BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|5031579 A-kinase anchor protein 8 [Homo sapiens] (692 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|5031579 A-kinase anchor protein 8 [Homo sapiens] 1426 0.0 gi|49472841 A kinase (PRKA) anchor protein 8-like [Homo sapiens] 299 7e-81 gi|33946297 zinc finger protein 326 isoform 1 [Homo sapiens] 176 8e-44 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 47 5e-05 gi|71061468 centromere protein E [Homo sapiens] 45 3e-04 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 44 4e-04 gi|30795231 brain abundant, membrane attached signal protein 1 [... 44 5e-04 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 44 5e-04 gi|46409304 glutamate-rich 1 [Homo sapiens] 44 7e-04 gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 43 9e-04 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 43 0.001 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 43 0.001 gi|84872173 zinc finger protein 131 [Homo sapiens] 43 0.001 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 42 0.001 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 42 0.002 gi|56606114 trichohyalin-like 1 [Homo sapiens] 42 0.002 gi|21735569 claspin [Homo sapiens] 42 0.002 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 42 0.002 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 42 0.002 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 42 0.002 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 41 0.004 gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sa... 40 0.006 gi|209915570 amyloid beta A4 protein isoform e precursor [Homo s... 40 0.006 gi|153070260 myristoylated alanine-rich protein kinase C substra... 40 0.006 gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 40 0.006 gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] 40 0.007 gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 40 0.009 gi|239746922 PREDICTED: similar to cancer/testis antigen family ... 39 0.012 gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] 39 0.012 gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] 39 0.012 >gi|5031579 A-kinase anchor protein 8 [Homo sapiens] Length = 692 Score = 1426 bits (3691), Expect = 0.0 Identities = 692/692 (100%), Positives = 692/692 (100%) Query: 1 MDQGYGGYGAWSAGPANTQGAYGTGVASWQGYENYNYYGAQNTSVTTGATYSYGPASWEA 60 MDQGYGGYGAWSAGPANTQGAYGTGVASWQGYENYNYYGAQNTSVTTGATYSYGPASWEA Sbjct: 1 MDQGYGGYGAWSAGPANTQGAYGTGVASWQGYENYNYYGAQNTSVTTGATYSYGPASWEA 60 Query: 61 AKANDGGLAAGAPAMHMASYGPEPCTDNSDSLIAKINQRLDMMSKEGGRGGSGGGGEGIQ 120 AKANDGGLAAGAPAMHMASYGPEPCTDNSDSLIAKINQRLDMMSKEGGRGGSGGGGEGIQ Sbjct: 61 AKANDGGLAAGAPAMHMASYGPEPCTDNSDSLIAKINQRLDMMSKEGGRGGSGGGGEGIQ 120 Query: 121 DRESSFRFQPFESYDSRPCLPEHNPYRPSYSYDYEFDLGSDRNGSFGGQYSECRDPARER 180 DRESSFRFQPFESYDSRPCLPEHNPYRPSYSYDYEFDLGSDRNGSFGGQYSECRDPARER Sbjct: 121 DRESSFRFQPFESYDSRPCLPEHNPYRPSYSYDYEFDLGSDRNGSFGGQYSECRDPARER 180 Query: 181 GSLDGFMRGRGQGRFQDRSNPGTFMRSDPFVPPAASSEPLSTPWNELNYVGGRGLGGPSP 240 GSLDGFMRGRGQGRFQDRSNPGTFMRSDPFVPPAASSEPLSTPWNELNYVGGRGLGGPSP Sbjct: 181 GSLDGFMRGRGQGRFQDRSNPGTFMRSDPFVPPAASSEPLSTPWNELNYVGGRGLGGPSP 240 Query: 241 SRPPPSLFSQSMAPDYGVMGMQGAGGYDSTMPYGCGRSQPRMRDRDRPKRRGFDRFGPDG 300 SRPPPSLFSQSMAPDYGVMGMQGAGGYDSTMPYGCGRSQPRMRDRDRPKRRGFDRFGPDG Sbjct: 241 SRPPPSLFSQSMAPDYGVMGMQGAGGYDSTMPYGCGRSQPRMRDRDRPKRRGFDRFGPDG 300 Query: 301 TGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEK 360 TGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEK Sbjct: 301 TGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEK 360 Query: 361 EDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRF 420 EDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRF Sbjct: 361 EDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRF 420 Query: 421 ISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKETAKPKPDPFKGIGQEHFFKKIEAAH 480 ISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKETAKPKPDPFKGIGQEHFFKKIEAAH Sbjct: 421 ISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKETAKPKPDPFKGIGQEHFFKKIEAAH 480 Query: 481 CLACDMLIPAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEKYL 540 CLACDMLIPAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEKYL Sbjct: 481 CLACDMLIPAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEKYL 540 Query: 541 KGEDPFTSETVDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESS 600 KGEDPFTSETVDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESS Sbjct: 541 KGEDPFTSETVDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESS 600 Query: 601 GEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEA 660 GEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEA Sbjct: 601 GEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEA 660 Query: 661 ESAQTRVAPAPAAADAEVEQTDAESKDAVPTE 692 ESAQTRVAPAPAAADAEVEQTDAESKDAVPTE Sbjct: 661 ESAQTRVAPAPAAADAEVEQTDAESKDAVPTE 692 >gi|49472841 A kinase (PRKA) anchor protein 8-like [Homo sapiens] Length = 646 Score = 299 bits (765), Expect = 7e-81 Identities = 238/693 (34%), Positives = 341/693 (49%), Gaps = 126/693 (18%) Query: 7 GYGAWSAGPANTQGAYGTGVASWQGYENYNY---YGAQNTSVTTGATYSYGPA---SWEA 60 GYG W++G +GYE Y Y YG NT+ Y YG A SWE Sbjct: 30 GYGTWNSGTN-------------RGYEGYGYGYGYGQDNTT-----NYGYGMATSHSWEM 71 Query: 61 AKANDGGLAAGAPAMHMASYGPEPCTDNSDSLIAKINQRLDMMSK------EGGRGGSGG 114 ++ A A AS +DS++++INQRLDM+ +GG GSGG Sbjct: 72 PSSDTN---ANTSASGSAS---------ADSVLSRINQRLDMVPHLETDMMQGGVYGSGG 119 Query: 115 GGEGIQDRESSFRFQPFESYDSRPCLPEHNPYRPSYSYDYEFDLGSDRNGSFGGQYSECR 174 R+ +ES DSR L E + YR Y Y +L + ++ GQY R Sbjct: 120 E-----------RYDSYESCDSRAVLSERDLYRSGYDYS---ELDPEMEMAYEGQYDAYR 165 Query: 175 DPARERGSLDGFMRGRGQGRFQDRSNPGTFMRSDPFVPPAASSEPLSTPWNEL--NYVGG 232 D R RG+ D F R QG +D A S P+++ + + + +G Sbjct: 166 DQFRMRGN-DTF-GPRAQGWARD----------------ARSGRPMASGYGRMWEDPMGA 207 Query: 233 RGLGGPSPSRPPPSLFSQSMAPDYGVM-GMQGAGGYD--STMPYGCGRSQPRMRDRDRPK 289 RG SR P SLFSQ++ P+YG+ GM+G G + S +G G +MR + Sbjct: 208 RGQCMSGASRLP-SLFSQNIIPEYGMFQGMRGGGAFPGGSRFGFGFGNGMKQMRRTWKTW 266 Query: 290 RRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVD-SEGDFSENDDAA-GDFRSGDE----- 342 R +KRKQ +EPD+K R D S+ S+ND+ G+ G E Sbjct: 267 TTADFRTKK----KKRKQGGSPDEPDSKATRTDCSDNSDSDNDEGTEGEATEGLEGTEAV 322 Query: 343 ----EFKGEDELC-DSGRQRGEKEDE-------DEDVKKRREKQ-------RRRDRTRDR 383 GEDE + GR+ G+++ E DE+ + +R+ Q +++ R RDR Sbjct: 323 EKGSRVDGEDEEGKEDGREEGKEDPEKGALTTQDENGQTKRKLQAGKKSQDKQKKRQRDR 382 Query: 384 AADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKK 443 +RIQF CS+CK+R+F ++E+ HL SKFHKE +++ TKLP +T +FLQEY+ N+ KK Sbjct: 383 MVERIQFVCSLCKYRTFYEDEMASHLDSKFHKEHFKYVGTKLPKQTADFLQEYVTNKTKK 442 Query: 444 IEKRRQELMEKETAKPK----PDPFKGIGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHL 499 E+ R+ + + + + D + I EHF KK+EAAHC ACD+ IP Q ++Q+HL Sbjct: 443 TEELRKTVEDLDGLIHQIYRDQDLTQEIAMEHFVKKVEAAHCAACDLFIPMQFGIIQKHL 502 Query: 500 HSVDHNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEKYLKGEDPFTSETVDPEMEGDD 559 ++DHN NRRL EQ KK+SL VA+S+LNN+ I K LE+YLKGE+PFT ++ + E E ++ Sbjct: 503 KTMDHNRNRRLMMEQSKKSSLMVARSILNNKLISKKLERYLKGENPFT-DSPEEEKEQEE 561 Query: 560 NLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEGPTDTAEAGSDP 619 GG + E A A V E AP S P P + E G+ P Sbjct: 562 AEGGALDEGAQGEAAGISEGAEGVPAQPPVPPEPAPGAVSPPPPP----PPEEEEEGAVP 617 Query: 620 QAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNG 652 L+ Q+ +G+P E E G G Sbjct: 618 LLGGALQRQI-------RGIPGLDVEDDEEGGG 643 >gi|33946297 zinc finger protein 326 isoform 1 [Homo sapiens] Length = 582 Score = 176 bits (445), Expect = 8e-44 Identities = 184/633 (29%), Positives = 270/633 (42%), Gaps = 110/633 (17%) Query: 33 ENYNYYGAQNT-SVTTGATYSYGPASWEAAKANDGGLAAGAPAMHMASYGPEPCTDNSDS 91 ++Y + +NT G YGP S+ + G SYG + D+ Sbjct: 5 DDYTHSACRNTYQGFNGMDRDYGPGSYGGMDRDYGH----------GSYGGQRSMDSY-- 52 Query: 92 LIAKINQRLDMMSKEGGRGGSGGGGEGIQDRESSFRFQPFESYDSRPCLPEHNPYRPSYS 151 +NQ M + GG GGS RF P+ESYDSR L + YR Y Sbjct: 53 ----LNQSYGMDNHSGGGGGS--------------RFGPYESYDSRSSLGGRDLYRSGYG 94 Query: 152 YDYEFDLGSDRNGSFGGQYSECRDPARERGSLDGFMRGRGQGRFQ-----DRSNPGTFMR 206 ++ S GS+GG++ + R SLD F GR QG RS Sbjct: 95 FNEPEQ--SRFGGSYGGRFE-----SSYRNSLDSF-GGRNQGGSSWEAPYSRSKLRPGFM 146 Query: 207 SDPFVPPAASSEPLSTPWNELNYVGGRGLGGPSPSRPPPSLFSQSMAPDYGVMGMQGAGG 266 D +S S+P + VG RG G P+ P S F G GG Sbjct: 147 EDRGRENYSSYSSFSSPHMKPAPVGSRGRGTPAY---PESTF--------GSRNYDAFGG 195 Query: 267 YDSTMPYGCGRSQPRMRDRDRPKRRG----FDRFGPDGT-----GRKRKQFQLYEEPDTK 317 + G GR + M D R G + + T G KRK Q + +P Sbjct: 196 PST----GRGRGRGHMGDFGSIHRPGIVVDYQNKSTNVTVAAARGIKRKMMQPFNKPS-- 249 Query: 318 LARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDED--VKKRREKQR 375 G F + A + L S + K +E+E ++ RREKQR Sbjct: 250 -------GTFIKKPKLAKPME--------KISLSKSPTKTDPKNEEEEKRRIEARREKQR 294 Query: 376 RR-DRTRDRAAD--RIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRFIS--TKLPDKTV 430 RR ++ ++ D R+ F CS CKFR+F++++I+ HL+S H+ETL I TK + Sbjct: 295 RRREKNSEKYGDGYRMAFTCSFCKFRTFEEKDIELHLESSSHQETLDHIQKQTKFDKVVM 354 Query: 431 EFLQEYIVNRNKKIEKRRQELMEK-ETAKP-KPDPFKGIGQEHFFKKIEAAHCLACDMLI 488 EFL E +VN+ KK R+Q+ + E K + D +G+ + K+E HC AC + I Sbjct: 355 EFLHECMVNKFKKTSIRKQQTNNQTEVVKIIEKDVMEGVTVDDHMMKVETVHCSACSVYI 414 Query: 489 PAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEKYLKGEDPF-- 546 PA +Q+HL S DH ++ EQ K+ S+ A S+LNN + E+++KGE+PF Sbjct: 415 PALHSSVQQHLKSPDHIKGKQAYKEQIKRESVLTATSILNNPIVKARYERFVKGENPFEI 474 Query: 547 TSETVDPEMEGD-----------DNLGGEDKKETPEEVA-ADVLAEVITAAVRAVDGEGA 594 + D ++EGD + ED++E EEV + + EV ++GEG Sbjct: 475 QDHSQDQQIEGDEEDEEKIDEPIEEEEDEDEEEEAEEVGEVEEVEEVEEVREGGIEGEG- 533 Query: 595 PAPESSGEPAEDEGPTDTAEAGSDPQAEQLLEE 627 + GE E + G + E+L EE Sbjct: 534 -NIQGVGEGGEVGVVGEVEGVGEVEEVEELEEE 565 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 47.4 bits (111), Expect = 5e-05 Identities = 88/417 (21%), Positives = 171/417 (41%), Gaps = 65/417 (15%) Query: 281 RMRDRDRPKRRGFDRFGPDGTGRK----RKQFQLYEEPDTKLARVDSE-GDFSENDDAAG 335 + RD ++ K R TG+K +K+ Q E +T ++V + G +++ A Sbjct: 241 KKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAE 300 Query: 336 DFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVC 395 + +++ +G+ + D +++GEKE+++++ KK K +Q A + Sbjct: 301 TPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSK---------ATVKAMQEALAKL 351 Query: 396 KFRSFDDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKE 455 K ++EE QK + + K R + K E L++ R K+ EK R+E ++KE Sbjct: 352 K----EEEERQKREEEERIK---RLEELEAKRKEEERLEQEKRERKKQKEKERKERLKKE 404 Query: 456 -TAKPKPDPFKGIGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHLHSVDHNHNRRLAAEQ 514 K E K ++A + +P++ L ++ + + R+ +Q Sbjct: 405 GKLLTKSQREARARAEATLKLLQAQ-----GVEVPSKDSLPKK--RPIYEDKKRKKIPQQ 457 Query: 515 FKKTSLHVAKSVLNNRHIVKMLEKYLKG--EDPFTSETVDPEMEGDDNLGGEDKKETPEE 572 + +K V + + +E +G E T V+PE E D G D E Sbjct: 458 LE------SKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEA--- 508 Query: 573 VAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCG 632 +A+D E + ++ + P E E E+E D ++E+ EE+ Sbjct: 509 MASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEE----------DEESEEEEEEE---- 554 Query: 633 TAHEKGVPKARSEAAEAGNGAETMAAEAESAQT--RVAPAPAAADAEVEQTDAESKD 687 SE +E E ++ E +S +T + ++D+E + D +K+ Sbjct: 555 ---------GESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKE 602 Score = 30.4 bits (67), Expect = 5.7 Identities = 19/81 (23%), Positives = 37/81 (45%), Gaps = 3/81 (3%) Query: 312 EEPDTKLARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGR---QRGEKEDEDEDVK 368 EE + + D E + E ++ + GDEE + + DSG+ ++ KE + Sbjct: 534 EEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEY 593 Query: 369 KRREKQRRRDRTRDRAADRIQ 389 + + + +R D+A RI+ Sbjct: 594 DSDDDRTKEERAYDKAKRRIE 614 >gi|71061468 centromere protein E [Homo sapiens] Length = 2701 Score = 44.7 bits (104), Expect = 3e-04 Identities = 35/118 (29%), Positives = 62/118 (52%), Gaps = 10/118 (8%) Query: 345 KGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEE 404 K E E + ++ E +E + V K R+ RR + T D+++ + K R D E Sbjct: 1865 KLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKAR---DLE 1921 Query: 405 IQKHLQ-----SKFHKETLRFISTKLPDKTVEF--LQEYIVNRNKKIEKRRQELMEKE 455 IQ+ L+ SK HKET+ + K+ +KT++ +Q+ + +++K+ QEL +KE Sbjct: 1922 IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKE 1979 Score = 38.5 bits (88), Expect = 0.021 Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 12/142 (8%) Query: 326 DFSENDDAAGDFRSGDEEFKGED--------ELCDSGRQRGEKEDEDEDVKKRREKQRRR 377 + E D+ S E+FK +D E+ ++ E DE + V K ++ +R Sbjct: 1391 NMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRL 1450 Query: 378 DRTRDRAADRIQFACSVCKFRSFDDEEIQK--HLQSKFHKETLRFISTKLPDKTVEF--L 433 +D+++ + + EE K H K +ET+ + L +K E + Sbjct: 1451 QEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEISTI 1510 Query: 434 QEYIVNRNKKIEKRRQELMEKE 455 Q+ + N K++ + QE+ EKE Sbjct: 1511 QKQLEAINDKLQNKIQEIYEKE 1532 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 44.3 bits (103), Expect = 4e-04 Identities = 39/179 (21%), Positives = 73/179 (40%), Gaps = 16/179 (8%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R R DR R +RR DR R+R++ + E D + + N + Sbjct: 69 RQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERE 128 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCK 396 + E +G D D R+R + D +++ +++ +++R+R R+R +R Sbjct: 129 RETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKER--------- 179 Query: 397 FRSFDDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKE 455 E +K+ Q + +E R K D+ E +E R + E R+ ++E Sbjct: 180 -------EREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRE 231 Score = 43.5 bits (101), Expect = 7e-04 Identities = 39/184 (21%), Positives = 82/184 (44%), Gaps = 17/184 (9%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R + R RD ++ + R DR T R R++ + E + R + E Sbjct: 147 RERERQRDAEKERERQTDRERQRQTERNRQKER--EREKNRQERRERE------------ 192 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCK 396 R ++E K ED + GR+R + + + + +++R+ R RDR R +R + A + Sbjct: 193 -RQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQA--ERE 249 Query: 397 FRSFDDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKET 456 S + E K + + ++ R K ++ + ++ R+++ E++R+ E+E Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309 Query: 457 AKPK 460 + + Sbjct: 310 ERER 313 Score = 40.4 bits (93), Expect = 0.006 Identities = 31/114 (27%), Positives = 54/114 (47%), Gaps = 3/114 (2%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R + R R+R+R ++R +R R+R+ + E+ + + +E D N + Sbjct: 303 RQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGRE 362 Query: 337 FRSGDEEFKGEDELCD--SGRQRGEKE-DEDEDVKKRREKQRRRDRTRDRAADR 387 R E + + D S R+R E+E D D D +K RE+Q +DR R ++ Sbjct: 363 GRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEK 416 Score = 39.7 bits (91), Expect = 0.009 Identities = 28/107 (26%), Positives = 48/107 (44%), Gaps = 13/107 (12%) Query: 281 RMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSG 340 R DR+R ++R T R+R++ E + D E + + D R Sbjct: 226 RQTDRERDRQRK--------TEREREKQAERERASERETERDKERERERDRD-----RDR 272 Query: 341 DEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADR 387 D K + D RQR + D + + K+ R+++R R+R R+R +R Sbjct: 273 DRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER 319 Score = 39.7 bits (91), Expect = 0.009 Identities = 32/119 (26%), Positives = 56/119 (47%), Gaps = 9/119 (7%) Query: 277 RSQPRMRDRDRPKRRGFDR-----FGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSEND 331 R + + R+R R ++ DR G +G + ++ + E D + AR E + + Sbjct: 335 RDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDR 394 Query: 332 DAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKR---REKQRRRDRTRDRAADR 387 D + E+ + + R+R EK+ E E ++R REKQ+ R+R R+R DR Sbjct: 395 DRQKERERQTEKDRDGQRETEKQRER-EKDRESERGRERGREREKQKGRERDRERQTDR 452 Score = 37.7 bits (86), Expect = 0.036 Identities = 31/114 (27%), Positives = 55/114 (48%), Gaps = 3/114 (2%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRK-QFQLYEEPDTKLARVDSEGDFSEND-DAA 334 R + R R+R+R ++R +R RKRK Q ++ E + + R E + + Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376 Query: 335 GDFRSGDE-EFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADR 387 D +S E E + D D ++R + ++D D ++ EKQR R++ R+ R Sbjct: 377 RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430 Score = 34.7 bits (78), Expect = 0.30 Identities = 28/111 (25%), Positives = 50/111 (45%), Gaps = 1/111 (0%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R + RDR+ ++R R R RK+ + E + + ++E D E + Sbjct: 287 RQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD-REKERERKR 345 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADR 387 R + + + + GR++ E+E E E + R+ + R +R RDR DR Sbjct: 346 KRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDR 396 Score = 33.9 bits (76), Expect = 0.52 Identities = 29/111 (26%), Positives = 46/111 (41%), Gaps = 25/111 (22%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R+ R +RD+ + R DR R R+Q + + D K R Sbjct: 250 RASERETERDKERERERDR----DRDRDRRQKERERQTDRKRQRRTE------------- 292 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADR 387 R + E K E RQR + + + + K+ RE++R R+R R R +R Sbjct: 293 -RDRETERKRE-------RQRERERERERNRKRERERERERERERQRETER 335 Score = 32.7 bits (73), Expect = 1.2 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 2/69 (2%) Query: 319 ARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRD 378 A D++GD E + R E + + D R+R ++D + RE+QR R+ Sbjct: 45 AHKDADGDDRERNRQKE--RERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDRE 102 Query: 379 RTRDRAADR 387 + R+R DR Sbjct: 103 KERERQTDR 111 Score = 30.0 bits (66), Expect = 7.5 Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 4/45 (8%) Query: 276 GRSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLAR 320 GR + + + R+R + R DR GR+RK+ LY P + AR Sbjct: 433 GREREKQKGRERDRERQTDR----QAGRQRKRSTLYVNPPPRTAR 473 >gi|30795231 brain abundant, membrane attached signal protein 1 [Homo sapiens] Length = 227 Score = 43.9 bits (102), Expect = 5e-04 Identities = 37/131 (28%), Positives = 55/131 (41%), Gaps = 11/131 (8%) Query: 565 DKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEGPTDTAEAGSD-PQAEQ 623 +++ TP+E AE A +G+ P ++ G+ E EG D A A + P+AE Sbjct: 32 EEEGTPKESEPQAAAE----PAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEP 87 Query: 624 LLEEQVPCGTAHEKGVPKARSEA------AEAGNGAETMAAEAESAQTRVAPAPAAADAE 677 E A P+ A EA AE AA AESA P+ + E Sbjct: 88 EKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEEGE 147 Query: 678 VEQTDAESKDA 688 ++T+A + A Sbjct: 148 PKKTEAPAAPA 158 Score = 39.7 bits (91), Expect = 0.009 Identities = 41/144 (28%), Positives = 61/144 (42%), Gaps = 11/144 (7%) Query: 552 DPEM-EGDDNLGGEDKKETPEEVAADVLA---EVITAAVRAVDGEGAPAPESSGEPAEDE 607 +PE EG E K +E AA A E AA A + AP + EP+++E Sbjct: 86 EPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEE 145 Query: 608 GPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEAESAQTRV 667 G EA + P A++ + P + SEAA + ET AA + T Sbjct: 146 GEPKKTEAPAAPAAQETKSDGAPASDS-----KPGSSEAAPSSK--ETPAATEAPSSTPK 198 Query: 668 APAPAAADAEVEQTDAESKDAVPT 691 A PAA+ E + +A + ++ T Sbjct: 199 AQGPAASAEEPKPVEAPAANSDQT 222 Score = 37.0 bits (84), Expect = 0.061 Identities = 36/127 (28%), Positives = 49/127 (38%), Gaps = 26/127 (20%) Query: 588 AVDGEGAPA---PESSGEPA------------------EDEGPTDTAEAGSD-PQAEQLL 625 A + EG P P+++ EPA E EG D A A + P+AE Sbjct: 30 ATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEK 89 Query: 626 EEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEAESAQTRVAPAPAAADAEVEQTDAES 685 E G A K P E +A G ++A+ APA +AA A E+ E Sbjct: 90 TE----GAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEPSKEE 145 Query: 686 KDAVPTE 692 + TE Sbjct: 146 GEPKKTE 152 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 43.9 bits (102), Expect = 5e-04 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R R R+RDR + R +R R R++ + E + + AR E D Sbjct: 671 RRDERARERDRERERDRERERERERERDRER-EKERELERERAREREREREKERDRERDR 729 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADR 387 R D E + E E + E+E+ + + ++ RE++R R+R R+RA +R Sbjct: 730 DRDHDRERERERERDREKEREREREERERERERERERERERERERERARER 780 Score = 41.2 bits (95), Expect = 0.003 Identities = 29/111 (26%), Positives = 52/111 (46%), Gaps = 1/111 (0%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R + R RDR+R + R +R R+ ++ + E + D E D + D + Sbjct: 679 RDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERE 738 Query: 337 F-RSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAAD 386 R D E + E E + R+R + + + + ++ RE+ R RD+ R+R D Sbjct: 739 RERERDREKEREREREERERERERERERERERERERERARERDKERERQRD 789 Score = 34.3 bits (77), Expect = 0.40 Identities = 42/196 (21%), Positives = 80/196 (40%), Gaps = 17/196 (8%) Query: 280 PRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSEND-------- 331 P +RD+ + F+R G +R + + P + + R D E D Sbjct: 609 PERDNRDQARDSSFER--RHGERDRRDNRERDQRPSSPI-RHQGRNDELERDERREERRV 665 Query: 332 DAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFA 391 D D R + + D R+R + + D + +K RE +R R R R+R ++ + Sbjct: 666 DRVDDRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKER-- 723 Query: 392 CSVCKFRSFD-DEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQE 450 + R D D + ++ + + +E R + ++ E +E R ++ E+ R+ Sbjct: 724 ---DRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARER 780 Query: 451 LMEKETAKPKPDPFKG 466 E+E + D KG Sbjct: 781 DKERERQRDWEDKDKG 796 Score = 33.9 bits (76), Expect = 0.52 Identities = 86/433 (19%), Positives = 153/433 (35%), Gaps = 56/433 (12%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R + R DR+R + R DR R+ ++ + E + + R E D Sbjct: 727 RDRDRDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERER 786 Query: 337 FRSGDEEFKGEDELCDSGRQ----RGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFAC 392 R +++ KG D+ + + R ++ DE K+R + R R + + Sbjct: 787 QRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSP 846 Query: 393 SVCKFRSFDDEEIQKH--LQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKR--- 447 + S DD+ +KH L + R +S P E Q ++K E++ Sbjct: 847 DSDAYNSGDDKN-EKHRLLSQVVRPQESRSLS---PSHLTEDRQGRWKEEDRKPERKESS 902 Query: 448 ----RQELMEKETAKPKPDPFKGIGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHLHSVD 503 QEL EK ++ K Q + +E++ A D++ Q R Sbjct: 903 RRYEEQELKEKVSSVDK--------QREQTEILESSRMRAQDII--GHHQSEDRETSDRA 952 Query: 504 HNHNRRLAAEQFKKTSLHVAKSVLNNRHIVKMLEK------YLKGEDPFTSETVDPEMEG 557 H+ N++ A Q K V R ++ + KG+ + E + +G Sbjct: 953 HDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKSIEKKRKKSKG 1012 Query: 558 DDNLGGEDKKE---------TPEEVAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEG 608 D ++ E+ + TP + L E+ ++ + + ++++ Sbjct: 1013 DSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQKKEDTAFSDWSDEDV 1072 Query: 609 P--TDTAEA---------GSDPQ-AEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETM 656 P T+ EA GS P LL P TA VP + AA A + Sbjct: 1073 PDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVP--ATLAATTAAAATSF 1130 Query: 657 AAEAESAQTRVAP 669 + A + T P Sbjct: 1131 STSAITISTSATP 1143 Score = 30.0 bits (66), Expect = 7.5 Identities = 13/33 (39%), Positives = 20/33 (60%) Query: 355 RQRGEKEDEDEDVKKRREKQRRRDRTRDRAADR 387 RQR D D+D + R++ R R+R R+R D+ Sbjct: 1319 RQREWDRDADKDWPRNRDRDRLRERERERERDK 1351 >gi|46409304 glutamate-rich 1 [Homo sapiens] Length = 443 Score = 43.5 bits (101), Expect = 7e-04 Identities = 38/123 (30%), Positives = 52/123 (42%), Gaps = 13/123 (10%) Query: 543 EDPFTSETVDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESSGE 602 ED + DP + G+ ED K+T EE AD E +T RA EGA A E Sbjct: 208 EDGVDTSEEDPTLAGE-----EDVKDTREEDGADASEEDLT---RARQEEGADASEEDPT 259 Query: 603 PAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEAES 662 PA +E D +A + + + E+ G E G + A+A T A E E Sbjct: 260 PAGEE---DVKDAREEDGVDTIEEDLTRAG--EEDGKDTREEDGADASEEDPTWAGEEEG 314 Query: 663 AQT 665 A + Sbjct: 315 ADS 317 >gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] Length = 2400 Score = 43.1 bits (100), Expect = 9e-04 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 17/160 (10%) Query: 541 KGEDPFTSETVDPEMEGDDNLGGE--DKKETPEEV---AADVLAEVITAAVRAVDGEGAP 595 +G + +E E EG E + +E EE + DV A + + +GE P Sbjct: 1936 EGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQP 1995 Query: 596 ------APESSGE--PAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAA 647 APE+ GE AE+E ++ + P++E ++V T +G + S+ Sbjct: 1996 ESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGV 2055 Query: 648 EAGNGAETMAAEAESAQTRVAPAPAAADAEVEQTDAESKD 687 EA E EA+ A+ V A A E E DA+ + Sbjct: 2056 EAPEAEE----EAQEAEGEVQEAEGEAHPESEDVDAQEAE 2091 Score = 40.4 bits (93), Expect = 0.006 Identities = 44/161 (27%), Positives = 64/161 (39%), Gaps = 25/161 (15%) Query: 541 KGEDPFTSETVD-PEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAPAPES 599 +GE SE V+ PE EG+ ED ETPE +V E EGA APE+ Sbjct: 1864 EGEAQPESEDVEAPEAEGEAQPESEDV-ETPE-AEWEVQPE----------SEGAEAPEA 1911 Query: 600 ---------SGEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGV---PKARSEAA 647 S E E EG + G++ Q + ++ T E V +A EA Sbjct: 1912 EKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQ 1971 Query: 648 EAGNGAETMAAEAESAQTRVAPAPAAADAEVEQTDAESKDA 688 E + E E+ + P + D E + + E ++A Sbjct: 1972 PESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEA 2012 Score = 37.4 bits (85), Expect = 0.047 Identities = 41/158 (25%), Positives = 64/158 (40%), Gaps = 10/158 (6%) Query: 541 KGEDPFTSETVD-PEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDG----EGAP 595 +GE SE ++ PE EG+ E + E A +E I A + EG Sbjct: 2122 EGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVE 2181 Query: 596 APESSGEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARS-EAAEAGNGAE 654 APE+ GE + + EA + Q E E V A E+ P+ E EA A+ Sbjct: 2182 APEAEGEAQPESEGIEAPEAEGEAQPEL---EGVEAPEAEEEAQPEPEGVETPEAEGEAQ 2238 Query: 655 TMAAEAESAQTRVAPAPAAADAEVEQTDAESKDAVPTE 692 + + + +P + D + E+ +ES VP + Sbjct: 2239 PESEGETQGEKKGSPQVSLGDGQSEEA-SESSSPVPED 2275 Score = 35.8 bits (81), Expect = 0.14 Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 28/163 (17%) Query: 557 GDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEG---------------APAPESSG 601 GD + G D E E A+ A+ + V A + EG APE+ G Sbjct: 1822 GDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEG 1881 Query: 602 EPAEDEGPTDTAEA----------GSDPQAEQLLEEQVPCGTAHE-KGVPKARSEAAEAG 650 E + +T EA P+AE+ + + A E +G + SE AEA Sbjct: 1882 EAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEA- 1940 Query: 651 NGAETMAAEAESAQTRVAPAPAAADAEVE-QTDAESKDAVPTE 692 AE A EAE + + +AE E Q ++E +A+ E Sbjct: 1941 QEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVE 1983 Score = 35.8 bits (81), Expect = 0.14 Identities = 43/162 (26%), Positives = 60/162 (37%), Gaps = 15/162 (9%) Query: 541 KGEDPFTSETVDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVDGEGAP----- 595 +GE+ E + EGD D E PE A+ A+ V+ +GE P Sbjct: 2030 EGEEAQEVEGETQKTEGDAQ-PESDGVEAPE---AEEEAQEAEGEVQEAEGEAHPESEDV 2085 Query: 596 -APESSGEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKG----VPKARSEAAEAG 650 A E+ GE + + EA + Q + +E G A + P+A EA Sbjct: 2086 DAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPES 2145 Query: 651 NGAETMAAEAESAQTRVAPAPAAADAEVEQTDAESKDAVPTE 692 G E AE E AQ A E Q + E +A E Sbjct: 2146 EGVEAQDAEGE-AQPESEGIEAQEAEEEAQPELEGVEAPEAE 2186 Score = 34.7 bits (78), Expect = 0.30 Identities = 32/145 (22%), Positives = 52/145 (35%), Gaps = 16/145 (11%) Query: 556 EGDDNLGGE----DKKETPEEVAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEGPTD 611 EG+D G + DK E D +A+ + E + E E EG ++ Sbjct: 1742 EGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTH--NSETSAGSELGEAEQEGEGISE 1799 Query: 612 TAEAGSDPQA-EQLLEEQVPCGTAHEKG---------VPKARSEAAEAGNGAETMAAEAE 661 E G E L+ + G + G P+A EA G E AE + Sbjct: 1800 RGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGD 1859 Query: 662 SAQTRVAPAPAAADAEVEQTDAESK 686 + + P + D E + + E++ Sbjct: 1860 AQEAEGEAQPESEDVEAPEAEGEAQ 1884 Score = 32.0 bits (71), Expect = 2.0 Identities = 25/98 (25%), Positives = 38/98 (38%), Gaps = 4/98 (4%) Query: 598 ESSGEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARS----EAAEAGNGA 653 E GEPA+ + + G DP+ E L G +GVP+ + A A GA Sbjct: 1001 EGLGEPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGAAPEGVSEAPAEAGA 1060 Query: 654 ETMAAEAESAQTRVAPAPAAADAEVEQTDAESKDAVPT 691 + A R P +A ++ + SK P+ Sbjct: 1061 DREAPAGCRVSLRALPGRVSASTQIMRALMGSKQGRPS 1098 Score = 30.0 bits (66), Expect = 7.5 Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 9/89 (10%) Query: 598 ESSGEPAEDEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGV--PKARSEAAEAGNGAET 655 E++ +D G +D AE P+AE + + +GV P+A +A EA A+ Sbjct: 1817 EAAAGGDQDPGQSDGAEGIEAPEAEGEAQPE-------SEGVEAPEAEGDAQEAEGEAQP 1869 Query: 656 MAAEAESAQTRVAPAPAAADAEVEQTDAE 684 + + E+ + P + D E + + E Sbjct: 1870 ESEDVEAPEAEGEAQPESEDVETPEAEWE 1898 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 42.7 bits (99), Expect = 0.001 Identities = 67/322 (20%), Positives = 129/322 (40%), Gaps = 39/322 (12%) Query: 355 RQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFH 414 R+R + + + + +K RE++R RDR RDR +R + + R D + + ++K Sbjct: 325 REREREREREREKEKERERERERDRDRDRTKERDR---DRDRERDRDRDRERSSDRNKDR 381 Query: 415 KETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKETAKPK----------PDPF 464 + + ++ E +E R ++ E+ R+ E+E + K D + Sbjct: 382 SRSREKSRDREREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAY 441 Query: 465 KGIGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAK 524 + E ++ EAA+ Q +L + AE+ ++ +AK Sbjct: 442 ERRKLERKLREKEAAY----------QERLKNWEIRERKKTREYEKEAEREEERRREMAK 491 Query: 525 SVLNNRHIVKMLE------KYLKGED-PFTSETVDPEMEGDDNLGGEDKKETPEEVAADV 577 + ++ + KY +G + EME D+ +K+E EE+ + Sbjct: 492 EAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEEL-EEIRQRL 550 Query: 578 LAE---VITAAVRAV--DGEGAPAPESSGEP---AEDEGPTDTAEAGSDPQAEQLLEEQV 629 LAE A ++ + + E P+ EP E+E + E +P E+ EQ Sbjct: 551 LAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610 Query: 630 PCGTAHEKGVPKARSEAAEAGN 651 PC + + A S ++ +GN Sbjct: 611 PCLKPTLRPISSAPSVSSASGN 632 Score = 42.7 bits (99), Expect = 0.001 Identities = 85/429 (19%), Positives = 163/429 (37%), Gaps = 79/429 (18%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R + R RDRDR K R DR D E D + + + D Sbjct: 343 RERERDRDRDRTKERDRDR--------------------------DRERDRDRDRERSSD 376 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCK 396 R+ D + ++ D R+R + + + + ++ RE++R R+R R+R +R + + Sbjct: 377 -RNKDRS-RSREKSRDREREREREREREREREREREREREREREREREREREK---DKKR 431 Query: 397 FRSFDDEE------IQKHLQSK--FHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRR 448 R D+E+ +++ L+ K ++E L+ + KT +EY ++ E+RR Sbjct: 432 DREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKT----REYEKEAEREEERRR 487 Query: 449 QELMEKETAKPKPDPFKGIGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHLHSVDHNHNR 508 + E + K + + + + + A Q +L R +R Sbjct: 488 EMAKEAKRLKEFLEDYDDDRDDPKYYRGSA-----------LQKRLRDREKEMEADERDR 536 Query: 509 RLAAEQFKKTSLHVAKSVLNNRH------IVKMLEKYLKGEDPFTSETVDPEMEGDDNLG 562 + E+ ++ + + +L H + +M ++ + P + + E E ++ Sbjct: 537 KREKEELEE----IRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQE 592 Query: 563 GEDKKETP-EEVAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEGPTDTAEAGSDPQA 621 E+K+E P EE + +R + AP+ S+ A P D + G Sbjct: 593 KEEKREEPMEEEEEPEQKPCLKPTLRPI--SSAPSVSSASGNATPNTPGDESPCGIIIPH 650 Query: 622 EQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEAESAQTRVAPAPAAADAEVEQT 681 E ++Q P E+ PK GA + S + + P D+ + Sbjct: 651 ENSPDQQQP-----EEHRPKI---GLSLKLGASNSPGQPNSVKRKKLP----VDSVFNKF 698 Query: 682 DAESKDAVP 690 + E D VP Sbjct: 699 EDEDSDDVP 707 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 42.7 bits (99), Expect = 0.001 Identities = 40/180 (22%), Positives = 80/180 (44%), Gaps = 24/180 (13%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R + R R+R + +++G +R + +KR++ + +E + K R E G Sbjct: 73 REKERKRERGKKEKKG-ERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGK 131 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCK 396 R EE K E+ R E+E + E+ +K RE++ R+ R R + ++ Sbjct: 132 ERERKEERKREE--------RKERERKKEEREKERERKERKKRERKQVGEK--------- 174 Query: 397 FRSFDDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKET 456 EE +K + K K+ R + ++ + +E R KK E++++ +++T Sbjct: 175 ------EEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228 Score = 37.0 bits (84), Expect = 0.061 Identities = 30/105 (28%), Positives = 52/105 (49%), Gaps = 2/105 (1%) Query: 355 RQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFH 414 R+ G+KE E E K+RRE+++R+ R R++ R + R ++ E +K + K + Sbjct: 48 RKEGKKERESERKKERREREKRK-REREKERKRERGKKEKKGERKKEERERKKRRREKEN 106 Query: 415 KETLRFISTKLPDKTVE-FLQEYIVNRNKKIEKRRQELMEKETAK 458 KE K +K + R +K E++R+E E+E K Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151 >gi|84872173 zinc finger protein 131 [Homo sapiens] Length = 589 Score = 42.7 bits (99), Expect = 0.001 Identities = 48/223 (21%), Positives = 82/223 (36%), Gaps = 35/223 (15%) Query: 480 HCLACDMLIPAQPQLLQRHLHSVDHNHNRRLAAEQFKKTSLHVAKSVLNNR--------- 530 HC CD+ Q L+RHL HN + RL E+ V + + Sbjct: 387 HCTLCDLWF-MQGNELRRHLSDA-HNISERLVTEEVLSVETRVQTEPVTSMTIIEQVGKV 444 Query: 531 HIVKMLEKYLKGEDPFTSETVDPEMEGDDNLGGEDKKETPEEVAADVLAEVITAAVRAVD 590 H++ +L+ + T E V P++ D + E PE+V L ++ + Sbjct: 445 HVLPLLQVQVDSAQ-VTVEQVHPDLLQDSQVHDSHMSELPEQVQVSYLE---VGRIQTEE 500 Query: 591 GEGAPAPESSGEPAED---EGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPKARSEAA 647 G E E E T+ EA D +++ ++ + S A Sbjct: 501 GTEVHVEELHVERVNQMPVEVQTELLEADLDHVTPEIMNQE------------ERESSQA 548 Query: 648 EAGNGAETMAAEAESAQTRVAPAPAAADAEVEQTDAESKDAVP 690 +A A +AE +T+ D+E E+ + E + A+P Sbjct: 549 DAAEAAREDHEDAEDLETK-----PTVDSEAEKAENEDRTALP 586 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 42.4 bits (98), Expect = 0.001 Identities = 54/231 (23%), Positives = 95/231 (41%), Gaps = 36/231 (15%) Query: 231 GGRGLGGPSPSRPPPSLF-SQSMAPDYGVMGMQGAGGYDSTMPYGCGRSQPRMRDRDRPK 289 GG+ LG SP + P L S + AP + G + T+P R R+ ++ P+ Sbjct: 6 GGQSLGNSSPVKTSPLLVPSLTYAPH--LHSSLGTLWVEVTIPLDFSRG--RLGSQESPR 61 Query: 290 RRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSGDEEFKGEDE 349 G + D G R++ E D + + E D R D E + +++ Sbjct: 62 SWGLGQAHKDADGDDRQR-----ERDRVREKTEKERDRD---------RKRDRERRRKEK 107 Query: 350 LCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHL 409 + R R ++ + + D + REKQ+ R+R RDR +R D E ++ Sbjct: 108 ETNRNRDREKQTEIERD--REREKQKGRERERDRGRER----------ERDRDREKERER 155 Query: 410 QSKFHKETLRFISTKLP-----DKTVEFLQEYIVNRNKKIEKRRQELMEKE 455 Q++ ++ R T+ +K E E +R + EK R+ ++E Sbjct: 156 QTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRE 206 Score = 38.1 bits (87), Expect = 0.028 Identities = 38/130 (29%), Positives = 57/130 (43%), Gaps = 24/130 (18%) Query: 277 RSQPRMRDRDRPKRRGF----DRFGPDGTGRKR-------KQFQLYEEPDTKLARVDSEG 325 R + R RDRDR K R DR G T +R KQ + E D R D+E Sbjct: 139 RGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQR-DTEK 197 Query: 326 DFSENDDAAGDF-------RSGDEEFKGEDELC-----DSGRQRGEKEDEDEDVKKRREK 373 + D D R + + +GE E R RG++ D + D K+ R+K Sbjct: 198 ERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERKK 257 Query: 374 QRRRDRTRDR 383 +R+++R ++R Sbjct: 258 ERKKERKKER 267 Score = 35.8 bits (81), Expect = 0.14 Identities = 30/107 (28%), Positives = 48/107 (44%), Gaps = 14/107 (13%) Query: 283 RDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSGDE 342 RDR+R K++G +R GR+R++ + E+ + D +G + R D Sbjct: 123 RDREREKQKGRER--ERDRGRERERDRDREKERERQTEKDRDGQRETETE-----RERDR 175 Query: 343 EFKGEDELCDSGRQRGEKEDEDEDVKKRREKQ--RRRDRTRDRAADR 387 E + + E R+ D D +K RE+Q R RDR R +R Sbjct: 176 EREKQKE-----RETERDRDRQRDTEKERERQTDRERDRQRKTQTER 217 Score = 32.7 bits (73), Expect = 1.2 Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 9/105 (8%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 R + R RD ++ + R DR + +++ Q + E D + R + D G Sbjct: 187 RDRDRQRDTEKERERQTDR---ERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGK 243 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTR 381 R + + K E ++ +KE + E +K++E++RR D+ R Sbjct: 244 ERDRERDRKEER------KKERKKERKKERKEKKKEEKRREDKKR 282 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 42.0 bits (97), Expect = 0.002 Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 33/134 (24%) Query: 279 QPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFR 338 + + R+++R + R DR G +R++ + E ++ S + D GD R Sbjct: 307 EAKEREKERRRSRSIDR------GLERRRSRSRERHRSR----------SRSRDRKGDRR 350 Query: 339 SGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFR 398 D E + E+E RG + D D D ++ E+++ R+R+R+R+ ++ R Sbjct: 351 DRDREREKENE-------RGRRRDRDYDKERGNEREKERERSRERSKEQ----------R 393 Query: 399 SFDDEEIQKHLQSK 412 S + E +KH + K Sbjct: 394 SRGEVEEKKHKEDK 407 Score = 40.4 bits (93), Expect = 0.006 Identities = 38/148 (25%), Positives = 63/148 (42%), Gaps = 3/148 (2%) Query: 274 GCGRSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSE-GDFSENDD 332 G R + R R+R R + R DR G D R R++ + E + D E G+ E + Sbjct: 324 GLERRRSRSRERHRSRSRSRDRKG-DRRDRDREREKENERGRRRDRDYDKERGNEREKER 382 Query: 333 AAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRA-ADRIQFA 391 RS ++ +GE E + ++ D+ ++EK+ R R+R+R R + Sbjct: 383 ERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSR 442 Query: 392 CSVCKFRSFDDEEIQKHLQSKFHKETLR 419 + + RS E+ KH K R Sbjct: 443 NAGKRSRSRSKEKSSKHKNESKEKSNKR 470 Score = 30.8 bits (68), Expect = 4.4 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 7/56 (12%) Query: 339 SGDEEFKGEDELCDSGRQRGEKEDE-------DEDVKKRREKQRRRDRTRDRAADR 387 S D E + E E R+ E+E E D +++RR + R R R+R R+ DR Sbjct: 290 SFDRELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDR 345 >gi|56606114 trichohyalin-like 1 [Homo sapiens] Length = 904 Score = 42.0 bits (97), Expect = 0.002 Identities = 59/275 (21%), Positives = 99/275 (36%), Gaps = 27/275 (9%) Query: 440 RNKKIEKRRQELMEKETAKPKPDPFKGIGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHL 499 + ++ K R ++E +T K +G+ + +K L+ + P+L + Sbjct: 405 QKERDRKTRPLVLETQTQDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAV 464 Query: 500 HSVDHNHNRRLAAEQFKKT-SLHVAKSVLNNRHIVK---MLEKYLKGEDPFTSETVDPEM 555 + H + AE F + + A+ L R + LEK GE+ ++T D + Sbjct: 465 SGEEAEHTKEGTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKTHDQPV 524 Query: 556 EGDDNLGGED-----------KKETPEEVAADVLAEVITAAVRAVDGEGAPAPESSGEPA 604 E +D GED ETP +A++ V G+ + GE Sbjct: 525 EEEDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQGDQHGESV 584 Query: 605 E--DEGPTDTAEAGSDPQAEQLLEEQVPCGTAHEKGVPK-----ARSEAAEAGNGAETMA 657 + DT G+ + + LE VP + + + AR E G G + Sbjct: 585 QGGHNNNPDTQRQGTPGEKNRALEAVVPAVRGEDVQLTEDQEQPARGEHKNQGPGTKGPG 644 Query: 658 AEAE-----SAQTRVAPAPAAADAEVEQTDAESKD 687 A E AQ A E+E T A +D Sbjct: 645 AAVEPNGHPEAQESTAGDENRKSLEIEITGALDED 679 >gi|21735569 claspin [Homo sapiens] Length = 1339 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/87 (34%), Positives = 46/87 (52%), Gaps = 7/87 (8%) Query: 329 ENDDAAGDFR--SGDEEFKG-EDELCDSGRQ---RGEKEDEDEDVKKRREKQRRRDRTRD 382 + ++ GDFR S D EF EDE DSG ++D++E++ KR EK +R+ R R Sbjct: 993 DEEEEFGDFRLVSNDNEFDSDEDEHSDSGNDLALEDHEDDDEEELLKRSEKLKRQMRLRK 1052 Query: 383 RAADRIQFACS-VCKFRSFDDEEIQKH 408 D + + S V +D EEI ++ Sbjct: 1053 YLEDEAEVSGSDVGSEDEYDGEEIDEY 1079 Score = 35.8 bits (81), Expect = 0.14 Identities = 21/90 (23%), Positives = 48/90 (53%), Gaps = 11/90 (12%) Query: 318 LARVDSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRR 377 L ++D+E F E ++ EE + DE + G ++ EKE+++E++++ EK+ Sbjct: 619 LFKLDNEDGFEEEEE---------EEEEMTDESEEDGEEKVEKEEKEEELEEEEEKEEEE 669 Query: 378 DRTRDRAADRIQFACSVCKFRSFDDEEIQK 407 + ++ + +F S + + D++E+ K Sbjct: 670 EEEGNQ--ETAEFLLSSEEIETKDEKEMDK 697 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 41.6 bits (96), Expect = 0.002 Identities = 38/175 (21%), Positives = 78/175 (44%), Gaps = 9/175 (5%) Query: 281 RMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSG 340 R RDR+R + R DR T R+ ++ + E + + E D D Sbjct: 48 RQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDR---HTET 104 Query: 341 DEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSF 400 D E + + E + R R + ++ +++ + R+ R DR R+R A+R + + R Sbjct: 105 DRERQKQKER-EMERVRDREREKQKEMGRERQTDRETDRERERQAERER---ETGRERKT 160 Query: 401 DDEEIQKHLQSKFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQELMEKE 455 +D ++ + K +E R TK ++ + +E ++K +++R+ E++ Sbjct: 161 EDRHRERERERKRERERKR--ETKERERHTDMERERQRETDRKRDRQRESERERD 213 Score = 40.0 bits (92), Expect = 0.007 Identities = 30/128 (23%), Positives = 55/128 (42%), Gaps = 5/128 (3%) Query: 338 RSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKF 397 R +E K ED + RQR + + + D + REKQ R+ R R +R + + Sbjct: 31 RDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETER 90 Query: 398 RSFDDEEIQKHLQS-----KFHKETLRFISTKLPDKTVEFLQEYIVNRNKKIEKRRQELM 452 + E +H ++ K + + + + +K E +E +R E+ RQ Sbjct: 91 ERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAER 150 Query: 453 EKETAKPK 460 E+ET + + Sbjct: 151 ERETGRER 158 Score = 37.0 bits (84), Expect = 0.061 Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 18/124 (14%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYE-------EPDTKLAR---VDSEGD 326 R + R +R+R K R DR R++++ + E E ++ R D E D Sbjct: 82 RDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDREREKQKEMGRERQTDRETD 141 Query: 327 FSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKR-------REKQRRRDR 379 A + +G E K ED + R+R + + + K+R RE+QR DR Sbjct: 142 RERERQAERERETGRER-KTEDRHRERERERKRERERKRETKERERHTDMERERQRETDR 200 Query: 380 TRDR 383 RDR Sbjct: 201 KRDR 204 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 5/107 (4%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 RS R R R + +RR R+R++ + K R D+ E + Sbjct: 336 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK--RKDTREKIKEKERVKEK 393 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDR 383 R + E + E E ++RG+ +D D++ +K REK + +DR R+R Sbjct: 394 DREKEREREKERE---KEKERGKNKDRDKEREKDREKDKEKDRERER 437 Score = 39.7 bits (91), Expect = 0.009 Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 1/111 (0%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 + + + R+R + + R R T K K+ + +E D + R + E + Sbjct: 356 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 415 Query: 337 FRSGDEEFKGE-DELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAAD 386 R + E E D+ D R+R ++ ++D D +K +E+ + ++R +DR+ + Sbjct: 416 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 466 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 41.6 bits (96), Expect = 0.002 Identities = 29/107 (27%), Positives = 49/107 (45%), Gaps = 5/107 (4%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 RS R R R + +RR R+R++ + K R D+ E + Sbjct: 220 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK--RKDTREKIKEKERVKEK 277 Query: 337 FRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDR 383 R + E + E E ++RG+ +D D++ +K REK + +DR R+R Sbjct: 278 DREKEREREKERE---KEKERGKNKDRDKEREKDREKDKEKDRERER 321 Score = 39.7 bits (91), Expect = 0.009 Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 1/111 (0%) Query: 277 RSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDAAGD 336 + + + R+R + + R R T K K+ + +E D + R + E + Sbjct: 240 KKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNK 299 Query: 337 FRSGDEEFKGE-DELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAAD 386 R + E E D+ D R+R ++ ++D D +K +E+ + ++R +DR+ + Sbjct: 300 DRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKE 350 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 40.8 bits (94), Expect = 0.004 Identities = 55/236 (23%), Positives = 88/236 (37%), Gaps = 44/236 (18%) Query: 269 STMPYGCGRSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFS 328 S P R R R R ++R D G R R + EG Sbjct: 30 SVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSK----------------EGRRH 73 Query: 329 ENDDAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQ-------------- 374 E+ D + + EE ++ D GR+R + ED KR+E++ Sbjct: 74 ESKDKSSK-KHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRE 132 Query: 375 -RRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRFIST-----KLPDK 428 R R R+R+R R + + K RS E + +S+ K +R S + + Sbjct: 133 RRHRSRSRERKKSRSR-SRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTR 191 Query: 429 TVEFLQEYIVNRNKKIEKRRQELMEKETAKPKPDPFKG-----IGQEHFFKKIEAA 479 + + +R K+IEK R+ + P P PF+G QE +++E A Sbjct: 192 SRSRTRSRSRDRKKRIEKPRR-FSRSLSRTPSPPPFRGRNTAMDAQEALARRLERA 246 >gi|41406057 amyloid beta A4 protein isoform c precursor [Homo sapiens] Length = 695 Score = 40.4 bits (93), Expect = 0.006 Identities = 60/267 (22%), Positives = 107/267 (40%), Gaps = 46/267 (17%) Query: 310 LYEEPDTKLARVDSEGDFSEN--DDAAGDFRSGDE----EFKGEDELCDSGRQRGEKEDE 363 L EE D + D+E D S+ A D+ G E E E+E+ + E+ D+ Sbjct: 189 LAEESDN-VDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEE---EEADD 244 Query: 364 DEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRFIST 423 DED + E + + + A +R + + EE+ + + + Sbjct: 245 DEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVR----------VPTTAA 294 Query: 424 KLPDKTVEFLQE--------YIVNRNKKIEKRRQELMEK---------ETAKPKPDPFKG 466 PD ++L+ + +++E + +E M + AK P K Sbjct: 295 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 354 Query: 467 IGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHLHSVDH--NHNRRLAAEQFKKTSLHVAK 524 +HF +K+E+ A + + QL++ H+ V+ N RRLA E + T+L Sbjct: 355 AVIQHFQEKVESLEQEAAN----ERQQLVETHMARVEAMLNDRRRLALENYI-TALQAVP 409 Query: 525 SVLNNRHIVKMLEKYLKGEDPFTSETV 551 RH+ ML+KY++ E T+ Sbjct: 410 P--RPRHVFNMLKKYVRAEQKDRQHTL 434 >gi|209915570 amyloid beta A4 protein isoform e precursor [Homo sapiens] Length = 639 Score = 40.4 bits (93), Expect = 0.006 Identities = 60/267 (22%), Positives = 107/267 (40%), Gaps = 46/267 (17%) Query: 310 LYEEPDTKLARVDSEGDFSEN--DDAAGDFRSGDE----EFKGEDELCDSGRQRGEKEDE 363 L EE D + D+E D S+ A D+ G E E E+E+ + E+ D+ Sbjct: 133 LAEESDN-VDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEE---EEADD 188 Query: 364 DEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRFIST 423 DED + E + + + A +R + + EE+ + + + Sbjct: 189 DEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVR----------VPTTAA 238 Query: 424 KLPDKTVEFLQE--------YIVNRNKKIEKRRQELMEK---------ETAKPKPDPFKG 466 PD ++L+ + +++E + +E M + AK P K Sbjct: 239 STPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKK 298 Query: 467 IGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHLHSVDH--NHNRRLAAEQFKKTSLHVAK 524 +HF +K+E+ A + + QL++ H+ V+ N RRLA E + T+L Sbjct: 299 AVIQHFQEKVESLEQEAAN----ERQQLVETHMARVEAMLNDRRRLALENYI-TALQAVP 353 Query: 525 SVLNNRHIVKMLEKYLKGEDPFTSETV 551 RH+ ML+KY++ E T+ Sbjct: 354 P--RPRHVFNMLKKYVRAEQKDRQHTL 378 >gi|153070260 myristoylated alanine-rich protein kinase C substrate [Homo sapiens] Length = 332 Score = 40.4 bits (93), Expect = 0.006 Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 12/132 (9%) Query: 564 EDKKETPEEVAADVLA------EVITAAVRAVDGEGAPAPESSGEPAEDEGPTDTAEAGS 617 ++KKE E A+ A E A A GA + E + P E+ + AG Sbjct: 173 KNKKEAGEGGEAEAPAAEGGKDEAAGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGG 232 Query: 618 DPQAEQLLEEQVPCGTAHEKGVPKARSEAAEAGNGAETMAAEAESAQTRVAPAPAAA--D 675 DPQ + E V A EK ++AAE + E AE A AP+AA Sbjct: 233 DPQEAKPQEAAV----APEKPPASDETKAAEEPSKVEEKKAEEAGASAAACEAPSAAGPG 288 Query: 676 AEVEQTDAESKD 687 A EQ A +++ Sbjct: 289 APPEQEAAPAEE 300 Score = 37.0 bits (84), Expect = 0.061 Identities = 42/165 (25%), Positives = 61/165 (36%), Gaps = 22/165 (13%) Query: 545 PFTSETVDPEMEGDDNLGGED-KKETPEEVAADVLAEVITAAVRAVDGEGAPAPESSGEP 603 P +E +P G +KE P E A AE + A +GE A A S+ P Sbjct: 82 PSAAEKGEPAAAAAPEAGASPVEKEAPAEGEA---AE--PGSPTAAEGEAASAASSTSSP 136 Query: 604 AEDEGPTDTAEAGSDPQAEQLL--------------EEQVPCGTAHEKGVPKARSEAAEA 649 ++G T + + + ++ + + G E P A EA Sbjct: 137 KAEDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEA 196 Query: 650 GNGAETMAAEAESAQTRVAPAPA--AADAEVEQTDAESKDAVPTE 692 GA AAEA +A A AP AA E + ++A P E Sbjct: 197 AGGAAAAAAEAGAASGEQAAAPGEEAAAGEEGAAGGDPQEAKPQE 241 >gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma) [Homo sapiens] Length = 526 Score = 40.4 bits (93), Expect = 0.006 Identities = 78/334 (23%), Positives = 106/334 (31%), Gaps = 89/334 (26%) Query: 3 QGYGGYGAWSAGPANTQGAYGTGVASWQGYENYNYYGAQNTSVTTGATYSYGPASWEAAK 62 Q Y GY +T G YG S G YG Q+T G+T YG S ++++ Sbjct: 36 QSYSGYSQ----STDTSG-YGQSSYSSYGQSQNTGYGTQSTPQGYGSTGGYG--SSQSSQ 88 Query: 63 ANDGGLAAGAPAMHMASYGPEPCTDNSDSLIAKINQRLDMMSKEGGRGGSGGGGEGIQDR 122 ++ G ++ YG +P S G G S Q + Sbjct: 89 SSYGQQSS------YPGYGQQPAPS----------------STSGSYGSSSQSSSYGQPQ 126 Query: 123 ESSFRFQPFESY-DSRPCLPEHNPYRPSYSY----DYEFDLGSDRNGSFGGQYSECRDPA 177 S+ QP SY + + Y P Y Y G G GG Y + + Sbjct: 127 SGSYSQQP--SYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSM 184 Query: 178 RERGSLDGFMRGRGQGRFQDRSNPGTFMRSDPFVPPAASSEPLSTPWNELNYVGGRGLGG 237 G G G G G + + D GGRG GG Sbjct: 185 SSGGGSGG---GYGNQDQSGGGGSGGYGQQDR---------------------GGRGRGG 220 Query: 238 PSPSRPPPSLFSQSMAPDYGVMGMQGAGGYDSTMPYGCGRSQPRMRDRDRPKRRGFDRFG 297 G G G GGY+ + G +PR R R R G Sbjct: 221 S------------------GGGGGGGGGGYNRS----SGGYEPRGRGGGRGGRGGMG--- 255 Query: 298 PDGTGRKRKQFQLYEEPDTKLARVDSEGDFSEND 331 G R F + P + +R DSE D S+N+ Sbjct: 256 ----GSDRGGFNKFGGPRDQGSRHDSEQDNSDNN 285 >gi|31317305 M-phase phosphoprotein 10 [Homo sapiens] Length = 681 Score = 40.0 bits (92), Expect = 0.007 Identities = 57/280 (20%), Positives = 117/280 (41%), Gaps = 37/280 (13%) Query: 306 KQFQLYEEPDTKLARVDSEGDFSENDDAAGDFRSGDEEFK-GEDELCDSGRQRGEKEDED 364 K+ + ++ D + +D D ++D G F G ++ K G+ + + + D Sbjct: 219 KEEERKDDNDEEEEDIDFFEDIDSDEDEGGLF--GSKKLKSGKSSRNLKYKDFFDPVESD 276 Query: 365 EDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKETLRFISTK 424 ED+ + + ++ D A+ S+ + + +D+++Q++ +K HKE+L+ ++ Sbjct: 277 EDITNVHDDELDSNKEDDEIAEEEAEELSISE--TDEDDDLQENEDNKQHKESLKRVTFA 334 Query: 425 LPD------------------------KTVEFLQEYIVNRNKK-IEKRRQELMEKETAKP 459 LPD K E + E I + K+ +EK+ +L + TA+ Sbjct: 335 LPDDAETEDTGVLNVKKNSDEVKSSFEKRQEKMNEKIASLEKELLEKKPWQLQGEVTAQK 394 Query: 460 KPDPFKGIGQEHFFKKIEAAHCLACDMLIPAQPQLLQRHLHS-----VDHNHNRRLAAEQ 514 +P+ HF + A + + + + + QR V + A E Sbjct: 395 RPENSLLEETLHFDHAVRMAPVITEETTLQLEDIIKQRIRDQAWDDVVRKEKPKEDAYEY 454 Query: 515 FKKTSLHVAKSVLNNRHIVKMLEKYLKGEDPFTSETVDPE 554 K+ +L KS L+ I + ++Y+K T+E +PE Sbjct: 455 KKRLTLDHEKSKLSLAEIYE--QEYIKLNQQKTAEEENPE 492 >gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] Length = 2240 Score = 39.7 bits (91), Expect = 0.009 Identities = 33/126 (26%), Positives = 51/126 (40%), Gaps = 26/126 (20%) Query: 262 QGAGGYDSTMPYGCGRSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARV 321 QG D GR+ R RD DRP R +DR Sbjct: 2106 QGRASEDRRRERERGRNWSRERDWDRP--REWDRHRDK---------------------- 2141 Query: 322 DSEGDFSENDDAAGDFRSGDEEFKGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTR 381 DS D+ N + + + E +G++ D R+R + + D ++ R++ R R+R R Sbjct: 2142 DSSRDWDRNRERSANRDREREADRGKE--WDRSRERSRNRERERDRRRDRDRSRSRERDR 2199 Query: 382 DRAADR 387 D+A DR Sbjct: 2200 DKARDR 2205 >gi|239746922 PREDICTED: similar to cancer/testis antigen family 147, member B1 isoform 2 [Homo sapiens] Length = 294 Score = 39.3 bits (90), Expect = 0.012 Identities = 34/122 (27%), Positives = 53/122 (43%), Gaps = 2/122 (1%) Query: 571 EEVAADVLAEVITAAVRAVDGEGAPAPESSGEPAEDEGPTDTAEAGSDPQAEQLLEEQVP 630 EE ++ E + +GEG + + E E P D AE +P AE+ EE+ Sbjct: 156 EEPRLLLVHERLGVGAAGPEGEGLGLLQEAALVPEPEVPADLAEMAREP-AEEPAEEKPT 214 Query: 631 CGTAHEKGVPKARSEAAEAGNGAETMAAEAESAQTRVAPAPAAADAEVEQTDAESKDAVP 690 A E+ +A E A+ AE +AE + + AP + E+ D E++DA Sbjct: 215 EEAAEEELAEEAAEEPAKEEPAAEEESAEEPATEEAAAP-EEVTKYQHEKWDEEAQDAAG 273 Query: 691 TE 692 E Sbjct: 274 KE 275 >gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens] Length = 871 Score = 39.3 bits (90), Expect = 0.012 Identities = 26/120 (21%), Positives = 52/120 (43%), Gaps = 3/120 (2%) Query: 274 GCGRSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDA 333 G G + + D+D K G K K+ + + D + + DSE + ++ Sbjct: 294 GLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE--GDGDKEEKKEDSEKEAKKSSKK 351 Query: 334 AGDFRSGDEEF-KGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFAC 392 SGD+ F +G +S + G+ E+E E+ + +EK++ ++ ++ D C Sbjct: 352 RNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLEC 411 Score = 29.6 bits (65), Expect = 9.8 Identities = 17/55 (30%), Positives = 28/55 (50%) Query: 347 EDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFD 401 +DE R + +E D D + R+++RR D DR DR + S ++R +D Sbjct: 5 DDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYD 59 Score = 29.6 bits (65), Expect = 9.8 Identities = 20/97 (20%), Positives = 43/97 (44%), Gaps = 2/97 (2%) Query: 322 DSEGDFSENDDAAGDFRSGDEEFKGEDEL--CDSGRQRGEKEDEDEDVKKRREKQRRRDR 379 D E ++ D+ D + + + +D+ + + EK+++ E K+ K+R R Sbjct: 297 DGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356 Query: 380 TRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKE 416 + D + D + S + S EE ++ ++ KE Sbjct: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKE 393 >gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens] Length = 875 Score = 39.3 bits (90), Expect = 0.012 Identities = 26/120 (21%), Positives = 52/120 (43%), Gaps = 3/120 (2%) Query: 274 GCGRSQPRMRDRDRPKRRGFDRFGPDGTGRKRKQFQLYEEPDTKLARVDSEGDFSENDDA 333 G G + + D+D K G K K+ + + D + + DSE + ++ Sbjct: 294 GLGDGERKTNDKDEKKEDGKQAENDSSNDDKTKKSE--GDGDKEEKKEDSEKEAKKSSKK 351 Query: 334 AGDFRSGDEEF-KGEDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFAC 392 SGD+ F +G +S + G+ E+E E+ + +EK++ ++ ++ D C Sbjct: 352 RNRKHSGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAAGLEC 411 Score = 29.6 bits (65), Expect = 9.8 Identities = 17/55 (30%), Positives = 28/55 (50%) Query: 347 EDELCDSGRQRGEKEDEDEDVKKRREKQRRRDRTRDRAADRIQFACSVCKFRSFD 401 +DE R + +E D D + R+++RR D DR DR + S ++R +D Sbjct: 5 DDEYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYD 59 Score = 29.6 bits (65), Expect = 9.8 Identities = 20/97 (20%), Positives = 43/97 (44%), Gaps = 2/97 (2%) Query: 322 DSEGDFSENDDAAGDFRSGDEEFKGEDEL--CDSGRQRGEKEDEDEDVKKRREKQRRRDR 379 D E ++ D+ D + + + +D+ + + EK+++ E K+ K+R R Sbjct: 297 DGERKTNDKDEKKEDGKQAENDSSNDDKTKKSEGDGDKEEKKEDSEKEAKKSSKKRNRKH 356 Query: 380 TRDRAADRIQFACSVCKFRSFDDEEIQKHLQSKFHKE 416 + D + D + S + S EE ++ ++ KE Sbjct: 357 SGDDSFDEGSVSESESESESGQAEEEKEEAEALKEKE 393 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.131 0.389 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,794,642 Number of Sequences: 37866 Number of extensions: 1807985 Number of successful extensions: 13476 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 126 Number of HSP's successfully gapped in prelim test: 517 Number of HSP's that attempted gapping in prelim test: 10190 Number of HSP's gapped (non-prelim): 2521 length of query: 692 length of database: 18,247,518 effective HSP length: 109 effective length of query: 583 effective length of database: 14,120,124 effective search space: 8232032292 effective search space used: 8232032292 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.