Search of human proteins with 4885281

Search of human proteins with 4885281

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885281 glutamate dehydrogenase 1 [Homo sapiens]
         (558 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885281 glutamate dehydrogenase 1 [Homo sapiens]                  1125   0.0  
gi|31377775 glutamate dehydrogenase 2 [Homo sapiens]                 1077   0.0  
gi|239755340 PREDICTED: similar to hCG2040250 [Homo sapiens]           43   7e-04
gi|4505725 peroxin1 [Homo sapiens]                                     33   0.53 
gi|55770868 tubulin, beta polypeptide 4, member Q [Homo sapiens]       33   0.53 
gi|189095271 phospholipase A2, group VII [Homo sapiens]                31   2.6  
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]        31   2.6  
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]        31   2.6  
gi|4759182 syntaxin 1A (brain) [Homo sapiens]                          31   3.4  
gi|116256451 amine oxidase (flavin containing) domain 1 [Homo sa...    30   5.8  
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]                30   7.6  
gi|4758902 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4...    29   10.0 
gi|63175652 CREBBP/EP300 inhibitor 2 [Homo sapiens]                    29   10.0 

>gi|4885281 glutamate dehydrogenase 1 [Homo sapiens]
          Length = 558

 Score = 1125 bits (2909), Expect = 0.0
 Identities = 558/558 (100%), Positives = 558/558 (100%)

Query: 1   MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADR 60
           MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADR
Sbjct: 1   MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADR 60

Query: 61  EDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF 120
           EDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF
Sbjct: 61  EDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF 120

Query: 121 PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG 180
           PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG
Sbjct: 121 PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG 180

Query: 181 GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY 240
           GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY
Sbjct: 181 GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY 240

Query: 241 ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG 300
           ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG
Sbjct: 241 ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG 300

Query: 301 DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG 360
           DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG
Sbjct: 301 DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG 360

Query: 361 FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER 420
           FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER
Sbjct: 361 FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER 420

Query: 421 NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK 480
           NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK
Sbjct: 421 NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK 480

Query: 481 HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV 540
           HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV
Sbjct: 481 HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV 540

Query: 541 NAIEKVFKVYNEAGVTFT 558
           NAIEKVFKVYNEAGVTFT
Sbjct: 541 NAIEKVFKVYNEAGVTFT 558


>gi|31377775 glutamate dehydrogenase 2 [Homo sapiens]
          Length = 558

 Score = 1077 bits (2786), Expect = 0.0
 Identities = 534/558 (95%), Positives = 545/558 (97%)

Query: 1   MYRYLGEALLLSRAGPAALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADR 60
           MYRYL +ALL SRAGPAALGSA+  SAALLG  RGQPAAA QPGLALAARRHYSE VADR
Sbjct: 1   MYRYLAKALLPSRAGPAALGSAANHSAALLGRGRGQPAAASQPGLALAARRHYSELVADR 60

Query: 61  EDDPNFFKMVEGFFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSF 120
           EDDPNFFKMVEGFFDRGASIVEDKLV+DLRT+ESEEQKRNRVRGILRIIKPCNHVLSLSF
Sbjct: 61  EDDPNFFKMVEGFFDRGASIVEDKLVKDLRTQESEEQKRNRVRGILRIIKPCNHVLSLSF 120

Query: 121 PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG 180
           PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG
Sbjct: 121 PIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFG 180

Query: 181 GAKAGVKINPKNYTDNELEKITRRFTMELAKKGFIGPGIDVPAPDMSTGEREMSWIADTY 240
           GAKAGVKINPKNYT+NELEKITRRFTMELAKKGFIGPG+DVPAPDM+TGEREMSWIADTY
Sbjct: 181 GAKAGVKINPKNYTENELEKITRRFTMELAKKGFIGPGVDVPAPDMNTGEREMSWIADTY 240

Query: 241 ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFG 300
           ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGF 
Sbjct: 241 ASTIGHYDINAHACVTGKPISQGGIHGRISATGRGVFHGIENFINEASYMSILGMTPGFR 300

Query: 301 DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG 360
           DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG
Sbjct: 301 DKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESDGSIWNPDGIDPKELEDFKLQHGSILG 360

Query: 361 FPKAKPYEGSILEADCDILIPAASEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER 420
           FPKAKPYEGSILE DCDILIPAA+EKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER
Sbjct: 361 FPKAKPYEGSILEVDCDILIPAATEKQLTKSNAPRVKAKIIAEGANGPTTPEADKIFLER 420

Query: 421 NIMVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGK 480
           NI+VIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLL+SVQESLERKFGK
Sbjct: 421 NILVIPDLYLNAGGVTVSYFEWLKNLNHVSYGRLTFKYERDSNYHLLLSVQESLERKFGK 480

Query: 481 HGGTIPIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAYV 540
           HGGTIPIVPTAEFQD ISGASEKDIVHS LAYTMERSARQIM TAMKYNLGLDLRTAAYV
Sbjct: 481 HGGTIPIVPTAEFQDSISGASEKDIVHSALAYTMERSARQIMHTAMKYNLGLDLRTAAYV 540

Query: 541 NAIEKVFKVYNEAGVTFT 558
           NAIEKVFKVY+EAGVTFT
Sbjct: 541 NAIEKVFKVYSEAGVTFT 558


>gi|239755340 PREDICTED: similar to hCG2040250 [Homo sapiens]
          Length = 180

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 21/23 (91%), Positives = 21/23 (91%)

Query: 153 STDVSVDEVKALASLMTYKCAVV 175
           S DVSVDEVK LASLMTYKCAVV
Sbjct: 156 SIDVSVDEVKTLASLMTYKCAVV 178


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score = 33.5 bits (75), Expect = 0.53
 Identities = 26/85 (30%), Positives = 36/85 (42%), Gaps = 16/85 (18%)

Query: 64  PNFFKMVEG--FFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLS-- 119
           P F   VEG  F D+G ++ E              QK     G    +KPC+HV+S    
Sbjct: 55  PAFLSWVEGRHFSDQGENVAE--------INRQVGQKLGLSNGGQVFLKPCSHVVSCQQV 106

Query: 120 --FPIRRDDGSWEVIEGYRAQHSQH 142
              P+  DD  WE++E +     QH
Sbjct: 107 EVEPLSADD--WEILELHAVSLEQH 129


>gi|55770868 tubulin, beta polypeptide 4, member Q [Homo sapiens]
          Length = 434

 Score = 33.5 bits (75), Expect = 0.53
 Identities = 18/54 (33%), Positives = 27/54 (50%), Gaps = 4/54 (7%)

Query: 171 KCAVVDVPFGGAKAGVKINPKNYTDNELEKITRRFTMELAKKGFI----GPGID 220
           K AV D+P  G K  V     N    EL++++ +FT    +K F+    G G+D
Sbjct: 350 KTAVCDIPPWGLKMSVTFTGNNTAVQELKRVSEQFTATFRRKAFLHWYTGEGMD 403


>gi|189095271 phospholipase A2, group VII [Homo sapiens]
          Length = 441

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 22/110 (20%)

Query: 73  FFDRGASIVEDKLVEDLRTRESEEQKRNRVRGILRIIKPCNHVLSLSFPIRRDDGSWEVI 132
           F D+ A+ + DK    LRT + EE+   R   + +  K C+  LSL   I          
Sbjct: 190 FKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDI---------- 239

Query: 133 EGYRAQHSQHRTPCKGGIRYSTDVSVDEVKALASLMTYKCAVVDVPFGGA 182
                    H  P K  +    D+  D  +   S+   K AV+   FGGA
Sbjct: 240 --------DHGKPVKNAL----DLKFDMEQLKDSIDREKIAVIGHSFGGA 277


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 42/171 (24%), Positives = 64/171 (37%), Gaps = 13/171 (7%)

Query: 331 GESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTK 390
           GE+DG    P   +P  L       G +   P+A    G  LEA+  + +  A       
Sbjct: 52  GETDGQQSAPQADEPP-LPPPPPPPGELARSPEAV---GPELEAEEKLSVRVAESAAAAP 107

Query: 391 SNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGG-VTVSYF----EWLKN 445
              P +     +     P   E ++  L +   V P L   AGG  TVS      E    
Sbjct: 108 QGGPELPPSPASPPEQPPAPEEREEPPLPQP--VAPALVPPAGGDSTVSQLIPGSEVRVT 165

Query: 446 LNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDR 496
           L+H+    L   +       L   V   L ++FG HG  + + P  E++D+
Sbjct: 166 LDHIIEDALVVSFRFGEK--LFSGVLMDLSKRFGPHGIPVTVFPKREYKDK 214


>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
          Length = 560

 Score = 31.2 bits (69), Expect = 2.6
 Identities = 42/171 (24%), Positives = 64/171 (37%), Gaps = 13/171 (7%)

Query: 331 GESDGSIWNPDGIDPKELEDFKLQHGSILGFPKAKPYEGSILEADCDILIPAASEKQLTK 390
           GE+DG    P   +P  L       G +   P+A    G  LEA+  + +  A       
Sbjct: 52  GETDGQQSAPQADEPP-LPPPPPPPGELARSPEAV---GPELEAEEKLSVRVAESAAAAP 107

Query: 391 SNAPRVKAKIIAEGANGPTTPEADKIFLERNIMVIPDLYLNAGG-VTVSYF----EWLKN 445
              P +     +     P   E ++  L +   V P L   AGG  TVS      E    
Sbjct: 108 QGGPELPPSPASPPEQPPAPEEREEPPLPQP--VAPALVPPAGGDSTVSQLIPGSEVRVT 165

Query: 446 LNHVSYGRLTFKYERDSNYHLLMSVQESLERKFGKHGGTIPIVPTAEFQDR 496
           L+H+    L   +       L   V   L ++FG HG  + + P  E++D+
Sbjct: 166 LDHIIEDALVVSFRFGEK--LFSGVLMDLSKRFGPHGIPVTVFPKREYKDK 214


>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
          Length = 288

 Score = 30.8 bits (68), Expect = 3.4
 Identities = 29/110 (26%), Positives = 48/110 (43%), Gaps = 11/110 (10%)

Query: 50  RRHYSEAVADREDDPNFFKMVEGFFD--RGASIVEDKLVEDLRTRESEEQKRNRVRGILR 107
           R+H +   +   D+    ++ E   D  + A+ V  KL + +     +E+  NR    LR
Sbjct: 56  RKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKL-KSIEQSIEQEEGLNRSSADLR 114

Query: 108 IIKPCNHVLSLSFPIRRDDGSWEVIEGYRAQHSQHRTPCKGGIRYSTDVS 157
           I K  +  LS  F         EV+  Y A  S +R  CKG I+   +++
Sbjct: 115 IRKTQHSTLSRKFV--------EVMSEYNATQSDYRERCKGRIQRQLEIT 156


>gi|116256451 amine oxidase (flavin containing) domain 1 [Homo
           sapiens]
          Length = 590

 Score = 30.0 bits (66), Expect = 5.8
 Identities = 14/44 (31%), Positives = 23/44 (52%), Gaps = 3/44 (6%)

Query: 299 FGDKTFVVQGFGNVGLHSMRYLHRFGAKCIAVGESD---GSIWN 339
           + +K+ ++ G G  GL + R LH FG K   +   D   G +W+
Sbjct: 248 YHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWD 291


>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
          Length = 639

 Score = 29.6 bits (65), Expect = 7.6
 Identities = 24/62 (38%), Positives = 27/62 (43%), Gaps = 3/62 (4%)

Query: 6  GEALLLSRAGPAALGSASADSAALL---GWARGQPAAAPQPGLALAARRHYSEAVADRED 62
          G ALL   A  AA   ASA SA  +   G A GQ  A+P PGL       +  A A    
Sbjct: 9  GLALLCCAAAAAAAAVASAASAGNVTGGGGAAGQVDASPGPGLRGEPSHPFPRATAPTAQ 68

Query: 63 DP 64
           P
Sbjct: 69 AP 70


>gi|4758902 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
           [Homo sapiens]
          Length = 469

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 28/128 (21%), Positives = 57/128 (44%), Gaps = 14/128 (10%)

Query: 432 AGGVTVSYFEWLKNLNHVSYG---RLTFKYERDSNYHLLMSVQESLERKFGKHGGTI--- 485
           A  + V Y +W K LN +  G    +T++  +D NY L  ++++  + ++    G     
Sbjct: 311 AEALGVPYEQW-KVLNEIDAGVCEEMTYEEIQD-NYPLEFALRDQDKYRYRYPKGESYED 368

Query: 486 ------PIVPTAEFQDRISGASEKDIVHSGLAYTMERSARQIMRTAMKYNLGLDLRTAAY 539
                 P++   E Q+ +     + ++   LAY ++++A Q+       +  L L   AY
Sbjct: 369 LVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKAAEQLPYLKCPLHTVLKLTPVAY 428

Query: 540 VNAIEKVF 547
              +E +F
Sbjct: 429 GCKVESIF 436


>gi|63175652 CREBBP/EP300 inhibitor 2 [Homo sapiens]
          Length = 236

 Score = 29.3 bits (64), Expect = 10.0
 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 3/57 (5%)

Query: 8   ALLLSRAGP---AALGSASADSAALLGWARGQPAAAPQPGLALAARRHYSEAVADRE 61
           A+  +R GP   A  G  +A  AA    ARG P AA     A AA R    A A RE
Sbjct: 46  AMAAARGGPVPAAREGRMAAARAAPAAAARGAPVAAAALARAAAAGRESPAAAAARE 102


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.136    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,182,549
Number of Sequences: 37866
Number of extensions: 978174
Number of successful extensions: 2249
Number of sequences better than 10.0: 13
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 2245
Number of HSP's gapped (non-prelim): 13
length of query: 558
length of database: 18,247,518
effective HSP length: 107
effective length of query: 451
effective length of database: 14,195,856
effective search space: 6402331056
effective search space used: 6402331056
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.