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Search of human proteins with 5031701
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5031701 follistatin-like 3 glycoprotein precursor [Homo
sapiens]
(263 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] 579 e-165
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 232 2e-61
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 232 2e-61
gi|54873613 agrin [Homo sapiens] 80 1e-15
gi|29568105 transmembrane protein with EGF-like and two follista... 69 5e-12
gi|190194423 SPARC-like 1 [Homo sapiens] 59 3e-09
gi|190341024 SPARC-like 1 [Homo sapiens] 59 3e-09
gi|5901956 follistatin-like 1 precursor [Homo sapiens] 55 6e-08
gi|12383051 transmembrane protein with EGF-like and two follista... 54 2e-07
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 49 4e-06
gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens] 48 8e-06
gi|4504619 insulin-like growth factor binding protein 7 [Homo sa... 46 3e-05
gi|54792136 follistatin-like 4 [Homo sapiens] 45 5e-05
gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 45 5e-05
gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 45 5e-05
gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and n... 44 1e-04
gi|190358524 follistatin-like 5 isoform c [Homo sapiens] 43 2e-04
gi|190358522 follistatin-like 5 isoform b [Homo sapiens] 43 2e-04
gi|190358520 follistatin-like 5 isoform a [Homo sapiens] 43 2e-04
gi|93102379 low density lipoprotein-related protein 1B precursor... 42 4e-04
gi|56237021 fibrillin 3 precursor [Homo sapiens] 42 5e-04
gi|7657453 serine peptidase inhibitor, Kazal type 4 [Homo sapiens] 42 5e-04
gi|28212222 WFIKKN2 protein [Homo sapiens] 42 7e-04
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 41 0.001
gi|56090548 insulin-like growth factor binding protein-like 1 [H... 41 0.001
gi|225690544 keratin associated protein 4-11 [Homo sapiens] 41 0.001
gi|169212028 PREDICTED: keratin-associated protein 9-2-like 2-li... 41 0.001
gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain conta... 41 0.001
gi|21264602 laminin alpha 5 [Homo sapiens] 40 0.003
gi|123702038 keratin associated protein 5-9 [Homo sapiens] 40 0.003
>gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]
Length = 263
Score = 579 bits (1492), Expect = e-165
Identities = 263/263 (100%), Positives = 263/263 (100%)
Query: 1 MRPGAPGPLWPLPWGALAWAVGFVSSMGSGNPAPGGVCWLQQGQEATCSLVLQTDVTRAE 60
MRPGAPGPLWPLPWGALAWAVGFVSSMGSGNPAPGGVCWLQQGQEATCSLVLQTDVTRAE
Sbjct: 1 MRPGAPGPLWPLPWGALAWAVGFVSSMGSGNPAPGGVCWLQQGQEATCSLVLQTDVTRAE 60
Query: 61 CCASGNIDTAWSNLTHPGNKINLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPRCE 120
CCASGNIDTAWSNLTHPGNKINLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPRCE
Sbjct: 61 CCASGNIDTAWSNLTHPGNKINLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPRCE 120
Query: 121 CAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQ 180
CAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQ
Sbjct: 121 CAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQ 180
Query: 181 SCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHA 240
SCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHA
Sbjct: 181 SCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHA 240
Query: 241 GSCAGTPEEPPGGESAEEEENFV 263
GSCAGTPEEPPGGESAEEEENFV
Sbjct: 241 GSCAGTPEEPPGGESAEEEENFV 263
>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
Length = 317
Score = 232 bits (592), Expect = 2e-61
Identities = 102/214 (47%), Positives = 144/214 (67%), Gaps = 4/214 (1%)
Query: 33 APGGVCWLQQGQEATCSLVLQTDVTRAECCASGNIDTAWSNLTHPGNKIN--LLGFLGLV 90
A G CWL+Q + C ++ +T++++ ECC++G + T+W+ N + ++ G
Sbjct: 27 AQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAP 86
Query: 91 HCLPCKDSCDGVECGPGKACRM-LGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELR 149
+C+PCK++C+ V+CGPGK CRM +PRC CAPDCS + + VCG DG TYR+EC L
Sbjct: 87 NCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALL 146
Query: 150 AARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQE 209
ARC+ P+L V Y+GRC+K+C V CP +CVVDQT +A+CV C CP P+S Q
Sbjct: 147 KARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRI-CPEPASSEQY 205
Query: 210 LCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSC 243
LCGN+ VTY S+CH+R+ATC LGRSIG+ + G C
Sbjct: 206 LCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239
Score = 87.8 bits (216), Expect = 9e-18
Identities = 53/157 (33%), Positives = 79/157 (50%), Gaps = 12/157 (7%)
Query: 95 CKDSCDGVECGPGKACRMLGGRPRCECAPDCSGL---PARLQ--VCGSDGATYRDECELR 149
CK +C V C PG + ++ C C+ + PA + +CG+DG TY C LR
Sbjct: 164 CKKTCRDVFC-PGSSTCVVDQTNNAYCVT-CNRICPEPASSEQYLCGNDGVTYSSACHLR 221
Query: 150 AARCRGHPDLSVMYRGRC--RKSCEHVVCPRPQSCVVD-QTGSAHCVVCRAAPCPVPSSP 206
A C + + Y G+C KSCE + C + C+ D + G C +C CP S
Sbjct: 222 KATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDEL-CP-DSKS 279
Query: 207 GQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSC 243
+ +C ++N TY S C M++A C G + V+H+GSC
Sbjct: 280 DEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
Score = 38.1 bits (87), Expect = 0.008
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 167 CRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQ 226
C+++CE+V C + C +++ CV A C + G +CG + TY + C + +
Sbjct: 91 CKETCENVDCGPGKKCRMNKKNKPRCVC--APDCSNITWKGP-VCGLDGKTYRNECALLK 147
Query: 227 ATCFLGRSIGVRHAGSCAGT 246
A C + V++ G C T
Sbjct: 148 ARCKEQPELEVQYQGRCKKT 167
>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
Length = 344
Score = 232 bits (592), Expect = 2e-61
Identities = 102/214 (47%), Positives = 144/214 (67%), Gaps = 4/214 (1%)
Query: 33 APGGVCWLQQGQEATCSLVLQTDVTRAECCASGNIDTAWSNLTHPGNKIN--LLGFLGLV 90
A G CWL+Q + C ++ +T++++ ECC++G + T+W+ N + ++ G
Sbjct: 27 AQAGNCWLRQAKNGRCQVLYKTELSKEECCSTGRLSTSWTEEDVNDNTLFKWMIFNGGAP 86
Query: 91 HCLPCKDSCDGVECGPGKACRM-LGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELR 149
+C+PCK++C+ V+CGPGK CRM +PRC CAPDCS + + VCG DG TYR+EC L
Sbjct: 87 NCIPCKETCENVDCGPGKKCRMNKKNKPRCVCAPDCSNITWKGPVCGLDGKTYRNECALL 146
Query: 150 AARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQE 209
ARC+ P+L V Y+GRC+K+C V CP +CVVDQT +A+CV C CP P+S Q
Sbjct: 147 KARCKEQPELEVQYQGRCKKTCRDVFCPGSSTCVVDQTNNAYCVTCNRI-CPEPASSEQY 205
Query: 210 LCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSC 243
LCGN+ VTY S+CH+R+ATC LGRSIG+ + G C
Sbjct: 206 LCGNDGVTYSSACHLRKATCLLGRSIGLAYEGKC 239
Score = 92.0 bits (227), Expect = 5e-19
Identities = 56/174 (32%), Positives = 86/174 (49%), Gaps = 12/174 (6%)
Query: 95 CKDSCDGVECGPGKACRMLGGRPRCECAPDCSGL---PARLQ--VCGSDGATYRDECELR 149
CK +C V C PG + ++ C C+ + PA + +CG+DG TY C LR
Sbjct: 164 CKKTCRDVFC-PGSSTCVVDQTNNAYCVT-CNRICPEPASSEQYLCGNDGVTYSSACHLR 221
Query: 150 AARCRGHPDLSVMYRGRC--RKSCEHVVCPRPQSCVVD-QTGSAHCVVCRAAPCPVPSSP 206
A C + + Y G+C KSCE + C + C+ D + G C +C CP S
Sbjct: 222 KATCLLGRSIGLAYEGKCIKAKSCEDIQCTGGKKCLWDFKVGRGRCSLCDEL-CP-DSKS 279
Query: 207 GQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPEEPPGGESAEEEE 260
+ +C ++N TY S C M++A C G + V+H+GSC E+ E E+++
Sbjct: 280 DEPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQD 333
Score = 38.1 bits (87), Expect = 0.008
Identities = 22/80 (27%), Positives = 39/80 (48%), Gaps = 3/80 (3%)
Query: 167 CRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQ 226
C+++CE+V C + C +++ CV A C + G +CG + TY + C + +
Sbjct: 91 CKETCENVDCGPGKKCRMNKKNKPRCVC--APDCSNITWKGP-VCGLDGKTYRNECALLK 147
Query: 227 ATCFLGRSIGVRHAGSCAGT 246
A C + V++ G C T
Sbjct: 148 ARCKEQPELEVQYQGRCKKT 167
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 80.5 bits (197), Expect = 1e-15
Identities = 65/225 (28%), Positives = 83/225 (36%), Gaps = 59/225 (26%)
Query: 91 HCLPCKDS---CDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECE 147
H PC + C GV+C G C + G+ CEC CS L VCGSDG TY CE
Sbjct: 457 HQGPCDQAPSPCLGVQCAFGATCAVKNGQAACECLQACSSLYD--PVCGSDGVTYGSACE 514
Query: 148 LRAARCRGHPDLSVMYRGRCRKS--------CE----HVVCPR----------------- 178
L A C ++ V +G C + CE VCP
Sbjct: 515 LEATACTLGREIQVARKGPCDRCGQCRFGALCEAETGRCVCPSECVALAQPVCGSDGHTY 574
Query: 179 PQSCVV-------------------DQTGSAHC---VVCRAAPCPVP---SSPGQELCGN 213
P C++ + G A C VC A C P P +CG+
Sbjct: 575 PSECMLHVHACTHQISLHVASAGPCETCGDAVCAFGAVCSAGQCVCPRCEHPPPGPVCGS 634
Query: 214 NNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPEEPPGGESAEE 258
+ VTY S+C +R+A C I AG C G S E+
Sbjct: 635 DGVTYGSACELREAACLQQTQIEEARAGPCEQAECGSGGSGSGED 679
Score = 75.1 bits (183), Expect = 6e-14
Identities = 45/153 (29%), Positives = 67/153 (43%), Gaps = 11/153 (7%)
Query: 97 DSCDGVECGPGKACRMLG---GRPRCECAPD-CSGLPARLQVCGSDGATYRDECELRAAR 152
D+C G+ CG G C GR C C C + A VCGSD +TY +ECEL+ A+
Sbjct: 170 DACRGMLCGFGAVCEPNAEGPGRASCVCKKSPCPSVVA--PVCGSDASTYSNECELQRAQ 227
Query: 153 CRGHPDLSVMYRGRC--RKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQEL 210
C + ++ RG C R C +V C +C G +C P +P +
Sbjct: 228 CSQQRRIRLLSRGPCGSRDPCSNVTCSFGSTCARSADGLTASCLC---PATCRGAPEGTV 284
Query: 211 CGNNNVTYISSCHMRQATCFLGRSIGVRHAGSC 243
CG++ Y C + + C ++ + G C
Sbjct: 285 CGSDGADYPGECQLLRRACARQENVFKKFDGPC 317
Score = 74.7 bits (182), Expect = 8e-14
Identities = 51/152 (33%), Positives = 67/152 (44%), Gaps = 13/152 (8%)
Query: 96 KDSCDGVECGPGKACRMLGGRPRCEC-APDCSGLPARLQVCGSDGATYRDECELRAARCR 154
+D C C C GRPRC C C G A VC DG TY +C + A CR
Sbjct: 392 RDQCPE-PCRFNAVCLSRRGRPRCSCDRVTCDG--AYRPVCAQDGRTYDSDCWRQQAECR 448
Query: 155 GHPDLSVMYRGRCRKS---CEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELC 211
+ ++G C ++ C V C +C V + G A C +A SS +C
Sbjct: 449 QQRAIPSKHQGPCDQAPSPCLGVQCAFGATCAV-KNGQAACECLQAC-----SSLYDPVC 502
Query: 212 GNNNVTYISSCHMRQATCFLGRSIGVRHAGSC 243
G++ VTY S+C + C LGR I V G C
Sbjct: 503 GSDGVTYGSACELEATACTLGREIQVARKGPC 534
Score = 72.8 bits (177), Expect = 3e-13
Identities = 52/171 (30%), Positives = 72/171 (42%), Gaps = 25/171 (14%)
Query: 94 PCKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARC 153
PC ++C C G C +C C P C P VCGSDG TY CELR A C
Sbjct: 598 PC-ETCGDAVCAFGAVC----SAGQCVC-PRCEHPPPG-PVCGSDGVTYGSACELREAAC 650
Query: 154 RGHPDLSVMYRGRCRKS--------------CEHVVCPRPQSCVVDQTGSAHCVVCRAAP 199
+ G C ++ CE +C R + + D+ VC +
Sbjct: 651 LQQTQIEEARAGPCEQAECGSGGSGSGEDGDCEQELC-RQRGGIWDEDSEDGPCVCDFSC 709
Query: 200 CPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPEEP 250
VP SP +CG++ VTY + C +++A C R + V G+C G P
Sbjct: 710 QSVPGSP---VCGSDGVTYSTECELKKARCESQRGLYVAAQGACRGPTFAP 757
Score = 61.6 bits (148), Expect = 7e-10
Identities = 51/168 (30%), Positives = 71/168 (42%), Gaps = 14/168 (8%)
Query: 94 PCKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPAR-LQVCGSDGATYRDECEL-RAA 151
PC D C G P ++CR+ R E PAR VCG DG TY ++C + R+
Sbjct: 316 PC-DPCQGALPDPSRSCRVNPRTRRPEMLLRPESCPARQAPVCGDDGVTYENDCVMGRSG 374
Query: 152 RCRGHPDLSVMYRGRCRKSCEHVVCPRP---QSCVVDQTGSAHCVVCRAAPCPVPSSPGQ 208
RG L + G+C+ + CP P + + + G C C C P
Sbjct: 375 AARGLL-LQKVRSGQCQGRDQ---CPEPCRFNAVCLSRRGRPRCS-CDRVTCDGAYRP-- 427
Query: 209 ELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPEEPPGGESA 256
+C + TY S C +QA C R+I +H G C P G + A
Sbjct: 428 -VCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQCA 474
Score = 57.0 bits (136), Expect = 2e-08
Identities = 46/165 (27%), Positives = 58/165 (35%), Gaps = 22/165 (13%)
Query: 99 CDGVECGPG------------KACRMLGG-------RPRCECAPDCSGLPARLQVCGSDG 139
C+ ECG G + CR GG C C C +P VCGSDG
Sbjct: 664 CEQAECGSGGSGSGEDGDCEQELCRQRGGIWDEDSEDGPCVCDFSCQSVPGS-PVCGSDG 722
Query: 140 ATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCP-RPQSCVVDQTGSAHCVVCRAA 198
TY ECEL+ ARC L V +G CR + P P C G + A
Sbjct: 723 VTYSTECELKKARCESQRGLYVAAQGACRGPTFAPLPPVAPLHCAQTPYGCCQDNITAAR 782
Query: 199 PCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSC 243
+ P C N + +Y +C C +G C
Sbjct: 783 GVGLAGCPSACQC-NPHGSYGGTCDPATGQCSCRPGVGGLRCDRC 826
Score = 54.3 bits (129), Expect = 1e-07
Identities = 49/192 (25%), Positives = 72/192 (37%), Gaps = 54/192 (28%)
Query: 95 CKDSCDGVECGP----GKACRMLGGRPRCECAPDCSGLPARLQVC-------------GS 137
C +C +C P G C G+ C C P GL R C G
Sbjct: 789 CPSAC---QCNPHGSYGGTCDPATGQ--CSCRPGVGGL--RCDRCEPGFWNFRGIVTDGR 841
Query: 138 DGAT---------YRDECELRAARCRGHPDLSVMYRGRCRK-----------------SC 171
G T RD+CE C P ++ G+C +C
Sbjct: 842 SGCTPCSCDPQGAVRDDCEQMTGLCSCKPGVAGPKCGQCPDGRALGPAGCEADASAPATC 901
Query: 172 EHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFL 231
+ C CV +++GSAHCV C CP ++ ++CG++ VTY + C ++ C
Sbjct: 902 AEMRCEFGARCV-EESGSAHCV-CPMLTCPEANAT--KVCGSDGVTYGNECQLKTIACRQ 957
Query: 232 GRSIGVRHAGSC 243
G I ++ G C
Sbjct: 958 GLQISIQSLGPC 969
Score = 52.4 bits (124), Expect = 4e-07
Identities = 31/109 (28%), Positives = 44/109 (40%)
Query: 98 SCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHP 157
+C + C G C G C C +VCGSDG TY +EC+L+ CR
Sbjct: 900 TCAEMRCEFGARCVEESGSAHCVCPMLTCPEANATKVCGSDGVTYGNECQLKTIACRQGL 959
Query: 158 DLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSP 206
+S+ G C+++ P S V G A P +P +P
Sbjct: 960 QISIQSLGPCQEAVAPSTHPTSASVTVTTPGLLLSQALPAPPGALPLAP 1008
>gi|29568105 transmembrane protein with EGF-like and two
follistatin-like domains 1 [Homo sapiens]
Length = 380
Score = 68.6 bits (166), Expect = 5e-12
Identities = 46/171 (26%), Positives = 70/171 (40%), Gaps = 28/171 (16%)
Query: 99 CDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPD 158
CD C G C+ G +C C C + VCGS+G TY++EC LR A C+ +
Sbjct: 77 CDESSCKYGGVCKEDGDGLKCACQFQCH--TNYIPVCGSNGDTYQNECFLRRAACKHQKE 134
Query: 159 LSVMYRGRC---------------------RKSCEHVVCPRPQSCVVDQTGSAHCVVCRA 197
++V+ RG C RK + C C D+ VC
Sbjct: 135 ITVIARGPCYSDNGSGSGEGEEEGSGAEVHRKHSKCGPCKYKAEC--DEDAENVGCVCNI 192
Query: 198 APCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPE 248
+P +C ++ +Y + C +R+A+C I +RH G C T +
Sbjct: 193 DCSGYSFNP---VCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDD 240
Score = 32.0 bits (71), Expect = 0.57
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 5/53 (9%)
Query: 210 LCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSC-----AGTPEEPPGGESAE 257
+CG+N TY + C +R+A C + I V G C +G+ E G AE
Sbjct: 110 VCGSNGDTYQNECFLRRAACKHQKEITVIARGPCYSDNGSGSGEGEEEGSGAE 162
>gi|190194423 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 59.3 bits (142), Expect = 3e-09
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 170 SCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATC 229
SC C R C DQ G HCV CP P+ P ++CG +N TY SSCH+ C
Sbjct: 432 SCMSFQCKRGHICKADQQGKPHCVCQDPVTCP-PTKPLDQVCGTDNQTYASSCHLFATKC 490
Query: 230 FL-----GRSIGVRHAGSCAGTP 247
L G + + + G+C P
Sbjct: 491 RLEGTKKGHQLQLDYFGACKSIP 513
Score = 48.1 bits (113), Expect = 8e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 10/81 (12%)
Query: 97 DSCDGVECGPGKACRM-LGGRPRCECAPDCSGLPARL--QVCGSDGATYRDECELRAARC 153
DSC +C G C+ G+P C C + P + QVCG+D TY C L A +C
Sbjct: 431 DSCMSFQCKRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKC 490
Query: 154 R------GHPDLSVMYRGRCR 168
R GH L + Y G C+
Sbjct: 491 RLEGTKKGH-QLQLDYFGACK 510
>gi|190341024 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 59.3 bits (142), Expect = 3e-09
Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 6/83 (7%)
Query: 170 SCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATC 229
SC C R C DQ G HCV CP P+ P ++CG +N TY SSCH+ C
Sbjct: 432 SCMSFQCKRGHICKADQQGKPHCVCQDPVTCP-PTKPLDQVCGTDNQTYASSCHLFATKC 490
Query: 230 FL-----GRSIGVRHAGSCAGTP 247
L G + + + G+C P
Sbjct: 491 RLEGTKKGHQLQLDYFGACKSIP 513
Score = 48.1 bits (113), Expect = 8e-06
Identities = 29/81 (35%), Positives = 38/81 (46%), Gaps = 10/81 (12%)
Query: 97 DSCDGVECGPGKACRM-LGGRPRCECAPDCSGLPARL--QVCGSDGATYRDECELRAARC 153
DSC +C G C+ G+P C C + P + QVCG+D TY C L A +C
Sbjct: 431 DSCMSFQCKRGHICKADQQGKPHCVCQDPVTCPPTKPLDQVCGTDNQTYASSCHLFATKC 490
Query: 154 R------GHPDLSVMYRGRCR 168
R GH L + Y G C+
Sbjct: 491 RLEGTKKGH-QLQLDYFGACK 510
>gi|5901956 follistatin-like 1 precursor [Homo sapiens]
Length = 308
Score = 55.1 bits (131), Expect = 6e-08
Identities = 31/85 (36%), Positives = 39/85 (45%), Gaps = 9/85 (10%)
Query: 99 CDGVECGPGKACRMLG-GRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHP 157
C V CG G+ C + G P C C C P + VCGS+G TY + CEL C
Sbjct: 31 CANVFCGAGRECAVTEKGEPTCLCIEQCK--PHKRPVCGSNGKTYLNHCELHRDACLTGS 88
Query: 158 DLSVMYRGRCRK------SCEHVVC 176
+ V Y G C++ S VVC
Sbjct: 89 KIQVDYDGHCKEKKSVSPSASPVVC 113
Score = 43.9 bits (102), Expect = 1e-04
Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 5/75 (6%)
Query: 169 KSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQAT 228
K C +V C + C V + G C+ C P +CG+N TY++ C + +
Sbjct: 29 KICANVFCGAGRECAVTEKGEPTCLCIEQ--CKPHKRP---VCGSNGKTYLNHCELHRDA 83
Query: 229 CFLGRSIGVRHAGSC 243
C G I V + G C
Sbjct: 84 CLTGSKIQVDYDGHC 98
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 53.5 bits (127), Expect = 2e-07
Identities = 41/165 (24%), Positives = 65/165 (39%), Gaps = 26/165 (15%)
Query: 99 CDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPD 158
CD C C +G C C C+ + VCGS+G +Y++EC LR A C+ +
Sbjct: 69 CDTNTCKFDGECLRIGDTVTCVCQFKCNN--DYVPVCGSNGESYQNECYLRQAACKQQSE 126
Query: 159 LSVMYRGRC------------RKSCEHVVCPRPQSCVVDQTGSAHC--------VVCRAA 198
+ V+ G C + +C + Q G A C VC
Sbjct: 127 ILVVSEGSCATDAGSGSGDGVHEGSGETSQKETSTCDICQFG-AECDEDAEDVWCVCNID 185
Query: 199 PCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSC 243
+P LC ++ +Y ++C +++A+C I V G C
Sbjct: 186 CSQTNFNP---LCASDGKSYDNACQIKEASCQKQEKIEVMSLGRC 227
Score = 40.0 bits (92), Expect = 0.002
Identities = 18/50 (36%), Positives = 27/50 (54%), Gaps = 1/50 (2%)
Query: 119 CECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCR 168
C C DCS +C SDG +Y + C+++ A C+ + VM GRC+
Sbjct: 180 CVCNIDCSQTNFN-PLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQ 228
Score = 34.7 bits (78), Expect = 0.087
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 7/57 (12%)
Query: 210 LCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCA-------GTPEEPPGGESAEEE 259
+CG+N +Y + C++RQA C I V GSCA G GE++++E
Sbjct: 102 VCGSNGESYQNECYLRQAACKQQSEILVVSEGSCATDAGSGSGDGVHEGSGETSQKE 158
>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
Length = 457
Score = 48.9 bits (115), Expect = 4e-06
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 120 ECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCR 168
+C+ DC+G P + +C SDG T+ CE + A+C+ P L + YRG C+
Sbjct: 39 DCSLDCAGSPQK-PLCASDGRTFLSRCEFQRAKCK-DPQLEIAYRGNCK 85
>gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens]
Length = 303
Score = 48.1 bits (113), Expect = 8e-06
Identities = 23/82 (28%), Positives = 37/82 (45%), Gaps = 5/82 (6%)
Query: 171 CEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCF 230
C++ C + C +D+ + CV CP P +++C N+N T+ SSCH C
Sbjct: 72 CQNHHCKHGKVCELDENNTPMCVCQDPTSCPAPIGEFEKVCSNDNKTFDSSCHFFATKCT 131
Query: 231 L-----GRSIGVRHAGSCAGTP 247
L G + + + G C P
Sbjct: 132 LEGTKKGHKLHLDYIGPCKYIP 153
Score = 35.0 bits (79), Expect = 0.067
Identities = 24/84 (28%), Positives = 36/84 (42%), Gaps = 13/84 (15%)
Query: 96 KDSCDGVECGPGKACRM-LGGRPRCECAPDCSGLPARL----QVCGSDGATYRDECELRA 150
++ C C GK C + P C C D + PA + +VC +D T+ C A
Sbjct: 69 ENPCQNHHCKHGKVCELDENNTPMCVCQ-DPTSCPAPIGEFEKVCSNDNKTFDSSCHFFA 127
Query: 151 ARC------RGHPDLSVMYRGRCR 168
+C +GH L + Y G C+
Sbjct: 128 TKCTLEGTKKGH-KLHLDYIGPCK 150
>gi|4504619 insulin-like growth factor binding protein 7 [Homo
sapiens]
Length = 282
Score = 46.2 bits (108), Expect = 3e-05
Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 15/112 (13%)
Query: 104 CGPGKAC-----RMLGGRPRCECAPDCSGL---PARLQVCGSDGATYRDECELRA----A 151
C PG C R G P SG+ +R VCGSDG TY C+LRA A
Sbjct: 81 CAPGMECVKSRKRRKGKAGAAAGGPGVSGVCVCKSRYPVCGSDGTTYPSGCQLRAASQRA 140
Query: 152 RCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVP 203
RG ++ + +G C + V P+ + + TG+ + C P P
Sbjct: 141 ESRGEKAITQVSKGTCEQGPSIVTPPKD---IWNVTGAQVYLSCEVIGIPTP 189
Score = 30.4 bits (67), Expect = 1.6
Identities = 39/166 (23%), Positives = 57/166 (34%), Gaps = 40/166 (24%)
Query: 74 LTHPGNKINLLGFLGLVHCL-PCKDSCDGVECGPGK----------ACRMLGGRPRCECA 122
+ P + LLG GL+ L P S CGP + C + R C C
Sbjct: 1 MERPSLRALLLGAAGLLLLLLPLSSSSSSDTCGPCEPASCPPLPPLGCLLGETRDACGCC 60
Query: 123 PDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSC 182
P C+ + CG GA R C P + + + RK P
Sbjct: 61 PMCAR--GEGEPCGGGGAG-RGYCA---------PGMECVKSRKRRKGKAGAAAGGP--- 105
Query: 183 VVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQAT 228
G + VC++ +CG++ TY S C +R A+
Sbjct: 106 -----GVSGVCVCKSR---------YPVCGSDGTTYPSGCQLRAAS 137
>gi|54792136 follistatin-like 4 [Homo sapiens]
Length = 842
Score = 45.4 bits (106), Expect = 5e-05
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 98 SCDGVECGPGKACRMLG--GRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRG 155
SC C G C + G P C+C C P+ + VCGSDG Y + C+L A C
Sbjct: 64 SCGKKFCSRGSRCVLSRKTGEPECQCLEACR--PSYVPVCGSDGRFYENHCKLHRAACLL 121
Query: 156 HPDLSVMYRGRC 167
++V++ C
Sbjct: 122 GKRITVIHSKDC 133
Score = 41.2 bits (95), Expect = 0.001
Identities = 25/76 (32%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 170 SCEHVVCPRPQSCVVDQ-TGSAHCVVCRAA-PCPVPSSPGQELCGNNNVTYISSCHMRQA 227
SC C R CV+ + TG C A P VP +CG++ Y + C + +A
Sbjct: 64 SCGKKFCSRGSRCVLSRKTGEPECQCLEACRPSYVP------VCGSDGRFYENHCKLHRA 117
Query: 228 TCFLGRSIGVRHAGSC 243
C LG+ I V H+ C
Sbjct: 118 ACLLGKRITVIHSKDC 133
>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
[Homo sapiens]
Length = 435
Score = 45.4 bits (106), Expect = 5e-05
Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 34/166 (20%)
Query: 102 VECGPGKACRMLGGRPRC-ECAPDCSGLPARLQ---VCGSDGATYRDECELRAARCRGHP 157
V+ P + R G R + P C+ +R Q +C SDG +Y CE + A+CR P
Sbjct: 19 VQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCR-DP 77
Query: 158 DLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQEL----CGN 213
L V++RGRC+ G + C + RA P + + CG
Sbjct: 78 TLGVVHRGRCK-----------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGE 120
Query: 214 NNVTYISSCHMRQATCFLGRSIGVRHAGS--------CAGTPEEPP 251
+ CH C+ G +GS C+G+ + P
Sbjct: 121 DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKP 166
>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
[Homo sapiens]
Length = 434
Score = 45.4 bits (106), Expect = 5e-05
Identities = 42/166 (25%), Positives = 64/166 (38%), Gaps = 34/166 (20%)
Query: 102 VECGPGKACRMLGGRPRC-ECAPDCSGLPARLQ---VCGSDGATYRDECELRAARCRGHP 157
V+ P + R G R + P C+ +R Q +C SDG +Y CE + A+CR P
Sbjct: 19 VQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCR-DP 77
Query: 158 DLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQEL----CGN 213
L V++RGRC+ G + C + RA P + + CG
Sbjct: 78 TLGVVHRGRCK-----------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGE 120
Query: 214 NNVTYISSCHMRQATCFLGRSIGVRHAGS--------CAGTPEEPP 251
+ CH C+ G +GS C+G+ + P
Sbjct: 121 DGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPVCSGSVTDKP 166
>gi|16751923 WAP, follistatin/kazal, immunoglobulin, kunitz and
netrin domain containing 1 precursor [Homo sapiens]
Length = 548
Score = 44.3 bits (103), Expect = 1e-04
Identities = 32/113 (28%), Positives = 46/113 (40%), Gaps = 10/113 (8%)
Query: 98 SCDGVECGP-GKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGH 156
SC+G C G C + G+P C C C P+ C SDG TY + C + A C
Sbjct: 92 SCEGFVCPQQGSDCDIWDGQPVCRCRDRCEKEPS--FTCASDGLTYYNRCYMDAEACLRG 149
Query: 157 PDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQE 209
L ++ C+HV+ P S +T + P + SSP +
Sbjct: 150 LHLHIV-------PCKHVLSWPPSSPGPPETTARPTPGAAPVPPALYSSPSPQ 195
Score = 31.6 bits (70), Expect = 0.74
Identities = 36/135 (26%), Positives = 47/135 (34%), Gaps = 17/135 (12%)
Query: 121 CAPDCSGLPARLQVCGSDGATYRDECELR---AARCRGHPDLSVMYRGRCRKSCEHVVCP 177
C +CS R Q C + + C L AAR G P SCE VCP
Sbjct: 49 CERECS----RDQDCAAAEKCCINVCGLHSCVAARFPGSPAAPTT-----AASCEGFVCP 99
Query: 178 RPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGV 237
+ S G C CR PS C ++ +TY + C+M C G + +
Sbjct: 100 QQGSDCDIWDGQPVCR-CRDRCEKEPSFT----CASDGLTYYNRCYMDAEACLRGLHLHI 154
Query: 238 RHAGSCAGTPEEPPG 252
P PG
Sbjct: 155 VPCKHVLSWPPSSPG 169
>gi|190358524 follistatin-like 5 isoform c [Homo sapiens]
Length = 837
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 98 SCDGVECGPGKACRMLGGRPRCECAPDCSGLPAR--LQVCGSDGATYRDECELRAARCRG 155
SC+ CG G+ C + ECA C L R VCGSDG Y + CE+ A C
Sbjct: 63 SCENKYCGLGRHCVTSRETGQAECA--CMDLCKRHYKPVCGSDGEFYENHCEVHRAACLK 120
Query: 156 HPDLSVMYRGRC 167
+++++ C
Sbjct: 121 KQKITIVHNEDC 132
Score = 35.4 bits (80), Expect = 0.051
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 170 SCEHVVCPRPQSCVVD-QTGSAHCV---VCRAAPCPVPSSPGQELCGNNNVTYISSCHMR 225
SCE+ C + CV +TG A C +C+ PV CG++ Y + C +
Sbjct: 63 SCENKYCGLGRHCVTSRETGQAECACMDLCKRHYKPV--------CGSDGEFYENHCEVH 114
Query: 226 QATCFLGRSIGVRHAGSC 243
+A C + I + H C
Sbjct: 115 RAACLKKQKITIVHNEDC 132
>gi|190358522 follistatin-like 5 isoform b [Homo sapiens]
Length = 846
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 98 SCDGVECGPGKACRMLGGRPRCECAPDCSGLPAR--LQVCGSDGATYRDECELRAARCRG 155
SC+ CG G+ C + ECA C L R VCGSDG Y + CE+ A C
Sbjct: 63 SCENKYCGLGRHCVTSRETGQAECA--CMDLCKRHYKPVCGSDGEFYENHCEVHRAACLK 120
Query: 156 HPDLSVMYRGRC 167
+++++ C
Sbjct: 121 KQKITIVHNEDC 132
Score = 35.4 bits (80), Expect = 0.051
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 170 SCEHVVCPRPQSCVVD-QTGSAHCV---VCRAAPCPVPSSPGQELCGNNNVTYISSCHMR 225
SCE+ C + CV +TG A C +C+ PV CG++ Y + C +
Sbjct: 63 SCENKYCGLGRHCVTSRETGQAECACMDLCKRHYKPV--------CGSDGEFYENHCEVH 114
Query: 226 QATCFLGRSIGVRHAGSC 243
+A C + I + H C
Sbjct: 115 RAACLKKQKITIVHNEDC 132
>gi|190358520 follistatin-like 5 isoform a [Homo sapiens]
Length = 847
Score = 43.1 bits (100), Expect = 2e-04
Identities = 24/72 (33%), Positives = 34/72 (47%), Gaps = 4/72 (5%)
Query: 98 SCDGVECGPGKACRMLGGRPRCECAPDCSGLPAR--LQVCGSDGATYRDECELRAARCRG 155
SC+ CG G+ C + ECA C L R VCGSDG Y + CE+ A C
Sbjct: 64 SCENKYCGLGRHCVTSRETGQAECA--CMDLCKRHYKPVCGSDGEFYENHCEVHRAACLK 121
Query: 156 HPDLSVMYRGRC 167
+++++ C
Sbjct: 122 KQKITIVHNEDC 133
Score = 35.4 bits (80), Expect = 0.051
Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 12/78 (15%)
Query: 170 SCEHVVCPRPQSCVVD-QTGSAHCV---VCRAAPCPVPSSPGQELCGNNNVTYISSCHMR 225
SCE+ C + CV +TG A C +C+ PV CG++ Y + C +
Sbjct: 64 SCENKYCGLGRHCVTSRETGQAECACMDLCKRHYKPV--------CGSDGEFYENHCEVH 115
Query: 226 QATCFLGRSIGVRHAGSC 243
+A C + I + H C
Sbjct: 116 RAACLKKQKITIVHNEDC 133
>gi|93102379 low density lipoprotein-related protein 1B precursor
[Homo sapiens]
Length = 4599
Score = 42.4 bits (98), Expect = 4e-04
Identities = 44/175 (25%), Positives = 56/175 (32%), Gaps = 39/175 (22%)
Query: 95 CKDSC-DGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAAR- 152
C + C +G C P GRP C CA +G VC D C + A
Sbjct: 4253 CSNYCQNGGTCVPSVL-----GRPTCSCALGFTGPNCGKTVC-EDFCQNGGTCIVTAGNQ 4306
Query: 153 --CRGHPDLSVMYRG-RCRKSCEHVVCPRPQSCVVDQTGSAHCVV--------------- 194
C P+ Y G RC+ H C +SC + GS CV
Sbjct: 4307 PYCHCQPE----YTGDRCQYYVCHHYCVNSESCTIGDDGSVECVCPTRYEGPKCEVDKCV 4362
Query: 195 -CRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTPE 248
C C + C N SSC + C+ G G+C PE
Sbjct: 4363 RCHGGHCIINKDSEDIFCNCTNGKIASSCQLCDGYCYNG--------GTCQLDPE 4409
Score = 33.9 bits (76), Expect = 0.15
Identities = 31/109 (28%), Positives = 41/109 (37%), Gaps = 28/109 (25%)
Query: 92 CLPCKDSCDGVECGPGKACRMLGGRPRCE-CAPDCSGLPARLQVCGSDGATYRDECELRA 150
C+P K CDG E C+ CE +P CS +R +C SDG C +
Sbjct: 3565 CIPAKWKCDGHE-----DCKYGEDEKSCEPASPTCS---SREYICASDG------CISAS 3610
Query: 151 ARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQ---TGSAHCVVCR 196
+C G D C + + C C DQ AHC+ R
Sbjct: 3611 LKCNGEYD--------CADGSDEMDC--VTECKEDQFRCKNKAHCIPIR 3649
Score = 30.4 bits (67), Expect = 1.6
Identities = 21/69 (30%), Positives = 25/69 (36%), Gaps = 18/69 (26%)
Query: 96 KDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVC--------GSDGATYRDECE 147
+D CD CGP P+ CA D S ++C GSD DEC
Sbjct: 1128 EDDCDSFLCGP----------PKHPCANDTSVCLQPEKLCNGKKDCPDGSDEGYLCDECS 1177
Query: 148 LRAARCRGH 156
L C H
Sbjct: 1178 LNNGGCSNH 1186
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 42.0 bits (97), Expect = 5e-04
Identities = 55/213 (25%), Positives = 75/213 (35%), Gaps = 66/213 (30%)
Query: 36 GVCWLQQGQEATCSLVLQTDVTRAECCASGNIDTAWSNLTHPGNKINLLGFLGLVHCLPC 95
G CWL+ QE+ C + LQ R+ECCA+ + AW + PC
Sbjct: 810 GTCWLKI-QESRCEVNLQGASLRSECCAT--LGAAWGS--------------------PC 846
Query: 96 KDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRG 155
+ RCE P C+ AR+ G T D E C
Sbjct: 847 E---------------------RCEIDPACARGFARM-----TGVTCDDVNE-----CES 875
Query: 156 HPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGNNN 215
P V GRC + C P+ ++D +G CV R PC + ++ CG
Sbjct: 876 FP--GVCPNGRCVNTAGSFRCECPEGLMLDASGRL-CVDVRLEPCFLRWD--EDECG--- 927
Query: 216 VTYISSCHMRQATCFLGRSIGVRHAGSCAGTPE 248
VT M C +G GV C P+
Sbjct: 928 VTLPGKYRMDVCCCSIGAVWGV----ECEACPD 956
Score = 35.4 bits (80), Expect = 0.051
Identities = 61/241 (25%), Positives = 79/241 (32%), Gaps = 50/241 (20%)
Query: 47 TCSLVLQTDVTRAECCASGNIDTAWSNLTH-------PGNKI----NLLGFLGLVHC-LP 94
TC L +VTR CC S NI AW+ P +I GFL +H P
Sbjct: 1660 TCQNELAFNVTRKMCCCSYNIGQAWNRPCEACPTPISPDYQILCGNQAPGFLTDIHTGKP 1719
Query: 95 CK-DSCDGVE--CGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAA 151
D C + C G +G RCEC P + L C DEC R +
Sbjct: 1720 LDIDECGEIPAICANGICINQIGSF-RCEC-PAGFNYNSILLACED-----VDECGSRES 1772
Query: 152 RCRGHPD---LSVMYRGRC--------------RKSCEHVVCPRPQSCVVDQTGSAHCVV 194
C+ + D + YR +C R C + +D GS C+
Sbjct: 1773 PCQQNADCINIPGSYRCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLC 1832
Query: 195 CRA-------APCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTP 247
R C ++ CGN I + CF G V H G C
Sbjct: 1833 HRGFQASADQTLCMDIDECDRQPCGNGTCKNIIGSY--NCLCFPG--FVVTHNGDCVDFD 1888
Query: 248 E 248
E
Sbjct: 1889 E 1889
Score = 35.0 bits (79), Expect = 0.067
Identities = 56/238 (23%), Positives = 75/238 (31%), Gaps = 62/238 (26%)
Query: 36 GVCWLQQGQEA----TCSLVLQTDVTRAECCASGNIDTAWSNLTH--------------P 77
G C+L+ +CS + VTRA CC S + AW N P
Sbjct: 1490 GNCFLETHDRGDSGISCSAEIGVGVTRASCCCS--LGRAWGNPCELCPMANTTEYRTLCP 1547
Query: 78 G------NKINLLGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPRCECAP-------- 123
G N+I ++ + C C G + C G +CEC P
Sbjct: 1548 GGEGFQPNRITVI-LEDIDECQELPGLCQGGD------CVNTFGSFQCECPPGYHLSEHT 1600
Query: 124 ----DCSGLPARLQVCG-----SDGATYRDECELRAARCRGHPDLSVM--------YRGR 166
D +CG + Y C + G + M Y G
Sbjct: 1601 RICEDIDECSTHSGICGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGT 1660
Query: 167 CRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPG-QELCGNNNVTYISSCH 223
C+ V R C G A C A CP P SP Q LCGN +++ H
Sbjct: 1661 CQNELAFNV-TRKMCCCSYNIGQAWNRPCEA--CPTPISPDYQILCGNQAPGFLTDIH 1715
Score = 32.3 bits (72), Expect = 0.43
Identities = 38/144 (26%), Positives = 53/144 (36%), Gaps = 16/144 (11%)
Query: 112 MLGGRPRCECAPDCSGLPARLQVCGSDGATYRDEC---ELRAARCRG---HPDLSVMYRG 165
M GG+ R + A + +G P R++ GS G A C G P S
Sbjct: 26 MAGGQGRWDGALEAAG-PGRVRRRGSPGILQGPNVCGSRFHAYCCPGWRTFPGRSQCVVP 84
Query: 166 RCRKSCEHVVCPRPQSCV-VDQTGSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHM 224
CR++C C +P C D T + C V R + C V G G + + C
Sbjct: 85 ICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCL-----CQK 139
Query: 225 RQATCFLGRSI---GVRHAGSCAG 245
G+ I G + G C G
Sbjct: 140 GYTGTVCGQPICDRGCHNGGRCIG 163
Score = 29.3 bits (64), Expect = 3.7
Identities = 25/94 (26%), Positives = 29/94 (30%), Gaps = 15/94 (15%)
Query: 107 GKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGR 166
G C+ L G C C P LP + C D C PDL V GR
Sbjct: 2222 GMECKNLIGTFACVCPPGMRPLPGSGEGCTDDN------------ECHAQPDLCV--NGR 2267
Query: 167 CRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPC 200
C + C + T C R PC
Sbjct: 2268 CVNTAGSFRCDCDEGFQPSPT-LTECHDIRQGPC 2300
Score = 28.1 bits (61), Expect = 8.2
Identities = 40/185 (21%), Positives = 59/185 (31%), Gaps = 49/185 (26%)
Query: 84 LGFLGLVHCLPCKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYR 143
L F G ++C+ + G CG G ++GG C CA P + C
Sbjct: 2117 LDFTG-INCVDTDECSVGHPCGQGTCTNVIGGF-ECACADGFE--PGLMMTCED-----I 2167
Query: 144 DECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGS-------------- 189
DEC L C RC + +C P + + G+
Sbjct: 2168 DECSLNPLLC----------AFRCHNTEGSYLCTCPAGYTLREDGAMCRDVDECADGQQD 2217
Query: 190 --AHCVVCR------AAPCPVPSSP---GQELCGNNNVTYISSCHMRQATCFLGRSIGVR 238
A + C+ A CP P E C ++N CH + C GR +
Sbjct: 2218 CHARGMECKNLIGTFACVCPPGMRPLPGSGEGCTDDN-----ECHAQPDLCVNGRCVNTA 2272
Query: 239 HAGSC 243
+ C
Sbjct: 2273 GSFRC 2277
>gi|7657453 serine peptidase inhibitor, Kazal type 4 [Homo sapiens]
Length = 86
Score = 42.0 bits (97), Expect = 5e-04
Identities = 22/54 (40%), Positives = 31/54 (57%), Gaps = 5/54 (9%)
Query: 117 PRCEC---APDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRC 167
P CE +P CS + VCG+DG TY +EC+L AR + D+ +M G+C
Sbjct: 35 PICEHMVESPTCSQMSNL--VCGTDGLTYTNECQLCLARIKTKQDIQIMKDGKC 86
>gi|28212222 WFIKKN2 protein [Homo sapiens]
Length = 576
Score = 41.6 bits (96), Expect = 7e-04
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 93 LPCKDSCDGVEC-GPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAA 151
+P + +CD C G C + G+P C+C C P+ C SDG TY + C + A
Sbjct: 105 MPKEATCDHFMCLQQGSECDIWDGQPVCKCKDRCEKEPSF--TCASDGLTYYNRCYMDAE 162
Query: 152 RCRGHPDLSVM 162
C L+V+
Sbjct: 163 ACSKGITLAVV 173
>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan 1 precursor [Homo sapiens]
Length = 439
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 4/70 (5%)
Query: 188 GSAHCVVCRAAPCPVPSSPGQELCGNNNVTYISSCHMRQATCFLGRSIGVRHAGSCAGTP 247
G ++ V C+ PCPV S +CG++ +Y S C + C G+S+ G C P
Sbjct: 129 GPSNLVKCK--PCPVAQSA--MVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPCPCLP 184
Query: 248 EEPPGGESAE 257
E P AE
Sbjct: 185 EPEPPKHKAE 194
Score = 34.3 bits (77), Expect = 0.11
Identities = 25/102 (24%), Positives = 34/102 (33%), Gaps = 30/102 (29%)
Query: 94 PCKDSCDGVECGPGKAC----------------------------RMLGGRPRCECAPDC 125
P KD C V+C P K C +G +C P
Sbjct: 81 PSKDPCLKVKCSPHKVCVTQDYQTALCVSRKHLLPRQKKGNVAQKHWVGPSNLVKCKP-- 138
Query: 126 SGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRC 167
+ VCGSDG +Y +C+L C L+ + G C
Sbjct: 139 CPVAQSAMVCGSDGHSYTSKCKLEFHACSTGKSLATLCDGPC 180
>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
sapiens]
Length = 278
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/109 (35%), Positives = 43/109 (39%), Gaps = 12/109 (11%)
Query: 101 GVECGPGKACRMLGGRPRCECAPDCSGLPARLQ---VCGSDGATYRDECELRAA---RCR 154
G CGPG C AP+ +GL Q VCGSDG +Y C LR R
Sbjct: 82 GGRCGPGLVC----ASQAAGAAPEGTGLCVCAQRGTVCGSDGRSYPSVCALRLRARHTPR 137
Query: 155 GHP-DLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPV 202
HP L G C + VV PR V C V RA P PV
Sbjct: 138 AHPGHLHKARDGPCEFAPVVVVPPRSVHNVTGAQVGLSCEV-RAVPTPV 185
>gi|225690544 keratin associated protein 4-11 [Homo sapiens]
Length = 195
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/129 (28%), Positives = 49/129 (37%), Gaps = 16/129 (12%)
Query: 92 CLP--CKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELR 149
C P C SC +C C+ RPRC C C R C S + R +C +
Sbjct: 75 CRPSCCVSSCCKPQCCQSMCCQPTCCRPRC-CISSC----CRPSCCVS--SCCRPQC-CQ 126
Query: 150 AARCRG---HPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHC-VVCRAAPCPVPSS 205
+ C+ HP S+ CR SC C RP C+ G C C C + S
Sbjct: 127 SVCCQPTCCHPSCSIS--SCCRPSCCESSCCRPCCCLRPVCGRVSCHTTCYRPTCVISSC 184
Query: 206 PGQELCGNN 214
P C ++
Sbjct: 185 PRPLCCASS 193
Score = 33.9 bits (76), Expect = 0.15
Identities = 34/129 (26%), Positives = 49/129 (37%), Gaps = 5/129 (3%)
Query: 95 CKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCR 154
C+++C C CR RP C C C VC R C + + CR
Sbjct: 20 CQETCCRPSCCETTCCRTTYCRPSC-CVSSCCRPQCCQSVC-CQPTCCRPRCCISSC-CR 76
Query: 155 GHPDLSVMYRGRCRKS-CEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVPSSPGQELCGN 213
+S + +C +S C C RP+ C+ + CV P S Q C +
Sbjct: 77 PSCCVSSCCKPQCCQSMCCQPTCCRPRCCISSCCRPSCCVSSCCRPQCCQSVCCQPTCCH 136
Query: 214 NNVTYISSC 222
+ + ISSC
Sbjct: 137 PSCS-ISSC 144
>gi|169212028 PREDICTED: keratin-associated protein 9-2-like 2-like
[Homo sapiens]
Length = 160
Score = 40.8 bits (94), Expect = 0.001
Identities = 32/129 (24%), Positives = 42/129 (32%), Gaps = 15/129 (11%)
Query: 92 CLP--CKDSCDGVECGP----GKACRMLGGRPRCE---CAPDCSGLPARLQVCGSDGATY 142
C P C SC C P CR +P C C P C P +C
Sbjct: 38 CQPSCCVSSCCQPYCHPTCCQNTCCRTTCCQPTCVTSCCQPSCCSTPCYQPICCGSSCCG 97
Query: 143 RDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPV 202
+ C + C + +Y CR++C H C+ GS+ C C C V
Sbjct: 98 QTSC---GSSCGQSSSCAPVY---CRRTCYHPTTVCLPGCLNQSCGSSCCQPCYCPACCV 151
Query: 203 PSSPGQELC 211
S C
Sbjct: 152 SSCCQHSCC 160
>gi|118600977 C3 and PZP-like, alpha-2-macroglobulin domain containing
8 [Homo sapiens]
Length = 1932
Score = 40.8 bits (94), Expect = 0.001
Identities = 24/54 (44%), Positives = 24/54 (44%), Gaps = 6/54 (11%)
Query: 103 ECGPGKACRMLGGRPRCECAPDCS--GLPARLQVCGSDGATYRDECELRAARCR 154
E GP A RC C DC G P VCGSDG Y C LR A CR
Sbjct: 1741 ESGPAVAPEEGAAIARCGCDHDCGAQGNP----VCGSDGVVYASACRLREAACR 1790
Score = 31.2 bits (69), Expect = 0.96
Identities = 10/23 (43%), Positives = 16/23 (69%)
Query: 207 GQELCGNNNVTYISSCHMRQATC 229
G +CG++ V Y S+C +R+A C
Sbjct: 1767 GNPVCGSDGVVYASACRLREAAC 1789
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 39.7 bits (91), Expect = 0.003
Identities = 29/114 (25%), Positives = 42/114 (36%), Gaps = 16/114 (14%)
Query: 108 KACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMY---- 163
+ C + GGR +C C P +G G G + C G+ D ++++
Sbjct: 1926 EGCVLRGGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCD 1985
Query: 164 --RGRCRKSCEHVVCPRPQSCVVDQTGSA----HCVVCRAAPCPVPSSPGQELC 211
G CR H PR + C G+A +C C PC G E C
Sbjct: 1986 PLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPC------GTEAC 2033
Score = 37.4 bits (85), Expect = 0.013
Identities = 39/128 (30%), Positives = 52/128 (40%), Gaps = 18/128 (14%)
Query: 85 GFLGLVHCLPCKDSCDGV---ECGPGKA---CRMLGGRPRCE-CAPDCSGLPARLQVCG- 136
GF G C PC+ S GV C P CR+ C+ CAP P Q+CG
Sbjct: 532 GFYG-PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPL-CQLCGC 589
Query: 137 SDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCV--- 193
S T + C+ A RC P+ + + RCR P Q+C D G+ +
Sbjct: 590 SPAGTLPEGCD-EAGRCLCQPEFAGPHCDRCRPGYHGF--PNCQACTCDPRGALDQLCGA 646
Query: 194 --VCRAAP 199
+CR P
Sbjct: 647 GGLCRCRP 654
Score = 31.6 bits (70), Expect = 0.74
Identities = 36/155 (23%), Positives = 59/155 (38%), Gaps = 31/155 (20%)
Query: 85 GFLGLVHCLPCKDSCD-----GVECGPGKACRMLGGRPRC---ECAPDCSGLPARLQV-C 135
G+ G +C C +CD CG G CR G EC+P G P+ + C
Sbjct: 622 GYHGFPNCQAC--TCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCVPCHC 679
Query: 136 GSDGATYRDECELRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVC 195
++G+ + C+ R+ +C P ++ + RC +CV G+ + C
Sbjct: 680 SAEGSLHA-ACDPRSGQCSCRPRVTGL---RC------------DTCV---PGAYNFPYC 720
Query: 196 RAAPC-PVPSSPGQELCGNNNVTYISSCHMRQATC 229
A C P +P V + H+ +C
Sbjct: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSC 755
>gi|123702038 keratin associated protein 5-9 [Homo sapiens]
Length = 169
Score = 39.7 bits (91), Expect = 0.003
Identities = 33/128 (25%), Positives = 42/128 (32%), Gaps = 11/128 (8%)
Query: 92 CLPCKDSCDGVECGPGKACRMLGGRPRCECAPDCSGLPARLQVCGSDGATYR-------D 144
C C C G CGP + +P C C P CS + CGS G +
Sbjct: 21 CGSCGSGCRG--CGPSCCAPVYCCKPVCCCVPACSCSSCGKRGCGSCGGSKGGCGSCGCS 78
Query: 145 ECE-LRAARCRGHPDLSVMYRGRCRKSCEHVVCPRPQSCVVDQTGSAHCVVCRAAPCPVP 203
+C + C S C+ C C +P C GS+ C PC
Sbjct: 79 QCSCCKPCCCSSGCGSSCCQCSCCKPYCSQCSCCKP-CCSSSGRGSSCCQSSCCKPCCSS 137
Query: 204 SSPGQELC 211
S G C
Sbjct: 138 SGCGSSCC 145
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.479
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,777,457
Number of Sequences: 37866
Number of extensions: 838894
Number of successful extensions: 2964
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 93
Number of HSP's successfully gapped in prelim test: 156
Number of HSP's that attempted gapping in prelim test: 2323
Number of HSP's gapped (non-prelim): 601
length of query: 263
length of database: 18,247,518
effective HSP length: 100
effective length of query: 163
effective length of database: 14,460,918
effective search space: 2357129634
effective search space used: 2357129634
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.