Guide to the Human Genome
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Search of human proteins with 4826724

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826724 zygin 1 isoform 1 [Homo sapiens]
         (392 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826724 zygin 1 isoform 1 [Homo sapiens]                           780   0.0  
gi|110349756 zygin 2 isoform 2 [Homo sapiens]                         314   8e-86
gi|110349754 zygin 2 isoform 1 [Homo sapiens]                         260   1e-69
gi|12025680 zygin 1 isoform 2 [Homo sapiens]                          214   1e-55
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    52   7e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    51   2e-06
gi|221219020 NYD-SP11 protein [Homo sapiens]                           50   4e-06
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    49   1e-05
gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo sap...    49   1e-05
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]         46   5e-05
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]         46   5e-05
gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]         46   5e-05
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]         46   5e-05
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]         46   5e-05
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]         46   5e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     46   5e-05
gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo sap...    46   7e-05
gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]    46   7e-05
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    46   7e-05
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    46   7e-05
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ...    46   7e-05
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ...    46   7e-05
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    45   9e-05
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    45   9e-05
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             45   1e-04
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    44   2e-04
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    44   3e-04
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               44   3e-04
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    43   4e-04
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    43   4e-04

>gi|4826724 zygin 1 isoform 1 [Homo sapiens]
          Length = 392

 Score =  780 bits (2013), Expect = 0.0
 Identities = 392/392 (100%), Positives = 392/392 (100%)

Query: 1   MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME 60
           MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME
Sbjct: 1   MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME 60

Query: 61  DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED 120
           DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED
Sbjct: 61  DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED 120

Query: 121 WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD 180
           WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD
Sbjct: 121 WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD 180

Query: 181 PEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVE 240
           PEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVE
Sbjct: 181 PEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVE 240

Query: 241 GAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQ 300
           GAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQ
Sbjct: 241 GAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQ 300

Query: 301 SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDL 360
           SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDL
Sbjct: 301 SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDL 360

Query: 361 QMLTNILFAMKEDNEKVPTLLTDYILKVLCPT 392
           QMLTNILFAMKEDNEKVPTLLTDYILKVLCPT
Sbjct: 361 QMLTNILFAMKEDNEKVPTLLTDYILKVLCPT 392


>gi|110349756 zygin 2 isoform 2 [Homo sapiens]
          Length = 380

 Score =  314 bits (805), Expect = 8e-86
 Identities = 180/339 (53%), Positives = 234/339 (69%), Gaps = 26/339 (7%)

Query: 67  DEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPN- 125
           +EKL++CFR  +   E   P +  ++   E   LQ +E+W+ALTDNY   +  DW+  + 
Sbjct: 55  EEKLSLCFRPSDPGAE---PPRTAVRPITERSLLQGDEIWNALTDNYGNVMPVDWKSSHT 111

Query: 126 --IEALNGNCS----------DTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEE 173
             +  L  N S          DT   E+  E+ +  S   S +N+EPL TADQVIEEIEE
Sbjct: 112 RTLHLLTLNLSEKGVSDSLLFDTSDDEELREQLDMHSIIVSCVNDEPLFTADQVIEEIEE 171

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELT 233
           MMQ SPDPE++E          T S   S+L QE+Q L ++   ++  E ++ +S SEL 
Sbjct: 172 MMQESPDPEDDET--------PTQSDRLSMLSQEIQTLKRSSTGSYE-ERVKRLSVSELN 222

Query: 234 ELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
           E+L+++E AI+++SEELVQQLA RDELEFEKEVKNSFI+VLIEVQNKQKE +E  KK++K
Sbjct: 223 EILEEIETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHKETAKKKKK 282

Query: 294 EKGLSLQSSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKAS 353
            K  S Q+ + E+ + MP  RFSMEGISN++Q+G+R TFG+SG +KQYL TVIPYEKK  
Sbjct: 283 LKNGSSQNGKNERSH-MPGTRFSMEGISNVIQNGLRHTFGNSGGEKQYLTTVIPYEKKNG 341

Query: 354 PPSVEDLQMLTNILFAMKEDNEKVPTLLTDYILKVLCPT 392
           PPSVEDLQ+LT IL AMKED+EKVP+LLTDYILKVLCPT
Sbjct: 342 PPSVEDLQILTKILRAMKEDSEKVPSLLTDYILKVLCPT 380


>gi|110349754 zygin 2 isoform 1 [Homo sapiens]
          Length = 353

 Score =  260 bits (665), Expect = 1e-69
 Identities = 163/339 (48%), Positives = 211/339 (62%), Gaps = 53/339 (15%)

Query: 67  DEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPN- 125
           +EKL++CFR  +   E   P +  ++   E   LQ +E+W+ALTDNY   +  DW+  + 
Sbjct: 55  EEKLSLCFRPSDPGAE---PPRTAVRPITERSLLQGDEIWNALTDNYGNVMPVDWKSSHT 111

Query: 126 --IEALNGNCS----------DTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEE 173
             +  L  N S          DT   E+  E+ +  S   S +N+EPL TADQVIEEIEE
Sbjct: 112 RTLHLLTLNLSEKGVSDSLLFDTSDDEELREQLDMHSIIVSCVNDEPLFTADQVIEEIEE 171

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELT 233
           MMQ SPDPE++E          T S   S+L QE+Q L ++   ++  E ++ +S SEL 
Sbjct: 172 MMQESPDPEDDET--------PTQSDRLSMLSQEIQTLKRSSTGSYE-ERVKRLSVSELN 222

Query: 234 ELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
           E+L+++E AI+++SEELVQQLA RDELEFEKEVKNSFI+VLIEVQNKQKE +E  KK++K
Sbjct: 223 EILEEIETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHKETAKKKKK 282

Query: 294 EKGLSLQSSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKAS 353
            K  S Q+ + E+ + MP                        GT   YL TVIPYEKK  
Sbjct: 283 LKNGSSQNGKNER-SHMP------------------------GT---YLTTVIPYEKKNG 314

Query: 354 PPSVEDLQMLTNILFAMKEDNEKVPTLLTDYILKVLCPT 392
           PPSVEDLQ+LT IL AMKED+EKVP+LLTDYILKVLCPT
Sbjct: 315 PPSVEDLQILTKILRAMKEDSEKVPSLLTDYILKVLCPT 353


>gi|12025680 zygin 1 isoform 2 [Homo sapiens]
          Length = 104

 Score =  214 bits (545), Expect = 1e-55
 Identities = 104/104 (100%), Positives = 104/104 (100%)

Query: 1   MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME 60
           MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME
Sbjct: 1   MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME 60

Query: 61  DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEE 104
           DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEE
Sbjct: 61  DLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEE 104


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 69/282 (24%), Positives = 120/282 (42%), Gaps = 44/282 (15%)

Query: 39  EDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEE 98
           E+  + E E    +       E+ + E +EK+    +    + E    +  Q +I+EEE+
Sbjct: 401 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK---IHEQEKIREEEK 457

Query: 99  TLQDEEVWDALTDNYIPSLSEDWR--------------DPNIEALNGNCSDTEIHEKEEE 144
             + EE+W    +  I    E WR              +  +        D E   +E+E
Sbjct: 458 RQEQEEMWRQ--EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE 515

Query: 145 EFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVL 204
           E   + E      EE +   ++ I E EEMMQ     E+EE++ E+E   E   + + + 
Sbjct: 516 EKMWRQEEKIREQEEKIREQEEKIREQEEMMQ-----EQEEKMGEQE---EKMQEQEKMR 567

Query: 205 LQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEK 264
            QE +   Q        E +R     E  E + + E  IR+  EE++Q+   ++E  +E+
Sbjct: 568 RQEEKIREQEEKIREQKEKIR-----EQEEKIWEQEEKIRE-QEEMMQE---QEEKMWEQ 618

Query: 265 EVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEK 306
           E K      + E + K +EQ E  K RR+E+ +  Q  R+ +
Sbjct: 619 EEK------MCEQEEKMQEQEE--KMRRQEEKMWEQEVRLRQ 652



 Score = 35.4 bits (80), Expect = 0.089
 Identities = 54/291 (18%), Positives = 117/291 (40%), Gaps = 51/291 (17%)

Query: 60  EDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDA----------- 108
           E+ + E++EK+         + E +   + +++ QEE+   Q+E +W+            
Sbjct: 306 EEKIQEWEEKIQ-------EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 358

Query: 109 -LTDNYIPSLSE-DW-RDPNIEALNGNCSDTE-IHEKE----------EEEFNEKSENDS 154
              +  +  L E  W ++  I  L     + E I E+E          E+E  ++ E   
Sbjct: 359 WEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 418

Query: 155 GINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQ--------------- 199
              EE +   ++ I E E+ M    +   E+E + EE+  +   +               
Sbjct: 419 WRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 478

Query: 200 ADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQV---EGAIRDFSEELVQQLAR 256
                + E + + +     W  E   H    ++ E  +++   E  IR+  E++ +Q  +
Sbjct: 479 RQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEK 538

Query: 257 -RDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEK 306
            R++ E  +E +        ++Q ++K +R+  K R +E+ +  Q  +I +
Sbjct: 539 IREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE 589



 Score = 28.9 bits (63), Expect = 8.4
 Identities = 38/185 (20%), Positives = 77/185 (41%), Gaps = 25/185 (13%)

Query: 60  EDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQ-IQEEEETLQDEEVWDALTDNYIPSLS 118
           E+ + E +EK+   +R      E    ++ Q + I+E+EE +Q++E      +  +    
Sbjct: 508 EEKIREQEEKM---WRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQE 564

Query: 119 EDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNS 178
           +  R            + E   +E++E   + E      EE +   +++++E EE M   
Sbjct: 565 KMRRQEE------KIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW-- 616

Query: 179 PDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQ 238
              E+EE++ E+E+  +   Q + +  QE           W  E        ++ E  + 
Sbjct: 617 ---EQEEKMCEQEE--KMQEQEEKMRRQE--------EKMWEQEVRLRQQEEKMQEHQEH 663

Query: 239 VEGAI 243
           +E AI
Sbjct: 664 LEAAI 668


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 56/243 (23%), Positives = 109/243 (44%), Gaps = 20/243 (8%)

Query: 60  EDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSE 119
           E+ + E +EK+         + E +   +  +  +EE+   Q+E +W+   +  I  L E
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWE--KEEKIRELEE 351

Query: 120 DWRDPNIEALNGNCSDTEIHEK-EEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNS 178
              +   E +       +  EK  E+E  ++ E      EE +   ++ I E EEMMQ  
Sbjct: 352 KMHEQ--EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQ 409

Query: 179 PDP--EEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSG--SELTE 234
            +   E+EE++ E+E+  E   Q + +  QE +   Q        E +R       E  E
Sbjct: 410 EEKMGEQEEKMWEQEE--EMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 467

Query: 235 LLDQVEGAIRDFSEELVQQ---LARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKR 291
            + + EG + +   ++ +Q   + R++E   E+E K      + E + K +EQ E+M+++
Sbjct: 468 KMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKK------IREQEEKIREQEEMMQEQ 521

Query: 292 RKE 294
            ++
Sbjct: 522 EEK 524



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 54/227 (23%), Positives = 95/227 (41%), Gaps = 28/227 (12%)

Query: 82  ENLAPVKNQLQIQEEEETL-------QDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCS 134
           + L  V  +LQ Q EE  L       Q+E++W          + E  R+  I+       
Sbjct: 260 KELQSVSAKLQAQVEENELWNRLNQQQEEKMW-----RQEEKIQE--REEKIQEQEEKIR 312

Query: 135 DTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGG 194
           + E   + +EE   + E      EE +   ++ I E+EE M       E+EE  +EE   
Sbjct: 313 EQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE--- 369

Query: 195 ETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSG--SELTELLDQVEGAIRDFSEELVQ 252
           E   + +    QE +   Q        E +R       E  E + + E  + +  EE+ +
Sbjct: 370 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQE 429

Query: 253 Q---LARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKG 296
           Q   + R++E   E+E K      + E + K +EQ E+M+++ ++ G
Sbjct: 430 QEEKMRRQEEKIREQEKK------IREQEEKIREQEEMMQEQEEKMG 470



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 57/254 (22%), Positives = 108/254 (42%), Gaps = 41/254 (16%)

Query: 60  EDLVNEFDEKLNVC--FRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSL 117
           E+ + E +EK++     R    K +    ++ Q + QE+E  +  +E      +  I   
Sbjct: 343 EEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQ 402

Query: 118 SE--DWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMM 175
            E    ++  +        + E   +E+EE   + E      E+ +   ++ I E EEMM
Sbjct: 403 EEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462

Query: 176 QNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTEL 235
           Q      E+EE + E++G     +A    +QE +            E +R        E 
Sbjct: 463 Q------EQEEKMGEQEGKMCEQEAK---MQEQE------------EKMRRQE-----EK 496

Query: 236 LDQVEGAIRDFSEELVQQ---LARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRR 292
           + + E  IR+  E++ +Q   +  ++E  +E+E K      + E + K +EQ E  K RR
Sbjct: 497 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK------MCEQEEKMQEQEE--KMRR 548

Query: 293 KEKGLSLQSSRIEK 306
           +E+ +  Q  R+ +
Sbjct: 549 QEEKMREQEVRLRQ 562



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 28/138 (20%), Positives = 63/138 (45%), Gaps = 2/138 (1%)

Query: 57  KSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPS 116
           +  E+++ E +EK+         + E +   + +++ QEE+   Q++++ +         
Sbjct: 400 REQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQE 459

Query: 117 LSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQ 176
                ++  +    G   + E   +E+EE   + E      E+ +   ++ I E EEMMQ
Sbjct: 460 EMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ 519

Query: 177 NSPDP--EEEEEVLEEED 192
              +   E+EE++ E+E+
Sbjct: 520 EQEEKMWEQEEKMCEQEE 537


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 66/259 (25%), Positives = 107/259 (41%), Gaps = 20/259 (7%)

Query: 48   NFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWD 107
            +FS +       E  +     KL    R    K E +   +++L  +  E  L DEE   
Sbjct: 2124 DFSEKRSELTKDEKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGG 2183

Query: 108  ALTDNYIPSLSEDWRDPNIEALNGNCS----DTEIHEKEEEE-FNEKSEN--DSGINEEP 160
               +  IP L   WR    EA  G+       +++ E E EE F+E+ E+  D    +E 
Sbjct: 2184 IEEEEVIPFLKRRWRKRK-EAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQES 2242

Query: 161  LLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWS 220
            L + ++   E EE  +     EEEEE  EEE+G E   + +    +E +   +       
Sbjct: 2243 LSSEEEEEREEEEEREEEEVREEEEERKEEEEGEEKQVEKEE---EEKKKKKKEKKKEEV 2299

Query: 221  YEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNK 280
             E  +     E  E++ + E       EE  +  +  +E++ EKE+         E Q K
Sbjct: 2300 QE--KEEVFEEKEEIMSEEETESLSDEEEEEESCSLEEEVDREKEILKK------EKQFK 2351

Query: 281  QKEQRELMKKRRKEKGLSL 299
             +EQR     R +E+ LS+
Sbjct: 2352 LQEQRR-KSLRGRERVLSI 2369



 Score = 37.7 bits (86), Expect = 0.018
 Identities = 39/165 (23%), Positives = 70/165 (42%), Gaps = 31/165 (18%)

Query: 47   ENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVW 106
            E FSS++   +S E    E +  L+   +  +  +E     + + + +EEE   ++EE  
Sbjct: 2211 EKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEEEREEEEVREEEEERK 2270

Query: 107  DALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQ 166
            +           E+  +  +             EKEEEE  +K +      +E +   ++
Sbjct: 2271 E----------EEEGEEKQV-------------EKEEEEKKKKKKEK---KKEEVQEKEE 2304

Query: 167  VIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQAL 211
            V EE EE+M      EEE E L +E+  E S   +  + +E + L
Sbjct: 2305 VFEEKEEIMS-----EEETESLSDEEEEEESCSLEEEVDREKEIL 2344



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 62/278 (22%), Positives = 116/278 (41%), Gaps = 35/278 (12%)

Query: 60   EDLVNEFDEKLNVCFRNYNAKTENLAPVKN-QLQIQEEEETLQDEEVW-------DALTD 111
            E+++ E D+KL   +  +    EN+   K+ + Q ++EEE   +EEV          +T+
Sbjct: 1507 EEMLQE-DKKLK--WEEWKQVWENMLSSKSKEQQYKDEEEVTLEEEVSREGEEKEQQVTE 1563

Query: 112  NYIPSLSEDWRDPNIEALNGNCSDTEIHEK----EEEEFNEKSENDSGINEEPLLTAD-Q 166
                 + E+ +   I             E+    +EEE   + E      E  L  A  +
Sbjct: 1564 EQ-RHIQEEHKWARIHRKRARAEKKRAQEERKLAQEEEKLAQEERQLAQEERKLAQAYVK 1622

Query: 167  VIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRH 226
            + ++  EM Q      ++EE L +   GE  SQ    L Q+ + L + +      E    
Sbjct: 1623 ITQDDREMAQAEGKFAQKEETLAQR--GEKLSQEAEKLAQKRKKLAKKWEKVAREEEKLA 1680

Query: 227  MSGSELTEL----------LDQVEGAIRDFSEELVQQLAR----RDELEFEKEVKNSFIT 272
              G +L E+          L Q E  +    +EL Q+L       +EL +++E  N    
Sbjct: 1681 KKGGKLAEVKNILAQKVEELPQREQNLDWQEKELAQELEELEWDMEELSWKEEELNQEEG 1740

Query: 273  VLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQM 310
             L+E + K  E+ E +  +R++  LS + +++ +  ++
Sbjct: 1741 KLVEEKKKLAEEEEALAWQREK--LSEEETKLAQEEEL 1776


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 58/295 (19%), Positives = 123/295 (41%), Gaps = 31/295 (10%)

Query: 21  EDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAK 80
           E  +E+ + +      H ++    + E    +    +  E+ V   +EK+         +
Sbjct: 470 EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQ 529

Query: 81  TENLAPVKNQLQIQEE-----EETLQDEEVWDALTDNYIPSLSEDWR-DPNIEALNGNCS 134
            E +   + +++ QEE     E+  + E++W+   +       + WR +  I        
Sbjct: 530 EEKMWRQEEKIREQEEMWREEEKMHEQEKIWEE--EKRQEQEDKMWRQEEKIREQEEKVW 587

Query: 135 DTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGG 194
             E   +E+EE  ++ E      EE +   ++ I+E EE ++   +   E+E + +E   
Sbjct: 588 RQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEE 647

Query: 195 ETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQ- 253
           +   Q + +  QE + + +     W  E           E + + E  IR+  E++ +Q 
Sbjct: 648 KMGEQEEKMCEQE-EKMQEQEETMWRQE-----------EKIREQEKKIREQEEKIREQE 695

Query: 254 --LARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEK 306
             +  ++E  +E+E K      + E + K +EQ E  K RR+E+ +  Q  R+ +
Sbjct: 696 EMMQEQEEKMWEQEEK------MCEQEEKMQEQEE--KMRRQEEKMWEQEVRLRQ 742



 Score = 37.0 bits (84), Expect = 0.031
 Identities = 44/235 (18%), Positives = 92/235 (39%), Gaps = 44/235 (18%)

Query: 60  EDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSE 119
           E+ + E++EK+         + E +   + +++ QEE+   Q+E +W+            
Sbjct: 306 EEKIQEWEEKIQ-------EQEEKIREQEEKIREQEEKMRRQEEMMWE------------ 346

Query: 120 DWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSP 179
             ++  +        + E   + +EE   + E      EE +   ++ I E+EE M    
Sbjct: 347 --KEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 404

Query: 180 DPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQV 239
              E+EE  +EE+            ++E +   +     W  E           E + + 
Sbjct: 405 KIREQEEKRQEEE-----------KIREQEKRQEQEAKMWRQE-----------EKIREQ 442

Query: 240 EGAIRDFSEELVQQLARRDELE-FEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
           E  IR+  +++ +Q  +  E E   +E K      +   + K  EQ E+ +++ K
Sbjct: 443 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEK 497



 Score = 33.1 bits (74), Expect = 0.44
 Identities = 52/249 (20%), Positives = 97/249 (38%), Gaps = 28/249 (11%)

Query: 95  EEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDS 154
           E E+ L          D YI  L+++    ++E      +D E+ EK     N K +   
Sbjct: 176 ELEQALSAVATQKKKADRYIEELTKERDALSLELYRNTITDEELKEK-----NAKLQEKL 230

Query: 155 GINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQT 214
            + E         ++E++  ++ +     ++++  E D      Q+ S  LQ      + 
Sbjct: 231 QLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENEL 290

Query: 215 FN--NNWSYEGLRHMSGS--ELTELLDQVEGAIRDFSEELVQQ----------------- 253
           +N  N    E +        E  E + + E  IR+  E++ +Q                 
Sbjct: 291 WNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEK 350

Query: 254 LARRDELEFEKEVK-NSFITVLIEVQNKQKEQRELM-KKRRKEKGLSLQSSRIEKGNQMP 311
           + R++E+ +EKE K      ++ E + K + Q E+M +K  K + L  +    EK  +  
Sbjct: 351 MRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQE 410

Query: 312 LKRFSMEGI 320
            KR   E I
Sbjct: 411 EKRQEEEKI 419



 Score = 32.7 bits (73), Expect = 0.58
 Identities = 52/267 (19%), Positives = 115/267 (43%), Gaps = 33/267 (12%)

Query: 57  KSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEE--------VWDA 108
           +  E+++ E +EK+    R    K      ++ Q + ++EEE ++++E        +W  
Sbjct: 380 RRQEEMMWEKEEKI----RELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 435

Query: 109 LTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVI 168
             +  I    E  R+   +       + +IHE+E+    EK +      +E +   ++ I
Sbjct: 436 --EEKIREQEEKIREQEKKMWR---QEEKIHEQEKIREEEKRQE-----QEEMWRQEEKI 485

Query: 169 EEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGL---R 225
            E EE+ +      E+EE + +++  E   + +  + ++ + + +     W  E     +
Sbjct: 486 HEQEEIWRQKEKMHEQEEKIRKQE--EKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQ 543

Query: 226 HMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLI-EVQNKQKEQ 284
                E  ++ +Q +    +  +E   ++ R++E   E+E K       I E + K++EQ
Sbjct: 544 EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQ 603

Query: 285 RELM-----KKRRKEKGLSLQSSRIEK 306
            E M     K R +E+ +  Q  +I +
Sbjct: 604 EEKMWKQEEKIREQEEKIQEQEEKIRE 630


>gi|82697315 RUN and FYVE domain containing 3 isoform 1 [Homo
           sapiens]
          Length = 620

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 68/314 (21%), Positives = 129/314 (41%), Gaps = 44/314 (14%)

Query: 37  HLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAK-----------TENLA 85
           +L+D + S+      +I +    ++ V E +  LN    N  AK           TE LA
Sbjct: 241 YLKDGNSSKGTEGDGQITAILDQKNYVEELNRHLNATVNNLQAKVDALEKSNTKLTEELA 300

Query: 86  PVKNQL-QIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEE 144
              N++  +QEE E +++E        +YI   +      +  A     S+   H KEE 
Sbjct: 301 VANNRIITLQEEMERVKEES-------SYILESNRKGPKQDRTAEGQALSEARKHLKEET 353

Query: 145 EFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVL 204
           +     E +     E  ++  Q +E   +M+        E++V E++D   +  Q     
Sbjct: 354 QLRLDVEKEL----EMQISMRQEMELAMKML--------EKDVCEKQDALVSLRQQ---- 397

Query: 205 LQEMQALTQ--TFNNNWSYEGLRHMS--GSELTELLDQVEGAIRDFSEELVQ-----QLA 255
           L +++AL     F    S  G++  S   S L E  +Q+   I+   + L Q     Q A
Sbjct: 398 LDDLRALKHELAFKLQSSDLGVKQKSELNSRLEEKTNQMAATIKQLEQRLRQAERSRQSA 457

Query: 256 RRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRF 315
             D   F+++  +   ++ +EV+   +++ +L  + ++EK   LQ+ R   G        
Sbjct: 458 ELDNRLFKQDFGDKINSLQLEVEELTRQRNQLELELKQEKERRLQNDRSIPGRGSQKSES 517

Query: 316 SMEGISNILQSGIR 329
            M+G   + +  ++
Sbjct: 518 KMDGKHKMQEENVK 531


>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
          Length = 983

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 77/402 (19%), Positives = 169/402 (42%), Gaps = 49/402 (12%)

Query: 10  EEFEDLRPS-CSE-DPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFD 67
           EE+E+++ S CS  +   K + F        ++  +   +   S++    S  D   +  
Sbjct: 577 EEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS--DEAEDMK 634

Query: 68  EKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED--WRDPN 125
           E +N      N +   L+ +  + Q + E+   +  +  + +T  YI     +   +  N
Sbjct: 635 EAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAEYIHKAEHEKLMQLTN 692

Query: 126 IEALNGNCSDTEIHEKEEEEFNE----------KSENDSGINE--EPLLTADQVIEEIEE 173
           +       + +E+  +  +  NE          + EN   I E  + + T     +E+EE
Sbjct: 693 VSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE 752

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELT 233
            + N  +    +EV          ++ +  LL+E  A+T       SYE L+    SE++
Sbjct: 753 KISNLKEHLASKEV--------EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 804

Query: 234 ELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
            L  +++ ++++  +   + +  R E+   K  K +  T+L   ++K++E  EL++K ++
Sbjct: 805 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLL---KSKEQEVNELLQKFQQ 861

Query: 294 E-------KGLSLQSSRIEKGNQMPLKRFSME--GISNILQSGIRQTFGSSGTDKQYLNT 344
                   K  +  SS++E+     +   S E   +   L S  + ++ +S + +Q    
Sbjct: 862 AQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQ---- 917

Query: 345 VIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYIL 386
               + +A    V+ LQ   N L   K+ +++V ++   ++L
Sbjct: 918 --SQQLEALQQQVKQLQ---NQLAECKKQHQEVISVYRMHLL 954


>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
          Length = 972

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 77/402 (19%), Positives = 169/402 (42%), Gaps = 49/402 (12%)

Query: 10  EEFEDLRPS-CSE-DPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFD 67
           EE+E+++ S CS  +   K + F        ++  +   +   S++    S  D   +  
Sbjct: 566 EEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS--DEAEDMK 623

Query: 68  EKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED--WRDPN 125
           E +N      N +   L+ +  + Q + E+   +  +  + +T  YI     +   +  N
Sbjct: 624 EAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAEYIHKAEHEKLMQLTN 681

Query: 126 IEALNGNCSDTEIHEKEEEEFNE----------KSENDSGINE--EPLLTADQVIEEIEE 173
           +       + +E+  +  +  NE          + EN   I E  + + T     +E+EE
Sbjct: 682 VSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE 741

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELT 233
            + N  +    +EV          ++ +  LL+E  A+T       SYE L+    SE++
Sbjct: 742 KISNLKEHLASKEV--------EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 793

Query: 234 ELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
            L  +++ ++++  +   + +  R E+   K  K +  T+L   ++K++E  EL++K ++
Sbjct: 794 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLL---KSKEQEVNELLQKFQQ 850

Query: 294 E-------KGLSLQSSRIEKGNQMPLKRFSME--GISNILQSGIRQTFGSSGTDKQYLNT 344
                   K  +  SS++E+     +   S E   +   L S  + ++ +S + +Q    
Sbjct: 851 AQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQ---- 906

Query: 345 VIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYIL 386
               + +A    V+ LQ   N L   K+ +++V ++   ++L
Sbjct: 907 --SQQLEALQQQVKQLQ---NQLAECKKQHQEVISVYRMHLL 943


>gi|224809474 retinoic acid induced 14 isoform b [Homo sapiens]
          Length = 951

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 77/402 (19%), Positives = 169/402 (42%), Gaps = 49/402 (12%)

Query: 10  EEFEDLRPS-CSE-DPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFD 67
           EE+E+++ S CS  +   K + F        ++  +   +   S++    S  D   +  
Sbjct: 545 EEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS--DEAEDMK 602

Query: 68  EKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED--WRDPN 125
           E +N      N +   L+ +  + Q + E+   +  +  + +T  YI     +   +  N
Sbjct: 603 EAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAEYIHKAEHEKLMQLTN 660

Query: 126 IEALNGNCSDTEIHEKEEEEFNE----------KSENDSGINE--EPLLTADQVIEEIEE 173
           +       + +E+  +  +  NE          + EN   I E  + + T     +E+EE
Sbjct: 661 VSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE 720

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELT 233
            + N  +    +EV          ++ +  LL+E  A+T       SYE L+    SE++
Sbjct: 721 KISNLKEHLASKEV--------EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 772

Query: 234 ELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
            L  +++ ++++  +   + +  R E+   K  K +  T+L   ++K++E  EL++K ++
Sbjct: 773 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLL---KSKEQEVNELLQKFQQ 829

Query: 294 E-------KGLSLQSSRIEKGNQMPLKRFSME--GISNILQSGIRQTFGSSGTDKQYLNT 344
                   K  +  SS++E+     +   S E   +   L S  + ++ +S + +Q    
Sbjct: 830 AQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQ---- 885

Query: 345 VIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYIL 386
               + +A    V+ LQ   N L   K+ +++V ++   ++L
Sbjct: 886 --SQQLEALQQQVKQLQ---NQLAECKKQHQEVISVYRMHLL 922


>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 77/402 (19%), Positives = 169/402 (42%), Gaps = 49/402 (12%)

Query: 10  EEFEDLRPS-CSE-DPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFD 67
           EE+E+++ S CS  +   K + F        ++  +   +   S++    S  D   +  
Sbjct: 574 EEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS--DEAEDMK 631

Query: 68  EKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED--WRDPN 125
           E +N      N +   L+ +  + Q + E+   +  +  + +T  YI     +   +  N
Sbjct: 632 EAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAEYIHKAEHEKLMQLTN 689

Query: 126 IEALNGNCSDTEIHEKEEEEFNE----------KSENDSGINE--EPLLTADQVIEEIEE 173
           +       + +E+  +  +  NE          + EN   I E  + + T     +E+EE
Sbjct: 690 VSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE 749

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELT 233
            + N  +    +EV          ++ +  LL+E  A+T       SYE L+    SE++
Sbjct: 750 KISNLKEHLASKEV--------EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 801

Query: 234 ELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
            L  +++ ++++  +   + +  R E+   K  K +  T+L   ++K++E  EL++K ++
Sbjct: 802 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLL---KSKEQEVNELLQKFQQ 858

Query: 294 E-------KGLSLQSSRIEKGNQMPLKRFSME--GISNILQSGIRQTFGSSGTDKQYLNT 344
                   K  +  SS++E+     +   S E   +   L S  + ++ +S + +Q    
Sbjct: 859 AQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQ---- 914

Query: 345 VIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYIL 386
               + +A    V+ LQ   N L   K+ +++V ++   ++L
Sbjct: 915 --SQQLEALQQQVKQLQ---NQLAECKKQHQEVISVYRMHLL 951


>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 77/402 (19%), Positives = 169/402 (42%), Gaps = 49/402 (12%)

Query: 10  EEFEDLRPS-CSE-DPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFD 67
           EE+E+++ S CS  +   K + F        ++  +   +   S++    S  D   +  
Sbjct: 574 EEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS--DEAEDMK 631

Query: 68  EKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED--WRDPN 125
           E +N      N +   L+ +  + Q + E+   +  +  + +T  YI     +   +  N
Sbjct: 632 EAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAEYIHKAEHEKLMQLTN 689

Query: 126 IEALNGNCSDTEIHEKEEEEFNE----------KSENDSGINE--EPLLTADQVIEEIEE 173
           +       + +E+  +  +  NE          + EN   I E  + + T     +E+EE
Sbjct: 690 VSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE 749

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELT 233
            + N  +    +EV          ++ +  LL+E  A+T       SYE L+    SE++
Sbjct: 750 KISNLKEHLASKEV--------EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 801

Query: 234 ELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
            L  +++ ++++  +   + +  R E+   K  K +  T+L   ++K++E  EL++K ++
Sbjct: 802 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLL---KSKEQEVNELLQKFQQ 858

Query: 294 E-------KGLSLQSSRIEKGNQMPLKRFSME--GISNILQSGIRQTFGSSGTDKQYLNT 344
                   K  +  SS++E+     +   S E   +   L S  + ++ +S + +Q    
Sbjct: 859 AQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQ---- 914

Query: 345 VIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYIL 386
               + +A    V+ LQ   N L   K+ +++V ++   ++L
Sbjct: 915 --SQQLEALQQQVKQLQ---NQLAECKKQHQEVISVYRMHLL 951


>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
          Length = 980

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 77/402 (19%), Positives = 169/402 (42%), Gaps = 49/402 (12%)

Query: 10  EEFEDLRPS-CSE-DPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFD 67
           EE+E+++ S CS  +   K + F        ++  +   +   S++    S  D   +  
Sbjct: 574 EEYEEMKSSYCSVIENMNKEKAFLFEKYQEAQEEIMKLKDTLKSQMTQEAS--DEAEDMK 631

Query: 68  EKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSED--WRDPN 125
           E +N      N +   L+ +  + Q + E+   +  +  + +T  YI     +   +  N
Sbjct: 632 EAMNRMIDELNKQVSELSQLYKEAQAELED--YRKRKSLEDVTAEYIHKAEHEKLMQLTN 689

Query: 126 IEALNGNCSDTEIHEKEEEEFNE----------KSENDSGINE--EPLLTADQVIEEIEE 173
           +       + +E+  +  +  NE          + EN   I E  + + T     +E+EE
Sbjct: 690 VSRAKAEDALSEMKSQYSKVLNELTQLKQLVDAQKENSVSITEHLQVITTLRTAAKEMEE 749

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELT 233
            + N  +    +EV          ++ +  LL+E  A+T       SYE L+    SE++
Sbjct: 750 KISNLKEHLASKEV--------EVAKLEKQLLEEKAAMTDAMVPRSSYEKLQSSLESEVS 801

Query: 234 ELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
            L  +++ ++++  +   + +  R E+   K  K +  T+L   ++K++E  EL++K ++
Sbjct: 802 VLASKLKESVKEKEKVHSEVVQIRSEVSQVKREKENIQTLL---KSKEQEVNELLQKFQQ 858

Query: 294 E-------KGLSLQSSRIEKGNQMPLKRFSME--GISNILQSGIRQTFGSSGTDKQYLNT 344
                   K  +  SS++E+     +   S E   +   L S  + ++ +S + +Q    
Sbjct: 859 AQEELAEMKRYAESSSKLEEDKDKKINEMSKEVTKLKEALNSLSQLSYSTSSSKRQ---- 914

Query: 345 VIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYIL 386
               + +A    V+ LQ   N L   K+ +++V ++   ++L
Sbjct: 915 --SQQLEALQQQVKQLQ---NQLAECKKQHQEVISVYRMHLL 951


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 74/316 (23%), Positives = 139/316 (43%), Gaps = 45/316 (14%)

Query: 46  LENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEV 105
           +E   +E+ S K  +D +  + EKL V  + Y  + E L     +   QE+E  L+D+E+
Sbjct: 609 VEKHKTELESLKHQQDAL--WTEKLQVLKQQYQTEMEKL----REKCEQEKETLLKDKEI 662

Query: 106 WDALTDNYIPSLSE------DWRDPNIEALNGNCSDT-EIHEKEEEEFNE--------KS 150
              +   +I  ++E      D +   +E+L+   S+  +   K EEE +         K 
Sbjct: 663 ---IFQAHIEEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDKMKQ 719

Query: 151 ENDSGINEEP---LLTADQVIEEIEEMMQNSPDPEEE-----EEVLEEEDGGETSSQADS 202
           E ++ ++E+        D +I+E E  +Q +    ++     E +L+E D      QA  
Sbjct: 720 ELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKERDKHLKEHQAHV 779

Query: 203 VLLQ--------EMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQL 254
             L+        E+Q  +   +   SY+   H       E L Q++  + D   E +   
Sbjct: 780 ENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLT 839

Query: 255 ARRDELEFE-KEVKNSFITVLIEVQN-KQKEQRELMKKRRKEKGLS-LQSSRIEKGN--Q 309
            +  E+E + K+V        I+VQ+  Q+ +++  +  +K K L+ +  S++E GN  Q
Sbjct: 840 KQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVYESKLEDGNKEQ 899

Query: 310 MPLKRFSMEGISNILQ 325
              K+  +E  + ILQ
Sbjct: 900 EQTKQILVEKENMILQ 915



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 77/409 (18%), Positives = 162/409 (39%), Gaps = 76/409 (18%)

Query: 45   ELENFSSEIIS-FKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDE 103
            +++  S E IS  + ++D  N+F E        +      +  ++ QL+++ +E   +DE
Sbjct: 1420 KVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLELKSKEAYEKDE 1479

Query: 104  EVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEE---EFNEKSENDSGINEEP 160
            ++ + L +        D ++   + L G   D +   +++E   E   KS+    +  E 
Sbjct: 1480 QI-NLLKEEL------DQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELED 1532

Query: 161  LLTADQV-IEEIEEMMQN---SPDPEEEEEV--------LEEEDGGETSSQADSVLLQEM 208
             +T   + IE + E+++N     D E +E V        L EE         + +L  E 
Sbjct: 1533 HITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLEN 1592

Query: 209  QALTQTFNNNWSYEGLRHM---------------------SGSELTELLDQVEGAIRDFS 247
            Q  +         + L H+                     S ++L EL  + E  I    
Sbjct: 1593 QVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIK 1652

Query: 248  EELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKE--------------QRELMKKRRK 293
            ++L+ Q+  ++E +++K  ++    +  ++Q +++E              Q E +   R 
Sbjct: 1653 KQLLSQMEEKEE-QYKKGTESHLSELNTKLQEREREVHILEEKLKSVESSQSETLIVPRS 1711

Query: 294  EKGLSLQSSRIEKGNQMPLKRFSMEGISNILQSGI---RQTFGSSGTDK----------- 339
             K ++  + + E  +Q  +++   E IS +LQ  +    +     G +K           
Sbjct: 1712 AKNVAAYTEQEEADSQGCVQKTYEEKIS-VLQRNLTEKEKLLQRVGQEKEETVSSHFEMR 1770

Query: 340  -QYLNTVIPYEKKASPPSVEDLQMLTNILFAMKEDNEKVPTLLTDYILK 387
             QY   +I  E  A     ED  M+ ++   ++E N+K   ++  ++ K
Sbjct: 1771 CQYQERLIKLE-HAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEK 1818


>gi|38045898 RAB6-interacting protein 2 isoform epsilon [Homo
           sapiens]
          Length = 1116

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 57/281 (20%), Positives = 121/281 (43%), Gaps = 20/281 (7%)

Query: 40  DPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEET 99
           +  L +    + E  +   M D +   + ++   +++ ++K +  A V   L+I +E E 
Sbjct: 714 ESQLKKAHEAALEARASPEMSDRIQHLEREITR-YKDESSKAQ--AEVDRLLEILKEVEN 770

Query: 100 LQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINE- 158
            ++++      D  I  L    +D N +  N    +    +K  +   E    +  +N+ 
Sbjct: 771 EKNDK------DKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDS 824

Query: 159 -----EPLLTADQVIEEIEEMMQNSPD-PEEEEEVLEEEDGGETSSQAD-SVLLQEMQAL 211
                + L   D  IEE+EE ++ S     E E VL +E+   T+++     LL  M+ +
Sbjct: 825 SQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV 884

Query: 212 TQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFI 271
            Q   +  +       S +E    L  +    R   EE+++   +++ L      K++ I
Sbjct: 885 KQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEM--KQEALLAAISEKDANI 942

Query: 272 TVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPL 312
             L+E+ + +K+ +E +   ++EK   +Q  + +  N+M L
Sbjct: 943 A-LLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 982


>gi|38045896 RAB6-interacting protein 2 isoform delta [Homo sapiens]
          Length = 1088

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 57/281 (20%), Positives = 121/281 (43%), Gaps = 20/281 (7%)

Query: 40  DPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEET 99
           +  L +    + E  +   M D +   + ++   +++ ++K +  A V   L+I +E E 
Sbjct: 686 ESQLKKAHEAALEARASPEMSDRIQHLEREITR-YKDESSKAQ--AEVDRLLEILKEVEN 742

Query: 100 LQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINE- 158
            ++++      D  I  L    +D N +  N    +    +K  +   E    +  +N+ 
Sbjct: 743 EKNDK------DKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDS 796

Query: 159 -----EPLLTADQVIEEIEEMMQNSPD-PEEEEEVLEEEDGGETSSQAD-SVLLQEMQAL 211
                + L   D  IEE+EE ++ S     E E VL +E+   T+++     LL  M+ +
Sbjct: 797 SQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKV 856

Query: 212 TQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFI 271
            Q   +  +       S +E    L  +    R   EE+++   +++ L      K++ I
Sbjct: 857 KQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEM--KQEALLAAISEKDANI 914

Query: 272 TVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPL 312
             L+E+ + +K+ +E +   ++EK   +Q  + +  N+M L
Sbjct: 915 A-LLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKL 954


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 56/275 (20%), Positives = 120/275 (43%), Gaps = 35/275 (12%)

Query: 39  EDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEE 98
           E+    + E    + +  +  E+ +   +EK++        + + +   + +++ QEE+ 
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKI 362

Query: 99  TLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEF----NEKSENDS 154
             Q+E++W    +  I    E  ++   E         E  EK +E+      +  E D 
Sbjct: 363 REQEEKMWRQ--EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420

Query: 155 GINE--EPLLTADQVIEEIEEMMQNSPDP-EEEEEVLEEEDGGETSSQADSVLLQEMQAL 211
            I E  E +   ++ I E+EEMMQ+  +   E EE ++EE+  E   + +  + ++ + +
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE--EKMQEQEEKIQRQEEKI 478

Query: 212 TQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFI 271
            +     W  E           +LL Q E   + + +E  +++ R++E  +E+E K    
Sbjct: 479 QEQEEKTWRQE-----------KLLKQEE---KIWEQE--EKMWRQEEKMWEQEEKMQ-- 520

Query: 272 TVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEK 306
                 + ++K QR+  K R +E  L  Q  ++++
Sbjct: 521 ------EQEEKMQRQEEKMREQEVRLWQQEEKMQE 549



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 33/143 (23%), Positives = 61/143 (42%), Gaps = 17/143 (11%)

Query: 67  DEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNI 126
           +EK+         + E L  V+ ++Q +EEE+  + EE      +       + WR   +
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491

Query: 127 EALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEE 186
                   + +I E+EE+ + +         EE +   ++ ++E EE MQ   +   E+E
Sbjct: 492 LK-----QEEKIWEQEEKMWRQ---------EEKMWEQEEKMQEQEEKMQRQEEKMREQE 537

Query: 187 VLEEEDGGETSSQADSVLLQEMQ 209
           V   +   E   Q   V LQE++
Sbjct: 538 VRLWQQ--EEKMQEQEVRLQELE 558


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
           member 6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 56/275 (20%), Positives = 120/275 (43%), Gaps = 35/275 (12%)

Query: 39  EDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEE 98
           E+    + E    + +  +  E+ +   +EK++        + + +   + +++ QEE+ 
Sbjct: 303 EEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKI 362

Query: 99  TLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEF----NEKSENDS 154
             Q+E++W    +  I    E  ++   E         E  EK +E+      +  E D 
Sbjct: 363 REQEEKMWRQ--EEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDE 420

Query: 155 GINE--EPLLTADQVIEEIEEMMQNSPDP-EEEEEVLEEEDGGETSSQADSVLLQEMQAL 211
            I E  E +   ++ I E+EEMMQ+  +   E EE ++EE+  E   + +  + ++ + +
Sbjct: 421 KIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE--EKMQEQEEKIQRQEEKI 478

Query: 212 TQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFI 271
            +     W  E           +LL Q E   + + +E  +++ R++E  +E+E K    
Sbjct: 479 QEQEEKTWRQE-----------KLLKQEE---KIWEQE--EKMWRQEEKMWEQEEKMQ-- 520

Query: 272 TVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEK 306
                 + ++K QR+  K R +E  L  Q  ++++
Sbjct: 521 ------EQEEKMQRQEEKMREQEVRLWQQEEKMQE 549



 Score = 34.3 bits (77), Expect = 0.20
 Identities = 33/143 (23%), Positives = 61/143 (42%), Gaps = 17/143 (11%)

Query: 67  DEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNI 126
           +EK+         + E L  V+ ++Q +EEE+  + EE      +       + WR   +
Sbjct: 433 EEKIRELEEMMQDQEEKLREVEEKMQ-EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKL 491

Query: 127 EALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEE 186
                   + +I E+EE+ + +         EE +   ++ ++E EE MQ   +   E+E
Sbjct: 492 LK-----QEEKIWEQEEKMWRQ---------EEKMWEQEEKMQEQEEKMQRQEEKMREQE 537

Query: 187 VLEEEDGGETSSQADSVLLQEMQ 209
           V   +   E   Q   V LQE++
Sbjct: 538 VRLWQQ--EEKMQEQEVRLQELE 558


>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
           [Homo sapiens]
          Length = 916

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 58/242 (23%), Positives = 100/242 (41%), Gaps = 28/242 (11%)

Query: 119 EDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNS 178
           ED +    EAL     +  +  KEE     K E      EEP    ++V  +   +   +
Sbjct: 463 EDEKSEMEEALTAITEELAVSMKEE-----KKEAAEEKEEEPEAEEEEVAAKKSPVKATA 517

Query: 179 PDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQ 238
           P+ +EEE   EEE+G E   + D           +   ++ + EG     GS   E  +Q
Sbjct: 518 PEVKEEEGEKEEEEGQEEEEEED-----------EGAKSDQAEEGGSEKEGSSEKEEGEQ 566

Query: 239 VEGAIRDFS--EELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKG 296
            EG     +  EE   +  ++ E + E+      +    +V+  +K +  + K   +EKG
Sbjct: 567 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKG 626

Query: 297 LS-LQSSRIEKGNQMPLKRFSME--GISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKAS 353
            S +  S +E+  + P+ +  +E  G S + +S + +  G S   K       P E+KA 
Sbjct: 627 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK-GKSPVSKS------PVEEKAK 679

Query: 354 PP 355
            P
Sbjct: 680 SP 681


>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
           [Homo sapiens]
          Length = 540

 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 58/242 (23%), Positives = 100/242 (41%), Gaps = 28/242 (11%)

Query: 119 EDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNS 178
           ED +    EAL     +  +  KEE     K E      EEP    ++V  +   +   +
Sbjct: 87  EDEKSEMEEALTAITEELAVSMKEE-----KKEAAEEKEEEPEAEEEEVAAKKSPVKATA 141

Query: 179 PDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQ 238
           P+ +EEE   EEE+G E   + D           +   ++ + EG     GS   E  +Q
Sbjct: 142 PEVKEEEGEKEEEEGQEEEEEED-----------EGAKSDQAEEGGSEKEGSSEKEEGEQ 190

Query: 239 VEGAIRDFS--EELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKG 296
            EG     +  EE   +  ++ E + E+      +    +V+  +K +  + K   +EKG
Sbjct: 191 EEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKG 250

Query: 297 LS-LQSSRIEKGNQMPLKRFSME--GISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKAS 353
            S +  S +E+  + P+ +  +E  G S + +S + +  G S   K       P E+KA 
Sbjct: 251 KSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK-GKSPVSKS------PVEEKAK 303

Query: 354 PP 355
            P
Sbjct: 304 SP 305


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 436

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 47/248 (18%), Positives = 107/248 (43%), Gaps = 24/248 (9%)

Query: 60  EDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSE 119
           E  + E +E++         + E +   + Q++ QEE+   Q+E+V     +  +    E
Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQV--QKQEEQVQKQEE 255

Query: 120 DWRDPNIEALNGNCSDTEIHEKEEEEFNEK----SENDSGINEEPLLTADQVIEEIEEMM 175
             R    +       + ++ E+EE+   +K     E  +G  EE +   ++ + E EE M
Sbjct: 256 QMRKQEEQMRE---QEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQM 312

Query: 176 QNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTEL 235
           +     E+EE++ E+E   E   + +  + ++ + + +     W  E        E  E 
Sbjct: 313 R-----EQEEQMREQE---EQMGKQEEQMWEQKEQMWEQKEQMWKQE----EQMGEQEEQ 360

Query: 236 LDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEK 295
           + + E  +R   E++ +Q    +++  ++E        + E + +  EQ+E M+++ ++ 
Sbjct: 361 MQKQEEQVRKQEEQMRKQ---EEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQM 417

Query: 296 GLSLQSSR 303
           G   +  R
Sbjct: 418 GEQKEQMR 425



 Score = 35.8 bits (81), Expect = 0.068
 Identities = 45/229 (19%), Positives = 98/229 (42%), Gaps = 7/229 (3%)

Query: 92  QIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPN--IEALNGNCSDTEIHEKEEEEFNEK 149
           Q++E+E  ++++E      +  +       R+    +    G   + E    E+E    +
Sbjct: 144 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGE 203

Query: 150 SENDSGINEEPLLTADQVIEEIEEMMQNSPDPE-EEEEVLEEEDGGETSSQADSVLLQEM 208
            E   G  EE +   ++ + E EE M+   +   E+EE +++++  +   Q + +  QE 
Sbjct: 204 QEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQE-EQVQKQEEQMRKQEE 262

Query: 209 QALTQTFNNNWSYEG-LRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVK 267
           Q   Q        E  L+    +E  E   + E  +R+  E++ +Q  +  E E +   +
Sbjct: 263 QMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQ 322

Query: 268 NSFITVLIEVQNKQKEQRELMKKR--RKEKGLSLQSSRIEKGNQMPLKR 314
              +    E   +QKEQ    K++  ++E+ +  Q  +++K  +   K+
Sbjct: 323 EEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQ 371



 Score = 30.0 bits (66), Expect = 3.8
 Identities = 31/179 (17%), Positives = 71/179 (39%), Gaps = 6/179 (3%)

Query: 13  EDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFDEKLNV 72
           E +R    +  E++ Q          E+ +  + E    +    +  E+ + E +E++  
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321

Query: 73  CFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGN 132
                  + E +   K Q+  Q+E+   Q+E++ +   +  +    E  R    +     
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGE--QEEQMQKQEEQVRKQEEQMR--- 376

Query: 133 CSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEE 191
               E   K+EE+  ++ E      E+     +Q+ E+ E+M +      ++EE + E+
Sbjct: 377 -KQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQ 434



 Score = 29.6 bits (65), Expect = 4.9
 Identities = 33/177 (18%), Positives = 68/177 (38%), Gaps = 6/177 (3%)

Query: 10  EEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSMEDLVNEFDEK 69
           E+ E +R    +  ++K Q          E+    + E    +    +  E+ + E +E+
Sbjct: 266 EQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQ 325

Query: 70  LNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEAL 129
           +         + E +   K Q+  QEE+   Q+E++     +  +    E  R    +  
Sbjct: 326 MGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQM--QKQEEQVRKQEEQMRKQEEQMR 383

Query: 130 NGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEE 186
                  E   K+EE+  E+ E      E+     +Q+ E+ E+M +      E++E
Sbjct: 384 ----KQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEEHMGEQKE 436


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 66/285 (23%), Positives = 118/285 (41%), Gaps = 55/285 (19%)

Query: 39  EDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEE 98
           E+  + E E    +       E+ + E +EK+         + E    +  Q +I+EEE+
Sbjct: 462 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEK---IHEQEKIREEEK 518

Query: 99  TLQDEEVWDALTDNYIPSLSEDWR---------------DPNIEALNGNCSDTEIHEKEE 143
             + EE+W    +  I    E WR               +  +        D E   +E+
Sbjct: 519 RQEQEEMWRQ--EEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ 576

Query: 144 EEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDP--EEEEEVLEEEDGGETSSQAD 201
           EE   + E      EE +   ++ I E EEM Q   +   E+EE++ E+E+  +   Q +
Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE--KMQEQEE 634

Query: 202 SVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELE 261
            +  QE              E +R     E  + + + E  IR+  EE++Q+   ++E  
Sbjct: 635 KMRRQE--------------EKIR-----EQEKKIREQEEKIRE-QEEMMQE---QEEKM 671

Query: 262 FEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEK 306
           +E+E K      + E + K +EQ E  K RR+E+ +  Q  R+ +
Sbjct: 672 WEQEEK------MCEQEEKMQEQEE--KMRRQEEKMWEQEVRLRQ 708



 Score = 39.7 bits (91), Expect = 0.005
 Identities = 62/304 (20%), Positives = 121/304 (39%), Gaps = 60/304 (19%)

Query: 60  EDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWD-----ALTDNYI 114
           E+ + E++EK+         + E +   + +++ QEE+   Q+E +W+        +  +
Sbjct: 367 EEKIQEWEEKIQ-------EQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMM 419

Query: 115 PSLSEDWR---------DPNIEALNGNCSDTE-IHEKE----------EEEFNEKSENDS 154
               E  R         +  I  L     + E I E+E          E+E  ++ E   
Sbjct: 420 WEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKM 479

Query: 155 GINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSS----QADSVLLQE--- 207
              EE +   ++ I E EE M    +   E+E + EE+  +       Q + +  QE   
Sbjct: 480 WRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539

Query: 208 ---------MQALTQTFNNNWSYEGLRHMSGSELTELLDQV---EGAIRDFSEELVQQ-- 253
                     + + +     W  E   H    ++ E  ++V   E  IR+  E++ +Q  
Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEE 599

Query: 254 -LARRDELEFEKEVK-NSFITVLIEVQNKQKEQRELMKK-----RRKEKGLSLQSSRIEK 306
            +  ++E+  E+E K       + E + K +EQ E M++     R +EK +  Q  +I +
Sbjct: 600 KIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE 659

Query: 307 GNQM 310
             +M
Sbjct: 660 QEEM 663



 Score = 36.2 bits (82), Expect = 0.052
 Identities = 46/214 (21%), Positives = 82/214 (38%), Gaps = 31/214 (14%)

Query: 89  NQLQIQEEEETLQDEEV---WDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEE-- 143
           N+L  Q+EE+  + EE    W+         + E       +       +  + EKEE  
Sbjct: 353 NRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKM 412

Query: 144 ---EEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQA 200
              EE   + E      EE +   ++ I E+EE M       E+EE  +EE+        
Sbjct: 413 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEE-------- 464

Query: 201 DSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDEL 260
               ++E +   +     W  E           E + + E  IR+  E++ +Q  +  E 
Sbjct: 465 ---KIREQEKRQEQEAKMWRQE-----------EKIREQEEKIREQEEKMWRQEEKIHEQ 510

Query: 261 E-FEKEVKNSFITVLIEVQNKQKEQRELMKKRRK 293
           E   +E K      +   + K +EQ E+ +++ K
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544



 Score = 36.2 bits (82), Expect = 0.052
 Identities = 31/152 (20%), Positives = 68/152 (44%), Gaps = 20/152 (13%)

Query: 92  QIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSE 151
           +I+E+EE ++++E            ++++  +   E     C   E  +++EE+   + E
Sbjct: 593 KIREQEEKIREQE-----------EMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641

Query: 152 NDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQAL 211
                 E+ +   ++ I E EEMMQ     E+EE++ E+E   E   + +  + ++ + +
Sbjct: 642 KIRE-QEKKIREQEEKIREQEEMMQ-----EQEEKMWEQE---EKMCEQEEKMQEQEEKM 692

Query: 212 TQTFNNNWSYEGLRHMSGSELTELLDQVEGAI 243
            +     W  E        ++ E  + +E AI
Sbjct: 693 RRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 51/232 (21%), Positives = 102/232 (43%), Gaps = 25/232 (10%)

Query: 140 EKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQ 199
           E    E +++ E +  I     L   +  E +E + Q     EEE+++L+++   ET SQ
Sbjct: 764 ELRATELSKQLEMEKEIVSSTRLDLQKKSEALESIKQKLTKQEEEKQILKQDF--ETLSQ 821

Query: 200 ADSVLLQEMQALTQTFNNNWSYEGLRHMS--------GSELTELLDQVEGAIRDFSEELV 251
              +  +E+    QT         +   +          +L+++ D ++ +  +F +E  
Sbjct: 822 ETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKE-- 879

Query: 252 QQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMP 311
            Q  +   L+ EK  K     + ++++N  KEQ+EL K   KEK         E  +Q+ 
Sbjct: 880 NQKGKAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEK---------EASHQLK 930

Query: 312 LKRFSMEGISNILQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDLQML 363
           L+  SM+    ++Q+  + T   +  ++Q L   I   K++S    + ++ L
Sbjct: 931 LELNSMQ--EQLIQA--QNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEAL 978



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 56/272 (20%), Positives = 122/272 (44%), Gaps = 22/272 (8%)

Query: 44   SELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEE--ETLQ 101
            +ELEN   + ++ ++ ++L  E  EK++V   NY    E    +++    +E E   T Q
Sbjct: 990  TELENKLQQQLT-QAAQELAAE-KEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQ 1047

Query: 102  D----EEVWDALTDNYIPSLSEDWRDPNI--EALNGNCSDTEIHEKEEEEFNEKSENDSG 155
            D    EE      ++ I + ++      +  E      +  +   K+E++  E+ +    
Sbjct: 1048 DLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQD 1107

Query: 156  INEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTF 215
            I +E  L   +++ E  ++ +      EE +  +E++  + + +  S  L+ ++ +T   
Sbjct: 1108 IQKEKSLKEKELVNEKSKLAEI-----EEIKCRQEKEITKLNEELKSHKLESIKEIT--- 1159

Query: 216  NNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLI 275
             N    + L      EL    D ++ A+    E+  QQ+ +    + E+E+K  FI    
Sbjct: 1160 -NLKDAKQLLIQQKLELQGKADSLKAAVEQ--EKRNQQILKDQVKKEEEELKKEFIEKEA 1216

Query: 276  EVQNKQKEQRELMKKRRK-EKGLSLQSSRIEK 306
            ++ ++ KE+   MKK  + E  L++Q + + +
Sbjct: 1217 KLHSEIKEKEVGMKKHEENEAKLTMQITALNE 1248



 Score = 35.0 bits (79), Expect = 0.12
 Identities = 67/309 (21%), Positives = 114/309 (36%), Gaps = 54/309 (17%)

Query: 43  LSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQL----QIQEEEE 98
           L E    SSE +  K  E  V +   KL+        K  N   +++QL    Q  +E++
Sbjct: 437 LKEQRQLSSEKLMDK--EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQ 494

Query: 99  TLQDE------EVWDALTDNYIPSLSEDWRDPNIEALNGNCSDT-EIHEKEEEEFNEKSE 151
            LQ        E  + L         +D +  N+EAL     +   + EKE E+   K +
Sbjct: 495 ALQQSTTAKLREAQNDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQ 554

Query: 152 NDSG-------INEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEE---EDGGETSSQAD 201
              G       + E+     +QV +  E++   S   ++ +E L +   E      +  D
Sbjct: 555 AGEGETAVLNQLQEKNHTLQEQVTQLTEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQD 614

Query: 202 SVLLQE--MQALTQTFNNN------------------WSYEGLRHMSGSELTELLDQVEG 241
            VL  E  +  L    N +                   S E  +    ++L   LD  + 
Sbjct: 615 RVLSLETSVNELNSQLNESKEKVSQLDIQIKAKTELLLSAEAAKTAQRADLQNHLDTAQN 674

Query: 242 AIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQS 301
           A++D  +EL +   + D+           +T  ++ + +   Q E   K  KEK LSL+ 
Sbjct: 675 ALQDKQQELNKITTQLDQ-----------VTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723

Query: 302 SRIEKGNQM 310
              E   Q+
Sbjct: 724 KTEELEGQI 732



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 40/198 (20%), Positives = 77/198 (38%), Gaps = 13/198 (6%)

Query: 125 NIEALNGNCSDTEIHEKEE----EEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPD 180
           ++  L     D +   KEE    EE  ++ E   G+ ++       V +   E+      
Sbjct: 84  DVTLLRQEVQDLQASLKEEKWYSEELKKELEKYQGLQQQEAKPDGLVTDSSAELQSLEQQ 143

Query: 181 PEEEE-EVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQV 239
            EE + E    +   +   Q  + L  E+  +   ++   S         + LTE L++ 
Sbjct: 144 LEEAQTENFNIKQMKDLFEQKAAQLATEIADIKSKYDEERSLREAAEQKVTRLTEELNKE 203

Query: 240 EGAIRDFSEELVQQLARRDELEFEKE---VKNSFITVLIEVQNKQKEQRELMKKRR---- 292
              I+D   EL+Q+    D    +KE   V+     + +E + + ++ ++  KK +    
Sbjct: 204 ATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKKLQSQYA 263

Query: 293 -KEKGLSLQSSRIEKGNQ 309
             E  +S   S + KG Q
Sbjct: 264 SSEATISQLRSELAKGPQ 281



 Score = 28.9 bits (63), Expect = 8.4
 Identities = 49/239 (20%), Positives = 97/239 (40%), Gaps = 23/239 (9%)

Query: 80   KTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIH 139
            K+E L  +K +L  QEEE+ +  ++           +LS++ +  + E LN N   T + 
Sbjct: 791  KSEALESIKQKLTKQEEEKQILKQD---------FETLSQETKIQH-EELN-NRIQTTVT 839

Query: 140  EKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQ 199
            E ++     K E ++ + E  L T    + ++ + ++NS    E+    E + G      
Sbjct: 840  ELQK----VKMEKEALMTE--LSTVKDKLSKVSDSLKNSKSEFEK----ENQKGKAAILD 889

Query: 200  ADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDE 259
             +    +    L     N    +     S  +  E   Q++  +    E+L+Q      +
Sbjct: 890  LEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQAQNTLKQ 949

Query: 260  LEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSME 318
             E E++     I  L +   ++K+Q E ++   K     LQ + +E   Q  L + + E
Sbjct: 950  NEKEEQQLQGNINELKQSSEQKKKQIEALQGELKI--AVLQKTELENKLQQQLTQAAQE 1006


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/255 (18%), Positives = 109/255 (42%), Gaps = 31/255 (12%)

Query: 57  KSMEDLVNEFDEKLNVC---FRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNY 113
           +  E+ + E DE+L       R      E +  ++ + ++QE+E+  +D+E         
Sbjct: 393 RDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQE--------- 443

Query: 114 IPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEE 173
              + E+ R   I        + E   +E+EE  +K E +    EE      ++ E+ E+
Sbjct: 444 -EKMQEEER---IREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499

Query: 174 MMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGS--E 231
           + +     E+EE++ E+E+            +++ + +       W  E +R       E
Sbjct: 500 LWEQEKMQEQEEKIWEQEE-----------KIRDQEEMWGQEKKMWRQEKMREQEDQMWE 548

Query: 232 LTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKR 291
             E +   E  + D  E + ++   +++  +++E K      + E + K +E+ E+M  R
Sbjct: 549 QEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM--R 606

Query: 292 RKEKGLSLQSSRIEK 306
            +E+ +  Q  ++++
Sbjct: 607 EQEEKMQEQEEKMQE 621



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 44/228 (19%), Positives = 94/228 (41%), Gaps = 19/228 (8%)

Query: 80  KTENLAPVKNQLQIQEEEETLQDEEVWDA---LTDNYIPSLSEDWRDPNIEALNGNCSDT 136
           + E +   ++Q+  QEE+   Q++++WD    +         + W             + 
Sbjct: 535 RQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMRER 594

Query: 137 EIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDP--EEEEEVLEEEDG- 193
           E   +EEEE   + E      EE +   ++ + E EE MQ   +   E+EE++ E+E+  
Sbjct: 595 EKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKM 654

Query: 194 -------GETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDF 246
                   +     +   +QE + + +     W  E +   +  +  +  DQ +    + 
Sbjct: 655 WEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEES 714

Query: 247 SEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKE 294
             E  +++   +E+  E+E K      + E + K +EQ E M ++ ++
Sbjct: 715 MREREKKMREEEEMMREQEEK------MQEQEEKMQEQEEEMWEQEEK 756



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 34/185 (18%), Positives = 81/185 (43%), Gaps = 5/185 (2%)

Query: 39  EDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEE 98
           ++  + E E         +  E+++ E +EK+         + E +   + ++Q QEE+ 
Sbjct: 581 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKM 640

Query: 99  TLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINE 158
             Q+E++W+     +      + ++   E  +    + E  +++EE+  E+ + +    E
Sbjct: 641 WEQEEKMWEQEEKMWEQQRLPEQKEKLWE--HEKMQEQEKMQEQEEKIWEQEKMEKKTQE 698

Query: 159 EPLLTADQ-VIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNN 217
           +   T DQ  + E E M +      EEEE++ E++  E   + +  + ++ + + +    
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQE--EKMQEQEEKMQEQEEEMWEQEEK 756

Query: 218 NWSYE 222
            W  E
Sbjct: 757 MWEQE 761



 Score = 32.7 bits (73), Expect = 0.58
 Identities = 23/109 (21%), Positives = 52/109 (47%), Gaps = 4/109 (3%)

Query: 87  VKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGN----CSDTEIHEKE 142
           ++ Q ++QE+EE + ++E  +  T        +  +    E++         + E+  ++
Sbjct: 673 MQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQ 732

Query: 143 EEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEE 191
           EE+  E+ E      EE     +++ E+ E+M +    PE++E++ E E
Sbjct: 733 EEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHE 781



 Score = 32.3 bits (72), Expect = 0.76
 Identities = 42/225 (18%), Positives = 94/225 (41%), Gaps = 28/225 (12%)

Query: 78  NAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTE 137
           N   E +   + +L+ QE++   Q+E++W               ++  +    G   + E
Sbjct: 268 NTLQEEMWRQEEELREQEKKIRKQEEKMWR--------------QEERLREQEGKMREQE 313

Query: 138 IHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEED----- 192
                +E+   + E +    E+ L    ++ E+ E+M +      E+EE + E++     
Sbjct: 314 EKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWR 373

Query: 193 GGETSSQADSVLLQEMQALTQTFNNNWSY-EGLRHMSG--SELTELLDQVEGAIRDFSEE 249
             E   + +  + ++ Q +       W   E LR       E  ++ +QVE  +R+  + 
Sbjct: 374 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVE-KMREEKKM 432

Query: 250 LVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKKRRKE 294
             Q+   RD+ E  +E +      + E + K +E+ E M+++ ++
Sbjct: 433 QEQEKKTRDQEEKMQEEER-----IREREKKMREEEETMREQEEK 472



 Score = 29.6 bits (65), Expect = 4.9
 Identities = 32/174 (18%), Positives = 70/174 (40%), Gaps = 14/174 (8%)

Query: 39  EDPSLSELENFSSEIISFKSMEDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEE 98
           +   + E E+        +  E+++ E +EK+         + E +   + ++  QEE+ 
Sbjct: 705 DQEKMREEESMREREKKMREEEEMMREQEEKMQ-------EQEEKMQEQEEEMWEQEEKM 757

Query: 99  TLQDEEVWDALTDNYIPSLSED-WRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGIN 157
             Q+E++W+      +P   E  W    ++         E    +EE+   + E   G  
Sbjct: 758 WEQEEKMWE---QQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRG-Q 813

Query: 158 EEPLLTADQVIEEIEEMMQNSPDP--EEEEEVLEEEDGGETSSQADSVLLQEMQ 209
           EE +   ++ +   EE M    +    +EE++  +E+  E   Q     ++E +
Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQE 867


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 33/97 (34%), Positives = 48/97 (49%), Gaps = 5/97 (5%)

Query: 115 PSLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEM 174
           P+L ED    NI   N +  + E  E+EEEE  E+ E +    EE     +   EE EE 
Sbjct: 872 PALEEDLTVINI---NSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEE 928

Query: 175 MQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQAL 211
            +   + EEEE  LEEE+  E   + +   L+E++ L
Sbjct: 929 EEFEEEFEEEEGELEEEEEEEDEEEEEE--LEEVEDL 963



 Score = 35.4 bits (80), Expect = 0.089
 Identities = 38/128 (29%), Positives = 52/128 (40%), Gaps = 30/128 (23%)

Query: 79  AKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEI 138
           A  E+L  +      +EEEE  ++EE  +           E+  + + E         E 
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEE----------EEEEEEEDFE---------EE 913

Query: 139 HEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEED------ 192
            E EEE F E+ E +    EE      ++ EE EE      D EEEEE+ E ED      
Sbjct: 914 EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEE-----EDEEEEEELEEVEDLEFGTA 968

Query: 193 GGETSSQA 200
           GGE    A
Sbjct: 969 GGEVEEGA 976



 Score = 28.9 bits (63), Expect = 8.4
 Identities = 24/101 (23%), Positives = 40/101 (39%), Gaps = 13/101 (12%)

Query: 162 LTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSY 221
           LT   +    EE  +   + EEEEE  EEE+  E   + +    +E +   + F      
Sbjct: 878 LTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE----- 932

Query: 222 EGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEF 262
                    E  E   ++E    +  EE  ++L   ++LEF
Sbjct: 933 --------EEFEEEEGELEEEEEEEDEEEEEELEEVEDLEF 965


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 75/347 (21%), Positives = 147/347 (42%), Gaps = 48/347 (13%)

Query: 1    MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME 60
            +E  L   DEE E+ R         K QC   S    L+  + S +E    +    K ME
Sbjct: 1584 LERKLSEKDEEIENFR--------RKQQCTIDSLQSSLDSEAKSRIEVTRLK----KKME 1631

Query: 61   DLVNEFDEKLNVCFRNYNAKTENLAPVKNQ---LQIQEEEETLQDEEVWDALT-----DN 112
            + +NE + +L+   R  +  T++L  ++ Q   LQ+Q ++ T  + ++ + +      ++
Sbjct: 1632 EDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNS 1691

Query: 113  YIPSLSEDWRDPNIEALNG-NCSDTEIHEKEEEEFNEKSENDSGINEEPLLTAD--QVIE 169
             + S  ED R    +   G   S+ E+ E  E      ++N S ++++  L AD  ++ +
Sbjct: 1692 LLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADVARMQK 1751

Query: 170  EIEEMMQNSPDPEEE------------EEVLEEEDG----GETSSQADSVL--LQEMQAL 211
            E EE++Q   + EE+            EE+ +++D       T    +  +  LQ+  A 
Sbjct: 1752 EAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENMEQTITDLQKRLAE 1811

Query: 212  TQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFI 271
             +      S + ++ +  S + EL  ++EG IR  +E      A+R     E+ +K    
Sbjct: 1812 AEQMALMGSRKQIQKLE-SRVRELEGELEGEIRRSAE------AQRGARRLERCIKELTY 1864

Query: 272  TVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSME 318
                + +N  + Q ++ K + K +    Q    E      L ++  +
Sbjct: 1865 QAEEDKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQ 1911



 Score = 32.3 bits (72), Expect = 0.76
 Identities = 74/380 (19%), Positives = 140/380 (36%), Gaps = 48/380 (12%)

Query: 1    MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKSME 60
            +E     L +E +DL     +  +EK       +  H       E+E  + +I       
Sbjct: 955  LEDECFELKKEIDDLETMLVKSEKEK------RTTEHKVKNLTEEVEFLNEDISKLNRAA 1008

Query: 61   DLVNEFDEKLNVCFRNYNAKTENL--APVKNQLQIQEEEETLQDEEVWDALTDNYIPSLS 118
             +V E  ++          K  +L  A +K + Q+ E E  L+ E       +  +  L 
Sbjct: 1009 KVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCERELHKLE 1068

Query: 119  EDWR-----DPNIEALNGNCSDTEIHEKEEE--EFNEKSENDSGINEEPLLTADQVIEEI 171
             + +       N+E+   + ++ E+ +KE E  + N K EN+ G+  +   T  ++  +I
Sbjct: 1069 GNLKLNRESMENLESSQRHLAE-ELRKKELELSQMNSKVENEKGLVAQLQKTVKELQTQI 1127

Query: 172  EEMMQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSE 231
            +++ +           +E E    T   AD                    E L  + GS 
Sbjct: 1128 KDLKEKLEAERTTRAKMERERADLTQDLAD------------------LNERLEEVGGSS 1169

Query: 232  LTELLDQVEGAIRDFSEELVQQLARRDE---LEFE---KEVKNSFITVLIEVQNKQKEQR 285
            L +L       I    E   Q+L R  E   L FE     +K      L E++ + +  +
Sbjct: 1170 LAQL------EITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQ 1223

Query: 286  ELMKKRRKEKG-LSLQ-SSRIEKGNQMPLKRFSMEGISNILQSGIRQTFGSSGTDKQYLN 343
            ++ +K  K+K  L L+    + +  QM   + + E +  + +  + +         Q  N
Sbjct: 1224 QVKQKLEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLAN 1283

Query: 344  TVIPYEKKASPPSVEDLQML 363
             +   + K    S E L+ L
Sbjct: 1284 DLAAQKTKLWSESGEFLRRL 1303


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 74/354 (20%), Positives = 137/354 (38%), Gaps = 40/354 (11%)

Query: 37  HLEDPSLSELENFS---SEIISFKSMEDLVNE--------FDEKLNVCFRNYNAKTENLA 85
           H++D    E E+     +E++  K  +  V E         +++       +N + ++L 
Sbjct: 371 HIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLK 430

Query: 86  PVKNQLQIQEEEETLQDEEVWDALTDNY-IPSLSEDWRDPNIEALNGNCSDTEIHEKEEE 144
             ++Q +I E  ET   +   + LT  + I  L E   +   E      +   + E  E 
Sbjct: 431 E-QHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEI 489

Query: 145 EFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETSSQADSVL 204
              E  E+   I++E      Q   ++ E+ Q       E++ L E            + 
Sbjct: 490 LQTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDALLETVNRLQGENEKLLS 549

Query: 205 LQEM-QALTQTFNNNWSYEGLRHMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFE 263
            QE+   L  T  N     G+  +S S+   +L ++EG I   +EE              
Sbjct: 550 QQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEE-------------- 595

Query: 264 KEVKNSFITVLIEVQNKQKEQRELMKKRRKEKGLSLQSSRIEKGNQMPLKRFSMEGISNI 323
              K+ FI    +++N  +E     KK  +E+ L L+  +  K  Q       +E   N 
Sbjct: 596 ---KDDFIN---KLKNSHEEMDNFHKKCEREERLILELGK--KVEQTIQYNSELEQKVNE 647

Query: 324 LQSGIRQTFGSSGTDKQYLNTVIPYEKKASPPSVEDLQMLTNILFAMKEDNEKV 377
           L  G+ +T      + Q L  ++   K  S    ED ++L+  + ++ E+N K+
Sbjct: 648 LTGGLEETLKEKDQNDQKLEKLMVQMKVLS----EDKEVLSAEVKSLYEENNKL 697



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 55/225 (24%), Positives = 102/225 (45%), Gaps = 30/225 (13%)

Query: 68   EKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIE 127
            E+L    R+Y  + E +   K   +IQ E+E LQ + + +    N    L        +E
Sbjct: 827  EELKSLLRDY--EQEKVLLRKELEEIQSEKEALQSD-LLEMKNANEKTRLENQNLLIQVE 883

Query: 128  ALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLL---TADQVIEEIEEMMQNSP----D 180
             ++  CS +EIH ++E+ F ++ EN   + E+  L    A+ ++  +++ +  SP    D
Sbjct: 884  EVSQTCSKSEIHNEKEKCFIKEHENLKPLLEQKELRDRRAELIL--LKDSLAKSPSVKND 941

Query: 181  P----EEEEEVLE--EEDGGETSSQADSVLLQEMQAL---------TQTFNNNWSYEGLR 225
            P    +E EE +E  E++  E   + + + L  ++A          TQT       E LR
Sbjct: 942  PLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKE--ELESLR 999

Query: 226  HMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSF 270
                     + D ++GA   +   L++   + ++L+ EKE  N+F
Sbjct: 1000 SEKDQLSASMRDLIQGA-ESYKNLLLEYEKQSEQLDVEKERANNF 1043



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 60/300 (20%), Positives = 118/300 (39%), Gaps = 27/300 (9%)

Query: 1   MEAPLVSLDEEFEDLRPSCSEDPEEKPQCFYGSSPHHLEDPSLSELENFSSEIISFKS-M 59
           +E  + SL EE +D         EE    F+       E+  + EL     + I + S +
Sbjct: 585 LEGKINSLTEEKDDFINKLKNSHEEMDN-FHKKCER--EERLILELGKKVEQTIQYNSEL 641

Query: 60  EDLVNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSE 119
           E  VNE    L    +  +   + L  +  Q+++  E++ +   EV     +N   S  +
Sbjct: 642 EQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEK 701

Query: 120 DWRDPNIEALNGNCSDTEIHE-------------KEEEEFNEKSENDSGINEEPLLTADQ 166
                ++E       D  + E             +E++  N+  EN+     + L    Q
Sbjct: 702 KQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQ---VQKLFVKTQ 758

Query: 167 VIEEIEEM-MQNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLR 225
           +   ++EM  + S D EE++ V   +  GE+ ++ +    ++     Q        E   
Sbjct: 759 LYGFLKEMGSEVSEDSEEKDVVNVLQAVGESLAKINE---EKCNLAFQRDEKVLELEKEI 815

Query: 226 HMSGSELTELLDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQR 285
                E     ++++  +RD+ +E V      +E++ EKE   S    L+E++N  ++ R
Sbjct: 816 KCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQS---DLLEMKNANEKTR 872



 Score = 35.8 bits (81), Expect = 0.068
 Identities = 67/295 (22%), Positives = 120/295 (40%), Gaps = 43/295 (14%)

Query: 2   EAPLVSLDEEFEDLRPSCSEDPEEKPQCFYG-SSPHHLEDPSLSELENFSSEIIS-FKSM 59
           E   ++L  E + L+  C    +EK +      S   + +   +EL   + +I   F+SM
Sbjct: 449 EKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESM 508

Query: 60  EDL----VNEFDEKLNVCFRNYNAKTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIP 115
           +      V+E  +KL   F   +A  E +    N+LQ  E E+ L  +E+   L +N I 
Sbjct: 509 KQQQASDVHELQQKLRTAFTEKDALLETV----NRLQ-GENEKLLSQQELVPEL-ENTIK 562

Query: 116 SLSEDWRDPNIEALNGNCSDTEIHEKEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMM 175
           +L E      +  L+ +  DT + E E +  +   E D  IN+         ++   E M
Sbjct: 563 NLQEK---NGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINK---------LKNSHEEM 610

Query: 176 QNSPDPEEEEEVLEEEDGGETSSQADSVLLQEMQALTQTFNNNWSYEGLRHMSGSELTEL 235
            N     E EE L               +L+  + + QT   N   E       +ELT  
Sbjct: 611 DNFHKKCEREERL---------------ILELGKKVEQTIQYNSELE----QKVNELTGG 651

Query: 236 LDQVEGAIRDFSEELVQQLARRDELEFEKEVKNSFITVLIEVQNKQKEQRELMKK 290
           L++         ++L + + +   L  +KEV ++ +  L E  NK   +++ + +
Sbjct: 652 LEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLSR 706


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 37/125 (29%), Positives = 54/125 (43%), Gaps = 25/125 (20%)

Query: 80  KTENLAPVKNQLQIQEEEETLQDEEVWDALTDNYIPSLSEDWRDPNIEALNGNCSDTEIH 139
           K E   PV+ + +   E+  L D   W+A+             D   E + GN    E+ 
Sbjct: 483 KEETPPPVEPEEEEDTEDAGLDD---WEAMAS-----------DEETEKVEGNKVHIEVK 528

Query: 140 E--KEEEEFNEKSENDSGINEEPLLTADQVIEEIEEMMQNSPDPEEEEEVLEEEDGGETS 197
           E  +EEEE  E+ E D    EE         EE E   + S   EE+E+V +E+D G+T 
Sbjct: 529 ENPEEEEEEEEEEEEDEESEEE---------EEEEGESEGSEGDEEDEKVSDEKDSGKTL 579

Query: 198 SQADS 202
            +  S
Sbjct: 580 DKKPS 584


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.307    0.128    0.348 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,646,731
Number of Sequences: 37866
Number of extensions: 781937
Number of successful extensions: 8065
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 137
Number of HSP's successfully gapped in prelim test: 526
Number of HSP's that attempted gapping in prelim test: 5169
Number of HSP's gapped (non-prelim): 2076
length of query: 392
length of database: 18,247,518
effective HSP length: 104
effective length of query: 288
effective length of database: 14,309,454
effective search space: 4121122752
effective search space used: 4121122752
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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