINITLQVYNTGPS--TLPGSSVSISFPNRL 833
P + V +Q + D+ + + V N G S TL + ++I +P+ +
Sbjct: 817 AIPQQLFFSGVVRGERAMQSERDVG---SKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEI 873
Query: 834 SSGGAEMFHVQ-EMVVGQ---EKGNCSFQKNPTPCII----------------PQEQE-- 871
++G ++ +Q E+ GQ +KG CS P P I+ P++QE
Sbjct: 874 ANGKWLLYPMQVELEGGQGPGQKGLCS----PRPNILHLDVDSRDRRRRELEPPEQQEPG 929
Query: 872 -----NIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIY-MLLNTE 925
++ + K LDC + +C+ C + + + + ++ L N+
Sbjct: 930 ERQEPSMSWWPVSSAEKKKNITLDCARGTANCVVFSCPLYSF--DRAAVLHVWGRLWNST 987
Query: 926 ILKKDSS-SVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVV----G 980
L++ S+ ++ + RA + V +++ + + + + V + L+P V
Sbjct: 988 FLEEYSAVKSLEVIVRANITVKSSIKNLML-----RDASTVIPVMVYLDPMAVVAEGVPW 1042
Query: 981 WIIAISLLVGILIFLLLAVLLWKMGFFRR 1009
W+I +++L G+L+ LL +LLWKMGFF+R
Sbjct: 1043 WVILLAVLAGLLVLALLVLLLWKMGFFKR 1071
>gi|119395742 integrin alpha chain, alpha 6 isoform b precursor [Homo
sapiens]
Length = 1073
Score = 315 bits (807), Expect = 1e-85
Identities = 282/1098 (25%), Positives = 504/1098 (45%), Gaps = 127/1098 (11%)
Query: 10 AGRLRALLLALVVAGIPAGAYNLDPQRP--VHFQGPADSFFGYAVLEHFH---DNTRWVL 64
AG+L L L+ + A+NLD + + G S FG+++ H+ ++ R +L
Sbjct: 4 AGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLL 63
Query: 65 VGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEW 124
VGAP+A++ G ++ C + CT ++ + + E ++D+W
Sbjct: 64 VGAPRAEALPLQRANRTGGLYSCDITARGP--CTRIEFDNDADPTS-------ESKEDQW 114
Query: 125 MGVSLARQPKADGRVLACAHRWK-----NIYYEADHILPHGFCYIIPSNLQAK----GRT 175
MGV++ Q G+V+ CAHR++ N E+ I G CY++ NL+ + G
Sbjct: 115 MGVTVQSQGPG-GKVVTCAHRYEKRQHVNTKQESRDIF--GRCYVLSQNLRIEDDMDGGD 171
Query: 176 LIPCYEEYKKKYGEEHGSCQAGIAGFFTEEL--VVMGAPGSFYWAGTIKVLNLTDNTYLK 233
C + + + E+ GSCQ G+A FT++ +V GAPG++ W G ++V +NT+
Sbjct: 172 WSFC--DGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRV-EQKNNTFFD 228
Query: 234 LN----------------DEVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIGK 276
+N + ++ +YLG+++ +G I V GAP+ G
Sbjct: 229 MNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGA 288
Query: 277 VYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE-- 334
V + + D +S L+ G+ + S FG + VDLN DG D+++GAP + + E
Sbjct: 289 VVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVG 348
Query: 335 GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAG 394
G V VY+N+ G + +G ++ FG ++ ++ D++ DG+PD+A+GAP +D G
Sbjct: 349 GAVYVYMNQ-QGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDD--LG 405
Query: 395 AVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSV 454
V+IYHG A GI + + L G I+P FG SI+G +D+D N YPDV VG+ +SDSV
Sbjct: 406 KVFIYHGSANGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGS-LSDSV 459
Query: 455 VLLRARPVITVDVSIFL-PGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNY 513
+ R+RPVI + +I + P I++ + CL V +CF + ++
Sbjct: 460 TIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGI-CLQVKSCFEYTANPAGYNPSISI 518
Query: 514 V--LMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVIS 571
V L A+ +++ G RV F G E ++ C ++ ++D +
Sbjct: 519 VGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLR 578
Query: 572 PIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQ 630
PI A+ + E + LP + P+L K A + + C ++ C ++L+
Sbjct: 579 PIPITASVEIQEPSSRRRVNSLPEVLPILN-SDEPKTAHIDVHFLKEGCGDDNVCNSNLK 637
Query: 631 LQGKLLL-SSMDEKTLY---------LALGAVKNISLNISISNL----------GDDAYD 670
L+ K +K Y L L K+I+L I+++N GDDA++
Sbjct: 638 LEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHE 697
Query: 671 A--------NVSFNVSRELFFINMWQKEEMGISCELLES-DFLKCSVGFPFMRSKSKYEF 721
A ++++ REL E +SC ++ C +G PF R+ S F
Sbjct: 698 AKLIATFPDTLTYSAYRELRAF-----PEKQLSCVANQNGSQADCELGNPFKRN-SNVTF 751
Query: 722 SVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTS 781
++ T+ ++ + L + + T ++L T V + E+ S++G+ P+
Sbjct: 752 YLVLSTTEVTFDTPDLD--INLKLETTSNQDNLAPITAKAKVVI--ELLLSVSGVAKPSQ 807
Query: 782 FVYGESVDAANFIQLDD-----LECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSG 836
+G +V ++ +D +E F+ IN+ + N G +TL +I +P +S+G
Sbjct: 808 VYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATL-----NIQWPKEISNG 862
Query: 837 GAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQ-----------EQENIFHTIFAFFTKSG 885
++ V+ G EK C QK + + E++ + F+ F +
Sbjct: 863 KWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERK 922
Query: 886 RKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKV 945
+ L+C ++C+ C L + S + + +T + + + + + RA + V
Sbjct: 923 YQTLNC-SVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDV 981
Query: 946 DPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMG 1005
A + + + + VF + + G V WII +++L GIL+ LL +LWK G
Sbjct: 982 TAAAENIRLPNAGTQVRVTVFPSKTVAQYSG-VPWWIILVAILAGILMLALLVFILWKCG 1040
Query: 1006 FFRRRYKEIIEAEKNRKE 1023
FF+R K+ +A ++ E
Sbjct: 1041 FFKRNKKDHYDATYHKAE 1058
>gi|119395740 integrin alpha chain, alpha 6 isoform a precursor [Homo
sapiens]
Length = 1091
Score = 313 bits (803), Expect = 4e-85
Identities = 286/1108 (25%), Positives = 508/1108 (45%), Gaps = 131/1108 (11%)
Query: 10 AGRLRALLLALVVAGIPAGAYNLDPQRP--VHFQGPADSFFGYAVLEHFH---DNTRWVL 64
AG+L L L+ + A+NLD + + G S FG+++ H+ ++ R +L
Sbjct: 4 AGQLCLLYLSAGLLSRLGAAFNLDTREDNVIRKYGDPGSLFGFSLAMHWQLQPEDKRLLL 63
Query: 65 VGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEW 124
VGAP+A++ G ++ C + CT ++ + + E ++D+W
Sbjct: 64 VGAPRAEALPLQRANRTGGLYSCDITARGP--CTRIEFDNDADPTS-------ESKEDQW 114
Query: 125 MGVSLARQPKADGRVLACAHRWK-----NIYYEADHILPHGFCYIIPSNLQAK----GRT 175
MGV++ Q G+V+ CAHR++ N E+ I G CY++ NL+ + G
Sbjct: 115 MGVTVQSQGPG-GKVVTCAHRYEKRQHVNTKQESRDIF--GRCYVLSQNLRIEDDMDGGD 171
Query: 176 LIPCYEEYKKKYGEEHGSCQAGIAGFFTEEL--VVMGAPGSFYWAGTIKVLNLTDNTYLK 233
C + + + E+ GSCQ G+A FT++ +V GAPG++ W G ++V +NT+
Sbjct: 172 WSFC--DGRLRGHEKFGSCQQGVAATFTKDFHYIVFGAPGTYNWKGIVRV-EQKNNTFFD 228
Query: 234 LN----------------DEVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIGK 276
+N + ++ +YLG+++ +G I V GAP+ G
Sbjct: 229 MNIFEDGPYEVGGETEHDESLVPVPANSYLGFSLDSGKGIVSKDEITFVSGAPRANHSGA 288
Query: 277 VYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE-- 334
V + + D +S L+ G+ + S FG + VDLN DG D+++GAP + + E
Sbjct: 289 VVLLKRDMKSAHLLPEHIFDGEGLASSFGYDVAVVDLNKDGWQDIVIGAPQYFDRDGEVG 348
Query: 335 GQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAG 394
G V VY+N+ G + +G ++ FG ++ ++ D++ DG+PD+A+GAP +D G
Sbjct: 349 GAVYVYMNQ-QGRWNNVKPIRLNGTKDSMFGIAVKNIGDINQDGYPDIAVGAPYDD--LG 405
Query: 395 AVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSV 454
V+IYHG A GI + + L G I+P FG SI+G +D+D N YPDV VG+ +SDSV
Sbjct: 406 KVFIYHGSANGINTKPTQVLKG--ISP---YFGYSIAGNMDLDRNSYPDVAVGS-LSDSV 459
Query: 455 VLLRARPVITVDVSIFL-PGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNY 513
+ R+RPVI + +I + P I++ + CL V +CF + ++
Sbjct: 460 TIFRSRPVINIQKTITVTPNRIDLRQKTACGAPSGI-CLQVKSCFEYTANPAGYNPSISI 518
Query: 514 V--LMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVIS 571
V L A+ +++ G RV F G E ++ C ++ ++D +
Sbjct: 519 VGTLEAEKERRKSGLSSRVQFRNQGSEPKYTQELTLKRQKQKVCMEETLWLQDNIRDKLR 578
Query: 572 PIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQ 630
PI A+ + E + LP + P+L K A + + C ++ C ++L+
Sbjct: 579 PIPITASVEIQEPSSRRRVNSLPEVLPILN-SDEPKTAHIDVHFLKEGCGDDNVCNSNLK 637
Query: 631 LQGKLLL-SSMDEKTLY---------LALGAVKNISLNISISNL----------GDDAYD 670
L+ K +K Y L L K+I+L I+++N GDDA++
Sbjct: 638 LEYKFCTREGNQDKFSYLPIQKGVPELVLKDQKDIALEITVTNSPSNPRNPTKDGDDAHE 697
Query: 671 A--------NVSFNVSRELFFINMWQKEEMGISCELLES-DFLKCSVGFPFMRSKSKYEF 721
A ++++ REL E +SC ++ C +G PF R+ S F
Sbjct: 698 AKLIATFPDTLTYSAYRELRAF-----PEKQLSCVANQNGSQADCELGNPFKRN-SNVTF 751
Query: 722 SVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTS 781
++ T+ ++ + L + + T ++L T V + E+ S++G+ P+
Sbjct: 752 YLVLSTTEVTFDTPDLD--INLKLETTSNQDNLAPITAKAKVVI--ELLLSVSGVAKPSQ 807
Query: 782 FVYGESVDAANFIQLDD-----LECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSG 836
+G +V ++ +D +E F+ IN+ + N G +TL +I +P +S+G
Sbjct: 808 VYFGGTVVGEQAMKSEDEVGSLIEYEFRVINLGKPLTNLGTATL-----NIQWPKEISNG 862
Query: 837 GAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQ-----------EQENIFHTIFAFFTKSG 885
++ V+ G EK C QK + + E++ + F+ F +
Sbjct: 863 KWLLYLVKVESKGLEKVTCEPQKEINSLNLTESHNSRKKREITEKQIDDNRKFSLFAERK 922
Query: 886 RKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKV 945
+ L+C ++C+ C L + S + + +T + + + + + RA + V
Sbjct: 923 YQTLNC-SVNVNCVNIRCPLRGLDSKASLILRSRLWNSTFLEEYSKLNYLDILMRAFIDV 981
Query: 946 DPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMG 1005
A + + + + VF + + G V WII +++L GIL+ LL +LWK G
Sbjct: 982 TAAAENIRLPNAGTQVRVTVFPSKTVAQYSG-VPWWIILVAILAGILMLALLVFILWKCG 1040
Query: 1006 FFRR-RYKEII---EAEKNRKENEDSWD 1029
FF+R RY + + A + RKE + D
Sbjct: 1041 FFKRSRYDDSVPRYHAVRIRKEEREIKD 1068
>gi|56237029 integrin alpha 5 precursor [Homo sapiens]
Length = 1049
Score = 303 bits (776), Expect = 6e-82
Identities = 288/1058 (27%), Positives = 471/1058 (44%), Gaps = 103/1058 (9%)
Query: 7 PRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWV--L 64
PR L LLL L+ G +NLD + P GP SFFG++V E + T V L
Sbjct: 19 PRRRPPLLPLLLLLLPPPPRVGGFNLDAEAPAVLSGPPGSFFGFSV-EFYRPGTDGVSVL 77
Query: 65 VGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNR------GTSCGKTCRE 118
VGAPKA++ P V GAV+ C +P + CT ++ +R +S G+ E
Sbjct: 78 VGAPKANTS-QPGVLQGGAVYLCPWGASPTQ-CTPIEFDSKGSRLLESSLSSSEGEEPVE 135
Query: 119 DRDDEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHIL-PHGFCYIIPSNLQAKGRT 175
+ +W G ++ + +LACA + W+ E + + P G CY+ N +
Sbjct: 136 YKSLQWFGATVRAHGSS---ILACAPLYSWRT---EKEPLSDPVGTCYLSTDNF-TRILE 188
Query: 176 LIPCYEEYKKKYGEEHGSCQAGIAGFFTEE-LVVMGAPGSFYWAGTIKVLN---LTDNTY 231
PC ++ G+ G CQ G + FT+ VV+G PGS++W G I + ++ Y
Sbjct: 189 YAPCRSDFSWAAGQ--GYCQGGFSAEFTKTGRVVLGGPGSYFWQGQILSATQEQIAESYY 246
Query: 232 LKLNDEVIMNRRYT----------YLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFR 281
+ ++ + T YLGY+V G FS T D V G P+ Y +
Sbjct: 247 PEYLINLVQGQLQTRQASSIYDDSYLGYSVAVGEFSGDDTEDFVAGVPKGN---LTYGYV 303
Query: 282 ADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEI------RDEG 335
+ ++ SG++M SYFG ++ A D+NGDGL DLLVGAP+ + ++ G
Sbjct: 304 TILNGSDIRSLYNFSGEQMASYFGYAVAATDVNGDGLDDLLVGAPLLMDRTPDGRPQEVG 363
Query: 336 QVTVYINRGNGALEEQ-LALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFA- 393
+V VY+ G L LTG + FG S+ L DLD DG+ DVAIGAP +
Sbjct: 364 RVYVYLQHPAGIEPTPTLTLTGHDEFG-RFGSSLTPLGDLDQDGYNDVAIGAPFGGETQQ 422
Query: 394 GAVYIYHGDAGGIVPQYSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSD 452
G V+++ G GG+ + S L + FG ++ GG D+DGNGYPD+ VG+F D
Sbjct: 423 GVVFVFPGGPGGLGSKPSQVLQPLWAASHTPDFFGSALRGGRDLDGNGYPDLIVGSFGVD 482
Query: 453 SVVLLRARPVITVDVSI-FLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGL 511
V+ R RP+++ S+ P N C PV C+N++ C + GKHV IG
Sbjct: 483 KAVVYRGRPIVSASASLTIFPAMFNPEERSCSLEGNPVACINLSFCLNASGKHVADSIGF 542
Query: 512 NYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQL-TYMEETCRHYVAHVKR--RVQD 568
L D +K+KG + R F L +T+ L + E CR +++ +D
Sbjct: 543 TVELQLD-WQKQKGGVRRALF--LASRQATLTQTLLIQNGAREDCREMKIYLRNESEFRD 599
Query: 569 VISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAA 627
+SPI +SL + L P L ++ +I K Q + + C ++ C
Sbjct: 600 KLSPIHIALNFSLDPQAPVDSH----GLRPALHYQSKSRIEDKAQILLD--CGEDNICVP 653
Query: 628 DLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGD-DAYDANVSFNVSRELFFINM 686
DLQL+ + + ++ LG ++L N+G+ AY+A + E + +
Sbjct: 654 DLQLE-------VFGEQNHVYLGDKNALNLTFHAQNVGEGGAYEAELRVTAPPEAEYSGL 706
Query: 687 WQK--EEMGISCELL---ESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIV 741
+ +SC+ +S L C +G P M++ + + F HL ++ + F
Sbjct: 707 VRHPGNFSSLSCDYFAVNQSRLLVCDLGNP-MKAGASLWGGLRFTVPHLRDTKKTIQFDF 765
Query: 742 TAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLEC 801
S N S+S + + + + + ++ G+ P + ++ S D Q E
Sbjct: 766 QILSKNLNNSQS---DVVSFRLSVEAQAQVTLNGVSKPEAVLFPVS-DWHPRDQPQKEED 821
Query: 802 HFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNP 861
++ ++ N GPS++ + +S P L G ++ +V V G NC+
Sbjct: 822 LGPAVHHVYELINQGPSSISQGVLELSCPQALE--GQQLLYVTR-VTGL---NCTTNHPI 875
Query: 862 TPCIIPQEQENIFH------TIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRT 915
P + + E H SG ++L C P C C L ++ES++
Sbjct: 876 NPKGLELDPEGSLHHQQKREAPSRSSASSGPQILKC--PEAECFRLRCELGPLHQQESQS 933
Query: 916 IDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVE--IAHGNPEEVTVVFEALHNLE 973
+ ++ + + + A K AL++ + P++ V A+ +
Sbjct: 934 LQLHFRVWAKTFLQREHQPFSLQCEAVYK---ALKMPYRILPRQLPQKERQVATAVQWTK 990
Query: 974 PRGY--VVGWIIAISLLVGILIFLLLAVLLWKMGFFRR 1009
G V WII +++L G+L+ LL +L+K+GFF+R
Sbjct: 991 AEGSYGVPLWIIILAILFGLLLLGLLIYILYKLGFFKR 1028
>gi|49170034 integrin, alpha 8 [Homo sapiens]
Length = 1063
Score = 300 bits (768), Expect = 5e-81
Identities = 300/1093 (27%), Positives = 479/1093 (43%), Gaps = 141/1093 (12%)
Query: 4 PAAPRGAGRLRALLLA-LVVAGIPAG---------AYNLDPQRPVHFQGPADSFFGYAVL 53
P A RG +A L+A L A G A+NLD ++ + GP S+FGYAV
Sbjct: 3 PGASRGPRGSQAPLIAPLCCAAAALGMLLWSPACQAFNLDVEKLTVYSGPKGSYFGYAVD 62
Query: 54 EHFHD-NTRWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSC 112
H D T VLVGAPKA++ P + GAV+ C +C ++ NR
Sbjct: 63 FHIPDARTASVLVGAPKANTS-QPDIVEGGAVYYCPWPAEGSAQCRQIPFDTTNNRKIRV 121
Query: 113 GKTCR--EDRDDEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHILPHGFCYIIPSN 168
T E + ++W G ++ G+V+ACA + W+ + + P G CY+ N
Sbjct: 122 NGTKEPIEFKSNQWFGATVKAHK---GKVVACAPLYHWRTLKPTPEKD-PVGTCYVAIQN 177
Query: 169 LQAKGRTLIPCYEEYKKKYGEEHGSCQAGIA-GFFTEELVVMGAPGSFYWAG---TIKVL 224
A PC G+ G CQAG + F+ +++G PGSFYW G T V
Sbjct: 178 FSAYAE-FSPCRNSNADPEGQ--GYCQAGFSLDFYKNGDLIVGGPGSFYWQGQVITASVA 234
Query: 225 NLTDNTYLKLNDEVIMNRRYT----------YLGYAVTAGHFSHPSTIDVVGGAPQD-KG 273
++ N K + + T YLGY+V AG F+ S ++V G P+ +
Sbjct: 235 DIIANYSFKDILRKLAGEKQTEVAPASYDDSYLGYSVAAGEFTGDSQQELVAGIPRGAQN 294
Query: 274 IGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEI-- 331
G V I + T I+ F +G++M SYFG ++ D+N DGL D+LVGAP+F E
Sbjct: 295 FGYVSIINSTDM--TFIQNF--TGEQMASYFGYTVVVSDVNSDGLDDVLVGAPLFMEREF 350
Query: 332 ----RDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAP 387
R+ GQ+ +Y+ + + LTG + FG ++A L DL+ DG+ D+AIG P
Sbjct: 351 ESNPREVGQIYLYLQVSSLLFRDPQILTGTETFG-RFGSAMAHLGDLNQDGYNDIAIGVP 409
Query: 388 -KEDDFAGAVYIYHGDAGGIVPQYSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVT 445
D G V IY+G+ G+ + S L G + V FG ++ G D+D N YPD+
Sbjct: 410 FAGKDQRGKVLIYNGNKDGLNTKPSQVLQGVWASHAVPSGFGFTLRGDSDIDKNDYPDLI 469
Query: 446 VGAFMSDSVVLLRARPVITVDVSIFL-PGSINITAPQCH--DGQQPVNCLNVTTCFSFHG 502
VGAF + V + RARPV+TVD + L P IN+ C D C ++ C S G
Sbjct: 470 VGAFGTGKVAVYRARPVVTVDAQLLLHPMIINLENKTCQVPDSMTSAACFSLRVCASVTG 529
Query: 503 KHVPGEIGLNYVLMADV---AKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYV 559
+ + I VLMA+V + K+KG + R F L +V + C+ ++
Sbjct: 530 QSIANTI----VLMAEVQLDSLKQKGAIKRTLF-LDNHQAHRVFPLVIKRQKSHQCQDFI 584
Query: 560 AHVKRRVQ--DVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFE 617
+++ + D +SPI YSL E T +E E+ P+ R V E
Sbjct: 585 VYLRDETEFRDKLSPINISLNYSLDES-TFKEGLEVKPILNYYR----------ENIVSE 633
Query: 618 RNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNV 677
+ DC D L LS+ +K + +G ++ L I+ N G+ AY+A + +
Sbjct: 634 QAHILVDCGEDNLCVPDLKLSARPDKH-QVIIGDENHLMLIINARNEGEGAYEAELFVMI 692
Query: 678 SRELFFINMWQKEE--MGISCELLESDFLK---CSVGFPFMRSKSKYEFSVIFDTSHLSG 732
E ++ + + + +SCE + + C +G P M S + Y + F L
Sbjct: 693 PEEADYVGIERNNKGFRPLSCEYKMENVTRMVVCDLGNP-MVSGTNYSLGLRFAVPRLEK 751
Query: 733 EEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAAN 792
++F + +S N + +S N + L + + I G+ P V
Sbjct: 752 TNMSINFDLQIRSSNKDNPDS---NFVSLQINITAVAQVEIRGVSHPPQIV--------- 799
Query: 793 FIQLDDLECHFQP---------INITLQVYNTGPSTLPGSSVSISFP-NRLSSGGAEMFH 842
+ + + E +P + +++N GPST+ + + + +P + +FH
Sbjct: 800 -LPIHNWEPEEEPHKEEEVGPLVEHIYELHNIGPSTISDTILEVGWPFSARDEFLLYIFH 858
Query: 843 VQEMVVGQEKGNCSFQKNPT-------PCIIPQE---------QENIFHT-------IFA 879
+Q + G Q NP P P++ I H +
Sbjct: 859 IQTL------GPLQCQPNPNINPQDIKPAASPEDTPELSAFLRNSTIPHLVRKRDVHVVE 912
Query: 880 FFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLL--NTEILKKDSSSVIQF 937
F +S K+L+C I CL C L ES + + L +T + +K+ +
Sbjct: 913 FHRQSPAKILNC--TNIECLQISCAVGRLEGGESAVLKVRSRLWAHTFLQRKNDPYALAS 970
Query: 938 MSRAKVKVDPAL-RVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLL 996
+ +VK P + ++ G+ T V A N+ + W+I +++L+G+L+ +
Sbjct: 971 LVSFEVKKMPYTDQPAKLPEGSIAIKTSVIWATPNVS--FSIPLWVIILAILLGLLVLAI 1028
Query: 997 LAVLLWKMGFFRR 1009
L + LWK GFF R
Sbjct: 1029 LTLALWKCGFFDR 1041
>gi|222418615 integrin alpha 7 isoform 3 [Homo sapiens]
Length = 1044
Score = 277 bits (709), Expect = 3e-74
Identities = 272/969 (28%), Positives = 456/969 (47%), Gaps = 138/969 (14%)
Query: 142 CAHRWKNIYYEADHILPH----GFCYIIPSNLQAK----GRTLIPCYEEYKKKYGEEHGS 193
CAHR++ D IL G C+++ +L + G C E + + E+ G
Sbjct: 43 CAHRYE-ARQRVDQILETRDMIGRCFVLSQDLAIRDELDGGEWKFC--EGRPQGHEQFGF 99
Query: 194 CQAGIAGFFTEE--LVVMGAPGSFYWAGTIKV----------LNLTDNTY-----LKLND 236
CQ G A F+ + ++ GAPG++ W GT +V +L D Y + +
Sbjct: 100 CQQGTAAAFSPDSHYLLFGAPGTYNWKGTARVELCAQGSADLAHLDDGPYEAGGEKEQDP 159
Query: 237 EVIMNRRYTYLGYAVTAGH-FSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQA 295
+I +Y G+++ +G + V GAP+ G V I R D S L+
Sbjct: 160 RLIPVPANSYFGFSIDSGKGLVRAEELSFVAGAPRANHKGAVVILRKDSAS-RLVPEVML 218
Query: 296 SGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE--GQVTVYINRGNGALEEQLA 353
SG+++ S FG SL DLN DG DL+VGAP F E ++E G V VY+N+G G
Sbjct: 219 SGERLTSGFGYSLAVADLNSDGWPDLIVGAPYFFERQEELGGAVYVYLNQG-GHWAGISP 277
Query: 354 LTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMK 413
L G+ ++ FG S+A L DL+ DGFPD+A+GAP + D G V+IYHG + G+V + S
Sbjct: 278 LRLCGSPDSMFGISLAVLGDLNQDGFPDIAVGAPFDGD--GKVFIYHGSSLGVVAKPSQV 335
Query: 414 LSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITV--DVSIFL 471
L G+ + ++ FG S+SG +DMDGN YPD+ VG+ ++D+ VL RARP++ V +VSI
Sbjct: 336 LEGEAVG--IKSFGYSLSGSLDMDGNQYPDLLVGS-LADTAVLFRARPILHVSHEVSI-A 391
Query: 472 PGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGE----IGLNYVLMADVAKKEKGQM 527
P SI++ P C G C+++ CFS+ VP + L+YVL AD ++ +GQ+
Sbjct: 392 PRSIDLEQPNCAGGHSV--CVDLRVCFSYIA--VPSSYSPTVALDYVLDADTDRRLRGQV 447
Query: 528 PRVYFVL--LGETMGQVTEKLQLTYM-EETCRHYVAHVKRRVQDVISPIVFEAAYSLSEH 584
PRV F+ L E Q + + L + + C + ++ V+D + IV +YSL
Sbjct: 448 PRVTFLSRNLEEPKHQASGTVWLKHQHDRVCGDAMFQLQENVKDKLRAIVVTLSYSLQTP 507
Query: 585 VTGEEE--RELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED--CAADLQL--------- 631
+ + LPP+ P+L Q Q+ + F + ED C ++LQL
Sbjct: 508 RLRRQAPGQGLPPVAPIL--NAHQPSTQRAEIHFLKQGCGEDKICQSNLQLVRARFCTRV 565
Query: 632 ---QGKLLLSSMDEKTLYLALGAVKNISLNISISNL----------GDDAYDANVSFNVS 678
+ + L +D T AL I L + ++NL GDDA++A + +
Sbjct: 566 SDTEFQPLPMDVDGTTALFALSGQPVIGLELMVTNLPSDPAQPQADGDDAHEAQLLVMLP 625
Query: 679 RELFF--INMWQKEEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEV 736
L + + E + + ++C +G P M+ ++ F +I TS +S E
Sbjct: 626 DSLHYSGVRALDPAEKPLCLSNENASHVECELGNP-MKRGAQVTFYLILSTSGISIETTE 684
Query: 737 LSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQL 796
L + + + + + V + E+ SI G+ P + V +Q
Sbjct: 685 LEVELLLATISEQELHPVSARARVFI-----ELPLSIAGMAIPQQLFFSGVVRGERAMQS 739
Query: 797 D-DLECHFQPINITLQVYNTGPS--TLPGSSVSISFPNRLSSGGAEMFHVQ-EMVVGQ-- 850
+ D+ + + V N G S TL + ++I +P+ +++G ++ +Q E+ GQ
Sbjct: 740 ERDVG---SKVKYEVTVSNQGQSLRTLGSAFLNIMWPHEIANGKWLLYPMQVELEGGQGP 796
Query: 851 -EKGNCSFQKNPTPCII----------------PQEQE-------NIFHTIFAFFTKSGR 886
+KG CS P P I+ P++QE ++ + K
Sbjct: 797 GQKGLCS----PRPNILHLDVDSRDRRRRELEPPEQQEPGERQEPSMSWWPVSSAEKKKN 852
Query: 887 KVLDCEKPGISCLTAHCNFSALAKEESRTIDIY-MLLNTEILKKDSS-SVIQFMSRAKVK 944
LDC + +C+ C + + + + ++ L N+ L++ S+ ++ + RA +
Sbjct: 853 ITLDCARGTANCVVFSCPLYSF--DRAAVLHVWGRLWNSTFLEEYSAVKSLEVIVRANIT 910
Query: 945 VDPALRVVEIAHGNPEEVTVVFEALHNLEPRGYVV----GWIIAISLLVGILIFLLLAVL 1000
V +++ + + + + V + L+P V W+I +++L G+L+ LL +L
Sbjct: 911 VKSSIKNLML-----RDASTVIPVMVYLDPMAVVAEGVPWWVILLAVLAGLLVLALLVLL 965
Query: 1001 LWKMGFFRR 1009
LWKMGFF+R
Sbjct: 966 LWKMGFFKR 974
>gi|4504747 integrin alpha 3 isoform a precursor [Homo sapiens]
Length = 1051
Score = 275 bits (704), Expect = 1e-73
Identities = 274/1084 (25%), Positives = 477/1084 (44%), Gaps = 114/1084 (10%)
Query: 3 GPAAPRGAGRLRALLLALVVA--GIPAGAYNLDPQ-RPVHFQGPADSFFGYAVLEHFHDN 59
GP+ A RL LAL+VA G A+NLD + V G S FGY+V H
Sbjct: 4 GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63
Query: 60 TRW---VLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTC 116
+ +L GAP+ + GAV+ C + + D C +++ + G
Sbjct: 64 RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDD-CERMNITVKNDPG------- 115
Query: 117 REDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEA--DHILPHGFCYIIPSNLQAKGR 174
+D W+GV++A Q A GRVL CAHR+ + + D G CY+ ++L+
Sbjct: 116 HHIIEDMWLGVTVASQGPA-GRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSS 174
Query: 175 TLIPCYEEYKKKYGEEH---GSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVL-----NL 226
Y ++ G CQ G +G FT+ V GAPG++ W G ++ +L
Sbjct: 175 DDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDL 234
Query: 227 TDNTYLKLNDEVIMNRRYTYLGYAVTAGHFS-HPSTIDVVGGAPQDKGIGKVYIFRADRR 285
++ +Y D+ + Y+GY + G F HP I +V GAP+ + +G V++ +
Sbjct: 235 SEYSYKDPEDQGNL-----YIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLL-SQEA 288
Query: 286 SGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE--GQVTVYINR 343
G L + G ++G+YFGS++ DLN DG DLLVGAP + E ++E G + V++N+
Sbjct: 289 GGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQ 348
Query: 344 GNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDA 403
+ +L G + FG S+AS+ D++ DGF D+A+GAP E G VYIYH +
Sbjct: 349 AGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSS 406
Query: 404 GGIVPQYSMKLSGQKIN-PVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPV 462
G++ Q + G+K+ P L FG S+SG +D+D N YPD+ VG+ +SD +VLLRARPV
Sbjct: 407 KGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGS-LSDHIVLLRARPV 465
Query: 463 ITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFH----GKHVPGEIGLNYVLMAD 518
I + +P + C +C+ V CF+++ + I L Y L AD
Sbjct: 466 INIVHKTLVPRPAVLDPALC----TATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEAD 521
Query: 519 VAKKEKGQMPRVYFVLLGETMGQVTEKLQ--LTYMEETCRHYVAHVKRRVQDVISPIVFE 576
++ PR+ F G + + E C+ + ++D + PI+
Sbjct: 522 RDRRP----PRLRFA------GSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIIS 571
Query: 577 AAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQLQGKL 635
YSL + L L + Q + + F++ C ++ C ++LQ++
Sbjct: 572 MNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAF 631
Query: 636 LLSSMDEKTLYLALGAVKNISLNISISNL------GDDAYDANVSFNVSRELFFINMWQK 689
+ + + V+ + L+I+++N G+DA++A ++ V L ++
Sbjct: 632 VSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPP 691
Query: 690 EEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTE 749
+C+ E+ F C +G PF R++ + E + F+ ++ L V Q +
Sbjct: 692 G----ACQANETIF--CELGNPFKRNQ-RMELLIAFEVIGVTLHTRDLQ--VQLQLSTSS 742
Query: 750 RSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINIT 809
++L L L+V + + TS++ + +G +V + + +E P+
Sbjct: 743 HQDNLWPMILTLLVD--YTLQTSLSMVNHRLQSFFGGTVMGES--GMKTVEDVGSPLKYE 798
Query: 810 LQVYNTGPST--LPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCII- 866
QV G L + + +P +S+G ++ + V GN S+ P +I
Sbjct: 799 FQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITV----HGNGSWPCRPPGDLIN 854
Query: 867 ---------------PQEQENIFH----------TIFAFFTKSGRKVLDCEKPGISCLTA 901
PQ + T+ A VL C C+
Sbjct: 855 PLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWL 914
Query: 902 HCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNP-E 960
C + T+ + +T I ++ A + + ++ + + +
Sbjct: 915 ECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWF 974
Query: 961 EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRR-RYKEIIEAEK 1019
V + E + L + W++ +++ G+L+ L+ +LLWK GFF+R R + + EA++
Sbjct: 975 SVDIDSELVEELPAE--IELWLVLVAVGAGLLLLGLIILLLWKCGFFKRARTRALYEAKR 1032
Query: 1020 NRKE 1023
+ E
Sbjct: 1033 QKAE 1036
>gi|6006011 integrin alpha 3 isoform b precursor [Homo sapiens]
Length = 1066
Score = 270 bits (691), Expect = 4e-72
Identities = 272/1076 (25%), Positives = 472/1076 (43%), Gaps = 114/1076 (10%)
Query: 3 GPAAPRGAGRLRALLLALVVA--GIPAGAYNLDPQ-RPVHFQGPADSFFGYAVLEHFHDN 59
GP+ A RL LAL+VA G A+NLD + V G S FGY+V H
Sbjct: 4 GPSRAPRAPRLMLCALALMVAAGGCVVSAFNLDTRFLVVKEAGNPGSLFGYSVALHRQTE 63
Query: 60 TRW---VLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTC 116
+ +L GAP+ + GAV+ C + + D C +++ + G
Sbjct: 64 RQQRYLLLAGAPRELAVPDGYTNRTGAVYLCPLTAHKDD-CERMNITVKNDPG------- 115
Query: 117 REDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEA--DHILPHGFCYIIPSNLQAKGR 174
+D W+GV++A Q A GRVL CAHR+ + + D G CY+ ++L+
Sbjct: 116 HHIIEDMWLGVTVASQGPA-GRVLVCAHRYTQVLWSGSEDQRRMVGKCYVRGNDLELDSS 174
Query: 175 TLIPCYEEYKKKYGEEH---GSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVL-----NL 226
Y ++ G CQ G +G FT+ V GAPG++ W G ++ +L
Sbjct: 175 DDWQTYHNEMCNSNTDYLETGMCQLGTSGGFTQNTVYFGAPGAYNWKGNSYMIQRKEWDL 234
Query: 227 TDNTYLKLNDEVIMNRRYTYLGYAVTAGHFS-HPSTIDVVGGAPQDKGIGKVYIFRADRR 285
++ +Y D+ + Y+GY + G F HP I +V GAP+ + +G V++ +
Sbjct: 235 SEYSYKDPEDQGNL-----YIGYTMQVGSFILHPKNITIVTGAPRHRHMGAVFLL-SQEA 288
Query: 286 SGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE--GQVTVYINR 343
G L + G ++G+YFGS++ DLN DG DLLVGAP + E ++E G + V++N+
Sbjct: 289 GGDLRRRQVLEGSQVGAYFGSAIALADLNNDGWQDLLVGAPYYFERKEEVGGAIYVFMNQ 348
Query: 344 GNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDA 403
+ +L G + FG S+AS+ D++ DGF D+A+GAP E G VYIYH +
Sbjct: 349 AGTSFPAHPSLLLHGPSGSAFGLSVASIGDINQDGFQDIAVGAPFEG--LGKVYIYHSSS 406
Query: 404 GGIVPQYSMKLSGQKIN-PVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPV 462
G++ Q + G+K+ P L FG S+SG +D+D N YPD+ VG+ +SD +VLLRARPV
Sbjct: 407 KGLLRQPQQVIHGEKLGLPGLATFGYSLSGQMDVDENFYPDLLVGS-LSDHIVLLRARPV 465
Query: 463 ITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFH----GKHVPGEIGLNYVLMAD 518
I + +P + C +C+ V CF+++ + I L Y L AD
Sbjct: 466 INIVHKTLVPRPAVLDPALC----TATSCVQVELCFAYNQSAGNPNYRRNITLAYTLEAD 521
Query: 519 VAKKEKGQMPRVYFVLLGETMGQVTEKLQ--LTYMEETCRHYVAHVKRRVQDVISPIVFE 576
++ PR+ F G + + E C+ + ++D + PI+
Sbjct: 522 RDRRP----PRLRFA------GSESAVFHGFFSMPEMRCQKLELLLMDNLRDKLRPIIIS 571
Query: 577 AAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQLQGKL 635
YSL + L L + Q + + F++ C ++ C ++LQ++
Sbjct: 572 MNYSLPLRMPDRPRLGLRSLDAYPILNQAQALENHTEVQFQKECGPDNKCESNLQMRAAF 631
Query: 636 LLSSMDEKTLYLALGAVKNISLNISISNL------GDDAYDANVSFNVSRELFFINMWQK 689
+ + + V+ + L+I+++N G+DA++A ++ V L ++
Sbjct: 632 VSEQQQKLSRLQYSRDVRKLLLSINVTNTRTSERSGEDAHEALLTLVVPPALLLSSVRPP 691
Query: 690 EEMGISCELLESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTE 749
+C+ E+ F C +G PF R++ + E + F+ ++ L V Q +
Sbjct: 692 G----ACQANETIF--CELGNPFKRNQ-RMELLIAFEVIGVTLHTRDLQ--VQLQLSTSS 742
Query: 750 RSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINIT 809
++L L L+V + + TS++ + +G +V + + +E P+
Sbjct: 743 HQDNLWPMILTLLVD--YTLQTSLSMVNHRLQSFFGGTVMGES--GMKTVEDVGSPLKYE 798
Query: 810 LQVYNTGPST--LPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCII- 866
QV G L + + +P +S+G ++ + V GN S+ P +I
Sbjct: 799 FQVGPMGEGLVGLGTLVLGLEWPYEVSNGKWLLYPTEITV----HGNGSWPCRPPGDLIN 854
Query: 867 ---------------PQEQENIFH----------TIFAFFTKSGRKVLDCEKPGISCLTA 901
PQ + T+ A VL C C+
Sbjct: 855 PLNLTLSDPGDRPSSPQRRRRQLDPGGGQGPPPVTLAAAKKAKSETVLTCATGRAHCVWL 914
Query: 902 HCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNP-E 960
C + T+ + +T I ++ A + + ++ + + +
Sbjct: 915 ECPIPDAPVVTNVTVKARVWNSTFIEDYRDFDRVRVNGWATLFLRTSIPTINMENKTTWF 974
Query: 961 EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRR-RYKEII 1015
V + E + L + W++ +++ G+L+ L+ +LLWK FF+R RY +I+
Sbjct: 975 SVDIDSELVEELPAE--IELWLVLVAVGAGLLLLGLIILLLWKCDFFKRTRYYQIM 1028
>gi|4504763 integrin alpha-V isoform 1 precursor [Homo sapiens]
Length = 1048
Score = 270 bits (690), Expect = 5e-72
Identities = 284/1102 (25%), Positives = 492/1102 (44%), Gaps = 139/1102 (12%)
Query: 7 PRGAGRLRALLLALVVAGIP---AGAYNLDPQRPVHFQGPADSFFGYAVLEHF---HDNT 60
PR RL L L+++G+ A+NLD P + GP S+FG+AV + F +
Sbjct: 5 PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAV-DFFVPSASSR 63
Query: 61 RWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDR 120
++LVGAPKA++ P + G V KC + RRC ++ NR + E +
Sbjct: 64 MFLLVGAPKANTT-QPGIVEGGQVLKC--DWSSTRRCQPIEFDATGNRDYAKDDPL-EFK 119
Query: 121 DDEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIP 178
+W G S+ + K D ++LACA + W+ + P G C++ K P
Sbjct: 120 SHQWFGASV--RSKQD-KILACAPLYHWRTEMKQERE--PVGTCFLQDGT---KTVEYAP 171
Query: 179 CYEEYKKKYGEEHGSCQAGIAGFFTE-ELVVMGAPGSFYWAGTI------KVLNLTD-NT 230
C + G+ G CQ G + FT+ + V++G PGSFYW G + ++++ D N
Sbjct: 172 CRSQDIDADGQ--GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNV 229
Query: 231 Y-LKLNDEVIMNRRY-----TYLGYAVTAGHFSHPSTIDVVGGAPQD-KGIGKVYIFRAD 283
Y +K N+++ +YLGY+V G F+ D V G P+ + +G VYI+
Sbjct: 230 YSIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGK 289
Query: 284 RRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSE------IRDEGQV 337
S ++ +G++M +YFG S+ A D+NGD +D+ +GAP+F + +++ GQV
Sbjct: 290 NMSS----LYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQV 345
Query: 338 TVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE-DDFAGAV 396
+V + R +G + L G + A FG +IA L DLD DGF D+AI AP +D G V
Sbjct: 346 SVSLQRASGDFQTT-KLNGFEVF-ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIV 403
Query: 397 YIYHGDAGGIVPQYSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVV 455
YI++G + G+ S L GQ + FG S+ G D+D NGYPD+ VGAF D +
Sbjct: 404 YIFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAI 463
Query: 456 LLRARPVITVDVSI-FLPGSINITAPQCH--DGQQPVNCLNVTTCFSFHGKHV-PGEIGL 511
L RARPVITV+ + P +N C V+C NV C GK V P ++
Sbjct: 464 LYRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNF 523
Query: 512 NYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVK--RRVQDV 569
L+ D K+KG + R F+ + + + C +A+++ +D
Sbjct: 524 QVELLLD-KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQ-CEELIAYLRDESEFRDK 581
Query: 570 ISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADL 629
++PI Y L + L P+L I+++ + DC D
Sbjct: 582 LTPITIFMEYRLDYRTAA----DTTGLQPILNQFTPANISRQAHILL-------DCGEDN 630
Query: 630 QLQGKLLLS-SMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQ 688
+ KL +S D+K +Y +G ++L + N G+ AY+A + ++ + FI + +
Sbjct: 631 VCKPKLEVSVDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVR 688
Query: 689 KEE--MGISCELLESDFLK---CSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTA 743
E +SC + + C +G P M++ ++ + F S + + F +
Sbjct: 689 NNEALARLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQI 747
Query: 744 QSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHF 803
QS N L D + + H+VD ++ + + G S F+ + + E
Sbjct: 748 QSSN------LFDKVSPV---VSHKVDLAVLAAVE----IRGVSSPDHIFLPIPNWEHKE 794
Query: 804 QP---------INITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGN 854
P + ++ N GPS+ + + + +P + ++ ++ + + G
Sbjct: 795 NPETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNN-NTLLYILHYDIDGPMNCT 853
Query: 855 CSFQKNPTPCIIPQ--------------EQENIFHTIFAFFTKSGRKVLDCEKPGIS-CL 899
+ NP I E++++ ++ L C G++ CL
Sbjct: 854 SDMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGC---GVAQCL 910
Query: 900 TAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGN- 958
C L + +S + + LL TE + + +K + V+E + N
Sbjct: 911 KIVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSY----SLKSSASFNVIEFPYKNL 966
Query: 959 -PEEVT----VVFEALHNLEPRGYVVG-WIIAISLLVGILIFLLLAVLLWKMGFFRR--- 1009
E++T V ++P V W+I +++L G+L+ +L ++++MGFF+R
Sbjct: 967 PIEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRP 1026
Query: 1010 ----RYKEIIEAEKNRKENEDS 1027
+ +E ++ +N + N ++
Sbjct: 1027 PQEEQEREQLQPHENGEGNSET 1048
>gi|52485853 integrin, alpha 11 precursor [Homo sapiens]
Length = 1188
Score = 250 bits (638), Expect = 6e-66
Identities = 243/865 (28%), Positives = 394/865 (45%), Gaps = 101/865 (11%)
Query: 195 QAGIAGFFTEELVVMGAPGSFYWAGTI-------KVLNLTDNTYLKLNDEVIMNRRYTYL 247
Q G + E+ V++GA G++ W G + KV+ L ++ YLK E + N YL
Sbjct: 368 QTGFSSHVVEDGVLLGAVGAYDWNGAVLKETSAGKVIPLRES-YLKEFPEELKNHG-AYL 425
Query: 248 GYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRA-DRRSGTLIKIFQASGKKMGSYFGS 306
GY VT+ S + V GAP+ GKV +F + RS T+ + + G+++GSYFGS
Sbjct: 426 GYTVTSVVSSRQGRV-YVAGAPRFNHTGKVILFTMHNNRSLTIHQAMR--GQQIGSYFGS 482
Query: 307 SLCAVDLNGDGLSD-LLVGAPM-FSEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHF 364
+ +VD++GDG++D LLVGAPM F+E R+ G+V VY R N + NA F
Sbjct: 483 EITSVDIDGDGVTDVLLVGAPMYFNEGRERGKVYVYELRQNLFVYNGTLKDSHSYQNARF 542
Query: 365 GESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLR 424
G SIAS+ DL+ D + DV +GAP ED+ AGA+YI+HG G I+ +++ ++ L+
Sbjct: 543 GSSIASVRDLNQDSYNDVVVGAPLEDNHAGAIYIFHGFRGSILKTPKQRITASELATGLQ 602
Query: 425 MFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQCH 483
FG SI G +D++ +G D+ VGA + V+L +RPV+ ++ S+ F P INI C
Sbjct: 603 YFGCSIHGQLDLNEDGLIDLAVGAL--GNAVILWSRPVVQINASLHFEPSKINIFHRDCK 660
Query: 484 DGQQPVNCLNVTTCFS--FHGKHV-PGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMG 540
+ CL CF+ F H +G+ Y D E+ PR + G+
Sbjct: 661 RSGRDATCLAAFLCFTPIFLAPHFQTTTVGIRYNATMD----ERRYTPRAHLDEGGDRF- 715
Query: 541 QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVL 600
+ L+ +E C HV D + P+ F YSL + P P+L
Sbjct: 716 -TNRAVLLSSGQELCERINFHV-LDTADYVKPVTFSVEYSLED----------PDHGPML 763
Query: 601 RWKKGQKIAQKNQTVFERNC-RSEDCAADLQLQGKL-LLSSMD----------------- 641
G + F C E C DL L + L ++M+
Sbjct: 764 --DDGWPTTLRVSVPFWNGCNEDEHCVPDLVLDARSDLPTAMEYCQRVLRKPAQDCSAYT 821
Query: 642 ---EKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEM--GISC 696
+ T+++ + +++ ++ N G++AY ++ + S L F ++ QKE+ I C
Sbjct: 822 LSFDTTVFIIESTRQRVAVEATLENRGENAYSTVLNISQSANLQFASLIQKEDSDGSIEC 881
Query: 697 ELLESDFLK--CSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESL 754
E K C+V +PF R+K+K F + F+ S S L + A S + ER +
Sbjct: 882 VNEERRLQKQVCNVSYPFFRAKAKVAFRLDFEFSK-SIFLHHLEIELAAGSDSNERDSTK 940
Query: 755 HDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYN 814
DN L L +E D T +S + E ++ + D + P + ++ N
Sbjct: 941 EDNVAPLRFHLKYEADVLFT---RSSSLSHYEVKPNSSLERYDGIG---PPFSCIFRIQN 994
Query: 815 TGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIF 874
G + G + I+ P SG + +++ + + +C+ N T +E++
Sbjct: 995 LGLFPIHGMMMKITIPIATRSGN-RLLKLRDFLTDEANTSCNIWGNSTEYRPTPVEEDL- 1052
Query: 875 HTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSV 934
R+ ++ +CN + +E I+ ++L N L S
Sbjct: 1053 -----------RRAPQLNHSNSDVVSINCNIRLVPNQE---INFHLLGN---LWLRSLKA 1095
Query: 935 IQFMSRAKVKVDPALR----VVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVG 990
+++ S K+ V+ AL+ I +VFE + + V WII S L G
Sbjct: 1096 LKYKS-MKIMVNAALQRQFHSPFIFREEDPSRQIVFEI--SKQEDWQVPIWIIVGSTLGG 1152
Query: 991 ILIFLLLAVLLWKMGFFR--RRYKE 1013
+L+ LL + LWK+GFFR RR +E
Sbjct: 1153 LLLLALLVLALWKLGFFRSARRRRE 1177
Score = 64.3 bits (155), Expect = 6e-10
Identities = 53/175 (30%), Positives = 83/175 (47%), Gaps = 29/175 (16%)
Query: 14 RALLLALVVAGIPA--GAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKAD 71
R L++A ++ P +N+D ++P G +FFGY V +H +W++VGAP
Sbjct: 5 RGLVVAWALSLWPGFTDTFNMDTRKPRVIPGSRTAFFGYTVQQHDISGNKWLVVGAPLET 64
Query: 72 SKYSPSVKSPGAVFKCRV-HTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLA 130
+ Y + G V+KC V H N CT+L++ R S E +D+ +G+SLA
Sbjct: 65 NGY----QKTGDVYKCPVIHGN----CTKLNLGRVTLSNVS------ERKDNMRLGLSLA 110
Query: 131 RQPKADGRVLACAHRWK----NIYYEADHILPHGFCYIIPSNLQAKGRTLIPCYE 181
PK D LAC+ W + YY G C + SN + +T+ P +
Sbjct: 111 TNPK-DNSFLACSPLWSHECGSSYYTT------GMCSRVNSNFRF-SKTVAPALQ 157
>gi|223468595 integrin alpha-V isoform 2 [Homo sapiens]
Length = 1002
Score = 249 bits (637), Expect = 7e-66
Identities = 264/1041 (25%), Positives = 462/1041 (44%), Gaps = 132/1041 (12%)
Query: 62 WVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRD 121
++LVGAPKA++ P + G V KC + RRC ++ NR + E +
Sbjct: 19 FLLVGAPKANTT-QPGIVEGGQVLKC--DWSSTRRCQPIEFDATGNRDYAKDDPL-EFKS 74
Query: 122 DEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPC 179
+W G S+ + K D ++LACA + W+ + P G C++ K PC
Sbjct: 75 HQWFGASV--RSKQD-KILACAPLYHWRTEMKQERE--PVGTCFLQDGT---KTVEYAPC 126
Query: 180 YEEYKKKYGEEHGSCQAGIAGFFTE-ELVVMGAPGSFYWAGTI------KVLNLTD-NTY 231
+ G+ G CQ G + FT+ + V++G PGSFYW G + ++++ D N Y
Sbjct: 127 RSQDIDADGQ--GFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVY 184
Query: 232 -LKLNDEVIMNRRY-----TYLGYAVTAGHFSHPSTIDVVGGAPQD-KGIGKVYIFRADR 284
+K N+++ +YLGY+V G F+ D V G P+ + +G VYI+
Sbjct: 185 SIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKN 244
Query: 285 RSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSE------IRDEGQVT 338
S ++ +G++M +YFG S+ A D+NGD +D+ +GAP+F + +++ GQV+
Sbjct: 245 MSS----LYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVS 300
Query: 339 VYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE-DDFAGAVY 397
V + R +G + L G + A FG +IA L DLD DGF D+AI AP +D G VY
Sbjct: 301 VSLQRASGDFQTT-KLNGFEVF-ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVY 358
Query: 398 IYHGDAGGIVPQYSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVL 456
I++G + G+ S L GQ + FG S+ G D+D NGYPD+ VGAF D +L
Sbjct: 359 IFNGRSTGLNAVPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAIL 418
Query: 457 LRARPVITVDVSI-FLPGSINITAPQCH--DGQQPVNCLNVTTCFSFHGKHV-PGEIGLN 512
RARPVITV+ + P +N C V+C NV C GK V P ++
Sbjct: 419 YRARPVITVNAGLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQ 478
Query: 513 YVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVK--RRVQDVI 570
L+ D K+KG + R F+ + + + C +A+++ +D +
Sbjct: 479 VELLLD-KLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQ-CEELIAYLRDESEFRDKL 536
Query: 571 SPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQ 630
+PI Y L + L P+L I+++ + DC D
Sbjct: 537 TPITIFMEYRLDYRTAA----DTTGLQPILNQFTPANISRQAHILL-------DCGEDNV 585
Query: 631 LQGKLLLS-SMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQK 689
+ KL +S D+K +Y +G ++L + N G+ AY+A + ++ + FI + +
Sbjct: 586 CKPKLEVSVDSDQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRN 643
Query: 690 EE--MGISCELLESDFLK---CSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQ 744
E +SC + + C +G P M++ ++ + F S + + F + Q
Sbjct: 644 NEALARLSCAFKTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQ 702
Query: 745 SGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQ 804
S N L D + + H+VD ++ + + G S F+ + + E
Sbjct: 703 SSN------LFDKVSPV---VSHKVDLAVLAAVE----IRGVSSPDHIFLPIPNWEHKEN 749
Query: 805 P---------INITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNC 855
P + ++ N GPS+ + + + +P + ++ ++ + + G
Sbjct: 750 PETEEDVGPVVQHIYELRNNGPSSFSKAMLHLQWPYKYNN-NTLLYILHYDIDGPMNCTS 808
Query: 856 SFQKNPTPCIIPQ--------------EQENIFHTIFAFFTKSGRKVLDCEKPGIS-CLT 900
+ NP I E++++ ++ L C G++ CL
Sbjct: 809 DMEINPLRIKISSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGC---GVAQCLK 865
Query: 901 AHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGN-- 958
C L + +S + + LL TE + + +K + V+E + N
Sbjct: 866 IVCQVGRLDRGKSAILYVKSLLWTETFMNKENQNHSY----SLKSSASFNVIEFPYKNLP 921
Query: 959 PEEVT----VVFEALHNLEPRGYVVG-WIIAISLLVGILIFLLLAVLLWKMGFFRR---- 1009
E++T V ++P V W+I +++L G+L+ +L ++++MGFF+R
Sbjct: 922 IEDITNSTLVTTNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPP 981
Query: 1010 ---RYKEIIEAEKNRKENEDS 1027
+ +E ++ +N + N ++
Sbjct: 982 QEEQEREQLQPHENGEGNSET 1002
>gi|88758615 integrin alpha 2b preproprotein [Homo sapiens]
Length = 1039
Score = 249 bits (636), Expect = 9e-66
Identities = 270/1075 (25%), Positives = 460/1075 (42%), Gaps = 127/1075 (11%)
Query: 16 LLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRW-VLVGAPKADSKY 74
LLL A PA A NLDP + + GP S FG+++ H + R ++VGAP+
Sbjct: 18 LLLLGPCAAPPAWALNLDPVQLTFYAGPNGSQFGFSLDFHKDSHGRVAIVVGAPRT---L 74
Query: 75 SPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPK 134
PS + G VF C + + L R + R +T + + + +G S+
Sbjct: 75 GPSQEETGGVFLCPWRAEGGQCPSLLFDLRDETRNVG-SQTLQTFKARQGLGASVVSWSD 133
Query: 135 ADGRVLACA--HRWKNIYYEADHI--LPHGFCYIIPSNL-------QAKGRTLIPCYEEY 183
++ACA W N+ + + P G C++ +G TL Y E
Sbjct: 134 V---IVACAPWQHW-NVLEKTEEAEKTPVGSCFLAQPESGRRAEYSPCRGNTLSRIYVEN 189
Query: 184 KKKYGEEHGSCQAGIAGFFTEE-LVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIM-- 240
+ + + C+AG + T+ +V+GAPG +Y+ G + + D + +++
Sbjct: 190 DFSWDKRY--CEAGFSSVVTQAGELVLGAPGGYYFLGLLAQAPVAD-IFSSYRPGILLWH 246
Query: 241 -----------NRRYT--YLGYAVTAGHFSHP-STIDVVGGAPQ-DKGIGKVYIFRADRR 285
N Y Y GY+V G F +T + V GAP +G V I + +
Sbjct: 247 VSSQSLSFDSSNPEYFDGYWGYSVAVGEFDGDLNTTEYVVGAPTWSWTLGAVEILDSYYQ 306
Query: 286 SGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSEIRDE------GQVTV 339
++ + G++M SYFG S+ D+NGDG DLLVGAP++ E R + G+V +
Sbjct: 307 -----RLHRLRGEQMASYFGHSVAVTDVNGDGRHDLLVGAPLYMESRADRKLAEVGRVYL 361
Query: 340 YIN-RGNGAL-EEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFA-GAV 396
++ RG AL L LTG Y FG +IA L DLD DG+ D+A+ AP G V
Sbjct: 362 FLQPRGPHALGAPSLLLTGTQLYG-RFGSAIAPLGDLDRDGYNDIAVAAPYGGPSGRGQV 420
Query: 397 YIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVL 456
++ G + G+ + S L P FG S+ G +D+D NGYPD+ VGA+ ++ V +
Sbjct: 421 LVFLGQSEGLRSRPSQVLDSPF--PTGSAFGFSLRGAVDIDDNGYPDLIVGAYGANQVAV 478
Query: 457 LRARPVITVDVSIFLPGSINITAPQC--HDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYV 514
RA+PV+ V + + S+N C + PV+C N+ C G ++P ++ LN
Sbjct: 479 YRAQPVVKASVQLLVQDSLNPAVKSCVLPQTKTPVSCFNIQMCVGATGHNIPQKLSLNAE 538
Query: 515 LMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEE-TCRHYVAHVKRRV--QDVIS 571
L D K +G+ +LLG T L L C +A ++ +D +S
Sbjct: 539 LQLDRQKPRQGRR----VLLLGSQQAGTTLNLDLGGKHSPICHTTMAFLRDEADFRDKLS 594
Query: 572 PIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSED-CAADLQ 630
PIV SL G + P + + ++ + V + C +D C LQ
Sbjct: 595 PIVLSLNVSLPPTEAG--------MAPAVVLHGDTHVQEQTRIVLD--CGEDDVCVPQLQ 644
Query: 631 LQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKE 690
L + S L +GA + L + +N G+ AY+A ++ ++ + ++
Sbjct: 645 LTASVTGSP-------LLVGADNVLELQMDAANEGEGAYEAELAVHLPQGAHYMRALSNV 697
Query: 691 E--MGISCELL---ESDFLKCSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQS 745
E + C E+ + C +G P M+ ++ +++ +L E +SF + +S
Sbjct: 698 EGFERLICNQKKENETRVVLCELGNP-MKKNAQIGIAMLVSVGNLEEAGESVSFQLQIRS 756
Query: 746 GNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQP 805
N++ S ++L VP+ E + G P S V + + L+
Sbjct: 757 KNSQNPNS---KIVLLDVPVRAEAQVELRGNSFPASLVVAAEEGER---EQNSLDSWGPK 810
Query: 806 INITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKG--NCSFQ----- 858
+ T +++N GP T+ G +SI P + S +++ ++ ++ Q +G C Q
Sbjct: 811 VEHTYELHNNGPGTVNGLHLSIHLPGQ--SQPSDLLYILDI---QPQGGLQCFPQPPVNP 865
Query: 859 ---------KNPTPCIIPQEQENIFHTIFAFFTKSGRKVLD-----CEKPGISCLTAHCN 904
+P+P I P + IF + ++ D C+ C C+
Sbjct: 866 LKVDWGLPIPSPSP-IHPAHHKRDRRQIFLPEPEQPSRLQDPVLVSCD--SAPCTVVQCD 922
Query: 905 FSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVTV 964
+A+ + + + L L + S A V V E V
Sbjct: 923 LQEMARGQRAMVTVLAFLWLPSLYQRPLDQFVLQSHAWFNVSSLPYAVPPLSLPRGEAQV 982
Query: 965 VFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEK 1019
+ L LE R + W++ + +L G+L+ +L + +WK+GFF+R + E ++
Sbjct: 983 WTQLLRALEERAIPIWWVL-VGVLGGLLLLTILVLAMWKVGFFKRNRPPLEEDDE 1036
>gi|31657142 integrin, alpha 1 precursor [Homo sapiens]
Length = 1179
Score = 246 bits (627), Expect = 1e-64
Identities = 237/861 (27%), Positives = 379/861 (44%), Gaps = 100/861 (11%)
Query: 195 QAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTD-----NTYLKLNDEVIMNRRYTYLGY 249
Q G + ++++ V++GA G++ W GT+ + + NT + +YLGY
Sbjct: 379 QTGFSAHYSQDWVMLGAVGAYDWNGTVVMQKASQIIIPRNTTFNVESTKKNEPLASYLGY 438
Query: 250 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQA-SGKKMGSYFGSSL 308
V + S + + G P+ G+V I+R + + IKI Q SG+++GSYFGS L
Sbjct: 439 TVNSATASSGDVL-YIAGQPRYNHTGQVIIYRMEDGN---IKILQTLSGEQIGSYFGSIL 494
Query: 309 CAVDLNGDGLSD-LLVGAPMFSEIRDEGQVTVYINRGNGA-LEEQLAL------------ 354
D++ D +D LLVGAPM+ E Q VY+ N E Q++L
Sbjct: 495 TTTDIDKDSNTDILLVGAPMYMGTEKEEQGKVYVYALNQTRFEYQMSLEPIKQTCCSSRQ 554
Query: 355 -------TGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIV 407
+ A FG +IA++ DL+ DGF D+ IGAP EDD GAVYIYHG I
Sbjct: 555 HNSCTTENKNEPCGARFGTAIAAVKDLNLDGFNDIVIGAPLEDDHGGAVYIYHGSGKTIR 614
Query: 408 PQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDV 467
+Y+ ++ L+ FGQSI G +D++G+G DVT+G L +R V V V
Sbjct: 615 KEYAQRIPSGGDGKTLKFFGQSIHGEMDLNGDGLTDVTIGGL--GGAALFWSRDVAVVKV 672
Query: 468 SI-FLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPG---EIGLNYVLMADVAKKE 523
++ F P +NI CH + C+N T CF K E L Y + D +
Sbjct: 673 TMNFEPNKVNIQKKNCHMEGKETVCINATVCFDVKLKSKEDTIYEADLQYRVTLDSLR-- 730
Query: 524 KGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSE 583
Q+ R +F G +V + + E T + K QD S
Sbjct: 731 --QISRSFF--SGTQERKVQRNITVRKSECTKHSFYMLDKHDFQD-------------SV 773
Query: 584 HVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNC-RSEDCAADLQLQGKLLLSSMDE 642
+T + P PVL + + F ++C E C +DL L + E
Sbjct: 774 RITLDFNLTDPENGPVLDDSLPNSVHE--YIPFAKDCGNKEKCISDLSLH-----VATTE 826
Query: 643 KTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFF--INMWQKEEMGISCELLE 700
K L + ++++++ N D AY+ + S L F I QK+ SCE
Sbjct: 827 KDLLIVRSQNDKFNVSLTVKNTKDSAYNTRTIVHYSPNLVFSGIEAIQKD----SCE--S 880
Query: 701 SDFLKCSVGFPFMRSKSKYEFSVI--FDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNT 758
+ + C VG+PF+R F ++ F+TS+L E ++ ++A S + E E+L DN
Sbjct: 881 NHNITCKVGYPFLRRGEMVTFKILFQFNTSYLM---ENVTIYLSATSDSEEPPETLSDNV 937
Query: 759 LVLMVPLMHEVDTSITGIMSP--TSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTG 816
+ + +P+ +EV S S E+V ++ E INI + +G
Sbjct: 938 VNISIPVKYEVGLQFYSSASEYHISIAANETVPEV----INSTEDIGNEINIFYLIRKSG 993
Query: 817 PSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHT 876
+P +SISFPN S+G ++ + E NC P I ++ T
Sbjct: 994 SFPMPELKLSISFPNMTSNGYPVLYPTG--LSSSENANCRPHIFEDPFSINSGKK---MT 1048
Query: 877 IFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQ 936
K G +LDC + +T CN L + +++ ++L K S +
Sbjct: 1049 TSTDHLKRG-TILDCNTCKFATIT--CN---LTSSDISQVNVSLILWKPTFIKSYFSSLN 1102
Query: 937 FMSRAKVKVDPALRVVEIAHGNPE-EVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFL 995
R +++ + A V+ ++ E + + + L G V W+I +S G+L+ +
Sbjct: 1103 LTIRGELRSENASLVLSSSNQKRELAIQISKDGL-----PGRVPLWVILLSAFAGLLLLM 1157
Query: 996 LLAVLLWKMGFFRRRYKEIIE 1016
LL + LWK+GFF+R K+ +E
Sbjct: 1158 LLILALWKIGFFKRPLKKKME 1178
Score = 50.8 bits (120), Expect = 6e-06
Identities = 33/127 (25%), Positives = 61/127 (48%), Gaps = 15/127 (11%)
Query: 29 AYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCR 88
++N+D + + F GP + FGY V ++ ++ +WVL+G+P + + G V+KC
Sbjct: 28 SFNVDVKNSMTFSGPVEDMFGYTVQQYENEEGKWVLIGSPLVGQPKNRT----GDVYKCP 83
Query: 89 VHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLAC----AH 144
V C +LD+ + E +++ G +L P +G LAC A+
Sbjct: 84 VGRGESLPCVKLDLPVNTSI-----PNVTEVKENMTFGSTLVTNP--NGGFLACGPLYAY 136
Query: 145 RWKNIYY 151
R +++Y
Sbjct: 137 RCGHLHY 143
>gi|223468597 integrin alpha-V isoform 3 precursor [Homo sapiens]
Length = 1012
Score = 240 bits (612), Expect = 6e-63
Identities = 274/1090 (25%), Positives = 476/1090 (43%), Gaps = 151/1090 (13%)
Query: 7 PRGAGRLRALLLALVVAGIP---AGAYNLDPQRPVHFQGPADSFFGYAVLEHF---HDNT 60
PR RL L L+++G+ A+NLD P + GP S+FG+AV + F +
Sbjct: 5 PRRRLRLGPRGLPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAV-DFFVPSASSR 63
Query: 61 RWVLVGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDR 120
++LVGAPKA++ P + G V KC + RRC ++ NR + E +
Sbjct: 64 MFLLVGAPKANTT-QPGIVEGGQVLKC--DWSSTRRCQPIEFDATGNRDYAKDDPL-EFK 119
Query: 121 DDEWMGVSLARQPKADGRVLACA--HRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIP 178
+W G S+ + K D ++LACA + W+ + P G C+ LQ +T+
Sbjct: 120 SHQWFGASV--RSKQD-KILACAPLYHWRTEMKQERE--PVGTCF-----LQDGTKTV-- 167
Query: 179 CYEEYKKKYGEEHGSCQAG-IAGFFTEELVVMGAPGSFYWAGTIKVLN-LTDNTYLKLND 236
E+ C++ + E+V P + +IK N L T + D
Sbjct: 168 -----------EYAPCRSRQLISDQVAEIVSKYDPNVY----SIKYNNQLATRTAQAIFD 212
Query: 237 EVIMNRRYTYLGYAVTAGHFSHPSTIDVVGGAPQD-KGIGKVYIFRADRRSGTLIKIFQA 295
+ +YLGY+V G F+ D V G P+ + +G VYI+ S ++
Sbjct: 213 D-------SYLGYSVAVGDFNGDGIDDFVSGVPRAARTLGMVYIYDGKNMSS----LYNF 261
Query: 296 SGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFSE------IRDEGQVTVYINRGNGALE 349
+G++M +YFG S+ A D+NGD +D+ +GAP+F + +++ GQV+V + R +G +
Sbjct: 262 TGEQMAAYFGFSVAATDINGDDYADVFIGAPLFMDRGSDGKLQEVGQVSVSLQRASGDFQ 321
Query: 350 EQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE-DDFAGAVYIYHGDAGGIVP 408
L G + A FG +IA L DLD DGF D+AI AP +D G VYI++G + G+
Sbjct: 322 TT-KLNGFEVF-ARFGSAIAPLGDLDQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNA 379
Query: 409 QYSMKLSGQ-KINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDV 467
S L GQ + FG S+ G D+D NGYPD+ VGAF D +L RARPVITV+
Sbjct: 380 VPSQILEGQWAARSMPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNA 439
Query: 468 SI-FLPGSINITAPQCH--DGQQPVNCLNVTTCFSFHGKHV-PGEIGLNYVLMADVAKKE 523
+ P +N C V+C NV C GK V P ++ L+ D K+
Sbjct: 440 GLEVYPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLLD-KLKQ 498
Query: 524 KGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVK--RRVQDVISPIVFEAAYSL 581
KG + R F+ + + + C +A+++ +D ++PI Y L
Sbjct: 499 KGAIRRALFLYSRSPSHSKNMTISRGGLMQ-CEELIAYLRDESEFRDKLTPITIFMEYRL 557
Query: 582 SEHVTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLS-SM 640
+ L P+L I+++ + DC D + KL +S
Sbjct: 558 DYRTAA----DTTGLQPILNQFTPANISRQAHILL-------DCGEDNVCKPKLEVSVDS 606
Query: 641 DEKTLYLALGAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEE--MGISCEL 698
D+K +Y +G ++L + N G+ AY+A + ++ + FI + + E +SC
Sbjct: 607 DQKKIY--IGDDNPLTLIVKAQNQGEGAYEAELIVSIPLQADFIGVVRNNEALARLSCAF 664
Query: 699 LESDFLK---CSVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLH 755
+ + C +G P M++ ++ + F S + + F + QS N L
Sbjct: 665 KTENQTRQVVCDLGNP-MKAGTQLLAGLRFSVHQQSEMDTSVKFDLQIQSSN------LF 717
Query: 756 DNTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQP---------I 806
D + + H+VD ++ + + G S F+ + + E P +
Sbjct: 718 DKVSPV---VSHKVDLAVLAAVE----IRGVSSPDHIFLPIPNWEHKENPETEEDVGPVV 770
Query: 807 NITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCII 866
++ N GPS+ + + + +P + ++ ++ + + G + NP I
Sbjct: 771 QHIYELRNNGPSSFSKAMLHLQWPYKYNN-NTLLYILHYDIDGPMNCTSDMEINPLRIKI 829
Query: 867 PQ--------------EQENIFHTIFAFFTKSGRKVLDCEKPGIS-CLTAHCNFSALAKE 911
E++++ ++ L C G++ CL C L +
Sbjct: 830 SSLQTTEKNDTVAGQGERDHLITKRDLALSEGDIHTLGC---GVAQCLKIVCQVGRLDRG 886
Query: 912 ESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGN--PEEVT----VV 965
+S + + LL TE + + +K + V+E + N E++T V
Sbjct: 887 KSAILYVKSLLWTETFMNKENQNHSY----SLKSSASFNVIEFPYKNLPIEDITNSTLVT 942
Query: 966 FEALHNLEPRGYVVG-WIIAISLLVGILIFLLLAVLLWKMGFFRR-------RYKEIIEA 1017
++P V W+I +++L G+L+ +L ++++MGFF+R + +E ++
Sbjct: 943 TNVTWGIQPAPMPVPVWVIILAVLAGLLLLAVLVFVMYRMGFFKRVRPPQEEQEREQLQP 1002
Query: 1018 EKNRKENEDS 1027
+N + N ++
Sbjct: 1003 HENGEGNSET 1012
>gi|38569398 integrin, alpha 10 precursor [Homo sapiens]
Length = 1167
Score = 235 bits (600), Expect = 1e-61
Identities = 214/844 (25%), Positives = 374/844 (44%), Gaps = 71/844 (8%)
Query: 200 GFFTEEL---VVMGAPGSFYWAGTIKVLNLTDNTY---LKLNDEV--IMNRRYTYLGYAV 251
GF T L ++ G G++ W G++ L + + L DE + YLGY+V
Sbjct: 376 GFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSV 435
Query: 252 TAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAV 311
++ + + GAP+ + GKV F+ ++ G + G+++GSYFGS LC +
Sbjct: 436 SSMLLRGGRRL-FLSGAPRFRHRGKVIAFQL-KKDGAVRVAQSLQGEQIGSYFGSELCPL 493
Query: 312 DLNGDGLSD-LLVGAPMF--SEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESI 368
D + DG +D LLV APMF + ++ G+V VY+ L Q L + +A FG ++
Sbjct: 494 DTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPEPPQDARFGFAM 553
Query: 369 ASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQ 428
+L DL+ DGF DVA+GAP ED GA+Y+YHG G+ P + +++ + L FG+
Sbjct: 554 GALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGR 613
Query: 429 SISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQCHDGQQ 487
S+ G +D+DG+ DV VGA + +LL +RP++ + S+ P +I++ C Q
Sbjct: 614 SVDGRLDLDGDDLVDVAVGA--QGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQ 671
Query: 488 PVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTEKLQ 547
CL CF + PG + + + E R F G+ + +L+
Sbjct: 672 EAVCLTAALCFQVTSR-TPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLS--PRRLR 728
Query: 548 LTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQK 607
L+ TC HV D + P+ ++L PVL +G
Sbjct: 729 LSVGNVTCEQLHFHV-LDTSDYLRPVALTVTFALDNTTKP---------GPVL--NEGSP 776
Query: 608 IAQKNQTVFERNCRSE-DCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGD 666
+ + F ++C + +C DL LQ + + K ++ G + + ++ ++ N +
Sbjct: 777 TSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRG-SRKAPFVVRGGRRKVLVSTTLENRKE 835
Query: 667 DAYDANVSFNVSRELFFINMWQKEE--MGISCELLESDFLKCSVGFPFMRSKSKYEFSVI 724
+AY+ ++S SR L ++ + E + + C + CSVG P ++ +K F +
Sbjct: 836 NAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLE 895
Query: 725 FDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVY 784
F+ S S +V +TA S + ER+ +L DNT + +E + S S ++
Sbjct: 896 FEFSCSSLLSQVF-VKLTASSDSLERNGTLQDNTAQTSAYIQYEPHL----LFSSESTLH 950
Query: 785 GESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQ 844
V + + TL+V N G + G +S P ++ GG +
Sbjct: 951 RYEVHPYGTLPVGP----GPEFKTTLRVQNLGCYVVSGLIISALLP-AVAHGGNYFLSLS 1005
Query: 845 EMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCN 904
+++ +C Q P P E + HT C C+
Sbjct: 1006 QVIT--NNASCIVQNLTEPPGPPVHPEELQHT------------NRLNGSNTQCQVVRCH 1051
Query: 905 FSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVD--PALRVVEIAHGNPEEV 962
LAK ++ + L++ E ++ + +S ++ + L++ E + + +
Sbjct: 1052 LGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLL 1111
Query: 963 TVVFEALHNLEPRGYVVG-WIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNR 1021
VV + R ++ WI+ S+L G+L+ LL LWK+GFF +K+I E EK
Sbjct: 1112 EVV-------QTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFF--AHKKIPEEEKRE 1162
Query: 1022 KENE 1025
++ E
Sbjct: 1163 EKLE 1166
Score = 58.9 bits (141), Expect = 2e-08
Identities = 47/158 (29%), Positives = 68/158 (43%), Gaps = 13/158 (8%)
Query: 16 LLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYS 75
L L LV +NLD P F GP ++ FGY+VL+H RW+LVGAP
Sbjct: 9 LFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWD----G 64
Query: 76 PSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKA 135
PS G V++C V + C A+G G + + +G+SL +
Sbjct: 65 PSGDRRGDVYRCPVGGAHNAPC-----AKGHLGDYQLGNS-SHPAVNMHLGMSLL-ETDG 117
Query: 136 DGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKG 173
DG +ACA W + G C + ++ Q +G
Sbjct: 118 DGGFMACAPLWSRAC--GSSVFSSGICARVDASFQPQG 153
>gi|34452173 integrin alpha X precursor [Homo sapiens]
Length = 1163
Score = 216 bits (550), Expect = 9e-56
Identities = 230/858 (26%), Positives = 397/858 (46%), Gaps = 104/858 (12%)
Query: 195 QAGIAGFFTEELVVMGAPGSFYWAGTIKVL--NLTDNTYLKLNDEVIMNRRYTYLGYAVT 252
Q G + FT + V+GA GSF W+G + N++ T++ ++ E + + R +YLGY+
Sbjct: 353 QEGFSAVFTPDGPVLGAVGSFTWSGGAFLYPPNMSP-TFINMSQENV-DMRDSYLGYSTE 410
Query: 253 AGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVD 312
+ ++ V GAP+ + GK IF R + + +G ++GSYFG+SLC+VD
Sbjct: 411 LALWKGVQSL--VLGAPRYQHTGKAVIFTQVSRQWRMKA--EVTGTQIGSYFGASLCSVD 466
Query: 313 LNGDGLSDL-LVGAPMFSEIRDEGQVTVY-INRGNGALEEQLALTGDGAYN-AHFGESIA 369
++ DG +DL L+GAP + E GQV+V + RG L G+ + FG ++
Sbjct: 467 VDSDGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGWRRWWCDAVLYGEQGHPWGRFGAALT 526
Query: 370 SLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAG-GIVPQYSMKLSGQKINPVLRMFGQ 428
L D++ D DV IGAP E++ GAVY++HG G I P +S +++G +++ L+ FGQ
Sbjct: 527 VLGDVNGDKLTDVVIGAPGEEENRGAVYLFHGVLGPSISPSHSQRIAGSQLSSRLQYFGQ 586
Query: 429 SISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQCHD--- 484
++SGG D+ +G D+ VGA V+LLR RPV+ V VS+ F+P I +A +C +
Sbjct: 587 ALSGGQDLTQDGLVDLAVGA--RGQVLLLRTRPVLWVGVSMQFIPAEIPRSAFECREQVV 644
Query: 485 GQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQVTE 544
+Q + N+ K++ G L + D+A PR F ET +
Sbjct: 645 SEQTLVQSNICLYIDKRSKNLLGSRDLQSSVTLDLALDPGRLSPRATF---QETKNRSLS 701
Query: 545 KLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKK 604
++++ ++ C ++ + V+D ++PI ++L G+ L P+L
Sbjct: 702 RVRVLGLKAHCENFNLLLPSCVEDSVTPITLRLNFTL----VGKPLLAFRNLRPML---- 753
Query: 605 GQKIAQKNQTV---FERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISI 661
AQ+ T FE+N C AD Q L +S L +G+ ++ + +
Sbjct: 754 -AADAQRYFTASLPFEKN-----CGADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMV 807
Query: 662 SNLGDDAYDANVSFNVSRELFFINMWQKEEMG------ISCELLE-----SDFLKCSVGF 710
N G+D+Y ++F+ L + + + ++ G ++C+ + C +
Sbjct: 808 WNDGEDSYGTTITFSHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINH 867
Query: 711 PFMRSKSKYEFSVIFDTS--HLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHE 768
R ++ F FD S + G+ +L+ V++++ NT R+ T L +P+ +
Sbjct: 868 LIFRGGAQITFLATFDVSPKAVLGDRLLLTANVSSEN-NTPRTSK---TTFQLELPVKYA 923
Query: 769 VDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSIS 828
V T ++ T ++ NF + ++ E H QV N G LP VSI+
Sbjct: 924 VYTVVSSHEQFTKYL--------NFSESEEKESHVAMHR--YQVNNLGQRDLP---VSIN 970
Query: 829 F--PNRLSSGG----AEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFT 882
F P L+ E+ H Q + CS +K I P + + H
Sbjct: 971 FWVPVELNQEAVWMDVEVSHPQNPSL-----RCSSEK-----IAPPASDFLAHI------ 1014
Query: 883 KSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAK 942
VLDC G CL C+ + + +E + L+ +++ + +S A+
Sbjct: 1015 -QKNPVLDCSIAG--CLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQKKVSVVSVAE 1071
Query: 943 VKVDPALRVVEIAHGNP----EEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLA 998
+ D + V G + T V E P +VG S + G+L+ L+
Sbjct: 1072 ITFDTS--VYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVG-----SSIGGLLLLALIT 1124
Query: 999 VLLWKMGFFRRRYKEIIE 1016
+L+K+GFF+R+YKE++E
Sbjct: 1125 AVLYKVGFFKRQYKEMME 1142
>gi|116295258 integrin alpha 2 precursor [Homo sapiens]
Length = 1181
Score = 216 bits (549), Expect = 1e-55
Identities = 210/838 (25%), Positives = 406/838 (48%), Gaps = 91/838 (10%)
Query: 205 ELVVMGAPGSFYWAGTIKVLNLTDNTYL----KLNDEVIMNRRYT-YLGYAVTAGHFSHP 259
+++++GA G+F W+GTI + T + +L + D+++ +R ++ YLGY+V A S
Sbjct: 392 DILMLGAVGAFGWSGTI--VQKTSHGHLIFPKQAFDQILQDRNHSSYLGYSVAA--ISTG 447
Query: 260 STIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLS 319
+ V GAP+ G++ ++ + +G + I G ++GSYFGS LC+VD++ D ++
Sbjct: 448 ESTHFVAGAPRANYTGQIVLYSVNE-NGNITVIQAHRGDQIGSYFGSVLCSVDVDKDTIT 506
Query: 320 D-LLVGAPMF-SEIR-DEGQVTVYINRGNGALEEQLALTG-DGAYNAHFGESIASLDDLD 375
D LLVGAPM+ S+++ +EG+V ++ + G L + L G +G N FG +IA+L D++
Sbjct: 507 DVLLVGAPMYMSDLKKEEGRVYLFTIK-EGILGQHQFLEGPEGIENTRFGSAIAALSDIN 565
Query: 376 NDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQ--KINPVLRMFGQSISGG 433
DGF DV +G+P E+ +GAVYIY+G G I +YS K+ G L+ FG+S+ G
Sbjct: 566 MDGFNDVIVGSPLENQNSGAVYIYNGHQGTIRTKYSQKILGSDGAFRSHLQYFGRSLDGY 625
Query: 434 IDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDV-SIFLPGSINITAPQCHDGQQPVNCL 492
D++G+ DV++GAF VV L ++ + V + + F P I + +
Sbjct: 626 GDLNGDSITDVSIGAF--GQVVQLWSQSIADVAIEASFTPEKITLVNKNAQ--------I 675
Query: 493 NVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYF-VLLGETMGQVTEKLQLTYM 551
+ CFS K P + ++ ++ G RV L E + +K +
Sbjct: 676 ILKLCFS--AKFRPTKQNNQVAIVYNITLDADGFSSRVTSRGLFKENNERCLQKNMVVNQ 733
Query: 552 EETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLRWKKGQKIAQK 611
++C ++ ++ + DV++ + SL E P +P L + + A+
Sbjct: 734 AQSCPEHIIYI-QEPSDVVNSLDLRVDISL----------ENPGTSPAL--EAYSETAKV 780
Query: 612 NQTVFERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYD 670
F ++C + C +DL L + + ++ ++ ++ K ++ ++++ N + AY+
Sbjct: 781 FSIPFHKDCGEDGLCISDLVLDVRQIPAAQEQP--FIVSNQNKRLTFSVTLKNKRESAYN 838
Query: 671 ANVSFNVSRELFFINM-WQKEEMGISCELLESD-FLKCSVGFPFMRSKSKYEFSVIFDTS 728
+ + S LFF + + ++C++ S + C VG+P ++ + + F++ FD +
Sbjct: 839 TGIVVDFSENLFFASFSLPVDGTEVTCQVAASQKSVACDVGYPALKREQQVTFTINFDFN 898
Query: 729 HLSGEEEV-LSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSFVYGES 787
+ + + LSF ++S + E+ DN + L +PL+++ + +T + +
Sbjct: 899 LQNLQNQASLSFQALSES----QEENKADNLVNLKIPLLYDAEIHLTRSTNINFYEISSD 954
Query: 788 VDAANFI-QLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQEM 846
+ + + +D+ F +L+V TG + ++V I P M+
Sbjct: 955 GNVPSIVHSFEDVGPKF---IFSLKV-TTGSVPVSMATVIIHIPQYTKEKNPLMYLTG-- 1008
Query: 847 VVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHC-NF 905
V + G+ S + P I Q ++ +F +++ R + ++C TA C N
Sbjct: 1009 VQTDKAGDISCNADINPLKIGQTSSSV-----SFKSENFRHTKE-----LNCRTASCSNV 1058
Query: 906 SALAKEESRTIDIYMLLNTEI----LKKDSSSVIQFMSRAKVKV-DPALRVVEIAHGNPE 960
+ K+ + ++ + T I + +Q + A++ +P + V+E
Sbjct: 1059 TCWLKDVHMKGEYFVNVTTRIWNGTFASSTFQTVQLTAAAEINTYNPEIYVIE-----DN 1113
Query: 961 EVTVVFEALHNLE----PRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEI 1014
VT+ + E P G ++G IIA GIL+ L L +LWK+GFF+R+Y+++
Sbjct: 1114 TVTIPLMIMKPDEKAEVPTGVIIGSIIA-----GILLLLALVAILWKLGFFKRKYEKM 1166
Score = 39.3 bits (90), Expect = 0.019
Identities = 41/149 (27%), Positives = 63/149 (42%), Gaps = 17/149 (11%)
Query: 9 GAGRLRALLLALVVAGIP--AGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVG 66
GA L LL+ + GI AYN+ F GP+ FGYAV + + W+LVG
Sbjct: 7 GAAPLPLLLVLALSQGILNCCLAYNVGLPEAKIFSGPSSEQFGYAVQQFINPKGNWLLVG 66
Query: 67 APKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMG 126
+P + + G V+KC V + C +L++ + ++ E + + +G
Sbjct: 67 SPWSGFPEN----RMGDVYKCPVDLS-TATCEKLNL-----QTSTSIPNVTEMKTNMSLG 116
Query: 127 VSLARQPKADGRVLACAHRWK----NIYY 151
+ L R G L C W N YY
Sbjct: 117 LILTRN-MGTGGFLTCGPLWAQQCGNQYY 144
>gi|167466217 integrin alpha L isoform b precursor [Homo sapiens]
Length = 1086
Score = 216 bits (549), Expect = 1e-55
Identities = 186/615 (30%), Positives = 303/615 (49%), Gaps = 57/615 (9%)
Query: 196 AGIAGFFTEELVVMGAPGSFYWAGTIKVL--NLTDNTYLKLNDEVIMNRRYTYLGYAVTA 253
+GI+ + V+GA G+ WAG L +L D+T++ N+ + R YLGY VT
Sbjct: 269 SGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIG-NEPLTPEVRAGYLGYTVTW 327
Query: 254 GHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDL 313
S T + GAP+ + +G+V +F+ + G ++ G ++GSYFG LC VD+
Sbjct: 328 LP-SRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDV 386
Query: 314 NGDGLSDLL-VGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYN-AHFGESIASL 371
+ DG ++LL +GAP+F + G+V +Y R G EE L GD Y FGE+I +L
Sbjct: 387 DQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLG-FEEVSELQGDPGYPLGRFGEAITAL 445
Query: 372 DDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSIS 431
D++ DG DVA+GAP E+ GAVYI++G GG+ PQ S ++ G ++ ++ FG+SI
Sbjct: 446 TDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIH 503
Query: 432 GGIDMDGNGYPDVTVGAFMSDSVVLLRARPVI-TVDVSIFLPGSINITAPQC--HDGQQP 488
G D++G+G DV VGA +++L +RPV+ V + F P I + +C +
Sbjct: 504 GVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKM 561
Query: 489 VNCLNVTTCF-------SFHGKHVPGEIGLNYVLMADVAK-KEKGQMPRVYFVLLGETMG 540
+N+T CF F G+ V L Y L D + + +G P
Sbjct: 562 KEGVNITICFQIKSLIPQFQGRLV---ANLTYTLQLDGHRTRRRGLFP--------GGRH 610
Query: 541 QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSL-SEHVTGEEERELPPLTPV 599
++ + +T +C + H VQD+ISPI +SL E T ++R + P+
Sbjct: 611 ELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAGKDIPPI 669
Query: 600 LRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNI 659
LR ++ + FE+N C D + + L +S ++ L L A ++S+ +
Sbjct: 670 LR---PSLHSETWEIPFEKN-----CGEDKKCEANLRVSFSPARSRALRLTAFASLSVEL 721
Query: 660 SISNLGDDAYDANVSFNVSRELFF--INMWQ-KEEMGISCELLE------SDFLKCSVGF 710
S+SNL +DAY + + L F + M + ++ +SCE L S L C+V
Sbjct: 722 SLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALSCNVSS 781
Query: 711 PFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHE 768
P ++ ++F+T S G+ L VT N E S+ L DN+ ++P+++
Sbjct: 782 PIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC---NNEDSDLLEDNSATTIIPILYP 838
Query: 769 VDTSITGIMSPTSFV 783
++ I T +V
Sbjct: 839 INILIQDQEDSTLYV 853
Score = 36.6 bits (83), Expect = 0.13
Identities = 15/37 (40%), Positives = 28/37 (75%)
Query: 981 WIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEA 1017
++ +S + G+L+ LL+ ++L+K+GFF+R KE +EA
Sbjct: 1007 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1043
>gi|167466215 integrin alpha L isoform a precursor [Homo sapiens]
Length = 1170
Score = 213 bits (542), Expect = 8e-55
Identities = 188/620 (30%), Positives = 305/620 (49%), Gaps = 66/620 (10%)
Query: 196 AGIAGFFTEELVVMGAPGSFYWAGTIKVL--NLTDNTYLKLNDEVIMNRRYTYLGYAVTA 253
+GI+ + V+GA G+ WAG L +L D+T++ N+ + R YLGY VT
Sbjct: 352 SGISADLSRGHAVVGAVGAKDWAGGFLDLKADLQDDTFIG-NEPLTPEVRAGYLGYTVTW 410
Query: 254 GHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDL 313
S T + GAP+ + +G+V +F+ + G ++ G ++GSYFG LC VD+
Sbjct: 411 LP-SRQKTSLLASGAPRYQHMGRVLLFQEPQGGGHWSQVQTIHGTQIGSYFGGELCGVDV 469
Query: 314 NGDGLSDLL-VGAPMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYN-AHFGESIASL 371
+ DG ++LL +GAP+F + G+V +Y R G EE L GD Y FGE+I +L
Sbjct: 470 DQDGETELLLIGAPLFYGEQRGGRVFIYQRRQLG-FEEVSELQGDPGYPLGRFGEAITAL 528
Query: 372 DDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSIS 431
D++ DG DVA+GAP E+ GAVYI++G GG+ PQ S ++ G ++ ++ FG+SI
Sbjct: 529 TDINGDGLVDVAVGAPLEEQ--GAVYIFNGRHGGLSPQPSQRIEGTQVLSGIQWFGRSIH 586
Query: 432 GGIDMDGNGYPDVTVGAFMSDSVVLLRARPVI-TVDVSIFLPGSINITAPQC--HDGQQP 488
G D++G+G DV VGA +++L +RPV+ V + F P I + +C +
Sbjct: 587 GVKDLEGDGLADVAVGA--ESQMIVLSSRPVVDMVTLMSFSPAEIPVHEVECSYSTSNKM 644
Query: 489 VNCLNVTTCF-------SFHGKHVPGEIGLNYVLMADVAK-KEKGQMPRVYFVLLGETMG 540
+N+T CF F G+ V L Y L D + + +G P
Sbjct: 645 KEGVNITICFQIKSLIPQFQGRLV---ANLTYTLQLDGHRTRRRGLFP--------GGRH 693
Query: 541 QVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSL-SEHVTGEEER----ELPP 595
++ + +T +C + H VQD+ISPI +SL E T ++R ++PP
Sbjct: 694 ELRRNIAVT-TSMSCTDFSFHFPVCVQDLISPINVSLNFSLWEEEGTPRDQRAQGKDIPP 752
Query: 596 -LTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKN 654
L P L ++ + FE+N C D + + L +S ++ L L A +
Sbjct: 753 ILRPSLH-------SETWEIPFEKN-----CGEDKKCEANLRVSFSPARSRALRLTAFAS 800
Query: 655 ISLNISISNLGDDAYDANVSFNVSRELFF--INMWQ-KEEMGISCELLE------SDFLK 705
+S+ +S+SNL +DAY + + L F + M + ++ +SCE L S L
Sbjct: 801 LSVELSLSNLEEDAYWVQLDLHFPPGLSFRKVEMLKPHSQIPVSCEELPEESRLLSRALS 860
Query: 706 CSVGFPFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDNTLVLMV 763
C+V P ++ ++F+T S G+ L VT N E S+ L DN+ ++
Sbjct: 861 CNVSSPIFKAGHSVALQMMFNTLVNSSWGDSVELHANVTC---NNEDSDLLEDNSATTII 917
Query: 764 PLMHEVDTSITGIMSPTSFV 783
P+++ ++ I T +V
Sbjct: 918 PILYPINILIQDQEDSTLYV 937
Score = 36.6 bits (83), Expect = 0.13
Identities = 15/37 (40%), Positives = 28/37 (75%)
Query: 981 WIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEA 1017
++ +S + G+L+ LL+ ++L+K+GFF+R KE +EA
Sbjct: 1091 YLYVLSGIGGLLLLLLIFIVLYKVGFFKRNLKEKMEA 1127
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 213 bits (541), Expect = 1e-54
Identities = 228/860 (26%), Positives = 386/860 (44%), Gaps = 99/860 (11%)
Query: 190 EHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGY 249
EH Q G + T ++ GS+ WAG + + + + V + YLGY
Sbjct: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406
Query: 250 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLC 309
A A +V GAP+ + IG V +FR + +G G ++G+YFG+SLC
Sbjct: 407 A--AAIILRNRVQSLVLGAPRYQHIGLVAMFR--QNTGMWESNANVKGTQIGAYFGASLC 462
Query: 310 AVDLNGDGLSDL-LVGAPMFSEIRDEGQVTVY-INRGNGALEEQLALTGD-GAYNAHFGE 366
+VD++ +G +DL L+GAP + E GQV+V + RG + L G+ G FG
Sbjct: 463 SVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGRARWQCDAVLYGEQGQPWGRFGA 522
Query: 367 SIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAG-GIVPQYSMKLSGQKINPVLRM 425
++ L D++ D DVAIGAP E+D GAVY++HG +G GI P +S +++G K++P L+
Sbjct: 523 ALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQY 582
Query: 426 FGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVD-VSIFLPGSINITAPQCHD 484
FGQS+SGG D+ +G D+TVGA V+LLR++PV+ V + F P + +C+D
Sbjct: 583 FGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECND 640
Query: 485 --------GQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLG 536
G+ V CL+V S + G+I V+ D+A R F
Sbjct: 641 QVVKGKEAGEVRV-CLHVQK--STRDRLREGQI--QSVVTYDLALDSGRPHSRAVF---N 692
Query: 537 ETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPL 596
ET + Q+ + +TC + ++D +SPIV +SL G L
Sbjct: 693 ETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL----VGTPLSAFGNL 748
Query: 597 TPVLRWKKGQKIAQKNQTV---FERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGAV 652
PVL + AQ+ T FE+NC +++ C DL + + S+D L +G
Sbjct: 749 RPVL-----AEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFM--SLD----CLVVGGP 797
Query: 653 KNISLNISISNLGDDAYDANVSFNVSRELFF------INMWQKEEMGISCELLESDFL-- 704
+ ++ +++ N G+D+Y V+F +L + N + ++CE S +
Sbjct: 798 REFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVSG 857
Query: 705 -----KCSVGFPFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDN 757
CS+ P S+ F++ FD + G + +L VT+++ N R+ +
Sbjct: 858 ALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRT---NKT 913
Query: 758 TLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGP 817
L +P+ + V +T +G S NF ++ + + QV N G
Sbjct: 914 EFQLELPVKYAVYMVVTS--------HGVSTKYLNFTASENTS---RVMQHQYQVSNLGQ 962
Query: 818 STLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTI 877
+LP S V + P RL+ V ++ +F +N + +E+
Sbjct: 963 RSLPISLVFL-VPVRLN-----------QTVIWDRPQVTFSENLSSTCHTKERLPSHSDF 1010
Query: 878 FAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQF 937
A K+ V++C C C+ +E + L+ + K S + +
Sbjct: 1011 LAELRKA--PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLLI 1066
Query: 938 MSRAKVKVDPALRVVEIAHGN--PEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFL 995
+S A++ + ++ + G + E P +VG S + G+L+
Sbjct: 1067 VSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVG-----SSVGGLLLLA 1121
Query: 996 LLAVLLWKMGFFRRRYKEII 1015
L+ L+K+GFF+R+YK+++
Sbjct: 1122 LITAALYKLGFFKRQYKDMM 1141
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 209 bits (533), Expect = 8e-54
Identities = 229/861 (26%), Positives = 387/861 (44%), Gaps = 100/861 (11%)
Query: 190 EHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGY 249
EH Q G + T ++ GS+ WAG + + + + V + YLGY
Sbjct: 347 EHEMSQEGFSAAITSNGPLLSTVGSYDWAGGVFLYTSKEKSTFINMTRVDSDMNDAYLGY 406
Query: 250 AVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLC 309
A A +V GAP+ + IG V +FR + +G G ++G+YFG+SLC
Sbjct: 407 A--AAIILRNRVQSLVLGAPRYQHIGLVAMFR--QNTGMWESNANVKGTQIGAYFGASLC 462
Query: 310 AVDLNGDGLSDL-LVGAPMFSEIRDEGQVTVY-INRGNGALEE-QLALTGD-GAYNAHFG 365
+VD++ +G +DL L+GAP + E GQV+V + RG A + L G+ G FG
Sbjct: 463 SVDVDSNGSTDLVLIGAPHYYEQTRGGQVSVCPLPRGQRARWQCDAVLYGEQGQPWGRFG 522
Query: 366 ESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDAG-GIVPQYSMKLSGQKINPVLR 424
++ L D++ D DVAIGAP E+D GAVY++HG +G GI P +S +++G K++P L+
Sbjct: 523 AALTVLGDVNGDKLTDVAIGAPGEEDNRGAVYLFHGTSGSGISPSHSQRIAGSKLSPRLQ 582
Query: 425 MFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVD-VSIFLPGSINITAPQCH 483
FGQS+SGG D+ +G D+TVGA V+LLR++PV+ V + F P + +C+
Sbjct: 583 YFGQSLSGGQDLTMDGLVDLTVGA--QGHVLLLRSQPVLRVKAIMEFNPREVARNVFECN 640
Query: 484 D--------GQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLL 535
D G+ V CL+V S + G+I V+ D+A R F
Sbjct: 641 DQVVKGKEAGEVRV-CLHVQK--STRDRLREGQI--QSVVTYDLALDSGRPHSRAVF--- 692
Query: 536 GETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPP 595
ET + Q+ + +TC + ++D +SPIV +SL G
Sbjct: 693 NETKNSTRRQTQVLGLTQTCETLKLQLPNCIEDPVSPIVLRLNFSL----VGTPLSAFGN 748
Query: 596 LTPVLRWKKGQKIAQKNQTV---FERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGA 651
L PVL + AQ+ T FE+NC +++ C DL + + S+D L +G
Sbjct: 749 LRPVL-----AEDAQRLFTALFPFEKNCGNDNICQDDLSITFSFM--SLD----CLVVGG 797
Query: 652 VKNISLNISISNLGDDAYDANVSFNVSRELFF------INMWQKEEMGISCELLESDFL- 704
+ ++ +++ N G+D+Y V+F +L + N + ++CE S +
Sbjct: 798 PREFNVTVTVRNDGEDSYRTQVTFFFPLDLSYRKVSTLQNQRSQRSWRLACESASSTEVS 857
Query: 705 ------KCSVGFPFMRSKSKYEFSVIFDTSHLS--GEEEVLSFIVTAQSGNTERSESLHD 756
CS+ P S+ F++ FD + G + +L VT+++ N R+ +
Sbjct: 858 GALKSTSCSINHPIFPENSEVTFNITFDVDSKASLGNKLLLKANVTSEN-NMPRT---NK 913
Query: 757 NTLVLMVPLMHEVDTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTG 816
L +P+ + V +T +G S NF ++ + + QV N G
Sbjct: 914 TEFQLELPVKYAVYMVVTS--------HGVSTKYLNFTASENTS---RVMQHQYQVSNLG 962
Query: 817 PSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHT 876
+LP S V + P RL+ V ++ +F +N + +E+
Sbjct: 963 QRSLPISLVFL-VPVRLN-----------QTVIWDRPQVTFSENLSSTCHTKERLPSHSD 1010
Query: 877 IFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQ 936
A K+ V++C C C+ +E + L+ + K S + +
Sbjct: 1011 FLAELRKA--PVVNCSI--AVCQRIQCDIPFFGIQEEFNATLKGNLSFDWYIKTSHNHLL 1066
Query: 937 FMSRAKVKVDPALRVVEIAHGN--PEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIF 994
+S A++ + ++ + G + E P +VG S + G+L+
Sbjct: 1067 IVSTAEILFNDSVFTLLPGQGAFVRSQTETKVEPFEVPNPLPLIVG-----SSVGGLLLL 1121
Query: 995 LLLAVLLWKMGFFRRRYKEII 1015
L+ L+K+GFF+R+YK+++
Sbjct: 1122 ALITAALYKLGFFKRQYKDMM 1142
>gi|148728188 integrin, alpha E precursor [Homo sapiens]
Length = 1179
Score = 207 bits (528), Expect = 3e-53
Identities = 232/862 (26%), Positives = 379/862 (43%), Gaps = 156/862 (18%)
Query: 199 AGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNR-----RYTYLGYAVTA 253
A E V++GA G+F W+G + + LN +Y+YLGYAV
Sbjct: 408 AQILDERQVLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAV 467
Query: 254 GHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDL 313
H + ++ + GAP+ K G V+ + + R + + + + G++MGSYFGS LC VD+
Sbjct: 468 LHKT--CSLSYIAGAPRYKHHGAVFELQKEGREASFLPVLE--GEQMGSYFGSELCPVDI 523
Query: 314 NGDGLSD-LLVGAPMFSEIRDEGQVTVY-INRGNGALEEQLALTGD-GAYNAHFGESIAS 370
+ DG +D LLV AP + +EG+V VY ++ +G+ L+G G NA FG ++A+
Sbjct: 524 DMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAA 583
Query: 371 LDDLDNDGFPDVAIGAPKE----DDFA--GAVYIYHGDAGGIVPQYSMKLSGQKINPVLR 424
+ DL D DVAIGAP E DD A G+VYIY+G G+ S ++ + P L+
Sbjct: 584 MGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQ 643
Query: 425 MFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQCH 483
FG S++GG D+ G+G D+TVG V+ R+RPV+ + VS+ F P ++ I
Sbjct: 644 YFGMSMAGGFDISGDGLADITVGTL--GQAVVFRSRPVVRLKVSMAFTPSALPI------ 695
Query: 484 DGQQPVNCLNVTTCFSFHGKHVPGEIG-----LNYVLMADVAKKEKGQMPRVYFVLLG-- 536
G V +NV CF E G LN+ L DV K+ + LG
Sbjct: 696 -GFNGV--VNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCL 752
Query: 537 ---ETMGQVTEKLQLTYME-ETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERE 592
+ Q+ E L L E E C +D S + +Y L T E + +
Sbjct: 753 REWSSGSQLCEDLLLMPTEGELCE----------EDCFSNASVKVSYQLQ---TPEGQTD 799
Query: 593 LPPLTPVL-RWKKGQKIAQKNQTVFERNCRSE-DCAADLQLQGKLLLSSMDEKTLYLALG 650
P P+L R+ + I Q +E+ C+++ C A+LQL + S E L +G
Sbjct: 800 HP--QPILDRYTEPFAIF---QLPYEKACKNKLFCVAELQLATTV---SQQE----LVVG 847
Query: 651 AVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCE----LLESDFLKC 706
K ++LNI+++N G+D+Y +++ N R L M + I C+ + + C
Sbjct: 848 LTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVASVLIMNC 907
Query: 707 SVGFPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTL------- 759
+G P ++ +S SV++ + VT + N RS + +TL
Sbjct: 908 RIGHPVLK-RSSAHVSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQFRHGFV 966
Query: 760 -VLMVPLMHEVDTSITGIMSPTSF---VYGESVDAANFIQLDDLECHFQPINITLQVYNT 815
VL P + V+T G+ F V+GE++ A + L+ LQV
Sbjct: 967 AVLSKPSIMYVNTG-QGLSHHKEFLFHVHGENLFGAEY----QLQICVPTKLRGLQVVAV 1021
Query: 816 GPSTLPGSSVSISFPNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFH 875
T +S ++ + + + HV+E + C+I ++EN+
Sbjct: 1022 KKLTRTQASTVCTWSQERACAYSSVQHVEEW-------------HSVSCVIASDKENV-- 1066
Query: 876 TIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVI 935
+A E S ++E L KD V
Sbjct: 1067 -------------------------------TVAAEISWD-------HSEELLKD---VT 1085
Query: 936 QFMSRAKVKVDPALRVVEIAHGNPEEVTVVF---EALHNLEPRGYVVGWIIAISLLVGIL 992
+ ++ + +L A + ++TVVF E H+L II + G+L
Sbjct: 1086 ELQILGEISFNKSLYEGLNAENHRTKITVVFLKDEKYHSLP--------IIIKGSVGGLL 1137
Query: 993 IFLLLAVLLWKMGFFRRRYKEI 1014
+ +++ V+L+K GFF+R+Y+++
Sbjct: 1138 VLIVILVILFKCGFFKRKYQQL 1159
>gi|62548866 integrin, alpha D precursor [Homo sapiens]
Length = 1161
Score = 201 bits (511), Expect = 3e-51
Identities = 223/852 (26%), Positives = 383/852 (44%), Gaps = 86/852 (10%)
Query: 190 EHGSCQAGIAGFFTEELVVMGAPGSFYWAGTIKVL--NLTDNTYLKLNDEVIMNRRYTYL 247
+H Q G + T + + +GA GSF W+G + N++ T++ ++ E + + R +YL
Sbjct: 347 QHEMSQEGFSTALTMDGLFLGAVGSFSWSGGAFLYPPNMSP-TFINMSQENV-DMRDSYL 404
Query: 248 GYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSS 307
GY+ + ++V GAP+ + GK IF R K + +G ++GSYFG+S
Sbjct: 405 GYSTELALWK--GVQNLVLGAPRYQHTGKAVIFTQVSRQWR--KKAEVTGTQIGSYFGAS 460
Query: 308 LCAVDLNGDGLSDL-LVGAPMFSEIRDEGQVTVY-INRGNGALEEQLALTGDGAYN-AHF 364
LC+VD++ DG +DL L+GAP + E GQV+V + RG + L G+ + F
Sbjct: 461 LCSVDVDSDGSTDLILIGAPHYYEQTRGGQVSVCPLPRGRVQWQCDAVLRGEQGHPWGRF 520
Query: 365 GESIASLDDLDNDGFPDVAIGAPKEDDFAGAVYIYHGDA-GGIVPQYSMKLSGQKINPVL 423
G ++ L D++ D DVAIGAP E + GAVY++HG + GI P +S +++ +++P L
Sbjct: 521 GAALTVLGDVNEDKLIDVAIGAPGEQENRGAVYLFHGASESGISPSHSQRIASSQLSPRL 580
Query: 424 RMFGQSISGGIDMDGNGYPDVTVGAFMSDSVVLLRARPVITVDVSI-FLPGSINITAPQC 482
+ FGQ++SGG D+ +G D+ VGA V+LLR+ PV+ V V++ F P + +C
Sbjct: 581 QYFGQALSGGQDLTQDGLMDLAVGA--RGQVLLLRSLPVLKVGVAMRFSPVEVAKAVYRC 638
Query: 483 -HDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADVAKKEKGQMPRVYFVLLGETMGQ 541
+ + + T C + + + + D+A R F ET
Sbjct: 639 WEEKPSALEAGDATVCLTIQKSSLDQLGDIQSSVRFDLALDPGRLTSRAIF---NETKNP 695
Query: 542 VTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEHVTGEEERELPPLTPVLR 601
+ + + C + V+DV+SPI+ +SL + L PVL
Sbjct: 696 TLTRRKTLGLGIHCETLKLLLPDCVEDVVSPIILHLNFSLVREPIPSPQN----LRPVL- 750
Query: 602 WKKGQKIAQKNQTVFERNCRSED-CAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNIS 660
G + FE+NC + C DL + L S + L +G+ +++ ++
Sbjct: 751 -AVGSQDLFTASLPFEKNCGQDGLCEGDLGV--TLSFSGLQT----LTVGSSLELNVIVT 803
Query: 661 ISNLGDDAYDANVSFNVSRELFF--INMWQKE----EMGISCELLESD-----FLKCSVG 709
+ N G+D+Y VS L ++ QK+ + ++CE + ++ +CSV
Sbjct: 804 VWNAGEDSYGTVVSLYYPAGLSHRRVSGAQKQPHQSALRLACETVPTEDEGLRSSRCSVN 863
Query: 710 FPFMRSKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEV 769
P S F V FD S+ + + + +A S N + S S T L +P+ + V
Sbjct: 864 HPIFHEGSNGTFIVTFDVSYKATLGDRMLMRASASSENNKASSS--KATFQLELPVKYAV 921
Query: 770 DTSITGIMSPTSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISF 829
T I+ ES NF D E + +V N L ++SI+F
Sbjct: 922 YTMISR--------QEESTKYFNFATSD--EKKMKEAEHRYRVNNLSQRDL---AISINF 968
Query: 830 PNRLSSGGAEMFHVQEMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRK-V 888
+ G ++ V M + C ++ P PQ + F T+ R +
Sbjct: 969 WVPVLLNGVAVWDV-VMEAPSQSLPCVSERKP-----PQHSD--------FLTQISRSPM 1014
Query: 889 LDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPA 948
LDC CL C+ + + +E + L+ +++ + +S A++ D +
Sbjct: 1015 LDCSI--ADCLQFRCDVPSFSVQEELDFTLKGNLSFGWVRETLQKKVLVVSVAEITFDTS 1072
Query: 949 ----LRVVEIAHGNPEEVTVVFEALHNLEPRGYVVGWIIAISLLVGILIFLLLAVLLWKM 1004
L E E+ + + ++N P II S + +L+ L+ L+K+
Sbjct: 1073 VYSQLPGQEAFMRAQMEMVLEEDEVYNAIP-------IIMGSSVGALLLLALITATLYKL 1125
Query: 1005 GFFRRRYKEIIE 1016
GFF+R YKE++E
Sbjct: 1126 GFFKRHYKEMLE 1137
>gi|29171717 glycosylphosphatidylinositol specific phospholipase D1
isoform 1 precursor [Homo sapiens]
Length = 840
Score = 58.5 bits (140), Expect = 3e-08
Identities = 50/158 (31%), Positives = 82/158 (51%), Gaps = 19/158 (12%)
Query: 305 GSSLCAVDLNGDGLSDLLVGAPMFSEIRDEGQVTVYINRGNGA--------LEEQLALTG 356
G ++ + DLN DG DL+VGAP +S VY+ GN L+++
Sbjct: 382 GWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEAHRIL 441
Query: 357 DGAY-NAHFGESIASLDDLDNDGFPDVAIGAP----KEDDFAGAVYIYHGD-AGGIVPQY 410
+G + FG ++A LD + DG PD+A+GAP ++ + GAVY+Y G GG+
Sbjct: 442 EGFQPSGRFGSALAVLD-FNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSKQGGMSSSP 500
Query: 411 SMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGA 448
++ +S Q I L G ++ D++G+ PD+ +G+
Sbjct: 501 NITISCQDIYCNL---GWTLLAA-DVNGDSEPDLVIGS 534
Score = 57.8 bits (138), Expect = 5e-08
Identities = 46/165 (27%), Positives = 77/165 (46%), Gaps = 28/165 (16%)
Query: 244 YTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRA-----------------DRRS 286
Y LG+A+T+ + D+V GAP G ++I R D+ +
Sbjct: 378 YARLGWAMTSADLNQDGHGDLVVGAPGYSRPGHIHIGRVYLIYGNDLGLPPVDLDLDKEA 437
Query: 287 GTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMF--SEIRDEGQVTVYINRG 344
+++ FQ SG+ FGS+L +D N DG+ DL VGAP ++ +G V VY
Sbjct: 438 HRILEGFQPSGR-----FGSALAVLDFNVDGVPDLAVGAPSVGSEQLTYKGAVYVYFGSK 492
Query: 345 NGALEE--QLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAP 387
G + + ++ Y + G ++ + D++ D PD+ IG+P
Sbjct: 493 QGGMSSSPNITISCQDIY-CNLGWTLLAA-DVNGDSEPDLVIGSP 535
Score = 43.1 bits (100), Expect = 0.001
Identities = 46/158 (29%), Positives = 69/158 (43%), Gaps = 37/158 (23%)
Query: 270 QDKGIGKVY-IFRADRRSGTLIKIFQASGKKMGSYFGSSLCA--VDLNGDGLSDLLVGAP 326
+ K +G+VY F + +S F SG K G+SL + V +NG LLVGAP
Sbjct: 617 EKKSLGRVYGYFPPNGQSW-----FTISGDKAMGKLGTSLSSGHVLMNGTLKQVLLVGAP 671
Query: 327 MFSEIRDEGQVTVYINRGNGALEEQLALTGDG-----------AYNAHFGESIASLDDLD 375
+ ++ +TV +++G ALT D + FG + L DLD
Sbjct: 672 TYDDVSKVAFLTVTLHQGGAT--RMYALTSDAQPLLLSTFSGDRRFSRFG-GVLHLSDLD 728
Query: 376 NDGFPDVAIGAP------------KEDDFAGAVYIYHG 401
+DG ++ + AP ED G VY+Y+G
Sbjct: 729 DDGLDEIIMAAPLRIADVTSGLIGGED---GRVYVYNG 763
Score = 35.0 bits (79), Expect = 0.37
Identities = 64/238 (26%), Positives = 98/238 (41%), Gaps = 41/238 (17%)
Query: 244 YTYLGYAVTAGHFSHPSTIDVVGGAPQDKGIGKVYIFRADRRSGTLIK----------IF 293
Y LG+ + A + S D+V G+P G GK A SG + +
Sbjct: 510 YCNLGWTLLAADVNGDSEPDLVIGSPFAPGGGKQKGIVAAFYSGPSLSDKEKLNVEAANW 569
Query: 294 QASGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPMFS---------EIRDE----GQVTVY 340
G++ S+FG SL V + D + LLVG+P + IRDE G+V Y
Sbjct: 570 TVRGEEDFSWFGYSLHGVTV--DNRTLLLVGSPTWKNASRLGHLLHIRDEKKSLGRVYGY 627
Query: 341 INRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDV-AIGAPKEDDFAGAVYI- 398
NG + ++GD A G S++S L N V +GAP DD + ++
Sbjct: 628 F-PPNG--QSWFTISGDKAM-GKLGTSLSSGHVLMNGTLKQVLLVGAPTYDDVSKVAFLT 683
Query: 399 YHGDAGGIVPQYSMKLSGQKINPVLRMFGQ----SISGGI----DMDGNGYPDVTVGA 448
GG Y++ Q + +L F S GG+ D+D +G ++ + A
Sbjct: 684 VTLHQGGATRMYALTSDAQPL--LLSTFSGDRRFSRFGGVLHLSDLDDDGLDEIIMAA 739
Score = 33.1 bits (74), Expect = 1.4
Identities = 25/95 (26%), Positives = 41/95 (43%), Gaps = 14/95 (14%)
Query: 247 LGYAVTAGHFSHPSTIDVV--GGAPQDKGIGKVYIFRADRRSGTLIKIFQA--------- 295
LG ++++GH T+ V GAP + KV G +++
Sbjct: 647 LGTSLSSGHVLMNGTLKQVLLVGAPTYDDVSKVAFLTVTLHQGGATRMYALTSDAQPLLL 706
Query: 296 ---SGKKMGSYFGSSLCAVDLNGDGLSDLLVGAPM 327
SG + S FG L DL+ DGL ++++ AP+
Sbjct: 707 STFSGDRRFSRFGGVLHLSDLDDDGLDEIIMAAPL 741
>gi|239751058 PREDICTED: hypothetical protein XP_002347690 [Homo
sapiens]
Length = 462
Score = 56.2 bits (134), Expect = 2e-07
Identities = 94/447 (21%), Positives = 176/447 (39%), Gaps = 67/447 (14%)
Query: 616 FERNCRSEDCAADLQLQGKLLLSSMDEKTLYLALGAVKNISLNISISNLGDDAYDANVSF 675
FE+NC AD Q L +S L +G+ ++ + + N G+D+Y ++F
Sbjct: 16 FEKNC-----GADHICQDNLGISFSFPGLKSLLVGSNLELNAEVMVWNDGEDSYGTTITF 70
Query: 676 NVSRELFFINMWQKEEMG------ISCELLESDF-----LKCSVGFPFMRSKSKYEFSVI 724
+ L + + + ++ G ++C+ C + R ++ F
Sbjct: 71 SHPAGLSYRYVAEGQKQGQLRSLHLTCDSAPVGSQGTWSTSCRINHLIFRGGAQITFLAT 130
Query: 725 FDTSHLS--GEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSPTSF 782
FD S + G+ +L+ V++++ NT R+ T L +P+ + V T ++ T +
Sbjct: 131 FDVSPKAVLGDRLLLTANVSSEN-NTPRTSK---TTFQLELPVKYAVYTVVSSHEQFTKY 186
Query: 783 V-YGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMF 841
+ + ES + + + + + V N G LP VSI+F + ++
Sbjct: 187 LNFSESEEKESHVAMHRYQAGGGDAGDWAGVNNLGQRDLP---VSINFWVPVELNQEAVW 243
Query: 842 HVQEMVVGQEKGNCSFQKNPTP---------------------CIIPQE------QENIF 874
E+ Q +C + + P CI PQ E I
Sbjct: 244 MDVEVSHPQVPKDCMWLLHECPFYLDSLCPMWVPDVPAETLVLCIFPQNPSLRCSSEKIA 303
Query: 875 HTIFAFFTKSGRK-VLDCEKPGISCLTAHCNFSALAKEESRTIDIYMLLNTEILKKDSSS 933
F + VLDC G CL C+ + + +E + L+ +++
Sbjct: 304 PPASDFLAHIQKNPVLDCSIAG--CLRFRCDVPSFSVQEELDFTLKGNLSFGWVRQILQK 361
Query: 934 VIQFMSRAKVKVDPALRVVEIAHGNPE----EVTVVFEALHNLEPRGYVVGWIIAISLLV 989
+ +S A++ D + V G + T V E P +VG S +
Sbjct: 362 KVSVVSVAEITFDTS--VYSQLPGQEAFMRAQTTTVLEKYKVHNPTPLIVG-----SSIG 414
Query: 990 GILIFLLLAVLLWKMGFFRRRYKEIIE 1016
G+L+ L+ +L+K+GFF+R+YKE++E
Sbjct: 415 GLLLLALITAVLYKVGFFKRQYKEMME 441
>gi|171184408 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 35.8 bits (81), Expect = 0.21
Identities = 16/47 (34%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 974 PRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKN 1020
P GY +GW +A+S +V + +F+++ LL G FR+R +++I + +
Sbjct: 533 PWGYSIGWFLALSSMVCVPLFVVI-TLLKTRGPFRKRLRQLITPDSS 578
>gi|171184406 solute carrier family 6 (neurotransmitter transporter,
betaine/GABA), member 12 [Homo sapiens]
Length = 614
Score = 35.8 bits (81), Expect = 0.21
Identities = 16/47 (34%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 974 PRGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKN 1020
P GY +GW +A+S +V + +F+++ LL G FR+R +++I + +
Sbjct: 533 PWGYSIGWFLALSSMVCVPLFVVI-TLLKTRGPFRKRLRQLITPDSS 578
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.137 0.412
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,941,283
Number of Sequences: 37866
Number of extensions: 1927251
Number of successful extensions: 4351
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 3955
Number of HSP's gapped (non-prelim): 63
length of query: 1035
length of database: 18,247,518
effective HSP length: 112
effective length of query: 923
effective length of database: 14,006,526
effective search space: 12928023498
effective search space used: 12928023498
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.