Guide to the Human Genome
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Search of human proteins with 5174717

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5174717 T-cell, immune regulator 1 isoform b [Homo sapiens]
         (614 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5174717 T-cell, immune regulator 1 isoform b [Homo sapiens]       1232   0.0  
gi|19924145 T-cell, immune regulator 1 isoform a [Homo sapiens]      1232   0.0  
gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Ho...   652   0.0  
gi|85386547 ATPase, H+ transporting, lysosomal V0 subunit a4 [Ho...   607   e-173
gi|85386056 ATPase, H+ transporting, lysosomal V0 subunit a4 [Ho...   607   e-173
gi|85386053 ATPase, H+ transporting, lysosomal V0 subunit a4 [Ho...   607   e-173
gi|194097403 ATPase, H+ transporting, lysosomal V0 subunit a1 is...   589   e-168
gi|19913418 ATPase, H+ transporting, lysosomal V0 subunit a1 iso...   588   e-168
gi|194097401 ATPase, H+ transporting, lysosomal V0 subunit a1 is...   588   e-168
gi|7661960 Rough Deal homolog, centromere/kinetochore protein [H...    31   3.8  
gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]        31   3.8  
gi|46559747 hypothetical protein LOC399947 [Homo sapiens]              31   3.8  
gi|130980075 centromere protein J [Homo sapiens]                       30   5.0  
gi|117414154 sodium channel associated protein 2 isoform b [Homo...    30   5.0  
gi|117414162 sodium channel associated protein 2 isoform a [Homo...    30   5.0  
gi|71274154 Scm-like with four mbt domains 2 [Homo sapiens]            30   5.0  
gi|13899255 membrane frizzled-related protein [Homo sapiens]           30   6.5  
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa...    30   6.5  
gi|7657345 mitochondrial carrier homolog 1 [Homo sapiens]              30   6.5  
gi|7657326 male-enhanced antigen [Homo sapiens]                        30   6.5  
gi|149944680 HAUS augmin-like complex, subunit 5 [Homo sapiens]        30   8.5  
gi|5453726 leucine rich repeat (in FLII) interacting protein 2 i...    30   8.5  
gi|7705268 family with sequence similarity 8, member A1 [Homo sa...    30   8.5  
gi|157042792 coiled-coil domain containing 64B [Homo sapiens]          30   8.5  

>gi|5174717 T-cell, immune regulator 1 isoform b [Homo sapiens]
          Length = 614

 Score = 1232 bits (3187), Expect = 0.0
 Identities = 614/614 (100%), Positives = 614/614 (100%)

Query: 1   MTFLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETER 60
           MTFLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETER
Sbjct: 1   MTFLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETER 60

Query: 61  FLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEAL 120
           FLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEAL
Sbjct: 61  FLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEAL 120

Query: 121 RDSSMEEGVSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
           RDSSMEEGVSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF
Sbjct: 121 RDSSMEEGVSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY
Sbjct: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI 300
           TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI
Sbjct: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI 300

Query: 301 DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF 360
           DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF
Sbjct: 301 DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF 360

Query: 361 LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATL 420
           LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATL
Sbjct: 361 LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATL 420

Query: 421 VVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKA 480
           VVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKA
Sbjct: 421 VVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKA 480

Query: 481 GGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVM 540
           GGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVM
Sbjct: 481 GGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVM 540

Query: 541 RIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGT 600
           RIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGT
Sbjct: 541 RIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGT 600

Query: 601 GYKLSPFTFAATDD 614
           GYKLSPFTFAATDD
Sbjct: 601 GYKLSPFTFAATDD 614


>gi|19924145 T-cell, immune regulator 1 isoform a [Homo sapiens]
          Length = 830

 Score = 1232 bits (3187), Expect = 0.0
 Identities = 614/614 (100%), Positives = 614/614 (100%)

Query: 1   MTFLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETER 60
           MTFLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETER
Sbjct: 217 MTFLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETER 276

Query: 61  FLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEAL 120
           FLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEAL
Sbjct: 277 FLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEAL 336

Query: 121 RDSSMEEGVSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
           RDSSMEEGVSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF
Sbjct: 337 RDSSMEEGVSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 396

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY
Sbjct: 397 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 456

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI 300
           TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI
Sbjct: 457 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI 516

Query: 301 DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF 360
           DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF
Sbjct: 517 DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF 576

Query: 361 LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATL 420
           LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATL
Sbjct: 577 LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQATL 636

Query: 421 VVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKA 480
           VVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKA
Sbjct: 637 VVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKA 696

Query: 481 GGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVM 540
           GGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVM
Sbjct: 697 GGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLWAMVM 756

Query: 541 RIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGT 600
           RIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGT
Sbjct: 757 RIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKFYSGT 816

Query: 601 GYKLSPFTFAATDD 614
           GYKLSPFTFAATDD
Sbjct: 817 GYKLSPFTFAATDD 830


>gi|42741679 ATPase, H+ transporting, lysosomal V0 subunit A2 [Homo
           sapiens]
          Length = 856

 Score =  652 bits (1681), Expect = 0.0
 Identities = 335/627 (53%), Positives = 431/627 (68%), Gaps = 27/627 (4%)

Query: 3   FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFL 62
           FLIS+WGEQIG K++KI DC+HCHV+P+    E R    + L  + Q+L  VL +TE +L
Sbjct: 225 FLISFWGEQIGHKVKKICDCYHCHVYPYPNTAEERREIQEGLNTRIQDLYTVLHKTEDYL 284

Query: 63  SQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRD 122
            QVL +  + +    +QV KMKA+Y  LN CS   T+KCLIAE WC   DL  L+ AL +
Sbjct: 285 RQVLCKAAESVYSRVIQVKKMKAIYHMLNMCSFDVTNKCLIAEVWCPEADLQDLRRALEE 344

Query: 123 SSMEEG--VSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
            S E G  + +  + IP ++ PPT IRTN+FT  FQ IVDAYGVG Y+EVNPA +TIITF
Sbjct: 345 GSRESGATIPSFMNIIPTKETPPTRIRTNKFTEGFQNIVDAYGVGSYREVNPALFTIITF 404

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGD GHG +MFLFAL +VL EN P +  +Q EI + FF GRY+LLLMGLFS+Y
Sbjct: 405 PFLFAVMFGDFGHGFVMFLFALLLVLNENHPRLNQSQ-EIMRMFFNGRYILLLMGLFSVY 463

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSG----------WSDAFLAQHTMLTLDPNVTG 290
           TG IYN+CFS++ ++F SGW+V+AM + S           W+D+ +  +++L LDP++ G
Sbjct: 464 TGLIYNDCFSKSVNLFGSGWNVSAMYSSSHPPAEHKKMVLWNDSVVRHNSILQLDPSIPG 523

Query: 291 VFLGPYPFGIDPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRL 350
           VF GPYP GIDPIW+LA N L+FLNSFKMKMSVILG++HM FGV+LG+FNH+HF ++  +
Sbjct: 524 VFRGPYPLGIDPIWNLATNRLTFLNSFKMKMSVILGIIHMTFGVILGIFNHLHFRKKFNI 583

Query: 351 LLETLPELTFLLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLY 410
            L ++PEL F+L +FGYL+F++ YKWL   A  +  APSILI FINMFLF  S ++  LY
Sbjct: 584 YLVSIPELLFMLCIFGYLIFMIFYKWLVFSAETSRVAPSILIEFINMFLFPASKTSG-LY 642

Query: 411 PRQEVVQATLVVLALAMVPILLLGTPLHLLHRHR-------RRLRRRPADRQEENKAGLL 463
             QE VQ  L+V+    VP+L LG PL LL  H         R       +  E +  LL
Sbjct: 643 TGQEYVQRVLLVVTALSVPVLFLGKPLFLLWLHNGRSCFGVNRSGYTLIRKDSEEEVSLL 702

Query: 464 DLPDASVNGWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWA 523
              D        + +   G  +    E    E+LM Q IH+IE+CLGC+SNTASYLRLWA
Sbjct: 703 GSQDIE----EGNHQVEDGCREMACEEFNFGEILMTQVIHSIEYCLGCISNTASYLRLWA 758

Query: 524 LSLAHAQLSEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLH 583
           LSLAHAQLS+VLWAM+MR+GL +    GV  ++L+P+ A FAV+T+ ILL+MEGLSAFLH
Sbjct: 759 LSLAHAQLSDVLWAMLMRVGLRVDTTYGV--LLLLPVIALFAVLTIFILLIMEGLSAFLH 816

Query: 584 ALRLHWVEFQNKFYSGTGYKLSPFTFA 610
           A+RLHWVEFQNKFY G G K  PF+F+
Sbjct: 817 AIRLHWVEFQNKFYVGAGTKFVPFSFS 843


>gi|85386547 ATPase, H+ transporting, lysosomal V0 subunit a4 [Homo
           sapiens]
          Length = 840

 Score =  607 bits (1564), Expect = e-173
 Identities = 325/613 (53%), Positives = 408/613 (66%), Gaps = 10/613 (1%)

Query: 3   FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFL 62
           F+I Y GEQ+ QKI+KI D F   V+P  +    R   L+ +  + ++L  V+ +TE   
Sbjct: 222 FIIFYQGEQLRQKIKKICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHR 281

Query: 63  SQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRD 122
            ++L           ++V KMKAVY  LN C++  T +C+IAE W  V D   ++ AL  
Sbjct: 282 QRLLQEAAANWHSWLIKVQKMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQ 341

Query: 123 SSMEEGVSA--VAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
                G S   +   +  +  PPT  RTN+FTA FQ IVDAYGVG Y+E+NPAPYTIITF
Sbjct: 342 GMELSGSSMAPIMTTVQSKTAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITF 401

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGD GHG +M L AL M+L E R   +   NEIW TFF GRYL+LLMG+FSIY
Sbjct: 402 PFLFAVMFGDCGHGTVMLLAALWMILNERRLLSQKTDNEIWNTFFHGRYLILLMGIFSIY 461

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLG-PYPFG 299
           TG IYN+CFS++ +IF S WSV  M     W+   + +   L LDP + GV+ G PYPFG
Sbjct: 462 TGLIYNDCFSKSLNIFGSSWSVQPMFRNGTWNTHVMEESLYLQLDPAIPGVYFGNPYPFG 521

Query: 300 IDPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELT 359
           IDPIW+LA+N L+FLNS+KMKMSVILG+V M FGV+L +FNH++F +   ++L+ +PE+ 
Sbjct: 522 IDPIWNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMI 581

Query: 360 FLLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHS-PSNRLLYPRQEVVQA 418
           F+L LFGYLVF++I+KW C     +  APSILIHFINMFLF++S  SN  LY  Q+ VQ+
Sbjct: 582 FILCLFGYLVFMIIFKWCCFDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQS 641

Query: 419 TLVVLALAMVPILLLGTP--LHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSD 476
             VV+AL  VP +LL  P  L   HR  +    R  +   EN  G    P +S +G  + 
Sbjct: 642 FFVVMALISVPWMLLIKPFILRASHRKSQLQASRIQEDATENIEGDSSSP-SSRSGQRTS 700

Query: 477 EEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLW 536
            +  G LDD  E E    +V +HQAIHTIE+CLGC+SNTASYLRLWALSLAHAQLSEVLW
Sbjct: 701 ADTHGALDDHGE-EFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW 759

Query: 537 AMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKF 596
            MVM  GL      G+  V +  IFA FAV+TVAILL+MEGLSAFLHALRLHWVEFQNKF
Sbjct: 760 TMVMNSGLQTRGWGGIVGVFI--IFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKF 817

Query: 597 YSGTGYKLSPFTF 609
           Y G GYK SPF+F
Sbjct: 818 YVGDGYKFSPFSF 830


>gi|85386056 ATPase, H+ transporting, lysosomal V0 subunit a4 [Homo
           sapiens]
          Length = 840

 Score =  607 bits (1564), Expect = e-173
 Identities = 325/613 (53%), Positives = 408/613 (66%), Gaps = 10/613 (1%)

Query: 3   FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFL 62
           F+I Y GEQ+ QKI+KI D F   V+P  +    R   L+ +  + ++L  V+ +TE   
Sbjct: 222 FIIFYQGEQLRQKIKKICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHR 281

Query: 63  SQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRD 122
            ++L           ++V KMKAVY  LN C++  T +C+IAE W  V D   ++ AL  
Sbjct: 282 QRLLQEAAANWHSWLIKVQKMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQ 341

Query: 123 SSMEEGVSA--VAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
                G S   +   +  +  PPT  RTN+FTA FQ IVDAYGVG Y+E+NPAPYTIITF
Sbjct: 342 GMELSGSSMAPIMTTVQSKTAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITF 401

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGD GHG +M L AL M+L E R   +   NEIW TFF GRYL+LLMG+FSIY
Sbjct: 402 PFLFAVMFGDCGHGTVMLLAALWMILNERRLLSQKTDNEIWNTFFHGRYLILLMGIFSIY 461

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLG-PYPFG 299
           TG IYN+CFS++ +IF S WSV  M     W+   + +   L LDP + GV+ G PYPFG
Sbjct: 462 TGLIYNDCFSKSLNIFGSSWSVQPMFRNGTWNTHVMEESLYLQLDPAIPGVYFGNPYPFG 521

Query: 300 IDPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELT 359
           IDPIW+LA+N L+FLNS+KMKMSVILG+V M FGV+L +FNH++F +   ++L+ +PE+ 
Sbjct: 522 IDPIWNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMI 581

Query: 360 FLLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHS-PSNRLLYPRQEVVQA 418
           F+L LFGYLVF++I+KW C     +  APSILIHFINMFLF++S  SN  LY  Q+ VQ+
Sbjct: 582 FILCLFGYLVFMIIFKWCCFDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQS 641

Query: 419 TLVVLALAMVPILLLGTP--LHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSD 476
             VV+AL  VP +LL  P  L   HR  +    R  +   EN  G    P +S +G  + 
Sbjct: 642 FFVVMALISVPWMLLIKPFILRASHRKSQLQASRIQEDATENIEGDSSSP-SSRSGQRTS 700

Query: 477 EEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLW 536
            +  G LDD  E E    +V +HQAIHTIE+CLGC+SNTASYLRLWALSLAHAQLSEVLW
Sbjct: 701 ADTHGALDDHGE-EFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW 759

Query: 537 AMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKF 596
            MVM  GL      G+  V +  IFA FAV+TVAILL+MEGLSAFLHALRLHWVEFQNKF
Sbjct: 760 TMVMNSGLQTRGWGGIVGVFI--IFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKF 817

Query: 597 YSGTGYKLSPFTF 609
           Y G GYK SPF+F
Sbjct: 818 YVGDGYKFSPFSF 830


>gi|85386053 ATPase, H+ transporting, lysosomal V0 subunit a4 [Homo
           sapiens]
          Length = 840

 Score =  607 bits (1564), Expect = e-173
 Identities = 325/613 (53%), Positives = 408/613 (66%), Gaps = 10/613 (1%)

Query: 3   FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFL 62
           F+I Y GEQ+ QKI+KI D F   V+P  +    R   L+ +  + ++L  V+ +TE   
Sbjct: 222 FIIFYQGEQLRQKIKKICDGFRATVYPCPEPAVERREMLESVNVRLEDLITVITQTESHR 281

Query: 63  SQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRD 122
            ++L           ++V KMKAVY  LN C++  T +C+IAE W  V D   ++ AL  
Sbjct: 282 QRLLQEAAANWHSWLIKVQKMKAVYHILNMCNIDVTQQCVIAEIWFPVADATRIKRALEQ 341

Query: 123 SSMEEGVSA--VAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
                G S   +   +  +  PPT  RTN+FTA FQ IVDAYGVG Y+E+NPAPYTIITF
Sbjct: 342 GMELSGSSMAPIMTTVQSKTAPPTFNRTNKFTAGFQNIVDAYGVGSYREINPAPYTIITF 401

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGD GHG +M L AL M+L E R   +   NEIW TFF GRYL+LLMG+FSIY
Sbjct: 402 PFLFAVMFGDCGHGTVMLLAALWMILNERRLLSQKTDNEIWNTFFHGRYLILLMGIFSIY 461

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLG-PYPFG 299
           TG IYN+CFS++ +IF S WSV  M     W+   + +   L LDP + GV+ G PYPFG
Sbjct: 462 TGLIYNDCFSKSLNIFGSSWSVQPMFRNGTWNTHVMEESLYLQLDPAIPGVYFGNPYPFG 521

Query: 300 IDPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELT 359
           IDPIW+LA+N L+FLNS+KMKMSVILG+V M FGV+L +FNH++F +   ++L+ +PE+ 
Sbjct: 522 IDPIWNLASNKLTFLNSYKMKMSVILGIVQMVFGVILSLFNHIYFRRTLNIILQFIPEMI 581

Query: 360 FLLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHS-PSNRLLYPRQEVVQA 418
           F+L LFGYLVF++I+KW C     +  APSILIHFINMFLF++S  SN  LY  Q+ VQ+
Sbjct: 582 FILCLFGYLVFMIIFKWCCFDVHVSQHAPSILIHFINMFLFNYSDSSNAPLYKHQQEVQS 641

Query: 419 TLVVLALAMVPILLLGTP--LHLLHRHRRRLRRRPADRQEENKAGLLDLPDASVNGWSSD 476
             VV+AL  VP +LL  P  L   HR  +    R  +   EN  G    P +S +G  + 
Sbjct: 642 FFVVMALISVPWMLLIKPFILRASHRKSQLQASRIQEDATENIEGDSSSP-SSRSGQRTS 700

Query: 477 EEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVLW 536
            +  G LDD  E E    +V +HQAIHTIE+CLGC+SNTASYLRLWALSLAHAQLSEVLW
Sbjct: 701 ADTHGALDDHGE-EFNFGDVFVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQLSEVLW 759

Query: 537 AMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVEFQNKF 596
            MVM  GL      G+  V +  IFA FAV+TVAILL+MEGLSAFLHALRLHWVEFQNKF
Sbjct: 760 TMVMNSGLQTRGWGGIVGVFI--IFAVFAVLTVAILLIMEGLSAFLHALRLHWVEFQNKF 817

Query: 597 YSGTGYKLSPFTF 609
           Y G GYK SPF+F
Sbjct: 818 YVGDGYKFSPFSF 830


>gi|194097403 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform b [Homo sapiens]
          Length = 837

 Score =  589 bits (1519), Expect = e-168
 Identities = 310/618 (50%), Positives = 411/618 (66%), Gaps = 21/618 (3%)

Query: 3   FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFL 62
           F+I + G+Q+  +++KI + F   ++P  +  + R      +  +  +LQ VL +TE   
Sbjct: 220 FIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHR 279

Query: 63  SQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRD 122
            +VL    + +    ++V KMKA+Y  LN C++  T KCLIAE WC V DL ++Q ALR 
Sbjct: 280 QRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRR 339

Query: 123 SSMEEG--VSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
            +   G  V ++ +R+     PPT  +TN+FT  FQ IVDAYG+G Y+E+NPAPYTIITF
Sbjct: 340 GTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITF 399

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGD GHG+LM LFA+ MVL E+R   +  +NE++ T F GRY++LLMG+FS+Y
Sbjct: 400 PFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMY 459

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI 300
           TG IYN+CFS++ +IF S WSV  M   + W++  L  + +L L+P + GVF GPYPFGI
Sbjct: 460 TGLIYNDCFSKSLNIFGSSWSVRPMFTYN-WTEETLRGNPVLQLNPALPGVFGGPYPFGI 518

Query: 301 DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF 360
           DPIW++A N L+FLNSFKMKMSVILG++HM FGV L +FNH++F +   +    +PE+ F
Sbjct: 519 DPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIF 578

Query: 361 LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSN-RLLYPRQEVVQAT 419
           +  LFGYLV L+ YKW    A  + +APS+LIHFINMFLFS+  S   +LY  Q+ +Q  
Sbjct: 579 MTSLFGYLVILIFYKWTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCF 638

Query: 420 LVVLALAMVPILLLGTPLHLLHRHRRRLRR--------RPADRQEENKAGLLDLPDASVN 471
           LVV+AL  VP +LL  PL L  ++ RR           R  +   E  A ++     S +
Sbjct: 639 LVVVALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTH 698

Query: 472 GWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQL 531
              +DE         E+      + ++HQAIHTIE+CLGC+SNTASYLRLWALSLAHAQL
Sbjct: 699 SEDADE-------PSEDEVFDFGDTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQL 751

Query: 532 SEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVE 591
           SEVLW MV+ IGL +    G   +VL   F AFA +TVAILL+MEGLSAFLHALRLHWVE
Sbjct: 752 SEVLWTMVIHIGLSVKSLAG--GLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVE 809

Query: 592 FQNKFYSGTGYKLSPFTF 609
           FQNKFYSGTG+K  PF+F
Sbjct: 810 FQNKFYSGTGFKFLPFSF 827


>gi|19913418 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform c [Homo sapiens]
          Length = 831

 Score =  588 bits (1517), Expect = e-168
 Identities = 310/618 (50%), Positives = 410/618 (66%), Gaps = 27/618 (4%)

Query: 3   FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFL 62
           F+I + G+Q+  +++KI + F   ++P  +  + R      +  +  +LQ VL +TE   
Sbjct: 220 FIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHR 279

Query: 63  SQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRD 122
            +VL    + +    ++V KMKA+Y  LN C++  T KCLIAE WC V DL ++Q ALR 
Sbjct: 280 QRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRR 339

Query: 123 SSMEEG--VSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
            +   G  V ++ +R+     PPT  +TN+FT  FQ IVDAYG+G Y+E+NPAPYTIITF
Sbjct: 340 GTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITF 399

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGD GHG+LM LFA+ MVL E+R   +  +NE++ T F GRY++LLMG+FS+Y
Sbjct: 400 PFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMY 459

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI 300
           TG IYN+CFS++ +IF S WSV  M   + W++  L  + +L L+P + GVF GPYPFGI
Sbjct: 460 TGLIYNDCFSKSLNIFGSSWSVRPMFTYN-WTEETLRGNPVLQLNPALPGVFGGPYPFGI 518

Query: 301 DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF 360
           DPIW++A N L+FLNSFKMKMSVILG++HM FGV L +FNH++F +   +    +PE+ F
Sbjct: 519 DPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIF 578

Query: 361 LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSN-RLLYPRQEVVQAT 419
           +  LFGYLV L+ YKW    A  + +APS+LIHFINMFLFS+  S   +LY  Q+ +Q  
Sbjct: 579 MTSLFGYLVILIFYKWTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCF 638

Query: 420 LVVLALAMVPILLLGTPLHLLHRHRRRLRR--------RPADRQEENKAGLLDLPDASVN 471
           LVV+AL  VP +LL  PL L  ++ RR           R  +   E  A ++     S +
Sbjct: 639 LVVVALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTH 698

Query: 472 GWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQL 531
              +DE   G             + ++HQAIHTIE+CLGC+SNTASYLRLWALSLAHAQL
Sbjct: 699 SEDADEFDFG-------------DTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQL 745

Query: 532 SEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVE 591
           SEVLW MV+ IGL +    G   +VL   F AFA +TVAILL+MEGLSAFLHALRLHWVE
Sbjct: 746 SEVLWTMVIHIGLSVKSLAG--GLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVE 803

Query: 592 FQNKFYSGTGYKLSPFTF 609
           FQNKFYSGTG+K  PF+F
Sbjct: 804 FQNKFYSGTGFKFLPFSF 821


>gi|194097401 ATPase, H+ transporting, lysosomal V0 subunit a1
           isoform a [Homo sapiens]
          Length = 838

 Score =  588 bits (1517), Expect = e-168
 Identities = 310/618 (50%), Positives = 410/618 (66%), Gaps = 27/618 (4%)

Query: 3   FLISYWGEQIGQKIRKITDCFHCHVFPFLQQEEARLGALQQLQQQSQELQEVLGETERFL 62
           F+I + G+Q+  +++KI + F   ++P  +  + R      +  +  +LQ VL +TE   
Sbjct: 227 FIIFFQGDQLKNRVKKICEGFRASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHR 286

Query: 63  SQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHKCLIAEAWCSVRDLPALQEALRD 122
            +VL    + +    ++V KMKA+Y  LN C++  T KCLIAE WC V DL ++Q ALR 
Sbjct: 287 QRVLQAAAKNIRVWFIKVRKMKAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRR 346

Query: 123 SSMEEG--VSAVAHRIPCRDMPPTLIRTNRFTASFQGIVDAYGVGRYQEVNPAPYTIITF 180
            +   G  V ++ +R+     PPT  +TN+FT  FQ IVDAYG+G Y+E+NPAPYTIITF
Sbjct: 347 GTEHSGSTVPSILNRMQTNQTPPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITF 406

Query: 181 PFLFAVMFGDVGHGLLMFLFALAMVLAENRPAVKAAQNEIWQTFFRGRYLLLLMGLFSIY 240
           PFLFAVMFGD GHG+LM LFA+ MVL E+R   +  +NE++ T F GRY++LLMG+FS+Y
Sbjct: 407 PFLFAVMFGDFGHGILMTLFAVWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMY 466

Query: 241 TGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTLDPNVTGVFLGPYPFGI 300
           TG IYN+CFS++ +IF S WSV  M   + W++  L  + +L L+P + GVF GPYPFGI
Sbjct: 467 TGLIYNDCFSKSLNIFGSSWSVRPMFTYN-WTEETLRGNPVLQLNPALPGVFGGPYPFGI 525

Query: 301 DPIWSLAANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTF 360
           DPIW++A N L+FLNSFKMKMSVILG++HM FGV L +FNH++F +   +    +PE+ F
Sbjct: 526 DPIWNIATNKLTFLNSFKMKMSVILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIF 585

Query: 361 LLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSN-RLLYPRQEVVQAT 419
           +  LFGYLV L+ YKW    A  + +APS+LIHFINMFLFS+  S   +LY  Q+ +Q  
Sbjct: 586 MTSLFGYLVILIFYKWTAYDAHTSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCF 645

Query: 420 LVVLALAMVPILLLGTPLHLLHRHRRRLRR--------RPADRQEENKAGLLDLPDASVN 471
           LVV+AL  VP +LL  PL L  ++ RR           R  +   E  A ++     S +
Sbjct: 646 LVVVALLCVPWMLLFKPLVLRRQYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTH 705

Query: 472 GWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQL 531
              +DE   G             + ++HQAIHTIE+CLGC+SNTASYLRLWALSLAHAQL
Sbjct: 706 SEDADEFDFG-------------DTMVHQAIHTIEYCLGCISNTASYLRLWALSLAHAQL 752

Query: 532 SEVLWAMVMRIGLGLGREVGVAAVVLVPIFAAFAVMTVAILLVMEGLSAFLHALRLHWVE 591
           SEVLW MV+ IGL +    G   +VL   F AFA +TVAILL+MEGLSAFLHALRLHWVE
Sbjct: 753 SEVLWTMVIHIGLSVKSLAG--GLVLFFFFTAFATLTVAILLIMEGLSAFLHALRLHWVE 810

Query: 592 FQNKFYSGTGYKLSPFTF 609
           FQNKFYSGTG+K  PF+F
Sbjct: 811 FQNKFYSGTGFKFLPFSF 828


>gi|7661960 Rough Deal homolog, centromere/kinetochore protein [Homo
           sapiens]
          Length = 2209

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 16/49 (32%), Positives = 25/49 (51%)

Query: 236 LFSIYTGFIYNECFSRATSIFPSGWSVAAMANQSGWSDAFLAQHTMLTL 284
           L  +Y   + N C S++TS+F + W   AMA  +  SD  L    +L +
Sbjct: 755 LLLLYIEDLLNRCSSKSTSLFETAWEAKAMAVIACLSDTDLIFDAVLKI 803


>gi|45439367 gap junction protein, gamma 2, 47kDa [Homo sapiens]
          Length = 439

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 26/79 (32%), Positives = 36/79 (45%), Gaps = 15/79 (18%)

Query: 422 VLALAMVPILLLGTPLHLLHR-----HRRRLRRRPADRQEENKAGLLDLPDASVNGWS-- 474
           ++ ++   ++ LG  +H L R      RR LRRRP  R    +A    LP     GW   
Sbjct: 84  IVVISTPSVMYLGYAVHRLARASEQERRRALRRRPGPR----RAPRAHLPPPHA-GWPEP 138

Query: 475 ---SDEEKAGGLDDEEEAE 490
               +EE   GL +EEE E
Sbjct: 139 ADLGEEEPMLGLGEEEEEE 157


>gi|46559747 hypothetical protein LOC399947 [Homo sapiens]
          Length = 197

 Score = 30.8 bits (68), Expect = 3.8
 Identities = 14/40 (35%), Positives = 23/40 (57%)

Query: 418 ATLVVLALAMVPILLLGTPLHLLHRHRRRLRRRPADRQEE 457
           +TLV++ L  V   L+   L   H H+RR+++R   R +E
Sbjct: 60  STLVLIVLVTVIFCLIVLSLSTFHIHKRRMKKRKMQRAQE 99


>gi|130980075 centromere protein J [Homo sapiens]
          Length = 1338

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 5/56 (8%)

Query: 32  QQEEARLGALQQLQ-QQSQELQEVLGETERFLSQVLGRV----LQLLPPGQVQVHK 82
           Q +E +    +QL+ QQ ++LQ ++ E E+ L+ V G+     L LLP  Q Q H+
Sbjct: 148 QLKEVQQKKQEQLKRQQLEQLQRLMEEQEKLLTMVSGQCTLPGLSLLPDDQSQKHR 203


>gi|117414154 sodium channel associated protein 2 isoform b [Homo
           sapiens]
          Length = 939

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 21/91 (23%)

Query: 14  QKIRKITDCFHCHVFPFLQQEEARLGALQ------------QLQQQSQELQEVLGETERF 61
           + IRK+ DC        LQ+++  +  LQ            QL ++S +L EVL + ER 
Sbjct: 731 ETIRKLKDC--------LQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERH 782

Query: 62  LSQVLGRVLQLLPPGQVQVHKMKAVYLALNQ 92
            ++   ++ Q L   +V++ +++  Y  LN+
Sbjct: 783 -NERKEKLKQQLKGKEVELEEIRKAYSTLNR 812


>gi|117414162 sodium channel associated protein 2 isoform a [Homo
           sapiens]
          Length = 1032

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 21/91 (23%)

Query: 14  QKIRKITDCFHCHVFPFLQQEEARLGALQ------------QLQQQSQELQEVLGETERF 61
           + IRK+ DC        LQ+++  +  LQ            QL ++S +L EVL + ER 
Sbjct: 824 ETIRKLKDC--------LQEKDEHIKRLQEKITEIEKCTQEQLDEKSSQLDEVLEKLERH 875

Query: 62  LSQVLGRVLQLLPPGQVQVHKMKAVYLALNQ 92
            ++   ++ Q L   +V++ +++  Y  LN+
Sbjct: 876 -NERKEKLKQQLKGKEVELEEIRKAYSTLNR 905


>gi|71274154 Scm-like with four mbt domains 2 [Homo sapiens]
          Length = 894

 Score = 30.4 bits (67), Expect = 5.0
 Identities = 18/53 (33%), Positives = 29/53 (54%), Gaps = 2/53 (3%)

Query: 444 RRRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKAGGLDDEEEAELVPSEV 496
           RRR RR+    Q++ ++  +D    S  G  S+EE A  +DD+  +E   SE+
Sbjct: 690 RRRKRRKSIFVQKKRRSSAVDFTAGS--GEESEEEDADAMDDDTASEETGSEL 740


>gi|13899255 membrane frizzled-related protein [Homo sapiens]
          Length = 579

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 1/54 (1%)

Query: 482 GLDDEEEAELVPSEVLMHQAIHTIEFCLGCVSNTASYLRLWALSLAHAQLSEVL 535
           G DD     L P   L  + +  +E CLG   NT ++  +W   +   ++ EVL
Sbjct: 449 GSDDNCSGPLFPPPELACEPVQ-VEMCLGLSYNTTAFPNIWVGMITQEEVVEVL 501


>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
           sapiens]
          Length = 631

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 24/100 (24%), Positives = 42/100 (42%), Gaps = 11/100 (11%)

Query: 11  QIGQKIRKITDCFHCHVFPFLQQEEARLGALQQL-----------QQQSQELQEVLGETE 59
           Q+  K R+  +         L++EE +L  L QL           QQ+ +ELQ+ + +  
Sbjct: 443 QLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQS 502

Query: 60  RFLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTH 99
           R L Q   ++ ++    Q     ++A    L Q S +  H
Sbjct: 503 RSLQQAQQQLEEVRQNRQRADEDVEAAQRKLRQASTNVKH 542


>gi|7657345 mitochondrial carrier homolog 1 [Homo sapiens]
          Length = 372

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 11/77 (14%)

Query: 358 LTFLLGLFGYLVFLVIYKWLCVWAARAASAPSILIHFINMFLFSHSPSNRLLYPRQEVVQ 417
           L F +GL  +L+  V++ W C          ++L HFIN +L   S S  L   R     
Sbjct: 250 LGFFVGLIPHLLGDVVFLWGC----------NLLAHFINAYLVDDSFSQALAI-RSYTKF 298

Query: 418 ATLVVLALAMVPILLLG 434
              + +++   P LL+G
Sbjct: 299 VMGIAVSMLTYPFLLVG 315


>gi|7657326 male-enhanced antigen [Homo sapiens]
          Length = 185

 Score = 30.0 bits (66), Expect = 6.5
 Identities = 23/84 (27%), Positives = 37/84 (44%), Gaps = 6/84 (7%)

Query: 452 ADRQEENKAGLLDLPDASVNGWSSDEEKAGGLDDEEEAELVPSEVLMHQAIHTIEFCLGC 511
           AD Q+  +A  L LPD  +     DEE A  L++     + P  V        ++  +  
Sbjct: 94  ADIQDRIQALGLHLPDPPLESEDEDEEGATALNNHSSIPMDPEHV------ELVKRTMAG 147

Query: 512 VSNTASYLRLWALSLAHAQLSEVL 535
           VS  A  +  WA  ++ AQ  +V+
Sbjct: 148 VSLPAPGVPAWAREISDAQWEDVV 171


>gi|149944680 HAUS augmin-like complex, subunit 5 [Homo sapiens]
          Length = 633

 Score = 29.6 bits (65), Expect = 8.5
 Identities = 18/61 (29%), Positives = 29/61 (47%)

Query: 41  LQQLQQQSQELQEVLGETERFLSQVLGRVLQLLPPGQVQVHKMKAVYLALNQCSVSTTHK 100
           L+ L  QSQELQ+  G  +  L ++  +  ++L   Q+     + V L +   S S T  
Sbjct: 355 LKALHDQSQELQDAAGHRQLLLRELQAKQQRILHWRQLVEETQEQVRLLIKGNSASKTRL 414

Query: 101 C 101
           C
Sbjct: 415 C 415


>gi|5453726 leucine rich repeat (in FLII) interacting protein 2
           isoform 1 [Homo sapiens]
          Length = 721

 Score = 29.6 bits (65), Expect = 8.5
 Identities = 22/61 (36%), Positives = 30/61 (49%), Gaps = 6/61 (9%)

Query: 440 LHRHRRRLRRRPADRQEE----NKAGLLDLPDASVNGWSSDEEKAGGLD--DEEEAELVP 493
           L   R  LR   AD QE      K GL+ +PD + NG  S E  AG +    +E A+++ 
Sbjct: 500 LRNERDMLREELADLQETVKTGEKHGLVIIPDGTPNGDVSHEPVAGAITVVSQEAAQVLE 559

Query: 494 S 494
           S
Sbjct: 560 S 560


>gi|7705268 family with sequence similarity 8, member A1 [Homo
           sapiens]
          Length = 413

 Score = 29.6 bits (65), Expect = 8.5
 Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 17/128 (13%)

Query: 308 ANHLSFLNSFKMKMSVILGVVHMAFGVVLGVFNHVHFGQRHRLLLETLPELTFLLGLFGY 367
           A  + F   F +K +++L ++H++     G+ +   F   +  ++E + E T +  L   
Sbjct: 252 AEMVDFFILFFIKATIVLSIMHLS-----GIKDISKFAMHY--IIEEIDEDTSMEDLQKM 304

Query: 368 LVFLVIYKWL-------CVWAARAASAPSILIHFINMFLFSH---SPSNRLLYPRQEVVQ 417
           +V  +IY+ L       C+W A  A+    L+    +   +    +PS  L+ P   V  
Sbjct: 305 MVVALIYRLLVCFYEIICIWGAGGATPGKFLLGLRVVTCDTSVLIAPSRVLVIPSSNVSI 364

Query: 418 ATLVVLAL 425
            T  + AL
Sbjct: 365 TTSTIRAL 372


>gi|157042792 coiled-coil domain containing 64B [Homo sapiens]
          Length = 508

 Score = 29.6 bits (65), Expect = 8.5
 Identities = 17/46 (36%), Positives = 27/46 (58%), Gaps = 5/46 (10%)

Query: 445 RRLRRRPADRQEENKAGLLDLPDASVNGWSSDEEKAGGLDDEEEAE 490
           RRL+RR ++ +EE++     L DA V+  S   E A  LDD ++ +
Sbjct: 270 RRLQRRVSELEEESR-----LQDADVSAASLQSELAHSLDDGDQGQ 310


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.139    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,110,602
Number of Sequences: 37866
Number of extensions: 952992
Number of successful extensions: 4550
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 4498
Number of HSP's gapped (non-prelim): 26
length of query: 614
length of database: 18,247,518
effective HSP length: 108
effective length of query: 506
effective length of database: 14,157,990
effective search space: 7163942940
effective search space used: 7163942940
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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