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Search of human proteins with 5031913
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031913 melan-A [Homo sapiens]
(118 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5031913 melan-A [Homo sapiens] 254 1e-68
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 32 0.11
gi|30179915 paired immunoglobulin-like type 2 receptor beta isof... 31 0.18
gi|30179911 paired immunoglobulin-like type 2 receptor beta isof... 31 0.18
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 30 0.53
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 30 0.53
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 30 0.53
gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo ... 29 0.91
gi|94721263 myotubularin related protein 12 [Homo sapiens] 29 0.91
gi|149999378 inverted formin 2 isoform 2 [Homo sapiens] 28 2.0
gi|149999380 inverted formin 2 isoform 1 [Homo sapiens] 28 2.0
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 27 2.6
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 27 2.6
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 27 2.6
gi|41281683 disabled homolog 2 interacting protein isoform 2 [Ho... 27 2.6
gi|94967023 disabled homolog 2 interacting protein isoform 1 [Ho... 27 2.6
gi|4758316 ets variant gene 5 (ets-related molecule) [Homo sapiens] 27 2.6
gi|62953127 polyhomeotic 1-like [Homo sapiens] 27 2.6
gi|38492356 DNA-directed DNA polymerase delta 3 [Homo sapiens] 27 3.5
gi|20070323 solute carrier family 30 (zinc transporter), member ... 27 3.5
gi|148539558 dystrophin related protein 2 [Homo sapiens] 27 3.5
gi|194097442 protein tyrosine phosphatase, receptor type, N poly... 27 4.5
gi|194097440 protein tyrosine phosphatase, receptor type, N poly... 27 4.5
gi|194097438 protein tyrosine phosphatase, receptor type, N poly... 27 4.5
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 27 4.5
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 27 4.5
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 27 4.5
gi|34101290 Fas apoptotic inhibitory molecule 2 [Homo sapiens] 27 4.5
gi|30179909 paired immunoglobulin-like type 2 receptor alpha iso... 26 5.9
gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens] 26 5.9
>gi|5031913 melan-A [Homo sapiens]
Length = 118
Score = 254 bits (649), Expect = 1e-68
Identities = 118/118 (100%), Positives = 118/118 (100%)
Query: 1 MPREDAHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVLLLIGCWYCRRRNGYRALMDK 60
MPREDAHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVLLLIGCWYCRRRNGYRALMDK
Sbjct: 1 MPREDAHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVLLLIGCWYCRRRNGYRALMDK 60
Query: 61 SLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP 118
SLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP
Sbjct: 61 SLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP 118
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 32.0 bits (71), Expect = 0.11
Identities = 21/76 (27%), Positives = 30/76 (39%), Gaps = 10/76 (13%)
Query: 41 LLIGCWYCRRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNA 100
LLI C +C R +H G + T ++ D VS Q +PV P A
Sbjct: 1519 LLIQCRHCERW----------MHAGCESLFTEDDVEQAADEGFDCVSCQPYVVKPVAPVA 1568
Query: 101 PPAYEKLSAEQSPPPY 116
PP + ++ P Y
Sbjct: 1569 PPELVPMKVKEPEPQY 1584
>gi|30179915 paired immunoglobulin-like type 2 receptor beta isoform
a precursor [Homo sapiens]
Length = 227
Score = 31.2 bits (69), Expect = 0.18
Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 7/48 (14%)
Query: 15 KGHGHSY-----TTAEEAAGIGIL-TVILGVLLLIGCWYCRRRNGYRA 56
KGH S+ T A + +L TVILG+L L+ W+ RRR G RA
Sbjct: 176 KGHSESWHLSLDTAIRVALAVAVLKTVILGLLCLLLLWW-RRRKGSRA 222
>gi|30179911 paired immunoglobulin-like type 2 receptor beta isoform
a precursor [Homo sapiens]
Length = 227
Score = 31.2 bits (69), Expect = 0.18
Identities = 21/48 (43%), Positives = 27/48 (56%), Gaps = 7/48 (14%)
Query: 15 KGHGHSY-----TTAEEAAGIGIL-TVILGVLLLIGCWYCRRRNGYRA 56
KGH S+ T A + +L TVILG+L L+ W+ RRR G RA
Sbjct: 176 KGHSESWHLSLDTAIRVALAVAVLKTVILGLLCLLLLWW-RRRKGSRA 222
>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
Length = 1072
Score = 29.6 bits (65), Expect = 0.53
Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 2/28 (7%)
Query: 31 GILTVILGVLLLIGCWYCR--RRNGYRA 56
GI+TVIL +L+++ YCR +NGY A
Sbjct: 887 GIMTVILIILIVVMARYCRSKNKNGYEA 914
>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
Length = 1200
Score = 29.6 bits (65), Expect = 0.53
Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 2/28 (7%)
Query: 31 GILTVILGVLLLIGCWYCR--RRNGYRA 56
GI+TVIL +L+++ YCR +NGY A
Sbjct: 840 GIMTVILIILIVVMARYCRSKNKNGYEA 867
>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
Length = 1069
Score = 29.6 bits (65), Expect = 0.53
Identities = 14/28 (50%), Positives = 20/28 (71%), Gaps = 2/28 (7%)
Query: 31 GILTVILGVLLLIGCWYCR--RRNGYRA 56
GI+TVIL +L+++ YCR +NGY A
Sbjct: 887 GIMTVILIILIVVMARYCRSKNKNGYEA 914
>gi|15451844 ADAM metallopeptidase domain 19 preproprotein [Homo
sapiens]
Length = 918
Score = 28.9 bits (63), Expect = 0.91
Identities = 31/114 (27%), Positives = 45/114 (39%), Gaps = 15/114 (13%)
Query: 16 GHGHSYTTAE---EAAG---IGILTVILGVLLLIGCWYCRRRNGYRALMDKSLHVGTQCA 69
GHG S + E+ G G+L IL + +L+ +YC R+N + S + ++
Sbjct: 685 GHGGSIDSGPMPPESVGPVVAGVLVAILVLAVLMLMYYCCRQNNKLGQLKPSA-LPSKLR 743
Query: 70 LTRRCP-----QEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP 118
CP G H + LQ + V N P E L PPP P
Sbjct: 744 QQFSCPFRVSQNSGTGHANPTFKLQTPQGKRKVINTP---EILRKPSQPPPRPP 794
>gi|94721263 myotubularin related protein 12 [Homo sapiens]
Length = 747
Score = 28.9 bits (63), Expect = 0.91
Identities = 19/60 (31%), Positives = 29/60 (48%), Gaps = 1/60 (1%)
Query: 47 YCRRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCE-PVVPNAPPAYE 105
+CR R G+++L+ K +G C L R D + V L +C +V PPA+E
Sbjct: 412 HCRTRIGFQSLIQKEWVMGGHCFLDRCNHLRQNDKEEVPVFLLFLDCVWQLVHQHPPAFE 471
>gi|149999378 inverted formin 2 isoform 2 [Homo sapiens]
Length = 1240
Score = 27.7 bits (60), Expect = 2.0
Identities = 23/62 (37%), Positives = 26/62 (41%), Gaps = 10/62 (16%)
Query: 65 GTQCALTRRCPQEGFDHRDS----KVS----LQEKNCEPVVPNAPPAYEKLSAEQSPPPY 116
G Q A C E DH S KVS L+++ P P PP SAE PPP
Sbjct: 385 GQQPAAAAAC--EPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPP 442
Query: 117 SP 118
P
Sbjct: 443 PP 444
>gi|149999380 inverted formin 2 isoform 1 [Homo sapiens]
Length = 1249
Score = 27.7 bits (60), Expect = 2.0
Identities = 23/62 (37%), Positives = 26/62 (41%), Gaps = 10/62 (16%)
Query: 65 GTQCALTRRCPQEGFDHRDS----KVS----LQEKNCEPVVPNAPPAYEKLSAEQSPPPY 116
G Q A C E DH S KVS L+++ P P PP SAE PPP
Sbjct: 385 GQQPAAAAAC--EPVDHAQSESILKVSQPRALEQQASTPPPPPPPPLLPGSSAEPPPPPP 442
Query: 117 SP 118
P
Sbjct: 443 PP 444
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 27.3 bits (59), Expect = 2.6
Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 6/66 (9%)
Query: 49 RRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLS 108
R G R+L+ K L+VG R P G H + SL NC P P S
Sbjct: 1053 RFSGGGRSLIKKRLYVGEP----HRGP--GLPHGGTGRSLSSPNCFGPQPGGPEMRRVNS 1106
Query: 109 AEQSPP 114
A ++PP
Sbjct: 1107 AGRAPP 1112
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 27.3 bits (59), Expect = 2.6
Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 6/66 (9%)
Query: 49 RRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLS 108
R G R+L+ K L+VG R P G H + SL NC P P S
Sbjct: 1053 RFSGGGRSLIKKRLYVGEP----HRGP--GLPHGGTGRSLSSPNCFGPQPGGPEMRRVNS 1106
Query: 109 AEQSPP 114
A ++PP
Sbjct: 1107 AGRAPP 1112
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sapiens]
Length = 1188
Score = 27.3 bits (59), Expect = 2.6
Identities = 22/66 (33%), Positives = 28/66 (42%), Gaps = 6/66 (9%)
Query: 49 RRRNGYRALMDKSLHVGTQCALTRRCPQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLS 108
R G R+L+ K L+VG R P G H + SL NC P P S
Sbjct: 1053 RFSGGGRSLIKKRLYVGEP----HRGP--GLPHGGTGRSLSSPNCFGPQPGGPEMRRVNS 1106
Query: 109 AEQSPP 114
A ++PP
Sbjct: 1107 AGRAPP 1112
>gi|41281683 disabled homolog 2 interacting protein isoform 2 [Homo
sapiens]
Length = 1065
Score = 27.3 bits (59), Expect = 2.6
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 85 KVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP 118
++SL EK +P VP A + +Q PPP P
Sbjct: 769 QMSLTEKGGQPTVPRQNSAGPQRRIDQPPPPPPP 802
>gi|94967023 disabled homolog 2 interacting protein isoform 1 [Homo
sapiens]
Length = 1132
Score = 27.3 bits (59), Expect = 2.6
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 85 KVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP 118
++SL EK +P VP A + +Q PPP P
Sbjct: 865 QMSLTEKGGQPTVPRQNSAGPQRRIDQPPPPPPP 898
>gi|4758316 ets variant gene 5 (ets-related molecule) [Homo sapiens]
Length = 510
Score = 27.3 bits (59), Expect = 2.6
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 1/42 (2%)
Query: 75 PQEGFDHRDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPY 116
PQ G D++ S + EP+VP APP + E P Y
Sbjct: 231 PQPGVPG-DNRPSYHRQMSEPIVPAAPPPPQGFKQEYHDPLY 271
>gi|62953127 polyhomeotic 1-like [Homo sapiens]
Length = 1004
Score = 27.3 bits (59), Expect = 2.6
Identities = 13/26 (50%), Positives = 15/26 (57%), Gaps = 2/26 (7%)
Query: 95 PVVPNAPPAY--EKLSAEQSPPPYSP 118
PV P PP K+SA Q PPP+ P
Sbjct: 501 PVAPIKPPQLGAAKMSAAQQPPPHIP 526
>gi|38492356 DNA-directed DNA polymerase delta 3 [Homo sapiens]
Length = 466
Score = 26.9 bits (58), Expect = 3.5
Identities = 13/37 (35%), Positives = 19/37 (51%)
Query: 82 RDSKVSLQEKNCEPVVPNAPPAYEKLSAEQSPPPYSP 118
R K+ + + + V P++P AYE S PPP P
Sbjct: 322 RRIKLPESDSSEDEVFPDSPGAYEAESPSPPPPPSPP 358
>gi|20070323 solute carrier family 30 (zinc transporter), member 5
isoform 1 [Homo sapiens]
Length = 765
Score = 26.9 bits (58), Expect = 3.5
Identities = 12/35 (34%), Positives = 19/35 (54%)
Query: 6 AHFIYGYPKKGHGHSYTTAEEAAGIGILTVILGVL 40
+H ++G+ GHGHS+ +A + V L VL
Sbjct: 563 SHHMHGHSDHGHGHSHGSAGGGMNANMRGVFLHVL 597
>gi|148539558 dystrophin related protein 2 [Homo sapiens]
Length = 957
Score = 26.9 bits (58), Expect = 3.5
Identities = 10/32 (31%), Positives = 20/32 (62%)
Query: 54 YRALMDKSLHVGTQCALTRRCPQEGFDHRDSK 85
+R + + + T+C++ R+CP +GF +R K
Sbjct: 596 HRVTIAEQVKHQTKCSICRQCPIKGFRYRSLK 627
>gi|194097442 protein tyrosine phosphatase, receptor type, N
polypeptide 2 isoform 3 precursor [Homo sapiens]
Length = 986
Score = 26.6 bits (57), Expect = 4.5
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 33 LTVILGVLLLIGCWYCRRRNGYRALMDKSLHVG 65
L ILGVLL G YC R + L +K +G
Sbjct: 594 LACILGVLLASGLIYCLRHSSQHRLKEKLSGLG 626
>gi|194097440 protein tyrosine phosphatase, receptor type, N
polypeptide 2 isoform 1 precursor [Homo sapiens]
Length = 1015
Score = 26.6 bits (57), Expect = 4.5
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 33 LTVILGVLLLIGCWYCRRRNGYRALMDKSLHVG 65
L ILGVLL G YC R + L +K +G
Sbjct: 623 LACILGVLLASGLIYCLRHSSQHRLKEKLSGLG 655
>gi|194097438 protein tyrosine phosphatase, receptor type, N
polypeptide 2 isoform 2 precursor [Homo sapiens]
Length = 998
Score = 26.6 bits (57), Expect = 4.5
Identities = 14/33 (42%), Positives = 17/33 (51%)
Query: 33 LTVILGVLLLIGCWYCRRRNGYRALMDKSLHVG 65
L ILGVLL G YC R + L +K +G
Sbjct: 606 LACILGVLLASGLIYCLRHSSQHRLKEKLSGLG 638
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 26.6 bits (57), Expect = 4.5
Identities = 10/22 (45%), Positives = 14/22 (63%)
Query: 97 VPNAPPAYEKLSAEQSPPPYSP 118
VP +PPA +S +PPP +P
Sbjct: 481 VPPSPPASPPMSPSATPPPQAP 502
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 26.6 bits (57), Expect = 4.5
Identities = 10/22 (45%), Positives = 14/22 (63%)
Query: 97 VPNAPPAYEKLSAEQSPPPYSP 118
VP +PPA +S +PPP +P
Sbjct: 706 VPPSPPASPPMSPSATPPPQAP 727
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 26.6 bits (57), Expect = 4.5
Identities = 10/22 (45%), Positives = 14/22 (63%)
Query: 97 VPNAPPAYEKLSAEQSPPPYSP 118
VP +PPA +S +PPP +P
Sbjct: 442 VPPSPPASPPMSPSATPPPQAP 463
>gi|34101290 Fas apoptotic inhibitory molecule 2 [Homo sapiens]
Length = 316
Score = 26.6 bits (57), Expect = 4.5
Identities = 10/20 (50%), Positives = 15/20 (75%)
Query: 90 EKNCEPVVPNAPPAYEKLSA 109
EK P VP+APP+YE+ ++
Sbjct: 24 EKKEAPAVPSAPPSYEEATS 43
>gi|30179909 paired immunoglobulin-like type 2 receptor alpha
isoform 1 precursor [Homo sapiens]
Length = 303
Score = 26.2 bits (56), Expect = 5.9
Identities = 24/118 (20%), Positives = 45/118 (38%), Gaps = 30/118 (25%)
Query: 21 YTTAEEAAGIGILTVILGVLLL--IGCWYCRRRNGYRALMDKSLHVGTQCALTRRCPQEG 78
+ + E A G+ + +LG+++L I RRR G + T+ R P +
Sbjct: 191 HISLETAVGVAVAVTVLGIMILGLICLLRWRRRKGQQR---------TKATTPAREPFQN 241
Query: 79 FDHRDSKVSLQEKNCEPVV-------------------PNAPPAYEKLSAEQSPPPYS 117
+ + + +N +P + P APP++ L + Q+ YS
Sbjct: 242 TEEPYENIRNEGQNTDPKLNPKDDGIVYASLALSSSTSPRAPPSHRPLKSPQNETLYS 299
>gi|66346693 FAT tumor suppressor 1 precursor [Homo sapiens]
Length = 4588
Score = 26.2 bits (56), Expect = 5.9
Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 11/83 (13%)
Query: 27 AAGIGILTVILGVLLLIGCW-YCRR---RNGYRALMDKSLHVGTQCALTRRCPQEGFDHR 82
A GIGI+ + G+ LL+ + CR+ R K H+G A +R +
Sbjct: 4180 AEGIGIVVFVAGIFLLVVVFVLCRKMISRKKKHQAEPKDKHLGPATAFLQR------PYF 4233
Query: 83 DSKVSLQ-EKNCEPVVPNAPPAY 104
DSK++ + P VP P +Y
Sbjct: 4234 DSKLNKNIYSDIPPQVPVRPISY 4256
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.443
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,492,837
Number of Sequences: 37866
Number of extensions: 229367
Number of successful extensions: 934
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 892
Number of HSP's gapped (non-prelim): 52
length of query: 118
length of database: 18,247,518
effective HSP length: 88
effective length of query: 30
effective length of database: 14,915,310
effective search space: 447459300
effective search space used: 447459300
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.