BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] (1251 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] 2522 0.0 gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] 1257 0.0 gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo s... 1240 0.0 gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] 1067 0.0 gi|117168245 ATPase, aminophospholipid transporter-like, Class I... 835 0.0 gi|157649069 ATPase, aminophospholipid transporter (APLT), class... 825 0.0 gi|17978471 ATPase, aminophospholipid transporter (APLT), class ... 823 0.0 gi|62632750 ATPase, class VI, type 11B [Homo sapiens] 622 e-178 gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] 616 e-176 gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] 613 e-175 gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] 595 e-169 gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] 595 e-169 gi|65301139 ATPase, class II, type 9A [Homo sapiens] 411 e-114 gi|41327760 ATPase, class II, type 9B [Homo sapiens] 402 e-111 gi|222352161 ATPase, class V, type 10D [Homo sapiens] 390 e-108 gi|149944474 ATPase, class V, type 10B [Homo sapiens] 387 e-107 gi|14424433 ATPase, class V, type 10A [Homo sapiens] 381 e-105 gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo s... 377 e-104 gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa... 88 6e-17 gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa... 88 6e-17 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 81 7e-15 gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap... 81 7e-15 gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 76 2e-13 gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 76 2e-13 gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 73 2e-12 gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa... 73 2e-12 gi|66932949 ATPase type 13A4 [Homo sapiens] 65 3e-10 gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 60 2e-08 gi|148839292 ATPase type 13A3 [Homo sapiens] 60 2e-08 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 55 3e-07 >gi|5031697 ATPase, class I, type 8B, member 1 [Homo sapiens] Length = 1251 Score = 2522 bits (6537), Expect = 0.0 Identities = 1251/1251 (100%), Positives = 1251/1251 (100%) Query: 1 MSTERDSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNREAEENREPFRK 60 MSTERDSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNREAEENREPFRK Sbjct: 1 MSTERDSETTFDEDSQPNDEVVPYSDDETEDELDDQGSAVEPEQNRVNREAEENREPFRK 60 Query: 61 ECTWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAA 120 ECTWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAA Sbjct: 61 ECTWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAA 120 Query: 121 NLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEV 180 NLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEV Sbjct: 121 NLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEV 180 Query: 181 IKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFK 240 IKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFK Sbjct: 181 IKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFK 240 Query: 241 MSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVI 300 MSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVI Sbjct: 241 MSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVI 300 Query: 301 RNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHA 360 RNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHA Sbjct: 301 RNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHA 360 Query: 361 YWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFIN 420 YWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFIN Sbjct: 361 YWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFIN 420 Query: 421 WDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHR 480 WDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHR Sbjct: 421 WDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHR 480 Query: 481 DASQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVD 540 DASQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVD Sbjct: 481 DASQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVD 540 Query: 541 RTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDR 600 RTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDR Sbjct: 541 RTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDR 600 Query: 601 KRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKE 660 KRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKE Sbjct: 601 KRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKE 660 Query: 661 IEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISK 720 IEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISK Sbjct: 661 IEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISK 720 Query: 721 LAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYA 780 LAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYA Sbjct: 721 LAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYA 780 Query: 781 KFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKR 840 KFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKR Sbjct: 781 KFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKR 840 Query: 841 RLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNM 900 RLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNM Sbjct: 841 RLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNM 900 Query: 901 IKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFA 960 IKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFA Sbjct: 901 IKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFA 960 Query: 961 FTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYI 1020 FTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYI Sbjct: 961 FTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYI 1020 Query: 1021 VGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASAL 1080 VGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASAL Sbjct: 1021 VGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASAL 1080 Query: 1081 VITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNAL 1140 VITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNAL Sbjct: 1081 VITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNAL 1140 Query: 1141 RQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQWQRRQQVFRR 1200 RQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQWQRRQQVFRR Sbjct: 1141 RQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQWQRRQQVFRR 1200 Query: 1201 GVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEYRRTGDS 1251 GVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEYRRTGDS Sbjct: 1201 GVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEYRRTGDS 1251 >gi|50083277 ATPase class I type 8B member 4 [Homo sapiens] Length = 1192 Score = 1257 bits (3253), Expect = 0.0 Identities = 647/1175 (55%), Positives = 844/1175 (71%), Gaps = 42/1175 (3%) Query: 66 VKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFL 125 VKANDR+Y+E KF +YA+N I T KYN TF+P+NLFEQF+R AN YFL Sbjct: 15 VKANDREYNE-------KF------QYADNRIHTSKYNILTFLPINLFEQFQRVANAYFL 61 Query: 126 ALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGR 185 LLILQ +P+IS+L W+TT+VPL++V+ +TA+KD DD RHK D ++NNR EV+ + + Sbjct: 62 CLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSK 121 Query: 186 FKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEI 245 + KW ++VGD+I+L+ N FV AD+LLLSSSEP+ LCYVETAELDGETNLK + +L + Sbjct: 122 LQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSV 181 Query: 246 TDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVIRNTDF 305 T + LA FDG + CE PNN+LDKF G L W+++ L+ +KI+LRGC++RNT + Sbjct: 182 TSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSW 241 Query: 306 CHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQ 365 C G+VIFAG DTK+M+NSGKT+FKRT ID LMN +V IF LI L LAIG++ WE+Q Sbjct: 242 CFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQ 301 Query: 366 VGNS-SWYLYDGEDDTPS-YRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDL 423 G+ +L+ E + S + GFL FW YII+LNT+VPISLYVSVEVIRLG S+FINWD Sbjct: 302 TGDQFRTFLFWNEGEKSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDR 361 Query: 424 QMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGD-HRDA 482 +MYY+ K PA ARTTTLNE+LGQI YIFSDKTGTLTQNIMTFK+C ING+IYG+ H D Sbjct: 362 KMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYGEVHDDL 421 Query: 483 SQHNH--NKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVD 540 Q + E VDFS + AD + F+DH+L+E I+ G +P+V +F LLA+CHTVM + Sbjct: 422 DQKTEITQEKEPVDFSVKSQADREFQFFDHHLMESIKMG-DPKVHEFLRLLALCHTVMSE 480 Query: 541 RTD-GQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSD 599 G+L YQ SPDEGALV AARNFGF F +RT TITI ELGT TY +LA LDFN+ Sbjct: 481 ENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNT 540 Query: 600 RKRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQE-TQDALDIFANETLRTLCLCY 658 RKRMS+IVR PEG IKLY KGADT+++E+LH N T D L FA E LRTL + Y Sbjct: 541 RKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAY 600 Query: 659 KEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETI 718 +++++K F EW+K A+ A+ RDE + +YEEIE+DL+LLGATA+EDKLQ+GV ET+ Sbjct: 601 RDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETV 660 Query: 719 SKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGV 778 + L+ A+IKIWVLTGDK+ETA NIG+AC +LT+D + N+ + R E ++ + + Sbjct: 661 TSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNL 720 Query: 779 YAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQS 838 + G NR ++ N ++ +K ++ ++ + + + Sbjct: 721 F--------------GQNR------NFSNGHVVCEKKQQLELDSIVEETITGDYALIING 760 Query: 839 KRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDV 898 A + + + ++LAC C VICCRVTP QKA VV+LVK+Y+ A+TLAIGDGANDV Sbjct: 761 HSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDV 820 Query: 899 NMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKN 958 +MIK+AHIGVGISGQEG+QAV++SDYSFAQFRYLQRLLLVHGRWSY RMCKFL YFFYKN Sbjct: 821 SMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKN 880 Query: 959 FAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGL 1018 FAFTLVHFW+ FF G+SAQT Y+ WFITL+N++YTSLPVL MG+ DQDVSD+ S+ P L Sbjct: 881 FAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQL 940 Query: 1019 YIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIAS 1078 Y GQ +LLFN ++FF+ +LHG+ TS++LFFIP GA+ G+DG+ +DYQSFAVT+A+ Sbjct: 941 YKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMAT 1000 Query: 1079 ALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASN 1138 +LVI V+ QI LDTSYWTF+N I+GSIA+YF I+F HS GI +FP+ F F G A + Sbjct: 1001 SLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARH 1060 Query: 1139 ALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQWQRRQQVF 1198 +L Q IWL I+LT ++PVVA RFL + ++P+ SD+I++ +K K R+ Sbjct: 1061 SLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIRRWQKAQKKARPPSSRRPRT 1120 Query: 1199 RRGVSTRRSAYAFSHQRGYADLISSGRSIRKKRSP 1233 RR S+RRS YAF+HQ GY +LI+SG+++R K P Sbjct: 1121 RRS-SSRRSGYAFAHQEGYGELITSGKNMRAKNPP 1154 >gi|40316837 ATPase, class I, type 8B, member 2 isoform a [Homo sapiens] Length = 1223 Score = 1240 bits (3209), Expect = 0.0 Identities = 637/1191 (53%), Positives = 841/1191 (70%), Gaps = 50/1191 (4%) Query: 65 QVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYF 124 + +ANDR+Y+E KF +YA+N IKT KYN TF+P+NLFEQF+ AN YF Sbjct: 48 RARANDREYNE-------KF------QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYF 94 Query: 125 LALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDG 184 L LLILQ +PQIS+L+W+TT+VPL++VL +TA+KD DD RHK D ++NNR +V+ +G Sbjct: 95 LFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLING 154 Query: 185 RFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLE 244 + +W + VGD+I+L+ N FV AD+LLLSSSEP+ LCY+ETAELDGETN+K + ++ Sbjct: 155 ILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIP 214 Query: 245 ITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVIRNTD 304 +T + L LA FDG + CE PNN+LDKF+GTL+W+ FPL +LLRGCV+RNT+ Sbjct: 215 VTSE-LGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 273 Query: 305 FCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEA 364 +C GLVIFAG DTK+M+NSG+T+FKRT ID LMN +V IF L+ + LAIG+A WE Sbjct: 274 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 333 Query: 365 QVG-NSSWYL-YDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWD 422 +VG YL +D D+ + GFL FW YII+LNT+VPISLYVSVEVIRLG S+FINWD Sbjct: 334 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWD 393 Query: 423 LQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDA 482 +M+ +K TPA+ARTTTLNE+LGQ+ YIFSDKTGTLTQNIM F KC ING YGD D Sbjct: 394 KKMFCMKKRTPAEARTTTLNEELGQVEYIFSDKTGTLTQNIMVFNKCSINGHSYGDVFDV 453 Query: 483 SQHN---HNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVM- 538 H + E VDFS+N AD K F+D L+E ++ G +P +FF LL++CHTVM Sbjct: 454 LGHKAELGERPEPVDFSFNPLADKKFLFWDPSLLEAVKIG-DPHTHEFFRLLSLCHTVMS 512 Query: 539 VDRTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFNS 598 ++ +G+L Y+A SPDEGALV AARNFGF F +RT TIT+ E+GT TY +LAILDFN+ Sbjct: 513 EEKNEGELYYKAQSPDEGALVTAARNFGFVFRSRTPKTITVHEMGTAITYQLLAILDFNN 572 Query: 599 DRKRMSIIVRTPEGNIKLYCKGADTVIYERLHR-MNPTKQETQDALDIFANETLRTLCLC 657 RKRMS+IVR PEG I+LYCKGADT++ +RLH T D L+ +A E LRTL L Sbjct: 573 IRKRMSVIVRNPEGKIRLYCKGADTILLDRLHHSTQELLNTTMDHLNEYAGEGLRTLVLA 632 Query: 658 YKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPET 717 YK+++E+ + EW ++ + AS+A +R++ L +YEE+E +++LLGATAIEDKLQ GVPET Sbjct: 633 YKDLDEEYYEEWAERRLQASLAQDSREDRLASIYEEVENNMMLLGATAIEDKLQQGVPET 692 Query: 718 ISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGG 777 I+ L A+IKIWVLTGDK+ETA NIG++C++LT+D T + +++L R E ++ R Sbjct: 693 IALLTLANIKIWVLTGDKQETAVNIGYSCKMLTDDMTEVFIVTGHTVLEVREELRKAR-- 750 Query: 778 VYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQ 837 + + + S N + K +K+ + E + Sbjct: 751 ------------------EKMMDSSRSVGNGFTYQDKLSSSKLTSV-LEAVAGEYALVIN 791 Query: 838 SKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGAND 897 A + + F++ AC C AVICCRVTP QKA VV+LVK+YKKA+TLAIGDGAND Sbjct: 792 GHSLAHALEADMELEFLETACACKAVICCRVTPLQKAQVVELVKKYKKAVTLAIGDGAND 851 Query: 898 VNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYK 957 V+MIKTAHIGVGISGQEG+QAV++SDYSF+QF++LQRLLLVHGRWSY+RMCKFL YFFYK Sbjct: 852 VSMIKTAHIGVGISGQEGIQAVLASDYSFSQFKFLQRLLLVHGRWSYLRMCKFLCYFFYK 911 Query: 958 NFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPG 1017 NFAFT+VHFW+ FF G+SAQT Y+ +FITLYN++YTSLPVL MG+ DQDV ++ S+ +P Sbjct: 912 NFAFTMVHFWFGFFCGFSAQTVYDQYFITLYNIVYTSLPVLAMGVFDQDVPEQRSMEYPK 971 Query: 1018 LYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIA 1077 LY GQ +LLFN + FF+ + G+ TS+++FFIP G + DG +DYQSFAVT+A Sbjct: 972 LYEPGQLNLLFNKREFFICIAQGIYTSVLMFFIPYGVFADATRDDGTQLADYQSFAVTVA 1031 Query: 1078 SALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTAS 1137 ++LVI V+ QIGLDT YWT +N F I+GS+A+YF I+F HS G+ +FP+ F+F G A Sbjct: 1032 TSLVIVVSVQIGLDTGYWTAINHFFIWGSLAVYFAILFAMHSNGLFDMFPNQFRFVGNAQ 1091 Query: 1138 NALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKI---QKHRKRLKAEEQWQRR 1194 N L QP +WLTI+LT VC++PVVA RFL + + P SD + Q RK+ KA+ + RR Sbjct: 1092 NTLAQPTVWLTIVLTTVVCIMPVVAFRFLRLNLKPDLSDTVRYTQLVRKKQKAQHRCMRR 1151 Query: 1195 QQVFRRGVSTRRSAYAFSHQRGYADLISSGRSIRKKRSPLDAIVADGTAEY 1245 V R G +RRS YAFSHQ G+ +LI SG+++R L + ++ + Sbjct: 1152 --VGRTG--SRRSGYAFSHQEGFGELIMSGKNMRLSSLALSSFTTRSSSSW 1198 >gi|44888835 ATPase, class I, type 8B, member 3 [Homo sapiens] Length = 1300 Score = 1067 bits (2760), Expect = 0.0 Identities = 563/1209 (46%), Positives = 793/1209 (65%), Gaps = 84/1209 (6%) Query: 63 TWQVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANL 122 TW+V+AN+R Y+ Q F LC + KY N I+T KYN ++F+P+NL+EQF R +NL Sbjct: 106 TWKVQANNRAYNGQ--FKEKVILCWQRKKYKTNVIRTAKYNFYSFLPLNLYEQFHRVSNL 163 Query: 123 YFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIK 182 +FL ++ILQ++P ISTL W++ P++ +L + A +DLVDD+ RHK D+ INNR C+++ Sbjct: 164 FFLIIIILQSIPDISTLPWFSLSTPMVCLLFIRATRDLVDDMGRHKSDRAINNRPCQILM 223 Query: 183 DGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMS 242 FK KW+++ VGDV+ L+K++ VPAD+LLL+S+EP+SLCYVET ++DGETNLKF+ + Sbjct: 224 GKSFKQKKWQDLCVGDVVCLRKDNIVPADMLLLASTEPSSLCYVETVDIDGETNLKFRQA 283 Query: 243 LEITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVIRN 302 L +T + L +A+F G + CE PN+R+ F G L W + + LD +LLRGC IRN Sbjct: 284 LMVTHKELATIKKMASFQGTVTCEAPNSRMHHFVGCLEWNDKKYSLDIGNLLLRGCRIRN 343 Query: 303 TDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYW 362 TD C+GLVI+AG DTKIMKN GK KRTK+D LMN +V IF+ ++L+ LA G + Sbjct: 344 TDTCYGLVIYAGFDTKIMKNCGKIHLKRTKLDLLMNKLVVVIFISVVLVCLVLAFGFGFS 403 Query: 363 EAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWD 422 + + +YL + + F +FW ++I+L+ +P+S+++ E I LG S FI+WD Sbjct: 404 VKEFKDHHYYLSGVHGSSVAAESFFVFWSFLILLSVTIPMSMFILSEFIYLGNSVFIDWD 463 Query: 423 LQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDA 482 +QMYY +D PAKAR+T+LN+ LGQ+ YIFSDKTGTLTQNI+TF KCCI+G++YG +A Sbjct: 464 VQMYYKPQDVPAKARSTSLNDHLGQVEYIFSDKTGTLTQNILTFNKCCISGRVYGPDSEA 523 Query: 483 SQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMV--- 539 + + ++ + WN +ADGKL F++ L+ +++ + VR+F+ LLA+CHTVMV Sbjct: 524 T----TRPKENPYLWNKFADGKLLFHNAALLHLVRTNGDEAVREFWRLLAICHTVMVRES 579 Query: 540 --DRTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFN 597 +R D QL YQAASPDEGALV AARNFG+ FL+RTQ+T+TI ELG ER Y VLAI+DFN Sbjct: 580 PRERPD-QLLYQAASPDEGALVTAARNFGYVFLSRTQDTVTIMELGEERVYQVLAIMDFN 638 Query: 598 SDRKRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLC 657 S RKRMS++VR PEG I LY KGADTVI+ERLHR + T++AL FA ETLRTLCL Sbjct: 639 STRKRMSVLVRKPEGAICLYTKGADTVIFERLHRRGAMEFATEEALAAFAQETLRTLCLA 698 Query: 658 YKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPET 717 Y+E+ E + +W ++ AS+ NR +AL + LLGATAIED+LQDGVPET Sbjct: 699 YREVAEDIYEDWQQRHQEASLLLQNRAQALQQ----------LLGATAIEDRLQDGVPET 748 Query: 718 ISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGG 777 I L K++IKIWVLTGDK+ETA NIGFACELL+E+ I ++I+ +L EN N Sbjct: 749 IKCLKKSNIKIWVLTGDKQETAVNIGFACELLSENMLILEEKEISRILETYWENSNNL-- 806 Query: 778 VYAKFAPPVQESFFPPGGNRALIITGSWLNEILLE-KKTKRNKILKLKFPRTEEE----- 831 +ES AL+I G +L+++L+ +K R + +E Sbjct: 807 -------LTRESLSQV--KLALVINGDFLDKLLVSLRKEPRALAQNVNMDEAWQELGQSR 857 Query: 832 ------RRMR--------------TQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPK 871 RR+ Q R + + +++ FVDLA +C AVICCRVTPK Sbjct: 858 RDFLYARRLSLLCRRFGLPLAAPPAQDSRARRSSEVLQERAFVDLASKCQAVICCRVTPK 917 Query: 872 QKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRY 931 QKA++V LVK+Y + +TLAIGDGAND+NMIKTA +GVG++GQEGMQAV +SD+ QF + Sbjct: 918 QKALIVALVKKYHQVVTLAIGDGANDINMIKTADVGVGLAGQEGMQAVQNSDFVLGQFCF 977 Query: 932 LQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVL 991 LQRLLLVHGRWSY+R+CKFLRYFFYK+ A +V W++ +NG++ Q YE WF+ L+N+L Sbjct: 978 LQRLLLVHGRWSYVRICKFLRYFFYKSMASMMVQVWFACYNGFTGQPLYEGWFLALFNLL 1037 Query: 992 YTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIP 1051 Y++LPVL +GL +QDVS + SL P LY+VGQ+D LFNY F ++ HGV TS++ FF+ Sbjct: 1038 YSTLPVLYIGLFEQDVSAEQSLEKPELYVVGQKDELFNYWVFVQAIAHGVTTSLVNFFMT 1097 Query: 1052 LGAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYF 1111 L T G + SD+QSFAV +A + ++++ ++ L YWT + +I S+ Y Sbjct: 1098 LWISRDTAGP--ASFSDHQSFAVVVALSCLLSITMEVILIIKYWTALCVATILLSLGFYA 1155 Query: 1112 GIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIW 1171 + S + + P+ F F + + P I L ++L+V++ PV+A+R I+ Sbjct: 1156 IMTTTTQSFWLFRVSPTTFPFLYADLSVMSSPSILLVVLLSVSINTFPVLALR----VIF 1211 Query: 1172 PSESDKIQKHRKRLKAEEQWQRR---QQVF--------RRGVSTRRSAYAFSHQRGYADL 1220 P+ K L+A+E+ +++F R RRS+YAFSH+ GYA+L Sbjct: 1212 PA--------LKELRAKEEKVEEGPSEEIFTMEPLPHVHRESRARRSSYAFSHREGYANL 1263 Query: 1221 ISSGRSIRK 1229 I+ G +R+ Sbjct: 1264 ITQGTILRR 1272 >gi|117168245 ATPase, aminophospholipid transporter-like, Class I, type 8A, member 2 [Homo sapiens] Length = 1188 Score = 835 bits (2156), Expect = 0.0 Identities = 468/1151 (40%), Positives = 685/1151 (59%), Gaps = 75/1151 (6%) Query: 38 SAVEPEQNRVNREAEENREPFRKECTWQVKANDRK-YHEQPHFMNTKFLCIKESKYANNA 96 S+V P ++ + + E+ Q++A R Y QPH +K+ +N Sbjct: 23 SSVGPVRSSLGYKKAEDEMSRATSVGDQLEAPARTIYLNQPHL----------NKFRDNQ 72 Query: 97 IKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTA 156 I T KY+ TF+P L+EQ +RAAN +FL + +LQ +P +S YTTLVPL+++L + Sbjct: 73 ISTAKYSVLTFLPRFLYEQIRRAANAFFLFIALLQQIPDVSPTGRYTTLVPLIIILTIAG 132 Query: 157 IKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLS 216 IK++V+D RHK D +N + V+++G + WKE+ VGD++++ ++PAD++LLS Sbjct: 133 IKEIVEDFKRHKADNAVNKKKTIVLRNGMWHTIMWKEVAVGDIVKVVNGQYLPADVVLLS 192 Query: 217 SSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFT 276 SSEP ++CYVETA LDGETNLK + L T +Q + L G IECE PN L FT Sbjct: 193 SSEPQAMCYVETANLDGETNLKIRQGLSHTAD-MQTREVLMKLSGTIECEGPNRHLYDFT 251 Query: 277 GTLFWRNTSF-PLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRFKRTKIDY 335 G L S L D+ILLRG +RNT + G+V++ G DTK+M+NS K KR+ ++ Sbjct: 252 GNLNLDGKSLVALGPDQILLRGTQLRNTQWVFGIVVYTGHDTKLMQNSTKAPLKRSNVEK 311 Query: 336 LMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIV 395 + N + +F +L++++ + G YW G +WY+ + + ++ L+ +II+ Sbjct: 312 VTNVQILVLFGILLVMALVSSAGALYWNRSHGEKNWYIKKMDTTSDNFGYNLLT--FIIL 369 Query: 396 LNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDK 455 N ++PISL V++EV++ Q+ FINWD MYY DTPA ART+ LNE+LGQ+ Y+FSDK Sbjct: 370 YNNLIPISLLVTLEVVKYTQALFINWDTDMYYIGNDTPAMARTSNLNEELGQVKYLFSDK 429 Query: 456 TGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFS-WNTYADGKLAFYDHYLIE 514 TGTLT NIM FKKC I G YG + ++ + DF F D L++ Sbjct: 430 TGTLTCNIMNFKKCSIAGVTYGHFPELAREPSSD----DFCRMPPPCSDSCDFDDPRLLK 485 Query: 515 QIQSGKE--PEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAARNFGFAFLAR 572 I+ P +++F LLAVCHTV+ ++ + YQA+SPDE ALV A+ GF F AR Sbjct: 486 NIEDRHPTAPCIQEFLTLLAVCHTVVPEKDGDNIIYQASSPDEAALVKGAKKLGFVFTAR 545 Query: 573 TQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGADTVIYERLHRM 632 T ++ I +G E+T+ +L +L+F+SDRKRMS+IVRTP G ++LYCKGAD VI+ERL + Sbjct: 546 TPFSVIIEAMGQEQTFGILNVLEFSSDRKRMSVIVRTPSGRLRLYCKGADNVIFERLSKD 605 Query: 633 NPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYE 692 + +ET L+ FA E LRTLC+ Y ++ E E+ EW K + AS +R + L++ YE Sbjct: 606 SKYMEETLCHLEYFATEGLRTLCVAYADLSENEYEEWLKVYQEASTILKDRAQRLEECYE 665 Query: 693 EIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTED 752 IEK+L+LLGATAIED+LQ GVPETI+ L KA+IKIWVLTGDK+ETA NIG++C L++++ Sbjct: 666 IIEKNLLLLGATAIEDRLQAGVPETIATLLKAEIKIWVLTGDKQETAINIGYSCRLVSQN 725 Query: 753 TTICY--GEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWLNEIL 810 + + +++ A ++ + G + K + ALII G Sbjct: 726 MALILLKEDSLDATRAAITQHCTDLGNLLGK------------ENDVALIIDGH------ 767 Query: 811 LEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTP 870 LK+ + E RR +F+DLA C AVICCRV+P Sbjct: 768 -----------TLKYALSFEVRR------------------SFLDLALSCKAVICCRVSP 798 Query: 871 KQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFR 930 QK+ +VD+VK+ KAITLAIGDGANDV MI+TAH+GVGISG EGMQA +SDY+ AQF Sbjct: 799 LQKSEIVDVVKKRVKAITLAIGDGANDVGMIQTAHVGVGISGNEGMQATNNSDYAIAQFS 858 Query: 931 YLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNV 990 YL++LLLVHG WSY R+ K + Y FYKN ++ W++F NG+S Q +E W I LYNV Sbjct: 859 YLEKLLLVHGAWSYNRVTKCILYCFYKNVVLYIIELWFAFVNGFSGQILFERWCIGLYNV 918 Query: 991 LYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFI 1050 ++T+LP +G+ ++ + + LRFP LY + Q FN K F+ ++ ++ S+ILF+ Sbjct: 919 IFTALPPFTLGIFERSCTQESMLRFPQLYKITQNGEGFNTKVFWGHCINALVHSLILFWF 978 Query: 1051 PLGAY-LQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIAL 1109 P+ A TV G A +DY + + +V+TV + GL+T+ WT + +++GS+ Sbjct: 979 PMKALEHDTVLTSGHA-TDYLFVGNIVYTYVVVTVCLKAGLETTAWTKFSHLAVWGSMLT 1037 Query: 1110 YFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMT 1169 + + F +S I P A G A+ L + WL + L CL+ VA R T Sbjct: 1038 WL-VFFGIYST-IWPTIPIAPDMRGQATMVLSSAHFWLGLFLVPTACLIEDVAWRAAKHT 1095 Query: 1170 IWPSESDKIQK 1180 + +++Q+ Sbjct: 1096 CKKTLLEEVQE 1106 >gi|157649069 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 isoform b [Homo sapiens] Length = 1149 Score = 825 bits (2131), Expect = 0.0 Identities = 454/1094 (41%), Positives = 648/1094 (59%), Gaps = 72/1094 (6%) Query: 90 SKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLL 149 +K+ NN + T KYN TF+P L+ QF+RAAN +FL + +LQ +P +S YTTLVPLL Sbjct: 47 TKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLL 106 Query: 150 VVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVP 209 +L V AIK++++D+ RHK D +N + +V+++G +++ W+++ VGD++ +K +++P Sbjct: 107 FILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVNVGDIVIIKGKEYIP 166 Query: 210 ADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPN 269 AD +LLSSSEP ++CY+ET+ LDGETNLK + L T ++ D+L G IECE PN Sbjct: 167 ADTVLLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSD-IKDVDSLMRISGRIECESPN 225 Query: 270 NRLDKFTGTL-FWRNTSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRF 328 L F G + + + PL AD+ILLRG +RNT + HG+V++ G DTK+M+NS Sbjct: 226 RHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPL 285 Query: 329 KRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYRGFLI 388 K + ++ + N + +F +LI +S ++G A W + WYL ++ L Sbjct: 286 KLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFG--LN 343 Query: 389 FWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQI 448 F +II+ N ++PISL V++EV++ Q++FINWDL M+Y DT A ART+ LNE+LGQ+ Sbjct: 344 FLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQV 403 Query: 449 HYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYADGKLAFY 508 YIFSDKTGTLT N+M FKKC I G YG + + + D K F Sbjct: 404 KYIFSDKTGTLTCNVMQFKKCTIAGVAYGQN------------------SQFGDEK-TFS 444 Query: 509 DHYLIEQIQSGKE--PEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAARNFG 566 D L+E +Q+ P + +F ++AVCHT + +R ++ YQAASPDEGALV AA+ Sbjct: 445 DSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQLN 504 Query: 567 FAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGADTVIY 626 F F RT +++ I LG E Y +L +L+F S RKRMS+IVRTP G ++LYCKGADTVIY Sbjct: 505 FVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVIY 564 Query: 627 ERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEA 686 +RL + K+ T L+ FA E LRTLC EI E +F EW + AS + NR Sbjct: 565 DRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLLK 624 Query: 687 LDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFAC 746 L++ YE IEK+L LLGATAIEDKLQD VPETI L KADIKIW+LTGDK Sbjct: 625 LEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDK----------- 673 Query: 747 ELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWL 806 ++T I G L ++N G + + E G R Sbjct: 674 ----QETAINIGHSCKLL-------KKNMGMIV------INEGSLD--GTR--------- 705 Query: 807 NEILLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICC 866 E L T L R E + + K A ++ F+DLA C AVICC Sbjct: 706 -ETLSRHCTTLGDAL-----RKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVICC 759 Query: 867 RVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSF 926 RV+P QK+ VV++VK+ K +TLAIGDGANDV+MI+TAH+GVGISG EG+QA SSDYS Sbjct: 760 RVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYSI 819 Query: 927 AQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFIT 986 AQF+YL+ LL++HG W+Y R+ K + Y FYKN ++ W++F NG+S Q +E W I Sbjct: 820 AQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCIG 879 Query: 987 LYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMI 1046 LYNV++T++P L +G+ ++ + L++P LY Q L FN K F+V L+G+ S+I Sbjct: 880 LYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSVI 939 Query: 1047 LFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGS 1106 LF+ PL A SDY + + +VITV + GL+TSYWT+ + +I+GS Sbjct: 940 LFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWGS 999 Query: 1107 IALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFL 1166 IAL+ + F +S+ + P A +G A+ W+ ++ LL V + + Sbjct: 1000 IALWV-VFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKVI 1057 Query: 1167 SMTIWPSESDKIQK 1180 T + + D++Q+ Sbjct: 1058 KRTAFKTLVDEVQE 1071 >gi|17978471 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 isoform a [Homo sapiens] Length = 1164 Score = 823 bits (2126), Expect = 0.0 Identities = 452/1095 (41%), Positives = 650/1095 (59%), Gaps = 59/1095 (5%) Query: 90 SKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLL 149 +K+ NN + T KYN TF+P L+ QF+RAAN +FL + +LQ +P +S YTTLVPLL Sbjct: 47 TKFCNNHVSTAKYNIITFLPRFLYSQFRRAANSFFLFIALLQQIPDVSPTGRYTTLVPLL 106 Query: 150 VVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVP 209 +L V AIK++++D+ RHK D +N + +V+++G +++ W+++ VG+++++ + +P Sbjct: 107 FILAVAAIKEIIEDIKRHKADNAVNKKQTQVLRNGAWEIVHWEKVAVGEIVKVTNGEHLP 166 Query: 210 ADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPN 269 AD++ LSSSEP ++CY+ET+ LDGETNLK + L T ++ D+L G IECE PN Sbjct: 167 ADLISLSSSEPQAMCYIETSNLDGETNLKIRQGLPATSD-IKDVDSLMRISGRIECESPN 225 Query: 270 NRLDKFTGTL-FWRNTSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRF 328 L F G + + + PL AD+ILLRG +RNT + HG+V++ G DTK+M+NS Sbjct: 226 RHLYDFVGNIRLDGHGTVPLGADQILLRGAQLRNTQWVHGIVVYTGHDTKLMQNSTSPPL 285 Query: 329 KRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYRGFLI 388 K + ++ + N + +F +LI +S ++G A W + WYL ++ L Sbjct: 286 KLSNVERITNVQILILFCILIAMSLVCSVGSAIWNRRHSGKDWYLNLNYGGASNFG--LN 343 Query: 389 FWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQI 448 F +II+ N ++PISL V++EV++ Q++FINWDL M+Y DT A ART+ LNE+LGQ+ Sbjct: 344 FLTFIILFNNLIPISLLVTLEVVKFTQAYFINWDLDMHYEPTDTAAMARTSNLNEELGQV 403 Query: 449 HYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSW-NTYADGKLAF 507 YIFSDKTGTLT N+M FKKC I G YG + + + E W N+ + F Sbjct: 404 KYIFSDKTGTLTCNVMQFKKCTIAGVAYGHVPEPEDYGCSPDE-----WQNSQFGDEKTF 458 Query: 508 YDHYLIEQIQSGKE--PEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAARNF 565 D L+E +Q+ P + +F ++AVCHT + +R ++ YQAASPDEGALV AA+ Sbjct: 459 SDSSLLENLQNNHPTAPIICEFLTMMAVCHTAVPEREGDKIIYQAASPDEGALVRAAKQL 518 Query: 566 GFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGADTVI 625 F F RT +++ I LG E Y +L +L+F S RKRMS+IVRTP G ++LYCKGADTVI Sbjct: 519 NFVFTGRTPDSVIIDSLGQEERYELLNVLEFTSARKRMSVIVRTPSGKLRLYCKGADTVI 578 Query: 626 YERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDE 685 Y+RL + K+ T L+ FA E LRTLC EI E +F EW + AS + NR Sbjct: 579 YDRLAETSKYKEITLKHLEQFATEGLRTLCFAVAEISESDFQEWRAVYQRASTSVQNRLL 638 Query: 686 ALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFA 745 L++ YE IEK+L LLGATAIEDKLQD VPETI L KADIKIW+LTGDK Sbjct: 639 KLEESYELIEKNLQLLGATAIEDKLQDQVPETIETLMKADIKIWILTGDK---------- 688 Query: 746 CELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSW 805 ++T I G L ++N G + + E G R Sbjct: 689 -----QETAINIGHSCKLL-------KKNMGMIV------INEGSLD--GTR-------- 720 Query: 806 LNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVIC 865 E L T L R E + + K A ++ F+DLA C AVIC Sbjct: 721 --ETLSRHCTTLGDAL-----RKENDFALIIDGKTLKYALTFGVRQYFLDLALSCKAVIC 773 Query: 866 CRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYS 925 CRV+P QK+ VV++VK+ K +TLAIGDGANDV+MI+TAH+GVGISG EG+QA SSDYS Sbjct: 774 CRVSPLQKSEVVEMVKKQVKVVTLAIGDGANDVSMIQTAHVGVGISGNEGLQAANSSDYS 833 Query: 926 FAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFI 985 AQF+YL+ LL++HG W+Y R+ K + Y FYKN ++ W++F NG+S Q +E W I Sbjct: 834 IAQFKYLKNLLMIHGAWNYNRVSKCILYCFYKNIVLYIIEIWFAFVNGFSGQILFERWCI 893 Query: 986 TLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSM 1045 LYNV++T++P L +G+ ++ + L++P LY Q L FN K F+V L+G+ S+ Sbjct: 894 GLYNVMFTAMPPLTLGIFERSCRKENMLKYPELYKTSQNALDFNTKVFWVHCLNGLFHSV 953 Query: 1046 ILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFG 1105 ILF+ PL A SDY + + +VITV + GL+TSYWT+ + +I+G Sbjct: 954 ILFWFPLKALQYGTAFGNGKTSDYLLLGNFVYTFVVITVCLKAGLETSYWTWFSHIAIWG 1013 Query: 1106 SIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRF 1165 SIAL+ + F +S+ + P A +G A+ W+ ++ LL V + Sbjct: 1014 SIALWV-VFFGIYSS-LWPAIPMAPDMSGEAAMLFSSGVFWMGLLFIPVASLLLDVVYKV 1071 Query: 1166 LSMTIWPSESDKIQK 1180 + T + + D++Q+ Sbjct: 1072 IKRTAFKTLVDEVQE 1086 >gi|62632750 ATPase, class VI, type 11B [Homo sapiens] Length = 1177 Score = 622 bits (1604), Expect = e-178 Identities = 397/1128 (35%), Positives = 593/1128 (52%), Gaps = 98/1128 (8%) Query: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150 K+ +N I + KY + F+P NLFEQF+R AN YFL + ++Q + T T+ +PL Sbjct: 38 KFIDNRIISSKYTVWNFVPKNLFEQFRRVANFYFLIIFLVQLMIDTPTSP-VTSGLPLFF 96 Query: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPA 210 V+ VTAIK +D RH D E+N V++ G + K I+VGD++R+ K++ PA Sbjct: 97 VITVTAIKQGYEDWLRHNSDNEVNGAPVYVVRSGGLVKTRSKNIRVGDIVRIAKDEIFPA 156 Query: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270 D++LLSS + C+V TA LDGETNLK +++ T LQ L T IEC++P Sbjct: 157 DLVLLSSDRLDGSCHVTTASLDGETNLKTHVAVPET-ALLQTVANLDTLVAVIECQQPEA 215 Query: 271 RLDKFTGTLF----WRNTSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKT 326 L +F G + PL + +LLRG ++NT G+ ++ G +TK+ N Sbjct: 216 DLYRFMGRMIITQQMEEIVRPLGPESLLLRGARLKNTKEIFGVAVYTGMETKMALNYKSK 275 Query: 327 RFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVG-NSSWYLYDGEDDTPS--- 382 KR+ ++ MN + V+LI + I W+A+ + WY E S Sbjct: 276 SQKRSAVEKSMNTFLIIYLVILISEAVISTILKYTWQAEEKWDEPWYNQKTEHQRNSSKI 335 Query: 383 YRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLN 442 R F ++++ N ++PISLYV+VE+ + S FI WDL +Y+ E D A+ T+ LN Sbjct: 336 LRFISDFLAFLVLYNFIIPISLYVTVEMQKFLGSFFIGWDLDLYHEESDQKAQVNTSDLN 395 Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIY----------GDHRDASQHNHNKIEQ 492 E+LGQ+ Y+F+DKTGTLT+N M F++C ING Y G D+S+ N + + Sbjct: 396 EELGQVEYVFTDKTGTLTENEMQFRECSINGMKYQEINGRLVPEGPTPDSSEGNLSYLSS 455 Query: 493 VDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRT------DG-- 544 + N + + + + KE ++ FF +++CHTV + DG Sbjct: 456 LSHLNNLSHLTTSSSFRTSPENETELIKEHDL--FFKAVSLCHTVQISNVQTDCTGDGPW 513 Query: 545 -------QLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTERTYNVLAILDFN 597 QL Y A+SPDE ALV AA G F+ ++ T+ + LG Y +L IL+F+ Sbjct: 514 QSNLAPSQLEYYASSPDEKALVEAAARIGIVFIGNSEETMEVKTLGKLERYKLLHILEFD 573 Query: 598 SDRKRMSIIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLC 657 SDR+RMS+IV+ P G L+ KGA++ I + + ++T+ +D FA + LRTLC+ Sbjct: 574 SDRRRMSVIVQAPSGEKLLFAKGAESSILPKC--IGGEIEKTRIHVDEFALKGLRTLCIA 631 Query: 658 YKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPET 717 Y++ KE+ E +K+ A A R+E L V++ IEKDLILLGATA+ED+LQD V ET Sbjct: 632 YRKFTSKEYEEIDKRIFEARTALQQREEKLAAVFQFIEKDLILLGATAVEDRLQDKVRET 691 Query: 718 ISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGG 777 I L A IK+WVLTGDK ETA ++ +C I E IN + Q Sbjct: 692 IEALRMAGIKVWVLTGDKHETAVSVSLSCGHFHRTMNIL--ELINQKSDSECAEQ----- 744 Query: 778 VYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQ 837 + A + E G L++ G+ L+ L E Sbjct: 745 -LRQLARRITEDHVIQHG---LVVDGTSLSLALRE------------------------- 775 Query: 838 SKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVK-RYKKAITLAIGDGAN 896 +K F+++ CSAV+CCR+ P QKA V+ L+K +K ITLA+GDGAN Sbjct: 776 -----------HEKLFMEVCRNCSAVLCCRMAPLQKAKVIRLIKISPEKPITLAVGDGAN 824 Query: 897 DVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFY 956 DV+MI+ AH+G+GI G+EG QA +SDY+ A+F++L +LL VHG + YIR+ ++YFFY Sbjct: 825 DVSMIQEAHVGIGIMGKEGRQAARNSDYAIARFKFLSKLLFVHGHFYYIRIATLVQYFFY 884 Query: 957 KNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFP 1016 KN F F Y F+ +S QT Y+ ++TLYN+ +TSLP+L+ LL+Q V + P Sbjct: 885 KNVCFITPQFLYQFYCLFSQQTLYDSVYLTLYNICFTSLPILIYSLLEQHVDPHVLQNKP 944 Query: 1017 GLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQ-----S 1071 LY ++ L + K F + G + I FF G+YL +G+D + Q + Sbjct: 945 TLYRDISKNRLLSIKTFLYWTILGFSHAFIFFF---GSYL-LIGKDTSLLGNGQMFGNWT 1000 Query: 1072 FAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQ 1131 F + + +VITV ++ L+T +WT++N +GSI YF +F GI F + Sbjct: 1001 FGTLVFTVMVITVTVKMALETHFWTWINHLVTWGSIIFYF--VFSLFYGGILWPFLGSQN 1058 Query: 1132 FTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQ 1179 L W IIL V CL + + + P+ ++K Q Sbjct: 1059 MYFVFIQLLSSGSAWFAIILMVVTCLFLDIIKKVFDRHLHPTSTEKAQ 1106 >gi|150421684 ATPase, class VI, type 11A isoform a [Homo sapiens] Length = 1134 Score = 616 bits (1588), Expect = e-176 Identities = 391/1140 (34%), Positives = 610/1140 (53%), Gaps = 105/1140 (9%) Query: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150 +Y +N I + KY + FIP NLFEQF+R AN YFL + ++Q + T T+ +PL Sbjct: 44 RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSP-VTSGLPLFF 102 Query: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPA 210 V+ VTAIK +D RHK D +N I+ G+ + ++++VGD++ +K+++ P Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162 Query: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270 D++ LSS+ + C+V TA LDGE++ K +++ T + ED + IECE+P Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEED-IGGLHATIECEQPQP 221 Query: 271 RLDKFTGTLFWRN-----TSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGK 325 L KF G + + PL ++ +LLRG ++NT+ G+ I+ G +TK+ N Sbjct: 222 DLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQS 281 Query: 326 TRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQ-VGNSSWYLYDGEDDTPS-- 382 KR+ ++ MN + +LI + + W+++ + WY E + Sbjct: 282 KSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNL 341 Query: 383 -YRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441 + F F ++++ N ++P+S+YV+VE+ + S+FI WD M+ E T+ L Sbjct: 342 FLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDL 401 Query: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQH---NHNKIEQVDFSWN 498 NE+LGQ+ YIF+DKTGTLT+N M FK+CCI G +Y H + + I+ +D S + Sbjct: 402 NEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPS 461 Query: 499 TYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMV---DRTDGQLN-------- 547 +G+E E FF L +CHTV V D DG Sbjct: 462 V------------------NGRERE-ELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSC 502 Query: 548 -YQAASPDEGALVNAARNFGFAFLARTQNTITI--SELGTERTYNVLAILDFNSDRKRMS 604 Y ++SPDE ALV + GF +L N + I E ER + +L IL F+S R+RMS Sbjct: 503 VYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIER-FELLEILSFDSVRRRMS 561 Query: 605 IIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEK 664 +IV++ G I L+CKGAD+ I+ R+ + + + ++ A E LRTLC+ YK + ++ Sbjct: 562 VIVKSATGEIYLFCKGADSSIFPRV--IEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE 619 Query: 665 EFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKA 724 E+ K AA VA +R++ L + YE+IEKDL LLGATA+ED+LQ+ +TI L KA Sbjct: 620 EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKA 679 Query: 725 DIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFAP 784 IK+WVLTGDK ETA +AC+L +T + L R+E Q ++ Sbjct: 680 GIKVWVLTGDKMETAAATCYACKLFRRNTQLL------ELTTKRIEEQSLHDVLFELSKT 733 Query: 785 PVQESFFPPGGNRA----------LIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRM 834 ++ S N + LII G+ L+ I+ Sbjct: 734 VLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIM------------------------ 769 Query: 835 RTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKK-AITLAIGD 893 K R + ++ F+++ CSAV+CCR+ P QKA +V L+K K+ ITLAIGD Sbjct: 770 ----KPREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGD 825 Query: 894 GANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRY 953 GANDV+MI AH+G+G+ G+EG QA +SDY+ +F++L+++LLVHG + YIR+ + ++Y Sbjct: 826 GANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQY 885 Query: 954 FFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSL 1013 FFYKN F F Y FF G+S QT Y+ ++TLYN+ +TSLP+LL L++Q V + Sbjct: 886 FFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLK 945 Query: 1014 RFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL----QTVGQDGEAPSDY 1069 R P LY ++ L ++ F L G+ +++ FF GAY TV +G+ ++ Sbjct: 946 RDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFF---GAYFVFENTTVTSNGQIFGNW 1002 Query: 1070 QSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSA 1129 +F + + +V TV ++ LDT YWT++N F I+GS+ Y ++F G+ F + Sbjct: 1003 -TFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFY--VVFSLLWGGVIWPFLNY 1059 Query: 1130 FQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEE 1189 + L WL I+L V + LLP V + L +WP+ ++++Q + L E+ Sbjct: 1060 QRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQTKSQCLSVEQ 1119 >gi|150421681 ATPase, class VI, type 11A isoform b [Homo sapiens] Length = 1191 Score = 613 bits (1582), Expect = e-175 Identities = 389/1130 (34%), Positives = 606/1130 (53%), Gaps = 105/1130 (9%) Query: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150 +Y +N I + KY + FIP NLFEQF+R AN YFL + ++Q + T T+ +PL Sbjct: 44 RYPDNRIVSSKYTFWNFIPKNLFEQFRRVANFYFLIIFLVQLIIDTPTSP-VTSGLPLFF 102 Query: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPA 210 V+ VTAIK +D RHK D +N I+ G+ + ++++VGD++ +K+++ P Sbjct: 103 VITVTAIKQGYEDWLRHKADNAMNQCPVHFIQHGKLVRKQSRKLRVGDIVMVKEDETFPC 162 Query: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270 D++ LSS+ + C+V TA LDGE++ K +++ T + ED + IECE+P Sbjct: 163 DLIFLSSNRGDGTCHVTTASLDGESSHKTHYAVQDTKGFHTEED-IGGLHATIECEQPQP 221 Query: 271 RLDKFTGTLFWRN-----TSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGK 325 L KF G + + PL ++ +LLRG ++NT+ G+ I+ G +TK+ N Sbjct: 222 DLYKFVGRINVYSDLNDPVVRPLGSENLLLRGATLKNTEKIFGVAIYTGMETKMALNYQS 281 Query: 326 TRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQ-VGNSSWYLYDGEDDTPS-- 382 KR+ ++ MN + +LI + + W+++ + WY E + Sbjct: 282 KSQKRSAVEKSMNAFLIVYLCILISKALINTVLKYMWQSEPFRDEPWYNQKTESERQRNL 341 Query: 383 -YRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441 + F F ++++ N ++P+S+YV+VE+ + S+FI WD M+ E T+ L Sbjct: 342 FLKAFTDFLAFMVLFNYIIPVSMYVTVEMQKFLGSYFITWDEDMFDEETGEGPLVNTSDL 401 Query: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQH---NHNKIEQVDFSWN 498 NE+LGQ+ YIF+DKTGTLT+N M FK+CCI G +Y H + + I+ +D S + Sbjct: 402 NEELGQVEYIFTDKTGTLTENNMEFKECCIEGHVYVPHVICNGQVLPESSGIDMIDSSPS 461 Query: 499 TYADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMV---DRTDGQLN-------- 547 +G+E E FF L +CHTV V D DG Sbjct: 462 V------------------NGRERE-ELFFRALCLCHTVQVKDDDSVDGPRKSPDGGKSC 502 Query: 548 -YQAASPDEGALVNAARNFGFAFLARTQNTITI--SELGTERTYNVLAILDFNSDRKRMS 604 Y ++SPDE ALV + GF +L N + I E ER + +L IL F+S R+RMS Sbjct: 503 VYISSSPDEVALVEGVQRLGFTYLRLKDNYMEILNRENHIER-FELLEILSFDSVRRRMS 561 Query: 605 IIVRTPEGNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEK 664 +IV++ G I L+CKGAD+ I+ R+ + + + ++ A E LRTLC+ YK + ++ Sbjct: 562 VIVKSATGEIYLFCKGADSSIFPRV--IEGKVDQIRARVERNAVEGLRTLCVAYKRLIQE 619 Query: 665 EFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKA 724 E+ K AA VA +R++ L + YE+IEKDL LLGATA+ED+LQ+ +TI L KA Sbjct: 620 EYEGICKLLQAAKVALQDREKKLAEAYEQIEKDLTLLGATAVEDRLQEKAADTIEALQKA 679 Query: 725 DIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFAP 784 IK+WVLTGDK ETA +AC+L +T + L R+E Q ++ Sbjct: 680 GIKVWVLTGDKMETAAATCYACKLFRRNTQLL------ELTTKRIEEQSLHDVLFELSKT 733 Query: 785 PVQESFFPPGGNRA----------LIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRM 834 ++ S N + LII G+ L+ I+ Sbjct: 734 VLRHSGSLTRDNLSGLSADMQDYGLIIDGAALSLIM------------------------ 769 Query: 835 RTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKK-AITLAIGD 893 K R + ++ F+++ CSAV+CCR+ P QKA +V L+K K+ ITLAIGD Sbjct: 770 ----KPREDGSSGNYRELFLEICRSCSAVLCCRMAPLQKAQIVKLIKFSKEHPITLAIGD 825 Query: 894 GANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRY 953 GANDV+MI AH+G+G+ G+EG QA +SDY+ +F++L+++LLVHG + YIR+ + ++Y Sbjct: 826 GANDVSMILEAHVGIGVIGKEGRQAARNSDYAIPKFKHLKKMLLVHGHFYYIRISELVQY 885 Query: 954 FFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSL 1013 FFYKN F F Y FF G+S QT Y+ ++TLYN+ +TSLP+LL L++Q V + Sbjct: 886 FFYKNVCFIFPQFLYQFFCGFSQQTLYDTAYLTLYNISFTSLPILLYSLMEQHVGIDVLK 945 Query: 1014 RFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL----QTVGQDGEAPSDY 1069 R P LY ++ L ++ F L G+ +++ FF GAY TV +G+ ++ Sbjct: 946 RDPTLYRDVAKNALLRWRVFIYWTLLGLFDALVFFF---GAYFVFENTTVTSNGQIFGNW 1002 Query: 1070 QSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSA 1129 +F + + +V TV ++ LDT YWT++N F I+GS+ Y ++F G+ F + Sbjct: 1003 -TFGTLVFTVMVFTVTLKLALDTHYWTWINHFVIWGSLLFY--VVFSLLWGGVIWPFLNY 1059 Query: 1130 FQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQ 1179 + L WL I+L V + LLP V + L +WP+ ++++Q Sbjct: 1060 QRMYYVFIQMLSSGPAWLAIVLLVTISLLPDVLKKVLCRQLWPTATERVQ 1109 >gi|58331222 ATPase, class VI, type 11C isoform b [Homo sapiens] Length = 1119 Score = 595 bits (1533), Expect = e-169 Identities = 370/1110 (33%), Positives = 594/1110 (53%), Gaps = 101/1110 (9%) Query: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150 ++ +N I + KY + F+P NLFEQF+R AN YFL + ++Q T T+ +PL Sbjct: 42 RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSP-VTSGLPLFF 100 Query: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPA 210 V+ VTAIK +D RH+ D E+N T +I++ + + ++I+VGDV+ ++ ++ P Sbjct: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160 Query: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270 D++LLSS + CYV TA LDGE+N K ++ T E ++ T IECE+P Sbjct: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAE-SIDTLRAAIECEQPQP 219 Query: 271 RLDKFTGTLFWRNTSFP-----LDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGK 325 L KF G + + S L + +LL+G ++NT+ +G+ ++ G +TK+ N Sbjct: 220 DLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQG 279 Query: 326 TRFKRTKIDYLMN-YMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYR 384 KR+ ++ +N +++ +F++L + + + + + WY + + + + Sbjct: 280 KSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLK 339 Query: 385 G---FLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441 F F ++++ N ++P+S+YV+VE+ + S FI+WD Y E + A T+ L Sbjct: 340 VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDL 399 Query: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYA 501 NE+LGQ+ Y+F+DKTGTLT+N M F +CCI+G Y ++VD T Sbjct: 400 NEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY----------KGVTQEVDGLSQT-- 447 Query: 502 DGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMV---DRTDG-----QLNYQAASP 553 DG L ++D ++ +E F L +CHTV + D DG +L Y ++SP Sbjct: 448 DGTLTYFD-----KVDKNRE---ELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSP 499 Query: 554 DEGALVNAARNFGFAFLARTQNTITISELGTE-RTYNVLAILDFNSDRKRMSIIVRTPEG 612 DE ALV A+ +GF FL + + E Y +L L+F++ R+RMS+IV+T EG Sbjct: 500 DEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEG 559 Query: 613 NIKLYCKGADTVIYERL--HRMNPTKQETQ-DALDIFANETLRTLCLCYKEIEEKEFTEW 669 +I L+CKGAD+ ++ R+ H + TK + +A+D + RTLC+ +KEI ++ Sbjct: 560 DILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGY-----RTLCVAFKEIAPDDYERI 614 Query: 670 NKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIW 729 N++ + A +A +R+E ++KV+++IE ++ L+GATA+EDKLQD ETI L A +K+W Sbjct: 615 NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674 Query: 730 VLTGDKKETAENIGFACELLTEDT--------TICYGEDINSLLHARMENQRNRGGVYAK 781 VLTGDK ETA++ +AC L +T TI E LH + R + + + Sbjct: 675 VLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKK--LLHE 732 Query: 782 FAPPVQESF---FPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQS 838 F P SF + LII GS L+ IL + Sbjct: 733 F-PKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQ------------------------ 767 Query: 839 KRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYK-KAITLAIGDGAND 897 ++ + F+ + +C+AV+CCR+ P QKA +V +VK K ITL+IGDGAND Sbjct: 768 ----DSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGAND 823 Query: 898 VNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYK 957 V+MI +H+G+GI G+EG QA +SDYS +F++L++LLL HG Y+R+ ++YFFYK Sbjct: 824 VSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYK 883 Query: 958 NFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPG 1017 N F L F Y FF G+S Q Y+ ++T+YN+ +TSLP+L LL+Q ++ P Sbjct: 884 NLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPR 943 Query: 1018 LYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL----QTVGQDGEAPSDYQSFA 1073 LY+ + + F + FF G Y ++ ++G+ ++ +F Sbjct: 944 LYMKISGNAMLQLGPFLYWTFLAAFEGTVFFF---GTYFLFQTASLEENGKVYGNW-TFG 999 Query: 1074 VTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFT 1133 + + LV TV ++ LDT +WT++N F I+GS+A Y + F F GI F + Sbjct: 1000 TIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMY 1057 Query: 1134 GTASNALRQPYIWLTIILTVAVCLLPVVAI 1163 + L WL IIL + + L P + + Sbjct: 1058 FVFAQMLSSVSTWLAIILLIFISLFPEILL 1087 >gi|40316839 ATPase, class VI, type 11C isoform a [Homo sapiens] Length = 1132 Score = 595 bits (1533), Expect = e-169 Identities = 370/1110 (33%), Positives = 594/1110 (53%), Gaps = 101/1110 (9%) Query: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150 ++ +N I + KY + F+P NLFEQF+R AN YFL + ++Q T T+ +PL Sbjct: 42 RFCDNRIVSSKYTLWNFLPKNLFEQFRRIANFYFLIIFLVQVTVDTPTSP-VTSGLPLFF 100 Query: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPA 210 V+ VTAIK +D RH+ D E+N T +I++ + + ++I+VGDV+ ++ ++ P Sbjct: 101 VITVTAIKQGYEDWLRHRADNEVNKSTVYIIENAKRVRKESEKIKVGDVVEVQADETFPC 160 Query: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270 D++LLSS + CYV TA LDGE+N K ++ T E ++ T IECE+P Sbjct: 161 DLILLSSCTTDGTCYVTTASLDGESNCKTHYAVRDTIALCTAE-SIDTLRAAIECEQPQP 219 Query: 271 RLDKFTGTLFWRNTSFP-----LDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGK 325 L KF G + + S L + +LL+G ++NT+ +G+ ++ G +TK+ N Sbjct: 220 DLYKFVGRINIYSNSLEAVARSLGPENLLLKGATLKNTEKIYGVAVYTGMETKMALNYQG 279 Query: 326 TRFKRTKIDYLMN-YMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYR 384 KR+ ++ +N +++ +F++L + + + + + WY + + + + Sbjct: 280 KSQKRSAVEKSINAFLIVYLFILLTKAAVCTTLKYVWQSTPYNDEPWYNQKTQKERETLK 339 Query: 385 G---FLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441 F F ++++ N ++P+S+YV+VE+ + S FI+WD Y E + A T+ L Sbjct: 340 VLKMFTDFLSFMVLFNFIIPVSMYVTVEMQKFLGSFFISWDKDFYDEEINEGALVNTSDL 399 Query: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYA 501 NE+LGQ+ Y+F+DKTGTLT+N M F +CCI+G Y ++VD T Sbjct: 400 NEELGQVDYVFTDKTGTLTENSMEFIECCIDGHKY----------KGVTQEVDGLSQT-- 447 Query: 502 DGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMV---DRTDG-----QLNYQAASP 553 DG L ++D ++ +E F L +CHTV + D DG +L Y ++SP Sbjct: 448 DGTLTYFD-----KVDKNRE---ELFLRALCLCHTVEIKTNDAVDGATESAELTYISSSP 499 Query: 554 DEGALVNAARNFGFAFLARTQNTITISELGTE-RTYNVLAILDFNSDRKRMSIIVRTPEG 612 DE ALV A+ +GF FL + + E Y +L L+F++ R+RMS+IV+T EG Sbjct: 500 DEIALVKGAKRYGFTFLGNRNGYMRVENQRKEIEEYELLHTLNFDAVRRRMSVIVKTQEG 559 Query: 613 NIKLYCKGADTVIYERL--HRMNPTKQETQ-DALDIFANETLRTLCLCYKEIEEKEFTEW 669 +I L+CKGAD+ ++ R+ H + TK + +A+D + RTLC+ +KEI ++ Sbjct: 560 DILLFCKGADSAVFPRVQNHEIELTKVHVERNAMDGY-----RTLCVAFKEIAPDDYERI 614 Query: 670 NKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIW 729 N++ + A +A +R+E ++KV+++IE ++ L+GATA+EDKLQD ETI L A +K+W Sbjct: 615 NRQLIEAKMALQDREEKMEKVFDDIETNMNLIGATAVEDKLQDQAAETIEALHAAGLKVW 674 Query: 730 VLTGDKKETAENIGFACELLTEDT--------TICYGEDINSLLHARMENQRNRGGVYAK 781 VLTGDK ETA++ +AC L +T TI E LH + R + + + Sbjct: 675 VLTGDKMETAKSTCYACRLFQTNTELLELTTKTIEESERKEDRLHELLIEYRKK--LLHE 732 Query: 782 FAPPVQESF---FPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQS 838 F P SF + LII GS L+ IL + Sbjct: 733 F-PKSTRSFKKAWTEHQEYGLIIDGSTLSLILNSSQ------------------------ 767 Query: 839 KRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYK-KAITLAIGDGAND 897 ++ + F+ + +C+AV+CCR+ P QKA +V +VK K ITL+IGDGAND Sbjct: 768 ----DSSSNNYKSIFLQICMKCTAVLCCRMAPLQKAQIVRMVKNLKGSPITLSIGDGAND 823 Query: 898 VNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYK 957 V+MI +H+G+GI G+EG QA +SDYS +F++L++LLL HG Y+R+ ++YFFYK Sbjct: 824 VSMILESHVGIGIKGKEGRQAARNSDYSVPKFKHLKKLLLAHGHLYYVRIAHLVQYFFYK 883 Query: 958 NFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPG 1017 N F L F Y FF G+S Q Y+ ++T+YN+ +TSLP+L LL+Q ++ P Sbjct: 884 NLCFILPQFLYQFFCGFSQQPLYDAAYLTMYNICFTSLPILAYSLLEQHINIDTLTSDPR 943 Query: 1018 LYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL----QTVGQDGEAPSDYQSFA 1073 LY+ + + F + FF G Y ++ ++G+ ++ +F Sbjct: 944 LYMKISGNAMLQLGPFLYWTFLAAFEGTVFFF---GTYFLFQTASLEENGKVYGNW-TFG 999 Query: 1074 VTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFT 1133 + + LV TV ++ LDT +WT++N F I+GS+A Y + F F GI F + Sbjct: 1000 TIVFTVLVFTVTLKLALDTRFWTWINHFVIWGSLAFY--VFFSFFWGGIIWPFLKQQRMY 1057 Query: 1134 GTASNALRQPYIWLTIILTVAVCLLPVVAI 1163 + L WL IIL + + L P + + Sbjct: 1058 FVFAQMLSSVSTWLAIILLIFISLFPEILL 1087 >gi|65301139 ATPase, class II, type 9A [Homo sapiens] Length = 1047 Score = 411 bits (1057), Expect = e-114 Identities = 321/1119 (28%), Positives = 529/1119 (47%), Gaps = 150/1119 (13%) Query: 88 KESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVP 147 ++ +Y N I KYN FTF+P LF QFK NLYFL L Q VP++ A YT VP Sbjct: 49 RDQRYPRNVINNQKYNFFTFLPGVLFNQFKYFFNLYFLLLACSQFVPEMRLGALYTYWVP 108 Query: 148 LLVVLGVTAIKDLVDDVARHKMDKEINNRT-CEVIKDGRFKVAKWKEIQVGDVIRLKKND 206 L VL VT I++ V+++ + DKE+N++ + G KV K IQVGD+I ++KN Sbjct: 109 LGFVLAVTVIREAVEEIRCYVRDKEVNSQVYSRLTARGTVKV-KSSNIQVGDLIIVEKNQ 167 Query: 207 FVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECE 266 VPAD++ L +SE N C++ T +LDGET+ K ++ + T Q L L ++ E Sbjct: 168 RVPADMIFLRTSEKNGSCFLRTDQLDGETDWKLRLPVACT-QRLPTAADLLQIRSYVYAE 226 Query: 267 EPNNRLDKFTGTLFWRNTSFP-----LDADKILLRGCVIRNTDFCHGLVIFAGADTKIMK 321 EPN + F GT F R S P L + L G V+ + G+V++ G + + + Sbjct: 227 EPNIDIHNFVGT-FTREDSDPPISESLSIENTLWAGTVVASGTVV-GVVLYTGRELRSVM 284 Query: 322 NSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTP 381 N+ R K D +N + +F L+++S + Q WYL Sbjct: 285 NTSNPRSKIGLFDLEVNCLTKILFGALVVVSLVMV------ALQHFAGRWYLQ------- 331 Query: 382 SYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441 ++++ + ++PISL V++++ ++ S I D K R++T+ Sbjct: 332 -------IIRFLLLFSNIIPISLRVNLDMGKIVYSWVIRRD------SKIPGTVVRSSTI 378 Query: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYG-DHRDASQHNHNKIEQVDFSWNTY 500 EQLG+I Y+ +DKTGTLTQN M FK+ + YG D D Q + I + Sbjct: 379 PEQLGRISYLLTDKTGTLTQNEMIFKRLHLGTVAYGLDSMDEVQSHIFSI------YTQQ 432 Query: 501 ADGKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTV--------MVDRTDGQLN----- 547 + A L +++ V + +A+CH V + D+ + + Sbjct: 433 SQDPPAQKGPTLTTKVRRTMSSRVHEAVKAIALCHNVTPVYESNGVTDQAEAEKQYEDSC 492 Query: 548 --YQAASPDEGALVNAARNFGFAFLARTQNTITISELGTE-RTYNVLAILDFNSDRKRMS 604 YQA+SPDE ALV + G + R Q+++ + G + + +L I F + KRM Sbjct: 493 RVYQASSPDEVALVQWTESVGLTLVGRDQSSMQLRTPGDQILNFTILQIFPFTYESKRMG 552 Query: 605 IIVRTPE-GNIKLYCKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEE 663 IIVR G I Y KGAD V+ + + ++E + A E LR L + K + E Sbjct: 553 IIVRDESTGEITFYMKGADVVMAGIVQYNDWLEEECGN----MAREGLRVLVVAKKSLAE 608 Query: 664 KEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAK 723 +++ ++ +++ A ++ +R + V E +E ++ LL T +ED+LQ V T+ L Sbjct: 609 EQYQDFEARYVQAKLSVHDRSLKVATVIESLEMEMELLCLTGVEDQLQADVRPTLETLRN 668 Query: 724 ADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFA 783 A IK+W+LTGDK ETA L+T + +DI+ NRG + Sbjct: 669 AGIKVWMLTGDKLETATCTAKNAHLVTRN------QDIHV-----FRLVTNRGEAH---- 713 Query: 784 PPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLE 843 ++ + F + AL+I+G LE Sbjct: 714 --LELNAFRRKHDCALVISGD------------------------------------SLE 735 Query: 844 AKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKT 903 + + F++LAC+C AV+CCR P QKA +V L++ +T A+GDG NDV+MI+ Sbjct: 736 VCLKYYEYEFMELACQCPAVVCCRCAPTQKAQIVRLLQERTGKLTCAVGDGGNDVSMIQE 795 Query: 904 AHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRYFFYKNFAFTL 963 + GVG+ G+EG QA +++D+S QF++L RLL+VHGR SY R ++ +++ + Sbjct: 796 SDCGVGVEGKEGKQASLAADFSITQFKHLGRLLMVHGRNSYKRSAALSQFVIHRSLCIST 855 Query: 964 VHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQ 1023 + +S +++ Y+ + I Y+ +YT PV + +LD+DV ++++ +P LY Sbjct: 856 MQAVFSSVFYFASVPLYQGFLIIGYSTIYTMFPVFSL-VLDKDVKSEVAMLYPELY---- 910 Query: 1024 RDLL----FNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQSFAVTIASA 1079 +DLL +YK F + +L + + + GA L S++ ++ Sbjct: 911 KDLLKGRPLSYKTFLIWVLISIYQGSTIMY---GALLL-------FESEFVHIVAISFTS 960 Query: 1080 LVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAFQFTGTASNA 1139 L++T + L W ++ + S+A Y + H I V F + F Sbjct: 961 LILTELLMVALTIQTWHWLMTVAELLSLACYIASLVFLHEF-IDVYFIATLSF------- 1012 Query: 1140 LRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKI 1178 +W ++T+ C LP+ +++L P K+ Sbjct: 1013 -----LWKVSVITLVSC-LPLYVLKYLRRRFSPPSYSKL 1045 >gi|41327760 ATPase, class II, type 9B [Homo sapiens] Length = 1147 Score = 402 bits (1032), Expect = e-111 Identities = 319/1136 (28%), Positives = 527/1136 (46%), Gaps = 163/1136 (14%) Query: 89 ESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPL 148 E K+ N+IK KYN FTFIP L+EQFK NLYFL + Q VP + YT PL Sbjct: 127 EEKHPRNSIKNQKYNVFTFIPGVLYEQFKFFLNLYFLVISCSQFVPALKIGYLYTYWAPL 186 Query: 149 LVVLGVTAIKDLVDDVARHKMDKEINNRT-CEVIKDGRFKVAKWKEIQVGDVIRLKKNDF 207 VL VT ++ +D+ R + DKE+N++ ++ G+ +V K +IQVGD+I ++KN Sbjct: 187 GFVLAVTMTREAIDEFRRFQRDKEVNSQLYSKLTVRGKVQV-KSSDIQVGDLIIVEKNQR 245 Query: 208 VPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEE 267 +P+D++ L +SE C++ T +LDGET+ K K+++ T Q L L + ++ ++ Sbjct: 246 IPSDMVFLRTSEKAGSCFIRTDQLDGETDWKLKVAVSCTQQ-LPALGDLFSISAYVYAQK 304 Query: 268 PNNRLDKFTGTLFWRNTSFP-----------LDADKILLRGCVIRNTDFCHGLVIFAGAD 316 P + F GT F R S P L A I+ G VI G+VI+ G + Sbjct: 305 PQMDIHSFEGT-FTREDSDPPIHESLSIENTLWASTIVASGTVI-------GVVIYTGKE 356 Query: 317 TKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDG 376 T+ + N+ + K +D +N + +F+ L+ LS + + VG Sbjct: 357 TRSVMNTSNPKNKVGLLDLELNRLTKALFLALVALSIVMVTLQGF----VG--------- 403 Query: 377 EDDTPSYRGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAK- 435 P YR F +++ + ++PISL V+++ +G++ + W M +++ P Sbjct: 404 ----PWYRNLFRF---LLLFSYIIPISLRVNLD---MGKAVY-GW---MMMKDENIPGTV 449 Query: 436 ARTTTLNEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYG-DHRDASQ-HNHNKIEQV 493 RT+T+ E+LG++ Y+ +DKTGTLTQN M FK+ + YG D D Q H + Q+ Sbjct: 450 VRTSTIPEELGRLVYLLTDKTGTLTQNEMIFKRLHLGTVSYGADTMDEIQSHVRDSYSQM 509 Query: 494 DFSWNTYADGKLAFYD-HYLIEQIQSGKEPEVRQFFFLLAVCHTVM-------------- 538 G +++ + + + +CH V Sbjct: 510 QSQAGGNNTGSTPLRKAQSSAPKVRKSVSSRIHEAVKAIVLCHNVTPVYESRAGVTEETE 569 Query: 539 -----VDRTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITI-SELGTERTYNVLA 592 D +D YQA+SPDE ALV + G ++R ++ + + G ++ +L Sbjct: 570 FAEADQDFSDENRTYQASSPDEVALVQWTESVGLTLVSRDLTSMQLKTPSGQVLSFCILQ 629 Query: 593 ILDFNSDRKRMSIIVRTPE-GNIKLYCKGADTVIYERLHRMNPTKQET---QDALDIFAN 648 + F S+ KRM +IVR I Y KGAD M+P Q ++ A Sbjct: 630 LFPFTSESKRMGVIVRDESTAEITFYMKGADVA-------MSPIVQYNDWLEEECGNMAR 682 Query: 649 ETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIED 708 E LRTL + K + E+++ ++ ++ A ++ +R + V E +E+++ LL T +ED Sbjct: 683 EGLRTLVVAKKALTEEQYQDFESRYTQAKLSMHDRSLKVAAVVESLEREMELLCLTGVED 742 Query: 709 KLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHAR 768 +LQ V T+ L A IKIW+LTGDK ETA I + L++ I + S A Sbjct: 743 QLQADVRPTLEMLRNAGIKIWMLTGDKLETATCIAKSSHLVSRTQDIHIFRQVTSRGEAH 802 Query: 769 MENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRT 828 +E + F + AL+I+G Sbjct: 803 LE-----------------LNAFRRKHDCALVISGD------------------------ 821 Query: 829 EEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAIT 888 LE + + FV+LAC+C AV+CCR +P QKA +V L++++ T Sbjct: 822 ------------SLEVCLKYYEHEFVELACQCPAVVCCRCSPTQKARIVTLLQQHTGRRT 869 Query: 889 LAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMC 948 AIGDG NDV+MI+ A G+GI G+EG QA +++D+S QFR++ RLL+VHGR SY R Sbjct: 870 CAIGDGGNDVSMIQAADCGIGIEGKEGKQASLAADFSITQFRHIGRLLMVHGRNSYKRSA 929 Query: 949 KFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVS 1008 ++ ++ + + +S +++ Y+ + + Y +YT PV + +LDQDV Sbjct: 930 ALGQFVMHRGLIISTMQAVFSSVFYFASVPLYQGFLMVGYATIYTMFPVFSL-VLDQDVK 988 Query: 1009 DKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSD 1068 ++++ +P LY + ++K F + +L + IL + L + S+ Sbjct: 989 PEMAMLYPELYKDLTKGRSLSFKTFLIWVLISIYQGGILMYGALVLF----------ESE 1038 Query: 1069 YQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIM------FDFHSAGI 1122 + +AL++T + L W ++ + F S+ Y + F Sbjct: 1039 FVHVVAISFTALILTELLMVALTVRTWHWLMVVAEFLSLGCYVSSLAFLNEYFGIGRVSF 1098 Query: 1123 HVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKI 1178 AF T T ++W +TV C LP+ +++L + P K+ Sbjct: 1099 GAFLDVAFITTVT--------FLWKVSAITVVSC-LPLYVLKYLRRKLSPPSYCKL 1145 >gi|222352161 ATPase, class V, type 10D [Homo sapiens] Length = 1426 Score = 390 bits (1001), Expect = e-108 Identities = 244/660 (36%), Positives = 366/660 (55%), Gaps = 52/660 (7%) Query: 546 LNYQAASPDEGALVNAARNFGFAFLARTQNTITI--SELGTERTYNVLAILDFNSDRKRM 603 L Y+A SPDE ALV AAR + +RT + + + LG T+ +L IL F+S RKRM Sbjct: 721 LCYEAESPDEAALVYAARAYQCTLRSRTPEQVMVDFAALGP-LTFQLLHILPFDSVRKRM 779 Query: 604 SIIVRTPEGN-IKLYCKGADTVIYERLHRMNP-----------TKQETQDALDIFANETL 651 S++VR P N + +Y KGAD+VI E L +P +++TQ LD +A + L Sbjct: 780 SVVVRHPLSNQVVVYTKGADSVIMELLSVASPDGASLEKQQMIVREKTQKHLDDYAKQGL 839 Query: 652 RTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQ 711 RTLC+ K + + E+ EW + A + NR+E L + +E L LLGAT IED+LQ Sbjct: 840 RTLCIAKKVMSDTEYAEWLRNHFLAETSIDNREELLLESAMRLENKLTLLGATGIEDRLQ 899 Query: 712 DGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHARMEN 771 +GVPE+I L KA IKIW+LTGDK+ETA NI +AC+LL D + L ++ Sbjct: 900 EGVPESIEALHKAGIKIWMLTGDKQETAVNIAYACKLLEPD---------DKLFILNTQS 950 Query: 772 QRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRNKILKLKFPRTEEE 831 + G + + +Q+ + L E+ + +L+ PR Sbjct: 951 KDACGMLMSTILKELQKK-----------------TQALPEQVSLSEDLLQPPVPRDSGL 993 Query: 832 RRMRTQSKRRLE-AKKEQRQKNFVDLACECSAVICCRVTPKQKAMVVDLVKRYKKAITLA 890 R + + LE A +E QK F++L C AV+CCR TP QK+ VV LV+ + + +TLA Sbjct: 994 RAGLIITGKTLEFALQESLQKQFLELTSWCQAVVCCRATPLQKSEVVKLVRSHLQVMTLA 1053 Query: 891 IGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKF 950 IGDGANDV+MI+ A IG+G+SGQEGMQAVM+SD++ +QF++L +LLLVHG W Y R+ Sbjct: 1054 IGDGANDVSMIQVADIGIGVSGQEGMQAVMASDFAVSQFKHLSKLLLVHGHWCYTRLSNM 1113 Query: 951 LRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDK 1010 + YFFYKN A+ + FWY FF G+S + + W + +N+L+TS P ++ G+L++DVS + Sbjct: 1114 ILYFFYKNVAYVNLLFWYQFFCGFSGTSMTDYWVLIFFNLLFTSAPPVIYGVLEKDVSAE 1173 Query: 1011 LSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYLQTVGQDGEAPSDYQ 1070 ++ P LY GQ+ + F+++LL S++ FF+P Y G D +D Sbjct: 1174 TLMQLPELYRSGQKSEAYLPHTFWITLLDAFYQSLVCFFVP---YFTYQGSD----TDIF 1226 Query: 1071 SFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFDFHSAGIHVLFPSAF 1130 +F + +A + V + +++ T+++ I GSI YF F + + PS Sbjct: 1227 AFGNPLNTAALFIVLLHLVIESKSLTWIHLLVIIGSILSYFLFAIVFGAMCVTCNPPSNP 1286 Query: 1131 QFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESDKIQKHRKRLKAEEQ 1190 + + P +L ILT ++ LLP R L +++PS + KH RL EE+ Sbjct: 1287 YW--IMQEHMLDPVFYLVCILTTSIALLPRFVYRVLQGSLFPSPILR-AKHFDRLTPEER 1343 Score = 311 bits (797), Expect = 2e-84 Identities = 164/399 (41%), Positives = 248/399 (62%), Gaps = 11/399 (2%) Query: 92 YANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVV 151 Y NN I+T KY F+P NLFEQF RAANLYFL L++L VP + T++PL+VV Sbjct: 71 YVNNRIRTTKYTLLNFVPRNLFEQFHRAANLYFLFLVVLNWVPLVEAFQKEITMLPLVVV 130 Query: 152 LGVTAIKDLVDDVARHKMDKEINNRTCEVI--KDGRFKVAKWKEIQVGDVIRLKKNDFVP 209 L + AIKD ++D ++K+DK+INN +V K+ ++ WK++ VGD IRL N+ +P Sbjct: 131 LTIIAIKDGLEDYRKYKIDKQINNLITKVYSRKEKKYIDRCWKDVTVGDFIRLSCNEVIP 190 Query: 210 ADILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTL--ATFDGFIECEE 267 AD++LL S++P+ +C++ET+ LDGE+NLK + ++ Y +++ + F IECE Sbjct: 191 ADMVLLFSTDPDGICHIETSGLDGESNLKQR---QVVRGYAEQDSEVDPEKFSSRIECES 247 Query: 268 PNNRLDKFTGTLFWRNTS-FPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKT 326 PNN L +F G L N L + +LLRGC IRNT+ G+V++AG +TK M N+ Sbjct: 248 PNNDLSRFRGFLEHSNKERVGLSKENLLLRGCTIRNTEAVVGIVVYAGHETKAMLNNSGP 307 Query: 327 RFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLY---DGEDDTPSY 383 R+KR+K++ N V ++L+++ A+GH W ++ ++ DG +P Sbjct: 308 RYKRSKLERRANTDVLWCVMLLVIMCLTGAVGHGIWLSRYEKMHFFNVPEPDGHIISPLL 367 Query: 384 RGFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNE 443 GF +FW II+L ++PISLYVS+E+++LGQ +FI D+ Y + D+ + R + E Sbjct: 368 AGFYMFWTMIILLQVLIPISLYVSIEIVKLGQIYFIQSDVDFYNEKMDSIVQCRALNIAE 427 Query: 444 QLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDA 482 LGQI Y+FSDKTGTLT+N M F++C + G Y +A Sbjct: 428 DLGQIQYLFSDKTGTLTENKMVFRRCSVAGFDYCHEENA 466 >gi|149944474 ATPase, class V, type 10B [Homo sapiens] Length = 1461 Score = 387 bits (995), Expect = e-107 Identities = 241/685 (35%), Positives = 356/685 (51%), Gaps = 83/685 (12%) Query: 548 YQAASPDEGALVNAARNFGFAFLARTQNTITIS-ELGTERTYNVLAILDFNSDRKRMSII 606 Y+A SPDE ALV+AA + F ++RT +T+ GT T+++L L F+S RKRMS++ Sbjct: 717 YEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQGTCLTFSLLCTLGFDSVRKRMSVV 776 Query: 607 VRTP-EGNIKLYCKGADTVIYERLH------------RMNPTKQETQDALDIFANETLRT 653 VR P G I +Y KGAD+VI + L ++ + TQ LD++A + LRT Sbjct: 777 VRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRT 836 Query: 654 LCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDG 713 LC+ K + E++F W A + NRDE L + + +E L LLGAT IED+LQ+G Sbjct: 837 LCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEG 896 Query: 714 VPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTI----------------CY 757 VP+TI+ L +A I++WVLTGDK+ETA NI +C LL + T+ C Sbjct: 897 VPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCA 956 Query: 758 GEDINSLLHARMENQRNRGGVYAKFAPPV-QESFFPPGGNRALIITGSWLNEILLEKKTK 816 E++ + +++ G P + E+ P G L+I G LN I K Sbjct: 957 LEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAG---LVIDGKTLNAIFQGKL-- 1011 Query: 817 RNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMV 876 +K F++L C +V+CCR TP QK+M+ Sbjct: 1012 ---------------------------------EKKFLELTQYCRSVLCCRSTPLQKSMI 1038 Query: 877 VDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYLQRLL 936 V LV+ + +TL+IGDGANDV+MI+ A IG+GISGQEGMQAVMSSD++ +F++L++LL Sbjct: 1039 VKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLL 1098 Query: 937 LVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLP 996 LVHG W Y R+ + + Y+ YKN + + FWY FF G+S+ T + W + +N+ +TSLP Sbjct: 1099 LVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLP 1158 Query: 997 VLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPLGAYL 1056 L+ G+LD+D+S + L P LY GQ +N F++S++ S+I FFIP YL Sbjct: 1159 PLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIP---YL 1215 Query: 1057 QTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFGIMFD 1116 G D D +F I + + T+ ++ WT + + GS +YF + Sbjct: 1216 AYKGSD----IDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLL 1271 Query: 1117 FHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWPSESD 1176 +++ + P+ + L P +L LT V LLP L T S Sbjct: 1272 YNATCVICNSPTNPYW--VMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLIS 1329 Query: 1177 KIQK-----HRKRLKAEEQWQRRQQ 1196 K QK KR + W+ RQ+ Sbjct: 1330 KAQKIDKLPPDKRNLEIQSWRSRQR 1354 Score = 307 bits (786), Expect = 5e-83 Identities = 176/420 (41%), Positives = 248/420 (59%), Gaps = 14/420 (3%) Query: 91 KYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLV 150 +Y N T KY FTF+P NLFEQF R ANLYFL L+IL +P + T++PL + Sbjct: 65 RYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAI 124 Query: 151 VLGVTAIKDLVDDVARHKMDKEINNRTCEVI--KDGRFKVAKWKEIQVGDVIRLKKNDFV 208 VL V IKD ++D RH+ DK IN + K+ + WK+++VGD I++K N+ V Sbjct: 125 VLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIV 184 Query: 209 PADILLLSSSEPNSLCYVETAELDGETNLKFKMSLE-ITDQYLQREDTLATFDGFIECEE 267 PADILLL SS+PN +C++ETA LDGETNLK + ++ + Q +Q E L F I CE+ Sbjct: 185 PADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPEL--FHNTIVCEK 242 Query: 268 PNNRLDKFTGTLFWRN-TSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKT 326 PNN L+KF G + + T + +LLRGC IRNT+ G+VI+AG +TK M N+ Sbjct: 243 PNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGP 302 Query: 327 RFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEAQVGNSSWYLYDGEDDTPSYR-- 384 R+KR+KI+ MN ++ +LIL+ A+GH+ W +D D S+ Sbjct: 303 RYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHP--PFDVPDANGSFLPS 360 Query: 385 ---GFLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTL 441 GF +F II+L ++PISLYVS+E+++LGQ F++ DL +Y E D + R + Sbjct: 361 ALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNI 420 Query: 442 NEQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQ-HNHNKIEQVDFSWNTY 500 E LGQI YIFSDKTGTLT+N M F++C I G Y +A + +++ W Y Sbjct: 421 AEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQY 480 >gi|14424433 ATPase, class V, type 10A [Homo sapiens] Length = 1499 Score = 381 bits (979), Expect = e-105 Identities = 243/729 (33%), Positives = 386/729 (52%), Gaps = 76/729 (10%) Query: 542 TDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITIS--ELGTERTYNVLAILDFNSD 599 ++ +L Y+A SPDE ALV AAR + + R + +++ LG T+ +L L F+S Sbjct: 687 SERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLG-RLTFELLHTLGFDSV 745 Query: 600 RKRMSIIVRTP-EGNIKLYCKGADTVIYERLH----------RMNPTKQETQDALDIFAN 648 RKRMS+++R P I +Y KGAD+V+ + L + +TQ+ L+++A Sbjct: 746 RKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAA 805 Query: 649 ETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIED 708 E LRTLC+ + + ++E+ W + + A + N +E L + +E +L LLGAT IED Sbjct: 806 EGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIED 865 Query: 709 KLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTICYGEDINSLLHAR 768 +LQDGVPETISKL +A ++IWVLTGDK+ETA NI +AC+LL D + + A Sbjct: 866 RLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAA 925 Query: 769 MENQ---------------RNRGGVYAKFAPPVQESFFPPGGNR-ALIITGSWLNEILLE 812 + +Q + +G V +F+ S G R +L+I G Sbjct: 926 LLDQCLCYVQSRGLQRAPEKTKGKVSMRFSSLCPPSTSTASGRRPSLVIDG--------- 976 Query: 813 KKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQ 872 R + ++ LE K F+ LA +C +V+CCR TP Q Sbjct: 977 -------------------RSLAYALEKNLEDK-------FLFLAKQCRSVLCCRSTPLQ 1010 Query: 873 KAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQAVMSSDYSFAQFRYL 932 K+MVV LV+ KA+TLAIGDGANDV+MI+ A +GVGISGQEGMQAVM+SD++ +FRYL Sbjct: 1011 KSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYL 1070 Query: 933 QRLLLVHGRWSYIRMCKFLRYFFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLY 992 +RLL++HG W Y R+ + YFFYKN F + FW+ FF G+SA T + W++ +N+L+ Sbjct: 1071 ERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLF 1130 Query: 993 TSLPVLLMGLLDQDVSDKLSLRFPGLYIVGQRDLLFNYKRFFVSLLHGVLTSMILFFIPL 1052 +SLP L+ G+LD+DV + L P LY GQ + + F+ ++ S++ F IP Sbjct: 1131 SSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPY 1190 Query: 1053 GAYLQTVGQDGEAPSDYQSFAVTIASALVITVNFQIGLDTSYWTFVNAFSIFGSIALYFG 1112 AY ++ D ++ I + ++T +G++T WT++N + S+ L+F Sbjct: 1191 LAYY-------DSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFT 1243 Query: 1113 IMFDFHSAGIHVLFPSAFQFTGTASNALRQPYIWLTIILTVAVCLLPVVAIRFLSMTIWP 1172 + ++A +P + + T L P +LT ++T LLP + R L ++P Sbjct: 1244 VAL-IYNASCATCYPPSNPY-WTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFP 1301 Query: 1173 SESDKIQKHRKRLKAEEQWQRRQQVFRRGVSTRRSAYAFSHQRGYADLISSGRSIRKKRS 1232 ++ ++ + K+ + ++ F +G + S S R + + + Sbjct: 1302 TQLQLARQLTR--KSPRRCSAPKETFAQGRLPKDSGTEHSSGRTVKTSVPLSQPSWHTQQ 1359 Query: 1233 PLDAIVADG 1241 P+ ++ A G Sbjct: 1360 PVCSLEASG 1368 Score = 313 bits (802), Expect = 7e-85 Identities = 170/399 (42%), Positives = 243/399 (60%), Gaps = 8/399 (2%) Query: 93 ANNAIKTYKYNAFTFIPMNLFEQFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVL 152 A+N +KT KY +F+P NLFEQF R AN+YF+ + +L VP ++ L P+L +L Sbjct: 60 ADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFIL 119 Query: 153 GVTAIKDLVDDVARHKMDKEINNRTCEVIKDGRFKVAK--WKEIQVGDVIRLKKNDFVPA 210 +TA +DL +D +RH+ D +IN+ C V K WKEI VGD +RL+ N+ PA Sbjct: 120 AITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPA 179 Query: 211 DILLLSSSEPNSLCYVETAELDGETNLKFKMSLEITDQYLQREDTLATFDGFIECEEPNN 270 DILLLSSS+P+ LC++ETA LDGETNLK + + + + + L TF IECE+PNN Sbjct: 180 DILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPL-TFTSVIECEKPNN 238 Query: 271 RLDKFTGTLFWRN-TSFPLDADKILLRGCVIRNTDFCHGLVIFAGADTKIMKNSGKTRFK 329 L +F G + N L + +LLRGC +RNTD G+VI+AG +TK + N+ R+K Sbjct: 239 DLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYK 298 Query: 330 RTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYW--EAQVGNSSWYL--YDGEDDTPSYRG 385 R+K++ MN V ++L+ +S A+GH W Q S +Y+ DG +P Sbjct: 299 RSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAA 358 Query: 386 FLIFWGYIIVLNTMVPISLYVSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQL 445 F IIVL ++PISLYVS+E+++ Q +FIN D+Q+Y E D+ + R + E L Sbjct: 359 VYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDL 418 Query: 446 GQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQ 484 GQI YIFSDKTGTLT+N M F++C ++G Y +A + Sbjct: 419 GQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQR 457 >gi|55743077 ATPase, class I, type 8B, member 2 isoform b [Homo sapiens] Length = 387 Score = 377 bits (968), Expect = e-104 Identities = 193/369 (52%), Positives = 261/369 (70%), Gaps = 17/369 (4%) Query: 65 QVKANDRKYHEQPHFMNTKFLCIKESKYANNAIKTYKYNAFTFIPMNLFEQFKRAANLYF 124 + +ANDR+Y+E KF +YA+N IKT KYN TF+P+NLFEQF+ AN YF Sbjct: 15 RARANDREYNE-------KF------QYASNCIKTSKYNILTFLPVNLFEQFQEVANTYF 61 Query: 125 LALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEINNRTCEVIKDG 184 L LLILQ +PQIS+L+W+TT+VPL++VL +TA+KD DD RHK D ++NNR +V+ +G Sbjct: 62 LFLLILQLIPQISSLSWFTTIVPLVLVLTITAVKDATDDYFRHKSDNQVNNRQSQVLING 121 Query: 185 RFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKFKMSLE 244 + +W + VGD+I+L+ N FV AD+LLLSSSEP+ LCY+ETAELDGETN+K + ++ Sbjct: 122 ILQQEQWMNVCVGDIIKLENNQFVAADLLLLSSSEPHGLCYIETAELDGETNMKVRQAIP 181 Query: 245 ITDQYLQREDTLATFDGFIECEEPNNRLDKFTGTLFWRNTSFPLDADKILLRGCVIRNTD 304 +T + L LA FDG + CE PNN+LDKF+GTL+W+ FPL +LLRGCV+RNT+ Sbjct: 182 VTSE-LGDISKLAKFDGEVICEPPNNKLDKFSGTLYWKENKFPLSNQNMLLRGCVLRNTE 240 Query: 305 FCHGLVIFAGADTKIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAGLAIGHAYWEA 364 +C GLVIFAG DTK+M+NSG+T+FKRT ID LMN +V IF L+ + LAIG+A WE Sbjct: 241 WCFGLVIFAGPDTKLMQNSGRTKFKRTSIDRLMNTLVLWIFGFLVCMGVILAIGNAIWEH 300 Query: 365 QVG-NSSWYL-YDGEDDTPSYRGFLIFWGYIIVLNTMVPISLYVS-VEVIRLGQSHFINW 421 +VG YL +D D+ + GFL FW YII+LNT+VPISLYV V + G S Sbjct: 301 EVGMRFQVYLPWDEAVDSAFFSGFLSFWSYIIILNTVVPISLYVRYVPSLTWGLSRESGG 360 Query: 422 DLQMYYAEK 430 ++++++ K Sbjct: 361 PIELFFSMK 369 >gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sapiens] Length = 1170 Score = 87.8 bits (216), Expect = 6e-17 Identities = 85/337 (25%), Positives = 134/337 (39%), Gaps = 73/337 (21%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E +G I SDKTGTLT N MT + I G Y +I D D Sbjct: 454 ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHY-----------RQIPSPDVFLPKVLD 502 Query: 503 GKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAA 562 ++ I A ++ +G L Q + E AL+ Sbjct: 503 --------LIVNGISINS-----------AYTSKILPPEKEGGLPRQVGNKTECALL--- 540 Query: 563 RNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGAD 622 GF + +E+ E+ Y V FNS RK MS ++R P G ++Y KGA Sbjct: 541 ---GFVTDLKQDYQAVRNEVPEEKLYKVYT---FNSVRKSMSTVIRNPNGGFRMYSKGAS 594 Query: 623 TVIYERLHRMNPTKQE------------TQDALDIFANETLRTLCLCYKEIEEKEFTEWN 670 +I + +R+ K E + ++ A + LRT+C+ Y++ ++ E W+ Sbjct: 595 EIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE-PSWD 653 Query: 671 KKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWV 730 + EI +L + IED ++ VP+ I+K +A I + + Sbjct: 654 NE-------------------NEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRM 694 Query: 731 LTGDKKETAENIGFACELLT--EDTTICYGEDINSLL 765 +TGD TA I C +LT +D G++ N L+ Sbjct: 695 VTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI 731 Score = 33.9 bits (76), Expect = 1.00 Identities = 23/93 (24%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 145 LVPLLVVLGVTAIKDLVDDVARHKMDKEINN-RTCEVIKDGRFKVAKWKEIQVGDVIRLK 203 L +++V+ VTA D + + I + +I++G+ EI VGD+ ++K Sbjct: 156 LFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVK 215 Query: 204 KNDFVPADILLLSSSEPNSLCYVETAELDGETN 236 D +PAD +L+ ++ ++ + L GE++ Sbjct: 216 YGDLLPADGILIQGND----LKIDESSLTGESD 244 >gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sapiens] Length = 1205 Score = 87.8 bits (216), Expect = 6e-17 Identities = 85/337 (25%), Positives = 134/337 (39%), Gaps = 73/337 (21%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E +G I SDKTGTLT N MT + I G Y +I D D Sbjct: 454 ETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHY-----------RQIPSPDVFLPKVLD 502 Query: 503 GKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAA 562 ++ I A ++ +G L Q + E AL+ Sbjct: 503 --------LIVNGISINS-----------AYTSKILPPEKEGGLPRQVGNKTECALL--- 540 Query: 563 RNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGAD 622 GF + +E+ E+ Y V FNS RK MS ++R P G ++Y KGA Sbjct: 541 ---GFVTDLKQDYQAVRNEVPEEKLYKVYT---FNSVRKSMSTVIRNPNGGFRMYSKGAS 594 Query: 623 TVIYERLHRMNPTKQE------------TQDALDIFANETLRTLCLCYKEIEEKEFTEWN 670 +I + +R+ K E + ++ A + LRT+C+ Y++ ++ E W+ Sbjct: 595 EIILRKCNRILDRKGEAVPFKNKDRDDMVRTVIEPMACDGLRTICIAYRDFDDTE-PSWD 653 Query: 671 KKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWV 730 + EI +L + IED ++ VP+ I+K +A I + + Sbjct: 654 NE-------------------NEILTELTCIAVVGIEDPVRPEVPDAIAKCKQAGITVRM 694 Query: 731 LTGDKKETAENIGFACELLT--EDTTICYGEDINSLL 765 +TGD TA I C +LT +D G++ N L+ Sbjct: 695 VTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLI 731 Score = 33.9 bits (76), Expect = 1.00 Identities = 23/93 (24%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 145 LVPLLVVLGVTAIKDLVDDVARHKMDKEINN-RTCEVIKDGRFKVAKWKEIQVGDVIRLK 203 L +++V+ VTA D + + I + +I++G+ EI VGD+ ++K Sbjct: 156 LFSVIIVVLVTAFNDWSKEKQFRGLQCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVK 215 Query: 204 KNDFVPADILLLSSSEPNSLCYVETAELDGETN 236 D +PAD +L+ ++ ++ + L GE++ Sbjct: 216 YGDLLPADGILIQGND----LKIDESSLTGESD 244 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 80.9 bits (198), Expect = 7e-15 Identities = 78/334 (23%), Positives = 128/334 (38%), Gaps = 72/334 (21%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E +G I SDKTGTLT N MT + + Y + D S N +E Sbjct: 443 ETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTME----------- 491 Query: 503 GKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAA 562 LI I A ++ +G L Q + E L+ Sbjct: 492 --------LLINAIAINS-----------AYTTKILPPEKEGALPRQVGNKTECGLL--- 529 Query: 563 RNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGAD 622 GF + S++ E+ Y V FNS RK MS +++ P+ + ++Y KGA Sbjct: 530 ---GFVLDLKQDYEPVRSQMPEEKLYKVYT---FNSVRKSMSTVIKLPDESFRMYSKGAS 583 Query: 623 TVIYE------------RLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWN 670 ++ + R+ R + + ++ A + LRT+C+ Y++ +W+ Sbjct: 584 EIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWD 643 Query: 671 KKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWV 730 + +I +L + IED ++ VPE I K +A I + + Sbjct: 644 NE-------------------NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRM 684 Query: 731 LTGDKKETAENIGFACELL--TEDTTICYGEDIN 762 +TGD TA I C ++ ED G++ N Sbjct: 685 VTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFN 718 Score = 32.3 bits (72), Expect = 2.9 Identities = 40/183 (21%), Positives = 76/183 (41%), Gaps = 13/183 (7%) Query: 840 RRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAM----VVDLVKRYKKAITLAIGDGA 895 RR+ +K + ++ +D V+ R +P K ++D ++ + GDG Sbjct: 719 RRIRNEKGEIEQERIDKIWPKLRVLA-RSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGT 777 Query: 896 NDVNMIKTAHIG--VGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRY 953 ND +K A +G +GI+G + + + F + + ++ GR Y + KFL++ Sbjct: 778 NDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM-WGRNVYDSISKFLQF 836 Query: 954 FFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSL 1013 N +V F + S A + ++ L + SL L + ++ L L Sbjct: 837 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASL-----ALATEPPTETLLL 891 Query: 1014 RFP 1016 R P Sbjct: 892 RKP 894 Score = 32.0 bits (71), Expect = 3.8 Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 5/93 (5%) Query: 145 LVPLLVVLGVTAIKDLVDDVARHKMDKEINN-RTCEVIKDGRFKVAKWKEIQVGDVIRLK 203 L+ ++ V+ VTA D + + I + V++ G+ EI VGD+ ++K Sbjct: 158 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVK 217 Query: 204 KNDFVPADILLLSSSEPNSLCYVETAELDGETN 236 D +PAD L + ++ ++ + L GE++ Sbjct: 218 YGDLLPADGLFIQGND----LKIDESSLTGESD 246 >gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens] Length = 1243 Score = 80.9 bits (198), Expect = 7e-15 Identities = 78/334 (23%), Positives = 128/334 (38%), Gaps = 72/334 (21%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E +G I SDKTGTLT N MT + + Y + D S N +E Sbjct: 488 ETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTME----------- 536 Query: 503 GKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAA 562 LI I A ++ +G L Q + E L+ Sbjct: 537 --------LLINAIAINS-----------AYTTKILPPEKEGALPRQVGNKTECGLL--- 574 Query: 563 RNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGAD 622 GF + S++ E+ Y V FNS RK MS +++ P+ + ++Y KGA Sbjct: 575 ---GFVLDLKQDYEPVRSQMPEEKLYKVYT---FNSVRKSMSTVIKLPDESFRMYSKGAS 628 Query: 623 TVIYE------------RLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWN 670 ++ + R+ R + + ++ A + LRT+C+ Y++ +W+ Sbjct: 629 EIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRTICVAYRDFPSSPEPDWD 688 Query: 671 KKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWV 730 + +I +L + IED ++ VPE I K +A I + + Sbjct: 689 NE-------------------NDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRM 729 Query: 731 LTGDKKETAENIGFACELL--TEDTTICYGEDIN 762 +TGD TA I C ++ ED G++ N Sbjct: 730 VTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFN 763 Score = 32.3 bits (72), Expect = 2.9 Identities = 40/183 (21%), Positives = 76/183 (41%), Gaps = 13/183 (7%) Query: 840 RRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAM----VVDLVKRYKKAITLAIGDGA 895 RR+ +K + ++ +D V+ R +P K ++D ++ + GDG Sbjct: 764 RRIRNEKGEIEQERIDKIWPKLRVLA-RSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGT 822 Query: 896 NDVNMIKTAHIG--VGISGQEGMQAVMSSDYSFAQFRYLQRLLLVHGRWSYIRMCKFLRY 953 ND +K A +G +GI+G + + + F + + ++ GR Y + KFL++ Sbjct: 823 NDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVM-WGRNVYDSISKFLQF 881 Query: 954 FFYKNFAFTLVHFWYSFFNGYSAQTAYEDWFITLYNVLYTSLPVLLMGLLDQDVSDKLSL 1013 N +V F + S A + ++ L + SL L + ++ L L Sbjct: 882 QLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASL-----ALATEPPTETLLL 936 Query: 1014 RFP 1016 R P Sbjct: 937 RKP 939 Score = 32.0 bits (71), Expect = 3.8 Identities = 23/93 (24%), Positives = 45/93 (48%), Gaps = 5/93 (5%) Query: 145 LVPLLVVLGVTAIKDLVDDVARHKMDKEINN-RTCEVIKDGRFKVAKWKEIQVGDVIRLK 203 L+ ++ V+ VTA D + + I + V++ G+ EI VGD+ ++K Sbjct: 158 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVK 217 Query: 204 KNDFVPADILLLSSSEPNSLCYVETAELDGETN 236 D +PAD L + ++ ++ + L GE++ Sbjct: 218 YGDLLPADGLFIQGND----LKIDESSLTGESD 246 >gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] Length = 1220 Score = 75.9 bits (185), Expect = 2e-13 Identities = 76/334 (22%), Positives = 128/334 (38%), Gaps = 72/334 (21%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E +G I SDKTGTLT N MT + + Y + S ++ Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILD----------- 510 Query: 503 GKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAA 562 L+ I A ++ +G L Q + E AL+ Sbjct: 511 --------LLVHAISINS-----------AYTTKILPPEKEGALPRQVGNKTECALL--- 548 Query: 563 RNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGAD 622 GF + ++ ++ Y V FNS RK MS ++R P+G +L+ KGA Sbjct: 549 ---GFVLDLKRDFQPVREQIPEDKLYKVYT---FNSVRKSMSTVIRMPDGGFRLFSKGAS 602 Query: 623 TVIYER----------LHRMNPTKQE--TQDALDIFANETLRTLCLCYKEIEEKEFTEWN 670 ++ ++ L P ++ + ++ A + LRT+C+ Y++ + +W+ Sbjct: 603 EILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWD 662 Query: 671 KKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWV 730 + E+ DL + IED ++ VPE I K +A I + + Sbjct: 663 NE-------------------NEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRM 703 Query: 731 LTGDKKETAENIGFACELLT--EDTTICYGEDIN 762 +TGD TA I C ++ ED G++ N Sbjct: 704 VTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFN 737 Score = 32.0 bits (71), Expect = 3.8 Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 145 LVPLLVVLGVTAIKDLVDDVARHKMDKEINN-RTCEVIKDGRFKVAKWKEIQVGDVIRLK 203 L+ ++ V+ VTA D + + I + VI++G+ + VGD+ ++K Sbjct: 161 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVK 220 Query: 204 KNDFVPADILLLSSSEPNSLCYVETAELDGETN 236 D +PAD +L+ +++ ++ + L GE++ Sbjct: 221 YGDLLPADGVLIQAND----LKIDESSLTGESD 249 >gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sapiens] Length = 1173 Score = 75.9 bits (185), Expect = 2e-13 Identities = 76/334 (22%), Positives = 128/334 (38%), Gaps = 72/334 (21%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E +G I SDKTGTLT N MT + + Y + S ++ Sbjct: 462 ETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKILD----------- 510 Query: 503 GKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAA 562 L+ I A ++ +G L Q + E AL+ Sbjct: 511 --------LLVHAISINS-----------AYTTKILPPEKEGALPRQVGNKTECALL--- 548 Query: 563 RNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGAD 622 GF + ++ ++ Y V FNS RK MS ++R P+G +L+ KGA Sbjct: 549 ---GFVLDLKRDFQPVREQIPEDKLYKVYT---FNSVRKSMSTVIRMPDGGFRLFSKGAS 602 Query: 623 TVIYER----------LHRMNPTKQE--TQDALDIFANETLRTLCLCYKEIEEKEFTEWN 670 ++ ++ L P ++ + ++ A + LRT+C+ Y++ + +W+ Sbjct: 603 EILLKKCTNILNSNGELRGFRPRDRDDMVRKIIEPMACDGLRTICIAYRDFSAGQEPDWD 662 Query: 671 KKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWV 730 + E+ DL + IED ++ VPE I K +A I + + Sbjct: 663 NE-------------------NEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRM 703 Query: 731 LTGDKKETAENIGFACELLT--EDTTICYGEDIN 762 +TGD TA I C ++ ED G++ N Sbjct: 704 VTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFN 737 Score = 32.0 bits (71), Expect = 3.8 Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 145 LVPLLVVLGVTAIKDLVDDVARHKMDKEINN-RTCEVIKDGRFKVAKWKEIQVGDVIRLK 203 L+ ++ V+ VTA D + + I + VI++G+ + VGD+ ++K Sbjct: 161 LLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVK 220 Query: 204 KNDFVPADILLLSSSEPNSLCYVETAELDGETN 236 D +PAD +L+ +++ ++ + L GE++ Sbjct: 221 YGDLLPADGVLIQAND----LKIDESSLTGESD 249 >gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sapiens] Length = 1176 Score = 72.8 bits (177), Expect = 2e-12 Identities = 80/335 (23%), Positives = 129/335 (38%), Gaps = 73/335 (21%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E +G I SDKTGTLT N MT + IN + Y + N + Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILS----------- 512 Query: 503 GKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAA 562 YL+ I A ++ +G L + E AL+ Sbjct: 513 --------YLVTGISVN-----------CAYTSKILPPEKEGGLPRHVGNKTECALLGLL 553 Query: 563 RNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGAD 622 + L R + +E+ E Y V FNS RK MS +++ +G+ +++ KGA Sbjct: 554 LD-----LKRDYQDVR-NEIPEEALYKVYT---FNSVRKSMSTVLKNSDGSYRIFSKGAS 604 Query: 623 TVIYERLHRMNPTKQETQ------------DALDIFANETLRTLCLCYKEIEEKE-FTEW 669 +I ++ ++ E + ++ A+E LRT+CL +++ E EW Sbjct: 605 EIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEW 664 Query: 670 NKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIW 729 + + +I L + IED ++ VP+ I K +A I + Sbjct: 665 DNE-------------------NDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVR 705 Query: 730 VLTGDKKETAENIGFACELL--TEDTTICYGEDIN 762 ++TGD TA I C +L ED G+D N Sbjct: 706 MVTGDNINTARAIATKCGILHPGEDFLCLEGKDFN 740 Score = 32.0 bits (71), Expect = 3.8 Identities = 23/93 (24%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 145 LVPLLVVLGVTAIKDLVDDVARHKMDKEINN-RTCEVIKDGRFKVAKWKEIQVGDVIRLK 203 L+ ++ V+ VTA D + + I + VI+ G+ +I VGD+ ++K Sbjct: 160 LLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVK 219 Query: 204 KNDFVPADILLLSSSEPNSLCYVETAELDGETN 236 D +PAD +L+ ++ ++ + L GE++ Sbjct: 220 YGDLLPADGILIQGND----LKIDESSLTGESD 248 >gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sapiens] Length = 1220 Score = 72.8 bits (177), Expect = 2e-12 Identities = 80/335 (23%), Positives = 129/335 (38%), Gaps = 73/335 (21%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E +G I SDKTGTLT N MT + IN + Y + N + Sbjct: 464 ETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNILS----------- 512 Query: 503 GKLAFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAA 562 YL+ I A ++ +G L + E AL+ Sbjct: 513 --------YLVTGISVN-----------CAYTSKILPPEKEGGLPRHVGNKTECALLGLL 553 Query: 563 RNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGAD 622 + L R + +E+ E Y V FNS RK MS +++ +G+ +++ KGA Sbjct: 554 LD-----LKRDYQDVR-NEIPEEALYKVYT---FNSVRKSMSTVLKNSDGSYRIFSKGAS 604 Query: 623 TVIYERLHRMNPTKQETQ------------DALDIFANETLRTLCLCYKEIEEKE-FTEW 669 +I ++ ++ E + ++ A+E LRT+CL +++ E EW Sbjct: 605 EIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASEGLRTICLAFRDFPAGEPEPEW 664 Query: 670 NKKFMAASVASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIW 729 + + +I L + IED ++ VP+ I K +A I + Sbjct: 665 DNE-------------------NDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGITVR 705 Query: 730 VLTGDKKETAENIGFACELL--TEDTTICYGEDIN 762 ++TGD TA I C +L ED G+D N Sbjct: 706 MVTGDNINTARAIATKCGILHPGEDFLCLEGKDFN 740 Score = 32.0 bits (71), Expect = 3.8 Identities = 23/93 (24%), Positives = 46/93 (49%), Gaps = 5/93 (5%) Query: 145 LVPLLVVLGVTAIKDLVDDVARHKMDKEINN-RTCEVIKDGRFKVAKWKEIQVGDVIRLK 203 L+ ++ V+ VTA D + + I + VI+ G+ +I VGD+ ++K Sbjct: 160 LLSVVCVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVK 219 Query: 204 KNDFVPADILLLSSSEPNSLCYVETAELDGETN 236 D +PAD +L+ ++ ++ + L GE++ Sbjct: 220 YGDLLPADGILIQGND----LKIDESSLTGESD 248 >gi|66932949 ATPase type 13A4 [Homo sapiens] Length = 1196 Score = 65.5 bits (158), Expect = 3e-10 Identities = 97/475 (20%), Positives = 186/475 (39%), Gaps = 81/475 (17%) Query: 446 GQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYADGKL 505 GQ++ + DKTGTLT++ + + G + D R+ Q H+ W Sbjct: 478 GQLNLVCFDKTGTLTRDGLD-----LWGVVSCD-RNGFQEVHSFASGQALPWGPLCAAMA 531 Query: 506 AFYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAARNF 565 + + L++ G +++ F + T ++ A S D+ + + Sbjct: 532 SCHSLILLDGTIQGDPLDLKMF------------EATTWEM---AFSGDDFHIKGVPAHA 576 Query: 566 GFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSIIVRTPEGNIKLYCKGADTVI 625 RT + + + + +L F+S +RM++IV+ G+ + KGA + Sbjct: 577 MVVKPCRTASQVPVEGIA------ILHQFPFSSALQRMTVIVQEMGGDRLAFMKGAPERV 630 Query: 626 YERLHRMN-PTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRD 684 PT ++ L I+ + R + L YK++E N Sbjct: 631 ASFCQPETVPTSFVSE--LQIYTTQGFRVIALAYKKLE-------------------NDH 669 Query: 685 EALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGF 744 A E +E DLI LG +E++L++ + +L A I+ ++TGD +TA + Sbjct: 670 HATTLTRETVESDLIFLGLLILENRLKEETKPVLEELISARIRTVMITGDNLQTAITVAR 729 Query: 745 ACELLTEDTTICYGEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGS 804 +++E + +E G A + + E + I+ G+ Sbjct: 730 KSGMVSESQKVIL-----------IEANETTGSSSASISWTLVE-------EKKHIMYGN 771 Query: 805 WLNEI-LLEKKTKRNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAV 863 N I + ++ + + + F T + + +Q L K + Sbjct: 772 QDNYINIRDEVSDKGREGSYHFALTGKSFHVISQHFSSLLPK------------ILINGT 819 Query: 864 ICCRVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQA 918 I R++P QK+ +V+ ++ + + GDGAND +K AH+G+ +S QE A Sbjct: 820 IFARMSPGQKSSLVEEFQKLDYFVGMC-GDGANDCGALKMAHVGISLSEQEASVA 873 >gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] Length = 1020 Score = 59.7 bits (143), Expect = 2e-08 Identities = 167/760 (21%), Positives = 274/760 (36%), Gaps = 216/760 (28%) Query: 180 VIKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGETNLKF 239 VI++G +E+ VGD++ +K D VPAD+ ++SS C V+ + L GE+ Sbjct: 169 VIREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHG----CKVDNSSLTGES---- 220 Query: 240 KMSLEITDQYLQREDTLATFDGFIECEEPNNRLDKFT--GTLFWRNTSFPLDADKILLRG 297 EP R +FT L RN F Sbjct: 221 ---------------------------EPQTRSPEFTHENPLETRNICF-------FSTN 246 Query: 298 CVIRNTDFCHGLVIFAGADT---KIMKNSGKTRFKRTKIDYLMNYMVYTIFVVLILLSAG 354 CV G+VI G T +I + RT I + + + I V + L Sbjct: 247 CV---EGTARGIVIATGDRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVS 303 Query: 355 -----LAIGHAYWEAQVGNSSWYLYDGEDDTPSYRGFLIFWGYIIVLNT----MVPISLY 405 L +G+++ EA +IF IIV N + +++ Sbjct: 304 FFVLSLILGYSWLEA----------------------VIFLIGIIVANVPEGLLATVTVC 341 Query: 406 VSVEVIRLGQSHFINWDLQMYYAEKDTPAKARTTTLNEQLGQIHYIFSDKTGTLTQNIMT 465 +++ R+ + + + +L+ E LG I SDKTGTLTQN MT Sbjct: 342 LTLTAKRMARKNCLVKNLEAV----------------ETLGSTSTICSDKTGTLTQNRMT 385 Query: 466 FKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYADGKLAFYDHYLIEQIQSGKEPEVR 525 + QI+ +T D A +D + P Sbjct: 386 VAHMWFDNQIH-------------------EADTTEDQSGATFDK---------RSPTWT 417 Query: 526 QFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVNAARNFGFAFLARTQNTITISELGTE 585 + +C+ + GQ N + D + + A L + + + Sbjct: 418 ALSRIAGLCNRAVFKA--GQENISVSKRDTAGDASES-----ALLKCIELSCGSVRKMRD 470 Query: 586 RTYNVLAILDFNSDRK-RMSIIVR--TPEGNIKLYCKGADTVIYERLHRMN------PTK 636 R V A + FNS K ++SI R +P+ ++ L KGA I +R + P Sbjct: 471 RNPKV-AEIPFNSTNKYQLSIHEREDSPQSHV-LVMKGAPERILDRCSTILVQGKEIPLD 528 Query: 637 QETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEK 696 +E QDA F N + L + + + + KF T D++ EK Sbjct: 529 KEMQDA---FQNAYMELGGLGERVLGFCQLNLPSGKFPRGFKFDT------DELNFPTEK 579 Query: 697 DLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACELLTEDTTIC 756 L +G ++ D + VP+ + K A IK+ ++TGD TA+ I +++E Sbjct: 580 -LCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETV 638 Query: 757 YGEDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTK 816 EDI + L+ M R +A ++ GS L ++ E+ Sbjct: 639 --EDIAARLNIPMSQVNPREA-------------------KACVVHGSDLKDMTSEQL-- 675 Query: 817 RNKILKLKFPRTEEERRMRTQSKRRLEAKKEQRQKNFVDLACECSAVICCRVTPKQKAMV 876 ++ILK + ++ R +P+QK ++ Sbjct: 676 -DEILK------------------------------------NHTEIVFARTSPQQKLII 698 Query: 877 VDLVKRYKKAITLAIGDGANDVNMIKTAHIGV--GISGQE 914 V+ +R + AI GDG ND +K A IG+ GISG + Sbjct: 699 VEGCQR-QGAIVAVTGDGVNDSPALKKADIGIAMGISGSD 737 >gi|148839292 ATPase type 13A3 [Homo sapiens] Length = 1226 Score = 59.7 bits (143), Expect = 2e-08 Identities = 77/347 (22%), Positives = 139/347 (40%), Gaps = 60/347 (17%) Query: 581 ELGTERTYNVLAILDFNSDRKRMSIIVRT-PEGNIKLYCKGADTVIYERLHRMNPTKQET 639 EL ++ F+S +RMS++ R + + Y KGA I L + + Sbjct: 613 ELPATYEIGIVRQFPFSSALQRMSVVARVLGDRKMDAYMKGAPEAI-AGLCKPETVPVDF 671 Query: 640 QDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAASVASTNRDEALDKVYEEIEKDLI 699 Q+ L+ F + R + L ++++E K W+K V + +RD IE ++ Sbjct: 672 QNVLEDFTKQGFRVIALAHRKLESK--LTWHK------VQNISRDA--------IENNMD 715 Query: 700 LLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKETAENIGFACEL-LTEDTTICYG 758 +G +++KL+ P + L KA+I+ ++TGD TA ++ C + L +D I Sbjct: 716 FMGLIIMQNKLKQETPAVLEDLHKANIRTVMVTGDSMLTAVSVARDCGMILPQDKVI--- 772 Query: 759 EDINSLLHARMENQRNRGGVYAKFAPPVQESFFPPGGNRALIITGSWLNEILLEKKTKRN 818 + E+ P G A I +W L + + + Sbjct: 773 ---------------------------IAEALPPKDGKVAKI---NWHYADSLTQCSHPS 802 Query: 819 KI----LKLKFPRTEEERRMRTQSKRRLEAKK-EQRQKNFVDLACECS--AVICCRVTPK 871 I + +K E T+ + K ++F DL + + R+ P Sbjct: 803 AIDPEAIPVKLVHDSLEDLQMTRYHFAMNGKSFSVILEHFQDLVPKLMLHGTVFARMAPD 862 Query: 872 QKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEGMQA 918 QK +++ ++ + + GDGAND +K AH G+ +S E A Sbjct: 863 QKTQLIEALQNVDYFVGMC-GDGANDCGALKRAHGGISLSELEASVA 908 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 55.5 bits (132), Expect = 3e-07 Identities = 75/327 (22%), Positives = 132/327 (40%), Gaps = 68/327 (20%) Query: 443 EQLGQIHYIFSDKTGTLTQNIMTFKKCCINGQIYGDHRDASQHNHNKIEQVDFSWNTYAD 502 E LG + I SDKTGTLT+N MT + G H + + +N+ +V D Sbjct: 339 ETLGCCNVICSDKTGTLTKNEMTVTHIFTSD---GLHAEVTGVGYNQFGEV------IVD 389 Query: 503 GKLA--FYDHYLIEQIQSGKEPEVRQFFFLLAVCHTVMVDRTDGQLNYQAASPDEGALVN 560 G + FY+ + +++G VC+ ++ N P EGAL+ Sbjct: 390 GDVVHGFYNPAVSRIVEAG------------CVCNDAVIRN-----NTLMGKPTEGALIA 432 Query: 561 AARNFGFAFLARTQNTITISELGTERTYNVLAILDFNSDRKRMSI--IVRTPEGNIKL-Y 617 A G G ++ Y A F+S++K M++ + RT + ++ + Sbjct: 433 LAMKMGLD--------------GLQQDYIRKAEYPFSSEQKWMAVKCVHRTQQDRPEICF 478 Query: 618 CKGADTVIYERLHRMNPTKQETQDALDIFANETLRTLCLCYKEIEEKEFTEWNKKFMAAS 677 KGA YE++ + T Q L TL +++ ++E + Sbjct: 479 MKGA----YEQVIKYCTTYQSKGQTL---------TLTQQQRDVYQQEKARMGSAGLRVL 525 Query: 678 VASTNRDEALDKVYEEIEKDLILLGATAIEDKLQDGVPETISKLAKADIKIWVLTGDKKE 737 ++ + L LG I D + GV E ++ L + + I ++TGD +E Sbjct: 526 ALASGPELG----------QLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQE 575 Query: 738 TAENIGFACELLTEDTTICYGEDINSL 764 TA I L ++ + GE+I+++ Sbjct: 576 TAVAIASRLGLYSKTSQSVSGEEIDAM 602 Score = 35.4 bits (80), Expect = 0.34 Identities = 27/121 (22%), Positives = 58/121 (47%), Gaps = 6/121 (4%) Query: 115 QFKRAANLYFLALLILQAVPQISTLAWYTTLVPLLVVLGVTAIKDLVDDVARHKMDKEIN 174 QFK + LA ++ + A T V +L+V+ V +++ + + ++ K + Sbjct: 78 QFKNPLIMLLLASAVISVLMHQFDDAVSIT-VAILIVVTVAFVQEYRSEKSLEELSKLVP 136 Query: 175 NRTCEVIKDGRFKVAKWKEIQVGDVIRLKKNDFVPADILLLSSSEPNSLCYVETAELDGE 234 C +++G+ + +++ GD + L D VPAD+ L + + + ++ + L GE Sbjct: 137 PE-CHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLS----IDESSLTGE 191 Query: 235 T 235 T Sbjct: 192 T 192 Score = 31.2 bits (69), Expect = 6.5 Identities = 16/49 (32%), Positives = 27/49 (55%), Gaps = 2/49 (4%) Query: 867 RVTPKQKAMVVDLVKRYKKAITLAIGDGANDVNMIKTAHIGVGISGQEG 915 R +P+ K ++ +++ + + GDG ND +K A IGV + GQ G Sbjct: 619 RASPRHKMKIIKSLQKNGSVVAMT-GDGVNDAVALKAADIGVAM-GQTG 665 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.137 0.409 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,598,347 Number of Sequences: 37866 Number of extensions: 1867741 Number of successful extensions: 7182 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 64 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 6697 Number of HSP's gapped (non-prelim): 358 length of query: 1251 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1137 effective length of database: 13,930,794 effective search space: 15839312778 effective search space used: 15839312778 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.