BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|50428935 BPY2 interacting protein 1 [Homo sapiens] (1059 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 2118 0.0 gi|153945728 microtubule-associated protein 1B [Homo sapiens] 446 e-125 gi|95147555 microtubule-associated protein 1A [Homo sapiens] 293 6e-79 gi|163965366 nascent polypeptide-associated complex alpha subuni... 92 3e-18 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 90 1e-17 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 90 1e-17 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 90 1e-17 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 90 1e-17 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 87 6e-17 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 83 1e-15 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 82 2e-15 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 76 1e-13 gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 70 1e-11 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 70 1e-11 gi|31324577 molecule interacting with Rab13 [Homo sapiens] 69 2e-11 gi|150170670 piccolo isoform 2 [Homo sapiens] 69 3e-11 gi|150378539 piccolo isoform 1 [Homo sapiens] 69 3e-11 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 68 5e-11 gi|148727255 microtubule associated serine/threonine kinase fami... 67 1e-10 gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 66 2e-10 gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 66 2e-10 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 66 2e-10 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 66 2e-10 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 66 2e-10 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 65 3e-10 gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 64 6e-10 gi|157074225 nuclear pore complex interacting protein-like 3 [Ho... 64 6e-10 gi|167736355 mucin 4 isoform a [Homo sapiens] 64 1e-09 gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 64 1e-09 gi|91982772 mucin 17 [Homo sapiens] 64 1e-09 >gi|50428935 BPY2 interacting protein 1 [Homo sapiens] Length = 1059 Score = 2118 bits (5489), Expect = 0.0 Identities = 1059/1059 (100%), Positives = 1059/1059 (100%) Query: 1 MAAVAGSGAAAAPSSLLLVVGSEFGSPGLLTYVLEELERGIRSWDVDPGVCNLDEQLKVF 60 MAAVAGSGAAAAPSSLLLVVGSEFGSPGLLTYVLEELERGIRSWDVDPGVCNLDEQLKVF Sbjct: 1 MAAVAGSGAAAAPSSLLLVVGSEFGSPGLLTYVLEELERGIRSWDVDPGVCNLDEQLKVF 60 Query: 61 VSRHSATFSSIVKGQRSLHHRGDNLETLVLLNPSDKSLYDELRNLLLDPASHKLLVLAGP 120 VSRHSATFSSIVKGQRSLHHRGDNLETLVLLNPSDKSLYDELRNLLLDPASHKLLVLAGP Sbjct: 61 VSRHSATFSSIVKGQRSLHHRGDNLETLVLLNPSDKSLYDELRNLLLDPASHKLLVLAGP 120 Query: 121 CLEETGELLLQTGGFSPHHFLQVLKDREIRDILATTPPPVQPPILTITCPTFGDWAQLAP 180 CLEETGELLLQTGGFSPHHFLQVLKDREIRDILATTPPPVQPPILTITCPTFGDWAQLAP Sbjct: 121 CLEETGELLLQTGGFSPHHFLQVLKDREIRDILATTPPPVQPPILTITCPTFGDWAQLAP 180 Query: 181 AVPGLQGALRLQLRLNPPAQLPNSEGLCEFLEYVAESLEPPSPFELLEPPTSGGFLRLGR 240 AVPGLQGALRLQLRLNPPAQLPNSEGLCEFLEYVAESLEPPSPFELLEPPTSGGFLRLGR Sbjct: 181 AVPGLQGALRLQLRLNPPAQLPNSEGLCEFLEYVAESLEPPSPFELLEPPTSGGFLRLGR 240 Query: 241 PCCYIFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHPGADSLPG 300 PCCYIFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHPGADSLPG Sbjct: 241 PCCYIFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHPGADSLPG 300 Query: 301 LNSLLRRKLAERSEVAAGGGSWDDRLRRLISPNLGVVFFNACEAASRLARGEDEAELALS 360 LNSLLRRKLAERSEVAAGGGSWDDRLRRLISPNLGVVFFNACEAASRLARGEDEAELALS Sbjct: 301 LNSLLRRKLAERSEVAAGGGSWDDRLRRLISPNLGVVFFNACEAASRLARGEDEAELALS 360 Query: 361 LLAQLGITPLPLSRGPVPAKPTVLFEKMGVGRLDMYVLHPPSAGAERTLASVCALLVWHP 420 LLAQLGITPLPLSRGPVPAKPTVLFEKMGVGRLDMYVLHPPSAGAERTLASVCALLVWHP Sbjct: 361 LLAQLGITPLPLSRGPVPAKPTVLFEKMGVGRLDMYVLHPPSAGAERTLASVCALLVWHP 420 Query: 421 AGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEGPGRAESKESVGSRD 480 AGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEGPGRAESKESVGSRD Sbjct: 421 AGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEGPGRAESKESVGSRD 480 Query: 481 SSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPRE 540 SSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPRE Sbjct: 481 SSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPRE 540 Query: 541 VRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGS 600 VRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGS Sbjct: 541 VRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGS 600 Query: 601 PASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLR 660 PASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLR Sbjct: 601 PASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLR 660 Query: 661 GGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLP 720 GGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLP Sbjct: 661 GGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLP 720 Query: 721 LRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAE 780 LRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAE Sbjct: 721 LRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAE 780 Query: 781 ETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSI 840 ETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSI Sbjct: 781 ETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSI 840 Query: 841 CMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLS 900 CMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLS Sbjct: 841 CMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLS 900 Query: 901 ARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSSA 960 ARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSSA Sbjct: 901 ARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSSA 960 Query: 961 HLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQHWDRDLQVTLIPTFDSVAM 1020 HLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQHWDRDLQVTLIPTFDSVAM Sbjct: 961 HLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQHWDRDLQVTLIPTFDSVAM 1020 Query: 1021 HTWYAETHARHQALGITVLGSNSMVSMQDDAFPACKVEF 1059 HTWYAETHARHQALGITVLGSNSMVSMQDDAFPACKVEF Sbjct: 1021 HTWYAETHARHQALGITVLGSNSMVSMQDDAFPACKVEF 1059 >gi|153945728 microtubule-associated protein 1B [Homo sapiens] Length = 2468 Score = 446 bits (1147), Expect = e-125 Identities = 270/639 (42%), Positives = 374/639 (58%), Gaps = 81/639 (12%) Query: 3 AVAGSGAAAAPSS---------LLLVVGSEFGSPGLLTYVLEELERGIRSWDVDPGVCNL 53 ++A A+ +PS LLVV E + L + +E GIRSWD + CNL Sbjct: 16 SIANPAASTSPSLSHRFLDSKFYLLVVVGEIVTEEHLRRAIGNIELGIRSWDTNLIECNL 75 Query: 54 DEQLKVFVSRHSATFSSIVKGQRSLHHRGDNLETLVLLNPSDKSLYDELRNLLLDPASHK 113 D++LK+FVSRHSA FS V GQ+ LHHR D LET+VL+NPSD+++ E+R ++ D A HK Sbjct: 76 DQELKLFVSRHSARFSPEVPGQKILHHRSDVLETVVLINPSDEAVSTEVRLMITDAARHK 135 Query: 114 LLVLAGPCLEETGELLLQTGGFSPHHFLQVLKDREIRDILATTPPPVQPPILTITCPTFG 173 LLVL G C E TGEL+LQ+G FS +F+++ D+EI ++L+TT P LT+ CP G Sbjct: 136 LLVLTGQCFENTGELILQSGSFSFQNFIEIFTDQEIGELLSTTHP-ANKASLTLFCPEEG 194 Query: 174 DWAQLAPAVPGLQGALRLQLRLNPPAQLPNSEGLCEFLEYVAESLEPPSPFELLEPPTSG 233 DW LQ + + +LN + LP EGL EF EY++ES+E PSPF++LEPPTSG Sbjct: 195 DWKNSNLDRHNLQDFINI--KLNSASILPEMEGLSEFTEYLSESVEVPSPFDILEPPTSG 252 Query: 234 GFLRLGRPCCYIFPGGLGDAAFFAVNGFTVLVNGGSNPKSSFWKLVRHLDRVDAVLVTHP 293 GFL+L +PCCYIFPGG GD+A FAVNGF +L+NGGS KS FWKL+RHLDRVD++L+TH Sbjct: 253 GFLKLSKPCCYIFPGGRGDSALFAVNGFNMLINGGSERKSCFWKLIRHLDRVDSILLTHI 312 Query: 294 GADSLPGLNSLLRRKLAERSEVAAGGGSWD-DRLRRLISPNLGVVFFNACEAAS------ 346 G D+LPG+NS+L+RK+AE E + G + + D ++ LISP+LGVVF N E Sbjct: 313 GDDNLPGINSMLQRKIAELEEEQSQGSTTNSDWMKNLISPDLGVVFLNVPENLKNPEPNI 372 Query: 347 RLARGEDEAELALSLLAQLGITPLPLSRG-PVPAKPTVLFEKMGVGRLDMYVLHPPSAGA 405 ++ R +EA L L +L + P PL R P +LF+KMGVG+L+MYVL+P + Sbjct: 373 KMKRSIEEACFTLQYLNKLSMKPEPLFRSVGNTIDPVILFQKMGVGKLEMYVLNPVKSSK 432 Query: 406 ERT------------------------------LASVCALLVWHPAGPGEKVVRVLFPGC 435 E L SV +L+VWHPA P EK++RVLFPG Sbjct: 433 EMQYFMQQWTGTNKDKAEFILPNGQEVDLPISYLTSVSSLIVWHPANPAEKIIRVLFPGN 492 Query: 436 TPPACLLDGLVRLQHLRFLREPVVTPQDLEG------------PGRAESKESV------- 476 + +L+GL +L+HL FL++P+ T +DL G RA+S+ES+ Sbjct: 493 STQYNILEGLEKLKHLDFLKQPLATQKDLTGQVPTPVVKQTKLKQRADSRESLKPAAKPL 552 Query: 477 ---GSRDSSKREGLLATHPRPGQERPGVARKEP--ARAEAPRKTE-KEAKTPREL--KKD 528 R SK E T ++ P V KE + + P KTE K + T +E+ K++ Sbjct: 553 PSKSVRKESKEETPEVTKVNHVEKPPKVESKEKVMVKKDKPIKTETKPSVTEKEVPSKEE 612 Query: 529 PKP---SVSRTQPREVRRAASSVPNLKKTNAQAAPKPRK 564 P P V+ Q +V+ A+ +KK + P+ +K Sbjct: 613 PSPVKAEVAEKQATDVKPKAAKEKTVKK-ETKVKPEDKK 650 Score = 207 bits (527), Expect = 4e-53 Identities = 160/477 (33%), Positives = 233/477 (48%), Gaps = 85/477 (17%) Query: 649 EGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPP 708 E +E+++ P G + ++ T TP +T + T ++ + S+E Sbjct: 2009 ETTEKITSFPESEGYSYETSTKTTRTPDTSTYCYET---AEKITRTPQASTYSYE----- 2060 Query: 709 SAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPG-----SS 763 TS+ + + P R DVDLCLVS CE++H K ++P+ +P +S Sbjct: 2061 ---TSDLCYTAEKKSPSEARQ----DVDLCLVSSCEYKHPKT-ELSPSFINPNPLEWFAS 2112 Query: 764 NDSSARSQE--------------RAGGLGAEETPPTSVSESLPTLSDSDPVP-------- 801 + + S++ + G +ETPPTSVSES P+ +DSD P Sbjct: 2113 EEPTEESEKPLTQSGGAPPPPGGKQQGRQCDETPPTSVSESAPSQTDSDVPPETEECPSI 2172 Query: 802 LAPGAADSDEDTEGFGVPRH------DPLPDPLKVPPPLPDPSSICMVDPEMLPPKT--- 852 A DS++++E + DP P P++ P P + MVDPE L + Sbjct: 2173 TADANIDSEDESETIPTDKTVTYKHMDPPPAPVQDRSPSPRHPDVSMVDPEALAIEQNLG 2232 Query: 853 ---ARQTENVSRTRKPLARPNSRAAAPKAT----PVAAA-KTKGLA-GGDRASRPLS--- 900 + + ++T+KP + S + K+ P+AA+ K GL D+ SR S Sbjct: 2233 KALKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKK 2292 Query: 901 ------------------ARSEPSEKGGR-APLSRKSSTPKTATRGPSGSASSRPGVSAT 941 AR E +K + A + S + KTAT GP + +++ SA Sbjct: 2293 KESVEKAAKPTTTPEVKAARGEEKDKETKNAANASASKSAKTATAGPGTTKTTKS--SAV 2350 Query: 942 PPKSPVYLDLAYLPSGSSAHLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQ 1001 PP PVYLDL Y+P+ S++ VD EFF+RVR+ YV+SG D EE RAVLDALL K Sbjct: 2351 PPGLPVYLDLCYIPNHSNSKNVDVEFFKRVRSSYYVVSGNDPAAEEPSRAVLDALLEGKA 2410 Query: 1002 HWDRDLQVTLIPTFDSVAMHTWYAETHARHQALGITVLGSNSMVSMQDDAFPACKVE 1058 W ++QVTLIPT DS M WY ETH + Q L I VL S+S V MQD++FPACK+E Sbjct: 2411 QWGSNMQVTLIPTHDSEVMREWYQETHEKQQDLNIMVLASSSTVVMQDESFPACKIE 2467 Score = 50.8 bits (120), Expect = 7e-06 Identities = 70/267 (26%), Positives = 100/267 (37%), Gaps = 36/267 (13%) Query: 670 PTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQV--------LPPSAPTSEAGLSL-- 719 P TT V+ PSL AEVGSPHSTEVD+SLSVS Q + PS +S+ Sbjct: 1563 PEPTTDDVS-PSLHAEVGSPHSTEVDDSLSVSVVQTPTTFQETEMSPSKEECPRPMSISP 1621 Query: 720 PLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGA 779 P P+ +S +P S E + P + S S AG L Sbjct: 1622 PDFSPKTAKSRTPVQDHRSEQSSMSIEFGQESP--EQSLAMDFSRQSPDHPTVGAGVLHI 1679 Query: 780 EETPPTSVSESLPTLSDSD-----PVPLAPGAADSDEDTEGFGVPRHDPLPD------PL 828 E PT V S + DS P P ++ +E V + + P P Sbjct: 1680 TENGPTEVDYSPSDMQDSSLSHKIPPMEEPSYTQDNDLSELISVSQVEASPSTSSAHTPS 1739 Query: 829 KVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNS-------RAAAPKATP- 880 ++ PL + + + P + + +E V P S R ++P +P Sbjct: 1740 QIASPLQEDTLSDVAPPRDMSLYASLTSEKVQSLEGEKLSPKSDISPLTPRESSPLYSPT 1799 Query: 881 ----VAAAKTKGLAGGDRASRPLSARS 903 +A K K +S P+ A S Sbjct: 1800 FSDSTSAVKEKTATCHSSSSPPIDAAS 1826 Score = 37.4 bits (85), Expect = 0.075 Identities = 40/154 (25%), Positives = 64/154 (41%), Gaps = 26/154 (16%) Query: 454 LREPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKE-------- 505 ++ V Q + +A +++V K E +P +E VA+KE Sbjct: 616 VKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKE---VAKKEDKTPIKKE 672 Query: 506 --PARAEAPRKTEKEAKTPRELKKDPKPSVSR-TQPREVRRAASSVPNLKKTNAQAAPKP 562 P + E ++ +KE K +E KK+PK V + T P+EV++ +KK + K Sbjct: 673 EKPKKEEVKKEVKKEIK--KEEKKEPKKEVKKETPPKEVKK------EVKKEEKKEVKKE 724 Query: 563 RKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSA 596 K P P A +P S EA P+A Sbjct: 725 EKEPKKEIKKLPKDAKKSSTPLS----EAKKPAA 754 Score = 32.7 bits (73), Expect = 1.9 Identities = 37/172 (21%), Positives = 71/172 (41%), Gaps = 11/172 (6%) Query: 473 KESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTP-RELKKDPKP 531 KE ++ K+E +E +KE E ++ +KE K ++ +K+PK Sbjct: 671 KEEKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKK 730 Query: 532 SVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRC--- 588 + + P++ +++++ + KK A P+K S A P+ ++ Sbjct: 731 EIKKL-PKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSV--AAGKPKEKGKIKVIKK 787 Query: 589 -GEASPP-SAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRT 638 G+A+ +AA G+ A+ + + I G K LE + S P T Sbjct: 788 EGKAAEAVAAAVGTGATTAAVMAAAGIAAI--GPAKELEAERSLMSSPEDLT 837 Score = 30.8 bits (68), Expect = 7.1 Identities = 48/221 (21%), Positives = 77/221 (34%), Gaps = 16/221 (7%) Query: 465 EGPGRAESKESVGS------RDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKE 518 E P + E K+ V + K+E T P+ ++ K+ + E ++ Sbjct: 673 EKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVKKEEKKEVKKEEKEPKKEI 732 Query: 519 AKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPR-----KAPSTSHSGF 573 K P++ KK P +P ++ K ++ AA KP+ K Sbjct: 733 KKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKKDSVAAGKPKEKGKIKVIKKEGKAA 792 Query: 574 PPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEE----KALELPLA 629 VA + + A+ AA G PA +L A SL P ++ KA E+ + Sbjct: 793 EAVAAAVGTGATTAAVMAAAGIAAIG-PAKELEAERSLMSSPEDLTKDFEELKAEEVDVT 851 Query: 630 ASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASP 670 P+ E E E + R GP SP Sbjct: 852 KDIKPQLELIEDEEKLKETEPVEAYVIQKEREVTKGPAESP 892 >gi|95147555 microtubule-associated protein 1A [Homo sapiens] Length = 2803 Score = 293 bits (750), Expect = 6e-79 Identities = 182/392 (46%), Positives = 230/392 (58%), Gaps = 55/392 (14%) Query: 205 EGLCEFLEYVAESLEPPSPFELLEPPTSGGFLRLGRPCCYIFPGGLGDAAFFAVNGFTVL 264 +G+ EF EYV+E+++ PSPF+LLEPPTSGGFL+L +PCCYIFPGG GD+A FAVNGF +L Sbjct: 2 DGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNIL 61 Query: 265 VNGGSNPKSSFWKLVRHLDRVDAVLVTHPGADSLPGLNSLLRRKLAE-RSEVAAGGGSWD 323 V+GGS+ KS FWKLVRHLDR+D+VL+TH GAD+LPG+N LL+RK+AE E + G S+ Sbjct: 62 VDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYS 121 Query: 324 DRLRRLISPNLGVVFFNACE------AASRLARGEDEAELALSLLAQLGITPLPLSR-GP 376 D ++ LISP LGVVFFN E A+ + R +EA L L L +LGI PL R Sbjct: 122 DWVKNLISPELGVVFFNVPEKLRLPDASRKAKRSIEEACLTLQHLNRLGIQAEPLYRVVS 181 Query: 377 VPAKPTVLFEKMGVGRLDMYVLHPPSAGAERT---------------------------- 408 +P LF KMGVGRLDMYVL+P E Sbjct: 182 NTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEISV 241 Query: 409 --LASVCALLVWHPAGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEG 466 L S+ AL+VW PA P EK+VRVLFPG P +L+GL +L+HL FLR PV T +DL Sbjct: 242 PYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLAS 301 Query: 467 PG------------RAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRK 514 RA+SKES+ + LA +E AR E A+ A K Sbjct: 302 GAVPTNLKPSKIKQRADSKESL-KATTKTAVSKLAKREEVVEEGAKEARSELAKELA--K 358 Query: 515 TEKEAKTPREL--KKDPKPSVSRTQPREVRRA 544 TEK+AK E +K KP +T+ E +A Sbjct: 359 TEKKAKESSEKPPEKPAKPERVKTESSEALKA 390 Score = 196 bits (498), Expect = 1e-49 Identities = 194/602 (32%), Positives = 259/602 (43%), Gaps = 140/602 (23%) Query: 566 PSTSHSGFPPVANGPR-SPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKAL 624 PS S G P ++N PR + P+L G +S + S ++ + PSLE +GE Sbjct: 2234 PSPSSPGAPLLSNLPRPASPALSEGSSSEATTPVISSVAERFS-PSLEAAEQESGELDPG 2292 Query: 625 ELPLAASSIP-RPRTPSPESHRSPAEGSERLSLSPLRGGEAG------------------ 665 P A S P +P+P PA L+ +P G+ G Sbjct: 2293 MEPAAHSLWDLTPLSPAP-----PASLDLALAPAPSLPGDMGDGILPCHLECSEAATEKP 2347 Query: 666 -----PDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSF----------------EQ 704 P PT T+P+ P +P E +E+ + + Sbjct: 2348 SPFQVPSEDCAANGPTETSPNPPGP--APAKAENEEAAACPAWERGAWPEGAERSSRPDT 2405 Query: 705 VLPPSAPTSEAGLSLPLRGPRARRSASPHDVDL----CLVSPCEFEHRKAV-PMAPAPAS 759 +L P P AG S GP + SASP +V+ C P HR + P P Sbjct: 2406 LLSPEQPVCPAGGS---GGPPS--SASP-EVEAGPQGCATEPRP--HRGELSPSFLNPPL 2457 Query: 760 PGSSNDSSARSQE----------RAGGLGA--------EETPPTSVSESLPTLSDSDPVP 801 P S +D ++E R GG G +ETPPTS S+S + SDSD P Sbjct: 2458 PPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPP 2517 Query: 802 --------LAPGAADSDEDTEGFGV-------------PRHDPLPDPLKVPPPLPDPSSI 840 A A DSDED + V P HDP P P P P P + Sbjct: 2518 ETEECPSITAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDV 2577 Query: 841 CMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAK----------TKGLA 890 CM DPE L ++ R E + K R RA KA P + A+ T G Sbjct: 2578 CMADPEGLSSESGR-VERLREKEKVQGRVGRRAPG-KAKPASPARRLDLRGKRSPTPGKG 2635 Query: 891 GGDRASR----PLSARSEPS---EKGGRAPLSR------KSSTPKTATRGPSGSASSRPG 937 DRASR P S S+ + EK G +P+S+ K+ +++G SG+ Sbjct: 2636 PADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVNGLKAGPMALSSKGSSGA------ 2689 Query: 938 VSATPPKSPVYLDLAYLPSGSSAHLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALL 997 PVY+DLAY+P+ S D +FF+RVRA YV+SG D E RAVLDALL Sbjct: 2690 --------PVYVDLAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALL 2741 Query: 998 ASKQHWDRDLQVTLIPTFDSVAMHTWYAETHARHQALGITVLGSNSMVSMQDDAFPACKV 1057 K W +LQVTLIPT D+ WY +TH + Q L + VL S+S V MQD++FPACK+ Sbjct: 2742 EGKAQWGENLQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSSTVVMQDESFPACKI 2801 Query: 1058 EF 1059 EF Sbjct: 2802 EF 2803 Score = 50.8 bits (120), Expect = 7e-06 Identities = 123/497 (24%), Positives = 173/497 (34%), Gaps = 103/497 (20%) Query: 503 RKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVR----------RAASSVPNLK 552 R+E RAEAP K+ +K P K +T+P + + A + Sbjct: 1916 REEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMM 1975 Query: 553 KTNAQAAPKPRKAPSTSHSGFPPV-----------------ANGPRSPPSLRCGEASPPS 595 T A R+ P + +PP + P SP SL+ + Sbjct: 1976 LTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSY 2035 Query: 596 AACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLS 655 AA P P E GP ++E L ++P PR P SP LS Sbjct: 2036 AALAGP----TVPPRPEPGP-------SMEPSLTPPAVP-PRAPILSKGPSPPLNGNILS 2083 Query: 656 LSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPT--- 712 SP R + ++ + + + L E G+ E E+ S S +P +PT Sbjct: 2084 CSPDRRSPSPKESGRSHWDDSTSDSEL--EKGAREQPE-KEAQSPSPPHPIPMGSPTLWP 2140 Query: 713 -SEAGLSLPL---RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSN-DSS 767 +EA +S PL GP AR S +D + + A P P+PA P S+ S Sbjct: 2141 ETEAHVSPPLDSHLGP-ARPS-----LDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSL 2194 Query: 768 ARSQERAGGLG------------AEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEG 815 A S +RA L E T S+ SLP L P P +PGA Sbjct: 2195 AFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQL----PSPSSPGA--------- 2241 Query: 816 FGVPRHDPLPDPLKVPPPLPDPSSICMVDP------EMLPPKTARQTENVSRTRKPLARP 869 P LP P P L + SS P E P + E S P P Sbjct: 2242 ---PLLSNLPRP--ASPALSEGSSSEATTPVISSVAERFSP-SLEAAEQESGELDPGMEP 2295 Query: 870 NSRA---------AAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSST 920 + + A P + +A A L GD L E SE P + + Sbjct: 2296 AAHSLWDLTPLSPAPPASLDLALAPAPSLP-GDMGDGILPCHLECSEAATEKPSPFQVPS 2354 Query: 921 PKTATRGPSGSASSRPG 937 A GP+ ++ + PG Sbjct: 2355 EDCAANGPTETSPNPPG 2371 Score = 42.7 bits (99), Expect = 0.002 Identities = 103/476 (21%), Positives = 164/476 (34%), Gaps = 89/476 (18%) Query: 512 PRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHS 571 P TE+ T + D + V + AS + ++++ Q + + + S Sbjct: 1719 PHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPV 1778 Query: 572 GFPP------------VANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLE------- 612 G PP + + P SPP + G+ P + SP P ++ Sbjct: 1779 GLPPEEEDKLTRSPFEIISPPASPPEM-VGQRVPSAPGQESPIPDPKLMPHMKNEPTTPS 1837 Query: 613 -LGPIPAGEEKALELPLAA-SSIPRPRTPSPESHRSPAE------------GSERLSLSP 658 L IP K LP A S P P TP+PESH +PA + + + Sbjct: 1838 WLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESH-TPAPFSWGTAEYDSVVAAVQEGAAE 1896 Query: 659 LRGGEAGPDASPTVTTPTVTTPSLPAEV--GSPHSTEVDESLSVSFEQVLPPSAPTSEAG 716 L GG P AE S HS++V E+ S T+E Sbjct: 1897 LEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEA---------SKSHATTE-- 1945 Query: 717 LSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPA------PASPGSSNDSSARS 770 P + +R +P+ + +E + PA P + Sbjct: 1946 ---PEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLST 2002 Query: 771 QERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKV 830 +E A G TS + L + P++P + SD T + L P Sbjct: 2003 KEAAAGRN------TSAEKELSS-------PISPKSLQSDTPTFSYAA-----LAGPTVP 2044 Query: 831 PPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAP-KATPVAAAKTKGL 889 P P P PS ++P + PP + +S+ P N + +P + +P + K G Sbjct: 2045 PRPEPGPS----MEPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPDRRSP--SPKESGR 2098 Query: 890 AGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSA--TPP 943 + D S EKG R +++ +P P GS + P A +PP Sbjct: 2099 SHWDD-----STSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPP 2149 Score = 30.8 bits (68), Expect = 7.1 Identities = 27/124 (21%), Positives = 57/124 (45%), Gaps = 6/124 (4%) Query: 464 LEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPR 523 L+ R K+ VG + ++ L ++ RKE + E ++ +K+AK Sbjct: 388 LKAEKRKLIKDKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKK-E 446 Query: 524 ELKKDPKPSVSRTQPREVRRAASSVPNLKKT--NAQAAPKPRKAPSTSHSGFPPVANGPR 581 E +KD KP + + +++ P ++KT A+ + + S + G +++ P+ Sbjct: 447 EKRKDTKPELKKISKPDLK---PFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQ 503 Query: 582 SPPS 585 +PP+ Sbjct: 504 TPPA 507 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 92.0 bits (227), Expect = 3e-18 Identities = 133/493 (26%), Positives = 171/493 (34%), Gaps = 79/493 (16%) Query: 489 ATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSV 548 AT P P + G A P A P P PK + P+ + Sbjct: 968 ATPPSP---KGGPATPSPKGAPTP---------PAATPPSPKGGPATPSPKGAPTPPAVT 1015 Query: 549 PNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVAT 608 P K + A P P K ST + PP G + L G + P+A SP AT Sbjct: 1016 PPSPKGSPAATPFP-KGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG-PAT 1073 Query: 609 PSLELGPIPAGEEKALELPLAASSIPR--PRTPSPESHRSPAEGSERLSLSPLRGGEAGP 666 PSL+ P P P A P+ P TPSP+ P + SP +GG A P Sbjct: 1074 PSLKGAPTP---------PAATPPSPKGGPATPSPKGAPMPPAATPP---SP-KGGLATP 1120 Query: 667 DASPTVTTPTVTTPS------LPAEVGSPHS-TEVDESLSVSFEQVLPPSAPTSEA---- 715 TTP T PS P G+P + S P APT+ A Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180 Query: 716 ----GLSLPL-RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARS 770 GL+ P +G +A+P L +P K P PA A+P S A Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP----KGAPTTPA-ATPPSPKGGLATP 1235 Query: 771 QERAGGLGAEETPPTSVSESLPTLSDSDPVPL---APGAADSDEDTEGFGVPRHDPLPDP 827 + TPP+ P + P P P AA G P H P+P Sbjct: 1236 SPKGAPTTPAATPPS------PKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP 1289 Query: 828 LKVPPPLP--DPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAA---APKATPVA 882 V PP P P++ P T + T P P A +PK TP Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL 1349 Query: 883 AAKTKGLAGG----DRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPS-----GSAS 933 A T GG P + PS KGG A TP + RGP+ G + Sbjct: 1350 PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPA------MTPPSPKRGPAIPSPKGDPT 1403 Query: 934 SRPGVSATPPKSP 946 S + +P K+P Sbjct: 1404 SPAVIPLSPKKAP 1416 Score = 85.9 bits (211), Expect = 2e-16 Identities = 134/573 (23%), Positives = 200/573 (34%), Gaps = 68/573 (11%) Query: 420 PAGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEG----PGRAESKES 475 PA P K + P TPP+ GL H P TP +G P + + Sbjct: 1094 PATPSPKGAPMP-PAATPPSPK-GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151 Query: 476 VGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSR 535 + S + GL P+ P P A + TP PK ++ Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1211 Query: 536 TQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPP----------- 584 P+ ++ P K A P P+ AP+T + P GP +PP Sbjct: 1212 PSPKGAPTTPAATPPSPK-GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270 Query: 585 --SLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPR--PRTPS 640 SL+ G A+PP +PA +V PS + GP + + A P A P+ P TP Sbjct: 1271 PPSLKGGLATPPHKGAPNPA--VVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPP 1328 Query: 641 PESHRSPA-------EGSERLSLSP--LRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHS 691 P+ +P +G+ L + +GG P + T P T P+ G P Sbjct: 1329 PKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAAT----PSHKGGPAM 1384 Query: 692 TEVDESLSVSFEQVLPPSAPTSEAGLSL-PLRGPRA----RRSASPHDVDLC--LVSPCE 744 T + P PTS A + L P + P +A+P DL V+P Sbjct: 1385 TPPSPKRGPAIPS--PKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVS 1442 Query: 745 FEHRKAVPMAP--APASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPL 802 + A AP PA+P S D + + P + S P + + P P+ Sbjct: 1443 LKKAPATS-APKGGPATPSSKGDPTLPAVTPPSPK-EPPAPKQVATSSSPKKAPATPAPM 1500 Query: 803 APGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRT 862 + + P+ P + P P + + P L PK A ++ Sbjct: 1501 GAPTLPAVIPSS----PKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMT-- 1554 Query: 863 RKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPK 922 + P A P A + A A P + + PS K P + S +PK Sbjct: 1555 ---VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611 Query: 923 TATRGPS--------GSASSRP-GVSATPPKSP 946 A P+ G A+ P G +PP +P Sbjct: 1612 EAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644 Score = 82.4 bits (202), Expect = 2e-15 Identities = 123/427 (28%), Positives = 159/427 (37%), Gaps = 59/427 (13%) Query: 526 KKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPS 585 K+ P PSV P A+ P + + P+KA +T P G + PS Sbjct: 883 KETPTPSVVNL-PFPKEGPATPAPKQAPALSMTSSSPKKARAT------PAPKGIPASPS 935 Query: 586 LRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPR--PRTPSPES 643 + G +PP+A SP ATPS + P P P A P+ P TPSP+ Sbjct: 936 PK-GAPTPPAATPPSPKGG-PATPSPKWAPTP---------PAATPPSPKGGPATPSPKG 984 Query: 644 HRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFE 703 +P + SP +GG A P T P VT PS GSP +T + S Sbjct: 985 APTPPAATPP---SP-KGGPATPSPKGAPTPPAVTPPS---PKGSPAATPFPKGASTP-P 1036 Query: 704 QVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAP--ASPG 761 PPS S A LP P + P SP ++ AP P A+P Sbjct: 1037 AATPPSPKGSPAATPLPKGAPTTPAATLP--------SPKGGPATPSLKGAPTPPAATPP 1088 Query: 762 SSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRH 821 S A + + TPP S L T P P AA G P Sbjct: 1089 SPKGGPATPSPKGAPMPPAATPP-SPKGGLAT-PPHKGAPTTP-AATPPSPKGGLATPPP 1145 Query: 822 DPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVS--RTRKPLARPNSRAA--APK 877 P PP P + P PPK A T + + LA P+ + A P Sbjct: 1146 KGAPTTPAATPPSPKGG---LATP---PPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1199 Query: 878 ATPVAAAKTKGLAGGDRASRPLS-ARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRP 936 ATP + GLA P + A + PS KGG A + +PK A P+ + S Sbjct: 1200 ATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGLA-----TPSPKGAPTTPAATPPSPK 1252 Query: 937 GVSATPP 943 G ATPP Sbjct: 1253 GGPATPP 1259 Score = 65.1 bits (157), Expect = 3e-10 Identities = 146/631 (23%), Positives = 223/631 (35%), Gaps = 90/631 (14%) Query: 339 FNACEAASRLARGEDEAELALSLLAQL-----GITPLPLSRG-PVPAKPTVLFEKMGVGR 392 F+ S + + A L+AQ+ G TPL ++ + A PT FE Sbjct: 405 FSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFE------ 458 Query: 393 LDMYVLHPPSAGAERTLASVC-ALLVWHPAGPGE---KVVRVLFPGCTPPACLLDGLVRL 448 + V P S+G + A LV P P E +V L +PP + L L Sbjct: 459 VATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNL 518 Query: 449 QHLRFLREPV-----VTPQDLEGPGRAESKESVGSRDSSKREGLLATHPR--PGQERPGV 501 ++ P P LEG + ++ + ++ L+ P+ P + Sbjct: 519 PSSVLVKFPTQKDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSS 578 Query: 502 ARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPK 561 + + P EA +K P + K P+ S T P V +AS + KT++ A P Sbjct: 579 SPEIPLSPEATL-AKKSLGEPLPIGK---PASSMTSPLGVNSSASVI----KTDSYAGPD 630 Query: 562 PRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLE----LGPI- 616 S P VA P G A P+ A G+ A+P LE L P Sbjct: 631 SAGPLLKSSLITPTVAAFPLESAD-PAGVA--PTTAKGTSTYTTTASPFLEGTVSLAPKN 687 Query: 617 -PAGEEKALELPLAASSIPR-PRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTT 674 P E LPL ++ P PSP++ +P L L+P Sbjct: 688 HPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLA---TLVLAP-------------EIP 731 Query: 675 PTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHD 734 +V +PSLP P + +VD +S L AP + + P A +AS Sbjct: 732 KSVPSPSLPPAGTPPGTKKVD---GISHTSAL---APVASSPKECPTEDSGASATASSKG 785 Query: 735 VDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTL 794 +A +P+ G S + G +TP ++S + + Sbjct: 786 T--------------LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPV 831 Query: 795 SDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPE--MLPPKT 852 S P + S + ++ H P P P P PS++ + P+ LPPK Sbjct: 832 EAS----FLPENSLSFQGSKDSPATTHSPTPPS---PKGAPTPSAVTPLSPKGVTLPPK- 883 Query: 853 ARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRA 912 +T S P + APK P + + P + PS KG Sbjct: 884 --ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPT 941 Query: 913 PLSRKSSTPKTATRGPSGSASSRPGVSATPP 943 P + +PK PS + P +ATPP Sbjct: 942 PPAATPPSPKGGPATPSPKWAPTP-PAATPP 971 Score = 60.8 bits (146), Expect = 6e-09 Identities = 120/489 (24%), Positives = 169/489 (34%), Gaps = 122/489 (24%) Query: 454 LREPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPR 513 L P VTP L+ + + + SSK + L P + P A K+ A + +P+ Sbjct: 1433 LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPP-APKQVATSSSPK 1491 Query: 514 KTEKEAKTPRELKKDPKPSVSRTQPREVRRAASS-------------------------- 547 K TP + P+V + P+EV SS Sbjct: 1492 KAPA---TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEAL 1548 Query: 548 ------VPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSP 601 VP+ KKT A P P++AP+T P + SPP A PS G+P Sbjct: 1549 IPPAMTVPSPKKT--PAIPTPKEAPAT------PSSKEASSPP------AVTPSTYKGAP 1594 Query: 602 ASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRG 661 + + + P P P A + P PSPE Sbjct: 1595 SPKELLIPPAVTSPSPK----------EAPTPPAVTPPSPEK------------------ 1626 Query: 662 GEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPL 721 G A P T T+P VT SL SP S +V P + GL Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATV----------PQASKGLPAK- 1675 Query: 722 RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPG-SSNDSSARSQERAGGLGAE 780 +GP A + LV+P ++ P+ AP G + SSA S Sbjct: 1676 KGPTALKEV--------LVAPAP----ESTPIITAPTRKGPQTKKSSATSPPIC------ 1717 Query: 781 ETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSI 840 P++ + S LS P PL P DS + +G H P PL PP + + Sbjct: 1718 -PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDA-SHSP-KGPL-APPESKASTPL 1773 Query: 841 CMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGG-----DRA 895 E + PK ++ +VS P P S AP P K + L + Sbjct: 1774 TAAAFEKVLPKP--ESASVSAAPSP---PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESP 1828 Query: 896 SRPLSARSE 904 S+PL+ E Sbjct: 1829 SKPLAPADE 1837 Score = 33.1 bits (74), Expect = 1.4 Identities = 82/383 (21%), Positives = 125/383 (32%), Gaps = 69/383 (18%) Query: 595 SAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERL 654 +AA G P P+L PA ++ L AS P P T + P S Sbjct: 35 TAALGQPG------PTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSG 88 Query: 655 SLSPLRGGEAGPDASPTVTTPTVT-----------------TPSLPAEVG----SPHSTE 693 + PL P P + P ++ TPS A + +PHS + Sbjct: 89 TALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQ 148 Query: 694 VDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPM 753 + + PPS +E+G + L P A S +L V + K P Sbjct: 149 KSSAFPPNL-LTSPPSVAVAESGSVITLSAPIA---PSEPKTNLNKVPSEVVPNPKGTPS 204 Query: 754 APAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDT 813 P S + TP S+ + +L + P A+ +DT Sbjct: 205 PPCIVSTVPYHC---------------VTPMASIQSGVASLPQTTPTTTLAIASPQVKDT 249 Query: 814 EGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPN--- 870 V P L + P+ P+++ + + LP T+ Q +T P P+ Sbjct: 250 TISSVLISPQNPGSLSLKGPVSPPAALSL-STQSLPVVTSSQ-----KTAGPNTPPDFPI 303 Query: 871 ---SRAAAPKATPVAAAKTKGLAGGDRASRPL----------SARSEPSEKGGRAPL-SR 916 S A + + + G G S P + S PS++ PL SR Sbjct: 304 SLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSR 363 Query: 917 KSSTPKTATRGPSGSASSRPGVS 939 P T P + S G S Sbjct: 364 NEVVPATVAAFPVVAPSVDKGPS 386 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 90.1 bits (222), Expect = 1e-17 Identities = 106/495 (21%), Positives = 167/495 (33%), Gaps = 68/495 (13%) Query: 504 KEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPR 563 KEPA T K+ K+P P+ +++ P + A P K A PK Sbjct: 222 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPK-E 277 Query: 564 KAPSTSHSGFPPVANG----PRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAG 619 AP+T+ P P+ P + +P + +P + TP+ P P Sbjct: 278 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337 Query: 620 EEKALELPL----AASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTP 675 +E A P A P P TP + +P E + + P P + T + P Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397 Query: 676 T-------VTTPSLPAEVGSPHSTEVDESLSVSFEQVLP-------PSAPTSEAGLSLPL 721 T TT S P P T E + ++ P P+ P A + Sbjct: 398 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 457 Query: 722 RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEE 781 P + +P P ++ P P +P + + + E+ EE Sbjct: 458 PAPTTTKKPAPTTPK----EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 513 Query: 782 TPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPL------- 834 PT+ E PT + +P P P AA + E +P P K P P Sbjct: 514 LAPTTPEEPTPT-TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572 Query: 835 -------------PDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPV 881 P P++ P+ L P T ++ + + + P A P Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632 Query: 882 AAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPK----TATRGPSGSASSRPG 937 + + + P + + EP AP + K PK T T+GP+ + S +P Sbjct: 633 PTTPKEPAPTTPKGTAPTTLK-EP------APTTPKKPAPKELAPTTTKGPTSTTSDKPA 685 Query: 938 ------VSATPPKSP 946 + T PK P Sbjct: 686 PTTPKETAPTTPKEP 700 Score = 69.7 bits (169), Expect = 1e-11 Identities = 98/443 (22%), Positives = 150/443 (33%), Gaps = 64/443 (14%) Query: 494 PGQERPGVARKEPARAE--APRKTEKEAKTPRE----LKKDPKPSVSRTQ-PREVRRAAS 546 P + P + P + AP T+ TP+E K+P P+ + P ++ A Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 444 Query: 547 SVPNLKKTNAQAAPKP----RKAPSTSHSGFP--PVANGPRSPPSLRCGEASPPSAACGS 600 + P P P + AP+T P P P +P L +P A + Sbjct: 445 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT--PTTPEKLAPTT 502 Query: 601 PASQLVATPSLELGPIP-------AGEEKALELPLAAS-SIPRPRTPSPESHRSPAEGSE 652 P TP EL P EE A P AA+ + P+ P+ +P E Sbjct: 503 PEKPAPTTPE-ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 561 Query: 653 RLSLSPLRGGEAGP--DASPTVTTPTVTTPSLPA-------EVGSPHSTEVDESLSVSFE 703 +P P A T+ P TTP PA P ST D+ + + Sbjct: 562 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621 Query: 704 QVLP---------------PSAPTSEAGLSLPLRGPRARRSASPHDV-DLCLVSPCEFEH 747 P P+ P A +L P + +P ++ P Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681 Query: 748 RKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAA 807 K P P +P + + + + ++ E PPT+ S PT + +P + Sbjct: 682 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPD 740 Query: 808 DSDEDTEGFGVPRHDPLPDPLK---VPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRK 864 +S + +P P L+ P +P + PEM + TE RT Sbjct: 741 ESTPELSA------EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-- 792 Query: 865 PLARPNSRAAAPKATPVAAAKTK 887 P + AAPK T A T+ Sbjct: 793 ---TPETTTAAPKMTKETATTTE 812 Score = 67.4 bits (163), Expect = 7e-11 Identities = 101/500 (20%), Positives = 163/500 (32%), Gaps = 50/500 (10%) Query: 492 PRPGQERPGVARKEPARAEAPRKTEKEAKTPRE----LKKDPKPSVSR----TQPREVRR 543 P +E KEPA P E TP+E K P P+ + T P+E Sbjct: 319 PTTPKEPTPTTPKEPA----PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 374 Query: 544 AASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANG----PRSPPSLRCGEASPPSAACG 599 + P+ A + AP+T+ P P+ P E +P + Sbjct: 375 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 434 Query: 600 SPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPL 659 +P + P+ P P ++ + P+ P+P + + A + + L+P Sbjct: 435 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPT 493 Query: 660 RGGEAGPDA--SPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLP-------PSA 710 + P P TTP P+ P E P T +E + + P P+ Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEE---PTPTTPEEPAPTTPKAAAPNTPKEPAPTT 550 Query: 711 PTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAP--ASPGSSNDSSA 768 P A + P + +P + + E P PAP +P ++ + ++ Sbjct: 551 PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTS 609 Query: 769 RSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPL 828 + ++ + T PT+ E PT + +P P P E P P L Sbjct: 610 TTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 668 Query: 829 KVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKG 888 P P+S P PK E T K A + AP T Sbjct: 669 -APTTTKGPTSTTSDKPAPTTPK-----ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 722 Query: 889 LAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGP--------SGSASSRPGVSA 940 ++ P + P E P TPK P A+++P ++ Sbjct: 723 VSTPTTTKEPTTIHKSPDES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 779 Query: 941 TPPKSPVYLDLAYLPSGSSA 960 T DL P ++A Sbjct: 780 TAKDKTTERDLRTTPETTTA 799 Score = 48.5 bits (114), Expect = 3e-05 Identities = 63/277 (22%), Positives = 100/277 (36%), Gaps = 34/277 (12%) Query: 670 PTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRS 729 P +TTP TP+ P E P ST E + + SAPT+ P+ Sbjct: 208 PALTTPKEPTPTTPKE---PASTTPKEPTPTTIK-----SAPTT----------PKEPAP 249 Query: 730 ASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSE 789 + P ++ P P +P ++ + A + ++ +E PT+ + Sbjct: 250 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-PAPTTTKSAPTTPKEPAPTTPKK 308 Query: 790 SLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLP 849 PT + +P P P E + +P P K P P P P+ Sbjct: 309 PAPT-TPKEPAPTTPKEPTPTTPKEPAPTTK-EPAPTTPKEPAPTA-PKKPAPTTPKEPA 365 Query: 850 PKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKG 909 P T + E T K + + AP T A TK A P + +S P+ Sbjct: 366 PTTPK--EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-------PTTTKSAPTTPK 416 Query: 910 GRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSP 946 +P + K P T + P+ + +P + T PK P Sbjct: 417 EPSPTTTKEPAP-TTPKEPAPTTPKKP--APTTPKEP 450 Score = 47.4 bits (111), Expect = 7e-05 Identities = 47/195 (24%), Positives = 73/195 (37%), Gaps = 20/195 (10%) Query: 504 KEPARA--EAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPK 561 KEPA + P T + P LK+ + + P+E+ + P ++ A Sbjct: 629 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 688 Query: 562 PRK-APSTSHSGFP-----PVANGPRSPPSLRCGEASP-----PSAACGSPASQLVATPS 610 P++ AP+T P P P +PP ++P P+ SP +TP Sbjct: 689 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE---STPE 745 Query: 611 LELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASP 670 L P P KALE +P +TP+ ++ + LR A+P Sbjct: 746 LSAEPTP----KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 801 Query: 671 TVTTPTVTTPSLPAE 685 +T T TT E Sbjct: 802 KMTKETATTTEKTTE 816 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 90.1 bits (222), Expect = 1e-17 Identities = 106/495 (21%), Positives = 167/495 (33%), Gaps = 68/495 (13%) Query: 504 KEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPR 563 KEPA T K+ K+P P+ +++ P + A P K A PK Sbjct: 263 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPK-E 318 Query: 564 KAPSTSHSGFPPVANG----PRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAG 619 AP+T+ P P+ P + +P + +P + TP+ P P Sbjct: 319 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378 Query: 620 EEKALELPL----AASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTP 675 +E A P A P P TP + +P E + + P P + T + P Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438 Query: 676 T-------VTTPSLPAEVGSPHSTEVDESLSVSFEQVLP-------PSAPTSEAGLSLPL 721 T TT S P P T E + ++ P P+ P A + Sbjct: 439 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 498 Query: 722 RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEE 781 P + +P P ++ P P +P + + + E+ EE Sbjct: 499 PAPTTTKKPAPTTPK----EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 554 Query: 782 TPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPL------- 834 PT+ E PT + +P P P AA + E +P P K P P Sbjct: 555 LAPTTPEEPTPT-TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613 Query: 835 -------------PDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPV 881 P P++ P+ L P T ++ + + + P A P Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673 Query: 882 AAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPK----TATRGPSGSASSRPG 937 + + + P + + EP AP + K PK T T+GP+ + S +P Sbjct: 674 PTTPKEPAPTTPKGTAPTTLK-EP------APTTPKKPAPKELAPTTTKGPTSTTSDKPA 726 Query: 938 ------VSATPPKSP 946 + T PK P Sbjct: 727 PTTPKETAPTTPKEP 741 Score = 69.7 bits (169), Expect = 1e-11 Identities = 98/443 (22%), Positives = 150/443 (33%), Gaps = 64/443 (14%) Query: 494 PGQERPGVARKEPARAE--APRKTEKEAKTPRE----LKKDPKPSVSRTQ-PREVRRAAS 546 P + P + P + AP T+ TP+E K+P P+ + P ++ A Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 485 Query: 547 SVPNLKKTNAQAAPKP----RKAPSTSHSGFP--PVANGPRSPPSLRCGEASPPSAACGS 600 + P P P + AP+T P P P +P L +P A + Sbjct: 486 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT--PTTPEKLAPTT 543 Query: 601 PASQLVATPSLELGPIP-------AGEEKALELPLAAS-SIPRPRTPSPESHRSPAEGSE 652 P TP EL P EE A P AA+ + P+ P+ +P E Sbjct: 544 PEKPAPTTPE-ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 602 Query: 653 RLSLSPLRGGEAGP--DASPTVTTPTVTTPSLPA-------EVGSPHSTEVDESLSVSFE 703 +P P A T+ P TTP PA P ST D+ + + Sbjct: 603 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662 Query: 704 QVLP---------------PSAPTSEAGLSLPLRGPRARRSASPHDV-DLCLVSPCEFEH 747 P P+ P A +L P + +P ++ P Sbjct: 663 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722 Query: 748 RKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAA 807 K P P +P + + + + ++ E PPT+ S PT + +P + Sbjct: 723 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPD 781 Query: 808 DSDEDTEGFGVPRHDPLPDPLK---VPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRK 864 +S + +P P L+ P +P + PEM + TE RT Sbjct: 782 ESTPELSA------EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-- 833 Query: 865 PLARPNSRAAAPKATPVAAAKTK 887 P + AAPK T A T+ Sbjct: 834 ---TPETTTAAPKMTKETATTTE 853 Score = 67.4 bits (163), Expect = 7e-11 Identities = 101/500 (20%), Positives = 163/500 (32%), Gaps = 50/500 (10%) Query: 492 PRPGQERPGVARKEPARAEAPRKTEKEAKTPRE----LKKDPKPSVSR----TQPREVRR 543 P +E KEPA P E TP+E K P P+ + T P+E Sbjct: 360 PTTPKEPTPTTPKEPA----PTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP 415 Query: 544 AASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANG----PRSPPSLRCGEASPPSAACG 599 + P+ A + AP+T+ P P+ P E +P + Sbjct: 416 TTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEP 475 Query: 600 SPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPL 659 +P + P+ P P ++ + P+ P+P + + A + + L+P Sbjct: 476 APTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPK-KLTPT 534 Query: 660 RGGEAGPDA--SPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLP-------PSA 710 + P P TTP P+ P E P T +E + + P P+ Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEE---PTPTTPEEPAPTTPKAAAPNTPKEPAPTT 591 Query: 711 PTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAP--ASPGSSNDSSA 768 P A + P + +P + + E P PAP +P ++ + ++ Sbjct: 592 PKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK-EPAPTTPKKPAPKELAPTTTKEPTS 650 Query: 769 RSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPL 828 + ++ + T PT+ E PT + +P P P E P P L Sbjct: 651 TTCDKPAPTTPKGTAPTTPKEPAPT-TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 709 Query: 829 KVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKG 888 P P+S P PK E T K A + AP T Sbjct: 710 -APTTTKGPTSTTSDKPAPTTPK-----ETAPTTPKEPAPTTPKKPAPTTPETPPPTTSE 763 Query: 889 LAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGP--------SGSASSRPGVSA 940 ++ P + P E P TPK P A+++P ++ Sbjct: 764 VSTPTTTKEPTTIHKSPDES---TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTT 820 Query: 941 TPPKSPVYLDLAYLPSGSSA 960 T DL P ++A Sbjct: 821 TAKDKTTERDLRTTPETTTA 840 Score = 48.5 bits (114), Expect = 3e-05 Identities = 63/277 (22%), Positives = 100/277 (36%), Gaps = 34/277 (12%) Query: 670 PTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRS 729 P +TTP TP+ P E P ST E + + SAPT+ P+ Sbjct: 249 PALTTPKEPTPTTPKE---PASTTPKEPTPTTIK-----SAPTT----------PKEPAP 290 Query: 730 ASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSE 789 + P ++ P P +P ++ + A + ++ +E PT+ + Sbjct: 291 TTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE-PAPTTTKSAPTTPKEPAPTTPKK 349 Query: 790 SLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLP 849 PT + +P P P E + +P P K P P P P+ Sbjct: 350 PAPT-TPKEPAPTTPKEPTPTTPKEPAPTTK-EPAPTTPKEPAPTA-PKKPAPTTPKEPA 406 Query: 850 PKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKG 909 P T + E T K + + AP T A TK A P + +S P+ Sbjct: 407 PTTPK--EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA-------PTTTKSAPTTPK 457 Query: 910 GRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSP 946 +P + K P T + P+ + +P + T PK P Sbjct: 458 EPSPTTTKEPAP-TTPKEPAPTTPKKP--APTTPKEP 491 Score = 47.4 bits (111), Expect = 7e-05 Identities = 47/195 (24%), Positives = 73/195 (37%), Gaps = 20/195 (10%) Query: 504 KEPARA--EAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPK 561 KEPA + P T + P LK+ + + P+E+ + P ++ A Sbjct: 670 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 729 Query: 562 PRK-APSTSHSGFP-----PVANGPRSPPSLRCGEASP-----PSAACGSPASQLVATPS 610 P++ AP+T P P P +PP ++P P+ SP +TP Sbjct: 730 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE---STPE 786 Query: 611 LELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASP 670 L P P KALE +P +TP+ ++ + LR A+P Sbjct: 787 LSAEPTP----KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 842 Query: 671 TVTTPTVTTPSLPAE 685 +T T TT E Sbjct: 843 KMTKETATTTEKTTE 857 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 90.1 bits (222), Expect = 1e-17 Identities = 106/495 (21%), Positives = 167/495 (33%), Gaps = 68/495 (13%) Query: 504 KEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPR 563 KEPA T K+ K+P P+ +++ P + A P K A PK Sbjct: 315 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPK-E 370 Query: 564 KAPSTSHSGFPPVANG----PRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAG 619 AP+T+ P P+ P + +P + +P + TP+ P P Sbjct: 371 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 430 Query: 620 EEKALELPL----AASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTP 675 +E A P A P P TP + +P E + + P P + T + P Sbjct: 431 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490 Query: 676 T-------VTTPSLPAEVGSPHSTEVDESLSVSFEQVLP-------PSAPTSEAGLSLPL 721 T TT S P P T E + ++ P P+ P A + Sbjct: 491 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 550 Query: 722 RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEE 781 P + +P P ++ P P +P + + + E+ EE Sbjct: 551 PAPTTTKKPAPTTPK----EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 606 Query: 782 TPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPL------- 834 PT+ E PT + +P P P AA + E +P P K P P Sbjct: 607 LAPTTPEEPTPT-TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665 Query: 835 -------------PDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPV 881 P P++ P+ L P T ++ + + + P A P Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725 Query: 882 AAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPK----TATRGPSGSASSRPG 937 + + + P + + EP AP + K PK T T+GP+ + S +P Sbjct: 726 PTTPKEPAPTTPKGTAPTTLK-EP------APTTPKKPAPKELAPTTTKGPTSTTSDKPA 778 Query: 938 ------VSATPPKSP 946 + T PK P Sbjct: 779 PTTPKETAPTTPKEP 793 Score = 69.7 bits (169), Expect = 1e-11 Identities = 98/443 (22%), Positives = 150/443 (33%), Gaps = 64/443 (14%) Query: 494 PGQERPGVARKEPARAE--APRKTEKEAKTPRE----LKKDPKPSVSRTQ-PREVRRAAS 546 P + P + P + AP T+ TP+E K+P P+ + P ++ A Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 537 Query: 547 SVPNLKKTNAQAAPKP----RKAPSTSHSGFP--PVANGPRSPPSLRCGEASPPSAACGS 600 + P P P + AP+T P P P +P L +P A + Sbjct: 538 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT--PTTPEKLAPTT 595 Query: 601 PASQLVATPSLELGPIP-------AGEEKALELPLAAS-SIPRPRTPSPESHRSPAEGSE 652 P TP EL P EE A P AA+ + P+ P+ +P E Sbjct: 596 PEKPAPTTPE-ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 654 Query: 653 RLSLSPLRGGEAGP--DASPTVTTPTVTTPSLPA-------EVGSPHSTEVDESLSVSFE 703 +P P A T+ P TTP PA P ST D+ + + Sbjct: 655 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714 Query: 704 QVLP---------------PSAPTSEAGLSLPLRGPRARRSASPHDV-DLCLVSPCEFEH 747 P P+ P A +L P + +P ++ P Sbjct: 715 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774 Query: 748 RKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAA 807 K P P +P + + + + ++ E PPT+ S PT + +P + Sbjct: 775 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPD 833 Query: 808 DSDEDTEGFGVPRHDPLPDPLK---VPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRK 864 +S + +P P L+ P +P + PEM + TE RT Sbjct: 834 ESTPELSA------EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-- 885 Query: 865 PLARPNSRAAAPKATPVAAAKTK 887 P + AAPK T A T+ Sbjct: 886 ---TPETTTAAPKMTKETATTTE 905 Score = 48.9 bits (115), Expect = 3e-05 Identities = 107/491 (21%), Positives = 166/491 (33%), Gaps = 81/491 (16%) Query: 470 AESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDP 529 +E++ES S SS + + ++ A E +K + + KK P Sbjct: 120 SENQESSSSSSSSSSSSTI--------RKIKSSKNSAANRELQKKLKVKDNKKNRTKKKP 171 Query: 530 KPSVSRTQPREVRRAASSVPN--LKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLR 587 P +P V A S + N K T + STS PR PSL Sbjct: 172 TP-----KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSL- 223 Query: 588 CGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSP 647 PP++ S V +E +E ++ + T E S Sbjct: 224 -----PPNSDTSKETSLTV------------NKETTVETKETTTTNKQTSTDGKEKTTSA 266 Query: 648 AEGS--ERLS---LSPLRGGEAGPDAS-------PTVTTPTVTTPSLPAEVGSPHSTEVD 695 E E+ S L+P A P P +TTP TP+ P E P ST Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE---PASTTPK 323 Query: 696 ESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAP 755 E + + SAPT+ P+ + P ++ P P Sbjct: 324 EPTPTTIK-----SAPTT----------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 368 Query: 756 APASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEG 815 +P ++ + A + ++ +E PT+ + PT + +P P P E Sbjct: 369 KEPAPTTTKE-PAPTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPTPTTPKEP 426 Query: 816 FGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAA 875 + +P P K P P P P+ P T + E T K + + A Sbjct: 427 APTTK-EPAPTTPKEPAPTA-PKKPAPTTPKEPAPTTPK--EPAPTTTKEPSPTTPKEPA 482 Query: 876 PKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSR 935 P T A TK A P + +S P+ +P + K P T + P+ + + Sbjct: 483 PTTTKSAPTTTKEPA-------PTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKK 534 Query: 936 PGVSATPPKSP 946 P + T PK P Sbjct: 535 P--APTTPKEP 543 Score = 47.4 bits (111), Expect = 7e-05 Identities = 47/195 (24%), Positives = 73/195 (37%), Gaps = 20/195 (10%) Query: 504 KEPARA--EAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPK 561 KEPA + P T + P LK+ + + P+E+ + P ++ A Sbjct: 722 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781 Query: 562 PRK-APSTSHSGFP-----PVANGPRSPPSLRCGEASP-----PSAACGSPASQLVATPS 610 P++ AP+T P P P +PP ++P P+ SP +TP Sbjct: 782 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE---STPE 838 Query: 611 LELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASP 670 L P P KALE +P +TP+ ++ + LR A+P Sbjct: 839 LSAEPTP----KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 894 Query: 671 TVTTPTVTTPSLPAE 685 +T T TT E Sbjct: 895 KMTKETATTTEKTTE 909 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 90.1 bits (222), Expect = 1e-17 Identities = 106/495 (21%), Positives = 167/495 (33%), Gaps = 68/495 (13%) Query: 504 KEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPR 563 KEPA T K+ K+P P+ +++ P + A P K A PK Sbjct: 356 KEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPA---PTTTKEPAPTTPK-E 411 Query: 564 KAPSTSHSGFPPVANG----PRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAG 619 AP+T+ P P+ P + +P + +P + TP+ P P Sbjct: 412 PAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 471 Query: 620 EEKALELPL----AASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTP 675 +E A P A P P TP + +P E + + P P + T + P Sbjct: 472 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531 Query: 676 T-------VTTPSLPAEVGSPHSTEVDESLSVSFEQVLP-------PSAPTSEAGLSLPL 721 T TT S P P T E + ++ P P+ P A + Sbjct: 532 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 591 Query: 722 RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEE 781 P + +P P ++ P P +P + + + E+ EE Sbjct: 592 PAPTTTKKPAPTTPK----EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 647 Query: 782 TPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPL------- 834 PT+ E PT + +P P P AA + E +P P K P P Sbjct: 648 LAPTTPEEPTPT-TPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706 Query: 835 -------------PDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPV 881 P P++ P+ L P T ++ + + + P A P Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766 Query: 882 AAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPK----TATRGPSGSASSRPG 937 + + + P + + EP AP + K PK T T+GP+ + S +P Sbjct: 767 PTTPKEPAPTTPKGTAPTTLK-EP------APTTPKKPAPKELAPTTTKGPTSTTSDKPA 819 Query: 938 ------VSATPPKSP 946 + T PK P Sbjct: 820 PTTPKETAPTTPKEP 834 Score = 69.7 bits (169), Expect = 1e-11 Identities = 98/443 (22%), Positives = 150/443 (33%), Gaps = 64/443 (14%) Query: 494 PGQERPGVARKEPARAE--APRKTEKEAKTPRE----LKKDPKPSVSRTQ-PREVRRAAS 546 P + P + P + AP T+ TP+E K+P P+ + P ++ A Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 578 Query: 547 SVPNLKKTNAQAAPKP----RKAPSTSHSGFP--PVANGPRSPPSLRCGEASPPSAACGS 600 + P P P + AP+T P P P +P L +P A + Sbjct: 579 TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLT--PTTPEKLAPTT 636 Query: 601 PASQLVATPSLELGPIP-------AGEEKALELPLAAS-SIPRPRTPSPESHRSPAEGSE 652 P TP EL P EE A P AA+ + P+ P+ +P E Sbjct: 637 PEKPAPTTPE-ELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE 695 Query: 653 RLSLSPLRGGEAGP--DASPTVTTPTVTTPSLPA-------EVGSPHSTEVDESLSVSFE 703 +P P A T+ P TTP PA P ST D+ + + Sbjct: 696 PAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755 Query: 704 QVLP---------------PSAPTSEAGLSLPLRGPRARRSASPHDV-DLCLVSPCEFEH 747 P P+ P A +L P + +P ++ P Sbjct: 756 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815 Query: 748 RKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAA 807 K P P +P + + + + ++ E PPT+ S PT + +P + Sbjct: 816 DKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPT-TTKEPTTIHKSPD 874 Query: 808 DSDEDTEGFGVPRHDPLPDPLK---VPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRK 864 +S + +P P L+ P +P + PEM + TE RT Sbjct: 875 ESTPELSA------EPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRT-- 926 Query: 865 PLARPNSRAAAPKATPVAAAKTK 887 P + AAPK T A T+ Sbjct: 927 ---TPETTTAAPKMTKETATTTE 946 Score = 48.9 bits (115), Expect = 3e-05 Identities = 107/491 (21%), Positives = 166/491 (33%), Gaps = 81/491 (16%) Query: 470 AESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDP 529 +E++ES S SS + + ++ A E +K + + KK P Sbjct: 161 SENQESSSSSSSSSSSSTI--------RKIKSSKNSAANRELQKKLKVKDNKKNRTKKKP 212 Query: 530 KPSVSRTQPREVRRAASSVPN--LKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLR 587 P +P V A S + N K T + STS PR PSL Sbjct: 213 TP-----KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSL- 264 Query: 588 CGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSP 647 PP++ S V +E +E ++ + T E S Sbjct: 265 -----PPNSDTSKETSLTV------------NKETTVETKETTTTNKQTSTDGKEKTTSA 307 Query: 648 AEGS--ERLS---LSPLRGGEAGPDAS-------PTVTTPTVTTPSLPAEVGSPHSTEVD 695 E E+ S L+P A P P +TTP TP+ P E P ST Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKE---PASTTPK 364 Query: 696 ESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAP 755 E + + SAPT+ P+ + P ++ P P Sbjct: 365 EPTPTTIK-----SAPTT----------PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTP 409 Query: 756 APASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEG 815 +P ++ + A + ++ +E PT+ + PT + +P P P E Sbjct: 410 KEPAPTTTKE-PAPTTTKSAPTTPKEPAPTTPKKPAPT-TPKEPAPTTPKEPTPTTPKEP 467 Query: 816 FGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAA 875 + +P P K P P P P+ P T + E T K + + A Sbjct: 468 APTTK-EPAPTTPKEPAPTA-PKKPAPTTPKEPAPTTPK--EPAPTTTKEPSPTTPKEPA 523 Query: 876 PKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSR 935 P T A TK A P + +S P+ +P + K P T + P+ + + Sbjct: 524 PTTTKSAPTTTKEPA-------PTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKK 575 Query: 936 PGVSATPPKSP 946 P + T PK P Sbjct: 576 P--APTTPKEP 584 Score = 47.4 bits (111), Expect = 7e-05 Identities = 47/195 (24%), Positives = 73/195 (37%), Gaps = 20/195 (10%) Query: 504 KEPARA--EAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPK 561 KEPA + P T + P LK+ + + P+E+ + P ++ A Sbjct: 763 KEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822 Query: 562 PRK-APSTSHSGFP-----PVANGPRSPPSLRCGEASP-----PSAACGSPASQLVATPS 610 P++ AP+T P P P +PP ++P P+ SP +TP Sbjct: 823 PKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDE---STPE 879 Query: 611 LELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASP 670 L P P KALE +P +TP+ ++ + LR A+P Sbjct: 880 LSAEPTP----KALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 935 Query: 671 TVTTPTVTTPSLPAE 685 +T T TT E Sbjct: 936 KMTKETATTTEKTTE 950 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 87.4 bits (215), Expect = 6e-17 Identities = 151/625 (24%), Positives = 219/625 (35%), Gaps = 107/625 (17%) Query: 368 TPLPLSRGPVPAKPTVLFEKMGVGRLDMYVLHPPSAGAERTLASVCALLVWHPAGPGEKV 427 TPLP + P P T L L PPS A +L ++ + PA P Sbjct: 325 TPLPATLPPSPPLATPL------------PLAPPSPSAPPSLQTLPS----PPATP---- 364 Query: 428 VRVLFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEGPG-----------RAESKESV 476 P PP+ + L+ + P+ P L P ++ S+ Sbjct: 365 -----PSQAPPSMTTPPMQAPPSLQTI-PPIQVPHSLTSPSLQAPPSPLALSSLQATTSL 418 Query: 477 GSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRT 536 GS L PR Q + P+R + + P L P S + Sbjct: 419 GSPTLQATHSFLTMSPRQTQ----ASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLS 474 Query: 537 QPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEAS---P 593 + ++ L+ ++ A+ P+ AP +S P +PPSL+ AS P Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQ-APLSSLIMPPLETQSSLAPPSLQTPPASLTTP 533 Query: 594 PSAACGS-------PASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRS 646 P S AS + TP LE P PA L+ P + + P P TPS + Sbjct: 534 PLENLPSLAPPPLQTASAPLTTPHLETPPCPA--PCPLQAPPSPLTTPPPETPSSIA-TP 590 Query: 647 PAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSL--------PAEVGSPH-------S 691 P + L+ PL+G + P SP T P P L P+ SP S Sbjct: 591 PPQAPPALASPPLQGLPS-PPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPS 649 Query: 692 TEVDESLSVSFEQV--LPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRK 749 + +L+V Q PP +P +A S P P + + P L +P + Sbjct: 650 PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP-PLQVPP 708 Query: 750 AVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSES--------LPTLSDSDPVP 801 + P +P P SP ++ A A L +PP S S +P L + P+ Sbjct: 709 SPPASP-PMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ 767 Query: 802 LAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSR 861 + P S +P P + PP L P + P P A + + S Sbjct: 768 VPPSPPAS--------LPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819 Query: 862 TRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTP 921 PLA P P+A PV AA + AS L A P G P Sbjct: 820 PMSPLATP-----PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-----------P 863 Query: 922 KTATRGPSGSASSRPGVSATPPKSP 946 T+ GP + + PG P +SP Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRSP 888 Score = 80.5 bits (197), Expect = 8e-15 Identities = 143/568 (25%), Positives = 205/568 (36%), Gaps = 126/568 (22%) Query: 462 QDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKT 521 +D GP ++ R S+ G PRP AR P E PRK+ A Sbjct: 162 RDTSGPTPGTPSPAMARR--SRAAGTEVGLPRPAPS----ARPRPP-TEGPRKSVSSASE 214 Query: 522 PRELKKDP----KPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAP-STSHSGFPPV 576 + P +PS R R+ SS + A++ P R P + +H P Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK- 273 Query: 577 ANGPRSPPSLRCGEASPP----SAACGSPASQLVATPS---LELGPIPAGEEKALELPLA 629 P+ +LR + +PP + A G +S +ATPS + P+P + A LP Sbjct: 274 ---PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPAT 330 Query: 630 ASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGP--DASPTVTTP------------ 675 P TP P + SP S SL L A P A P++TTP Sbjct: 331 LPPSPPLATPLPLAPPSP---SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387 Query: 676 ------TVTTPSLPA--------------EVGSPHSTEVDESLSVSFEQ----VLPPSAP 711 ++T+PSL A +GSP L++S Q + PS P Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447 Query: 712 TSEAGLSLPLRGPRARRSASPHDVDLC-----LVSPCEFEHRKAVPM--APAPASPGSSN 764 S S PL+ P + ++ P L L SP +A+ + +P +P SS Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL 507 Query: 765 DSSARSQERAGGLGAEETPPTSVS----ESLPTLSDSDPVPLAPGAADSDEDTEGFGVPR 820 + + + +TPP S++ E+LP+L+ P PL +A Sbjct: 508 IMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA---PPPLQTASA------------- 551 Query: 821 HDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATP 880 PL P PP P P P PP T P P+S A P P Sbjct: 552 --PLTTPHLETPPCPAPC------PLQAPPSPL--------TTPPPETPSSIATPPPQAP 595 Query: 881 VAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPS-GSASSRPGVS 939 A A S PL P PLS ++ P A + + P Sbjct: 596 PALA-----------SPPLQGLPSP-------PLSPLATPPPQAPPXLALPPLQAPPSPP 637 Query: 940 ATPPKSPVYLDLAYLPSGSSAHLVDEEF 967 A+PP SP+ P+ + HL+ F Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPF 665 Score = 57.0 bits (136), Expect = 9e-08 Identities = 104/429 (24%), Positives = 139/429 (32%), Gaps = 63/429 (14%) Query: 519 AKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVAN 578 A P P P + +A S P QA P +P S S PP Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPP--PSPPVQAPFSPPASPPVSPSATPP--- 692 Query: 579 GPRSPPSLRCGE--------ASPPSAACGSPASQL---VATPSLELGPIPAGEEKALELP 627 ++PPSL ASPP + +P Q +A P L++ P P P Sbjct: 693 -SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP-----P 746 Query: 628 LAASSIPRPRTP---SPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTT-PSLP 683 ++ S+ P PR P + + P L +SPL + P A P + TP + PS P Sbjct: 747 MSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL--AKPPPQAPPALATPPLQALPSPP 804 Query: 684 AEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPC 743 A SL +S PP AP L P + SP Sbjct: 805 ASFPGQAPFSPSASLPMSPLATPPPQAPPV-------LAAPLLQVPPSP----------- 846 Query: 744 EFEHRKAVPMAPAPASPGSSN-DSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPL 802 A P AP P + D+S L PP S S S TLS D Sbjct: 847 -----PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS-STLSGPDLAGH 900 Query: 803 APGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRT 862 + A + E+ G+ D P+ P PD + + P A Sbjct: 901 SSSATSTPEELRGY-----DSGPEGGAAASPPPD-AELAACHPAAWSRGPAPPLAFRGAP 954 Query: 863 RKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAP----LSRKS 918 PL P + +T+G A L P GG+A S Sbjct: 955 GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS 1014 Query: 919 STPKTATRG 927 +PK A G Sbjct: 1015 RSPKQARLG 1023 Score = 52.8 bits (125), Expect = 2e-06 Identities = 121/505 (23%), Positives = 170/505 (33%), Gaps = 91/505 (18%) Query: 479 RDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQP 538 RD +K T P PG+ P + P TP L+ +P Sbjct: 5 RDKAKAGAAART---PAARAPGLLTPRPPGSPRP----PPPVTPAALRVLGAAGAVGRKP 57 Query: 539 REVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANG--PRSPPSLRC--GEASPP 594 R + ++ +A P S+ + P A+G R+PP+ G S P Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117 Query: 595 SAACGSPASQLVATPSLELGPIPA-GEEKALELPLAAS---------SIPRPRTPSPE-S 643 A G+ + L + KA E P ++ S P P TPSP + Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177 Query: 644 HRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFE 703 RS A G+E P P A P P P S HST + Sbjct: 178 RRSRAAGTEVGLPRP------APSARPR---PPTEGPRKSVSSASEHSTTEPSPAA---- 224 Query: 704 QVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSS 763 P++ GL P A RS S L + P P++ G+ Sbjct: 225 ----RRRPSAGGGLQRP-----ASRSLSSSATPL------------SSPARSGPSARGTP 263 Query: 764 NDSSARSQERAGGLGA----EETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVP 819 + SQ + GL A + TPP ++ P L P+ +P A S T+ VP Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRK--DAAPALG---PLSSSPLATPSPSGTKARPVP 318 Query: 820 RHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKAT 879 PD P P P S + P L P + ++ P A P S+A T Sbjct: 319 P----PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTT 374 Query: 880 PVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSAS------ 933 P A L P S S PS + +PL+ S T+ P+ A+ Sbjct: 375 PPMQA-PPSLQTIPPIQVPHSLTS-PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTM 432 Query: 934 ------------SRPGVSATPPKSP 946 SRP ++TPP SP Sbjct: 433 SPRQTQASLTSPSRP--ASTPPDSP 455 Score = 32.3 bits (72), Expect = 2.4 Identities = 29/89 (32%), Positives = 34/89 (38%), Gaps = 11/89 (12%) Query: 154 ATTPPPVQPPILTI----------TCPTFGDWAQLAPAVPGLQGALRLQLRLNPPAQLPN 203 + TPPP PP L P A P VP L A LQ+ +PPA LP Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM 778 Query: 204 SEGLCEFLEYVAESLEPPSPFELLEPPTS 232 S L + +L P L PP S Sbjct: 779 SP-LAKPPPQAPPALATPPLQALPSPPAS 806 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 83.2 bits (204), Expect = 1e-15 Identities = 133/519 (25%), Positives = 186/519 (35%), Gaps = 71/519 (13%) Query: 460 TPQDLEGPGRAESKESVGSRDSSKREGLLATHPRP-GQERPGVARKEPAR----AEAPRK 514 +P + PGRA T P P GQ+ ++ +E EAP++ Sbjct: 101 SPGPVSSPGRASG----------------TTRPGPLGQKGLRISAEETVARGKATEAPKR 144 Query: 515 TEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKP-----RKAPSTS 569 + A R+ P P RAA + L + A P+P RK+ S++ Sbjct: 145 SALSAGARRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203 Query: 570 --HSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKA---- 623 HS P + R PS G P S + S A+ L ++P+ GP G +A Sbjct: 204 SEHSTTEP-SPAARRRPSAGGGLQRPASRSLSSSATPL-SSPARS-GPSARGTPRAPAHP 260 Query: 624 -LELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSL 682 P ++ P+ P +PA G LS SPL SP+ T PS Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGP--LSSSPLATPSPSAPPSPSAPPSLQTLPSP 318 Query: 683 PAEVGSPHSTEVDESLSVSFEQVLP-----PSA---PTSEAGLSLPLRGPRARRSASPHD 734 PA S +T + + LP P A P + L+LP ASP Sbjct: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378 Query: 735 VDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSAR-SQERAGGLGAEETPPTSVSESLPT 793 L SP + + AV + AP SP S A S + + TPP+ SL Sbjct: 379 SPLATPSP-QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 437 Query: 794 ----LSDSDPV--PLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEM 847 + S P P++P A + P P + PP L P + P Sbjct: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 497 Query: 848 LPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSE 907 P A + + S PLA P P+A PV AA + AS L A P Sbjct: 498 SFPGQAPFSPSASLPMSPLATP-----PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 552 Query: 908 KGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSP 946 G P T+ GP + + PG P +SP Sbjct: 553 PG-----------PDTSVSGPRLTLALAPGPPPPPSRSP 580 Score = 59.7 bits (143), Expect = 1e-08 Identities = 118/510 (23%), Positives = 158/510 (30%), Gaps = 95/510 (18%) Query: 451 LRFLREPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAE 510 L+ LR P VTP R ++ ++G SS + P P + A Sbjct: 268 LQALRPPQVTPP------RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321 Query: 511 APRKTEKEAKTP-----RELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKA 565 P + +P P S T P + A + P QA P P + Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP------LQAPPSPPAS 375 Query: 566 PSTSHSGFP----------------------PVANGPRSPPSLRCGEASPPSAACGSPAS 603 P S P P P SPP ASPP + +P S Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP------ASPPVSPSATPPS 429 Query: 604 QLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGE 663 Q A PSL P+ P++ S+ P P+ P P L+ PL+ + Sbjct: 430 Q--APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP------------LAAPPLQLAK 475 Query: 664 AGPDASPTVTTPTVTT-PSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLR 722 P A P + TP + PS PA SL +S PP AP L Sbjct: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV-------LA 528 Query: 723 GPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSN-DSSARSQERAGGLGAEE 781 P + SP A P AP P + D+S L Sbjct: 529 APLLQVPPSP----------------PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572 Query: 782 TPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSIC 841 PP S S S TLS D + A + E+ G+ D P+ P PD + + Sbjct: 573 PPPPSRSPS-STLSGPDLAGHSSSATSTPEELRGY-----DSGPEGGAAASPPPD-AELA 625 Query: 842 MVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSA 901 P A PL P + +T+G A L Sbjct: 626 ACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP 685 Query: 902 RSEPSEKGGRAP----LSRKSSTPKTATRG 927 P GG+A S +PK A G Sbjct: 686 GPSPGTSGGKAAAGAGAGASSRSPKQARLG 715 Score = 46.2 bits (108), Expect = 2e-04 Identities = 95/412 (23%), Positives = 141/412 (34%), Gaps = 61/412 (14%) Query: 580 PRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPR--PR 637 PR P S R PP +PA+ V + +G P E + ++IP PR Sbjct: 27 PRPPGSPR-----PPPPV--TPAALRVLGAAGAVGRKPLAERAG---GIGGATIPESAPR 76 Query: 638 TPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTP----------SLPAEVG 687 + R PA G + P + GP +SP + T T P S V Sbjct: 77 AGPTRTSRPPASGRGERA-PPAKNTSPGPVSSPGRASGT-TRPGPLGQKGLRISAEETVA 134 Query: 688 SPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSAS----PHDVDLCLVSPC 743 +TE + ++S S PT G P R+R + + P P Sbjct: 135 RGKATEAPKRSALSAGARRDTSGPTP--GTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192 Query: 744 EFEHRKAVPMA-------PAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSD 796 RK+V A P+PA+ + + + L + TP +S + S P+ Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252 Query: 797 SDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDP-SSICMVDPEMLPPKTARQ 855 + P P S +G R + P K P P SS + P P + Sbjct: 253 TPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308 Query: 856 TENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLS 915 ++ P A P S+A +P A L S PLS + P + Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP-----SPPLSPLATPPPQA------ 357 Query: 916 RKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSSAHLVDEEF 967 P P + S P A+PP SP+ P+ + HL+ F Sbjct: 358 -----PPALALPPLQAPPSPP---ASPPLSPLATPSPQAPNALAVHLLQAPF 401 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 82.4 bits (202), Expect = 2e-15 Identities = 144/518 (27%), Positives = 194/518 (37%), Gaps = 81/518 (15%) Query: 460 TPQDLEGPGRAESKESVGSRDSSKREGLLATHPRP-GQERPGVARKEPAR----AEAPRK 514 +P + PGRA T P P GQ+ ++ +E EAP++ Sbjct: 110 SPGPVSSPGRASG----------------TTRPGPLGQKGLRISAEETVARGKATEAPKR 153 Query: 515 TEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKP-----RKAPSTS 569 + A R+ P P RAA + L + A P+P RK+ S++ Sbjct: 154 SALSAGARRDTS-GPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 212 Query: 570 --HSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKA---- 623 HS P + R PS G P S + S A+ L ++P+ GP G +A Sbjct: 213 SEHSTTEP-SPAARRRPSAGGGLQRPASRSLSSSATPL-SSPARS-GPSARGTPRAPAHP 269 Query: 624 -LELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSL 682 P ++ P+ P +PA G LS SPL A P SP+ + P+L Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALGP--LSSSPL----ATP--SPSAALQSQAPPTL 321 Query: 683 PAEVGSPHSTEVDESLSVSFEQVLP-PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVS 741 PA +PHS+ + L+ P PSAP S L P P ++ + S L S Sbjct: 322 PA---TPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS-------LGS 371 Query: 742 PCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSD-SDPV 800 P +P P SP ++ A L A +PP S P LS + P Sbjct: 372 PTLQATHSFLP--SPPLSPLATPPPQAPPALALPPLQAPPSPPAS-----PPLSPLATPS 424 Query: 801 PLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENV- 859 P AP A F P P+ P PP P S P PP A V Sbjct: 425 PQAPNALAVHLLQAPFSPPPSPPVQAPFS--PPASPPVSPSATPPSQAPPSLAAPPLQVP 482 Query: 860 -----SRTRKPLARPNSRAAAP-KATPVAAAKTKGLAGGDRASRPLSA-RSEPSEKGGRA 912 S P A P +A P A P+ AK A A+ PL A S P+ G+A Sbjct: 483 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 542 Query: 913 PLSRKSSTPKTATRGPSGSASSRPGVSATP----PKSP 946 P S +S P + P A P V A P P SP Sbjct: 543 PFSPSASLPMSPLATPPPQA---PPVLAAPLLQVPPSP 577 Score = 81.3 bits (199), Expect = 5e-15 Identities = 127/504 (25%), Positives = 178/504 (35%), Gaps = 65/504 (12%) Query: 462 QDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKT 521 +D GP ++ R S+ G PRP AR P E PRK+ A Sbjct: 162 RDTSGPTPGTPSPAMARR--SRAAGTEVGLPRPAPS----ARPRPP-TEGPRKSVSSASE 214 Query: 522 PRELKKDP----KPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAP-STSHSGFPPV 576 + P +PS R R+ SS + A++ P R P + +H P Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK- 273 Query: 577 ANGPRSPPSLRCGEASPP----SAACGSPASQLVATPSLELGPIPAGEEKALELPLAASS 632 P+ +LR + +PP + A G +S +ATPS P AA Sbjct: 274 ---PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS----------------PSAALQ 314 Query: 633 IPRPRT--PSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPS-LPAEVGSP 689 P T +P S + + L L+P + P + T+ +P T PS +GSP Sbjct: 315 SQAPPTLPATPHSSSLTCQLATPLPLAP--PSPSAPPSLQTLPSPPATPPSQATTSLGSP 372 Query: 690 HSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRK 749 L L P + L+LP ASP L SP + + Sbjct: 373 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP-QAPNAL 431 Query: 750 AVPMAPAPASPGSSNDSSAR-SQERAGGLGAEETPPTSVSESLPT----LSDSDPV--PL 802 AV + AP SP S A S + + TPP+ SL + S P P+ Sbjct: 432 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 491 Query: 803 APGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRT 862 +P A + P P + PP L P + P P A + + S Sbjct: 492 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551 Query: 863 RKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPK 922 PLA P P+A PV AA + AS L A P G P Sbjct: 552 MSPLATP-----PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG-----------PD 595 Query: 923 TATRGPSGSASSRPGVSATPPKSP 946 T+ GP + + PG P +SP Sbjct: 596 TSVSGPRLTLALAPGPPPPPSRSP 619 Score = 58.2 bits (139), Expect = 4e-08 Identities = 91/360 (25%), Positives = 119/360 (33%), Gaps = 57/360 (15%) Query: 574 PPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSI 633 PPV P SPP ASPP + +P SQ A PSL P+ P++ S+ Sbjct: 446 PPV-QAPFSPP------ASPPVSPSATPPSQ--APPSLAAPPLQVPPSPPASPPMSPSAT 496 Query: 634 PRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTT-PSLPAEVGSPHST 692 P P+ P P L+ PL+ + P A P + TP + PS PA Sbjct: 497 PPPQAPPP------------LAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544 Query: 693 EVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVP 752 SL +S PP AP L P + SP A P Sbjct: 545 SPSASLPMSPLATPPPQAPPV-------LAAPLLQVPPSP----------------PASP 581 Query: 753 MAPAPASPGSSN-DSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDE 811 AP P + D+S L PP S S S TLS D + A + E Sbjct: 582 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS-STLSGPDLAGHSSSATSTPE 640 Query: 812 DTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNS 871 + G+ D P+ P PD + + P A PL P + Sbjct: 641 ELRGY-----DSGPEGGAAASPPPD-AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 694 Query: 872 RAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAP----LSRKSSTPKTATRG 927 +T+G A L P GG+A S +PK A G Sbjct: 695 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 754 Score = 50.1 bits (118), Expect = 1e-05 Identities = 119/512 (23%), Positives = 164/512 (32%), Gaps = 99/512 (19%) Query: 479 RDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQP 538 RD +K T P PG+ P + P TP L+ +P Sbjct: 5 RDKAKAGAAART---PAARAPGLLTPRPPGSPRP----PPPVTPAALRVLGAAGAVGRKP 57 Query: 539 REVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANG--PRSPPSLRC--GEASPP 594 R + ++ +A P S+ + P A+G R+PP+ G S P Sbjct: 58 LAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117 Query: 595 SAACGSPASQLVATPSLELGPIPA-GEEKALELPLAAS---------SIPRPRTPSPE-S 643 A G+ + L + KA E P ++ S P P TPSP + Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMA 177 Query: 644 HRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFE 703 RS A G+E P P A P P P S HST + Sbjct: 178 RRSRAAGTEVGLPRP------APSARPR---PPTEGPRKSVSSASEHSTTEPSPAA---- 224 Query: 704 QVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSS 763 P++ GL P A RS S L + P P++ G+ Sbjct: 225 ----RRRPSAGGGLQRP-----ASRSLSSSATPL------------SSPARSGPSARGTP 263 Query: 764 NDSSARSQERAGGLGA----EETPPTSVSESLPTLSDSDPVPLA---PGAADSDEDTEGF 816 + SQ + GL A + TPP ++ P L PLA P AA + Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRK--DAAPALGPLSSSPLATPSPSAALQSQAPPTL 321 Query: 817 -GVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAA 875 P L L P PL PS + LP P A P S+A Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLP--------------SPPATPPSQATT 367 Query: 876 PKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSR 935 +P A L S PLS + P + P P + S Sbjct: 368 SLGSPTLQATHSFLP-----SPPLSPLATPPPQA-----------PPALALPPLQAPPSP 411 Query: 936 PGVSATPPKSPVYLDLAYLPSGSSAHLVDEEF 967 P A+PP SP+ P+ + HL+ F Sbjct: 412 P---ASPPLSPLATPSPQAPNALAVHLLQAPF 440 Score = 43.1 bits (100), Expect = 0.001 Identities = 69/259 (26%), Positives = 95/259 (36%), Gaps = 44/259 (16%) Query: 559 APKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASP---PSAACGSPASQL----VATPSL 611 AP P AP + PP A + P L+ + P P A SP++ L +ATP Sbjct: 501 APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 560 Query: 612 ELGPIPAGEEKALELPLAASSIP------RPRTPSPESHRSPAEGSERLSLSPLRGGEAG 665 + P+ A L++P + + P RP TP P++ S RL+L+ G Sbjct: 561 QAPPVLAA--PLLQVPPSPPASPTLQAPRRPPTPGPDTSVS----GPRLTLALAPGPPPP 614 Query: 666 PDASPTVTTPTVTTPSLPAEVGSPHSTE-----VDESLSVSFEQVLPPSAPTSEAGLSLP 720 P SP + T++ P L S ST D PP A + + Sbjct: 615 PSRSP---SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 671 Query: 721 LRGPR---ARRSA-----------SPHDVD-LCLVSPCEFEHRKAVPMAPAPASPGSSND 765 RGP A R A P D LC + E E ++ AP PG S Sbjct: 672 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI--YETEGPESATPAPGALDPGPSPG 729 Query: 766 SSARSQERAGGLGAEETPP 784 +S G GA P Sbjct: 730 TSGGKAAAGAGAGASSRSP 748 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 76.3 bits (186), Expect = 1e-13 Identities = 121/466 (25%), Positives = 162/466 (34%), Gaps = 67/466 (14%) Query: 494 PGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKK 553 P +E P E +R P + + P E P P VSR P V S P Sbjct: 611 PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESP 670 Query: 554 TNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLEL 613 + P P + PP + P SPP ASPP P L++ P E Sbjct: 671 LSPPPEESPTSPPPEASRLSPPPEDSPTSPPP-EDSPASPP------PEDSLMSLPLEES 723 Query: 614 GPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVT 673 +P EE L P + PR P H SP E LSP P SP Sbjct: 724 PLLPLPEEPQL-CPRSEGPHLSPRPEEP--HLSPR--PEEPHLSP---QAEEPHLSPQPE 775 Query: 674 TPTVTT----PSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRS 729 P + P L + PH + E L +S + P +P E P P+ S Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEE----PCLSPQPEES 831 Query: 730 -ASPHDVDLCLVSPCEFEH----RKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPP 784 SP + CL E H + P++P P P E G A E P Sbjct: 832 HLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP----------PEEPGQCPAPEELP 881 Query: 785 TSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVD 844 P+LS PL A S+ G P PLP+ L + P S ++ Sbjct: 882 LFPPPGEPSLS-----PLLGEPALSEP-----GEPPLSPLPEELPLSPSGEPSLSPQLMP 931 Query: 845 PEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSE 904 P+ LPP PL+ + AA P +P+ + A GD S P S + Sbjct: 932 PDPLPP--------------PLSPIITAAAPPALSPLGELEYPFGAKGD--SDPESPLAA 975 Query: 905 PSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLD 950 P + +P + T P PG S P SP+ ++ Sbjct: 976 PILETPISPPPEANCTDPEPV--PPMILPPSPG-SPVGPASPILME 1018 Score = 69.3 bits (168), Expect = 2e-11 Identities = 86/328 (26%), Positives = 114/328 (34%), Gaps = 28/328 (8%) Query: 533 VSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEAS 592 V+ QP+E L K Q P+ + PP P SPP + Sbjct: 401 VTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSP 460 Query: 593 PPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSE 652 PP A+ SP P EL P E L PL S + P SP S + Sbjct: 461 PPEASRLSP-------PPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFS 513 Query: 653 RLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPT 712 L SPL + P+ SP +P + TP P SP S +ES + LP S P Sbjct: 514 PLEESPL----SPPEESP--PSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP 567 Query: 713 SEAGLS-----LPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAP-ASPGSSNDS 766 + LS P+ P SP L P E P++P P SP S Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFE-----ESPLSPPPEESPLSPPPE 622 Query: 767 SARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPD 826 ++R P S P +S P+P+ + E++ P P Sbjct: 623 ASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSP 682 Query: 827 PLKV----PPPLPDPSSICMVDPEMLPP 850 P + PPP P+S D PP Sbjct: 683 PPEASRLSPPPEDSPTSPPPEDSPASPP 710 Score = 68.9 bits (167), Expect = 2e-11 Identities = 119/483 (24%), Positives = 169/483 (34%), Gaps = 61/483 (12%) Query: 522 PRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPR 581 P E P P SR P AS +P + P P PP + P Sbjct: 453 PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPF 512 Query: 582 SPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSP 641 SP L SPP + SPA + +P E P+ E E PL+ P +P P Sbjct: 513 SP--LEESPLSPPEESPPSPALETPLSPPPEASPLSPPFE---ESPLSPPPEELPTSPPP 567 Query: 642 ESHR-SPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSV 700 E+ R SP +S P + P + + P +P P SP S + S Sbjct: 568 EASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLS 627 Query: 701 SFEQVLPPSAPTSEAGLSLPLRGPR-------ARRSASPHDVDL------CLVSPCEFEH 747 + P S P E+ +S P R +R S P + L SP Sbjct: 628 PPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEAS 687 Query: 748 RKAVPMAPAPAS-PGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGA 806 R + P +P S P + +S ++ L EE+P LP + P + G Sbjct: 688 RLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESP------LLPLPEEPQLCPRSEGP 741 Query: 807 ADSDEDTEGFGVPR-HDPLPDPLKVPP---PLPDPSSICMV--DPEMLP----PKTARQT 856 S E PR +P P P P P+ +C V +P + P P + Q Sbjct: 742 HLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQP 801 Query: 857 ENV---SRTRKPLARP------------NSRAAAPKATPVAAAK-TKGLAGGDRASRPLS 900 E + +T +P P S + P + + + + PLS Sbjct: 802 EELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLS 861 Query: 901 ARSE-PSEKGGRAPLSRK---SSTPKTATRGP--SGSASSRPGVSATPPKSPVYLDLAYL 954 R E P E+ G+ P + P + P A S PG PP SP+ +L Sbjct: 862 PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPG---EPPLSPLPEELPLS 918 Query: 955 PSG 957 PSG Sbjct: 919 PSG 921 Score = 57.4 bits (137), Expect = 7e-08 Identities = 123/510 (24%), Positives = 171/510 (33%), Gaps = 117/510 (22%) Query: 456 EPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKT 515 EP ++PQ E +S+E S + +H P E+P ++ R E P + Sbjct: 821 EPCLSPQPEESHLSPQSEEPCLSPRPEE------SHLSPELEKPPLS----PRPEKPPEE 870 Query: 516 EKEAKTPRELKKDPKPSVSRTQPREVRRAASSV--PNLKKTNAQAAPKPRKAPSTSHSGF 573 + P EL P P P A S P L + P PS S Sbjct: 871 PGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLM 930 Query: 574 PPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELG-PIPAGEEKALELPLAASS 632 PP P PP SP A PA +P EL P A + E PLAA Sbjct: 931 PP---DPLPPP------LSPIITAAAPPA----LSPLGELEYPFGAKGDSDPESPLAAPI 977 Query: 633 IPRPRTPSPESHRS-----------PAEGSERLSLSPLRGGEAGPDASPTVTTPTV---- 677 + P +P PE++ + P+ GS SP+ P SP + V Sbjct: 978 LETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNS 1037 Query: 678 -----TTPSLPAEVGSPHS--------TEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGP 724 + P+LP V SP S ++ E + E+V P P E + PL P Sbjct: 1038 PPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSP 1097 Query: 725 RARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPP 784 DL +P +PAPA S GLG + P Sbjct: 1098 MG---------DLSCPAP-----------SPAPALDDFS------------GLGEDTAPL 1125 Query: 785 TSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVD 844 + APG+ T G L LK P L DP + V Sbjct: 1126 DGID--------------APGSQPEPGQTPG-------SLASELKGSPVLLDPEELAPVT 1164 Query: 845 PEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAA---AKTKGLAGGDRA-----S 896 P + P+ +QT + P + A T + + + L+ GD + S Sbjct: 1165 PMEVYPE-CKQTAGQGSPCEEQEEPRAPVAPTPPTLIKSDIVNEISNLSQGDASASFPGS 1223 Query: 897 RPLSARSEPSEKGGRAPLSRKSSTPKTATR 926 PL +P E GG + ST + R Sbjct: 1224 EPLLGSPDP-EGGGSLSMELGVSTDVSPAR 1252 Score = 54.7 bits (130), Expect = 5e-07 Identities = 122/545 (22%), Positives = 187/545 (34%), Gaps = 82/545 (15%) Query: 457 PVVTPQDLEGPGRAESKESVGSRDSSKREGLLAT----------HPRPGQERPGVARKEP 506 P + EG G + ++ S+ + + G L+T P Q+ P + + Sbjct: 1984 PTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCK 2043 Query: 507 ARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAP 566 + RK K P K + R +V++ A S N K+T + P Sbjct: 2044 QIMKLWRKVPAADKAPYLQKAKDNRAAHRIN--KVQKQAESQIN-KQTKVGDIARKTDRP 2100 Query: 567 STSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALE- 625 + H PP SPP A+ P+ GSP + PAG + + Sbjct: 2101 AL-HLRIPPQPGALGSPPP-----AAAPTIFIGSPTT-------------PAGLSTSADG 2141 Query: 626 -LPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPA 684 L A S+P P +P + P + ++ G P T T P P+ Sbjct: 2142 FLKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPS 2201 Query: 685 EVGSPHSTEVDESLSVSFE------QVLPPSAPTSEAGLSLPLRGPRAR---RSASPHDV 735 G+P + + S PP P + P PR A P Sbjct: 2202 PTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESP 2261 Query: 736 DLC-------LVSPCEF-EHRKAVPM--------APAPASPGSSNDSSARSQERAGGLGA 779 + L+SP F E RKA+ + +P+ P S S GGL Sbjct: 2262 GVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLEL 2321 Query: 780 EETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSS 839 + TP D PL P A+ + + G G+ +P P P P P Sbjct: 2322 K-TP------------DVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI 2368 Query: 840 I---CMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRAS 896 DP PP T R + L P S + P + A+ +++ + Sbjct: 2369 FRPGSYTDPYAQPPLTPRPQPPPPESCCALP-PRSLPSDPFSRVPASPQSQSSSQSPLTP 2427 Query: 897 RPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPS 956 RPLSA E +P++ + +P +R PS S P P P ++A+ + Sbjct: 2428 RPLSA-----EAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAF-KA 2481 Query: 957 GSSAH 961 GS AH Sbjct: 2482 GSLAH 2486 Score = 52.8 bits (125), Expect = 2e-06 Identities = 119/522 (22%), Positives = 180/522 (34%), Gaps = 83/522 (15%) Query: 456 EPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKT 515 EP+++P P ES++++ K+E L A+ P G G + + Sbjct: 2270 EPLLSP-----PPFGESRKAL----EVKKEELGASSPSYGPPNLGFV---DSPSSGTHLG 2317 Query: 516 EKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQA-APKPRKAPSTSHSGF- 573 E KTP K P S+ +P+ + + AQA AP P P G Sbjct: 2318 GLELKTPDVFKAPLTPRASQVEPQS---PGLGLRPQEPPPAQALAPSPPSHPDIFRPGSY 2374 Query: 574 ------PPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLE------LGPIPAGEE 621 PP+ P+ PP C A PP + P S++ A+P + L P P E Sbjct: 2375 TDPYAQPPLTPRPQPPPPESCC-ALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAE 2433 Query: 622 KALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPS 681 P+ PR ++P P S R P+ R +PL P P Sbjct: 2434 AFCPSPVT----PRFQSPDPYS-RPPSRPQSRDPFAPLH------------KPPRPQPPE 2476 Query: 682 LPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVS 741 + + GS T SL P+ P E +P P + + S Sbjct: 2477 VAFKAGSLAHT----SLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPS 2532 Query: 742 PCEFEHRKAV------PMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLS 795 P F +AV P P P P +S G G P S + ++ T + Sbjct: 2533 PMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHF------GPGPTLGKPQSTNYTVATGN 2586 Query: 796 -DSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLP--PKT 852 PL P + + E +G+ PL P +PPP PD S LP Sbjct: 2587 FHPSGSPLGPSSGSTGES---YGL---SPLRPPSVLPPPAPDGS---------LPYLSHG 2631 Query: 853 ARQTENVSRTRKPLARPNSRAAAPKAT-PVAAAKTKGLAGGDRAS-RPLSARSEPSEKGG 910 A Q ++ + P + + AT + + G++G + R E Sbjct: 2632 ASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLI 2691 Query: 911 RAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLA 952 R + R + + T + A PG P SP + L+ Sbjct: 2692 RQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLS 2733 Score = 35.8 bits (81), Expect = 0.22 Identities = 90/378 (23%), Positives = 121/378 (32%), Gaps = 77/378 (20%) Query: 521 TPRELKKD---PKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPR--------KAPSTS 569 TPR L + P P R Q + S P + A PR KA S + Sbjct: 2426 TPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLA 2485 Query: 570 HS-----GFPP-VANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIP-AGEEK 622 H+ GFP + GP + PP+ V TPS P A E Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP 2545 Query: 623 ALELPLAASSIPRPRT------PSPE--------------------SHRSPAEGS--ERL 654 +L+ P+ +P P P P S P+ GS E Sbjct: 2546 SLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESY 2605 Query: 655 SLSPLRGGEAGPDASPTVTTPTVTTPSL-------PAEVGSPHSTEVDESLSVSFEQVLP 707 LSPLR P +P + P ++ + P E T + SL+ + LP Sbjct: 2606 GLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATA---ELP 2662 Query: 708 PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPA-----PASPGS 762 + +GLS + +R + + K A A P S G+ Sbjct: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGA 2722 Query: 763 SNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHD 822 S A Q G T S LP S P+ L PG+ SD Sbjct: 2723 EPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPI-LGPGSFPSD------------ 2769 Query: 823 PLPDPLKVPPPLPDPSSI 840 D L PPP PSS+ Sbjct: 2770 ---DRLSRPPPPATPSSM 2784 >gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical region 1 [Homo sapiens] Length = 1400 Score = 69.7 bits (169), Expect = 1e-11 Identities = 112/503 (22%), Positives = 176/503 (34%), Gaps = 54/503 (10%) Query: 455 REPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRK 514 + V D G +S ++ +S + + H + + P + A K Sbjct: 237 KSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASK 296 Query: 515 TE-KEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGF 573 T K TP E +K SRT + + N+++T + A T H G Sbjct: 297 TTYKTTGTPEESEKTED---SRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGR 353 Query: 574 PPVANG---PRSPPSLRCGEASPPSAAC-GSPASQLVATPSLELGPIPAGEEKALELPLA 629 N P P R A+ + P T + P PAG + E+ Sbjct: 354 TANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTAN 413 Query: 630 ASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSP 689 ++ P P+ R+ E + P GE T TTPS PAE Sbjct: 414 ENTTLFPAEPTEHGERTANENTTPSPAEPTEHGER--------TANENTTPS-PAE---- 460 Query: 690 HSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRK 749 TE E + ++ SA ++E G PL A + +P + P E R Sbjct: 461 -PTEHGERTPFANDKTTSSSAESTEHGERTPL----ANENTTPSPAE-----PTENRERT 510 Query: 750 AVP-MAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAAD 808 A P+PA P + +++A + + E T+ +E T S ++P Sbjct: 511 ANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKT-TPSPAEPTENGQRTPF 569 Query: 809 SDEDTEGFGVP-----RHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTR 863 ++E T PL + P P + E P A TEN RT Sbjct: 570 ANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRT- 628 Query: 864 KPLARPNSRAAAPKATPVAAAKTKGLAGGDRA----SRPLSARSEPSEKGGRAPLSRKSS 919 PLA K TP A T+ G R + S+ +EP+E R PL+ +++ Sbjct: 629 -PLANE-------KTTPSLAEPTEN---GQRTPFANEKTTSSSAEPTEHEERTPLANENT 677 Query: 920 TPKTATRGPSGSASSRPGVSATP 942 TP A + ++ + +P Sbjct: 678 TPSPAEPTENRERTANENTTPSP 700 Score = 65.9 bits (159), Expect = 2e-10 Identities = 111/491 (22%), Positives = 175/491 (35%), Gaps = 75/491 (15%) Query: 468 GRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKK 527 G E++E + +++ L P ER P+ AE TE +T E Sbjct: 403 GPTENREMTANENTT----LFPAEPTEHGERTANENTTPSPAEP---TEHGERTANE-NT 454 Query: 528 DPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVAN-----GPRS 582 P P+ +P E + N K T++ A ST H P+AN P Sbjct: 455 TPSPA----EPTE-HGERTPFANDKTTSSSAE-------STEHGERTPLANENTTPSPAE 502 Query: 583 PPSLR---CGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTP 639 P R E + PS A + + A L P+ E + E + P P P Sbjct: 503 PTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENR--ETTANEKTTPSPAEP 560 Query: 640 SPESHRSPAEGSERLSLS--PLRGGEAGP----DASPTVTTPTV---------TTPSLPA 684 + R+P + S S P GE P + +P+ PT TTPS PA Sbjct: 561 TENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPS-PA 619 Query: 685 EVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCE 744 E TE + ++ E+ P A +E G P + S++ Sbjct: 620 E-----PTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPT---------- 664 Query: 745 FEHRKAVPMA-----PAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDP 799 EH + P+A P+PA P + + +A G E + +E TL ++P Sbjct: 665 -EHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKT-TLFPAEP 722 Query: 800 VPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENV 859 A+ ++ T P + P + ++ +P +T EN Sbjct: 723 TENRERTAN-EKTTSSPAEPTENGQRTPFA-----NEKTTSSSAEPTEHGERTPLANENT 776 Query: 860 SRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSS 919 + + R A K TP A T+ + S ++P+E G R PL+ + + Sbjct: 777 TLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSP-AQPTENGDRTPLANEKT 835 Query: 920 TPKTATRGPSG 930 TP A +G Sbjct: 836 TPSLAEPTENG 846 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 69.7 bits (169), Expect = 1e-11 Identities = 108/418 (25%), Positives = 160/418 (38%), Gaps = 69/418 (16%) Query: 544 AASSVPNLKKTNAQAAP-KPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPA 602 AA+ VP N R+AP + PP+A PR P S G PA Sbjct: 1294 AANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSS-------------GLPA 1340 Query: 603 SQLVATPSLELGPIPAGEEKALELPLAASSIPRP-----RTPSPESHRSPAEGSERLSLS 657 L P+L G +P P+ ++ RP +PSPE S A G+ L++S Sbjct: 1341 V-LNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS-APGAAPLTIS 1398 Query: 658 -PLRGGEA--GPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPT-- 712 PL + GP +SP +P SP ++ V ++SV LP S PT Sbjct: 1399 SPLHVPSSLPGPASSP-----------MPIPNSSPLASPVSSTVSVPLSSSLPISVPTTL 1447 Query: 713 ---SEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSAR 769 + A L++P+ P ++ P L V+P P+ PA P S S A Sbjct: 1448 PAPASAPLTIPISAPLTVSASGP--ALLTSVTP------PLAPVVPAAPGPPSLAPSGAS 1499 Query: 770 SQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLK 829 A LG P S S+ + P+ LAP + P P+ P Sbjct: 1500 PSASALTLGLATAPSLSSSQ-----TPGHPLLLAP-TSSHVPGLNSTVAPACSPVLVPAS 1553 Query: 830 -VPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKG 888 + P P + +L P ++ ++ ++ P+A P + AP P A Sbjct: 1554 ALASPFPSAPNPAPAQASLLAPASS-ASQALATPLAPMAAPQTAILAPSPAP-PLAPLPV 1611 Query: 889 LAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSP 946 LA A+ L++ P P+ SSTP T+ AS+ P + TP +P Sbjct: 1612 LAPSPGAAPVLASSQTP------VPVMAPSSTPGTSL------ASASPVPAPTPVLAP 1657 Score = 67.8 bits (164), Expect = 5e-11 Identities = 112/433 (25%), Positives = 158/433 (36%), Gaps = 71/433 (16%) Query: 558 AAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACG-SPASQLVATPSLE---- 612 AAP P PS + SG P A+ +L G A+ PS + +P L+ P+ Sbjct: 1486 AAPGP---PSLAPSGASPSAS------ALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPG 1536 Query: 613 LGPIPAGEEKALELPLAASSIPRPRTPSPE----SHRSPAEGSERLSLSPLRGGEAGPDA 668 L A + +P +A + P P P+P S +PA + + +PL A P Sbjct: 1537 LNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPL-APMAAPQT 1595 Query: 669 SPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSL--------- 719 + +P LP SP + V S + +P AP+S G SL Sbjct: 1596 AILAPSPAPPLAPLPVLAPSPGAAPV----LASSQTPVPVMAPSSTPGTSLASASPVPAP 1651 Query: 720 -PLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLG 778 P+ P + ++ P V L SP + P A AP GSS SQ + G G Sbjct: 1652 TPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAP-ALAPTLGGSSP-----SQTLSLGTG 1705 Query: 779 AEETPPTSVSESLPTLSDSDPVP-----LAPGAADSDEDTEGFGVPRHDPLPDPLKVPPP 833 + P + + SL S P P LAPG T P P P Sbjct: 1706 NPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLA-----PAPPLAPASPV 1760 Query: 834 LPDPSSICMVDP-----EMLPPKTARQTENVSRTRKPLARP---NSRAAAPKATPVAAAK 885 P P+ + P +L P + QT +S P P + A AP +T A++ Sbjct: 1761 GPAPAHTLTLAPASSSASLLAPASV-QTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQ 1819 Query: 886 TKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSAT---- 941 L + PL P R P+S+ T GP S+ Sbjct: 1820 ASSLVVSASGAAPL-----PVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPRPRR 1874 Query: 942 ----PPKSPVYLD 950 PP+SP YLD Sbjct: 1875 QPPPPPRSPFYLD 1887 Score = 56.6 bits (135), Expect = 1e-07 Identities = 90/353 (25%), Positives = 121/353 (34%), Gaps = 48/353 (13%) Query: 499 PGVARKEPARAE--APRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNA 556 P PA+A AP + +A P P+ A S P L Sbjct: 1560 PSAPNPAPAQASLLAPASSASQALAT--------PLAPMAAPQTAILAPSPAPPLAPLPV 1611 Query: 557 QAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACG--SPASQLVATPSLELG 614 AP P AP + S P P S P ASP A +P+S P+ Sbjct: 1612 -LAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPS 1670 Query: 615 PIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEG-------SERLSLSPLRGGEAGPD 667 P+P+ L LA + P SP S G ++ LSL+P Sbjct: 1671 PLPS-PASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTP--------- 1720 Query: 668 ASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRAR 727 AS V TP T P P T LS++ L P++P A P + Sbjct: 1721 ASSLVPTPAQTLSLAPGPPLGPTQT-----LSLAPAPPLAPASPVGPAPAHTLTLAPASS 1775 Query: 728 RSA--SPHDVDLCLVSPC---EFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEET 782 ++ +P V +SP A +A APAS + + +S S GA Sbjct: 1776 SASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAS--TQSPASQASSLVVSASGAAPL 1833 Query: 783 PPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLP 835 P T VS + + D + L G FG PR P + PPP P Sbjct: 1834 PVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGGPR------PRRQPPPPP 1880 Score = 53.9 bits (128), Expect = 8e-07 Identities = 108/472 (22%), Positives = 161/472 (34%), Gaps = 94/472 (19%) Query: 497 ERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNA 556 E P AR P R E + + P P V R P + +++ Sbjct: 2712 EGPSPAR--PPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQ 2769 Query: 557 QAAPKPRKAPSTSHSGFPPVA------NGPRSPPSLR--CGEASPPSAACGSPASQLVAT 608 Q P S + P + +GP S P + C EA+P S+ P +A Sbjct: 2770 QRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPC-EAAPSSSLPTPPQQPFIAR 2828 Query: 609 PSLELGPIPAGEEK---ALELPLAASSIPRPRTPSPESHRSPAE---GSERLSLSPLRGG 662 +ELG G + L + ++ R R P+ +RSPA+ G + S L+G Sbjct: 2829 RHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGK 2888 Query: 663 EAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLR 722 G D P T V P L Q++P P Sbjct: 2889 TNGADPVPGPETLIVADPVLE-------------------PQLIPGPQPL---------- 2919 Query: 723 GPRARRSASPHDVDLCLVSPCEFEHRKAVPMA---PAPASPGSSNDSSARSQERAGGLGA 779 GP+ +P L+SP E R P A P P + S+ D ++ S+ Sbjct: 2920 GPQPVHRPNP------LLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESR-------T 2966 Query: 780 EETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSS 839 + P S LP L P A A T P+ P PP P PS Sbjct: 2967 QPPPHPSPLTPLPPLL---VCPTATVANTVTTVTISTSPPKRKRGRPPKN--PPSPRPSQ 3021 Query: 840 ICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPL 899 + ++D + + ++ + R R+P + +++G + + SRPL Sbjct: 3022 LPVLDRD---STSVLESCGLGRRRQPQGQ---------------GESEGSSSDEDGSRPL 3063 Query: 900 S--ARSEPSEKGGRAPLSRKSSTPKT-------ATRGPSGSASSRPGVSATP 942 + AR +G R S S A GP G + P VS TP Sbjct: 3064 TRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTP 3115 Score = 52.8 bits (125), Expect = 2e-06 Identities = 123/522 (23%), Positives = 182/522 (34%), Gaps = 116/522 (22%) Query: 462 QDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKT 521 ++ EGPG A + S G+ + R A P ERPG E R A +T+ T Sbjct: 2359 EEEEGPG-AGDESSCGTGGGTHRRSKKAKAP----ERPGTRVSERLRG-ARAETQGANHT 2412 Query: 522 PRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPR 581 P + S T P A VP + AP+PR P+++ + P + P Sbjct: 2413 PVISAHQTR---STTTPPRCSPARERVP-------RPAPRPRPTPASAPAAIPALVPVPV 2462 Query: 582 SPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSP 641 S P +P++A P P T P Sbjct: 2463 SAP-----------------------------------------VPISA---PNPITILP 2478 Query: 642 ESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVS 701 H P SP + P +SP T P TP PA P T + ++ S Sbjct: 2479 -VHILP---------SPPPPSQIPPCSSPACTPPPACTPP-PAHTPPPAQTCL---VTPS 2524 Query: 702 FEQVL-PPSAPTSEAGLSLPLRGPR------ARRSASPHDVDLCLVSPCEFEHRKAVP-- 752 +L PPS P S + +LPL G R A+ ASP ++L V+ E VP Sbjct: 2525 SPLLLGPPSVPISASVTNLPL-GLRPEAELCAQALASPESLELASVASSETSSLSLVPPK 2583 Query: 753 ----------------MAPAPASPGSSNDSSA--RSQERAGGLGAEETPPTSV--SESLP 792 ++ P++P + ++ + QE+ AE T T + E LP Sbjct: 2584 DLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELP 2643 Query: 793 -TLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPK 851 +S+S+ + L P AA + E R K P P+ +V E+ P Sbjct: 2644 LCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQE-LVTAEVAAPS 2702 Query: 852 TARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSAR----SEPSE 907 T+ + P P R +A G G + R L R E E Sbjct: 2703 TSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKE 2762 Query: 908 KGGRAPLSRKSST------PKTATRGPSGSASSRPGVSATPP 943 R R +++ +T+ S S S G ++PP Sbjct: 2763 LVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPP 2804 Score = 42.4 bits (98), Expect = 0.002 Identities = 124/549 (22%), Positives = 186/549 (33%), Gaps = 115/549 (20%) Query: 492 PRPGQERPGVAR------KEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAA 545 PRP + V R K+ R + P ++ P P +S QP Sbjct: 985 PRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELS-AQP-----TP 1038 Query: 546 SSVPNLKKTNAQAAPKPRKAPSTSHSGFP-PVANGPRSPPSLRCGEASPPSAACGSPASQ 604 VP + + + P P S P PV P P S + P S S+ Sbjct: 1039 GPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSR 1098 Query: 605 LVATPSLELGPIPAGEEKALEL-PLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGE 663 TP+L L P P + P +SS+ +P T P PA + Sbjct: 1099 -PPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAAT------------ 1145 Query: 664 AGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLS--------VSFEQVLP-PSAPTSE 714 + + TT T TT ++PA +P + + VS Q+ P + Sbjct: 1146 -----TTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVAN 1200 Query: 715 AGLSLP-----------LRGPRARRSA--SPHDVDLCLV-------------SPCEFEHR 748 AG S P L G + R+ A P + +V P Sbjct: 1201 AGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALI 1260 Query: 749 KAVPMAPAPAS----PGSSNDSSARSQERAGGLGAEETPPTSVSES---------LPTLS 795 +AV P P P S+ ++ + L A + PPT V+ + P Sbjct: 1261 QAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDG 1320 Query: 796 DSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVP------PPLPDPSSICMV------ 843 + PLAP PR P L P P+P P+ + + Sbjct: 1321 LTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHS 1380 Query: 844 -DPEM------LPPKTARQTENVSRT-----RKPLARPNSRAAAPKATPVAAAKTKGLAG 891 PE+ P T +V + P+ PNS +P A+PV++ + L+ Sbjct: 1381 PSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNS---SPLASPVSSTVSVPLSS 1437 Query: 892 GDRASRPLSARSEPSEKGGRAPLSRKSSTPKT-ATRGPSGSASSRPGVSATPPKSPVYLD 950 S P + + S APL+ S P T + GP+ S P ++ P +P Sbjct: 1438 SLPISVPTTLPAPAS-----APLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPS 1492 Query: 951 LAYLPSGSS 959 LA PSG+S Sbjct: 1493 LA--PSGAS 1499 >gi|31324577 molecule interacting with Rab13 [Homo sapiens] Length = 863 Score = 68.9 bits (167), Expect = 2e-11 Identities = 113/447 (25%), Positives = 164/447 (36%), Gaps = 52/447 (11%) Query: 449 QHLRFLREPVVTPQDLEGPGRAESK----ESVGSRDSSKREGLLATHPR-PGQERPGVAR 503 QH + L E +D+ G G + S E+ G + S + + T PR PG+ + + Sbjct: 240 QHQQQLAEDA---KDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASP 296 Query: 504 KEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPR 563 APRK E+ TP P+P S Q V +A SS + + PKPR Sbjct: 297 PAGRPTPAPRKAS-ESTTPAP--PTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPR 353 Query: 564 KAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKA 623 P S P + PP + +A P P S PS + + G + Sbjct: 354 GTPKPSEGTPAP----RKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEE 409 Query: 624 LELPLAASSI-PRPRTP---SPESHRSPAEGSERLSLSPLRG-GEAGPDA-------SPT 671 + P +S+ +P P E A + L+ SP G E+ P + +PT Sbjct: 410 VAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPT 469 Query: 672 VTTPTVTTPSLPAEVGSP---HSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARR 728 + T P+ A SP H++ + S PPSA S A L A + Sbjct: 470 SSPKTKKRPAPRAPSASPLALHASRLSHS--------EPPSATPSPALSVESLSSESASQ 521 Query: 729 SASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGS----SNDSSARSQERAGGLGAEETPP 784 +A L+ P + P AP +PG+ S +SS S E+ P Sbjct: 522 TAGAE-----LLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQ 576 Query: 785 TSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVD 844 S + T S P P P T V P+P P P L SS C + Sbjct: 577 ASPGLAPRTRGSSGPQPAKP--CSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSS-CKEN 633 Query: 845 PEMLPPKTARQ--TENVSRTRKPLARP 869 P P A T+ ++ KP+ P Sbjct: 634 PFNRKPSPAASPATKKATKGSKPVRPP 660 Score = 48.5 bits (114), Expect = 3e-05 Identities = 96/433 (22%), Positives = 135/433 (31%), Gaps = 63/433 (14%) Query: 554 TNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSL-- 611 T + P P P H +A + P ++P A P + A P + Sbjct: 225 TRSGTRPGPFSQPKQQHQ--QQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPT 282 Query: 612 ---------ELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGG 662 EL PAG + S+ P P TP P S E+ S L G Sbjct: 283 KPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNG 342 Query: 663 EAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSA---PTSEAGLSL 719 P + PA P + ++ LPPS+ P S+ + Sbjct: 343 RLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQV 402 Query: 720 PLRGPRARRSASP-HDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLG 778 G SP ++ +P E E APA S +S LG Sbjct: 403 ENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATS-----------PALG 451 Query: 779 AEETPPTSVSE---SLPTLSDSD---PVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPP 832 E+ P S+ PT S P P AP A+ + H + P Sbjct: 452 HPESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASP---------LALHASRLSHSEPPS 502 Query: 833 PLPDPSSICMVDPEMLPPKTARQTENVSRTRKPL-----ARPNSRAAAPKATPVAAAKTK 887 P P+ + E L ++A QT P + P A PV+ + Sbjct: 503 ATPSPA----LSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNS 558 Query: 888 GLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPV 947 LA P P G AP TRG SG ++P ATP + Sbjct: 559 SLASSGELVEP-RVEQMPQASPGLAP----------RTRGSSGPQPAKPCSGATPTPLLL 607 Query: 948 YLDLAYLPSGSSA 960 D + +PS S+ Sbjct: 608 VGDRSPVPSPGSS 620 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 68.6 bits (166), Expect = 3e-11 Identities = 137/584 (23%), Positives = 212/584 (36%), Gaps = 103/584 (17%) Query: 433 PGCTPPACLLDGLVR--LQHLRFLREPVVTPQDLE------GPGRAESKESVGSRDSSKR 484 PG P GL + Q ++ PV P + GP + ++++ + SS++ Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385 Query: 485 EGLLATHPRPGQERPGVARKEPARAEAPRKTE-KEAKTPRELKKDP-------KPSVSRT 536 G P+ + PGV K PA+ P K ++ TP+ L + P P ++T Sbjct: 386 PG-----PKALAQPPGVG-KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439 Query: 537 ---QPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASP 593 QP + A K + Q P + + PP GP PP + G A P Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499 Query: 594 PSAACGSPASQLVATPSLELGPI-PAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSE 652 PS GS P + GP P+ ++ P S P PS + SPA+ S Sbjct: 500 PSQQPGS-----TKPPPQQPGPAKPSPQQPGSTKP--PSQQPGSAKPSAQ-QPSPAKPSA 551 Query: 653 RLSLSPLRGGEAGPDASPTVTTPTVTTP---SLPAEVGSPHSTEVDESLSVSFEQVLPPS 709 + S P+ +G P +P+ P LP + P + L V + Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI-CPLCNTTELLLHVPEKANFNTC 610 Query: 710 APTSEAGLSLPLRGPRARRSASPH--DVDLCLVSPCEFEHRKAVPMAPAPASP------- 760 SL P +PH +V L C+ + +AP P+SP Sbjct: 611 TECQTTVCSLCGFNP------NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA 664 Query: 761 -----GSSNDSSARSQERAGGLGA-----------EETPPTSVSESLPTL---------- 794 + + SS + Q+ + A + PP V + PTL Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ--PTLHGSPSAKAKQ 722 Query: 795 -----SDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPD--PSSICMVDPEM 847 S S P P + S++D P D P K+ P D SS P++ Sbjct: 723 PPEADSLSKPAPPKEPSVPSEQDK----APVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778 Query: 848 LPPKTARQTENVSRTRKPL----ARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARS 903 P + Q++ +T PL A+P S++ P V+ +K + S+ +S Sbjct: 779 --PSSKVQSQAEEKTTPPLKTDSAKP-SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835 Query: 904 EPSEKGGRA---PLSRKSSTPKTATR-GPSGSASSRPGVSATPP 943 SE G+ P+ +K K T+ P A P S TPP Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879 Score = 62.4 bits (150), Expect = 2e-09 Identities = 118/566 (20%), Positives = 194/566 (34%), Gaps = 85/566 (15%) Query: 457 PVVTPQDLEGPGRAESKESVGSRDSSKREG------LLATHPRPGQERPGVARKEPARAE 510 P TP GPG+ ++++ + S+++ G L +P ++PG A+ P + Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG 495 Query: 511 APRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSH 570 + + ++ + + + P P+ Q + S P K +AQ P P K PS Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ-PSPAK-PSAQQ 553 Query: 571 SGFPPVANG---PRSPPSLRCGEASPPSAACGSPASQLVATPSLEL-------------- 613 S P G P PP++ PPS L T L L Sbjct: 554 STKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTEC 613 Query: 614 ----------GPIPAGEEK--------ALELPLAASSIPRPRTPSPESHRSPAEGSERLS 655 P P E ++ L P P +P P+ +P + +S Sbjct: 614 QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673 Query: 656 LSPLRGGEAGP--DASPTVTTPTVTTPSLPAEV-------GSPHSTEVDESLSVSFEQVL 706 S + + P DA+P P P + GSP + + S + Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 707 P---PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPC----EFEHRKAVPMAPAPAS 759 P PS P+ + + P+ + P DL S + K A + Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKP-TTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792 Query: 760 PGSSNDSSARSQ------ERAGGLGAEETP-PTSVSESLPTLSDSDPVPLAPGAADSD-- 810 P DS+ SQ E+ ++ P P S S+ +S P + G D Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK---IISHPGPSSESKGQKQVDPV 849 Query: 811 --EDTEGFGVPRHDPLPDPLKVP-----PPLPDPSSICMVDPEMLPPKTARQTENVSRTR 863 ++ + P PD +P PP P P++ V PK Q+ S Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909 Query: 864 KPLA-RPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEP---SEKGGRAPLSR--K 917 + P S+ P+ T G + +AS +S +P S+ G AP+ + Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA 969 Query: 918 SSTPKTATRGPSGSASSRPGVSATPP 943 S P T+ P + + P + + P Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIP 995 Score = 53.1 bits (126), Expect = 1e-06 Identities = 117/546 (21%), Positives = 180/546 (32%), Gaps = 101/546 (18%) Query: 371 PLSRGPVPAKP-----TVLFEKMGVGR------LDMYVLHPPSAGAERTLASVC---ALL 416 P ++ P PAKP T + G G+ + PPS G +T+ +C LL Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL 598 Query: 417 VWHPAGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLRE-------------------- 456 + P EK C C L G HL ++E Sbjct: 599 LHVP----EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP 654 Query: 457 ----------PVVT----------PQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQ 496 PV T PQ A K+ + K+ L P Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL-H 713 Query: 497 ERPGVARKEPARAEAPRKTE--KEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKT 554 P K+P A++ K KE P E K P QP+ V+ V + T Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773 Query: 555 NAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELG 614 P + PP+ P ++ PP+ SP Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKP-----SQSFPPTGEKVSPFDSKAI------- 821 Query: 615 PIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTT 674 P PA + K + P +S + P + + ++ +SP + P SPT Sbjct: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ-TKMSPKPDAKPMPKGSPTPPG 880 Query: 675 PTVTT-PSLPAEVGSPHSTEVDESLSVSFEQV--LPPSAPTS-EAGLSLPLRGPRARRSA 730 P T ++P SP E S++ + P S PT+ + ++ L G A S Sbjct: 881 PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA--SI 938 Query: 731 SPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSES 790 +L + H ++ P AP +P S +++ PP S ++ Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG------------PPKSTGQA 986 Query: 791 LPTLSDSDPV---PLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPE- 846 P + S PV AP A + E + + K PPP+ D S+ +P+ Sbjct: 987 PPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR---TETEKKPPPIKDSKSL-TAEPQK 1042 Query: 847 -MLPPK 851 +LP K Sbjct: 1043 AVLPTK 1048 Score = 48.1 bits (113), Expect = 4e-05 Identities = 113/527 (21%), Positives = 177/527 (33%), Gaps = 100/527 (18%) Query: 461 PQDLEGPGRAES-----KESVGSRDSSKREGLLATHPRPGQERPGVAR-----------K 504 P+ P AES K+ + S K+ G RP Q PG+++ K Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ--PGLSKSRTTDTFRSEQK 124 Query: 505 EPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRR--AASSVPNL---------KK 553 P R+ + KE+K+ +LK++ K S+ EV A SSV N + Sbjct: 125 LPGRSPSTISL-KESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183 Query: 554 TNAQAAPKPRKAPSTSHSG-----FPPVANGPRSPPSLRCGEASPPSAACGSPASQLVAT 608 + + K +K PP+ P P + G P G+P S Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243 Query: 609 PSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDA 668 P ++ P G K ++ P + P P + + + GE+ + Sbjct: 244 PE-KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP-----QTKQADIVRGESVKPS 297 Query: 669 SPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARR 728 P+ + P + P+ G P + + S Q P P +GL+ PL + Sbjct: 298 LPSPSKPPIQQPT----PGKPPAQQPGHEKS----QPGPAKPPAQPSGLTKPLA--QQPG 347 Query: 729 SASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVS 788 + P V P A P+ PA P S S E+ G + P + Sbjct: 348 TVKPP------VQPPGTTKPPAQPLGPAKP-PAQQTGSEKPSSEQPGPKALAQPPGVGKT 400 Query: 789 ESL-------PTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSIC 841 + PT P PLA G P P P K P P P I Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLA--------QQPGLQSPA--KAPGPTKTPVQQPGPGKI- 449 Query: 842 MVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSA 901 P + A + ++ P +P S+ P P +P A Sbjct: 450 -------PAQQAGPGKTSAQQTGP-TKPPSQLPGPAKPP--------------PQQPGPA 487 Query: 902 RSEPSEKGGRAPLSRK--SSTPKTATRGPSGSASSRPGVSATPPKSP 946 + P + G P S++ S+ P GP+ + +PG + P + P Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534 Score = 34.7 bits (78), Expect = 0.49 Identities = 61/246 (24%), Positives = 90/246 (36%), Gaps = 44/246 (17%) Query: 476 VGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPS-VS 534 V + SS GL+ TH RP +P +A K P + P T+K P ++ PKP+ +S Sbjct: 2486 VPPKPSSIPSGLVFTH-RPEPSKPPIAPK-PVIPQLPTTTQK----PTDIH--PKPTGLS 2537 Query: 535 RTQPREVRRAASSVPNLKKTNAQAAPKPRKAP---STSHSGFPPVANGPRSPPSLRCGEA 591 T + S+ L + +P K+ S S + V P P + A Sbjct: 2538 LTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA 2597 Query: 592 SPP--SAACGSPASQLVAT-------PSLELGPIPAGEEKALELPLAASSIPRPRTPSPE 642 S S GSP+ LV+ P + IP E+ + A + +P Sbjct: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPS 2657 Query: 643 SHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSF 702 S + A+PT T +TT EV + ST LS S Sbjct: 2658 SFQ----------------------AAPTSVTQFLTTEVSKTEVSATRSTAPSVGLS-SI 2694 Query: 703 EQVLPP 708 +PP Sbjct: 2695 SITIPP 2700 Score = 32.3 bits (72), Expect = 2.4 Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 9/140 (6%) Query: 514 KTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGF 573 + + + ++P+ L P + +P + SS T Q AP P K+P +S Sbjct: 3570 EADSDTQSPQYLSATSPPK-DKKRPTPLEIGYSSHLRADST-VQLAPSPPKSPKVLYSPI 3627 Query: 574 PPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSI 633 P++ G + E P + Q V P ++ +P K ++ + S Sbjct: 3628 SPLSPGKALESAFVPYEKPLPD----DISPQKVLHP--DMAKVPPASPKTAKMMQRSMSD 3681 Query: 634 PRPRTP-SPESHRSPAEGSE 652 P+P +P + ES R+P + +E Sbjct: 3682 PKPLSPTADESSRAPFQYTE 3701 Score = 31.6 bits (70), Expect = 4.1 Identities = 67/280 (23%), Positives = 91/280 (32%), Gaps = 44/280 (15%) Query: 531 PSVSR--TQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSP----- 583 PSVS +PR R++S ++ P P P PP P SP Sbjct: 2381 PSVSSLPAKPRPFFRSSSL--DISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIL 2438 Query: 584 PSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPES 643 P + ASP + A +P V T L L + ++ P P P P S Sbjct: 2439 PKKKLTVASPVTTA--TPLFDAVTT----LETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492 Query: 644 HRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSP---HSTEVDESLSV 700 S + R P+ S P P LP P H SL+ Sbjct: 2493 IPSGLVFTHR------------PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540 Query: 701 SFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASP 760 S L SA + PL P + +S+ L + + P+ P Sbjct: 2541 SMTLNLVTSADYKLPSPTSPL-SPHSNKSSPRFSKSLT----------ETYVVITLPSEP 2589 Query: 761 GSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPV 800 G+ DSSA + LG+ SV P S PV Sbjct: 2590 GTPTDSSASQAITSWPLGSPSKDLVSVE---PVFSVVPPV 2626 Score = 30.8 bits (68), Expect = 7.1 Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 15/113 (13%) Query: 774 AGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPP 833 +G +E P + + P++S S P P S D P P P P PPP Sbjct: 2363 SGETFGQEKPASQLPSGSPSVS-SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPP 2421 Query: 834 LPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKT 886 P P LPP T+ + + + + +A P ATP+ A T Sbjct: 2422 PPPPP---------LPPPTSPKPTILPKKKLTVASP-----VTTATPLFDAVT 2460 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 68.6 bits (166), Expect = 3e-11 Identities = 137/584 (23%), Positives = 212/584 (36%), Gaps = 103/584 (17%) Query: 433 PGCTPPACLLDGLVR--LQHLRFLREPVVTPQDLE------GPGRAESKESVGSRDSSKR 484 PG P GL + Q ++ PV P + GP + ++++ + SS++ Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385 Query: 485 EGLLATHPRPGQERPGVARKEPARAEAPRKTE-KEAKTPRELKKDP-------KPSVSRT 536 G P+ + PGV K PA+ P K ++ TP+ L + P P ++T Sbjct: 386 PG-----PKALAQPPGVG-KTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439 Query: 537 ---QPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASP 593 QP + A K + Q P + + PP GP PP + G A P Sbjct: 440 PVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKP 499 Query: 594 PSAACGSPASQLVATPSLELGPI-PAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSE 652 PS GS P + GP P+ ++ P S P PS + SPA+ S Sbjct: 500 PSQQPGS-----TKPPPQQPGPAKPSPQQPGSTKP--PSQQPGSAKPSAQ-QPSPAKPSA 551 Query: 653 RLSLSPLRGGEAGPDASPTVTTPTVTTP---SLPAEVGSPHSTEVDESLSVSFEQVLPPS 709 + S P+ +G P +P+ P LP + P + L V + Sbjct: 552 QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI-CPLCNTTELLLHVPEKANFNTC 610 Query: 710 APTSEAGLSLPLRGPRARRSASPH--DVDLCLVSPCEFEHRKAVPMAPAPASP------- 760 SL P +PH +V L C+ + +AP P+SP Sbjct: 611 TECQTTVCSLCGFNP------NPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA 664 Query: 761 -----GSSNDSSARSQERAGGLGA-----------EETPPTSVSESLPTL---------- 794 + + SS + Q+ + A + PP V + PTL Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ--PTLHGSPSAKAKQ 722 Query: 795 -----SDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPD--PSSICMVDPEM 847 S S P P + S++D P D P K+ P D SS P++ Sbjct: 723 PPEADSLSKPAPPKEPSVPSEQDK----APVADDKPKQPKMVKPTTDLVSSSSATTKPDI 778 Query: 848 LPPKTARQTENVSRTRKPL----ARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARS 903 P + Q++ +T PL A+P S++ P V+ +K + S+ +S Sbjct: 779 --PSSKVQSQAEEKTTPPLKTDSAKP-SQSFPPTGEKVSPFDSKAIPRPASDSKIISHPG 835 Query: 904 EPSEKGGRA---PLSRKSSTPKTATR-GPSGSASSRPGVSATPP 943 SE G+ P+ +K K T+ P A P S TPP Sbjct: 836 PSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPP 879 Score = 62.4 bits (150), Expect = 2e-09 Identities = 118/566 (20%), Positives = 194/566 (34%), Gaps = 85/566 (15%) Query: 457 PVVTPQDLEGPGRAESKESVGSRDSSKREG------LLATHPRPGQERPGVARKEPARAE 510 P TP GPG+ ++++ + S+++ G L +P ++PG A+ P + Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG 495 Query: 511 APRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSH 570 + + ++ + + + P P+ Q + S P K +AQ P P K PS Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQ-PSPAK-PSAQQ 553 Query: 571 SGFPPVANG---PRSPPSLRCGEASPPSAACGSPASQLVATPSLEL-------------- 613 S P G P PP++ PPS L T L L Sbjct: 554 STKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTEC 613 Query: 614 ----------GPIPAGEEK--------ALELPLAASSIPRPRTPSPESHRSPAEGSERLS 655 P P E ++ L P P +P P+ +P + +S Sbjct: 614 QTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS 673 Query: 656 LSPLRGGEAGP--DASPTVTTPTVTTPSLPAEV-------GSPHSTEVDESLSVSFEQVL 706 S + + P DA+P P P + GSP + + S + Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 707 P---PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPC----EFEHRKAVPMAPAPAS 759 P PS P+ + + P+ + P DL S + K A + Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKP-TTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792 Query: 760 PGSSNDSSARSQ------ERAGGLGAEETP-PTSVSESLPTLSDSDPVPLAPGAADSD-- 810 P DS+ SQ E+ ++ P P S S+ +S P + G D Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSK---IISHPGPSSESKGQKQVDPV 849 Query: 811 --EDTEGFGVPRHDPLPDPLKVP-----PPLPDPSSICMVDPEMLPPKTARQTENVSRTR 863 ++ + P PD +P PP P P++ V PK Q+ S Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL 909 Query: 864 KPLA-RPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEP---SEKGGRAPLSR--K 917 + P S+ P+ T G + +AS +S +P S+ G AP+ + Sbjct: 910 GSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA 969 Query: 918 SSTPKTATRGPSGSASSRPGVSATPP 943 S P T+ P + + P + + P Sbjct: 970 PSQPPTSQGPPKSTGQAPPAPAKSIP 995 Score = 53.1 bits (126), Expect = 1e-06 Identities = 117/546 (21%), Positives = 180/546 (32%), Gaps = 101/546 (18%) Query: 371 PLSRGPVPAKP-----TVLFEKMGVGR------LDMYVLHPPSAGAERTLASVC---ALL 416 P ++ P PAKP T + G G+ + PPS G +T+ +C LL Sbjct: 539 PSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELL 598 Query: 417 VWHPAGPGEKVVRVLFPGCTPPACLLDGLVRLQHLRFLRE-------------------- 456 + P EK C C L G HL ++E Sbjct: 599 LHVP----EKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVP 654 Query: 457 ----------PVVT----------PQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQ 496 PV T PQ A K+ + K+ L P Sbjct: 655 SSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTL-H 713 Query: 497 ERPGVARKEPARAEAPRKTE--KEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKT 554 P K+P A++ K KE P E K P QP+ V+ V + T Sbjct: 714 GSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSAT 773 Query: 555 NAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELG 614 P + PP+ P ++ PP+ SP Sbjct: 774 TKPDIPSSKVQSQAEEKTTPPLKTDSAKP-----SQSFPPTGEKVSPFDSKAI------- 821 Query: 615 PIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTT 674 P PA + K + P +S + P + + ++ +SP + P SPT Sbjct: 822 PRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQ-TKMSPKPDAKPMPKGSPTPPG 880 Query: 675 PTVTT-PSLPAEVGSPHSTEVDESLSVSFEQV--LPPSAPTS-EAGLSLPLRGPRARRSA 730 P T ++P SP E S++ + P S PT+ + ++ L G A S Sbjct: 881 PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGA--SI 938 Query: 731 SPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSES 790 +L + H ++ P AP +P S +++ PP S ++ Sbjct: 939 FSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQG------------PPKSTGQA 986 Query: 791 LPTLSDSDPV---PLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPE- 846 P + S PV AP A + E + + K PPP+ D S+ +P+ Sbjct: 987 PPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR---TETEKKPPPIKDSKSL-TAEPQK 1042 Query: 847 -MLPPK 851 +LP K Sbjct: 1043 AVLPTK 1048 Score = 48.1 bits (113), Expect = 4e-05 Identities = 113/527 (21%), Positives = 177/527 (33%), Gaps = 100/527 (18%) Query: 461 PQDLEGPGRAES-----KESVGSRDSSKREGLLATHPRPGQERPGVAR-----------K 504 P+ P AES K+ + S K+ G RP Q PG+++ K Sbjct: 67 PKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQ--PGLSKSRTTDTFRSEQK 124 Query: 505 EPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRR--AASSVPNL---------KK 553 P R+ + KE+K+ +LK++ K S+ EV A SSV N + Sbjct: 125 LPGRSPSTISL-KESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSE 183 Query: 554 TNAQAAPKPRKAPSTSHSG-----FPPVANGPRSPPSLRCGEASPPSAACGSPASQLVAT 608 + + K +K PP+ P P + G P G+P S Sbjct: 184 ASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQ 243 Query: 609 PSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDA 668 P ++ P G K ++ P + P P + + + GE+ + Sbjct: 244 PE-KIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRP-----QTKQADIVRGESVKPS 297 Query: 669 SPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARR 728 P+ + P + P+ G P + + S Q P P +GL+ PL + Sbjct: 298 LPSPSKPPIQQPT----PGKPPAQQPGHEKS----QPGPAKPPAQPSGLTKPLA--QQPG 347 Query: 729 SASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVS 788 + P V P A P+ PA P S S E+ G + P + Sbjct: 348 TVKPP------VQPPGTTKPPAQPLGPAKP-PAQQTGSEKPSSEQPGPKALAQPPGVGKT 400 Query: 789 ESL-------PTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSIC 841 + PT P PLA G P P P K P P P I Sbjct: 401 PAQQPGPAKPPTQQVGTPKPLA--------QQPGLQSPA--KAPGPTKTPVQQPGPGKI- 449 Query: 842 MVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSA 901 P + A + ++ P +P S+ P P +P A Sbjct: 450 -------PAQQAGPGKTSAQQTGP-TKPPSQLPGPAKPP--------------PQQPGPA 487 Query: 902 RSEPSEKGGRAPLSRK--SSTPKTATRGPSGSASSRPGVSATPPKSP 946 + P + G P S++ S+ P GP+ + +PG + P + P Sbjct: 488 KPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQP 534 Score = 34.7 bits (78), Expect = 0.49 Identities = 61/246 (24%), Positives = 90/246 (36%), Gaps = 44/246 (17%) Query: 476 VGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPS-VS 534 V + SS GL+ TH RP +P +A K P + P T+K P ++ PKP+ +S Sbjct: 2486 VPPKPSSIPSGLVFTH-RPEPSKPPIAPK-PVIPQLPTTTQK----PTDIH--PKPTGLS 2537 Query: 535 RTQPREVRRAASSVPNLKKTNAQAAPKPRKAP---STSHSGFPPVANGPRSPPSLRCGEA 591 T + S+ L + +P K+ S S + V P P + A Sbjct: 2538 LTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSA 2597 Query: 592 SPP--SAACGSPASQLVAT-------PSLELGPIPAGEEKALELPLAASSIPRPRTPSPE 642 S S GSP+ LV+ P + IP E+ + A + +P Sbjct: 2598 SQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPS 2657 Query: 643 SHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSF 702 S + A+PT T +TT EV + ST LS S Sbjct: 2658 SFQ----------------------AAPTSVTQFLTTEVSKTEVSATRSTAPSVGLS-SI 2694 Query: 703 EQVLPP 708 +PP Sbjct: 2695 SITIPP 2700 Score = 32.3 bits (72), Expect = 2.4 Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 9/140 (6%) Query: 514 KTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGF 573 + + + ++P+ L P + +P + SS T Q AP P K+P +S Sbjct: 3570 EADSDTQSPQYLSATSPPK-DKKRPTPLEIGYSSHLRADST-VQLAPSPPKSPKVLYSPI 3627 Query: 574 PPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSI 633 P++ G + E P + Q V P ++ +P K ++ + S Sbjct: 3628 SPLSPGKALESAFVPYEKPLPD----DISPQKVLHP--DMAKVPPASPKTAKMMQRSMSD 3681 Query: 634 PRPRTP-SPESHRSPAEGSE 652 P+P +P + ES R+P + +E Sbjct: 3682 PKPLSPTADESSRAPFQYTE 3701 Score = 31.6 bits (70), Expect = 4.1 Identities = 67/280 (23%), Positives = 91/280 (32%), Gaps = 44/280 (15%) Query: 531 PSVSR--TQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSP----- 583 PSVS +PR R++S ++ P P P PP P SP Sbjct: 2381 PSVSSLPAKPRPFFRSSSL--DISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTIL 2438 Query: 584 PSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPES 643 P + ASP + A +P V T L L + ++ P P P P S Sbjct: 2439 PKKKLTVASPVTTA--TPLFDAVTT----LETTAVLRSNGLPVTRICTTAPPPVPPKPSS 2492 Query: 644 HRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSP---HSTEVDESLSV 700 S + R P+ S P P LP P H SL+ Sbjct: 2493 IPSGLVFTHR------------PEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTS 2540 Query: 701 SFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASP 760 S L SA + PL P + +S+ L + + P+ P Sbjct: 2541 SMTLNLVTSADYKLPSPTSPL-SPHSNKSSPRFSKSLT----------ETYVVITLPSEP 2589 Query: 761 GSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPV 800 G+ DSSA + LG+ SV P S PV Sbjct: 2590 GTPTDSSASQAITSWPLGSPSKDLVSVE---PVFSVVPPV 2626 Score = 30.8 bits (68), Expect = 7.1 Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 15/113 (13%) Query: 774 AGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPP 833 +G +E P + + P++S S P P S D P P P P PPP Sbjct: 2363 SGETFGQEKPASQLPSGSPSVS-SLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPP 2421 Query: 834 LPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKT 886 P P LPP T+ + + + + +A P ATP+ A T Sbjct: 2422 PPPPP---------LPPPTSPKPTILPKKKLTVASP-----VTTATPLFDAVT 2460 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 67.8 bits (164), Expect = 5e-11 Identities = 120/476 (25%), Positives = 170/476 (35%), Gaps = 85/476 (17%) Query: 521 TPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGP 580 TP + P V QP A S P A +P +AP T + PP A P Sbjct: 607 TPAAATGEAAP-VLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAP-TPQAAAPPQATTP 664 Query: 581 RSPPSLRCGEASPPSAACGSPASQ----LVATPSLEL--------GPIPAGEEKALELPL 628 + P L +SP G P S ++ SL++ P+ A E L +P Sbjct: 665 QPSPGLA---SSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSA-EGPHLSVPA 720 Query: 629 AA-------SSIPRPRTP----------SPESHRSPAEGSERLSLSPLRGGEAGPDASPT 671 + + P P TP +P+S SPA + + +PL+G GP +SP+ Sbjct: 721 SVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKG--PGPSSSPS 778 Query: 672 V--TTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSE-AGLSLPLRGPRARR 728 + P +P LP SPH T PPS P S +S P P Sbjct: 779 LPHQAPLGDSPHLP----SPHPTR-------------PPSRPPSRPQSVSRPPSEP-PLH 820 Query: 729 SASPHDVDLCLVSPCEFEHRKAVP---MAPAPASPGSSNDS-SARSQERAGGL-GAEETP 783 P L +++ VP PAP +PG +SQ G L A P Sbjct: 821 PCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLP 880 Query: 784 PTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPL------KVPPPLPDP 837 P+S S ++ + S++ AP +D P P P P PP P P Sbjct: 881 PSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPP 940 Query: 838 SSICMV--------DPEMLPPKTARQTENVSRTRK----PLARPNSRAAAPKATPVAAAK 885 + MV P+ L + + + K P A S + P +P A+ Sbjct: 941 RTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVL 1000 Query: 886 TKGLAGGDRASRPLSARS-EPSEKGGRAPL---SRKSSTPKTATRGPSGSASSRPG 937 G A + P A + P G PL K+ T + +ASS PG Sbjct: 1001 VSGQAPSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPG 1056 Score = 34.3 bits (77), Expect = 0.64 Identities = 59/240 (24%), Positives = 75/240 (31%), Gaps = 44/240 (18%) Query: 371 PLSRGPVPAKPTVLFEKMGVGRLDMYVLHPPSAGAERTLASVCALLVWHPAGPGEKVVRV 430 P R P P PT G+++ V HPP A ER P P K R Sbjct: 1345 PPPRPPPPPPPT--------GQMNGTVDHPPPAAPERKPLGTAPHC---PRLPLRKTYRE 1393 Query: 431 LFPGCTPPACLLDGLVRLQHLRFLREPVVTPQDLEGPGRAESKESVGSRDSSKREGLLAT 490 G P G R P P ++ +E D + L Sbjct: 1394 NVGGPGAPEGTPAGRARGG------SPAPLPAKVDEATSGLIRELAAVEDELYQRMLKGP 1447 Query: 491 HPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSR-----------TQPR 539 P P A+ E P + +K P V + T Sbjct: 1448 PPEPAASA--------AQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTE 1499 Query: 540 EVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACG 599 ++ A S+ NL Q AP APS H+ A P SPP L EA PPS+ G Sbjct: 1500 HLQSAIDSILNL-----QQAPGRTPAPSYPHAAS---AGTPASPPPLHRPEAYPPSSHNG 1551 Score = 33.1 bits (74), Expect = 1.4 Identities = 60/233 (25%), Positives = 82/233 (35%), Gaps = 21/233 (9%) Query: 695 DESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMA 754 DE +S S LP +A S G LP GP + S++P P + + Sbjct: 1199 DEYVSSSRSLGLPIAA--SSEGHRLPGHGPLS--SSAP---GASTQPPPHLPTKLVIRHG 1251 Query: 755 PAPASPG-------SSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAA 807 A SP SS SS+ S A L A+E P S + P + + G Sbjct: 1252 GAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMP-SRNRPPIKTYEARSRI-GLK 1309 Query: 808 DSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLA 867 + G H+ DP+ PPP P + P PP N + P A Sbjct: 1310 LKIKQEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPA 1369 Query: 868 RPNSR--AAAPKATPVAAAKT-KGLAGGDRASRPLSARSEPSEKGGRAPLSRK 917 P + AP + KT + GG A P + + G APL K Sbjct: 1370 APERKPLGTAPHCPRLPLRKTYRENVGGPGA--PEGTPAGRARGGSPAPLPAK 1420 Score = 32.0 bits (71), Expect = 3.2 Identities = 87/392 (22%), Positives = 120/392 (30%), Gaps = 82/392 (20%) Query: 620 EEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTT 679 +EK E ++ S+ P S E HR P G PL G P PT Sbjct: 1195 KEKPDEYVSSSRSLGLPIAASSEGHRLPGHG-------PLSSSAPGASTQPPPHLPTKLV 1247 Query: 680 PSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEA-----------------------G 716 GSP T S S+S +A + +A G Sbjct: 1248 IRHGGAGGSPSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIG 1307 Query: 717 LSLPLRGPRARRSASPHDVDLCLV-----SPCEFEHRKAVPMAPAPASP-GSSNDSSARS 770 L L ++ A S H+ L V P + + P P P P G N Sbjct: 1308 LKLKIK-QEAGLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMN------ 1360 Query: 771 QERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKV 830 G + PP + E P L + P P E+ G G P P + Sbjct: 1361 -------GTVDHPPPAAPERKP-LGTAPHCPRLPLRKTYRENVGGPGAPEGTP-AGRARG 1411 Query: 831 PPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLA 890 P P P+ + ++ A + E R K P A+A + T + GL Sbjct: 1412 GSPAPLPAKVDEATSGLIRELAAVEDELYQRMLKG-PPPEPAASAAQGTGDPDWEAPGLP 1470 Query: 891 GGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATR--------------------GPSG 930 P R S +A S S T T PS Sbjct: 1471 -------PAKRRKSESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSY 1523 Query: 931 SASSRPGVSATPPKSPVYLDLAYLPSGSSAHL 962 ++ G A+PP P++ AY PS + L Sbjct: 1524 PHAASAGTPASPP--PLHRPEAYPPSSHNGGL 1553 >gi|148727255 microtubule associated serine/threonine kinase family member 4 isoform a [Homo sapiens] Length = 2434 Score = 66.6 bits (161), Expect = 1e-10 Identities = 137/533 (25%), Positives = 183/533 (34%), Gaps = 87/533 (16%) Query: 467 PGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKE--PARAEAPRKTEKEAKTPRE 524 P + S+E G R+SS+R P AR E ARA+ R+ E P Sbjct: 1770 PEASPSREKPGLRESSERG-------------PPTARSERSAARADTCREPSMELCFPET 1816 Query: 525 LKKDPKP----SVSRTQP--------REVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSG 572 K SV RT P E A N K +A P PR S +G Sbjct: 1817 AKTSDNSKNLLSVGRTHPDFYTQTQAMEKAWAPGGKTNHKDGPGEARPPPRDNSSLHSAG 1876 Query: 573 FP------PVANGPR-SPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALE 625 P V G P +L + P + +L + PSL+ E K Sbjct: 1877 IPCEKELGKVRRGVEPKPEALLARRSLQPPGIESEKSEKLSSFPSLQKDGAKEPERKEQP 1936 Query: 626 LPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAE 685 L SSIP P + + SPA S S G E P A P+ P+ ++P P + Sbjct: 1937 LQRHPSSIPPPPLTAKDL-SSPAARQHCSSPSHASGRE--PGAKPSTAEPS-SSPQDPPK 1992 Query: 686 VGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEF 745 + HS E PP + LS A + P L S Sbjct: 1993 PVAAHS-ESSSHKPRPGPDPGPPKTKHPDRSLSSQKPSVGATKGKEPATQSLGGSSREGK 2051 Query: 746 EHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPG 805 H K+ P PA+PGS N +S G+G E P S+P +D P+ P Sbjct: 2052 GHSKSGPDV-FPATPGSQNKAS-------DGIGQGEGGP-----SVPLHTDRAPLDAKPQ 2098 Query: 806 AADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMV-DPEMLPPK------------T 852 E P H LP P P P + V + + L PK Sbjct: 2099 PTSGGRPLEVLEKPVH--LPRPGHPGPSEPADQKLSAVGEKQTLSPKHPKPSTVKDCPTL 2156 Query: 853 ARQTENVSRTR---KPLARPNSRAAAPKATPVAAAKTKG--LAGG----------DRASR 897 +QT+N + +P A + RA K T A +G L G A R Sbjct: 2157 CKQTDNRQTDKSPSQPAANTDRRAEGKKCTEALYAPAEGDKLEAGLSFVHSENRLKGAER 2216 Query: 898 PLSARSEP-SEKGGRAPLSRKSST----PKTATRGPSGSASSRPGVSATPPKS 945 P + + E G+ P +K T P R PS + S +A P KS Sbjct: 2217 PAAGVGKGFPEARGKGPGPQKPPTEADKPNGMKRSPSATGQSSFRSTALPEKS 2269 Score = 38.1 bits (87), Expect = 0.044 Identities = 58/231 (25%), Positives = 92/231 (39%), Gaps = 36/231 (15%) Query: 498 RPGVARKEPARAEAPRKTEKEAKTP---------RELKKDPKPSVSRTQPRE-VRRAASS 547 + G AR+ ++ R+++K K ++L K P P + ++ + R+ SS Sbjct: 1045 KTGPARRNSYKSRMVRRSKKSKKKESLERRRSLFKKLAKQPSPLLHTSRSFSCLNRSLSS 1104 Query: 548 VPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVA 607 +L + + PR +P+ S+ P +G S S +SP S+A SPA Sbjct: 1105 GESLPGSPTHSL-SPR-SPTPSYRSTPDFPSGTNSSQS-----SSPSSSAPNSPAGSGHI 1157 Query: 608 TPSLELGPIP--------AGEEKALE----LPLAASSIPRPRTPSPESHRSPAEGSERLS 655 PS G P +G K+ PLA + P P+ SP+ SP G S Sbjct: 1158 RPSTLHGLAPKLGGQRYRSGRRKSAGNIPLSPLARTPSPTPQPTSPQRSPSPLLGH---S 1214 Query: 656 LSPLRGGEAGPDA--SPTVTTPTVTTPSLPAEVGSP--HSTEVDESLSVSF 702 L + +A P SP + P SP + +E LS S+ Sbjct: 1215 LGNSKIAQAFPSKMHSPPTIVRHIVRPKSAEPPRSPLLKRVQSEEKLSPSY 1265 >gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] Length = 1020 Score = 66.2 bits (160), Expect = 2e-10 Identities = 118/572 (20%), Positives = 200/572 (34%), Gaps = 110/572 (19%) Query: 459 VTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVAR----------KEPAR 508 VT ++ + E KE G + G T P +E + K PA Sbjct: 470 VTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAE 529 Query: 509 AEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQA-----APKPR 563 A++P K +EAK+P E+K P +++ +E ++ + +K A++ +P+ Sbjct: 530 AKSPEK--EEAKSPAEVK---SPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584 Query: 564 KAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATP----SLELGPIPAG 619 K+P+ + P A P S EA P+ A SP + +P S E P Sbjct: 585 KSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEA-KSPVKEEAKSPAEVKSPEKAKSPTK 643 Query: 620 EEKALELPLAASSIPRPRTPSPESHRSPAEG---SERLSLSPLRGGEAGPDASPTVTTPT 676 EE + P A S + SPE +SP + S + SP++ P+ + + Sbjct: 644 EE--AKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEE 701 Query: 677 VTTPS-----LPAEVGSPH----------STEVDESLSVSFEQVLPPSAPTSEAGLSLPL 721 +P + E SP T V E P A + E +L + Sbjct: 702 AKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761 Query: 722 RGPRARRSA-----SPHDVDLCLVSPCEFEHRKAVPM-----APAPASPGSSNDSSA--- 768 + P A+ A SP D +F + P+ +P A D+ A Sbjct: 762 KSPEAKTPAKEEARSPAD---------KFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEK 812 Query: 769 ---RSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLP 825 + +E + EE P + P ++ + P P + + + + P P Sbjct: 813 EIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872 Query: 826 --------------------------DPLKVPPPLPDPSSICMVDPEMLP---PKTARQT 856 D KVP P + + V + P + A++ Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKE 932 Query: 857 ENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSR 916 + ++ ++P + AAP+ K K +P ++E K LS+ Sbjct: 933 PDDAKAKEPSKPAEKKEAAPEKKDTKEEKAK-----KPEEKP---KTEAKAKEDDKTLSK 984 Query: 917 KSSTPKTATRGPSGSA---SSRPGVSATPPKS 945 + S PK S S S+P AT K+ Sbjct: 985 EPSKPKAEKAEKSSSTDQKDSKPPEKATEDKA 1016 Score = 39.7 bits (91), Expect = 0.015 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 8/116 (6%) Query: 454 LREPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPR 513 ++EP ++ + P +++E +DS K E P+P E +KEPA E P+ Sbjct: 835 VKEPPKKAEEEKAPATPKTEEK---KDSKKEEAPKKEAPKPKVEE----KKEPA-VEKPK 886 Query: 514 KTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTS 569 +++ EAK K P+ + P +V + P K A+ P KA S Sbjct: 887 ESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS 942 >gi|149773456 hypothetical protein LOC643314 [Homo sapiens] Length = 1427 Score = 65.9 bits (159), Expect = 2e-10 Identities = 94/374 (25%), Positives = 134/374 (35%), Gaps = 52/374 (13%) Query: 494 PGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKK 553 P E P E P TP E P+ + P E A++VP ++ Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTPEE---PTSPAAAVPTPEEPTSPAAAVPTPEE 1077 Query: 554 TNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLEL 613 + AA P TS + P P SP + P S A P + A+P+ Sbjct: 1078 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPA--- 1134 Query: 614 GPIPAGEEKALELPLAASSIPRPR--------TPSPESHRSPAEG----SERLSLSPLRG 661 +P EE A P ++P P P+PE SPA +E S + + Sbjct: 1135 AAVPTPEEPAFPAP----AVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA 1190 Query: 662 GEAGPDASPTVTTPT-----VTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAG 716 P SP + PT T + S ++E SL+ + V P PTS A Sbjct: 1191 TLEEP-TSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAA---VSNPEEPTSPAA 1246 Query: 717 LSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGG 776 L P + +A +++P E A P P P S + + +E A Sbjct: 1247 AVPTLEEPTSSAAA--------VLTPEELSSPAA--SVPTPEEPASPAAAVSNLEEPASP 1296 Query: 777 LGAEETPPTSVSESLPTLSDSDP-VPLAPGAA-DSDEDTEGFGVP------RHDPLPDPL 828 A TP + ++P S P VP P AA E+ GVP D +P Sbjct: 1297 AAAVPTPEVA---AIPAASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISE 1353 Query: 829 KVPPPLPDPSSICM 842 + P L + SS M Sbjct: 1354 EGTPVLEEASSTGM 1367 Score = 63.2 bits (152), Expect = 1e-09 Identities = 94/400 (23%), Positives = 133/400 (33%), Gaps = 85/400 (21%) Query: 497 ERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNA 556 E P A + E P TP E P+ + P E A++VP ++ + Sbjct: 985 EEPDTAAVRVSTPEEPASPAAAVPTPEE---PTSPAAAVPTPEEPTSPAAAVPPPEEPTS 1041 Query: 557 QAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPI 616 AA P TS + P P SP + P S A P + +P+ + Sbjct: 1042 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA---AAV 1098 Query: 617 PAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPT 676 P EE + P P+PE SPA ASP PT Sbjct: 1099 PTPEE---------PTSPAAAVPTPEEPASPAAAVP----------TPEEPASPAAAVPT 1139 Query: 677 VTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVD 736 P+ PA P+ PT E S + P SASP Sbjct: 1140 PEEPAFPA-----------------------PAVPTPEESASAAVAVPTPEESASP---A 1173 Query: 737 LCLVSPCEFEHRKA-VPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLS 795 + +P E A V P SP +S + A + A TS + S+PT Sbjct: 1174 AAVPTPAESASFAAVVATLEEPTSPAASVPTPA-------AMVATLEEFTSPAASVPT-- 1224 Query: 796 DSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDP--SSICMVDPEML----- 848 +P LA ++ +E T P P L +P S+ ++ PE L Sbjct: 1225 SEEPASLAAAVSNPEEPT------------SPAAAVPTLEEPTSSAAAVLTPEELSSPAA 1272 Query: 849 ----PPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAA 884 P + A VS +P A P + P+ + AA Sbjct: 1273 SVPTPEEPASPAAAVSNLEEP-ASPAAAVPTPEVAAIPAA 1311 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 65.9 bits (159), Expect = 2e-10 Identities = 130/546 (23%), Positives = 192/546 (35%), Gaps = 84/546 (15%) Query: 461 PQDLEGPGRAES------KESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRK 514 P+D++ R+ S +++ DSS ++ +L P Q GV PA + AP Sbjct: 147 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT---PAPSSAPPG 203 Query: 515 TEK---EAKTPRELKKDPKPSVSRTQ-PREVRRAASSVPNLKKTNAQAAPK--PRKAPST 568 T + TP P+ S + +Q P + + + VP+ T+ Q AP P++ PS Sbjct: 204 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH---THIQQAPALHPQRPPSP 260 Query: 569 SHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATP-SLELGPI--PAGEEKALE 625 H P + P P + G+ S PS A Q P SL+ GP+ G + Sbjct: 261 -HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG 319 Query: 626 LPLAASSIPRPRTPSPES---HRS---PAEGSERLSLSPLRGGE------AGPDASPTVT 673 LP AS P SP + H S PA S S P R A P P T Sbjct: 320 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 379 Query: 674 TPTVTTPSLPAEVGSPH-------------------------STEVDESLSVSFEQVLP- 707 TP P+ A PH ST S Q++P Sbjct: 380 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 439 Query: 708 ----PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSS 763 PS+P GL+ P S P + P F VP P P +P + Sbjct: 440 SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP-PFAQHPFVPGGPPPITPPTC 498 Query: 764 NDSSARSQERAGGLGAEETPPTS---VSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPR 820 +S G G PP S S S P+P ++ +D E Sbjct: 499 PSTSTPP----AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE------ 548 Query: 821 HDPLPDPLKVPPPLPDPS-SICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKAT 879 +P PPP PS +VD ++AR +++ R AR + + Sbjct: 549 -----EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGS 603 Query: 880 PVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVS 939 +A + + + R + + EK R+ + A R S+S+ G Sbjct: 604 KLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRL 663 Query: 940 ATPPKS 945 + P S Sbjct: 664 SDPQLS 669 Score = 48.5 bits (114), Expect = 3e-05 Identities = 98/488 (20%), Positives = 162/488 (33%), Gaps = 76/488 (15%) Query: 496 QERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQP--REVRRAASSVPNLKK 553 +E G++ K R R + ++ R KK P RT P ++R + + P+ Sbjct: 7 EEDDGLSGKHSMRTRRSRGSMSTLRSGR--KKQPASPDGRTSPINEDIRSSGRNSPSAAS 64 Query: 554 TNA---QAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATP- 609 T++ +A + A P+ + R + + +Q ++ P Sbjct: 65 TSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPN 124 Query: 610 -----------SLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSP 658 S + + + K ++ ++S P PSP+ + S ++ S + + Sbjct: 125 SPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS---PSIPSPQDNESDSDSSAQQQML- 180 Query: 659 LRGGEAGPDA--SPTVTTPTVT-----TPSLPAEVGSPHSTEVDESLSVSFEQVL-PPSA 710 +A P A +PT TP + TP LP +P +T V S + Q P A Sbjct: 181 ----QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 236 Query: 711 PTSEAGLSLPLRGP--RARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSA 768 PT+ + + P +R SPH P P+P P Sbjct: 237 PTAPVPHTHIQQAPALHPQRPPSPHP-----------------PPHPSPHPP-------- 271 Query: 769 RSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPL 828 Q G G P++ S + P L P PG + + +H P P Sbjct: 272 -LQPLTGSAGQ----PSAPSHAQPPLHGQGP----PGP----HSLQAGPLLQHPGPPQPF 318 Query: 829 KVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKG 888 +PP + P P T+ Q + P + P + K Sbjct: 319 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 378 Query: 889 LAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVY 948 + P A P G +P S ++ P P S S+ SA PP + Sbjct: 379 TTPIPQLPAP-QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 437 Query: 949 LDLAYLPS 956 LPS Sbjct: 438 PQSQPLPS 445 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 65.9 bits (159), Expect = 2e-10 Identities = 130/546 (23%), Positives = 192/546 (35%), Gaps = 84/546 (15%) Query: 461 PQDLEGPGRAES------KESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRK 514 P+D++ R+ S +++ DSS ++ +L P Q GV PA + AP Sbjct: 701 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT---PAPSSAPPG 757 Query: 515 TEK---EAKTPRELKKDPKPSVSRTQ-PREVRRAASSVPNLKKTNAQAAPK--PRKAPST 568 T + TP P+ S + +Q P + + + VP+ T+ Q AP P++ PS Sbjct: 758 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH---THIQQAPALHPQRPPSP 814 Query: 569 SHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATP-SLELGPI--PAGEEKALE 625 H P + P P + G+ S PS A Q P SL+ GP+ G + Sbjct: 815 -HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG 873 Query: 626 LPLAASSIPRPRTPSPES---HRS---PAEGSERLSLSPLRGGE------AGPDASPTVT 673 LP AS P SP + H S PA S S P R A P P T Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 933 Query: 674 TPTVTTPSLPAEVGSPH-------------------------STEVDESLSVSFEQVLP- 707 TP P+ A PH ST S Q++P Sbjct: 934 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993 Query: 708 ----PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSS 763 PS+P GL+ P S P + P F VP P P +P + Sbjct: 994 SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP-PFAQHPFVPGGPPPITPPTC 1052 Query: 764 NDSSARSQERAGGLGAEETPPTS---VSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPR 820 +S G G PP S S S P+P ++ +D E Sbjct: 1053 PSTSTPP----AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE------ 1102 Query: 821 HDPLPDPLKVPPPLPDPS-SICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKAT 879 +P PPP PS +VD ++AR +++ R AR + + Sbjct: 1103 -----EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGS 1157 Query: 880 PVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVS 939 +A + + + R + + EK R+ + A R S+S+ G Sbjct: 1158 KLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRL 1217 Query: 940 ATPPKS 945 + P S Sbjct: 1218 SDPQLS 1223 Score = 48.5 bits (114), Expect = 3e-05 Identities = 98/488 (20%), Positives = 162/488 (33%), Gaps = 76/488 (15%) Query: 496 QERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQP--REVRRAASSVPNLKK 553 +E G++ K R R + ++ R KK P RT P ++R + + P+ Sbjct: 561 EEDDGLSGKHSMRTRRSRGSMSTLRSGR--KKQPASPDGRTSPINEDIRSSGRNSPSAAS 618 Query: 554 TNA---QAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATP- 609 T++ +A + A P+ + R + + +Q ++ P Sbjct: 619 TSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPN 678 Query: 610 -----------SLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSP 658 S + + + K ++ ++S P PSP+ + S ++ S + + Sbjct: 679 SPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS---PSIPSPQDNESDSDSSAQQQML- 734 Query: 659 LRGGEAGPDA--SPTVTTPTVT-----TPSLPAEVGSPHSTEVDESLSVSFEQVL-PPSA 710 +A P A +PT TP + TP LP +P +T V S + Q P A Sbjct: 735 ----QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790 Query: 711 PTSEAGLSLPLRGP--RARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSA 768 PT+ + + P +R SPH P P+P P Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHP-----------------PPHPSPHPP-------- 825 Query: 769 RSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPL 828 Q G G P++ S + P L P PG + + +H P P Sbjct: 826 -LQPLTGSAGQ----PSAPSHAQPPLHGQGP----PGP----HSLQAGPLLQHPGPPQPF 872 Query: 829 KVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKG 888 +PP + P P T+ Q + P + P + K Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932 Query: 889 LAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVY 948 + P A P G +P S ++ P P S S+ SA PP + Sbjct: 933 TTPIPQLPAP-QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991 Query: 949 LDLAYLPS 956 LPS Sbjct: 992 PQSQPLPS 999 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 65.9 bits (159), Expect = 2e-10 Identities = 130/546 (23%), Positives = 192/546 (35%), Gaps = 84/546 (15%) Query: 461 PQDLEGPGRAES------KESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRK 514 P+D++ R+ S +++ DSS ++ +L P Q GV PA + AP Sbjct: 701 PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVT---PAPSSAPPG 757 Query: 515 TEK---EAKTPRELKKDPKPSVSRTQ-PREVRRAASSVPNLKKTNAQAAPK--PRKAPST 568 T + TP P+ S + +Q P + + + VP+ T+ Q AP P++ PS Sbjct: 758 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH---THIQQAPALHPQRPPSP 814 Query: 569 SHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATP-SLELGPI--PAGEEKALE 625 H P + P P + G+ S PS A Q P SL+ GP+ G + Sbjct: 815 -HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFG 873 Query: 626 LPLAASSIPRPRTPSPES---HRS---PAEGSERLSLSPLRGGE------AGPDASPTVT 673 LP AS P SP + H S PA S S P R A P P T Sbjct: 874 LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 933 Query: 674 TPTVTTPSLPAEVGSPH-------------------------STEVDESLSVSFEQVLP- 707 TP P+ A PH ST S Q++P Sbjct: 934 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993 Query: 708 ----PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSS 763 PS+P GL+ P S P + P F VP P P +P + Sbjct: 994 SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQP-PFAQHPFVPGGPPPITPPTC 1052 Query: 764 NDSSARSQERAGGLGAEETPPTS---VSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPR 820 +S G G PP S S S P+P ++ +D E Sbjct: 1053 PSTSTPP----AGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAE------ 1102 Query: 821 HDPLPDPLKVPPPLPDPS-SICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKAT 879 +P PPP PS +VD ++AR +++ R AR + + Sbjct: 1103 -----EPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGS 1157 Query: 880 PVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVS 939 +A + + + R + + EK R+ + A R S+S+ G Sbjct: 1158 KLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRL 1217 Query: 940 ATPPKS 945 + P S Sbjct: 1218 SDPQLS 1223 Score = 48.5 bits (114), Expect = 3e-05 Identities = 98/488 (20%), Positives = 162/488 (33%), Gaps = 76/488 (15%) Query: 496 QERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQP--REVRRAASSVPNLKK 553 +E G++ K R R + ++ R KK P RT P ++R + + P+ Sbjct: 561 EEDDGLSGKHSMRTRRSRGSMSTLRSGR--KKQPASPDGRTSPINEDIRSSGRNSPSAAS 618 Query: 554 TNA---QAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATP- 609 T++ +A + A P+ + R + + +Q ++ P Sbjct: 619 TSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPN 678 Query: 610 -----------SLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSP 658 S + + + K ++ ++S P PSP+ + S ++ S + + Sbjct: 679 SPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTS---PSIPSPQDNESDSDSSAQQQML- 734 Query: 659 LRGGEAGPDA--SPTVTTPTVT-----TPSLPAEVGSPHSTEVDESLSVSFEQVL-PPSA 710 +A P A +PT TP + TP LP +P +T V S + Q P A Sbjct: 735 ----QAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQA 790 Query: 711 PTSEAGLSLPLRGP--RARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSA 768 PT+ + + P +R SPH P P+P P Sbjct: 791 PTAPVPHTHIQQAPALHPQRPPSPHP-----------------PPHPSPHPP-------- 825 Query: 769 RSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPL 828 Q G G P++ S + P L P PG + + +H P P Sbjct: 826 -LQPLTGSAGQ----PSAPSHAQPPLHGQGP----PGP----HSLQAGPLLQHPGPPQPF 872 Query: 829 KVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKG 888 +PP + P P T+ Q + P + P + K Sbjct: 873 GLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPP 932 Query: 889 LAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVY 948 + P A P G +P S ++ P P S S+ SA PP + Sbjct: 933 TTPIPQLPAP-QAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLM 991 Query: 949 LDLAYLPS 956 LPS Sbjct: 992 PQSQPLPS 999 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 65.1 bits (157), Expect = 3e-10 Identities = 118/519 (22%), Positives = 171/519 (32%), Gaps = 73/519 (14%) Query: 460 TPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQER---------PGVARKEPARAE 510 +P+ P R E K S S R + P P E+ P V KEP+ E Sbjct: 181 SPRRRSSPVRRERKRS---HSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQE 237 Query: 511 APRKTE----------KEAKTPRELKKDPKPSVS-RTQPREVRRAASSVPNLKKTNAQAA 559 A ++ E K P K K +T+PR R+ S ++ + Sbjct: 238 ATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTR 297 Query: 560 PKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAG 619 P+ R+ S S S P PR PS R +PP P + +P + Sbjct: 298 PR-RRHRSRSRSYSPRRRPSPRRRPSPR--RRTPPRRMPPPPRHRRSRSP------VRRR 348 Query: 620 EEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVT----TP 675 + L ++SS R+ SP P + +R S P + P ASP +P Sbjct: 349 RRSSASLSGSSSSSSSSRSRSP-----PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSP 403 Query: 676 TVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSL---PLRGPRARR---S 729 T P +P + VS T G P P+ R+ S Sbjct: 404 PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELS 463 Query: 730 ASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSA------RSQERAGGLGAEETP 783 S D + + + R+ +S S + SS+ RS + G +G Sbjct: 464 ESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRH 523 Query: 784 PTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLK---VPPPLPDPSSI 840 S S S P ++T G R P P P + P P P P Sbjct: 524 SPSRSAS-------------PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRR- 569 Query: 841 CMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLS 900 PP R R R P R S + +P K + + R S Sbjct: 570 ---RRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRAS 626 Query: 901 ARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVS 939 P + +P ++ S+P T R PS S+ R G S Sbjct: 627 PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSS 665 Score = 61.6 bits (148), Expect = 4e-09 Identities = 128/587 (21%), Positives = 196/587 (33%), Gaps = 108/587 (18%) Query: 456 EPVVTPQDL---EGPGRAESKESVGSRDSSKREGLLATHPR-PGQERPGVARKEPARAEA 511 EP+ P++ + + + KE R S+ + T R P RP + +R+ + Sbjct: 251 EPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYS 310 Query: 512 PRK--------TEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNL------------ 551 PR+ + + PR + P+ SR+ R RR+++S+ Sbjct: 311 PRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP 370 Query: 552 -KKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPA-------- 602 KK + + PRK S S PP SPP A+PP SP Sbjct: 371 PKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPP------ATPPPKTRHSPTPQQSNRTR 424 Query: 603 -SQLVATPSLELG-------------PIPAGEEKALELP----------LAASSIPRPRT 638 S++ +P G P PA + + +EL AA S+ + R Sbjct: 425 KSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQ 484 Query: 639 -------PSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHS 691 S +S S + ER S ++ GE G + + +P + SP Sbjct: 485 YRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRG 544 Query: 692 TEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEH---R 748 + P PT P PR RR+ +P P R Sbjct: 545 RR----------RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPR 594 Query: 749 KAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTS--VSESLPTLSDSDPVPLAPGA 806 + P SP S A +PP VS S P S PV Sbjct: 595 RYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 654 Query: 807 ADSDEDTEGFGVPR-----HDPLPDPLKVPPPLPDPSSICMVDPEML--PPKTARQTENV 859 + S + +G R P P+ P P P P + + ++ ++ Sbjct: 655 SLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSP 714 Query: 860 SRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSS 919 S + +P+ R SR PK AA+ + +SR +S EP+ K K Sbjct: 715 SPSTRPIRRV-SRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAK--------KPP 765 Query: 920 TPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSSAHLVDEE 966 P + + S S + P V KSP PS S D+E Sbjct: 766 APPSPVQSQSPSTNWSPAVPVKKAKSPT-------PSPSPPRNSDQE 805 Score = 61.2 bits (147), Expect = 5e-09 Identities = 80/348 (22%), Positives = 116/348 (33%), Gaps = 33/348 (9%) Query: 471 ESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAP--RKTEKEAKTPRELKKD 528 +S GS SS+ E +H + G E R P+R+ +P RK +KE ++ Sbjct: 491 QSSSDSGSSSSSEDERPKRSHVKNG-EVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRS 549 Query: 529 PKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRC 588 P P +R RR+ S P ++ P R+ PS P P R Sbjct: 550 PSPPPTRR-----RRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY 604 Query: 589 GEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPA 648 + PP SP P P P + + P P+ R+ RSP+ Sbjct: 605 SPSPPPKRRTASPPPP----PKRRASPSPPPKRRVSHSPP-----PKQRSSPVTKRRSPS 655 Query: 649 EGSE-RLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLP 707 S+ R SP R P P P SP S S Q Sbjct: 656 LSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPS 715 Query: 708 PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSS 767 PS P + +++ASP + VS P A P +P S S Sbjct: 716 PSTRPIRRVSRTP-EPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQS- 773 Query: 768 ARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEG 815 ++P T+ S ++P P P +SD++ G Sbjct: 774 -------------QSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGG 808 Score = 39.7 bits (91), Expect = 0.015 Identities = 41/161 (25%), Positives = 61/161 (37%), Gaps = 34/161 (21%) Query: 455 REPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRP--------------GQERPG 500 R P ++ + +G + S S +KR + PRP G Sbjct: 652 RSPSLSSKHRKGSSPSRSTREARSPQPNKRH---SPSPRPRAPQTSSSPPPVRRGASSSP 708 Query: 501 VARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASS-------VPNLKK 553 R+ P+ + P + P+++KK PS P+ VRR +SS P KK Sbjct: 709 QRRQSPSPSTRPIRRVSRTPEPKKIKKAASPS-----PQSVRRVSSSRSVSGSPEPAAKK 763 Query: 554 TNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPP 594 A +P ++PST+ S PV PS SPP Sbjct: 764 PPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPS-----PSPP 799 >gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo sapiens] Length = 1393 Score = 64.3 bits (155), Expect = 6e-10 Identities = 120/527 (22%), Positives = 187/527 (35%), Gaps = 87/527 (16%) Query: 467 PGRAESKESVGSRDSSKREGLLATHPRPGQ--ERPGVARKE--PARAEAPRKTEKEAK-- 520 P AE E+ G R E ++ P + ER +A + P+ AE E+ A Sbjct: 575 PSLAEPTEN-GQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANEN 633 Query: 521 -TP--------RELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPK------PRKA 565 TP RE+ + K ++ +P E R + N K T++ A P P Sbjct: 634 TTPSPAGPTENREMTANEKTTLFPAEPTENRERTA---NEKTTSSPAEPTENGQRTPFAN 690 Query: 566 PSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALE 625 T+ S P +G R+P + SP P T + + P PA + E Sbjct: 691 EKTTSSSAEPTEHGERTPLANENTTLSP-----AEPTENRERTANEKTTPFPAEPTENRE 745 Query: 626 LPLAASSIPRPRTPSPESHRSPAEGSERLS--LSPLRGGEAGPDASPTVTTPTVTTPSLP 683 ++ P P P+ R+P + P G+ P A+ TT + P+ Sbjct: 746 RTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEK-TTSSSAEPTEH 804 Query: 684 AE---------VGSPHSTEVDESLSVSFEQVLPPSAPT-------SEAGLSLPLRGPRAR 727 AE SP + + + + P+ PT +E P R Sbjct: 805 AERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENR 864 Query: 728 RSASPHDVDLCLVSPCEFEHRKAVPMAP-----APASPGSSNDSSARSQERAGGLGAEET 782 + + L P E H + P+A +PA P + + + + E+ AE Sbjct: 865 EWTANENTTLSPAEPTE--HEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAE-- 920 Query: 783 PPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICM 842 PT E P ++ P A+ E G + P P K P Sbjct: 921 -PTEHGERTPLANEIT----TPSRAEPTE--HGERIANEKATPSPAK-----PTEHGETT 968 Query: 843 VDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSAR 902 V+ E P +A TEN RT PLA N+ + ++T G+R + + Sbjct: 969 VN-EDTTPSSAEPTENGERT--PLANENTTTSPTESTE----------HGERTANEKTTP 1015 Query: 903 S--EPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPV 947 S EP+E G R P + + + P A P+ P + SPV Sbjct: 1016 SPAEPTEHGERTPSANEKTIPSPAK--PTEHEEMTPSANENTTPSPV 1060 Score = 57.4 bits (137), Expect = 7e-08 Identities = 119/505 (23%), Positives = 177/505 (35%), Gaps = 81/505 (16%) Query: 492 PRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNL 551 P +ER + P+ AE TE +TP + K + S +P E + N Sbjct: 540 PTENRERTANEKTTPSPAEP---TENGDRTPLA---NEKTTPSLAEPTE-NGQRTPFANE 592 Query: 552 KKTNAQAAPKPRKAPSTSHSGFPPVAN-----GPRSPPSLR---CGEASPPSAACGSPAS 603 K T++ A P T H P+AN P P R E + PS A + Sbjct: 593 KTTSSSAEP-------TEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENR 645 Query: 604 QLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLS--PLRG 661 ++ A L P E + E + P P+ R+P + S S P Sbjct: 646 EMTANEKTTLFPAEPTENR--ERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEH 703 Query: 662 GEAGPDASPTVTT----PTVTTPSLPAEVGSPHSTEVDESLS-VSFEQVLPPSAPTSEAG 716 GE P A+ T PT E +P E E+ + E P A +E G Sbjct: 704 GERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENG 763 Query: 717 LSLPLRG---------PRARRSASPHDVDLCLVSPCE-FEHRKAVPMA-----PAPASPG 761 PL P +P + S E EH + P+A +PA P Sbjct: 764 DRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPT 823 Query: 762 SSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRH 821 + + +A E+ AE PT ES + P P P E + Sbjct: 824 ENRERTAN--EKTTQFPAE---PTENRESTAN-EKTTPFPAEPTENREWTANENTTLSPA 877 Query: 822 DPLPDPLKVPPPLPDPSSICMVDP-----------EMLPPKTARQTENVSRTRKPLARP- 869 +P ++ P + +++ +P E P +A TE+ RT PLA Sbjct: 878 EPTEHE-EMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERT--PLANEI 934 Query: 870 -----------NSRAAAPKATPVAAAKTK-GLAGGDRASRPLSARSEPSEKGGRAPLSRK 917 R A KATP A T+ G + + P SA EP+E G R PL+ + Sbjct: 935 TTPSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSA--EPTENGERTPLANE 992 Query: 918 SSTPKTATRGPSGSASSRPGVSATP 942 ++T G ++ + +P Sbjct: 993 NTTTSPTESTEHGERTANEKTTPSP 1017 Score = 57.0 bits (136), Expect = 9e-08 Identities = 112/508 (22%), Positives = 174/508 (34%), Gaps = 56/508 (11%) Query: 460 TPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQ--ERPGVARKEPARAEAPRKTEK 517 T + P AE E+ G R E ++ P + ER +A + + A TE Sbjct: 486 TANEKTTPSPAEPTEN-GQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA-EPTEN 543 Query: 518 EAKTPRELKKDPKPSV-SRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPV 576 +T E K P P+ + R + P+L + P T+ S P Sbjct: 544 RERTANE-KTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPT 602 Query: 577 ANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRP 636 + R+P + E + PS A P T + P PAG + E+ + P Sbjct: 603 EHEERTPLA---NENTTPSPA--EPTENRERTANENTTPSPAGPTENREMTANEKTTLFP 657 Query: 637 RTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDE 696 P+ R+ E + P G+ P A+ T+ S TE E Sbjct: 658 AEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTS------------SSAEPTEHGE 705 Query: 697 SLSVSFEQV-LPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVP-MA 754 ++ E L P+ PT R A +P + P E R A Sbjct: 706 RTPLANENTTLSPAEPTEN-------RERTANEKTTPFPAE-----PTENRERTANENTT 753 Query: 755 PAPASPGSSNDSSARSQERAGGLGAEETPP---TSVSESLPTLSDSDPVPLAPGAADSDE 811 P+PA P + D + + E+ AE T T + T S ++P A ++E Sbjct: 754 PSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANE 813 Query: 812 DTEGFGVP----RHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRT--RKP 865 +T R + P P + + E P A TEN T Sbjct: 814 NTTSSPAEPTENRERTANEKTTQFPAEPTENRESTAN-EKTTPFPAEPTENREWTANENT 872 Query: 866 LARPNSRAAAPKATPVAAAKT-----KGLAGGDRA----SRPLSARSEPSEKGGRAPLSR 916 P + TP+A KT + G+R + + +EP+E G R PL+ Sbjct: 873 TLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLAN 932 Query: 917 KSSTPKTATRGPSGSASSRPGVSATPPK 944 + +TP A G + + +P K Sbjct: 933 EITTPSRAEPTEHGERIANEKATPSPAK 960 Score = 55.5 bits (132), Expect = 3e-07 Identities = 109/471 (23%), Positives = 163/471 (34%), Gaps = 57/471 (12%) Query: 460 TPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTEKEA 519 T + P AE E+ R +++ L P +ER P A E A Sbjct: 292 TANENNTPSPAEPTEN-RERTANENTTLSPAEPIENRERTANENTAPFPAGPTENREMTA 350 Query: 520 KTPREL-KKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVAN 578 L +P RT + + + A P A T H P AN Sbjct: 351 NENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFAN 410 Query: 579 GPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRT 638 + S E + P + TPS PA + E ++ P P Sbjct: 411 DKTTSSSAESTEHGERT-----PLANENTTPS------PAEPTENRERTANENTTPSPAG 459 Query: 639 PSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESL 698 P+ E+ + A +E+ +LSP+ P + T TTPS PAE TE + Sbjct: 460 PT-ENRETTA--NEKTTLSPVE-----PTENRETTANEKTTPS-PAE-----PTENGQRT 505 Query: 699 SVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKA-VPMAPAP 757 + E+ SA +E G PL A + +P + P E R A P+P Sbjct: 506 PFANEKTTSSSAEPTEHGERTPL----ANENTTPSPAE-----PTENRERTANEKTTPSP 556 Query: 758 ASPGSSNDSSARSQERAGGLGAEET---PPTSVSESLPTLSDSDPV---PLAPGAADSDE 811 A P + D + + E+ AE T T + T S ++P P A ++ Sbjct: 557 AEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTT 616 Query: 812 DTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRT--RKPLARP 869 + + + P P + M E A TEN RT K + P Sbjct: 617 PSPAEPTENRERTANENTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSP 676 Query: 870 NSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSST 920 + TP A KT S+ +EP+E G R PL+ +++T Sbjct: 677 AEPTENGQRTPFANEKT------------TSSSAEPTEHGERTPLANENTT 715 Score = 45.8 bits (107), Expect = 2e-04 Identities = 64/281 (22%), Positives = 100/281 (35%), Gaps = 21/281 (7%) Query: 652 ERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAP 711 E +S + L A P T TPS PAE +E+ ++S + + Sbjct: 271 ETISANELTQSLAEPTEHGGRTANENNTPS-PAEPTENRERTANENTTLSPAEPIENRER 329 Query: 712 TSEAGLSLPLRGPRARRSASPHD-VDLCLVSPCEFEHRKAVP-MAPAPASPGSSNDSSAR 769 T+ + GP R + ++ L P E R A P+PA P + +A Sbjct: 330 TANENTAPFPAGPTENREMTANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTAN 389 Query: 770 SQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLK 829 PT E P +D +A+S E E + + P P + Sbjct: 390 ENTTPS-----PAEPTEHGERTPFANDKT----TSSSAESTEHGERTPLANENTTPSPAE 440 Query: 830 VPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSR--AAAPKATPVAAAKTK 887 ++ P + T N T P+ +R A K TP A T+ Sbjct: 441 PTENRERTANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTE 500 Query: 888 GLAGGDRA----SRPLSARSEPSEKGGRAPLSRKSSTPKTA 924 G R + S+ +EP+E G R PL+ +++TP A Sbjct: 501 N---GQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 538 Score = 30.8 bits (68), Expect = 7.1 Identities = 26/101 (25%), Positives = 44/101 (43%), Gaps = 11/101 (10%) Query: 849 PPKTARQTENVSRTRKPLARPNS---RAAAPKATPVAAAKTKGLAGGDRA----SRPLSA 901 P + +T N + T P A P R A TP A T+ G+R + S+ Sbjct: 361 PTEHGERTANENTTPSP-AEPTEHGERTANENTTPSPAEPTEH---GERTPFANDKTTSS 416 Query: 902 RSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATP 942 +E +E G R PL+ +++TP A + ++ + +P Sbjct: 417 SAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSP 457 >gi|157074225 nuclear pore complex interacting protein-like 3 [Homo sapiens] Length = 678 Score = 64.3 bits (155), Expect = 6e-10 Identities = 89/355 (25%), Positives = 124/355 (34%), Gaps = 48/355 (13%) Query: 400 PPSAGAERTLASVCALLVWHPAG------PGEKVVRVLFPGC-----TPPACLLDGLVRL 448 PPSA C L P+ P E V+ L P TPP CLL L Sbjct: 275 PPSADDNLKTPPECVLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTPPECLLTPLPPS 334 Query: 449 --QHLRFLREPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQ-----ERPGV 501 +L+ E ++TP P A + D+ K HP P + P Sbjct: 335 ADDNLKTPPECLLTPL----PPSALPSAPPSADDNLKTRAECLLHPLPPSADDNLKTPSE 390 Query: 502 ARKEPARAEAPRKTEKEAKTPRELKKDPKP-----SVSRTQPREVRRAASSVPNLKKTNA 556 + P AP + KTP E + P P ++ R++ S P N Sbjct: 391 RQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNI 450 Query: 557 QAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLEL-GP 615 + + + P PP A+ PS R PPSA A + TP+ L GP Sbjct: 451 KTPAERLRGP------LPPSADDNLKTPSERQLTPLPPSAP--PSADDNIKTPAERLRGP 502 Query: 616 IPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTP 675 +P + L+ P P P + P + + +ERL G P A + TP Sbjct: 503 LPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLR------GPLPPSADDNLKTP 556 Query: 676 TVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSA 730 + T AE P + + E PP G P R P+ RR+A Sbjct: 557 PLATQE--AEAEKPRKPKRQRAA----EMEPPPEPKRRRVGDVEPSRKPKRRRAA 605 Score = 55.1 bits (131), Expect = 3e-07 Identities = 103/422 (24%), Positives = 151/422 (35%), Gaps = 89/422 (21%) Query: 512 PRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHS 571 P + KTP E P P P + A S + KT A+ P Sbjct: 332 PPSADDNLKTPPECLLTPLP------PSALPSAPPSADDNLKTRAECLLHP--------- 376 Query: 572 GFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLEL-GPIPAGEEKALELPLAA 630 PP A+ PS R PPSA A + TP+ L GP+P + L+ P Sbjct: 377 -LPPSADDNLKTPSERQLTPLPPSAP--PSADDNIKTPAERLRGPLPPSADDNLKTPSER 433 Query: 631 SSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPH 690 P P + P + + +ERL G P A + TP+ Sbjct: 434 QLTPLPPSAPPSADDNIKTPAERLR------GPLPPSADDNLKTPS-------------- 473 Query: 691 STEVDESLSVSFEQVLPPSAPTS-EAGLSLP---LRGPRARRSASPHDVDLCLVSPCEFE 746 + L+ LPPSAP S + + P LRGP P D L +P E Sbjct: 474 ----ERQLT-----PLPPSAPPSADDNIKTPAERLRGP------LPPSADDNLKTPSE-- 516 Query: 747 HRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGA 806 R+ P+ P++P S++D+ ER G P S ++L T PLA Sbjct: 517 -RQLTPL--PPSAPPSADDNIKTPAERLRG-----PLPPSADDNLKT------PPLATQE 562 Query: 807 ADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPP-KTARQTENVSRTRK- 864 A++++ + P+ + PPP P + V+P P + A E S K Sbjct: 563 AEAEKPRK----PKRQRAAE--MEPPPEPKRRRVGDVEPSRKPKRRRAADVEPSSPEPKR 616 Query: 865 -------PLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRK 917 P +P R AA K + + + + +P R+ E P R+ Sbjct: 617 RRVGDVEPSRKPKRRRAADVEPSSPEPKRRRVGDVEPSRKPKRRRAADVEPSLPEPKRRR 676 Query: 918 SS 919 S Sbjct: 677 LS 678 Score = 45.4 bits (106), Expect = 3e-04 Identities = 78/286 (27%), Positives = 102/286 (35%), Gaps = 40/286 (13%) Query: 666 PDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPR 725 P A + TP P V +P D++L E VL P P+++ L P P Sbjct: 276 PSADDNLKTP-------PECVLTPLPPSADDNLKTPPECVLTPLPPSADDNLKTP---PE 325 Query: 726 ARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPT 785 + P D L +P E P A A P + ++ R++ L P Sbjct: 326 CLLTPLPPSADDNLKTPPECLLTPLPPSALPSAPPSADDNLKTRAECLLHPL------PP 379 Query: 786 SVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPR-HDPLP----DPLKVP-----PPLP 835 S ++L T S+ PL P A S +D R PLP D LK P PLP Sbjct: 380 SADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLP 439 Query: 836 DPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAA---PKATPVAAAKTKGLAGG 892 PS+ D + P + L P+ R P A P A K A Sbjct: 440 -PSAPPSADDNIKTPAERLRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAER 498 Query: 893 DRASRPLSARSE---PSEK-----GGRAPLSRKSS--TPKTATRGP 928 R P SA PSE+ AP S + TP RGP Sbjct: 499 LRGPLPPSADDNLKTPSERQLTPLPPSAPPSADDNIKTPAERLRGP 544 >gi|167736355 mucin 4 isoform a [Homo sapiens] Length = 5284 Score = 63.5 bits (153), Expect = 1e-09 Identities = 104/461 (22%), Positives = 156/461 (33%), Gaps = 52/461 (11%) Query: 506 PARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKP--- 562 P +P TP + S P V +S+ + A P P Sbjct: 2896 PLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSA------STGHATPLPVTD 2949 Query: 563 RKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEK 622 + ST H+ PV S S+ G+ +P S AS TP A + Sbjct: 2950 TSSASTGHATPLPVT----SLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQ 3005 Query: 623 ALELPLAASS-------IPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGP-------DA 668 A LP+ ++S P P T + + A SLS + G+ P A Sbjct: 3006 ATALPVTSTSSASTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSA 3065 Query: 669 SPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARR 728 S TP + T + A G V SVS P LP+ P + Sbjct: 3066 STGHATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTP-----------LPVTSPSS-- 3112 Query: 729 SASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVS 788 +++ H L + + S + D+++ +T P V+ Sbjct: 3113 ASTGHATSLPVTDTSSASTGDTTSLPVTDTSSAYTGDTTSLPVTDTSSSSTGDTTPLLVT 3172 Query: 789 ESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKV----PPPLPDPSSICMVD 844 E+ ++S PL D+ + G P H P P P+ D SS+ Sbjct: 3173 ET-SSVSTGHATPLL--VTDASSASTGHATPLHVTSPSSASTGDTTPVPVTDTSSVSTGH 3229 Query: 845 PEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSE 904 LP TR P+ +S A+ +ATP+ T ++ GD P+++ S Sbjct: 3230 ATPLPVTGLSSASTGDTTRLPVTDISS-ASTGQATPLPVTNTSSVSTGDTMPLPVTSPSS 3288 Query: 905 PSEKGGRAPL---SRKSSTPKTATRGPSGSASSRPGVSATP 942 S G PL S S++ AT P S SS TP Sbjct: 3289 AS-TGHATPLPVTSTSSASTGHATPVPVTSTSSASTGHTTP 3328 Score = 60.5 bits (145), Expect = 8e-09 Identities = 95/384 (24%), Positives = 138/384 (35%), Gaps = 27/384 (7%) Query: 582 SPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLA-ASSI------P 634 SP S G A+P S AS P P A LP+ ASS+ P Sbjct: 1301 SPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHTTP 1360 Query: 635 RPRTPSPESHRSPAEGSERLSLSPLRGGEAGP-------DASPTVTTPTVTTPSLPAEVG 687 T + + A SLS + G+ P AS TP + T + A G Sbjct: 1361 LHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDTSSASTG 1420 Query: 688 SPHSTEVDESLSVSFEQV--LPPSAPTSEA-GLSLPLRGPRARRSASPHDVDLCLVSPCE 744 V ++ SVS + LP + P++ + G + PL +++ L + Sbjct: 1421 HATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLVTDTSS 1480 Query: 745 FEHRKAVPM---APAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVP 801 P+ + + AS G S A A P TS+S + + D+ P+P Sbjct: 1481 VSTGDTTPLPVTSTSSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSA--STGDTMPLP 1538 Query: 802 LAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSR 861 + ++ S DT V + P P+ PSS LP Sbjct: 1539 VTSPSSASTGDTTPLPVTDASSVSTGHTTPLPVTSPSSASTGHTTPLPVTDTSSASKGDT 1598 Query: 862 TRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPL---SRKS 918 T P+ P+S A+ TP+ T + GD P++ S S G PL S S Sbjct: 1599 TPLPVTSPSS-ASTGHTTPLPVTDTSSASTGDTTPLPVTNASSLS-TGHATPLHVTSPSS 1656 Query: 919 STPKTATRGPSGSASSRPGVSATP 942 ++ AT P S SS ATP Sbjct: 1657 ASTGHATPLPVTSTSSASTGHATP 1680 Score = 59.7 bits (143), Expect = 1e-08 Identities = 108/456 (23%), Positives = 163/456 (35%), Gaps = 42/456 (9%) Query: 506 PARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPN----LKKTNAQAAPK 561 P +P TP + S P V +S+ + L T+ +A Sbjct: 1648 PLHVTSPSSASTGHATPLPVTSTSSASTGHATPLPVTGLSSATTDDTTRLPVTDVSSAST 1707 Query: 562 PRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEE 621 + P PV S S+ G+ +P S AS A+P L A Sbjct: 1708 GQATPL-------PVT----SLSSVSTGDTTPLPVTSPSSASTGHASPLLVTDASSASTG 1756 Query: 622 KALELPLA-ASSIPRPR-TPSPESHRSPA--EGSERLSLSPLRGGEAG-----PDASPTV 672 +A LP+ SS+ TP P + S A + + RL ++ + G P SP+ Sbjct: 1757 QATPLPVTDTSSVSTAHATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSS 1816 Query: 673 TTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASP 732 + TTP LP S ST SL V+ PS+ +S SLP+ A ++ Sbjct: 1817 ASTGDTTP-LPVTDASSASTGDTTSLPVTI-----PSSASSGHTTSLPVTD--ASSVSTG 1868 Query: 733 HDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLG---AEETPPTSVSE 789 H L + P+ + S+ D++ A + A P TS+S Sbjct: 1869 HATSLLVTDASSVSTGDTTPLPVTDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSS 1928 Query: 790 SLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLP 849 + + D+ P+P+ ++ S T V +P P+ D SS+ LP Sbjct: 1929 A--STGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSLPVTDASSVSTGHATPLP 1986 Query: 850 PKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKG 909 A T P+ S + +ATP+ + GD P++ S S G Sbjct: 1987 VTDASSVSTGHATPLPVT-DTSSVSTGQATPLPVTSLSSASTGDTTPLPVTDTSSAS-TG 2044 Query: 910 GRAPL---SRKSSTPKTATRGPSGSASSRPGVSATP 942 PL S S + T P S SS ATP Sbjct: 2045 QDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATP 2080 Score = 59.7 bits (143), Expect = 1e-08 Identities = 108/456 (23%), Positives = 159/456 (34%), Gaps = 40/456 (8%) Query: 521 TPRELKKDPKPSVSRTQPREVRRAAS----SVPNLKKTNAQ------AAPKPRKAPSTSH 570 TP + S T P V A+S +L T+A A P PS++ Sbjct: 2655 TPLHVTSPSSASTGHTTPLPVTDASSVSTGHATSLPVTDASSVFTGHATSLPVTIPSSAS 2714 Query: 571 SGFP-PVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLA 629 SG P+ S S + P + A P + + G L L Sbjct: 2715 SGHTTPLPVTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSL 2774 Query: 630 ASSIPRPRTPSPESHRSPAEGSERL-----SLSPLRGGEAGP-DASPTVTTPTVTTPSLP 683 +S TP P + S A + SLS + G+ P + T + T SLP Sbjct: 2775 SSVSTGDTTPLPVTDTSSASTGQATPLPVTSLSSVSTGDTTPLPVTDTSSASTGHATSLP 2834 Query: 684 AEVGSPHST-------EVDESLSVSFEQVLPPSAPTSEAGL----SLPLRGPRARRSASP 732 S ST + D S + + L P TS A + SLP+ + ++ Sbjct: 2835 VTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASIGHATSLPVTDTSS--ISTG 2892 Query: 733 HDVDLCLVSPCEFEHRKAVPMA---PAPASPGSSNDSSARSQERAGGLGAEETPPTSVSE 789 H L + SP A P+ + AS G +N S A A P T S Sbjct: 2893 HATPLHVTSPSSASTGHATPLPVTDTSSASTGHANPLHVTSPSSASTGHATPLPVTDTSS 2952 Query: 790 SLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLP 849 + + + P+P+ ++ S DT V P P+ D SS LP Sbjct: 2953 A--STGHATPLPVTSLSSVSTGDTTPLPVTSPSSASTGHTTPLPVTDTSSASTGQATALP 3010 Query: 850 PKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKG 909 + T P+ +S A+ +ATP+ ++ GD P+++ S S G Sbjct: 3011 VTSTSSASTGDTTPLPVTDTSS-ASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAS-TG 3068 Query: 910 GRAPL---SRKSSTPKTATRGPSGSASSRPGVSATP 942 PL S++ AT P S SS TP Sbjct: 3069 HATPLLVTDASSASTGQATPLPVTSLSSVSTGDTTP 3104 Score = 54.3 bits (129), Expect = 6e-07 Identities = 108/440 (24%), Positives = 152/440 (34%), Gaps = 47/440 (10%) Query: 532 SVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFP---PVANGPRSPPSLRC 588 S T P V A+S+ + QA P P + S+ +G PV SP S Sbjct: 1146 STGHTTPLHVTDASSA------STGQATPLPVTSLSSVSTGDTTPLPVT----SPSSAST 1195 Query: 589 GEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRP--RTPSPESHRS 646 G A+P S AS ATP + A LP+ S TP P + S Sbjct: 1196 GHATPLLVTDTSSASTGHATPLPVTDASSVSTDHATSLPVTIPSAASTGHTTPLPVTDTS 1255 Query: 647 PAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVL 706 A + SL + T + T T LP S ST L V+ Sbjct: 1256 SASTGQATSLL----------VTDTSSVSTGDTTPLPVTSTSSASTGHVTPLHVT----S 1301 Query: 707 PPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDS 766 P SA T G + PL +++ + L + SP P+ AS S+ + Sbjct: 1302 PSSAST---GHATPLPVTSLSSASTGDTMPLPVTSPSSASTGDTTPLPVTDASSVSTGHT 1358 Query: 767 SARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPL---APGAADSDEDTEGFGVPRHDP 823 + A + P V+ SL ++S D PL +P +A + T V Sbjct: 1359 TPLHVTDASSASTGQATPLPVT-SLSSVSTGDTTPLPVTSPSSASTGHATP-LLVTDTSS 1416 Query: 824 LPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAA 883 P P+ D SS+ D P T + T S A+ +AT + Sbjct: 1417 ASTGHATPLPVTDASSV-STDHATSLPVTIPSAASTGHTTPLPVTDTSSASTGQATSLLV 1475 Query: 884 AKTKGLAGGDRASRPLSARSEPSEKGGRAPL--------SRKSSTPKTATRGPSGSASSR 935 T ++ GD P+++ S S G PL S +TP T S S Sbjct: 1476 TDTSSVSTGDTTPLPVTSTSSAS-TGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDT 1534 Query: 936 PGVSATPPKSPVYLDLAYLP 955 + T P S D LP Sbjct: 1535 MPLPVTSPSSASTGDTTPLP 1554 Score = 52.8 bits (125), Expect = 2e-06 Identities = 96/455 (21%), Positives = 156/455 (34%), Gaps = 51/455 (11%) Query: 506 PARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKP--- 562 P +P TP + S T P V +S+ + A P P Sbjct: 3728 PLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSA------STRHATPLPVTD 3781 Query: 563 RKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEK 622 + ST + PV + S G A+P S AS TP +P + Sbjct: 3782 TSSASTDDTTRLPVTD----VSSASTGHATPLPVTSTSSASTGDTTP------LPVTDTS 3831 Query: 623 ALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTP-S 681 ++ A S R+ + H +P ++ S+S G A P P +T +V+T + Sbjct: 3832 SVSTGHATSLPVTSRSSASTGHATPLPVTDTSSVST---GHATP--LPVTSTSSVSTGHA 3886 Query: 682 LPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVS 741 P V SP S + V S ++ G + PL A ++ H L + S Sbjct: 3887 TPLPVTSPSSASTGHATPVPVT-----STSSASTGDTTPLPVTNASSLSTGHATPLHVTS 3941 Query: 742 PCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSES----------L 791 P + AS S+ ++ + +T P V+++ L Sbjct: 3942 PSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSVSTGDTTPLPVTDTSSASTGQATPL 4001 Query: 792 PTLS-------DSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVD 844 P S D+ P+P+ ++ S T V + P P+ SS D Sbjct: 4002 PVTSLSSVSTGDTTPLPVTIPSSASSGHTTSLPVTDASSVSTGHGTPLPVTSTSSASTGD 4061 Query: 845 PEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSE 904 LP T P+ S A+ ATP+ ++ G +S+ + Sbjct: 4062 TTPLPVTDTSSASTGHATPLPVT-DTSSASTGHATPLPVTSLSSVSTGHATPLAVSSATS 4120 Query: 905 PSEKGGRAPLSRKS---STPKTATRGPSGSASSRP 936 S +PL ++ +TP T G +A+S P Sbjct: 4121 ASTVSSDSPLKMETPGMTTPSLKTDGGRRTATSPP 4155 Score = 52.0 bits (123), Expect = 3e-06 Identities = 92/413 (22%), Positives = 145/413 (35%), Gaps = 27/413 (6%) Query: 567 STSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPS--LELGPIPAGEEKAL 624 ST H+ PV S S G+ +P S AS TP + +P G +L Sbjct: 1914 STGHATSLPVT----SLSSASTGDTTPLPVTSPSSASSGHTTPLPVTDASSVPTGHATSL 1969 Query: 625 ELPLAASSIPRPRTPSPESHRSPAEGSERLSL-----SPLRGGEAGP-------DASPTV 672 + A+S TP P + S L S + G+A P AS Sbjct: 1970 PVTDASSVSTGHATPLPVTDASSVSTGHATPLPVTDTSSVSTGQATPLPVTSLSSASTGD 2029 Query: 673 TTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQV--LPPSAPTSEA-GLSLPLRGPRARRS 729 TTP T + A G V SVS LP ++P+S + G + PL A Sbjct: 2030 TTPLPVTDTSSASTGQDTPLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLLVTDASSV 2089 Query: 730 ASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSE 789 ++ H L + A + AS S+ D++ +T P V++ Sbjct: 2090 STGHATSLLVTDASSVSTGHATALHVTDASSLSTGDTTPLPVTSPSSASTGDTTPLPVTD 2149 Query: 790 -SLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEML 848 S + + +P+ ++ S V P P+ D SS L Sbjct: 2150 TSSVSTGHATSLPVTDTSSASTGHATSLPVTDTSSASTGHATPLPVTDTSSASTGQATPL 2209 Query: 849 PPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEK 908 P T+ + + L S A+ +ATP+ + GD + PL S Sbjct: 2210 PV-TSPSSASTGHAIPLLVTDTSSASTGQATPLPVTSLSSASTGD--TTPLPVTDASSVS 2266 Query: 909 GGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSSAH 961 G A +S +T + + P ++T +P+++ A S S+ H Sbjct: 2267 TGHATSLPVTSLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDA--SSASTGH 2317 Score = 51.2 bits (121), Expect = 5e-06 Identities = 105/493 (21%), Positives = 170/493 (34%), Gaps = 43/493 (8%) Query: 469 RAESKESVGSRDSSKREGLLATHPRPGQERP---GVARKEPARAEAPRKTEKEAKTPREL 525 +AES E+ G +S+ + G P G + P+ +E + + + Sbjct: 775 QAESTEASGQTQTSEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFSSNP 834 Query: 526 KKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKP--RKAPSTSHSGFPPVANGPRSP 583 +D + S T+ + ++P + P S +G P + P SP Sbjct: 835 SRDSHTTQSTTELLSASASHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSP 894 Query: 584 PSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPES 643 ASP A S +Q T + + +A + S++P P PS S Sbjct: 895 ------SASPQETAAISRMAQTQRTRTSRGSDTISLASQATD---TFSTVP-PTPPSITS 944 Query: 644 HRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFE 703 + +E +LSP G+ A + TP T + A G V ++ SVS Sbjct: 945 TGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVTYASSASTGHTTPLHVTDASSVSTG 1004 Query: 704 QV--LPPSAPTS-EAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASP 760 LP ++P+S G + PL ++ H L + S F P P + Sbjct: 1005 HATPLPVTSPSSVSTGHTTPLPVTDTSSESTGHVTPLPVTS---FSSASTGDSTPLPVTD 1061 Query: 761 GSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPR 820 SS + TP S S + D+ P+P+ ++ S V Sbjct: 1062 TSSAST------------GHVTPLPVTSLSSASTGDTTPLPVTDTSSASTGHATSLPVTD 1109 Query: 821 HDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATP 880 + P P+ D SS L P T + + T S A+ +ATP Sbjct: 1110 TSSVSTGHTTPLPVTDTSSASTGHATSL-PVTDTSSVSTGHTTPLHVTDASSASTGQATP 1168 Query: 881 VAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPL--------SRKSSTPKTATRGPSGSA 932 + ++ GD P+++ S S G PL S +TP T S S Sbjct: 1169 LPVTSLSSVSTGDTTPLPVTSPSSAS-TGHATPLLVTDTSSASTGHATPLPVTDASSVST 1227 Query: 933 SSRPGVSATPPKS 945 + T P + Sbjct: 1228 DHATSLPVTIPSA 1240 Score = 51.2 bits (121), Expect = 5e-06 Identities = 103/478 (21%), Positives = 154/478 (32%), Gaps = 54/478 (11%) Query: 506 PARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKP--- 562 P +P TP + S T P V +S+ + P P Sbjct: 1504 PLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLPVTSPSSA------STGDTTPLPVTD 1557 Query: 563 RKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEK 622 + ST H+ PV SP S G +P S AS+ TP P A Sbjct: 1558 ASSVSTGHTTPLPVT----SPSSASTGHTTPLPVTDTSSASKGDTTPLPVTSPSSASTGH 1613 Query: 623 ALELPLA--ASSIPRPRTPSPESHRSPAEGSERLSL---SPLRGGEAGPDASPTVTTPTV 677 LP+ +S+ TP P ++ S L SP P +T + Sbjct: 1614 TTPLPVTDTSSASTGDTTPLPVTNASSLSTGHATPLHVTSPSSASTGHATPLPVTSTSSA 1673 Query: 678 TTP-SLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVD 736 +T + P V S D++ + V ++ G + PL ++ Sbjct: 1674 STGHATPLPVTGLSSATTDDTTRLPVTDV-----SSASTGQATPLPVTSLSSVSTGDTTP 1728 Query: 737 LCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSD 796 L + SP A P+ AS S+ + TP S + + Sbjct: 1729 LPVTSPSSASTGHASPLLVTDASSASTGQA---------------TPLPVTDTSSVSTAH 1773 Query: 797 SDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQT 856 + P+P+ ++ S +DT V +P P+ PSS D LP A Sbjct: 1774 ATPLPVTGLSSASTDDTTRLPVTDVSSASTGQAIPLPVTSPSSASTGDTTPLPVTDASSA 1833 Query: 857 ENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPL-- 914 T P+ P+S A++ T + ++ G S ++ S S G PL Sbjct: 1834 STGDTTSLPVTIPSS-ASSGHTTSLPVTDASSVSTGHATSLLVTDASSVS-TGDTTPLPV 1891 Query: 915 ------SRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLP-----SGSSAH 961 S +TP T S S + T S D LP S SS H Sbjct: 1892 TDTNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGH 1949 Score = 50.4 bits (119), Expect = 9e-06 Identities = 112/484 (23%), Positives = 163/484 (33%), Gaps = 60/484 (12%) Query: 506 PARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASS----VPNLKKTNAQAAPK 561 P P + TP + S P V +S+ V L T+ +A Sbjct: 3568 PLPVTIPSSSSSGHTTPLPVTSTSSVSTGHVTPLHVTSPSSASTGHVTPLPVTSTSSAST 3627 Query: 562 PRKAP---------STSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPS-- 610 P ST H+ PV + S G+ +P S AS ATP Sbjct: 3628 GHATPLLVTDASSVSTGHATPLPVTDAS----SASTGDTTPLPVTDTSSASTGQATPLPV 3683 Query: 611 LELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSL-----SPLRGGEAG 665 L + G+ L + A+S+ TP P + S + + L S G A Sbjct: 3684 TSLSSVSTGDTTPLPVTDASSASTGHATPLPVTIPSSVSTGDTMPLPVTSPSSASTGHAT 3743 Query: 666 P-------DASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQV--LP----PSAPT 712 P AS TTP T + A V ++ S S + LP SA T Sbjct: 3744 PLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTDTSSASTDDTTRLPVTDVSSAST 3803 Query: 713 SEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPM------APAPASPGSSNDS 766 A LP+ + + + + S H ++P+ + A+P D+ Sbjct: 3804 GHA-TPLPVTSTSSASTGDTTPLPVTDTSSVSTGHATSLPVTSRSSASTGHATPLPVTDT 3862 Query: 767 SARSQERAGGLGAEETPPTSVSES--LPTLSDSD-------PVPLAPGAADSDEDTEGFG 817 S+ S A L T S + LP S S PVP+ ++ S DT Sbjct: 3863 SSVSTGHATPLPVTSTSSVSTGHATPLPVTSPSSASTGHATPVPVTSTSSASTGDTTPLP 3922 Query: 818 VPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPK 877 V L P + PSS D LP A T PL +S + Sbjct: 3923 VTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSS-VSTGD 3981 Query: 878 ATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPG 937 TP+ T + G P+++ S S G PL + P +A+ SG +S P Sbjct: 3982 TTPLPVTDTSSASTGQATPLPVTSLSSVS-TGDTTPL--PVTIPSSAS---SGHTTSLPV 4035 Query: 938 VSAT 941 A+ Sbjct: 4036 TDAS 4039 Score = 49.3 bits (116), Expect = 2e-05 Identities = 101/434 (23%), Positives = 148/434 (34%), Gaps = 60/434 (13%) Query: 521 TPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAP-KPRKAPSTSHSGFPPVANG 579 TP + S T P V +S + +A + P + ST H+ PV + Sbjct: 2127 TPLPVTSPSSASTGDTTPLPVTDTSS----VSTGHATSLPVTDTSSASTGHATSLPVTD- 2181 Query: 580 PRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLA--ASSIPRPR 637 S G A+P S AS ATP P A A+ L + +S+ Sbjct: 2182 ---TSSASTGHATPLPVTDTSSASTGQATPLPVTSPSSASTGHAIPLLVTDTSSASTGQA 2238 Query: 638 TPSPESHRSPAEGSERLSL-----SPLRGGEAGPDASPTVTTPTVTT-PSLPAEVGSPHS 691 TP P + S A + L S + G A + P + +V+T + P V SP S Sbjct: 2239 TPLPVTSLSSASTGDTTPLPVTDASSVSTGHA--TSLPVTSLSSVSTGDTTPLPVTSPSS 2296 Query: 692 TEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAV 751 + + A ++ G + PL +++ L + SP A Sbjct: 2297 ASTGHATPLHVTD-----ASSASTGHATPLPVTSLSSASTGDTTPLPVTSPSSASTGHAT 2351 Query: 752 PMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDE 811 P+ AS S+ D+ TP S S + + P+P+ ++ S Sbjct: 2352 PLHVTDASSVSTGDT---------------TPLPVTSSSSASSGHTTPLPVTDASSASTG 2396 Query: 812 DTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNS 871 DT P P+ D SS LP TR P+ +S Sbjct: 2397 DT----------------TPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVSS 2440 Query: 872 RAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPL---SRKSSTPKTATRGP 928 A+ ATP+ T + GD P + S S G PL S + TR P Sbjct: 2441 -ASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVS-TGHTTPLLVTDASSVSTGDTTRLP 2498 Query: 929 SGSASSRPGVSATP 942 S SS TP Sbjct: 2499 VTSPSSASTGHTTP 2512 Score = 47.8 bits (112), Expect = 6e-05 Identities = 96/416 (23%), Positives = 135/416 (32%), Gaps = 54/416 (12%) Query: 567 STSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALEL 626 ST H+ PV S S+ G+ +P S AS ATP A A L Sbjct: 2266 STGHATSLPVT----SLSSVSTGDTTPLPVTSPSSASTGHATPLHVTDASSASTGHATPL 2321 Query: 627 PLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEV 686 P+ + S +P SP+ S + +PL +A S TTP T S A Sbjct: 2322 PVTSLSSASTGDTTPLPVTSPSSASTGHA-TPLHVTDAS-SVSTGDTTPLPVTSSSSASS 2379 Query: 687 GSPHSTEVDESLSVSFEQVLP-PSAPTSEAGLS----LPLRGPRARRSASPHDVDLCLVS 741 G V ++ S S P P TS A LP+ G + + + + VS Sbjct: 2380 GHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHATHLPVTGLSSASTGDTTRLPVTNVS 2439 Query: 742 PCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSES----------L 791 H A P+ S S+ D++ + T P V+++ L Sbjct: 2440 SASTGH--ATPLPVTSTSSASTGDTTPLPGTDTSSVSTGHTTPLLVTDASSVSTGDTTRL 2497 Query: 792 PTLSDSD-------PVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVD 844 P S S P+P+ + S DT V L + PSS Sbjct: 2498 PVTSPSSASTGHTTPLPVTDTPSASTGDTTPLPVTNASSLSTRHATSLHVTSPSSASTGH 2557 Query: 845 PEMLP---------------PKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGL 889 LP P T+ + + T A+ +ATP+ T Sbjct: 2558 ATSLPVTDTSAASTGHATPLPVTSTSSASTGDTTPLPVTDTYSASTGQATPLPVTDTSSA 2617 Query: 890 AGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKS 945 + GD + PL S G A TP T S S + T P S Sbjct: 2618 STGD--TTPLPVTDTSSASTGHA-------TPLPVTNTSSVSTGHATPLHVTSPSS 2664 Score = 46.6 bits (109), Expect = 1e-04 Identities = 96/419 (22%), Positives = 143/419 (34%), Gaps = 27/419 (6%) Query: 554 TNAQAAPKPRKAPSTSHSGFP---PVANGPRSPPSLRCGEASPPSAACGSPASQLVATPS 610 + QA P P S+ +G PV SP S G A+P S AS ATP Sbjct: 3258 STGQATPLPVTNTSSVSTGDTMPLPVT----SPSSASTGHATPLPVTSTSSASTGHATPV 3313 Query: 611 LELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASP 670 A LP+ +S +P SP+ S +PL P ++ Sbjct: 3314 PVTSTSSASTGHTTPLPVTDTSSASTGDTTPLPVTSPSSASTG-HTTPLH--VTIPSSAS 3370 Query: 671 TVTTPTV-TTPSLPAEVGSPHSTEVDESLSVSFEQVLP---PSAPTSEAGLSLPLRGPRA 726 T T T+ T + A G V ++ SVS P S + G + PL A Sbjct: 3371 TGDTSTLPVTGASSASTGHATPLPVTDTSSVSTGHATPLPVTSLSSVSTGDTTPLPVTDA 3430 Query: 727 RRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTS 786 +++ L + S P+ AS S+ ++ +T Sbjct: 3431 SSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDTTRLP 3490 Query: 787 VSE-SLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDP 845 V++ S + + P+P+ ++ S DT V + P P+ D SS D Sbjct: 3491 VTDTSSASTGQATPLPVTSLSSVSTGDTTPLLVTDASSVSTGHATPLPVTDTSSASTGDT 3550 Query: 846 EMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEP 905 LP T P+ P+S +++ TP+ T ++ G PL S Sbjct: 3551 TRLPVTDTSSASTGQATPLPVTIPSS-SSSGHTTPLPVTSTSSVSTGH--VTPLHVTSPS 3607 Query: 906 SEKGGRA---PLSRKSS------TPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLP 955 S G P++ SS TP T S S + T S D LP Sbjct: 3608 SASTGHVTPLPVTSTSSASTGHATPLLVTDASSVSTGHATPLPVTDASSASTGDTTPLP 3666 Score = 41.6 bits (96), Expect = 0.004 Identities = 99/444 (22%), Positives = 154/444 (34%), Gaps = 49/444 (11%) Query: 531 PSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSL-RCG 589 PS S TQ + + SS P L + +Q APST+HS + P+ P++ + G Sbjct: 582 PSYSVTQMIKTATSPSSSPMLDRHTSQQITT---APSTNHSTIHSTSTSPQESPAVSQRG 638 Query: 590 EASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAE 649 P S ++ V+ P + K + P +S +PS + Sbjct: 639 HTQAPQTTQESQTTRSVS---------PMTDTKTVTTP-GSSFTASGHSPSEIVPQDAPT 688 Query: 650 GSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDE--SLSVSFEQVLP 707 S + +P G+ +PT T S A +G T + + +L+++ V Sbjct: 689 ISAATTFAPAPTGDGHTTQAPT-TALQAAPSSHDATLGPSGGTSLSKTGALTLANSVVST 747 Query: 708 PSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKA--VPMAPAPASPGSSND 765 P P + A S SP D + + E +A PAS GS Sbjct: 748 PGGPEGQ--------WTSASASTSP-DTAAAMTHTHQAESTEASGQTQTSEPASSGSRTT 798 Query: 766 SSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLP 825 S+ + + GA T P S SE + T ++ P D T Sbjct: 799 SAGTATPSSS--GASGTTP-SGSEGISTSGETTRFSSNP---SRDSHTTQSTTELLSASA 852 Query: 826 DPLKVPPPLPDPSSIC--MVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAA 883 +P SSI P + TA + S P A P AA + Sbjct: 853 SHGAIPVSTGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQR 912 Query: 884 AKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSST------PKTATRGPSGSASSRPG 937 +T R S +S S+ ++ P + S T P+T T S S S + Sbjct: 913 TRT------SRGSDTISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTF 966 Query: 938 VSATPPKSPVYLDLAYLPSGSSAH 961 +A + L + Y S S+ H Sbjct: 967 TTAL-ISNATPLPVTYASSASTGH 989 Score = 33.1 bits (74), Expect = 1.4 Identities = 39/144 (27%), Positives = 54/144 (37%), Gaps = 15/144 (10%) Query: 567 STSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALEL 626 ST H PV S S G+ +P S AS ATP A A L Sbjct: 4042 STGHGTPLPVT----STSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTGHATPL 4097 Query: 627 PLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEV 686 P+ + S +P + S S S SPL+ + TP +TTPSL + Sbjct: 4098 PVTSLSSVSTGHATPLAVSSATSASTVSSDSPLK-----------METPGMTTPSLKTDG 4146 Query: 687 GSPHSTEVDESLSVSFEQVLPPSA 710 G +T + S + +P +A Sbjct: 4147 GRRTATSPPPTTSQTIISTIPSTA 4170 >gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sapiens] Length = 2715 Score = 63.5 bits (153), Expect = 1e-09 Identities = 110/460 (23%), Positives = 158/460 (34%), Gaps = 60/460 (13%) Query: 513 RKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSV-PNLKKTNAQAAPKPRKAPSTSHS 571 +K E++ E KK+ + + +E R A + P +K A+ P P P+ S Sbjct: 355 KKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSP- 413 Query: 572 GFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAAS 631 PP P PPS SPP C P V+ P L P P +E+ E P Sbjct: 414 --PP----PLPPPS-----TSPPPPLCPPPPPP-VSPPPLPSPPPPPAQEEQEESPPPVV 461 Query: 632 SIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHS 691 P T S + R P S+R R G G SP TP+ T P + SP Sbjct: 462 ----PATCSRKRGRPPLTPSQRAEREAARAGPEG--TSPPTPTPSTATGGPPED--SPTV 513 Query: 692 TEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPC---EFEHR 748 + + Q + P A S ++ PR P VSP Sbjct: 514 APKSTTFLKNIRQFI---MPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTS 570 Query: 749 KAVPMAPAPA-----SPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLA 803 VP PAP +P + ++R L TS++ LP + P P A Sbjct: 571 PPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPA 630 Query: 804 ----PGAADSDEDTEGFGVPRHDPLPDPLKV------PPPL---------PDPSSICMVD 844 P A S P+ P LK+ PPPL P P+ + Sbjct: 631 PSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAE 690 Query: 845 PEMLPPKTARQTENVS--RTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSAR 902 PE P+ +T ++S R + P +P P A + G + +PL A Sbjct: 691 PE---PRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAP---ALSNGPQTQAQLLQPLQAL 744 Query: 903 SEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATP 942 P + P + + P + GV + P Sbjct: 745 QTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVGSLP 784 Score = 47.8 bits (112), Expect = 6e-05 Identities = 120/538 (22%), Positives = 181/538 (33%), Gaps = 125/538 (23%) Query: 466 GPGRAESKES------VGSRDSSKREGLLATHPRPGQERPGVARKE---PARAEAPRKTE 516 GPG AE E +G R +R L PR + R G R P+R P + Sbjct: 55 GPGGAEPGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGR-GRGRGRGWGPSRGCVPEEES 113 Query: 517 KEAKTPRE------LKKDPKPSVSRTQPREVR--------RAASSVPNLKKTNAQAAPKP 562 + ++ E +D PS R+ R R R + P A AP P Sbjct: 114 SDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPLPPPRLADVAPTP 173 Query: 563 RKAPSTSHS--GFPPV----------ANGPRSPPSLRCGEASPPSAACGSPASQLVATPS 610 K P+ G + A P++P S C E S P + G P P Sbjct: 174 PKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRAC-EPSTPRRSRGRP-------PG 225 Query: 611 LELGPIPAGEEKALELPLAASSIPRPRTPSP-------------ESHRSPAEGSERLSLS 657 GP +++A+ + AA +IP+P P P + P G+ R Sbjct: 226 RPAGPCRR-KQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQ 284 Query: 658 PLRGGEAGPDASPTVTTPTV---TTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSE 714 RGG G P V + + ++G LS+ E E Sbjct: 285 SSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMG---------QLSLGLESG-QGQGQHEE 334 Query: 715 AGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERA 774 + +P R + + SPC + + + ++ + +E Sbjct: 335 SWQDVPQRRVGSGQGG----------SPCWKKQEQKL-----------DDEEEEKKEEEE 373 Query: 775 GGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPL 834 EE +V+E + ++ + L P P P P P PPPL Sbjct: 374 KDKEGEEKEERAVAEEMMPAAEKEEAKLPP-------------PPLTPPAPSP---PPPL 417 Query: 835 PDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKG---LAG 891 P PS+ P PP + P A+ + P P ++ +G L Sbjct: 418 PPPST-SPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTP 476 Query: 892 GDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYL 949 RA R +AR+ P G +P + TP TAT GP + + PKS +L Sbjct: 477 SQRAERE-AARAGPE---GTSP---PTPTPSTATGGPPEDSPT------VAPKSTTFL 521 Score = 46.2 bits (108), Expect = 2e-04 Identities = 111/471 (23%), Positives = 157/471 (33%), Gaps = 99/471 (21%) Query: 496 QERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQ----PREVRRAASSVPNL 551 QE+ +E + E + E E K R + ++ P+ + + P + A S P Sbjct: 357 QEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPP 416 Query: 552 KKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPP---SAACGSPASQLVAT 608 + + P P P PP+ + P PP+ E SPP A C + T Sbjct: 417 LPPPSTSPPPPLCPPPPPPVSPPPLPSPP-PPPAQEEQEESPPPVVPATCSRKRGRPPLT 475 Query: 609 PSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEG------------------ 650 PS E +A +S P P TPS + P + Sbjct: 476 PS------QRAEREAARAGPEGTSPPTP-TPSTATGGPPEDSPTVAPKSTTFLKNIRQFI 528 Query: 651 -------SERLSLSPLRGGEAGP------DASPTVTTPTVTTPSLPAEVGSPHSTEVDES 697 S R+ +P R + P + SP + P T+P +P E S Sbjct: 529 MPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPS------ 582 Query: 698 LSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAP 757 PP APT S P+ P RRS E P AP P Sbjct: 583 ---------PPRAPTPP---STPVPLPEKRRSILREPTFRWTSLTREL---PPPPPAPPP 627 Query: 758 ASPGSSNDSSARSQERAGGLGAEETPPT--------SVSESLPTLSDSDPVPLAPGAADS 809 S + A S R L A + P+ SV P + P P P A DS Sbjct: 628 PPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDS 687 Query: 810 DED--------TEGFGVPRHDP-LPDPLKV---PPPLPDPSSICMVDPEMLPPKTARQTE 857 + T +PR P + P+K P P S+ ++L P A QT+ Sbjct: 688 PAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQ 747 Query: 858 NVSRTRKP----LARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSE 904 + + P L P S P P+ A+ G+ S PLS E Sbjct: 748 LLPQALPPPQPQLQPPPSPQQMP---PLEKARIAGV-----GSLPLSGVEE 790 Score = 43.1 bits (100), Expect = 0.001 Identities = 89/399 (22%), Positives = 129/399 (32%), Gaps = 55/399 (13%) Query: 530 KPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSP-----P 584 +P R +P + A + + + P + P P A SP P Sbjct: 1784 RPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDP 1843 Query: 585 SLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESH 644 LR S P A S + + P+ P G ++ +P P +PS +H Sbjct: 1844 PLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGG-------VSFGPLPSPGSPSSLTH 1896 Query: 645 RSPAEGSERLSLSPLRGGEAGPDA-----SPTVTTPTVTTPSLPAEVGSPHSTEVDESLS 699 P G P R P A S + P T+P L P T V +L+ Sbjct: 1897 HIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRV----PPPTSVVTALT 1952 Query: 700 VSFEQVLPPS---APTSEAGLSLPLRGPRARRSASPHDVD----LCLVSPCEFEHRKAVP 752 + ++ PP +P L S D+D L P + E A Sbjct: 1953 PTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGA 2012 Query: 753 MAPAPASPGSSNDSSARSQER----------AGGLGAEETPPTSVSESLPTLSDSDPVPL 802 M + PG S++ + R A GL TP E L + D Sbjct: 2013 MGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDG----- 2067 Query: 803 APGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRT 862 A++ + G G P P V D + PE LP +E V Sbjct: 2068 TDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRAR----PPEDLP------SEIVDFV 2117 Query: 863 RKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSA 901 K L P A P+ + A LA G + S+ L+A Sbjct: 2118 LKNLGGPGDGGAGPREESLPPAPP--LANGSQPSQGLTA 2154 Score = 35.4 bits (80), Expect = 0.29 Identities = 80/364 (21%), Positives = 116/364 (31%), Gaps = 49/364 (13%) Query: 590 EASPPSAACGSPASQLVATPSLELGPIPAGEE-KALELPLAASSIPRPRTPSPESHRSPA 648 E+SP S P + +V+ P L P + L+ + P +P Sbjct: 2027 ESSPTSRYIHFPVT-VVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPP 2085 Query: 649 EGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPP 708 G + L G AG A P P+ + +G P E+ LPP Sbjct: 2086 SGPGVVRAGVL--GAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPR-----EESLPP 2138 Query: 709 SAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSA 768 + P + S P +G +ASP D + + + PAP P + Sbjct: 2139 APPLANG--SQPSQG----LTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKII 2192 Query: 769 RSQE------RAGGLGAEETPPTSVSESLPTLSDSDPVP--LAPGAADSDEDTEGFGVPR 820 + + G G PP PT+S + P L PG G P Sbjct: 2193 LVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVRP- 2251 Query: 821 HDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVS--RTRKPLARPNSRA----- 873 PPP P P ++ + PP+ A + + VS R P A P +A Sbjct: 2252 ---------APPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDE 2302 Query: 874 --AAPKATPVAAAKTKGLAGGDRASRP-------LSARSEPSEKGGRAPLSRKSSTPKTA 924 A + TP G R P L EP+ + PL +S Sbjct: 2303 DGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLP 2362 Query: 925 TRGP 928 GP Sbjct: 2363 EDGP 2366 >gi|91982772 mucin 17 [Homo sapiens] Length = 4493 Score = 63.5 bits (153), Expect = 1e-09 Identities = 101/466 (21%), Positives = 169/466 (36%), Gaps = 39/466 (8%) Query: 487 LLATHPRPGQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAAS 546 L++T P G E ++ P P T EA + + +S R + Sbjct: 2934 LVSTVPVAGSEASTLSTT-PVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSM 2992 Query: 547 SVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLV 606 SV + +++A+ R TS PV + S E + + S S + Sbjct: 2993 SVSTMPVASSEASTLSRTPADTS----TPVTTSTEASSSPTTAEGTGIPISTPSEGSTPL 3048 Query: 607 ATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGP 666 + + P+ E L S+ P + S +PAEG+ + +S G Sbjct: 3049 TSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTPAEGTS-MPISTYSEG---- 3103 Query: 667 DASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRA 726 ++P P TTP + + + +T VD S V+ S+PT+ G S+P P Sbjct: 3104 -STPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVT-TSTEAHSSPTTSEGTSMPTSTPSE 3161 Query: 727 RRSASPH-DVDLCLVSPCEFEHRKAVPM---APAPASPGSSNDSSARSQERAGGLGAE-E 781 + + V LV E A P+ P S +++ ++A +E Sbjct: 3162 GSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGM 3221 Query: 782 TPPTSVSESLPTLSDSDPVPLAPGAADSD----EDTEGFGVPRHDPLPDPLKVPPPLPDP 837 TP TSV S ++ S+ L+ DS+ TE P P + +P P Sbjct: 3222 TPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASSSP---PTAEGTSMPTSTPSE 3278 Query: 838 SSICMVD-PEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRAS 896 S + P + +T +S T + P + + ++P A D S Sbjct: 3279 GSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQASSSPPIA---------DGTS 3329 Query: 897 RPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATP 942 P S SE G PL+ S + + + S+ P ++TP Sbjct: 3330 MPTSTYSE-----GSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTP 3370 Score = 55.5 bits (132), Expect = 3e-07 Identities = 97/409 (23%), Positives = 155/409 (37%), Gaps = 59/409 (14%) Query: 567 STSHSGFPPVANG---PRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKA 623 ST S P A G P SPPS E + P A+ + +V++ + L P + Sbjct: 1135 STEASSSPTTAEGTSIPTSPPS----EGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQ 1190 Query: 624 LELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLP 683 + ASS P + +P E S L+ P+R + T++T P Sbjct: 1191 VATSTEASSPPPTAEVTSMPTSTPGERSTPLTSMPVRHTPVASSEASTLSTS-------P 1243 Query: 684 AEVGSPHSTEVDESLS-VSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSP 742 + +P +T + S S + E P++ TSE G +L P + + + L +P Sbjct: 1244 VDTSTPVTTSAETSSSPTTAEGTSLPTSTTSE-GSTLLTSIPVSTTLVTSPEASTLLTTP 1302 Query: 743 CEFE----HRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLS--- 795 + + V +P PA G+S +S S+ R S ++ LS Sbjct: 1303 VDTKGPVVTSNEVSSSPTPAE-GTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILSTTP 1361 Query: 796 --DSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTA 853 +S PV + A S +EG +P +P + +SI P P + Sbjct: 1362 VDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPL-------TSI----PVSTTPVVS 1410 Query: 854 RQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAP 913 + +S T + P + +A ++P A + S P S SE G+ P Sbjct: 1411 SEASTLSATPVDTSTPGTTSAEATSSPTTA---------EGISIPTSTPSE-----GKTP 1456 Query: 914 LSRKSSTPKTATRGPSGSASSRPGVSATP--PKSPVYLDLAYLPSGSSA 960 L S P + T + AS+ +S TP SPV A S + A Sbjct: 1457 L---KSIPVSNTPVANSEAST---LSTTPVDSNSPVVTSTAVSSSPTPA 1499 Score = 51.2 bits (121), Expect = 5e-06 Identities = 124/565 (21%), Positives = 193/565 (34%), Gaps = 100/565 (17%) Query: 457 PVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTE 516 PVVT ++ A S E S+ EG P +P + + + P T Sbjct: 2545 PVVTSTEISSS--ATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTS 2602 Query: 517 KEAKTPRELKKDPKP----SVSRTQPREVRRAASS-------VPNLKKTNAQAAPKPRKA 565 T E P S+ + P EV + +S V + + + P + Sbjct: 2603 IPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRT 2662 Query: 566 ---PSTSHSGFPPVANGPRSPPSLRCGEASPP--------SAACGSPASQLVATPSLELG 614 ST S P A G P S GE S P + S AS L TP Sbjct: 2663 LVTTSTGTSSSPTTAEGSSMPTSTP-GERSTPLTNILVSTTLLANSEASTLSTTPVDTST 2721 Query: 615 PIPAGEEKALELPLAASSIPRPRTPSPES--------HRSPAEGSERLSLSPLRGGEAGP 666 P+ E + A + R TPS S P SE ++S + P Sbjct: 2722 PVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIP 2781 Query: 667 -----DASPTVTTPTVT---------------------TPSLPAEVGSPHSTEVDESLSV 700 +AS + TT VT TP +E G+ +T VD S V Sbjct: 2782 VTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPV 2841 Query: 701 SFEQVLPPSAPTSEAGLSLPL-RGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPA--- 756 + S+PT+ G+ +P+ + V V+ E P+ + Sbjct: 2842 T-TSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPV 2900 Query: 757 -PASPGSSNDSSARSQERAGGLGAE-ETPPTSVSESLPTLSDSD-------------PVP 801 ++ GSS+ ++A +E TP TS+ S ++ S+ PV Sbjct: 2901 TTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVT 2960 Query: 802 LAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSR 861 + A+ S EG + P+ P + PL S M P + + +SR Sbjct: 2961 TSAEASSSPTTAEGTSM----PISTPGERRTPLTSMSVSTM-------PVASSEASTLSR 3009 Query: 862 TRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKS-ST 920 T + P + + ++P A T P+S SE S P+S + Sbjct: 3010 TPADTSTPVTTSTEASSSPTTAEGT---------GIPISTPSEGSTPLTSIPVSTTPVAI 3060 Query: 921 PKTATRGPSGSASSRPGVSATPPKS 945 P+ +T + S+ P V++T S Sbjct: 3061 PEASTLSTTPVDSNSPVVTSTEVSS 3085 Score = 50.8 bits (120), Expect = 7e-06 Identities = 91/413 (22%), Positives = 146/413 (35%), Gaps = 40/413 (9%) Query: 554 TNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVA--TP-- 609 T+ + P +P S PV + S + P+ P S TP Sbjct: 1634 TSIPVSTTPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTYTEGRTPLT 1693 Query: 610 SLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSP--AEGSERLSLSPLRGGEAGPD 667 S+ + P L P T S E+ SP +EG+ + +P G Sbjct: 1694 SITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPSEG------ 1747 Query: 668 ASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLP------- 720 +P + P TTP L +E + +T +D S V+ S+PT+ G S+P Sbjct: 1748 TTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVT-TSTEATSSPTTAEGTSIPTSTLSEG 1806 Query: 721 ----LRGPRARRSASPHDVDLCLVSPCEFEH----RKAVPMAPAPASPGSSNDSSARSQE 772 P + + + +P + AV +P PA G+S +S S+ Sbjct: 1807 MTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAE-GTSIATSTPSEG 1865 Query: 773 RAGGLGAEETPPTSVSESLPTLSDSDPV---PLAPGAADSDEDTEGFGVPRHDPLPDPLK 829 + T S TLS + V P+ A S T G P P + Sbjct: 1866 STALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSM--PTSTPRE 1923 Query: 830 VPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGL 889 PPL +SI + + + + ++ TR P+ + +++P + T Sbjct: 1924 GRPPL---TSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSMPTPAY 1980 Query: 890 AGGDR--ASRPLSAR-SEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVS 939 + G S PLS SE + +STP T + S S ++ G S Sbjct: 1981 SEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTS 2033 Score = 48.9 bits (115), Expect = 3e-05 Identities = 86/416 (20%), Positives = 143/416 (34%), Gaps = 30/416 (7%) Query: 540 EVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGF---------PPVANGPRSPPSLRCGE 590 EV +S P+ T + P ++S +G PV ++ S E Sbjct: 2796 EVTSMPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE 2855 Query: 591 ASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPRTPSPESHRSPAEG 650 + S S L+ + + P+ + E L +SIP + S + AEG Sbjct: 2856 GIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTPVDTSIPVTTSTEGSSSPTTAEG 2915 Query: 651 SERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSA 710 + +P ++P + T P +E + +T VD V+ S+ Sbjct: 2916 TSMPISTP------SEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVT-TSAEASSS 2968 Query: 711 PTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPAS-PGSSNDSSAR 769 PT+ G S+P+ P RR +P P + PA S P +++ ++ Sbjct: 2969 PTTAEGTSMPISTPGERR--TPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASS 3026 Query: 770 SQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLK 829 S A G G + P+ S L ++ PV P A V + P+ + Sbjct: 3027 SPTTAEGTGIPISTPSEGSTPLTSI----PVSTTPVAIPEASTLSTTPVDSNSPVVTSTE 3082 Query: 830 V---PPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKATPVAAAKT 886 V P P S E P T T ++ S +TPV + T Sbjct: 3083 VSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAIS-TLSTTPVDTSTPVTTS-T 3140 Query: 887 KGLAGGDRASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATP 942 + + + S PSE G PL+ + + S+ P ++TP Sbjct: 3141 EAHSSPTTSEGTSMPTSTPSE--GSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTP 3194 Score = 48.5 bits (114), Expect = 3e-05 Identities = 106/505 (20%), Positives = 176/505 (34%), Gaps = 89/505 (17%) Query: 502 ARKEPARAEA---PRKTEKEAKTP-RELKKDPKPSVS-RTQPREVRRAASSVPNLKKTNA 556 AR P +E P T E TP + P +S +S P T A Sbjct: 1727 ARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEA 1786 Query: 557 QAAPKPRKAPS----TSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLE 612 ++P + S T G P+ + P S + EAS S S +V + ++ Sbjct: 1787 TSSPTTAEGTSIPTSTLSEGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVS 1846 Query: 613 LGPIPA------------GEEKALELPLAASSIPRPRT----PSPESHRSPAEGSERLSL 656 P PA G +P++ +++ T +P +P ++S Sbjct: 1847 SSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSS 1906 Query: 657 SPLRG-GEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPP------- 708 SP G + P ++P P +T S+P + S+E++ +LS + P Sbjct: 1907 SPTTADGSSMPTSTPREGRPPLT--SIPVSTTTVASSEIN-TLSTTLADTRTPVTTYSQA 1963 Query: 709 -SAPTSEAGLSLPLRGPRARRSASP---HDVDLCLVSPCEFEHRKAVPMAPAPASPGSSN 764 S+PT+ G S+P P ++P + LV E P+ + +P +++ Sbjct: 1964 SSSPTTADGTSMPT--PAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTS--TPATTS 2019 Query: 765 DSSARSQERAGGLGAEETPPTS---------VSESLPTLSDSDPVPLAP----------G 805 + S AGG + + P+ VS +L S+ + + P Sbjct: 2020 TEGSSSPTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNST 2079 Query: 806 AADSDEDTEGFGVPRHDPLP-DPLKVPPPL-------PDPSSICMVDPEMLPPK------ 851 A S EG + P PL PL P+ S++ + P Sbjct: 2080 EASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEV 2139 Query: 852 ---------TARQTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSAR 902 T+ QT S R PL ++ ++ T + + AR Sbjct: 2140 SSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEAR 2199 Query: 903 SEP-SEKGGRAPLSRKS--STPKTA 924 S P + +G P S S STP T+ Sbjct: 2200 SSPTTSEGTSMPTSTPSEGSTPFTS 2224 Score = 47.4 bits (111), Expect = 7e-05 Identities = 107/521 (20%), Positives = 178/521 (34%), Gaps = 91/521 (17%) Query: 509 AEAPRKTEKEAKTP-------RELKKDPKPSVSRTQPREVRR--AASSVPNLKKTNAQAA 559 A P T E TP + L + S T P + S+ + T + Sbjct: 735 ASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTSTEASCSPTTTEGT 794 Query: 560 PKPRKAPSTSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPA- 618 P PS G P + + P S + EAS S S + + + P PA Sbjct: 795 SMPISTPS---EGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPTPAE 851 Query: 619 -----------GEEKALELPLAASSIPR---------------PRTPSPESHRSP--AEG 650 G +P++ + + P T S E+ SP +EG Sbjct: 852 GTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTSEG 911 Query: 651 SERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSA 710 + + +P G ++P + P TTP + +E + +T VD S V+ S+ Sbjct: 912 TSMPTSTP------GEGSTPLTSMPDSTTPVVSSEARTLSATPVDTSTPVT-TSTEATSS 964 Query: 711 PTSEAGLSLPLRGP-RARRSASPHDVDLCLVSPCEFEHRKAVPM-------------APA 756 PT+ G S+P P + V LV+ E P+ +P Sbjct: 965 PTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTSTEASSPP 1024 Query: 757 PASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLS-----DSDPVPLAPGAADSDE 811 P + G+S +S S+ + S TLS S PV A+ S Sbjct: 1025 PTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTTYSQASSSST 1084 Query: 812 DTEGFGVPR------HDPLPD-PLKVPPPLPDPSSICMVDP--EMLPPKTARQTENVSRT 862 +G +P PL P+ + +S P +P T+ + + T Sbjct: 1085 TADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTT 1144 Query: 863 RK----PLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKS 918 + P + P+ + PV+ ++ P+ ++++ A + S Sbjct: 1145 AEGTSIPTSPPSEGTTPLASMPVSTTLVVSSEANTLSTTPVDSKTQV------ATSTEAS 1198 Query: 919 STPKTATRGPSGSASSRPGVSATPPKSPVYLDLAYLPSGSS 959 S P TA + +S PG +TP S + + + P SS Sbjct: 1199 SPPPTAE--VTSMPTSTPGERSTPLTS---MPVRHTPVASS 1234 Score = 47.4 bits (111), Expect = 7e-05 Identities = 118/603 (19%), Positives = 196/603 (32%), Gaps = 60/603 (9%) Query: 457 PVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKTE 516 PV T E + E G S+ EG P P + + P + Sbjct: 3017 PVTT--STEASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSN 3074 Query: 517 KEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPV 576 T E+ P P+ + P S+ T + P + + S PV Sbjct: 3075 SPVVTSTEVSSSPTPAEGTSMPISTYSEGST----PLTGVPVSTTPVTSSAISTLSTTPV 3130 Query: 577 ANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRP 636 +P + S P+ + G+ S +TPS P+ + L SS Sbjct: 3131 DTS--TPVTTSTEAHSSPTTSEGT--SMPTSTPSEGSTPLTYMPVSTM---LVVSSEDST 3183 Query: 637 RTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPT------VTTPTVTTPSLPAEVGSPH 690 + +P +P S + S G + P ++P+ + P TP +E Sbjct: 3184 LSATPVDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILS 3243 Query: 691 STEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGP-RARRSASPHDVDLCLVSPCEFEHRK 749 +T VD + ++ S PT+E G S+P P + V V+ E Sbjct: 3244 TTPVDSNTPLTTSTEASSSPPTAE-GTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLS 3302 Query: 750 AVPM-------------APAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSD 796 P + P + G+S +S S+ + VS TLS Sbjct: 3303 TTPADTSTPVTTYSQASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLST 3362 Query: 797 -----SDPVPLAPGAADSDEDTEGFGVPRHDPLPD--PLKVPPPLPDP---SSICMVDPE 846 S PV + A+ S EG +P P PL P P S + + Sbjct: 3363 TPVDTSTPVTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTT 3422 Query: 847 MLPPKTARQTENVSRTRKPLAR-------PNSRAAAP------KATPVAAAKTKGLAGGD 893 + T T + + +A S + P TPVA+++ L+ Sbjct: 3423 PVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLSTTP 3482 Query: 894 RASRPLSARSEPSEKGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATPPKSPVYLDLAY 953 + S P+ +P + + ++ T+T G + + VS TP S L+ Sbjct: 3483 VDTSTPVTTSSPTNS---SPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLST 3539 Query: 954 LPSGSSAHLVDEEFFQRVRALCYVISGQDQRKEEGMRAVLDALLASKQHWDRDLQVTLIP 1013 P S+ + A V + + EG ++ LL+S + P Sbjct: 3540 TPVDSNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTP 3599 Query: 1014 TFD 1016 + D Sbjct: 3600 SVD 3602 Score = 46.6 bits (109), Expect = 1e-04 Identities = 114/538 (21%), Positives = 179/538 (33%), Gaps = 75/538 (13%) Query: 460 TPQDLEGPGRAESK--------ESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEA 511 TP D PG ++ E + S+ EG P P + + Sbjct: 1419 TPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTT 1478 Query: 512 PRKTEKEAKTPRELKKDPKP----SVSRTQPREVRRAASSVPNLKKTNAQA-------AP 560 P + T + P P S++ + P E A +S+P T A + P Sbjct: 1479 PVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTP 1538 Query: 561 KPRKAPSTSHS---GFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIP 617 P T++S P A+G S E S P + +V++ + L P Sbjct: 1539 AVTSTPVTTYSQASSSPTTADGTSMQTSTY-SEGSTPLTSLPVSTMLVVSSEANTLSTTP 1597 Query: 618 AGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTV 677 + + ASS S + +P+EGS L+ P+ P ASP +T + Sbjct: 1598 IDSKTQVTASTEASSSTTAEGSSM-TISTPSEGSPLLTSIPV---STTPVASPEASTLST 1653 Query: 678 TTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDL 737 T P + SP T + S S+PT G S+P R +P Sbjct: 1654 T----PVDSNSPVITSTEVS-----------SSPTPAEGTSMPTSTYTEGR--TPLTSIT 1696 Query: 738 CLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDS 797 +P + P S + + ARS +P TS S+P + S Sbjct: 1697 VRTTPVASSAISTLSTTPVDNSTPVTTSTEARS-----------SPTTSEGTSMPNSTPS 1745 Query: 798 D---PVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTAR 854 + P+ P + +E + P+ V SS + +P T Sbjct: 1746 EGTTPLTSIPVSTTPVLSSEASTLSA-TPIDTSTPVTTSTEATSSPTTAEGTSIPTSTLS 1804 Query: 855 Q--TENVSRTRKPLARPNSRAAAPKATPV-----AAAKTKGLAGGDRASRPLSARSEPSE 907 + T S NS A+ TPV T + A A S PSE Sbjct: 1805 EGMTPLTSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIATSTPSE 1864 Query: 908 KGGRAPLSRKSSTPKTATRGPSGSASSRPGVSATP-------PKSPVYLDLAYLPSGS 958 G L+ + T + + S+ P V++TP SP D + +P+ + Sbjct: 1865 --GSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTST 1920 Score = 46.6 bits (109), Expect = 1e-04 Identities = 102/503 (20%), Positives = 172/503 (34%), Gaps = 81/503 (16%) Query: 456 EPVVTPQDLEGPGRAESKESVGSRDSSKREGLLATHPRPGQERPGVARKEPARAEAPRKT 515 E +P EG S S G+ + + +H P + P T Sbjct: 2256 EATSSPTTAEGTSIPTSTLSEGTTPLTS---IPVSHTLVANSEVSTLSTTPVDSNTPFTT 2312 Query: 516 EKEAKTP---RELKKDPKPSVSRTQPREVRRAASS--VPNLKKTNAQAAPKPRKAPSTSH 570 EA +P E P + S R S+ V + + + P P T++ Sbjct: 2313 STEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTY 2372 Query: 571 S--GFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPL 628 S G P S P+ E S P S+ + +P +A Sbjct: 2373 SQAGSSPTTADDTSMPTSTYSEGSTPLT-------------SVPVSTMPVVSSEASTHST 2419 Query: 629 AASSIPRPRTPSPESHRSP--AEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEV 686 P T S E+ SP AEG+ + P G +P + P TTP + +E Sbjct: 2420 TPVDTSTPVTTSTEASSSPTTAEGTSIPTSPPSEG------TTPLASMPVSTTPVVSSEA 2473 Query: 687 GSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFE 746 G+ +T VD S ++ S+PT+ + +P+ +AS L Sbjct: 2474 GTLSTTPVDTSTPMT-TSTEASSSPTTAEDIVVPI------STASEGSTLL--------- 2517 Query: 747 HRKAVPMAPAP-ASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPG 805 ++P++ P ASP +S S+ T V + P ++ ++ A Sbjct: 2518 --TSIPVSTTPVASPEASTLST-----------------TPVDSNSPVVTSTEISSSATS 2558 Query: 806 AADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDP--EMLPPKTARQTENVSRTR 863 A + T + P+ P +S P +P T+ +T + T Sbjct: 2559 AEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTA 2618 Query: 864 K----PLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSS 919 K P++ P+ + + + V+ ++ P+ R+ + G SS Sbjct: 2619 KDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTG------TSS 2672 Query: 920 TPKTATRGPSGSASSRPGVSATP 942 +P TA S +S PG +TP Sbjct: 2673 SPTTAE--GSSMPTSTPGERSTP 2693 Score = 45.1 bits (105), Expect = 4e-04 Identities = 100/450 (22%), Positives = 158/450 (35%), Gaps = 69/450 (15%) Query: 531 PSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGE 590 P S+TQ A+SS A+ + APS G P + + P S + E Sbjct: 2068 PVDSKTQVTNSTEASSSA------TAEGSSMTISAPS---EGSPLLTSIPLSTTPVASPE 2118 Query: 591 ASPPSAACGSPASQLVATPSLELGPIPAG----------------EEKALELPLAASSIP 634 AS S S ++ + + PIP + + ASS Sbjct: 2119 ASTLSTTPVDSNSPVITSTEVSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAI 2178 Query: 635 RPRTPSPESHRSPAEGSERLSLSPLRG-GEAGPDASPT------VTTPTVTTPSLPAEVG 687 + +P +P S SP G + P ++P+ + P T P + +E Sbjct: 2179 STLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEAS 2238 Query: 688 SPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRG-PRARRSASPHDVDLCLVSPCEFE 746 + +T VD S V+ S+PT+ G S+P + V LV+ E Sbjct: 2239 TLSATPVDTSTPVT-TSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVANSE-- 2295 Query: 747 HRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSD------PV 800 ++ +P SN S E A PPT+ S+PT + S+ + Sbjct: 2296 ------VSTLSTTPVDSNTPFTTSTE------ASSPPPTAEGTSMPTSTSSEGNTPLTRM 2343 Query: 801 PLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQ--TEN 858 P++ S E + P P V SS D +P T + T Sbjct: 2344 PVSTTMVASFETSTLSTTPADTSTP----VTTYSQAGSSPTTADDTSMPTSTYSEGSTPL 2399 Query: 859 VSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSAR------SEPSEKGGRA 912 S + +S A+ TPV + T + +S P +A S PSE G Sbjct: 2400 TSVPVSTMPVVSSEASTHSTTPVDTS-TPVTTSTEASSSPTTAEGTSIPTSPPSE--GTT 2456 Query: 913 PLSRKSSTPKTATRGPSGSASSRPGVSATP 942 PL+ + +G+ S+ P ++TP Sbjct: 2457 PLASMPVSTTPVVSSEAGTLSTTPVDTSTP 2486 Score = 44.7 bits (104), Expect = 5e-04 Identities = 100/439 (22%), Positives = 154/439 (35%), Gaps = 55/439 (12%) Query: 567 STSHSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALEL 626 ST + A G P S E S P + + + ++ + L P + Sbjct: 663 STEATSSSTTAEGTSMPTSTYT-EGSTPLTSMPVNTTLVASSEASTLSTTPVDTSTPVTT 721 Query: 627 PLAASSIPRPRTPSPESHRSPAEGSERLSLSP-----LRGGEAGPDASPTVTTPTVTTPS 681 ASS P + +P+EGS L+ P L EA ++ + T T T S Sbjct: 722 STEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITTS 781 Query: 682 LPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARR-SASPHDVDLCLV 740 A SP +TE S+ +S P + ++ P+ P A S +P D + + Sbjct: 782 TEASC-SPTTTE-GTSMPISTPSEGSPLLTSIPVSIT-PVTSPEASTLSTTPVDSNSPVT 838 Query: 741 SPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLS----- 795 + E V +P PA G+S +S S+ R + + ++ TLS Sbjct: 839 TSTE------VSSSPTPAE-GTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVD 891 Query: 796 DSDPVPLAPGAADSDEDTEGFGVPRHDP---------LPDPLKVPPPLPDPSSICMVDPE 846 S PV + A S +EG +P P +PD P + + P Sbjct: 892 TSTPVTNSTEARSSPTTSEGTSMPTSTPGEGSTPLTSMPD--STTPVVSSEARTLSATPV 949 Query: 847 MLPPKTARQTENVSR------TRKPLARPNSRAAAPKATPV-------AAAKTKGLAGGD 893 TE S T P + P+ +TPV + A T D Sbjct: 950 DTSTPVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVD 1009 Query: 894 RASRPLSARSE-----PSEKGGRAPLSRKSSTPKTATRGPSGS---ASSRPGVSATPPKS 945 ++ PL+ +E P+ +G P S S TR P + ASS +T P Sbjct: 1010 -SNTPLTTSTEASSPPPTAEGTSMPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPAD 1068 Query: 946 PVYLDLAYLPSGSSAHLVD 964 Y + SS+ D Sbjct: 1069 TSTPVTTYSQASSSSTTAD 1087 Score = 41.6 bits (96), Expect = 0.004 Identities = 108/505 (21%), Positives = 158/505 (31%), Gaps = 108/505 (21%) Query: 460 TPQDLEGPGRAESKESVGSRDS-----------SKREGLLATHPRPGQERPGVARKE--- 505 +P EGP + S S GS S L+T P P + E Sbjct: 256 SPTTAEGPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPA-ATNIPVITSTEASS 314 Query: 506 -PARAEA---PRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPK 561 P AE P T E TP V+ ++ + L T+ + + Sbjct: 315 SPTTAEGTSIPTSTYTEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTTSTEPSSL 374 Query: 562 PRKAPSTS------HSGFPPVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGP 615 P A +TS G P+ N P S + EAS S Sbjct: 375 PTTAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTST------------------- 415 Query: 616 IPAGEEKALELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTP 675 IP + + ASS P + + +P+EGS +P + P Sbjct: 416 IPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGS-----------------TPLTSMP 458 Query: 676 TVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDV 735 TTP +E + +T VD V+ S PT+E S+P P Sbjct: 459 VSTTPVASSEASNLSTTPVDSKTQVTTSTEASSSPPTAEVN-SMPTSTPSEGS------- 510 Query: 736 DLCLVSPCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLS 795 +P +P+A + AS S+ T V S P + Sbjct: 511 -----TPLTSMSVSTMPVASSEASTLST---------------------TPVDTSTPVTT 544 Query: 796 DSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQ 855 S+ A+ S EG +P P P S+ +V E T Sbjct: 545 SSE-------ASSSSTTPEGTSIPTSTPSEG--STPLTNMPVSTRLVVSSEASTTSTTPA 595 Query: 856 TENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLA-GGDRASRPLSARSEPSEKGGRAPL 914 N T A +S A + P + +G S L A SE S P+ Sbjct: 596 DSNTFVTTSSEASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTL-STTPV 654 Query: 915 SRKSSTPKTATRGPSGSASSRPGVS 939 S+TP T + + S+++ G S Sbjct: 655 D--SNTPVTTSTEATSSSTTAEGTS 677 Score = 40.4 bits (93), Expect = 0.009 Identities = 88/385 (22%), Positives = 143/385 (37%), Gaps = 42/385 (10%) Query: 567 STSHSGFPPVANG---PRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKA 623 ST S P A G P S PS E + P A+ + +V++ L P Sbjct: 3374 STEASLSPTTAEGTSIPTSSPS----EGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTL 3429 Query: 624 LELPLAASSIPRPRTPSPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLP 683 + ASS P + + +EGS LS+ PL +P ++ T + P Sbjct: 3430 VTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPL-------STTPVASSEASTLSTTP 3482 Query: 684 AEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGL-SLPLRG-PRARRSASPHDVDLCLVS 741 + +P +T + S + +V S PTS AG S PL P + + + + Sbjct: 3483 VDTSTPVTTSSPTNSSPTTAEV--TSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTT 3540 Query: 742 PCEFEHRKAVPMAPAPASPGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVP 801 P + + + A +SP + ++ R + G + T +S + T S++ Sbjct: 3541 PVD-SNTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTT--MLLSSTYVTSSEAS--- 3594 Query: 802 LAPGAADSDEDTEGFGVPRHDPLPDPLKV-PPPLPDPSSICMVDPEMLPPKTARQTENVS 860 P D T + + P P +V P+ PS + ++P T T + + Sbjct: 3595 -TPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEV-STPLTIMPVSTTSVTISEA 3652 Query: 861 RTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAPLSRKSST 920 T L S P T + + G + P+ SE G PL ++ Sbjct: 3653 GTASTLPVDTS---TPVITSTQVSSSPVTPEG--TTMPIWTPSE-----GSTPL---TTM 3699 Query: 921 PKTATRGPS--GSASSRPGVSATPP 943 P + TR S GS S P V + P Sbjct: 3700 PVSTTRVTSSEGSTLSTPSVVTSTP 3724 Score = 35.8 bits (81), Expect = 0.22 Identities = 110/502 (21%), Positives = 164/502 (32%), Gaps = 94/502 (18%) Query: 515 TEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKTNAQAAPKPRKAPSTSHSGFP 574 T EA TP PSV R+ P ++S P T + P PS + Sbjct: 3589 TSSEASTPST------PSVDRSTPVTTSTQSNSTP----TPPEVITLPMSTPSEVST--- 3635 Query: 575 PVANGPRSPPSLRCGEASPPSAACGSPASQLVATPSLELGPI-PAGEEKALELPLAASSI 633 P+ P S S+ EA S ++ ++ + + P+ P G + P + S Sbjct: 3636 PLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTP-SEGST 3694 Query: 634 PRPRTPSPESHRSPAEGS-----------------ERLSLS------------PLRGGEA 664 P P + + +EGS E +S S P+ Sbjct: 3695 PLTTMPVSTTRVTSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTL 3754 Query: 665 GP----DASPTVTTPTVTTPSLPAEVGSPHSTEVDESLSVSFEQVLPPSAPTSEAGLSLP 720 G +P P +TPS+P+ S T E S S T E ++P Sbjct: 3755 GTTILVSTTPVTRFPESSTPSIPSVYTSMSMTTASEGSS---------SPTTLEGTTTMP 3805 Query: 721 LRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPAS----PGSSNDSSARSQERAG- 775 + R + + L+SP M+P+ AS P + + +AG Sbjct: 3806 MSTTSERSTL----LTTVLISPISV-------MSPSEASTLSTPPGDTSTPLLTSTKAGS 3854 Query: 776 -GLGAEETP-----PTSVSESLPTLSDSDPVPLA-PGAADSDE---DTEGFGVPRHDPLP 825 + AE T + S L TL S +P + PGA+ + DT P D Sbjct: 3855 FSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTAS 3914 Query: 826 DPLKVPPPLPDPSSICMVDPEMLPPKT--ARQTENVSRTRKPLARPNSRAAAPKATPVAA 883 P P+ S+ ++ P T T S T + P T Sbjct: 3915 TP---TIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTEL 3971 Query: 884 AKTKGLAGGDRASRPLSARSEPSEKGGRAPL-----SRKSSTPKTATRGPSGSASSRPGV 938 + S + APL S STP+T +RG + SAS+ Sbjct: 3972 NTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGCTTSASTLSAT 4031 Query: 939 SATPPKSPVYLDLAYLPSGSSA 960 S TP S PS S+ Sbjct: 4032 S-TPHTSTSVTTRPVTPSSESS 4052 Score = 33.1 bits (74), Expect = 1.4 Identities = 74/376 (19%), Positives = 135/376 (35%), Gaps = 46/376 (12%) Query: 584 PSLRCGEASPPSAACGSPASQLVATPSLELGPIPAGEEKALELPLAASS----IPRPRTP 639 P R E+S PS S + + T + E P E +P++ +S + Sbjct: 3764 PVTRFPESSTPSIP--SVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLI 3821 Query: 640 SPESHRSPAEGSERLSLSPLRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHSTEVDESLS 699 SP S SP+E S LS P G ++P +T+ + S+PAEV + + E + Sbjct: 3822 SPISVMSPSEAST-LSTPP------GDTSTPLLTSTKAGSFSIPAEVTTIRISITSERST 3874 Query: 700 VSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEHRKAVPMAPAPAS 759 ++ + PTS G S+ P + D +V + ++ Sbjct: 3875 PLTTLLVSTTLPTSFPGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGST 3934 Query: 760 PGSSNDSSARSQERAGGLGAEETPPTSVSESLPTLSDSDPVPLAPGAADSDEDTEGFGVP 819 PG++ + + A+ P T+ + S P ++ ++ L + S T F Sbjct: 3935 PGTTIFIPSTPVTSS---TADVFPATTGAVSTPVITSTE---LNTPSTSSSSTTTSFSTT 3988 Query: 820 RHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTARQTENVSRTRKPLARPNSRAAAPKAT 879 + P + PL + + M P T+R + T + P++ Sbjct: 3989 KEFTTP-AMTTAAPL---TYVTMSTAPSTPRTTSRGCTTSASTLSATSTPHTS------- 4037 Query: 880 PVAAAKTKGLAGGDRASRPLSARSE--------------PSEKGGRAPLSRKSSTPKTAT 925 + T+ + +SRP + S P+ ++ ++ T T Sbjct: 4038 --TSVTTRPVTPSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEAVTTMTTR 4095 Query: 926 RGPSGSASSRPGVSAT 941 PS +S P V+ T Sbjct: 4096 TKPSTRTTSFPTVTTT 4111 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.393 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 51,632,383 Number of Sequences: 37866 Number of extensions: 3127459 Number of successful extensions: 20582 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 115 Number of HSP's successfully gapped in prelim test: 1577 Number of HSP's that attempted gapping in prelim test: 13605 Number of HSP's gapped (non-prelim): 6372 length of query: 1059 length of database: 18,247,518 effective HSP length: 113 effective length of query: 946 effective length of database: 13,968,660 effective search space: 13214352360 effective search space used: 13214352360 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.