Search of human proteins with 48255951

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo
sapiens]
         (1243 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sap...  2463   0.0  
gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap...  2357   0.0  
gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa...  2013   0.0  
gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo sa...  1980   0.0  
gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa...  1889   0.0  
gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa...  1821   0.0  
gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo sa...  1771   0.0  
gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo sa...  1714   0.0  
gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap...   263   1e-69
gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap...   263   1e-69
gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap...   263   1e-69
gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap...   259   9e-69
gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ...   256   1e-67
gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H...   249   2e-65
gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [...   249   2e-65
gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]   248   2e-65
gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom...   244   4e-64
gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   244   4e-64
gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom...   244   4e-64
gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom...   244   4e-64
gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom...   244   4e-64
gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom...   244   4e-64
gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom...   244   4e-64
gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ...   240   5e-63
gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [...   238   2e-62
gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [...   238   2e-62
gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi...   231   2e-60
gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi...   231   2e-60
gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]   231   2e-60
gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi...   227   6e-59

>gi|48255951 plasma membrane calcium ATPase 2 isoform 1 [Homo sapiens]
          Length = 1243

 Score = 2463 bits (6384), Expect = 0.0
 Identities = 1243/1243 (100%), Positives = 1243/1243 (100%)

Query: 1    MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 60
            MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL
Sbjct: 1    MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 60

Query: 61   KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 120
            KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG
Sbjct: 61   KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 120

Query: 121  LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 180
            LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR
Sbjct: 121  LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 180

Query: 181  GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 240
            GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS
Sbjct: 181  GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 240

Query: 241  LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 300
            LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD
Sbjct: 241  LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 300

Query: 301  KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ 360
            KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ
Sbjct: 301  KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ 360

Query: 361  PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 420
            PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT
Sbjct: 361  PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 420

Query: 421  FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 480
            FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
Sbjct: 421  FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 480

Query: 481  VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 540
            VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN
Sbjct: 481  VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 540

Query: 541  AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 600
            AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY
Sbjct: 541  AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 600

Query: 601  TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 660
            TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV
Sbjct: 601  TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 660

Query: 661  IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 720
            IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC
Sbjct: 661  IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 720

Query: 721  QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 780
            QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK
Sbjct: 721  QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 780

Query: 781  IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 840
            IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA
Sbjct: 781  IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 840

Query: 841  GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 900
            GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
Sbjct: 841  GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 900

Query: 901  QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 960
            QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV
Sbjct: 901  QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 960

Query: 961  YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 1020
            YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER
Sbjct: 961  YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 1020

Query: 1021 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1080
            NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV
Sbjct: 1021 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1080

Query: 1081 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1140
            IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ
Sbjct: 1081 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1140

Query: 1141 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1200
            IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS
Sbjct: 1141 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1200

Query: 1201 SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1243
            SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL
Sbjct: 1201 SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1243


>gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens]
          Length = 1198

 Score = 2357 bits (6107), Expect = 0.0
 Identities = 1198/1243 (96%), Positives = 1198/1243 (96%), Gaps = 45/1243 (3%)

Query: 1    MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 60
            MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL
Sbjct: 1    MGDMTNSDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRL 60

Query: 61   KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 120
            KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG
Sbjct: 61   KTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLG 120

Query: 121  LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 180
            LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR
Sbjct: 121  LSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFR 180

Query: 181  GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 240
            GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS
Sbjct: 181  GLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESS 240

Query: 241  LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 300
            LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD
Sbjct: 241  LTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKD 300

Query: 301  KKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQ 360
            KK                                             AKQQDGAAAMEMQ
Sbjct: 301  KK---------------------------------------------AKQQDGAAAMEMQ 315

Query: 361  PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 420
            PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT
Sbjct: 316  PLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 375

Query: 421  FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 480
            FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
Sbjct: 376  FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 435

Query: 481  VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 540
            VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN
Sbjct: 436  VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 495

Query: 541  AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 600
            AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY
Sbjct: 496  AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 555

Query: 601  TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 660
            TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV
Sbjct: 556  TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 615

Query: 661  IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 720
            IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC
Sbjct: 616  IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 675

Query: 721  QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 780
            QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK
Sbjct: 676  QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 735

Query: 781  IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 840
            IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA
Sbjct: 736  IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 795

Query: 841  GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 900
            GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
Sbjct: 796  GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 855

Query: 901  QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 960
            QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV
Sbjct: 856  QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 915

Query: 961  YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 1020
            YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER
Sbjct: 916  YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 975

Query: 1021 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1080
            NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV
Sbjct: 976  NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1035

Query: 1081 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1140
            IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ
Sbjct: 1036 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1095

Query: 1141 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1200
            IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS
Sbjct: 1096 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1155

Query: 1201 SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1243
            SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL
Sbjct: 1156 SPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1198


>gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo
            sapiens]
          Length = 1220

 Score = 2013 bits (5216), Expect = 0.0
 Identities = 1020/1252 (81%), Positives = 1109/1252 (88%), Gaps = 41/1252 (3%)

Query: 1    MGDMTNS--DFYSK-NQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
            MGDM NS  +F+ K  Q+ +    G FGCT+ ELR+LMELRG EA+ KI+E YGD   +C
Sbjct: 1    MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60

Query: 58   RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
            RRLKTSP EGL     DLEKR+QI+GQNFIPPK+PKTFLQLVWEALQDVTLIILE+AAI+
Sbjct: 61   RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120

Query: 118  SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
            SLGLSFY PPGE +E C    GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK
Sbjct: 121  SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180

Query: 178  QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
            QFRGLQSRIEQEQKFTV+R GQ++Q+PVA +VVGDIAQVKYGDLLPADG+ IQ NDLKID
Sbjct: 181  QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240

Query: 238  ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
            ESSLTGESD VRKS DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 241  ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300

Query: 298  KKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAM 357
            KKDKKG                               K QDG +++SQ+KAK+QDGA AM
Sbjct: 301  KKDKKG-------------------------------KQQDGAMESSQTKAKKQDGAVAM 329

Query: 358  EMQPLKSAEGGDADDR--KKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 415
            EMQPLKSAEGG+ ++R  KKA+  KKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY
Sbjct: 330  EMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 389

Query: 416  FTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 475
            F ++TFVV  + WL ECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM
Sbjct: 390  FVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 449

Query: 476  KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTM 535
            KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQ+Y+GD HYKEIP PS++  K +
Sbjct: 450  KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKIL 509

Query: 536  ELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK 595
            +LL++AI+INSAYTTKILPPEKEGALPRQVGNKTEC LLGFVLDLK+D++PVR Q+PE+K
Sbjct: 510  DLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQIPEDK 569

Query: 596  LYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDE 655
            LYKVYTFNSVRKSMSTVI++PD  FR++SKGASEI+LKKC  ILN  GE R FRPRDRD+
Sbjct: 570  LYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDD 629

Query: 656  MVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPE 715
            MV+K+IEPMACDGLRTIC+AYRDF +  EPDWDNEN+++ +LTCI VVGIEDPVRPEVPE
Sbjct: 630  MVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPE 689

Query: 716  AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQ 775
            AIRKCQRAGITVRMVTGDNINTARAIA KCGII PGEDFLCLEGKEFNRRIRNEKGEIEQ
Sbjct: 690  AIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQ 749

Query: 776  ERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGF 835
            ER+DK+WPKLRVLARSSPTDKHTLVKGIIDST  EQRQVVAVTGDGTNDGPALKKADVGF
Sbjct: 750  ERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGF 809

Query: 836  AMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT 895
            AMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT
Sbjct: 810  AMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT 869

Query: 896  GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNI 955
            GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE+LLLRKPYGR+KPLISRTMMKNI
Sbjct: 870  GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNI 929

Query: 956  LGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK 1015
            LGHAVYQLA+IFTLLFVGE  F IDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK
Sbjct: 930  LGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK 989

Query: 1016 IHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGEL 1075
            IHGERNVFDGIF NPIFCTIVLGTF IQIVIVQFGGKPFSCSPL  +QW+WC+F+G+GEL
Sbjct: 990  IHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGEL 1049

Query: 1076 VWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLN 1135
            VWGQVIATIPTS+LK LKEAG    K+E+ +EEL E  EEIDHAERELRRGQILWFRGLN
Sbjct: 1050 VWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILWFRGLN 1109

Query: 1136 RIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAA 1195
            RIQTQIRVVKAFRSSLYEGLEKPES+TSIHNFMA PEF I D   +IPLIDDTD++E+  
Sbjct: 1110 RIQTQIRVVKAFRSSLYEGLEKPESKTSIHNFMATPEFLINDYTHNIPLIDDTDVDENEE 1169

Query: 1196 LKQNSSPPSSLNKNNSAIDSGINLTTDTSKSAT----SSSPGSPIHSLETSL 1243
             +  + PP S N+NN+AIDSGI LTT  +KSAT    SSSPGSP+HS+ETSL
Sbjct: 1170 -RLRAPPPPSPNQNNNAIDSGIYLTTHVTKSATSSVFSSSPGSPLHSVETSL 1220


>gi|48255945 plasma membrane calcium ATPase 1 isoform 1b [Homo
            sapiens]
          Length = 1220

 Score = 1980 bits (5130), Expect = 0.0
 Identities = 996/1249 (79%), Positives = 1103/1249 (88%), Gaps = 35/1249 (2%)

Query: 1    MGDMTNSDF-YS--KNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
            MGDM N+   YS  KN   E++H G+FG T+ ELR+LMELR T+A+ KI+E+YGD   IC
Sbjct: 1    MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60

Query: 58   RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
             +LKTSP EGL G   DLE+R+ +FG+NFIPPKKPKTFLQLVWEALQDVTLIILEIAAI+
Sbjct: 61   TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120

Query: 118  SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
            SLGLSFY PP   N  C     G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK
Sbjct: 121  SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179

Query: 178  QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
            QFRGLQSRIEQEQKFTV+R GQV+QIPVA+I VGDIAQVKYGDLLPADG+ IQGNDLKID
Sbjct: 180  QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239

Query: 238  ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
            ESSLTGESD V+KS+DKDP+LLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 240  ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299

Query: 298  KKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAM 357
            KKD+K  +K                            K QDG ++ +++KAK QDGAA M
Sbjct: 300  KKDEKKKEK--------------------------KNKKQDGAIE-NRNKAKAQDGAA-M 331

Query: 358  EMQPLKSAEGGDAD--DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 415
            EMQPLKS EGGD D  D+KKA++ KKEKSVLQGKLTKLAVQIGKAGL+MSAITVIILVLY
Sbjct: 332  EMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLY 391

Query: 416  FTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 475
            F +DTF V K+PWL ECTP+Y+QYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM
Sbjct: 392  FVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 451

Query: 476  KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTM 535
            KDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQAY+ + HYK++P+P +I    +
Sbjct: 452  KDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNIL 511

Query: 536  ELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK 595
              L+  I++N AYT+KILPPEKEG LPR VGNKTEC LLG +LDLK+DY+ VR+++PEE 
Sbjct: 512  SYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEA 571

Query: 596  LYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDE 655
            LYKVYTFNSVRKSMSTV+K  D S+R++SKGASEI+LKKC KIL+  GE +VFRPRDRD+
Sbjct: 572  LYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDD 631

Query: 656  MVKKVIEPMACDGLRTICVAYRDFPSS-PEPDWDNENDILNELTCICVVGIEDPVRPEVP 714
            +VK VIEPMA +GLRTIC+A+RDFP+  PEP+WDNENDI+  LTCI VVGIEDPVRPEVP
Sbjct: 632  IVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVP 691

Query: 715  EAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIE 774
            +AI+KCQRAGITVRMVTGDNINTARAIA KCGI+HPGEDFLCLEGK+FNRRIRNEKGEIE
Sbjct: 692  DAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIE 751

Query: 775  QERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVG 834
            QERIDKIWPKLRVLARSSPTDKHTLVKGIIDST ++QRQVVAVTGDGTNDGPALKKADVG
Sbjct: 752  QERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVG 811

Query: 835  FAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 894
            FAMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF
Sbjct: 812  FAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 871

Query: 895  TGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKN 954
            TGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTE+LLLRKPYGRNKPLISRTMMKN
Sbjct: 872  TGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKN 931

Query: 955  ILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINAR 1014
            ILGHA YQL ++FTLLF GEK F IDSGRNAPLH+PPSEHYTI+FNTFV+MQLFNEINAR
Sbjct: 932  ILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINAR 991

Query: 1015 KIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGE 1074
            KIHGERNVF+GIF N IFCTIVLGTF +QI+IVQFGGKPFSCS L ++QW+W IF+G+G 
Sbjct: 992  KIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGT 1051

Query: 1075 LVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGL 1134
            L+WGQ+I+TIPTSRLKFLKEAG  TQKEEIPEEEL EDVEEIDHAERELRRGQILWFRGL
Sbjct: 1052 LLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEIDHAERELRRGQILWFRGL 1111

Query: 1135 NRIQTQIRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDA 1194
            NRIQTQIRVV AFRSSLYEGLEKPESR+SIHNFM HPEFRIEDS+PHIPLIDDTD E+DA
Sbjct: 1112 NRIQTQIRVVNAFRSSLYEGLEKPESRSSIHNFMTHPEFRIEDSEPHIPLIDDTDAEDDA 1171

Query: 1195 ALKQNSSPPSSLNKNNSAIDSGINLTTDTSKSATSSSPGSPIHSLETSL 1243
              K+NSSPP S NKNN+A+DSGI+LT + +KSATSSSPGSP+HSLETSL
Sbjct: 1172 PTKRNSSPPPSPNKNNNAVDSGIHLTIEMNKSATSSSPGSPLHSLETSL 1220


>gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo
            sapiens]
          Length = 1173

 Score = 1889 bits (4892), Expect = 0.0
 Identities = 950/1155 (82%), Positives = 1029/1155 (89%), Gaps = 36/1155 (3%)

Query: 1    MGDMTNS--DFYSK-NQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
            MGDM NS  +F+ K  Q+ +    G FGCT+ ELR+LMELRG EA+ KI+E YGD   +C
Sbjct: 1    MGDMANSSIEFHPKPQQQRDVPQAGGFGCTLAELRTLMELRGAEALQKIEEAYGDVSGLC 60

Query: 58   RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
            RRLKTSP EGL     DLEKR+QI+GQNFIPPK+PKTFLQLVWEALQDVTLIILE+AAI+
Sbjct: 61   RRLKTSPTEGLADNTNDLEKRRQIYGQNFIPPKQPKTFLQLVWEALQDVTLIILEVAAIV 120

Query: 118  SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
            SLGLSFY PPGE +E C    GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK
Sbjct: 121  SLGLSFYAPPGEESEACGNVSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 180

Query: 178  QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
            QFRGLQSRIEQEQKFTV+R GQ++Q+PVA +VVGDIAQVKYGDLLPADG+ IQ NDLKID
Sbjct: 181  QFRGLQSRIEQEQKFTVIRNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKID 240

Query: 238  ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
            ESSLTGESD VRKS DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 241  ESSLTGESDHVRKSADKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 300

Query: 298  KKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAM 357
            KKDKKG                               K QDG +++SQ+KAK+QDGA AM
Sbjct: 301  KKDKKG-------------------------------KQQDGAMESSQTKAKKQDGAVAM 329

Query: 358  EMQPLKSAEGGDADDR--KKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 415
            EMQPLKSAEGG+ ++R  KKA+  KKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY
Sbjct: 330  EMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 389

Query: 416  FTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 475
            F ++TFVV  + WL ECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM
Sbjct: 390  FVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 449

Query: 476  KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTM 535
            KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQ+Y+GD HYKEIP PS++  K +
Sbjct: 450  KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYLGDTHYKEIPAPSALTPKIL 509

Query: 536  ELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK 595
            +LL++AI+INSAYTTKILPPEKEGALPRQVGNKTEC LLGFVLDLK+D++PVR Q+PE+K
Sbjct: 510  DLLVHAISINSAYTTKILPPEKEGALPRQVGNKTECALLGFVLDLKRDFQPVREQIPEDK 569

Query: 596  LYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDE 655
            LYKVYTFNSVRKSMSTVI++PD  FR++SKGASEI+LKKC  ILN  GE R FRPRDRD+
Sbjct: 570  LYKVYTFNSVRKSMSTVIRMPDGGFRLFSKGASEILLKKCTNILNSNGELRGFRPRDRDD 629

Query: 656  MVKKVIEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPE 715
            MV+K+IEPMACDGLRTIC+AYRDF +  EPDWDNEN+++ +LTCI VVGIEDPVRPEVPE
Sbjct: 630  MVRKIIEPMACDGLRTICIAYRDFSAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPE 689

Query: 716  AIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQ 775
            AIRKCQRAGITVRMVTGDNINTARAIA KCGII PGEDFLCLEGKEFNRRIRNEKGEIEQ
Sbjct: 690  AIRKCQRAGITVRMVTGDNINTARAIAAKCGIIQPGEDFLCLEGKEFNRRIRNEKGEIEQ 749

Query: 776  ERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGF 835
            ER+DK+WPKLRVLARSSPTDKHTLVKGIIDST  EQRQVVAVTGDGTNDGPALKKADVGF
Sbjct: 750  ERLDKVWPKLRVLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGF 809

Query: 836  AMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT 895
            AMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT
Sbjct: 810  AMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFT 869

Query: 896  GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNI 955
            GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTE+LLLRKPYGR+KPLISRTMMKNI
Sbjct: 870  GACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNI 929

Query: 956  LGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK 1015
            LGHAVYQLA+IFTLLFVGE  F IDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK
Sbjct: 930  LGHAVYQLAIIFTLLFVGELFFDIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARK 989

Query: 1016 IHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGEL 1075
            IHGERNVFDGIF NPIFCTIVLGTF IQIVIVQFGGKPFSCSPL  +QW+WC+F+G+GEL
Sbjct: 990  IHGERNVFDGIFSNPIFCTIVLGTFGIQIVIVQFGGKPFSCSPLSTEQWLWCLFVGVGEL 1049

Query: 1076 VWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLN 1135
            VWGQVIATIPTS+LK LKEAG    K+E+ +EEL E  EEIDHAERELRRGQILWFRGLN
Sbjct: 1050 VWGQVIATIPTSQLKCLKEAGHGPGKDEMTDEELAEGEEEIDHAERELRRGQILWFRGLN 1109

Query: 1136 RIQTQIRVVKAFRSS 1150
            RIQTQ+ VV  F+ S
Sbjct: 1110 RIQTQMEVVSTFKRS 1124


>gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo
            sapiens]
          Length = 1176

 Score = 1821 bits (4717), Expect = 0.0
 Identities = 922/1174 (78%), Positives = 1024/1174 (87%), Gaps = 37/1174 (3%)

Query: 1    MGDMTNSDF-YS--KNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAIC 57
            MGDM N+   YS  KN   E++H G+FG T+ ELR+LMELR T+A+ KI+E+YGD   IC
Sbjct: 1    MGDMANNSVAYSGVKNSLKEANHDGDFGITLAELRALMELRSTDALRKIQESYGDVYGIC 60

Query: 58   RRLKTSPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAII 117
             +LKTSP EGL G   DLE+R+ +FG+NFIPPKKPKTFLQLVWEALQDVTLIILEIAAI+
Sbjct: 61   TKLKTSPNEGLSGNPADLERREAVFGKNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIV 120

Query: 118  SLGLSFYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEK 177
            SLGLSFY PP   N  C     G E+EGE E GWIEGAAILLSV+CVVLVTAFNDWSKEK
Sbjct: 121  SLGLSFYQPPEGDNALCGEVSVG-EEEGEGETGWIEGAAILLSVVCVVLVTAFNDWSKEK 179

Query: 178  QFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKID 237
            QFRGLQSRIEQEQKFTV+R GQV+QIPVA+I VGDIAQVKYGDLLPADG+ IQGNDLKID
Sbjct: 180  QFRGLQSRIEQEQKFTVIRGGQVIQIPVADITVGDIAQVKYGDLLPADGILIQGNDLKID 239

Query: 238  ESSLTGESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEE 297
            ESSLTGESD V+KS+DKDP+LLSGTHVMEGSGRM+VTAVGVNSQTGIIFTLLGAGGEEEE
Sbjct: 240  ESSLTGESDHVKKSLDKDPLLLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEE 299

Query: 298  KKDKKGVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAM 357
            KKD+K  +K                            K QDG ++ +++KAK QDGAA M
Sbjct: 300  KKDEKKKEK--------------------------KNKKQDGAIE-NRNKAKAQDGAA-M 331

Query: 358  EMQPLKSAEGGDAD--DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLY 415
            EMQPLKS EGGD D  D+KKA++ KKEKSVLQGKLTKLAVQIGKAGL+MSAITVIILVLY
Sbjct: 332  EMQPLKSEEGGDGDEKDKKKANLPKKEKSVLQGKLTKLAVQIGKAGLLMSAITVIILVLY 391

Query: 416  FTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 475
            F +DTF V K+PWL ECTP+Y+QYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM
Sbjct: 392  FVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMM 451

Query: 476  KDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTM 535
            KDNNLVRHLDACETMGNATAICSDKTGTLT NRMTVVQAY+ + HYK++P+P +I    +
Sbjct: 452  KDNNLVRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYINEKHYKKVPEPEAIPPNIL 511

Query: 536  ELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEK 595
              L+  I++N AYT+KILPPEKEG LPR VGNKTEC LLG +LDLK+DY+ VR+++PEE 
Sbjct: 512  SYLVTGISVNCAYTSKILPPEKEGGLPRHVGNKTECALLGLLLDLKRDYQDVRNEIPEEA 571

Query: 596  LYKVYTFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDE 655
            LYKVYTFNSVRKSMSTV+K  D S+R++SKGASEI+LKKC KIL+  GE +VFRPRDRD+
Sbjct: 572  LYKVYTFNSVRKSMSTVLKNSDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDD 631

Query: 656  MVKKVIEPMACDGLRTICVAYRDFPSS-PEPDWDNENDILNELTCICVVGIEDPVRPEVP 714
            +VK VIEPMA +GLRTIC+A+RDFP+  PEP+WDNENDI+  LTCI VVGIEDPVRPEVP
Sbjct: 632  IVKTVIEPMASEGLRTICLAFRDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVP 691

Query: 715  EAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIE 774
            +AI+KCQRAGITVRMVTGDNINTARAIA KCGI+HPGEDFLCLEGK+FNRRIRNEKGEIE
Sbjct: 692  DAIKKCQRAGITVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRIRNEKGEIE 751

Query: 775  QERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVG 834
            QERIDKIWPKLRVLARSSPTDKHTLVKGIIDST ++QRQVVAVTGDGTNDGPALKKADVG
Sbjct: 752  QERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTVSDQRQVVAVTGDGTNDGPALKKADVG 811

Query: 835  FAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 894
            FAMGIAGTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF
Sbjct: 812  FAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAF 871

Query: 895  TGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKN 954
            TGACITQDSPLKAVQMLWVNLIMDT ASLALATEPPTE+LLLRKPYGRNKPLISRTMMKN
Sbjct: 872  TGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRNKPLISRTMMKN 931

Query: 955  ILGHAVYQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINAR 1014
            ILGHA YQL ++FTLLF GEK F IDSGRNAPLH+PPSEHYTI+FNTFV+MQLFNEINAR
Sbjct: 932  ILGHAFYQLVVVFTLLFAGEKFFDIDSGRNAPLHAPPSEHYTIVFNTFVLMQLFNEINAR 991

Query: 1015 KIHGERNVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGE 1074
            KIHGERNVF+GIF N IFCTIVLGTF +QI+IVQFGGKPFSCS L ++QW+W IF+G+G 
Sbjct: 992  KIHGERNVFEGIFNNAIFCTIVLGTFVVQIIIVQFGGKPFSCSELSIEQWLWSIFLGMGT 1051

Query: 1075 LVWGQVIATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGL 1134
            L+WGQ+I+TIPTSRLKFLKEAG  TQKEEIPEEEL EDVEEIDHAERELRRGQILWFRGL
Sbjct: 1052 LLWGQLISTIPTSRLKFLKEAGHGTQKEEIPEEELAEDVEEIDHAERELRRGQILWFRGL 1111

Query: 1135 NRIQTQIRVVKAFR--SSLYEGLEKPESRTSIHN 1166
            NRIQTQ+ VV AF+  SS+   L +  S  S H+
Sbjct: 1112 NRIQTQMDVVNAFQSGSSIQGALRRQPSIASQHH 1145


>gi|48255957 plasma membrane calcium ATPase 4 isoform 4b [Homo
            sapiens]
          Length = 1205

 Score = 1771 bits (4586), Expect = 0.0
 Identities = 900/1249 (72%), Positives = 1024/1249 (81%), Gaps = 53/1249 (4%)

Query: 4    MTN-SDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRLKT 62
            MTN SD          S  G+FGCT+ ELR LMELR  +A+ +I   YG  + +C RLKT
Sbjct: 1    MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60

Query: 63   SPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLS 122
            SPVEGL G   DLEKR+Q+FG N IPPKKPKTFL+LVWEALQDVTLIILEIAAIISL LS
Sbjct: 61   SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120

Query: 123  FYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 182
            FY P GE NE C       EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGL
Sbjct: 121  FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180

Query: 183  QSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLT 242
            Q RIEQEQKF+++R GQ++Q+PVAEIVVGDIAQVKYGDLLPADG+ IQGNDLKIDESSLT
Sbjct: 181  QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240

Query: 243  GESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
            GESD V+KS+DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGII TLLG   ++E +K KK
Sbjct: 241  GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300

Query: 303  GVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQPL 362
            G K+G                                 V  +++KAK QDG A +E+QPL
Sbjct: 301  GKKQG---------------------------------VPENRNKAKTQDGVA-LEIQPL 326

Query: 363  KSAEGGDAD--DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 420
             S EG D +  D+K   + KKEKSVLQGKLT+LAVQIGKAGL+MSA+TV IL+LYF +D 
Sbjct: 327  NSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDN 386

Query: 421  FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 480
            FV+N++PWLPECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
Sbjct: 387  FVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 446

Query: 481  VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 540
            VRHLDACETMGNATAICSDKTGTLT NRMTVVQAY+G +HY++IP P     K ++L++N
Sbjct: 447  VRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVN 506

Query: 541  AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 600
             I+INSAYT+KILPPEKEG LPRQVGNKTEC LLGFV DLKQDY+ VR+++PEEKLYKVY
Sbjct: 507  GISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVY 566

Query: 601  TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 660
            TFNSVRKSMSTVI+ P+  FRMYSKGASEI+L+KC +IL+  GE   F+ +DRD+MV+ V
Sbjct: 567  TFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTV 626

Query: 661  IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 720
            IEPMACDGLRTIC+AYRDF  + EP WDNEN+IL ELTCI VVGIEDPVRPEVP+AI KC
Sbjct: 627  IEPMACDGLRTICIAYRDFDDT-EPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKC 685

Query: 721  QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 780
            ++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEKGE+EQE++DK
Sbjct: 686  KQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDK 745

Query: 781  IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 840
            IWPKLRVLARSSPTDKHTLVKGIIDST  E RQVVAVTGDGTNDGPALKKADVGFAMGIA
Sbjct: 746  IWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIA 805

Query: 841  GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 900
            GTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
Sbjct: 806  GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 865

Query: 901  QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 960
            QDSPLKAVQMLWVNLIMDTFASLALATEPPTE+LL R+PYGRNKPLISRTMMKNILGHA 
Sbjct: 866  QDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAF 925

Query: 961  YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 1020
            YQL +IF L+F GEK F IDSGR APLHSPPS+HYTI+FNTFV+MQLFNEIN+RKIHGE+
Sbjct: 926  YQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNEINSRKIHGEK 985

Query: 1021 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1080
            NVF GI+RN IFC++VLGTF  QI IV+FGGKPFSC+ L L QW+WC+FIG+GEL+WGQ 
Sbjct: 986  NVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGIGELLWGQF 1045

Query: 1081 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1140
            I+ IPT  LKFLKEAG  T KEEI ++   E ++EIDHAE ELRRGQILWFRGLNRIQTQ
Sbjct: 1046 ISAIPTRSLKFLKEAGHGTTKEEITKDA--EGLDEIDHAEMELRRGQILWFRGLNRIQTQ 1103

Query: 1141 IRVVKAFRSSLYEGLEKPESRTSIHNFMAHPEFRIEDSQPHIPLIDDTDLEEDAALKQNS 1200
            I+VVKAF SSL+E ++KP ++ SIH+FM HPEF IE+  P  PL+D+ +       ++N 
Sbjct: 1104 IKVVKAFHSSLHESIQKPYNQKSIHSFMTHPEFAIEEELPRTPLLDEEE-------EENP 1156

Query: 1201 SPPSSLNKNNSAIDSGINLTTDTSKSATSSS------PGSPIHSLETSL 1243
               S        +D  +    +T+ +A   +        S + SLETS+
Sbjct: 1157 DKASKFGTRVLLLDGEVTPYANTNNNAVDCNQVQLPQSDSSLQSLETSV 1205


>gi|48255959 plasma membrane calcium ATPase 4 isoform 4a [Homo
            sapiens]
          Length = 1170

 Score = 1714 bits (4440), Expect = 0.0
 Identities = 865/1149 (75%), Positives = 971/1149 (84%), Gaps = 40/1149 (3%)

Query: 4    MTN-SDFYSKNQRNESSHGGEFGCTMEELRSLMELRGTEAVVKIKETYGDTEAICRRLKT 62
            MTN SD          S  G+FGCT+ ELR LMELR  +A+ +I   YG  + +C RLKT
Sbjct: 1    MTNPSDRVLPANSMAESREGDFGCTVMELRKLMELRSRDALTQINVHYGGVQNLCSRLKT 60

Query: 63   SPVEGLPGTAPDLEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLS 122
            SPVEGL G   DLEKR+Q+FG N IPPKKPKTFL+LVWEALQDVTLIILEIAAIISL LS
Sbjct: 61   SPVEGLSGNPADLEKRRQVFGHNVIPPKKPKTFLELVWEALQDVTLIILEIAAIISLVLS 120

Query: 123  FYHPPGEGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGL 182
            FY P GE NE C       EDE EA+AGWIEGAAIL SVI VVLVTAFNDWSKEKQFRGL
Sbjct: 121  FYRPAGEENELCGQVATTPEDENEAQAGWIEGAAILFSVIIVVLVTAFNDWSKEKQFRGL 180

Query: 183  QSRIEQEQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLT 242
            Q RIEQEQKF+++R GQ++Q+PVAEIVVGDIAQVKYGDLLPADG+ IQGNDLKIDESSLT
Sbjct: 181  QCRIEQEQKFSIIRNGQLIQLPVAEIVVGDIAQVKYGDLLPADGILIQGNDLKIDESSLT 240

Query: 243  GESDQVRKSVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
            GESD V+KS+DKDPMLLSGTHVMEGSGRM+VTAVGVNSQTGII TLLG   ++E +K KK
Sbjct: 241  GESDHVKKSLDKDPMLLSGTHVMEGSGRMVVTAVGVNSQTGIILTLLGVNEDDEGEKKKK 300

Query: 303  GVKKGDGLQLPAADGAAASNAADSANASLVNGKMQDGNVDASQSKAKQQDGAAAMEMQPL 362
            G K+G                                 V  +++KAK QDG A +E+QPL
Sbjct: 301  GKKQG---------------------------------VPENRNKAKTQDGVA-LEIQPL 326

Query: 363  KSAEGGDAD--DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDT 420
             S EG D +  D+K   + KKEKSVLQGKLT+LAVQIGKAGL+MSA+TV IL+LYF +D 
Sbjct: 327  NSQEGIDNEEKDKKAVKVPKKEKSVLQGKLTRLAVQIGKAGLLMSALTVFILILYFVIDN 386

Query: 421  FVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 480
            FV+N++PWLPECTP+Y+QYFVKFFIIG+TVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL
Sbjct: 387  FVINRRPWLPECTPIYIQYFVKFFIIGITVLVVAVPEGLPLAVTISLAYSVKKMMKDNNL 446

Query: 481  VRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLIN 540
            VRHLDACETMGNATAICSDKTGTLT NRMTVVQAY+G +HY++IP P     K ++L++N
Sbjct: 447  VRHLDACETMGNATAICSDKTGTLTMNRMTVVQAYIGGIHYRQIPSPDVFLPKVLDLIVN 506

Query: 541  AIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVY 600
             I+INSAYT+KILPPEKEG LPRQVGNKTEC LLGFV DLKQDY+ VR+++PEEKLYKVY
Sbjct: 507  GISINSAYTSKILPPEKEGGLPRQVGNKTECALLGFVTDLKQDYQAVRNEVPEEKLYKVY 566

Query: 601  TFNSVRKSMSTVIKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKV 660
            TFNSVRKSMSTVI+ P+  FRMYSKGASEI+L+KC +IL+  GE   F+ +DRD+MV+ V
Sbjct: 567  TFNSVRKSMSTVIRNPNGGFRMYSKGASEIILRKCNRILDRKGEAVPFKNKDRDDMVRTV 626

Query: 661  IEPMACDGLRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKC 720
            IEPMACDGLRTIC+AYRDF  + EP WDNEN+IL ELTCI VVGIEDPVRPEVP+AI KC
Sbjct: 627  IEPMACDGLRTICIAYRDFDDT-EPSWDNENEILTELTCIAVVGIEDPVRPEVPDAIAKC 685

Query: 721  QRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDK 780
            ++AGITVRMVTGDNINTARAIA KCGI+ PG+DFLCLEGKEFNR IRNEKGE+EQE++DK
Sbjct: 686  KQAGITVRMVTGDNINTARAIATKCGILTPGDDFLCLEGKEFNRLIRNEKGEVEQEKLDK 745

Query: 781  IWPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIA 840
            IWPKLRVLARSSPTDKHTLVKGIIDST  E RQVVAVTGDGTNDGPALKKADVGFAMGIA
Sbjct: 746  IWPKLRVLARSSPTDKHTLVKGIIDSTVGEHRQVVAVTGDGTNDGPALKKADVGFAMGIA 805

Query: 841  GTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 900
            GTDVAKEASDIILTDDNF+SIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT
Sbjct: 806  GTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACIT 865

Query: 901  QDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAV 960
            QDSPLKAVQMLWVNLIMDTFASLALATEPPTE+LL R+PYGRNKPLISRTMMKNILGHA 
Sbjct: 866  QDSPLKAVQMLWVNLIMDTFASLALATEPPTESLLKRRPYGRNKPLISRTMMKNILGHAF 925

Query: 961  YQLALIFTLLFVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGER 1020
            YQL +IF L+F GEK F IDSGR APLHSPPS+HYTI+FNTFV+MQLFNEIN+RKIHGE+
Sbjct: 926  YQLIVIFILVFAGEKFFDIDSGRKAPLHSPPSQHYTIVFNTFVLMQLFNEINSRKIHGEK 985

Query: 1021 NVFDGIFRNPIFCTIVLGTFAIQIVIVQFGGKPFSCSPLQLDQWMWCIFIGLGELVWGQV 1080
            NVF GI+RN IFC++VLGTF  QI IV+FGGKPFSC+ L L QW+WC+FIG+GEL+WGQ 
Sbjct: 986  NVFSGIYRNIIFCSVVLGTFICQIFIVEFGGKPFSCTSLSLSQWLWCLFIGIGELLWGQF 1045

Query: 1081 IATIPTSRLKFLKEAGRLTQKEEIPEEELNEDVEEIDHAERELRRGQILWFRGLNRIQTQ 1140
            I+ IPT  LKFLKEAG  T KEEI ++   E ++EIDHAE ELRRGQILWFRGLNRIQTQ
Sbjct: 1046 ISAIPTRSLKFLKEAGHGTTKEEITKDA--EGLDEIDHAEMELRRGQILWFRGLNRIQTQ 1103

Query: 1141 IRVVKAFRS 1149
            I V+  F++
Sbjct: 1104 IDVINTFQT 1112


>gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens]
          Length = 939

 Score =  263 bits (671), Expect = 1e-69
 Identities = 194/670 (28%), Positives = 335/670 (50%), Gaps = 71/670 (10%)

Query: 441  VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 500
            ++ F I V++ V A+PEGLP+ VT++LA  V +M+K   +V+ L   ET+G    ICSDK
Sbjct: 292  LEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDK 351

Query: 501  TGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 560
            TGTLT N MTV   +  D  + E+        +  E++++   ++  Y   +    + G 
Sbjct: 352  TGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVEAGC 409

Query: 561  LPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKSMST 611
            +           +G  TE  L+   + +  D       + ++ + K  Y F+S +K M+ 
Sbjct: 410  VCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKWMAV 463

Query: 612  VIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDG 668
                  +  R    + KGA E V+K C       G+      + RD   ++    M   G
Sbjct: 464  KCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MGSAG 521

Query: 669  LRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVR 728
            LR + +A     S PE         L +LT + +VGI DP R  V EA+     +G++++
Sbjct: 522  LRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIK 567

Query: 729  MVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVL 788
            M+TGD+  TA AIA + G+         + G+E +         ++ +++ +I PK+ V 
Sbjct: 568  MITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKVAVF 617

Query: 789  ARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEA 848
             R+SP  K  ++K +      +   VVA+TGDG ND  ALK AD+G AMG  GTDV KEA
Sbjct: 618  YRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672

Query: 849  SDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAV 908
            +D+IL DD+F +I+ A+  G+ +Y++I  F++FQL+ ++ A+ +      +   +PL A+
Sbjct: 673  ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732

Query: 909  QMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFT 968
            Q+LW+N+IMD   + +L  EP  + ++ + P      ++++ ++  IL   V  + ++  
Sbjct: 733  QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIIIVCG 789

Query: 969  LLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFD-G 1025
             LFV   E    + + R+           T+ F  FV   +FN +++R     ++VF+ G
Sbjct: 790  TLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVFEIG 837

Query: 1026 IFRNPIFCTIVLGTFAIQIVIVQFG--GKPFSCSPLQLDQWMWCIFIGLGELVWGQVIAT 1083
            +  N +FC  VLG+   Q++++ F    K F    L +   ++ + +     +  ++I  
Sbjct: 838  LCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKK 897

Query: 1084 IPTSRLKFLK 1093
            +  SR K  K
Sbjct: 898  VERSREKIQK 907



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 14/151 (9%)

Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
           +  +I ++++ VV V    ++  EK    L   +  E     VR G++      ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159

Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDP------------MLLS 260
              +  GD +PAD    +  DL IDESSLTGE+    K     P            +   
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219

Query: 261 GTHVMEGSGRMLVTAVGVNSQTGIIFTLLGA 291
           GT V  G  + +V   G NS+ G +F ++ A
Sbjct: 220 GTLVRCGKAKGVVIGTGENSEFGEVFKMMQA 250


>gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens]
          Length = 949

 Score =  263 bits (671), Expect = 1e-69
 Identities = 194/670 (28%), Positives = 335/670 (50%), Gaps = 71/670 (10%)

Query: 441  VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 500
            ++ F I V++ V A+PEGLP+ VT++LA  V +M+K   +V+ L   ET+G    ICSDK
Sbjct: 292  LEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDK 351

Query: 501  TGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 560
            TGTLT N MTV   +  D  + E+        +  E++++   ++  Y   +    + G 
Sbjct: 352  TGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVEAGC 409

Query: 561  LPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKSMST 611
            +           +G  TE  L+   + +  D       + ++ + K  Y F+S +K M+ 
Sbjct: 410  VCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKWMAV 463

Query: 612  VIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDG 668
                  +  R    + KGA E V+K C       G+      + RD   ++    M   G
Sbjct: 464  KCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MGSAG 521

Query: 669  LRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVR 728
            LR + +A     S PE         L +LT + +VGI DP R  V EA+     +G++++
Sbjct: 522  LRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIK 567

Query: 729  MVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVL 788
            M+TGD+  TA AIA + G+         + G+E +         ++ +++ +I PK+ V 
Sbjct: 568  MITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKVAVF 617

Query: 789  ARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEA 848
             R+SP  K  ++K +      +   VVA+TGDG ND  ALK AD+G AMG  GTDV KEA
Sbjct: 618  YRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672

Query: 849  SDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAV 908
            +D+IL DD+F +I+ A+  G+ +Y++I  F++FQL+ ++ A+ +      +   +PL A+
Sbjct: 673  ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732

Query: 909  QMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFT 968
            Q+LW+N+IMD   + +L  EP  + ++ + P      ++++ ++  IL   V  + ++  
Sbjct: 733  QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIIIVCG 789

Query: 969  LLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFD-G 1025
             LFV   E    + + R+           T+ F  FV   +FN +++R     ++VF+ G
Sbjct: 790  TLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVFEIG 837

Query: 1026 IFRNPIFCTIVLGTFAIQIVIVQFG--GKPFSCSPLQLDQWMWCIFIGLGELVWGQVIAT 1083
            +  N +FC  VLG+   Q++++ F    K F    L +   ++ + +     +  ++I  
Sbjct: 838  LCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKK 897

Query: 1084 IPTSRLKFLK 1093
            +  SR K  K
Sbjct: 898  VERSREKIQK 907



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 14/151 (9%)

Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
           +  +I ++++ VV V    ++  EK    L   +  E     VR G++      ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159

Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDP------------MLLS 260
              +  GD +PAD    +  DL IDESSLTGE+    K     P            +   
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219

Query: 261 GTHVMEGSGRMLVTAVGVNSQTGIIFTLLGA 291
           GT V  G  + +V   G NS+ G +F ++ A
Sbjct: 220 GTLVRCGKAKGVVIGTGENSEFGEVFKMMQA 250


>gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens]
          Length = 919

 Score =  263 bits (671), Expect = 1e-69
 Identities = 194/670 (28%), Positives = 335/670 (50%), Gaps = 71/670 (10%)

Query: 441  VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 500
            ++ F I V++ V A+PEGLP+ VT++LA  V +M+K   +V+ L   ET+G    ICSDK
Sbjct: 292  LEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDK 351

Query: 501  TGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 560
            TGTLT N MTV   +  D  + E+        +  E++++   ++  Y   +    + G 
Sbjct: 352  TGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVEAGC 409

Query: 561  LPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKSMST 611
            +           +G  TE  L+   + +  D       + ++ + K  Y F+S +K M+ 
Sbjct: 410  VCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKWMAV 463

Query: 612  VIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDG 668
                  +  R    + KGA E V+K C       G+      + RD   ++    M   G
Sbjct: 464  KCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MGSAG 521

Query: 669  LRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVR 728
            LR + +A     S PE         L +LT + +VGI DP R  V EA+     +G++++
Sbjct: 522  LRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIK 567

Query: 729  MVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVL 788
            M+TGD+  TA AIA + G+         + G+E +         ++ +++ +I PK+ V 
Sbjct: 568  MITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKVAVF 617

Query: 789  ARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEA 848
             R+SP  K  ++K +      +   VVA+TGDG ND  ALK AD+G AMG  GTDV KEA
Sbjct: 618  YRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672

Query: 849  SDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAV 908
            +D+IL DD+F +I+ A+  G+ +Y++I  F++FQL+ ++ A+ +      +   +PL A+
Sbjct: 673  ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732

Query: 909  QMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFT 968
            Q+LW+N+IMD   + +L  EP  + ++ + P      ++++ ++  IL   V  + ++  
Sbjct: 733  QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIIIVCG 789

Query: 969  LLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFD-G 1025
             LFV   E    + + R+           T+ F  FV   +FN +++R     ++VF+ G
Sbjct: 790  TLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVFEIG 837

Query: 1026 IFRNPIFCTIVLGTFAIQIVIVQFG--GKPFSCSPLQLDQWMWCIFIGLGELVWGQVIAT 1083
            +  N +FC  VLG+   Q++++ F    K F    L +   ++ + +     +  ++I  
Sbjct: 838  LCSNRMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVAEIIKK 897

Query: 1084 IPTSRLKFLK 1093
            +  SR K  K
Sbjct: 898  VERSREKIQK 907



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 14/151 (9%)

Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
           +  +I ++++ VV V    ++  EK    L   +  E     VR G++      ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159

Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDP------------MLLS 260
              +  GD +PAD    +  DL IDESSLTGE+    K     P            +   
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219

Query: 261 GTHVMEGSGRMLVTAVGVNSQTGIIFTLLGA 291
           GT V  G  + +V   G NS+ G +F ++ A
Sbjct: 220 GTLVRCGKAKGVVIGTGENSEFGEVFKMMQA 250


>gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens]
          Length = 888

 Score =  259 bits (663), Expect = 9e-69
 Identities = 186/624 (29%), Positives = 318/624 (50%), Gaps = 69/624 (11%)

Query: 441  VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 500
            ++ F I V++ V A+PEGLP+ VT++LA  V +M+K   +V+ L   ET+G    ICSDK
Sbjct: 292  LEMFTISVSLAVAAIPEGLPIVVTVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDK 351

Query: 501  TGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 560
            TGTLT N MTV   +  D  + E+        +  E++++   ++  Y   +    + G 
Sbjct: 352  TGTLTKNEMTVTHIFTSDGLHAEVTGVGY--NQFGEVIVDGDVVHGFYNPAVSRIVEAGC 409

Query: 561  LPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKV-YTFNSVRKSMST 611
            +           +G  TE  L+   + +  D       + ++ + K  Y F+S +K M+ 
Sbjct: 410  VCNDAVIRNNTLMGKPTEGALIALAMKMGLD------GLQQDYIRKAEYPFSSEQKWMAV 463

Query: 612  VIKLPDESFR---MYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDG 668
                  +  R    + KGA E V+K C       G+      + RD   ++    M   G
Sbjct: 464  KCVHRTQQDRPEICFMKGAYEQVIKYCTTY-QSKGQTLTLTQQQRDVYQQEKAR-MGSAG 521

Query: 669  LRTICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVR 728
            LR + +A     S PE         L +LT + +VGI DP R  V EA+     +G++++
Sbjct: 522  LRVLALA-----SGPE---------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIK 567

Query: 729  MVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVL 788
            M+TGD+  TA AIA + G+         + G+E +         ++ +++ +I PK+ V 
Sbjct: 568  MITGDSQETAVAIASRLGLYSKTSQ--SVSGEEIDA--------MDVQQLSQIVPKVAVF 617

Query: 789  ARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEA 848
             R+SP  K  ++K +      +   VVA+TGDG ND  ALK AD+G AMG  GTDV KEA
Sbjct: 618  YRASPRHKMKIIKSL-----QKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEA 672

Query: 849  SDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAV 908
            +D+IL DD+F +I+ A+  G+ +Y++I  F++FQL+ ++ A+ +      +   +PL A+
Sbjct: 673  ADMILVDDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAM 732

Query: 909  QMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFT 968
            Q+LW+N+IMD   + +L  EP  + ++ + P      ++++ ++  IL   V  + ++  
Sbjct: 733  QILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKIL---VSSIIIVCG 789

Query: 969  LLFV--GEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFD-G 1025
             LFV   E    + + R+           T+ F  FV   +FN +++R     ++VF+ G
Sbjct: 790  TLFVFWRELRDNVITPRDT----------TMTFTCFVFFDMFNALSSRS--QTKSVFEIG 837

Query: 1026 IFRNPIFCTIVLGTFAIQIVIVQF 1049
            +  N +FC  VLG+   Q++++ F
Sbjct: 838  LCSNRMFCYAVLGSIMGQLLVIYF 861



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 43/151 (28%), Positives = 67/151 (44%), Gaps = 14/151 (9%)

Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
           +  +I ++++ VV V    ++  EK    L   +  E     VR G++      ++V GD
Sbjct: 102 DAVSITVAILIVVTVAFVQEYRSEKSLEELSKLVPPECH--CVREGKLEHTLARDLVPGD 159

Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDKDP------------MLLS 260
              +  GD +PAD    +  DL IDESSLTGE+    K     P            +   
Sbjct: 160 TVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTPCSKVTAPQPAATNGDLASRSNIAFM 219

Query: 261 GTHVMEGSGRMLVTAVGVNSQTGIIFTLLGA 291
           GT V  G  + +V   G NS+ G +F ++ A
Sbjct: 220 GTLVRCGKAKGVVIGTGENSEFGEVFKMMQA 250


>gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo
            sapiens]
          Length = 946

 Score =  256 bits (653), Expect = 1e-67
 Identities = 196/618 (31%), Positives = 306/618 (49%), Gaps = 59/618 (9%)

Query: 441  VKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDK 500
            +  F IGV++ V A+PEGLP+ V ++L   V +M K   +V+ L   ET+G  + +CSDK
Sbjct: 321  LSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVLCSDK 380

Query: 501  TGTLTTNRMTVVQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 560
            TGTLT N MTV Q    D    E+         T+ LL +   I       +    + G 
Sbjct: 381  TGTLTANEMTVTQLVTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVSVGKLVEAGC 440

Query: 561  LPRQ--------VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTV 612
            +           +G  TE  L+   L +K D   +++    +K      F+S +K M+  
Sbjct: 441  VANNAVIRKNAVMGQPTEGALMA--LAMKMDLSDIKNSYIRKK---EIPFSSEQKWMAVK 495

Query: 613  --IKLPDESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLR 670
              +K  D+    + KGA E V++ C    NG G P    P+ R   +++  + M   GLR
Sbjct: 496  CSLKTEDQEDIYFMKGALEEVIRYCTMYNNG-GIPLPLTPQQRSFCLQEE-KRMGSLGLR 553

Query: 671  TICVAYRDFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMV 730
             + +A     S PE         L  LT + +VGI DP R  V EA++    +G++V+M+
Sbjct: 554  VLALA-----SGPE---------LGRLTFLGLVGIIDPPRVGVKEAVQVLSESGVSVKMI 599

Query: 731  TGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLAR 790
            TGD + TA AI    G+ +       + G+E +     EKGE+  +R+ K+     V  R
Sbjct: 600  TGDALETALAIGRNIGLCNG--KLQAMSGEEVDSV---EKGELA-DRVGKV----SVFFR 649

Query: 791  SSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASD 850
            +SP  K  ++K +      E   +VA+TGDG ND  ALK AD+G AMG  GTDV+KEA++
Sbjct: 650  TSPKHKLKIIKAL-----QESGAIVAMTGDGVNDAVALKSADIGIAMGQTGTDVSKEAAN 704

Query: 851  IILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQM 910
            +IL DD+FS+I+ AV  G+ ++ +I  F++FQL+ ++ A+ +          SPL A+Q+
Sbjct: 705  MILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQLSTSISALSLITLSTVFNLPSPLNAMQI 764

Query: 911  LWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTLL 970
            LW+N+IMD   + +L  EP  +    + P      ++SR ++  IL  A     +I   L
Sbjct: 765  LWINIIMDGPPAQSLGVEPVDKDAFRQPPRSVRDTILSRALILKILMSAA---IIISGTL 821

Query: 971  FVGEKMFQIDSGRNAPLHSPPSEHYTIIFNTFVMMQLFNEINARKIHGERNVFD-GIFRN 1029
            F+  K    D        +      T+ F  FV   LFN +  R     + +F+ G  RN
Sbjct: 822  FIFWKEMPED-------RASTPRTTTMTFTCFVFFDLFNALTCRS--QTKLIFEIGFLRN 872

Query: 1030 PIFCTIVLGTFAIQIVIV 1047
             +F   VLG+   Q+ ++
Sbjct: 873  HMFLYSVLGSILGQLAVI 890



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 42/149 (28%), Positives = 70/149 (46%), Gaps = 12/149 (8%)

Query: 153 EGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAGQVVQIPVAEIVVGD 212
           +  +I  +V+ VV V    ++  EK    L   +  E     +R G++  +   E+V GD
Sbjct: 133 DAVSIATAVLVVVTVAFIQEYRSEKSLEELTKMVPPE--CNCLREGKLQHLLARELVPGD 190

Query: 213 IAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKS----------VDKDPMLLSGT 262
           +  +  GD +PAD    +  DL +DESS TGE++   K+               ++  GT
Sbjct: 191 VVSLSIGDRIPADIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGT 250

Query: 263 HVMEGSGRMLVTAVGVNSQTGIIFTLLGA 291
            V  G G+ +V   G +SQ G +F ++ A
Sbjct: 251 LVQYGRGQGVVIGTGESSQFGEVFKMMQA 279


>gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo
           sapiens]
          Length = 997

 Score =  249 bits (635), Expect = 2e-65
 Identities = 257/938 (27%), Positives = 405/938 (43%), Gaps = 175/938 (18%)

Query: 75  LEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGC 134
           ++K K+ +G N +P ++ KT L+LV E  +D+ + IL +AA IS  L+++          
Sbjct: 29  VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF---------- 78

Query: 135 ATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 194
                  E+  E    ++E   ILL ++   +V     W +      +++  E E +   
Sbjct: 79  -------EEGEETITAFVEPFVILLILVANAIVGV---WQERNAENAIEALKEYEPEM-- 126

Query: 195 VRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDK 254
              G+V +     +      ++K  D++P D + I   D    +  LT       +    
Sbjct: 127 ---GKVYRQDRKSV-----QRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRV--- 175

Query: 255 DPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGVKKGDGLQLPA 314
           D  +L+G             +V V   T  +              D + V +     L +
Sbjct: 176 DQSILTGE------------SVSVIKHTDPV-------------PDPRAVNQDKKNMLFS 210

Query: 315 ADGAAASNAADSANASLVN---GKMQDGNVDASQSKAKQQDGAAAMEMQPLKSAEGGDAD 371
               AA  A     A+ VN   GK++D  V   Q                          
Sbjct: 211 GTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ-------------------------- 244

Query: 372 DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPE 431
                     E++ LQ KL +   Q+ K   V+S I + + ++        V+   W   
Sbjct: 245 ----------ERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSW--- 288

Query: 432 CTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMG 491
                ++  + +F I V + V A+PEGLP  +T  LA   ++M K N +VR L + ET+G
Sbjct: 289 -----IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLG 343

Query: 492 NATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDP 527
             + ICSDKTGTLTTN+M+V + ++                        G+VH  + P  
Sbjct: 344 CTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKP-- 401

Query: 528 SSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDL------- 580
             +N    + L+    I +      L   +   +  +VG  TE  L   V  +       
Sbjct: 402 --VNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTEL 459

Query: 581 ----KQDYEPVRSQMPEEKLYKVYT--FNSVRKSMSTVIKLPDESFR-----MYSKGASE 629
               K +     + + ++ + K +T  F+  RKSMS V   P++  R     M+ KGA E
Sbjct: 460 KGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPE 518

Query: 630 IVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMAC--DGLRTICVAYRDFPSSPEPDW 687
            V+ +C  I    G  +V       + +  VI       D LR + +A  D P   E   
Sbjct: 519 GVIDRCTHIR--VGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMH 576

Query: 688 --DNENDILNE--LTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAI 743
             D+ N I  E  LT +  VG+ DP R EV  +++ C++AGI V M+TGDN  TA AI  
Sbjct: 577 LEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICR 636

Query: 744 KCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI 803
           + GI    ED   +  K F  R   E  E+            R  AR  P+ K  +V+ +
Sbjct: 637 RIGIFGQDED---VTSKAFTGR---EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFL 690

Query: 804 IDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVK 863
                    ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNFS+IV 
Sbjct: 691 QSFD-----EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVA 744

Query: 864 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASL 923
           AV  GR +Y+++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + 
Sbjct: 745 AVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPAT 804

Query: 924 ALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
           AL   PP   ++ + P    +PLIS  +    L    Y
Sbjct: 805 ALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCY 842


>gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1
           [Homo sapiens]
          Length = 1042

 Score =  249 bits (635), Expect = 2e-65
 Identities = 257/938 (27%), Positives = 405/938 (43%), Gaps = 175/938 (18%)

Query: 75  LEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGC 134
           ++K K+ +G N +P ++ KT L+LV E  +D+ + IL +AA IS  L+++          
Sbjct: 29  VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF---------- 78

Query: 135 ATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 194
                  E+  E    ++E   ILL ++   +V     W +      +++  E E +   
Sbjct: 79  -------EEGEETITAFVEPFVILLILVANAIVGV---WQERNAENAIEALKEYEPEM-- 126

Query: 195 VRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDK 254
              G+V +     +      ++K  D++P D + I   D    +  LT       +    
Sbjct: 127 ---GKVYRQDRKSV-----QRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRV--- 175

Query: 255 DPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGVKKGDGLQLPA 314
           D  +L+G             +V V   T  +              D + V +     L +
Sbjct: 176 DQSILTGE------------SVSVIKHTDPV-------------PDPRAVNQDKKNMLFS 210

Query: 315 ADGAAASNAADSANASLVN---GKMQDGNVDASQSKAKQQDGAAAMEMQPLKSAEGGDAD 371
               AA  A     A+ VN   GK++D  V   Q                          
Sbjct: 211 GTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQ-------------------------- 244

Query: 372 DRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPE 431
                     E++ LQ KL +   Q+ K   V+S I + + ++        V+   W   
Sbjct: 245 ----------ERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSW--- 288

Query: 432 CTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMG 491
                ++  + +F I V + V A+PEGLP  +T  LA   ++M K N +VR L + ET+G
Sbjct: 289 -----IRGAIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLG 343

Query: 492 NATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDP 527
             + ICSDKTGTLTTN+M+V + ++                        G+VH  + P  
Sbjct: 344 CTSVICSDKTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKP-- 401

Query: 528 SSINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDL------- 580
             +N    + L+    I +      L   +   +  +VG  TE  L   V  +       
Sbjct: 402 --VNCHQYDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTEL 459

Query: 581 ----KQDYEPVRSQMPEEKLYKVYT--FNSVRKSMSTVIKLPDESFR-----MYSKGASE 629
               K +     + + ++ + K +T  F+  RKSMS V   P++  R     M+ KGA E
Sbjct: 460 KGLSKIERANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPE 518

Query: 630 IVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMAC--DGLRTICVAYRDFPSSPEPDW 687
            V+ +C  I    G  +V       + +  VI       D LR + +A  D P   E   
Sbjct: 519 GVIDRCTHIR--VGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMH 576

Query: 688 --DNENDILNE--LTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAI 743
             D+ N I  E  LT +  VG+ DP R EV  +++ C++AGI V M+TGDN  TA AI  
Sbjct: 577 LEDSANFIKYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICR 636

Query: 744 KCGIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGI 803
           + GI    ED   +  K F  R   E  E+            R  AR  P+ K  +V+ +
Sbjct: 637 RIGIFGQDED---VTSKAFTGR---EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFL 690

Query: 804 IDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVK 863
                    ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNFS+IV 
Sbjct: 691 QSFD-----EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVA 744

Query: 864 AVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASL 923
           AV  GR +Y+++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + 
Sbjct: 745 AVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPAT 804

Query: 924 ALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
           AL   PP   ++ + P    +PLIS  +    L    Y
Sbjct: 805 ALGFNPPDLDIMNKPPRNPKEPLISGWLFFRYLAIGCY 842


>gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens]
          Length = 1039

 Score =  248 bits (634), Expect = 2e-65
 Identities = 196/592 (33%), Positives = 303/592 (51%), Gaps = 70/592 (11%)

Query: 391 TKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTV 450
           T +A++I     +++ + V I +L+F +                V ++Y V   II +  
Sbjct: 297 TPIAIEIEHFVHIVAGVAVSIGILFFII---------------AVSLKYQVLDSIIFLIG 341

Query: 451 LVVA-VPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRM 509
           ++VA VPEGL   VT++L+ + K+M K N LV++L+A ET+G+ + ICSDKTGTLT NRM
Sbjct: 342 IIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVETLGSTSIICSDKTGTLTQNRM 401

Query: 510 TVV------QAYVGDV---HYKEIPDPSSINTKTMELLINAIAINSAYTTKILPPEKEGA 560
           TV       Q +V D    H  ++ D SS    ++  +I     N A   +  P ++   
Sbjct: 402 TVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKIITLC--NRA---EFKPGQENVP 456

Query: 561 LPRQ--VGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPD- 617
           + ++  +G+ +E  LL F   +  D   +R +    K+ ++  FNS  K   ++ ++ D 
Sbjct: 457 IMKKAVIGDASETALLKFSEVILGDVMEIRKR--NRKVAEI-PFNSTNKFQLSIHEMDDP 513

Query: 618 --ESFRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRT---- 671
             + F M  KGA E +L+KC  I+    E     P D+          M   GL      
Sbjct: 514 HGKRFLMVMKGAPERILEKCSTIMINGEE----HPLDKSTAKTFHTAYMELGGLGERVLG 569

Query: 672 ICVAYR---DFPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVR 728
            C  Y    +FP +   D D  N   + L  + ++ + DP R  VP+A+ KC+ AGI V 
Sbjct: 570 FCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTKCRSAGIKVI 629

Query: 729 MVTGDNINTARAIAIKCGIIHPGEDF-------LCLEGKEFNRRIRN-------EKGEIE 774
           MVTGD+  TA+AIA   GII    +        L +  ++ N+R          E  ++ 
Sbjct: 630 MVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVVTGMELKDMS 689

Query: 775 QERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKAD 832
            E++D+I    +  V AR+SP  K  +V+G        Q  VVAVTGDG ND PALKKAD
Sbjct: 690 SEQLDEILANYQEIVFARTSPQQKLIIVEGC-----QRQDAVVAVTGDGVNDSPALKKAD 744

Query: 833 VGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIV 892
           +G AMGIAG+D AK A+D++L DDNF+SIV  V  GR ++D++ K + + LT N+  +  
Sbjct: 745 IGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIAELCP 804

Query: 893 AFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNK 944
                 +    P+  + +L+++L  D   S+ALA E     ++ RKP  +NK
Sbjct: 805 FLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNK 856



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 41/143 (28%), Positives = 69/143 (48%), Gaps = 10/143 (6%)

Query: 164 VVLVTAFNDWSKEKQFRGLQSRIEQ--EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDL 221
           VV++T    + +E +   + S   +   Q+  V+R  +   IP  ++VVGDI +VK GD 
Sbjct: 154 VVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQLVVGDIVEVKGGDQ 213

Query: 222 LPADGLFIQGNDLKIDESSLTGESDQVRKS--------VDKDPMLLSGTHVMEGSGRMLV 273
           +PAD   +     ++D SSLTGES+   +S        ++   +    T  +EG+   +V
Sbjct: 214 IPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFYSTTCLEGTVTGMV 273

Query: 274 TAVGVNSQTGIIFTLLGAGGEEE 296
              G  +  G I +L    G E+
Sbjct: 274 INTGDRTIIGHIASLASGVGNEK 296


>gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo
           sapiens]
          Length = 999

 Score =  244 bits (623), Expect = 4e-64
 Identities = 197/636 (30%), Positives = 303/636 (47%), Gaps = 75/636 (11%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  + E++ LQ KL +   Q+  A   +S I V + V+         +   WL   
Sbjct: 236 RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   V +F I V + V A+PEGLP  +T  LA   ++M + N +VR L + ET+G 
Sbjct: 293 --------VYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDPS 528
            + ICSDKTGTLTTN+M+V + +V                        G+V   + P   
Sbjct: 345 TSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQP--- 401

Query: 529 SINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFV-------LDLK 581
            +     + L+    I +      L   +   +  +VG  TE  L   V        DL+
Sbjct: 402 -VRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQ 460

Query: 582 QDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS-----TVIKLPDESFRMYSKGASEI 630
                 R+     + ++ + K +T  F+  RKSMS     T      +  +M+ KGA E 
Sbjct: 461 ALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPES 520

Query: 631 VLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMACDGLRTICVAYRDFPSSPEP---- 685
           V+++C  +  G+       P  R++++ K+ +     D LR + +A RD P   E     
Sbjct: 521 VIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579

Query: 686 DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKC 745
           D         +LT +  VG+ DP RPEV   I +C +AGI V M+TGDN  TA AI  + 
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639

Query: 746 GIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
           GI    ED   + GK +  R   E  ++  E+  +     R  AR  P  K  +V+ +  
Sbjct: 640 GIFGDTED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF+SIV AV
Sbjct: 692 ---QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y ++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
              PP   ++ + P    + LIS  +    L   VY
Sbjct: 808 GFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 64/239 (26%), Positives = 116/239 (48%), Gaps = 34/239 (14%)

Query: 79  KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
           ++ +G N +P ++ K+  +LV E  +D+ + IL +AA++S  L+++              
Sbjct: 33  RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78

Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
              E+  E    ++E   I+L ++   +V  + + + E     L+    +  K  V+R+ 
Sbjct: 79  ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133

Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESDQVRK---- 250
           +  V +I   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V K    
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193

Query: 251 -------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
                  + DK  ML SGT++  G    +  A G++++ G I + + A   E     +K
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRK 252


>gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  244 bits (623), Expect = 4e-64
 Identities = 197/636 (30%), Positives = 303/636 (47%), Gaps = 75/636 (11%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  + E++ LQ KL +   Q+  A   +S I V + V+         +   WL   
Sbjct: 236 RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   V +F I V + V A+PEGLP  +T  LA   ++M + N +VR L + ET+G 
Sbjct: 293 --------VYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDPS 528
            + ICSDKTGTLTTN+M+V + +V                        G+V   + P   
Sbjct: 345 TSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQP--- 401

Query: 529 SINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFV-------LDLK 581
            +     + L+    I +      L   +   +  +VG  TE  L   V        DL+
Sbjct: 402 -VRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQ 460

Query: 582 QDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS-----TVIKLPDESFRMYSKGASEI 630
                 R+     + ++ + K +T  F+  RKSMS     T      +  +M+ KGA E 
Sbjct: 461 ALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPES 520

Query: 631 VLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMACDGLRTICVAYRDFPSSPEP---- 685
           V+++C  +  G+       P  R++++ K+ +     D LR + +A RD P   E     
Sbjct: 521 VIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579

Query: 686 DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKC 745
           D         +LT +  VG+ DP RPEV   I +C +AGI V M+TGDN  TA AI  + 
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639

Query: 746 GIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
           GI    ED   + GK +  R   E  ++  E+  +     R  AR  P  K  +V+ +  
Sbjct: 640 GIFGDTED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF+SIV AV
Sbjct: 692 ---QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y ++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
              PP   ++ + P    + LIS  +    L   VY
Sbjct: 808 GFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 64/239 (26%), Positives = 116/239 (48%), Gaps = 34/239 (14%)

Query: 79  KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
           ++ +G N +P ++ K+  +LV E  +D+ + IL +AA++S  L+++              
Sbjct: 33  RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78

Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
              E+  E    ++E   I+L ++   +V  + + + E     L+    +  K  V+R+ 
Sbjct: 79  ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133

Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESDQVRK---- 250
           +  V +I   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V K    
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193

Query: 251 -------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
                  + DK  ML SGT++  G    +  A G++++ G I + + A   E     +K
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRK 252


>gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo
           sapiens]
          Length = 998

 Score =  244 bits (623), Expect = 4e-64
 Identities = 197/636 (30%), Positives = 303/636 (47%), Gaps = 75/636 (11%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  + E++ LQ KL +   Q+  A   +S I V + V+         +   WL   
Sbjct: 236 RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   V +F I V + V A+PEGLP  +T  LA   ++M + N +VR L + ET+G 
Sbjct: 293 --------VYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDPS 528
            + ICSDKTGTLTTN+M+V + +V                        G+V   + P   
Sbjct: 345 TSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQP--- 401

Query: 529 SINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFV-------LDLK 581
            +     + L+    I +      L   +   +  +VG  TE  L   V        DL+
Sbjct: 402 -VRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQ 460

Query: 582 QDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS-----TVIKLPDESFRMYSKGASEI 630
                 R+     + ++ + K +T  F+  RKSMS     T      +  +M+ KGA E 
Sbjct: 461 ALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPES 520

Query: 631 VLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMACDGLRTICVAYRDFPSSPEP---- 685
           V+++C  +  G+       P  R++++ K+ +     D LR + +A RD P   E     
Sbjct: 521 VIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579

Query: 686 DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKC 745
           D         +LT +  VG+ DP RPEV   I +C +AGI V M+TGDN  TA AI  + 
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639

Query: 746 GIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
           GI    ED   + GK +  R   E  ++  E+  +     R  AR  P  K  +V+ +  
Sbjct: 640 GIFGDTED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF+SIV AV
Sbjct: 692 ---QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y ++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
              PP   ++ + P    + LIS  +    L   VY
Sbjct: 808 GFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 64/239 (26%), Positives = 116/239 (48%), Gaps = 34/239 (14%)

Query: 79  KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
           ++ +G N +P ++ K+  +LV E  +D+ + IL +AA++S  L+++              
Sbjct: 33  RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78

Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
              E+  E    ++E   I+L ++   +V  + + + E     L+    +  K  V+R+ 
Sbjct: 79  ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133

Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESDQVRK---- 250
           +  V +I   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V K    
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193

Query: 251 -------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
                  + DK  ML SGT++  G    +  A G++++ G I + + A   E     +K
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRK 252


>gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo
           sapiens]
          Length = 1029

 Score =  244 bits (623), Expect = 4e-64
 Identities = 197/636 (30%), Positives = 303/636 (47%), Gaps = 75/636 (11%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  + E++ LQ KL +   Q+  A   +S I V + V+         +   WL   
Sbjct: 236 RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   V +F I V + V A+PEGLP  +T  LA   ++M + N +VR L + ET+G 
Sbjct: 293 --------VYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDPS 528
            + ICSDKTGTLTTN+M+V + +V                        G+V   + P   
Sbjct: 345 TSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQP--- 401

Query: 529 SINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFV-------LDLK 581
            +     + L+    I +      L   +   +  +VG  TE  L   V        DL+
Sbjct: 402 -VRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQ 460

Query: 582 QDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS-----TVIKLPDESFRMYSKGASEI 630
                 R+     + ++ + K +T  F+  RKSMS     T      +  +M+ KGA E 
Sbjct: 461 ALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPES 520

Query: 631 VLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMACDGLRTICVAYRDFPSSPEP---- 685
           V+++C  +  G+       P  R++++ K+ +     D LR + +A RD P   E     
Sbjct: 521 VIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579

Query: 686 DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKC 745
           D         +LT +  VG+ DP RPEV   I +C +AGI V M+TGDN  TA AI  + 
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639

Query: 746 GIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
           GI    ED   + GK +  R   E  ++  E+  +     R  AR  P  K  +V+ +  
Sbjct: 640 GIFGDTED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF+SIV AV
Sbjct: 692 ---QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y ++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
              PP   ++ + P    + LIS  +    L   VY
Sbjct: 808 GFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 64/239 (26%), Positives = 116/239 (48%), Gaps = 34/239 (14%)

Query: 79  KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
           ++ +G N +P ++ K+  +LV E  +D+ + IL +AA++S  L+++              
Sbjct: 33  RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78

Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
              E+  E    ++E   I+L ++   +V  + + + E     L+    +  K  V+R+ 
Sbjct: 79  ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133

Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESDQVRK---- 250
           +  V +I   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V K    
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193

Query: 251 -------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
                  + DK  ML SGT++  G    +  A G++++ G I + + A   E     +K
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRK 252


>gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo
           sapiens]
          Length = 1043

 Score =  244 bits (623), Expect = 4e-64
 Identities = 197/636 (30%), Positives = 303/636 (47%), Gaps = 75/636 (11%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  + E++ LQ KL +   Q+  A   +S I V + V+         +   WL   
Sbjct: 236 RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   V +F I V + V A+PEGLP  +T  LA   ++M + N +VR L + ET+G 
Sbjct: 293 --------VYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDPS 528
            + ICSDKTGTLTTN+M+V + +V                        G+V   + P   
Sbjct: 345 TSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQP--- 401

Query: 529 SINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFV-------LDLK 581
            +     + L+    I +      L   +   +  +VG  TE  L   V        DL+
Sbjct: 402 -VRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQ 460

Query: 582 QDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS-----TVIKLPDESFRMYSKGASEI 630
                 R+     + ++ + K +T  F+  RKSMS     T      +  +M+ KGA E 
Sbjct: 461 ALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPES 520

Query: 631 VLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMACDGLRTICVAYRDFPSSPEP---- 685
           V+++C  +  G+       P  R++++ K+ +     D LR + +A RD P   E     
Sbjct: 521 VIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579

Query: 686 DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKC 745
           D         +LT +  VG+ DP RPEV   I +C +AGI V M+TGDN  TA AI  + 
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639

Query: 746 GIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
           GI    ED   + GK +  R   E  ++  E+  +     R  AR  P  K  +V+ +  
Sbjct: 640 GIFGDTED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF+SIV AV
Sbjct: 692 ---QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y ++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
              PP   ++ + P    + LIS  +    L   VY
Sbjct: 808 GFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 64/239 (26%), Positives = 116/239 (48%), Gaps = 34/239 (14%)

Query: 79  KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
           ++ +G N +P ++ K+  +LV E  +D+ + IL +AA++S  L+++              
Sbjct: 33  RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78

Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
              E+  E    ++E   I+L ++   +V  + + + E     L+    +  K  V+R+ 
Sbjct: 79  ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133

Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESDQVRK---- 250
           +  V +I   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V K    
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193

Query: 251 -------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
                  + DK  ML SGT++  G    +  A G++++ G I + + A   E     +K
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRK 252


>gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo
           sapiens]
          Length = 1044

 Score =  244 bits (623), Expect = 4e-64
 Identities = 197/636 (30%), Positives = 303/636 (47%), Gaps = 75/636 (11%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  + E++ LQ KL +   Q+  A   +S I V + V+         +   WL   
Sbjct: 236 RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   V +F I V + V A+PEGLP  +T  LA   ++M + N +VR L + ET+G 
Sbjct: 293 --------VYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDPS 528
            + ICSDKTGTLTTN+M+V + +V                        G+V   + P   
Sbjct: 345 TSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQP--- 401

Query: 529 SINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFV-------LDLK 581
            +     + L+    I +      L   +   +  +VG  TE  L   V        DL+
Sbjct: 402 -VRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQ 460

Query: 582 QDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS-----TVIKLPDESFRMYSKGASEI 630
                 R+     + ++ + K +T  F+  RKSMS     T      +  +M+ KGA E 
Sbjct: 461 ALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPES 520

Query: 631 VLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMACDGLRTICVAYRDFPSSPEP---- 685
           V+++C  +  G+       P  R++++ K+ +     D LR + +A RD P   E     
Sbjct: 521 VIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579

Query: 686 DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKC 745
           D         +LT +  VG+ DP RPEV   I +C +AGI V M+TGDN  TA AI  + 
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639

Query: 746 GIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
           GI    ED   + GK +  R   E  ++  E+  +     R  AR  P  K  +V+ +  
Sbjct: 640 GIFGDTED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF+SIV AV
Sbjct: 692 ---QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y ++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
              PP   ++ + P    + LIS  +    L   VY
Sbjct: 808 GFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 64/239 (26%), Positives = 116/239 (48%), Gaps = 34/239 (14%)

Query: 79  KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
           ++ +G N +P ++ K+  +LV E  +D+ + IL +AA++S  L+++              
Sbjct: 33  RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78

Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
              E+  E    ++E   I+L ++   +V  + + + E     L+    +  K  V+R+ 
Sbjct: 79  ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133

Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESDQVRK---- 250
           +  V +I   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V K    
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193

Query: 251 -------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
                  + DK  ML SGT++  G    +  A G++++ G I + + A   E     +K
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRK 252


>gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo
           sapiens]
          Length = 1052

 Score =  244 bits (623), Expect = 4e-64
 Identities = 197/636 (30%), Positives = 303/636 (47%), Gaps = 75/636 (11%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  + E++ LQ KL +   Q+  A   +S I V + V+         +   WL   
Sbjct: 236 RSQMAAVEPERTPLQRKLDEFGRQLSHA---ISVICVAVWVINIGHFADPAHGGSWLRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   V +F I V + V A+PEGLP  +T  LA   ++M + N +VR L + ET+G 
Sbjct: 293 --------VYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDPS 528
            + ICSDKTGTLTTN+M+V + +V                        G+V   + P   
Sbjct: 345 TSVICSDKTGTLTTNQMSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQP--- 401

Query: 529 SINTKTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFV-------LDLK 581
            +     + L+    I +      L   +   +  +VG  TE  L   V        DL+
Sbjct: 402 -VRCGQFDGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQ 460

Query: 582 QDYEPVRS----QMPEEKLYKVYT--FNSVRKSMS-----TVIKLPDESFRMYSKGASEI 630
                 R+     + ++ + K +T  F+  RKSMS     T      +  +M+ KGA E 
Sbjct: 461 ALSRVERAGACNTVIKQLMRKEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPES 520

Query: 631 VLKKCCKILNGAGEPRVFRPRDRDEMVKKVIE-PMACDGLRTICVAYRDFPSSPEP---- 685
           V+++C  +  G+       P  R++++ K+ +     D LR + +A RD P   E     
Sbjct: 521 VIERCSSVRVGS-RTAPLTPTSREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELD 579

Query: 686 DWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKC 745
           D         +LT +  VG+ DP RPEV   I +C +AGI V M+TGDN  TA AI  + 
Sbjct: 580 DCSKFVQYETDLTFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRL 639

Query: 746 GIIHPGEDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
           GI    ED   + GK +  R   E  ++  E+  +     R  AR  P  K  +V+ +  
Sbjct: 640 GIFGDTED---VAGKAYTGR---EFDDLSPEQQRQACRTARCFARVEPAHKSRIVENL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK A++++L+DDNF+SIV AV
Sbjct: 692 ---QSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y ++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
              PP   ++ + P    + LIS  +    L   VY
Sbjct: 808 GFNPPDLDIMEKLPRSPREALISGWLFFRYLAIGVY 843



 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 64/239 (26%), Positives = 116/239 (48%), Gaps = 34/239 (14%)

Query: 79  KQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQ 138
           ++ +G N +P ++ K+  +LV E  +D+ + IL +AA++S  L+++              
Sbjct: 33  RERYGPNELPSEEGKSLWELVLEQFEDLLVRILLLAALVSFVLAWF-------------- 78

Query: 139 GGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTVVRAG 198
              E+  E    ++E   I+L ++   +V  + + + E     L+    +  K  V+R+ 
Sbjct: 79  ---EEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALKEYEPEMGK--VIRSD 133

Query: 199 Q--VVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESDQVRK---- 250
           +  V +I   +IV GDI +V  GD +PAD   + I+   L++D+S LTGES  V K    
Sbjct: 134 RKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILTGESVSVTKHTEA 193

Query: 251 -------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKK 302
                  + DK  ML SGT++  G    +  A G++++ G I + + A   E     +K
Sbjct: 194 IPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAAVEPERTPLQRK 252


>gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3
           [Homo sapiens]
          Length = 1015

 Score =  240 bits (613), Expect = 5e-63
 Identities = 198/630 (31%), Positives = 302/630 (47%), Gaps = 78/630 (12%)

Query: 380 KKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQY 439
           ++E++ LQ KL +   Q+ K   V+S I + + ++        V+   W        ++ 
Sbjct: 216 EQERTPLQQKLDEFGEQLSK---VISLICIAVWIINIGHFNDPVHGGSW--------IRG 264

Query: 440 FVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSD 499
            + +F I V + V A+PEGLP  +T  LA   ++M K N +VR L + ET+G  + ICSD
Sbjct: 265 AIYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSD 324

Query: 500 KTGTLTTNRMTVVQAYV------------------------GDVHYKEIPDPSSINTKTM 535
           KTGTLTTN+M+V + ++                        G+VH  + P    +N    
Sbjct: 325 KTGTLTTNQMSVCRMFILDRVEGDTCSLNEFTITGSTYAPIGEVHKDDKP----VNCHQY 380

Query: 536 ELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDL-----------KQDY 584
           + L+    I +      L   +   +  +VG  TE  L   V  +           K + 
Sbjct: 381 DGLVELATICALCNDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTELKGLSKIER 440

Query: 585 EPVRSQMPEEKLYKVYT--FNSVRKSMSTVIKLPDESFR-----MYSKGASEIVLKKCCK 637
               + + ++ + K +T  F+  RKSMS V   P++  R     M+ KGA E V+ +C  
Sbjct: 441 ANACNSVIKQLMKKEFTLEFSRDRKSMS-VYCTPNKPSRTSMSKMFVKGAPEGVIDRCTH 499

Query: 638 ILNGAGEPRVFRPRDRDEMVKKVIEPMAC--DGLRTICVAYRDFPSSPEPDW--DNENDI 693
           I    G  +V       + +  VI       D LR + +A  D P   E     D+ N I
Sbjct: 500 IR--VGSTKVPMTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFI 557

Query: 694 LNE--LTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPG 751
             E  LT +  VG+ DP R EV  +++ C++AGI V M+TGDN  TA AI  + GI    
Sbjct: 558 KYETNLTFVGCVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD 617

Query: 752 EDFLCLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIIDSTHTEQ 811
           ED   +  K F  R   E  E+            R  AR  P+ K  +V+ +        
Sbjct: 618 ED---VTSKAFTGR---EFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQSFD---- 667

Query: 812 RQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNV 871
            ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNFS+IV AV  GR +
Sbjct: 668 -EITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGRAI 725

Query: 872 YDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPT 931
           Y+++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL   PP 
Sbjct: 726 YNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNPPD 785

Query: 932 ETLLLRKPYGRNKPLISRTMMKNILGHAVY 961
             ++ + P    +PLIS  +    L    Y
Sbjct: 786 LDIMNKPPRNPKEPLISGWLFFRYLAIGCY 815



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 60/236 (25%), Positives = 106/236 (44%), Gaps = 31/236 (13%)

Query: 75  LEKRKQIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGC 134
           ++K K+ +G N +P ++ KT L+LV E  +D+ + IL +AA IS  L+++          
Sbjct: 29  VKKLKERWGSNELPAEEGKTLLELVIEQFEDLLVRILLLAACISFVLAWF---------- 78

Query: 135 ATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQEQKFTV 194
                  E+  E    ++E   ILL ++   +V  + + + E     L+    +  K   
Sbjct: 79  -------EEGEETITAFVEPFVILLILVANAIVGVWQERNAENAIEALKEYEPEMGKVYR 131

Query: 195 VRAGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVDK 254
                V +I   +IV GDI ++  G+ +      I+  D   D  ++         + DK
Sbjct: 132 QDRKSVQRIKAKDIVPGDIVEIA-GESVSV----IKHTDPVPDPRAV---------NQDK 177

Query: 255 DPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGVKKGDGL 310
             ML SGT++  G    +V A GVN++ G I   + A  +E     +K  + G+ L
Sbjct: 178 KNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQERTPLQQKLDEFGEQL 233


>gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b
           [Homo sapiens]
          Length = 994

 Score =  238 bits (608), Expect = 2e-62
 Identities = 198/623 (31%), Positives = 298/623 (47%), Gaps = 75/623 (12%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  +++K+ LQ KL +   Q+ K   V+S I V + ++        V+   W    
Sbjct: 236 RDQMAATEQDKTPLQQKLDEFGEQLSK---VISLICVAVWLINIGHFNDPVHGGSWFRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   + +F I V + V A+PEGLP  +T  LA   ++M K N +VR L + ET+G 
Sbjct: 293 --------IYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV-----GDV---------------HYKEIPDPSSINT 532
            + ICSDKTGTLTTN+M+V + ++     GD+                 + + +   +  
Sbjct: 345 TSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRP 404

Query: 533 KTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMP 592
              + L+    I +      L   +   +  +VG  TE  L   V  +      VRS   
Sbjct: 405 GQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSK 464

Query: 593 EEK-----------LYKVYT--FNSVRKSMSTVIKLPDESFR------MYSKGASEIVLK 633
            E+           + K +T  F+  RKSMS     P +S R      M+ KGA E V+ 
Sbjct: 465 VERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCS-PAKSSRAAVGNKMFVKGAPEGVID 523

Query: 634 KCCKILNGAGEPRVFRPRDRDEMVKKVIEPMAC--DGLRTICVAYRDFPSSPEP----DW 687
           +C  +    G  RV       E +  VI+      D LR + +A RD P   E     D 
Sbjct: 524 RCNYVR--VGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDS 581

Query: 688 DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGI 747
               +   +LT + VVG+ DP R EV  +I+ C+ AGI V M+TGDN  TA AI  + GI
Sbjct: 582 ARFLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGI 641

Query: 748 IHPGEDFL--CLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
               E+       G+EF+     E+ E  +             AR  P+ K  +V+ +  
Sbjct: 642 FGENEEVADRAYTGREFDDLPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNFS+IV AV
Sbjct: 692 ---QSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y+++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLIS 948
              PP   ++ R P    +PLIS
Sbjct: 808 GFNPPDLDIMDRPPRSPKEPLIS 830



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 74/255 (29%), Positives = 118/255 (46%), Gaps = 31/255 (12%)

Query: 70  GTAPDLEKRK-QIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPG 128
           G  PD  KR  + +G N +P ++ KT  +LV E  +D+ + IL +AA IS  L+++    
Sbjct: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF---- 78

Query: 129 EGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ 188
                        E+  E    ++E   ILL +I   +V  + + + E     L+    +
Sbjct: 79  -------------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPE 125

Query: 189 EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESD 246
             K        V +I   +IV GDI +V  GD +PAD   L I+   L++D+S LTGES 
Sbjct: 126 MGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESV 185

Query: 247 QVRK-----------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEE 295
            V K           + DK  ML SGT++  G    +V   GV ++ G I   + A  ++
Sbjct: 186 SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQD 245

Query: 296 EEKKDKKGVKKGDGL 310
           +    +K  + G+ L
Sbjct: 246 KTPLQQKLDEFGEQL 260


>gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a
           [Homo sapiens]
          Length = 1001

 Score =  238 bits (608), Expect = 2e-62
 Identities = 198/623 (31%), Positives = 298/623 (47%), Gaps = 75/623 (12%)

Query: 373 RKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVDTFVVNKKPWLPEC 432
           R + +  +++K+ LQ KL +   Q+ K   V+S I V + ++        V+   W    
Sbjct: 236 RDQMAATEQDKTPLQQKLDEFGEQLSK---VISLICVAVWLINIGHFNDPVHGGSWFRGA 292

Query: 433 TPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGN 492
                   + +F I V + V A+PEGLP  +T  LA   ++M K N +VR L + ET+G 
Sbjct: 293 --------IYYFKIAVALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGC 344

Query: 493 ATAICSDKTGTLTTNRMTVVQAYV-----GDV---------------HYKEIPDPSSINT 532
            + ICSDKTGTLTTN+M+V + ++     GD+                 + + +   +  
Sbjct: 345 TSVICSDKTGTLTTNQMSVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRP 404

Query: 533 KTMELLINAIAINSAYTTKILPPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMP 592
              + L+    I +      L   +   +  +VG  TE  L   V  +      VRS   
Sbjct: 405 GQYDGLVELATICALCNDSSLDFNEAKGVYEKVGEATETALTTLVEKMNVFNTDVRSLSK 464

Query: 593 EEK-----------LYKVYT--FNSVRKSMSTVIKLPDESFR------MYSKGASEIVLK 633
            E+           + K +T  F+  RKSMS     P +S R      M+ KGA E V+ 
Sbjct: 465 VERANACNSVIRQLMKKEFTLEFSRDRKSMSVYCS-PAKSSRAAVGNKMFVKGAPEGVID 523

Query: 634 KCCKILNGAGEPRVFRPRDRDEMVKKVIEPMAC--DGLRTICVAYRDFPSSPEP----DW 687
           +C  +    G  RV       E +  VI+      D LR + +A RD P   E     D 
Sbjct: 524 RCNYVR--VGTTRVPLTGPVKEKIMAVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDS 581

Query: 688 DNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGI 747
               +   +LT + VVG+ DP R EV  +I+ C+ AGI V M+TGDN  TA AI  + GI
Sbjct: 582 ARFLEYETDLTFVGVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGI 641

Query: 748 IHPGEDFL--CLEGKEFNRRIRNEKGEIEQERIDKIWPKLRVLARSSPTDKHTLVKGIID 805
               E+       G+EF+     E+ E  +             AR  P+ K  +V+ +  
Sbjct: 642 FGENEEVADRAYTGREFDDLPLAEQREACRRAC--------CFARVEPSHKSKIVEYL-- 691

Query: 806 STHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAV 865
                  ++ A+TGDG ND PALKKA++G AMG +GT VAK AS+++L DDNFS+IV AV
Sbjct: 692 ---QSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAV 747

Query: 866 MWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLAL 925
             GR +Y+++ +F+++ ++ NV  V+  F  A +     L  VQ+LWVNL+ D   + AL
Sbjct: 748 EEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATAL 807

Query: 926 ATEPPTETLLLRKPYGRNKPLIS 948
              PP   ++ R P    +PLIS
Sbjct: 808 GFNPPDLDIMDRPPRSPKEPLIS 830



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 74/255 (29%), Positives = 118/255 (46%), Gaps = 31/255 (12%)

Query: 70  GTAPDLEKRK-QIFGQNFIPPKKPKTFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPG 128
           G  PD  KR  + +G N +P ++ KT  +LV E  +D+ + IL +AA IS  L+++    
Sbjct: 23  GLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRILLLAACISFVLAWF---- 78

Query: 129 EGNEGCATAQGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQSRIEQ 188
                        E+  E    ++E   ILL +I   +V  + + + E     L+    +
Sbjct: 79  -------------EEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALKEYEPE 125

Query: 189 EQKFTVVRAGQVVQIPVAEIVVGDIAQVKYGDLLPAD--GLFIQGNDLKIDESSLTGESD 246
             K        V +I   +IV GDI +V  GD +PAD   L I+   L++D+S LTGES 
Sbjct: 126 MGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILTGESV 185

Query: 247 QVRK-----------SVDKDPMLLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEE 295
            V K           + DK  ML SGT++  G    +V   GV ++ G I   + A  ++
Sbjct: 186 SVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAATEQD 245

Query: 296 EEKKDKKGVKKGDGL 310
           +    +K  + G+ L
Sbjct: 246 KTPLQQKLDEFGEQL 260


>gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo
           sapiens]
          Length = 1023

 Score =  231 bits (590), Expect = 2e-60
 Identities = 214/727 (29%), Positives = 339/727 (46%), Gaps = 87/727 (11%)

Query: 289 LGAGGEEEEKKDKKGVKKGDGLQLPAADGAAASNAADSANASLVN-GKMQDGNVDASQSK 347
           +    EE    D   VK GD  ++PA     ++N     N+SL    + Q  + D +   
Sbjct: 178 MSINAEEVVVGDLVEVKGGD--RIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNEN 235

Query: 348 AKQQDGAAAMEMQPLKSAEGGDA---DDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVM 404
             +    A      ++    G      DR          S L+G  T +A +I     ++
Sbjct: 236 PLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHII 295

Query: 405 SAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVT 464
           + + V + V +F +   ++ +  WL              F+IG+  +V  VPEGL   VT
Sbjct: 296 TGVAVFLGVSFFILS--LILEYTWLEAV----------IFLIGI--IVANVPEGLLATVT 341

Query: 465 ISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKE 523
           + L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +  + +H  +
Sbjct: 342 VCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEAD 401

Query: 524 IPDPSS----INTKTMELLINAIAINSAYTTKILPPEKEGALPRQV-GNKTECGLL---- 574
             +  S      T    L ++ IA            E    L R V G+ +E  LL    
Sbjct: 402 TTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIE 461

Query: 575 ---GFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDES---FRMYSKGAS 628
              G V ++++ Y  +  ++P         FNS  K   ++ K P+ S     +  KGA 
Sbjct: 462 LCCGSVKEMRERYAKI-VEIP---------FNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 511

Query: 629 EIVLKKCCKIL-NGAGEPRVFRPRDRDEMVKKVIEPMACD---------GLRTICVAYRD 678
           E +L +C  IL +G  +P        DE +K   +    +         G   + +    
Sbjct: 512 ERILDRCSSILLHGKEQPL-------DEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQ 564

Query: 679 FPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTA 738
           FP   + D D+ N  ++ L  + ++ + DP R  VP+A+ KC+ AGI V MVTGD+  TA
Sbjct: 565 FPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITA 624

Query: 739 RAIAIKCGIIHPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERIDKI--W 782
           +AIA   GII  G +        L +   + N R         ++  ++  E++D I  +
Sbjct: 625 KAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKY 684

Query: 783 PKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGT 842
               V AR+SP  K  +V+G        Q  +VAVTGDG ND PALKKAD+G AMGIAG+
Sbjct: 685 HTEIVFARTSPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGS 739

Query: 843 DVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD 902
           DV+K+A+D+IL DDNF+SIV  V  GR ++D++ K + + LT N+  +            
Sbjct: 740 DVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIP 799

Query: 903 SPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQ 962
            PL  V +L ++L  D   +++LA E     ++ R+P     P   + + + ++  A  Q
Sbjct: 800 LPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTDKLVNERLISMAYGQ 856

Query: 963 LALIFTL 969
           + +I  L
Sbjct: 857 IGMIQAL 863



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 50/160 (31%), Positives = 86/160 (53%), Gaps = 13/160 (8%)

Query: 138 QGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVR 196
           Q   E+E + +  ++    ++LS + V++   F+ + + K  + ++S +    Q+  V+R
Sbjct: 118 QAATEEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR 173

Query: 197 AGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD--- 253
            G+ + I   E+VVGD+ +VK GD +PAD   I  N  K+D SSLTGES+   +S D   
Sbjct: 174 NGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTN 233

Query: 254 KDPM-----LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTL 288
           ++P+         T+ +EG+ R +V   G  +  G I TL
Sbjct: 234 ENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 273


>gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo
           sapiens]
          Length = 992

 Score =  231 bits (590), Expect = 2e-60
 Identities = 214/727 (29%), Positives = 339/727 (46%), Gaps = 87/727 (11%)

Query: 289 LGAGGEEEEKKDKKGVKKGDGLQLPAADGAAASNAADSANASLVN-GKMQDGNVDASQSK 347
           +    EE    D   VK GD  ++PA     ++N     N+SL    + Q  + D +   
Sbjct: 147 MSINAEEVVVGDLVEVKGGD--RIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNEN 204

Query: 348 AKQQDGAAAMEMQPLKSAEGGDA---DDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVM 404
             +    A      ++    G      DR          S L+G  T +A +I     ++
Sbjct: 205 PLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHII 264

Query: 405 SAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVT 464
           + + V + V +F +   ++ +  WL              F+IG+  +V  VPEGL   VT
Sbjct: 265 TGVAVFLGVSFFILS--LILEYTWLEAV----------IFLIGI--IVANVPEGLLATVT 310

Query: 465 ISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKE 523
           + L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +  + +H  +
Sbjct: 311 VCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEAD 370

Query: 524 IPDPSS----INTKTMELLINAIAINSAYTTKILPPEKEGALPRQV-GNKTECGLL---- 574
             +  S      T    L ++ IA            E    L R V G+ +E  LL    
Sbjct: 371 TTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIE 430

Query: 575 ---GFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDES---FRMYSKGAS 628
              G V ++++ Y  +  ++P         FNS  K   ++ K P+ S     +  KGA 
Sbjct: 431 LCCGSVKEMRERYAKI-VEIP---------FNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480

Query: 629 EIVLKKCCKIL-NGAGEPRVFRPRDRDEMVKKVIEPMACD---------GLRTICVAYRD 678
           E +L +C  IL +G  +P        DE +K   +    +         G   + +    
Sbjct: 481 ERILDRCSSILLHGKEQPL-------DEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQ 533

Query: 679 FPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTA 738
           FP   + D D+ N  ++ L  + ++ + DP R  VP+A+ KC+ AGI V MVTGD+  TA
Sbjct: 534 FPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITA 593

Query: 739 RAIAIKCGIIHPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERIDKI--W 782
           +AIA   GII  G +        L +   + N R         ++  ++  E++D I  +
Sbjct: 594 KAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKY 653

Query: 783 PKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGT 842
               V AR+SP  K  +V+G        Q  +VAVTGDG ND PALKKAD+G AMGIAG+
Sbjct: 654 HTEIVFARTSPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGS 708

Query: 843 DVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD 902
           DV+K+A+D+IL DDNF+SIV  V  GR ++D++ K + + LT N+  +            
Sbjct: 709 DVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIP 768

Query: 903 SPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQ 962
            PL  V +L ++L  D   +++LA E     ++ R+P     P   + + + ++  A  Q
Sbjct: 769 LPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTDKLVNERLISMAYGQ 825

Query: 963 LALIFTL 969
           + +I  L
Sbjct: 826 IGMIQAL 832



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 50/160 (31%), Positives = 86/160 (53%), Gaps = 13/160 (8%)

Query: 138 QGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVR 196
           Q   E+E + +  ++    ++LS + V++   F+ + + K  + ++S +    Q+  V+R
Sbjct: 87  QAATEEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR 142

Query: 197 AGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD--- 253
            G+ + I   E+VVGD+ +VK GD +PAD   I  N  K+D SSLTGES+   +S D   
Sbjct: 143 NGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTN 202

Query: 254 KDPM-----LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTL 288
           ++P+         T+ +EG+ R +V   G  +  G I TL
Sbjct: 203 ENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 242


>gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens]
          Length = 1023

 Score =  231 bits (590), Expect = 2e-60
 Identities = 214/727 (29%), Positives = 339/727 (46%), Gaps = 87/727 (11%)

Query: 289 LGAGGEEEEKKDKKGVKKGDGLQLPAADGAAASNAADSANASLVN-GKMQDGNVDASQSK 347
           +    EE    D   VK GD  ++PA     ++N     N+SL    + Q  + D +   
Sbjct: 178 MSINAEEVVVGDLVEVKGGD--RIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNEN 235

Query: 348 AKQQDGAAAMEMQPLKSAEGGDA---DDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVM 404
             +    A      ++    G      DR          S L+G  T +A +I     ++
Sbjct: 236 PLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHII 295

Query: 405 SAITVIILVLYFTVDTFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVT 464
           + + V + V +F +   ++ +  WL              F+IG+  +V  VPEGL   VT
Sbjct: 296 TGVAVFLGVSFFILS--LILEYTWLEAV----------IFLIGI--IVANVPEGLLATVT 341

Query: 465 ISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKE 523
           + L  + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV   +  + +H  +
Sbjct: 342 VCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEAD 401

Query: 524 IPDPSS----INTKTMELLINAIAINSAYTTKILPPEKEGALPRQV-GNKTECGLL---- 574
             +  S      T    L ++ IA            E    L R V G+ +E  LL    
Sbjct: 402 TTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIE 461

Query: 575 ---GFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVIKLPDES---FRMYSKGAS 628
              G V ++++ Y  +  ++P         FNS  K   ++ K P+ S     +  KGA 
Sbjct: 462 LCCGSVKEMRERYAKI-VEIP---------FNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 511

Query: 629 EIVLKKCCKIL-NGAGEPRVFRPRDRDEMVKKVIEPMACD---------GLRTICVAYRD 678
           E +L +C  IL +G  +P        DE +K   +    +         G   + +    
Sbjct: 512 ERILDRCSSILLHGKEQPL-------DEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQ 564

Query: 679 FPSSPEPDWDNENDILNELTCICVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTA 738
           FP   + D D+ N  ++ L  + ++ + DP R  VP+A+ KC+ AGI V MVTGD+  TA
Sbjct: 565 FPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITA 624

Query: 739 RAIAIKCGIIHPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERIDKI--W 782
           +AIA   GII  G +        L +   + N R         ++  ++  E++D I  +
Sbjct: 625 KAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKY 684

Query: 783 PKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGT 842
               V AR+SP  K  +V+G        Q  +VAVTGDG ND PALKKAD+G AMGIAG+
Sbjct: 685 HTEIVFARTSPQQKLIIVEGC-----QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGS 739

Query: 843 DVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQD 902
           DV+K+A+D+IL DDNF+SIV  V  GR ++D++ K + + LT N+  +            
Sbjct: 740 DVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIP 799

Query: 903 SPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQ 962
            PL  V +L ++L  D   +++LA E     ++ R+P     P   + + + ++  A  Q
Sbjct: 800 LPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQP---RNPKTDKLVNERLISMAYGQ 856

Query: 963 LALIFTL 969
           + +I  L
Sbjct: 857 IGMIQAL 863



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 50/160 (31%), Positives = 86/160 (53%), Gaps = 13/160 (8%)

Query: 138 QGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVR 196
           Q   E+E + +  ++    ++LS + V++   F+ + + K  + ++S +    Q+  V+R
Sbjct: 118 QAATEEEPQNDNLYL---GVVLSAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR 173

Query: 197 AGQVVQIPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD--- 253
            G+ + I   E+VVGD+ +VK GD +PAD   I  N  K+D SSLTGES+   +S D   
Sbjct: 174 NGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTN 233

Query: 254 KDPM-----LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTL 288
           ++P+         T+ +EG+ R +V   G  +  G I TL
Sbjct: 234 ENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATL 273


>gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo
           sapiens]
          Length = 1029

 Score =  227 bits (578), Expect = 6e-59
 Identities = 181/563 (32%), Positives = 276/563 (49%), Gaps = 61/563 (10%)

Query: 444 FIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGT 503
           F+IG+  +V  VPEGL   VT+ L  + K+M + N LV++L+A ET+G+ + ICSDKTGT
Sbjct: 331 FLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGT 388

Query: 504 LTTNRMTV------VQAYVGDVHYKEIPDPSSINTKTMELLINAIAINSAYTTK----IL 553
           LT NRMTV      +  Y  D   ++     + ++ T  +L     + +    K    IL
Sbjct: 389 LTQNRMTVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEIL 448

Query: 554 PPEKEGALPRQVGNKTECGLLGFVLDLKQDYEPVRSQMPEEKLYKVYTFNSVRKSMSTVI 613
           P  K        G+ +E  LL F+   +Q Y  V     +        FNS  K   ++ 
Sbjct: 449 PIAKRAT----TGDASESALLKFI---EQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIH 501

Query: 614 KLPDES--FRMYSKGASEIVLKKCCKILNGAGEPRVFRPRDRDEMVKKVIEPMACDGLRT 671
              D S    +  KGA E +L+ C   L    E  +    +  E  +     +   G R 
Sbjct: 502 LREDSSQTHVLMMKGAPERILEFCSTFLLNGQEYSM--NDEMKEAFQNAYLELGGLGERV 559

Query: 672 ICVAYRDFPSSPEPDWDNENDILN-ELTCICVVGI---EDPVRPEVPEAIRKCQRAGITV 727
           +   + + PSS    +    D +N  +  +C VG+    DP R  VP+A+ KC+ AGI V
Sbjct: 560 LGFCFLNLPSSFSKGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKV 619

Query: 728 RMVTGDNINTARAIAIKCGIIHPGEDFLCLEGKEFNRRIR------------------NE 769
            MVTGD+  TA+AIA   GII  G +      +E   R++                   E
Sbjct: 620 IMVTGDHPITAKAIAKGVGIISEGTE----TAEEVAARLKIPISKVDASAAKAIVVHGAE 675

Query: 770 KGEIEQERIDKI---WPKLRVLARSSPTDKHTLVKGIIDSTHTEQRQVVAVTGDGTNDGP 826
             +I+ +++D+I    P++ V AR+SP  K  +V+G           VVAVTGDG ND P
Sbjct: 676 LKDIQSKQLDQILQNHPEI-VFARTSPQQKLIIVEGC-----QRLGAVVAVTGDGVNDSP 729

Query: 827 ALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKAVMWGRNVYDSISKFLQFQLTVN 886
           ALKKAD+G AMGI+G+DV+K+A+D+IL DDNF+SIV  V  GR ++D++ K + + LT N
Sbjct: 730 ALKKADIGIAMGISGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSN 789

Query: 887 VVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLALATEPPTETLLLRKPYGRNKPL 946
           +  +        +    PL  + +L ++L  D   +++LA E     ++ R P     P 
Sbjct: 790 IPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMKRLP---RNPK 846

Query: 947 ISRTMMKNILGHAVYQLALIFTL 969
               +   ++G A  Q+ +I  L
Sbjct: 847 TDNLVNHRLIGMAYGQIGMIQAL 869



 Score = 72.0 bits (175), Expect = 3e-12
 Identities = 48/142 (33%), Positives = 83/142 (58%), Gaps = 10/142 (7%)

Query: 156 AILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVRAGQVVQIPVAEIVVGDIA 214
           +I+LSV+ V++   F+ + + K  + ++S +    Q+  V+R G+ +QI V E+V+GD+ 
Sbjct: 141 SIVLSVV-VIVTGCFSYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLV 199

Query: 215 QVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-----LLSGTHVME 266
           ++K GD +PAD   I     K+D SSLTGES+   +S D   ++P+         T+ +E
Sbjct: 200 EIKGGDRVPADLRLISAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVE 259

Query: 267 GSGRMLVTAVGVNSQTGIIFTL 288
           G+ R +V A G ++  G I +L
Sbjct: 260 GTARGIVIATGDSTVMGRIASL 281


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,699,566
Number of Sequences: 37866
Number of extensions: 2124386
Number of successful extensions: 7260
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 23
Number of HSP's that attempted gapping in prelim test: 6787
Number of HSP's gapped (non-prelim): 325
length of query: 1243
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1129
effective length of database: 13,930,794
effective search space: 15727866426
effective search space used: 15727866426
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.