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Search of human proteins with 48717263
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48717263 speckle-type POZ protein-like [Homo sapiens]
(392 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48717263 speckle-type POZ protein-like [Homo sapiens] 798 0.0
gi|56117834 speckle-type POZ protein [Homo sapiens] 647 0.0
gi|56117832 speckle-type POZ protein [Homo sapiens] 647 0.0
gi|56117830 speckle-type POZ protein [Homo sapiens] 647 0.0
gi|56117828 speckle-type POZ protein [Homo sapiens] 647 0.0
gi|4507183 speckle-type POZ protein [Homo sapiens] 647 0.0
gi|56117836 speckle-type POZ protein [Homo sapiens] 647 0.0
gi|170784846 kelch-like 7 isoform 1 [Homo sapiens] 85 1e-16
gi|170784844 kelch-like 7 isoform 2 [Homo sapiens] 84 3e-16
gi|223468659 kelch repeat and BTB (POZ) domain containing 2 [Hom... 79 9e-15
gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens] 78 1e-14
gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens] 78 1e-14
gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens] 75 8e-14
gi|55925608 kelch-like 21 [Homo sapiens] 74 2e-13
gi|38194229 kelch-like 17 [Homo sapiens] 74 3e-13
gi|109150407 kelch-like 6 [Homo sapiens] 72 7e-13
gi|8922528 kelch-like 11 [Homo sapiens] 70 3e-12
gi|45333883 kelch repeat and BTB (POZ) domain-containing 6 [Homo... 70 4e-12
gi|21359972 kelch repeat and BTB (POZ) domain containing 7 [Homo... 69 6e-12
gi|166235129 kelch-like 3 [Homo sapiens] 68 1e-11
gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens] 68 2e-11
gi|239835720 kelch-like 2, Mayven isoform 1 [Homo sapiens] 68 2e-11
gi|194097389 kelch-like 38 [Homo sapiens] 67 3e-11
gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo... 67 4e-11
gi|47717139 leucine-zipper-like transcription regulator 1 [Homo ... 66 5e-11
gi|57863304 inhibitor of Bruton's tyrosine kinase [Homo sapiens] 66 5e-11
gi|209571547 kelch repeat and BTB (POZ) domain containing 4 isof... 65 1e-10
gi|209693446 kelch repeat and BTB (POZ) domain containing 4 isof... 65 1e-10
gi|21956639 ankyrin repeat and BTB (POZ) domain containing 2 [Ho... 65 1e-10
gi|227497736 T-cell activation kelch repeat protein [Homo sapiens] 64 2e-10
>gi|48717263 speckle-type POZ protein-like [Homo sapiens]
Length = 392
Score = 798 bits (2060), Expect = 0.0
Identities = 392/392 (100%), Positives = 392/392 (100%)
Query: 1 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG 60
MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG
Sbjct: 1 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG 60
Query: 61 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ 120
PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ
Sbjct: 61 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ 120
Query: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK 180
RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK
Sbjct: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK 180
Query: 181 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR 240
VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR
Sbjct: 181 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR 240
Query: 241 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE
Sbjct: 241 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
Query: 301 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI 360
NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI
Sbjct: 301 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI 360
Query: 361 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS 392
QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS
Sbjct: 361 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS 392
>gi|56117834 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 647 bits (1670), Expect = 0.0
Identities = 316/392 (80%), Positives = 349/392 (89%), Gaps = 18/392 (4%)
Query: 1 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG 60
MSR P+PP P +MS+GP+AESWCYTQ+KVVKFSYMWTINNFSFCREEMGEV+KSSTFSSG
Sbjct: 1 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 60
Query: 61 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ 120
+DK+KWCLRVNPKGLD+ESKDYLSLYLLLVSCPKSEVRAKFKFS+LNAK EETKAMESQ
Sbjct: 61 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 120
Query: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK 180
RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISG N +K
Sbjct: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 180
Query: 181 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR 240
VPECRLA++LG LWEN+RFTDC V GQEF+AHK++LAARSPVF+AMFEHEMEESKKNR
Sbjct: 181 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 240
Query: 241 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
VEIND++PEVFKEMM FIYTG+APNLDKMAD+LLAAADKYALERLKVMCE+ALCSNLSVE
Sbjct: 241 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 300
Query: 301 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI 360
N A+ L+LADLHSA+QLK QA+DFIN A+D++ETSGWKSM+
Sbjct: 301 NAAEILILADLHSADQLKTQAVDFIN------------------YHASDVLETSGWKSMV 342
Query: 361 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS 392
SHPHLVAEA+R+LASAQCP G PRKRLKQS
Sbjct: 343 VSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS 374
>gi|56117832 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 647 bits (1670), Expect = 0.0
Identities = 316/392 (80%), Positives = 349/392 (89%), Gaps = 18/392 (4%)
Query: 1 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG 60
MSR P+PP P +MS+GP+AESWCYTQ+KVVKFSYMWTINNFSFCREEMGEV+KSSTFSSG
Sbjct: 1 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 60
Query: 61 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ 120
+DK+KWCLRVNPKGLD+ESKDYLSLYLLLVSCPKSEVRAKFKFS+LNAK EETKAMESQ
Sbjct: 61 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 120
Query: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK 180
RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISG N +K
Sbjct: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 180
Query: 181 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR 240
VPECRLA++LG LWEN+RFTDC V GQEF+AHK++LAARSPVF+AMFEHEMEESKKNR
Sbjct: 181 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 240
Query: 241 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
VEIND++PEVFKEMM FIYTG+APNLDKMAD+LLAAADKYALERLKVMCE+ALCSNLSVE
Sbjct: 241 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 300
Query: 301 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI 360
N A+ L+LADLHSA+QLK QA+DFIN A+D++ETSGWKSM+
Sbjct: 301 NAAEILILADLHSADQLKTQAVDFIN------------------YHASDVLETSGWKSMV 342
Query: 361 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS 392
SHPHLVAEA+R+LASAQCP G PRKRLKQS
Sbjct: 343 VSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS 374
>gi|56117830 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 647 bits (1670), Expect = 0.0
Identities = 316/392 (80%), Positives = 349/392 (89%), Gaps = 18/392 (4%)
Query: 1 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG 60
MSR P+PP P +MS+GP+AESWCYTQ+KVVKFSYMWTINNFSFCREEMGEV+KSSTFSSG
Sbjct: 1 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 60
Query: 61 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ 120
+DK+KWCLRVNPKGLD+ESKDYLSLYLLLVSCPKSEVRAKFKFS+LNAK EETKAMESQ
Sbjct: 61 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 120
Query: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK 180
RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISG N +K
Sbjct: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 180
Query: 181 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR 240
VPECRLA++LG LWEN+RFTDC V GQEF+AHK++LAARSPVF+AMFEHEMEESKKNR
Sbjct: 181 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 240
Query: 241 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
VEIND++PEVFKEMM FIYTG+APNLDKMAD+LLAAADKYALERLKVMCE+ALCSNLSVE
Sbjct: 241 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 300
Query: 301 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI 360
N A+ L+LADLHSA+QLK QA+DFIN A+D++ETSGWKSM+
Sbjct: 301 NAAEILILADLHSADQLKTQAVDFIN------------------YHASDVLETSGWKSMV 342
Query: 361 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS 392
SHPHLVAEA+R+LASAQCP G PRKRLKQS
Sbjct: 343 VSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS 374
>gi|56117828 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 647 bits (1670), Expect = 0.0
Identities = 316/392 (80%), Positives = 349/392 (89%), Gaps = 18/392 (4%)
Query: 1 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG 60
MSR P+PP P +MS+GP+AESWCYTQ+KVVKFSYMWTINNFSFCREEMGEV+KSSTFSSG
Sbjct: 1 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 60
Query: 61 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ 120
+DK+KWCLRVNPKGLD+ESKDYLSLYLLLVSCPKSEVRAKFKFS+LNAK EETKAMESQ
Sbjct: 61 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 120
Query: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK 180
RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISG N +K
Sbjct: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 180
Query: 181 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR 240
VPECRLA++LG LWEN+RFTDC V GQEF+AHK++LAARSPVF+AMFEHEMEESKKNR
Sbjct: 181 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 240
Query: 241 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
VEIND++PEVFKEMM FIYTG+APNLDKMAD+LLAAADKYALERLKVMCE+ALCSNLSVE
Sbjct: 241 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 300
Query: 301 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI 360
N A+ L+LADLHSA+QLK QA+DFIN A+D++ETSGWKSM+
Sbjct: 301 NAAEILILADLHSADQLKTQAVDFIN------------------YHASDVLETSGWKSMV 342
Query: 361 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS 392
SHPHLVAEA+R+LASAQCP G PRKRLKQS
Sbjct: 343 VSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS 374
>gi|4507183 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 647 bits (1670), Expect = 0.0
Identities = 316/392 (80%), Positives = 349/392 (89%), Gaps = 18/392 (4%)
Query: 1 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG 60
MSR P+PP P +MS+GP+AESWCYTQ+KVVKFSYMWTINNFSFCREEMGEV+KSSTFSSG
Sbjct: 1 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 60
Query: 61 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ 120
+DK+KWCLRVNPKGLD+ESKDYLSLYLLLVSCPKSEVRAKFKFS+LNAK EETKAMESQ
Sbjct: 61 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 120
Query: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK 180
RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISG N +K
Sbjct: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 180
Query: 181 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR 240
VPECRLA++LG LWEN+RFTDC V GQEF+AHK++LAARSPVF+AMFEHEMEESKKNR
Sbjct: 181 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 240
Query: 241 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
VEIND++PEVFKEMM FIYTG+APNLDKMAD+LLAAADKYALERLKVMCE+ALCSNLSVE
Sbjct: 241 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 300
Query: 301 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI 360
N A+ L+LADLHSA+QLK QA+DFIN A+D++ETSGWKSM+
Sbjct: 301 NAAEILILADLHSADQLKTQAVDFIN------------------YHASDVLETSGWKSMV 342
Query: 361 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS 392
SHPHLVAEA+R+LASAQCP G PRKRLKQS
Sbjct: 343 VSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS 374
>gi|56117836 speckle-type POZ protein [Homo sapiens]
Length = 374
Score = 647 bits (1670), Expect = 0.0
Identities = 316/392 (80%), Positives = 349/392 (89%), Gaps = 18/392 (4%)
Query: 1 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG 60
MSR P+PP P +MS+GP+AESWCYTQ+KVVKFSYMWTINNFSFCREEMGEV+KSSTFSSG
Sbjct: 1 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG 60
Query: 61 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ 120
+DK+KWCLRVNPKGLD+ESKDYLSLYLLLVSCPKSEVRAKFKFS+LNAK EETKAMESQ
Sbjct: 61 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ 120
Query: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK 180
RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISG N +K
Sbjct: 121 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK 180
Query: 181 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR 240
VPECRLA++LG LWEN+RFTDC V GQEF+AHK++LAARSPVF+AMFEHEMEESKKNR
Sbjct: 181 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR 240
Query: 241 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
VEIND++PEVFKEMM FIYTG+APNLDKMAD+LLAAADKYALERLKVMCE+ALCSNLSVE
Sbjct: 241 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE 300
Query: 301 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI 360
N A+ L+LADLHSA+QLK QA+DFIN A+D++ETSGWKSM+
Sbjct: 301 NAAEILILADLHSADQLKTQAVDFIN------------------YHASDVLETSGWKSMV 342
Query: 361 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS 392
SHPHLVAEA+R+LASAQCP G PRKRLKQS
Sbjct: 343 VSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS 374
>gi|170784846 kelch-like 7 isoform 1 [Homo sapiens]
Length = 586
Score = 84.7 bits (208), Expect = 1e-16
Identities = 47/138 (34%), Positives = 73/138 (52%)
Query: 190 LGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPE 249
+ N+ + D V+ ++ AH+ VLAA S FN MF M ESK VE+ D +P+
Sbjct: 34 MNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPD 93
Query: 250 VFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLA 309
+ ++++ F YT R +LL AA++Y +E +K MC + L + N VLA
Sbjct: 94 IIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLA 153
Query: 310 DLHSAEQLKAQAIDFINR 327
+ +LKA A DFI++
Sbjct: 154 ECLDCPELKATADDFIHQ 171
>gi|170784844 kelch-like 7 isoform 2 [Homo sapiens]
Length = 564
Score = 83.6 bits (205), Expect = 3e-16
Identities = 50/134 (37%), Positives = 72/134 (53%), Gaps = 2/134 (1%)
Query: 196 NTRFTDCSFFVRGQEFK--AHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKE 253
N + T C + QE K AH+ VLAA S FN MF M ESK VE+ D +P++ ++
Sbjct: 16 NLKKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQ 75
Query: 254 MMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHS 313
++ F YT R +LL AA++Y +E +K MC + L + N VLA+
Sbjct: 76 LVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLD 135
Query: 314 AEQLKAQAIDFINR 327
+LKA A DFI++
Sbjct: 136 CPELKATADDFIHQ 149
>gi|223468659 kelch repeat and BTB (POZ) domain containing 2 [Homo
sapiens]
Length = 623
Score = 78.6 bits (192), Expect = 9e-15
Identities = 47/136 (34%), Positives = 63/136 (46%)
Query: 186 LAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEIND 245
L E L +E FTD V G EF HK VLA S F AMF + ESK+ V + +
Sbjct: 17 LLEQLKLFYEQQLFTDIVLIVEGTEFPCHKMVLATCSSYFRAMFMSGLSESKQTHVHLRN 76
Query: 246 LDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADT 305
+D + ++ + YTG D + L A +E + C E L ++ EN
Sbjct: 77 VDAATLQIIITYAYTGNLAMNDSTVEQLYETACFLQVEDVLQRCREYLIKKINAENCVRL 136
Query: 306 LVLADLHSAEQLKAQA 321
L ADL S E+LK A
Sbjct: 137 LSFADLFSCEELKQSA 152
>gi|151108413 BTB (POZ) domain containing 9 isoform a [Homo sapiens]
Length = 612
Score = 78.2 bits (191), Expect = 1e-14
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 4/146 (2%)
Query: 186 LAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESK-KNRVEIN 244
L+E +G L + D +F V + F AH+ +LAAR F A+ M ES+ + + +
Sbjct: 22 LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQ 81
Query: 245 DLDPEVFKEMMRFIYTGRAPNLDKMAD---NLLAAADKYALERLKVMCEEALCSNLSVEN 301
D E F ++++IYTGRA D+ + + L+ A KY L+ E LC+ L+++N
Sbjct: 82 DTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQN 141
Query: 302 VADTLVLADLHSAEQLKAQAIDFINR 327
V T +A L+S +L F++R
Sbjct: 142 VCMTFDVASLYSLPKLTCMCCMFMDR 167
>gi|151108411 BTB (POZ) domain containing 9 isoform a [Homo sapiens]
Length = 612
Score = 78.2 bits (191), Expect = 1e-14
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 4/146 (2%)
Query: 186 LAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESK-KNRVEIN 244
L+E +G L + D +F V + F AH+ +LAAR F A+ M ES+ + + +
Sbjct: 22 LSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQ 81
Query: 245 DLDPEVFKEMMRFIYTGRAPNLDKMAD---NLLAAADKYALERLKVMCEEALCSNLSVEN 301
D E F ++++IYTGRA D+ + + L+ A KY L+ E LC+ L+++N
Sbjct: 82 DTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQN 141
Query: 302 VADTLVLADLHSAEQLKAQAIDFINR 327
V T +A L+S +L F++R
Sbjct: 142 VCMTFDVASLYSLPKLTCMCCMFMDR 167
>gi|21362105 BTB/POZ KELCH domain protein [Homo sapiens]
Length = 589
Score = 75.5 bits (184), Expect = 8e-14
Identities = 46/137 (33%), Positives = 71/137 (51%), Gaps = 2/137 (1%)
Query: 182 PECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRV 241
P+C LA L L ++ FTD + + + F H++VLAA S F AMF H + ES+ + V
Sbjct: 29 PDCVLAH-LNTLRKHCMFTDVTLWAGDRAFPCHRAVLAASSRYFEAMFSHGLRESRDDTV 87
Query: 242 EIND-LDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE 300
D L PEV + ++ F Y+ R ++ A++LL A D ++ E L NL
Sbjct: 88 NFQDNLHPEVLELLLDFAYSSRIAINEENAESLLEAGDMLQFHDVRDAAAEFLEKNLFPS 147
Query: 301 NVADTLVLADLHSAEQL 317
N ++L+D H +L
Sbjct: 148 NCLGMMLLSDAHQCRRL 164
>gi|55925608 kelch-like 21 [Homo sapiens]
Length = 597
Score = 74.3 bits (181), Expect = 2e-13
Identities = 48/143 (33%), Positives = 70/143 (48%), Gaps = 1/143 (0%)
Query: 186 LAEDLGNLWENTRFTDCSFFVRG-QEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEIN 244
L L L +F D + G ++F AH++VLAA SP F AMF ++ ES+ RV ++
Sbjct: 21 LLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVLAAASPYFRAMFAGQLRESRAERVRLH 80
Query: 245 DLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVAD 304
+ P++ + ++ F YTGR A+ LL AAD +K C L L + N D
Sbjct: 81 GVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAADLLQFPAVKEACGAFLQQQLDLANCLD 140
Query: 305 TLVLADLHSAEQLKAQAIDFINR 327
A+ S L + A FI R
Sbjct: 141 MQDFAEAFSCSGLASAAQRFILR 163
>gi|38194229 kelch-like 17 [Homo sapiens]
Length = 642
Score = 73.6 bits (179), Expect = 3e-13
Identities = 42/125 (33%), Positives = 63/125 (50%)
Query: 201 DCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEMMRFIYT 260
D V +E +AHK VLA+ SP F+AMF +EM ES++ V ++D+DP+ ++++F YT
Sbjct: 93 DIVLHVAAKEIRAHKVVLASCSPYFHAMFTNEMSESRQTHVTLHDIDPQALDQLVQFAYT 152
Query: 261 GRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQ 320
+ LL AA L ++ C + L S L N AD HS L
Sbjct: 153 AEIVVGEGNVQTLLPAASLLQLNGVRDACCKFLLSQLDPSNCLGIRGFADAHSCSDLLKA 212
Query: 321 AIDFI 325
A ++
Sbjct: 213 AHRYV 217
>gi|109150407 kelch-like 6 [Homo sapiens]
Length = 621
Score = 72.4 bits (176), Expect = 7e-13
Identities = 46/140 (32%), Positives = 66/140 (47%)
Query: 186 LAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEIND 245
L L L TD V QEF H+ VLAA S F AMF ++++E + R+ I
Sbjct: 58 LQNGLETLRMENALTDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRIIIKG 117
Query: 246 LDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADT 305
+D E ++ + YT +A + +L AA+ + R+ C L L+ EN
Sbjct: 118 VDAETMHTLLDYTYTSKALITKQNVQRVLEAANLFQFLRMVDACASFLTEALNPENCVGI 177
Query: 306 LVLADLHSAEQLKAQAIDFI 325
L LAD HS + LK Q +I
Sbjct: 178 LRLADTHSLDSLKKQVQSYI 197
>gi|8922528 kelch-like 11 [Homo sapiens]
Length = 708
Score = 70.1 bits (170), Expect = 3e-12
Identities = 41/126 (32%), Positives = 64/126 (50%), Gaps = 6/126 (4%)
Query: 208 GQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDL------DPEVFKEMMRFIYTG 261
G+EF+AH+SVLAA + F + + ES+ RVE+ +P+ + ++ ++YTG
Sbjct: 105 GREFRAHRSVLAAATEYFTPLLSGQFSESRSGRVEMRKWSSEPGPEPDTVEAVIEYMYTG 164
Query: 262 RAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQA 321
R +L AD++ L RLK C E L L + N LA +++ QL +A
Sbjct: 165 RIRVSTGSVHEVLELADRFLLIRLKEFCGEFLKKKLHLSNCVAIHSLAHMYTLSQLALKA 224
Query: 322 IDFINR 327
D I R
Sbjct: 225 ADMIRR 230
>gi|45333883 kelch repeat and BTB (POZ) domain-containing 6 [Homo
sapiens]
Length = 674
Score = 69.7 bits (169), Expect = 4e-12
Identities = 39/118 (33%), Positives = 63/118 (53%)
Query: 208 GQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEMMRFIYTGRAPNLD 267
G+ F +++VLAA P F +MF M ES++ V ++D+D E F+ ++ + YTGR +
Sbjct: 79 GRLFPCNRNVLAAACPYFKSMFTGGMYESQQASVTMHDVDAESFEVLVDYCYTGRVSLSE 138
Query: 268 KMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFI 325
+ L AA+D LE ++ C L L + N L AD +L++QA +I
Sbjct: 139 ANVERLYAASDMLQLEYVREACASFLARRLDLTNCTAILKFADAFGHRKLRSQAQSYI 196
>gi|21359972 kelch repeat and BTB (POZ) domain containing 7 [Homo
sapiens]
Length = 684
Score = 69.3 bits (168), Expect = 6e-12
Identities = 39/118 (33%), Positives = 62/118 (52%)
Query: 208 GQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEMMRFIYTGRAPNLD 267
G+ F +++VLAA P F +MF M ES++ V ++D+D E F+ ++ + YTGR +
Sbjct: 79 GRLFSCNRNVLAAACPYFKSMFTGGMYESQQASVTMHDVDAESFEVLVDYCYTGRVSLSE 138
Query: 268 KMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQAIDFI 325
L AA+D LE ++ C L L + N L AD +L++QA +I
Sbjct: 139 ANVQRLYAASDMLQLEYVREACASFLARRLDLTNCTAILKFADAFDHHKLRSQAQSYI 196
>gi|166235129 kelch-like 3 [Homo sapiens]
Length = 587
Score = 68.2 bits (165), Expect = 1e-11
Identities = 40/112 (35%), Positives = 58/112 (51%)
Query: 210 EFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEMMRFIYTGRAPNLDKM 269
E +AH+ VLAA SP F AMF +M ESK ++EI D+D + +++ +IYT ++
Sbjct: 60 EIEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEEN 119
Query: 270 ADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQA 321
LL AA L ++ C + L S L N AD+H+ L QA
Sbjct: 120 VQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQA 171
>gi|239835722 kelch-like 2, Mayven isoform 2 [Homo sapiens]
Length = 597
Score = 67.8 bits (164), Expect = 2e-11
Identities = 41/121 (33%), Positives = 59/121 (48%)
Query: 201 DCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEMMRFIYT 260
D + E AH+ VLAA SP F+AMF EM ES+ RV I ++D + ++ ++YT
Sbjct: 61 DVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYT 120
Query: 261 GRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQ 320
++ LL AA L+ +K C E L S L N AD+H+ L +
Sbjct: 121 AEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNK 180
Query: 321 A 321
A
Sbjct: 181 A 181
>gi|239835720 kelch-like 2, Mayven isoform 1 [Homo sapiens]
Length = 593
Score = 67.8 bits (164), Expect = 2e-11
Identities = 41/121 (33%), Positives = 59/121 (48%)
Query: 201 DCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEMMRFIYT 260
D + E AH+ VLAA SP F+AMF EM ES+ RV I ++D + ++ ++YT
Sbjct: 57 DVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYT 116
Query: 261 GRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQLKAQ 320
++ LL AA L+ +K C E L S L N AD+H+ L +
Sbjct: 117 AEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNK 176
Query: 321 A 321
A
Sbjct: 177 A 177
>gi|194097389 kelch-like 38 [Homo sapiens]
Length = 581
Score = 67.0 bits (162), Expect = 3e-11
Identities = 39/136 (28%), Positives = 65/136 (47%)
Query: 186 LAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEIND 245
L L +L ++ TD S +E H++VLA+ SP F AMF E + +V++
Sbjct: 20 LLRQLNSLRQSRILTDVSICAGAREIPCHRNVLASSSPYFRAMFCSSFREKSEAKVQLKG 79
Query: 246 LDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADT 305
+DP +++ ++YTG A ++ AA +L C L S L+ N
Sbjct: 80 IDPPTLDQIVSYVYTGEAHIATDNVLPVMEAASMLQFPKLFEACSSYLQSQLAPSNCLGM 139
Query: 306 LVLADLHSAEQLKAQA 321
+ L+++ S E LK +A
Sbjct: 140 IRLSEILSCETLKKKA 155
>gi|4505461 ectodermal-neural cortex (with BTB-like domain) [Homo
sapiens]
Length = 589
Score = 66.6 bits (161), Expect = 4e-11
Identities = 41/129 (31%), Positives = 65/129 (50%), Gaps = 1/129 (0%)
Query: 190 LGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEI-NDLDP 248
L L + FTD + F H++VLAA S F AMF ++ES+ + V N + P
Sbjct: 36 LNLLRQQRLFTDVLLHAGNRTFPCHRAVLAACSRYFEAMFSGGLKESQDSEVNFDNSIHP 95
Query: 249 EVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVL 308
EV + ++ + Y+ R ++ A++LL A D + ++ C E L NL N L+L
Sbjct: 96 EVLELLLDYAYSSRVIINEENAESLLEAGDMLEFQDIRDACAEFLEKNLHPTNCLGMLLL 155
Query: 309 ADLHSAEQL 317
+D H +L
Sbjct: 156 SDAHQCTKL 164
>gi|47717139 leucine-zipper-like transcription regulator 1 [Homo
sapiens]
Length = 840
Score = 66.2 bits (160), Expect = 5e-11
Identities = 45/134 (33%), Positives = 66/134 (49%), Gaps = 11/134 (8%)
Query: 199 FTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDP--EVFKEMMR 256
F D + + G AHK++LAARS F AMF M E + + I ++ P + F+ M+R
Sbjct: 666 FCDITLLLDGHPRPAHKAILAARSSYFEAMFRSFMPEDGQVNISIGEMVPSRQAFESMLR 725
Query: 257 FIYTGRAPNLDKMADNLLAAADKYAL--ERLKVMCEEALCSNLSVENVADTLVLADLHSA 314
+IY G + + L AA Y RL+ C++ L N++V+NV L AD
Sbjct: 726 YIYYGEVNMPPEDSLYLFAAPYYYGFYNNRLQAYCKQNLEMNVTVQNVLQILEAAD---- 781
Query: 315 EQLKAQAIDFINRC 328
K QA+D C
Sbjct: 782 ---KTQALDMKRHC 792
Score = 53.5 bits (127), Expect = 3e-07
Identities = 51/223 (22%), Positives = 90/223 (40%), Gaps = 45/223 (20%)
Query: 157 LFCEVSVVQDSVNISGHTNTNTLK-----------VPECRLAEDLGNLWENTRFTDCSFF 205
LF +V+ D++ I G T N ++ P+C L ED G LWE+ +F D F
Sbjct: 389 LFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDYGRLWESRQFCDVEFV 448
Query: 206 VRGQE--FKAHKSVLAARSPVFNAMFEHEMEESKKN------------------------ 239
+ +E + H +++ ARS E +
Sbjct: 449 LGEKEECVQGHVAIVTARSRWLRRKITQARERLAQKLEQEAAPVPREAPGVAAGGARPPL 508
Query: 240 -RVEINDLDPEVFKEMMRFIYTGRA--PNLDKMADNLL-----AAADKYALERLKVMCEE 291
V I + + F+ +M+F+YT + P + D LL A + L RL+ +C +
Sbjct: 509 LHVAIREAEARPFEVLMQFLYTDKIKYPRKGHVEDVLLIMDVYKLALSFQLCRLEQLCRQ 568
Query: 292 ALCSNLSVENVADTLVLADLHSAEQLKAQAIDFINRCSVLRQL 334
+ +++ ++NV A QLK ++F+ + S Q+
Sbjct: 569 YIEASVDLQNVLVVCESAARLQLSQLKEHCLNFVVKESHFNQV 611
>gi|57863304 inhibitor of Bruton's tyrosine kinase [Homo sapiens]
Length = 1353
Score = 66.2 bits (160), Expect = 5e-11
Identities = 47/153 (30%), Positives = 78/153 (50%), Gaps = 15/153 (9%)
Query: 186 LAEDLGNLWENTRFTDCSFF-------VRGQEFKAHKSVLAARSPVFNAMFEHEMEESKK 238
+A++ GN + ++ CSF V G+EF HK VL AR F++M E+
Sbjct: 749 IAKNTGNKLKLSQ-KKCSFLCDVTMKSVDGKEFPCHKCVLCARLEYFHSMLSSSWIEASS 807
Query: 239 NRVEINDLDPEVFKEMMRFIYTGRA------PNLDKMADNLLAAADKYALERLKVMCEEA 292
+ ++ K ++ ++YT A N+D + ++L AD+ + RLK +CE A
Sbjct: 808 CAALEMPIHSDILKVILDYLYTDEAVVIKESQNVDFIC-SVLVVADQLLITRLKEICEVA 866
Query: 293 LCSNLSVENVADTLVLADLHSAEQLKAQAIDFI 325
L L+++N A L A ++SA+QLK + FI
Sbjct: 867 LTEKLTLKNAAMLLEFAAMYSAKQLKLSCLQFI 899
Score = 33.1 bits (74), Expect = 0.44
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 13/73 (17%)
Query: 201 DCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLD------------- 247
D +F V + F AHK +LA S F +F + S+ + D D
Sbjct: 565 DVTFQVGNRLFPAHKYILAVHSDFFQKLFLSDGNTSEFTDIYQKDEDSAGCHLFVVEKVH 624
Query: 248 PEVFKEMMRFIYT 260
P++F+ +++FIYT
Sbjct: 625 PDMFEYLLQFIYT 637
>gi|209571547 kelch repeat and BTB (POZ) domain containing 4 isoform
a [Homo sapiens]
Length = 534
Score = 65.1 bits (157), Expect = 1e-10
Identities = 37/127 (29%), Positives = 60/127 (47%)
Query: 195 ENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEM 254
E F D + V G+EF+ H+ VL+A+S F +MF ++E+ + + D+ VF+ +
Sbjct: 56 EEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLL 115
Query: 255 MRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSA 314
+ +IY G + + +D Y L L C L + V N + LAD HS
Sbjct: 116 VDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSD 175
Query: 315 EQLKAQA 321
+L A
Sbjct: 176 PELYTAA 182
>gi|209693446 kelch repeat and BTB (POZ) domain containing 4 isoform
b [Homo sapiens]
Length = 518
Score = 65.1 bits (157), Expect = 1e-10
Identities = 37/127 (29%), Positives = 60/127 (47%)
Query: 195 ENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVEINDLDPEVFKEM 254
E F D + V G+EF+ H+ VL+A+S F +MF ++E+ + + D+ VF+ +
Sbjct: 40 EEELFADVTISVEGREFQLHRLVLSAQSCFFRSMFTSNLKEAHNRVIVLQDVSESVFQLL 99
Query: 255 MRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSA 314
+ +IY G + + +D Y L L C L + V N + LAD HS
Sbjct: 100 VDYIYHGTVKLRAEELQEIYEVSDMYQLTSLFEECSRFLARTVQVGNCLQVMWLADRHSD 159
Query: 315 EQLKAQA 321
+L A
Sbjct: 160 PELYTAA 166
>gi|21956639 ankyrin repeat and BTB (POZ) domain containing 2 [Homo
sapiens]
Length = 839
Score = 64.7 bits (156), Expect = 1e-10
Identities = 60/226 (26%), Positives = 101/226 (44%), Gaps = 28/226 (12%)
Query: 112 EETKAMESQRAYRFVQGKDWGFKKFIRRDFLL---DEANGLLPDDKLTLFCEV------- 161
E + SQ Y VQ + RDF +E N L + L L ++
Sbjct: 564 ESLRTSFSQSRYSVVQS--------LLRDFSSIREEEYNEELVTEGLQLMFDILKTSKND 615
Query: 162 SVVQDSVNISGHT--NTNTLKVPECRL---AEDLGNLWENTRFTDCSFFVRGQEFKAHKS 216
SV+Q I H ++ +PE R A + N +D +F V G+ F AHK
Sbjct: 616 SVIQQLATIFTHCYGSSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKV 675
Query: 217 VLAARSPVFNAMFEHEMEES--KKNRVEINDLDPEVFKEMMRFIYTGRAPNLDKMADN-- 272
+L S F + ++ E+ +EI+D+ +F+ MM+++Y G +++ +
Sbjct: 676 LLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMQYLYYGGTESMEIPTTDIL 735
Query: 273 -LLAAADKYALERLKVMCEEALCSNLSVENVADTLVLADLHSAEQL 317
LL+AA + L+ L+ CE LS+E+ +T A +H+A +L
Sbjct: 736 ELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAKIHNAPEL 781
>gi|227497736 T-cell activation kelch repeat protein [Homo sapiens]
Length = 601
Score = 63.9 bits (154), Expect = 2e-10
Identities = 36/145 (24%), Positives = 71/145 (48%), Gaps = 1/145 (0%)
Query: 184 CRLAEDLGNLWENTRFTDCSFFV-RGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNRVE 242
C + + L +++ + TD V G+ F H++VLAA SP F +MF + ES + V
Sbjct: 33 CSILKQLKTMYDEGQLTDIVVEVDHGKTFSCHRNVLAAISPYFRSMFTSGLTESTQKEVR 92
Query: 243 INDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVENV 302
I ++ E ++ + YT R + L AA + + ++ C + + S+L +N
Sbjct: 93 IVGVEAESMDLVLNYAYTSRVILTEANVQALFTAASIFQIPSIQDQCAKYMISHLDPQNS 152
Query: 303 ADTLVLADLHSAEQLKAQAIDFINR 327
+ AD + ++L ++ ++I +
Sbjct: 153 IGVFIFADHYGHQELGDRSKEYIRK 177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.132 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,266,000
Number of Sequences: 37866
Number of extensions: 572915
Number of successful extensions: 1564
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 147
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 1328
Number of HSP's gapped (non-prelim): 198
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.