Guide to the Human Genome
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Search of human proteins with 51093863

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|51093863 hypothetical protein LOC64855 isoform 1 [Homo
sapiens]
         (746 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|51093863 hypothetical protein LOC64855 isoform 1 [Homo sapiens]   1500   0.0  
gi|79750824 hypothetical protein LOC64855 isoform 2 [Homo sapiens]   1465   0.0  
gi|16757970 niban protein isoform 2 [Homo sapiens]                    444   e-124
gi|148664236 B-cell novel protein 1 isoform b [Homo sapiens]          213   5e-55
gi|31542207 B-cell novel protein 1 isoform a [Homo sapiens]           213   5e-55
gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo ...    47   5e-05
gi|112421108 capicua homolog [Homo sapiens]                            47   6e-05
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]                47   8e-05
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]                47   8e-05
gi|7662236 TSC22 domain family, member 2 [Homo sapiens]                45   2e-04
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 45   2e-04
gi|110349719 titin isoform N2-A [Homo sapiens]                         44   5e-04
gi|113204604 aristaless-like homeobox 3 [Homo sapiens]                 44   5e-04
gi|20070193 nuclear receptor subfamily 5, group A, member 1 [Hom...    44   5e-04
gi|13129104 coiled-coil domain containing 86 [Homo sapiens]            44   5e-04
gi|150170670 piccolo isoform 2 [Homo sapiens]                          44   7e-04
gi|150378539 piccolo isoform 1 [Homo sapiens]                          44   7e-04
gi|33356148 formin-like 1 [Homo sapiens]                               44   7e-04
gi|153792074 proline rich 12 [Homo sapiens]                            44   7e-04
gi|55741677 SET domain containing 1A [Homo sapiens]                    43   0.001
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   0.002
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       42   0.002
gi|62000702 diacylglycerol kinase kappa [Homo sapiens]                 42   0.002
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    42   0.002
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]               42   0.002
gi|38787970 tensin like C1 domain containing phosphatase isoform...    42   0.003
gi|38787957 tensin like C1 domain containing phosphatase isoform...    42   0.003
gi|38787941 tensin like C1 domain containing phosphatase isoform...    42   0.003
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho...    42   0.003
gi|163965366 nascent polypeptide-associated complex alpha subuni...    42   0.003

>gi|51093863 hypothetical protein LOC64855 isoform 1 [Homo sapiens]
          Length = 746

 Score = 1500 bits (3884), Expect = 0.0
 Identities = 746/746 (100%), Positives = 746/746 (100%)

Query: 1   MGDVLSTHLDDARRQHIAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLW 60
           MGDVLSTHLDDARRQHIAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLW
Sbjct: 1   MGDVLSTHLDDARRQHIAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLW 60

Query: 61  RKVPLDERIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSA 120
           RKVPLDERIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSA
Sbjct: 61  RKVPLDERIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSA 120

Query: 121 GYKILTSVDQYLELIGNSLPGTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQ 180
           GYKILTSVDQYLELIGNSLPGTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQ
Sbjct: 121 GYKILTSVDQYLELIGNSLPGTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQ 180

Query: 181 DKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNL 240
           DKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNL
Sbjct: 181 DKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNL 240

Query: 241 VMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPA 300
           VMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPA
Sbjct: 241 VMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPA 300

Query: 301 MQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTE 360
           MQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTE
Sbjct: 301 MQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTE 360

Query: 361 VRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESLRLDGLQQR 420
           VRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESLRLDGLQQR
Sbjct: 361 VRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESLRLDGLQQR 420

Query: 421 FDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKY 480
           FDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKY
Sbjct: 421 FDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKY 480

Query: 481 DYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEV 540
           DYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEV
Sbjct: 481 DYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEV 540

Query: 541 VLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGG 600
           VLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGG
Sbjct: 541 VLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGG 600

Query: 601 SPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQG 660
           SPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQG
Sbjct: 601 SPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQG 660

Query: 661 LRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETG 720
           LRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETG
Sbjct: 661 LRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETG 720

Query: 721 EQVSSPSSHPALHTTTEDSAGVQTEF 746
           EQVSSPSSHPALHTTTEDSAGVQTEF
Sbjct: 721 EQVSSPSSHPALHTTTEDSAGVQTEF 746


>gi|79750824 hypothetical protein LOC64855 isoform 2 [Homo sapiens]
          Length = 733

 Score = 1465 bits (3792), Expect = 0.0
 Identities = 728/730 (99%), Positives = 729/730 (99%)

Query: 17  IAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLWRKVPLDERIVFSGNLF 76
           + EKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLWRKVPLDERIVFSGNLF
Sbjct: 4   MGEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLWRKVPLDERIVFSGNLF 63

Query: 77  QHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSAGYKILTSVDQYLELIG 136
           QHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSAGYKILTSVDQYLELIG
Sbjct: 64  QHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSAGYKILTSVDQYLELIG 123

Query: 137 NSLPGTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCIRHCNN 196
           NSLPGTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCIRHCNN
Sbjct: 124 NSLPGTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTEAEQDKWQAVLQDCIRHCNN 183

Query: 197 GIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNLVMEELGPELKAELGPR 256
           GIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNLVMEELGPELKAELGPR
Sbjct: 184 GIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQILSNLVMEELGPELKAELGPR 243

Query: 257 LKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPAMQAVIRTDMDQIITSK 316
           LKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPAMQAVIRTDMDQIITSK
Sbjct: 244 LKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQVQPAMQAVIRTDMDQIITSK 303

Query: 317 EHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNV 376
           EHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNV
Sbjct: 304 EHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQGFTEVRDVFFKEVTDMNLNV 363

Query: 377 INEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESLRLDGLQQRFDVSSTSVFKQRAQIH 436
           INEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESLRLDGLQQRFDVSSTSVFKQRAQIH
Sbjct: 364 INEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESLRLDGLQQRFDVSSTSVFKQRAQIH 423

Query: 437 MREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKYDYDSSSVRKRFFREAL 496
           MREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKYDYDSSSVRKRFFREAL
Sbjct: 424 MREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLERVLKKYDYDSSSVRKRFFREAL 483

Query: 497 LQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEA 556
           LQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEA
Sbjct: 484 LQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVENTYEEVVLQTVMKDILQAVKEA 543

Query: 557 AVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKR 616
           AVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKR
Sbjct: 544 AVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKR 603

Query: 617 RRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGA 676
           RRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGA
Sbjct: 604 RRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGA 663

Query: 677 PAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTT 736
           PAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTT
Sbjct: 664 PAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTT 723

Query: 737 EDSAGVQTEF 746
           EDSAGVQTEF
Sbjct: 724 EDSAGVQTEF 733


>gi|16757970 niban protein isoform 2 [Homo sapiens]
          Length = 928

 Score =  444 bits (1142), Expect = e-124
 Identities = 273/769 (35%), Positives = 409/769 (53%), Gaps = 46/769 (5%)

Query: 1   MGDVLSTHLDDARRQHIAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLW 60
           MG   S+ LD+ +  +I  KT   +  F  +Y  QY VA  N +R E+E      +Q L 
Sbjct: 1   MGGSASSQLDEGKCAYIRGKTEAAIKNFSPYYSRQYSVAFCNHVRTEVEQQRDLTSQFLK 60

Query: 61  RKVPLDE-RIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINS 119
            K PL    I++   L Q  ED KKW+ R+ +V ++Y +  YENK AY+R   P+  I  
Sbjct: 61  TKPPLAPGTILYEAELSQFSEDIKKWKERYVVVKNDYAVESYENKEAYQRGAAPKCRILP 120

Query: 120 AGYKILTSVDQYLELIGNSLPGTTA---KSGSAPILKCPTQFPLILWHPYARHYYFCMMT 176
           AG K+LTS D+Y  L     P   A   K  + P +  P +FP+ LW P+ RH YFC   
Sbjct: 121 AGGKVLTSEDEYNLLSDRHFPDPLASSEKENTQPFVVLPKEFPVYLWQPFFRHGYFCFHE 180

Query: 177 EAEQDKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQI 236
            A+Q ++ A+L DC+RH N+   +    E  AF +A++ +RQ K  YG+WEM+ G+E+QI
Sbjct: 181 AADQKRFSALLSDCVRHLNHDYMKQMTFEAQAFLEAVQFFRQEKGHYGSWEMITGDEIQI 240

Query: 237 LSNLVMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQ 296
           LSNLVMEEL P L+ +L P++KGK  +R+R W+ + +  Y +V  Q       +  + + 
Sbjct: 241 LSNLVMEELLPTLQTDLLPKMKGKKNDRKRTWLGLLEEAYTLVQHQVSEGLSALKEECRA 300

Query: 297 VQPAMQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQ 356
           +   ++  IR+DMDQI+ SK +L  KI+A +   AE      VQP++ SILE LM P S 
Sbjct: 301 LTKGLEGTIRSDMDQIVNSKNYLIGKIKAMVAQPAEKSCLESVQPFLASILEELMGPVSS 360

Query: 357 GFTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESL--RL 414
           GF+EVR +F KEV +++ N        +L E++++L  L  H +KM+ CY K+  L  RL
Sbjct: 361 GFSEVRVLFEKEVNEVSQNFQTTKDSVQLKEHLDRLMNLPLHSVKMEPCYTKVNLLHERL 420

Query: 415 DGLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLE 474
             L+ RF      +  QR Q +M+E M+NAV+TFE LL   L    +K  +  +I++V  
Sbjct: 421 QDLKSRFRFPHIDLVVQRTQNYMQELMENAVFTFEQLLSPHLQGEASKTAV--AIEKVKL 478

Query: 475 RVLKKYDYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVE 534
           RVLK+YDYDSS++RK+ F+EAL+QI++P + K LA TCK EL ++++ IF D    I VE
Sbjct: 479 RVLKQYDYDSSTIRKKIFQEALVQITLPTVQKALASTCKPELQKYEQFIFADHTNMIHVE 538

Query: 535 NTYEEVVLQTVMKDILQAVKEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYS 594
           N YEE++ Q ++ + L+ +KEAA+ +KHNL+ D+M + +   ++  L +  P     + S
Sbjct: 539 NVYEEILHQILLDETLKVIKEAAILKKHNLFEDNMALPSE--SVSSLTDLKPPTGSNQAS 596

Query: 595 NSGGGGSPSPSTPESATL-------SEKRRRAKQVVSVVQDEEVGLPFEASPE------- 640
            +    +  P    S TL       SE+ ++ +   S+ + E + LP  + P        
Sbjct: 597 PARRASAILPGVLGSETLSNEVFQESEEEKQPEVPSSLAKGESLSLPGPSPPPDGTEQVI 656

Query: 641 ----SPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPAS 696
                 P  +P    +  GL   G         G L +  PA E P+P  A    S    
Sbjct: 657 ISRVDDPVVNPVATEDTAGL--PGTCSSELEFGGTLEDEEPAQEEPEPITA----SGSLK 710

Query: 697 PLQHLLPGKA---VDLGPPKPSD---------QETGEQVSSPSSHPALH 733
            L+ LL       VD  P    D         +   E+   PS   A+H
Sbjct: 711 ALRKLLTASVEVPVDSAPVMEEDTNGESHVPQENEEEEEKEPSQAAAIH 759



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 28/103 (27%), Positives = 41/103 (39%), Gaps = 6/103 (5%)

Query: 608 ESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPP 667
           +SA + E+    +  V    +EE     E  P       PD   E   +  +  +P  P 
Sbjct: 725 DSAPVMEEDTNGESHVPQENEEEE----EKEPSQAAAIHPDNCEESE-VSEREAQPPCPE 779

Query: 668 PAGPLLNGAPAGESP-QPKAAPEASSPPASPLQHLLPGKAVDL 709
             G  L G P   SP  P A+   +  P  P++  LPG+A  L
Sbjct: 780 AHGEELGGFPEVGSPASPPASGGLTEEPLGPMEGELPGEACTL 822


>gi|148664236 B-cell novel protein 1 isoform b [Homo sapiens]
          Length = 651

 Score =  213 bits (542), Expect = 5e-55
 Identities = 152/560 (27%), Positives = 255/560 (45%), Gaps = 6/560 (1%)

Query: 1   MGDVLSTHLDDARRQHIAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLW 60
           MG   S+ LD  +RQH+  +   +L  FL  Y  Q   ++   +  E+ G   P    L 
Sbjct: 32  MGGRPSSPLDKQQRQHLRGQVDTLLRNFLPCYRGQLAASVLRQISREL-GPQEPTGSQLL 90

Query: 61  RKVPLDERIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSA 120
           R   L       G L Q +    +W+  F ++  +  L  + +K  YE            
Sbjct: 91  RSKKLPRVREHRGPLTQLRGHPPRWQPIFCVLRGDGRLEWFSHKEEYENGGHCLGSTALT 150

Query: 121 GYKILTSVDQYLELIGNSLP---GTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTE 177
           GY +LTS  +YL L+    P   G   +     +L+ P  FPL L HP+ RH  F   T 
Sbjct: 151 GYTLLTSQREYLRLLDALCPESLGDHTQEEPDSLLEVPVSFPLFLQHPFRRHLCFSAATR 210

Query: 178 AEQDKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQIL 237
             Q  W+  LQ  IR     +         AF DA+R+YRQ +  +G  ++  G++ ++L
Sbjct: 211 EAQHAWRLALQGGIRLQGTVLQRSQAPAARAFLDAVRLYRQHQGHFGDDDVTLGSDAEVL 270

Query: 238 SNLVMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQV 297
           + ++M E  P L+A+  P L+G  + R   W ++ DAV+  V   A A       +  ++
Sbjct: 271 TAVLMREQLPALRAQTLPGLRGAGRARAWAWTELLDAVHAAVLAGASAGLCAFQPEKDEL 330

Query: 298 QPAMQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQG 357
             +++  IR D+DQ++  +  +A ++R  I    E C+R  V P +P +++ L+      
Sbjct: 331 LASLEKTIRPDVDQLLRQRARVAGRLRTDIRGPLESCLRREVDPQLPRVVQTLLRTVEAS 390

Query: 358 FTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESL--RLD 415
              VR +  + +  ++  +       +L   +     + +    MQ+CY + E    RL 
Sbjct: 391 LEAVRTLLAQGMDRLSHRLRQSPSGTRLRREVYSFGEMPWDLALMQTCYREAERSRGRLG 450

Query: 416 GLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLER 475
            L   F           AQ   ++ M +AV TF  L  Q L      ++  + ++RV  R
Sbjct: 451 QLAAPFGFLGMQSLVFGAQDLAQQLMADAVATFLQLADQCLTTALNCDQAAQRLERVRGR 510

Query: 476 VLKKYDYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVEN 535
           VLKK+  DS   ++RF R   L I +PF+L +L P CK ELP F+  +    ++ +  E 
Sbjct: 511 VLKKFKSDSGLAQRRFIRGWGLCIFLPFVLSQLEPGCKKELPEFEGDVLAVGSQALTTEG 570

Query: 536 TYEEVVLQTVMKDILQAVKE 555
            YE+V+   +++ I Q +K+
Sbjct: 571 IYEDVIRGCLLQRIDQELKK 590


>gi|31542207 B-cell novel protein 1 isoform a [Homo sapiens]
          Length = 697

 Score =  213 bits (542), Expect = 5e-55
 Identities = 152/560 (27%), Positives = 255/560 (45%), Gaps = 6/560 (1%)

Query: 1   MGDVLSTHLDDARRQHIAEKTGKILTEFLQFYEDQYGVALFNSMRHEIEGTGLPQAQLLW 60
           MG   S+ LD  +RQH+  +   +L  FL  Y  Q   ++   +  E+ G   P    L 
Sbjct: 32  MGGRPSSPLDKQQRQHLRGQVDTLLRNFLPCYRGQLAASVLRQISREL-GPQEPTGSQLL 90

Query: 61  RKVPLDERIVFSGNLFQHQEDSKKWRNRFSLVPHNYGLVLYENKAAYERQVPPRAVINSA 120
           R   L       G L Q +    +W+  F ++  +  L  + +K  YE            
Sbjct: 91  RSKKLPRVREHRGPLTQLRGHPPRWQPIFCVLRGDGRLEWFSHKEEYENGGHCLGSTALT 150

Query: 121 GYKILTSVDQYLELIGNSLP---GTTAKSGSAPILKCPTQFPLILWHPYARHYYFCMMTE 177
           GY +LTS  +YL L+    P   G   +     +L+ P  FPL L HP+ RH  F   T 
Sbjct: 151 GYTLLTSQREYLRLLDALCPESLGDHTQEEPDSLLEVPVSFPLFLQHPFRRHLCFSAATR 210

Query: 178 AEQDKWQAVLQDCIRHCNNGIPEDSKVEGPAFTDAIRMYRQSKELYGTWEMLCGNEVQIL 237
             Q  W+  LQ  IR     +         AF DA+R+YRQ +  +G  ++  G++ ++L
Sbjct: 211 EAQHAWRLALQGGIRLQGTVLQRSQAPAARAFLDAVRLYRQHQGHFGDDDVTLGSDAEVL 270

Query: 238 SNLVMEELGPELKAELGPRLKGKPQERQRQWIQISDAVYHMVYEQAKARFEEVLSKVQQV 297
           + ++M E  P L+A+  P L+G  + R   W ++ DAV+  V   A A       +  ++
Sbjct: 271 TAVLMREQLPALRAQTLPGLRGAGRARAWAWTELLDAVHAAVLAGASAGLCAFQPEKDEL 330

Query: 298 QPAMQAVIRTDMDQIITSKEHLASKIRAFILPKAEVCVRNHVQPYIPSILEALMVPTSQG 357
             +++  IR D+DQ++  +  +A ++R  I    E C+R  V P +P +++ L+      
Sbjct: 331 LASLEKTIRPDVDQLLRQRARVAGRLRTDIRGPLESCLRREVDPQLPRVVQTLLRTVEAS 390

Query: 358 FTEVRDVFFKEVTDMNLNVINEGGIDKLGEYMEKLSRLAYHPLKMQSCYEKMESL--RLD 415
              VR +  + +  ++  +       +L   +     + +    MQ+CY + E    RL 
Sbjct: 391 LEAVRTLLAQGMDRLSHRLRQSPSGTRLRREVYSFGEMPWDLALMQTCYREAERSRGRLG 450

Query: 416 GLQQRFDVSSTSVFKQRAQIHMREQMDNAVYTFETLLHQELGKGPTKEELCKSIQRVLER 475
            L   F           AQ   ++ M +AV TF  L  Q L      ++  + ++RV  R
Sbjct: 451 QLAAPFGFLGMQSLVFGAQDLAQQLMADAVATFLQLADQCLTTALNCDQAAQRLERVRGR 510

Query: 476 VLKKYDYDSSSVRKRFFREALLQISIPFLLKKLAPTCKSELPRFQELIFEDFARFILVEN 535
           VLKK+  DS   ++RF R   L I +PF+L +L P CK ELP F+  +    ++ +  E 
Sbjct: 511 VLKKFKSDSGLAQRRFIRGWGLCIFLPFVLSQLEPGCKKELPEFEGDVLAVGSQALTTEG 570

Query: 536 TYEEVVLQTVMKDILQAVKE 555
            YE+V+   +++ I Q +K+
Sbjct: 571 IYEDVIRGCLLQRIDQELKK 590


>gi|239752265 PREDICTED: hypothetical protein XP_002348186 [Homo
           sapiens]
          Length = 225

 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 48/164 (29%), Positives = 67/164 (40%), Gaps = 25/164 (15%)

Query: 567 DSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVV 626
           DS+V+ +  P+  +L  G+P D     S S     P P +P+S  L   R     V    
Sbjct: 26  DSVVLPSRSPDSVVLPPGSP-DSVVLPSRSPDSVVPPPGSPDSVVLPP-RSPDSVVPPPG 83

Query: 627 QDEEVGLPFEASPES--PPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQP 684
             + V LP   SP+S  PPP SPD V               PPP      G+P      P
Sbjct: 84  SPDSVVLP-PRSPDSVVPPPRSPDSVV--------------PPP------GSPDSVVLPP 122

Query: 685 KAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSS 728
           ++      PP SP   +LP ++ D   P     ++G +  SP S
Sbjct: 123 RSPDSVVPPPGSPDSVVLPPRSPDSVVPPARSPDSGGRAGSPRS 166


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 46/184 (25%), Positives = 67/184 (36%), Gaps = 21/184 (11%)

Query: 576 PNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAK-----QVVSVVQDEE 630
           P +  +A+GAP   G   + SG G    P+ P    + +     K     QV  ++    
Sbjct: 776 PAVQFIAQGAP--GGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLP 833

Query: 631 VGLPFEASPESPP------PASPDGVTEIRGLLAQG-------LRPESPPPAGPLLNGAP 677
             L    +P   P      P+ P   T IR  L  G       L   +P P  P+L   P
Sbjct: 834 QQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVP 893

Query: 678 AGESPQPKAAPEASSPPASPLQHLLPGKA-VDLGPPKPSDQETGEQVSSPSSHPALHTTT 736
           +   P+ ++     +PP      LLPGK  V L  P  S +  G     P   P      
Sbjct: 894 SAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPV 953

Query: 737 EDSA 740
           ++ A
Sbjct: 954 QNGA 957



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 33/104 (31%), Positives = 42/104 (40%), Gaps = 19/104 (18%)

Query: 603 SPSTPE-SATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPP-------PASPDGVTEIR 654
           +PS P+ S   SE ++ A   V+  Q +E       + E PP       P  P G T   
Sbjct: 45  APSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGAT--- 101

Query: 655 GLLAQGLRPESPPPAGPL-LNGAPAGESPQPKAAPEASSPPASP 697
                   PESP P  P  L    +G+ P P    EAS PP  P
Sbjct: 102 -------CPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEP 138



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 34/121 (28%), Positives = 47/121 (38%), Gaps = 19/121 (15%)

Query: 607  PESATLSEKRRRAKQVVSVVQDEEVGLPFEASP--ESPPPASPDGVTEIRGLLAQGLRPE 664
            P    L  K R  +Q +      +   P E  P  E+P P  P   T      A    P 
Sbjct: 1502 PSKVCLQLKIREVRQKIM-----QAATPTEQPPGAEAPLPVPPPTGT------AAAPAP- 1549

Query: 665  SPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVS 724
            +P PAG     +P+ +S   +AAP    PP S      PG+    G P+PS    G   +
Sbjct: 1550 TPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESG-----PGQPGWEGAPQPSPPPPGPSTA 1604

Query: 725  S 725
            +
Sbjct: 1605 A 1605


>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
          Length = 1240

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 40/138 (28%), Positives = 50/138 (36%), Gaps = 15/138 (10%)

Query: 585 APIDWGEEYSNSGGGGSPSPST----PESATLSEKRRRAKQVVSVVQDEEVGLPFEASPE 640
           A +D  +  S+     +P PS     P +A   E    A+    +   +   L  +AS  
Sbjct: 362 ANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTP 421

Query: 641 SPPPASPDGVTEIRGLLAQGLRPESPPPAGPL----LNGAPAGESPQPKAAPEASSPPAS 696
            PPP  P        L      P  PPP  PL        P    P P     A +PPA 
Sbjct: 422 PPPPPPPL-------LPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAP 474

Query: 697 PLQHLLPGKAVDLGPPKP 714
           PL   LPG    L PP P
Sbjct: 475 PLPPPLPGSCEFLPPPPP 492



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 15/89 (16%)

Query: 637 ASPESPPPASPDGVTEIRGLLAQGLRPESP--------PPAGPL---LNGAPAGESPQPK 685
           +S E PPP  P  +  +         P  P        PPA PL   L G+     P P 
Sbjct: 433 SSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPP 492

Query: 686 AAPEASSPPASPLQHLLPGKAVDLGPPKP 714
             P    PP  P   LLPG  +  GPP P
Sbjct: 493 PLPGLGCPPPPP--PLLPG--MGWGPPPP 517


>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
          Length = 1249

 Score = 46.6 bits (109), Expect = 8e-05
 Identities = 40/138 (28%), Positives = 50/138 (36%), Gaps = 15/138 (10%)

Query: 585 APIDWGEEYSNSGGGGSPSPST----PESATLSEKRRRAKQVVSVVQDEEVGLPFEASPE 640
           A +D  +  S+     +P PS     P +A   E    A+    +   +   L  +AS  
Sbjct: 362 ANLDQSQRGSSPQNTTTPKPSVEGQQPAAAAACEPVDHAQSESILKVSQPRALEQQASTP 421

Query: 641 SPPPASPDGVTEIRGLLAQGLRPESPPPAGPL----LNGAPAGESPQPKAAPEASSPPAS 696
            PPP  P        L      P  PPP  PL        P    P P     A +PPA 
Sbjct: 422 PPPPPPPL-------LPGSSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAP 474

Query: 697 PLQHLLPGKAVDLGPPKP 714
           PL   LPG    L PP P
Sbjct: 475 PLPPPLPGSCEFLPPPPP 492



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 15/89 (16%)

Query: 637 ASPESPPPASPDGVTEIRGLLAQGLRPESP--------PPAGPL---LNGAPAGESPQPK 685
           +S E PPP  P  +  +         P  P        PPA PL   L G+     P P 
Sbjct: 433 SSAEPPPPPPPPPLPSVGAKALPTAPPPPPLPGLGAMAPPAPPLPPPLPGSCEFLPPPPP 492

Query: 686 AAPEASSPPASPLQHLLPGKAVDLGPPKP 714
             P    PP  P   LLPG  +  GPP P
Sbjct: 493 PLPGLGCPPPPP--PLLPG--MGWGPPPP 517


>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
          Length = 780

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 45/165 (27%), Positives = 62/165 (37%), Gaps = 32/165 (19%)

Query: 602 PSPSTPESATLSEKRRRAKQVVSVVQDEEVGLP-------------FEASPESPPPASPD 648
           P+P+ P+S ++ + +     V   V      LP               A P  P  A P 
Sbjct: 261 PTPAQPQSFSVGQPQPPPPPVGGAVAQSSAPLPPFPGAATGPQPMMAAAQPSQPQGAGPG 320

Query: 649 GVT--EIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGK- 705
           G T       LAQ      PP  GP + GAPA + PQ  A P+   PP     HLLP + 
Sbjct: 321 GQTLPPTNVTLAQPAM-SLPPQPGPAV-GAPAAQQPQQFAYPQPQIPPG----HLLPVQP 374

Query: 706 ----------AVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDSA 740
                        L PP P+   +    +SP++   L   T  +A
Sbjct: 375 SGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVGTGQNA 419


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 29/83 (34%), Positives = 35/83 (42%), Gaps = 7/83 (8%)

Query: 632 GLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEAS 691
           GLP    P +PP   P G+  +RG L + L P  PPP      G P G  P P       
Sbjct: 429 GLPPGPPPGAPPFLRPPGMPGLRGPLPR-LLPPGPPP------GRPPGPPPGPPPGLPPG 481

Query: 692 SPPASPLQHLLPGKAVDLGPPKP 714
            PP  P   L P     + PP+P
Sbjct: 482 PPPRGPPPRLPPPAPPGIPPPRP 504



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 26/92 (28%), Positives = 33/92 (35%), Gaps = 2/92 (2%)

Query: 634 PFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSP 693
           P    P  PPP  P G+    G   +G  P  PPPA P +     G    P   P   +P
Sbjct: 462 PPPGRPPGPPPGPPPGLPP--GPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAP 519

Query: 694 PASPLQHLLPGKAVDLGPPKPSDQETGEQVSS 725
           P       LP   V   PP    +   +  S+
Sbjct: 520 PGLFPPAPLPNPGVLSAPPNLIQRPKADDTSA 551


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 8/97 (8%)

Query: 625   VVQDEEVGLPFEASPESPPPASPDGVTEI----RGLLAQGLRPESPPPAGPLLNGAPAGE 680
             VV +++V +P    PE+PPP  P+   E+    +  +    +PE PP   P +  A   E
Sbjct: 10504 VVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPE 10563

Query: 681   SPQPKAAP--EASSPPASP--LQHLLPGKAVDLGPPK 713
                P+A P    S PP  P   + ++P K V   PPK
Sbjct: 10564 KKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPK 10600



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 32/125 (25%), Positives = 47/125 (37%), Gaps = 9/125 (7%)

Query: 626  VQDEEVGLPFEASPESPPPASPD---GVTEIRGLLAQGLRPESPPPAGPLL--NGAPAGE 680
            V +E++ +P     E+PP   P+   GV     +     R ESPPPA P +     P   
Sbjct: 9352 VPEEKIPVPVAKKKEAPPAKVPEVQKGVVTEEKITIVTQREESPPPAVPEIPKKKVPEER 9411

Query: 681  SPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDSA 740
             P P+   E   PP  P     P     +  P P      ++   P +  +  T  E+  
Sbjct: 9412 KPVPRKEEEVPPPPKVPALPKKPVPEEKVAVPVP----VAKKAPPPRAEVSKKTVVEEKR 9467

Query: 741  GVQTE 745
             V  E
Sbjct: 9468 FVAEE 9472



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 29/86 (33%), Positives = 40/86 (46%), Gaps = 12/86 (13%)

Query: 625   VVQDEEVGLPFEASPESPPPASPD----GVTEIRGLLAQGLRPESPPPA------GPLLN 674
             VV +++V +P    PE PP   P+     V E +   A   +PESPPP          L 
Sbjct: 10616 VVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALE 10675

Query: 675   GAPAG--ESPQPKAAPEASSPPASPL 698
               PA   E P+P A P+ + PP  P+
Sbjct: 10676 EPPAEVVEEPEPAAPPQVTVPPKKPV 10701



 Score = 37.0 bits (84), Expect = 0.067
 Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 8/77 (10%)

Query: 625   VVQDEEVGLPF--EASPESPPPASPDGVTEI--RGLLAQGLRPESPPPAGPLLNGAPAGE 680
             +  +EE  +P   E  PE PPPA P+   +I     +    +PE+PPP  P     P   
Sbjct: 10816 IAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEP----EPEKV 10871

Query: 681   SPQPKAAPEASSPPASP 697
               +PK  P    PP +P
Sbjct: 10872 IEKPKLKPRPPPPPPAP 10888



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 40/160 (25%), Positives = 63/160 (39%), Gaps = 40/160 (25%)

Query: 602   PSPSTPESATLSEKR----RRAKQVVS----------------VVQDEEVGLPFEASPES 641
             P P+ P   T+  K+    ++A  VV+                VV +++V L     PE+
Sbjct: 10685 PEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA 10744

Query: 642   PPPASPDGVTEI--RGLLAQGLRPESPP------PAGPLLNGAPA------GESPQPKAA 687
             PP   P+   E+     +A   +PE PP      P  P+L   PA       ESP P+  
Sbjct: 10745 PPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVY 10804

Query: 688   PEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPS 727
              E      +P + + P +      P P  +E   +V  P+
Sbjct: 10805 EEPEE--IAPEEEIAPEEE----KPVPVAEEEEPEVPPPA 10838



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 26/90 (28%), Positives = 36/90 (40%), Gaps = 20/90 (22%)

Query: 624   SVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQ 683
             + V +++V       PESPPP  P+   E+         PE   PA P     P      
Sbjct: 10559 AAVPEKKVPEAIPPKPESPPPEVPEAPKEV--------VPEKKVPAAP-----PKKPEVT 10605

Query: 684   PKAAPEASSPPASPLQHLLPGKAVDLGPPK 713
             P   PEA        + ++P K V + PPK
Sbjct: 10606 PVKVPEAP-------KEVVPEKKVPVPPPK 10628



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 11/89 (12%)

Query: 643  PPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLL 702
            P    + VTE +  +A   R E PPP  P L   PA E   P   P+   PPA  +  + 
Sbjct: 9262 PEVQKEIVTEEKIHVAISKRVE-PPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEV- 9319

Query: 703  PGKAVDLGPPKPSDQETGEQVSSPSSHPA 731
                    P KP  +E  + V  P   PA
Sbjct: 9320 --------PKKPVPEEK-KPVPVPKKEPA 9339



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 26/117 (22%), Positives = 44/117 (37%), Gaps = 10/117 (8%)

Query: 602   PSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGL 661
             P P   E   +    +R +++    +  E+     A P   P   P    E++ +    +
Sbjct: 10981 PPPKPVEEVEVPTVTKRERKIPEPTKVPEIK---PAIPLPAPEPKPKPEAEVKTIKPPPV 11037

Query: 662   RPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQE 718
              PE  P A P +     G+  + KA  E ++ P  P+      K V    P P + E
Sbjct: 11038 EPEPTPIAAP-VTVPVVGKKAEAKAPKEEAAKPKGPI------KGVPKKTPSPIEAE 11087


>gi|113204604 aristaless-like homeobox 3 [Homo sapiens]
          Length = 343

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 37/106 (34%), Positives = 44/106 (41%), Gaps = 2/106 (1%)

Query: 628 DEEVGLPFEASPESPP-PASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKA 686
           D E   PF   P   P  AS D     +G  A        PP GP L   PA    +P  
Sbjct: 2   DPEHCAPFRVGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFPACGPLEPYL 61

Query: 687 APEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPAL 732
            PE + PPA  LQ L PG A++ G       E  E+ S  +S P L
Sbjct: 62  -PEPAKPPAKYLQDLGPGPALNGGHFYEGPAEAEEKTSKAASFPQL 106


>gi|20070193 nuclear receptor subfamily 5, group A, member 1 [Homo
           sapiens]
          Length = 461

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 39/107 (36%), Positives = 48/107 (44%), Gaps = 13/107 (12%)

Query: 615 KRRRAKQVVSVVQDEEVGLPFEASPES----PPPASPDGVT--EIRGLLAQGLRPESPPP 668
           KR RA +     Q    G   E  P      PPP +PD V    + G   +GL   + PP
Sbjct: 100 KRDRALKQQKKAQIRANGFKLETGPPMGVPPPPPPAPDYVLPPSLHGPEPKGLA--AGPP 157

Query: 669 AGPLLN-GAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKP 714
           AGPL + GAPA     P A P A  P A  L    PG+A+    P+P
Sbjct: 158 AGPLGDFGAPA----LPMAVPGAHGPLAGYLYPAFPGRAIKSEYPEP 200


>gi|13129104 coiled-coil domain containing 86 [Homo sapiens]
          Length = 360

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 40/126 (31%), Positives = 51/126 (40%), Gaps = 22/126 (17%)

Query: 600 GSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESP-PPASPDGVTEIRGLLA 658
           G   P +PES T   + RRA             + FE++PE    P SP  V   R  L 
Sbjct: 12  GGLRPESPESLTSVSRTRRAL------------VEFESNPEETREPGSPPSVQ--RAGLG 57

Query: 659 QGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHL-LPGKAVDLGP------ 711
              RP    P  P L      ESPQ +  P A+SP      HL  P +  +  P      
Sbjct: 58  SPERPPKTSPGSPRLQQGAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEYSPESPRCQ 117

Query: 712 PKPSDQ 717
           PKPS++
Sbjct: 118 PKPSEE 123



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 39/144 (27%), Positives = 53/144 (36%), Gaps = 32/144 (22%)

Query: 598 GGGSPSPS-TPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESP-----PPASPDGVT 651
           G G  SP   PE    S +R++   + S  +  E       SPESP     P       +
Sbjct: 75  GAGLESPQGQPEPGAASPQRQQDLHLESPQRQPEY------SPESPRCQPKPSEEAPKCS 128

Query: 652 EIRGLLA-------QGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSP--------PAS 696
           + +G+LA       + L P +P    P + G+P     Q    PE S P        P S
Sbjct: 129 QDQGVLASELAQNKEELTPGAPQHQLPPVPGSPEPYPGQQAPGPEPSQPLLELTPRAPGS 188

Query: 697 PLQHLLPGKAVDLGPPKPSDQETG 720
           P     P K     PP   +  TG
Sbjct: 189 PRGQHEPSK-----PPPAGETVTG 207


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 40/143 (27%), Positives = 56/143 (39%), Gaps = 9/143 (6%)

Query: 602 PSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPES-PPPASPDGVTEIRGLLAQG 660
           P+P  P +     ++ +        Q   +  P    P +  PP  P G T+     AQ 
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP---AQP 365

Query: 661 LRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGK--AVDLGPPKPSDQE 718
           L P + PPA    +  P+ E P PKA  +      +P Q   P K     +G PKP  Q+
Sbjct: 366 LGP-AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424

Query: 719 TGEQVSSPSSHPALHTTTEDSAG 741
            G Q  SP+  P    T     G
Sbjct: 425 PGLQ--SPAKAPGPTKTPVQQPG 445



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 27/144 (18%)

Query: 597 GGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGL 656
           GG  +P PS+P+      K + A    +    +    P + SP+       D        
Sbjct: 647 GGDLAPVPSSPQP-----KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD-------- 693

Query: 657 LAQGLRPESPPPA--GPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKP 714
           L++   P+ PPP    P L+G+P+ ++ QP  A ++ S PA P +           P  P
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA-DSLSKPAPPKE-----------PSVP 741

Query: 715 SDQETGEQVSSPSSHPALHTTTED 738
           S+Q+           P +   T D
Sbjct: 742 SEQDKAPVADDKPKQPKMVKPTTD 765



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 14/103 (13%)

Query: 638 SPESPPP---ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPP 694
           S E P P   A P GV +     AQ   P + PP   +    P  + P  ++  +A  P 
Sbjct: 382 SSEQPGPKALAQPPGVGKTP---AQQPGP-AKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437

Query: 695 ASPLQHLLPGK--AVDLGPPKPSDQETG-----EQVSSPSSHP 730
            +P+Q   PGK  A   GP K S Q+TG      Q+  P+  P
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 17/127 (13%)

Query: 627 QDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESP--QP 684
           Q +   LP +     P     D V   RG   + ++P  P P+ P +     G+ P  QP
Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIV---RG---ESVKPSLPSPSKPPIQQPTPGKPPAQQP 319

Query: 685 ---KAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETG-----EQVSSPSSHPALHTTT 736
              K+ P  + PPA P   L    A   G  KP  Q  G      Q   P+  PA  T +
Sbjct: 320 GHEKSQPGPAKPPAQP-SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS 378

Query: 737 EDSAGVQ 743
           E  +  Q
Sbjct: 379 EKPSSEQ 385



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 23/80 (28%), Positives = 27/80 (33%), Gaps = 7/80 (8%)

Query: 633  LPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASS 692
            LP  +   S  PA P        L      P  PPP        P    P P   P    
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP-------PPPPPPPPPPPPPPLP 2428

Query: 693  PPASPLQHLLPGKAVDLGPP 712
            PP SP   +LP K + +  P
Sbjct: 2429 PPTSPKPTILPKKKLTVASP 2448



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 21/71 (29%), Positives = 24/71 (33%), Gaps = 15/71 (21%)

Query: 633  LPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASS 692
            L   A P  PPP  P               P  PPP  P     P   SP+P   P+   
Sbjct: 2399 LDISAQPPPPPPPPP---------------PPPPPPPPPPPPPLPPPTSPKPTILPKKKL 2443

Query: 693  PPASPLQHLLP 703
              ASP+    P
Sbjct: 2444 TVASPVTTATP 2454


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 40/143 (27%), Positives = 56/143 (39%), Gaps = 9/143 (6%)

Query: 602 PSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPES-PPPASPDGVTEIRGLLAQG 660
           P+P  P +     ++ +        Q   +  P    P +  PP  P G T+     AQ 
Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP---AQP 365

Query: 661 LRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGK--AVDLGPPKPSDQE 718
           L P + PPA    +  P+ E P PKA  +      +P Q   P K     +G PKP  Q+
Sbjct: 366 LGP-AKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQ 424

Query: 719 TGEQVSSPSSHPALHTTTEDSAG 741
            G Q  SP+  P    T     G
Sbjct: 425 PGLQ--SPAKAPGPTKTPVQQPG 445



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 27/144 (18%)

Query: 597 GGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGL 656
           GG  +P PS+P+      K + A    +    +    P + SP+       D        
Sbjct: 647 GGDLAPVPSSPQP-----KLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQD-------- 693

Query: 657 LAQGLRPESPPPA--GPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKP 714
           L++   P+ PPP    P L+G+P+ ++ QP  A ++ S PA P +           P  P
Sbjct: 694 LSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEA-DSLSKPAPPKE-----------PSVP 741

Query: 715 SDQETGEQVSSPSSHPALHTTTED 738
           S+Q+           P +   T D
Sbjct: 742 SEQDKAPVADDKPKQPKMVKPTTD 765



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 33/103 (32%), Positives = 45/103 (43%), Gaps = 14/103 (13%)

Query: 638 SPESPPP---ASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPP 694
           S E P P   A P GV +     AQ   P + PP   +    P  + P  ++  +A  P 
Sbjct: 382 SSEQPGPKALAQPPGVGKTP---AQQPGP-AKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437

Query: 695 ASPLQHLLPGK--AVDLGPPKPSDQETG-----EQVSSPSSHP 730
            +P+Q   PGK  A   GP K S Q+TG      Q+  P+  P
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 17/127 (13%)

Query: 627 QDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESP--QP 684
           Q +   LP +     P     D V   RG   + ++P  P P+ P +     G+ P  QP
Sbjct: 266 QTDHAKLPLQRDASRPQTKQADIV---RG---ESVKPSLPSPSKPPIQQPTPGKPPAQQP 319

Query: 685 ---KAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETG-----EQVSSPSSHPALHTTT 736
              K+ P  + PPA P   L    A   G  KP  Q  G      Q   P+  PA  T +
Sbjct: 320 GHEKSQPGPAKPPAQP-SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS 378

Query: 737 EDSAGVQ 743
           E  +  Q
Sbjct: 379 EKPSSEQ 385



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 23/80 (28%), Positives = 27/80 (33%), Gaps = 7/80 (8%)

Query: 633  LPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASS 692
            LP  +   S  PA P        L      P  PPP        P    P P   P    
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP-------PPPPPPPPPPPPPPLP 2428

Query: 693  PPASPLQHLLPGKAVDLGPP 712
            PP SP   +LP K + +  P
Sbjct: 2429 PPTSPKPTILPKKKLTVASP 2448



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 21/71 (29%), Positives = 24/71 (33%), Gaps = 15/71 (21%)

Query: 633  LPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASS 692
            L   A P  PPP  P               P  PPP  P     P   SP+P   P+   
Sbjct: 2399 LDISAQPPPPPPPPP---------------PPPPPPPPPPPPPLPPPTSPKPTILPKKKL 2443

Query: 693  PPASPLQHLLP 703
              ASP+    P
Sbjct: 2444 TVASPVTTATP 2454


>gi|33356148 formin-like 1 [Homo sapiens]
          Length = 1100

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 42/145 (28%), Positives = 53/145 (36%), Gaps = 21/145 (14%)

Query: 591 EEYSNSGG-GGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGL-----------PFEAS 638
           E +S S   G S  P  PE A  +   R +   + V + EE GL             E  
Sbjct: 445 ERFSESTAMGASRRPPEPEKAPPAAPTRPSALELKVEELEEKGLIRILRGPGDAVSIEIL 504

Query: 639 P---------ESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPE 689
           P         ++P P  P G        A    P + PP  P L G P+ +   P A P+
Sbjct: 505 PVAVATPSGGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQ 564

Query: 690 ASSPPASPLQHLLPGKAVDLGPPKP 714
           A   P SP     P    DL PP P
Sbjct: 565 APPLPGSPEPPPAPPLPGDLPPPPP 589



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/122 (26%), Positives = 44/122 (36%), Gaps = 14/122 (11%)

Query: 598 GGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGL- 656
           GG +P+P  P  +   +    A+            LP   SP+  PP++P     + G  
Sbjct: 513 GGDAPTPGVPTGSPSPDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSP 572

Query: 657 -------LAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDL 709
                  L   L P  PPP  P     P  + P P   P    PP  P    L  +  +L
Sbjct: 573 EPPPAPPLPGDLPPPPPPPPPP-----PGTDGPVPPPPPPPPPPPGGP-PDALGRRDSEL 626

Query: 710 GP 711
           GP
Sbjct: 627 GP 628


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 30/92 (32%), Positives = 36/92 (39%), Gaps = 15/92 (16%)

Query: 640  ESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQ 699
            E PPP  P   T          +P+ PPP  P     PA  SP P  AP  SSPP  PL 
Sbjct: 1455 EKPPPTPPPAPTP---------QPQPPPPPPP---PQPALPSPPPLVAPTPSSPPPPPLP 1502

Query: 700  HLLPGKAVDLGPPKPSDQETGEQVSSPSSHPA 731
               P     +  P P        +++P   PA
Sbjct: 1503 ---PPPPPAMPSPPPPPPPAAAPLAAPPEEPA 1531



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 36/156 (23%), Positives = 56/156 (35%), Gaps = 14/156 (8%)

Query: 595  NSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIR 654
            ++GG  +P P  P      E   +        Q  E  +P   +PE P    P    + +
Sbjct: 1685 SAGGSSAPPPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKPSLLRPVEKEKEK 1744

Query: 655  GLLAQGLRPESPPPAGPLLNG--APAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPP 712
              + +G RP         L G  A +G   +P+ +     P  S L    P K     PP
Sbjct: 1745 EKVTRGERP---------LRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPP 1795

Query: 713  KPSD---QETGEQVSSPSSHPALHTTTEDSAGVQTE 745
            K      +E G   ++    P   + +E S G  +E
Sbjct: 1796 KKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSE 1831



 Score = 33.9 bits (76), Expect = 0.57
 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 12/90 (13%)

Query: 629 EEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESP---PPAGPLLNGAPAGESPQPK 685
           +E+G   + SP  PPP +        GLL +   P+ P   PP  P L  +    +P P 
Sbjct: 754 KELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSP- 812

Query: 686 AAPEASSPPASPL-QHLLPGKAVDLGPPKP 714
                 SP AS +  HLL     D G P+P
Sbjct: 813 ------SPSASKVGVHLLEPATRD-GAPQP 835



 Score = 33.1 bits (74), Expect = 0.96
 Identities = 44/165 (26%), Positives = 60/165 (36%), Gaps = 27/165 (16%)

Query: 590  GEEYSNSGG---GGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVG-----LPFEASPES 641
            GE    S G    G+   S   S T  +   + K+V     + + G     L F  S + 
Sbjct: 1235 GEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVEEKQPEMKSGFMASFLDFLKSGKR 1294

Query: 642  PPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPA-GESPQPKAAPEASSPPASPLQH 700
             PP    G+T           P SPP + P     PA G  PQP A P    PP S    
Sbjct: 1295 HPPLYQAGLTP----------PLSPPKSVP--PSVPARGLQPQPPATPAVPHPPPSGAFG 1342

Query: 701  L------LPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDS 739
            L         + + LG P P  +   E   +  + P+  +  EDS
Sbjct: 1343 LGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDS 1387



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 37/140 (26%), Positives = 46/140 (32%), Gaps = 26/140 (18%)

Query: 603  SPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLR 662
            S  TPE   L EK           Q +         P  PPP     +     L+A    
Sbjct: 1444 SNGTPEPPLLEEKPPPTPPPAPTPQPQ---------PPPPPPPPQPALPSPPPLVAP--T 1492

Query: 663  PESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQ 722
            P SPPP        P    P P A P  S PP  P     P  A    PP+     + E 
Sbjct: 1493 PSSPPP--------PPLPPPPPPAMP--SPPPPPP-----PAAAPLAAPPEEPAAPSPED 1537

Query: 723  VSSPSSHPALHTTTEDSAGV 742
               P + P      +++A V
Sbjct: 1538 PELPDTRPLHLAKKQETAAV 1557



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 24/82 (29%), Positives = 31/82 (37%), Gaps = 18/82 (21%)

Query: 639 PESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPL 698
           P  PPP  P  +     L + GL P                 +P P+  PE S  P   +
Sbjct: 837 PPPPPPPPPMPLQLEAHLRSHGLEP----------------AAPSPRLRPEESLDPPGAM 880

Query: 699 QHLLPGKAVDLGPPKPSDQETG 720
           Q LL   A++  PP P D   G
Sbjct: 881 QELL--GALEPLPPAPGDTGVG 900



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 32/133 (24%), Positives = 51/133 (38%), Gaps = 17/133 (12%)

Query: 602  PSPSTPESATLSEKRRRAKQV---VSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLA 658
            PS S+ E  ++++ R   + +   +S + D  +  P + S    PP +P           
Sbjct: 1378 PSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVP------ 1431

Query: 659  QGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQE 718
                   PPP  P L  A +  +P+P    E   P   P     P       PP+P+   
Sbjct: 1432 ------GPPPL-PGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPS 1484

Query: 719  TGEQVS-SPSSHP 730
                V+ +PSS P
Sbjct: 1485 PPPLVAPTPSSPP 1497


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 45/158 (28%), Positives = 62/158 (39%), Gaps = 10/158 (6%)

Query: 554  KEAAVQRKHNLYRDSMVMHNSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLS 613
            +E+    K +LY DS   ++S  +    +  +        S+S    S S S+ E     
Sbjct: 1009 EESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDE--E 1066

Query: 614  EKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDG--VTEIRGLLAQGLRPESP----P 667
            E+ R A    +     EV +P  A  E P P    G  VT +    A   RP  P    P
Sbjct: 1067 EEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESP 1126

Query: 668  PAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGK 705
            P+ PL    P    P P  AP     P+SP+  L P K
Sbjct: 1127 PSAPLRPPEPPAGPPAP--APRPDERPSSPIPLLPPPK 1162



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 38/155 (24%), Positives = 60/155 (38%), Gaps = 15/155 (9%)

Query: 573  NSDPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVG 632
            +S  +L+  ++G      +  S+S    S S S+  S++ S     +       ++    
Sbjct: 1014 SSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAA 1073

Query: 633  LPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGE-SPQPKAAPEAS 691
            LP  + P    P       E+         P     AG  +   P  E SP   A P   
Sbjct: 1074 LPSASPPPREVPVPTPAPVEV---------PVPERVAGSPVTPLPEQEASPARPAGPTEE 1124

Query: 692  SPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSP 726
            SPP++PL+   P      GPP P+ +   E+ SSP
Sbjct: 1125 SPPSAPLRPPEP----PAGPPAPAPR-PDERPSSP 1154



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 10/80 (12%)

Query: 627 QDEEVGLPF-----EASPES-----PPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGA 676
           ++E  G PF     E  P S     PP  S     + R   ++   PE P P G    G 
Sbjct: 389 REEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPASEAPPPEPPEPGGGGGGGG 448

Query: 677 PAGESPQPKAAPEASSPPAS 696
           P+ E  + + +P  +SP  S
Sbjct: 449 PSPEREEVRTSPRPASPARS 468


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 17/143 (11%)

Query: 604 PSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESP----------PPASPDGVTEI 653
           PS P S  LS     + Q  + +    +  PF   P  P          PP SP      
Sbjct: 634 PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 693

Query: 654 R---GLLAQGLRPESPPPAGPLL--NGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVD 708
           +    L A  L+    PPA P +  +  P  ++P P AAP    PP+ P    +   A  
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATP 753

Query: 709 LGPPKPSDQETGEQVSSPSSHPA 731
             PP+         +  P S PA
Sbjct: 754 --PPRVPPLLAAPPLQVPPSPPA 774



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 27/97 (27%), Positives = 37/97 (38%), Gaps = 18/97 (18%)

Query: 634 PFEASPE---SPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEA 690
           P +A P    +PPP +P  +               PP A P L   P    P P  +P A
Sbjct: 568 PLQAPPSPLTTPPPETPSSIAT------------PPPQAPPALASPPLQGLPSPPLSPLA 615

Query: 691 SSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPS 727
           + PP +P    LP       PP P        +++PS
Sbjct: 616 TPPPQAPPXLALPPLQ---APPSPPASPPLSPLATPS 649



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 30/117 (25%), Positives = 43/117 (36%), Gaps = 22/117 (18%)

Query: 638 SPESPPPASPDGVTEIRGLLAQGLRP--------------ESPPPAGPLLNGAPAGESPQ 683
           SP  PPP +P  +  +    A G +P              ES P AGP  +   +  +P 
Sbjct: 32  SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNP- 90

Query: 684 PKAAPEASSPPASPL-QHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDS 739
                 AS PPAS   +   P K    GP     + +G     P     L  + E++
Sbjct: 91  ------ASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEET 141



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 29/107 (27%), Positives = 39/107 (36%), Gaps = 8/107 (7%)

Query: 634 PFEASPESP--PPASPDGVTEIRGLLAQGLR----PESPPPAGPLLN--GAPAGESPQPK 685
           P +A P  P  PP SP      +   A  +     P SPPP+ P+      PA     P 
Sbjct: 629 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 688

Query: 686 AAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPAL 732
           A P + +PP+     L    +    PP         Q   P + P L
Sbjct: 689 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735



 Score = 33.5 bits (75), Expect = 0.74
 Identities = 38/150 (25%), Positives = 55/150 (36%), Gaps = 25/150 (16%)

Query: 604 PSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRP 663
           PS P S  +S   +   Q    +       P +A P   PPAS  G        +  + P
Sbjct: 770 PSPPASLPMSPLAKPPPQAPPALATP----PLQALPS--PPASFPGQAPFSPSASLPMSP 823

Query: 664 ESPPP--AGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGK-----------AVDLG 710
            + PP  A P+L        P P A+P   +P   P     PG            A+  G
Sbjct: 824 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP----TPGPDTSVSGPRLTLALAPG 879

Query: 711 PPKPSDQETGEQVSSP--SSHPALHTTTED 738
           PP P  +     +S P  + H +  T+T +
Sbjct: 880 PPPPPSRSPSSTLSGPDLAGHSSSATSTPE 909



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 34/127 (26%), Positives = 43/127 (33%), Gaps = 19/127 (14%)

Query: 604 PSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRP 663
           PS P S  +S       Q    +    + +P   SP + PP SP                
Sbjct: 708 PSPPASPPMSPSATPPPQAPPPLAAPPLQVP--PSPPASPPMSPSA-------------- 751

Query: 664 ESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVD--LGPPKPSDQETGE 721
            +PPP  P L  AP  + P    A    SP A P     P  A       P P     G+
Sbjct: 752 -TPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810

Query: 722 QVSSPSS 728
              SPS+
Sbjct: 811 APFSPSA 817



 Score = 31.2 bits (69), Expect = 3.7
 Identities = 36/148 (24%), Positives = 49/148 (33%), Gaps = 41/148 (27%)

Query: 616 RRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAG----- 670
           RRR      + +     L   A+P S P  S       RG       P  P P G     
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA---RGTPRAPAHPSQPKPKGLQALR 281

Query: 671 ---------------------PLLNGAPAGESPQPKAAPE-------ASSPPASPLQHLL 702
                                PL   +P+G   +P   P+       A+ PP+ PL   L
Sbjct: 282 PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL 341

Query: 703 PGKAVDLGPPKPSDQETGEQVSSPSSHP 730
           P     L PP PS   + + + SP + P
Sbjct: 342 P-----LAPPSPSAPPSLQTLPSPPATP 364


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 35/135 (25%), Positives = 54/135 (40%), Gaps = 9/135 (6%)

Query: 604  PSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRP 663
            P+ P+ AT+ +  ++  +      D  V      SP  PPP     V ++       L+P
Sbjct: 1226 PAYPKVATVPQSEKKPSKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKV----LSSLKP 1281

Query: 664  ESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQV 723
             +P PA      A A  +    A+  ++S  ASPL+H+L       G  K  D    E  
Sbjct: 1282 AAPSPATAATTAAAASTAASSTAS--SASKTASPLEHIL---QTLFGKKKSFDPSAREPP 1336

Query: 724  SSPSSHPALHTTTED 738
             S +  P    TT +
Sbjct: 1337 GSTAGLPQEPKTTAE 1351


>gi|62000702 diacylglycerol kinase kappa [Homo sapiens]
          Length = 1271

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 29/100 (29%), Positives = 39/100 (39%), Gaps = 14/100 (14%)

Query: 638 SPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASP 697
           SPE PPP  P               P +PPPA PLL  + A   P P+  PE +  P   
Sbjct: 23  SPEPPPPWPPPPP------------PPAPPPAPPLL--SEASPEPIPEPCPELAPGPCPE 68

Query: 698 LQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTE 737
                  +      P+P+ +   E    P++ PA    TE
Sbjct: 69  ATSESATELYTEPTPEPATEPASEPAPEPATEPAPEPATE 108



 Score = 38.5 bits (88), Expect = 0.023
 Identities = 34/122 (27%), Positives = 47/122 (38%), Gaps = 14/122 (11%)

Query: 636 EASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGES-----------PQP 684
           E  P  PPP  P        LL++   PE  P   P L   P  E+           P P
Sbjct: 25  EPPPPWPPPPPPPAPPPAPPLLSEA-SPEPIPEPCPELAPGPCPEATSESATELYTEPTP 83

Query: 685 KAAPEASSPPA-SPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDSAGVQ 743
           + A E +S PA  P     P  A +   P+P+ +   E    P+  PAL +  E +  + 
Sbjct: 84  EPATEPASEPAPEPATEPAPEPATE-PAPEPAPEPATESAPEPTPEPALESVPEPAPELT 142

Query: 744 TE 745
            E
Sbjct: 143 PE 144



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 33/126 (26%), Positives = 46/126 (36%), Gaps = 8/126 (6%)

Query: 575 DPNLHLLAEGAPIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLP 634
           +P     +E AP    E         +P P+ PE AT S      +  +  V +    L 
Sbjct: 84  EPATEPASEPAPEPATEPAPEPATEPAPEPA-PEPATESAPEPTPEPALESVPEPAPELT 142

Query: 635 FEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAG-------ESPQPKAA 687
            E +PE  P  +P+ VTE+         PE  P   P L   P          SP P  +
Sbjct: 143 PEVAPELAPEPTPEPVTELAPEFCPEAAPEFRPSPAPCLLQCPVDTRERGLKTSPSPSPS 202

Query: 688 PEASSP 693
           P   +P
Sbjct: 203 PSPRTP 208



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 23/89 (25%), Positives = 35/89 (39%), Gaps = 8/89 (8%)

Query: 665 SPPPAGPLLNGAPAGESPQPKAAPEASSPPASPL-----QHLLPGKAVDLGP---PKPSD 716
           +PP  G     +P    P P   P  + PPA PL        +P    +L P   P+ + 
Sbjct: 12  APPQDGEQPAESPEPPPPWPPPPPPPAPPPAPPLLSEASPEPIPEPCPELAPGPCPEATS 71

Query: 717 QETGEQVSSPSSHPALHTTTEDSAGVQTE 745
           +   E  + P+  PA    +E +    TE
Sbjct: 72  ESATELYTEPTPEPATEPASEPAPEPATE 100


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 38/144 (26%), Positives = 45/144 (31%), Gaps = 42/144 (29%)

Query: 597 GGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGL 656
           G G  P+P+ P + T                         A P +PPP  P         
Sbjct: 144 GSGPGPTPTPPPAVT------------------------SAPPGAPPPTPPSSGV----- 174

Query: 657 LAQGLRPESPPPAG--PLLNGAPAGESPQPKAAPEASSP-----PASPLQHLLPGKAVDL 709
                 P +PP AG  P    A  G  P PK  P    P     P  P     PG +   
Sbjct: 175 ------PTTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPG 228

Query: 710 GPPKPSDQETGEQVSSPSSHPALH 733
           G PKP  +  GE       HP  H
Sbjct: 229 GHPKPPHRGGGEPRGGRQHHPPYH 252



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 36/133 (27%), Positives = 47/133 (35%), Gaps = 21/133 (15%)

Query: 598 GGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASP---ESPPPASPDGVTEIR 654
           G   P P  P      ++++   Q     Q      P    P   + PPP   D    + 
Sbjct: 52  GQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPV- 110

Query: 655 GLLAQGLRP-----------ESPPPAGPLLNGAPAGESPQPKAAPE---ASSPPASPLQH 700
             +AQG  P            S PPA P  +GAP G  P P   P     S+PP +P   
Sbjct: 111 --VAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP-PP 167

Query: 701 LLPGKAVDLGPPK 713
             P   V   PP+
Sbjct: 168 TPPSSGVPTTPPQ 180


>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
          Length = 464

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 32/96 (33%), Positives = 37/96 (38%), Gaps = 6/96 (6%)

Query: 639 PESPP--PASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPAS 696
           P +PP  PA P GV      L  GL P  P P    L   P G  P P   P   +P   
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGLPPRPPLPES--LPPPPPGGLPLPPMPPTGPAPSGP 274

Query: 697 PLQHLLPGKAVDLGPPKP--SDQETGEQVSSPSSHP 730
           P    LP  A  + PP P      +G    +P  HP
Sbjct: 275 PGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHP 310



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 9/96 (9%)

Query: 639 PESPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASS--PPAS 696
           PES PP  P G+  +  +   G  P  PP    L   AP    P P   P AS   PPA 
Sbjct: 248 PESLPPPPPGGLP-LPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAP 306

Query: 697 PLQHLLPGKAVDLGPPKPS--DQETGEQVSSPSSHP 730
            +    PG    + PP P      +G    +P  HP
Sbjct: 307 GVHPPAPG----VHPPAPGVHPPTSGVHPPAPGVHP 338



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 24/79 (30%), Positives = 32/79 (40%), Gaps = 6/79 (7%)

Query: 658 AQGLRPESP---PPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKP 714
           A G+ P +P   PPA  +   AP G  P P A     +P   P    +  +A  + PP P
Sbjct: 340 APGVHPPAPGVHPPAPGVHPPAP-GVHPPPSAGVHPQAPGVHPAAPAVHPQAPGVHPPAP 398

Query: 715 S--DQETGEQVSSPSSHPA 731
               Q  G     P  HP+
Sbjct: 399 GMHPQAPGVHPQPPGVHPS 417


>gi|38787970 tensin like C1 domain containing phosphatase isoform 3
            [Homo sapiens]
          Length = 1285

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 43/155 (27%), Positives = 55/155 (35%), Gaps = 21/155 (13%)

Query: 585  APIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFE-------- 636
            +P DW +E S  G     SP +P   TL   R    Q      D   G P          
Sbjct: 858  SPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPW 917

Query: 637  --ASPE----SPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEA 690
              ASPE    SP PA P   +     L+Q   PE     GP       G+ P P    +A
Sbjct: 918  LVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGP-------GQQPGPWGPEQA 970

Query: 691  SSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSS 725
            SSP      H+     +    P+  +  T E  S+
Sbjct: 971  SSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSN 1005


>gi|38787957 tensin like C1 domain containing phosphatase isoform 2
            [Homo sapiens]
          Length = 1409

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 43/155 (27%), Positives = 55/155 (35%), Gaps = 21/155 (13%)

Query: 585  APIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFE-------- 636
            +P DW +E S  G     SP +P   TL   R    Q      D   G P          
Sbjct: 982  SPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPW 1041

Query: 637  --ASPE----SPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEA 690
              ASPE    SP PA P   +     L+Q   PE     GP       G+ P P    +A
Sbjct: 1042 LVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGP-------GQQPGPWGPEQA 1094

Query: 691  SSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSS 725
            SSP      H+     +    P+  +  T E  S+
Sbjct: 1095 SSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSN 1129


>gi|38787941 tensin like C1 domain containing phosphatase isoform 1
            [Homo sapiens]
          Length = 1419

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 43/155 (27%), Positives = 55/155 (35%), Gaps = 21/155 (13%)

Query: 585  APIDWGEEYSNSGGGGSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFE-------- 636
            +P DW +E S  G     SP +P   TL   R    Q      D   G P          
Sbjct: 992  SPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPW 1051

Query: 637  --ASPE----SPPPASPDGVTEIRGLLAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEA 690
              ASPE    SP PA P   +     L+Q   PE     GP       G+ P P    +A
Sbjct: 1052 LVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGP-------GQQPGPWGPEQA 1104

Query: 691  SSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSS 725
            SSP      H+     +    P+  +  T E  S+
Sbjct: 1105 SSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSN 1139


>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
           sapiens]
          Length = 247

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 12/94 (12%)

Query: 642 PPPASPDGVTEIRGLLAQGL-----RPESPPPAGPLLNGAPAGESPQPKAAPEASSPPAS 696
           PPP  P+G     G  +QG      +PE PPP G    G  +  +P P   PE   P   
Sbjct: 73  PPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQG----GNQSQGTPPPPGKPERPPPQGG 128

Query: 697 PLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHP 730
              H  P      G P+    + G Q   P  HP
Sbjct: 129 NQSHRPPPPP---GKPERPPPQGGNQSQGPPPHP 159



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 8/72 (11%)

Query: 634 PFEASPESPPPASPDGVTEIRGLLA--------QGLRPESPPPAGPLLNGAPAGESPQPK 685
           P    PE PPP   +     R            +G +P+ PPP G      PAG +PQ  
Sbjct: 157 PHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQP 216

Query: 686 AAPEASSPPASP 697
            AP A  P   P
Sbjct: 217 QAPPAGKPQGPP 228



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 32/104 (30%), Positives = 39/104 (37%), Gaps = 21/104 (20%)

Query: 634 PFEASPESPPPASPDGVTEIRGLLAQGLRPESPPPAG-------PLLNGAPAGESPQPKA 686
           P    PE PPP    G  + +G      +PE PPP G       P   G P  E P P+ 
Sbjct: 94  PHPGKPERPPP---QGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKP--ERPPPQG 148

Query: 687 APEASSPPASPLQHLLPGKAVDLGPPKPSDQETGEQVSSPSSHP 730
             ++  PP        PGK    GPP P +        SP   P
Sbjct: 149 GNQSQGPPPH------PGKPE--GPP-PQEGNKSRSARSPPGKP 183



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 23/81 (28%), Positives = 30/81 (37%), Gaps = 7/81 (8%)

Query: 672 LLNGAPAGESPQPKAAPEASSPPASPLQHLLP-GKAVDLGPPKPSDQ------ETGEQVS 724
           L++G P G  PQ    P+   PP    Q   P G     GPP P  +      + G Q  
Sbjct: 31  LISGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQ 90

Query: 725 SPSSHPALHTTTEDSAGVQTE 745
            P  HP          G Q++
Sbjct: 91  GPPPHPGKPERPPPQGGNQSQ 111


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 21/165 (12%)

Query: 594  SNSGGGGSPSP----STPESATLSEKRRRAKQVVSVVQDEEVGLPF--EASPESPPPA-- 645
            S  GG  +PSP    +TP +   S K   A              P   +  P +PPP   
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263

Query: 646  -SPDGVT--EIRGLLAQGLRPESPPPA---GPLLNGAPAGESPQPKAAPEASSPPASPLQ 699
             +P   T   ++G LA      +P PA    P   G PA   P+    P A++PP+    
Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS---- 1319

Query: 700  HLLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDSAGVQT 744
               P  +    PPK +         SP   P L  TT  S G  T
Sbjct: 1320 ---PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361



 Score = 36.6 bits (83), Expect = 0.087
 Identities = 42/162 (25%), Positives = 52/162 (32%), Gaps = 35/162 (21%)

Query: 594  SNSGGGGSPSPS---TPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGV 650
            S  GG  +PSP    TP + T    +                 PF     +PP A+P   
Sbjct: 995  SPKGGPATPSPKGAPTPPAVTPPSPK-----------GSPAATPFPKGASTPPAATPPSP 1043

Query: 651  TEIRGLLAQGLRPESPP-------------PAGPLLNGAP---AGESPQPKAAPEASSPP 694
               +G  A    P+  P             PA P L GAP   A   P PK  P   SP 
Sbjct: 1044 ---KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPK 1100

Query: 695  ASPLQHLL--PGKAVDLGPPKPSDQETGEQVSSPSSHPALHT 734
             +P+      P     L  P      T    + PS    L T
Sbjct: 1101 GAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLAT 1142



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 35/141 (24%), Positives = 48/141 (34%), Gaps = 20/141 (14%)

Query: 603  SPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPP------PASPDGVTEIRGL 656
            +P +P+    +   + A    +       G P    P+  P      P SP G   +   
Sbjct: 1293 TPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPAT 1352

Query: 657  LAQG----LRPES-----PPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAV 707
                      P S     PP A P   G PA   P PK  P   SP   P    +    +
Sbjct: 1353 TPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV----I 1408

Query: 708  DLGPPK-PSDQETGEQVSSPS 727
             L P K P+   T E  ++PS
Sbjct: 1409 PLSPKKAPATPVTREGAATPS 1429



 Score = 35.0 bits (79), Expect = 0.25
 Identities = 34/134 (25%), Positives = 51/134 (38%), Gaps = 8/134 (5%)

Query: 600  GSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPE---SPPPASPDGVTEIRGL 656
            G  +P+  ++  LS      K+  +    +  G+P   SP+   +PP A+P         
Sbjct: 899  GPATPAPKQAPALSMTSSSPKKARATPAPK--GIPASPSPKGAPTPPAATPPSPKGGPAT 956

Query: 657  LAQGLRPESPPPAGPLLNGAPAGESPQPKAAPEASSPPASPLQHLLPGKAVDLGPPKPSD 716
             +    P  P    P   G PA  SP+    P A++PP SP     P      G P P  
Sbjct: 957  PSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP-SPKGG--PATPSPKGAPTPPA 1013

Query: 717  QETGEQVSSPSSHP 730
                    SP++ P
Sbjct: 1014 VTPPSPKGSPAATP 1027



 Score = 34.7 bits (78), Expect = 0.33
 Identities = 45/158 (28%), Positives = 59/158 (37%), Gaps = 31/158 (19%)

Query: 594  SNSGGGGSPSP----STPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDG 649
            S  GG  +PSP    +TP +   S K         +      G P   +P + PP SP G
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKG-------GLATPSPKGAP--TTPAATPP-SPKG 1230

Query: 650  VTEIRGLLAQGLR--PESPPPAGPLLNGAPAGESPQPKAAPEASSPP------ASPLQHL 701
                 GL     +  P +P    P   G PA   P+    P A++PP      A+P    
Sbjct: 1231 -----GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG 1285

Query: 702  LPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDS 739
             P  AV + PP P   + G   S P   P     T  S
Sbjct: 1286 APNPAV-VTPPSP---KGGPATSPPKGAPTPPAATPPS 1319



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 26/100 (26%), Positives = 35/100 (35%), Gaps = 1/100 (1%)

Query: 642  PPPASPDGVTEIRGLLAQGLRPESPPPAG-PLLNGAPAGESPQPKAAPEASSPPASPLQH 700
            P P  P    ++    +    P +P P G P L         +  A P +   P +P   
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTAT 1532

Query: 701  LLPGKAVDLGPPKPSDQETGEQVSSPSSHPALHTTTEDSA 740
            LL  K      PK +       V SP   PA+ T  E  A
Sbjct: 1533 LLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPA 1572



 Score = 30.8 bits (68), Expect = 4.8
 Identities = 37/152 (24%), Positives = 48/152 (31%), Gaps = 14/152 (9%)

Query: 600  GSPSPSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQ 659
            G P+  +P+ A +            +      G P   +P + PP SP G          
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP--TTPAATPP-SPKGGLATPPPKGA 1148

Query: 660  GLRPESPPP------AGPLLNGAP---AGESPQPKAAPEASSPPASPLQHLL--PGKAVD 708
               P + PP      A P   GAP   A   P PK      SP  +P       P     
Sbjct: 1149 PTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208

Query: 709  LGPPKPSDQETGEQVSSPSSHPALHTTTEDSA 740
            L  P P    T    + PS    L T +   A
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGA 1240



 Score = 30.4 bits (67), Expect = 6.2
 Identities = 39/135 (28%), Positives = 46/135 (34%), Gaps = 30/135 (22%)

Query: 594  SNSGGGGSPSPS---TPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPP------P 644
            S  GG  +PSP    TP +AT    +               G P   SP+  P      P
Sbjct: 949  SPKGGPATPSPKWAPTPPAATPPSPK---------------GGPATPSPKGAPTPPAATP 993

Query: 645  ASPDGVTEIRGLLAQGLRPESPPPA---GPLLNGAPAGESPQPKAAPEA--SSPPASPLQ 699
             SP G             P   PP+    P     P G S  P A P +   SP A+PL 
Sbjct: 994  PSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053

Query: 700  HLLP-GKAVDLGPPK 713
               P   A  L  PK
Sbjct: 1054 KGAPTTPAATLPSPK 1068



 Score = 30.0 bits (66), Expect = 8.2
 Identities = 37/150 (24%), Positives = 55/150 (36%), Gaps = 30/150 (20%)

Query: 604  PSTPESATLSEKRRRAKQVVSVVQDEEVGLPFEASPESPPPASPDGVTEIRGLLAQGLRP 663
            P  P+    S   ++A    + +    +     +SP+  P A+P    +     A  L  
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVP-ATPSSRRDPIAPTATLLSK 1536

Query: 664  ESP----------PPAGPLLNGAPAGESPQPKAAP------EASSPPA----------SP 697
            ++P          PPA  + +       P PK AP      EASSPPA          SP
Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSP 1596

Query: 698  LQHLLPGKAVDLGPPKPSDQETGEQVSSPS 727
             + L+P        P P +  T   V+ PS
Sbjct: 1597 KELLIPPAVTS---PSPKEAPTPPAVTPPS 1623


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,407,796
Number of Sequences: 37866
Number of extensions: 1694893
Number of successful extensions: 13849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 841
Number of HSP's that attempted gapping in prelim test: 10194
Number of HSP's gapped (non-prelim): 3378
length of query: 746
length of database: 18,247,518
effective HSP length: 110
effective length of query: 636
effective length of database: 14,082,258
effective search space: 8956316088
effective search space used: 8956316088
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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