Guide to the Human Genome
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Search of human proteins with 13376142

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|13376142 nonhomologous end-joining factor 1 [Homo sapiens]
         (299 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|13376142 nonhomologous end-joining factor 1 [Homo sapiens]         598   e-171
gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]     35   0.10 
gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]     35   0.10 
gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]     35   0.10 
gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]     35   0.10 
gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]       35   0.10 
gi|119943102 CREB binding protein isoform b [Homo sapiens]             33   0.40 
gi|119943104 CREB binding protein isoform a [Homo sapiens]             33   0.40 
gi|59806363 hypothetical protein LOC9729 [Homo sapiens]                31   1.5  
gi|49087132 sal-like 2 [Homo sapiens]                                  30   2.6  
gi|8922122 elaC homolog 1 [Homo sapiens]                               30   3.4  
gi|157388975 coiled-coil domain containing 99 [Homo sapiens]           30   3.4  
gi|156938343 talin 2 [Homo sapiens]                                    29   4.4  
gi|51593088 neuroligin 3 [Homo sapiens]                                29   4.4  
gi|61966703 NHS-like 2 [Homo sapiens]                                  28   7.5  
gi|27734799 REST corepressor 2 [Homo sapiens]                          28   9.8  

>gi|13376142 nonhomologous end-joining factor 1 [Homo sapiens]
          Length = 299

 Score =  598 bits (1542), Expect = e-171
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKE 60
           MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKE
Sbjct: 1   MEELEQGLLMQPWAWLQLAENSLLAKVFITKQGYALLVSDLQQVWHEQVDTSVVSQRAKE 60

Query: 61  LNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWN 120
           LNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWN
Sbjct: 61  LNKRLTAPPAAFLCHLDNLLRPLLKDAAHPSEATFSCDCVADALILRVRSELSGLPFYWN 120

Query: 121 FHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLK 180
           FHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLK
Sbjct: 121 FHCMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLK 180

Query: 181 TEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHT 240
           TEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHT
Sbjct: 181 TEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHT 240

Query: 241 SNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS 299
           SNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS
Sbjct: 241 SNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKPRGLFS 299


>gi|237681119 breast cancer 1, early onset isoform 2 [Homo sapiens]
          Length = 1884

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 17/107 (15%)

Query: 157  LHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQD 216
            L  +DLE   Y ESG +L  D  +++P E          ++ PE+  +G       N+  
Sbjct: 1574 LPRQDLEGTPYLESGISLFSDDPESDPSE----------DRAPESARVG-------NIPS 1616

Query: 217  LYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSS 263
               A+   +++V +  Q     HT+++A    ++     +  +L +S
Sbjct: 1617 STSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTAS 1663


>gi|237681125 breast cancer 1, early onset isoform 5 [Homo sapiens]
          Length = 699

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 17/107 (15%)

Query: 157 LHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQD 216
           L  +DLE   Y ESG +L  D  +++P E          ++ PE+  +G       N+  
Sbjct: 449 LPRQDLEGTPYLESGISLFSDDPESDPSE----------DRAPESARVG-------NIPS 491

Query: 217 LYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSS 263
              A+   +++V +  Q     HT+++A    ++     +  +L +S
Sbjct: 492 STSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTAS 538


>gi|237681123 breast cancer 1, early onset isoform 4 [Homo sapiens]
          Length = 759

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 17/107 (15%)

Query: 157 LHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQD 216
           L  +DLE   Y ESG +L  D  +++P E          ++ PE+  +G       N+  
Sbjct: 449 LPRQDLEGTPYLESGISLFSDDPESDPSE----------DRAPESARVG-------NIPS 491

Query: 217 LYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSS 263
              A+   +++V +  Q     HT+++A    ++     +  +L +S
Sbjct: 492 STSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTAS 538


>gi|237681121 breast cancer 1, early onset isoform 3 [Homo sapiens]
          Length = 1816

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 17/107 (15%)

Query: 157  LHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQD 216
            L  +DLE   Y ESG +L  D  +++P E          ++ PE+  +G       N+  
Sbjct: 1506 LPRQDLEGTPYLESGISLFSDDPESDPSE----------DRAPESARVG-------NIPS 1548

Query: 217  LYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSS 263
               A+   +++V +  Q     HT+++A    ++     +  +L +S
Sbjct: 1549 STSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTAS 1595


>gi|6552299 breast cancer 1, early onset isoform 1 [Homo sapiens]
          Length = 1863

 Score = 34.7 bits (78), Expect = 0.10
 Identities = 24/107 (22%), Positives = 47/107 (43%), Gaps = 17/107 (15%)

Query: 157  LHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQD 216
            L  +DLE   Y ESG +L  D  +++P E          ++ PE+  +G       N+  
Sbjct: 1553 LPRQDLEGTPYLESGISLFSDDPESDPSE----------DRAPESARVG-------NIPS 1595

Query: 217  LYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSS 263
               A+   +++V +  Q     HT+++A    ++     +  +L +S
Sbjct: 1596 STSALKVPQLKVAESAQSPAAAHTTDTAGYNAMEESVSREKPELTAS 1642


>gi|119943102 CREB binding protein isoform b [Homo sapiens]
          Length = 2404

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 6/55 (10%)

Query: 226 VQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGP 280
           VQ G   Q  G P+++N ASL  +    ++Q +   SSAP+L    K++  TSGP
Sbjct: 95  VQQGLGGQAQGQPNSANMASLSAMGKSPLSQGD---SSAPSL---PKQAASTSGP 143


>gi|119943104 CREB binding protein isoform a [Homo sapiens]
          Length = 2442

 Score = 32.7 bits (73), Expect = 0.40
 Identities = 21/55 (38%), Positives = 31/55 (56%), Gaps = 6/55 (10%)

Query: 226 VQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGP 280
           VQ G   Q  G P+++N ASL  +    ++Q +   SSAP+L    K++  TSGP
Sbjct: 95  VQQGLGGQAQGQPNSANMASLSAMGKSPLSQGD---SSAPSL---PKQAASTSGP 143


>gi|59806363 hypothetical protein LOC9729 [Homo sapiens]
          Length = 694

 Score = 30.8 bits (68), Expect = 1.5
 Identities = 29/107 (27%), Positives = 46/107 (42%), Gaps = 13/107 (12%)

Query: 145 ALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLKTEPFEENSFLEQFMIEKLPEACSI 204
           AL   + ELA +      E+  +QE     IR R      + +SFL++     +P   +I
Sbjct: 163 ALSTALEELAKVSE----ELCSFQEE----IRKRSNHRRMKSDSFLQE-----MPNVTNI 209

Query: 205 GDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDS 251
             G P + N Q +      +E Q  +K+    +   SNS    GID+
Sbjct: 210 PHGDPMINNDQCILPISLEKEKQKNRKNLSCTNVLQSNSTKKCGIDT 256


>gi|49087132 sal-like 2 [Homo sapiens]
          Length = 1007

 Score = 30.0 bits (66), Expect = 2.6
 Identities = 20/50 (40%), Positives = 23/50 (46%), Gaps = 1/50 (2%)

Query: 234 GAGDPHTSNSASL-QGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQ 282
           GA    TS    L + ID Q         S APT SAP   S+ +SGP Q
Sbjct: 583 GASPSETSKLQQLVEKIDRQGAVAVTSAASGAPTTSAPAPSSSASSGPNQ 632


>gi|8922122 elaC homolog 1 [Homo sapiens]
          Length = 363

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 12/76 (15%)

Query: 125 LASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLKTEPF 184
           L+   LV  +++  L+    A QC   EL    H+   +    +E G T++ D       
Sbjct: 109 LSHTELVFHYVVHELV--PTADQCPAEELKEFAHVNRADSPPKEEQGRTILLDS------ 160

Query: 185 EENSFL----EQFMIE 196
           EENS+L    EQF+++
Sbjct: 161 EENSYLLFDDEQFVVK 176


>gi|157388975 coiled-coil domain containing 99 [Homo sapiens]
          Length = 605

 Score = 29.6 bits (65), Expect = 3.4
 Identities = 33/164 (20%), Positives = 69/164 (42%), Gaps = 8/164 (4%)

Query: 123 CMLASPSLVSQHLIRPLMGMSLALQCQVRELATLLHMKDLEIQDYQESGATLIRDRLKTE 182
           C      ++S+ +   +    LALQ ++ E+ ++      E+ + Q     L  + L T 
Sbjct: 143 CKSEELRVMSERVQESMSSEMLALQIELTEMESMKTTLKEEVNELQYRQEQL--ELLITN 200

Query: 183 PFEENSFLEQFMIEKLPEACSIGDGKPFVMNLQDLYMAVTTQEVQVGQKHQGAGDPHTSN 242
              +   L++   E+  EA S      +   L+   +A    +VQ+ Q  Q A DP++  
Sbjct: 201 LMRQVDRLKEEKEEREKEAVS------YYNALEKARVANQDLQVQLDQALQQALDPNSKG 254

Query: 243 SASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQL 286
           ++    ++ +      QL+S      + +K++      +QR +L
Sbjct: 255 NSLFAEVEDRRAAMERQLISMKVKYQSLKKQNVFNREQMQRMKL 298


>gi|156938343 talin 2 [Homo sapiens]
          Length = 2542

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 27/105 (25%), Positives = 40/105 (38%), Gaps = 23/105 (21%)

Query: 176 RDRLKTEPFEENSFLEQFMIEK---------------------LPEACSIGDGKPFVMNL 214
           +DR   E  EE++ LE+ +  K                     LP     G   P   N+
Sbjct: 409 KDRFGLEGDEESTMLEESVSPKKSTILQQQFNRTGKAEHGSVALPAVMRSGSSGPETFNV 468

Query: 215 QDLYMAVTTQEVQVGQKHQGAGDPHTSNSASLQGIDSQCVNQPEQ 259
               M    Q+V VGQ H+G   P TS   +L G  +  ++  +Q
Sbjct: 469 GS--MPSPQQQVMVGQMHRGHMPPLTSAQQALMGTINTSMHAVQQ 511


>gi|51593088 neuroligin 3 [Homo sapiens]
          Length = 828

 Score = 29.3 bits (64), Expect = 4.4
 Identities = 18/52 (34%), Positives = 28/52 (53%), Gaps = 5/52 (9%)

Query: 46  HEQVDTSVVSQRAKELNKRLTAPPA--AFLCHLDNLLRPLLKDAAHPSEATF 95
           H+ V+ SVV+    +L+ R  +P    AF  H  +L++P   DAAH  E  +
Sbjct: 461 HQWVEPSVVTA---DLHARYGSPTYFYAFYHHCQSLMKPAWSDAAHGDEVPY 509


>gi|61966703 NHS-like 2 [Homo sapiens]
          Length = 709

 Score = 28.5 bits (62), Expect = 7.5
 Identities = 12/38 (31%), Positives = 22/38 (57%)

Query: 257 PEQLVSSAPTLSAPEKESTGTSGPLQRPQLSKVKRKKP 294
           PE+   ++PTL+ P + S   + PL +   + V++ KP
Sbjct: 526 PEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKP 563


>gi|27734799 REST corepressor 2 [Homo sapiens]
          Length = 523

 Score = 28.1 bits (61), Expect = 9.8
 Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)

Query: 235 AGDPHTSNSASLQGIDSQCVNQPEQLVSSAPTLSAPEKESTGTSGPLQRPQ 285
           +G P  +N  +L+G+DSQ ++   Q+ S   T S+  +   G   PL+ P+
Sbjct: 274 SGSPDLAN-LTLRGLDSQLISLKRQVQSMKQTNSSLRQALEGGIDPLRPPE 323


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.131    0.387 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,459,384
Number of Sequences: 37866
Number of extensions: 499887
Number of successful extensions: 1435
Number of sequences better than 10.0: 16
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 1428
Number of HSP's gapped (non-prelim): 18
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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